LOCUS       c00035_gnlPro..        15966 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JECGIADN_35.
ACCESSION   c00035_gnlPro..
VERSION     c00035_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-05-01 00:05:22
            Original ID  :: gnl|Prokka|JECGIADN_35
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 5990
            Orig. end    :: 21956
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15966
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[15990:21834]"
                     /cutoff="10000"
                     /detection_rule="(Nitr_red_bet_C and Nitrate_red_del and
                     Nitrate_red_gam and Molybdopterin and minimum(2, [Fer4_11,
                     Molybdopterin, Molydop_binding, Nitr_red_alph_N]))"
                     /neighbourhood="10000"
                     /product="Nitrate_reductase"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..15844
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Nitr_red_bet_C and Nitrate_red_del and
                     Nitrate_red_gam and Molybdopterin and minimum(2, [Fer4_11,
                     Molybdopterin, Molydop_binding, Nitr_red_alph_N]))"
                     /neighbourhood="10000"
                     /product="Nitrate_reductase"
                     /protocluster_number="1"
     cand_cluster    1..15966
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Nitr_red_bet_C and Nitrate_red_del and
                     Nitrate_red_gam and Molybdopterin and minimum(2, [Fer4_11,
                     Molybdopterin, Molydop_binding, Nitr_red_alph_N]))"
                     /kind="single"
                     /product="Nitrate_reductase"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15966
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Nitrate_reductase"
                     /region_number="1"
                     /rules="(Nitr_red_bet_C and Nitrate_red_del and
                     Nitrate_red_gam and Molybdopterin and minimum(2, [Fer4_11,
                     Molybdopterin, Molydop_binding, Nitr_red_alph_N]))"
                     /tool="gutsmash"
     CDS             complement(1094..1999)
                     /locus_tag="ctg35_10"
                     /transl_table=11
                     /translation="VNLTPDERLADALTTIIYQYPPMVREMININAGEKERLLRLSIFE
                     AFSHLSERDLTIDQITAAQLPELLALATHLNPPSFQPNNLTPGEFASQKAYSYVASYLM
                     NRFVHSLSTVGNPPQVLEELITDAGDVMLAQVRRLQFNYNQQFKVADYLADVKARWGLL
                     GAMTAKQSAVLSGAGNEIVSLAGQIGQAFGTASYITHEFQQLSNDPNLFIKMITAGQYP
                     LALLFARQQDPQWFNNFFSSNHRPSQEIFNQAYNLVLSRTDDVKQLITDIFSQLILDIE
                     VLPTGQTQDELLKLVEELKK"
     CDS             complement(2004..2972)
                     /locus_tag="ctg35_11"
                     /transl_table=11
                     /translation="MDIQDKLKRDYENKSIYTAGFYADPDNDLANRKKLFDVLKSLVEN
                     QEATTPFALQIMLTNGEINVMPLGLVDLDELKKYENEQRSKHGLDEHNDDIPLLIQYAP
                     HAEKKEVVKKRIGTVQDLFTNFNEQIEKIWQTIKKFMQDNFALLTTIEKDLIADSQNVM
                     QEYRITFSKMTEAERKEKLGFSVPENEINQFCRYMADMHEVQAVVLSAGAFVNHELLGK
                     NSFTEMISDNIRRSTLFWVLDNTFYEIYYYFYMSNANDKLHKRLKHQRETFIVNMRNDA
                     FHRAQEFTEKQTKKVDFNEYFSDIFIPVAEQIIAEVNKFKD"
     CDS             complement(2978..3250)
                     /locus_tag="ctg35_12"
                     /transl_table=11
                     /translation="MATNLSREDELRGILSDVARKHFTNSRQVNPVSNLFLTTKYAVEN
                     QYISGAVIDESFSSTLAEINLKNAVLTDRGRNKLAQLLTQSAKEN"
     CDS             complement(3346..3999)
                     /locus_tag="ctg35_13"
                     /transl_table=11
                     /translation="MYNVLVADDHAIVRSGISYLVDLQPNFTVVDGTASGTDTYIRVEQ
                     GGIDILIMDLSMPPGENGLITTRRIHDKFPKVKIIILSMHEEQEYINKAMANGAMSYIL
                     KSSPDSEIVNALKHVINGEKYLDANIIVSKKDIKEINASGNTLKLKGYNGLSKREKEVF
                     PLIALGYSNKEISQKMFISTKTVEAHKANISRKLHLHGRVELVQYAIHHHLIDL"
     CDS             complement(3992..5047)
                     /locus_tag="ctg35_14"
                     /transl_table=11
                     /translation="VLETANWIQKYFNQSPDAIFLFKNDDLLVSNEPAQRLVTMLNLDV
                     NYLLQIGKDAWSQLENDDCASCLIKKRLKGAAVPITFHSNATHPFHFSMVYRPLDDKEN
                     VFALTLENREQQQRLSQVEEQRILNQYVNEAHEKERQKISQDLHDSVAQGIYAAIMGIQ
                     RLATVQNQRNTEQFQSMSAAIEKQLQTTLKEIKELALDIRPSVLDNFGLIPAIKALAKR
                     LQNSTGITINVIALTSAENLQKNIQNVLYRITQEAINNAIKHAHSTEITIIVTNHNSYL
                     QLEILDNGIGFDLEQHSRFNGHSLGLMNMNERVKAYNGAFTITSKINKGTTVKVKFPYN
                     NLNKDTVRTNV"
     CDS             complement(5198..5482)
                     /locus_tag="ctg35_15"
                     /transl_table=11
                     /translation="MKSKDSMTNPDFQKLISLVLNDLTIRRTMLENREQEVNQQMSSLE
                     KDAELEQLDDQIQQIQADFDHYREFQDPEFDFSATKYFQGPSMGLPRHP"
     CDS             complement(5472..6044)
                     /locus_tag="ctg35_16"
                     /transl_table=11
                     /translation="MIGLVYAGGKSIRFGKDKATYHVPRLPATNVQLAVEKLMPLCQQI
                     IVCANETNRAHIIELVGQVPAVQIICDIPPYDHHGPLSAIIACTSQFSVVQDYLTLAVD
                     YPYITKDVLAILARTSNSYIVTSQHSHYSLAHFSISNEQVTTWVDNNSDWRLRSFITNK
                     CGCHPLAYRSSAEFSNLNYREVDLNEK"
     CDS             complement(6044..6532)
                     /locus_tag="ctg35_17"
                     /transl_table=11
                     /translation="MAITLQIIGHKKSGKTLIMTALIERLSKEGYRVAALKHDAHNAAM
                     DVPTTDSARMSNAGANQVILQSATEFFFHQKSNVPTLTEMVELLSDDNDFVLIEGHKEA
                     NQYPQILLLKPGEDPTNIAPTTPLKTGSIFSGTNADLLGKNTIVNWCYNYLKQIKENT"
     CDS             complement(6511..7728)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MoCF_biosynth"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MoeA_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MoeA_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg35_18"
                     /sec_met_domain="MoCF_biosynth (E-value: 4.8e-23, bitscore:
                     72.2, seeds: 114, tool: rule-based-clusters)"
                     /sec_met_domain="MoeA_C (E-value: 1.6e-13, bitscore: 41.5,
                     seeds: 41, tool: rule-based-clusters)"
                     /sec_met_domain="MoeA_N (E-value: 1.3e-39, bitscore: 126.2,
                     seeds: 1302, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTRRTPISVAEAQKKINEIPLKTTTETIPLSEANHRILAEDVHA
                     HYDYPHFRRAGMDGYAILASDDHDFPREFNVRGEIQAGATWDQPLQPGDAVRIMTGAYV
                     PSDAGKVIRIEKTRPAEDKNKVQIITTESKTNITETGTDVKSGDIVLAKDQEINPGGLA
                     VLTAFGVQEVTVYKKPRIAIIATGTELLGPNETIEQGKIFNSNGIMLKNLVEETGGIVD
                     FETQLPDDANLIKQTLEEQIATHEIVITDGGVSVGDFDFIGDEARKADELLFNKIKQRP
                     GSVTTAFVQNNTLVMALSGNPGACFTGFYLYMEPLIRRYQHQASRIKRVRAILAAPYNK
                     TNGFDRYLRCTYEFKDDQFYVYPNGINRSGSLANLQTTTCLALIPHSTTPMKVGTETDA
                     WLLPFK"
     CDS             complement(7718..8215)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MoCF_biosynth"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg35_19"
                     /sec_met_domain="MoCF_biosynth (E-value: 6.7e-34, bitscore:
                     107.4, seeds: 114, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIAILTVSDSRTLDSDTSGKLIAMKMANAGLSVVDRVIVNDDI
                     VNIQTAYLQLEQQAIDIIITNGGTGVAQRDVTIPAIRPLLKRLIPGFGEAFRQISFDEI
                     GTRALASQALAGFNYRNQLTYCLPGSQNACQTALNKLILPEYEHLLFESSSQRKEVHHH
                     AH"
     CDS             complement(8212..9231)
                     /locus_tag="ctg35_20"
                     /transl_table=11
                     /translation="MNRYDRQERVHQIGVVGQQKISHATIMIVGVGALGSYTAEQLVRA
                     GVKRLVLIDPDTVDVTNLQRQSLFTEADANQQRLKVEAAKEHLHEINSACQITAIPAPI
                     TADLIDEYQFTFCLDCLDNYQARDLLNKLAIIKNFDYLFASCAGTYGNVMAISPQNHPC
                     LNCLFPNINELKQNDCDLIGVNTALIPIVAGLQVSLALHYLVDKTQVNFNELITVDNWS
                     MQFSKFAINKNCHCPACAKPSSISLEEESAPELHMLCGENAYYTVKEKPINFGRLKEFL
                     AKKELLINANRLFLHFKWENRPVSIFKNGKIVMYDLPTSAIAQKQFESLNTLMKEDLL"
     CDS             9414..9758
                     /locus_tag="ctg35_21"
                     /transl_table=11
                     /translation="MEPLHNLKKIVVVGKSFIVSDGRMTKLSEQLMESTVQAHVLGMFM
                     SSKELLLGNIKLQIIHHADLIFQDMNHGDVHGELVSLGMNIVPFELSTHIFVVNYGSFG
                     LLPRKNMKIP"
     CDS             10001..13042
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Molybdopterin"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Molydop_binding"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_22"
                     /sec_met_domain="Molybdopterin (E-value: 5.2e-118,
                     bitscore: 385.3, seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="Molydop_binding (E-value: 1.5e-23,
                     bitscore: 73.8, seeds: 74, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSFYDWYADLPPASPQVWGEQTDVPESAEWYNSSYIIMWGSNVPL
                     TRTPDAHFMTEVRYKGTKIVVVSPDYAENVKFADDWLAPEPGSDSAVAQAMTYVILDEF
                     YQKHPVKRFIDYSKRFTDLPFMVELEPSTANDDHYTPGRFVRISDLVDDDTIVNPAWKT
                     VVYDQNNHKIVVPNGTMGQEYNAKEKWNLELLDQNGNKIDPALSINDQGEETEQIIADF
                     PAFSNDGNSVVQRHLPVKKLKFTDGQEHLVTNVYDLMMAQMGINRTGNDELAAKDAMDA
                     ESYFTPAWQESRSGVKAEQVIQIAREFAQNAAENEGRSMVIMGGGVNHWFNADMNYRNI
                     INMLMLCGCVGMTGGGWAHYVGQEKLRPQEGWANITFANDWEKGGARQMQGTTWYYFAT
                     DQWRYEEIDNQAQKSPVWKSKHSYLHNADYNQMAIRLGWLPSYPQFDRNPLSFAKDYNT
                     TDIDEISKKVVDELKKGTLHFAAEDPDANQNQPKAFFLWRSNLFASSGKGAEYFMKHLL
                     GAENGLLAKPNDRVKPQDMVWRDKGAIGKLDLVVDMDFRMVSTPMYSDVVLPAATWYEK
                     KDLSSTDMHPFIHPFNAAVSPMWESKSDWQQFKLLAKTVSEMAKKYMSGTVYDLKSAPL
                     GHNTQGEIAQPYGKIKDWKNGETEPIPGKTMPSLKLVTRDYTKIYDKFITLGPNIVNNY
                     GYKVDDQYDYLKGMNGTASEGIGAGCPLLDEDEKVCDAILRMSTASNGKLADRAWEKKQ
                     ERTGEHLTDIGRGHADDSMSFKQITAQPQEAYPTPIGTSAKHGGARYTPFSLMTERNIP
                     TFTLTGRQHFYIDHEIFREFGENMATYKPSLPPVVMAPGDVDVPPVKDEVTLKYMTPHG
                     KWNIHTMYYDNLEMLTLFRGGPTIWISPQDADKIKVKDNDWIEVYNRNGVVTARAVVSV
                     RMPEGSMYMYHAQDNEIYEPLSTITGNRGGSHNAPTQIHVKPTHMVGGYGQLSYGWNYY
                     GPTGNQRDLYANVRKLKKVNWSED"
     CDS             13032..14591
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Fer4_11"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Nitr_red_bet_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_23"
                     /sec_met_domain="Fer4_11 (E-value: 5.1e-39, bitscore:
                     123.3, seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.0008, bitscore: 10.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="Nitr_red_bet_C (E-value: 2.5e-28,
                     bitscore: 88.4, seeds: 110, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKIKAQISMVLNLDKCIGCHTCSVTCKNTWTNRPGAEYMWFNNVE
                     TKPGVGYPKRWEDEDQYHGGWTLNSKGKLKLRAGSKLNKIALGKIFYNNDMPELDNYYE
                     PWTYDYKTLFGPEQKHQPVARPKSQITGEGMELTTGPNWDDDLAGSTEYVQQDPNMQKI
                     EGDIKNNFEQAFMMYLPRLCEHCLNAPCVASCPSGAMYKRDEDGIVLVDQERCRGWRFC
                     MTGCPYKKVYFNWKTHKAEKCTFCYPRIEEGQPTVCAETCVGRIRYIGAILYDADRVEE
                     AASTPDESKLYEAQLGLFLDPNDPKVVKQALKDGISEEMIEAAQKSPIYKMAVKEKIAF
                     PLHPEYRTMPMVWYIPPLSPVMSYFEGRDSIKNPEMIFPGIDQMRVPVQYLASLLTAGN
                     VPVIKKALYKLAMMRLYMRAKTSGRDFDSSKLERVDLTEERATSLYRLLAIAKYEDRFV
                     IPSSQKAEMEDAQTEQGSLGYDECEGCALAPQHKSMFKKAEAGKSTNQIYADSFYGGIW
                     RD"
     CDS             14584..15162
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Nitrate_red_del"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_24"
                     /sec_met_domain="Nitrate_red_del (E-value: 2.1e-09,
                     bitscore: 28.2, seeds: 108, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VIDFRRLTDLKDTFAVLSRLIDYPDTETFSPEIRQLLLTDNALST
                     ATRGELLSLFDELAALSSIEVQEMYAHLFEMNRRYTLYMSYYKMTDSRERGTILARLKM
                     LYEMFGISEATSELSDYLPLLLEFLAYGDYTNDPRRQDIQLALSVIEDGTYTLLKNAVT
                     DSDNPYIQLIRLTRSLIGSCIKMEVREDA"
     CDS             15155..15844
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Nitrate_red_gam"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_25"
                     /sec_met_domain="Nitrate_red_gam (E-value: 1.9e-77,
                     bitscore: 250.4, seeds: 140, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHNGWSIFLWVIYPYIMLASFFIGTFVRFKYFHPSITAKSSELFE
                     KKWLMIGSVTFHIGIILAFFGHCLGMFIPASWTAYFGITEHMYHIFGSLMMGIPAGILA
                     FVGIAILTYRRMTCSRVYKTSDINDIIVDWALLITIALGLACTITGAFIDYNYRTTISP
                     WARSLFVLNPQWQLMRSVPLIYKIHVLCGLAIFGYFPYTRLVHALTLPWQYIFRRFIVY
                     RRRARVY"
ORIGIN
        1 aacgttatta ttagcaacgc ctgtcctttt ggggtcaatt atgcgaattc cagtggggat
       61 cttaagtgat cgttatggtg ggaaaaaggt ctatttgatt ttgatggctt ttattttgat
      121 tccactaatt atgattccac atgtccattc attcgggatg ttgctctttg ctgcattgct
      181 cgttgggatg tcaggaacat catttgctgt tggagtttct tatgcttcag tttggttccc
      241 gccagaacag cagggactag ctcttgggat tgtctcaatg ggaaacatgg ggaatgctgt
      301 agctgcaatg actttaccgt atatttctaa ggcggcggga tttgatagtg tttattactt
      361 cttgattatt cttacagtga tctttggtgt tctctttgca gttttttgta aggaaatgcc
      421 agttgataaa agcaagacga taaagggagc attatctgtt gccacagaca gtggaacatg
      481 gtacctatca ctgttctatt tccttacatt cggtttattc gttgccttta caaatttaac
      541 gccgacattc ttaactggga tgttccatta tactcctgtt acagcaggtc tttattcggc
      601 cttatttgcc tttgtatgta cgttagttcg gccatttggt ggttaccttg ccgataggaa
      661 acgaccgatg gcattattac aatgggtctt tgtagcaatc gttatctttg ctatttggat
      721 tatgcttagt ttccacaatc aattcatgtt tatcgcagga attgttttgg ttggtctttc
      781 tgccggaata ggtaacgggg ttgtctttaa aatggttccg tatgtatccc aaggtaatac
      841 aggagcagtt actggttttg ttggagctgt tggtggcctg gggggattct tcccaccact
      901 aattattggt tatatttacc aatggacagg tagttatgag cttggaattg cgcttttagc
      961 gctaaccagt gcaatttgct ggtttgctct atggaaacat tatattcatg gtgacgttca
     1021 tatcgttaaa taagcacatt aaaaaatgga gatgaggata atttcttcct taatctccat
     1081 ttttagtttt aaattatttt tttaattctt caactagttt aagcaattca tcctgagttt
     1141 gaccagtcgg taatacttca atatcaagga ttaactggga gaagatatcg gtgatcagtt
     1201 gtttgacatc atcagtgcgg ctaagcacta agttataagc ttggttaaat atctcttgtg
     1261 aaggacgatg atttgaagag aaaaaattat taaaccattg tggatcttgt tgacgagcga
     1321 ataaaagtgc cagtggatac tgcccagccg ttatcatctt tataaacaag ttgggatcat
     1381 tgctaagctg ttgaaactca tgtgtaatat aactagcagt accaaaggct tgaccaatct
     1441 gtcctgcaag cgagacaatt tcatttcctg ctccactaag gacggcactt tgttttgcgg
     1501 tcattgctcc aagtaatccc caccgtgctt taacatctgc taaataatca gctaccttaa
     1561 attgctgatt atagttaaac tgcagtcgtc gaacctgtgc aagcatcaca tccccagcgt
     1621 cagttatcaa ctcttcaagt acctgtgggg gattacctac agtacttaac gaatggacaa
     1681 agcgattcat caaatagctc gcaacatatg aatatgcctt ttgactagcg aattccccag
     1741 gagttaggtt atttggttga aaagaaggag gattcaaatg agttgctaat gccaatagtt
     1801 ccggtaattg agcagctgtg atttgatcaa tcgtaagatc tctttcgctg aggtgactga
     1861 aagcttcaaa aatcgataat cttagcagac gttctttttc accggcatta atattaatca
     1921 tttcacgaac cattggagga tattgataaa taatggttgt taatgcatct gccagccgtt
     1981 catctggtgt taaattcaca gtatcagtcc ttaaatttat ttacttcagc aattatttgt
     2041 tcagcaacgg ggatgaagat atcactgaag tattcattaa aatcaacctt ttttgtttgc
     2101 ttttcagtaa attcttgtgc acggtgaaaa gcatcattac gcatattaac gataaaggtt
     2161 tctcgttgat gtttaagtcg tttatgaagc ttatcattgg cattgctcat gtagaagtag
     2221 tagtaaattt cgtagaaggt attatcaaga acccagaaga gggtactccg tcgaatgtta
     2281 tcgcttatca tctcagtaaa ggaattttta ccaagaagtt catggttaac gaaagcacca
     2341 gcagataata cgactgcttg tacttcatgc atatcagcca tgtaacggca aaattggttg
     2401 atttcatttt ccggaacact aaaccccagc ttttcttttc gttcagcctc agtcatcttg
     2461 gaaaaagtaa tccgatattc ttgcatcaca ttttgactat cagcaatcaa atccttttcg
     2521 atagtcgtta ataaagcaaa attatcctgc ataaatttct taatagtttg ccatattttt
     2581 tcaatttgct cgttaaagtt tgtaaaaaga tcttgaactg tacctattct ttttttaacc
     2641 acttcttttt tctctgcatg aggggcatat tggattagaa gaggaatatc atcgttatgt
     2701 tcatctaaac catgcttaga tcgttgttca ttttcatatt ttttaagttc atcaagatca
     2761 acgaggccga ggggcattac attaatttcg ccatttgtaa gcatgatttg taaagcaaat
     2821 ggcgttgtgg cttcttgatt ctcaactagt gattttaaga catcaaataa ttttttacga
     2881 tttgcaaggt cattatctgg gtctgcgtaa aagcctgcag tatagatcga tttattttcg
     2941 taatctcgtt ttagcttatc ttgaatatcc atcttaatta attctccttt gctgattggg
     3001 tgagaagttg tgcaagctta ttacgaccgc gatcagttaa aacagcattt tttaaattta
     3061 tctctgctaa tgttgaacta aatgattcgt caataactgc tccagaaata tattggtttt
     3121 caactgcata tttagttgtt aaaaacaggt tggaaacggg attaacttgt cgactattag
     3181 taaagtgttt gcgagcaaca tcactgagga ttccccgcaa ctcatcctct cgactgaggt
     3241 tcgtcgccat tataaatcca ctcctttaat cgtatttctt ttattgtaaa aaaatatcga
     3301 agtaaataaa atcggggatt cttcttaatt cagaatcccc gctagttaaa ggtcaattaa
     3361 atggtgatga atagcatatt gtactagttc aacccgtcca tgtaaatgaa gtttgcgtga
     3421 aatatttgct ttatgtgctt ctactgtctt tgttgaaata aacatctttt gggagatttc
     3481 tttatttgaa taccctaaag caataagtgg aaagacttct ttttctcttt tagagagacc
     3541 attatagccc tttaatttta aggtattacc agaagcattt atttccttaa tgtctttctt
     3601 actaacaatg atgtttgcat caaggtattt ttcaccattt ataacatgtt taagggcgtt
     3661 aacaatttcg ctatccggtg aactcttcaa aatataagac attgcgccat ttgccattgc
     3721 cttattgata tactcctgtt cttcgtgcat cgagagaatg ataattttaa cttttggaaa
     3781 cttgtcatgg attcgccgag tcgtaatcag accattttcg ccagggggca tacttaaatc
     3841 cataattaaa atgtcaattc caccttgttc aactcgaata tatgtatctg ttccactcgc
     3901 tgtcccatca accaccgtaa aattcggttg aagatcgact aaatatgaaa ttcctgaacg
     3961 aacgattgcg tggtcgtctg caactaaaac gttatacatt tgttctcacc gtatccttat
     4021 ttaaattatt atagggaaac ttcaccttga ctgtcgttcc cttattaatt tttgatgtaa
     4081 ttgtaaaggc cccattatat gccttaacgc gttcattcat attcattaat ccaagtgaat
     4141 gcccattaaa tctgctatgc tgttcaagat caaagccgat accattatca aggatctcta
     4201 actgaaggta actattatgg ttggtaacaa taatagttat ttctgttgaa tgagcatgct
     4261 taattgcgtt attaattgcc tcttgtgtaa ttcggtaaag aacgttttga atattttttt
     4321 gcaggttttc ggcagaggta agggctataa cattaatcgt gattcctgta ctattttgaa
     4381 gccgttttgc caaagctttg attgctggaa ttaagccaaa attatcgagc accgagggac
     4441 gaatatcgag tgcgagctct ttaatctctt taagggtcgt ttgtaactgc ttttcgattg
     4501 cagcactcat tgattgaaac tgctcagtgt ttctttgatt ttgaaccgtt gctaatcttt
     4561 gaatgcccat tattgccgcg tagattccct gcgcaacact atcgtgaaga tcttgtgaga
     4621 ttttttgccg ttccttttca tgcgcttcat tgacatattg attgagaatt cgttgctcct
     4681 caacttgaga aaggcgctgc tgttgctcac gattttcaag agttagggca aagacatttt
     4741 ctttatcatc aagaggacga taaaccattg aaaagtgaaa gggatgagta gcattggaat
     4801 gaaatgttat cggaactgca gctcctttta accgcttttt aatcagacat gacgcacagt
     4861 catcattttc cagttgtgac caagcgtcct ttccaatttg taataggtaa ttgacatcta
     4921 aattaagcat agtaactaac cgttgtgccg gctcattact aactaaaaga tcatcatttt
     4981 taaataagaa gattgcatct ggtgattgat taaaatattt ttgtatccaa ttagctgttt
     5041 caagcacgat ctgcttcctc ctaaataaaa ttccccaatc gctatcataa tattcctatt
     5101 ttatatatta acgctttctt tggttagaag caacgataga caacttaaaa ggcagggcta
     5161 agaaaagctc tgcttcttta gccctgccat ctagctttta aggatgtcgt ggtaacccca
     5221 tcgatggtcc ctggaaatac ttggttgcac taaaatcaaa ttccggatct tggaattcgc
     5281 ggtaatgatc aaaatcagct tgaatttgtt gaatttggtc atccaattgc tccaattcag
     5341 catctttttc cagtgaactc atttgttggt ttacttcttg ttcccgattt tctaacattg
     5401 ttcgtctgat tgttaagtca tttaatacaa gggaaatgag tttttgaaaa tcaggatttg
     5461 tcattgaatc tttacttttc atttaaatcg acctcacgat agtttaaatt tgaaaattcg
     5521 gcacttgagc gatatgcaag gggatgacac ccgcatttat tagtgatgaa actacgtaat
     5581 cgccagtcac tattattatc aacccatgta gtaacttgtt cattgctaat tgaaaaatga
     5641 gctaatgaat aatgactatg ctgacttgtt acaatataag agttggatgt acgagcaaga
     5701 atggcaagta catcttttgt gatatatgga taatcaacag ccaaagttaa atagtcttga
     5761 acaacggaaa attgactagt acaagcaata attgctgaaa ggggaccatg atgatcataa
     5821 ggaggaatat cacagataat ctgcacagcc ggtacctgac caactaattc tattatatgt
     5881 gcacgatttg tttcattagc acaaacaatg atctgctgac aaaggggcat tagtttctca
     5941 actgctagct gtacattggt agctggtaat cttggaacat gataagtagc cttgtcttta
     6001 ccaaagcgaa tagatttgcc gcccgcgtat actaatccaa tcatcaagta ttctccttta
     6061 tttgttttaa gtagttatag caccagttta caattgtatt tttccctagt aagtcagcat
     6121 ttgtcccact aaaaatacta ccggttttaa gcggcgtagt aggagcaata ttagtaggat
     6181 cttcgccagg ctttaataat aaaatttgcg gatattgatt ggcttcctta tggccttcaa
     6241 tcaagacaaa atcattgtcg tcacttaaca actcaaccat ttccgttaaa gttggaacat
     6301 tacttttttg atgaaagaaa aattcagttg cagattgcaa gataacttgg tttgctccag
     6361 cgttactcat tctagcactg tcagtagttg gcacatccat tgcagcatta tgggcatcat
     6421 gtttaagagc agctactcga tatccttctt ttgaaagcct ttcaattaaa gccgtcatga
     6481 taagagtctt cccgcttttc ttatgaccaa ttatttgaag ggtaatagcc atgcatcagt
     6541 ctccgttccg accttcattg gagttgtact atgcggaatc aatgccaaac aggtcgtcgt
     6601 ctggaggtta gctaatgagc cagatcggtt gattccattt ggataaacat aaaattgatc
     6661 atctttgaat tcataagtac aacgaaggta acgatcaaag ccgttagttt tattatatgg
     6721 ggctgctaat attgcccgta ctcgcttaat tcggcttgct tggtgttgat agcgtcgaat
     6781 cagcggttcc atgtagagat aaaagccagt aaaacaagcg cctggatttc cagaaagagc
     6841 cattactaac gtattatttt gaacaaaggc agtcgtaacg cttcctggtc gttgcttaat
     6901 cttattaaac agcaattcat cagctttacg tgcttcatct ccaatgaaat caaaatcacc
     6961 gacagaaacg ccaccatcag taattacaat ttcatgagtt gctatttgtt cttcaagagt
     7021 ctgcttgata agattagcat catctggtaa ttgggtttca aaatcaacaa tcccaccagt
     7081 ttcttctacc agatttttta acataatgcc attactatta aagatctttc cctgttcaat
     7141 tgtctcatta gggcctaata attcagttcc agtggcgata attgcaatcc gtggtttttt
     7201 ataaactgtt acttcttgaa caccaaaagc cgttaagact gctaggccac cgggatttat
     7261 ttcctgatct tttgctaaaa cgatatcacc gctttttaca tcagtaccag tttctgtaat
     7321 gttagtttta ctctcagttg taataatttg aaccttattt ttatcttcag caggacgagt
     7381 tttttcaatt cgaattactt tccccgcatc agaagggaca tatgcaccag tcattatccg
     7441 aactgcatcc cctggctgta atggttgatc ccaagttgct ccagcttgaa tctctcctcg
     7501 gacattaaac tcgcggggga agtcatgatc atcgctggct aaaattgcat acccatccat
     7561 tcctgctcgg cgaaaatgag gatagtcata atgagcatgg acatcctcag ctaaaatacg
     7621 atggttagct tctgataggg gaattgtttc tgtagttgtt ttcaggggga tttcgttaat
     7681 ctttttctgt gcctcggcaa cagagattgg tgttcttcta gtgagcatgg tggtgaactt
     7741 cctttcgttg ggaactgctt tcaaataata aatgttcata ttctggcaaa attagtttgt
     7801 ttagagccgt ttgacaggca ttctgggaac ctggtaaaca ataggtgagc tggttgcggt
     7861 aattaaatcc ggctagggct tgtgatgcaa gggcccgagt accaatttca tcaaaagata
     7921 tctggcgaaa cgcttcccca aaaccaggaa ttaggcgttt gaggagtgga cggatagccg
     7981 gaatagtaac atcacgctga gcaactcctg ttccaccatt agtaatgatg atatcaatag
     8041 cttgttgttc tagttgaagg taggcagttt gaatattgac aatatcatca ttaacgatta
     8101 cccgatcaac tactgatagg cccgcattag ccatcttcat agcaattaat tttccagaag
     8161 tatcgctatc taatgttcga ctatcgctaa ccgttaaaat tgcgattttt ttcataatag
     8221 gtcttctttc attaaagtat ttaatgactc aaactgtttc tgggcaatcg ccgaagtagg
     8281 taagtcatac ataacaatct taccattctt gaatatactt actggacgat tttcccattt
     8341 aaaatgaaga aacaatcgat ttgcgttaat taagagctct tttttagcca aaaattcttt
     8401 aagtctgcca aaattaatag gtttctcttt gactgtataa tatgcatttt ccccacataa
     8461 catatgtaat tctggtgctg attcttcttc taaagaaata ctgctaggct tagcacaggc
     8521 gggacaatgg caatttttat taatagcaaa cttactaaat tgcattgacc aattgtcaac
     8581 agtgatcaat tcattaaaat taacctgtgt tttatcaact agataatgaa gcgctaaaga
     8641 tacctgtagt cccgctacaa taggaattaa agcagtatta accccaatta aatcacaatc
     8701 gttttgtttt aattcattga tattaggaaa aagacagttc aagcaaggat gattttgcgg
     8761 cgaaattgcc attacattcc cataggtacc tgcacaactg gcaaacagat aatcaaaatt
     8821 tttgatgatt gctaatttgt ttaataggtc ccgtgcttga taattatcaa gacagtctaa
     8881 acaaaaggta aactgatatt cgtcaataag gtcagcagta atcggcgctg ggatcgcagt
     8941 aatttgacat gctgaattaa tttcatgtaa atgttcttta gctgcttcga ccttaaggcg
     9001 ttgttggtta gcatctgctt cggtgaaaag cgattgacgt tgaagattag ttacatcaac
     9061 agtgtcagga tcaattaaga caagtctttt aactccagca cggacaagtt gctcagctgt
     9121 ataacttccc aatgctccta caccgacaat cataatagtt gcatggctaa ttttttgctg
     9181 accaacgaca ccaatttgat gtaccctttc ttgacgatcg taacgattca tggctattaa
     9241 cacctcattt agttcgaaaa tataggtatt tccctagtcg tagtatagca gttatggtgc
     9301 taatctttac attagggaaa agacttactt tatttttaat attggtaagc catccaataa
     9361 aggaggtcaa tcaacgatga agtcacggtt ctttaacaag gttgataagt ttaatggaac
     9421 ctttacacaa cttgaagaaa atagtcgtcg ttgggaaaag ctttatcgtc agcgatgggc
     9481 gcatgacaaa gttgtccgaa caactcatgg agtcaactgt acaggctcat gttcttggaa
     9541 tgtttatgtc aagcaaggaa ttattacttg ggaacatcaa gctacagatt atccatcatg
     9601 cggacctaat attccaggat atgaaccacg gggatgtcca cggggagcta gtttctcttg
     9661 gtatgaatat agtcccgttc gaattaagta cccatatatt cgtggtaaat tatgggagct
     9721 ttggactgct gccaagaaag aacatgaaaa tcccttagat gcgtgggcaa gtattgtcga
     9781 agatccagaa aagtctaaaa agtataaaaa ggtccgagga cacggtggct taattcgtgt
     9841 tcatcgttat gaagcattag aaatgatttc agctgcttgc ttatacacaa ttaagaaata
     9901 tggacccgac cgtattggtg gttttacccc aattcctgca atgtcaatga tgagtttcag
     9961 tgccggagcc cgattcatcg ccttaatggg tggggaacaa atgagtttct acgattggta
    10021 tgctgatcta ccgcctgcgt ctccccaagt ttggggtgaa cagactgatg ttccagaatc
    10081 tgcagaatgg tataacagtt cctatattat tatgtgggga tcaaacgttc cattaactcg
    10141 gacaccagat gcacacttca tgacagaagt taggtacaag ggaacaaaga ttgtagtagt
    10201 tagccctgat tatgctgaaa atgtaaaatt cgctgatgac tggcttgcac cagaaccagg
    10261 tagtgattct gctgttgctc aagcgatgac ttatgtaatt ttagatgaat tctaccaaaa
    10321 gcacccagtc aaacgtttca ttgattattc taagcgattt actgatttac cattcatggt
    10381 tgaattggaa ccaagtacag caaatgatga tcactataca ccaggtcgtt ttgttcggat
    10441 tagtgactta gttgatgatg atacgattgt taatccagca tggaagacag tggtttatga
    10501 ccaaaataac cacaaaattg ttgttccaaa tggaacgatg ggtcaggaat ataatgctaa
    10561 agaaaaatgg aatcttgaat tattagacca aaatggcaat aagattgatc cggcactttc
    10621 tattaatgat caaggtgaag aaactgaaca aattattgct gatttccctg catttagtaa
    10681 tgacggaaac agcgttgttc aacggcattt accagttaaa aagctcaaat tcacagatgg
    10741 tcaagaacac ttggttacta atgtttacga cttaatgatg gctcaaatgg gaattaatcg
    10801 gactggtaat gatgaacttg ctgctaaaga tgcaatggat gctgagagtt actttactcc
    10861 tgcttggcaa gaaagccgtt cgggagtaaa agcagagcaa gttattcaaa ttgctcgtga
    10921 atttgcccaa aacgcggccg aaaatgaagg tcgaagtatg gtaatcatgg gtggtggagt
    10981 caaccactgg ttcaatgccg atatgaacta tcgaaatatt attaatatgc tgatgttgtg
    11041 cggttgtgtt ggtatgactg gcggtggttg ggctcactac gttggtcaag aaaagctccg
    11101 tccacaagaa ggttgggcaa acattacttt tgccaatgac tgggaaaaag gtggtgcccg
    11161 tcaaatgcaa ggtactactt ggtattactt tgcaactgat caatggcgtt atgaagaaat
    11221 tgataatcaa gctcaaaagt cacccgtttg gaagagtaaa cactcttact tacataatgc
    11281 tgattataac caaatggcaa ttcgtttagg atggttacca tcatacccac aatttgatcg
    11341 taatccgcta tcttttgcaa aagattacaa tacaactgat attgatgaaa tttcaaagaa
    11401 agttgtcgat gaattgaaga aagggacttt gcattttgct gctgaagatc ctgatgctaa
    11461 ccaaaatcaa cccaaagcct tcttcctatg gcgttcaaac ttatttgcat cttctggcaa
    11521 aggtgctgaa tactttatga aacacttatt aggtgctgaa aacggattgc ttgctaagcc
    11581 aaatgatcga gttaagcccc aagatatggt ttggcgtgac aagggagcaa ttggtaagtt
    11641 agatcttgtt gttgatatgg acttccgcat ggtttcaaca cctatgtact ctgatgttgt
    11701 cttgccagct gctacttggt atgaaaagaa ggacctttca tcaactgata tgcacccatt
    11761 tattcatcca tttaatgcag cagtcagtcc gatgtgggaa tcaaagtctg actggcaaca
    11821 attcaagctc ttagcaaaaa ctgtttctga aatggcaaag aaatacatgt caggaacagt
    11881 ttacgatctt aagagtgcac cacttggcca taatacccag ggagaaattg ctcaaccgta
    11941 cgggaaaatt aaagattgga agaatggtga aactgaacca attccaggaa aaacaatgcc
    12001 ttccttgaaa ttggttactc gtgattacac caagatttac gataaattca ttacccttgg
    12061 acctaatata gtgaataact atggctataa agtcgatgat caatatgatt atttaaaggg
    12121 aatgaatgga actgccagcg aaggcattgg tgcaggctgt ccgttacttg atgaagatga
    12181 aaaagtatgt gatgcaatct tacggatgtc aactgcttcc aatggtaaac tcgctgaccg
    12241 agcctgggaa aagaagcaag agcgaactgg tgaacattta acagatattg gccgtggtca
    12301 tgctgatgat tcaatgtcat ttaagcaaat cactgctcaa ccacaagaag cctatccaac
    12361 accaatcgga acttctgcta aacatggtgg ggctcgatac acaccattct cattaatgac
    12421 tgagcgaaat attcctacat ttactcttac aggtcgtcag catttctaca ttgatcatga
    12481 aattttccgt gaatttggtg aaaatatggc aacttataaa ccatccttac caccagttgt
    12541 aatggcccca ggagatgttg atgttccacc agtaaaagat gaagttacac ttaaatatat
    12601 gactcctcat ggtaaatgga atattcatac gatgtactac gataaccttg aaatgttgac
    12661 attattccgg ggtggtccaa ctatttggat tagtccccaa gatgccgata agattaaggt
    12721 aaaagataac gactggatcg aagtttataa ccgtaatggg gttgttactg cgcgggcggt
    12781 tgtttctgtt cggatgcctg aggggtcaat gtacatgtac cacgcccaag ataatgaaat
    12841 ttatgaacct ctttccacca ttaccggtaa tcgtggggga tcacataatg caccaacgca
    12901 aatccatgtt aagccaacac acatggttgg aggatatggc caattgagtt acggttggaa
    12961 ttattatgga ccaactggaa accaacgtga tctttatgca aatgtaagaa aactgaagaa
    13021 ggtgaactgg agtgaagatt aaagcacaaa tcagcatggt cttaaacctc gataagtgta
    13081 ttggttgtca tacctgttca gtaacttgta agaatacatg gacaaatcgt ccaggcgctg
    13141 aatacatgtg gtttaataat gttgaaacta agccaggtgt cggttatcca aaacgctggg
    13201 aagatgaaga tcaataccat ggagggtgga cccttaattc aaaaggtaaa ttaaaattac
    13261 gtgctggaag caaattaaat aaaatcgctc ttggcaagat tttttacaat aatgatatgc
    13321 cagagttaga taactactac gaaccatgga cttatgatta taagacgtta tttggccctg
    13381 aacaaaagca tcaacctgtt gctcgtccta agtcgcaaat tactggcgaa ggaatggaat
    13441 taaccactgg tcctaactgg gatgatgact tagcaggatc aactgaatat gtccaacagg
    13501 atcctaacat gcaaaaaatt gaaggggata tcaaaaataa ctttgagcag gcatttatga
    13561 tgtatcttcc ccgattatgt gagcactgtt tgaatgcgcc ttgtgtagcc tcttgtccat
    13621 caggtgcaat gtacaaacga gatgaagatg ggattgtttt agtagaccaa gaacgctgtc
    13681 gaggatggcg tttttgcatg actggatgtc catataagaa ggtctacttt aactggaaga
    13741 ctcataaggc tgaaaaatgt actttttgtt atccacgaat tgaagaaggt caaccaacag
    13801 tttgtgccga aacctgtgtc ggtcgaattc gatatattgg tgctattcta tacgatgctg
    13861 atcgagtaga agaggcagca tcaactcctg atgagagtaa gctgtatgaa gcacaacttg
    13921 gcttattcct cgatcccaac gatcctaaag ttgtcaagca agcactcaag gatggcattt
    13981 ctgaagagat gattgaagct gcacaaaagt caccgatcta taaaatggca gtaaaagaaa
    14041 aaattgcctt cccacttcac ccagaatacc ggacaatgcc aatggtttgg tacattccgc
    14101 cgctatcgcc agttatgagt tactttgaag gacgggactc aataaagaat cctgaaatga
    14161 tcttcccagg aattgatcaa atgcgggtgc ctgttcaata cttggcaagt ctattaactg
    14221 caggaaacgt tcctgtcatc aagaaagcct tatataaact tgcaatgatg cggctataca
    14281 tgcgtgctaa gactagtggt cgggattttg atagcagtaa actagaacga gttgatttaa
    14341 cagaagaacg ggcaacatca ctttatcgtt tactggcaat tgctaaatat gaagaccgct
    14401 ttgttattcc aagtagccaa aaggcagaaa tggaagatgc acaaaccgaa caaggtagtc
    14461 ttggctatga tgaatgtgaa ggctgtgcat tagctcccca acacaagagt atgtttaaga
    14521 aggcagaagc tggcaaatca actaatcaga tttatgctga tagtttctat ggagggattt
    14581 ggcgtgattg attttagacg attgacagat ttaaaggata cctttgccgt tctttctcgc
    14641 ttaattgatt atcctgatac agaaacgttt tcaccagaga ttcgtcaatt attacttaca
    14701 gataacgcat tatcaacagc aacgcgtgga gaattattaa gcctttttga tgaattagcc
    14761 gcactatctt caatcgaagt ccaagagatg tatgctcatc tttttgaaat gaaccgacgt
    14821 tatactcttt atatgtcata ctataagatg accgattccc gtgaacgagg gaccatttta
    14881 gcacggttga aaatgctata tgagatgttt ggtatatcag aagcgaccag tgaactttct
    14941 gattatttgc ctctattgtt agaatttcta gcatatggcg attatactaa tgatccgcgt
    15001 cgtcaggata tccaattagc attaagtgtg attgaagatg gaacttatac ccttttaaaa
    15061 aatgcagtga cagatagtga taatccctat attcagttaa tcaggcttac acgttcatta
    15121 attggttcgt gtattaaaat ggaggtgcga gaagatgcat aatggctggt caattttctt
    15181 atgggttatt tatccatata taatgttggc atcatttttc attggaacat ttgttagatt
    15241 taaatatttt catccctcaa ttactgccaa atcaagcgaa ctttttgaaa agaaatggct
    15301 aatgatcgga agcgttactt tccacattgg aattatttta gctttctttg gtcattgctt
    15361 aggaatgttt attccagcaa gttggacagc ttattttggg atcactgaac atatgtacca
    15421 catctttggg tcattgatga tgggaattcc agcagggatc cttgcgtttg tgggaattgc
    15481 aattctgact tatcgacgaa tgacttgttc tcgtgtttat aagacaagtg atatcaatga
    15541 tattattgtc gactgggctt tactgattac aattgcacta ggtctagcat gtactattac
    15601 gggtgcattt atcgattaca actatcgaac aacaattagt ccatgggcaa gaagcctatt
    15661 tgttcttaat cctcaatggc aattgatgcg ttcagtgcca ttaatttata aaattcacgt
    15721 tctctgtgga ttagcaattt ttggttactt cccatacacc cggttggttc atgctttaac
    15781 gctaccttgg caatatattt tccgtcgttt tattgtctat cggcgccgtg caagggttta
    15841 ttagtatata agaagatata ataaaagcat cagatttctt tacagggaaa ttctgggata
    15901 tctgtcaact ggtatggttg actaaaaata cttcctacga aaatgtaggg ggtatttttt
    15961 tacgcc
//
