LOCUS       c00002_gnlPro..        15314 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MLFELBAE_2.
ACCESSION   c00002_gnlPro..
VERSION     c00002_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 23:49:00
            Original ID  :: gnl|Prokka|MLFELBAE_2
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15314
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15314
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2023:5314]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2024..5314
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..15314
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15314
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(2..334)
                     /locus_tag="ctg2_1"
                     /transl_table=11
                     /translation="MGTRVSYPVEVKQKAVEMRLAGVPMKEILQELNIKNKTQVQTWVR
                     WYKAGDTHRFEQPVGKQYSYGKGPEYSSELEKLQAENRYLRQQNEVLKKYNELERKLIA
                     KRQSSL"
     CDS             654..839
                     /locus_tag="ctg2_2"
                     /transl_table=11
                     /translation="LKYAFAYKNRNIETIFCGKDELFEELKQFLITQCGLIIVEVSRAD
                     YYTEQEMNQWNDRYTL"
     CDS             complement(879..1229)
                     /locus_tag="ctg2_3"
                     /transl_table=11
                     /translation="MNKMLSGMQGLPPGFPPLPVLPPQSYYPPAPMHTAPYQGGPSFQQ
                     GFPSSGYGQQTPQSTLSFAGQQFVPYPYTTGYYGQSFSDVGGSLGAGAHPGALGGGFSG
                     HAGGFSAPSGFR"
     CDS             2024..3748
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_4"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.7e-54, bitscore:
                     178.2, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGTNVQADSLSAECTKTMNGALMLIESLKKENVEMIFGYPGGAVL
                     PIYDKLYQSGLVHILPRHEQGAIHAAEGYARVSGKPGVVIATSGPGATNLVTGLADAMI
                     DSLPLVVFTGQVATSVIGSDAFQEADILGITMPITKHSYQVRRPEDLPRVIKEAFHIAT
                     TGRPGPVLIDIPKDVAAFEGEFRYDHEISLPGYQPVKEPNYLQIRKLVEAVSSAKKPVI
                     LAGAGVLHGKASEDLKNYVEQQQIPVAHTLLGLGGFPADHPLFLGMAGMHGTYTANMAL
                     YHCDLLISIGARFDDRVTGNLKHFAKSAKVAHIDIDPAEIGKIIETQIPVVGDSKIVLQ
                     ELLKQNGKQGQTEEWKQQLSEWKEEYPLWYTDNREEGLKPQKLIEYIHQFTNGEAIVAT
                     DVGQHQMWAAQFYPFRKADKWVTSGGLGTMGFGLPAAIGAQLADRNATVVAILGDGGFQ
                     MTLQELDVIRQLNLPVKVVILNNECLGMVRQWQEIFYEERYSESKFSAQPDFVKLSEAY
                     GIKGVRISSEEEAEEELKKVLSSKEPAVIDVRVAKSEKVFPMIAPGKGLHEMVGVKP"
     CDS             3745..4263
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_5"
                     /sec_met_domain="ALS_ss_C (E-value: 1e-30, bitscore: 100.2,
                     seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LKRIITLTVVNRSGVLNRITGLFTKRHYNIESITVGHTETSGVSR
                     ITFVVHVEGENDVEQLTKQLNKQIDVLKVTDITNQSIVQRELALIKVVSAPSARTEING
                     IIEPFRASVVDVSRDSIVVQVTGESNKIEALIELLKPYGIKEIARTGTTAFARGTQQKA
                     SSNKTISIV"
     CDS             4286..5314
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_6"
                     /sec_met_domain="IlvN (E-value: 4.1e-78, bitscore: 255.1,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 7e-68, bitscore: 221.9,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKVYYNGDIKENVLAGKKVAIIGYGSQGHAHALNLKESGIDVIV
                     GVRQGKSFTQAQEDGHKVFSVREAAAQADIIMVLLPDEQQQKVYEAEIKDELTAGKSLV
                     FAHGFNVHFHQIVPPADVDVFLVAPKGPGHLVRRTYEQGAGVPALFAIYQDVSGEAKDT
                     ALAYAKGIGGARAGVLETTFKEETETDLFGEQAVLCGGLTALVKAGFETLTEAGYQPEL
                     AYFECLHELKLIVDLMYEEGLAGMRYSISDTAQWGDFVSGPRVVDAKVKESMKQVLTDI
                     QNGTFAKEWIVENQVNRPRFNAINASENEHQIEKVGRQLREMMPFVKQGKKKEAVVSVA
                     QN"
     CDS             5301..6857
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_7"
                     /sec_met_domain="HMGL-like (E-value: 1.1e-97, bitscore:
                     321.2, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LRKINVFDTTLRDGEQSPGVNLNSREKLAIAKQLERLGVDIIEAG
                     FPASSRGDFLAVQEIARTIKNCSVTGLARSVKGDIDAAWEALKDGASPRIHIFIATSDI
                     HLKHKLKMTREEVKEKAVEMVKYAKERFPIVQWSAEDACRTELPFLAEIVEEVIDAGAS
                     VINLPDTVGYLTPAEYGNIFKYMKEHVPNINRVKLSAHCHDDLGMAVANSLSAIENGAD
                     QIECAINGIGERAGNAALEEIAVALHVRNDAHQADSSLNLHELKRTSDLVSKLTGMAVP
                     RNKAIVGDNAFAHESGIHQDGFLKEKSTYEIISPELVGVTADALVLGKHSGRHAFKDRL
                     NTLGFQFDSDEINKYFTMFKELTEKKKEITDDDLISLILEEKVTDKKIGYEFLSLQVHY
                     GTSQVPTATVSLKNQENEQLMQEAATGAGSVEAVYNTLGRCIDKNIELTDYRIQSNRKG
                     EDALAQVYVRVTVNGKETSGRGIAQDVLEASAKAYLNAVNRQLVLDCNLDGLKRQTAVG
                     S"
     CDS             6878..7975
                     /locus_tag="ctg2_8"
                     /transl_table=11
                     /translation="LKKRIALLPGDGIGPEVAESAADVLKSVAEQFGHEFEFENGLIGG
                     AAIDAHQNPLPEETVALCERSDAILLGAVGGPKWDQNPPELRPEKGLLGIRKKLGLFAN
                     LRPVTVFESLSEASPLKKEYISGVDFVIVRELTGGLYFGEPSRQYVNEAGEKEAVDTLF
                     YKKEEIARVVREAFKMAAGRKGKVTSVDKANVLSSSRLWRETANEIAKEFPDVTLEHML
                     VDNAAMQLIYAPSQFDVIVTENMFGDILSDEASMLTGSLGMLPSASLSSSGLHLFEPVH
                     GSAPDIAGKGMANPFAAILSAAMLLRTSFGLENEAQAVEKAVAKVLADGSRTRDIARDG
                     QYAGTHDITEKVKAALAGSNTKSIV"
     CDS             8025..9443
                     /locus_tag="ctg2_9"
                     /transl_table=11
                     /translation="MMPRTIIEKIWDRHVVKSGEGKPDLLYIDLHLIHEVTSPQAFEGL
                     RQKGRKVRRPQNTFATMDHNIPTVNRFDIKDEVAKRQVTALERNCEEFGVRLADLHSAD
                     QGIVHVVGPELGLTLPGKTIVCGDSHTSTHGAFGALAFGIGTSEVEHVLSTQTLWQQRP
                     KTLEIRVDGTLQKGVTAKDVILSVIGKYGVKFGTGYVIEYTGEVFRNMSMDERMTVCNM
                     SIEAGARAGLIAPDDTTIEYCKNRKYAPKGEEFEKAAAEWKALKTDPGAVYDHSIVLDG
                     SEISPMVTWGVNPGMVLPVDAQIPAPETIDSEDGKKEAIRAYEYMGISPNQKIEDIKVE
                     HVFIGSCTNSRMTDLRQAADMIKGRKVADSVRAIVVPGSQSVKQQAEEEGLHRVFLEAG
                     FEWRESGCSMCLSMNNDVVPEGERCASTSNRNFEGRQGKGARTHLVSPAMAAMAAIHGH
                     FVDVRKFYQEKTVV"
     CDS             9459..10058
                     /locus_tag="ctg2_10"
                     /transl_table=11
                     /translation="MEPLKTHTGKAAVLNRINVDTDQIIPKQFLKRIERTGYGRFAFFD
                     WRYLENGEPDPEFELNRKVYEGASILIAGENFGCGSSREHAPWALDDYGFKIIIAPSFA
                     DIFHQNCFKNGMLPIRMPYDQWKKLAGQYENQSLNMMVDLENQLIHDSEGKEISFEVDP
                     HWKEMLINGYDEISLTLLLEDDIQQFESKRSSWLQA"
     CDS             10175..11179
                     /locus_tag="ctg2_11"
                     /transl_table=11
                     /translation="MTHDKKKADIIPFPRLKERLVDKGMAAMKDKQYQEALELFSEAVS
                     HGDTESDVHLGMAICFLELGELEEAKQVCEKMLNEGYGHYFTVLQVYMTILIQLKQYEE
                     VKSTIEAVLEENQLPAESAEQFYRLLEFSRKMTDPDQQDEAWEEEYEDILDAEKVLNSP
                     AEQMNLIHSLKDRNIAKYTGLLKTILQDPGAHPLIKTMILTLMAEHDYSKPVHITKFGD
                     SMTAVPSETVQPDAAPILHRVLRVLDETLGNENPTLYAAVEELWRRHLYVLHPFMPKFL
                     NADLWAAALHKVGYEMHGIDIEQEELHMMYEFDSRELEEACTMIKDIEEISYL"
     CDS             11396..12670
                     /locus_tag="ctg2_12"
                     /transl_table=11
                     /translation="MSVKWEKQEGNEGVLTVEVDADTFKTALDDAFKKVVKQVSIPGFR
                     KGKVPRGLFEQRFGVEALYQDALDILLPVEYPKAVEEAGIEPVDRPEIDVEKIEKGESL
                     IFTAKVTVKPEVKLGDYKGLGIEKDDTAVTDEDVQNELKALQERQAELVVKEEGAVENG
                     DTVVLDFEGFVDGEAFEGGKAENYSLEVGSGSFIPGFEEQLTGLEAGAEKDVEVTFPEE
                     YHAEELAGKPAIFKVKIHEIKAKELPELNDEFAKDIDEEVETLAELTEKTKKRLEEAKE
                     NEADAKLREELVLKASENAEADVPQAMIDTELDRMLKEFEQRLQMQGMNLELYTQFSGQ
                     DENALKEQMKEDAAKRVKSNLTLEAIAQAENLEVTDEEVEAELTKMAEAYNMPVENIKQ
                     AIGSTDAMKEDLKVRKAIDFLVENR"
     CDS             12942..14204
                     /locus_tag="ctg2_13"
                     /transl_table=11
                     /translation="MFKFNEEKGQLKCSFCGKTQDQVRKLVAGPGVYICDECIELCTEI
                     VEEELGTEEEVEFKDVPKPQEIREILNEYVIGQDQAKKSLAVAVYNHYKRINSNSKVDD
                     VELSKSNISLIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLI
                     QAADYDVEKAEKGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQ
                     GGRKHPHQEFIQIDTTNILFICGGAFDGIEQIIKRRLGQKVIGFGSDNKAADLEKEELL
                     SKVLPEDLLRFGLIPEFIGRLPVIASLEQLDETALVEILTKPKNALVKQYKKMLELDDV
                     ELEFEDEALSEIAKKAIERKTGARGLRSIIEGIMLDVMFDLPSRDDIEKCVITGATVAD
                     GEAPRLVLKDGTVVGQDKTSA"
ORIGIN
        1 tctacaagct cgactggcgt ttcgctatca gcttcctttc caattcgttg tactttttta
       61 acacttcatt ctgttgtctc agataacgat tttctgcctg cagtttctct aattcggaag
      121 aatactccgg accttttcca taagaatatt gctttccgac aggttgttcg aatcgatgtg
      181 tgtccccagc tttataccac ctgacccatg tctgcacctg cgtcttattc tttatattca
      241 attcctgcag gatctctttc ataggtacgc ctgccaatct catttctaca gccttctgtt
      301 tcacttcaac cggataactc actcttgtcc ccatagaaaa aacacctcca agtctaattt
      361 cggataacaa tcatccgtat tcaaacttga aggtgttttt atttgtctca tattatgggg
      421 tcagtcccat gggtttgagg tttttttgta ttttattttt attttacaaa acaaaagttc
      481 cgtatttgat gaaaattgta aagtaatttt aatataaatg aaacttaatg taatatttac
      541 cgtaataaat atatgtataa agatacttaa ggcgcccttg agtgaaaaat tatctaattt
      601 ctatcataca ttttgtcaat gaatgataga aagacagcag gaggaattag cttttgaagt
      661 acgcatttgc atataaaaat cgcaatatag aaacgatctt ttgcggaaaa gacgagctgt
      721 ttgaggaact gaagcaattt ttaatcactc aatgcggttt aatcattgtt gaggtttcaa
      781 gggctgatta ctatacggag caggaaatga atcagtggaa tgaccgttat actttgtgaa
      841 tatgaaaaga aaccggccgt gggaggccgg ttttagtatc atctgaatcc gctcggagcg
      901 ctgaagcccc cggcatggcc gctgaaaccg cccccgagcg cgccgggatg cgccccggcg
      961 ccgaggcttc cgccgacgtc actgaaggat tggccgtagt acccggttgt ataagggtac
     1021 ggaacgaatt gctgcccggc gaatgacagc gtgctttgcg gggtctgctg tccgtatccg
     1081 gatgacggga atccctgctg aaaagaaggg ccgccttgat atggtgctgt atgcatcgga
     1141 gccggaggat aataagactg cggcggtaag accggtaaag gcggaaatcc aggaggcagg
     1201 ccctgcatgc ctgataacat cttattcatg acatcactca tttcttacga gataagaaca
     1261 gtgtatgcgt atgtctgtag aaagagcctg ttcaatcgat cggaatatct gacaagcatg
     1321 ccggaaggac agagaaaaat cgtgtaataa aatgtgacat attcgtatat gaacggaaaa
     1381 atttcatgta atcttgagag attaataaaa aaatgataaa aacttttaat atttacagat
     1441 ccctttgtac cagtaatgaa agcgtataca aagtagattg attaatctaa attgtctaat
     1501 aattataaaa atgctgttga cactgcctgc aaacgggcgt aatatgagtt caaacaaaaa
     1561 taaataaatg attcacgcta aaaagaaaaa tcataaaaca ctgaaaaaac aaacaagtga
     1621 aggttctttt ttaataaaag agctgccata ataaaaagcg cagaagagga taagtagctt
     1681 tgctgaagtt tttcacagag agccggtaac gctgagagcc ggtaaaacaa atcaaagtga
     1741 actcccctca gagtgccggg ctgaaatgta aagagtagga ctcggccgag tgaacgcaat
     1801 gtttactcgt tatcaaaacg gataatcatt atccatgaga cggtctgcat atgaccgtaa
     1861 acaagggtgg taccgcggag agcaaagcct tttcgcccct tttggctatc gcatgaaatg
     1921 cttggctgaa tgtgggtggg aaaggctttt ttatttgcgt cagccggcgc tgcgttttat
     1981 gaattagatt ttagaaggga acattgaaaa ggaggaactg aaaatgggca caaatgtaca
     2041 ggcggattct ttgtctgccg aatgtacaaa aacaatgaac ggggctctga tgctgattga
     2101 atcattaaag aaagaaaatg tcgagatgat cttcggctat ccggggggag ccgtccttcc
     2161 gatttacgat aaactgtatc aatcaggatt ggttcacatc ctgccccgcc acgagcaagg
     2221 cgcgattcat gcggcagaag ggtatgcgag agtctccgga aagccggggg ttgtgattgc
     2281 tacctccgga cccggagcga caaatttagt taccggtctt gcggatgcga tgatagattc
     2341 attgccgctc gtagtgttta ccggtcaggt ggccacttcg gtcatcggca gcgacgcttt
     2401 ccaggaagcc gacattttag gaattacgat gccgattacg aaacacagct accaagtccg
     2461 ccgtccggaa gatctccccc gtgtgattaa agaggcgttc catatcgcca cgacgggaag
     2521 accgggtccg gtattaattg atataccgaa ggatgtcgca gcatttgaag gagagttcag
     2581 atatgatcac gagatcagcc ttccgggtta tcagcctgta aaagagccta actatctgca
     2641 gatccgaaag ctcgtggaag ctgtcagcag tgcgaaaaag ccggttattt tagccggagc
     2701 gggtgttttg cacggtaaag cttcagaaga tttaaaaaat tatgtcgaac agcagcaaat
     2761 tccggtagcg cacacgctcc tcggtctggg cggtttcccg gcagaccatc ctctttttct
     2821 gggaatggcg gggatgcacg gcacatacac agcgaatatg gcgctttacc actgtgactt
     2881 gttgatcagc atcggagcgc ggttcgatga tcgcgtgacc ggaaatctga agcattttgc
     2941 aaaatcggcc aaagtggcgc atatcgatat tgatcctgct gaaatcggaa aaattatcga
     3001 aacgcagatt ccggtggtcg gcgacagtaa aatcgtcctt caggaattat tgaagcaaaa
     3061 cggaaaacag ggacagacag aggaatggaa acagcagctt tcagaatgga aagaagaata
     3121 tccgctttgg tatacagaca acagagaaga gggcttgaaa ccccaaaagc tgattgagta
     3181 tattcaccaa ttcacaaacg gtgaggcaat tgtggcgacg gatgtcggcc agcaccagat
     3241 gtgggcggct cagttttatc ctttccgaaa ggctgataag tgggtgacct cgggggggct
     3301 cggcacaatg ggcttcggcc ttccggcggc tatcggagcg cagctggccg atcgtaacgc
     3361 cacggtcgtt gccatcctcg gagacggcgg ttttcagatg acccttcagg aattagatgt
     3421 catccggcag ctgaatcttc ctgtcaaagt ggttatcttg aacaacgaat gtctgggcat
     3481 ggtcagacag tggcaggaaa tcttctatga agagcgctat tctgaatcca aattctcggc
     3541 gcagcctgac tttgtcaaat tgtcagaagc ctacggcatt aaaggcgtcc ggatttcatc
     3601 ggaggaagag gcggaagaag agcttaaaaa ggtgctttca tcaaaagaac cggccgttat
     3661 tgacgtccgg gtcgccaaaa gcgagaaagt attcccgatg attgcgccgg gtaaaggact
     3721 tcatgaaatg gtgggggtga aaccttgaaa cgcattatca cattaacggt ggtcaaccgc
     3781 tcgggagtat taaaccggat caccggcctg tttacaaaaa gacactataa tatcgaaagc
     3841 atcactgtag gccacacgga aacaagcggt gtttcaagga ttacatttgt cgtccatgtg
     3901 gaaggcgaaa atgacgtaga gcagctgaca aagcagctta acaaacaaat tgacgtcctg
     3961 aaagtgacgg atattacaaa ccaatcgatt gtacagcgtg agctggcatt aatcaaagtt
     4021 gtttccgcac cgtcggccag aacggaaatc aatggaatca ttgagccgtt cagagcttcc
     4081 gtcgttgatg tctcaagaga cagcatcgtc gttcaggtta ccggcgaatc taataaaatc
     4141 gaagcgctca tagagctgct caaaccttac ggcattaaag aaatcgcgag aacaggcaca
     4201 acggcttttg cgaggggaac ccagcagaag gcgtcatcca ataaaacaat ttcaattgta
     4261 taacacaaaa aagggagaga ttaaaatggt aaaagtatat tataacggtg atatcaaaga
     4321 gaacgtattg gcaggtaaaa aagtagcgat tatcggttac ggttcacaag gtcacgcaca
     4381 tgcgctgaat ttaaaagaaa gcggaattga tgtcattgtc ggcgtcagac aaggaaaatc
     4441 atttacacag gcccaagaag acggtcataa agtcttttcg gtaagagaag cggctgccca
     4501 ggcagatatc attatggttc ttcttccgga tgaacagcag caaaaagtat atgaagctga
     4561 aatcaaagat gaattgacgg cgggcaagtc attagtattc gcacacggat ttaacgtcca
     4621 tttccatcag atcgtgcctc ctgctgatgt ggatgtattc cttgtcgccc ctaaaggacc
     4681 gggacacctt gtcagaagaa catatgaaca aggcgcgggc gtaccggcat tgtttgccat
     4741 ctaccaggat gtatcaggcg aagcgaaaga tacggctctt gcttatgcaa aaggaatcgg
     4801 cggagcgcgt gcgggcgttc ttgaaacaac atttaaggaa gaaacggaaa cggatttgtt
     4861 cggtgagcag gctgttctgt gcggaggttt aacggcgctt gtcaaagcgg gttttgaaac
     4921 gctgacagaa gccggctacc agcctgaact cgcatacttc gagtgtctgc acgaactgaa
     4981 gttgatcgta gacttgatgt atgaagaagg attggcgggc atgagatact ctatctccga
     5041 tacggctcaa tggggagatt ttgtctcagg gccgcgcgta gtcgatgcga aggtaaaaga
     5101 atcgatgaaa caagtattaa cagatattca aaacggtaca ttcgcgaaag aatggatcgt
     5161 ggaaaaccaa gtgaaccgtc ctcgcttcaa tgcgatcaat gctagtgaaa acgagcatca
     5221 gattgaaaag gtcggcagac agcttcgtga aatgatgccg tttgtcaaac aaggcaaaaa
     5281 gaaggaagcg gtggtctccg ttgcgcaaaa ttaatgtttt cgacacgacc cttcgtgacg
     5341 gtgaacaatc ccccggggtc aacctcaatt cccgggagaa actggcgata gccaagcagc
     5401 ttgaaagact cggggtggat attattgaag cgggatttcc cgcttcatcc cgaggtgatt
     5461 ttttagccgt gcaggaaatc gcaagaacga ttaaaaattg ttcggtaaca gggcttgccc
     5521 gatctgtcaa aggtgacatc gacgcagcct gggaagcgct gaaagacggg gccagcccgc
     5581 ggattcacat ttttatcgcc acctctgaca ttcatctgaa gcataagctg aaaatgacgc
     5641 gggaagaggt taaggaaaaa gcggttgaaa tggtgaagta tgcaaaagaa cgctttccga
     5701 tcgttcaatg gtcagcagaa gacgcatgcc gcaccgaact tccgtttctg gctgaaatcg
     5761 ttgaagaagt gattgatgcc ggcgcgagcg tcatcaacct gccggacact gtaggttacc
     5821 tgacgccggc tgaatacgga aacatcttta aatatatgaa ggaacacgtt ccgaatatca
     5881 accgggtaaa gctttcagcc cattgccacg atgatctcgg aatggcggtt gccaactcgc
     5941 tttcggcaat tgagaacggc gctgatcaaa ttgaatgcgc cattaacggc ataggagaaa
     6001 gagccgggaa cgccgcgcta gaggaaatcg ctgttgcgct tcatgtcaga aatgacgcgc
     6061 atcaagccga ttcatccctc aatcttcatg aattgaagcg gacgagtgat cttgtcagca
     6121 aactgacggg catggccgtt ccccgcaata aagcaatcgt cggagataac gctttcgcac
     6181 atgagtccgg cattcaccaa gacggtttcc tgaaagaaaa atcaacatat gaaatcattt
     6241 caccggaact tgtcggcgtg actgctgatg cgctcgtact cggaaagcat tccgggcgcc
     6301 acgcgttcaa agaccgcctg aatacgcttg gattccagtt tgatagtgat gaaatcaata
     6361 aatattttac gatgtttaaa gaactgaccg aaaagaaaaa agaaattacc gatgatgact
     6421 tgatttctct tattttagaa gaaaaagtga cagacaaaaa aatcggctat gaatttttgt
     6481 ctctgcaagt gcattacggg acgtctcagg tgccgactgc aacagtctct ttaaaaaatc
     6541 aggaaaacga acagctgatg caagaggcgg caacgggggc gggcagcgta gaagccgttt
     6601 ataatacgct cgggcgctgc atcgataaaa atattgaact gacagactac cgcatccaat
     6661 ccaaccggaa aggcgaagac gcgctggctc aagtttacgt cagagtgacc gtgaacggaa
     6721 aagaaacatc agggcgggga atcgcgcagg atgttctgga agcttctgct aaagcttatc
     6781 tgaacgccgt gaaccggcag ctggtgctgg attgcaattt agacggatta aagagacaga
     6841 ctgcggtcgg ctcgtaatag aaaggagaac gtttgatttg aaaaaacgca ttgctttgct
     6901 gcccggtgac ggaatcggac cggaagtggc ggaatcagcg gcagatgtat tgaaaagcgt
     6961 tgccgaacaa ttcggacatg aatttgaatt tgaaaacggg ctgatcgggg gagcggctat
     7021 tgacgcccat caaaaccccc ttcctgagga gacggtggct ctttgtgaaa gatccgacgc
     7081 catcctgctc ggggcagtcg gcgggccgaa atgggaccaa aatcctccgg agctcagacc
     7141 ggaaaaaggc ctgctcggca tcagaaaaaa actcggcctg tttgccaatc tgcgtcccgt
     7201 gaccgtattt gaaagcttgt ctgaggcgtc tccgctgaaa aaagaatata tcagcggcgt
     7261 cgactttgta atcgtcaggg aactgacggg cggtctctat ttcggagaac cgagcagaca
     7321 gtatgtcaat gaagcgggag aaaaggaagc ggtcgatacc cttttttata agaaagaaga
     7381 aatcgcacgc gttgtcagag aagcctttaa gatggctgcc ggcagaaaag gaaaagtgac
     7441 gtccgttgat aaggcgaatg tgctttcttc aagcaggctg tggcgggaaa ccgcaaatga
     7501 aatcgcaaaa gaatttcctg atgtgacgct tgaacatatg cttgtcgata atgccgcgat
     7561 gcagctcatc tacgctccga gccagtttga cgtcatcgta actgagaata tgttcggcga
     7621 tattttaagc gatgaagcct ccatgctgac aggctcgctc ggcatgctgc cgtcagccag
     7681 tttatcaagt tcaggtcttc acttgtttga acccgtgcat ggatctgcgc ctgacatcgc
     7741 cggtaaaggg atggcaaatc cgtttgcggc gattttatca gcggcgatgc ttttgagaac
     7801 atctttcggg cttgaaaacg aagcgcaggc ggtggaaaaa gcggtcgcaa aggtgcttgc
     7861 agatggcagc cgtacacgtg atatcgcccg ggacggccaa tatgccggaa cgcatgacat
     7921 tactgaaaaa gtaaaagccg cattagccgg ctcgaataca aaatctatag tgtgacgctt
     7981 taaagaaagc ggtcttagtt cataggtaga gggaggaaac aaagatgatg cctcgaacaa
     8041 tcatcgaaaa gatttgggat cggcatgttg taaaaagcgg tgaaggaaaa cccgaccttc
     8101 tctatattga tctgcacctc attcatgagg tgacgtctcc tcaggcgttt gaagggttaa
     8161 gacagaaggg gagaaaggtc agacggccgc agaatacatt cgcaacgatg gaccacaata
     8221 ttccgaccgt caaccgtttt gacattaaag atgaagtcgc aaagcgccaa gtaactgcgc
     8281 ttgaacggaa ttgtgaggag tttggcgtcc gtcttgcgga tcttcacagc gcagaccagg
     8341 gaatcgttca cgtagtcggg cctgagcttg gtctgacact tccggggaaa acgatcgttt
     8401 gcggagacag ccatacatcg actcacggtg cattcggggc gcttgccttc ggtatcggca
     8461 caagtgaggt ggagcatgtt ctttccacac agacactatg gcagcagcgg ccgaaaacgc
     8521 ttgaaatccg cgttgacgga acgctccaaa aaggagtgac cgcgaaggat gtcatcttgt
     8581 cggtcatcgg aaaatacggg gtgaaattcg gtaccggata tgtcattgaa tacaccgggg
     8641 aagtattcag aaatatgtct atggacgaac gcatgacggt ctgcaatatg tcaatagaag
     8701 cgggagcacg ggcgggactg atcgctccgg atgacacgac gattgaatat tgtaaaaacc
     8761 gtaaatacgc gccaaaaggc gaggaatttg aaaaagccgc cgcagaatgg aaagcattaa
     8821 aaaccgatcc gggcgccgta tacgatcatt ccatcgtgct agacggcagc gagatttctc
     8881 caatggtaac atggggcgtc aatcccggta tggttcttcc ggtcgatgcc caaataccgg
     8941 cgccggaaac gattgattct gaagacggta aaaaagaagc catccgcgcg tacgaataca
     9001 tgggaatctc accgaatcaa aaaattgaag atattaaagt cgagcatgtg tttatcggct
     9061 cctgtacaaa ttcgcggatg accgatcttc gccaggctgc ggatatgatc aaaggccgaa
     9121 aagtcgctga cagcgtcaga gccattgtgg tcccgggttc tcaaagcgtg aaacagcagg
     9181 ccgaagaaga agggctgcac cgcgtgtttc tcgaggccgg atttgaatgg agagaatcag
     9241 gctgcagcat gtgcctcagt atgaacaatg atgtcgtgcc tgaaggggaa cgatgcgctt
     9301 ccacttccaa ccgcaacttc gaaggcagac agggaaaagg cgcgagaaca caccttgtca
     9361 gtccggcgat ggcggcaatg gcggccattc acgggcattt cgtcgatgta agaaagtttt
     9421 atcaagaaaa aacagttgtg taaggagtgc gcgaaaagat ggaaccttta aaaacgcata
     9481 cgggaaaagc ggccgtctta aaccggatca acgtcgatac ggaccagatt attccgaaac
     9541 agtttttgaa aagaattgaa agaacaggat acggcagatt cgcgtttttt gattggagat
     9601 accttgagaa cggtgagcct gatcctgaat ttgaattaaa ccgcaaagtc tatgaaggcg
     9661 cgtccatatt aattgccgga gagaatttcg gctgcggatc atcccgtgag cacgctcctt
     9721 gggcgctgga tgattacggc ttcaaaatca tcattgctcc gtcatttgcc gatatttttc
     9781 atcaaaactg ttttaaaaac ggtatgcttc ccatccgtat gccgtatgat cagtggaaaa
     9841 aactcgccgg tcaatatgaa aatcagtctc ttaacatgat ggttgatttg gaaaaccagc
     9901 tcattcacga cagtgaagga aaagagattt catttgaagt cgatcctcac tggaaggaaa
     9961 tgctgataaa cggctatgat gaaatttcat taacgcttct gctggaggac gacattcagc
    10021 agtttgaatc gaaaagaagt tcatggcttc aagcctgaaa aaagccgccc ggatctgtcc
    10081 ggcggctttt tttaccgtgc gcaccatcct ttcttgtgtt tcatgacgcg tgttgataca
    10141 cttgaaaaaa atagcgcctg aaaggaaata aagtatgacg catgacaaga aaaaagctga
    10201 tatcattcct ttcccccgtc tgaaagaacg cttggttgat aaagggatgg ccgccatgaa
    10261 ggataaacag tatcaggagg ccctcgaact gttctcagag gcggtaagcc acggcgatac
    10321 cgagtccgac gtacatttag gcatggcgat ttgttttctg gaactcgggg aattggaaga
    10381 agcaaaacaa gtttgcgaga aaatgctgaa tgaagggtac ggccattatt tcaccgtact
    10441 gcaggtgtac atgaccattt taattcagct gaaacaatat gaagaagtca aaagcacaat
    10501 tgaagctgtg ctggaagaaa accagctgcc cgcagaaagt gcggagcaat tctaccggct
    10561 gctcgaattc agccgcaaaa tgaccgatcc cgaccagcag gatgaagcgt gggaggagga
    10621 atacgaggac attcttgatg cggaaaaagt gctgaacagc cccgctgaac aaatgaatct
    10681 gattcattct ctcaaagacc gcaatattgc aaaatacacg ggtctcttaa aaacgattct
    10741 tcaagatcca ggcgcgcatc ctcttatcaa gacgatgatt ttgacgctga tggcggagca
    10801 tgactacagc aagccggtcc atattacaaa attcggcgat tcaatgaccg cggttccgag
    10861 tgaaacggtt cagcctgatg cggctccgat tttgcatcgc gttctccggg tgcttgatga
    10921 aacgctcggc aatgaaaacc ctacattata cgctgccgta gaggagctgt ggagaaggca
    10981 tctgtacgtc ctgcaccctt ttatgccgaa gtttttgaac gcagatttat gggcggcggc
    11041 gcttcataag gtcggttacg agatgcacgg cattgacatt gagcaggagg aacttcatat
    11101 gatgtacgag tttgacagcc gcgaactcga agaagcctgc acgatgatta aggatattga
    11161 agaaatttct tatttgtaaa tcacaccata tagttgaaag cggtaggcgt tatgttataa
    11221 tatagtggtt gtatttatgt atagcggttt aactgaaatg agaattacgg ttggacaggc
    11281 tgccagttca ttacataatg attctgattc aaagcggttt tttctttgac aaagccgcgg
    11341 attgctttag aatggaagac cgacacaacc tgaatagatt tttggaggga aacacatgtc
    11401 tgtaaaatgg gaaaaacaag aaggcaacga aggcgtatta acggttgaag ttgatgcgga
    11461 tacgttcaaa acagctcttg atgatgcatt taaaaaagta gtaaaacagg tttctattcc
    11521 tggattccgc aaagggaaag ttccccgcgg tttattcgaa cagcgtttcg gcgttgaagc
    11581 tctttaccag gatgctttag atattttact tcctgtagaa taccctaaag cggttgaaga
    11641 agccggcatt gagcctgtag accgccctga aatcgatgtt gaaaaaatcg aaaaaggcga
    11701 aagcttgatt ttcactgcaa aagtgactgt aaaaccggaa gtgaaacttg gcgactacaa
    11761 aggcttagga atcgaaaaag atgacactgc cgttactgac gaagatgtac aaaacgaact
    11821 taaagcgctt caagagcgtc aggctgagct tgtcgtgaaa gaagaaggcg ctgttgaaaa
    11881 cggcgataca gtcgttcttg acttcgaagg tttcgttgac ggcgaagcgt ttgaaggcgg
    11941 aaaagctgag aactactcac ttgaagtagg atcaggttca ttcatcccgg gcttcgaaga
    12001 gcagttaaca ggccttgaag caggcgctga aaaggatgtt gaagtaacat tccctgaaga
    12061 gtaccacgct gaagagcttg ccggaaaacc agctattttc aaagtgaaaa ttcatgaaat
    12121 caaagcgaaa gagcttcctg agcttaacga cgaattcgca aaagacattg acgaagaagt
    12181 tgaaacgctt gctgaattaa ctgagaaaac aaaaaaacgc cttgaagaag caaaagaaaa
    12241 cgaagctgac gctaaattgc gtgaagagct tgttctgaaa gcatctgaaa acgctgaagc
    12301 tgatgttcct caagcgatga tcgacactga gcttgaccgc atgctgaaag aattcgaaca
    12361 gcgtctgcaa atgcaaggca tgaaccttga gctttacact caattctcag gccaagacga
    12421 aaacgcgtta aaagagcaaa tgaaagaaga tgccgcaaaa cgcgtaaaat caaacctgac
    12481 tcttgaagcg atcgctcaag cagaaaacct tgaagtaacg gacgaagaag ttgaagctga
    12541 gctgactaaa atggctgaag cttacaacat gccggttgaa aacattaagc aggcaatcgg
    12601 ttcaactgac gcgatgaaag aagatttaaa agttcgaaaa gcaattgatt ttcttgtaga
    12661 aaaccgttaa tatggttcat aataatagac ataataaaac agggcgcgat taattcgtgc
    12721 cttgttttgt acaattatga tataactctt tttcttgggg caagatagtc attgccgggc
    12781 tgtttttcgt catacatata gaatgtgcaa gtgcgaaaca cattgttacc gtcttactgg
    12841 aaagtatggt aaaatgcaat acatactcga tcgtagcaag aaccgttttc ttttgccctt
    12901 caggtaaaag aaaaagtgag acaagattaa ggggtgaaag aatgtttaaa ttcaacgagg
    12961 aaaaaggaca attgaaatgc tcgttctgcg gaaaaacgca agatcaggtt cgtaagctgg
    13021 ttgcaggacc gggtgtatat atatgcgacg aatgtattga gctctgtaca gaaatcgtag
    13081 aggaagagct tggtacagaa gaagaagtcg aatttaaaga cgttccgaag ccgcaggaaa
    13141 tccgtgagat tctgaatgaa tatgtcatcg gacaggatca ggcgaagaaa tcacttgcgg
    13201 ttgcggtata caaccattac aaacgcatca actccaacag taaagtggat gatgtcgagc
    13261 tttctaaaag taatatttct ttaatcggac cgactggaag cgggaaaaca cttcttgccc
    13321 agacgcttgc gcgtattctg aacgtgccgt ttgcgatcgc ggatgctaca tctctgactg
    13381 aagccggata tgtcggtgag gacgtagaaa acatcctcct caagctgatt caggcagcag
    13441 actatgatgt ggaaaaagca gaaaaaggta ttatttatat cgatgaaatc gataaagtag
    13501 cgcgaaaatc tgaaaacccg tccattacac gtgacgtatc aggcgaaggc gttcagcagg
    13561 cgctgctgaa aattcttgaa ggaacggttg caagcgtgcc gcctcaagga ggacgcaaac
    13621 atcctcatca ggaattcatc cagatcgata cgacgaacat tctgttcatt tgcggcggtg
    13681 catttgacgg cattgaacaa atcatcaaac gccgtctcgg acaaaaagtc atcggcttcg
    13741 gctctgataa taaagcggca gacctggaaa aagaagaact gctttctaaa gttcttcctg
    13801 aagacttgct ccgtttcggt ctgattcctg aattcatcgg ccgtcttcct gtcattgcaa
    13861 gccttgagca gcttgacgaa acggcactgg ttgaaattct gactaaaccg aaaaacgcac
    13921 tcgtcaaaca atacaagaaa atgttagaac ttgatgatgt cgagcttgaa tttgaagacg
    13981 aggcattatc tgaaattgcg aaaaaagcga tcgagcgtaa aacaggcgca cgcggcctgc
    14041 gttctatcat tgaaggcatc atgcttgacg tcatgtttga tctgccgtcc cgcgatgata
    14101 ttgaaaaatg tgtcattacc ggagcgacag tcgcagacgg tgaagcaccg cgtcttgtat
    14161 taaaagacgg cacagttgtc ggccaagata aaacatcagc ataacatgac aaaacctcct
    14221 gactcgaatt gatcaggagg tttttttctt gtcctgaccc ttctgaaaat gtttattccg
    14281 ggctttgctg ggagatacta gcggacagag gaatgaattg gatacataaa tcgttttttc
    14341 aggagggacc agcatgagtt ggacagggat cgcattattt gtacagctgt ttttcgggat
    14401 agtcatcgga ttatattttt ggaatctgct caaaaaccag cgtacacaaa aagtgacgat
    14461 agataaagaa tcaaaaaaag aaatggaaca gctgcgcaaa atgcgcgcca tcagtttatc
    14521 agaaccttta tcagaaaagg tgcggccaaa aagctttcag gacattgtcg gccaggaaga
    14581 cggaattaaa gcgttaaaag cagcgctttg cggaccgaac ccgcagcacg tcattattta
    14641 cggtcctccg ggagtcggta aaacggctgc ggcgcggctg gtattggaag aagcgaaaaa
    14701 acataaacag tcaccgtttc aaaagcaggc tgtatttgtt gaacttgatg cgacgaccgc
    14761 gcgatttgat gaacggggga ttgccgatcc gcttatcggt tcagtgcatg atccgattta
    14821 tcagggagcg ggtgcgatgg gccaagcagg cattccgcag ccgaaacagg gggctgtgac
    14881 ccatgctcac ggcggggtat tgtttattga tgaaatcggc gagcttcacc cgattcagat
    14941 gaataaaatg ctgaaggtgc ttgaagatcg aaaagtattt ttagacagtg cgtattacag
    15001 tgaagaaaat acgcaaatac cgaatcacat tcatgatatt tttcaaaatg ggcttccggc
    15061 agatttccgt ttgatcggag cgacaacgag aatgccgaat gaaattccgc cggccatccg
    15121 ttcgcgctgt cttgaagtat ttttccgcga gctggaaaag gatgaactta aaatcgttgc
    15181 gaaaaaagca gccgacaaaa ttcagaaaga gatttctgac gaagctctca gtgtgctgac
    15241 cacatatacg agaaacggac gtgaagccgt caatatgatc cagatcgccg ccggcatggc
    15301 ggtgactgag gaca
//
