LOCUS       c00008_gnlPro..        12672 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HPCDGEOH_8.
ACCESSION   c00008_gnlPro..
VERSION     c00008_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-05-01 00:55:18
            Original ID  :: gnl|Prokka|HPCDGEOH_8
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12672
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12672
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[147:2672]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      148..2672
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..12672
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12672
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(148..909)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: 96.2; E-value: 3.7e-30)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_1"
                     /sec_met_domain="Fer2_3 (E-value: 7.5e-30, bitscore: 96.2,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 2.6e-11, bitscore: 36.9,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.0005, bitscore: 13.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEQKTIRFIITRQDTADSTPYDEEFEIPYRPNLNVISALMEIRR
                     NPVNVKGEKTTPVTWDMNCLEEVCGACSMVINGKPRQSCTALIDQLEQPIRLKPMKTFP
                     VVRDLQVDRSRMFDSLKKVKAWIPIDGTYDLGPGPRMPEKRRQWAYELSKCMTCGVCLE
                     ACPNVNSKSKFMGPAPMSQVRLFNAHPTGAMNKSERLEALMDEGGLADCGNSQNCVQSC
                     PKGIPLTTSIAALNRDTNLQAFRNFFGSDRV"
     CDS             complement(912..2672)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 296; E-value:
                     1.7e-90)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_2"
                     /sec_met_domain="FAD_binding_2 (E-value: 3.5e-90, bitscore:
                     296.0, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1e-42, bitscore:
                     138.2, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQSSIIVVGGGLAGLMATIKAAESGMAVKLFSIVPVKRSHSVCA
                     QGGINGAVNTKGEGDSPWEHFDDTVYGGDFLANQPPVKAMCEAAPSIIHLLDRMGVMFN
                     RTPEGLLDFRRFGGTQHHRTAYAGATTGQQLLYALDEQVRRYEVAGLVTKYEGWEFLGA
                     VLDDDRTCRGIVAQNLTNMQIESFRSDAVIMATGGPGIIFGKSTNSMINTGSAASIVYQ
                     QGAYYANGEFIQIHPTAIPGDDKLRLMSESARGEGGRVWTYKDGKPWYFLEEKYPAYGN
                     LVPRDIATREIFDVCVNQKLGINGENMVYLDLSHKDPKELDIKLGGIIEIYEKFMGDDP
                     RKLPMKIFPAVHYSMGGLWVDYDQMTNIPGLFAAGECDYSMHGGNRLGANSLLSAIYGG
                     MVAGPNAVKYVNGLESSAEDMSSSLFDAHVKKEEEKWADIMSMDGTENAYVLHKELGEW
                     MTANVTVVRHNDKLLKTDDKIQELMERFKKININDTTKWSNQGAMFTRQFSNMLQLARV
                     ITLGAYNRNESRGAHYKPDYPERNDDEWLKTTMAKHVSPYEAPEFEYQDVDVSLITPRK
                     RDYSKKKVAK"
     CDS             complement(2706..3314)
                     /locus_tag="ctg8_3"
                     /transl_table=11
                     /translation="MSGNREFYFRRLHSLLGVIPVGIFLIQHLVVNQFAARGAEAFNSA
                     AHFMDSLPFRYALEIFIIFLPLIYHAVYGVYIAFTAKNNAGQYSYMRNWLFVLQRVTGI
                     ITLIFVSWHVWETRIAAQMGAEVNFDMMANILSSPAMLGFYIVGVLSTIFHFSNGLWSF
                     AVTWGITVTPRSQRISTYVTLIIFVALSYVGLKAIFAFV"
     CDS             3607..4053
                     /locus_tag="ctg8_4"
                     /transl_table=11
                     /translation="MKSKFEESIDNLKEIEMNAYAYELIREIVLPDMLGQDYSSMMYWA
                     GKHLARKFPLESWEEFPAFFEEAGWGTLTNVSAKKQELEFELEGPIISNRLKHQKEPCF
                     QLEAGFIAEQIQLMNDQIAESYEQVKKRADKVVLTVKWDMKDPV"
     CDS             complement(4097..5323)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AA_kinase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_5"
                     /sec_met_domain="AA_kinase (E-value: 2.3e-55, bitscore:
                     180.8, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGLIVQKFGGTSVGSVEKIQNAANRAIAEKQKGHQVVVVVSAMGK
                     STDELVSLAKAISDQPSKREMDILLATGEQVTISLLSMALQEKGYDAVSYTGWQAGIRT
                     EAIHGNARITDIDTSVLADQLEKGKIVIVAGFQGMTEDCEITTLGRGGSDTTAVALAAA
                     LKADKCDIYTDVPGVFTTDPRYVKSARKLAGISYDEMLELANLGAGVLHPRAVEFAKNH
                     QVPLEVRSSTETEAGTLIEEESSMEQNLIVRGIAFEDQITRVTIYGLTSGLTTLSTIFT
                     TLAKRNINVDIIIQTQAEDKTGISFSVKTEDADQTVAVLEEYKDALEFEKIETESKLAK
                     VSIVGSGMVSNPGVAAEMFAVLAQKNILIKMVSTSEIKVSTVVSENDMVKAVESLHDAF
                     ELSKHPSAV"
     CDS             complement(5693..7465)
                     /locus_tag="ctg8_6"
                     /transl_table=11
                     /translation="MNKQLKEKLALLPDQPGCYLMKDRQQTVIYVGKAKVLKNRVRSYF
                     TGSHDAKTQRLVTEIEDFEYIVTSSNLEALILEMNLIKKHDPKYNVMLKDDKTYPFIKL
                     THERHPRLIVTRNVKKDKGRYFGPYPNVQAARETKKLLDRLYPLRKCSKLPDRVCLYYH
                     LGQCLAPCVKDISEETNRELVESITRFLRGGYNEVKKELEEKMHEAAENLEFERAKELR
                     DQIAHIESTMEKQKMTMNDLVDRDVFAYAYDKGWMCVQVFFIRQGKLIERDVSMFPLYQ
                     EADEEFLTFIGQFYSKNNHFLPKEILVPDSVDQSMIEQLLETNVHQPKKGPKKELLMLA
                     HKNAKIALKEKFSLIERDEERSIGAVQKLGEALNIYTPHRIEAFDNSNIQGTNPVSAMI
                     VFIDGKPYKKEYRKYKIKTVTGPDDYGSMREVVRRRYTRVLRENLPLPDLIIIDGGKGQ
                     INAARDVIENELGLDIPIAGLAKDEKHRTSNLLIGDPLEVVYLERNSQEFYLLQRIQDE
                     VHRFAISFHRQIRGKSAFQSVLDDIPGIGEKRKKMLLKHFGSVKKMKEASLEDIKKAGV
                     PAAAAQLLYDKLQK"
     CDS             complement(7601..7915)
                     /locus_tag="ctg8_7"
                     /transl_table=11
                     /translation="MAIVKATDQSFSAETSEGVVLADFWAPWCGPCKMIAPVLEELDQE
                     MGDKLKIVKIDVDENQETAGKYGVMSIPTLLVLKDGEVVETSVGFKPKEALQELVNKHL
                     "
     CDS             complement(8209..9717)
                     /locus_tag="ctg8_8"
                     /transl_table=11
                     /translation="MKGMIRGMSEHQAVIQTDIVKGTINKNIYGHFAEHLGRGIYEGIW
                     VGTDSDIPNINGIRKDVLEALKQLHIPVLRWPGGCFADEYHWANGVGDRKTMLNTHWGG
                     TIESNEFGTHEFMMLCELLECEPYICGNVGSGTVQEMAEWIEYMTFEEGTPMSDWRKQN
                     GREEPWKLKYFGVGNENWGCGGNMHPEYYADLYRRFQTYVRNYSGNEIYKIAGGANVDD
                     FNWTDVLMKKAAGLMDGLSLHYYTIPGDFWKGKGSATEFTEDEWFITMKKAKYIGELIQ
                     KHGTIMDRYDPEQRVGLIIDEWGTWFDPEPGTNPGFLYQQNTIRDALVAASHFHIFHQH
                     CRRVQMANIAQTVNVLQAMILTEGKRMLLTPTYHVFNMFKVHQDASLLATEIMSADYEW
                     KGETLPQISISASKQAEGDINITICNIDHQNKAEAEIELRGLHKAADHSGVILTAEKMN
                     AHNTFDDSHHVKPESFRQYTLSKNKLKVKLPPMSVVLLTLRADS"
     CDS             complement(9914..10891)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ETF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ETF_alpha"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 151.5;
                     E-value: 7.9e-47)"
                     /gene_kind="electron_transport"
                     /locus_tag="ctg8_9"
                     /sec_met_domain="ETF (E-value: 1.6e-46, bitscore: 151.5,
                     seeds: 129, tool: rule-based-clusters)"
                     /sec_met_domain="ETF_alpha (E-value: 2e-37, bitscore:
                     120.2, seeds: 511, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKKVIVLGEIRDGELRNVTFEAIAAGRTISGDGEVIGVLIGENV
                     QSIAQELIHYGADKVLTAEDPRLKTYTADGYSQVMRGVIEQENPDSVIFGHTAMGKDLS
                     PKLAARLQTGLISDAIDVSVTGGNVVFTRPIYSGKAFERIISTDPMIFATIRPNNIQAS
                     EKDTSRSGSIESMNVSLTDLRTVIQEVVKKTADGVDLSEAKIIVAGGRGVKSMEGFQPL
                     QELAEVLGAAVGASRGACDADYCDYALQIGQTGKVVTPDLYIACGISGAIQHLAGMSNS
                     KVIVAINKDPEADIFKIADYGIVGDLFEVVPLLTEEFKQLNIHS"
     CDS             complement(10927..11700)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ETF"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 159.7;
                     E-value: 2.4e-49)"
                     /gene_kind="electron_transport"
                     /locus_tag="ctg8_10"
                     /sec_met_domain="ETF (E-value: 4.9e-49, bitscore: 159.7,
                     seeds: 129, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLFVLMKRTFDTEEKIVIETGKIQDDGAEWIINPYDEYAIEEAI
                     QLKEKHGGTITAVTVGGEEAEKELRTALAMGCDQAVLINIEDDLEEPDQYSISQVLYHY
                     MKDQEFDLILGGNVAIDGGSGQVAPRLAELLDIPCITTITKLEINGTDAEAERDVEGDV
                     EKMKTTLPLLVTAQQGLNEPRYPSLPGIMKAKKKPLEELELDDLDLDEEDAEPKLKTIE
                     RFLPPKKEAGKLLQGEPDEQAKELVSLLRSEAKVI"
     CDS             complement(11715..12491)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ECH_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_11"
                     /sec_met_domain="ECH_1 (E-value: 4.8e-66, bitscore: 215.6,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNAISLAVDQFVAVLTIHNPPANALSSRILEELSSCLDQCETDAG
                     VRSIIIHGEGRFFSAGADIKEFTSLKGNEDSSLLAERGQQLMERIESFPKPIIAAIHGA
                     ALGGGLELAMACHIRIATEDAKLGLPELNLGIIPGFAGTQRLPRYVGTAKALELIGSGE
                     PISGKEALDLGLVSIGAKDEEEVLEKAKALAAKFAEKSPQTLASLLELLYSNKVYSYEG
                     SLKLEAKRFGEAFESEDAKEGIQAFLEKRKPQFKGE"
ORIGIN
        1 cttcaagcgg ataactcact cttgtcccca tagaaaaaac acctccaagt ctaatttcgg
       61 ataacaatca tccgtattca aacttgaagg tgtttttatt tgtctcatct tatggggtca
      121 gtcccatgcg gaagaggttt tttcttctta tactctgtcg cttccgaaga aattgcggaa
      181 cgcttgtaag tttgtatctc tattcaaggc tgcaatcgaa gtggtaagcg gaatcccctt
      241 cggacaggat tgaacacagt tttgcgagtt gccgcaatct gcaaggccac cttcatccat
      301 taatgcttct aatcgttcag atttattcat ggcgcctgtc ggatgcgcgt taaacaggcg
      361 gacttgcgac atcggtgcag gccccatgaa cttcgatttg ctgttcacat tcgggcaagc
      421 ttcgaggcag acgccgcatg tcatgcattt tgataattca tatgcccatt gacggcgttt
      481 ttccggcatt ctcggccccg gtcctaaatc gtacgtaccg tcaatcggta tccatgcttt
      541 aacttttttc aatgaatcaa acattctgct gcgatcaacc tgcaaatcac gaacgactgg
      601 gaatgttttc attggtttta aacggatcgg ctgttcaagc tggtcgataa gcgccgtaca
      661 agactggcgg ggttttccgt ttatgaccat tgaacatgcg ccgcatactt cctcaagaca
      721 gttcatatcc catgtgacag gggttgtctt ctcacctttg acattaaccg gattccggcg
      781 gatttccatc agagcggaaa tgacgttcag attcgggcgg tatggaatct caaattcttc
      841 atcgtaaggc gtgctgtcgg ctgtatcttg acgtgtgata ataaatcgta tggttttttg
      901 ttcactcatg attatttcgc caccttcttc ttcgagtaat cccgtttccg aggcgttatc
      961 agtgatacat cgacatcctg atactcaaat tccggcgctt catacgggct tacatgttta
     1021 gccattgttg ttttgagcca ttcatcatca ttacgttcag gataatccgg tttataatgg
     1081 gcgccccggc tttcattacg gttgtatgcg ccaagggtaa tcaccctagc aagctgaagc
     1141 atgtttgaga actggcgtgt gaacatcgct ccctggttgc tccattttgt cgtgtcattg
     1201 atgttgatct ttttgaagcg ctccattaac tcctgaattt tgtcatccgt tttcaaaagc
     1261 ttgtcattat ggcggacaac cgttacgttc gccgtcatcc actcaccgag ctctttgtga
     1321 agaacatagg cattttcggt tccgtccata ctcataatgt cagcccattt ttcttcttct
     1381 ttcttaacgt gagcgtcgaa taaagatgaa gacatgtctt ccgctgaaga ttctaagccg
     1441 tttacatatt tcaccgcatt cggaccggcc accatgcctc cgtaaatcgc agacagcaag
     1501 gagtttgctc ccaagcggtt gccgccgtgc atagaataat cacattcccc agccgcaaac
     1561 agtccaggga tgtttgtcat ttgatcgtaa tccacccata aaccgcccat agaataatgg
     1621 accgccggga agattttcat tggaagctta cgcgggtcgt ctcccatgaa tttctcataa
     1681 atctcaatga tgccgccaag cttaatatca agctctttcg gatctttatg agacagatcc
     1741 agatatacca tgttttcacc gttaatgccg agcttctggt tcacacacac atcaaatatt
     1801 tcgcgtgtcg caatatcacg cggcaccagg tttccgtatg ccggatattt ttcctccagg
     1861 aaataccatg gtttgccgtc tttatatgtc cacacgcgcc cgccttctcc acgcgctgat
     1921 tcactcatca gtcttagttt gtcatcgccc ggtatggctg tcgggtggat ttgaatgaat
     1981 tctccgtttg cataatacgc tccctgctga taaacgattg atgcagcaga tcctgtatta
     2041 atcatggagt tcgttgattt tccaaagatg attcccggtc cgcccgtcgc cataatgaca
     2101 gcgtctgaac ggaaggattc aatttgcatg tttgtcaggt tttgtgcaac aattccacgg
     2161 caggttctgt catcatctaa aacagcgcca aggaattccc agccttcgta ttttgtgacc
     2221 agacccgcaa cttcgtatct gcgcacttgc tcgtccagtg cgtaaagcag ctgctgtccc
     2281 gtcgtcgcac cagcataagc agttctgtgg tgctgtgtac ccccgaatcg gcggaaatca
     2341 agcaggcctt caggcgtccg gttaaacatg acgcccatcc ggtctaataa gtggatgata
     2401 gaaggcgccg cttcacacat cgccttgact ggcggctggt tggcaagaaa gtctcccccg
     2461 tataccgtgt catcaaaatg ttcccacgga gagtcacctt ccccttttgt attgaccgct
     2521 ccgtttatgc cgccttgcgc acaaactgaa tgagaacgtt tgacaggaac gatggaaaac
     2581 aatttaaccg ccattcctga ttccgctgct ttaattgtcg ccatgaggcc ggcaagaccc
     2641 ccgccgacta cgataatgct tgattgactc atgatagccc ctctccctct agtaatctag
     2701 tactcttaaa caaatgcaaa aatcgctttt aagcctacgt atgacagtgc aacaaaaata
     2761 atcagcgtaa cgtatgtcga aattctttga gaacgaggcg ttaccgtgat gccccatgta
     2821 acagcgaaag accataaacc gttcgagaag tggaaaattg ttgataaaac accgacaatg
     2881 taaaaaccaa gcatagccgg agagctcaaa atattcgcca tcatgtcgaa attgacctca
     2941 gcgcccattt gtgcagcaat gcgggtttcc cacacatgcc agctgacgaa aatgagggtg
     3001 atgataccgg ttacacgctg caggacgaat agccagtttc tcatgtagct gtattggccg
     3061 gcgttatttt tcgcagtaaa cgctatgtac acaccataaa ctgcatgata aattaatggt
     3121 aagaagataa taaaaatttc caaggcatac ctgaaaggca gactatccat aaaatgagca
     3181 gcgctattga atgcttcagc gccccttgcg gcaaactggt tgacgactaa atgctgaatg
     3241 agaaagatgc cgaccggtat gacgccaagc aaggaatgca atcttcgaaa ataaaactct
     3301 ctgttcccag acattacttt accccctgtt tgataagtgc gaaatgtgct aaatctcttc
     3361 ccccacttct ttcaattgta agcactttat taagatttat tgacaatttc attttactcc
     3421 tccctcaaaa gggcgtcaag aaaacgcgta cataaattat aattttccga attgattagt
     3481 tgattgaaaa attttatttt atcaatatat atttcttgct taatttttca taagaattac
     3541 aggatcattc tgtaatcctc ccccctgttt gagctataat atacgcagga gagaggggag
     3601 acagatatga agtctaaatt tgaagaatct attgacaacc taaaagaaat tgaaatgaac
     3661 gcctatgcct acgaactaat acgagagatc gttctcccag atatgcttgg ccaagattac
     3721 tcttccatga tgtattgggc aggaaaacat ctcgcccgta agtttcctct tgaatcatgg
     3781 gaggaatttc cggccttctt tgaagaagcg ggctggggaa ccctcaccaa cgtaagcgct
     3841 aaaaaacagg agcttgaatt tgaacttgaa gggccgatta tttccaaccg gcttaaacat
     3901 cagaaagaac cttgctttca gctggaggct ggttttatcg ctgaacaaat tcaattgatg
     3961 aatgatcaga ttgccgaatc atatgaacaa gtgaaaaaga gagccgataa agtggttctg
     4021 actgtgaaat gggatatgaa agacccagtg taatcaaaaa ggcggtgact gcatagtccc
     4081 gcctttttga ttgtcattac acagctgaag ggtgttttga aagctcaaat gcatcgtgaa
     4141 gcgactcgac tgctttcacc atgtcatttt cgcttacgac tgttgacact ttgatttcag
     4201 atgtgctgac cattttgatt aaaatgtttt tttgcgccag tacagcaaac atttcagccg
     4261 ctacaccggg atttgagacc atgccggatc caacaatgga tactttagcc aatttgcttt
     4321 ctgtctcgat tttctcaaat tccagcgcgt ctttatactc ttcaagcacc gcaacggttt
     4381 ggtctgcatc ttctgttttg acagagaagg aaattccagt cttgtcctcg gcctgcgttt
     4441 ggataatgat atccacgttt atgtttcttt tggcaagtgt cgtaaaaata gtagacaaag
     4501 ttgtcagacc gctagtcagc ccgtaaatgg ttactcttgt gatttgatct tcaaatgcaa
     4561 ttcctctgac aattaaattc tgttccatgg atgattcctc ctcaattaat gttcccgctt
     4621 cggtttctgt acttgaacgc acttctaacg gcacttggtg atttttcgcg aactcaactg
     4681 ctctcggatg aagaacgccg gcgcctaaat tggcaagctc aagcatttca tcgtatgaga
     4741 tgcccgcaag ttttctcgct gatttcacat agcgcggatc agttgtaaac acgcctggca
     4801 cgtctgtgta tatgtcacat ttatcagctt ttaaagcggc agccaaagca actgctgttg
     4861 tatctgaacc gccccggccc aatgtcgtaa tttcacaatc ctctgtcatg ccttggaatc
     4921 ctgcaacaat gacaattttt cctttttcaa gctggtctgc taaaaccgaa gtgtcgatat
     4981 ctgtaattct ggcgtttccg tgaatggcct ccgtacggat tcccgcctgc cagccagtat
     5041 aagacacagc atcatagcct ttttcctgca atgccattga aaggagtgaa atcgtgacct
     5101 gctcgcctgt cgccagcagt atatccattt cgcgtttgct cggctggtca gaaatagctt
     5161 ttgcaaggct gaccaattcg tcagtggatt ttcccattgc tgaaacgacg acaacgactt
     5221 gatggccttt ctgtttttct gcaattgcgc ggtttgccgc attttgaatt ttttcgactg
     5281 agccgacgga agtgcctccg aatttttgta caataagacc catgtattac caccctttac
     5341 attttggttc gtgcgggtga ggagaaagag cgctttgtcc acaataaaaa aagcaatgag
     5401 aggaatactc tcattgctta tcaattaatc atcataaatg attatgaaca acgagatagc
     5461 cctccaagaa aatgatttct tgacagcctt acatttattc aatgcacggc cagcaaataa
     5521 taccgatggg gttttacttg cttcggcgac gctccccttt cagccttttt cacagaatcc
     5581 atctttctcc aaaggcatac tcttgaagtt cgcacctcta tcttcaccat ataacacgat
     5641 ctaactatga aattagttca cattttatca gatcttattt aaaaggacaa cattattttt
     5701 gcaatttgtc gtaaaggagc tgagccgccg ctgcgggaac accggctttt ttgatgtcct
     5761 caaggcttgc ttccttcatt tttttaacgg aaccgaaatg ctttaacagc attttctttc
     5821 ttttctctcc gatacccggg atgtcgtcca aaacggattg aaacgcgctt tttccgcgga
     5881 tttgcctgtg aaaactgatt gcaaaacggt gcacctcgtc ctgaatgcgc tgcaggaggt
     5941 aaaattcctg gctgtttcgt tccagataca ccacctccag cggatcaccg atcagtaaat
     6001 ttgaggttct gtgtttttca tctttcgcta aaccggcgat cgggatatcc aagccgagtt
     6061 cattttcaat aacatccctt gctgcgttga tctgcccttt tcctccgtca atgataatca
     6121 gatcgggcag cggcagattc tcacgaagca ctctcgtata gcgtcttctg acaacctctc
     6181 tcatagaacc gtaatcatcc ggccctgtaa cggttttgat tttatatttg cggtattcct
     6241 ttttgtatgg tttgccatcg ataaacacaa tcatcgcaga aaccgggttt gtcccctgta
     6301 tgtttgagtt atcaaacgct tcaattctgt gcggcgtata aatatttaat gcctcaccta
     6361 gtttctgcac agccccgatt gaacgctcct cgtcgcgttc gattaaagag aatttttctt
     6421 tcaatgcgat tttcgcattt ttatgggcaa gcatgagcag ttcttttttc gggcctttct
     6481 tcggctggtg aacgtttgtt tccagcagct gctcgatcat ggattgatct acgctgtccg
     6541 gaactaaaat ctccttcgga aggaagtggt tgttttttga ataaaactgc ccgatgaacg
     6601 tgaggaactc ttcatctgct tcctgataaa gcgggaacat gctgacatcg cgttcaatga
     6661 gcttcccttg gcggatgaaa aagacctgca cgcacatcca gcccttatcg tacgcgtacg
     6721 cgaatacatc acggtcgact agatcgttca tcgtcatttt ttgtttttcc atcgttgatt
     6781 caatatgggc aatttggtca cgaagctctt ttgctcgttc aaactcaaga ttctcagcag
     6841 cttcatgcat tttctcttca agctcttttt tgacctcatt atagccgccc cttaagaaac
     6901 gtgtaatgct ttcaaccagc tctctgttcg tctcttcgga aatatccttt acgcacggag
     6961 cgaggcattg gcccagatga tagtaaaggc acactctgtc cgggagcttg gagcattttc
     7021 tgagaggata cagacggtcg agcagttttt ttgtttccct tgctgcctgt acattcggat
     7081 acggcccgaa atagcgccct ttgtcttttt tgacattgcg ggtgacaatc agccttgggt
     7141 ggcgttcatg ggtgagtttt atgaaaggat aggttttgtc gtctttgagc atgacgttgt
     7201 atttcggatc atgctttttg atcagattca tttctaaaat aagcgcttca agattggagg
     7261 acgtcacgat atattcaaaa tcctcgattt ccgtcacaag cctttgggtt ttcgcgtcgt
     7321 gagaaccggt gaagtaggag cgcactctgt ttttcagcac ttttgctttt cctacgtaga
     7381 tcacagtctg ctgccggtcc ttcatgagat aacaacccgg ttgatcggga aggagggcga
     7441 gtttttcttt cagttgtttg ttcatatgtt acccttcctt atgtttaatc ctttatatcc
     7501 agtttaacac gaacgtttgt ttttctctat ggttcacaat tggcgaataa aaaaagcgat
     7561 ccctcaatcg gaatcgctct ggcatgtaag cagcggaaaa ttaaagatgt ttgtttacaa
     7621 gctcttgaag cgcttctttt ggtttgaagc cgactgaagt ttcaactact tcgccgtctt
     7681 ttaacacaag aagagtcggg atgctcataa cgccgtattt tccggcagtt tcttggtttt
     7741 cgtctacatc gatttttacg attttcagtt tgtctcccat ttcttgatcc aattcttcaa
     7801 gaacaggtgc aatcatttta caaggtccgc accaaggagc ccagaagtct gccagtacga
     7861 cgccttcgct tgtttcagct gagaaagatt gatcagttgc ttttacgata gccattattg
     7921 aattcctcca atgtgaaatg atgattttta gtatagcatc tcccattcgt tcacgctatt
     7981 ttaatgctta caaattattt tttcctgatc acagccggtt tactcatttt tatatggttg
     8041 aatgggatat gctctttttt taaaacacaa atctgataat ggccccaatc actacaattg
     8101 ccccaataat cattaaaatg gtacgaagca taagatcaca tctcctcttc actgtcattt
     8161 aaaacctgaa aaagagcgcc ggcatgaagc tccggcgctc ttgcgcgatt aagaatcagc
     8221 acgcagcgta agcaagacga ctgacattgg cgggagtttt actttcagtt tgtttttgct
     8281 gagcgtgtat tgcctgaagg attccggttt gacatgatga gaatcgtcaa acgtgttatg
     8341 cgcattcatt ttttctgccg taagaatgac tccggaatgg tccgctgcct tgtgtaggcc
     8401 cctcagctcg atttccgcct ccgctttgtt ttggtgatcg atgttgcaaa tagtgatatt
     8461 gatatcacct tcagcttgtt tcgacgctga aatgctgatt tgcggaagcg tttcaccctt
     8521 ccattcatag tcggcagaca ttatctctgt tgctaaaaga gaagcgtcct ggtgcacctt
     8581 aaacatattg aatacatggt acgtcggtgt caaaagcatc cgcttgccct cagtcaaaat
     8641 catcgcttgt agaacgttta ctgtttgggc gatgttggcc atttgcaccc ggcggcaatg
     8701 ctgatggaaa atgtggaaat gagaagccgc caccagtgca tcacgaatgg tgttttgctg
     8761 atataagaaa ccgggattcg tgcctggctc gggatcaaac cacgtgcccc attcatcaat
     8821 aatcagcccg acccgctgct ccggatcgta ccggtccata atcgtgccgt gtttttgaat
     8881 caattcaccg atgtatttgg cttttttcat cgtaataaac cattcatctt ccgtgaattc
     8941 tgtggctgat cctttgcctt tccagaaatc ccccggaatc gtgtaataat gaagactcaa
     9001 cccgtccatc aggccagcgg cttttttcat aagcacgtcc gtccaattaa aatcatccac
     9061 atttgcgccg cctgcaattt tataaatttc attcccgctg taattgcgga cataagtctg
     9121 aaaacgccgg tacagatctg cgtagtattc gggatgcatg ttgccgccac agccccagtt
     9181 ttcattaccc acgccgaaat atttcagctt ccaaggctct tctcttccat tttgttttct
     9241 ccagtctgac atcggcgtgc cttcttcaaa tgtcatatac tcaatccact ccgccatttc
     9301 ctgaacggtt ccgcttccga cattgccgca aatatatggc tcgcattcaa gcagctcgca
     9361 aagcatcata aattcatgcg ttccgaattc atttgattca attgtaccgc cccagtgagt
     9421 gttcagcatt gtcttacggt caccgacacc gtttgcccaa tggtattcgt ccgcaaaaca
     9481 cccgcctggc cacctgagga cagggatgtg cagctgtttg agcgcctcca gcacgtcctt
     9541 tcgtatcccg ttgatattgg ggatgtctga gtccgttccg acccagatcc cctcataaat
     9601 ccctcttcct aaatgctcag caaaatgacc gtatatattt ttgttaatgg ttccttttac
     9661 gatatctgtt tgaatcactg cttgatgttc agacatgcct ctgatcattc ctttcatacg
     9721 gatatgaaaa gcaccacagt caaatatgtg atctgtcttt tgcctgagga gtcagcatga
     9781 atataagcgc ttttaaagta accatattat atatgttcgt acatgtcaac gtcattttct
     9841 atcgttttta tatttgtacg tatgtattta taaatatgga aaaatcccga acttttaaag
     9901 tccgggattt cctttatgag tgtatattca attgtttgaa ttcctcagtt aataacggga
     9961 caacttcaaa taaatcaccg acgatgccgt aatccgctat tttaaagata tcggcttcgg
    10021 ggtctttatt gatggcgacg atcaccttgc tgtttgacat gccggccaaa tgctggatgg
    10081 cgccggaaat gccgcatgca atgtacaaat ccggagtgac gactttcccg gtctgcccga
    10141 tttggagcgc gtaatcgcaa taatcagcgt cacatgcccc gcgagaagcc ccgactgcgg
    10201 cccctagcac ctctgcaagc tcctgcagcg gctgaaatcc ttccatgctt ttgactcctc
    10261 ggccgcccgc aacgataatt ttcgcttcgg agagatcaac accgtccgcc gtttttttca
    10321 cgacctcttg aatcacagtg cggaggtcag taagagagac attcatgctt tcgatgcttc
    10381 ccgacctgct ggtgtctttt tctgaagctt gaatgttatt ggggcgaatt gttgcaaaga
    10441 tcatcggatc ggttgaaatg atgcgttcaa aagctttccc cgagtaaatc ggccgtgtga
    10501 acacaacatt ccctccggta acgcttacat ctatagcatc agaaattaag cctgtttgca
    10561 gacgggcagc aagcttcggt gaaagatcct tgcccattgc cgtatgcccg aagatgactg
    10621 aatcaggatt ttcttgctcg ataacacctc tcatgacctg gctgtacccg tctgccgtgt
    10681 atgttttcag cctcgggtcc tcagcggtaa gaactttatc tgctccgtaa tgaataagct
    10741 cttgtgcaat gctttgtaca ttttcaccga tgagaacacc gatgacttct ccatctcctg
    10801 aaatggttct tcctgcagct attgcttcaa aggtgacatt ccgcaattcc ccatcgcgta
    10861 tttctccaag cacgatcact ttttttccca ttctaacatc cccctgtttc tttgaatgtc
    10921 caagctttaa atgactttag cttcgctgcg gagcaatgag acaagctctt ttgcctgttc
    10981 gtcaggctca ccttggagaa gcttcccggc ttcttttttc ggcggcagaa aacgctcaat
    11041 ggttttcagc tttggttcag catcctcttc gtccaggtca agatcatcaa gttcaagctc
    11101 ttcaagcggc tttttcttag ccttcataat tcccggaagc gatggatagc gcggctcgtt
    11161 taagccctgc tgagctgtga caagcaatgg gagcgtcgtt ttcatttttt caacatcccc
    11221 ttcgacgtcc ctttctgctt ctgcatcagt gccgttgatt tcgagtttgg tgatcgtagt
    11281 gatacatgga atgtccagta gctcggcaag ccgaggcgcc acttgtcctg atcctccgtc
    11341 aatggcaaca tttccgccga gaatcaaatc aaactcctga tccttcatat agtggtataa
    11401 aacttgagaa atggaatatt ggtcgggttc ttcgagatca tcttctatgt tgattaaaac
    11461 agcttggtca caacccatgg caagcgccgt acgcaattct ttctccgctt cttcaccgcc
    11521 gaccgtgacg gcggtgatcg tgccgccatg cttttccttc agctggatag cttcttctat
    11581 cgcgtactca tcatatggat taatgatcca ttccgctccg tcatcctgaa tctttcctgt
    11641 ttcaatgacg attttttctt ctgtgtcaaa cgtccgtttc atcagtacaa atagattcat
    11701 gatcatatcc ccttttattc gcctttgaac tgaggctttc ttttttcgag aaatgcctgg
    11761 atgccttcct tggcgtcctc tgactcaaat gcttccccaa atcgctttgc ttcaagcttt
    11821 aagctgcctt cataggaata caccttgttg gaataaagaa gttcaagcaa agatgccagc
    11881 gtttgcgggc tcttctctgc aaacttagcg gcaagtgctt ttgctttttc aagcacttct
    11941 tcctcatctt ttgctccaat tgagacaagt ccgagatcaa gcgcttcttt tccggatatt
    12001 ggttctcctg atccgatgag ctctaatgct ttggctgtgc cgacatatct cggaaggcgc
    12061 tgtgtccccg caaaacccgg aatgataccg agattaagct ccgggagccc cagcttagca
    12121 tcttctgttg cgattctgat atgacaggcc atcgcaagct ccagcccgcc tccgagagca
    12181 gcgccgtgaa tcgctgcgat aatcggtttt ggaaaacttt cgattctctc cattaactgc
    12241 tggccgcgct cagcgagcaa tgaggaatcc tcattgcctt taagcgatgt aaattcttta
    12301 atatcagcgc cggctgagaa aaatcttccc tcgccgtgaa tgataatgct tcgtacgcct
    12361 gcatctgtct cacattgatc aagacaggaa gacagctctt ctaatatccg gcttgaaagc
    12421 gcgtttgccg gcggattgtg aatcgtcaag actgccacaa attgatcaac cgcaagtgaa
    12481 attgcattca taggacagaa ctcctttact tattgtgaat tccggatacc aataattcta
    12541 aaacgctgtt tgaaagcgca acgagatcgt acttttggtc attcatcacc caagttgtca
    12601 cagtttcgtc aatcgttcca aaaatcatct gccgggcgag gcggacgtcg aggccttctt
    12661 ttaattcgcc tg
//
