LOCUS       c00022_gnlPro..        15385 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LPMNNKOO_22.
ACCESSION   c00022_gnlPro..
VERSION     c00022_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-05-01 00:19:18
            Original ID  :: gnl|Prokka|LPMNNKOO_22
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15385
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15385
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2268:5385]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2269..5385
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..15385
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15385
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             179..694
                     /locus_tag="ctg22_1"
                     /transl_table=11
                     /translation="MLAWLPFFLISLMFIVLLYACARSARTNIQRFKQLSLIAFLWALT
                     AFCYTPTSYNFGTQLVIQYIQWGPVKLNVIPFQQLDIEFWLNVLLTVPLGGLLAWNFPD
                     LPWRRFIWLGFLTGLTLELGQFILDWLVNLKRWVDIDDVITNWAGVIIGAAGYKIARHV
                     PGLRWLQK"
     CDS             complement(862..1851)
                     /locus_tag="ctg22_2"
                     /transl_table=11
                     /translation="MRMLEKIEQYIDSCIEAGDIYGASFSLITPKGINQYYHGKQGRDE
                     FAVGLDPAMIYDLASVTKVVGTTTRIFQLLSDHTIHLTDSVARFLPGFTHPEITIKNLL
                     LHNSGLPADIDNLDKMQREDLIKAVYDAPLVTAPGTTYVYSDLGFILLGWIIRAVDGSL
                     ARSIQDHVCYPLAMTNTGYNLNRPKIRFVPTEFDPRRGQIQGQVHDYKAFLLNGESGHA
                     GLFSTLTDLSVFIEMMLNFGEYQGKRVLDENVFDWLGEYDENGRTLGWERRAGRHQYFH
                     TGFTGPAVAFDLDRQIGLVVLTNRVYPTSDNQVWNQDRKRVFDLFFES"
     CDS             2269..4527
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_3"
                     /sec_met_domain="Gly_radical (E-value: 8.7e-39, bitscore:
                     126.9, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 1.4e-245, bitscore:
                     810.7, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MITSEKTTKPAAWKGFKGGHWQEEINIRDFIQNNFTQYNGDESFL
                     AGPTAATKTLNDKVLELKKQERAAGGVLDADTKVVATITSHGPGYIQKDLEKIVGLQTD
                     KPLKRAFMPFGGIRMADDALKSYGYTPDEENDKIFTEYRKTHNQGVFDVYTPDMRKARH
                     YKIITGLPDAYARGRLIPDLPRVAVYGIDRLMEDKANDFAHIGDGELTDDVIRLREEVQ
                     DQYRALADMKKMAASYGYDISKPATNAQEAIQWMYFAYLAAIKTQNGAAMSVGRIDTTM
                     DIFIQRDLDNGVLDESQAQELIDQFVMKLRMVRFIRTEEYNSLFSGDPIWATLSMCGLG
                     VDGQHHVTKTAFRILKTLDNMGAAPEPNITILWSDRLPEDFKRYATEVSIDSSTIQYEN
                     DDLMRVQWGTDYYGIACCVSAQPIADGIQYFGARANLAKAILYAINGGRDEIAGDQVGP
                     AYEPITSEYIDYDEFMKKLDKQMDWLADTYVNSLNAIHYMHDKYYYEAAQLALKNTDLD
                     RTFATGISGLSHAADSISAIKYGHVKVIRDERGIAVDFKADNDYPRYGNNDDRADDIAK
                     WLVKELYSKMNTHHLYRNAKLSTSVLTITSNVVYGKNTGTTPNGRQKGEPFSPGANPAY
                     GAEKSGALASLLSTAKLPYRYATDGISNTFGVTPNTLGHDLESRKDTLVNMLDGYMKND
                     GMHLNINVFNKDTLIDAQKHPEEYPTLTVRVSGYCVYFADLTKEQQDDVISRTFFESM"
     CDS             4564..5385
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 74; E-value:
                     4.8e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_4"
                     /sec_met_domain="Radical_SAM (E-value: 1.4e-26, bitscore:
                     88.4, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKQVSTTQAAAKEPLIGYVHSIETFGSVDGPGIRYVAFLQGCH
                     MRCQYCHNPDTWKLNVGDQMTADEILEDAAKYRAFWGKTGGITVSGGESLVQIDFILDL
                     FEKAKAMNISTCLDTSGQPFTREQPFFDKFERLMKVTDISLVDIKHIDSAKHKQLTQYG
                     NENILDMIQYMAQHHDDMWIRHVLVPQRTDYDEDLKKLGDYIAKIPNDVVQKVEVLPYH
                     TLGVKKYHEMKIKYRLEGIESPTQDRVANAEKLLHTADYNGYKTWMPLPKL"
     CDS             complement(5608..5919)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FeS_assembly_P"
                     /gene_functions="other (smcogs) SMCOG1048:Iron-sulfur
                     cluster assembly protein (Score: 67.1; E-value: 3.9e-21)"
                     /gene_kind="other"
                     /locus_tag="ctg22_5"
                     /sec_met_domain="FeS_assembly_P (E-value: 2.3e-20,
                     bitscore: 67.1, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTFKDRAFEALGHVIDPELGIDLVNLGLIYDAQLTAEGTAEIT
                     MTLTIAGCPLTEWLAKDIHDELIKLPEVNNIEIEIVWEPAWNESMMSREARMELGIHS"
     CDS             6979..7899
                     /locus_tag="ctg22_6"
                     /transl_table=11
                     /translation="LKTINLGHSNIQASSVALGIMRMDALDVAQATKVIDTAADLGINY
                     VDSADIYGGGQSSTIFGQALKQAHVSRDQLYIQSKGGIVPGKRYDFSKQHILAAVDGEL
                     QRLGVDYLDTFLLHRPDALMEPEEVAAAFDKLQTSGKVRHFGVSNFNPMQVDMLQAALN
                     QRLIINQLQFGIMHTGAIDFGLHTNMQDERSLNHDGEMIEYSRLHKMTIQAWSPYQYGN
                     FAGIFLDNPKFPELNNAMQALADEKQVTKSAIATAWILRHPAHFQVILGTMNPEHLAQN
                     AAGADVTLSRQEWYDIYFAAGNDLP"
     CDS             8069..8593
                     /locus_tag="ctg22_7"
                     /transl_table=11
                     /translation="MTSTCTICERIKLIQAHQNPYFVYELTTGYVVLADSQYFEGYTLF
                     LAKHHVTELHHLPAHEKLRYLEEMSIVQEACAQAFHADKMNIELLGNGDAHVHWHLFPR
                     HNGDTPNPGPVWWTPLETIYGDDVSLDIPRLSRLKRTLSVAIEATLNAREAELQALEAL
                     TRPASHRIDSN"
     CDS             complement(8688..8933)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GlcNAc_2-epim"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_8"
                     /sec_met_domain="GlcNAc_2-epim (E-value: 0.00088, bitscore:
                     13.1, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTAPLSSFEKNIPAVTELLAVDAELQTFFVALTPGYQREWARFI
                     FGTKAQATKERHIEVMKTVFRAGYKSKRVYDSRSDK"
     CDS             9106..9534
                     /locus_tag="ctg22_9"
                     /transl_table=11
                     /translation="MPKFDITLISPERAKAMLTEYKEQRKNSVPHLAHPGRYILPDYKL
                     TRRRAAFKIVKHTFLTPHYKSYVAMDSDNGHTLWFHNFGSLTEALFWLETGLKISDTDS
                     HSNYKEWMAKHTTEIETFKDLLREQKHKQGPKTKKKAK"
     CDS             complement(9637..10278)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lipase_GDSL_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_10"
                     /sec_met_domain="Lipase_GDSL_2 (E-value: 9.2e-19, bitscore:
                     63.0, seeds: 1564, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAISNGHVSFKRPAWLGDSITANNGLATVHYHDILAADWDVERSD
                     NLGISGSTIGSRYDAMAVRYQAIPEDADFIAVFGGVNDYGRDQPLGQYGDCDMTTFYGA
                     LMMLLTGLQTNWPTVPKLFISAIHIGSDFGGSFSAVTNGLGYRQSDYEAAIAQMTADYG
                     VPHLSLYRDAGMTFAIPAQAAIYSVDTLHPNNAGHRVIARKLQSFLDSHF"
     CDS             complement(11294..12961)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BCCT"
                     /gene_functions="transport (smcogs)
                     SMCOG1001:betaine/carnitine/choline family transporter
                     (Score: 411.1; E-value: 1.7e-125)"
                     /gene_kind="transport"
                     /locus_tag="ctg22_11"
                     /sec_met_domain="BCCT (E-value: 1e-124, bitscore: 411.1,
                     seeds: 90, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSSRFIILKSKNIDWWVYLPTIGLFAAASVVLLMGGHSLETSLS
                     GILNWLTNNMSWLYMSVYVITFIFFIYLGFSKLGKTKLGDPDDKPEFSTYHWGSMVYAT
                     GIDASILMLSMVDPLRYLQSPSFGVKPFSTSAYNYAHMLGQFNWGPMAWMMFAPATIAI
                     AYAMYVKHIKVQRLSAAISVLQGPGKGKQIARNTIDFLVIIGIMGGVGTSVGMEIPVIS
                     KVLSAVTGIADTMTLKLGLFALLFVIFAMAVFNGLKKGIGRLSAAHVWLAIGFLIVVLI
                     VGPTLYILNSETNSIGLFVNKFITLSTNTAPNGHATTMQRQTIFYWGWWLSFMPVMGLF
                     IARISRGRTIRQVLGGMLLWGSLGCVSFYAILGGYALYLQRMGIVNLVHILNTQGQAAV
                     IAAVLSTLPLKMIMLALYCLSCFIFLATTVSSFAFITSSFTSKKLAAGEQPSRFNRMSW
                     VVIFLVFSLGLVTVGGFESIQSICAMSGFPLTIVALVLLYSIHHDLTTDPVKEAAKANA
                     KAAELARRKRLARDVEITTKTDYARERRTARKRETEAD"
ORIGIN
        1 gttgtcaaca actaatttca ataattattt ggtggtgaga tgcatctgcc gtagcagcaa
       61 cgtttactaa tataccaatt gaagtaaaaa gtgtcaacac tttttctgaa tttcttttta
      121 ttaatagtca aaccagcttt ttttctctat actatttaat taaaggagcg actaaattat
      181 gctagcttgg ctaccattct ttttgatttc attaatgttt attgttctac tatacgcttg
      241 tgcgcgatca gcgcgcacaa atatccagcg ttttaagcaa ctcagtttaa ttgcctttct
      301 ctgggcctta actgcttttt gctacacacc taccagttac aattttggta cccaactcgt
      361 tattcaatat attcaatggg ggcccgttaa gctgaacgtg attcctttcc aacaacttga
      421 cattgaattt tggctcaacg ttctcctcac tgttccattg ggcggtttac tggcatggaa
      481 ttttcccgac ttgccttggc gtcgttttat ttggttggga tttcttacgg ggctaacact
      541 cgagctggga caattcattc ttgactggtt ggttaacctc aaacgttggg ttgatatcga
      601 tgatgtcatc acaaattggg ctggtgtcat tatcggtgcc gctggttata aaattgcacg
      661 tcatgttccc ggacttcgct ggttgcaaaa ataacgtata tatagaagca aaaagcaaaa
      721 tagcgtttgt ttagcaccca caagtgccaa acacttcagc ggtctagctg tcatgaaatc
      781 gtaattaaat aagcgtcgca gccttaagtg gctgcgacgc ttatttaatt taactactaa
      841 ctattaatga agctgccatc atcaggattc aaaaaacaga tcgaatactc gcttacgatc
      901 ttggttccag acctgattgt cactagttgg ataaactcga tttgttaaca caaccagccc
      961 aatttgacga tccaaatcaa aagcaactgc cgggccagta aaaccagtat ggaaatattg
     1021 atgtcgtccc gcacgtcgtt cccaacctaa cgtccggcca ttttcgtcat actcgcctaa
     1081 ccagtcaaag acattttcat ccagcacccg tttgccttga tattcaccaa agtttaacat
     1141 catttcaata aatacggata aatccgtcag cgttgagaac aagcctgcgt gaccactctc
     1201 accattcaac aaaaaggctt tataatcatg cacctgtcct tgaatctgac cccgccgcgg
     1261 atcaaactcc gtcggcacaa accgaatctt cggacgattt aagttataac ccgtattggt
     1321 catcgctagt ggatagcaaa cgtggtcttg aatactccga gccaatgagc cgtcaaccgc
     1381 acgaataatc catcccaata aaataaatcc caggtctgaa tagacatacg ttgtccctgg
     1441 cgccgtgacg agtggcgcat cataaaccgc tttgatcaga tcttcacgtt gcatcttatc
     1501 caggttatca atatctgccg gtagcccact attatgaagt aacaagtttt taatcgttat
     1561 ttcaggatga gtgaacccag gtaaaaaccg ggcaaccgag tccgttaaat gaatcgtgtg
     1621 gtccgataac aactgaaaaa tcctcgtcgt ggtccctaca accttagtta ccgatgctag
     1681 gtcataaatc atcgcaggat ctaagcccac ggcaaactca tcgcggccct gcttaccatg
     1741 atagtattga ttgatacctt taggggtgat caagctaaac gacgccccat aaatgtcgcc
     1801 agcttcaata caactgtcaa tatattgttc aattttttcg agcatccgca ttacgcccac
     1861 ctttcactac attcactagt ttctgcttat cttctttatg ataacgaact tcctcataaa
     1921 atcaacggca aacgctttta acaccctcca cacctcgttg cactttttat taattaacta
     1981 gttaaacact tgttacatta tggacaatat tccacttata tatcaaaaca agtcttgttt
     2041 ttagccgttt tctaaatata attaagtgaa ttaccaatgc ctatctagct atgtaagtac
     2101 tgttatatca acgttaatag tcaacttttc aataatagat tgcaaaaaaa taacccaaac
     2161 gtgaaataaa tcacctgaaa gcggttacaa atccagcaaa aaatgttatg attcaaatat
     2221 agaattttat caatcatttg attggattca aattatggag gcgagaaaat gattacatca
     2281 gaaaagacaa caaaaccagc agcttggaaa ggtttcaaag gcgggcactg gcaggaagaa
     2341 atcaacattc gtgattttat tcaaaataac ttcacacagt acaatggcga cgaaagcttc
     2401 ctggccggac caacagccgc tactaagacc ttgaatgaca aagtcttaga attaaagaaa
     2461 caagaacgtg ccgctggtgg tgtgttggat gctgatacta aagtcgttgc aacgattact
     2521 tcacacggcc ctggttatat tcaaaaagat ctcgaaaaga ttgttggtct ccagactgac
     2581 aagcctttga agcgggcctt catgccattt ggtggtattc gaatggctga tgacgctttg
     2641 aaatcatacg gttatacccc tgatgaagaa aacgacaaga ttttcactga atatcgcaag
     2701 actcataacc aaggcgtctt cgatgtttat actcctgaca tgcggaaagc acgtcactac
     2761 aagatcatca ccggactacc agatgcatac gcacgtggcc gtctcattcc tgatcttcca
     2821 cgggtcgctg tttatgggat cgatcgttta atggaagaca aagctaatga ctttgcccac
     2881 attggtgatg gtgaattgac tgatgatgtt attcgcctcc gtgaagaagt tcaagatcaa
     2941 taccgtgctt tagcagatat gaagaagatg gctgccagtt atggctacga tattagcaag
     3001 cctgcaacta atgctcaaga agctattcaa tggatgtact tcgcttactt agctgctatc
     3061 aagacccaaa acggcgctgc aatgtccgtt ggccggattg atacaacgat ggacatcttc
     3121 atccaacgtg acttggacaa tggtgttctg gacgaaagcc aagctcaaga attaattgat
     3181 caattcgtca tgaaactacg gatggttcgg ttcatccgta ctgaagaata caattctctc
     3241 ttctctggtg acccaatctg ggcaacctta tcaatgtgtg gtttaggcgt cgacggtcaa
     3301 caccatgtga ctaagaccgc tttccggatt ttaaagactt tggacaacat gggcgccgca
     3361 ccagaaccaa acatcacgat tttatggtca gaccgcttac cagaagactt caaacgttac
     3421 gcaactgaag tttcaatcga cagttcaacc attcagtatg aaaatgatga cttgatgcgg
     3481 gtacaatggg gtaccgatta ttatggcatt gcttgctgtg tttccgcaca accaattgct
     3541 gatggaatcc agtacttcgg tgcccgggca aacttagcca aagcgattct ttatgccatc
     3601 aatggtggcc gcgacgaaat tgctggagat caagttggcc ctgcttacga accaattact
     3661 tcagaataca tcgattacga cgaattcatg aagaaattag acaagcaaat ggattggtta
     3721 gctgacactt acgttaactc actgaatgca attcattata tgcatgataa gtactactat
     3781 gaagctgccc aattagcttt gaagaatact gatcttgatc ggacctttgc aactgggatt
     3841 tctggcttat cacatgccgc ggattcaatc tcagctatca agtatggtca cgttaaagta
     3901 attcgtgacg aacgtggtat cgccgttgac ttcaaagccg acaatgacta cccacgttat
     3961 gggaacaatg acgatcgcgc tgatgacatt gctaaatggt tagtcaaaga attatacagc
     4021 aagatgaaca cgcatcacct ctatcggaat gccaaacttt caacttctgt tttgacgatt
     4081 acctccaacg ttgtttatgg taagaacact ggtaccacgc caaatggccg tcaaaaaggc
     4141 gaaccattct caccaggtgc taaccctgca tacggtgctg aaaagagtgg tgcattagct
     4201 tcacttcttt caactgccaa attaccatac cgttacgcaa ctgacgggat ttccaacacg
     4261 ttcggcgtta cccctaacac gttaggccat gacctcgaat cacggaaaga cacgttagta
     4321 aacatgttag acggttacat gaagaacgat gggatgcact tgaacatcaa cgtcttcaat
     4381 aaagacactt tgattgatgc tcagaaacac cctgaagaat acccaacatt aacggttcgg
     4441 gtttctggct attgtgtcta cttcgcagat ttaaccaagg aacaacaaga tgacgttatt
     4501 tcacggacat tcttcgaatc aatgtaacat ttaatcttta atagttaaga aggcgaaagg
     4561 ctcatggaaa acaaacaagt ttcaacaacg caagcggcgg caaaggagcc tttgataggc
     4621 tacgttcact ccatcgaaac gtttggctcc gttgacggac caggtatccg ttacgtggca
     4681 ttccttcaag gatgccacat gcgttgccaa tactgtcaca accctgatac ttggaaactc
     4741 aacgttggcg atcaaatgac ggccgacgag attctcgaag acgcggctaa ataccgggct
     4801 ttctggggca agacgggtgg catcacagtc agtggtggtg aatcactggt acaaatcgac
     4861 ttcatcttag acttattcga aaaagccaag gcgatgaata tcagtacttg tctggatacc
     4921 tctggacagc cttttacccg agaacaacct ttctttgaca agttcgaacg tctaatgaag
     4981 gtcacggaca tttcgttggt cgacattaag cacatcgatt ctgccaaaca caagcagttg
     5041 acccagtatg ggaacgaaaa tatcttggat atgattcagt acatggccca acaccacgat
     5101 gatatgtgga ttcgtcacgt cctggttccc caacggactg attacgatga agacttgaag
     5161 aaactcggcg attacattgc taaaattcca aacgacgtcg ttcaaaaagt cgaagtattg
     5221 ccgtaccata ctttgggcgt taaaaaatat catgaaatga agatcaagta ccggcttgaa
     5281 ggaatcgagt ctccaaccca agatcgggtg gcaaatgccg aaaagctact gcacactgct
     5341 gattacaacg ggtacaagac atggatgcca ttgccaaaac tttaaatcgg catttctagc
     5401 atgactaaaa caccagcgat acaatcgtct acggatggtt gtgtcactgg tgtttttttg
     5461 ctggctcgac gcatgcacgt attgctggcc ggaattagta cagtggcacg caaaaaaggc
     5521 gccgcgagca aaccagcaac gtctttcctt aatcatgccc tatccaatga ccgtcagccc
     5581 ttggactggc tgcgaacagg ccggccacta actatgaatg cctagttcca ttcgagcttc
     5641 gcgggacatc atactttcgt tccaagcagg ttcccacaca atctcaatct cgatattgtt
     5701 aacttctggt aatttgatca gttcatcgtg aatgtcctta gccaaccatt cggtcaaagg
     5761 acagcccgca atggtcaacg tcatggtaat ttcagcggtt ccttccgccg tcaattgtgc
     5821 atcatagatc aaccctaagt taactagatc aattcctaat tcagggtcaa tgacatgtcc
     5881 tagcgcctcg aaggcccggt ctttaaacgt tgttgtcatc gtatctcgtc cttccatacc
     5941 agcttgaatt cactgattaa tcacgccaac gtttcgcggt ataagtgcca ccacacttga
     6001 tacacgtcat cgttatataa agcgctttct tgtctacttc tattgtaccg tatgtcagcc
     6061 catattcaat caattattag cgctaattag ccgacttttc aaacaatcgg tcaatcagca
     6121 aattatgcga ctatttctcg aaaaaattta ctataatccc cgatatagca gcgttttgag
     6181 tcactattga tttttattgc gaattcgcgg ttgtttttgt tgtaagcgtt tgcggtttat
     6241 gctattatac taagtgagga aaggaattaa tcctcgatta gcaaagcttc tcaaaagagt
     6301 ttggctgtcg ctgtaatgtt agacagctag tatcacagtt tgggtcgtta tcgaaaccgt
     6361 tttaagcgcc gtgaagcgtt atcggtctag cgagtgtcgt gagatttacg ttggatgact
     6421 gaacgttgac ccttagataa acgataaccg caaagaatta attggcatta gaatgacgaa
     6481 cagattttaa ctaagtttta gttggaaaca ggtgtctccg atgaccagtt gttagttcca
     6541 cattaccagt tccatttgta gactcaggta ttacaaagtt taaacggagg tgcatgtctg
     6601 ttacgaagac attcccaagt tttaaacgcg agtttaactt tcgttaaaac ccgtctaacg
     6661 agtcgcaatc aagtaacaac cttactttag atcgactata gcagatagtt acaataaata
     6721 cgggttagtc cgttagaagt tggacacgcg taaaattgaa tagcatgaag gtgtatcata
     6781 ttaacactga acaatttttc attgctaatc aggattattc ctcataagta gaactcaagc
     6841 agagaagcct tgggttctat ttttttgctc taaaatcaga tttaccaaca gtcggcacca
     6901 gacgtaaccg tttacatact cttacgaaaa ccgtatactg aatttaaatc aagttgcaca
     6961 ttgaggagga ctttagtttt gaaaacgatt aatttaggtc acagcaatat tcaagcttcc
     7021 agcgtggcac ttggcatcat gcgcatggac gctttggacg tcgcccaagc caccaaggtt
     7081 atcgataccg ctgctgattt aggcatcaat tacgttgatt cagctgatat ctacggtggt
     7141 ggtcaatcat cgaccatctt cggtcaagca ctcaagcagg ctcacgtatc gcgtgatcag
     7201 ctctatattc agtcaaaagg cggcattgtt cctggcaagc gttacgactt ttccaaacag
     7261 cacatactgg cagccgtgga tggcgagctt caacgcttag gtgttgatta tctcgacacc
     7321 ttcctcctcc atcgaccgga cgccctgatg gaacccgaag aagttgctgc cgcttttgac
     7381 aagttgcaaa ctagcggcaa ggtgcgccac tttggcgtct ctaacttcaa tcccatgcaa
     7441 gttgacatgc ttcaagcggc actaaaccaa cggctcatca tcaaccaact ccaatttggt
     7501 atcatgcata ccggtgcgat cgactttggc ttgcacacga acatgcagga cgaacgtagt
     7561 cttaaccacg acggcgagat gatcgaatac tcacggctcc ataagatgac gattcaagct
     7621 tggtcgcctt atcaatacgg taacttcgcg ggtatcttct tagacaatcc gaagtttcca
     7681 gaacttaata atgccatgca agcactcgcc gatgagaaac aggtcactaa atcagctatt
     7741 gcgaccgcat ggattctccg gcacccagcc cacttccaag tcatccttgg tacgatgaat
     7801 ccggaacatc tagctcaaaa tgctgctgga gcagacgtta cgctttctcg gcaagaatgg
     7861 tacgacattt actttgcagc tggcaacgat ttaccttaat cacgatcgac ctaacagaat
     7921 tgacgattag tttttacaat caaaacgacg accccaaatc aggattgatt ttcaggtcgt
     7981 cgttttttag acgtttcact aacatttttg atgtactcac cacatctacg cgtatactta
     8041 atcttatcaa gactcaggag gcgagcgaat gacatccact tgcacgatct gtgaacgaat
     8101 caaactaatt caggcacatc agaatcctta tttcgtttac gaactcacaa cgggctacgt
     8161 ggtccttgct gatagccagt actttgaagg ctacacgctc tttttagcca aacatcacgt
     8221 taccgaatta catcatttac cggcacacga gaagttacga taccttgagg agatgagtat
     8281 cgtccaggaa gcttgtgcgc aggcctttca tgcagacaaa atgaacattg aactactcgg
     8341 gaatggtgac gcgcatgttc attggcactt atttcctcgc cataacggtg atacgcccaa
     8401 ccccggtccc gtctggtgga caccgctgga aacaatttat ggtgatgatg tcagtctaga
     8461 cattccccgt ttaagccggt taaagcgcac gctcagcgta gcaattgagg ccacgcttaa
     8521 tgctcgggaa gcagaattgc aggctttaga ggcactcaca aggcctgcta gccacagaat
     8581 tgacagcaat tagaccaaat caggacccag acccgcttag atcttggtgg ctacacccca
     8641 attcttaatc gcaatccgtc accgtatttc aaattgccaa aatccaccta tttatccgac
     8701 cgactatcat acactcgctt agatttatag ccagctcgaa aaaccgtctt cataacttca
     8761 atgtgccgtt ccttagttgc ttgtgcctta gttccaaaaa taaagcgggc ccattcgcgc
     8821 tgataaccag gtgtcaaagc cacaaagaac gtttgcaatt cagcatcaac cgctaacaat
     8881 tcggttaccg ccggaatatt tttttcaaat gaactgaggg gtgctgtact cataatcaaa
     8941 cctccgatta gttttactta aatttactgt aagaaaggga aaatccctaa ttttcaggtt
     9001 tttatatttc gaattttcat aaaattgcgc tatcattata gtataagtat tattatttga
     9061 ctactataat taaccatact gctattcacc aaggggagcc ctgctatgcc aaaatttgat
     9121 atcaccctca tcagtcccga acgcgctaaa gcgatgttga ctgaatataa agaacaacgt
     9181 aagaactctg tcccacatct ggcccatcct ggccgctata tcttgccgga ttacaaatta
     9241 actcgtcgcc gggccgcatt caaaattgtt aaacatacct ttttaacgcc ccactacaag
     9301 tcttacgttg ccatggactc tgacaacggc cacacactct ggtttcataa tttcggttcc
     9361 ctaaccgaag ctttattctg gttagaaacc ggccttaaaa tcagcgatac cgactcccat
     9421 tctaactaca aggaatggat ggctaagcac actacggaaa tcgaaacctt caaagacttg
     9481 ctgcgcgagc agaagcataa acaagggccc aagactaaga aaaaagccaa gtagcccgtt
     9541 ttgacaccta gattcagata agcagcagta cgctcattag cgtgctgctg cttttattta
     9601 cgatcaactg tgccattcat tactgactag accaacctaa aagtggctat ccaaaaacga
     9661 ctgcagcttg cgtgcaatca cgcgatgacc ggcattgttc ggatgcaaag tatccaccga
     9721 ataaatggcc gcttgagcgg gaatcgcaaa cgtcattccc gcatcacggt acaagctcaa
     9781 atgtgggacg ccatagtctg cagtcatctg ggcaatcgct gcttcataat ctgactgacg
     9841 atacccgaga ccattagtca ccgcactaaa actgccccca aaatcagagc caatatgaat
     9901 tgctgaaata aataacttcg gcacggtcgg ccaattcgtc tgtaatcccg tcagtaacat
     9961 cattaacgcg ccataaaatg tcgtcatatc gcaatcaccg tattgcccta acggctgatc
    10021 ccgaccatag tcattgacgc ccccaaagac agcaataaaa tcagcatctt caggaatagc
    10081 ttgatagcgc accgccatcg catcgtagcg actcccaatc gttgaaccag agattcccaa
    10141 attatcgctc cgctcgacat cccaatcagc cgccaaaata tcatgataat gcaccgtcgc
    10201 caacccatta ttcgccgtaa tcgaatctcc caaccacgcc ggccgcttaa aactaacatg
    10261 cccattacta atcgccatag ccaatcctcc ctttactatc atcgctatca ttctaatcca
    10321 tcccacctga attatggtag aaagatgcct tttagggttg gttttctgtt cgtcagccgg
    10381 tgagcgtcct attccgacct ccggggctgg gtgacaattg ctggaacgca gccgacatcg
    10441 atttgagcta acgcataacc cgcgtcatct caaatacgag tcttattcta agccggaagg
    10501 aaatcacttc cgactaagaa taatttggct actgagcatt gtcacccagc ccctccagtc
    10561 tcaagccacg ggttgaagcc gagcattgtc tagccaacgg attaatgcgg tttgggcatt
    10621 tgtccgttgg catagcaagc acagacttta gtggcaccga acacgtttcg gtaagccgct
    10681 cgaatggctg atgaacggcc acttaacttg gtgcaattgg tcgttggcta ttttgatacc
    10741 ggaactttaa acgagacgtt agggttaccc taaccacttt gttgaggtgt tctattatta
    10801 ctatagtaat tccgaaatag cgagctatcc caatatcttt tcgacctaac agttgattaa
    10861 taaaattact gtttatggag aacaatgaca aattcatcaa aagttgggta tatcttcgtc
    10921 caccattcga atactgtccc gaatggaagg cgtttcggcc aatgctcagc ggtgaaattc
    10981 cacttagcaa gcgtccttgg cttggttagt agaagaccag tatttaagac gtggtcttcg
    11041 gcttaaatct gtgtccaccg cgttccagca attggcagaa atgcctggag agcggcgtag
    11101 gacgaacgaa ctaagcaggt ttacgctaac cggaactgtt tccagcgggc ctaagctggt
    11161 ggctgttgac tttaaataaa ggcatctttc taccattatt tcaaacaggt gggccaatct
    11221 taaaaggctc gtattatgga aatccataat acgagcctag tttaattgat atatttagtt
    11281 caactgagta gcgctaatcg gcttccgtct cacgtttccg tgcagtacgc cgttcgcgtg
    11341 cgtagtcagt tttagttgtg atttcaacgt cacgtgctag ccgtttccgg cgtgctaatt
    11401 cagctgcttt ggcattggct ttcgcagctt ccttgactgg atcagtcgtt aagtcgtgat
    11461 ggatcgagta cagtaagacg agcgcgacaa tcgttaatgg gaagccagac atcgcacaga
    11521 tggactgaat cgattcaaag ccaccgaccg tgacaagccc caatgagaag actaggaaga
    11581 taacgaccca gctcatccga ttgaaacgac ttggttgttc ccccgcggcc aactttttac
    11641 tagtaaatga cgaggtaatg aaggcaaatg aagataccgt cgttgctaag aaaataaagc
    11701 aagataggca gtacaaagcc agcataatca tcttcaatgg taaggtcgac aatactgctg
    11761 caatcacagc ggcttgtcct tgcgtattta agatatgaac taagttaacg atgcccatcc
    11821 gttgcaagta taaggcataa ccacccaaga tggcgtagaa actgacacaa cctaatgagc
    11881 cccatagcaa cataccaccg agtacctgac gaatcgtccg gccccgagaa atccgggcaa
    11941 tgaataagcc catgactggc ataaaggata accaccagcc ccagtagaag atcgtctgcc
    12001 gttgcatggt cgttgcgtga ccatttggtg cagtattcgt gctcaacgta ataaacttat
    12061 tgacaaacaa gccaatacta ttagtttctg agtttaaaat atacaaagtt gggccaacaa
    12121 ttaaaacaac gattaggaag ccaatcgcta accaaacatg ggcagcactt agccgaccga
    12181 ttcccttctt caagccatta aaaacagcca tggcgaaaat tacgaataat aaggcaaata
    12241 accctaactt taaagtcatc gtatcggcaa tcccggtaac ggcactcaaa acttttgaaa
    12301 tgacggggat ttccatcccg actgaagtac caacaccacc cataatccca ataataacga
    12361 gaaaatcaat cgtgttccgg gcaatttgct tacccttacc aggaccttgt agtactgaaa
    12421 ttgcggcact gagccgctga accttgatgt gtttaacata cattgcatag gcaattgcaa
    12481 tcgtggctgg cgcaaacatc atccacgcca ttggtcccca attaaattgt cccagcatgt
    12541 gcgcataatt atatgcagaa gttgaaaacg gcttgacgcc gaatgaaggg ctttggaggt
    12601 accgtaacgg gtcaaccatg ctcaacatta aaatgctggc atcgatcccg gtcgcgtaaa
    12661 ccatactgcc ccagtgatac gttgaaaatt ctggtttgtc atcaggatca ccaagtttgg
    12721 ttttccctaa cttactaaac cctaagtaaa tgaaaaagat aaaagtgatc acatataccg
    12781 acatataaag ccagctcatg ttatttgtga gccagttcaa gatgccactt aaactcgtct
    12841 ccagcgaatg gccccccatt aataaaacaa cggaagccgc cgcaaagagc ccaattgttg
    12901 gtaaatagac ccaccaatca atattcttac tttttaaaat aataaacctg ctactgagca
    12961 tatactctct atatttagat caaattcgtg gttcttccta ccagcaatgg tagtccccac
    13021 gcgtaaattt ccgactagca atcggtacac ccctccgagt taatcctcgg agcactcagc
    13081 accctgactg tatcaggttt gaccggcatt gtcatccgca ttctgtttgt gctaactcaa
    13141 aatcagtagc agaatttcct tctttccgtt ggttgaatcc ggacaacgcc atactgacaa
    13201 atgattttta attgcttaat cgacgttggt gttcatcttg tttagctagt gtttctatta
    13261 ccatcgtgcc tttagcacac gaccgtcgtc acaccacgta acgattaatg gttacactgc
    13321 tcttgctaat agataacccc cttgaatcac cagataagcc caccgcacaa ctgttagatt
    13381 aattgcttgg tgcaccaaaa aagcgcttag taccgggtaa caagttacca cctgcacagc
    13441 gcacgttggc ttatacaaat gctgatttca gtattttctg atatctgatg ttcgtttata
    13501 agtatactag tattaaatca gaagtaaaat caaccatttt gagccgtcga ggcctaaccc
    13561 gtcaaggatt agacgagttt tacacccata ttttttttga aactttttaa aagttttcgt
    13621 aataattagt ttttagttta gaatcattct tatctgtttc aattaaaccg atttcatgtt
    13681 attcttgtaa caagtaaaaa aacgttatca tctaaaagga ggggaactgc atgcggcact
    13741 actataaatt aattttaacg gtcagcgtcg gtatcattgc ggttatttta cagtttggtt
    13801 tgcactacca attggcagca caaatcatca ttacattaat ggggtcactt atggccttat
    13861 caatgttagt tgagatgatc aaaaccttac gttcaggtaa gtacggggtt gatttattag
    13921 caattacggc gattgtggca acactagctg tcggcgaata ttgggctagc cttgtcgttc
    13981 taattatgct cactgggggt gactcgttag aagattatgc ggccaaacga gcgaataccg
    14041 aattgaaagc cttgctcgat aattcaccac gtattgccca ccgctcagtc gccggccaat
    14101 taacagatat tgccgttgaa gatgtccaaa ttggtgatca gctagtcgtc aaacctggtg
    14161 agctagttcc agtagacggt caccttattc aaggaacggc actctttgat gaatcttcat
    14221 tgacgggtga atctaaacca gtcgacaagc acgttggcga tgacattatg tctggtgcgg
    14281 tcaacggcga tagtgccgtt acaatggttg ttgataaatt agccattgat agtcaatacc
    14341 aacagttagt caaattggtt aaagaatccg aatcacgacc agccaaattc gtacggctgg
    14401 ccgatcgcta tgcagtccca ttcaccttgg tagcatacgt cattgccgga gtagcttggg
    14461 cattcagcgg tgatccccac cgatttgcag aagtcctcgt agtggcttca ccttgcccgc
    14521 tgattctcgc cgcacccgtt gcactcgtct cagggatgag ccgaactagt cgaaacggaa
    14581 tcgtggtcaa gactggggac atgttggaga agttatctac ggctaagtcc gccgcgtttg
    14641 ataagacggg gaccattacc agtggtcaat taacagtcaa ccaaattgtt cctcagcctg
    14701 gttttactgc cgaacaaatc ttgcacctcg cagcgagcgc tgaccaaaac tcaagtcata
    14761 tcctggcccg ctcactcgtc aagtatgcga gtgccactag cctcagcccg gcaacacaat
    14821 tagcagaagt aacgggtaat ggggtcacgg caacgattga gcagcaacag gtcaaagtgg
    14881 gcaaacttaa attcgtcgca ccgactacaa ccgccaagcc acttgctacc actgctatct
    14941 acgtcggcat tgatgaccag tacgcgggtt acatcacgtt tatcgacaat gtccgccccg
    15001 aagcagccgc cacgcttcaa gcactccacg ctgagggcgt tcaaaacgtc atgatgctta
    15061 ctggtgacca acaggcaatt gctgatcata ttgccgccga tgtcggtatc gataccgttg
    15121 ctgccgacct cctacccgca gataagattg cccacttaaa ggctgtacca gcggccgaac
    15181 gccccgttat catggttggt gatggtgtta atgacgcgcc ttccttggct gttgctgacg
    15241 tcggcattgc catgggcgcc catggctcaa ctgctgctag tgaatcggcc gacgtcgtca
    15301 tcttaaaaga cgatctcagt cgcgtggtca cggcggtgcg cattgctaaa gataccatgc
    15361 aagtggctaa acaagccgtt tggat
//
