## Fri May 2 06:57:24 2025 ## emapper-2.1.12 ## /home/m128030022/anaconda3/envs/eggnog/bin/emapper.py -i /home/m128030022/prbbiotics_cp/prokka_results/GCA_047462775.1/GCA_047462775.1.faa --temp_dir /home/m128030022/prbbiotics_cp/probiotics_new/databases/probiotics_DB/probiotics_db/GCA_047462775.1/2.eggNOGmapper --output_dir /home/m128030022/prbbiotics_cp/probiotics_new/databases/probiotics_DB/probiotics_db/GCA_047462775.1/2.eggNOGmapper --output eggNOG_out --override --cpu 14 -m diamond --sensmode fast ## #query seed_ortholog evalue score eggNOG_OGs max_annot_lvl COG_category Description Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction PFAMs BJHFPPGC_00001 1046629.Ssal_01652 4.13e-178 496.0 COG0652@1|root,COG0652@2|Bacteria 2|Bacteria O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ppiA - 5.2.1.8 ko:K01802,ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 - - - ko00000,ko00001,ko01000,ko03110,ko04147 - - - Pro_isomerase BJHFPPGC_00004 1302863.I872_07720 3.98e-09 56.6 COG5444@1|root,32YNG@2|Bacteria,1VJMI@1239|Firmicutes,4HPD8@91061|Bacilli 91061|Bacilli S Protein of unknown function, DUF600 - - - - - - - - - - - - DUF600 BJHFPPGC_00005 1046629.Ssal_00998 8.28e-196 545.0 COG1131@1|root,COG1131@2|Bacteria,1V5JQ@1239|Firmicutes,4HM69@91061|Bacilli 91061|Bacilli V AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran BJHFPPGC_00006 1121864.OMO_01583 4.36e-71 224.0 2DX6G@1|root,343KN@2|Bacteria,1UKKF@1239|Firmicutes,4HVY2@91061|Bacilli 91061|Bacilli S ABC-2 type transporter - - - - - - - - - - - - ABC2_membrane BJHFPPGC_00007 1046629.Ssal_01001 3.09e-125 358.0 2FFHU@1|root,347FA@2|Bacteria,1W0N0@1239|Firmicutes,4HZDI@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_00009 1046629.Ssal_01647 2.35e-213 589.0 COG0583@1|root,COG0583@2|Bacteria,1V53I@1239|Firmicutes,4HIEU@91061|Bacilli 91061|Bacilli K transcriptional regulator (lysR family) lysR - - - - - - - - - - - HTH_1,LysR_substrate BJHFPPGC_00010 435842.HMPREF0848_00152 3.78e-99 288.0 COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,4HIR4@91061|Bacilli 91061|Bacilli MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins lspA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.4.23.36 ko:K03101 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_A8 BJHFPPGC_00011 435842.HMPREF0848_00153 2.52e-208 576.0 COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,4HBG2@91061|Bacilli 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil rluD GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 BJHFPPGC_00012 1046629.Ssal_01644 5.91e-114 327.0 COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,4HGYE@91061|Bacilli 91061|Bacilli F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant pyrR GO:0003674,GO:0003700,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000,ko03000 - - - Pribosyltran BJHFPPGC_00013 1046629.Ssal_01642 1.16e-280 769.0 COG2233@1|root,COG2233@2|Bacteria,1TQKX@1239|Firmicutes,4HAEU@91061|Bacilli 91061|Bacilli F uracil Permease pyrP - - ko:K02824 - - - - ko00000,ko02000 2.A.40.1.1,2.A.40.1.2 - - Xan_ur_permease BJHFPPGC_00014 1046629.Ssal_01641 5.83e-222 612.0 COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,4H9M6@91061|Bacilli 91061|Bacilli F Belongs to the ATCase OTCase family pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15490 OTCace,OTCace_N BJHFPPGC_00015 1046629.Ssal_01640 7.9e-270 737.0 COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,4H9Z0@91061|Bacilli 91061|Bacilli F carbamoyl-phosphate synthetase glutamine chain carA GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_sm_chain,GATase BJHFPPGC_00016 904306.HMPREF9192_0437 0.0 2042.0 COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,4HAEY@91061|Bacilli 91061|Bacilli F carbamoyl-phosphate synthetase ammonia chain carB GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS BJHFPPGC_00017 435842.HMPREF0848_00160 6.38e-159 447.0 COG2265@1|root,COG2265@2|Bacteria,1V4AQ@1239|Firmicutes,4HHBA@91061|Bacilli 91061|Bacilli J Putative SAM-dependent methyltransferase - - - - - - - - - - - - SAM_MT BJHFPPGC_00018 435842.HMPREF0848_00161 8.9e-249 689.0 COG0845@1|root,COG0845@2|Bacteria,1VBR9@1239|Firmicutes,4HG5X@91061|Bacilli 91061|Bacilli M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K02005 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_D23 BJHFPPGC_00019 904306.HMPREF9192_0440 1.32e-156 440.0 COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,4HBMF@91061|Bacilli 91061|Bacilli V ABC transporter, ATP-binding protein salX - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran BJHFPPGC_00020 435842.HMPREF0848_00163 5.59e-272 746.0 COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,4HF9U@91061|Bacilli 91061|Bacilli V permease protein - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD BJHFPPGC_00021 435842.HMPREF0848_00164 1.7e-101 295.0 COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,4HH0N@91061|Bacilli 91061|Bacilli J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02864 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L10 BJHFPPGC_00022 264199.stu0537 6.49e-65 199.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,4HIGQ@91061|Bacilli 91061|Bacilli J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation rplL - - ko:K02935 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L12,Ribosomal_L12_N BJHFPPGC_00024 1123315.AUIP01000021_gene2248 3.14e-123 382.0 COG3942@1|root,COG3942@2|Bacteria,1VPFZ@1239|Firmicutes,4HFGV@91061|Bacilli 91061|Bacilli M CHAP domain protein XK27_00530 - - - - - - - - - - - CHAP,Peptidase_M23 BJHFPPGC_00025 435842.HMPREF0848_00171 1.4e-134 381.0 COG5340@1|root,COG5340@2|Bacteria,1V3JU@1239|Firmicutes,4HMVW@91061|Bacilli 91061|Bacilli K Transcriptional regulator, AbiEi antitoxin - - - - - - - - - - - - AbiEi_4 BJHFPPGC_00026 1046629.Ssal_01630 0.0 969.0 COG1292@1|root,COG1292@2|Bacteria,1TRS6@1239|Firmicutes,4HA7U@91061|Bacilli 91061|Bacilli M Belongs to the BCCT transporter (TC 2.A.15) family opuD GO:0003674,GO:0005215,GO:0006810,GO:0006811,GO:0006812,GO:0006950,GO:0006970,GO:0008150,GO:0008324,GO:0008519,GO:0009266,GO:0009409,GO:0009628,GO:0015075,GO:0015101,GO:0015199,GO:0015651,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0022857,GO:0031460,GO:0034220,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0072337,GO:0072349,GO:0072488,GO:0098655 - ko:K05020 - - - - ko00000,ko02000 2.A.15.1.1,2.A.15.1.11 - - BCCT BJHFPPGC_00027 1046629.Ssal_01629 2.89e-36 123.0 COG0583@1|root,COG0583@2|Bacteria 2|Bacteria K DNA-binding transcription factor activity - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - HTH_1,LysR_substrate,NMT1_2 BJHFPPGC_00028 435842.HMPREF0848_00173 0.0 1093.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H9SC@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein msbA_1 - - ko:K18887 ko02010,map02010 M00706 - - ko00000,ko00001,ko00002,ko02000 3.A.1 - - ABC_membrane,ABC_tran BJHFPPGC_00029 1046629.Ssal_01626 0.0 1122.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein lmrA - - ko:K06147,ko:K18888 ko02010,map02010 M00706 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran BJHFPPGC_00030 1046629.Ssal_01625 3.53e-254 696.0 COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,4H9PT@91061|Bacilli 91061|Bacilli J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) queA GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 ko:K07568 - - - - ko00000,ko01000,ko03016 - - - Queuosine_synth BJHFPPGC_00031 1046629.Ssal_01624 2.68e-160 449.0 COG0363@1|root,COG0363@2|Bacteria,1TP10@1239|Firmicutes,4HAG4@91061|Bacilli 91061|Bacilli G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion nagB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006040,GO:0008150,GO:0008152,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135 3.5.99.6 ko:K02564 ko00520,ko01100,map00520,map01100 - R00765 RC00163 ko00000,ko00001,ko01000 - - - Glucosamine_iso BJHFPPGC_00032 1046629.Ssal_01622 2.27e-249 682.0 COG1054@1|root,COG1054@2|Bacteria,1TRG7@1239|Firmicutes,4HA0J@91061|Bacilli 91061|Bacilli S Belongs to the UPF0176 family ybfQ - - ko:K07146 - - - - ko00000 - - - Rhodanese,Rhodanese_C BJHFPPGC_00033 1046629.Ssal_01621 5.4e-39 129.0 COG1476@1|root,COG1476@2|Bacteria,1VERT@1239|Firmicutes,4HNID@91061|Bacilli 91061|Bacilli K Transcriptional XK27_00085 - - ko:K07729 - - - - ko00000,ko03000 - - - HTH_3 BJHFPPGC_00035 264199.stu0551 5.18e-174 486.0 COG2820@1|root,COG2820@2|Bacteria,1V6T2@1239|Firmicutes,4HCSE@91061|Bacilli 91061|Bacilli F Phosphorylase superfamily - - - - - - - - - - - - PNP_UDP_1 BJHFPPGC_00036 1046629.Ssal_01618 2.65e-148 419.0 COG1814@1|root,COG1814@2|Bacteria,1V6KW@1239|Firmicutes,4IPIC@91061|Bacilli 91061|Bacilli S VIT family - - - - - - - - - - - - VIT1 BJHFPPGC_00037 264199.stu0553 6.29e-162 454.0 COG1187@1|root,COG1187@2|Bacteria,1TQZ2@1239|Firmicutes,4H9VU@91061|Bacilli 91061|Bacilli J Belongs to the pseudouridine synthase RsuA family rsuA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19 ko:K06183 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 BJHFPPGC_00038 1046629.Ssal_01616 1.27e-271 743.0 COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,4H9WQ@91061|Bacilli 91061|Bacilli E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase hipO2 - - ko:K01436,ko:K21613 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 BJHFPPGC_00039 1046629.Ssal_01614 3.36e-250 688.0 COG0686@1|root,COG0686@2|Bacteria,1TNZ5@1239|Firmicutes,4HABX@91061|Bacilli 91061|Bacilli C Belongs to the AlaDH PNT family ald - 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 - R00396 RC00008 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N BJHFPPGC_00041 1046629.Ssal_01611 3.34e-159 449.0 COG2021@1|root,COG2021@2|Bacteria,1UUC7@1239|Firmicutes 1239|Firmicutes E Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1 BJHFPPGC_00042 435842.HMPREF0848_00188 6.89e-314 855.0 COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4HBZF@91061|Bacilli 91061|Bacilli C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family merA - - - - - - - - - - - Pyr_redox_2,Pyr_redox_dim BJHFPPGC_00043 904306.HMPREF9192_1285 6.02e-191 532.0 COG1577@1|root,COG1577@2|Bacteria,1TPVW@1239|Firmicutes,4IRCB@91061|Bacilli 91061|Bacilli I mevalonate kinase mvk - 2.7.1.36 ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 M00095 R02245 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N BJHFPPGC_00044 1046629.Ssal_01607 5.15e-219 605.0 COG3407@1|root,COG3407@2|Bacteria,1TQXR@1239|Firmicutes,4HAM6@91061|Bacilli 91061|Bacilli I diphosphomevalonate decarboxylase mvaD - 4.1.1.33 ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095 R01121 RC00453 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N BJHFPPGC_00045 1046629.Ssal_01606 3.96e-211 586.0 COG1577@1|root,COG1577@2|Bacteria,1TPKP@1239|Firmicutes,4HWXG@91061|Bacilli 91061|Bacilli I phosphomevalonate kinase mvaK2 - 2.7.4.2 ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095 R03245 RC00002 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N BJHFPPGC_00046 435842.HMPREF0848_00192 1.77e-236 650.0 COG1304@1|root,COG1304@2|Bacteria,1TQZ3@1239|Firmicutes,4HAMV@91061|Bacilli 91061|Bacilli C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) fni GO:0003674,GO:0003824,GO:0004452,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0071704,GO:1901576 5.3.3.2 ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095,M00096,M00364,M00365,M00366,M00367 R01123 RC00455 ko00000,ko00001,ko00002,ko01000 - - - FMN_dh BJHFPPGC_00047 1046629.Ssal_01602 0.0 1669.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4HBQJ@91061|Bacilli 91061|Bacilli P COG0474 Cation transport ATPase mgtA - 3.6.3.2 ko:K01531 - - - - ko00000,ko01000 3.A.3.4 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase BJHFPPGC_00048 1046629.Ssal_01601 0.0 890.0 COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,4H9V5@91061|Bacilli 91061|Bacilli M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU GO:0000270,GO:0000271,GO:0003674,GO:0003824,GO:0003977,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0030203,GO:0033692,GO:0034637,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,Hexapep_2,NTP_transf_3,NTP_transferase BJHFPPGC_00049 1046629.Ssal_01599 2.04e-123 352.0 COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,4HII9@91061|Bacilli 91061|Bacilli L AdP-ribose pyrophosphatase nudF - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - iSB619.SA_RS07540,iYO844.BSU23610 NUDIX BJHFPPGC_00050 1046629.Ssal_01598 4.23e-41 136.0 2DC3Q@1|root,2ZCSA@2|Bacteria,1W5SW@1239|Firmicutes,4I23E@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_00051 1046629.Ssal_01597 4.74e-148 418.0 COG0775@1|root,COG0775@2|Bacteria,1U7WK@1239|Firmicutes,4HB8K@91061|Bacilli 91061|Bacilli E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively mtnN - 3.2.2.9 ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 M00034,M00609 R00194,R01401 RC00063,RC00318 ko00000,ko00001,ko00002,ko01000 - - - PNP_UDP_1 BJHFPPGC_00052 1046629.Ssal_01596 0.0 1535.0 COG3156@1|root,COG4932@1|root,COG3156@2|Bacteria,COG4932@2|Bacteria 2|Bacteria M domain protein - - - ko:K02460 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - Cna_B,Collagen_bind,FctA,Gram_pos_anchor,MucBP,SdrD_B,T2SSK,YSIRK_signal BJHFPPGC_00053 1046629.Ssal_01595 1.21e-242 666.0 COG0438@1|root,COG0438@2|Bacteria,1TPSS@1239|Firmicutes,4HBKA@91061|Bacilli 91061|Bacilli M Glycosyltransferase, group 1 family protein dgs - 2.4.1.208 ko:K13677 ko00561,ko01100,map00561,map01100 - R05164 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003 - GT4 - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 BJHFPPGC_00054 1046629.Ssal_01594 1.23e-315 860.0 COG0438@1|root,COG0438@2|Bacteria,1TPTA@1239|Firmicutes,4HA41@91061|Bacilli 91061|Bacilli M Glycosyltransferase, group 1 family protein pimB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006643,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046872,GO:0071704,GO:1901576 2.4.1.337 ko:K19002 ko00561,ko01100,map00561,map01100 - R10850 RC00005,RC00059 ko00000,ko00001,ko01000,ko01003 - GT4 - Glyco_transf_4,Glycos_transf_1 BJHFPPGC_00056 1046629.Ssal_01592 0.0 1294.0 COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,4HABZ@91061|Bacilli 91061|Bacilli J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD BJHFPPGC_00057 1046629.Ssal_01591 2.12e-200 557.0 COG0596@1|root,COG0596@2|Bacteria,1V202@1239|Firmicutes,4HJ0U@91061|Bacilli 91061|Bacilli S hydrolases or acyltransferases (alpha beta hydrolase superfamily) - GO:0003674,GO:0003824,GO:0016787 - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 BJHFPPGC_00058 904306.HMPREF9192_1302 3.77e-247 679.0 2DQ82@1|root,3357U@2|Bacteria,1VFZ3@1239|Firmicutes,4HNXV@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF3114) - - - - - - - - - - - - DUF3114 BJHFPPGC_00059 1046629.Ssal_01589 1.64e-39 130.0 COG1983@1|root,COG1983@2|Bacteria,1VKBQ@1239|Firmicutes,4HRGW@91061|Bacilli 91061|Bacilli KT PspC domain protein pspC - - - - - - - - - - - PspC BJHFPPGC_00060 435842.HMPREF0848_00209 4.11e-151 426.0 COG1272@1|root,COG1272@2|Bacteria,1TTA5@1239|Firmicutes,4HDYT@91061|Bacilli 91061|Bacilli K protein, Hemolysin III hly-III - - ko:K11068 - - - - ko00000,ko02042 - - - HlyIII BJHFPPGC_00061 1046629.Ssal_01586 1.08e-102 297.0 COG0789@1|root,COG0789@2|Bacteria,1V7Z4@1239|Firmicutes 1239|Firmicutes K hmm pf08876 - - - - - - - - - - - - DUF1836 BJHFPPGC_00062 904306.HMPREF9192_1306 6.73e-286 783.0 COG1257@1|root,COG1257@2|Bacteria,1TPNY@1239|Firmicutes,4HBQ3@91061|Bacilli 91061|Bacilli C Belongs to the HMG-CoA reductase family mvaA - 1.1.1.88,2.3.1.9 ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177,R02081 RC00004,RC00326,RC00644 ko00000,ko00001,ko00002,ko01000,ko04147 - - - HMG-CoA_red BJHFPPGC_00063 1046629.Ssal_01584 2.86e-267 733.0 COG3425@1|root,COG3425@2|Bacteria,1TR4K@1239|Firmicutes,4HA67@91061|Bacilli 91061|Bacilli I synthase mvaS - 2.3.3.10 ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 M00088,M00095 R01978 RC00004,RC00503 ko00000,ko00001,ko00002,ko01000 - - - HMG_CoA_synt_C,HMG_CoA_synt_N BJHFPPGC_00064 1046629.Ssal_01582 2.35e-210 580.0 COG0207@1|root,COG0207@2|Bacteria,1TSIR@1239|Firmicutes,4HI1C@91061|Bacilli 91061|Bacilli F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA - 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt BJHFPPGC_00065 1046629.Ssal_01581 3.16e-116 333.0 COG0262@1|root,COG0262@2|Bacteria,1VB80@1239|Firmicutes,4HIGJ@91061|Bacilli 91061|Bacilli H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis folA - 1.5.1.3 ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 ko00000,ko00001,ko00002,ko01000 - - - DHFR_1 BJHFPPGC_00066 435842.HMPREF0848_00215 2.97e-30 107.0 2DFKW@1|root,2ZS8U@2|Bacteria,1W5G0@1239|Firmicutes,4HZFD@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_00067 1046629.Ssal_01579 8.89e-288 786.0 COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,4H9U4@91061|Bacilli 91061|Bacilli O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP clpX GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - ko:K03544 ko04112,map04112 - - - ko00000,ko00001,ko03110 - - - AAA_2,ClpB_D2-small,zf-C4_ClpX BJHFPPGC_00068 1046629.Ssal_01578 9.58e-144 405.0 COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,4HBXZ@91061|Bacilli 91061|Bacilli D Necessary for normal cell division and for the maintenance of normal septation engB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K03978 - - - - ko00000,ko03036 - - - MMR_HSR1 BJHFPPGC_00069 1046629.Ssal_01577 0.0 877.0 COG0833@1|root,COG0833@2|Bacteria,1UHNR@1239|Firmicutes 1239|Firmicutes E amino acid lysP - - ko:K02205,ko:K03293,ko:K16235,ko:K16236 - - - - ko00000,ko02000 2.A.3.1,2.A.3.1.10 - iHN637.CLJU_RS13850 AA_permease BJHFPPGC_00070 1046629.Ssal_01576 1.48e-219 606.0 COG2040@1|root,COG2040@2|Bacteria,1UHQ5@1239|Firmicutes,4HAS6@91061|Bacilli 91061|Bacilli H Homocysteine mmuM - 2.1.1.10 ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 - R00650 RC00003,RC00035 ko00000,ko00001,ko01000 - - - S-methyl_trans BJHFPPGC_00071 1035184.HMPREF1042_0385 3.14e-42 139.0 2BXCI@1|root,346RD@2|Bacteria,1VYRT@1239|Firmicutes,4HYPP@91061|Bacilli,42DR8@671232|Streptococcus anginosus group 91061|Bacilli S Domain of unknown function (DUF1912) - - - - - - - - - - - - DUF1912 BJHFPPGC_00072 759913.SDSE_1678 1.19e-21 90.5 2DJ7H@1|root,304X7@2|Bacteria,1TXCP@1239|Firmicutes,4I6AH@91061|Bacilli,1M9TG@119603|Streptococcus dysgalactiae group 91061|Bacilli L Helix-hairpin-helix DNA-binding motif class 1 - - - - - - - - - - - - HHH_5 BJHFPPGC_00073 1046629.Ssal_01573 1.09e-140 398.0 COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,4HC55@91061|Bacilli 91061|Bacilli I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP plsY - 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - G3P_acyltransf BJHFPPGC_00074 1046629.Ssal_01572 0.0 1243.0 COG0187@1|root,COG0187@2|Bacteria,1TQCF@1239|Firmicutes,4H9UC@91061|Bacilli 91061|Bacilli L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parE GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 - ko:K02622 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim BJHFPPGC_00077 904306.HMPREF9192_1319 0.0 1567.0 COG0188@1|root,COG0188@2|Bacteria,1TRE7@1239|Firmicutes,4HAQB@91061|Bacilli 91061|Bacilli L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parC - - ko:K02621 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseA_C,DNA_topoisoIV BJHFPPGC_00078 1046629.Ssal_01567 2.9e-254 696.0 COG0115@1|root,COG0115@2|Bacteria,1TQQI@1239|Firmicutes,4HASX@91061|Bacilli 91061|Bacilli E Aminotransferase ilvE - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - iYO844.BSU38550 Aminotran_4 BJHFPPGC_00079 663952.SDD27957_05870 8.46e-23 89.7 2DJ75@1|root,304WQ@2|Bacteria,1TXBV@1239|Firmicutes,4I69J@91061|Bacilli,1M9R1@119603|Streptococcus dysgalactiae group 91061|Bacilli S Protein of unknown function (DUF2969) - - - - - - - - - - - - DUF2969 BJHFPPGC_00082 1046629.Ssal_01564 9.51e-268 736.0 COG0539@1|root,COG0539@2|Bacteria,1TQ9N@1239|Firmicutes,4H9PX@91061|Bacilli 91061|Bacilli J ribosomal protein S1 rpsA - - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 BJHFPPGC_00085 1046629.Ssal_01563 5.27e-140 396.0 2DMIQ@1|root,32RV1@2|Bacteria,1VGN9@1239|Firmicutes,4I0DZ@91061|Bacilli 91061|Bacilli S Domain of Unknown Function with PDB structure (DUF3862) - - - - - - - - - - - - DUF3862 BJHFPPGC_00086 1046629.Ssal_01562 4.59e-149 421.0 COG0398@1|root,COG0398@2|Bacteria 2|Bacteria M Pfam SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc BJHFPPGC_00087 435842.HMPREF0848_00231 1.31e-286 784.0 COG2348@1|root,COG2348@2|Bacteria,1V181@1239|Firmicutes,4HEVU@91061|Bacilli 91061|Bacilli V FemAB family murN - - ko:K12554 ko00550,ko01100,map00550,map01100 - R08780 RC00055,RC00064 ko00000,ko00001,ko01000,ko01011 - - - FemAB BJHFPPGC_00088 1046629.Ssal_01560 2.86e-219 606.0 COG0673@1|root,COG0673@2|Bacteria,1TQSS@1239|Firmicutes,4HDXF@91061|Bacilli 91061|Bacilli S oxidoreductase - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C BJHFPPGC_00089 1046629.Ssal_01559 2.23e-65 199.0 2EBZ8@1|root,335YI@2|Bacteria,1VFRS@1239|Firmicutes,4HNUK@91061|Bacilli 91061|Bacilli S Domain of unknown function (DUF1827) XK27_09445 - - - - - - - - - - - DUF1827 BJHFPPGC_00090 1046629.Ssal_01558 4.35e-108 311.0 COG0494@1|root,COG0494@2|Bacteria,1VH6Q@1239|Firmicutes,4HQVJ@91061|Bacilli 91061|Bacilli L Belongs to the Nudix hydrolase family XK27_09440 - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX BJHFPPGC_00091 904306.HMPREF9192_1333 0.0 1408.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HA0V@91061|Bacilli 91061|Bacilli O Belongs to the ClpA ClpB family clpE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03697 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,UVR BJHFPPGC_00092 1046629.Ssal_01556 2.4e-230 634.0 COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,4H9X8@91061|Bacilli 91061|Bacilli E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline argF - 2.1.3.3 ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844 R01398 RC00096 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N BJHFPPGC_00093 1046629.Ssal_01554 1.35e-46 149.0 COG4703@1|root,COG4703@2|Bacteria,1VKD0@1239|Firmicutes,4HRGC@91061|Bacilli 91061|Bacilli S protein conserved in bacteria ykuJ - - - - - - - - - - - DUF1797 BJHFPPGC_00094 1046629.Ssal_01553 1.27e-150 424.0 COG0765@1|root,COG0765@2|Bacteria,1TPM3@1239|Firmicutes,4IQKK@91061|Bacilli 91061|Bacilli P Binding-protein-dependent transport system inner membrane component - - - ko:K02029 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 BJHFPPGC_00095 1046629.Ssal_01552 7.38e-168 469.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli 91061|Bacilli E abc transporter atp-binding protein glnQ - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran BJHFPPGC_00096 904306.HMPREF9192_1338 1.01e-100 293.0 COG1918@1|root,COG1918@2|Bacteria,1VEHC@1239|Firmicutes,4HPFS@91061|Bacilli 91061|Bacilli P FeoA domain protein feoA - - ko:K04758 - - - - ko00000,ko02000 - - - FeoA BJHFPPGC_00097 1046629.Ssal_01549 0.0 1346.0 COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,4HBCS@91061|Bacilli 91061|Bacilli P transporter of a GTP-driven Fe(2 ) uptake system feoB - - ko:K04759 - - - - ko00000,ko02000 9.A.8.1 - iSB619.SA_RS13395 FeoB_C,FeoB_N,Gate BJHFPPGC_00098 759913.SDSE_1600 5.93e-13 62.8 2DJ8A@1|root,304YV@2|Bacteria,1TXF8@1239|Firmicutes,4I6DK@91061|Bacilli,1MA5P@119603|Streptococcus dysgalactiae group 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_00099 1046629.Ssal_01547 1.98e-188 523.0 COG2267@1|root,COG2267@2|Bacteria,1V37Y@1239|Firmicutes,4ITDD@91061|Bacilli 91061|Bacilli I Alpha/beta hydrolase family - - - - - - - - - - - - Hydrolase_4 BJHFPPGC_00100 904306.HMPREF9192_1342 9.07e-198 548.0 COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,4H9Q6@91061|Bacilli 91061|Bacilli F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - - THF_DHG_CYH,THF_DHG_CYH_C BJHFPPGC_00101 1046629.Ssal_01545 1.04e-184 515.0 COG0063@1|root,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,4HBZC@91061|Bacilli 91061|Bacilli H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD - 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N BJHFPPGC_00102 1046629.Ssal_01544 0.0 1289.0 COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,4HAFX@91061|Bacilli 91061|Bacilli M penicillin-binding protein pbp2b - - ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PBP_dimer,Transpeptidase BJHFPPGC_00103 1046629.Ssal_01543 1.07e-135 384.0 COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,4HAZR@91061|Bacilli 91061|Bacilli L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO recR - - ko:K06187 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecR,Toprim_4 BJHFPPGC_00104 1046629.Ssal_01542 2.35e-184 514.0 COG3711@1|root,COG3711@2|Bacteria,1TT5A@1239|Firmicutes,4HC5Y@91061|Bacilli 91061|Bacilli K antiterminator licT - - ko:K03488 - - - - ko00000,ko03000 - - - CAT_RBD,PRD BJHFPPGC_00105 1046629.Ssal_01541 3.1e-112 322.0 COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,4HIIE@91061|Bacilli 91061|Bacilli S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ybeY - - ko:K07042 - - - - ko00000,ko03009 - - - UPF0054 BJHFPPGC_00106 1046629.Ssal_01540 8.52e-86 253.0 COG0818@1|root,COG0818@2|Bacteria,1VEGR@1239|Firmicutes,4HNKN@91061|Bacilli 91061|Bacilli M Diacylglycerol kinase dgkA - 2.7.1.107,2.7.1.66 ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 - R02240,R05626 RC00002,RC00017 ko00000,ko00001,ko01000 - - iSB619.SA_RS07900 DAGK_prokar BJHFPPGC_00107 1046629.Ssal_01539 1.16e-212 587.0 COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,4H9WF@91061|Bacilli 91061|Bacilli M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism era GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - ko:K03595 - - - - ko00000,ko03009,ko03029 - - - KH_2,MMR_HSR1 BJHFPPGC_00108 1046629.Ssal_01536 3.14e-188 523.0 COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,4H9Q7@91061|Bacilli 91061|Bacilli L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates fpg - 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS BJHFPPGC_00109 1046629.Ssal_01535 5.59e-117 337.0 COG0237@1|root,COG0237@2|Bacteria,1V6FS@1239|Firmicutes,4HII3@91061|Bacilli 91061|Bacilli H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A coaE GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS08510 CoaE BJHFPPGC_00110 1046629.Ssal_01534 2.52e-282 773.0 COG0477@1|root,COG2814@2|Bacteria,1TRDJ@1239|Firmicutes,4H9Q9@91061|Bacilli 91061|Bacilli EGP Major Facilitator pmrA - - ko:K08161 - - - - ko00000,ko02000 2.A.1.2.20 - - MFS_1,MFS_1_like,Sugar_tr BJHFPPGC_00111 904306.HMPREF9192_1354 1.06e-44 145.0 COG1314@1|root,COG1314@2|Bacteria,1VEQR@1239|Firmicutes,4HNKC@91061|Bacilli 91061|Bacilli U Preprotein translocase subunit SecG secG GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0033036,GO:0034613,GO:0042886,GO:0043952,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944 - ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecG BJHFPPGC_00112 1046629.Ssal_01532 0.0 1573.0 COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,4HBBH@91061|Bacilli 91061|Bacilli J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - OB_RNB,RNB,S1 BJHFPPGC_00113 1046629.Ssal_01531 1.98e-105 304.0 COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,4HGZX@91061|Bacilli 91061|Bacilli O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA smpB GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070930,GO:0071704,GO:1901564 - ko:K03664 - - - - ko00000 - - - SmpB BJHFPPGC_00114 904306.HMPREF9192_1357 0.0 940.0 COG0561@1|root,COG0652@1|root,COG0561@2|Bacteria,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,4H9V0@91061|Bacilli 91061|Bacilli G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ppiB - 5.2.1.8 ko:K03768 - - - - ko00000,ko01000,ko03110 - - - Hydrolase_3,Pro_isomerase BJHFPPGC_00115 1046629.Ssal_01529 1.17e-84 249.0 COG1098@1|root,COG1098@2|Bacteria,1VASQ@1239|Firmicutes,4HKSW@91061|Bacilli 91061|Bacilli J RNA binding protein, contains ribosomal protein S1 domain yugI - - ko:K07570 - - - - ko00000 - - - S1 BJHFPPGC_00116 1046629.Ssal_01528 7.29e-247 679.0 COG0006@1|root,COG0006@2|Bacteria,1TQ6R@1239|Firmicutes,4HA5I@91061|Bacilli 91061|Bacilli E Belongs to the peptidase M24B family pepQ - 3.4.13.9 ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 BJHFPPGC_00117 1046629.Ssal_01526 3.69e-233 642.0 COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,4H9NG@91061|Bacilli 91061|Bacilli K Catabolite control protein A ccpA GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 BJHFPPGC_00118 1046629.Ssal_01525 1.05e-250 688.0 COG2315@1|root,COG2315@2|Bacteria,1V4K7@1239|Firmicutes,4HP2K@91061|Bacilli 91061|Bacilli S YjbR XK27_07735 - - - - - - - - - - - EVE,YjbR BJHFPPGC_00119 1046629.Ssal_01524 1.92e-245 676.0 COG1929@1|root,COG1929@2|Bacteria,1TPSI@1239|Firmicutes 1239|Firmicutes G Belongs to the glycerate kinase type-1 family glxK - 2.7.1.165 ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 - R08572 RC00002,RC00428 ko00000,ko00001,ko01000 - - - Gly_kinase BJHFPPGC_00120 1046629.Ssal_01522 5.72e-99 288.0 COG5506@1|root,COG5506@2|Bacteria,1VFCV@1239|Firmicutes,4HNNE@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF1694) XK27_05190 - - - - - - - - - - - DUF1694 BJHFPPGC_00121 1046629.Ssal_01521 6.13e-315 857.0 COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,4HAKI@91061|Bacilli 91061|Bacilli G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N BJHFPPGC_00122 646413.C5IUL7_9CAUD 1.71e-264 726.0 4QAQE@10239|Viruses,4QUYF@35237|dsDNA viruses no RNA stage,4QPDM@28883|Caudovirales,4QKN9@10699|Siphoviridae 10699|Siphoviridae S Phage integrase family - GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0015074,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - - - - - - - - - - - BJHFPPGC_00123 1122173.AXVL01000004_gene744 5.62e-38 135.0 2DF54@1|root,32U4N@2|Bacteria 2|Bacteria S Bacterial PH domain - - - - - - - - - - - - SHOCT,bPH_3 BJHFPPGC_00125 525379.HMPREF0819_0484 2.01e-26 101.0 2DKJ0@1|root,309N2@2|Bacteria,1VQMK@1239|Firmicutes,4I1ZB@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_00126 1051631.F8HGP8_9CAUD 2.76e-33 115.0 4QD8F@10239|Viruses,4QVUH@35237|dsDNA viruses no RNA stage,4QQPS@28883|Caudovirales,4QM2Q@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - BJHFPPGC_00128 1069534.LRC_07110 1.4e-92 280.0 COG3617@1|root,COG3645@1|root,COG3617@2|Bacteria,COG3645@2|Bacteria,1TPKA@1239|Firmicutes,4HDVT@91061|Bacilli,3FB3U@33958|Lactobacillaceae 91061|Bacilli K BRO family, N-terminal domain - - - ko:K07741 - - - - ko00000 - - - ANT,Bro-N,ORF6C BJHFPPGC_00129 1069533.Sinf_0769 9.34e-35 120.0 2ENNN@1|root,33GA0@2|Bacteria,1VN2K@1239|Firmicutes,4HR9I@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_00132 435842.HMPREF0848_00198 9.04e-93 315.0 COG4932@1|root,COG4932@2|Bacteria,1UXB4@1239|Firmicutes 1239|Firmicutes M Pilin isopeptide linkage domain protein - - - - - - - - - - - - Cna_B,Collagen_bind,FctA,Gram_pos_anchor,VWA,YSIRK_signal BJHFPPGC_00133 1123299.AUKZ01000018_gene209 1.64e-62 202.0 COG3935@1|root,COG3935@2|Bacteria,1UJ33@1239|Firmicutes,4HKZC@91061|Bacilli 91061|Bacilli L Replication initiation and membrane attachment - - - ko:K02086 - - - - ko00000 - - - DnaB_2,HTH_36 BJHFPPGC_00134 73422.L0P359_9CAUD 2.26e-170 477.0 4QBU2@10239|Viruses,4QV13@35237|dsDNA viruses no RNA stage,4QPH3@28883|Caudovirales,4QM65@10699|Siphoviridae 10699|Siphoviridae S IstB-like ATP binding protein - - - - - - - - - - - - - BJHFPPGC_00136 1214184.ALKY01000039_gene939 4.66e-100 300.0 COG3723@1|root,COG3723@2|Bacteria,1UNDF@1239|Firmicutes,4HB2T@91061|Bacilli 91061|Bacilli L Recombinational DNA repair protein (RecE pathway) recT - - ko:K07455 - - - - ko00000,ko03400 - - - RecT BJHFPPGC_00137 1214184.ALKY01000039_gene938 1.89e-126 367.0 COG1074@1|root,COG1074@2|Bacteria,1V1UQ@1239|Firmicutes,4HGSG@91061|Bacilli,1WTYI@1307|Streptococcus suis 91061|Bacilli L PDDEXK-like domain of unknown function (DUF3799) pi112 - - - - - - - - - - - DUF3799 BJHFPPGC_00138 646413.C5IUI2_9CAUD 1.42e-87 259.0 4QAU9@10239|Viruses,4QVR2@35237|dsDNA viruses no RNA stage,4QQV4@28883|Caudovirales,4QKUJ@10699|Siphoviridae 10699|Siphoviridae S Single-strand binding protein family - - - - - - - - - - - - - BJHFPPGC_00139 112023.Q9MCM0_9CAUD 9.76e-96 280.0 4QW7S@35237|dsDNA viruses no RNA stage,4QPK3@28883|Caudovirales,4QKQC@10699|Siphoviridae 10699|Siphoviridae S magnesium ion binding - - - - - - - - - - - - - BJHFPPGC_00141 1123309.AQYB01000014_gene918 1.75e-16 72.4 2BK0S@1|root,32EDT@2|Bacteria,1TZGK@1239|Firmicutes,4HSJ1@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_00145 306323.Q56S64_9CAUD 2.53e-64 199.0 4QAQV@10239|Viruses,4QUPK@35237|dsDNA viruses no RNA stage,4QPCB@28883|Caudovirales,4QKM5@10699|Siphoviridae 10699|Siphoviridae S sequence-specific DNA binding - - - - - - - - - - - - - BJHFPPGC_00146 120574.Q94M66_9CAUD 1.41e-189 534.0 4QAIJ@10239|Viruses,4QVZ9@35237|dsDNA viruses no RNA stage,4QPXI@28883|Caudovirales,4QM02@10699|Siphoviridae 10699|Siphoviridae S C-5 cytosine-specific DNA methylase - - - - - - - - - - - - - BJHFPPGC_00149 1403946.Q615_SPAC00127G0144 4.55e-46 154.0 2DPRG@1|root,3333C@2|Bacteria,1VJNE@1239|Firmicutes,4HPDS@91061|Bacilli 91061|Bacilli S Transcriptional regulator, ArpU family arpU - - - - - - - - - - - - BJHFPPGC_00150 764299.STRIC_2128 3.77e-65 202.0 COG3728@1|root,COG3728@2|Bacteria,1VAD9@1239|Firmicutes,4HPEP@91061|Bacilli 91061|Bacilli L Terminase small subunit - - - ko:K07474 - - - - ko00000 - - - Terminase_2 BJHFPPGC_00151 1069533.Sinf_0783 7.45e-259 715.0 COG1783@1|root,COG1783@2|Bacteria,1TRQP@1239|Firmicutes,4HDMY@91061|Bacilli 91061|Bacilli L Phage terminase, large subunit yqaT - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C BJHFPPGC_00152 1069533.Sinf_0784 6.51e-312 855.0 2DB9U@1|root,2Z7Z6@2|Bacteria,1TR67@1239|Firmicutes,4HAC8@91061|Bacilli 91061|Bacilli S Phage portal protein, SPP1 family - - - - - - - - - - - - Phage_prot_Gp6 BJHFPPGC_00153 413066.A1EAE3_9CAUD 3.51e-157 456.0 4QC5Z@10239|Viruses,4QUNP@35237|dsDNA viruses no RNA stage,4QPGX@28883|Caudovirales,4QKMB@10699|Siphoviridae 10699|Siphoviridae S Phage Mu protein F like protein - GO:0005575,GO:0019012,GO:0019028,GO:0044423,GO:0046729 - - - - - - - - - - - BJHFPPGC_00155 1069533.Sinf_0788 2.27e-197 550.0 COG4653@1|root,COG4653@2|Bacteria,1UZMZ@1239|Firmicutes,4HBKI@91061|Bacilli 91061|Bacilli S Phage capsid family - - - - - - - - - - - - Phage_capsid BJHFPPGC_00156 35344.A0A097PBF3_BPT12 1.01e-14 70.5 4QB93@10239|Viruses,4QWE4@35237|dsDNA viruses no RNA stage,4QU9K@28883|Caudovirales 28883|Caudovirales S DNA-dependent transcription, termination - - - - - - - - - - - - - BJHFPPGC_00157 413066.A1EAF1_9CAUD 1.85e-46 152.0 4QBCW@10239|Viruses,4QUN6@35237|dsDNA viruses no RNA stage,4QPS7@28883|Caudovirales,4QKNA@10699|Siphoviridae 10699|Siphoviridae S Phage gp6-like head-tail connector protein - - - - - - - - - - - - - BJHFPPGC_00158 1069533.Sinf_0791 1.19e-29 108.0 28QAG@1|root,2ZCT2@2|Bacteria,1W1YZ@1239|Firmicutes,4HZS0@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_00159 1069533.Sinf_0792 3.34e-26 101.0 2A78R@1|root,30W57@2|Bacteria,1VQMH@1239|Firmicutes,4HSPS@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_00161 764299.STRIC_2145 2e-61 195.0 2C4D6@1|root,3455M@2|Bacteria,1VYTU@1239|Firmicutes,4HYIZ@91061|Bacilli 91061|Bacilli S Phage tail tube protein - - - - - - - - - - - - Phage_tail_2 BJHFPPGC_00164 413066.A1EAB0_9CAUD 1.17e-109 370.0 4QAK6@10239|Viruses,4QZP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - GO:0008150,GO:0016032,GO:0019058,GO:0019068,GO:0044403,GO:0044419,GO:0051704,GO:0098003 - - - - - - - - - - - BJHFPPGC_00165 413066.A1EAB1_9CAUD 1.17e-99 298.0 4QBF8@10239|Viruses,4QUS7@35237|dsDNA viruses no RNA stage,4QPI9@28883|Caudovirales,4QKN2@10699|Siphoviridae 10699|Siphoviridae S Phage tail protein - - - - - - - - - - - - - BJHFPPGC_00166 413066.A1EAB2_9CAUD 2.44e-198 629.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019058,GO:0019062,GO:0022610,GO:0044403,GO:0044406,GO:0044419,GO:0044423,GO:0044650,GO:0051704,GO:0098015,GO:0098024 - - - - - - - - - - - BJHFPPGC_00169 1051631.F8HGP0_9CAUD 8.66e-88 259.0 4QBDC@10239|Viruses,4QVEM@35237|dsDNA viruses no RNA stage,4QQ6A@28883|Caudovirales 28883|Caudovirales S Pfam:Phage_holin_4_1 - GO:0005575,GO:0018995,GO:0033643,GO:0033644,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279 - - - - - - - - - - - BJHFPPGC_00170 888049.HMPREF8578_0250 2.1e-32 114.0 COG5546@1|root,COG5546@2|Bacteria,1VGGV@1239|Firmicutes,4HPNN@91061|Bacilli 91061|Bacilli S COG5546 Small integral membrane protein hol - - - - - - - - - - - Phage_holin_1 BJHFPPGC_00174 1069533.Sinf_0802 4.12e-138 397.0 COG0791@1|root,COG0791@2|Bacteria,1VT9V@1239|Firmicutes,4HV77@91061|Bacilli 91061|Bacilli M Bacteriophage peptidoglycan hydrolase - - - - - - - - - - - - Amidase_5 BJHFPPGC_00176 1046629.Ssal_01520 4.48e-34 117.0 2FKS5@1|root,34CCP@2|Bacteria,1W67C@1239|Firmicutes 1239|Firmicutes - - WQ51_00785 - - - - - - - - - - - - BJHFPPGC_00177 1046629.Ssal_01519 0.0 1378.0 COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,4H9S0@91061|Bacilli 91061|Bacilli M Belongs to the LTA synthase family ltaS GO:0005575,GO:0005576 2.7.8.20 ko:K19005 ko00561,ko01100,map00561,map01100 - R05081,R10849 RC00017 ko00000,ko00001,ko01000 - - - Sulfatase BJHFPPGC_00178 1046629.Ssal_01518 3.14e-275 753.0 COG1092@1|root,COG1092@2|Bacteria,1TRAJ@1239|Firmicutes,4HAA1@91061|Bacilli 91061|Bacilli J Methyltransferase ywbD - 2.1.1.191 ko:K06969 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_SAM BJHFPPGC_00179 904306.HMPREF9192_1372 5e-152 428.0 COG0710@1|root,COG0710@2|Bacteria,1VHVX@1239|Firmicutes,4IPJP@91061|Bacilli 91061|Bacilli E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate aroD - 4.2.1.10 ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03084 RC00848 ko00000,ko00001,ko00002,ko01000 - - - DHquinase_I BJHFPPGC_00180 904306.HMPREF9192_1373 5.91e-199 551.0 COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,4HD4R@91061|Bacilli 91061|Bacilli E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) aroE GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - - Shikimate_dh_N BJHFPPGC_00181 1046629.Ssal_01515 2.4e-256 702.0 COG0337@1|root,COG0337@2|Bacteria,1TPKZ@1239|Firmicutes,4HAKN@91061|Bacilli 91061|Bacilli E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) aroB - 4.2.3.4 ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03083 RC00847 ko00000,ko00001,ko00002,ko01000 - - - DHQ_synthase BJHFPPGC_00182 904306.HMPREF9192_1375 1.83e-279 764.0 COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,4HA0H@91061|Bacilli 91061|Bacilli E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system aroC GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 - - - Chorismate_synt BJHFPPGC_00183 904306.HMPREF9192_1376 1.52e-261 717.0 COG0287@1|root,COG0287@2|Bacteria,1TPXG@1239|Firmicutes,4HBI4@91061|Bacilli 91061|Bacilli E prephenate dehydrogenase tyrA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12 ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00025 R01728 RC00125 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU22610 ACT,PDH BJHFPPGC_00184 1046629.Ssal_01512 2.99e-71 214.0 COG3679@1|root,COG3679@2|Bacteria,1VASS@1239|Firmicutes,4HPJM@91061|Bacilli 91061|Bacilli S Belongs to the UPF0342 family XK26_04240 - - - - - - - - - - - Com_YlbF BJHFPPGC_00185 904306.HMPREF9192_1378 8.19e-217 599.0 COG0039@1|root,COG0039@2|Bacteria,1UXY2@1239|Firmicutes,4HD1S@91061|Bacilli 91061|Bacilli C Belongs to the LDH MDH superfamily hicD2 - 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 - R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N BJHFPPGC_00186 1046629.Ssal_01510 6.91e-297 811.0 COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,4HBHZ@91061|Bacilli 91061|Bacilli E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate aroA GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 - - - EPSP_synthase BJHFPPGC_00187 904306.HMPREF9192_1380 5.37e-112 322.0 COG0703@1|root,COG0703@2|Bacteria,1VA6Z@1239|Firmicutes,4HKD6@91061|Bacilli 91061|Bacilli F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate aroK GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - SKI BJHFPPGC_00188 1046629.Ssal_01508 1.99e-196 544.0 COG0077@1|root,COG0077@2|Bacteria,1TPDN@1239|Firmicutes,4HA96@91061|Bacilli 91061|Bacilli E Prephenate dehydratase pheA GO:0003674,GO:0003824,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 4.2.1.51 ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024 R00691,R01373 RC00360 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU27900 ACT,PDT BJHFPPGC_00189 904306.HMPREF9192_1382 0.0 867.0 COG1316@1|root,COG1316@2|Bacteria,1TSWQ@1239|Firmicutes,4HE66@91061|Bacilli 91061|Bacilli K Transcriptional regulator msrR - - - - - - - - - - - LytR_cpsA_psr BJHFPPGC_00190 264199.stu0650 3.01e-129 377.0 COG1275@1|root,COG1275@2|Bacteria,1UYTE@1239|Firmicutes,4HGBI@91061|Bacilli 91061|Bacilli P C4-dicarboxylate transporter malic acid transport ydiA - - ko:K11041 ko05150,map05150 - - - ko00000,ko00001,ko02042 2.A.16 - - SLAC1 BJHFPPGC_00191 904306.HMPREF9192_1384 8.7e-222 615.0 COG1960@1|root,COG1960@2|Bacteria,1UYHK@1239|Firmicutes,4HCT5@91061|Bacilli 91061|Bacilli I acyl-CoA dehydrogenase - - - - - - - - - - - - Acyl-CoA_dh_N BJHFPPGC_00192 1046629.Ssal_01496 3.67e-126 359.0 COG2128@1|root,COG2128@2|Bacteria 2|Bacteria S hydroperoxide reductase activity mip - - - - - - - - - - - CMD BJHFPPGC_00193 904306.HMPREF9192_1386 0.0 872.0 COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli 91061|Bacilli J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family rumA - 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - TRAM,tRNA_U5-meth_tr BJHFPPGC_00194 1354300.AUQY01000005_gene87 1.3e-69 210.0 COG3070@1|root,COG3070@2|Bacteria,1V42M@1239|Firmicutes,24JNV@186801|Clostridia,22IPD@1570339|Peptoniphilaceae 186801|Clostridia K TfoX N-terminal domain - - - - - - - - - - - - TfoX_N BJHFPPGC_00195 936596.HMPREF1495_1854 3.84e-24 96.3 COG1073@1|root,COG1073@2|Bacteria,1U9AI@1239|Firmicutes,24B6Z@186801|Clostridia 186801|Clostridia K Psort location Cytoplasmic, score 8.87 - - - ko:K06889 - - - - ko00000 - - - Hydrolase_4 BJHFPPGC_00196 411489.CLOL250_02700 1.32e-84 251.0 COG0454@1|root,COG0456@2|Bacteria,1V3IC@1239|Firmicutes,24HK5@186801|Clostridia,36JMS@31979|Clostridiaceae 186801|Clostridia K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - - - - - - - - - - Acetyltransf_10,Acetyltransf_7 BJHFPPGC_00197 638301.HMPREF0444_1312 2.87e-126 360.0 2DBDH@1|root,2Z8KQ@2|Bacteria,1V2YZ@1239|Firmicutes,4HK4W@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_00199 1316408.HSISM1_1075 6.16e-145 409.0 COG1309@1|root,COG1309@2|Bacteria,1V27S@1239|Firmicutes,4HGFC@91061|Bacilli 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N BJHFPPGC_00200 1316408.HSISM1_1076 1.99e-157 443.0 COG1277@1|root,2Z9TS@2|Bacteria,1TPNJ@1239|Firmicutes,4HGY0@91061|Bacilli 91061|Bacilli S ABC-type transport system involved in multi-copper enzyme maturation, permease component - - - - - - - - - - - - ABC2_membrane_4 BJHFPPGC_00201 888833.HMPREF9421_1191 2.04e-166 466.0 COG1131@1|root,COG1131@2|Bacteria,1V1H1@1239|Firmicutes,4IQ0H@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran BJHFPPGC_00202 999425.HMPREF9186_00280 0.0 1019.0 COG1132@1|root,COG1132@2|Bacteria,1TSRV@1239|Firmicutes,4HD39@91061|Bacilli 91061|Bacilli V ABC transporter transmembrane region - - - - - - - - - - - - ABC_membrane,ABC_tran BJHFPPGC_00203 1046629.Ssal_01491 5.58e-60 185.0 2FAP6@1|root,342WU@2|Bacteria,1VX2X@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - BJHFPPGC_00204 1046629.Ssal_01490 1.64e-73 220.0 2DVV7@1|root,33XC5@2|Bacteria 2|Bacteria S ParE toxin of type II toxin-antitoxin system, parDE - - - - - - - - - - - - ParE_toxin BJHFPPGC_00205 1046629.Ssal_01480 3.9e-170 476.0 COG0596@1|root,COG0596@2|Bacteria,1UMWY@1239|Firmicutes 1239|Firmicutes S hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6,Hydrolase_4 BJHFPPGC_00206 1316408.HSISM1_1088 7.97e-168 469.0 COG4221@1|root,COG4221@2|Bacteria,1V0BE@1239|Firmicutes,4HDZJ@91061|Bacilli 91061|Bacilli S Domain of unknown function (DUF4336) - - - - - - - - - - - - DUF4336 BJHFPPGC_00207 904306.HMPREF9192_1446 2.99e-254 700.0 COG2807@1|root,COG2807@2|Bacteria,1TP9R@1239|Firmicutes,4H9YZ@91061|Bacilli 91061|Bacilli P transporter yycB - - ko:K03449 - - - - ko00000,ko02000 2.A.1.17 - - MFS_1 BJHFPPGC_00208 904306.HMPREF9192_1447 1.18e-191 533.0 COG1307@1|root,COG1307@2|Bacteria,1V229@1239|Firmicutes,4IPK5@91061|Bacilli 91061|Bacilli S EDD domain protein, DegV family ChZ00x2 - - - - - - - - - - - DegV BJHFPPGC_00209 1046629.Ssal_01477 5.71e-125 357.0 COG1309@1|root,COG1309@2|Bacteria,1VGCX@1239|Firmicutes,4HRBM@91061|Bacilli 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N BJHFPPGC_00210 1114965.Spaf_1286 1.08e-124 356.0 COG1418@1|root,COG1418@2|Bacteria,1V7IZ@1239|Firmicutes,4HIVB@91061|Bacilli 91061|Bacilli F HD superfamily hydrolase yagB - - ko:K06950 - - - - ko00000 - - - HD BJHFPPGC_00211 888833.HMPREF9421_1585 3.59e-167 471.0 COG1266@1|root,COG1266@2|Bacteria,1V1I8@1239|Firmicutes 1239|Firmicutes S CAAX amino terminal protease family - - - ko:K07052 - - - - ko00000 - - - Abi BJHFPPGC_00212 1046629.Ssal_01475 2.12e-137 390.0 COG3142@1|root,COG3142@2|Bacteria,1V3V5@1239|Firmicutes,4HCVQ@91061|Bacilli 91061|Bacilli P Participates in the control of copper homeostasis cutC - - ko:K06201 - - - - ko00000 - - - CutC BJHFPPGC_00215 1127131.WEISSC39_08120 4.43e-19 90.5 2DMBI@1|root,32H42@2|Bacteria,1VFT3@1239|Firmicutes,4HK1A@91061|Bacilli 91061|Bacilli S Domain of unknown function (DUF4767) yjdB - - - - - - - - - - - DUF4767 BJHFPPGC_00216 1046629.Ssal_01468 5.66e-194 538.0 28KEH@1|root,2ZA0R@2|Bacteria 2|Bacteria S Domain of unknown function (DUF4300) - - - - - - - - - - - - DUF4300 BJHFPPGC_00217 435842.HMPREF0848_00308 4.95e-148 420.0 COG1266@1|root,COG1266@2|Bacteria 2|Bacteria V CAAX protease self-immunity - - - - - - - - - - - - Abi BJHFPPGC_00218 435842.HMPREF0848_00309 2.03e-217 603.0 COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,4HAUK@91061|Bacilli 91061|Bacilli P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily fecD - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD BJHFPPGC_00219 435842.HMPREF0848_00310 2.77e-171 479.0 COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,4HETN@91061|Bacilli 91061|Bacilli HP ABC transporter fecE - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran BJHFPPGC_00220 435842.HMPREF0848_00311 1.82e-231 638.0 COG0614@1|root,COG0614@2|Bacteria,1TSDG@1239|Firmicutes,4HDG3@91061|Bacilli 91061|Bacilli P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component fatB - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 BJHFPPGC_00221 435842.HMPREF0848_00312 2.66e-159 447.0 COG2819@1|root,COG2819@2|Bacteria,1V2YF@1239|Firmicutes,4IQ46@91061|Bacilli 91061|Bacilli S Putative esterase - - - - - - - - - - - - Esterase BJHFPPGC_00222 1069533.Sinf_1920 1.7e-202 561.0 COG1597@1|root,COG1597@2|Bacteria,1TQ9A@1239|Firmicutes 1239|Firmicutes I Diacylglycerol kinase yegS - - - - - - - - - - - DAGK_cat BJHFPPGC_00223 1069533.Sinf_1921 4.98e-219 607.0 COG1808@1|root,COG1808@2|Bacteria,1TRFZ@1239|Firmicutes,4HCVP@91061|Bacilli 91061|Bacilli S Domain of unknown function (DUF389) - - - - - - - - - - - - DUF389 BJHFPPGC_00224 562981.HMPREF0428_01670 1.55e-42 139.0 COG2261@1|root,COG2261@2|Bacteria,1VENK@1239|Firmicutes,4HNKV@91061|Bacilli 91061|Bacilli S Membrane ytgB - - - - - - - - - - - Transgly_assoc BJHFPPGC_00225 638301.HMPREF0444_0929 3.71e-31 110.0 COG3237@1|root,COG3237@2|Bacteria,1VGX4@1239|Firmicutes,4HY48@91061|Bacilli 91061|Bacilli S CsbD-like - - - - - - - - - - - - CsbD BJHFPPGC_00226 1123300.AUIN01000017_gene643 3.77e-216 609.0 COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4H9Z5@91061|Bacilli 91061|Bacilli C Dehydrogenase pdhD - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim BJHFPPGC_00227 888816.HMPREF9389_1676 5.03e-211 588.0 COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,4HBEA@91061|Bacilli,1WQRY@1305|Streptococcus sanguinis 91061|Bacilli C Acetoin dehydrogenase E1 component subunit alpha acoA - - ko:K21416 - - - - ko00000,ko01000 - - - E1_dh BJHFPPGC_00228 388919.SSA_1139 5.3e-222 615.0 COG0022@1|root,COG0022@2|Bacteria,1TP3J@1239|Firmicutes,4HAP6@91061|Bacilli,1WR3E@1305|Streptococcus sanguinis 91061|Bacilli C dehydrogenase E1 component acoB - - ko:K21417 - - - - ko00000,ko01000 - - - Transket_pyr,Transketolase_C BJHFPPGC_00229 699248.SRA_06236 3.79e-179 512.0 COG0508@1|root,COG0508@2|Bacteria,1TR5N@1239|Firmicutes,4HDFT@91061|Bacilli 91061|Bacilli C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex acoC - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding BJHFPPGC_00230 1316408.HSISM1_1770 2.41e-106 310.0 COG0500@1|root,COG0500@2|Bacteria,1UI83@1239|Firmicutes,4HHCN@91061|Bacilli 91061|Bacilli Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 BJHFPPGC_00231 1123300.AUIN01000009_gene228 2.73e-95 282.0 COG1309@1|root,COG1309@2|Bacteria,1VCGN@1239|Firmicutes,4HMEM@91061|Bacilli 91061|Bacilli K TetR family transcriptional regulator - - - - - - - - - - - - TetR_N BJHFPPGC_00232 435842.HMPREF0848_00313 8.63e-60 185.0 2CUT8@1|root,32SW2@2|Bacteria,1VAQK@1239|Firmicutes,4HNH7@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_00233 435842.HMPREF0848_00314 6.46e-158 445.0 COG1266@1|root,COG1266@2|Bacteria 2|Bacteria V CAAX protease self-immunity - - - - - - - - - - - - Abi BJHFPPGC_00235 1005705.HMPREF9967_0252 1.93e-31 116.0 2DIXF@1|root,304BM@2|Bacteria,1TWG1@1239|Firmicutes,4I59C@91061|Bacilli,43G59@68892|Streptococcus infantis 91061|Bacilli M Bacterial lipoprotein - - - - - - - - - - - - DUF3642 BJHFPPGC_00236 435842.HMPREF0848_00317 1.32e-78 234.0 COG3272@1|root,COG3272@2|Bacteria,1VGGK@1239|Firmicutes,4HP7S@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF1722) - - - - - - - - - - - - DUF1722 BJHFPPGC_00237 1046629.Ssal_01457 6.81e-83 244.0 2AK1X@1|root,31ARI@2|Bacteria,1V717@1239|Firmicutes,4HIQ9@91061|Bacilli 91061|Bacilli S Pyrimidine dimer DNA glycosylase yqeB - - - - - - - - - - - Pyr_excise BJHFPPGC_00239 1046629.Ssal_01455 8.79e-67 203.0 2FBVV@1|root,3440F@2|Bacteria,1VZAT@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - BJHFPPGC_00240 1046629.Ssal_01454 2.25e-119 343.0 COG1266@1|root,COG1266@2|Bacteria,1VBYM@1239|Firmicutes,4HM2K@91061|Bacilli 91061|Bacilli S CAAX protease self-immunity - - - - - - - - - - - - Abi BJHFPPGC_00241 1046629.Ssal_01453 9.77e-144 406.0 COG2755@1|root,COG2755@2|Bacteria,1V1CQ@1239|Firmicutes,4HGVZ@91061|Bacilli 91061|Bacilli E GDSL-like Lipase/Acylhydrolase - - - - - - - - - - - - Lipase_GDSL_2 BJHFPPGC_00242 1046629.Ssal_01451 1.05e-129 370.0 2F636@1|root,33YMH@2|Bacteria,1VYAW@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - BJHFPPGC_00243 1046629.Ssal_01450 0.0 999.0 COG0659@1|root,COG0659@2|Bacteria,1TPI4@1239|Firmicutes,4H9V4@91061|Bacilli 91061|Bacilli P Sulfate permease and related transporters (MFS superfamily) yvdB GO:0003333,GO:0003674,GO:0005215,GO:0005310,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008272,GO:0008509,GO:0008514,GO:0015075,GO:0015103,GO:0015116,GO:0015138,GO:0015141,GO:0015171,GO:0015172,GO:0015179,GO:0015183,GO:0015238,GO:0015318,GO:0015556,GO:0015698,GO:0015711,GO:0015740,GO:0015741,GO:0015744,GO:0015800,GO:0015807,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070778,GO:0071422,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0098656,GO:0098660,GO:0098661,GO:1901682,GO:1902358,GO:1902475,GO:1903825,GO:1905039 - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp BJHFPPGC_00244 904306.HMPREF9192_1125 2.4e-191 531.0 COG3689@1|root,COG3689@2|Bacteria,1V3EX@1239|Firmicutes,4HGMG@91061|Bacilli 91061|Bacilli S TIGR03943 family XK27_03010 - - ko:K08986 - - - - ko00000 - - - DUF1980 BJHFPPGC_00245 1046629.Ssal_01448 3.26e-199 553.0 COG0701@1|root,COG0701@2|Bacteria,1TQHK@1239|Firmicutes,4HB25@91061|Bacilli 91061|Bacilli S permease XK27_03015 - - ko:K07089 - - - - ko00000 - - - ArsP_1 BJHFPPGC_00247 904306.HMPREF9192_1128 0.0 1329.0 COG2183@1|root,COG2183@2|Bacteria,1TPFE@1239|Firmicutes,4HAGY@91061|Bacilli 91061|Bacilli K Transcriptional accessory protein tex - - ko:K06959 - - - - ko00000 - - - HHH_3,S1,Tex_N,Tex_YqgF BJHFPPGC_00248 1046629.Ssal_01444 1.02e-55 173.0 COG1983@1|root,COG1983@2|Bacteria,1VF0M@1239|Firmicutes,4IRAN@91061|Bacilli 91061|Bacilli KT PspC domain WQ51_05770 - - - - - - - - - - - PspC BJHFPPGC_00249 1046629.Ssal_01443 3.21e-215 595.0 COG1493@1|root,COG1493@2|Bacteria,1TP5Z@1239|Firmicutes,4HAXR@91061|Bacilli 91061|Bacilli F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion hprK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K06023 - - - - ko00000,ko01000 - - - Hpr_kinase_C,Hpr_kinase_N BJHFPPGC_00250 1046629.Ssal_01442 4.85e-187 520.0 COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,4HAT0@91061|Bacilli 91061|Bacilli M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt - - ko:K13292 - - - - ko00000,ko01000 - - - LGT BJHFPPGC_00251 904306.HMPREF9192_1133 9.98e-28 106.0 COG4768@1|root,COG4768@2|Bacteria,1VAXN@1239|Firmicutes,4HM93@91061|Bacilli 91061|Bacilli S protein containing a divergent version of the methyl-accepting chemotaxis-like domain ytxG - - - - - - - - - - - DUF948 BJHFPPGC_00252 1046629.Ssal_01439 3.91e-90 265.0 COG4980@1|root,COG4980@2|Bacteria,1VFY7@1239|Firmicutes,4HNWV@91061|Bacilli 91061|Bacilli S General stress protein ytxH - - - - - - - - - - - YtxH BJHFPPGC_00254 1046629.Ssal_01437 8.33e-227 624.0 COG0826@1|root,COG0826@2|Bacteria,1TQIZ@1239|Firmicutes,4HA2T@91061|Bacilli 91061|Bacilli O Peptidase U32 yrrN - - ko:K08303 ko05120,map05120 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_U32 BJHFPPGC_00255 904306.HMPREF9192_1140 0.0 872.0 COG0826@1|root,COG0826@2|Bacteria,1TPRE@1239|Firmicutes,4HBEG@91061|Bacilli 91061|Bacilli O Peptidase U32 yrrO - - ko:K08303 ko05120,map05120 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_U32,Peptidase_U32_C BJHFPPGC_00256 1046629.Ssal_01434 1.8e-111 322.0 COG1268@1|root,COG1268@2|Bacteria,1VA1G@1239|Firmicutes,4HNE8@91061|Bacilli 91061|Bacilli S biotin synthase bioY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03523 ko02010,map02010 M00581,M00582 - - ko00000,ko00001,ko00002,ko02000 2.A.88.1,2.A.88.2 - - BioY BJHFPPGC_00258 264199.stu0676 2.97e-45 145.0 COG4443@1|root,COG4443@2|Bacteria,1VEFE@1239|Firmicutes,4HNSP@91061|Bacilli 91061|Bacilli S protein conserved in bacteria XK27_12190 - - - - - - - - - - - PC4 BJHFPPGC_00259 1046629.Ssal_01431 1.09e-293 805.0 COG1914@1|root,COG1914@2|Bacteria,1TPT1@1239|Firmicutes,4HAEA@91061|Bacilli 91061|Bacilli P H( )-stimulated, divalent metal cation uptake system mntH - - ko:K03322 - - - - ko00000,ko02000 2.A.55.2.6,2.A.55.3 - - Nramp BJHFPPGC_00260 888821.HMPREF9394_0792 5.9e-18 79.0 29RMD@1|root,30CQM@2|Bacteria,1UA84@1239|Firmicutes,4IKJF@91061|Bacilli,1WRWU@1305|Streptococcus sanguinis 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_00262 435842.HMPREF0848_00346 0.0 983.0 COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,4H9X4@91061|Bacilli 91061|Bacilli J Belongs to the class-II aminoacyl-tRNA synthetase family lysS - 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon BJHFPPGC_00263 1046629.Ssal_01428 5.42e-209 589.0 COG1388@1|root,COG1388@2|Bacteria 2|Bacteria M LysM domain - - - - - - - - - - - - LysM,Transglycosylas BJHFPPGC_00264 904293.HMPREF9176_0571 1.73e-36 130.0 2BXK6@1|root,33WGZ@2|Bacteria,1VVCA@1239|Firmicutes,4HWEI@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_00265 1046629.Ssal_01424 3.26e-224 617.0 COG1011@1|root,COG1011@2|Bacteria,1V5P7@1239|Firmicutes,4HHGY@91061|Bacilli 91061|Bacilli S hydrolase - - - ko:K07025 - - - - ko00000 - - - HAD_2 BJHFPPGC_00266 904306.HMPREF9192_1153 2.41e-148 417.0 COG0406@1|root,COG0406@2|Bacteria,1V7EZ@1239|Firmicutes,4HJCK@91061|Bacilli 91061|Bacilli G Phosphoglycerate mutase pgm - - - - - - - - - - - His_Phos_1 BJHFPPGC_00267 1046629.Ssal_01422 1.23e-105 305.0 COG2606@1|root,COG2606@2|Bacteria,1V6JF@1239|Firmicutes,4HIH1@91061|Bacilli 91061|Bacilli S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily - - - ko:K03976 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit BJHFPPGC_00268 904306.HMPREF9192_1155 8.19e-193 537.0 COG3757@1|root,COG3757@2|Bacteria,1V2YH@1239|Firmicutes,4HI8U@91061|Bacilli 91061|Bacilli M Glycosyl hydrolase, family 25 - - 3.5.1.28 ko:K01447,ko:K07273 - - R04112 RC00064,RC00141 ko00000,ko01000 - - - Glyco_hydro_25 BJHFPPGC_00269 1123304.AQYA01000028_gene1720 3.25e-35 125.0 COG2461@1|root,COG2461@2|Bacteria 2|Bacteria P Hemerythrin HHE cation binding domain protein - - - - - - - - - - - - PAS_10 BJHFPPGC_00270 1046629.Ssal_01419 1.03e-201 558.0 COG0561@1|root,COG0561@2|Bacteria,1UFDJ@1239|Firmicutes,4HDIH@91061|Bacilli 91061|Bacilli G hydrolase hmpP2 - - - - - - - - - - - Hydrolase_3 BJHFPPGC_00271 1046629.Ssal_01418 2.07e-147 415.0 COG2141@1|root,COG2141@2|Bacteria,1VJRB@1239|Firmicutes,4ISN7@91061|Bacilli 91061|Bacilli C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - - - - - - - - - - - BJHFPPGC_00272 1046629.Ssal_01417 1.73e-269 738.0 COG1073@1|root,COG1073@2|Bacteria,1VEWD@1239|Firmicutes,4IQU0@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF2974) - - - - - - - - - - - - DUF2974 BJHFPPGC_00273 904306.HMPREF9192_1161 4.25e-170 476.0 COG4221@1|root,COG4221@2|Bacteria,1V08N@1239|Firmicutes,4IPTJ@91061|Bacilli 91061|Bacilli S Belongs to the short-chain dehydrogenases reductases (SDR) family sdh - - - - - - - - - - - adh_short BJHFPPGC_00274 888048.HMPREF8577_0102 9.92e-58 180.0 COG1694@1|root,COG1694@2|Bacteria,1VA3E@1239|Firmicutes,4HKDQ@91061|Bacilli 91061|Bacilli S Nucleotide pyrophosphohydrolase - - - - - - - - - - - - MazG-like BJHFPPGC_00275 1346.DQ08_04855 6.12e-235 665.0 COG3410@1|root,COG3410@2|Bacteria,1TPQU@1239|Firmicutes,4HBI0@91061|Bacilli 91061|Bacilli L Uncharacterized conserved protein (DUF2075) - - - ko:K09384 - - - - ko00000 - - - DUF2075,GIY-YIG BJHFPPGC_00276 1046629.Ssal_01404 6.78e-188 525.0 COG5464@1|root,COG5464@2|Bacteria 2|Bacteria S double-stranded DNA endodeoxyribonuclease activity - - - - - - - - - - - - PDDEXK_2 BJHFPPGC_00277 1046629.Ssal_01404 2.2e-24 99.4 COG5464@1|root,COG5464@2|Bacteria 2|Bacteria S double-stranded DNA endodeoxyribonuclease activity - - - - - - - - - - - - PDDEXK_2 BJHFPPGC_00278 1046629.Ssal_01404 1.36e-15 76.3 COG5464@1|root,COG5464@2|Bacteria 2|Bacteria S double-stranded DNA endodeoxyribonuclease activity - - - - - - - - - - - - PDDEXK_2 BJHFPPGC_00279 1046629.Ssal_01403 0.0 1238.0 COG5373@1|root,COG5434@1|root,COG5373@2|Bacteria,COG5434@2|Bacteria,1W0JP@1239|Firmicutes 1239|Firmicutes M Right handed beta helix region - - - - - - - - - - - - Beta_helix,Pectate_lyase_3 BJHFPPGC_00280 1046629.Ssal_01403 3.61e-76 257.0 COG5373@1|root,COG5434@1|root,COG5373@2|Bacteria,COG5434@2|Bacteria,1W0JP@1239|Firmicutes 1239|Firmicutes M Right handed beta helix region - - - - - - - - - - - - Beta_helix,Pectate_lyase_3 BJHFPPGC_00281 1046629.Ssal_01401 4.67e-234 644.0 COG2169@1|root,COG2169@2|Bacteria,1TR37@1239|Firmicutes,4HK9Z@91061|Bacilli 91061|Bacilli F DNA RNA non-specific endonuclease spd - - ko:K15051 - - - - ko00000 - - - Endonuclea_NS_2 BJHFPPGC_00282 435842.HMPREF0848_00371 4.21e-118 339.0 COG1704@1|root,COG1704@2|Bacteria,1V1G7@1239|Firmicutes,4IR1J@91061|Bacilli 91061|Bacilli S LemA family lemA - - ko:K03744 - - - - ko00000 - - - LemA BJHFPPGC_00283 904306.HMPREF9192_1176 1.4e-188 526.0 COG0501@1|root,COG0501@2|Bacteria,1TP23@1239|Firmicutes,4HB11@91061|Bacilli 91061|Bacilli O Belongs to the peptidase M48B family htpX - - ko:K03799 - M00743 - - ko00000,ko00002,ko01000,ko01002 - - - Peptidase_M48 BJHFPPGC_00284 1046629.Ssal_01398 1.19e-145 411.0 COG1321@1|root,COG1321@2|Bacteria,1V4V7@1239|Firmicutes,4HHV4@91061|Bacilli 91061|Bacilli K iron dependent repressor sirR - - ko:K03709 - - - - ko00000,ko03000 - - - Fe_dep_repr_C,Fe_dep_repress,FeoA BJHFPPGC_00285 1046629.Ssal_01397 1.13e-219 606.0 COG0803@1|root,COG0803@2|Bacteria,1TRKU@1239|Firmicutes,4HAKT@91061|Bacilli 91061|Bacilli P Belongs to the bacterial solute-binding protein 9 family psaA - - ko:K11704,ko:K19971,ko:K19975,ko:K19976 ko02010,map02010 M00318,M00791,M00792 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.14,3.A.1.15.15,3.A.1.15.2,3.A.1.15.6 - - ZnuA BJHFPPGC_00286 1046629.Ssal_01396 3.37e-170 478.0 COG1108@1|root,COG1108@2|Bacteria,1TPZB@1239|Firmicutes,4HBD7@91061|Bacilli 91061|Bacilli P ABC-type Mn2 Zn2 transport systems, permease components mtsC GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0010035,GO:0010038,GO:0010043,GO:0016020,GO:0042221,GO:0044464,GO:0050896,GO:0071944 - ko:K11705,ko:K19972,ko:K19976 ko02010,map02010 M00318,M00791,M00792 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.14,3.A.1.15.15,3.A.1.15.2,3.A.1.15.6 - - ABC-3 BJHFPPGC_00287 1046629.Ssal_01395 9.65e-163 456.0 COG1121@1|root,COG1121@2|Bacteria,1TQJ3@1239|Firmicutes,4HA2W@91061|Bacilli 91061|Bacilli P ABC transporter, ATP-binding protein sitB - 3.6.3.35 ko:K02074,ko:K09820,ko:K10830,ko:K11706,ko:K19973 ko02010,map02010 M00243,M00244,M00318,M00791,M00792 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15,3.A.1.15.14,3.A.1.15.15,3.A.1.15.2,3.A.1.15.6 - - ABC_tran BJHFPPGC_00288 1046629.Ssal_01394 4.98e-96 281.0 COG4720@1|root,COG4720@2|Bacteria,1V5GD@1239|Firmicutes,4HI8Y@91061|Bacilli 91061|Bacilli S Psort location CytoplasmicMembrane, score - - - ko:K16927 - M00582 - - ko00000,ko00002,ko02000 3.A.1.32 - - ECF-ribofla_trS,ECF_trnsprt BJHFPPGC_00289 1046629.Ssal_01392 3.24e-84 249.0 2DNM7@1|root,32Y2X@2|Bacteria,1VF26@1239|Firmicutes,4HP82@91061|Bacilli 91061|Bacilli S Domain of unknown function (DUF4430) - - - - - - - - - - - - DUF4430 BJHFPPGC_00290 1046629.Ssal_01391 0.0 1811.0 COG2352@1|root,COG2352@2|Bacteria,1TQB6@1239|Firmicutes,4HCAF@91061|Bacilli 91061|Bacilli H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle ppc GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00168,M00170,M00171,M00172,M00173,M00346,M00374 R00345 RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPcase BJHFPPGC_00291 1046629.Ssal_01390 5.41e-233 642.0 COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,4HBB4@91061|Bacilli 91061|Bacilli L DNA polymerase III delta subunit holA - 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta BJHFPPGC_00292 1046629.Ssal_01389 2.63e-142 401.0 COG0605@1|root,COG0605@2|Bacteria,1TPXT@1239|Firmicutes,4HA6U@91061|Bacilli 91061|Bacilli C radicals which are normally produced within the cells and which are toxic to biological systems sodA GO:0005575,GO:0005576 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 - - - ko00000,ko00001,ko01000 - - - Sod_Fe_C,Sod_Fe_N BJHFPPGC_00293 322159.STER_0765 7.69e-249 692.0 COG2367@1|root,COG2367@2|Bacteria,1VHF8@1239|Firmicutes,4HU1N@91061|Bacilli 91061|Bacilli V D-alanyl-D-alanine carboxypeptidase - - - - - - - - - - - - Beta-lactamase2 BJHFPPGC_00294 1046629.Ssal_01387 7.46e-130 371.0 COG1989@1|root,COG1989@2|Bacteria,1TQY4@1239|Firmicutes,4HCC3@91061|Bacilli 91061|Bacilli NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases comC - 3.4.23.43 ko:K02236,ko:K02654 - M00331,M00429 - - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 3.A.15.2 - - DiS_P_DiS,Peptidase_A24 BJHFPPGC_00295 1046629.Ssal_01386 8.39e-114 327.0 COG0783@1|root,COG0783@2|Bacteria,1VCVJ@1239|Firmicutes,4HMBD@91061|Bacilli 91061|Bacilli P Belongs to the Dps family dps - - ko:K04047 - - - - ko00000,ko03036 - - - Ferritin BJHFPPGC_00296 1046629.Ssal_01385 8.12e-103 298.0 COG0735@1|root,COG0735@2|Bacteria,1V400@1239|Firmicutes,4HHF8@91061|Bacilli 91061|Bacilli P Belongs to the Fur family perR - - ko:K03711,ko:K09825 - - - - ko00000,ko03000 - - - FUR BJHFPPGC_00297 435842.HMPREF0848_00386 7.59e-37 124.0 COG4483@1|root,COG4483@2|Bacteria,1VK83@1239|Firmicutes,4HRG2@91061|Bacilli 91061|Bacilli S protein conserved in bacteria yqgQ - - - - - - - - - - - DUF910 BJHFPPGC_00298 1046629.Ssal_01383 2.67e-225 621.0 COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,4HBAU@91061|Bacilli 91061|Bacilli G Glucokinase glcK GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0051156,GO:0071704,GO:1901135 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS07790 ROK BJHFPPGC_00299 1046629.Ssal_01382 0.0 1191.0 COG1217@1|root,COG1217@2|Bacteria,1TQ5Y@1239|Firmicutes,4HAQ6@91061|Bacilli 91061|Bacilli T GTP-binding protein TypA typA - - ko:K06207 - - - - ko00000 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2 BJHFPPGC_00300 663952.SDD27957_07710 3.66e-12 63.5 2DJ77@1|root,304WT@2|Bacteria,1TXC0@1239|Firmicutes,4I69V@91061|Bacilli,1M9RX@119603|Streptococcus dysgalactiae group 91061|Bacilli S Protein of unknown function (DUF3165) - - - - - - - - - - - - DUF3165 BJHFPPGC_00301 1046629.Ssal_01380 7.48e-315 858.0 COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,4HA5P@91061|Bacilli 91061|Bacilli M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD - 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M BJHFPPGC_00302 1046629.Ssal_01379 1.5e-255 701.0 COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,4HBAQ@91061|Bacilli 91061|Bacilli M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG - 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 - Glyco_tran_28_C,Glyco_transf_28 BJHFPPGC_00303 904306.HMPREF9192_1192 2.1e-185 525.0 COG1589@1|root,COG1589@2|Bacteria,1VHEY@1239|Firmicutes 1239|Firmicutes D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex divIB - - ko:K03589 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - FtsQ,POTRA_1 BJHFPPGC_00304 1046629.Ssal_01377 5.77e-291 799.0 COG0849@1|root,COG0849@2|Bacteria,1TP1Z@1239|Firmicutes,4H9NF@91061|Bacilli 91061|Bacilli D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring ftsA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032153,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0098552,GO:0098562 - ko:K03590 ko04112,map04112 - - - ko00000,ko00001,ko03036,ko04812 - - - DUF3484,FtsA,SHS2_FTSA BJHFPPGC_00305 1046629.Ssal_01376 1.2e-299 819.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,4H9WZ@91061|Bacilli 91061|Bacilli D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity ftsZ GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030428,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin BJHFPPGC_00306 1046629.Ssal_01375 6.34e-156 438.0 COG0325@1|root,COG0325@2|Bacteria,1TRDN@1239|Firmicutes,4HC45@91061|Bacilli 91061|Bacilli S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis ylmE GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - ko:K06997 - - - - ko00000 - - - Ala_racemase_N BJHFPPGC_00307 1046629.Ssal_01374 6.09e-114 329.0 COG1799@1|root,COG1799@2|Bacteria 2|Bacteria D cell septum assembly sepF GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0022402,GO:0022607,GO:0032506,GO:0042802,GO:0044085,GO:0044464,GO:0051301,GO:0071840,GO:0071944,GO:0090529 - ko:K09772 - - - - ko00000,ko03036 - - - SepF BJHFPPGC_00308 435842.HMPREF0848_00397 1.95e-41 137.0 COG0762@1|root,COG0762@2|Bacteria 2|Bacteria D integral membrane protein yggT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02221 - - - - ko00000,ko02044 - - - YGGT BJHFPPGC_00309 1046629.Ssal_01373 2.18e-176 493.0 COG2302@1|root,COG2302@2|Bacteria,1U5V2@1239|Firmicutes,4HD3F@91061|Bacilli 91061|Bacilli S conserved protein, contains S4-like domain ylmH - - - - - - - - - - - S4 BJHFPPGC_00310 1046629.Ssal_01372 3.37e-192 535.0 COG3599@1|root,COG3599@2|Bacteria,1V27M@1239|Firmicutes,4HG80@91061|Bacilli 91061|Bacilli D Cell division initiation protein divIVA GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K04074 - - - - ko00000,ko03036 - - - DivIVA BJHFPPGC_00311 1046629.Ssal_01371 0.0 1848.0 COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,4HAWB@91061|Bacilli 91061|Bacilli J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS BJHFPPGC_00312 1046629.Ssal_01369 2.61e-235 646.0 COG0208@1|root,COG0208@2|Bacteria,1TQTH@1239|Firmicutes,4H9WX@91061|Bacilli 91061|Bacilli F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdF - 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - iSB619.SA_RS03915,iYO844.BSU17390 Ribonuc_red_sm BJHFPPGC_00313 1046629.Ssal_01368 0.0 1429.0 COG0209@1|root,COG0209@2|Bacteria,1TPFH@1239|Firmicutes,4H9X0@91061|Bacilli 91061|Bacilli F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdE - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - iYO844.BSU17380 RNR_N,Ribonuc_red_lgC,Ribonuc_red_lgN BJHFPPGC_00314 264199.stu1269 5.6e-45 145.0 COG0695@1|root,COG0695@2|Bacteria,1VEFX@1239|Firmicutes,4HNUX@91061|Bacilli 91061|Bacilli O Glutaredoxin nrdH - - ko:K06191 - - - - ko00000 - - - Glutaredoxin BJHFPPGC_00315 1046629.Ssal_01366 0.0 1737.0 COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,4HB5N@91061|Bacilli 91061|Bacilli C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate acnA GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C BJHFPPGC_00316 1046629.Ssal_01365 1.85e-265 727.0 COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,4H9YE@91061|Bacilli 91061|Bacilli C Belongs to the citrate synthase family citZ - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt BJHFPPGC_00317 1046629.Ssal_01364 1.15e-279 764.0 COG0538@1|root,COG0538@2|Bacteria,1UHPE@1239|Firmicutes,4H9US@91061|Bacilli 91061|Bacilli C Isocitrate dehydrogenase icd - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh BJHFPPGC_00318 1046629.Ssal_01363 2.72e-51 162.0 COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,4HKGA@91061|Bacilli 91061|Bacilli G phosphocarrier protein Hpr ptsH GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0043610,GO:0044424,GO:0044464,GO:0050789,GO:0065007 - ko:K11189 - - - - ko00000,ko02000 4.A.2.1 - - PTS-HPr BJHFPPGC_00319 1046629.Ssal_01362 0.0 1098.0 COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,4H9VD@91061|Bacilli 91061|Bacilli G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) ptsI GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0051179,GO:0051234,GO:0071702 2.7.3.9 ko:K08483 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 8.A.7 - - PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C BJHFPPGC_00320 1046629.Ssal_01360 0.0 919.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli 91061|Bacilli C Belongs to the aldehyde dehydrogenase family gapN GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0043891,GO:0047100,GO:0055114 1.2.1.9 ko:K00131 ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200 M00308,M00633 R01058 RC00242 ko00000,ko00001,ko00002,ko01000 - - - Aldedh BJHFPPGC_00321 1046629.Ssal_01359 1.25e-204 565.0 COG2819@1|root,COG2819@2|Bacteria,1UZZZ@1239|Firmicutes,4HCWE@91061|Bacilli 91061|Bacilli S Putative esterase XK27_05670 - - ko:K07017 - - - - ko00000 - - - Esterase BJHFPPGC_00322 1046629.Ssal_01358 4.54e-197 543.0 COG4947@1|root,COG4947@2|Bacteria,1TSKW@1239|Firmicutes,4HB4B@91061|Bacilli 91061|Bacilli S Esterase XK27_05675 - - - - - - - - - - - Esterase BJHFPPGC_00323 1046629.Ssal_01357 2.85e-287 783.0 COG1181@1|root,COG1181@2|Bacteria,1UIK5@1239|Firmicutes,4HBFS@91061|Bacilli 91061|Bacilli M carbamoylphosphate synthase large subunit XK27_05680 - - - - - - - - - - - ATP-grasp_4,CPSase_L_D2 BJHFPPGC_00324 1046629.Ssal_01356 5.91e-239 659.0 COG0513@1|root,COG0513@2|Bacteria,1TQ9R@1239|Firmicutes,4HANR@91061|Bacilli 91061|Bacilli L DEAD DEAH box helicase yfmL GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - - - - - - - - - - DEAD,Helicase_C BJHFPPGC_00325 1046629.Ssal_01355 5.27e-147 414.0 COG0572@1|root,COG0572@2|Bacteria,1TQ4V@1239|Firmicutes,4HAVR@91061|Bacilli 91061|Bacilli F Cytidine monophosphokinase udk GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PRK BJHFPPGC_00326 435842.HMPREF0848_00416 0.0 1161.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HBVV@91061|Bacilli 91061|Bacilli S abc transporter atp-binding protein ydiF - - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn BJHFPPGC_00327 435842.HMPREF0848_00417 7.55e-53 166.0 COG4298@1|root,COG4298@2|Bacteria,1VCHF@1239|Firmicutes,4HMAW@91061|Bacilli 91061|Bacilli S yiaA/B two helix domain - - - - - - - - - - - - YiaAB BJHFPPGC_00328 1046629.Ssal_01352 3.15e-171 478.0 COG0596@1|root,COG0596@2|Bacteria,1V02M@1239|Firmicutes,4HN2K@91061|Bacilli 91061|Bacilli S Alpha beta hydrolase - - 1.11.1.10 ko:K00433 - - - - ko00000,ko01000 - - - Abhydrolase_1,Hydrolase_4 BJHFPPGC_00329 1046629.Ssal_01351 0.0 1605.0 COG0392@1|root,COG2898@1|root,COG0392@2|Bacteria,COG2898@2|Bacteria,1TQI2@1239|Firmicutes,4HBHU@91061|Bacilli 91061|Bacilli J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms mprF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.2.3 ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00726 - - ko00000,ko00001,ko00002,ko01000,ko01504 2.A.1.3.37 - iYO844.BG12900 DUF2156,LPG_synthase_TM BJHFPPGC_00330 1046629.Ssal_01350 4.68e-189 525.0 COG3442@1|root,COG3442@2|Bacteria,1U7I9@1239|Firmicutes,4HD1P@91061|Bacilli 91061|Bacilli S glutamine amidotransferase cobQ - - ko:K07009 - - - - ko00000 - - - GATase_3 BJHFPPGC_00331 1046629.Ssal_01349 0.0 878.0 COG0771@1|root,COG0771@2|Bacteria,1UHPI@1239|Firmicutes,4HVP0@91061|Bacilli 91061|Bacilli M Mur ligase, middle domain protein murE2 - 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - DUF1727,Mur_ligase_M BJHFPPGC_00332 904306.HMPREF9192_1521 1.33e-157 445.0 COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,4H9XZ@91061|Bacilli 91061|Bacilli S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria dacA GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009975,GO:0016020,GO:0016021,GO:0016829,GO:0016849,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 2.7.7.85 ko:K18672 - - - - ko00000,ko01000 - - - DisA_N BJHFPPGC_00333 1046629.Ssal_01347 3.03e-210 583.0 COG4856@1|root,COG4856@2|Bacteria,1TSIV@1239|Firmicutes,4HD8Y@91061|Bacilli 91061|Bacilli S Protein conserved in bacteria ybbR GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009 - - - - - - - - - - YbbR BJHFPPGC_00334 1046629.Ssal_01346 2.77e-316 862.0 COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,4HB16@91061|Bacilli 91061|Bacilli G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate glmM - 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 - R02060 RC00408 ko00000,ko00001,ko01000 - - iSB619.SA_RS11275 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV BJHFPPGC_00335 1046629.Ssal_01345 6.85e-82 244.0 COG2246@1|root,COG2246@2|Bacteria,1VMS6@1239|Firmicutes,4HNB7@91061|Bacilli 91061|Bacilli S GtrA-like protein mesH - - - - - - - - - - - GtrA BJHFPPGC_00336 1046629.Ssal_01344 4.12e-157 441.0 COG2384@1|root,COG2384@2|Bacteria,1V3I4@1239|Firmicutes,4HHIM@91061|Bacilli 91061|Bacilli S SAM-dependent methyltransferase trmK GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.217 ko:K06967 - - - - ko00000,ko01000,ko03016 - - - TrmK BJHFPPGC_00337 1046629.Ssal_01343 2.91e-183 510.0 COG0327@1|root,COG0327@2|Bacteria,1TQ27@1239|Firmicutes,4H9NY@91061|Bacilli 91061|Bacilli S Belongs to the GTP cyclohydrolase I type 2 NIF3 family yqfO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - - - - - - - - - - NIF3 BJHFPPGC_00338 1046629.Ssal_01342 2.01e-181 506.0 COG0428@1|root,COG0428@2|Bacteria,1TP7J@1239|Firmicutes,4HB3R@91061|Bacilli 91061|Bacilli P Mediates zinc uptake. May also transport other divalent cations zupT - - ko:K07238 - - - - ko00000,ko02000 2.A.5.5 - - Zip BJHFPPGC_00339 1046629.Ssal_01341 1.42e-247 681.0 COG0665@1|root,COG0665@2|Bacteria,1TQTF@1239|Firmicutes,4HA0F@91061|Bacilli 91061|Bacilli E oxidoreductase yurR - 1.4.5.1 ko:K00285 ko00360,map00360 - R01374,R09493 RC00006,RC00025 ko00000,ko00001,ko01000 - - - DAO BJHFPPGC_00340 1046629.Ssal_01340 0.0 884.0 COG4099@1|root,COG4099@2|Bacteria,1TRER@1239|Firmicutes,4IQ64@91061|Bacilli 91061|Bacilli S phospholipase Carboxylesterase - - - - - - - - - - - - Esterase_phd,Peptidase_S9 BJHFPPGC_00341 1046629.Ssal_01339 7.83e-206 569.0 COG1209@1|root,COG1209@2|Bacteria,1V301@1239|Firmicutes,4H9R0@91061|Bacilli 91061|Bacilli M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis rfbA - 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase BJHFPPGC_00342 1046629.Ssal_01338 1.86e-140 396.0 COG1898@1|root,COG1898@2|Bacteria,1TRVB@1239|Firmicutes,4HFQB@91061|Bacilli 91061|Bacilli M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose rmlC - 5.1.3.13 ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R06514 RC01531 ko00000,ko00001,ko00002,ko01000 - - - dTDP_sugar_isom BJHFPPGC_00343 435842.HMPREF0848_00434 3.86e-263 719.0 COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,4HA3Y@91061|Bacilli 91061|Bacilli M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily rfbB GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0071704,GO:1901576 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd BJHFPPGC_00346 435842.HMPREF0848_00437 1.05e-273 748.0 COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,4HA60@91061|Bacilli 91061|Bacilli H Involved in the biosynthesis of porphyrin-containing compound hemN GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - - - - - - - - - - HemN_C,Radical_SAM BJHFPPGC_00347 1046629.Ssal_01331 3.56e-181 503.0 COG3884@1|root,COG3884@2|Bacteria,1V3RB@1239|Firmicutes,4HHJ4@91061|Bacilli 91061|Bacilli I Acyl-ACP thioesterase fat - 3.1.2.21 ko:K01071 ko00061,ko01100,map00061,map01100 - R04014,R08157,R08158 RC00014,RC00039 ko00000,ko00001,ko01000,ko01004 - - - Acyl-ACP_TE BJHFPPGC_00348 1046629.Ssal_01330 7.4e-179 498.0 COG0647@1|root,COG0647@2|Bacteria,1TQGM@1239|Firmicutes,4HA3R@91061|Bacilli 91061|Bacilli G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro nagD - 3.1.3.41 ko:K01101 ko00627,ko01120,map00627,map01120 - R03024 RC00151 ko00000,ko00001,ko01000 - - - Hydrolase_6,Hydrolase_like BJHFPPGC_00349 435842.HMPREF0848_00440 3.59e-150 422.0 COG4478@1|root,COG4478@2|Bacteria,1VGZ1@1239|Firmicutes,4HNTM@91061|Bacilli 91061|Bacilli S tigr01906 - - - - - - - - - - - - DUF1461 BJHFPPGC_00350 904306.HMPREF9192_1539 1.69e-174 486.0 COG1387@1|root,COG1387@2|Bacteria,1V77D@1239|Firmicutes,4HGYX@91061|Bacilli 91061|Bacilli E Histidinol phosphatase and related hydrolases of the PHP family hisJ - 3.1.3.15 ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03013 RC00017 ko00000,ko00001,ko00002,ko01000 - - - - BJHFPPGC_00351 435842.HMPREF0848_00448 1.13e-198 553.0 COG4632@1|root,COG4632@2|Bacteria,1TR6Z@1239|Firmicutes,4HGB0@91061|Bacilli 91061|Bacilli G Exopolysaccharide biosynthesis protein XK27_08080 - - - - - - - - - - - NAGPA BJHFPPGC_00352 435842.HMPREF0848_00449 1.28e-76 229.0 2EJUK@1|root,33DJ8@2|Bacteria,1VM50@1239|Firmicutes 1239|Firmicutes - - XK27_08085 - - - - - - - - - - - - BJHFPPGC_00353 435842.HMPREF0848_00450 1.26e-244 672.0 COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,4HA1H@91061|Bacilli 91061|Bacilli E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 BJHFPPGC_00354 435842.HMPREF0848_00451 5.04e-232 639.0 COG3705@1|root,COG3705@2|Bacteria,1TPZZ@1239|Firmicutes,4HBBA@91061|Bacilli 91061|Bacilli E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine hisZ - - ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002 - - - tRNA-synt_His BJHFPPGC_00355 435842.HMPREF0848_00452 2.81e-149 420.0 COG0040@1|root,COG0040@2|Bacteria,1TSVZ@1239|Firmicutes,4H9MH@91061|Bacilli 91061|Bacilli E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity hisG GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002,ko01000 - - - HisG,tRNA-synt_His BJHFPPGC_00356 1046629.Ssal_01322 2.93e-298 815.0 COG0141@1|root,COG0141@2|Bacteria,1TPAW@1239|Firmicutes,4H9XK@91061|Bacilli 91061|Bacilli E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine hisD GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU34910 Histidinol_dh BJHFPPGC_00357 435842.HMPREF0848_00454 3.35e-137 388.0 COG0131@1|root,COG0131@2|Bacteria,1TRH7@1239|Firmicutes,4HCFG@91061|Bacilli 91061|Bacilli E imidazoleglycerol-phosphate dehydratase hisB GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03457 RC00932 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS14130 IGPD BJHFPPGC_00358 435842.HMPREF0848_00455 8.15e-142 400.0 COG0118@1|root,COG0118@2|Bacteria,1TQT0@1239|Firmicutes,4HHNQ@91061|Bacilli 91061|Bacilli E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR hisH - - ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - GATase BJHFPPGC_00359 1046629.Ssal_01319 1.68e-166 466.0 COG0106@1|root,COG0106@2|Bacteria,1V1IR@1239|Firmicutes,4HACP@91061|Bacilli 91061|Bacilli E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase hisA GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth BJHFPPGC_00360 435842.HMPREF0848_00457 9.34e-175 488.0 COG0107@1|root,COG0107@2|Bacteria,1TP0W@1239|Firmicutes,4HAAM@91061|Bacilli 91061|Bacilli E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit hisF GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS14115 His_biosynth BJHFPPGC_00361 435842.HMPREF0848_00458 3.48e-79 234.0 COG0139@1|root,COG0139@2|Bacteria,1UYNA@1239|Firmicutes,4HA9R@91061|Bacilli 91061|Bacilli E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP hisI - 3.5.4.19,3.6.1.31 ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037 RC00002,RC01055 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS14110,iYO844.BSU34860 PRA-CH,PRA-PH BJHFPPGC_00362 1046629.Ssal_01315 1.27e-66 202.0 COG0140@1|root,COG0140@2|Bacteria 2|Bacteria E phosphoribosyl-ATP diphosphatase activity hisE GO:0000105,GO:0000287,GO:0003674,GO:0003824,GO:0004636,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052803,GO:0071704,GO:0071944,GO:0075136,GO:0075139,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.6.1.31,5.3.1.16 ko:K01523,ko:K01814,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037,R04640 RC00002,RC00945,RC01055 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS14110,iYO844.BSU34860 PRA-CH,PRA-PH BJHFPPGC_00364 904306.HMPREF9192_1546 8.89e-131 374.0 COG1285@1|root,COG1285@2|Bacteria,1V1GI@1239|Firmicutes 1239|Firmicutes S Psort location CytoplasmicMembrane, score XK27_05505 - - - - - - - - - - - DUF4956 BJHFPPGC_00365 435842.HMPREF0848_00461 1.19e-185 516.0 COG5036@1|root,COG5036@2|Bacteria,1V1FZ@1239|Firmicutes,4HJFI@91061|Bacilli 91061|Bacilli P molecular chaperone - - - - - - - - - - - - VTC BJHFPPGC_00366 435842.HMPREF0848_00468 5.48e-160 464.0 arCOG08054@1|root,2Z8AD@2|Bacteria,1TZ8N@1239|Firmicutes,4HV65@91061|Bacilli 91061|Bacilli S Carbohydrate-binding domain-containing protein Cthe_2159 - - - - - - - - - - - - Cthe_2159 BJHFPPGC_00367 904306.HMPREF9192_1549 8.86e-224 619.0 COG1216@1|root,COG2246@1|root,COG1216@2|Bacteria,COG2246@2|Bacteria,1UIHV@1239|Firmicutes,4ISID@91061|Bacilli 91061|Bacilli M glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2,GtrA BJHFPPGC_00368 435842.HMPREF0848_00470 0.0 2632.0 COG0366@1|root,COG5263@1|root,COG0366@2|Bacteria,COG5263@2|Bacteria,1VQXK@1239|Firmicutes,4HEIA@91061|Bacilli 91061|Bacilli M KxYKxGKxW signal domain protein - - 2.4.1.5 ko:K00689 ko00500,ko02020,map00500,map02020 - R02120,R06066 RC00028 ko00000,ko00001,ko01000 - GH13 - Big_2,CW_binding_1,Glyco_hydro_70 BJHFPPGC_00369 435842.HMPREF0848_00471 0.0 2664.0 COG0366@1|root,COG5263@1|root,COG0366@2|Bacteria,COG5263@2|Bacteria,1VQXK@1239|Firmicutes,4HEIA@91061|Bacilli 91061|Bacilli M KxYKxGKxW signal domain protein - - 2.4.1.5 ko:K00689 ko00500,ko02020,map00500,map02020 - R02120,R06066 RC00028 ko00000,ko00001,ko01000 - GH13 - Big_2,CW_binding_1,Glyco_hydro_70 BJHFPPGC_00370 435842.HMPREF0848_01445 1.89e-130 380.0 COG3547@1|root,COG3547@2|Bacteria,1TPSP@1239|Firmicutes,4IPIG@91061|Bacilli 91061|Bacilli L COG3547 Transposase and inactivated derivatives - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 BJHFPPGC_00371 904306.HMPREF9192_0883 3.9e-71 224.0 COG3547@1|root,COG3547@2|Bacteria,1TR6E@1239|Firmicutes,4HCAZ@91061|Bacilli 91061|Bacilli L transposase IS116 IS110 IS902 family - - - - - - - - - - - - DEDD_Tnp_IS110,Nop,Transposase_20 BJHFPPGC_00372 435842.HMPREF0848_01445 2.73e-18 82.8 COG3547@1|root,COG3547@2|Bacteria,1TPSP@1239|Firmicutes,4IPIG@91061|Bacilli 91061|Bacilli L COG3547 Transposase and inactivated derivatives - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 BJHFPPGC_00373 1000588.HMPREF9965_0157 1.17e-52 177.0 COG1619@1|root,COG4095@1|root,COG1619@2|Bacteria,COG4095@2|Bacteria,1TRBB@1239|Firmicutes,4HDUZ@91061|Bacilli,2TNTZ@28037|Streptococcus mitis 91061|Bacilli V LD-carboxypeptidase mccF - - - - - - - - - - - Peptidase_S66 BJHFPPGC_00374 1215915.BN193_04685 2.21e-207 579.0 COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4HAXJ@91061|Bacilli,1YC6N@1357|Lactococcus 91061|Bacilli L High confidence in function and specificity B4168_4126 - - ko:K07493 - - - - ko00000 - - - Transposase_mut BJHFPPGC_00375 1046629.Ssal_01307 0.0 2945.0 COG0366@1|root,COG5263@1|root,COG0366@2|Bacteria,COG5263@2|Bacteria,1VQXK@1239|Firmicutes,4HEIA@91061|Bacilli 91061|Bacilli M KxYKxGKxW signal domain protein - - 2.4.1.5 ko:K00689 ko00500,ko02020,map00500,map02020 - R02120,R06066 RC00028 ko00000,ko00001,ko01000 - GH13 - Big_2,CW_binding_1,Glyco_hydro_70 BJHFPPGC_00376 904306.HMPREF9192_1554 1.11e-292 805.0 COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,4HAV4@91061|Bacilli 91061|Bacilli D Belongs to the SEDS family rodA - - ko:K05837 - - - - ko00000,ko03036 - - - FTSW_RODA_SPOVE BJHFPPGC_00377 1046629.Ssal_01305 6.98e-304 830.0 COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,4HACA@91061|Bacilli 91061|Bacilli S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043021,GO:0043022,GO:0044424,GO:0044464,GO:0044877 - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 BJHFPPGC_00378 904306.HMPREF9192_1556 4.84e-144 407.0 COG4468@1|root,COG4468@2|Bacteria,1VY8D@1239|Firmicutes,4HXPD@91061|Bacilli 91061|Bacilli G UDPglucose--hexose-1-phosphate uridylyltransferase XK27_05445 - - - - - - - - - - - - BJHFPPGC_00379 904306.HMPREF9192_1557 8.95e-222 611.0 COG1234@1|root,COG1234@2|Bacteria,1TRGP@1239|Firmicutes,4HABM@91061|Bacilli 91061|Bacilli S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA rnz GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B,Lactamase_B_2 BJHFPPGC_00380 904306.HMPREF9192_1558 5e-176 491.0 COG0300@1|root,COG0300@2|Bacteria,1TSJ3@1239|Firmicutes,4HDU5@91061|Bacilli 91061|Bacilli S Belongs to the short-chain dehydrogenases reductases (SDR) family yqjQ - - ko:K07124 - - - - ko00000 - - - adh_short BJHFPPGC_00381 1046629.Ssal_01301 4.18e-50 164.0 COG0500@1|root,COG0500@2|Bacteria,1V1BN@1239|Firmicutes,4HPJN@91061|Bacilli 91061|Bacilli Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_11,Methyltransf_23 BJHFPPGC_00382 888833.HMPREF9421_1624 2.01e-84 249.0 COG0454@1|root,COG0456@2|Bacteria 2|Bacteria K acetyltransferase GnaT - 2.5.1.16 ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 M00034,M00133 R01920,R02869,R08359 RC00021,RC00053 ko00000,ko00001,ko00002,ko01000 - - - Acetyltransf_1,Acetyltransf_10 BJHFPPGC_00383 1046629.Ssal_01299 0.0 1401.0 COG0608@1|root,COG4199@1|root,COG0608@2|Bacteria,COG4199@2|Bacteria,1TPXE@1239|Firmicutes,4H9UP@91061|Bacilli 91061|Bacilli L Single-stranded-DNA-specific exonuclease recj recJ - - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1,ssDNA-exonuc_C BJHFPPGC_00384 904306.HMPREF9192_1561 6.18e-120 342.0 COG0503@1|root,COG0503@2|Bacteria,1V1BV@1239|Firmicutes,4HFUA@91061|Bacilli 91061|Bacilli F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis apt GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 - R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 - - - Pribosyltran BJHFPPGC_00385 1046629.Ssal_01297 1.63e-231 636.0 COG1897@1|root,COG1897@2|Bacteria,1TQVR@1239|Firmicutes,4H9W4@91061|Bacilli 91061|Bacilli E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine metA GO:0003674,GO:0003824,GO:0008374,GO:0008899,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016750 2.3.1.46 ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 M00017 R01777 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - HTS BJHFPPGC_00386 1046629.Ssal_01296 1.82e-162 455.0 COG3935@1|root,COG3935@2|Bacteria 2|Bacteria - - dnaD - - ko:K02086 - - - - ko00000 - - - DnaB_2 BJHFPPGC_00387 1046629.Ssal_01295 5.28e-153 429.0 COG0177@1|root,COG0177@2|Bacteria,1TRAK@1239|Firmicutes,4HATD@91061|Bacilli 91061|Bacilli L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate nth - 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD BJHFPPGC_00389 1046629.Ssal_01292 6.97e-294 804.0 COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,4HAN2@91061|Bacilli 91061|Bacilli L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA - 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 BJHFPPGC_00390 435842.HMPREF0848_00499 2.44e-40 133.0 COG1722@1|root,COG1722@2|Bacteria,1VK9I@1239|Firmicutes 1239|Firmicutes L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseB - 3.1.11.6 ko:K03602 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_S BJHFPPGC_00391 1046629.Ssal_01290 7.15e-198 549.0 COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,4HA8E@91061|Bacilli 91061|Bacilli H Belongs to the FPP GGPP synthase family ispA GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0071704,GO:1901576 2.5.1.1,2.5.1.10,2.5.1.29 ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt BJHFPPGC_00392 1046629.Ssal_01289 4.46e-189 526.0 COG1189@1|root,COG1189@2|Bacteria,1TPE4@1239|Firmicutes,4HAPY@91061|Bacilli 91061|Bacilli J Ribosomal RNA large subunit methyltransferase J rrmJ - 2.1.1.226,2.1.1.227 ko:K06442 - - - - ko00000,ko01000,ko03009 - - - FtsJ,S4 BJHFPPGC_00393 1046629.Ssal_01288 5.12e-96 280.0 COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,4HFY8@91061|Bacilli 91061|Bacilli K Regulates arginine biosynthesis genes argR2 - - ko:K03402 - - - - ko00000,ko03000 - - - Arg_repressor,Arg_repressor_C BJHFPPGC_00394 1046629.Ssal_01287 0.0 1046.0 COG0497@1|root,COG0497@2|Bacteria,1TP99@1239|Firmicutes,4H9ZR@91061|Bacilli 91061|Bacilli L May be involved in recombinational repair of damaged DNA recN GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03631 - - - - ko00000,ko03400 - - - AAA_23,SMC_N BJHFPPGC_00395 1046629.Ssal_01286 7.99e-190 528.0 COG1307@1|root,COG1307@2|Bacteria,1TRZ4@1239|Firmicutes,4HBR8@91061|Bacilli 91061|Bacilli S DegV family WQ51_01275 - - - - - - - - - - - DegV BJHFPPGC_00396 1046629.Ssal_01285 2.51e-203 563.0 COG2755@1|root,COG2755@2|Bacteria,1V1HR@1239|Firmicutes,4HDXS@91061|Bacilli 91061|Bacilli E COG2755 Lysophospholipase L1 and related esterases XK27_03630 - - - - - - - - - - - Lipase_GDSL_2 BJHFPPGC_00397 1046629.Ssal_01284 9.19e-124 353.0 COG4698@1|root,COG4698@2|Bacteria,1VF0K@1239|Firmicutes,4HIYN@91061|Bacilli 91061|Bacilli S Protein conserved in bacteria ypmS - - - - - - - - - - - DUF2140 BJHFPPGC_00398 1046629.Ssal_01283 3.1e-52 165.0 COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,4HKF2@91061|Bacilli 91061|Bacilli L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions hup - - ko:K03530 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding BJHFPPGC_00400 1046629.Ssal_01281 2.05e-228 628.0 COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,4HBFE@91061|Bacilli 91061|Bacilli F Catalyzes the conversion of dihydroorotate to orotate pyrD GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.5.2,1.3.98.1 ko:K00226,ko:K00254 ko00240,ko01100,map00240,map01100 M00051 R01867,R01868 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh BJHFPPGC_00401 997830.HMPREF1124_2001 2.15e-169 472.0 COG0588@1|root,COG0588@2|Bacteria,1TQFP@1239|Firmicutes,4HAW7@91061|Bacilli,43G3N@68892|Streptococcus infantis 91061|Bacilli G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmA GO:0001871,GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009986,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031,GO:2001065 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 BJHFPPGC_00402 999425.HMPREF9186_01824 1.97e-70 212.0 COG1733@1|root,COG1733@2|Bacteria,1VA9M@1239|Firmicutes,4HNIX@91061|Bacilli 91061|Bacilli K HxlR-like helix-turn-helix hxlR - - - - - - - - - - - HxlR BJHFPPGC_00403 1046629.Ssal_01278 6.59e-92 268.0 COG3631@1|root,COG3631@2|Bacteria,1V9T9@1239|Firmicutes,4HWFN@91061|Bacilli 91061|Bacilli S SnoaL-like polyketide cyclase - - - ko:K06893 - - - - ko00000 - - - SnoaL_2 BJHFPPGC_00404 1000588.HMPREF9965_1767 3.58e-20 85.5 COG0588@1|root,COG0588@2|Bacteria,1TQFP@1239|Firmicutes,4HAW7@91061|Bacilli,2TP26@28037|Streptococcus mitis 91061|Bacilli G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmA GO:0001871,GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009986,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031,GO:2001065 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 BJHFPPGC_00405 1046629.Ssal_01276 0.0 1001.0 COG0119@1|root,COG0119@2|Bacteria,1TP4Y@1239|Firmicutes,4HA6E@91061|Bacilli 91061|Bacilli E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) leuA - 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS10690,iYO844.BSU28280 HMGL-like,LeuA_dimer BJHFPPGC_00406 1046629.Ssal_01275 7.84e-241 662.0 COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,4HATP@91061|Bacilli 91061|Bacilli CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate leuB GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU28270 Iso_dh BJHFPPGC_00407 1046629.Ssal_01273 0.0 947.0 COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,4HAWA@91061|Bacilli 91061|Bacilli E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuC - 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS10700 Aconitase BJHFPPGC_00408 1046629.Ssal_01272 6.51e-145 407.0 COG0066@1|root,COG0066@2|Bacteria,1V1I6@1239|Firmicutes,4HFTY@91061|Bacilli 91061|Bacilli E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuD - 4.2.1.33,4.2.1.35 ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R10170 RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase_C BJHFPPGC_00409 1046629.Ssal_01271 0.0 2005.0 COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,4H9T3@91061|Bacilli 91061|Bacilli L DNA polymerase dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon BJHFPPGC_00410 1046629.Ssal_01270 3.31e-239 658.0 COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,4HAPN@91061|Bacilli 91061|Bacilli F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis pfkA GO:0003674,GO:0003824,GO:0003872,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008443,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019200,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046835,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061615,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.11 ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 M00001,M00345 R00756,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 - - iYO844.BSU29190 PFK BJHFPPGC_00411 1046629.Ssal_01268 0.0 956.0 COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,4H9VY@91061|Bacilli 91061|Bacilli G Belongs to the pyruvate kinase family pyk GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PEP-utilizers,PK,PK_C BJHFPPGC_00412 999425.HMPREF9186_00339 0.0 4304.0 COG2373@1|root,COG4886@1|root,COG2373@2|Bacteria,COG4886@2|Bacteria,1TV1Y@1239|Firmicutes,4HBHJ@91061|Bacilli 91061|Bacilli Q the current gene model (or a revised gene model) may contain a frame shift crpB - - - - - - - - - - - Gram_pos_anchor,YSIRK_signal BJHFPPGC_00414 1046629.Ssal_01265 1.96e-228 630.0 COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,4HE7G@91061|Bacilli 91061|Bacilli S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind BJHFPPGC_00415 1046629.Ssal_01264 1.37e-190 531.0 COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,4HBMY@91061|Bacilli 91061|Bacilli S Belongs to the binding-protein-dependent transport system permease family XK27_08840 - - ko:K05832 - M00247 - - ko00000,ko00002,ko02000 - - - BPD_transp_2 BJHFPPGC_00416 1046629.Ssal_01263 3.8e-174 486.0 COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,4HCHC@91061|Bacilli 91061|Bacilli S abc transporter atp-binding protein XK27_08845 - - ko:K05833 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_tran BJHFPPGC_00417 1046629.Ssal_01262 0.0 1064.0 COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4HAAP@91061|Bacilli 91061|Bacilli S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay rnjB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 - ko:K12574 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - Lactamase_B,RMMBL BJHFPPGC_00418 1046629.Ssal_01260 4.87e-190 527.0 COG0627@1|root,COG0627@2|Bacteria,1TPA9@1239|Firmicutes,4HD64@91061|Bacilli 91061|Bacilli S Esterase estA - - ko:K03930 - - - - ko00000,ko01000 - CE1 - Esterase BJHFPPGC_00419 1046629.Ssal_01259 4.25e-160 449.0 COG5549@1|root,COG5549@2|Bacteria,1VW9X@1239|Firmicutes,4HWF8@91061|Bacilli 91061|Bacilli O Zinc-dependent metalloprotease XK27_08875 - - - - - - - - - - - Peptidase_M10 BJHFPPGC_00420 996306.SSUR61_0275 1.02e-25 100.0 29R1H@1|root,30C2M@2|Bacteria,1U92D@1239|Firmicutes,4IJ2X@91061|Bacilli,1WTJN@1307|Streptococcus suis 91061|Bacilli - - XK27_08880 - - - - - - - - - - - - BJHFPPGC_00421 435842.HMPREF0848_00535 3.48e-98 285.0 COG0716@1|root,COG0716@2|Bacteria,1V7AG@1239|Firmicutes,4HMJF@91061|Bacilli 91061|Bacilli C Flavodoxin ykuP - - ko:K03839 - - - - ko00000 - - - Flavodoxin_1 BJHFPPGC_00422 1046629.Ssal_01255 0.0 952.0 COG0038@1|root,COG0038@2|Bacteria,1TPX0@1239|Firmicutes,4HD2H@91061|Bacilli 91061|Bacilli P Chloride transporter, ClC family eriC - - ko:K03281 - - - - ko00000 2.A.49 - - TrkA_C,Voltage_CLC BJHFPPGC_00423 264199.stu1181 5.89e-53 167.0 COG1605@1|root,COG1605@2|Bacteria 2|Bacteria E Chorismate mutase pheA GO:0003674,GO:0003824,GO:0004106,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 1.3.1.12,2.3.1.79,4.2.1.51,5.4.99.5 ko:K00661,ko:K04092,ko:K04093,ko:K04516,ko:K14170,ko:K14187 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00024,M00025 R00691,R01373,R01715,R01728 RC00125,RC00360,RC03116 ko00000,ko00001,ko00002,ko01000 - - iECNA114_1301.ECNA114_2667 ACT,CM_2,PDT BJHFPPGC_00424 1046629.Ssal_01253 2.15e-265 730.0 COG0038@1|root,COG0038@2|Bacteria,1TPX0@1239|Firmicutes 1239|Firmicutes P Chloride transporter ClC family eriC - - ko:K03281 - - - - ko00000 2.A.49 - - Voltage_CLC BJHFPPGC_00425 1046629.Ssal_01252 2.33e-74 223.0 COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,4HIK3@91061|Bacilli 91061|Bacilli J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site rplS GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02884 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L19 BJHFPPGC_00428 1046629.Ssal_01245 9.42e-28 100.0 2C91M@1|root,33E1E@2|Bacteria,1VPEZ@1239|Firmicutes,4HRR2@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF3042) WQ51_02665 - - - - - - - - - - - DUF3042 BJHFPPGC_00429 1046629.Ssal_01244 2.22e-203 564.0 COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,4HAVW@91061|Bacilli 91061|Bacilli J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT BJHFPPGC_00430 1046629.Ssal_01243 1.4e-110 318.0 COG1956@1|root,COG1956@2|Bacteria,1V6GQ@1239|Firmicutes,4HH7X@91061|Bacilli 91061|Bacilli T GAF domain-containing protein ytsP - 1.8.4.14 ko:K08968 ko00270,map00270 - R02025 RC00639 ko00000,ko00001,ko01000 - - - GAF_2 BJHFPPGC_00431 1046629.Ssal_01242 0.0 1037.0 COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,4HAUE@91061|Bacilli 91061|Bacilli L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX - 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3 BJHFPPGC_00432 1046629.Ssal_01240 6.27e-219 604.0 COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,4HB60@91061|Bacilli 91061|Bacilli HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor birA - 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB,HTH_11 BJHFPPGC_00433 435842.HMPREF0848_00547 1.21e-268 737.0 COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,4HB33@91061|Bacilli 91061|Bacilli H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme metK GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - - S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N BJHFPPGC_00434 435842.HMPREF0848_00548 3.81e-274 750.0 COG0381@1|root,COG0381@2|Bacteria,1TQZT@1239|Firmicutes,4HBI3@91061|Bacilli 91061|Bacilli G Belongs to the UDP-N-acetylglucosamine 2-epimerase family mnaA - 5.1.3.14 ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420 RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 - - iSB619.SA_RS11005 Epimerase_2 BJHFPPGC_00435 435842.HMPREF0848_00549 1.58e-169 475.0 2DSSB@1|root,33H90@2|Bacteria,1W0IB@1239|Firmicutes,4HYWM@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_00437 435842.HMPREF0848_00550 4.15e-314 855.0 COG1215@1|root,COG1215@2|Bacteria,1TRCI@1239|Firmicutes,4HAAK@91061|Bacilli 91061|Bacilli M Glycosyltransferases, probably involved in cell wall biogenesis ydaM - - - - - - - - - - - Glyco_tranf_2_3 BJHFPPGC_00438 435842.HMPREF0848_00551 3.91e-248 682.0 COG3405@1|root,COG3405@2|Bacteria,1VCBY@1239|Firmicutes,4IPTW@91061|Bacilli 91061|Bacilli G Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - - - - - - - - - - Glyco_hydro_8 BJHFPPGC_00439 1046629.Ssal_01229 3.97e-294 804.0 COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,4H9KI@91061|Bacilli 91061|Bacilli M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA - 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - - EPSP_synthase BJHFPPGC_00440 1046629.Ssal_01228 2.03e-35 120.0 2EK0E@1|root,33DQZ@2|Bacteria,1VMAH@1239|Firmicutes,4HRG1@91061|Bacilli 91061|Bacilli S DNA-directed RNA polymerase subunit beta - - - - - - - - - - - - EpuA BJHFPPGC_00441 904306.HMPREF9192_1622 1.56e-198 551.0 COG2169@1|root,COG2169@2|Bacteria,1V4X2@1239|Firmicutes,4HIF5@91061|Bacilli 91061|Bacilli F DNA RNA non-specific endonuclease endA - - ko:K15051 - - - - ko00000 - - - Endonuclea_NS_2,Endonuclease_NS BJHFPPGC_00442 1046629.Ssal_01225 5.84e-142 402.0 COG0765@1|root,COG0765@2|Bacteria,1V14N@1239|Firmicutes,4HJ9W@91061|Bacilli 91061|Bacilli P ABC transporter (permease) - - - ko:K10040 ko02010,map02010 M00228 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 BJHFPPGC_00443 904306.HMPREF9192_1624 8.31e-159 446.0 COG0765@1|root,COG0765@2|Bacteria,1TQ5K@1239|Firmicutes,4HE9C@91061|Bacilli 91061|Bacilli P ABC transporter (Permease XK27_07620 - - ko:K10040 ko02010,map02010 M00228 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 BJHFPPGC_00444 1046629.Ssal_01223 3.51e-187 521.0 COG0834@1|root,COG0834@2|Bacteria,1TT11@1239|Firmicutes,4HAHV@91061|Bacilli 91061|Bacilli ET ABC-type amino acid transport signal transduction systems, periplasmic component domain peb1A - - ko:K02030,ko:K09969,ko:K10039 ko02010,map02010 M00228,M00232,M00236 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8 - - SBP_bac_3 BJHFPPGC_00445 904306.HMPREF9192_1626 1.1e-179 500.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli 91061|Bacilli E abc transporter atp-binding protein glnQ - - ko:K10041 ko02010,map02010 M00228 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran BJHFPPGC_00446 904306.HMPREF9192_1631 4.13e-165 462.0 COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,4HA8Q@91061|Bacilli 91061|Bacilli KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain yycF GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K07668 ko02020,map02020 M00459 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C BJHFPPGC_00447 1046629.Ssal_01220 1.23e-311 850.0 COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HA52@91061|Bacilli 91061|Bacilli T Histidine kinase vicK - 2.7.13.3 ko:K07652 ko02020,map02020 M00459 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_9 BJHFPPGC_00448 1046629.Ssal_01219 1.46e-196 544.0 COG1235@1|root,COG1235@2|Bacteria,1TQ8E@1239|Firmicutes,4HAKD@91061|Bacilli 91061|Bacilli S Metal-dependent hydrolases of the beta-lactamase superfamily I vicX - 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B,Lactamase_B_2 BJHFPPGC_00449 435842.HMPREF0848_00563 4.46e-74 222.0 COG2832@1|root,COG2832@2|Bacteria,1VC3R@1239|Firmicutes,4HMWE@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF454) - - - ko:K09790 - - - - ko00000 - - - DUF454 BJHFPPGC_00450 904306.HMPREF9192_1635 3.36e-290 792.0 COG2348@1|root,COG2348@2|Bacteria,1TRZU@1239|Firmicutes,4HC1Z@91061|Bacilli 91061|Bacilli V protein involved in methicillin resistance femX - 2.3.2.10,2.3.2.16 ko:K05363,ko:K11693 ko00550,ko01100,map00550,map01100 - R08776,R08779 RC00055,RC00096 ko00000,ko00001,ko01000,ko01011 - - - FemAB BJHFPPGC_00451 435842.HMPREF0848_00565 1.89e-187 521.0 COG0561@1|root,COG0561@2|Bacteria,1TR16@1239|Firmicutes,4HCZ6@91061|Bacilli 91061|Bacilli S hydrolases of the HAD superfamily XK27_00835 - - - - - - - - - - - Hydrolase_3 BJHFPPGC_00452 435842.HMPREF0848_00566 1.95e-175 492.0 COG0454@1|root,COG0456@2|Bacteria,1VD7Z@1239|Firmicutes,4HGYD@91061|Bacilli 91061|Bacilli K Acetyltransferase GNAT family XK27_00115 - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 BJHFPPGC_00453 1046629.Ssal_01211 4.84e-89 261.0 COG4506@1|root,COG4506@2|Bacteria 2|Bacteria S Domain of unknown function (DUF1934) ywiB - - - - - - - - - - - DUF1934 BJHFPPGC_00454 1046629.Ssal_01209 0.0 1615.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9S5@91061|Bacilli 91061|Bacilli P cation transport ATPase pacL - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase BJHFPPGC_00455 1046629.Ssal_01208 8.6e-169 472.0 COG0778@1|root,COG0778@2|Bacteria,1UB8S@1239|Firmicutes,4HEGP@91061|Bacilli 91061|Bacilli C nitroreductase nfrA - 1.5.1.38 ko:K19285 ko00740,ko01100,map00740,map01100 - R05706 RC00126 ko00000,ko00001,ko01000 - - - Nitroreductase BJHFPPGC_00456 1046629.Ssal_01207 5.19e-196 544.0 COG1409@1|root,COG1409@2|Bacteria,1V9B5@1239|Firmicutes,4HJX0@91061|Bacilli 91061|Bacilli S Calcineurin-like phosphoesterase - - - - - - - - - - - - Metallophos BJHFPPGC_00457 1046629.Ssal_01206 4.55e-265 726.0 COG1600@1|root,COG1600@2|Bacteria,1TP6Q@1239|Firmicutes,4HAEW@91061|Bacilli 91061|Bacilli C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) queG GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 ko:K18979 - - - - ko00000,ko01000,ko03016 - - - DUF1730,Fer4_16,HEAT_2 BJHFPPGC_00458 1046629.Ssal_01205 1.08e-231 638.0 COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,4H9N2@91061|Bacilli 91061|Bacilli J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA prfB - - ko:K02836 - - - - ko00000,ko03012 - - - PCRF,RF-1 BJHFPPGC_00459 264199.stu1145 7.31e-160 448.0 COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,4H9Z2@91061|Bacilli 91061|Bacilli D cell division ATP-binding protein FtsE ftsE - - ko:K09812 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - ABC_tran BJHFPPGC_00460 904306.HMPREF9192_1646 8.45e-211 583.0 COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,4HA5A@91061|Bacilli 91061|Bacilli D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation ftsX - - ko:K09811 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - FtsX BJHFPPGC_00461 1046629.Ssal_01202 6.84e-118 336.0 COG1051@1|root,COG1051@2|Bacteria,1V66I@1239|Firmicutes,4HHRE@91061|Bacilli 91061|Bacilli F NTP pyrophosphohydrolases including oxidative damage repair enzymes mutX - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX BJHFPPGC_00462 1046629.Ssal_01201 3e-232 645.0 COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,4H9SR@91061|Bacilli 91061|Bacilli S permease XK27_05220 - - - - - - - - - - - AI-2E_transport BJHFPPGC_00463 1046629.Ssal_01200 1.7e-281 771.0 COG0457@1|root,COG0457@2|Bacteria,1TT97@1239|Firmicutes,4HAIA@91061|Bacilli 91061|Bacilli G COG0457 FOG TPR repeat XK27_05225 - - - - - - - - - - - TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8 BJHFPPGC_00464 1046629.Ssal_01199 1.8e-123 352.0 COG0681@1|root,COG0681@2|Bacteria,1V2BJ@1239|Firmicutes,4HGCB@91061|Bacilli 91061|Bacilli U Belongs to the peptidase S26 family sipC - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 BJHFPPGC_00465 1046629.Ssal_01197 0.0 1305.0 COG0860@1|root,COG1705@1|root,COG0860@2|Bacteria,COG1705@2|Bacteria,1TR6H@1239|Firmicutes,4H9U6@91061|Bacilli 91061|Bacilli M N-acetylmuramoyl-L-alanine amidase lytC_1 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3,SH3_3,SLH BJHFPPGC_00466 1046629.Ssal_01196 3.8e-293 800.0 COG2195@1|root,COG2195@2|Bacteria,1TP3A@1239|Firmicutes,4HAZE@91061|Bacilli 91061|Bacilli E Cleaves the N-terminal amino acid of tripeptides pepT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:1901564 3.4.11.4 ko:K01258 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20,Peptidase_M42 BJHFPPGC_00467 904306.HMPREF9192_1653 2.86e-113 325.0 2FI04@1|root,349T2@2|Bacteria,1VQ5S@1239|Firmicutes,4HYC5@91061|Bacilli 91061|Bacilli S Family of unknown function (DUF5322) ebsA - - - - - - - - - - - DUF5322 BJHFPPGC_00468 1046629.Ssal_01194 3.71e-29 115.0 COG1388@1|root,COG1388@2|Bacteria,1VFEU@1239|Firmicutes,4HNW5@91061|Bacilli 91061|Bacilli M LysM domain - - - - - - - - - - - - LysM BJHFPPGC_00469 1046629.Ssal_01193 2.39e-155 436.0 COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,4HFZE@91061|Bacilli 91061|Bacilli F Belongs to the cytidylate kinase family. Type 1 subfamily cmk GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 ko:K00945 ko00240,ko01100,map00240,map01100 M00052 R00158,R00512,R01665 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Cytidylate_kin BJHFPPGC_00470 1046629.Ssal_01192 1.1e-115 332.0 COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes,4HI4P@91061|Bacilli 91061|Bacilli J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins infC GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - ko:K02520 - - - - ko00000,ko03012,ko03029 - - - IF3_C,IF3_N BJHFPPGC_00471 1046629.Ssal_01191 2.36e-38 128.0 COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,4HNIQ@91061|Bacilli 91061|Bacilli J Belongs to the bacterial ribosomal protein bL35 family rpmI GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02916 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L35p BJHFPPGC_00472 1046629.Ssal_01190 1.82e-73 221.0 COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,4HH2W@91061|Bacilli 91061|Bacilli J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit rplT GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - ko:K02887 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L20 BJHFPPGC_00473 435842.HMPREF0848_00589 4.17e-24 94.7 COG0454@1|root,COG0456@2|Bacteria,1V77V@1239|Firmicutes,4HKYX@91061|Bacilli 91061|Bacilli K Gnat family XK27_03610 - - - - - - - - - - - Acetyltransf_1 BJHFPPGC_00474 1046629.Ssal_01189 4.21e-67 206.0 COG0454@1|root,COG0456@2|Bacteria,1V77V@1239|Firmicutes,4HKYX@91061|Bacilli 91061|Bacilli K Gnat family XK27_03610 - - - - - - - - - - - Acetyltransf_1 BJHFPPGC_00475 1046629.Ssal_01188 6.9e-113 325.0 2BWFV@1|root,32QWV@2|Bacteria,1V8UN@1239|Firmicutes,4HK47@91061|Bacilli 91061|Bacilli - - yybC - - - - - - - - - - - DUF2798 BJHFPPGC_00476 1046629.Ssal_01187 1.38e-37 125.0 COG1942@1|root,COG1942@2|Bacteria,1VKD5@1239|Firmicutes,4HRBS@91061|Bacilli 91061|Bacilli G Belongs to the 4-oxalocrotonate tautomerase family dmpI GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0044237 5.3.2.6 ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 M00569 R03966,R05389 RC01040,RC01355 ko00000,ko00001,ko00002,ko01000 - - - Tautomerase BJHFPPGC_00477 1046629.Ssal_01186 0.0 924.0 COG0624@1|root,COG0624@2|Bacteria,1TPEG@1239|Firmicutes,4HC14@91061|Bacilli 91061|Bacilli E Dipeptidase pepV - 3.5.1.18 ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 M00016 R00899,R02734,R04951 RC00064,RC00090,RC00096,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 BJHFPPGC_00478 1046629.Ssal_01185 3.35e-137 388.0 COG1573@1|root,COG1573@2|Bacteria,1V1F8@1239|Firmicutes,4HFVS@91061|Bacilli 91061|Bacilli L Uracil-DNA glycosylase ung2 - - - - - - - - - - - UDG BJHFPPGC_00479 435842.HMPREF0848_00593 3.59e-308 900.0 COG3266@1|root,COG3266@2|Bacteria,1VU2V@1239|Firmicutes,4HU5W@91061|Bacilli 91061|Bacilli V Glucan-binding protein C - - - - - - - - - - - - GbpC,Gram_pos_anchor,YSIRK_signal BJHFPPGC_00480 1046629.Ssal_01025 0.0 1167.0 COG3266@1|root,COG3266@2|Bacteria,1VU2V@1239|Firmicutes,4HU5W@91061|Bacilli 91061|Bacilli V Glucan-binding protein C - - - ko:K13732 ko05100,map05100 - - - ko00000,ko00001 - - - GbpC,Gram_pos_anchor,YSIRK_signal BJHFPPGC_00481 1046629.Ssal_01026 4.82e-155 436.0 COG0120@1|root,COG0120@2|Bacteria,1V1DB@1239|Firmicutes,4HFQ7@91061|Bacilli 91061|Bacilli G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate rpiA - 5.3.1.6 ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056 RC00434 ko00000,ko00001,ko00002,ko01000 - - - Rib_5-P_isom_A BJHFPPGC_00482 435842.HMPREF0848_00596 2.49e-296 808.0 COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,4H9RU@91061|Bacilli 91061|Bacilli G Phosphotransfer between the C1 and C5 carbon atoms of pentose deoB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008973,GO:0016853,GO:0016866,GO:0016868,GO:0044424,GO:0044444,GO:0044464 5.4.2.7 ko:K01839 ko00030,ko00230,map00030,map00230 - R01057,R02749 RC00408 ko00000,ko00001,ko01000 - - - Metalloenzyme BJHFPPGC_00483 1046629.Ssal_01028 6e-111 320.0 COG3797@1|root,COG3797@2|Bacteria,1V426@1239|Firmicutes,4HI2S@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF1697) - - - - - - - - - - - - DUF1697 BJHFPPGC_00484 1046629.Ssal_01029 8.38e-191 530.0 COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli 91061|Bacilli F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate punA - 2.4.2.1,2.4.2.28 ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 M00034 R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 RC00033,RC00063,RC00122,RC02819 ko00000,ko00001,ko00002,ko01000 - - - PNP_UDP_1 BJHFPPGC_00485 1123314.AUIO01000012_gene1814 2.56e-63 204.0 COG1704@1|root,COG1704@2|Bacteria 2|Bacteria S LemA family - - - ko:K03744 - - - - ko00000 - - - GIDE,LemA BJHFPPGC_00486 435842.HMPREF0848_00599 1.14e-201 569.0 COG0038@1|root,COG0038@2|Bacteria,1V07H@1239|Firmicutes 1239|Firmicutes P chloride clcA2 - - - - - - - - - - - Voltage_CLC BJHFPPGC_00487 1046629.Ssal_01031 2.91e-166 465.0 COG0518@1|root,COG0518@2|Bacteria,1V97T@1239|Firmicutes,4HIKV@91061|Bacilli 91061|Bacilli F glutamine amidotransferase gat - 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase BJHFPPGC_00488 435842.HMPREF0848_00601 1.49e-163 458.0 COG0813@1|root,COG0813@2|Bacteria,1TQPG@1239|Firmicutes,4HADM@91061|Bacilli 91061|Bacilli F purine nucleoside phosphorylase deoD - 2.4.2.1 ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 RC00033,RC00063,RC00122 ko00000,ko00001,ko01000 - - - PNP_UDP_1 BJHFPPGC_00489 322159.STER_1071 0.0 870.0 COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,4HDRS@91061|Bacilli 91061|Bacilli K Cell envelope-like function transcriptional attenuator common domain protein cps4A - - - - - - - - - - - DNA_PPF,LytR_cpsA_psr BJHFPPGC_00490 322159.STER_1070 7.12e-170 474.0 COG4464@1|root,COG4464@2|Bacteria,1TQ1T@1239|Firmicutes,4HDZR@91061|Bacilli 91061|Bacilli GM Capsular polysaccharide biosynthesis protein cpsB - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - - BJHFPPGC_00491 435842.HMPREF0848_00604 1.19e-141 402.0 COG3944@1|root,COG3944@2|Bacteria,1UZCR@1239|Firmicutes,4HE26@91061|Bacilli 91061|Bacilli M biosynthesis protein capA - - - - - - - - - - - GNVR,Wzz BJHFPPGC_00492 322159.STER_1068 4.12e-150 425.0 COG0489@1|root,COG0489@2|Bacteria,1TS4R@1239|Firmicutes,4HCEN@91061|Bacilli 91061|Bacilli D COG0489 ATPases involved in chromosome partitioning cpsD - - - - - - - - - - - AAA_31 BJHFPPGC_00493 264199.stu1108 0.0 868.0 COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,4HB3Z@91061|Bacilli 91061|Bacilli M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase cpsE - - - - - - - - - - - Bac_transf,CoA_binding_3 BJHFPPGC_00494 904306.HMPREF9192_1679 3.17e-281 768.0 COG0438@1|root,COG0438@2|Bacteria,1TR0Y@1239|Firmicutes,4IPU2@91061|Bacilli 91061|Bacilli M group 1 family protein rgpAc - - ko:K12996 - - - - ko00000,ko01000,ko01003,ko01005 - GT4 - DUF1972,Glycos_transf_1 BJHFPPGC_00495 1116231.SMA_0863 2.35e-265 728.0 COG0438@1|root,COG0438@2|Bacteria,1TR6R@1239|Firmicutes,4HEIZ@91061|Bacilli 91061|Bacilli M Glycosyltransferase, group 1 family protein - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 BJHFPPGC_00496 904306.HMPREF9192_1681 4.52e-132 375.0 COG3955@1|root,COG3955@2|Bacteria,1V8R9@1239|Firmicutes,4HW77@91061|Bacilli 91061|Bacilli M Domain of unknown function (DUF1919) - - - - - - - - - - - - DUF1919 BJHFPPGC_00497 862970.SAIN_1722 1.39e-212 589.0 COG1215@1|root,COG1215@2|Bacteria,1V0TF@1239|Firmicutes,4ISVG@91061|Bacilli 91061|Bacilli M Glycosyltransferase, group 2 family protein - - - - - - - - - - - - Glyco_trans_1_2,Glycos_transf_2 BJHFPPGC_00498 246201.SM12261_1001 7.31e-162 461.0 COG0438@1|root,COG0438@2|Bacteria,1TPG9@1239|Firmicutes,4HGEP@91061|Bacilli 91061|Bacilli M Stealth protein CR2, conserved region 2 wefC - - - - - - - - - - - Stealth_CR1,Stealth_CR2,Stealth_CR3,Stealth_CR4 BJHFPPGC_00499 1116231.SMA_0867 4.03e-219 610.0 COG0438@1|root,COG0438@2|Bacteria,1TRCM@1239|Firmicutes,4HC0S@91061|Bacilli 91061|Bacilli M Glycosyltransferase - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 BJHFPPGC_00500 1116231.SMA_0868 1.04e-220 608.0 COG1216@1|root,COG1216@2|Bacteria,1UYRR@1239|Firmicutes,4HEJ1@91061|Bacilli 91061|Bacilli S glycosyl transferase family 2 galnac-T15 - - ko:K07011 - - - - ko00000 - - - Glyco_tranf_2_3,Glyco_trans_2_3,Glyco_transf_7C,Glycos_transf_2 BJHFPPGC_00501 1116231.SMA_0869 3.69e-278 763.0 2ATWB@1|root,31JFJ@2|Bacteria,1U49M@1239|Firmicutes,4HZJD@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_00502 1116231.SMA_0870 2.07e-304 835.0 COG2244@1|root,COG2244@2|Bacteria,1TP7R@1239|Firmicutes,4HEKI@91061|Bacilli 91061|Bacilli S Polysaccharide biosynthesis protein - - - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt,Polysacc_synt_C BJHFPPGC_00503 1316408.HSISM1_85 3.33e-265 726.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 BJHFPPGC_00504 1046629.Ssal_01165 3.2e-176 493.0 COG0561@1|root,COG0561@2|Bacteria,1V1SQ@1239|Firmicutes,4IPTG@91061|Bacilli 91061|Bacilli S Sucrose-6F-phosphate phosphohydrolase supH - - - - - - - - - - - Hydrolase_3 BJHFPPGC_00505 904306.HMPREF9192_1692 6.72e-140 395.0 COG0406@1|root,COG0406@2|Bacteria,1UXY8@1239|Firmicutes,4HFD9@91061|Bacilli 91061|Bacilli G Belongs to the phosphoglycerate mutase family XK27_06100 - - - - - - - - - - - His_Phos_1 BJHFPPGC_00506 435842.HMPREF0848_00618 1.58e-139 394.0 COG0406@1|root,COG0406@2|Bacteria,1UXY8@1239|Firmicutes,4HFD9@91061|Bacilli 91061|Bacilli G Belongs to the phosphoglycerate mutase family - - - - - - - - - - - - His_Phos_1 BJHFPPGC_00507 904306.HMPREF9192_1694 2.35e-139 394.0 COG0406@1|root,COG0406@2|Bacteria,1UXY8@1239|Firmicutes,4HFD9@91061|Bacilli 91061|Bacilli G Belongs to the phosphoglycerate mutase family - - - - - - - - - - - - His_Phos_1 BJHFPPGC_00508 1046629.Ssal_01161 1.03e-248 685.0 COG0628@1|root,COG0628@2|Bacteria,1TQBF@1239|Firmicutes,4HGFS@91061|Bacilli 91061|Bacilli S hmm pf01594 XK27_12525 - - - - - - - - - - - AI-2E_transport BJHFPPGC_00509 1046629.Ssal_01160 0.0 968.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family bglA - 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 BJHFPPGC_00510 1046629.Ssal_01159 3.9e-51 162.0 COG3937@1|root,COG3937@2|Bacteria,1VK6K@1239|Firmicutes,4HRS5@91061|Bacilli 91061|Bacilli S granule-associated protein - - - - - - - - - - - - - BJHFPPGC_00511 1046629.Ssal_01158 0.0 964.0 COG0661@1|root,COG0661@2|Bacteria,1TPIV@1239|Firmicutes,4HBW3@91061|Bacilli 91061|Bacilli S unusual protein kinase ubiB - - ko:K03688 - - - - ko00000 - - - ABC1,APH BJHFPPGC_00512 904306.HMPREF9192_1701 2.78e-128 366.0 COG2755@1|root,COG2755@2|Bacteria,1VHUN@1239|Firmicutes,4IPN1@91061|Bacilli 91061|Bacilli E Lysophospholipase L1 and related esterases - - - - - - - - - - - - Lipase_GDSL,Lipase_GDSL_2 BJHFPPGC_00513 1046629.Ssal_01156 6.34e-193 536.0 COG4667@1|root,COG4667@2|Bacteria,1TQ9W@1239|Firmicutes,4HCHJ@91061|Bacilli 91061|Bacilli S Phospholipase, patatin family - - - - - - - - - - - - Patatin BJHFPPGC_00514 1046629.Ssal_01155 1.84e-314 857.0 COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,4HD0P@91061|Bacilli 91061|Bacilli M Belongs to the peptidase S11 family dacA1 - 3.4.16.4 ko:K01286 - - - - ko00000,ko01000 - - - DUF1958,Peptidase_S11 BJHFPPGC_00515 1046629.Ssal_01154 1.6e-269 739.0 COG0053@1|root,COG4994@1|root,COG0053@2|Bacteria,COG4994@2|Bacteria,1TSGY@1239|Firmicutes,4H9WP@91061|Bacilli 91061|Bacilli P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family yeaB - - - - - - - - - - - Cation_efflux,ZT_dimer BJHFPPGC_00516 904306.HMPREF9192_1707 4.01e-154 432.0 COG0692@1|root,COG0692@2|Bacteria,1TPSN@1239|Firmicutes,4HBTR@91061|Bacilli 91061|Bacilli L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine ung GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG BJHFPPGC_00517 1046629.Ssal_01152 2.42e-299 817.0 COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,4HA90@91061|Bacilli 91061|Bacilli F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily pyrC GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 BJHFPPGC_00518 1046629.Ssal_01151 0.0 1144.0 COG4907@1|root,COG4907@2|Bacteria,1TS3Q@1239|Firmicutes,4HF7D@91061|Bacilli 91061|Bacilli S the current gene model (or a revised gene model) may contain a frame shift - - - - - - - - - - - - DUF2207 BJHFPPGC_00519 1046629.Ssal_01148 0.0 1826.0 COG1203@1|root,COG1203@2|Bacteria,1TQ9B@1239|Firmicutes,4HAH7@91061|Bacilli 91061|Bacilli L CRISPR-associated helicase cas3 cas3 - - ko:K07012 - - - - ko00000,ko01000,ko02048 - - - DEAD,Helicase_C BJHFPPGC_00520 1046629.Ssal_01147 0.0 1100.0 COG1203@1|root,COG1203@2|Bacteria,1TSVP@1239|Firmicutes 1239|Firmicutes L An automated process has identified a potential problem with this gene model casA - - ko:K19123 - - - - ko00000,ko02048 - - - CRISPR_Cse1 BJHFPPGC_00521 1046629.Ssal_01146 6.99e-136 385.0 2CK1Q@1|root,32UPV@2|Bacteria,1VB3D@1239|Firmicutes 1239|Firmicutes S CRISPR system CASCADE complex protein CasB casB - - ko:K19046 - - - - ko00000,ko02048 - - - CRISPR_Cse2 BJHFPPGC_00522 435842.HMPREF0848_00633 1.23e-233 645.0 COG1857@1|root,COG1857@2|Bacteria,1TSM0@1239|Firmicutes,4HTJZ@91061|Bacilli 91061|Bacilli L CT1975-like protein casC - - ko:K19124 - - - - ko00000,ko02048 - - - Cas_CT1975 BJHFPPGC_00523 1046629.Ssal_01144 1.67e-170 476.0 2DBXF@1|root,2ZBPB@2|Bacteria,1V2K8@1239|Firmicutes 1239|Firmicutes S CRISPR system CASCADE complex protein CasD casD - - ko:K19125 - - - - ko00000,ko02048 - - - Cas_Cas5d BJHFPPGC_00524 435842.HMPREF0848_00635 6.11e-142 401.0 2DKU6@1|root,30BEK@2|Bacteria,1V5I4@1239|Firmicutes 1239|Firmicutes S CRISPR system CASCADE complex protein CasE casE - - ko:K19126 - - - - ko00000,ko02048 - - - CRISPR_assoc BJHFPPGC_00525 435842.HMPREF0848_00636 3.08e-215 595.0 COG1518@1|root,COG1518@2|Bacteria,1TQ6F@1239|Firmicutes 1239|Firmicutes L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette cas1 - - ko:K15342 - - - - ko00000,ko02048,ko03400 - - - Cas_Cas1 BJHFPPGC_00526 1046629.Ssal_01141 2.52e-208 577.0 COG0847@1|root,COG0847@2|Bacteria,1V0CE@1239|Firmicutes 1239|Firmicutes L CRISPR-associated endoribonuclease Cas2 cas2 - - ko:K09951 - - - - ko00000,ko02048 - - - Cas_Cas2CT1978,RNase_T BJHFPPGC_00527 1046629.Ssal_01140 1.31e-286 785.0 COG3290@1|root,COG3290@2|Bacteria 2|Bacteria T protein histidine kinase activity - - 2.7.13.3 ko:K07706 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - GGDEF,HATPase_c,HATPase_c_5,HD,HD_5,HisKA_3,MASE3,PAS,PAS_3,PAS_4,PAS_9,dCache_3 BJHFPPGC_00528 1046629.Ssal_01139 1.12e-258 713.0 COG3290@1|root,COG3290@2|Bacteria 2|Bacteria T protein histidine kinase activity hpk9 - 2.7.13.3 ko:K07706 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c_5,PAS_9 BJHFPPGC_00529 1046629.Ssal_01138 2.06e-234 644.0 COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,4HBEA@91061|Bacilli 91061|Bacilli C Dehydrogenase E1 component acoA - 1.2.4.1 ko:K00161,ko:K21416 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh BJHFPPGC_00530 1046629.Ssal_01137 1.33e-230 635.0 COG0022@1|root,COG0022@2|Bacteria,1TP3J@1239|Firmicutes,4HAP6@91061|Bacilli 91061|Bacilli C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit acoB - 1.2.4.1 ko:K00162,ko:K21417 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C BJHFPPGC_00531 904306.HMPREF9192_1713 4.98e-274 756.0 COG0508@1|root,COG0508@2|Bacteria,1TR5N@1239|Firmicutes,4HDFT@91061|Bacilli 91061|Bacilli C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex acoC - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding BJHFPPGC_00532 1046629.Ssal_01135 0.0 1085.0 COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4H9Z5@91061|Bacilli 91061|Bacilli C Dehydrogenase lpdA - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim BJHFPPGC_00533 904306.HMPREF9192_1715 0.0 2019.0 COG0860@1|root,COG1705@1|root,COG3757@1|root,COG5263@1|root,COG0860@2|Bacteria,COG1705@2|Bacteria,COG3757@2|Bacteria,COG5263@2|Bacteria 2|Bacteria S dextransucrase activity - - 3.5.1.28 ko:K01448,ko:K02395,ko:K21471 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko02035,ko03036 - - - Amidase_3,CW_binding_1,GBS_Bsp-like,Glucosaminidase,Glyco_hydro_25,Peptidase_C39_2 BJHFPPGC_00534 435842.HMPREF0848_00646 0.0 1574.0 COG0860@1|root,COG1705@1|root,COG0860@2|Bacteria,COG1705@2|Bacteria,1V5SF@1239|Firmicutes 1239|Firmicutes M N-Acetylmuramoyl-L-alanine amidase amiA - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - AMIN,Amidase_3,Cu_amine_oxidN1 BJHFPPGC_00535 1046629.Ssal_01131 0.0 2355.0 COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,4HBP5@91061|Bacilli 91061|Bacilli G belongs to the glycosyl hydrolase 13 family pulA2 - 3.2.1.1,3.2.1.41 ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 - R02108,R02111,R02112,R11262 - ko00000,ko00001,ko01000 - CBM48,GH13 - Alpha-amylase,Big_2,CBM_48,G5,Gram_pos_anchor,PUD,SLH,YSIRK_signal BJHFPPGC_00536 1046629.Ssal_01125 3.25e-194 540.0 COG2822@1|root,COG2822@2|Bacteria,1TS89@1239|Firmicutes,4HB0W@91061|Bacilli 91061|Bacilli P periplasmic lipoprotein involved in iron transport ycdO GO:0000041,GO:0006810,GO:0006811,GO:0006812,GO:0006826,GO:0008150,GO:0015684,GO:0030001,GO:0051179,GO:0051234,GO:0070838,GO:0072511 - ko:K07224 - - - - ko00000,ko02000 2.A.108.2.3 - - Peptidase_M75 BJHFPPGC_00537 904306.HMPREF9192_1720 1.67e-293 800.0 COG2837@1|root,COG2837@2|Bacteria,1UY9Y@1239|Firmicutes,4HACQ@91061|Bacilli 91061|Bacilli P peroxidase ywbN GO:0005575,GO:0005576 - ko:K07223,ko:K16301 - - - - ko00000,ko01000,ko02000 2.A.108.2.3 - iYO844.BSU38260 Dyp_perox,TAT_signal BJHFPPGC_00538 904306.HMPREF9192_1721 0.0 1004.0 COG0672@1|root,COG0672@2|Bacteria,1TQIA@1239|Firmicutes,4HCJZ@91061|Bacilli 91061|Bacilli P COG0672 High-affinity Fe2 Pb2 permease ywbL - - ko:K07243 - - - - ko00000,ko02000 2.A.108.1,2.A.108.2 - - FTR1 BJHFPPGC_00539 435842.HMPREF0848_00652 2.18e-159 448.0 COG0805@1|root,COG0805@2|Bacteria,1U7N7@1239|Firmicutes,4HB1U@91061|Bacilli 91061|Bacilli U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes tatC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - ko:K03118 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - TatC BJHFPPGC_00540 904306.HMPREF9192_1723 6.81e-34 116.0 COG1826@1|root,COG1826@2|Bacteria 2|Bacteria U protein secretion tatA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - ko:K03116,ko:K03117 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 BJHFPPGC_00541 1046629.Ssal_01120 6.5e-268 734.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4HAMQ@91061|Bacilli 91061|Bacilli P Belongs to the ABC transporter superfamily msmX - - ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1 - - ABC_tran,TOBE,TOBE_2 BJHFPPGC_00542 1046629.Ssal_01119 1.75e-192 535.0 COG3833@1|root,COG3833@2|Bacteria,1TRB7@1239|Firmicutes,4HC5K@91061|Bacilli 91061|Bacilli P ABC transporter (Permease malG - - ko:K15772 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - - BPD_transp_1 BJHFPPGC_00543 904306.HMPREF9192_1726 0.0 865.0 COG1175@1|root,COG1175@2|Bacteria,1TR2A@1239|Firmicutes,4HB8H@91061|Bacilli 91061|Bacilli P ABC transporter (Permease malF - - ko:K15771 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - - BPD_transp_1 BJHFPPGC_00544 1046629.Ssal_01117 9.67e-291 795.0 COG2182@1|root,COG2182@2|Bacteria,1TPU9@1239|Firmicutes,4H9TU@91061|Bacilli 91061|Bacilli G ABC transporter malX - - ko:K15770 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - - SBP_bac_8 BJHFPPGC_00545 1046629.Ssal_01116 1.58e-222 615.0 COG1609@1|root,COG1609@2|Bacteria,1TPZM@1239|Firmicutes,4H9ZT@91061|Bacilli 91061|Bacilli K Transcriptional regulator malR - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 BJHFPPGC_00546 1046629.Ssal_01115 0.0 1020.0 COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,4HCHB@91061|Bacilli 91061|Bacilli G 4-alpha-glucanotransferase malQ - 2.4.1.25 ko:K00705 ko00500,ko01100,map00500,map01100 - R05196 RC00049 ko00000,ko00001,ko01000 - GH77 - Glyco_hydro_77 BJHFPPGC_00547 1046629.Ssal_01114 0.0 1474.0 COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,4H9XI@91061|Bacilli 91061|Bacilli G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties glgP - 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - Phosphorylase BJHFPPGC_00549 1046629.Ssal_01112 8.44e-237 651.0 COG0095@1|root,COG0095@2|Bacteria,1TQ5U@1239|Firmicutes,4H9P6@91061|Bacilli 91061|Bacilli H Lipoate-protein ligase lplA - 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 - R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB,Lip_prot_lig_C BJHFPPGC_00550 1046629.Ssal_01108 2.53e-246 677.0 COG4974@1|root,COG4974@2|Bacteria,1URNQ@1239|Firmicutes,4HEPI@91061|Bacilli 91061|Bacilli D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division xerS - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase BJHFPPGC_00551 1046629.Ssal_01107 0.0 1656.0 COG0308@1|root,COG0308@2|Bacteria,1TR43@1239|Firmicutes,4HA20@91061|Bacilli 91061|Bacilli E aminopeptidase pepN GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - ERAP1_C,Peptidase_M1 BJHFPPGC_00552 904306.HMPREF9192_1735 3.82e-148 417.0 COG0704@1|root,COG0704@2|Bacteria,1URN3@1239|Firmicutes,4HEU9@91061|Bacilli 91061|Bacilli P Plays a role in the regulation of phosphate uptake phoU - - ko:K02039 - - - - ko00000 - - - PhoU BJHFPPGC_00553 1046629.Ssal_01105 2.49e-179 499.0 COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,4HAB1@91061|Bacilli 91061|Bacilli P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB1 - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran BJHFPPGC_00554 1046629.Ssal_01104 4.33e-192 533.0 COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,4HAB1@91061|Bacilli 91061|Bacilli P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB2 - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran BJHFPPGC_00555 904306.HMPREF9192_1738 1.02e-199 554.0 COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,4HAKF@91061|Bacilli 91061|Bacilli P phosphate transport system permease pstA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 BJHFPPGC_00556 904306.HMPREF9192_1739 6.58e-201 558.0 COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,4HC9H@91061|Bacilli 91061|Bacilli P probably responsible for the translocation of the substrate across the membrane pstC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02037 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 BJHFPPGC_00557 904306.HMPREF9192_1740 3.28e-199 553.0 COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,4HBEB@91061|Bacilli 91061|Bacilli P phosphate pstS GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015698,GO:0042301,GO:0043167,GO:0043168,GO:0051179,GO:0051234 - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 BJHFPPGC_00558 904306.HMPREF9192_1741 1.09e-309 844.0 COG0144@1|root,COG3270@1|root,COG0144@2|Bacteria,COG3270@2|Bacteria,1TPGQ@1239|Firmicutes,4HCHQ@91061|Bacilli 91061|Bacilli J NOL1 NOP2 sun family protein rsmF - - - - - - - - - - - Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA,RsmF_methylt_CI BJHFPPGC_00559 1046629.Ssal_01099 2.57e-181 504.0 COG0483@1|root,COG0483@2|Bacteria,1TR4E@1239|Firmicutes,4HB92@91061|Bacilli 91061|Bacilli G Belongs to the inositol monophosphatase superfamily suhB GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P BJHFPPGC_00560 1046629.Ssal_01098 1.4e-58 181.0 COG4476@1|root,COG4476@2|Bacteria,1VEK8@1239|Firmicutes,4HNKR@91061|Bacilli 91061|Bacilli S Belongs to the UPF0223 family yktA - - - - - - - - - - - UPF0223 BJHFPPGC_00561 1046629.Ssal_01097 4.06e-59 183.0 COG1393@1|root,COG1393@2|Bacteria,1V3QC@1239|Firmicutes 1239|Firmicutes K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress spxA - - ko:K16509 - - - - ko00000 - - - ArsC BJHFPPGC_00562 1046629.Ssal_01096 6.02e-217 598.0 COG0196@1|root,COG0196@2|Bacteria,1TPKS@1239|Firmicutes,4H9KE@91061|Bacilli 91061|Bacilli H Belongs to the ribF family ribF - 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06310 FAD_syn,Flavokinase BJHFPPGC_00563 904306.HMPREF9192_1746 5.02e-187 521.0 COG0130@1|root,COG0130@2|Bacteria,1TP9Y@1239|Firmicutes,4HA9X@91061|Bacilli 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs truB GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 ko:K03177,ko:K03483 - - - - ko00000,ko01000,ko03000,ko03016 - - iSB619.SA_RS06305 TruB-C_2,TruB_C_2,TruB_N BJHFPPGC_00564 1046629.Ssal_01094 7.65e-307 838.0 COG2461@1|root,COG2461@2|Bacteria,1TRD5@1239|Firmicutes,4HAAW@91061|Bacilli 91061|Bacilli S hemerythrin HHE cation binding domain XK27_04775 - - ko:K09155 - - - - ko00000 - - - DUF438,Hemerythrin,PAS_10 BJHFPPGC_00565 435842.HMPREF0848_00681 2.93e-46 149.0 COG2461@1|root,COG2461@2|Bacteria 2|Bacteria P Hemerythrin HHE cation binding domain protein M1-755 - - ko:K09155 - - - - ko00000 - - - DUF1858,DUF438,Hemerythrin,PAS_10 BJHFPPGC_00566 904306.HMPREF9192_1749 9.49e-143 403.0 COG0732@1|root,COG0732@2|Bacteria,1VQES@1239|Firmicutes,4HE4K@91061|Bacilli 91061|Bacilli V Type I restriction modification DNA specificity domain hsdS2 - - - - - - - - - - - Methylase_S BJHFPPGC_00567 1046629.Ssal_01091 1e-112 323.0 COG2077@1|root,COG2077@2|Bacteria,1V474@1239|Firmicutes,4HFMW@91061|Bacilli 91061|Bacilli O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides tpx - 1.11.1.15 ko:K11065 - - - - ko00000,ko01000 - - - AhpC-TSA,Redoxin BJHFPPGC_00568 904306.HMPREF9192_1752 5.84e-173 483.0 COG0561@1|root,COG0561@2|Bacteria,1TQTU@1239|Firmicutes,4HEHK@91061|Bacilli 91061|Bacilli S haloacid dehalogenase-like hydrolase - - - - - - - - - - - - Hydrolase_3 BJHFPPGC_00569 322159.STER_0995 3.44e-306 835.0 COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,4H9X5@91061|Bacilli 91061|Bacilli E o-acetylhomoserine metY - 2.5.1.49 ko:K01740 ko00270,ko01100,map00270,map01100 - R01287,R04859 RC00020,RC02821,RC02848 ko00000,ko00001,ko01000 - - - Cys_Met_Meta_PP BJHFPPGC_00570 1046629.Ssal_01088 0.0 1478.0 COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,4HB12@91061|Bacilli 91061|Bacilli L ATP-dependent DNA helicase pcrA - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C BJHFPPGC_00571 1046629.Ssal_01087 1.94e-304 832.0 COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,4H9SZ@91061|Bacilli 91061|Bacilli E (Alanine) symporter agcS - - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp BJHFPPGC_00572 904306.HMPREF9192_1757 5.44e-311 849.0 COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,4HA06@91061|Bacilli 91061|Bacilli S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 mnmE - - ko:K03650 - - R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 - - - MMR_HSR1,MnmE_helical,TrmE_N BJHFPPGC_00573 904306.HMPREF9192_1758 4.82e-219 605.0 COG2207@1|root,COG2207@2|Bacteria,1UZG6@1239|Firmicutes,4HCQS@91061|Bacilli 91061|Bacilli K Transcriptional regulator bglC - - - - - - - - - - - AraC_binding,HTH_18,HTH_AraC BJHFPPGC_00575 888808.HMPREF9380_1654 1.38e-12 76.3 29RP7@1|root,30CSI@2|Bacteria,1UAAN@1239|Firmicutes,4IKNF@91061|Bacilli,1WS1S@1305|Streptococcus sanguinis 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_00576 435842.HMPREF0848_01040 4.17e-233 650.0 COG0488@1|root,COG0488@2|Bacteria,1TU6J@1239|Firmicutes,4HDY2@91061|Bacilli 91061|Bacilli S abc transporter atp-binding protein XK27_10075 - - - - - - - - - - - ABC_tran BJHFPPGC_00577 1046629.Ssal_00665 0.0 1155.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein ndvA - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran BJHFPPGC_00578 904306.HMPREF9192_0998 0.0 1029.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H9SC@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein - - - ko:K06147,ko:K06148 - - - - ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran BJHFPPGC_00579 1046629.Ssal_00663 0.0 1473.0 COG1181@1|root,COG2918@1|root,COG1181@2|Bacteria,COG2918@2|Bacteria,1TPGX@1239|Firmicutes,4HAMJ@91061|Bacilli 91061|Bacilli H Belongs to the glutamate--cysteine ligase type 1 family gshF - 6.3.2.2 ko:K01919,ko:K16786,ko:K16787 ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010 M00118,M00582 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ATP-grasp_3,Dala_Dala_lig_C,GARS_A,Glu_cys_ligase BJHFPPGC_00581 1046629.Ssal_00660 0.0 975.0 2DI63@1|root,32UAI@2|Bacteria,1VBKU@1239|Firmicutes,4HUJH@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF3114) - - - - - - - - - - - - DUF1310,DUF3114 BJHFPPGC_00582 1046629.Ssal_00659 1.13e-131 373.0 COG0454@1|root,COG0456@2|Bacteria,1VEW7@1239|Firmicutes,4HPE4@91061|Bacilli 91061|Bacilli K Acetyltransferase GNAT Family - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_7 BJHFPPGC_00583 1046629.Ssal_00658 0.0 1588.0 COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,4H9XI@91061|Bacilli 91061|Bacilli G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties glgP GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 iYO844.BSU30940 Phosphorylase BJHFPPGC_00584 1046629.Ssal_00657 0.0 969.0 COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,4HAVA@91061|Bacilli 91061|Bacilli G Synthesizes alpha-1,4-glucan chains using ADP-glucose glgA GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 - GT5 - Glyco_transf_5,Glycos_transf_1 BJHFPPGC_00585 1046629.Ssal_00656 1.46e-232 644.0 COG0448@1|root,COG0448@2|Bacteria,1TPZ3@1239|Firmicutes,4H9UQ@91061|Bacilli 91061|Bacilli G glucose-1-phosphate adenylyltransferase glgD - 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transferase BJHFPPGC_00586 1046629.Ssal_00655 8.89e-251 691.0 COG0448@1|root,COG0448@2|Bacteria,1TNZW@1239|Firmicutes,4HAZX@91061|Bacilli 91061|Bacilli H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans glgC - 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transferase BJHFPPGC_00587 1046629.Ssal_00654 0.0 1325.0 COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,4HAPM@91061|Bacilli 91061|Bacilli G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position glgB GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000,ko04147 - CBM48,GH13 - Alpha-amylase,Alpha-amylase_C,CBM_48 BJHFPPGC_00588 1046629.Ssal_00653 0.0 1434.0 COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,4HBP5@91061|Bacilli 91061|Bacilli G belongs to the glycosyl hydrolase 13 family pulA - 3.2.1.41 ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 - R02111 - ko00000,ko00001,ko01000 - CBM48,GH13 - Alpha-amylase,CBM_48,PUD BJHFPPGC_00589 1046629.Ssal_00651 0.0 1447.0 COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,4H9WA@91061|Bacilli 91061|Bacilli D Belongs to the FtsK SpoIIIE SftA family ftsK GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma BJHFPPGC_00590 1046629.Ssal_00650 1.84e-237 653.0 COG0492@1|root,COG0492@2|Bacteria,1TRPN@1239|Firmicutes,4H9V7@91061|Bacilli 91061|Bacilli C Ferredoxin--NADP reductase yumC - 1.18.1.2,1.19.1.1 ko:K21567 - - - - ko00000,ko01000 - - iYO844.BSU32110 Pyr_redox_2 BJHFPPGC_00591 1046629.Ssal_00649 6.63e-173 482.0 COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,4HBFV@91061|Bacilli 91061|Bacilli J Belongs to the RNA methyltransferase TrmD family trmD GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 ko:K00554 - - R00597 RC00003,RC00334 ko00000,ko01000,ko03016 - - - tRNA_m1G_MT BJHFPPGC_00592 1046629.Ssal_00648 1.3e-121 347.0 COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,4HH3H@91061|Bacilli 91061|Bacilli J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes rimM - - ko:K02860 - - - - ko00000,ko03009 - - - PRC,RimM BJHFPPGC_00595 322159.STER_1387 5.45e-146 412.0 COG2197@1|root,COG2197@2|Bacteria,1TQ1U@1239|Firmicutes,4HA4B@91061|Bacilli 91061|Bacilli K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain vraR - - ko:K07694,ko:K11618 ko02020,map02020 M00480,M00481,M00754 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg BJHFPPGC_00596 904306.HMPREF9192_0961 3.44e-219 607.0 COG4585@1|root,COG4585@2|Bacteria,1TPDG@1239|Firmicutes,4HC7E@91061|Bacilli 91061|Bacilli T Histidine kinase vraS - 2.7.13.3 ko:K07681,ko:K11617 ko02020,map02020 M00480,M00481,M00754 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA_3 BJHFPPGC_00597 435842.HMPREF0848_01061 3.48e-151 426.0 COG4758@1|root,COG4758@2|Bacteria,1V3D0@1239|Firmicutes,4HDIA@91061|Bacilli 91061|Bacilli S Membrane yvqF - - ko:K11622 ko02020,map02020 - - - ko00000,ko00001 - - - DUF2154 BJHFPPGC_00598 1046629.Ssal_00644 3.14e-137 392.0 COG1226@1|root,COG1226@2|Bacteria,1V285@1239|Firmicutes,4I17E@91061|Bacilli 91061|Bacilli P Ion transport protein - - - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans,Ion_trans_2 BJHFPPGC_00599 1046629.Ssal_00643 0.0 1041.0 COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli 91061|Bacilli KLT serine threonine protein kinase prkC GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase BJHFPPGC_00600 1046629.Ssal_00642 2.2e-174 487.0 COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,4HCDR@91061|Bacilli 91061|Bacilli T phosphatase stp - 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C,PP2C_2 BJHFPPGC_00601 904306.HMPREF9192_0956 8.65e-310 845.0 COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1TP3N@1239|Firmicutes,4HBQ6@91061|Bacilli 91061|Bacilli J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA sun GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 ko:K03500 - - - - ko00000,ko01000,ko03009 - - - Methyltr_RsmB-F,Methyltr_RsmF_N,NusB BJHFPPGC_00602 435842.HMPREF0848_01065 1.12e-216 598.0 COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,4HART@91061|Bacilli 91061|Bacilli J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - iSB619.SA_RS06010 Formyl_trans_C,Formyl_trans_N BJHFPPGC_00603 1046629.Ssal_00638 0.0 1534.0 COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,4H9WW@91061|Bacilli 91061|Bacilli L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII BJHFPPGC_00604 1046629.Ssal_00637 1.37e-61 189.0 COG1758@1|root,COG1758@2|Bacteria 2|Bacteria K DNA-directed 5'-3' RNA polymerase activity rpoZ GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb6 BJHFPPGC_00605 1046629.Ssal_00636 1.45e-143 405.0 COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,4HAYW@91061|Bacilli 91061|Bacilli F Essential for recycling GMP and indirectly, cGMP gmk GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15680 Guanylate_kin BJHFPPGC_00606 1046629.Ssal_00633 1.51e-278 768.0 COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,4HA6A@91061|Bacilli 91061|Bacilli U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) ftsY - - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - SRP54,SRP54_N BJHFPPGC_00607 1046629.Ssal_00632 3.25e-185 516.0 COG0561@1|root,COG0561@2|Bacteria,1TR2E@1239|Firmicutes,4HGA9@91061|Bacilli 91061|Bacilli S overlaps another CDS with the same product name XK27_02985 - - - - - - - - - - - Hydrolase_3 BJHFPPGC_00608 1046629.Ssal_00631 3.54e-185 515.0 COG0561@1|root,COG0561@2|Bacteria,1V2JE@1239|Firmicutes,4IPK2@91061|Bacilli 91061|Bacilli S overlaps another CDS with the same product name - - - - - - - - - - - - Hydrolase_3 BJHFPPGC_00609 1046629.Ssal_00630 8.13e-82 242.0 COG1725@1|root,COG1725@2|Bacteria,1VFD0@1239|Firmicutes,4HNIT@91061|Bacilli 91061|Bacilli K Transcriptional ytrA - - ko:K07979 - - - - ko00000,ko03000 - - - GntR BJHFPPGC_00610 1046629.Ssal_00629 2.9e-159 447.0 COG1131@1|root,COG1131@2|Bacteria,1TPUP@1239|Firmicutes,4HGHM@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein skfE - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran BJHFPPGC_00611 1046629.Ssal_00628 3.17e-166 467.0 COG1131@1|root,COG1131@2|Bacteria,1VF25@1239|Firmicutes 1239|Firmicutes V Psort location CytoplasmicMembrane, score - - - - - - - - - - - - - BJHFPPGC_00612 1046629.Ssal_00627 1.94e-216 598.0 COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4HCM4@91061|Bacilli 91061|Bacilli P Belongs to the ABC transporter superfamily amiF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY BJHFPPGC_00613 904306.HMPREF9192_0944 1.34e-256 704.0 COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4H9MR@91061|Bacilli 91061|Bacilli P Belongs to the ABC transporter superfamily amiE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY BJHFPPGC_00614 1046629.Ssal_00625 1.92e-211 585.0 COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4HE8S@91061|Bacilli 91061|Bacilli P ABC transporter (Permease amiD - - ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1,OppC_N BJHFPPGC_00615 1046629.Ssal_00624 0.0 955.0 COG0601@1|root,COG0601@2|Bacteria,1UY5U@1239|Firmicutes,4HEZK@91061|Bacilli 91061|Bacilli P ABC transporter (Permease amiC GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1 BJHFPPGC_00616 1046629.Ssal_00622 0.0 1073.0 COG4166@1|root,COG4166@2|Bacteria,1TQVS@1239|Firmicutes,4HCCB@91061|Bacilli 91061|Bacilli E ABC transporter, substrate-binding protein, family 5 amiA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 BJHFPPGC_00617 904306.HMPREF9192_0941 0.0 1214.0 COG4166@1|root,COG4166@2|Bacteria,1TQVS@1239|Firmicutes,4HCCB@91061|Bacilli 91061|Bacilli E ABC transporter, substrate-binding protein, family 5 amiA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 BJHFPPGC_00618 904306.HMPREF9192_0940 1.13e-224 620.0 COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,4H9VH@91061|Bacilli 91061|Bacilli C phosphate acetyltransferase pta - 2.3.1.8,3.6.3.21 ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00236,M00357,M00579 R00230,R00921 RC00004,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 - iSB619.SA_RS03155 PTA_PTB BJHFPPGC_00619 904306.HMPREF9192_0939 3.5e-218 601.0 COG0564@1|root,COG0564@2|Bacteria,1TS1T@1239|Firmicutes,4HBRY@91061|Bacilli 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil yjbO GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2 BJHFPPGC_00620 264199.stu1457 5.67e-196 543.0 COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,4HB08@91061|Bacilli 91061|Bacilli H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - iSB619.SA_RS04895 NAD_kinase BJHFPPGC_00621 264199.stu1459 3.35e-153 431.0 COG2357@1|root,COG2357@2|Bacteria,1TQ2F@1239|Firmicutes,4HA3Q@91061|Bacilli 91061|Bacilli S Gtp pyrophosphokinase yjbM GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K07816 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - - RelA_SpoT BJHFPPGC_00622 904306.HMPREF9192_0936 4.76e-131 372.0 COG4116@1|root,COG4116@2|Bacteria,1VA56@1239|Firmicutes,4HMNE@91061|Bacilli 91061|Bacilli S Adenylate cyclase yjbK - - - - - - - - - - - CYTH BJHFPPGC_00623 1046629.Ssal_00616 7.94e-223 615.0 COG0462@1|root,COG0462@2|Bacteria,1TQ4I@1239|Firmicutes,4HDRN@91061|Bacilli 91061|Bacilli F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs2 - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran_N BJHFPPGC_00624 1046629.Ssal_00615 3.06e-262 719.0 COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,4HA6H@91061|Bacilli 91061|Bacilli E Cysteine desulfurase iscS - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 BJHFPPGC_00625 1046629.Ssal_00614 1.52e-79 236.0 2DHWG@1|root,32U9W@2|Bacteria,1VDSF@1239|Firmicutes,4HP9N@91061|Bacilli 91061|Bacilli S Putative amino acid metabolism XK27_04120 - - - - - - - - - - - DUF1831 BJHFPPGC_00626 1046629.Ssal_00613 1.1e-152 429.0 COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,4HB7Q@91061|Bacilli 91061|Bacilli K Modulates transcription in response to changes in cellular NADH NAD( ) redox state rex - - ko:K01926 - - - - ko00000,ko03000 - - - CoA_binding,Put_DNA-bind_N BJHFPPGC_00627 1046629.Ssal_00612 4.68e-169 471.0 COG2071@1|root,COG2071@2|Bacteria,1V1KC@1239|Firmicutes,4HI59@91061|Bacilli 91061|Bacilli T peptidase C26 - - - ko:K07010 - - - - ko00000,ko01002 - - - Peptidase_C26 BJHFPPGC_00628 322159.STER_1430 6.56e-154 433.0 COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,4HB1W@91061|Bacilli 91061|Bacilli E Belongs to the UPF0758 family radC - - ko:K03630 - - - - ko00000 - - - RadC BJHFPPGC_00629 1046629.Ssal_00610 0.0 962.0 COG3754@1|root,COG3754@2|Bacteria 2|Bacteria M Rhamnan synthesis protein F rgpF - - ko:K07272 - - - - ko00000,ko01000,ko01003,ko01005 - - - RgpF BJHFPPGC_00630 904306.HMPREF9192_0927 1.31e-285 780.0 COG1134@1|root,COG1134@2|Bacteria,1TQKK@1239|Firmicutes,4HC6N@91061|Bacilli 91061|Bacilli P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system rgpD - 3.6.3.40 ko:K01990,ko:K09691,ko:K09693 ko02010,map02010 M00250,M00251,M00254 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.103,3.A.1.104 - - ABC_tran,Wzt_C BJHFPPGC_00631 1046629.Ssal_00608 2.56e-180 503.0 COG1682@1|root,COG1682@2|Bacteria,1TY8I@1239|Firmicutes 1239|Firmicutes GM Transport permease protein - - - ko:K01992,ko:K09690,ko:K09692 ko02010,map02010 M00250,M00251,M00254 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.103,3.A.1.104 - - ABC2_membrane BJHFPPGC_00632 1046629.Ssal_00607 2.38e-223 615.0 COG0463@1|root,COG0463@2|Bacteria,1V7IQ@1239|Firmicutes,4HK7R@91061|Bacilli 91061|Bacilli M Glycosyltransferase, group 2 family protein rgpB - - ko:K12997 - - - - ko00000,ko01000,ko01003,ko01005 - GT2 - Glycos_transf_2 BJHFPPGC_00633 904306.HMPREF9192_0924 9.14e-286 779.0 COG0438@1|root,COG0438@2|Bacteria,1V7K7@1239|Firmicutes,4HA9A@91061|Bacilli 91061|Bacilli M Domain of unknown function (DUF1972) rgpA - - ko:K12996 - - - - ko00000,ko01000,ko01003,ko01005 - GT4 - DUF1972,Glycos_transf_1 BJHFPPGC_00634 1046629.Ssal_00603 2.54e-286 783.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - ko:K00754 - - - - ko00000,ko01000 - GT4 - Glyco_transf_4,Glycos_transf_1 BJHFPPGC_00635 904306.HMPREF9192_0922 1.91e-278 764.0 COG4713@1|root,COG4713@2|Bacteria 2|Bacteria M Psort location CytoplasmicMembrane, score - - - - - - - - - - - - DUF2142 BJHFPPGC_00636 1046629.Ssal_00601 0.0 1883.0 COG0438@1|root,COG1215@1|root,COG3754@1|root,COG0438@2|Bacteria,COG1215@2|Bacteria,COG3754@2|Bacteria,1UJI4@1239|Firmicutes,4HNC8@91061|Bacilli 91061|Bacilli M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 BJHFPPGC_00637 904306.HMPREF9192_0920 5.51e-195 539.0 COG1216@1|root,COG1216@2|Bacteria,1UI19@1239|Firmicutes 1239|Firmicutes S Glycosyltransferase group 2 family protein - - - - - - - - - - - - Glycos_transf_2 BJHFPPGC_00638 1046629.Ssal_00599 8.35e-59 183.0 2EVMS@1|root,33P1S@2|Bacteria,1VPQZ@1239|Firmicutes 1239|Firmicutes S Uncharacterized conserved protein (DUF2304) - - - ko:K09153 - - - - ko00000 - - - DUF2304 BJHFPPGC_00639 322159.STER_1440 2.1e-163 457.0 COG1215@1|root,COG1215@2|Bacteria,1UHQZ@1239|Firmicutes,4IS6R@91061|Bacilli 91061|Bacilli M group 2 family protein arnC - - ko:K00786 - - - - ko00000,ko01000 - - - Glycos_transf_2 BJHFPPGC_00640 862967.SIR_0956 2.14e-180 508.0 COG1442@1|root,COG1442@2|Bacteria,1UY8Y@1239|Firmicutes,4HBAE@91061|Bacilli,42DRT@671232|Streptococcus anginosus group 91061|Bacilli M Glycosyl transferase family 8 arbY - - - - - - - - - - - Glyco_transf_8 BJHFPPGC_00641 888048.HMPREF8577_0285 4.43e-208 587.0 COG2244@1|root,COG2244@2|Bacteria,1TTBW@1239|Firmicutes,4IR8C@91061|Bacilli 91061|Bacilli S polysaccharide biosynthetic process rgpX3 - - - - - - - - - - - Polysacc_synt BJHFPPGC_00642 873449.STRCR_1559 2.78e-103 330.0 COG5617@1|root,COG5617@2|Bacteria,1VS0Z@1239|Firmicutes,4HJQE@91061|Bacilli 91061|Bacilli S Psort location CytoplasmicMembrane, score - - - - - - - - - - - - - BJHFPPGC_00643 1046629.Ssal_00595 9.52e-204 563.0 COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,4HBXF@91061|Bacilli 91061|Bacilli M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose rfbD - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind BJHFPPGC_00644 322159.STER_1445 7.54e-273 751.0 COG4713@1|root,COG4713@2|Bacteria,1VTTT@1239|Firmicutes,4HW49@91061|Bacilli 91061|Bacilli S Predicted membrane protein (DUF2142) - - - - - - - - - - - - DUF2142 BJHFPPGC_00645 1046629.Ssal_00592 6.25e-217 599.0 COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,4HC2Z@91061|Bacilli 91061|Bacilli M COG0463, glycosyltransferases involved in cell wall biogenesis yfdH - - ko:K12999,ko:K20534 - - - - ko00000,ko01000,ko01003,ko01005,ko02000 4.D.2.1.9 GT2 - Glycos_transf_2 BJHFPPGC_00646 264199.stu1487 4.86e-74 222.0 COG2151@1|root,COG2151@2|Bacteria,1V9YV@1239|Firmicutes,4HKC6@91061|Bacilli 91061|Bacilli K metal-sulfur cluster biosynthetic enzyme yitW - - - - - - - - - - - FeS_assembly_P BJHFPPGC_00647 1046629.Ssal_00589 2.49e-256 704.0 COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,4HB1H@91061|Bacilli 91061|Bacilli K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth sigA - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 BJHFPPGC_00648 1046629.Ssal_00588 0.0 1155.0 COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,4HAG2@91061|Bacilli 91061|Bacilli L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 BJHFPPGC_00649 435842.HMPREF0848_01106 2.93e-65 201.0 COG1970@1|root,COG1970@2|Bacteria,1VA14@1239|Firmicutes,4HKIA@91061|Bacilli 91061|Bacilli M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell mscL - - ko:K03282 - - - - ko00000,ko02000 1.A.22.1 - - MscL BJHFPPGC_00650 1046629.Ssal_00586 8.61e-28 101.0 COG0828@1|root,COG0828@2|Bacteria,1VEHU@1239|Firmicutes,4HNPV@91061|Bacilli 91061|Bacilli J Belongs to the bacterial ribosomal protein bS21 family rpsU GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - ko:K02970 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S21 BJHFPPGC_00651 1046629.Ssal_00585 3.34e-174 487.0 COG0834@1|root,COG0834@2|Bacteria,1TT16@1239|Firmicutes,4HD16@91061|Bacilli 91061|Bacilli ET Belongs to the bacterial solute-binding protein 3 family artP - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 BJHFPPGC_00652 1046629.Ssal_00584 3.45e-263 721.0 COG0436@1|root,COG0436@2|Bacteria,1TQPD@1239|Firmicutes,4HE7P@91061|Bacilli 91061|Bacilli E Aminotransferase arcT - - - - - - - - - - - Aminotran_1_2 BJHFPPGC_00653 1046629.Ssal_00583 8.55e-175 489.0 COG0834@1|root,COG0834@2|Bacteria,1TT16@1239|Firmicutes 1239|Firmicutes ET Belongs to the bacterial solute-binding protein 3 family - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 BJHFPPGC_00654 1046629.Ssal_00582 8.2e-178 497.0 COG0834@1|root,COG0834@2|Bacteria,1TT16@1239|Firmicutes,4HJ2R@91061|Bacilli 91061|Bacilli ET ABC transporter XK27_04395 - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 BJHFPPGC_00655 435842.HMPREF0848_01112 2.51e-108 311.0 COG1051@1|root,COG1051@2|Bacteria,1V3MM@1239|Firmicutes 1239|Firmicutes F Nudix family XK27_04400 - 3.6.1.55 ko:K03574,ko:K12944 - - - - ko00000,ko01000,ko03400 - - - NUDIX BJHFPPGC_00656 1046629.Ssal_00577 0.0 1275.0 COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,4HB81@91061|Bacilli 91061|Bacilli L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB - - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB BJHFPPGC_00658 904306.HMPREF9192_0897 2.48e-204 567.0 COG1266@1|root,COG1266@2|Bacteria,1VA8S@1239|Firmicutes,4IQWI@91061|Bacilli 91061|Bacilli S CAAX amino terminal protease family protein - - - ko:K07052 - - - - ko00000 - - - Abi BJHFPPGC_00659 1046629.Ssal_00574 0.0 1379.0 COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,1TQUG@1239|Firmicutes,4HAJ5@91061|Bacilli 91061|Bacilli P ABC-type amino acid transport signal transduction systems periplasmic component domain glnP - - ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 M00227,M00236 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.2 - - BPD_transp_1,SBP_bac_3 BJHFPPGC_00660 1046629.Ssal_00573 4.14e-175 488.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli 91061|Bacilli E abc transporter atp-binding protein glnQ - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran BJHFPPGC_00661 1321372.AQQB01000060_gene15 5.23e-25 94.4 29R2M@1|root,30C3R@2|Bacteria,1U94Q@1239|Firmicutes,4IJ5T@91061|Bacilli,1WTRS@1307|Streptococcus suis 91061|Bacilli - - XK27_00735 - - - - - - - - - - - - BJHFPPGC_00662 904306.HMPREF9192_0893 7.8e-315 857.0 COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,4H9P8@91061|Bacilli 91061|Bacilli S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg GO:0000003,GO:0000160,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0017076,GO:0019001,GO:0019954,GO:0023052,GO:0030436,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035556,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043934,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - DUF1967,GTP1_OBG,MMR_HSR1 BJHFPPGC_00663 388919.SSA_0806 9.86e-10 54.3 29RNI@1|root,30CRU@2|Bacteria,1UA9S@1239|Firmicutes,4IKMB@91061|Bacilli,1WS04@1305|Streptococcus sanguinis 91061|Bacilli S Protein of unknown function (DUF4044) - - - - - - - - - - - - DUF4044 BJHFPPGC_00664 1046629.Ssal_00568 2.1e-162 456.0 COG1187@1|root,COG1187@2|Bacteria,1TQZ2@1239|Firmicutes,4H9VU@91061|Bacilli 91061|Bacilli J Belongs to the pseudouridine synthase RsuA family rsuA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19 ko:K06183 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 BJHFPPGC_00665 883156.HMPREF9282_01673 2.59e-10 69.3 COG1397@1|root,COG1397@2|Bacteria,1V7HC@1239|Firmicutes,4H7XK@909932|Negativicutes 909932|Negativicutes O ADP-ribosylglycohydrolase - - - - - - - - - - - - - BJHFPPGC_00666 264199.stu1516 6.67e-81 241.0 COG2050@1|root,COG2050@2|Bacteria,1VN0K@1239|Firmicutes,4HM66@91061|Bacilli 91061|Bacilli Q protein possibly involved in aromatic compounds catabolism - - - ko:K02614 ko00360,map00360 - R09840 RC00004,RC00014 ko00000,ko00001,ko01000 - - - 4HBT BJHFPPGC_00667 1046629.Ssal_00565 8.58e-82 242.0 COG1765@1|root,COG1765@2|Bacteria 2|Bacteria O OsmC-like protein ycaO - - ko:K06889,ko:K07397,ko:K09136 - - - - ko00000,ko03009 - - - Hydrolase_4,OsmC,YcaO BJHFPPGC_00669 1046629.Ssal_00562 1.36e-189 529.0 COG0697@1|root,COG0697@2|Bacteria,1TYSF@1239|Firmicutes 1239|Firmicutes EG Permeases of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA BJHFPPGC_00671 1046629.Ssal_00560 3.26e-143 405.0 COG0560@1|root,COG0560@2|Bacteria,1V9R7@1239|Firmicutes,4HTNE@91061|Bacilli 91061|Bacilli E phosphoserine phosphatase serB - 3.1.3.3 ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R00582 RC00017 ko00000,ko00001,ko00002,ko01000,ko01009 - - - HAD BJHFPPGC_00672 1046629.Ssal_00559 0.0 1044.0 COG4477@1|root,COG4477@2|Bacteria,1TQR7@1239|Firmicutes,4HA15@91061|Bacilli 91061|Bacilli D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization ezrA GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000921,GO:0005575,GO:0005623,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0022402,GO:0022607,GO:0031106,GO:0032185,GO:0032506,GO:0034622,GO:0043933,GO:0044085,GO:0044464,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051301,GO:0051302,GO:0051781,GO:0061640,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 - ko:K06286 - - - - ko00000,ko03036 - - - EzrA BJHFPPGC_00673 1046629.Ssal_00558 0.0 1268.0 COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,4H9Y6@91061|Bacilli 91061|Bacilli L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim BJHFPPGC_00674 1046629.Ssal_00557 6.95e-125 357.0 COG0546@1|root,COG0546@2|Bacteria,1V421@1239|Firmicutes,4HHYH@91061|Bacilli 91061|Bacilli S IA, variant 1 - - - - - - - - - - - - HAD_2 BJHFPPGC_00675 904306.HMPREF9192_0878 3.76e-150 424.0 COG1346@1|root,COG1346@2|Bacteria,1TRGN@1239|Firmicutes 1239|Firmicutes M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses lrgB - - - - - - - - - - - LrgB BJHFPPGC_00676 322159.STER_1483 9.16e-74 222.0 COG1380@1|root,COG1380@2|Bacteria,1VEN4@1239|Firmicutes 1239|Firmicutes S Effector of murein hydrolase LrgA lrgA - - ko:K06518 - - - - ko00000,ko02000 1.E.14.2 - - LrgA BJHFPPGC_00678 1046629.Ssal_01688 1.19e-77 231.0 COG1393@1|root,COG1393@2|Bacteria,1VA5Q@1239|Firmicutes,4HKQQ@91061|Bacilli 91061|Bacilli P Belongs to the ArsC family yusI - 1.20.4.1 ko:K00537 - - - - ko00000,ko01000 - - - ArsC,Glutaredoxin BJHFPPGC_00679 904306.HMPREF9192_0874 1.33e-92 273.0 COG0350@1|root,COG0350@2|Bacteria 2|Bacteria L methylated-DNA-[protein]-cysteine S-methyltransferase activity ogt GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 2.1.1.63,3.2.2.20 ko:K00567,ko:K01246 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - DNA_binding_1,Methyltransf_1N BJHFPPGC_00680 1046629.Ssal_00539 2.4e-277 759.0 COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,4H9PH@91061|Bacilli 91061|Bacilli EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family serA - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C,ACT_4 BJHFPPGC_00681 904306.HMPREF9192_0872 4.45e-133 377.0 COG1247@1|root,COG1247@2|Bacteria,1UIW7@1239|Firmicutes,4ISU9@91061|Bacilli 91061|Bacilli M Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 BJHFPPGC_00682 1046629.Ssal_00537 4.21e-266 728.0 COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,4HATT@91061|Bacilli 91061|Bacilli E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine serC GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 BJHFPPGC_00683 1046629.Ssal_00536 1.72e-193 539.0 COG1940@1|root,COG1940@2|Bacteria,1TRQ7@1239|Firmicutes,4HE30@91061|Bacilli 91061|Bacilli GK ROK family - - - - - - - - - - - - ROK BJHFPPGC_00684 904306.HMPREF9192_0869 1.37e-92 270.0 COG0346@1|root,COG0346@2|Bacteria,1V6K3@1239|Firmicutes,4HJ7X@91061|Bacilli 91061|Bacilli E Lactoylglutathione lyase gloA - 4.4.1.5 ko:K01759,ko:K15772 ko00620,ko02010,map00620,map02010 M00491 R02530 RC00004,RC00740 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.1.16,3.A.1.1.2 - - Glyoxalase BJHFPPGC_00685 904306.HMPREF9192_0867 1.37e-195 544.0 COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,4HGRC@91061|Bacilli 91061|Bacilli O HflC and HflK could regulate a protease hflC - - ko:K04087 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7 BJHFPPGC_00686 904306.HMPREF9192_0865 1.29e-260 713.0 COG0687@1|root,COG0687@2|Bacteria,1TPY1@1239|Firmicutes,4HAET@91061|Bacilli 91061|Bacilli P spermidine putrescine ABC transporter potD - - ko:K11069 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 - iSB619.SA_RS05395 SBP_bac_8 BJHFPPGC_00687 322159.STER_1494 1.92e-166 467.0 COG1177@1|root,COG1177@2|Bacteria,1V0VD@1239|Firmicutes,4H9ZC@91061|Bacilli 91061|Bacilli P ABC-type spermidine putrescine transport system, permease component II potC - - ko:K11070 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 - - BPD_transp_1 BJHFPPGC_00688 435842.HMPREF0848_01147 4.91e-180 502.0 COG1176@1|root,COG1176@2|Bacteria,1TQ7Z@1239|Firmicutes,4HAYS@91061|Bacilli 91061|Bacilli P ABC-type spermidine putrescine transport system, permease component I potB - - ko:K11071 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 - - BPD_transp_1 BJHFPPGC_00689 904306.HMPREF9192_0862 9.28e-271 741.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4H9MS@91061|Bacilli 91061|Bacilli P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system potA - 3.6.3.30,3.6.3.31 ko:K02010,ko:K11072 ko02010,map02010 M00190,M00299 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10,3.A.1.11.1 - iSB619.SA_RS05380 ABC_tran,TOBE_2 BJHFPPGC_00690 1046629.Ssal_00526 1.04e-211 586.0 COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,4HAD8@91061|Bacilli 91061|Bacilli M cell wall formation murB - 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - - FAD_binding_4,MurB_C BJHFPPGC_00691 1046629.Ssal_00525 3.5e-101 294.0 COG0801@1|root,COG0801@2|Bacteria,1V6PR@1239|Firmicutes,4HIMG@91061|Bacilli 91061|Bacilli H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK - 2.7.6.3 ko:K00950 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HPPK BJHFPPGC_00692 1046629.Ssal_00524 9.73e-78 231.0 COG1539@1|root,COG1539@2|Bacteria,1VA0I@1239|Firmicutes,4HKKK@91061|Bacilli 91061|Bacilli H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin folB - 1.13.11.81,4.1.2.25,5.1.99.8 ko:K01633 ko00790,ko01100,map00790,map01100 M00126,M00840 R03504,R11037,R11073 RC00721,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 - - - FolB BJHFPPGC_00693 435842.HMPREF0848_01152 0.0 1004.0 COG0366@1|root,COG0366@2|Bacteria,1TRKZ@1239|Firmicutes,4HC8C@91061|Bacilli 91061|Bacilli G Belongs to the glycosyl hydrolase 13 family amy - 3.2.1.1 ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 - R02108,R02112,R11262 - ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,DUF1939 BJHFPPGC_00694 1046629.Ssal_00522 3.54e-186 518.0 COG0294@1|root,COG0294@2|Bacteria,1TPKT@1239|Firmicutes,4H9SY@91061|Bacilli 91061|Bacilli H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives folP GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 ko:K00796 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 - - - Pterin_bind BJHFPPGC_00695 1046629.Ssal_00521 8.12e-129 366.0 COG0302@1|root,COG0302@2|Bacteria,1TRNM@1239|Firmicutes,4HAXS@91061|Bacilli 91061|Bacilli F gtp cyclohydrolase folE GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydroI BJHFPPGC_00696 1046629.Ssal_00520 0.0 1173.0 COG0531@1|root,COG0531@2|Bacteria,1TQE1@1239|Firmicutes,4HAZH@91061|Bacilli 91061|Bacilli E amino acid ydaO GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - - - - - - - - - - AA_permease_2 BJHFPPGC_00697 1046629.Ssal_00519 2.41e-298 814.0 COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,4HBJM@91061|Bacilli 91061|Bacilli H Belongs to the folylpolyglutamate synthase family folC - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS08370 Mur_ligase_C,Mur_ligase_M BJHFPPGC_00698 1046629.Ssal_00518 3.71e-49 156.0 COG1837@1|root,COG1837@2|Bacteria 2|Bacteria L Belongs to the UPF0109 family ylqC - - ko:K06960 - - - - ko00000 - - - KH_4 BJHFPPGC_00699 1046629.Ssal_00517 1.87e-57 178.0 COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,4HKNN@91061|Bacilli 91061|Bacilli J Belongs to the bacterial ribosomal protein bS16 family rpsP GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02959 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S16 BJHFPPGC_00701 435842.HMPREF0848_01160 2.28e-269 743.0 COG3290@1|root,COG3290@2|Bacteria 2|Bacteria T protein histidine kinase activity - - 2.7.13.3 ko:K07706 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c_5,PAS_9 BJHFPPGC_00702 1046629.Ssal_00514 6.45e-158 444.0 COG3279@1|root,COG3279@2|Bacteria 2|Bacteria KT phosphorelay signal transduction system agrA - - ko:K07707 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg BJHFPPGC_00703 1046629.Ssal_00513 3.5e-230 643.0 COG5549@1|root,COG5549@2|Bacteria 2|Bacteria O protein import - - - - - - - - - - - - Peptidase_M10 BJHFPPGC_00704 904306.HMPREF9192_0841 1.31e-210 582.0 COG0500@1|root,COG3615@1|root,COG0500@2|Bacteria,COG3615@2|Bacteria,1TSZK@1239|Firmicutes,4HJT1@91061|Bacilli 91061|Bacilli PQ tellurite resistance protein tehb tehB - 2.1.1.265 ko:K16868 - - - - ko00000,ko01000 - - - DUF1971,TehB BJHFPPGC_00705 888833.HMPREF9421_1657 6.14e-12 67.0 2DMBI@1|root,32H42@2|Bacteria,1VFT3@1239|Firmicutes,4HK1A@91061|Bacilli 91061|Bacilli S Domain of unknown function (DUF4767) yjdB - - - - - - - - - - - DUF4767 BJHFPPGC_00708 1046629.Ssal_00508 2.43e-202 559.0 COG0708@1|root,COG0708@2|Bacteria,1TPFB@1239|Firmicutes,4HAIU@91061|Bacilli 91061|Bacilli L exodeoxyribonuclease III xth GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008296,GO:0008309,GO:0008311,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos BJHFPPGC_00709 1046629.Ssal_00507 2.17e-91 269.0 COG4708@1|root,COG4708@2|Bacteria,1V99E@1239|Firmicutes,4HXAN@91061|Bacilli 91061|Bacilli S QueT transporter - - - - - - - - - - - - QueT BJHFPPGC_00711 1046629.Ssal_00505 2.1e-223 617.0 COG2378@1|root,COG2378@2|Bacteria 2|Bacteria K regulation of single-species biofilm formation yfjR GO:0008150,GO:0043900,GO:0050789,GO:0050794,GO:0065007,GO:1900190 - - - - - - - - - - HTH_11,HTH_DeoR,WYL BJHFPPGC_00715 1046629.Ssal_00504 4.51e-236 650.0 COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes,4H9WD@91061|Bacilli 91061|Bacilli I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase dagK GO:0003674,GO:0003824,GO:0004143,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237 2.7.1.107 ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 - R02240 RC00002,RC00017 ko00000,ko00001,ko01000 - - - DAGK_cat BJHFPPGC_00716 904306.HMPREF9192_0832 0.0 1227.0 COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,4HA1D@91061|Bacilli 91061|Bacilli L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 BJHFPPGC_00717 1046629.Ssal_00502 9.88e-111 319.0 COG4708@1|root,COG4708@2|Bacteria,1V22G@1239|Firmicutes,4HGG2@91061|Bacilli 91061|Bacilli S cog cog4708 ccl GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - QueT BJHFPPGC_00718 1046629.Ssal_00501 2.48e-205 570.0 COG1295@1|root,COG1295@2|Bacteria,1U7HM@1239|Firmicutes,4H9MJ@91061|Bacilli 91061|Bacilli E Belongs to the UPF0761 family rbn - - ko:K07058 - - - - ko00000 - - - Virul_fac_BrkB BJHFPPGC_00719 1046629.Ssal_00500 4.94e-212 585.0 COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H9S9@91061|Bacilli 91061|Bacilli E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed map - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 BJHFPPGC_00720 1046629.Ssal_00499 5.02e-294 804.0 COG4109@1|root,COG4109@2|Bacteria,1TPU6@1239|Firmicutes,4HB62@91061|Bacilli 91061|Bacilli K transcriptional regulator containing CBS domains ytoI - - - - - - - - - - - 4HBT,CBS,DRTGG,GntR,HTH_24 BJHFPPGC_00721 1046629.Ssal_00498 1.14e-124 355.0 COG1670@1|root,COG1670@2|Bacteria,1V576@1239|Firmicutes,4HH6U@91061|Bacilli 91061|Bacilli J Acetyltransferase GNAT Family XK27_07830 - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 BJHFPPGC_00722 1046629.Ssal_00497 1.49e-292 800.0 COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,4H9KI@91061|Bacilli 91061|Bacilli M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042221,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0070589,GO:0070887,GO:0071236,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - iYO844.BSU37100 EPSP_synthase BJHFPPGC_00723 1046629.Ssal_00495 0.0 1393.0 COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,4H9M4@91061|Bacilli 91061|Bacilli S Competence protein ComEC comEC - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B BJHFPPGC_00724 1046629.Ssal_00493 1.81e-125 361.0 COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,4HKJ1@91061|Bacilli 91061|Bacilli L COG1555 DNA uptake protein and related DNA-binding proteins comEA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02237 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - HHH_3,SLBB BJHFPPGC_00725 264199.stu1563 1.45e-182 507.0 COG0204@1|root,COG0204@2|Bacteria,1U8N2@1239|Firmicutes,4HDQR@91061|Bacilli 91061|Bacilli I Acyltransferase plsC GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008374,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0042171,GO:0044464,GO:0071617,GO:0071944 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase BJHFPPGC_00726 435842.HMPREF0848_01183 4.13e-199 555.0 COG0726@1|root,COG0726@2|Bacteria,1TYRH@1239|Firmicutes,4HHQN@91061|Bacilli 91061|Bacilli G deacetylase nodB3 - - - - - - - - - - - Polysacc_deac_1 BJHFPPGC_00727 1046629.Ssal_00490 5.87e-179 498.0 COG4123@1|root,COG4123@2|Bacteria,1TQ25@1239|Firmicutes,4HA8W@91061|Bacilli 91061|Bacilli L Methyltransferase yabB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.223 ko:K07461,ko:K15460 - - - - ko00000,ko01000,ko03016 - - - GIY-YIG,MTS BJHFPPGC_00728 435842.HMPREF0848_01185 2.9e-56 175.0 COG2827@1|root,COG2827@2|Bacteria,1VEZF@1239|Firmicutes,4HNHJ@91061|Bacilli 91061|Bacilli L endonuclease containing a URI domain yazA - - ko:K07461 - - - - ko00000 - - - GIY-YIG BJHFPPGC_00729 435842.HMPREF0848_01186 0.0 932.0 COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HAB3@91061|Bacilli 91061|Bacilli JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity cshA GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,Helicase_C BJHFPPGC_00730 435842.HMPREF0848_01187 9.03e-202 560.0 COG0598@1|root,COG0598@2|Bacteria,1TPI8@1239|Firmicutes,4HCQ6@91061|Bacilli 91061|Bacilli P CorA-like protein corA - - - - - - - - - - - CorA BJHFPPGC_00731 435842.HMPREF0848_01188 3.05e-82 243.0 arCOG12631@1|root,3172B@2|Bacteria,1V77G@1239|Firmicutes,4HJ0W@91061|Bacilli 91061|Bacilli S Bacterial PH domain yjqA - - - - - - - - - - - bPH_1 BJHFPPGC_00732 1046629.Ssal_00485 2.84e-123 352.0 COG3859@1|root,COG3859@2|Bacteria,1V6YE@1239|Firmicutes,4HIJE@91061|Bacilli 91061|Bacilli S Thiamine transporter thiT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K16789 - - - - ko00000,ko02000 2.A.88.3 - - Thia_YuaJ BJHFPPGC_00733 264199.stu1572 2.06e-200 555.0 COG1396@1|root,COG1396@2|Bacteria,1UZI0@1239|Firmicutes,4HC2C@91061|Bacilli 91061|Bacilli K Transcriptional activator, Rgg GadR MutR family rgg - - - - - - - - - - - HTH_3 BJHFPPGC_00734 322159.STER_1531 2.74e-251 693.0 COG2211@1|root,COG2211@2|Bacteria,1TR4D@1239|Firmicutes,4HDCY@91061|Bacilli 91061|Bacilli G Permeases of the major facilitator superfamily yjbB - - - - - - - - - - - MFS_1,MFS_3 BJHFPPGC_00735 1046629.Ssal_00481 0.0 1031.0 COG4108@1|root,COG4108@2|Bacteria,1TPYT@1239|Firmicutes,4HADS@91061|Bacilli 91061|Bacilli J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP prfC GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02837 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,RF3_C BJHFPPGC_00737 1046629.Ssal_00479 6.1e-151 425.0 COG5522@1|root,COG5522@2|Bacteria 2|Bacteria S Integral membrane protein (intg_mem_TP0381) ywaF - - - - - - - - - - - Intg_mem_TP0381 BJHFPPGC_00739 585204.SMSK597_0480 2.22e-24 107.0 COG1396@1|root,COG1396@2|Bacteria,1V957@1239|Firmicutes,4IEDW@91061|Bacilli,2TQ2P@28037|Streptococcus mitis 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3 BJHFPPGC_00740 435842.HMPREF0848_01611 1.88e-43 152.0 COG3633@1|root,COG3633@2|Bacteria,1TPD2@1239|Firmicutes,4HBEC@91061|Bacilli 91061|Bacilli E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) sstT - - ko:K07862 - - - - ko00000,ko02000 2.A.23.4 - - SDF BJHFPPGC_00741 904306.HMPREF9192_0808 0.0 872.0 COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,4HACR@91061|Bacilli 91061|Bacilli M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M BJHFPPGC_00744 1316408.HSISM1_1339 0.000218 51.6 COG2339@1|root,COG2339@2|Bacteria,1UDJA@1239|Firmicutes,4HBTX@91061|Bacilli 91061|Bacilli S membrane - - - - - - - - - - - - DUF4339,PrsW-protease,zinc_ribbon_2 BJHFPPGC_00745 1316408.HSISM1_1339 3.85e-05 53.9 COG2339@1|root,COG2339@2|Bacteria,1UDJA@1239|Firmicutes,4HBTX@91061|Bacilli 91061|Bacilli S membrane - - - - - - - - - - - - DUF4339,PrsW-protease,zinc_ribbon_2 BJHFPPGC_00746 1316408.HSISM1_1339 0.000126 52.4 COG2339@1|root,COG2339@2|Bacteria,1UDJA@1239|Firmicutes,4HBTX@91061|Bacilli 91061|Bacilli S membrane - - - - - - - - - - - - DUF4339,PrsW-protease,zinc_ribbon_2 BJHFPPGC_00747 904306.HMPREF9192_0805 7.77e-199 551.0 COG0834@1|root,COG0834@2|Bacteria,1TT11@1239|Firmicutes,4HFBQ@91061|Bacilli 91061|Bacilli ET ABC transporter substrate-binding protein cjaA - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 BJHFPPGC_00748 1046629.Ssal_00475 3.65e-172 481.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4HDK7@91061|Bacilli 91061|Bacilli E abc transporter atp-binding protein glnQ - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran BJHFPPGC_00749 1046629.Ssal_00474 9.28e-148 417.0 COG0765@1|root,COG0765@2|Bacteria,1TR7R@1239|Firmicutes,4HGVA@91061|Bacilli 91061|Bacilli P ABC transporter (Permease glnP7 - - ko:K02029 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 BJHFPPGC_00750 1046629.Ssal_00473 3.49e-148 418.0 COG0765@1|root,COG0765@2|Bacteria,1TRU3@1239|Firmicutes,4HGE1@91061|Bacilli 91061|Bacilli P ABC transporter (Permease glnP9 - - ko:K02029 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 BJHFPPGC_00751 904306.HMPREF9192_0803 1.08e-244 672.0 COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,4H9KB@91061|Bacilli 91061|Bacilli F Belongs to the D-alanine--D-alanine ligase family ddl - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N BJHFPPGC_00752 435842.HMPREF0848_01205 2.72e-42 138.0 COG2608@1|root,COG2608@2|Bacteria,1VK5F@1239|Firmicutes,4HR1Z@91061|Bacilli 91061|Bacilli P Heavy metal-associated domain protein copZ - - - - - - - - - - - HMA BJHFPPGC_00753 435842.HMPREF0848_01206 0.0 1326.0 COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,4HAI0@91061|Bacilli 91061|Bacilli P P-type ATPase copA - 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase BJHFPPGC_00754 435842.HMPREF0848_01207 1.49e-97 283.0 COG3682@1|root,COG3682@2|Bacteria 2|Bacteria K negative regulation of transcription, DNA-templated copY - - - - - - - - - - - Penicillinase_R BJHFPPGC_00757 1046629.Ssal_00465 3.39e-181 504.0 COG0159@1|root,COG0159@2|Bacteria,1TPXA@1239|Firmicutes,4HFQ8@91061|Bacilli 91061|Bacilli E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate trpA - 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - Trp_syntA BJHFPPGC_00758 1046629.Ssal_00464 1.22e-291 796.0 COG0133@1|root,COG0133@2|Bacteria,1TPI3@1239|Firmicutes,4H9WC@91061|Bacilli 91061|Bacilli E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine trpB GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20,5.3.1.24 ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722,R03509 RC00209,RC00210,RC00700,RC00701,RC00945,RC02868 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU22640 PALP BJHFPPGC_00759 904306.HMPREF9192_0790 1.78e-127 363.0 COG0135@1|root,COG0135@2|Bacteria,1V6Y0@1239|Firmicutes,4HK18@91061|Bacilli 91061|Bacilli E belongs to the TrpF family trpF - 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 - - - PRAI BJHFPPGC_00760 322159.STER_1551 4.4e-170 476.0 COG0134@1|root,COG0134@2|Bacteria,1TR94@1239|Firmicutes,4HG9K@91061|Bacilli 91061|Bacilli E Belongs to the TrpC family trpC GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 ko:K01609 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03508 RC00944 ko00000,ko00001,ko00002,ko01000 - - - IGPS BJHFPPGC_00761 904306.HMPREF9192_0788 1.05e-228 631.0 COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,4H9KQ@91061|Bacilli 91061|Bacilli F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0004425,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R00985,R00986,R01073 RC00010,RC00440,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Glycos_trans_3N,Glycos_transf_3 BJHFPPGC_00762 1046629.Ssal_00458 1.61e-132 375.0 COG0512@1|root,COG0512@2|Bacteria,1V4RM@1239|Firmicutes,4HHD8@91061|Bacilli 91061|Bacilli EH anthranilate trpG - 4.1.3.27 ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - GATase BJHFPPGC_00763 904306.HMPREF9192_0786 0.0 883.0 COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,4HB31@91061|Bacilli 91061|Bacilli EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia trpE GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind BJHFPPGC_00764 322159.STER_1555 3.07e-53 167.0 COG1605@1|root,COG1605@2|Bacteria 2|Bacteria E Chorismate mutase MA20_20425 - 2.5.1.19,4.2.1.10,4.2.99.21,5.4.99.5 ko:K00800,ko:K03785,ko:K04092,ko:K04782 ko00400,ko01053,ko01100,ko01110,ko01130,ko01230,map00400,map01053,map01100,map01110,map01130,map01230 M00022,M00024,M00025 R01715,R03084,R03460,R06602 RC00350,RC00848,RC01549,RC02148,RC03116 ko00000,ko00001,ko00002,ko01000 - - - CM_2 BJHFPPGC_00765 1046629.Ssal_00451 3.24e-77 230.0 2C4MC@1|root,32RSW@2|Bacteria,1VCIA@1239|Firmicutes,4HKKA@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_00766 904306.HMPREF9192_0784 0.0 1469.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9ZI@91061|Bacilli 91061|Bacilli P E1-E2 ATPase ctpE - - ko:K12952 - - - - ko00000,ko01000 3.A.3.23 - - E1-E2_ATPase,Hydrolase BJHFPPGC_00767 563038.HMPREF0851_01447 1.29e-56 182.0 2DEIC@1|root,2ZN3X@2|Bacteria,1W3A8@1239|Firmicutes,4HZMP@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_00768 1046629.Ssal_01235 3.28e-15 74.7 COG0381@1|root,COG0381@2|Bacteria,1TQZT@1239|Firmicutes,4HBI3@91061|Bacilli 91061|Bacilli G Belongs to the UDP-N-acetylglucosamine 2-epimerase family mnaA - 5.1.3.14 ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420 RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 - - iSB619.SA_RS11005 Epimerase_2 BJHFPPGC_00769 435842.HMPREF0848_01223 4.78e-223 616.0 COG2199@1|root,COG2199@2|Bacteria,1UQA9@1239|Firmicutes,4HBNE@91061|Bacilli 91061|Bacilli T Diguanylate cyclase - - - - - - - - - - - - GGDEF,PAS_4,PAS_9 BJHFPPGC_00770 435842.HMPREF0848_01224 1.72e-214 597.0 COG0463@1|root,COG2246@1|root,COG0463@2|Bacteria,COG2246@2|Bacteria,1TQ8C@1239|Firmicutes,4HDD4@91061|Bacilli 91061|Bacilli M COG0463, glycosyltransferases involved in cell wall biogenesis - - - - - - - - - - - - Glycos_transf_2,GtrA BJHFPPGC_00771 435842.HMPREF0848_01225 0.0 1493.0 COG1215@1|root,COG1215@2|Bacteria,1TSD3@1239|Firmicutes,4HD23@91061|Bacilli 91061|Bacilli M COG1215 Glycosyltransferases, probably involved in cell wall biogenesis - - 2.4.1.12 ko:K00694 ko00500,ko01100,ko02026,map00500,map01100,map02026 - R02889 RC00005 ko00000,ko00001,ko01000,ko01003,ko02000 4.D.3.1.2,4.D.3.1.5,4.D.3.1.6 GT2 - Cellulose_synt,Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2,PilZ BJHFPPGC_00772 435842.HMPREF0848_01226 0.0 1142.0 28KEZ@1|root,2ZA17@2|Bacteria,1TPQ9@1239|Firmicutes,4HFER@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_00773 873447.SPB_1682 3.11e-30 117.0 COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4HA1P@91061|Bacilli 91061|Bacilli L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII polYB - 2.7.7.7 ko:K02346,ko:K03502 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH BJHFPPGC_00774 435842.HMPREF0848_01227 2.63e-104 301.0 2F0Z4@1|root,33U0S@2|Bacteria,1VUJF@1239|Firmicutes,4I1M0@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_00775 435842.HMPREF0848_01228 2.08e-143 406.0 COG2932@1|root,COG2932@2|Bacteria,1TQWX@1239|Firmicutes,4HY19@91061|Bacilli 91061|Bacilli K Peptidase S24-like protein - - - - - - - - - - - - HTH_3,Peptidase_S24 BJHFPPGC_00776 435842.HMPREF0848_01229 2.63e-166 468.0 COG2856@1|root,COG2856@2|Bacteria,1VPKW@1239|Firmicutes,4HZKQ@91061|Bacilli 91061|Bacilli E IrrE N-terminal-like domain - - - - - - - - - - - - Peptidase_M78 BJHFPPGC_00777 1035189.HMPREF9954_1729 1.92e-116 341.0 2EDPB@1|root,337J0@2|Bacteria,1VV0W@1239|Firmicutes,4HVVE@91061|Bacilli,43GDQ@68892|Streptococcus infantis 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_00778 562983.HMPREF0433_00672 2.19e-101 306.0 2F5IH@1|root,33Y3W@2|Bacteria,1VWCK@1239|Firmicutes,4HW3I@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_00779 563038.HMPREF0851_01447 4.69e-61 193.0 2DEIC@1|root,2ZN3X@2|Bacteria,1W3A8@1239|Firmicutes,4HZMP@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_00780 264199.stu1598 1.52e-58 181.0 COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,4HKH3@91061|Bacilli 91061|Bacilli S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection yaaK - - ko:K09747 - - - - ko00000 - - - YbaB_DNA_bd BJHFPPGC_00782 1046629.Ssal_00444 1.59e-160 450.0 COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,4HB8D@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran BJHFPPGC_00783 1046629.Ssal_00443 0.0 1602.0 COG0577@1|root,COG0577@2|Bacteria,1TPHU@1239|Firmicutes,4HA2C@91061|Bacilli 91061|Bacilli V ABC transporter (Permease - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD BJHFPPGC_00784 435842.HMPREF0848_01235 7.9e-165 462.0 COG0789@1|root,COG0789@2|Bacteria,1UZ0H@1239|Firmicutes,4HGGU@91061|Bacilli 91061|Bacilli K transcriptional regulator, MerR family - - - - - - - - - - - - MerR_1 BJHFPPGC_00785 904306.HMPREF9192_0778 5.33e-135 382.0 COG0847@1|root,COG0847@2|Bacteria,1V8EQ@1239|Firmicutes,4HJYT@91061|Bacilli 91061|Bacilli L DNA polymerase III dnaQ - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T BJHFPPGC_00786 1046629.Ssal_00439 5.18e-76 232.0 2EHT6@1|root,33BIW@2|Bacteria,1VNC1@1239|Firmicutes,4HRJ5@91061|Bacilli 91061|Bacilli S Protein of unknown function, DUF536 WQ51_02910 - - - - - - - - - - - DUF536,HTH_11,HTH_24 BJHFPPGC_00787 1046629.Ssal_00437 1.17e-84 249.0 COG2151@1|root,COG2151@2|Bacteria,1VX9Z@1239|Firmicutes,4HXCM@91061|Bacilli 91061|Bacilli S cog cog2151 XK27_02560 - - - - - - - - - - - FeS_assembly_P BJHFPPGC_00788 904306.HMPREF9192_0774 0.0 1128.0 COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,4H9ZG@91061|Bacilli 91061|Bacilli E Belongs to the IlvD Edd family ilvD GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000 - - - ILVD_EDD BJHFPPGC_00789 1046629.Ssal_00435 8.1e-281 768.0 COG2081@1|root,COG2081@2|Bacteria,1TQ6E@1239|Firmicutes,4HAAT@91061|Bacilli 91061|Bacilli S Flavoprotein ytfP - - ko:K07007 - - - - ko00000 - - - HI0933_like BJHFPPGC_00791 1046629.Ssal_00434 2.07e-154 433.0 COG0220@1|root,COG0220@2|Bacteria,1TQCA@1239|Firmicutes,4HC08@91061|Bacilli 91061|Bacilli J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 ko:K03439 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_4 BJHFPPGC_00792 1046629.Ssal_00433 2.95e-197 545.0 COG0510@1|root,COG0510@2|Bacteria,1UMFY@1239|Firmicutes,4HBF9@91061|Bacilli 91061|Bacilli M Phosphotransferase ytmP - - - - - - - - - - - APH BJHFPPGC_00793 1046629.Ssal_00432 1.73e-222 616.0 COG4473@1|root,COG4473@2|Bacteria,1V9K7@1239|Firmicutes 1239|Firmicutes U Bacterial ABC transporter protein EcsB XK27_05910 - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - EcsB BJHFPPGC_00794 1046629.Ssal_00431 1.75e-170 476.0 COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,4HA2B@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein ecsA - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran BJHFPPGC_00795 904306.HMPREF9192_0767 7.19e-94 274.0 COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,4HIG2@91061|Bacilli 91061|Bacilli FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases hit - - ko:K02503 - - - - ko00000,ko04147 - - - HIT BJHFPPGC_00799 1046629.Ssal_00427 4e-133 378.0 2AIHW@1|root,318ZT@2|Bacteria,1V92M@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - DUF4230 BJHFPPGC_00801 1046629.Ssal_00425 0.0 1343.0 COG0542@1|root,COG0542@2|Bacteria,1TRHP@1239|Firmicutes,4HAHZ@91061|Bacilli 91061|Bacilli O ATP-dependent Clp protease ATP-binding subunit clpL - - ko:K04086 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,UVR BJHFPPGC_00802 1046629.Ssal_00423 3.49e-57 177.0 COG4115@1|root,COG4115@2|Bacteria,1VEN0@1239|Firmicutes,4HRVW@91061|Bacilli 91061|Bacilli S Addiction module toxin, Txe YoeB family yoeB - - ko:K19158 - - - - ko00000,ko01000,ko02048 - - - YoeB_toxin BJHFPPGC_00803 1046629.Ssal_00422 7.66e-52 163.0 COG2161@1|root,COG2161@2|Bacteria,1VM12@1239|Firmicutes,4HRMU@91061|Bacilli 91061|Bacilli D Antitoxin component of a toxin-antitoxin (TA) module yefM - - ko:K19159 - - - - ko00000,ko02048 - - - PhdYeFM_antitox BJHFPPGC_00804 435842.HMPREF0848_01254 9.67e-251 689.0 COG1323@1|root,COG1323@2|Bacteria,1TPP2@1239|Firmicutes,4HAZJ@91061|Bacilli 91061|Bacilli S Belongs to the UPF0348 family ylbM - - - - - - - - - - - HIGH_NTase1 BJHFPPGC_00805 1046629.Ssal_00420 3.04e-177 493.0 COG0500@1|root,COG2226@2|Bacteria,1V24K@1239|Firmicutes,4HDFY@91061|Bacilli 91061|Bacilli Q Methyltransferase domain protein XK27_06665 - - - - - - - - - - - Methyltransf_25 BJHFPPGC_00806 904306.HMPREF9192_0760 8.76e-75 224.0 COG0799@1|root,COG0799@2|Bacteria,1VA2Z@1239|Firmicutes,4HKEJ@91061|Bacilli 91061|Bacilli J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation rsfS GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 - ko:K09710 - - - - ko00000,ko03009 - - - RsfS BJHFPPGC_00807 435842.HMPREF0848_01257 2.01e-113 325.0 COG1335@1|root,COG1335@2|Bacteria,1VF7P@1239|Firmicutes,4HQSB@91061|Bacilli 91061|Bacilli Q Isochorismatase family yveA - - - - - - - - - - - Isochorismatase BJHFPPGC_00808 904306.HMPREF9192_0758 1.53e-137 389.0 COG1713@1|root,COG1713@2|Bacteria,1V6Y1@1239|Firmicutes,4HHRY@91061|Bacilli 91061|Bacilli H HD superfamily hydrolase involved in NAD metabolism yqeK - - - - - - - - - - - HD BJHFPPGC_00809 1046629.Ssal_00417 1.07e-150 423.0 COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,4HGXK@91061|Bacilli 91061|Bacilli H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) nadD GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 ko:K00969 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like BJHFPPGC_00810 1046629.Ssal_00416 4.57e-65 198.0 COG1534@1|root,COG1534@2|Bacteria,1VEGM@1239|Firmicutes,4HKC7@91061|Bacilli 91061|Bacilli J RNA-binding protein yhbY - - ko:K07574 - - - - ko00000,ko03009 - - - CRS1_YhbY BJHFPPGC_00811 1046629.Ssal_00415 3.11e-272 744.0 COG1161@1|root,COG1161@2|Bacteria,1TPM2@1239|Firmicutes,4HAAF@91061|Bacilli 91061|Bacilli S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis yqeH GO:0003674,GO:0003824,GO:0003924,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019219,GO:0019222,GO:0022613,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0042254,GO:0044085,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071840,GO:0080090,GO:0090329,GO:2000104,GO:2000112,GO:2000113 - ko:K06948 - - - - ko00000,ko03009 - - - MMR_HSR1 BJHFPPGC_00812 904306.HMPREF9192_0754 7.5e-127 360.0 COG2179@1|root,COG2179@2|Bacteria,1V6KM@1239|Firmicutes,4HGAV@91061|Bacilli 91061|Bacilli S hydrolase of the HAD superfamily yqeG - - ko:K07015 - - - - ko00000 - - - HAD_2,Hydrolase,Hydrolase_like,PGP_phosphatase BJHFPPGC_00813 904306.HMPREF9192_0753 1.4e-191 535.0 COG0697@1|root,COG0697@2|Bacteria,1TR6G@1239|Firmicutes,4HAMD@91061|Bacilli 91061|Bacilli EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA BJHFPPGC_00814 1114965.Spaf_1654 2.25e-241 664.0 COG1063@1|root,COG1063@2|Bacteria,1TPWP@1239|Firmicutes,4HABC@91061|Bacilli 91061|Bacilli E Dehydrogenase ydjL GO:0000721,GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0055114 1.1.1.264,1.1.1.303,1.1.1.4 ko:K00004,ko:K00098 ko00650,map00650 - R02855,R02946,R05684,R10504 RC00089,RC00205,RC00525 ko00000,ko00001,ko01000 - - iYO844.BSU06240 ADH_N,ADH_zinc_N BJHFPPGC_00815 435842.HMPREF0848_01264 7.46e-79 235.0 2B9ZC@1|root,323D0@2|Bacteria,1VBNR@1239|Firmicutes,4HNA3@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_00816 176090.SSIN_0689 7.07e-280 770.0 COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,4HDVN@91061|Bacilli 91061|Bacilli G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane celD - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - - PTS_EIIC BJHFPPGC_00817 171101.spr0281 6.84e-74 226.0 2E5MG@1|root,303YF@2|Bacteria,1TVHS@1239|Firmicutes,4I4RK@91061|Bacilli,1WUBA@1313|Streptococcus pneumoniae 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_00818 1054460.SPPN_09960 9.61e-53 167.0 COG1447@1|root,COG1447@2|Bacteria,1VAWR@1239|Firmicutes,4HM7W@91061|Bacilli 91061|Bacilli G Phosphotransferase system cellobiose-specific component IIA celC - 2.7.1.196,2.7.1.205 ko:K02759 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIA BJHFPPGC_00819 373153.SPD_0280 0.0 952.0 COG1762@1|root,COG3711@1|root,COG1762@2|Bacteria,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,4HEIQ@91061|Bacilli,1WUWZ@1313|Streptococcus pneumoniae 91061|Bacilli GKT Mga helix-turn-helix domain celR - - ko:K03491 - - - - ko00000,ko03000 - - - HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB BJHFPPGC_00820 862967.SIR_1124 4.78e-62 191.0 COG1440@1|root,COG1440@2|Bacteria,1VAE8@1239|Firmicutes,4HKQ2@91061|Bacilli,42ED8@671232|Streptococcus anginosus group 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit celB - 2.7.1.196,2.7.1.205 ko:K02760 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIB BJHFPPGC_00821 170187.SP_0304 4.27e-19 79.0 COG4095@1|root,COG4095@2|Bacteria,1VF4D@1239|Firmicutes,4I0UK@91061|Bacilli,1WVK7@1313|Streptococcus pneumoniae 91061|Bacilli S PQ loop repeat - - - ko:K15383 - - - - ko00000,ko02000 9.A.58.2 - - PQ-loop BJHFPPGC_00822 1054460.SPPN_09980 0.0 975.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family celA - 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 BJHFPPGC_00824 1046629.Ssal_00411 0.0 941.0 COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,4HAFB@91061|Bacilli 91061|Bacilli J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatB GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - GatB_N,GatB_Yqey BJHFPPGC_00825 904306.HMPREF9192_0732 0.0 925.0 COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,4HBAZ@91061|Bacilli 91061|Bacilli J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gatA - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase BJHFPPGC_00826 1046629.Ssal_00409 7.49e-64 195.0 COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,4HNNA@91061|Bacilli 91061|Bacilli J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatC - 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Glu-tRNAGln BJHFPPGC_00827 435842.HMPREF0848_01268 3.54e-292 805.0 COG0438@1|root,COG0438@2|Bacteria,1TR6K@1239|Firmicutes,4HGDG@91061|Bacilli 91061|Bacilli M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon gtf1 - - - - - - - - - - - Glycos_transf_1 BJHFPPGC_00828 435842.HMPREF0848_01269 5.72e-239 665.0 COG0438@1|root,COG0438@2|Bacteria,1TQZR@1239|Firmicutes 1239|Firmicutes M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1 - - - - - - - - - - - - - BJHFPPGC_00829 435842.HMPREF0848_01270 1.39e-201 559.0 COG1216@1|root,COG1216@2|Bacteria,1V7WV@1239|Firmicutes 1239|Firmicutes H COG0463 Glycosyltransferases involved in cell wall biogenesis - - - - - - - - - - - - Glycos_transf_2 BJHFPPGC_00830 435842.HMPREF0848_01271 4.3e-276 756.0 COG1442@1|root,COG1442@2|Bacteria 2|Bacteria M lipopolysaccharide 3-alpha-galactosyltransferase activity - - - - - - - - - - - - Glyco_transf_8 BJHFPPGC_00831 904306.HMPREF9192_0728 0.0 999.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family ascB - 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 BJHFPPGC_00832 322159.STER_1598 5.85e-128 363.0 COG1335@1|root,COG1335@2|Bacteria,1V1CY@1239|Firmicutes,4HFRS@91061|Bacilli 91061|Bacilli Q isochorismatase pncA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006208,GO:0006212,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0017144,GO:0019860,GO:0034641,GO:0042737,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 - ko:K16788 - - - - ko00000,ko02000 2.A.88.5 - - Isochorismatase BJHFPPGC_00833 1046629.Ssal_00404 2.12e-180 503.0 COG4465@1|root,COG4465@2|Bacteria,1TS7A@1239|Firmicutes,4HA9U@91061|Bacilli 91061|Bacilli K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor codY GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0044424,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K03706 - - - - ko00000,ko03000 - - - CodY,HTH_CodY BJHFPPGC_00834 1046629.Ssal_00403 4.15e-300 817.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HD83@91061|Bacilli 91061|Bacilli E Aminotransferase aspC - 2.6.1.2,2.6.1.66 ko:K14260 ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230 - R00258,R01215 RC00006,RC00008,RC00036 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 BJHFPPGC_00835 1046629.Ssal_00402 1.25e-97 284.0 COG0589@1|root,COG0589@2|Bacteria,1V3NY@1239|Firmicutes,4HIP3@91061|Bacilli 91061|Bacilli T universal stress protein XK27_03180 - - - - - - - - - - - Usp BJHFPPGC_00837 1046629.Ssal_00399 4.91e-202 558.0 COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,4HACV@91061|Bacilli 91061|Bacilli C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine pflA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.97.1.4 ko:K04069 - - R04710 - ko00000,ko01000 - - - Fer4_12,Radical_SAM BJHFPPGC_00839 1046629.Ssal_00397 5.53e-302 825.0 COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,4H9SB@91061|Bacilli 91061|Bacilli S COG1253 Hemolysins and related proteins containing CBS domains hlyX - - ko:K03699 - - - - ko00000,ko02042 - - - CBS,CorC_HlyC,DUF21 BJHFPPGC_00840 1046629.Ssal_00395 1.38e-180 503.0 COG1119@1|root,COG1119@2|Bacteria,1TRR4@1239|Firmicutes,4HB4U@91061|Bacilli 91061|Bacilli P abc transporter atp-binding protein ylmA - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran BJHFPPGC_00842 246201.SM12261_0265 7.29e-32 114.0 2BGH9@1|root,32AFE@2|Bacteria,1U4HU@1239|Firmicutes,4IE9N@91061|Bacilli,2TPX5@28037|Streptococcus mitis 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_00843 1046629.Ssal_00394 0.0 1256.0 COG0025@1|root,COG0025@2|Bacteria,1TR4G@1239|Firmicutes,4HBJR@91061|Bacilli 91061|Bacilli P NhaP-type Na H and K H antiporters nhaP1 - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger BJHFPPGC_00845 264199.stu1645 3.95e-121 346.0 COG0144@1|root,COG0144@2|Bacteria,1UHQD@1239|Firmicutes,4HIMC@91061|Bacilli 91061|Bacilli J (SAM)-dependent mraW1 - - - - - - - - - - - rRNA_methylase BJHFPPGC_00846 904306.HMPREF9192_0713 1.7e-233 641.0 COG1242@1|root,COG1242@2|Bacteria,1TQ57@1239|Firmicutes,4H9N8@91061|Bacilli 91061|Bacilli S radical SAM protein ytqA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K07139 - - - - ko00000 - - - Radical_SAM,Radical_SAM_C BJHFPPGC_00847 264199.stu1647 3.05e-240 662.0 COG3480@1|root,COG3480@2|Bacteria,1TRUF@1239|Firmicutes,4HBAY@91061|Bacilli 91061|Bacilli T Belongs to the peptidase S16 family lon - - ko:K07177 ko02024,map02024 - - - ko00000,ko00001,ko01002 - - - Lon_C,PDZ_2 BJHFPPGC_00848 1046629.Ssal_00388 3.77e-113 325.0 COG0669@1|root,COG0669@2|Bacteria,1V3MR@1239|Firmicutes,4HH47@91061|Bacilli 91061|Bacilli H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate coaD GO:0003674,GO:0003824,GO:0004595,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0070566,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like BJHFPPGC_00849 904306.HMPREF9192_0710 2.58e-120 344.0 COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,4HGXT@91061|Bacilli 91061|Bacilli L Methyltransferase rsmD - 2.1.1.171 ko:K08316 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Cons_hypoth95 BJHFPPGC_00850 32024.JMTI01000003_gene1689 9.28e-07 60.5 COG4928@1|root,COG4928@2|Bacteria,1RBWH@1224|Proteobacteria,43BDT@68525|delta/epsilon subdivisions,2YQ3A@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria S KAP family P-loop domain - - - - - - - - - - - - KAP_NTPase BJHFPPGC_00851 1046629.Ssal_00386 1.13e-218 603.0 COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,4HA4N@91061|Bacilli 91061|Bacilli C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family trxB - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2 BJHFPPGC_00852 40041.SZO_03890 3.64e-14 67.8 29I01@1|root,304X3@2|Bacteria,1TXCH@1239|Firmicutes,4I6AC@91061|Bacilli,1M9T3@119603|Streptococcus dysgalactiae group 91061|Bacilli S Protein of unknown function (DUF4059) - - - - - - - - - - - - DUF4059 BJHFPPGC_00853 1046629.Ssal_00383 2.55e-165 463.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli 91061|Bacilli E abc transporter atp-binding protein tcyN - 3.6.3.21 ko:K02028,ko:K10010,ko:K16960 ko02010,map02010 M00234,M00236,M00585 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3,3.A.1.3.10,3.A.1.3.13,3.A.1.3.14 - - ABC_tran BJHFPPGC_00854 264199.stu1653 7.74e-203 564.0 COG0765@1|root,COG0765@2|Bacteria,1UZ2C@1239|Firmicutes,4HF77@91061|Bacilli 91061|Bacilli P ABC transporter (Permease yxeN - - ko:K02029,ko:K16959,ko:K16962 ko02010,map02010 M00236,M00585,M00586 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.13 - - BPD_transp_1 BJHFPPGC_00855 1046629.Ssal_00380 2.71e-195 541.0 COG0834@1|root,COG0834@2|Bacteria,1V7WQ@1239|Firmicutes,4HK1Z@91061|Bacilli 91061|Bacilli ET ABC-type amino acid transport signal transduction systems, periplasmic component domain - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 BJHFPPGC_00857 435842.HMPREF0848_01305 1.51e-258 709.0 COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4HADJ@91061|Bacilli 91061|Bacilli L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH BJHFPPGC_00858 1046629.Ssal_00375 0.0 1561.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,4H9RD@91061|Bacilli 91061|Bacilli C formate acetyltransferase' pflB - 2.3.1.54 ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 - R00212,R06987 RC00004,RC01181,RC02742,RC02833 ko00000,ko00001,ko01000 - - - Gly_radical,PFL-like BJHFPPGC_00859 1046629.Ssal_00372 2.91e-182 507.0 COG3338@1|root,COG3338@2|Bacteria,1V16J@1239|Firmicutes,4HA62@91061|Bacilli 91061|Bacilli P carbonic anhydrase cah - 4.2.1.1 ko:K01674 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Carb_anhydrase BJHFPPGC_00860 322159.STER_1624 7.13e-95 278.0 COG2153@1|root,COG2153@2|Bacteria,1VA2J@1239|Firmicutes,4HKF5@91061|Bacilli 91061|Bacilli S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases yjcF GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747 - - - - - - - - - - Acetyltransf_10 BJHFPPGC_00862 1046629.Ssal_00368 1.94e-219 606.0 COG1680@1|root,COG1680@2|Bacteria,1TNZX@1239|Firmicutes,4IPJT@91061|Bacilli 91061|Bacilli V COG1680 Beta-lactamase class C and other penicillin binding proteins - - - - - - - - - - - - Beta-lactamase BJHFPPGC_00863 1046629.Ssal_00367 9.6e-173 483.0 COG0346@1|root,COG0346@2|Bacteria,1VMPM@1239|Firmicutes,4HSVM@91061|Bacilli 91061|Bacilli E CppA N-terminal cppA - - - - - - - - - - - CppA_C,CppA_N BJHFPPGC_00864 1046629.Ssal_00366 2.66e-122 351.0 COG1266@1|root,COG1266@2|Bacteria 2|Bacteria V CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi BJHFPPGC_00865 264199.stu1671 8.98e-193 536.0 COG0580@1|root,COG0580@2|Bacteria,1TP4T@1239|Firmicutes,4HE39@91061|Bacilli 91061|Bacilli U Belongs to the MIP aquaporin (TC 1.A.8) family gla - - ko:K02440 - - - - ko00000,ko02000 1.A.8.1,1.A.8.2 - - MIP BJHFPPGC_00866 1046629.Ssal_00364 0.0 1465.0 COG2936@1|root,COG2936@2|Bacteria,1TT78@1239|Firmicutes,4HBA0@91061|Bacilli 91061|Bacilli E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline pepX - 3.4.14.11 ko:K01281 - - - - ko00000,ko01000,ko01002 - - - PepX_C,PepX_N,Peptidase_S15 BJHFPPGC_00867 322159.STER_1636 3.48e-57 178.0 COG1476@1|root,COG1476@2|Bacteria 2|Bacteria K sequence-specific DNA binding spiA - - ko:K18831 - - - - ko00000,ko02048,ko03000 - - - EntA_Immun,HTH_3,Peptidase_M78,Peptidase_S24 BJHFPPGC_00872 435842.HMPREF0848_01339 0.0 1076.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein mdlB - - ko:K06147,ko:K18890 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran BJHFPPGC_00873 1046629.Ssal_00350 0.0 1097.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein mdlA - - ko:K06148,ko:K18889 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.106.13,3.A.1.106.5 - - ABC_membrane,ABC_tran BJHFPPGC_00876 1046629.Ssal_00348 3.55e-116 333.0 COG4767@1|root,COG4767@2|Bacteria,1VKIA@1239|Firmicutes,4HQZW@91061|Bacilli 91061|Bacilli V Glycopeptide antibiotics resistance protein XK27_09885 - - - - - - - - - - - VanZ BJHFPPGC_00877 1046629.Ssal_00347 8.09e-283 772.0 COG0820@1|root,COG0820@2|Bacteria,1TPVF@1239|Firmicutes,4H9NU@91061|Bacilli 91061|Bacilli J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs rlmN GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 ko:K06941 - - - - ko00000,ko01000,ko03009 - - - Fer4_14,Radical_SAM BJHFPPGC_00878 264199.stu1697 2.27e-107 316.0 COG4470@1|root,COG4470@2|Bacteria,1VA85@1239|Firmicutes,4HKF7@91061|Bacilli 91061|Bacilli J protein conserved in bacteria yutD - - - - - - - - - - - DUF1027 BJHFPPGC_00879 1046629.Ssal_00344 0.0 890.0 COG0737@1|root,COG0737@2|Bacteria,1TQCW@1239|Firmicutes,4HAUC@91061|Bacilli 91061|Bacilli F Belongs to the 5'-nucleotidase family yunD - 3.1.3.5 ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Metallophos BJHFPPGC_00880 585204.SMSK597_1867 1.05e-59 184.0 COG2963@1|root,COG2963@2|Bacteria,1U4Y6@1239|Firmicutes,4IEPQ@91061|Bacilli,2TQEJ@28037|Streptococcus mitis 91061|Bacilli L transposase activity - - - - - - - - - - - - - BJHFPPGC_00881 585204.SMSK597_1866 3.85e-194 538.0 COG2801@1|root,COG2801@2|Bacteria,1UVZW@1239|Firmicutes,4I47Y@91061|Bacilli,2TQDQ@28037|Streptococcus mitis 91061|Bacilli L Integrase core domain - - - - - - - - - - - - rve BJHFPPGC_00883 1046629.Ssal_00342 3.25e-301 825.0 COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HA98@91061|Bacilli 91061|Bacilli JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures cshB GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592,ko:K18692 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,Helicase_C BJHFPPGC_00884 1046629.Ssal_00341 8.08e-236 649.0 COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,4H9TP@91061|Bacilli 91061|Bacilli M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan mraY - 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 - R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 - - Glycos_transf_4,MraY_sig1 BJHFPPGC_00885 904306.HMPREF9192_0666 0.0 1396.0 COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,4H9VQ@91061|Bacilli 91061|Bacilli M penicillin-binding protein pbpX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PASTA,PBP_dimer,Transpeptidase BJHFPPGC_00886 435842.HMPREF0848_01354 5.32e-60 186.0 COG4839@1|root,COG4839@2|Bacteria,1VCE5@1239|Firmicutes,4HM4W@91061|Bacilli 91061|Bacilli D cell division protein FtsL ftsL - - - - - - - - - - - DivIC BJHFPPGC_00887 322159.STER_1668 2.67e-222 613.0 COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,4H9U2@91061|Bacilli 91061|Bacilli J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 BJHFPPGC_00888 264199.stu1704 4.18e-134 392.0 2DDKD@1|root,2ZIF1@2|Bacteria,1W5UA@1239|Firmicutes,4HZND@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_00891 1046629.Ssal_00333 4.25e-60 188.0 COG3152@1|root,COG3152@2|Bacteria,1V90R@1239|Firmicutes,4HQ7Q@91061|Bacilli 91061|Bacilli J Protein of unknown function (DUF805) - - - - - - - - - - - - DUF805 BJHFPPGC_00892 1046629.Ssal_00333 1.6e-89 262.0 COG3152@1|root,COG3152@2|Bacteria,1V90R@1239|Firmicutes,4HQ7Q@91061|Bacilli 91061|Bacilli J Protein of unknown function (DUF805) - - - - - - - - - - - - DUF805 BJHFPPGC_00893 435842.HMPREF0848_01358 1.26e-39 136.0 COG3152@1|root,COG3152@2|Bacteria,1V90R@1239|Firmicutes,4HQ7Q@91061|Bacilli 91061|Bacilli J Protein of unknown function (DUF805) - - - - - - - - - - - - DUF805 BJHFPPGC_00894 435842.HMPREF0848_01359 7.98e-80 238.0 COG3152@1|root,COG3152@2|Bacteria,1V90R@1239|Firmicutes 1239|Firmicutes J Membrane - - - - - - - - - - - - DUF805,zinc_ribbon_2 BJHFPPGC_00895 904306.HMPREF9192_0660 6.47e-285 780.0 COG0014@1|root,COG0014@2|Bacteria,1TQ9V@1239|Firmicutes,4HB7B@91061|Bacilli 91061|Bacilli E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate proA GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU13130 Aldedh BJHFPPGC_00896 904306.HMPREF9192_0659 1.43e-181 506.0 COG0263@1|root,COG0263@2|Bacteria,1TPG6@1239|Firmicutes,4HA9B@91061|Bacilli 91061|Bacilli E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate proB GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase BJHFPPGC_00897 1046629.Ssal_01083 0.0 1206.0 COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,4H9VJ@91061|Bacilli 91061|Bacilli F Belongs to the 5'-nucleotidase family sasH - 3.1.3.5 ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Gram_pos_anchor,Metallophos BJHFPPGC_00898 699248.SRA_05851 2.19e-103 304.0 COG0765@1|root,COG0765@2|Bacteria,1TQ43@1239|Firmicutes,4HCZV@91061|Bacilli 91061|Bacilli P ABC transporter (Permease yckA GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - ko:K10009 ko02010,map02010 M00234 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.10,3.A.1.3.14 - - BPD_transp_1 BJHFPPGC_00899 435842.HMPREF0848_00690 7.99e-191 531.0 COG0834@1|root,COG0834@2|Bacteria,1UHHG@1239|Firmicutes,4H9NX@91061|Bacilli 91061|Bacilli ET Belongs to the bacterial solute-binding protein 3 family yckB - - ko:K02030,ko:K02424 ko02010,map02010 M00234,M00236 - - ko00000,ko00001,ko00002,ko02000,ko02035 3.A.1.3,3.A.1.3.10,3.A.1.3.14 - - SBP_bac_3 BJHFPPGC_00900 435842.HMPREF0848_00691 6.7e-305 836.0 COG0154@1|root,COG0154@2|Bacteria,1TPGJ@1239|Firmicutes,4HBE7@91061|Bacilli 91061|Bacilli J Belongs to the amidase family nylA - 3.5.1.4 ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 - R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000 - - - Amidase BJHFPPGC_00901 1046629.Ssal_01081 3.05e-145 409.0 COG0461@1|root,COG0461@2|Bacteria,1V1BZ@1239|Firmicutes,4HFV7@91061|Bacilli 91061|Bacilli F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) pyrE - 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15560 Pribosyltran BJHFPPGC_00902 435842.HMPREF0848_00693 1.55e-158 445.0 COG0284@1|root,COG0284@2|Bacteria,1TPPH@1239|Firmicutes,4HAJ2@91061|Bacilli 91061|Bacilli F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) pyrF GO:0003674,GO:0003824,GO:0004590,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase BJHFPPGC_00903 889204.HMPREF9423_0556 1.05e-157 457.0 28K2E@1|root,2Z9RR@2|Bacteria,1TRJ6@1239|Firmicutes 1239|Firmicutes S Psort location Cytoplasmic, score - - - - - - - - - - - - Cas_Csm6 BJHFPPGC_00904 889204.HMPREF9423_0555 1.6e-158 457.0 28K2E@1|root,2Z9RR@2|Bacteria,1TRJ6@1239|Firmicutes 1239|Firmicutes S Psort location Cytoplasmic, score - - - - - - - - - - - - Cas_Csm6 BJHFPPGC_00905 322159.STER_0977 8.38e-258 706.0 COG1332@1|root,COG1332@2|Bacteria,1V8JA@1239|Firmicutes 1239|Firmicutes L CRISPR-associated RAMP protein, Csm5 family csm5 - - ko:K19140 - - - - ko00000,ko02048 - - - RAMPs BJHFPPGC_00906 264199.stu0963 1.77e-207 574.0 COG1567@1|root,COG1567@2|Bacteria,1V4UZ@1239|Firmicutes 1239|Firmicutes L CRISPR-associated RAMP protein, Csm4 family csm4 - - ko:K19139 - - - - ko00000,ko02048 - - - RAMPs BJHFPPGC_00907 322159.STER_0975 2.12e-146 413.0 COG1337@1|root,COG1337@2|Bacteria,1V3DM@1239|Firmicutes,4HPB8@91061|Bacilli 91061|Bacilli L RAMP superfamily csm3 - - ko:K09002 - - - - ko00000,ko02048 - - - RAMPs BJHFPPGC_00908 264199.stu0961 1.99e-78 234.0 COG1421@1|root,COG1421@2|Bacteria,1VGBY@1239|Firmicutes,4HYAX@91061|Bacilli 91061|Bacilli L Pfam:DUF310 - - - ko:K19138 - - - - ko00000,ko02048 - - - Csm2_III-A BJHFPPGC_00909 264199.stu0960 0.0 1445.0 COG1353@1|root,COG1353@2|Bacteria,1TRW5@1239|Firmicutes,4HM8F@91061|Bacilli 91061|Bacilli S CRISPR-associated protein Csm1 family csm1 - - ko:K07016 - - - - ko00000,ko02048 - - - HD BJHFPPGC_00910 264199.stu0959 5.01e-170 475.0 COG5551@1|root,COG5551@2|Bacteria,1V7VJ@1239|Firmicutes,4HZ1B@91061|Bacilli 91061|Bacilli S Pfam:DUF2276 - - - - - - - - - - - - CRISPR_Cas6 BJHFPPGC_00911 264199.stu0958 4.84e-71 214.0 COG1343@1|root,COG1343@2|Bacteria,1VFRC@1239|Firmicutes 1239|Firmicutes L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette cas2 - - ko:K09951 - - - - ko00000,ko02048 - - - CRISPR_Cas2 BJHFPPGC_00912 322159.STER_0970 6.34e-230 634.0 COG1518@1|root,COG1518@2|Bacteria,1TQWG@1239|Firmicutes 1239|Firmicutes L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette cas1 - - ko:K15342 - - - - ko00000,ko02048,ko03400 - - - Cas_Cas1 BJHFPPGC_00913 435842.HMPREF0848_00694 2.29e-224 619.0 COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,4HA5H@91061|Bacilli 91061|Bacilli F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily pyrD GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.98.1 ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01867,R01869 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh BJHFPPGC_00914 435842.HMPREF0848_00695 1.62e-187 521.0 COG0543@1|root,COG0543@2|Bacteria,1TQ5D@1239|Firmicutes,4HAU4@91061|Bacilli 91061|Bacilli C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) pyrK GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042602,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0052875,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - ko:K02823 ko00240,ko01100,map00240,map01100 - - - ko00000,ko00001 - - iYO844.BSU15530 DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1 BJHFPPGC_00915 904306.HMPREF9192_1766 5.38e-119 341.0 COG0693@1|root,COG0693@2|Bacteria,1V3WB@1239|Firmicutes,4HM36@91061|Bacilli 91061|Bacilli S DJ-1 family thiJ - 3.5.1.124 ko:K03152 - - - - ko00000,ko01000,ko01002 - - - DJ-1_PfpI BJHFPPGC_00916 904306.HMPREF9192_1767 6.45e-173 484.0 2B4EH@1|root,31X62@2|Bacteria,1V7WE@1239|Firmicutes,4HJ8G@91061|Bacilli 91061|Bacilli S TraX protein - - - - - - - - - - - - TraX BJHFPPGC_00917 1046629.Ssal_01074 0.0 1058.0 COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,4H9UF@91061|Bacilli 91061|Bacilli K RNA-binding protein homologous to eukaryotic snRNP FbpA - - - - - - - - - - - DUF814,FbpA BJHFPPGC_00918 435842.HMPREF0848_00699 0.0 1431.0 COG4086@1|root,COG4086@2|Bacteria,1TR2I@1239|Firmicutes,4HBVZ@91061|Bacilli 91061|Bacilli S secreted protein - - - - - - - - - - - - DUF1002 BJHFPPGC_00919 435842.HMPREF0848_00700 0.0 1028.0 COG3152@1|root,COG3152@2|Bacteria 2|Bacteria L Membrane yhaI - - - - - - - - - - - DUF805 BJHFPPGC_00923 435842.HMPREF0848_00704 2.89e-221 610.0 COG1396@1|root,COG1396@2|Bacteria,1V957@1239|Firmicutes,4HJXP@91061|Bacilli 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - - BJHFPPGC_00924 1046629.Ssal_01073 0.0 982.0 2DM53@1|root,31R8Y@2|Bacteria,1UK4X@1239|Firmicutes,4IU8I@91061|Bacilli 91061|Bacilli S Psort location CytoplasmicMembrane, score - - - - - - - - - - - - - BJHFPPGC_00925 1046629.Ssal_01071 7.46e-297 813.0 COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,4HANM@91061|Bacilli 91061|Bacilli V Mate efflux family protein dinF - - - - - - - - - - - MatE BJHFPPGC_00926 1046629.Ssal_01070 1.48e-222 614.0 COG4607@1|root,COG4607@2|Bacteria,1UXCZ@1239|Firmicutes,4HAMP@91061|Bacilli 91061|Bacilli P ABC-type enterochelin transport system, periplasmic component - - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 BJHFPPGC_00927 435842.HMPREF0848_00708 0.0 1424.0 COG1061@1|root,COG1061@2|Bacteria,1TRA8@1239|Firmicutes,4HCIF@91061|Bacilli 91061|Bacilli V Type III restriction enzyme, res subunit - - - - - - - - - - - - Helicase_C,ResIII BJHFPPGC_00928 322159.STER_0956 3.41e-143 404.0 COG0546@1|root,COG0546@2|Bacteria,1TPPZ@1239|Firmicutes,4IPIP@91061|Bacilli 91061|Bacilli S HAD hydrolase, family IA, variant 1 - - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 BJHFPPGC_00929 888833.HMPREF9421_1644 1.42e-170 477.0 COG2820@1|root,COG2820@2|Bacteria,1TQ71@1239|Firmicutes,4HUI7@91061|Bacilli 91061|Bacilli F Phosphorylase superfamily - - - - - - - - - - - - PNP_UDP_1 BJHFPPGC_00932 1114965.Spaf_1743 5.39e-175 491.0 COG4814@1|root,COG4814@2|Bacteria,1V01B@1239|Firmicutes 1239|Firmicutes G protein with an alpha beta hydrolase fold - - - - - - - - - - - - DUF915 BJHFPPGC_00933 904306.HMPREF9192_1783 3.72e-239 658.0 COG1063@1|root,COG1063@2|Bacteria,1TPIW@1239|Firmicutes,4HB2G@91061|Bacilli 91061|Bacilli E Dehydrogenase adhB - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N BJHFPPGC_00934 999425.HMPREF9186_00908 8.22e-248 682.0 COG0276@1|root,COG0276@2|Bacteria,1TPKF@1239|Firmicutes,4HAYG@91061|Bacilli 91061|Bacilli H Catalyzes the ferrous insertion into protoporphyrin IX hemH GO:0003674,GO:0003824,GO:0004325,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 - - - Ferrochelatase BJHFPPGC_00935 264199.stu0932 2.45e-193 538.0 COG1230@1|root,COG1230@2|Bacteria,1TR92@1239|Firmicutes,4HBCQ@91061|Bacilli 91061|Bacilli P cation diffusion facilitator family transporter czcD - - ko:K16264 - - - - ko00000,ko02000 2.A.4.1 - - Cation_efflux BJHFPPGC_00936 1316408.HSISM1_2037 1.1e-121 347.0 COG1309@1|root,COG1309@2|Bacteria,1TSUJ@1239|Firmicutes,4IPZN@91061|Bacilli 91061|Bacilli K Transcriptional regulator, TetR family - - - - - - - - - - - - TetR_C_8,TetR_N BJHFPPGC_00937 888048.HMPREF8577_1220 7.98e-76 230.0 2BS9S@1|root,32XMN@2|Bacteria,1VA8B@1239|Firmicutes 1239|Firmicutes S Protein of unknown function with HXXEE motif - - - - - - - - - - - - HXXEE BJHFPPGC_00938 999425.HMPREF9186_00912 7.85e-48 155.0 2DD3F@1|root,2ZGBB@2|Bacteria,1W4NX@1239|Firmicutes,4I0KR@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_00939 999425.HMPREF9186_00913 1.04e-192 536.0 COG1028@1|root,COG1028@2|Bacteria,1TRQB@1239|Firmicutes,4HAY3@91061|Bacilli 91061|Bacilli IQ Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short BJHFPPGC_00940 889204.HMPREF9423_1742 2.61e-193 537.0 COG2267@1|root,COG2267@2|Bacteria,1UWGW@1239|Firmicutes,4IDYE@91061|Bacilli,43GIA@68892|Streptococcus infantis 91061|Bacilli I Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1 BJHFPPGC_00941 999425.HMPREF9186_00915 6.78e-225 621.0 COG0604@1|root,COG0604@2|Bacteria,1TQ0M@1239|Firmicutes,4HA8M@91061|Bacilli 91061|Bacilli C nadph quinone reductase - - - - - - - - - - - - ADH_N,ADH_zinc_N_2 BJHFPPGC_00942 889204.HMPREF9423_1744 3.77e-86 254.0 COG1959@1|root,COG1959@2|Bacteria,1V53C@1239|Firmicutes,4HN6G@91061|Bacilli 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - Rrf2 BJHFPPGC_00943 999425.HMPREF9186_00918 1.56e-78 239.0 COG3201@1|root,COG3201@2|Bacteria,1UYDN@1239|Firmicutes,4HJE5@91061|Bacilli 91061|Bacilli H nicotinamide mononucleotide transporter pnuC - - ko:K03811 - - - - ko00000,ko02000 4.B.1.1 - - NMN_transporter BJHFPPGC_00944 435842.HMPREF0848_00734 2.82e-192 533.0 COG1122@1|root,COG1122@2|Bacteria,1VSUE@1239|Firmicutes,4HT6W@91061|Bacilli 91061|Bacilli P ABC transporter, ATP-binding protein - - - ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran BJHFPPGC_00945 435842.HMPREF0848_00735 4.67e-200 554.0 COG1122@1|root,COG1122@2|Bacteria 2|Bacteria P ATPase activity - - - ko:K16786,ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran BJHFPPGC_00946 888048.HMPREF8577_1226 3.58e-169 474.0 COG0619@1|root,COG0619@2|Bacteria,1UYQQ@1239|Firmicutes,4HFDP@91061|Bacilli 91061|Bacilli P cobalt transport - - - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - CbiQ BJHFPPGC_00947 1316408.HSISM1_2045 1.44e-125 359.0 COG3275@1|root,COG3275@2|Bacteria,1V65C@1239|Firmicutes 1239|Firmicutes T Psort location CytoplasmicMembrane, score - - - ko:K16923 - M00582 - - ko00000,ko00002,ko02000 3.A.1.28 - - ECF_trnsprt,Reg_prop,Y_Y_Y BJHFPPGC_00948 904306.HMPREF9192_1795 7.03e-177 494.0 COG0384@1|root,COG0384@2|Bacteria,1TPPX@1239|Firmicutes,4HDAC@91061|Bacilli 91061|Bacilli S Phenazine biosynthesis protein - - - - - - - - - - - - PhzC-PhzF BJHFPPGC_00949 888833.HMPREF9421_1655 0.0 917.0 COG1174@1|root,COG1732@1|root,COG1174@2|Bacteria,COG1732@2|Bacteria,1TQ7D@1239|Firmicutes,4HBDR@91061|Bacilli 91061|Bacilli P ABC transporter proWX - - ko:K05845,ko:K05846 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1,OpuAC BJHFPPGC_00950 888833.HMPREF9421_1656 4.71e-162 455.0 COG1125@1|root,COG1125@2|Bacteria,1TPV8@1239|Firmicutes,4H9SI@91061|Bacilli 91061|Bacilli E abc transporter atp-binding protein proV - - ko:K05847 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - ABC_tran BJHFPPGC_00951 435842.HMPREF0848_00741 6.53e-191 534.0 COG0604@1|root,COG0604@2|Bacteria,1V55H@1239|Firmicutes,4HD0S@91061|Bacilli 91061|Bacilli C alcohol dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2 BJHFPPGC_00952 904306.HMPREF9192_1799 3.16e-86 255.0 COG1846@1|root,COG1846@2|Bacteria,1VDJQ@1239|Firmicutes,4HN0M@91061|Bacilli 91061|Bacilli K Transcriptional regulator, MarR family - - - - - - - - - - - - MarR BJHFPPGC_00953 322159.STER_0941 7.74e-172 479.0 COG3527@1|root,COG3527@2|Bacteria,1V4AH@1239|Firmicutes,4HJ98@91061|Bacilli 91061|Bacilli H Belongs to the alpha-acetolactate decarboxylase family budA - 4.1.1.5 ko:K01575 ko00650,ko00660,map00650,map00660 - R02948 RC00812 ko00000,ko00001,ko01000 - - - AAL_decarboxy BJHFPPGC_00954 1046629.Ssal_01037 0.0 1085.0 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4HAV1@91061|Bacilli 91061|Bacilli EH Belongs to the TPP enzyme family alsS - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N BJHFPPGC_00957 1046629.Ssal_01034 0.0 1178.0 COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,4HASA@91061|Bacilli 91061|Bacilli M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C BJHFPPGC_00959 435842.HMPREF0848_00749 2.2e-174 487.0 COG1028@1|root,COG1028@2|Bacteria,1TRQC@1239|Firmicutes,4HD7P@91061|Bacilli 91061|Bacilli IQ Acetoin reductase butA - 1.1.1.304,1.1.1.76 ko:K03366 ko00650,map00650 - R02855,R02946,R03707,R09078,R10505 RC00205,RC00525 ko00000,ko00001,ko01000 - - - adh_short,adh_short_C2 BJHFPPGC_00960 904306.HMPREF9192_1808 7.63e-58 179.0 COG0607@1|root,COG0607@2|Bacteria,1U0PW@1239|Firmicutes 1239|Firmicutes P Rhodanese-like protein - - - - - - - - - - - - Rhodanese BJHFPPGC_00961 264199.stu0906 1.48e-93 273.0 COG0105@1|root,COG0105@2|Bacteria,1V44G@1239|Firmicutes 1239|Firmicutes F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate ndk GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 - - - NDK BJHFPPGC_00962 1046629.Ssal_01022 1.24e-281 769.0 COG0620@1|root,COG0620@2|Bacteria,1TPDQ@1239|Firmicutes,4HADW@91061|Bacilli 91061|Bacilli E Methionine synthase XK27_05470 - - - - - - - - - - - Meth_synt_2 BJHFPPGC_00963 1046629.Ssal_01021 0.0 882.0 COG1206@1|root,COG1206@2|Bacteria,1TP67@1239|Firmicutes,4HB27@91061|Bacilli 91061|Bacilli J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs trmFO GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 ko:K04094 - - - - ko00000,ko01000,ko03016,ko03036 - - - GIDA BJHFPPGC_00964 435842.HMPREF0848_00753 6.1e-299 819.0 COG0642@1|root,COG2205@2|Bacteria,1TS1G@1239|Firmicutes,4HEC4@91061|Bacilli 91061|Bacilli T ATPase histidine kinase DNA gyrase B HSP90 domain protein spaK - 2.7.13.3 ko:K20487 ko02020,ko02024,map02020,map02024 M00816 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA BJHFPPGC_00965 904306.HMPREF9192_1813 9.43e-154 432.0 COG0745@1|root,COG0745@2|Bacteria,1TQ0D@1239|Firmicutes,4HDA9@91061|Bacilli 91061|Bacilli KT Transcriptional regulatory protein, C terminal spaR - - ko:K20488 ko02020,ko02024,map02020,map02024 M00816 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C BJHFPPGC_00966 435842.HMPREF0848_00755 3.29e-195 541.0 2DC01@1|root,2ZC51@2|Bacteria,1V2FW@1239|Firmicutes,4HG69@91061|Bacilli 91061|Bacilli S TraX protein - - - - - - - - - - - - TraX BJHFPPGC_00967 1046629.Ssal_01017 0.0 1359.0 COG0550@1|root,COG0550@2|Bacteria,1TPUS@1239|Firmicutes,4HA6C@91061|Bacilli 91061|Bacilli L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topoisom_bac,Toprim,zf-C4_Topoisom BJHFPPGC_00968 435842.HMPREF0848_00757 1.24e-197 548.0 COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,4HGWM@91061|Bacilli 91061|Bacilli LU DNA protecting protein DprA dprA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0044424,GO:0044464,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - ko:K04096 - - - - ko00000 - - - DNA_processg_A BJHFPPGC_00969 435842.HMPREF0848_00758 1.33e-201 560.0 COG1940@1|root,COG1940@2|Bacteria,1TRQ7@1239|Firmicutes 1239|Firmicutes GK ROK family - - - - - - - - - - - - ROK BJHFPPGC_00970 435842.HMPREF0848_00759 4.05e-174 486.0 COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,4HB7M@91061|Bacilli 91061|Bacilli L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII BJHFPPGC_00971 435842.HMPREF0848_00760 1.15e-200 556.0 COG1161@1|root,COG1161@2|Bacteria,1TQGK@1239|Firmicutes,4HA4D@91061|Bacilli 91061|Bacilli S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity rbgA GO:0003674,GO:0003824,GO:0003924,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022613,GO:0042254,GO:0044085,GO:0071840 - ko:K14540 - - - - ko00000,ko03009 - - - MMR_HSR1 BJHFPPGC_00972 435842.HMPREF0848_00761 3.17e-166 464.0 COG1396@1|root,COG2932@1|root,COG1396@2|Bacteria,COG2932@2|Bacteria,1V758@1239|Firmicutes,4HIKZ@91061|Bacilli 91061|Bacilli K DNA-binding helix-turn-helix protein - - - - - - - - - - - - HTH_19,HTH_3,Peptidase_S24 BJHFPPGC_00973 435842.HMPREF0848_00762 1.92e-118 338.0 COG1827@1|root,COG1827@2|Bacteria,1V6EY@1239|Firmicutes,4HGYB@91061|Bacilli 91061|Bacilli S small molecule binding protein (contains 3H domain) yrxA - - ko:K07105 - - - - ko00000 - - - 3H,HTH_11 BJHFPPGC_00974 435842.HMPREF0848_00763 1.33e-111 322.0 2A1RE@1|root,32VI2@2|Bacteria,1VDRR@1239|Firmicutes 1239|Firmicutes - - - - - ko:K16788 - - - - ko00000,ko02000 2.A.88.5 - - ECF-ribofla_trS BJHFPPGC_00975 1046629.Ssal_01006 0.0 956.0 COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,4H9T4@91061|Bacilli 91061|Bacilli U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY ffh - 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB BJHFPPGC_00976 435842.HMPREF0848_00765 5.56e-72 216.0 COG2739@1|root,COG2739@2|Bacteria,1VEGP@1239|Firmicutes,4HKK6@91061|Bacilli 91061|Bacilli S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein ylxM GO:0003674,GO:0008150,GO:0030234,GO:0030695,GO:0050790,GO:0060589,GO:0065007,GO:0065009,GO:0098772 - ko:K09787 - - - - ko00000 - - - UPF0122 BJHFPPGC_00977 435842.HMPREF0848_00766 3.02e-161 452.0 COG2188@1|root,COG2188@2|Bacteria,1UYBW@1239|Firmicutes,4HDDG@91061|Bacilli 91061|Bacilli K transcriptional yvoA_2 - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA BJHFPPGC_00978 435842.HMPREF0848_00767 0.0 1039.0 COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,4HA7Q@91061|Bacilli 91061|Bacilli F Catalyzes the synthesis of GMP from XMP guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase,GMP_synt_C,NAD_synthase BJHFPPGC_00979 1035189.HMPREF9954_1729 9.14e-107 317.0 2EDPB@1|root,337J0@2|Bacteria,1VV0W@1239|Firmicutes,4HVVE@91061|Bacilli,43GDQ@68892|Streptococcus infantis 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_00980 1095738.HMPREF1047_1139 9.44e-177 550.0 29YAF@1|root,30K4J@2|Bacteria,1UN93@1239|Firmicutes,4IU86@91061|Bacilli,1WQ05@1303|Streptococcus oralis 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_00982 1211819.CALK01000014_gene455 2.9e-28 127.0 COG1474@1|root,COG3410@1|root,COG1474@2|Bacteria,COG3410@2|Bacteria,1TPQU@1239|Firmicutes,3VPDQ@526524|Erysipelotrichia 526524|Erysipelotrichia L Uncharacterized conserved protein (DUF2075) - - - - - - - - - - - - DUF2075 BJHFPPGC_00983 1139996.OMQ_01163 8.58e-61 209.0 COG3183@1|root,COG3440@1|root,COG3183@2|Bacteria,COG3440@2|Bacteria,1V6W0@1239|Firmicutes,4HJKE@91061|Bacilli 91061|Bacilli V An automated process has identified a potential problem with this gene model - - - - - - - - - - - - DUF3578,DUF3883 BJHFPPGC_00984 562981.HMPREF0428_00622 9.14e-51 163.0 COG1694@1|root,COG1694@2|Bacteria,1VA3E@1239|Firmicutes,4HKDQ@91061|Bacilli,3WF2Z@539002|Bacillales incertae sedis 91061|Bacilli S MazG-like family - - - - - - - - - - - - MazG-like BJHFPPGC_00985 1347369.CCAD010000077_gene2883 2.28e-278 776.0 COG3410@1|root,COG3410@2|Bacteria,1TPQU@1239|Firmicutes,4HBI0@91061|Bacilli,1ZB68@1386|Bacillus 91061|Bacilli L Uncharacterized conserved protein (DUF2075) - - - ko:K09384 - - - - ko00000 - - - DUF2075,GIY-YIG BJHFPPGC_00988 1095738.HMPREF1047_1591 3.11e-58 181.0 29QR3@1|root,30BQX@2|Bacteria,1TWYS@1239|Firmicutes,4I5TQ@91061|Bacilli,1WPXV@1303|Streptococcus oralis 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_00989 699248.SRA_07791 3.39e-253 695.0 COG1674@1|root,COG1674@2|Bacteria,1UZV0@1239|Firmicutes,4HCE6@91061|Bacilli 91061|Bacilli D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins - - - - - - - - - - - - ABC_tran,FtsK_SpoIIIE BJHFPPGC_00990 1005704.HMPREF9968_0034 5.02e-70 219.0 2ERR9@1|root,304NZ@2|Bacteria,1TWYQ@1239|Firmicutes,4I5TN@91061|Bacilli,1WPXP@1303|Streptococcus oralis 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_00991 699248.SRA_07801 1.26e-130 371.0 2D82H@1|root,32TQ8@2|Bacteria,1VDSV@1239|Firmicutes,4HSS8@91061|Bacilli 91061|Bacilli S Plasmid replication protein - - - - - - - - - - - - Rep_2 BJHFPPGC_00992 1035184.HMPREF1042_0937 2.2e-26 97.8 2DIMR@1|root,303NS@2|Bacteria,1TW0A@1239|Firmicutes,4I4NV@91061|Bacilli,42EH8@671232|Streptococcus anginosus group 91061|Bacilli S Domain of unknown function (DUF3173) - - - - - - - - - - - - DUF3173 BJHFPPGC_00993 904293.HMPREF9176_1601 6.35e-194 543.0 COG0582@1|root,COG0582@2|Bacteria,1UB49@1239|Firmicutes,4HCM3@91061|Bacilli 91061|Bacilli L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase BJHFPPGC_00994 904293.HMPREF9176_1601 9.71e-62 199.0 COG0582@1|root,COG0582@2|Bacteria,1UB49@1239|Firmicutes,4HCM3@91061|Bacilli 91061|Bacilli L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase BJHFPPGC_00995 1046629.Ssal_00994 7.74e-72 219.0 COG1670@1|root,COG1670@2|Bacteria,1V3NE@1239|Firmicutes,4HG1N@91061|Bacilli 91061|Bacilli J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins - - - ko:K03817 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 BJHFPPGC_00996 1046629.Ssal_00994 3.3e-30 111.0 COG1670@1|root,COG1670@2|Bacteria,1V3NE@1239|Firmicutes,4HG1N@91061|Bacilli 91061|Bacilli J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins - - - ko:K03817 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 BJHFPPGC_00997 904306.HMPREF9192_1827 3.31e-239 658.0 COG1064@1|root,COG1064@2|Bacteria,1TP5B@1239|Firmicutes,4HA9Z@91061|Bacilli 91061|Bacilli C alcohol dehydrogenase adhP - 1.1.1.1 ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N BJHFPPGC_00998 1046629.Ssal_00990 1.2e-59 184.0 2E660@1|root,330UP@2|Bacteria,1VFJD@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - BJHFPPGC_00999 435842.HMPREF0848_00770 1.39e-64 199.0 2E59Z@1|root,33028@2|Bacteria,1VFMU@1239|Firmicutes,4HQG9@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_01000 904306.HMPREF9192_1830 0.0 917.0 COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4HA1P@91061|Bacilli 91061|Bacilli L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII polYB - 2.7.7.7 ko:K02346,ko:K03502 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH BJHFPPGC_01001 1046629.Ssal_00988 2.51e-199 552.0 COG0834@1|root,COG0834@2|Bacteria,1TQNR@1239|Firmicutes 1239|Firmicutes ET ABC transporter substrate-binding protein aatB - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 BJHFPPGC_01002 1046629.Ssal_00987 2.15e-145 410.0 COG1126@1|root,COG1126@2|Bacteria,1UYAZ@1239|Firmicutes,4HE6M@91061|Bacilli 91061|Bacilli E abc transporter atp-binding protein glnQ - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran BJHFPPGC_01003 264199.stu0875 1.67e-135 385.0 COG0765@1|root,COG0765@2|Bacteria,1V280@1239|Firmicutes,4HGMH@91061|Bacilli 91061|Bacilli P ABC transporter (Permease yecS_2 - - ko:K02029,ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 BJHFPPGC_01004 1046629.Ssal_00985 7.1e-78 231.0 COG2824@1|root,COG2824@2|Bacteria,1V6NA@1239|Firmicutes,4HIKN@91061|Bacilli 91061|Bacilli P Alkylphosphonate utilization operon protein PhnA phnA - - ko:K06193 ko01120,map01120 - - - ko00000 - - - PhnA,PhnA_Zn_Ribbon BJHFPPGC_01005 1046629.Ssal_00983 0.0 1153.0 COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,4H9R4@91061|Bacilli 91061|Bacilli M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - iSB619.SA_RS11245,iYO844.BSU01780 GATase_6,SIS BJHFPPGC_01006 1046629.Ssal_00982 8.86e-214 590.0 COG0583@1|root,COG0583@2|Bacteria,1TP3E@1239|Firmicutes,4HC5J@91061|Bacilli 91061|Bacilli K Transcriptional regulator cpsY - - - - - - - - - - - HTH_1,LysR_substrate BJHFPPGC_01007 1046629.Ssal_00980 3.64e-160 449.0 COG1705@1|root,COG1705@2|Bacteria,1UYRM@1239|Firmicutes,4HAU6@91061|Bacilli 91061|Bacilli NU muramidase - - - ko:K02395,ko:K19223 - - - - ko00000,ko01000,ko01002,ko01011,ko02035 - CBM50 - Glucosaminidase,LysM BJHFPPGC_01008 1046629.Ssal_00979 2.29e-212 590.0 COG2855@1|root,COG2855@2|Bacteria,1TQYA@1239|Firmicutes 1239|Firmicutes S Membrane yeiH - - - - - - - - - - - Cons_hypoth698 BJHFPPGC_01011 1046629.Ssal_00976 0.0 1004.0 COG0803@1|root,COG3443@1|root,COG0803@2|Bacteria,COG3443@2|Bacteria,1TPG7@1239|Firmicutes,4H9UN@91061|Bacilli 91061|Bacilli P Belongs to the bacterial solute-binding protein 9 family adcA - - ko:K09815 ko02010,map02010 M00242 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.3,3.A.1.15.5 - - ZinT,ZnuA BJHFPPGC_01012 1046629.Ssal_00975 1.37e-182 509.0 COG2339@1|root,COG2339@2|Bacteria 2|Bacteria D peptidase activity XK27_10720 - - - - - - - - - - - PrsW-protease BJHFPPGC_01013 1046629.Ssal_00974 0.0 950.0 COG4690@1|root,COG4690@2|Bacteria,1TQ0F@1239|Firmicutes,4HC3G@91061|Bacilli 91061|Bacilli E Dipeptidase pepD - - ko:K08659 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C69 BJHFPPGC_01014 1046629.Ssal_00973 6.93e-207 573.0 COG1481@1|root,COG1481@2|Bacteria,1TP2X@1239|Firmicutes,4HB4H@91061|Bacilli 91061|Bacilli K May be required for sporulation whiA GO:0008150,GO:0043937,GO:0050789,GO:0050793,GO:0065007 - ko:K09762 - - - - ko00000 - - - HTH_WhiA,LAGLIDADG_WhiA,WhiA_N BJHFPPGC_01015 1046629.Ssal_00972 3.55e-231 636.0 COG0391@1|root,COG0391@2|Bacteria,1TPNV@1239|Firmicutes,4HA0Z@91061|Bacilli 91061|Bacilli S Required for morphogenesis under gluconeogenic growth conditions yvcK - - - - - - - - - - - UPF0052 BJHFPPGC_01016 1046629.Ssal_00971 5.72e-207 573.0 COG1660@1|root,COG1660@2|Bacteria,1TPS4@1239|Firmicutes,4H9KM@91061|Bacilli 91061|Bacilli S Displays ATPase and GTPase activities yvcJ - - ko:K06958 - - - - ko00000,ko03019 - - - ATP_bind_2 BJHFPPGC_01017 1046629.Ssal_00970 2.46e-172 482.0 COG4420@1|root,COG4420@2|Bacteria,1V46X@1239|Firmicutes,4HI49@91061|Bacilli 91061|Bacilli S cyclic nucleotide-binding protein yejC - - - - - - - - - - - DUF1003 BJHFPPGC_01018 1046629.Ssal_00969 2.21e-310 867.0 COG1196@1|root,COG1196@2|Bacteria 2|Bacteria D nuclear chromosome segregation - - - - - - - - - - - - DUF4297,PhageMin_Tail BJHFPPGC_01019 904306.HMPREF9192_1256 5.6e-123 349.0 COG0780@1|root,COG0780@2|Bacteria,1TPYC@1239|Firmicutes,4HB14@91061|Bacilli 91061|Bacilli S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily queF - 1.7.1.13 ko:K09457 ko00790,ko01100,map00790,map01100 - R07605 RC01875 ko00000,ko00001,ko01000,ko03016 - - - QueF BJHFPPGC_01020 904306.HMPREF9192_1255 8.72e-173 481.0 COG0602@1|root,COG0602@2|Bacteria,1TQ58@1239|Firmicutes,4HAJ3@91061|Bacilli 91061|Bacilli H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds queE GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008144,GO:0016829,GO:0016840,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:1901681,GO:1904047 4.3.99.3 ko:K10026 ko00790,ko01100,map00790,map01100 - R10002 RC02989 ko00000,ko00001,ko01000,ko03016 - - - Fer4_12,Fer4_14,Radical_SAM BJHFPPGC_01021 1046629.Ssal_00964 1.66e-105 304.0 COG0720@1|root,COG0720@2|Bacteria,1V9HU@1239|Firmicutes,4HJEX@91061|Bacilli 91061|Bacilli H synthase queD - 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 - - - PTPS BJHFPPGC_01022 1046629.Ssal_00963 1.3e-159 446.0 COG0603@1|root,COG0603@2|Bacteria,1TP4Z@1239|Firmicutes,4HB1Y@91061|Bacilli 91061|Bacilli F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) queC - 6.3.4.20 ko:K06920 ko00790,ko01100,map00790,map01100 - R09978 RC00959 ko00000,ko00001,ko01000,ko03016 - - - QueC BJHFPPGC_01023 1046629.Ssal_00962 9.11e-84 247.0 COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,4HKEF@91061|Bacilli 91061|Bacilli J endoribonuclease L-PSP aldR - 3.5.99.10 ko:K09022 - - R11098,R11099 RC03275,RC03354 ko00000,ko01000 - - - Ribonuc_L-PSP BJHFPPGC_01025 904306.HMPREF9192_1250 0.0 905.0 COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,4H9YH@91061|Bacilli 91061|Bacilli J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA asnS GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 ko:K01893 ko00970,map00970 M00359,M00360 R03648 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon BJHFPPGC_01026 264199.stu0817 3.38e-273 748.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli 91061|Bacilli E Aminotransferase aspB GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297 2.6.1.1,2.6.1.14 ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R01346,R02433,R02619,R05052 RC00006,RC00025 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 BJHFPPGC_01027 1046629.Ssal_00958 2.19e-95 280.0 COG5353@1|root,COG5353@2|Bacteria,1VA2H@1239|Firmicutes,4HNMM@91061|Bacilli 91061|Bacilli S Protein conserved in bacteria ypmB - - - - - - - - - - - PepSY BJHFPPGC_01028 1046629.Ssal_00957 0.0 1561.0 COG1199@1|root,COG2176@1|root,COG1199@2|Bacteria,COG2176@2|Bacteria,1TQHQ@1239|Firmicutes,4HB2Y@91061|Bacilli 91061|Bacilli L helicase involved in DNA repair and perhaps also replication dinG GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901576,GO:1902494,GO:1990234 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - DEAD,Helicase_C_2,RNase_T,ResIII BJHFPPGC_01029 1046629.Ssal_00954 3.05e-146 412.0 COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,4HHRQ@91061|Bacilli 91061|Bacilli S COG0491 Zn-dependent hydrolases, including glyoxylases yqgX - 3.1.2.6 ko:K01069 ko00620,map00620 - R01736 RC00004,RC00137 ko00000,ko00001,ko01000 - - - Lactamase_B BJHFPPGC_01030 904306.HMPREF9192_1244 5.77e-218 602.0 COG1079@1|root,COG1079@2|Bacteria,1TP8Y@1239|Firmicutes,4HAX4@91061|Bacilli 91061|Bacilli S Belongs to the binding-protein-dependent transport system permease family yufQ - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 BJHFPPGC_01031 904306.HMPREF9192_1243 1.53e-243 670.0 COG4603@1|root,COG4603@2|Bacteria,1TP1F@1239|Firmicutes,4H9VE@91061|Bacilli 91061|Bacilli S Belongs to the binding-protein-dependent transport system permease family mglC - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 BJHFPPGC_01032 1046629.Ssal_00951 0.0 953.0 COG3845@1|root,COG3845@2|Bacteria,1UYQA@1239|Firmicutes,4HVSH@91061|Bacilli 91061|Bacilli S ABC transporter, ATP-binding protein mglA - 3.6.3.17 ko:K02056,ko:K06400 - M00221 - - ko00000,ko00002,ko01000,ko02000 3.A.1.2 - - ABC_tran BJHFPPGC_01033 1046629.Ssal_00950 7.49e-240 661.0 COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,4HF7R@91061|Bacilli 91061|Bacilli S membrane - - - ko:K07335 - - - - ko00000 - - - Bmp BJHFPPGC_01034 904306.HMPREF9192_1240 2.46e-84 249.0 COG0295@1|root,COG0295@2|Bacteria,1V6IP@1239|Firmicutes,4HIJ3@91061|Bacilli 91061|Bacilli F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis cdd - 3.5.4.5 ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01878,R02485,R08221 RC00074,RC00514 ko00000,ko00001,ko01000 - - - dCMP_cyt_deam_1 BJHFPPGC_01035 1046629.Ssal_00948 1.2e-139 396.0 COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,4HAAJ@91061|Bacilli 91061|Bacilli F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate deoC GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 ko:K01619 ko00030,map00030 - R01066 RC00436,RC00437 ko00000,ko00001,ko01000 - - iSB619.SA_RS00835 DeoC BJHFPPGC_01036 1046629.Ssal_00947 2.8e-296 810.0 COG0213@1|root,COG0213@2|Bacteria,1TPCH@1239|Firmicutes,4H9NP@91061|Bacilli 91061|Bacilli F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate pdp GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2 ko:K00756 ko00240,ko01100,map00240,map01100 - R01570,R01876,R02296,R02484 RC00063 ko00000,ko00001,ko01000 - - - Glycos_trans_3N,Glycos_transf_3,PYNP_C BJHFPPGC_01037 1046629.Ssal_00946 3.21e-136 385.0 COG2813@1|root,COG2813@2|Bacteria,1V3JX@1239|Firmicutes,4IR00@91061|Bacilli 91061|Bacilli J Methyltransferase small domain protein rsmC - 2.1.1.172 ko:K00564 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - MTS BJHFPPGC_01038 1046629.Ssal_00945 4.78e-220 607.0 COG1072@1|root,COG1072@2|Bacteria,1TPHJ@1239|Firmicutes,4HA4K@91061|Bacilli 91061|Bacilli F Pantothenic acid kinase coaA GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.33 ko:K00867 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - PRK BJHFPPGC_01039 1046629.Ssal_00944 4.36e-40 133.0 COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,4HNJS@91061|Bacilli 91061|Bacilli J Binds directly to 16S ribosomal RNA rpsT - - ko:K02968 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S20p BJHFPPGC_01040 1046629.Ssal_00123 1.5e-115 330.0 COG1943@1|root,COG1943@2|Bacteria,1V1CM@1239|Firmicutes,4HBWU@91061|Bacilli 91061|Bacilli L COG1943 Transposase and inactivated derivatives - - - ko:K07491 - - - - ko00000 - - - Y1_Tnp BJHFPPGC_01041 904306.HMPREF9192_1072 1.11e-161 454.0 2EGU7@1|root,33AKD@2|Bacteria,1VMES@1239|Firmicutes,4HQPP@91061|Bacilli 91061|Bacilli S ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_4 BJHFPPGC_01042 1046629.Ssal_00789 7.61e-217 598.0 COG1131@1|root,COG1131@2|Bacteria,1TPBQ@1239|Firmicutes,4HAGA@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein bcrA - - ko:K01990,ko:K19309 ko02010,map02010 M00254,M00747 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.131.1 - - ABC_tran BJHFPPGC_01043 904306.HMPREF9192_1074 3.63e-289 792.0 COG1455@1|root,COG1455@2|Bacteria,1V5SI@1239|Firmicutes,4HJTK@91061|Bacilli 91061|Bacilli G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane celB - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - - PTS_EIIC BJHFPPGC_01044 904306.HMPREF9192_1075 8.05e-198 549.0 COG4814@1|root,COG4814@2|Bacteria,1V13S@1239|Firmicutes,4HENM@91061|Bacilli 91061|Bacilli E Alpha/beta hydrolase of unknown function (DUF915) - - - - - - - - - - - - DUF915 BJHFPPGC_01045 264199.stu1045 8.61e-291 795.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes 1239|Firmicutes L Transposase - - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 BJHFPPGC_01046 904306.HMPREF9192_1076 5.52e-96 280.0 COG1959@1|root,COG1959@2|Bacteria,1V6FK@1239|Firmicutes,4HKZD@91061|Bacilli 91061|Bacilli K Transcriptional regulator ywnA_2 - - - - - - - - - - - Rrf2 BJHFPPGC_01047 435842.HMPREF0848_00947 5.03e-195 541.0 COG2514@1|root,COG2514@2|Bacteria,1TPRF@1239|Firmicutes,4HAE7@91061|Bacilli 91061|Bacilli S glyoxalase catE - 1.13.11.2 ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 M00569 R00816,R04089,R05295,R05404,R05406,R07795 RC00387,RC00643,RC01075,RC01364,RC01914 ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase BJHFPPGC_01048 264199.stu1363 2.01e-141 399.0 COG3560@1|root,COG3560@2|Bacteria,1V1CR@1239|Firmicutes,4HD6W@91061|Bacilli 91061|Bacilli S nitroreductase XK27_02070 - - ko:K07078 - - - - ko00000 - - - Nitroreductase BJHFPPGC_01049 435842.HMPREF0848_00939 2.99e-219 605.0 COG4989@1|root,COG4989@2|Bacteria,1TQ12@1239|Firmicutes,4HA57@91061|Bacilli 91061|Bacilli S Aldo keto reductase ydhF - - - - - - - - - - - Aldo_ket_red BJHFPPGC_01050 889204.HMPREF9423_0305 7.66e-125 357.0 COG1309@1|root,COG1309@2|Bacteria,1V2BY@1239|Firmicutes,4HPW3@91061|Bacilli 91061|Bacilli K WHG domain - - - - - - - - - - - - TetR_N,WHG BJHFPPGC_01051 1114965.Spaf_1385 1.75e-157 442.0 COG1136@1|root,COG1136@2|Bacteria,1U3WD@1239|Firmicutes,4HV7M@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran BJHFPPGC_01052 888833.HMPREF9421_1062 5.93e-261 716.0 28K0P@1|root,2Z9QJ@2|Bacteria,1TSN2@1239|Firmicutes,4HU6K@91061|Bacilli 91061|Bacilli P FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX BJHFPPGC_01053 1046629.Ssal_00807 1.97e-56 175.0 COG4095@1|root,COG4095@2|Bacteria,1VBI9@1239|Firmicutes,4HN2M@91061|Bacilli 91061|Bacilli S Sugar efflux transporter for intercellular exchange - - - - - - - - - - - - MtN3_slv BJHFPPGC_01054 435842.HMPREF0848_00934 4.11e-110 317.0 COG0386@1|root,COG0386@2|Bacteria,1V3M3@1239|Firmicutes,4HH5Q@91061|Bacilli 91061|Bacilli O Belongs to the glutathione peroxidase family gpo - 1.11.1.9 ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 - R00274,R07034,R07035 RC00011,RC00982 ko00000,ko00001,ko01000 - - - GSHPx BJHFPPGC_01055 435842.HMPREF0848_00933 1.25e-219 608.0 COG0407@1|root,COG0407@2|Bacteria,1TNYE@1239|Firmicutes,4HQ5B@91061|Bacilli 91061|Bacilli H Uroporphyrinogen decarboxylase (URO-D) - - 4.1.1.37 ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03197,R04972 RC00872 ko00000,ko00001,ko00002,ko01000 - - - URO-D BJHFPPGC_01056 1046629.Ssal_00813 1.17e-211 584.0 COG0834@1|root,COG0834@2|Bacteria,1UX4B@1239|Firmicutes,4HG72@91061|Bacilli 91061|Bacilli ET ABC transporter substrate-binding protein - - - ko:K16957 ko02010,map02010 M00585 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.13 - - SBP_bac_3 BJHFPPGC_01057 435842.HMPREF0848_00931 5.53e-147 416.0 COG0765@1|root,COG0765@2|Bacteria,1V4Q3@1239|Firmicutes,4HDVS@91061|Bacilli 91061|Bacilli P ABC transporter (Permease - - - ko:K16958 ko02010,map02010 M00585 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.13 - - BPD_transp_1 BJHFPPGC_01058 1046629.Ssal_00815 1.12e-145 412.0 COG0765@1|root,COG0765@2|Bacteria,1V1PT@1239|Firmicutes,4HI18@91061|Bacilli 91061|Bacilli P ABC transporter, permease protein - - - ko:K16959 ko02010,map02010 M00585 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.13 - - BPD_transp_1 BJHFPPGC_01059 1046629.Ssal_00816 9.34e-176 490.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli 91061|Bacilli E abc transporter atp-binding protein tcyC2 - - ko:K10010,ko:K16960 ko02010,map02010 M00234,M00585 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3.10,3.A.1.3.13,3.A.1.3.14 - - ABC_tran BJHFPPGC_01060 1046629.Ssal_00817 0.0 1756.0 COG5263@1|root,COG5263@2|Bacteria 2|Bacteria S dextransucrase activity - - - - - - - - - - - - CW_binding_1,NLPC_P60,PG_binding_1 BJHFPPGC_01061 1046629.Ssal_00818 1.38e-295 811.0 COG0531@1|root,COG0531@2|Bacteria,1TQ4K@1239|Firmicutes,4HA66@91061|Bacilli 91061|Bacilli E amino acid yfnA - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 BJHFPPGC_01062 889204.HMPREF9423_1077 1.03e-67 208.0 COG4405@1|root,COG4405@2|Bacteria,1V6S0@1239|Firmicutes,4HKKR@91061|Bacilli,43G5A@68892|Streptococcus infantis 91061|Bacilli S ASCH - - - - - - - - - - - - ASCH BJHFPPGC_01063 1046629.Ssal_00820 2.81e-238 698.0 arCOG08054@1|root,2Z8AD@2|Bacteria,1TQ1J@1239|Firmicutes,4HDNN@91061|Bacilli 91061|Bacilli S Carbohydrate-binding domain-containing protein Cthe_2159 - - - - - - - - - - - - Cthe_2159 BJHFPPGC_01064 435842.HMPREF0848_00922 2.15e-27 100.0 COG3237@1|root,COG3237@2|Bacteria 2|Bacteria K CsbD-like csbD - - - - - - - - - - - CsbD BJHFPPGC_01065 1046629.Ssal_00823 6.04e-132 376.0 COG2323@1|root,COG2323@2|Bacteria,1UYR2@1239|Firmicutes,4HGVG@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF421) - - - - - - - - - - - - DUF421 BJHFPPGC_01066 1046629.Ssal_00824 1.03e-87 260.0 2C9NT@1|root,32V8Q@2|Bacteria,1VGVI@1239|Firmicutes,4IRUI@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF3290) - - - - - - - - - - - - DUF3290 BJHFPPGC_01067 904306.HMPREF9192_1083 2.14e-231 636.0 COG1482@1|root,COG1482@2|Bacteria,1VRGI@1239|Firmicutes,4HBFW@91061|Bacilli 91061|Bacilli G mannose-6-phosphate isomerase manA - 5.3.1.8 ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01819 RC00376 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU12020 PMI_typeI BJHFPPGC_01068 1046629.Ssal_00826 1.05e-294 807.0 COG1114@1|root,COG1114@2|Bacteria,1TQIS@1239|Firmicutes,4HAKA@91061|Bacilli 91061|Bacilli E Component of the transport system for branched-chain amino acids brnQ GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903785,GO:1903825,GO:1905039 - ko:K03311 - - - - ko00000 2.A.26 - - Branch_AA_trans BJHFPPGC_01069 888821.HMPREF9394_1376 9.42e-160 478.0 COG0699@1|root,COG0699@2|Bacteria 2|Bacteria T ATPase. Has a role at an early stage in the morphogenesis of the spore coat - - - - - - - - - - - - Dynamin_N,LXG,MMR_HSR1 BJHFPPGC_01070 888821.HMPREF9394_1375 0.0 1471.0 COG0433@1|root,COG0433@2|Bacteria,1TQPR@1239|Firmicutes,4HCUM@91061|Bacilli 91061|Bacilli S Domain of unknown function DUF87 - - - - - - - - - - - - DUF87 BJHFPPGC_01071 888821.HMPREF9394_1374 8.55e-61 194.0 COG3210@1|root,COG3210@2|Bacteria,1VEK5@1239|Firmicutes,4HPFJ@91061|Bacilli 91061|Bacilli U A nuclease of the HNH/ENDO VII superfamily with conserved LHH - - - - - - - - - - - - LHH BJHFPPGC_01072 888821.HMPREF9394_1373 3.32e-51 166.0 2ES07@1|root,33JJA@2|Bacteria,1VMQG@1239|Firmicutes 1239|Firmicutes S SMI1-KNR4 cell-wall - - - - - - - - - - - - SUKH_5 BJHFPPGC_01073 1046629.Ssal_00827 5.85e-226 622.0 COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,1TQ3E@1239|Firmicutes,4HAIV@91061|Bacilli 91061|Bacilli O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrA - 1.8.4.11,1.8.4.12 ko:K12267 - - - - ko00000,ko01000 - - - PMSR,SelR BJHFPPGC_01075 904306.HMPREF9192_1086 9.42e-313 853.0 COG0534@1|root,COG0534@2|Bacteria,1TP5U@1239|Firmicutes,4HA4W@91061|Bacilli 91061|Bacilli V Multidrug efflux pump norM GO:0003674,GO:0005215,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015893,GO:0022857,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085 - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE BJHFPPGC_01076 435842.HMPREF0848_00915 1.12e-183 512.0 COG1396@1|root,COG1396@2|Bacteria 2|Bacteria K sequence-specific DNA binding - - - ko:K20373 ko02024,map02024 - - - ko00000,ko00001,ko03000 - - - HTH_3,HTH_31 BJHFPPGC_01077 435842.HMPREF0848_00914 0.0 957.0 COG1132@1|root,COG1132@2|Bacteria 2|Bacteria V (ABC) transporter - - - ko:K06148 - - - - ko00000,ko02000 3.A.1 - - ABC_membrane,ABC_tran BJHFPPGC_01078 435842.HMPREF0848_00913 2.96e-284 779.0 COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,4HBAM@91061|Bacilli 91061|Bacilli F xanthine permease pbuX GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006863,GO:0008150,GO:0015205,GO:0015851,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042906,GO:0042907,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:1904823 - ko:K16169 - - - - ko00000,ko02000 2.A.40.3.1 - iSB619.SA_RS02140 Xan_ur_permease BJHFPPGC_01079 1046629.Ssal_00834 3.59e-127 362.0 COG0503@1|root,COG0503@2|Bacteria,1V1DU@1239|Firmicutes,4HFNW@91061|Bacilli 91061|Bacilli F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis xpt - 2.4.2.22 ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 - R01229,R02142 RC00063,RC00122 ko00000,ko00001,ko01000 - - iYO844.BSU22070 Pribosyltran BJHFPPGC_01080 1046629.Ssal_00835 3.69e-159 446.0 COG0745@1|root,COG0745@2|Bacteria,1TR32@1239|Firmicutes,4HAUJ@91061|Bacilli 91061|Bacilli KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain graR - - ko:K19082 ko02020,map02020 M00734,M00737 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C BJHFPPGC_01081 264199.stu1335 7.87e-219 605.0 COG0642@1|root,COG0642@2|Bacteria,1TQSG@1239|Firmicutes,4HG2J@91061|Bacilli 91061|Bacilli T Histidine kinase - - - - - - - - - - - - HATPase_c BJHFPPGC_01082 435842.HMPREF0848_00909 3.5e-170 476.0 COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,4H9UT@91061|Bacilli 91061|Bacilli V ABC transporter, ATP-binding protein yxdL - - ko:K02003,ko:K19083 ko02010,ko02020,map02010,map02020 M00258,M00731,M00737 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.134 - - ABC_tran BJHFPPGC_01083 435842.HMPREF0848_00908 0.0 1175.0 COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,4H9SH@91061|Bacilli 91061|Bacilli V ABC transporter (permease) - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX BJHFPPGC_01084 435842.HMPREF0848_00907 1.17e-120 343.0 COG0727@1|root,COG0727@2|Bacteria 2|Bacteria S metal cluster binding XK27_05000 - - ko:K06940 - - - - ko00000 - - - CxxCxxCC BJHFPPGC_01087 1046629.Ssal_00842 2.7e-199 553.0 COG1131@1|root,COG1131@2|Bacteria,1UZ04@1239|Firmicutes,4HDGQ@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein XK27_09825 - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran BJHFPPGC_01088 1046629.Ssal_00843 2.11e-147 418.0 COG0842@1|root,COG0842@2|Bacteria,1V1AU@1239|Firmicutes,4HHQW@91061|Bacilli 91061|Bacilli V Transporter - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane,ABC2_membrane_3 BJHFPPGC_01089 264199.stu1331 5.76e-107 308.0 COG0295@1|root,COG0295@2|Bacteria,1V58S@1239|Firmicutes,4HHTM@91061|Bacilli 91061|Bacilli F cytidine deaminase activity - - - - - - - - - - - - dCMP_cyt_deam_1 BJHFPPGC_01090 904306.HMPREF9192_1097 4.53e-212 587.0 COG0385@1|root,COG0385@2|Bacteria,1TP85@1239|Firmicutes,4HBG6@91061|Bacilli 91061|Bacilli S Transporter yocS - - ko:K03453 - - - - ko00000 2.A.28 - iYO844.BSU19350 SBF BJHFPPGC_01091 435842.HMPREF0848_00901 0.0 1123.0 COG0443@1|root,COG0443@2|Bacteria,1TQ6N@1239|Firmicutes,4HCZX@91061|Bacilli 91061|Bacilli O Belongs to the heat shock protein 70 family hscC - - ko:K04045 - - - - ko00000,ko03110 1.A.33 - - HSP70 BJHFPPGC_01092 435842.HMPREF0848_00900 5.96e-301 823.0 COG0666@1|root,COG0666@2|Bacteria 2|Bacteria G response to abiotic stimulus anK3 - - ko:K07126 - - - - ko00000 - - - Ank_2,Ank_3,Ank_4,DUF1835,SUFU BJHFPPGC_01094 1316408.HSISM1_1160 1.13e-263 727.0 COG1819@1|root,COG1819@2|Bacteria 2|Bacteria CG transferase activity, transferring hexosyl groups - - 2.4.1.276 ko:K14596 ko00906,map00906 - R07574 RC00005,RC01992 ko00000,ko00001,ko01000,ko01003 - GT1 - Glyco_tran_28_C,Glyco_trans_1_3,UDPGT BJHFPPGC_01095 999425.HMPREF9186_00186 1.01e-127 366.0 28MX1@1|root,2ZB48@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - BJHFPPGC_01096 888048.HMPREF8577_0487 7.63e-252 693.0 COG1215@1|root,COG1215@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups ugcG - 2.4.1.80 ko:K00720 ko00600,ko01100,map00600,map01100 M00066 R01497 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko02000 4.D.1.4 GT21 - Glyco_transf_21 BJHFPPGC_01097 999425.HMPREF9186_00184 2.8e-135 388.0 COG0300@1|root,COG0300@2|Bacteria 2|Bacteria S Belongs to the short-chain dehydrogenases reductases (SDR) family - - 1.1.1.105 ko:K07124,ko:K15734 ko00830,map00830 - R02124 RC00649 ko00000,ko00001,ko01000 - - - adh_short BJHFPPGC_01098 435842.HMPREF0848_00898 1.5e-294 805.0 COG1819@1|root,COG1819@2|Bacteria,1V064@1239|Firmicutes,4HUGZ@91061|Bacilli 91061|Bacilli CG Glycosyltransferase family 28 C-terminal domain - - - - - - - - - - - - Glyco_tran_28_C BJHFPPGC_01099 435842.HMPREF0848_00897 2.68e-227 627.0 COG0451@1|root,COG0451@2|Bacteria,1TT3X@1239|Firmicutes,4HFYX@91061|Bacilli 91061|Bacilli M NAD dependent epimerase dehydratase family protein galE1 - - - - - - - - - - - 3Beta_HSD,Epimerase BJHFPPGC_01100 435842.HMPREF0848_00896 9.49e-198 547.0 COG0491@1|root,COG0491@2|Bacteria,1V5YS@1239|Firmicutes,4HIA8@91061|Bacilli 91061|Bacilli S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B BJHFPPGC_01101 435842.HMPREF0848_00895 2.01e-306 835.0 COG1541@1|root,COG1541@2|Bacteria,1UYWT@1239|Firmicutes,4HD2R@91061|Bacilli 91061|Bacilli H Coenzyme F390 synthetase - - - - - - - - - - - - AMP-binding BJHFPPGC_01102 435842.HMPREF0848_00894 1.54e-220 608.0 COG0332@1|root,COG0332@2|Bacteria,1UYNP@1239|Firmicutes,4HECC@91061|Bacilli 91061|Bacilli I synthase III fabH - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C BJHFPPGC_01105 322159.STER_1293 7.21e-204 565.0 COG1131@1|root,COG1131@2|Bacteria,1UZ04@1239|Firmicutes 1239|Firmicutes V 'abc transporter, ATP-binding protein XK27_09825 - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran BJHFPPGC_01106 322159.STER_1292 4.12e-170 475.0 COG0842@1|root,COG0842@2|Bacteria,1V1AU@1239|Firmicutes 1239|Firmicutes V ABC-2 type transporter - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane,ABC2_membrane_3 BJHFPPGC_01107 904306.HMPREF9192_1102 2.21e-236 653.0 COG4585@1|root,COG4585@2|Bacteria,1TSUE@1239|Firmicutes,4HB9N@91061|Bacilli 91061|Bacilli T Histidine kinase desK GO:0003674,GO:0003824,GO:0004721,GO:0005488,GO:0005515,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0036211,GO:0042578,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 ko:K07778 ko02020,map02020 M00479 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA_3 BJHFPPGC_01108 904306.HMPREF9192_1103 1.7e-133 379.0 COG2197@1|root,COG2197@2|Bacteria,1TVTF@1239|Firmicutes,4HAJW@91061|Bacilli 91061|Bacilli K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain desR - - ko:K02479,ko:K07693 ko02020,map02020 M00479 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg BJHFPPGC_01109 563038.HMPREF0851_00491 6.83e-260 724.0 COG1479@1|root,COG1479@2|Bacteria,1TSBG@1239|Firmicutes,4HUFT@91061|Bacilli 91061|Bacilli S Protein of unknown function DUF262 - - - - - - - - - - - - DUF1524,DUF262 BJHFPPGC_01110 1196322.A370_02674 2.45e-147 451.0 COG1479@1|root,COG1479@2|Bacteria,1TRXF@1239|Firmicutes,24ET3@186801|Clostridia,36NWE@31979|Clostridiaceae 186801|Clostridia S Protein of unknown function DUF262 - - - - - - - - - - - - DUF262 BJHFPPGC_01111 1046629.Ssal_00505 1.49e-112 337.0 COG2378@1|root,COG2378@2|Bacteria 2|Bacteria K regulation of single-species biofilm formation yfjR GO:0008150,GO:0043900,GO:0050789,GO:0050794,GO:0065007,GO:1900190 - - - - - - - - - - HTH_11,HTH_DeoR,WYL BJHFPPGC_01114 1316408.HSISM1_386 7.81e-238 654.0 COG4586@1|root,COG4586@2|Bacteria,1TP1N@1239|Firmicutes,4H9NR@91061|Bacilli 91061|Bacilli S abc transporter atp-binding protein - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran BJHFPPGC_01115 1005705.HMPREF9967_1430 1.27e-182 509.0 COG4587@1|root,COG4587@2|Bacteria,1TSAN@1239|Firmicutes,4HBVU@91061|Bacilli,43FGB@68892|Streptococcus infantis 91061|Bacilli S ABC-2 family transporter protein M1-956 - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_6 BJHFPPGC_01116 904306.HMPREF9192_1106 6.34e-182 506.0 COG3694@1|root,COG3694@2|Bacteria,1US4C@1239|Firmicutes,4IRS2@91061|Bacilli 91061|Bacilli S ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_6 BJHFPPGC_01117 888746.HMPREF9180_0560 5.89e-100 290.0 COG0454@1|root,COG0454@2|Bacteria,1V1JN@1239|Firmicutes,4HMYM@91061|Bacilli 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_10,Acetyltransf_7 BJHFPPGC_01118 904306.HMPREF9192_1107 0.0 4088.0 COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli 91061|Bacilli O Belongs to the peptidase S8 family prtA - - - - - - - - - - - Gram_pos_anchor,Inhibitor_I9,PA,Peptidase_S8,fn3_5 BJHFPPGC_01119 873449.STRCR_1470 1.38e-65 205.0 COG2249@1|root,COG2249@2|Bacteria,1V4UF@1239|Firmicutes,4HH6R@91061|Bacilli 91061|Bacilli S general stress protein ywrO - - ko:K11748 - - - - ko00000,ko02000 2.A.37.1.2 - - Flavodoxin_2 BJHFPPGC_01120 1046629.Ssal_00862 7.17e-204 565.0 COG1396@1|root,COG1396@2|Bacteria 2|Bacteria K sequence-specific DNA binding - - - ko:K20342,ko:K20480 ko02024,map02024 - - - ko00000,ko00001,ko03000 - - - HTH_19,HTH_3,TPR_8 BJHFPPGC_01121 888048.HMPREF8577_0354 2.81e-104 303.0 COG1714@1|root,COG1714@2|Bacteria,1V7WG@1239|Firmicutes,4HK3X@91061|Bacilli 91061|Bacilli S RDD family - - - - - - - - - - - - RDD BJHFPPGC_01122 1046629.Ssal_00868 3.05e-207 574.0 COG0697@1|root,COG0697@2|Bacteria,1TP9B@1239|Firmicutes,4H9TT@91061|Bacilli 91061|Bacilli EG membrane yjlA - - - - - - - - - - - EmrE BJHFPPGC_01123 1046629.Ssal_00871 0.0 2353.0 COG1621@1|root,COG3583@1|root,COG5492@1|root,COG1621@2|Bacteria,COG3583@2|Bacteria,COG5492@2|Bacteria,1TS4M@1239|Firmicutes 1239|Firmicutes G Belongs to the glycosyl hydrolase 32 family - - 3.2.1.80 ko:K03332 ko00051,map00051 - R00879 - ko00000,ko00001,ko01000 - - - Big_2,CW_binding_1,Cadherin-like,DUF1080,G5,Glyco_hydro_32C,Glyco_hydro_32N,Gram_pos_anchor,Laminin_G_2 BJHFPPGC_01124 1046629.Ssal_00873 1.12e-189 528.0 COG1760@1|root,COG1760@2|Bacteria,1TP79@1239|Firmicutes,4HAI1@91061|Bacilli 91061|Bacilli E L-serine dehydratase sdaAA - 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - SDH_alpha BJHFPPGC_01125 1046629.Ssal_00874 5.22e-153 430.0 COG1760@1|root,COG1760@2|Bacteria,1U8TZ@1239|Firmicutes,4HBD6@91061|Bacilli 91061|Bacilli E L-serine dehydratase sdaAB - 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - ACT,SDH_beta BJHFPPGC_01126 904306.HMPREF9192_1465 3.81e-159 446.0 COG1011@1|root,COG1011@2|Bacteria,1TWM7@1239|Firmicutes,4HEXU@91061|Bacilli 91061|Bacilli E hydrolase yfnB - 3.8.1.2 ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - HAD_2 BJHFPPGC_01127 1046629.Ssal_00877 0.0 1174.0 COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,4H9QH@91061|Bacilli 91061|Bacilli L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N BJHFPPGC_01128 904306.HMPREF9192_1468 0.0 942.0 COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,4H9TI@91061|Bacilli 91061|Bacilli I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol cls GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0071704,GO:0090407,GO:1901576 - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2,PLDc_N BJHFPPGC_01129 1046629.Ssal_00879 2.18e-116 333.0 COG1247@1|root,COG1247@2|Bacteria,1V6X5@1239|Firmicutes,4HIP1@91061|Bacilli 91061|Bacilli M acetyltransferase pat - 2.3.1.183 ko:K03823 ko00440,ko01130,map00440,map01130 - R08871,R08938 RC00004,RC00064 ko00000,ko00001,ko01000 - - - Acetyltransf_4 BJHFPPGC_01130 1114965.Spaf_1082 0.0 974.0 COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,4H9TI@91061|Bacilli 91061|Bacilli I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol clsA_1 GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0071704,GO:0090407,GO:1901576 - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2,PLDc_N BJHFPPGC_01132 1046629.Ssal_00883 5.02e-255 699.0 COG0136@1|root,COG0136@2|Bacteria,1TPC6@1239|Firmicutes,4HA9H@91061|Bacilli 91061|Bacilli E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd - 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC BJHFPPGC_01133 1046629.Ssal_00884 8.96e-223 614.0 COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,4H9K9@91061|Bacilli 91061|Bacilli E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS BJHFPPGC_01134 1046629.Ssal_00886 1.52e-159 447.0 COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,4HAWU@91061|Bacilli 91061|Bacilli J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm BJHFPPGC_01135 1046629.Ssal_00887 0.0 1684.0 COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,4HB89@91061|Bacilli 91061|Bacilli D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge BJHFPPGC_01136 1046629.Ssal_00888 1.32e-114 330.0 2EQR3@1|root,33IAY@2|Bacteria,1VK6G@1239|Firmicutes,4HRX8@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF3278) - - - - - - - - - - - - DUF3278 BJHFPPGC_01137 1000570.HMPREF9966_0177 1.06e-31 111.0 COG1476@1|root,COG1476@2|Bacteria,1VERT@1239|Firmicutes,4HNKW@91061|Bacilli,42DRV@671232|Streptococcus anginosus group 91061|Bacilli K Helix-turn-helix domain WQ51_00220 - - ko:K07729 - - - - ko00000,ko03000 - - - HTH_3 BJHFPPGC_01138 1046629.Ssal_00890 1.96e-251 689.0 COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,4HAVN@91061|Bacilli 91061|Bacilli J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Phe_tRNA-synt_N,tRNA-synt_2d BJHFPPGC_01139 1046629.Ssal_00891 2.07e-118 338.0 COG0454@1|root,COG0456@2|Bacteria,1VDFK@1239|Firmicutes,4HMHW@91061|Bacilli 91061|Bacilli K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases XK27_03150 - 2.3.1.57 ko:K22441 - - - - ko00000,ko01000 - - - Acetyltransf_1,Acetyltransf_10 BJHFPPGC_01140 904306.HMPREF9192_1479 0.0 1538.0 COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1TP98@1239|Firmicutes,4HAQ9@91061|Bacilli 91061|Bacilli J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily pheT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind BJHFPPGC_01142 1046629.Ssal_00894 6.52e-75 224.0 COG0209@1|root,COG0209@2|Bacteria,1TT3U@1239|Firmicutes 1239|Firmicutes F Ribonucleoside-triphosphate reductase nrdD_1 - 1.1.98.6,1.17.4.1 ko:K00525,ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024,R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,Ribonuc_red_lgC BJHFPPGC_01143 904306.HMPREF9192_1482 3.17e-267 736.0 COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,4HBNK@91061|Bacilli 91061|Bacilli K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs ycxD - - - - - - - - - - - Aminotran_1_2,GntR BJHFPPGC_01145 904306.HMPREF9192_1484 5.05e-104 302.0 COG4720@1|root,COG4720@2|Bacteria,1V6QK@1239|Firmicutes 1239|Firmicutes S ECF-type riboflavin transporter, S component - - - - - - - - - - - - ECF-ribofla_trS BJHFPPGC_01146 1046629.Ssal_00899 5.32e-170 478.0 COG2240@1|root,COG2240@2|Bacteria,1TRCR@1239|Firmicutes,4HHME@91061|Bacilli 91061|Bacilli H Belongs to the pyridoxine kinase family pdxK - 2.7.1.35 ko:K00868 ko00750,ko01100,map00750,map01100 - R00174,R01909,R02493 RC00002,RC00017 ko00000,ko00001,ko01000 - - - Phos_pyr_kin BJHFPPGC_01147 904306.HMPREF9192_1486 7.32e-105 305.0 COG4720@1|root,COG4720@2|Bacteria,1VC0F@1239|Firmicutes,4HMJM@91061|Bacilli 91061|Bacilli S ECF-type riboflavin transporter, S component - - - - - - - - - - - - ECF-ribofla_trS BJHFPPGC_01148 904306.HMPREF9192_1487 0.0 1005.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HC58@91061|Bacilli 91061|Bacilli S abc transporter atp-binding protein yheS_1 - - - - - - - - - - - ABC_tran,ABC_tran_Xtn BJHFPPGC_01149 1046629.Ssal_00902 0.0 883.0 COG0446@1|root,COG0446@2|Bacteria,1TPWW@1239|Firmicutes,4H9U7@91061|Bacilli 91061|Bacilli P NADH oxidase noxE - - - - - - - - - - - Pyr_redox_2,Pyr_redox_dim BJHFPPGC_01150 1046629.Ssal_00903 2.06e-232 640.0 COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,4HB0Z@91061|Bacilli 91061|Bacilli C Belongs to the LDH MDH superfamily. LDH family ldh - 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 - R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N BJHFPPGC_01151 1046629.Ssal_00904 0.0 1476.0 COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,4HAHY@91061|Bacilli 91061|Bacilli L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV BJHFPPGC_01152 1046629.Ssal_00905 3.78e-170 476.0 COG3764@1|root,COG3764@2|Bacteria,1V83Z@1239|Firmicutes,4HIA0@91061|Bacilli 91061|Bacilli M Sortase (surface protein transpeptidase) srtA - 3.4.22.70 ko:K07284 - - - - ko00000,ko01000,ko01002,ko01011 - - - Sortase BJHFPPGC_01153 1046629.Ssal_00906 8.71e-93 271.0 COG0346@1|root,COG0346@2|Bacteria,1V6XU@1239|Firmicutes,4HIFI@91061|Bacilli 91061|Bacilli E COG0346 Lactoylglutathione lyase and related lyases ywkD - - ko:K08234 - - - - ko00000 - - - Glyoxalase BJHFPPGC_01154 1046629.Ssal_00907 7.38e-207 575.0 COG4086@1|root,COG4086@2|Bacteria,1TR2I@1239|Firmicutes,4HBVZ@91061|Bacilli 91061|Bacilli S secreted protein ypuA - - - - - - - - - - - DUF1002 BJHFPPGC_01155 1046629.Ssal_00908 3.67e-293 801.0 COG1914@1|root,COG1914@2|Bacteria,1V04N@1239|Firmicutes,4HBF6@91061|Bacilli 91061|Bacilli P Mn2 and Fe2 transporters of the NRAMP family mntH_2 - - - - - - - - - - - Nramp BJHFPPGC_01156 1046629.Ssal_00910 3.52e-61 187.0 COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,4HNQF@91061|Bacilli 91061|Bacilli J 50S ribosomal protein L31 rpmE - - ko:K02909 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L31 BJHFPPGC_01157 1046629.Ssal_00912 3.52e-224 617.0 COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,4HDFE@91061|Bacilli 91061|Bacilli H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein apbE - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE BJHFPPGC_01158 1046629.Ssal_00913 1.44e-225 621.0 COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,4H9ZW@91061|Bacilli 91061|Bacilli S domain protein nrnA - 3.1.13.3,3.1.3.7 ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 BJHFPPGC_01159 1046629.Ssal_00914 5.08e-193 535.0 COG0625@1|root,COG0625@2|Bacteria,1TPZ7@1239|Firmicutes,4HD0K@91061|Bacilli 91061|Bacilli O Glutathione S-transferase gst - - ko:K11209 - - - - ko00000,ko01000 - - - GST_C,GST_C_2,GST_N,GST_N_2 BJHFPPGC_01160 1046629.Ssal_00915 3.42e-235 647.0 COG1816@1|root,COG1816@2|Bacteria,1U44B@1239|Firmicutes,4HCES@91061|Bacilli 91061|Bacilli F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism add - 3.5.4.2,3.5.4.4 ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 M00236 R01244,R01560,R02556 RC00477 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 - - A_deaminase BJHFPPGC_01161 904306.HMPREF9192_1209 5.81e-141 398.0 COG1435@1|root,COG1435@2|Bacteria,1TRVM@1239|Firmicutes,4HA4A@91061|Bacilli 91061|Bacilli F thymidine kinase tdk GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01567,R02099,R08233 RC00002,RC00017 ko00000,ko00001,ko01000 - - - TK BJHFPPGC_01162 1046629.Ssal_00917 4.58e-247 679.0 COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,4H9MB@91061|Bacilli 91061|Bacilli J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA - - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 BJHFPPGC_01163 1046629.Ssal_00918 5.82e-186 518.0 COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,4HC6W@91061|Bacilli 91061|Bacilli J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif prmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 ko:K02493 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03012 - - - MTS BJHFPPGC_01164 1046629.Ssal_00919 4.33e-134 380.0 COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,4HA7W@91061|Bacilli 91061|Bacilli J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine ywlC GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - SUA5,Sua5_yciO_yrdC BJHFPPGC_01165 904306.HMPREF9192_1213 3.5e-289 791.0 COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,4HA5K@91061|Bacilli 91061|Bacilli E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA - 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT BJHFPPGC_01166 904306.HMPREF9192_1214 3.67e-229 631.0 COG3081@1|root,COG3081@2|Bacteria,1V437@1239|Firmicutes,4IQXJ@91061|Bacilli 91061|Bacilli S 37-kD nucleoid-associated bacterial protein - - - - - - - - - - - - NA37 BJHFPPGC_01167 264199.stu0757 1.77e-127 365.0 COG0741@1|root,COG0741@2|Bacteria 2|Bacteria M lytic transglycosylase activity pvaA - - ko:K02395 - - - - ko00000,ko02035 - - - Lysozyme_like,SLT_2 BJHFPPGC_01168 904306.HMPREF9192_1216 0.0 1011.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H9SC@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein yfiB1 - - ko:K06147,ko:K06148 - - - - ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran BJHFPPGC_01169 1046629.Ssal_00924 0.0 1078.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HCVN@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein XK27_10035 - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran BJHFPPGC_01170 1046629.Ssal_00926 0.0 1025.0 COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,4HAHU@91061|Bacilli 91061|Bacilli Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall dltA GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016208,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0022857,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.13 ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 M00725 R02718 RC00037,RC00094 ko00000,ko00001,ko00002,ko01000,ko01504 - - - AMP-binding,AMP-binding_C BJHFPPGC_01171 1046629.Ssal_00927 1.03e-301 822.0 COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,4HBQG@91061|Bacilli 91061|Bacilli M Membrane protein involved in D-alanine export dltB - - ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00725 - - ko00000,ko00001,ko00002,ko01504 - - - MBOAT BJHFPPGC_01172 1046629.Ssal_00928 5.82e-47 150.0 COG0236@1|root,COG0236@2|Bacteria,1VFQI@1239|Firmicutes,4HNIH@91061|Bacilli 91061|Bacilli IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall dltC GO:0000270,GO:0003674,GO:0005215,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0022857,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.1.1.13 ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 M00725 R02718 RC00037,RC00094 ko00000,ko00001,ko00002,ko01000,ko01504 - - - PP-binding BJHFPPGC_01173 1046629.Ssal_00929 3.43e-299 816.0 COG3966@1|root,COG3966@2|Bacteria,1TSZU@1239|Firmicutes,4HC3H@91061|Bacilli 91061|Bacilli M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) dltD - - ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00725 - - ko00000,ko00001,ko00002,ko01504 - - - DltD BJHFPPGC_01174 1046629.Ssal_00930 0.0 1636.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9S5@91061|Bacilli 91061|Bacilli P cation transport ATPase - - 3.6.3.2,3.6.3.6,3.6.3.8 ko:K01531,ko:K01535,ko:K01537 ko00190,map00190 - - - ko00000,ko00001,ko01000 3.A.3.2,3.A.3.3,3.A.3.4 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 BJHFPPGC_01175 1046629.Ssal_00931 0.0 1081.0 COG0115@1|root,COG0147@1|root,COG0115@2|Bacteria,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,4HBKC@91061|Bacilli 91061|Bacilli EH component I pabB - 2.6.1.85,4.1.3.38 ko:K01665,ko:K03342,ko:K13950 ko00790,map00790 - R01716,R05553 RC00010,RC01418,RC01843,RC02148 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_4,Chorismate_bind BJHFPPGC_01177 1046629.Ssal_00933 0.0 1483.0 COG0620@1|root,COG0620@2|Bacteria,1TP2H@1239|Firmicutes,4H9QC@91061|Bacilli 91061|Bacilli E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation metE GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_1,Meth_synt_2 BJHFPPGC_01178 1046629.Ssal_00934 8.88e-213 587.0 COG0685@1|root,COG0685@2|Bacteria,1TQFE@1239|Firmicutes 1239|Firmicutes E reductase metF - 1.5.1.20 ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 - - - MTHFR BJHFPPGC_01179 1046629.Ssal_00935 0.0 1123.0 COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,4HADU@91061|Bacilli 91061|Bacilli G Phosphoglucomutase pgm - 5.4.2.2 ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00549 R00959,R01057,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV BJHFPPGC_01180 1046629.Ssal_00936 2.85e-116 334.0 COG4684@1|root,COG4684@2|Bacteria,1V2M1@1239|Firmicutes 1239|Firmicutes S Psort location CytoplasmicMembrane, score - - - - - - - - - - - - ECF_trnsprt BJHFPPGC_01181 1046629.Ssal_00938 3.72e-121 347.0 COG4684@1|root,COG4684@2|Bacteria,1V2M1@1239|Firmicutes,4HFPD@91061|Bacilli 91061|Bacilli S ECF transporter, substrate-specific component - - - - - - - - - - - - ECF_trnsprt BJHFPPGC_01182 1046629.Ssal_00939 2.12e-120 344.0 COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4HAK8@91061|Bacilli 91061|Bacilli H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine coaBC - 4.1.1.36,6.3.2.5 ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - - DFP,Flavoprotein BJHFPPGC_01183 1046629.Ssal_00940 7.94e-150 422.0 COG0452@1|root,COG0452@2|Bacteria,1V7YG@1239|Firmicutes,4HMIF@91061|Bacilli 91061|Bacilli H Phosphopantothenate-cysteine ligase coaB - 6.3.2.5 ko:K21977 ko00770,map00770 M00120 R04231 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - DFP BJHFPPGC_01184 1046629.Ssal_00941 0.0 1090.0 COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,4HA2X@91061|Bacilli 91061|Bacilli F Belongs to the formate--tetrahydrofolate ligase family fhs - 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 - - - FTHFS BJHFPPGC_01185 1046629.Ssal_00942 2.39e-154 434.0 COG0745@1|root,COG0745@2|Bacteria,1V295@1239|Firmicutes,4HG3X@91061|Bacilli 91061|Bacilli T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain ciaR - - ko:K14983 ko02020,ko02024,map02020,map02024 M00521 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C BJHFPPGC_01186 904306.HMPREF9192_1234 7.11e-310 848.0 COG0642@1|root,COG2205@2|Bacteria,1UHNC@1239|Firmicutes,4IS4A@91061|Bacilli 91061|Bacilli T Histidine kinase ciaH - 2.7.13.3 ko:K14982 ko02020,ko02024,map02020,map02024 M00521 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA BJHFPPGC_01188 1046629.Ssal_02044 1.31e-113 326.0 COG1595@1|root,COG1595@2|Bacteria 2|Bacteria K DNA-templated transcription, initiation sigH - - ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001,ko03000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 BJHFPPGC_01189 1046629.Ssal_02043 2.18e-174 488.0 COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,4HCB8@91061|Bacilli 91061|Bacilli M mechanosensitive ion channel ykuT GO:0003674,GO:0005215,GO:0006810,GO:0006950,GO:0006970,GO:0008150,GO:0008381,GO:0009628,GO:0009987,GO:0015267,GO:0022803,GO:0022836,GO:0022857,GO:0033554,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071214,GO:0071470,GO:0104004 - ko:K16052,ko:K22044 - - - - ko00000,ko02000 1.A.23.3,1.A.23.4 - - MS_channel BJHFPPGC_01190 1046629.Ssal_02041 3e-291 797.0 COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,4H9Q8@91061|Bacilli 91061|Bacilli D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N BJHFPPGC_01191 1046629.Ssal_02039 1.24e-101 298.0 COG3343@1|root,COG3343@2|Bacteria,1V6WX@1239|Firmicutes,4HIUK@91061|Bacilli 91061|Bacilli K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling rpoE - - ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 - - - HARE-HTH BJHFPPGC_01192 1046629.Ssal_02036 0.0 1060.0 COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,4H9X6@91061|Bacilli 91061|Bacilli F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG - 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - - CTP_synth_N,GATase BJHFPPGC_01193 1046629.Ssal_02035 2.5e-109 314.0 2E0MY@1|root,32W75@2|Bacteria,1VFZQ@1239|Firmicutes,4HKWR@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF3013) XK27_03960 - - - - - - - - - - - DUF3013 BJHFPPGC_01194 904306.HMPREF9192_0255 1.53e-97 284.0 COG0494@1|root,COG0494@2|Bacteria,1V8D5@1239|Firmicutes,4HJKW@91061|Bacilli 91061|Bacilli L NUDIX domain - - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX BJHFPPGC_01195 1046629.Ssal_02032 1.67e-221 611.0 COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,4HAMF@91061|Bacilli 91061|Bacilli J Ribosomal protein L11 methyltransferase prmA - - ko:K02687 - - - - ko00000,ko01000,ko03009 - - - PrmA BJHFPPGC_01196 1046629.Ssal_02031 6.54e-168 470.0 COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,4HH8P@91061|Bacilli 91061|Bacilli J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit rsmE GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 ko:K09761 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_RNA BJHFPPGC_01197 1046629.Ssal_02030 0.0 1545.0 COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,4HB9S@91061|Bacilli 91061|Bacilli F Belongs to the 5'-nucleotidase family cpdB - 3.1.3.6,3.1.4.16 ko:K01119 ko00230,ko00240,map00230,map00240 - R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135 RC00078,RC00296 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Gram_pos_anchor,Metallophos,SLH BJHFPPGC_01198 1046629.Ssal_02029 6.05e-109 313.0 COG1780@1|root,COG1780@2|Bacteria,1V71V@1239|Firmicutes,4HIW7@91061|Bacilli 91061|Bacilli F Belongs to the NrdI family nrdI - - ko:K03647 - - - - ko00000 - - - Flavodoxin_NdrI BJHFPPGC_01199 1046629.Ssal_02028 0.0 1448.0 COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,4HBX7@91061|Bacilli 91061|Bacilli KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K00951 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - iYO844.BSU27600 ACT_4,HD_4,RelA_SpoT,TGS BJHFPPGC_01200 1046629.Ssal_02026 6.49e-94 275.0 COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,4HINN@91061|Bacilli 91061|Bacilli J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality dtd GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - ko:K07560 - - - - ko00000,ko01000,ko03016 - - - Tyr_Deacylase BJHFPPGC_01201 1046629.Ssal_02025 0.0 1784.0 COG5297@1|root,COG5297@2|Bacteria,1TS2G@1239|Firmicutes,4HF5J@91061|Bacilli 91061|Bacilli G Glycosyl hydrolase family 66 dex - 3.2.1.11 ko:K05988 ko00500,map00500 - R11309 - ko00000,ko00001,ko01000 - GH66 - CBM_35,Glyco_hydro_66,Gram_pos_anchor,SLH BJHFPPGC_01202 1046629.Ssal_02023 2.24e-301 822.0 COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,4H9NK@91061|Bacilli 91061|Bacilli E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA ilvA GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_dehydrat_C BJHFPPGC_01203 904306.HMPREF9192_0243 1.46e-145 410.0 COG0242@1|root,COG0242@2|Bacteria,1V5C6@1239|Firmicutes,4HGUI@91061|Bacilli 91061|Bacilli J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase BJHFPPGC_01204 1046629.Ssal_02021 3.25e-137 389.0 COG0664@1|root,COG0664@2|Bacteria,1V2AH@1239|Firmicutes,4HFNC@91061|Bacilli 91061|Bacilli K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - - - - - - - - - - HTH_Crp_2,cNMP_binding BJHFPPGC_01205 1046629.Ssal_02020 1.6e-228 635.0 COG2807@1|root,COG2807@2|Bacteria,1TSM5@1239|Firmicutes,4HF98@91061|Bacilli 91061|Bacilli P Major Facilitator XK27_00055 - - - - - - - - - - - MFS_1 BJHFPPGC_01206 435842.HMPREF0848_01487 1.74e-57 178.0 COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,4HKE9@91061|Bacilli 91061|Bacilli J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome rpsO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02956 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S15 BJHFPPGC_01207 1046629.Ssal_02018 4.84e-122 350.0 COG4767@1|root,COG4767@2|Bacteria,1VM0K@1239|Firmicutes,4HVBZ@91061|Bacilli 91061|Bacilli V VanZ like family - - - - - - - - - - - - VanZ BJHFPPGC_01208 1046629.Ssal_02017 9.74e-306 869.0 COG1196@1|root,COG1196@2|Bacteria,1VXI0@1239|Firmicutes,4HMHC@91061|Bacilli 91061|Bacilli D nuclear chromosome segregation - - - - - - - - - - - - Gram_pos_anchor BJHFPPGC_01211 888833.HMPREF9421_1812 6.47e-156 440.0 COG3279@1|root,COG3279@2|Bacteria,1V86T@1239|Firmicutes,4HJQ7@91061|Bacilli 91061|Bacilli KT response regulator agrA - - ko:K07707 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg BJHFPPGC_01212 888833.HMPREF9421_1813 9.49e-185 529.0 COG3290@1|root,COG3290@2|Bacteria,1UYTM@1239|Firmicutes,4HH4V@91061|Bacilli 91061|Bacilli T ATPase histidine kinase DNA gyrase B HSP90 domain protein agrC - 2.7.13.3 ko:K07706 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c_5 BJHFPPGC_01213 1214217.ALNF01000050_gene803 2.66e-66 212.0 2CSEJ@1|root,30BZJ@2|Bacteria,1U8XF@1239|Firmicutes,4IIW4@91061|Bacilli,1WSHD@1307|Streptococcus suis 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_01216 176090.SSIN_1052 1.43e-165 468.0 COG1131@1|root,COG1131@2|Bacteria,1TPBQ@1239|Firmicutes,4HEPD@91061|Bacilli 91061|Bacilli V ABC transporter - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran BJHFPPGC_01217 391295.SSU05_0046 6.14e-61 199.0 2CSEJ@1|root,30BZN@2|Bacteria,1U8XJ@1239|Firmicutes,4IIWA@91061|Bacilli,1WSIT@1307|Streptococcus suis 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_01218 1046629.Ssal_02016 4.26e-168 470.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli 91061|Bacilli E abc transporter atp-binding protein glnQ - - ko:K17076 ko02010,map02010 M00589 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3.20 - - ABC_tran BJHFPPGC_01219 1046629.Ssal_02015 0.0 953.0 COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,1TPM3@1239|Firmicutes,4HAS2@91061|Bacilli 91061|Bacilli P ABC transporter XK27_05795 - - ko:K17073,ko:K17074 ko02010,map02010 M00589 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.20 - - BPD_transp_1,SBP_bac_3 BJHFPPGC_01220 1046629.Ssal_02014 1.75e-195 543.0 COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,4HB0M@91061|Bacilli 91061|Bacilli V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin uppP - 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - BacA BJHFPPGC_01222 1046629.Ssal_02012 7.31e-166 465.0 COG4862@1|root,COG4862@2|Bacteria,1UZ7D@1239|Firmicutes,4HID6@91061|Bacilli 91061|Bacilli NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis mecA GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K16511 - - - - ko00000 - - - MecA BJHFPPGC_01223 1046629.Ssal_02011 1.81e-241 667.0 COG0472@1|root,COG0472@2|Bacteria,1TP9V@1239|Firmicutes,4H9KT@91061|Bacilli 91061|Bacilli M transferase tagO GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914 2.7.8.33,2.7.8.35 ko:K02851 - - R08856 RC00002 ko00000,ko01000,ko01003,ko01005 - - - Glycos_transf_4 BJHFPPGC_01224 1046629.Ssal_02010 1.65e-176 493.0 COG0396@1|root,COG0396@2|Bacteria,1TQ98@1239|Firmicutes,4HAD9@91061|Bacilli 91061|Bacilli O ABC-type transport system involved in Fe-S cluster assembly, ATPase component sufC - - ko:K09013 - - - - ko00000,ko02000 - - - ABC_tran BJHFPPGC_01225 904306.HMPREF9192_0233 4.66e-296 808.0 COG0719@1|root,COG0719@2|Bacteria,1TRT0@1239|Firmicutes,4HB6W@91061|Bacilli 91061|Bacilli O assembly protein SufD sufD - - ko:K07033,ko:K09015 - - - - ko00000 - - - UPF0051 BJHFPPGC_01226 1046629.Ssal_02008 3.53e-295 805.0 COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,4HA6Z@91061|Bacilli 91061|Bacilli E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine sufS - 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 - R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 - - - Aminotran_5 BJHFPPGC_01227 904306.HMPREF9192_0231 1.74e-96 281.0 COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,4HIJ0@91061|Bacilli 91061|Bacilli C SUF system FeS assembly protein, NifU family nifU GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564 - ko:K04488 - - - - ko00000 - - - NifU_N BJHFPPGC_01228 904306.HMPREF9192_0230 0.0 945.0 COG0719@1|root,COG0719@2|Bacteria,1TQ21@1239|Firmicutes,4HA1Z@91061|Bacilli 91061|Bacilli O assembly protein SufB sufB - - ko:K07033,ko:K09014 - - - - ko00000 - - - UPF0051 BJHFPPGC_01229 1123311.KB904471_gene1168 3.04e-35 124.0 2DCPN@1|root,2ZEV1@2|Bacteria,1W24H@1239|Firmicutes,4HZKX@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_01230 1046629.Ssal_01995 1.34e-201 558.0 COG1281@1|root,COG1281@2|Bacteria,1TRCH@1239|Firmicutes,4HAFR@91061|Bacilli 91061|Bacilli O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress hslO - - ko:K04083 - - - - ko00000,ko03110 - - - HSP33 BJHFPPGC_01231 435842.HMPREF0848_01508 2.41e-233 643.0 COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,4HA9K@91061|Bacilli 91061|Bacilli J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines dus - - ko:K05540 - - - - ko00000,ko01000,ko03016 - - - Dus BJHFPPGC_01232 1046629.Ssal_01993 2.91e-91 268.0 COG1846@1|root,COG1846@2|Bacteria,1VXZT@1239|Firmicutes,4HXMU@91061|Bacilli 91061|Bacilli K transcriptional adcR - - - - - - - - - - - HTH_27,MarR BJHFPPGC_01233 1046629.Ssal_01992 2.06e-174 485.0 COG1121@1|root,COG1121@2|Bacteria,1TQ68@1239|Firmicutes,4HAZI@91061|Bacilli 91061|Bacilli P ABC transporter, ATP-binding protein adcC - - ko:K02074,ko:K09817 ko02010,map02010 M00242,M00244 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - iYO844.BSU02860 ABC_tran BJHFPPGC_01234 904306.HMPREF9192_0223 8.57e-164 461.0 COG1108@1|root,COG1108@2|Bacteria,1TR79@1239|Firmicutes,4HC3C@91061|Bacilli 91061|Bacilli P ABC transporter (Permease adcB GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0010035,GO:0010038,GO:0010043,GO:0016020,GO:0042221,GO:0044464,GO:0050896,GO:0071944 - ko:K09816 ko02010,map02010 M00242 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.3,3.A.1.15.5 - - ABC-3 BJHFPPGC_01235 1046629.Ssal_01990 1.75e-201 561.0 COG0679@1|root,COG0679@2|Bacteria,1UY4N@1239|Firmicutes,4HB48@91061|Bacilli 91061|Bacilli S Transporter, auxin efflux carrier (AEC) family protein mleP2 - - ko:K07088 - - - - ko00000 - - - Mem_trans BJHFPPGC_01236 1046629.Ssal_01989 0.0 1335.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TPJ8@1239|Firmicutes,4HA8X@91061|Bacilli 91061|Bacilli G pts system ptsG - 2.7.1.208 ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00270,M00272,M00303,M00806 R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.1.11,4.A.1.1.12 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC BJHFPPGC_01237 1046629.Ssal_01988 9.65e-201 556.0 COG3568@1|root,COG3568@2|Bacteria,1TQZG@1239|Firmicutes,4HGS5@91061|Bacilli 91061|Bacilli L Endonuclease/Exonuclease/phosphatase family rgfB - 3.1.3.90 ko:K06896 ko00500,map00500 - R10486 RC00017 ko00000,ko00001,ko01000 - - - Exo_endo_phos BJHFPPGC_01238 1046629.Ssal_01987 0.0 887.0 COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,4H9VI@91061|Bacilli 91061|Bacilli G Belongs to the GPI family pgi GO:0003674,GO:0003824,GO:0004347,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI BJHFPPGC_01239 435842.HMPREF0848_01516 5.16e-191 532.0 COG1396@1|root,COG1396@2|Bacteria,1UZI0@1239|Firmicutes,4HC2C@91061|Bacilli 91061|Bacilli K Transcriptional activator, Rgg GadR MutR family - - - ko:K20373,ko:K20374 ko02024,map02024 - - - ko00000,ko00001,ko03000 - - - HTH_3 BJHFPPGC_01240 1046629.Ssal_01985 0.0 924.0 COG1132@1|root,COG1132@2|Bacteria,1TSRV@1239|Firmicutes,4HCIZ@91061|Bacilli 91061|Bacilli V ABC transporter - - - ko:K06147,ko:K06148 - - - - ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran BJHFPPGC_01241 1046629.Ssal_01984 2.37e-161 452.0 COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,4H9WJ@91061|Bacilli 91061|Bacilli K transcriptional regulatory protein yeeN GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Transcrip_reg BJHFPPGC_01242 904306.HMPREF9192_0217 6.02e-62 191.0 COG1862@1|root,COG1862@2|Bacteria 2|Bacteria U protein transport yajC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - YajC BJHFPPGC_01243 1046629.Ssal_01982 3.56e-182 506.0 COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,4HA37@91061|Bacilli 91061|Bacilli H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids uppS GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf BJHFPPGC_01244 1046629.Ssal_01981 7.14e-185 514.0 COG4589@1|root,COG4589@2|Bacteria,1TT0Q@1239|Firmicutes,4HAMN@91061|Bacilli 91061|Bacilli S Belongs to the CDS family cdsA GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06255 CTP_transf_1 BJHFPPGC_01245 1046629.Ssal_01980 1.82e-293 802.0 COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,4HAQ5@91061|Bacilli 91061|Bacilli M zinc metalloprotease rseP - - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ_2,Peptidase_M50 BJHFPPGC_01246 1046629.Ssal_01979 0.0 1195.0 COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,4H9NN@91061|Bacilli 91061|Bacilli J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS proS - 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA_edit BJHFPPGC_01247 1046629.Ssal_01978 0.0 1148.0 COG2984@1|root,COG4120@1|root,COG2984@2|Bacteria,COG4120@2|Bacteria,1TPB0@1239|Firmicutes,4HESK@91061|Bacilli 91061|Bacilli S ABC transporter XK27_00665 - - ko:K01989,ko:K05832 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind BJHFPPGC_01248 1046629.Ssal_01977 8.63e-183 509.0 COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,4HCHC@91061|Bacilli 91061|Bacilli S abc transporter atp-binding protein cmpC - - ko:K05833 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_tran BJHFPPGC_01249 1046629.Ssal_01975 7.72e-57 177.0 COG0234@1|root,COG0234@2|Bacteria 2|Bacteria O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0032991,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051704,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:0101031,GO:1903506,GO:1990220,GO:2000112,GO:2001141 - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 BJHFPPGC_01250 1046629.Ssal_01974 0.0 990.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,4HA38@91061|Bacilli 91061|Bacilli O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL GO:0001817,GO:0001819,GO:0001871,GO:0002791,GO:0002793,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009986,GO:0009987,GO:0016465,GO:0030246,GO:0030247,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044764,GO:0046812,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051082,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051704,GO:0061077,GO:0065007,GO:0070201,GO:0090087,GO:0098630,GO:0098743,GO:0101031,GO:1903530,GO:1903532,GO:1904951,GO:1990220,GO:2000482,GO:2000484,GO:2001065 - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 BJHFPPGC_01252 435842.HMPREF0848_01529 5.73e-58 180.0 2C0H5@1|root,2ZRTJ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DUF2752 BJHFPPGC_01253 904306.HMPREF9192_0207 9.35e-74 221.0 COG2314@1|root,COG2314@2|Bacteria,1VKEZ@1239|Firmicutes,4HS74@91061|Bacilli 91061|Bacilli S TM2 domain WQ51_06355 - - - - - - - - - - - TM2 BJHFPPGC_01254 1046629.Ssal_01970 2.51e-202 560.0 COG0564@1|root,COG0564@2|Bacteria,1TSM6@1239|Firmicutes,4HA7M@91061|Bacilli 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil rluA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2 BJHFPPGC_01255 904306.HMPREF9192_0205 0.0 1479.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli 91061|Bacilli M penicillin-binding protein pbp2A - 2.4.1.129,3.4.16.4 ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase BJHFPPGC_01256 904306.HMPREF9192_0204 1.05e-33 115.0 COG0690@1|root,COG0690@2|Bacteria,1W4QH@1239|Firmicutes 1239|Firmicutes U Belongs to the SecE SEC61-gamma family secE - - ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecE BJHFPPGC_01257 1046629.Ssal_01967 2.8e-124 354.0 COG0250@1|root,COG0250@2|Bacteria,1TR3P@1239|Firmicutes,4HAJA@91061|Bacilli 91061|Bacilli K Participates in transcription elongation, termination and antitermination nusG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K02601 - - - - ko00000,ko03009,ko03021 - - - KOW,NusG BJHFPPGC_01258 264199.stu0216 9.07e-92 270.0 COG0671@1|root,COG0671@2|Bacteria 2|Bacteria I phosphatidate phosphatase activity - - 3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 ko:K01096,ko:K19302 ko00550,ko00564,ko01100,map00550,map00564,map01100 - R02029,R05627 RC00002,RC00017 ko00000,ko00001,ko01000,ko01011 - - - PAP2 BJHFPPGC_01259 904306.HMPREF9192_0201 1.23e-183 511.0 COG0561@1|root,COG0561@2|Bacteria,1TR16@1239|Firmicutes,4HK1G@91061|Bacilli 91061|Bacilli S Sucrose-6F-phosphate phosphohydrolase cof - - - - - - - - - - - Hydrolase_3 BJHFPPGC_01260 1046629.Ssal_01963 9.27e-172 480.0 COG1349@1|root,COG1349@2|Bacteria,1V6VV@1239|Firmicutes,4HK1E@91061|Bacilli 91061|Bacilli K transcriptional regulator (DeoR family) - - - ko:K22103 - - - - ko00000,ko03000 - - - DeoRC,HTH_DeoR BJHFPPGC_01261 435842.HMPREF0848_01539 0.0 1687.0 COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,4HAG1@91061|Bacilli 91061|Bacilli J Belongs to the class-I aminoacyl-tRNA synthetase family leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 BJHFPPGC_01262 1046629.Ssal_01960 8.75e-94 275.0 COG1846@1|root,COG1846@2|Bacteria,1V1U2@1239|Firmicutes,4HI88@91061|Bacilli 91061|Bacilli K transcriptional napB - - - - - - - - - - - MarR BJHFPPGC_01263 904306.HMPREF9192_0197 1.08e-289 791.0 COG1073@1|root,COG1073@2|Bacteria,1V38K@1239|Firmicutes,4HE7V@91061|Bacilli 91061|Bacilli S COG1073 Hydrolases of the alpha beta superfamily - - - ko:K06889 - - - - ko00000 - - - BAAT_C,Bile_Hydr_Trans BJHFPPGC_01264 904306.HMPREF9192_0196 2e-65 202.0 28NY7@1|root,2ZBVG@2|Bacteria,1V2J3@1239|Firmicutes,4HMY0@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF2992) yjdF3 - - - - - - - - - - - DUF2992 BJHFPPGC_01265 435842.HMPREF0848_01541 1.34e-62 192.0 COG2350@1|root,COG2350@2|Bacteria 2|Bacteria S YCII-related domain - - 3.2.2.21 ko:K03652 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - YCII BJHFPPGC_01266 888049.HMPREF8578_0321 4.78e-69 208.0 COG1733@1|root,COG1733@2|Bacteria 2|Bacteria K regulation of RNA biosynthetic process - - - - - - - - - - - - HxlR BJHFPPGC_01267 435842.HMPREF0848_01543 4.62e-193 537.0 COG1131@1|root,COG1131@2|Bacteria,1V0AH@1239|Firmicutes,4HD15@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein cylA - - ko:K11050 ko02010,map02010 M00298 - - ko00000,ko00001,ko00002,ko02000 3.A.1.130 - - ABC_tran BJHFPPGC_01268 435842.HMPREF0848_01544 1.85e-179 502.0 COG0842@1|root,COG0842@2|Bacteria,1TSH0@1239|Firmicutes,4HFNX@91061|Bacilli 91061|Bacilli V ABC-2 type transporter cylB - - ko:K11051 ko02010,map02010 M00298 - - ko00000,ko00001,ko00002,ko02000 3.A.1.130 - - ABC2_membrane,ABC2_membrane_3 BJHFPPGC_01269 435842.HMPREF0848_01545 1.58e-96 281.0 COG3279@1|root,COG3279@2|Bacteria,1VFKH@1239|Firmicutes,4HQ50@91061|Bacilli 91061|Bacilli K COG3279 Response regulator of the LytR AlgR family - - - ko:K07705 ko02020,map02020 M00492 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR BJHFPPGC_01270 585203.SMSK564_0811 1.56e-40 139.0 2DKBP@1|root,30949@2|Bacteria,1U4EH@1239|Firmicutes,4IE74@91061|Bacilli,2TPSA@28037|Streptococcus mitis 91061|Bacilli S Protein of unknown function (DUF3021) - - - - - - - - - - - - DUF3021 BJHFPPGC_01271 435842.HMPREF0848_01547 1.32e-157 443.0 COG0789@1|root,COG0789@2|Bacteria,1TS6Z@1239|Firmicutes,4HCVW@91061|Bacilli 91061|Bacilli K Transcriptional mta - - ko:K21743 - - - - ko00000,ko03000 - - - MerR_1,TipAS BJHFPPGC_01272 1046629.Ssal_01952 1.82e-155 437.0 COG1136@1|root,COG1136@2|Bacteria,1V50G@1239|Firmicutes,4HIB8@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein - - - - - - - - - - - - ABC_tran BJHFPPGC_01273 1046629.Ssal_01951 2.25e-261 720.0 COG0577@1|root,COG0577@2|Bacteria,1VU6Y@1239|Firmicutes,4HT9M@91061|Bacilli 91061|Bacilli V FtsX-like permease family - - - - - - - - - - - - FtsX BJHFPPGC_01274 1046629.Ssal_01950 0.0 946.0 COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,4HAI4@91061|Bacilli 91061|Bacilli H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP pncB - 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 - R01724 RC00033 ko00000,ko00001,ko01000 - - - NAPRTase BJHFPPGC_01275 904306.HMPREF9192_0172 6.89e-192 533.0 COG0171@1|root,COG0171@2|Bacteria,1TQ38@1239|Firmicutes,4HA2R@91061|Bacilli 91061|Bacilli H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source nadE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5 ko:K01916 ko00760,ko01100,map00760,map01100 M00115 R00189 RC00100 ko00000,ko00001,ko00002,ko01000 - - - NAD_synthase BJHFPPGC_01276 1046629.Ssal_01947 5.55e-95 277.0 COG3152@1|root,COG3152@2|Bacteria,1VDSW@1239|Firmicutes 1239|Firmicutes S Protein of unknown function (DUF805) yhaH - - - - - - - - - - - DUF805 BJHFPPGC_01277 1046629.Ssal_01946 0.0 873.0 COG3579@1|root,COG3579@2|Bacteria,1TRJN@1239|Firmicutes,4HBZ9@91061|Bacilli 91061|Bacilli E aminopeptidase pepC GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006508,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0009056,GO:0009063,GO:0009636,GO:0009987,GO:0016054,GO:0016787,GO:0019538,GO:0019752,GO:0042221,GO:0043170,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0050667,GO:0050896,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.4.22.40 ko:K01372 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C1_2 BJHFPPGC_01278 1046629.Ssal_01944 0.0 1395.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli 91061|Bacilli M penicillin-binding protein ponA GO:0005575,GO:0005576 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase,fn3 BJHFPPGC_01279 1046629.Ssal_01943 2.86e-140 396.0 COG3331@1|root,COG3331@2|Bacteria,1V3S4@1239|Firmicutes,4HGZ7@91061|Bacilli 91061|Bacilli L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation recU GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03700 - - - - ko00000,ko03400 - - - RecU BJHFPPGC_01280 1046629.Ssal_01942 9.9e-121 344.0 COG4474@1|root,COG4474@2|Bacteria,1V5Q7@1239|Firmicutes,4HECZ@91061|Bacilli 91061|Bacilli S Belongs to the UPF0398 family ypsA - - - - - - - - - - - DUF1273 BJHFPPGC_01281 1046629.Ssal_01941 3.26e-65 199.0 COG3599@1|root,COG3599@2|Bacteria,1VEQ4@1239|Firmicutes,4HNP1@91061|Bacilli 91061|Bacilli D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation gpsB - - - - - - - - - - - DivIVA BJHFPPGC_01282 1046629.Ssal_01940 5.28e-284 775.0 COG0116@1|root,COG0116@2|Bacteria,1TP0X@1239|Firmicutes,4HBKY@91061|Bacilli 91061|Bacilli L Belongs to the methyltransferase superfamily ypsC GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 - ko:K07444 - - - - ko00000,ko01000 - - - THUMP,UPF0020 BJHFPPGC_01283 1046629.Ssal_01939 0.0 1046.0 2DB6P@1|root,32TWV@2|Bacteria,1VDPS@1239|Firmicutes,4HK8Y@91061|Bacilli 91061|Bacilli D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning mapZ - - ko:K20073 - - - - ko00000 - - - - BJHFPPGC_01284 1046629.Ssal_01938 0.0 1986.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4HAIF@91061|Bacilli 91061|Bacilli L Superfamily II DNA RNA helicases, SNF2 family' snf - - - - - - - - - - - Helicase_C,SNF2_N,SNF2_assoc,SWIM BJHFPPGC_01285 1214166.ALLG01000002_gene1746 3.69e-27 111.0 2BTGZ@1|root,32NPB@2|Bacteria,1U91J@1239|Firmicutes,4IJ1N@91061|Bacilli,1WTEE@1307|Streptococcus suis 91061|Bacilli - - XK27_11680 - - - - - - - - - - - - BJHFPPGC_01286 1046629.Ssal_01936 0.0 878.0 COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,4HAR4@91061|Bacilli 91061|Bacilli M Belongs to the MurCDEF family murC - 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M BJHFPPGC_01287 1046629.Ssal_01935 5.79e-112 322.0 COG0454@1|root,COG0454@2|Bacteria,1VB76@1239|Firmicutes,4HM71@91061|Bacilli 91061|Bacilli K histone acetyltransferase HPA2 and related acetyltransferases - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 BJHFPPGC_01288 1046629.Ssal_01934 0.0 1126.0 COG1559@1|root,COG1559@2|Bacteria,1TS48@1239|Firmicutes,4HAUV@91061|Bacilli 91061|Bacilli ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation mltG - - ko:K07082 - - - - ko00000 - - - YceG BJHFPPGC_01289 1046629.Ssal_01933 1.17e-100 293.0 COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,4HGZU@91061|Bacilli 91061|Bacilli K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides greA GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - ko:K03624 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N BJHFPPGC_01290 1046629.Ssal_01931 6.93e-208 576.0 COG0706@1|root,COG0706@2|Bacteria,1TSDN@1239|Firmicutes,4HCC8@91061|Bacilli 91061|Bacilli U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins yidC - - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP BJHFPPGC_01291 1046629.Ssal_01930 2.63e-58 180.0 COG1254@1|root,COG1254@2|Bacteria,1VEM9@1239|Firmicutes,4HNN7@91061|Bacilli 91061|Bacilli C Belongs to the acylphosphatase family acyP GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 - R00317,R01421,R01515 RC00043 ko00000,ko00001,ko01000 - - iSB619.SA_RS07020 Acylphosphatase BJHFPPGC_01292 1046629.Ssal_01929 1.27e-164 461.0 COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,4HCF5@91061|Bacilli 91061|Bacilli J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family spoU - - ko:K03437 - - - - ko00000,ko03016 - - - SpoU_methylase,SpoU_sub_bind BJHFPPGC_01293 1046629.Ssal_01928 2.55e-121 345.0 COG1418@1|root,COG1418@2|Bacteria,1V4QX@1239|Firmicutes,4HHW0@91061|Bacilli 91061|Bacilli S HD superfamily hydrolase XK27_09705 - - ko:K06950 - - - - ko00000 - - - HD BJHFPPGC_01294 1046629.Ssal_01927 3.31e-143 406.0 COG0670@1|root,COG0670@2|Bacteria,1V779@1239|Firmicutes,4HIX1@91061|Bacilli 91061|Bacilli S Belongs to the BI1 family ybhL - - ko:K06890 - - - - ko00000 - - - Bax1-I BJHFPPGC_01296 1046629.Ssal_01925 4.75e-309 841.0 COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,4H9XW@91061|Bacilli 91061|Bacilli E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine lysA - 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC BJHFPPGC_01297 1046629.Ssal_01924 7.36e-116 333.0 COG1309@1|root,COG1309@2|Bacteria 2|Bacteria K transcriptional regulator - - - - - - - - - - - - TetR_N BJHFPPGC_01298 1046629.Ssal_01923 2.31e-48 154.0 COG3763@1|root,COG3763@2|Bacteria,1VDSU@1239|Firmicutes,4HM8G@91061|Bacilli 91061|Bacilli S UPF0154 protein - - - ko:K09976 - - - - ko00000 - - - UPF0154 BJHFPPGC_01299 1046629.Ssal_01922 2.4e-191 531.0 COG0796@1|root,COG0796@2|Bacteria,1TPPR@1239|Firmicutes,4HA46@91061|Bacilli 91061|Bacilli M Provides the (R)-glutamate required for cell wall biosynthesis murI GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 3.6.1.66,5.1.1.3 ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 - R00260,R00426,R00720,R01855,R02100,R02720,R03531 RC00002,RC00302 ko00000,ko00001,ko01000,ko01011 - - iYO844.BSU28390 Asp_Glu_race BJHFPPGC_01300 1046629.Ssal_01921 1.19e-229 632.0 COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,4HCP6@91061|Bacilli 91061|Bacilli F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions rdgB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - - Ham1p_like BJHFPPGC_01301 904306.HMPREF9192_0139 1.03e-123 352.0 COG0622@1|root,COG0622@2|Bacteria,1VA0U@1239|Firmicutes,4HM24@91061|Bacilli 91061|Bacilli S Phosphoesterase ysnB GO:0003674,GO:0005488,GO:0008270,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - ko:K07095 - - - - ko00000 - - - Metallophos_2 BJHFPPGC_01302 1046629.Ssal_01919 3.52e-111 319.0 COG0517@1|root,COG0517@2|Bacteria,1VFAB@1239|Firmicutes,4HRWJ@91061|Bacilli 91061|Bacilli S CBS domain ykuL - - - - - - - - - - - CBS BJHFPPGC_01303 1046629.Ssal_01918 1.12e-163 460.0 COG4974@1|root,COG4974@2|Bacteria,1VY7C@1239|Firmicutes,4IT0W@91061|Bacilli 91061|Bacilli L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site xerD - - - - - - - - - - - Phage_int_SAM_1,Phage_integrase BJHFPPGC_01304 904306.HMPREF9192_0136 2.26e-154 435.0 COG1354@1|root,COG1354@2|Bacteria,1V8JV@1239|Firmicutes,4IQZ5@91061|Bacilli 91061|Bacilli D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves scpA - - ko:K05896 - - - - ko00000,ko03036 - - - SMC_ScpA BJHFPPGC_01305 904306.HMPREF9192_0135 3.31e-123 352.0 COG1386@1|root,COG1386@2|Bacteria,1V6HI@1239|Firmicutes,4HIQ0@91061|Bacilli 91061|Bacilli D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves scpB GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K06024 - - - - ko00000,ko03036 - - - SMC_ScpB BJHFPPGC_01306 1046629.Ssal_01915 1.75e-169 473.0 COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,4H9MU@91061|Bacilli 91061|Bacilli J Belongs to the pseudouridine synthase RsuA family rluB - 5.4.99.22 ko:K06178 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 BJHFPPGC_01307 1046629.Ssal_01914 2.01e-19 78.6 COG0759@1|root,COG0759@2|Bacteria 2|Bacteria M Could be involved in insertion of integral membrane proteins into the membrane yidD - - ko:K08998 - - - - ko00000 - - - Haemolytic BJHFPPGC_01308 1046629.Ssal_01912 0.0 902.0 COG0168@1|root,COG0168@2|Bacteria,1TPAF@1239|Firmicutes,4HCWN@91061|Bacilli 91061|Bacilli P Cation transport protein trkH - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH BJHFPPGC_01309 1046629.Ssal_01911 1.82e-310 847.0 COG0569@1|root,COG0569@2|Bacteria,1TPNS@1239|Firmicutes,4HCRM@91061|Bacilli 91061|Bacilli P Potassium transporter peripheral membrane component trkA - - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N BJHFPPGC_01310 1046629.Ssal_01910 1.86e-124 353.0 COG0219@1|root,COG0219@2|Bacteria,1V3GW@1239|Firmicutes,4HFNY@91061|Bacilli 91061|Bacilli J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily cspR - 2.1.1.207 ko:K03216 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase BJHFPPGC_01311 264199.stu0268 5.63e-117 337.0 COG3601@1|root,COG3601@2|Bacteria,1V4BW@1239|Firmicutes,4HHFT@91061|Bacilli 91061|Bacilli U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins ribU GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - - - - - - - - - - ECF_trnsprt BJHFPPGC_01312 264199.stu0269 2.14e-128 367.0 COG0671@1|root,COG0671@2|Bacteria,1VF2U@1239|Firmicutes,4HNXR@91061|Bacilli 91061|Bacilli I Membrane-associated phospholipid phosphatase yodM - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2 BJHFPPGC_01313 264199.stu0270 1.01e-197 550.0 COG1396@1|root,COG1396@2|Bacteria 2|Bacteria K sequence-specific DNA binding - - - ko:K20342,ko:K20480 ko02024,map02024 - - - ko00000,ko00001,ko03000 - - - HTH_19,HTH_3 BJHFPPGC_01314 1046629.Ssal_01906 0.0 1287.0 COG2274@1|root,COG2274@2|Bacteria,1V77J@1239|Firmicutes,4HAX2@91061|Bacilli 91061|Bacilli V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain comA - - ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 - - - ko00000,ko00001,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.112,3.A.1.21 - - ABC_membrane,ABC_tran,Peptidase_C39 BJHFPPGC_01315 1046629.Ssal_01905 6.09e-70 211.0 COG3152@1|root,COG3152@2|Bacteria 2|Bacteria L Membrane yhaI - - - - - - - - - - - DUF805 BJHFPPGC_01316 1046629.Ssal_01904 6.04e-307 840.0 2E26M@1|root,32XD2@2|Bacteria,1VCM1@1239|Firmicutes 1239|Firmicutes S Domain of unknown function (DUF4173) - - - - - - - - - - - - DUF4173 BJHFPPGC_01317 1046629.Ssal_01903 2.16e-124 353.0 2DC0F@1|root,2ZC7C@2|Bacteria,1UPV2@1239|Firmicutes,4IVBC@91061|Bacilli 91061|Bacilli S AmiS/UreI family transporter ureI - - ko:K03191 ko05120,map05120 - - - ko00000,ko00001,ko02000 1.A.29.1.3,1.A.29.1.4,1.A.29.1.5 - - AmiS_UreI BJHFPPGC_01318 264199.stu0281 1.02e-61 189.0 COG0831@1|root,COG0831@2|Bacteria,1V7GU@1239|Firmicutes,4HIJS@91061|Bacilli 91061|Bacilli E Belongs to the urease gamma subunit family ureA - 3.5.1.5 ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 - R00131 RC02798,RC02806 ko00000,ko00001,ko01000 - - iSB619.SA_RS11965,iYO844.BSU36660 Urease_gamma BJHFPPGC_01319 1046629.Ssal_01901 3.78e-72 216.0 COG0832@1|root,COG0832@2|Bacteria,1VAIA@1239|Firmicutes,4HM0I@91061|Bacilli 91061|Bacilli E Belongs to the urease beta subunit family ureB - 3.5.1.5 ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 - R00131 RC02798,RC02806 ko00000,ko00001,ko01000 - - - Urease_beta BJHFPPGC_01320 904306.HMPREF9192_0116 0.0 1155.0 COG0804@1|root,COG0804@2|Bacteria,1TPQP@1239|Firmicutes,4HBTS@91061|Bacilli 91061|Bacilli E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family ureC - 3.5.1.5 ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 - R00131 RC02798,RC02806 ko00000,ko00001,ko01000 - - - Amidohydro_1,Urease_alpha BJHFPPGC_01321 1046629.Ssal_01898 2.74e-101 293.0 COG2371@1|root,COG2371@2|Bacteria 2|Bacteria O enzyme active site formation ureE GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K03187 - - - - ko00000 - - - UreE_C,UreE_N BJHFPPGC_01322 1046629.Ssal_01897 1.23e-167 468.0 COG0830@1|root,COG0830@2|Bacteria,1V2H0@1239|Firmicutes,4HHW3@91061|Bacilli 91061|Bacilli O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter ureF - - ko:K03188 - - - - ko00000 - - - UreF BJHFPPGC_01323 1046629.Ssal_01896 4.71e-142 401.0 COG0378@1|root,COG0378@2|Bacteria,1TS00@1239|Firmicutes,4HC5C@91061|Bacilli 91061|Bacilli KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG ureG - - ko:K03189 - - - - ko00000 - - - cobW BJHFPPGC_01324 264199.stu0287 5.5e-201 556.0 COG0829@1|root,COG0829@2|Bacteria,1TVM2@1239|Firmicutes,4HCED@91061|Bacilli 91061|Bacilli O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter ureD - - ko:K03190 - - - - ko00000 - - - UreD BJHFPPGC_01325 1046629.Ssal_01894 1.18e-225 622.0 COG0310@1|root,COG0310@2|Bacteria,1TPEN@1239|Firmicutes,4HARY@91061|Bacilli 91061|Bacilli P PDGLE domain cbiM - - ko:K02007 ko02010,map02010 M00245,M00246 - - ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23 - - CbiM,PDGLE BJHFPPGC_01326 1046629.Ssal_01892 6.8e-176 491.0 COG0619@1|root,COG0619@2|Bacteria,1V7YC@1239|Firmicutes 1239|Firmicutes P cobalt transport protein nikQ - - ko:K02008 ko02010,map02010 M00245,M00246 - - ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23 - - CbiQ BJHFPPGC_01327 1046629.Ssal_01891 9.38e-168 469.0 COG1122@1|root,COG1122@2|Bacteria,1V16T@1239|Firmicutes,4HI15@91061|Bacilli 91061|Bacilli P ABC transporter - - - ko:K02006 ko02010,map02010 M00245,M00246 - - ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23 - - ABC_tran BJHFPPGC_01328 1046629.Ssal_01890 1.21e-185 518.0 COG0834@1|root,COG0834@2|Bacteria,1VWFY@1239|Firmicutes,4HW2H@91061|Bacilli 91061|Bacilli ET ABC transporter substrate-binding protein - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 BJHFPPGC_01329 1046629.Ssal_01889 2e-209 579.0 COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,4HCTA@91061|Bacilli 91061|Bacilli M Belongs to the NlpA lipoprotein family metQ - - ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 BJHFPPGC_01330 1046629.Ssal_01888 0.0 915.0 COG0624@1|root,COG0624@2|Bacteria,1TP2D@1239|Firmicutes,4HB9G@91061|Bacilli 91061|Bacilli E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases dapE - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 BJHFPPGC_01331 1046629.Ssal_01887 2.32e-238 657.0 COG1135@1|root,COG1135@2|Bacteria,1TPPN@1239|Firmicutes,4H9VX@91061|Bacilli 91061|Bacilli P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system metN - - ko:K02071 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - ABC_tran,NIL BJHFPPGC_01332 1046629.Ssal_01886 1.27e-152 430.0 COG2011@1|root,COG2011@2|Bacteria,1V0GE@1239|Firmicutes,4HFMB@91061|Bacilli 91061|Bacilli P ABC transporter (Permease metI - - ko:K02072 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - BPD_transp_1 BJHFPPGC_01333 1046629.Ssal_01885 6.96e-266 731.0 COG3633@1|root,COG3633@2|Bacteria,1TPD2@1239|Firmicutes,4HBEC@91061|Bacilli 91061|Bacilli E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) sstT - - ko:K07862 - - - - ko00000,ko02000 2.A.23.4 - - SDF BJHFPPGC_01334 322159.STER_0345 5.7e-200 554.0 COG1912@1|root,COG1912@2|Bacteria,1TSR3@1239|Firmicutes,4HAW6@91061|Bacilli 91061|Bacilli S S-adenosyl-l-methionine hydroxide adenosyltransferase ilvH - - - - - - - - - - - SAM_adeno_trans BJHFPPGC_01335 1046629.Ssal_01883 8.98e-122 348.0 COG4720@1|root,COG4720@2|Bacteria,1V1GT@1239|Firmicutes,4HGAE@91061|Bacilli 91061|Bacilli S UPF0397 protein - - - ko:K16924 - M00582 - - ko00000,ko00002,ko02000 3.A.1.29 - - ECF-ribofla_trS BJHFPPGC_01336 1046629.Ssal_01882 0.0 1059.0 COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4HAJM@91061|Bacilli 91061|Bacilli P abc transporter atp-binding protein ykoD GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085 - ko:K16786,ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran,DUF3744 BJHFPPGC_01337 1046629.Ssal_01881 7.98e-188 523.0 COG0619@1|root,COG0619@2|Bacteria,1TPMV@1239|Firmicutes,4HBTW@91061|Bacilli 91061|Bacilli P cobalt transport cbiQ - - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - iSB619.SA_RS14165 CbiQ BJHFPPGC_01338 1046629.Ssal_01880 6.09e-152 427.0 COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,4HBPH@91061|Bacilli 91061|Bacilli P COG0569 K transport systems, NAD-binding component ktrA - - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N BJHFPPGC_01339 1046629.Ssal_01879 1.59e-297 815.0 COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,4H9ME@91061|Bacilli 91061|Bacilli P COG0168 Trk-type K transport systems, membrane components ktrB - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH BJHFPPGC_01340 1046629.Ssal_01878 1.38e-164 461.0 COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,4HAAZ@91061|Bacilli 91061|Bacilli J Ribosomal RNA small subunit methyltransferase G rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 - - - - ko00000,ko01000,ko03009,ko03036 - - - GidB BJHFPPGC_01341 1046629.Ssal_01877 5.42e-117 335.0 COG1399@1|root,COG1399@2|Bacteria,1VB08@1239|Firmicutes,4HME9@91061|Bacilli 91061|Bacilli K metal-binding, possibly nucleic acid-binding protein ylbN - - ko:K07040 - - - - ko00000 - - - DUF177 BJHFPPGC_01342 435842.HMPREF0848_01620 1.62e-159 447.0 COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,4H9NE@91061|Bacilli 91061|Bacilli T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain csrR - - - - - - - - - - - Response_reg,Trans_reg_C BJHFPPGC_01343 1046629.Ssal_01875 0.0 961.0 COG0642@1|root,COG2205@2|Bacteria,1UHQC@1239|Firmicutes,4HWKS@91061|Bacilli 91061|Bacilli T Histidine kinase covS - - - - - - - - - - - HAMP,HATPase_c,HisKA BJHFPPGC_01344 1046629.Ssal_01874 5.84e-105 303.0 COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,4HGXA@91061|Bacilli 91061|Bacilli K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes nrdR - - ko:K07738 - - - - ko00000,ko03000 - - - ATP-cone BJHFPPGC_01345 1046629.Ssal_01873 4.21e-266 730.0 COG3611@1|root,COG3611@2|Bacteria 2|Bacteria L Replication initiation and membrane attachment dnaB - - ko:K03346 - - - - ko00000,ko03032 - - - DnaB_2 BJHFPPGC_01346 1046629.Ssal_01872 1.47e-211 585.0 COG1484@1|root,COG1484@2|Bacteria,1TPZX@1239|Firmicutes,4HABS@91061|Bacilli 91061|Bacilli L Primosomal protein DnaI dnaI GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - ko:K11144 - - - - ko00000,ko03032 - - - DnaI_N,IstB_IS21 BJHFPPGC_01347 1046629.Ssal_01871 4.15e-314 855.0 COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,4HAJ6@91061|Bacilli 91061|Bacilli S GTPase that plays an essential role in the late steps of ribosome biogenesis der - - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 BJHFPPGC_01348 1046629.Ssal_01870 5.84e-134 381.0 2CH4S@1|root,32S58@2|Bacteria,1VC9V@1239|Firmicutes,4HNHW@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_01349 1046629.Ssal_01869 4.62e-296 809.0 COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,4H9Y4@91061|Bacilli 91061|Bacilli J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS - 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b BJHFPPGC_01350 904306.HMPREF9192_0083 3.08e-81 241.0 COG4687@1|root,COG4687@2|Bacteria,1VF36@1239|Firmicutes,4HPYI@91061|Bacilli 91061|Bacilli S protein conserved in bacteria manO - - - - - - - - - - - DUF956 BJHFPPGC_01351 1046629.Ssal_01867 2.02e-215 595.0 COG3716@1|root,COG3716@2|Bacteria,1TQA3@1239|Firmicutes,4HA3K@91061|Bacilli 91061|Bacilli G PTS system mannose fructose sorbose family IID component manN - - ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EIID-AGA BJHFPPGC_01352 904306.HMPREF9192_0081 2.04e-167 471.0 COG3715@1|root,COG3715@2|Bacteria,1TPKK@1239|Firmicutes,4H9QI@91061|Bacilli 91061|Bacilli G pts system manM - - ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 M00276,M00277 R02630,R08366 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1,4.A.6.1.4 - - EII-Sor BJHFPPGC_01353 1046629.Ssal_01865 1.39e-231 638.0 COG2893@1|root,COG3444@1|root,COG2893@2|Bacteria,COG3444@2|Bacteria,1TQJ4@1239|Firmicutes,4H9Z8@91061|Bacilli 91061|Bacilli G pts system manL - 2.7.1.191,2.7.1.202 ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 M00273,M00276 R02630,R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1,4.A.6.1 - - EIIA-man,PTSIIB_sorb BJHFPPGC_01354 1046629.Ssal_01864 4.66e-87 256.0 COG4687@1|root,COG4687@2|Bacteria,1V6KV@1239|Firmicutes 1239|Firmicutes S Protein conserved in bacteria manO - - - - - - - - - - - DUF956 BJHFPPGC_01355 1046629.Ssal_01863 2.24e-208 577.0 COG3716@1|root,COG3716@2|Bacteria,1TQA3@1239|Firmicutes,4HA3K@91061|Bacilli 91061|Bacilli G PTS system mannose fructose sorbose family IID component manN - - ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EIID-AGA BJHFPPGC_01356 1046629.Ssal_01862 6.45e-173 484.0 COG3715@1|root,COG3715@2|Bacteria,1TPKK@1239|Firmicutes,4H9QI@91061|Bacilli 91061|Bacilli G pts system manM - - ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 M00276,M00277 R02630,R08366 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1,4.A.6.1.4 - - EII-Sor BJHFPPGC_01357 1046629.Ssal_01861 9.97e-223 616.0 COG2893@1|root,COG3444@1|root,COG2893@2|Bacteria,COG3444@2|Bacteria,1TQJ4@1239|Firmicutes,4H9Z8@91061|Bacilli 91061|Bacilli G pts system manX - 2.7.1.191,2.7.1.202 ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 M00273,M00276 R02630,R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1,4.A.6.1 - - EIIA-man,PTSIIB_sorb BJHFPPGC_01358 264199.stu0334 1.63e-175 489.0 COG1878@1|root,COG1878@2|Bacteria,1TRBQ@1239|Firmicutes,4HCAB@91061|Bacilli 91061|Bacilli S Metal-dependent hydrolase XK27_00940 - 3.5.1.9 ko:K07130 ko00380,ko00630,ko01100,map00380,map00630,map01100 M00038 R00988,R01959,R04911 RC00263,RC00323 ko00000,ko00001,ko00002,ko01000 - - - Cyclase BJHFPPGC_01359 1046629.Ssal_01859 5.08e-197 545.0 COG0561@1|root,COG0561@2|Bacteria,1TREF@1239|Firmicutes,4H9Y9@91061|Bacilli 91061|Bacilli S hydrolases of the HAD superfamily yitU - 3.1.3.104 ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R07280 RC00017 ko00000,ko00001,ko00002,ko01000 - - - Hydrolase_3 BJHFPPGC_01360 1046629.Ssal_01858 7.03e-316 863.0 COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,4HANG@91061|Bacilli 91061|Bacilli S permease XK27_07275 - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - - Xan_ur_permease BJHFPPGC_01361 1046629.Ssal_01857 1.79e-100 291.0 COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,4HIIF@91061|Bacilli 91061|Bacilli M ATPase or kinase ydiB GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - ko:K06925 - - - - ko00000,ko03016 - - - TsaE BJHFPPGC_01362 1046629.Ssal_01856 2.61e-117 336.0 COG1247@1|root,COG1247@2|Bacteria 2|Bacteria M phosphinothricin N-acetyltransferase activity XK27_05885 - 2.3.1.82 ko:K18816 - - - - br01600,ko00000,ko01000,ko01504 - - - Acetyltransf_1 BJHFPPGC_01363 1046629.Ssal_01855 9.46e-267 734.0 COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,4HA09@91061|Bacilli 91061|Bacilli K Transcriptional brpA - - - - - - - - - - - LytR_cpsA_psr BJHFPPGC_01364 1046629.Ssal_01854 1.75e-105 305.0 COG0779@1|root,COG0779@2|Bacteria,1V6KT@1239|Firmicutes,4HH88@91061|Bacilli 91061|Bacilli S Required for maturation of 30S ribosomal subunits rimP GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K09748 - - - - ko00000,ko03009 - - - DUF150,DUF150_C BJHFPPGC_01365 1046629.Ssal_01853 1.99e-251 694.0 COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,4HA7F@91061|Bacilli 91061|Bacilli K Participates in both transcription termination and antitermination nusA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - KH_5,NusA_N,S1 BJHFPPGC_01366 904306.HMPREF9192_0067 9.2e-64 194.0 COG2740@1|root,COG2740@2|Bacteria,1VEJS@1239|Firmicutes,4HKBY@91061|Bacilli 91061|Bacilli K Nucleic-acid-binding protein implicated in transcription termination ylxR - - ko:K07742 - - - - ko00000 - - - DUF448 BJHFPPGC_01367 1046629.Ssal_01850 1.66e-56 176.0 COG1358@1|root,COG1358@2|Bacteria,1VEYG@1239|Firmicutes 1239|Firmicutes J ribosomal protein ylxQ - - - - - - - - - - - Ribosomal_L7Ae BJHFPPGC_01368 1046629.Ssal_01848 0.0 1323.0 COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,4HA8S@91061|Bacilli 91061|Bacilli J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,IF-2,IF2_N BJHFPPGC_01369 1046629.Ssal_01846 1.15e-75 226.0 COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,4HII1@91061|Bacilli 91061|Bacilli J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA rbfA - - ko:K02834 - - - - ko00000,ko03009 - - - RBFA BJHFPPGC_01370 1046629.Ssal_01845 6.53e-127 361.0 COG1611@1|root,COG1611@2|Bacteria,1UKED@1239|Firmicutes,4HGSU@91061|Bacilli 91061|Bacilli S Belongs to the LOG family - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox BJHFPPGC_01371 1046629.Ssal_01844 0.0 926.0 COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,4H9T1@91061|Bacilli 91061|Bacilli M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE - 6.3.2.13,6.3.2.7 ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 - R02786,R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M BJHFPPGC_01372 1046629.Ssal_01843 0.0 972.0 COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4H9RY@91061|Bacilli 91061|Bacilli S Membrane protein involved in the export of O-antigen and teichoic acid ytgP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt,Polysacc_synt_C BJHFPPGC_01373 1046629.Ssal_01842 0.0 1724.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4HTQ4@91061|Bacilli 91061|Bacilli P cation transport ATPase pacL - - - - - - - - - - - Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 BJHFPPGC_01374 904306.HMPREF9192_0058 4.15e-257 705.0 COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4HAFQ@91061|Bacilli 91061|Bacilli E cystathionine metB GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 2.5.1.48 ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00420,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP BJHFPPGC_01375 1046629.Ssal_01839 3.56e-281 768.0 COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,4H9PE@91061|Bacilli 91061|Bacilli E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities malY - 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 BJHFPPGC_01376 1046629.Ssal_01838 0.0 1031.0 COG1621@1|root,COG1621@2|Bacteria 2|Bacteria G Belongs to the glycosyl hydrolase 32 family - - 3.2.1.26,3.2.1.65 ko:K01193,ko:K01212 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00801,R00802,R02410,R03635,R03921,R05624,R06088,R11311 RC00028,RC00077,RC03278 ko00000,ko00001,ko01000 - GH32 - Glyco_hydro_32N,Glyco_hydro_43 BJHFPPGC_01377 1046629.Ssal_01837 0.0 1439.0 COG1621@1|root,COG1621@2|Bacteria,1TR8C@1239|Firmicutes,4HBYU@91061|Bacilli 91061|Bacilli G Belongs to the glycosyl hydrolase 68 family sacB GO:0005575,GO:0005576 2.4.1.10,2.4.1.9 ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 - R04194,R05140 RC00077,RC00247 ko00000,ko00001,ko01000,ko01003 - GH68 - Glyco_hydro_68,Gram_pos_anchor,SH3_8 BJHFPPGC_01378 1046629.Ssal_01836 1.06e-145 410.0 COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,4H9Y0@91061|Bacilli 91061|Bacilli F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate upp GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 ko:K00761 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000 - - iSB619.SA_RS11010 UPRTase BJHFPPGC_01379 1046629.Ssal_01835 3.75e-135 383.0 COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,4HA8J@91061|Bacilli 91061|Bacilli OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins clpP GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0006355,GO:0006508,GO:0006515,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0030163,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051603,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease BJHFPPGC_01380 1046629.Ssal_01834 7.53e-94 275.0 COG3679@1|root,COG3679@2|Bacteria,1V3R6@1239|Firmicutes,4HGYS@91061|Bacilli 91061|Bacilli S Belongs to the UPF0342 family ylbF - - - - - - - - - - - Com_YlbF BJHFPPGC_01381 1046629.Ssal_01833 6.15e-62 189.0 COG4471@1|root,COG4471@2|Bacteria,1VF52@1239|Firmicutes,4HNTH@91061|Bacilli 91061|Bacilli S UPF0298 protein ylbG - - - - - - - - - - - DUF2129 BJHFPPGC_01382 1046629.Ssal_00984 1.11e-110 320.0 COG1943@1|root,COG1943@2|Bacteria,1TSQ0@1239|Firmicutes,4HDZ0@91061|Bacilli 91061|Bacilli L COG1943 Transposase and inactivated derivatives isplu5A - - ko:K07491 - - - - ko00000 - - - Y1_Tnp BJHFPPGC_01383 904306.HMPREF9192_0050 3.61e-267 733.0 COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,4H9PI@91061|Bacilli 91061|Bacilli E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component livJ - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 BJHFPPGC_01384 1046629.Ssal_01831 9.55e-189 526.0 COG0559@1|root,COG0559@2|Bacteria,1TR24@1239|Firmicutes,4HBFZ@91061|Bacilli 91061|Bacilli E Belongs to the binding-protein-dependent transport system permease family livH - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 BJHFPPGC_01385 1046629.Ssal_01830 1.34e-183 515.0 COG4177@1|root,COG4177@2|Bacteria,1TPMZ@1239|Firmicutes,4HDIU@91061|Bacilli 91061|Bacilli E Belongs to the binding-protein-dependent transport system permease family livM - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 BJHFPPGC_01386 1046629.Ssal_01829 5.4e-175 488.0 COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,4HASG@91061|Bacilli 91061|Bacilli E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component livG - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C BJHFPPGC_01387 1046629.Ssal_01828 4.6e-158 444.0 COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,4HABJ@91061|Bacilli 91061|Bacilli E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component livF - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran BJHFPPGC_01388 1046629.Ssal_01826 1.04e-141 401.0 COG0517@1|root,COG0517@2|Bacteria,1V4CD@1239|Firmicutes,4HGX4@91061|Bacilli 91061|Bacilli S CBS domain XK27_04065 - - ko:K04767 - - - - ko00000 - - - ACT,CBS BJHFPPGC_01389 1046629.Ssal_01825 2.34e-212 587.0 COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,4HAMU@91061|Bacilli 91061|Bacilli E Belongs to the cysteine synthase cystathionine beta- synthase family cysK - 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - PALP BJHFPPGC_01390 1046629.Ssal_01824 7.47e-141 398.0 COG1739@1|root,COG1739@2|Bacteria,1V6MQ@1239|Firmicutes,4HBIT@91061|Bacilli 91061|Bacilli S YigZ family yvyE - 3.4.13.9 ko:K01271 - - - - ko00000,ko01000,ko01002 - - - DUF1949,UPF0029 BJHFPPGC_01391 1046629.Ssal_01823 2.98e-304 831.0 COG4098@1|root,COG4098@2|Bacteria,1TPZE@1239|Firmicutes,4HB00@91061|Bacilli 91061|Bacilli L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein) comFA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - ko:K02240 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1 - - DEAD,Helicase_C,ResIII BJHFPPGC_01392 904306.HMPREF9192_0040 2.77e-126 362.0 COG1040@1|root,COG1040@2|Bacteria 2|Bacteria K competence protein comFC - - ko:K02242 - M00429 - - ko00000,ko00002,ko02044 - - - Pribosyltran BJHFPPGC_01393 1046629.Ssal_01821 2.38e-122 349.0 COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,4HFX9@91061|Bacilli 91061|Bacilli J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase hpf GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - ko:K05808 - - - - ko00000,ko03009 - - - Ribosom_S30AE_C,Ribosomal_S30AE BJHFPPGC_01394 1046629.Ssal_02154 0.0 1246.0 COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,4HAJB@91061|Bacilli 91061|Bacilli O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0030428,GO:0032502,GO:0042623,GO:0043170,GO:0043934,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 BJHFPPGC_01395 1046629.Ssal_02155 3.15e-126 359.0 COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,4HFZ2@91061|Bacilli 91061|Bacilli F Belongs to the purine pyrimidine phosphoribosyltransferase family hpt GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8,6.3.4.19 ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 - R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000,ko03016 - - - Pribosyltran BJHFPPGC_01396 1046629.Ssal_02156 3.96e-293 801.0 COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,4H9ZM@91061|Bacilli 91061|Bacilli D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine tilS - 2.4.2.8,6.3.4.19 ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 - R01132,R01229,R02142,R09597 RC00063,RC00122,RC02633,RC02634 ko00000,ko00001,ko01000,ko03016 - - - ATP_bind_3,TilS,TilS_C BJHFPPGC_01397 1046629.Ssal_02157 8.73e-297 811.0 COG2367@1|root,COG2367@2|Bacteria,1VGXR@1239|Firmicutes,4IPWW@91061|Bacilli 91061|Bacilli V Beta-lactamase enzyme family - - 3.5.2.6 ko:K01467 ko01501,ko02020,map01501,map02020 M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000 - - - Beta-lactamase2,SH3_8 BJHFPPGC_01399 322159.STER_0009 3.9e-79 235.0 COG2919@1|root,COG2919@2|Bacteria,1VKC5@1239|Firmicutes,4HR53@91061|Bacilli 91061|Bacilli D Septum formation initiator divIC - - ko:K13052 - - - - ko00000,ko03036 - - - DivIC BJHFPPGC_01400 1046629.Ssal_02160 1.87e-53 168.0 COG1188@1|root,COG1188@2|Bacteria,1VEI5@1239|Firmicutes,4HKJJ@91061|Bacilli 91061|Bacilli J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) yabO - - - - - - - - - - - S4 BJHFPPGC_01401 1046629.Ssal_02161 0.0 2228.0 COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,4H9NB@91061|Bacilli 91061|Bacilli L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF BJHFPPGC_01402 1046629.Ssal_02162 5.18e-134 379.0 COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,4HH2Z@91061|Bacilli 91061|Bacilli J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis pth GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro BJHFPPGC_01403 1046629.Ssal_02163 7.47e-259 710.0 COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,4H9SQ@91061|Bacilli 91061|Bacilli J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner ychF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - ko:K06942 - - - - ko00000,ko03009 - - - MMR_HSR1,YchF-GTPase_C BJHFPPGC_01404 1046629.Ssal_02164 8.11e-40 131.0 COG4481@1|root,COG4481@2|Bacteria,1VEQ7@1239|Firmicutes,4HNHU@91061|Bacilli 91061|Bacilli S Protein conserved in bacteria yyzM - - - - - - - - - - - DUF951 BJHFPPGC_01405 904306.HMPREF9192_1861 3.38e-254 699.0 COG0592@1|root,COG0592@2|Bacteria,1TQ7J@1239|Firmicutes,4H9TF@91061|Bacilli 91061|Bacilli L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 BJHFPPGC_01406 1046629.Ssal_00001 0.0 881.0 COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,4H9MW@91061|Bacilli 91061|Bacilli L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N BJHFPPGC_01407 1046629.Ssal_00002 6.53e-172 481.0 COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,4H9TB@91061|Bacilli 91061|Bacilli K Belongs to the ParB family spo0J GO:0005575,GO:0005622,GO:0005623,GO:0007059,GO:0008150,GO:0009295,GO:0009987,GO:0022603,GO:0042173,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0043937,GO:0043938,GO:0044424,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007 - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - HTH_3,KorB,ParBc BJHFPPGC_01408 1046629.Ssal_00003 5.83e-274 752.0 COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,4HA31@91061|Bacilli 91061|Bacilli O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain' htrA GO:0008150,GO:0009266,GO:0009628,GO:0050896 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 BJHFPPGC_01409 1046629.Ssal_00004 4.8e-104 301.0 COG1576@1|root,COG1576@2|Bacteria,1V3JM@1239|Firmicutes,4HFP8@91061|Bacilli 91061|Bacilli J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA rlmH - 2.1.1.177 ko:K00783 - - - - ko00000,ko01000,ko03009 - - - SPOUT_MTase BJHFPPGC_01410 1046629.Ssal_00005 5.23e-152 428.0 COG3619@1|root,COG3619@2|Bacteria 2|Bacteria S Protein of unknown function (DUF1275) yoaK - - - - - - - - - - - DUF1275 BJHFPPGC_01414 1046629.Ssal_00006 0.0 1611.0 COG4485@1|root,COG4485@2|Bacteria,1TRR1@1239|Firmicutes,4HCR9@91061|Bacilli 91061|Bacilli S Bacterial membrane protein YfhO XK27_10405 - - - - - - - - - - - YfhO BJHFPPGC_01415 904306.HMPREF9192_1872 0.0 1052.0 COG0488@1|root,COG0488@2|Bacteria,1TPW0@1239|Firmicutes,4HATH@91061|Bacilli 91061|Bacilli S abc transporter atp-binding protein ykpA - - - - - - - - - - - ABC_tran,ABC_tran_Xtn BJHFPPGC_01416 1046629.Ssal_00008 5.39e-193 537.0 COG1284@1|root,COG1284@2|Bacteria,1TR9J@1239|Firmicutes,4H9N6@91061|Bacilli 91061|Bacilli S membrane XK27_10395 - - - - - - - - - - - DUF2179,YitT_membrane BJHFPPGC_01417 1046629.Ssal_00009 4.36e-240 660.0 COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,4HA1K@91061|Bacilli 91061|Bacilli J Tryptophanyl-tRNA synthetase trpS GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b BJHFPPGC_01418 1046629.Ssal_00010 0.0 941.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,4H9V3@91061|Bacilli 91061|Bacilli F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth guaB GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - CBS,IMPDH BJHFPPGC_01419 1046629.Ssal_00011 1.09e-253 697.0 COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,4HA0W@91061|Bacilli 91061|Bacilli L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SMC_N BJHFPPGC_01420 1046629.Ssal_00012 2.94e-75 226.0 COG2501@1|root,COG2501@2|Bacteria,1VKF4@1239|Firmicutes,4HRX5@91061|Bacilli 91061|Bacilli S S4 domain protein YaaA yaaA - - - - - - - - - - - S4_2 BJHFPPGC_01421 1046629.Ssal_00013 4.45e-292 798.0 COG0612@1|root,COG0612@2|Bacteria,1TPN6@1239|Firmicutes,4H9P5@91061|Bacilli 91061|Bacilli S Peptidase M16 albE - - - - - - - - - - - Peptidase_M16_C BJHFPPGC_01422 1046629.Ssal_00014 1.77e-298 815.0 COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,4H9YG@91061|Bacilli 91061|Bacilli S Peptidase M16 ymfH - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C BJHFPPGC_01423 1046629.Ssal_00015 7.51e-163 459.0 COG1426@1|root,COG1426@2|Bacteria 2|Bacteria S sequence-specific DNA binding - - - ko:K15539 - - - - ko00000 - - - DUF4115,HTH_25,HTH_3 BJHFPPGC_01424 1046629.Ssal_00016 2.2e-117 337.0 COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,4HCEX@91061|Bacilli 91061|Bacilli I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pgsA GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.5 ko:K00995 ko00564,ko01100,map00564,map01100 - R01801 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - iSB619.SA_RS06365 CDP-OH_P_transf BJHFPPGC_01425 1046629.Ssal_00017 1.01e-190 530.0 COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4H9R8@91061|Bacilli 91061|Bacilli P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates ecfA1 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - ko:K16786 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran BJHFPPGC_01426 1046629.Ssal_00018 2.91e-192 534.0 COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4HA7T@91061|Bacilli 91061|Bacilli P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates ecfA2 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran BJHFPPGC_01427 264199.stu2007 6.19e-170 476.0 COG0619@1|root,COG0619@2|Bacteria,1TQ0E@1239|Firmicutes,4H9VT@91061|Bacilli 91061|Bacilli P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates ecfT GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - CbiQ BJHFPPGC_01428 435842.HMPREF0848_01703 1.56e-102 300.0 COG1388@1|root,COG1388@2|Bacteria,1VA10@1239|Firmicutes,4HMUH@91061|Bacilli 91061|Bacilli M LysM domain protein lytE - - - - - - - - - - - LysM BJHFPPGC_01429 1046629.Ssal_00021 4.38e-122 353.0 COG0741@1|root,COG0741@2|Bacteria,1VGPA@1239|Firmicutes,4HP1I@91061|Bacilli 91061|Bacilli M Immunodominant staphylococcal antigen A isaA - - - - - - - - - - - DUF348,G5,LysM,SLT,Transglycosylas BJHFPPGC_01430 1046629.Ssal_00022 0.0 1061.0 COG4485@1|root,COG4485@2|Bacteria,1V0XZ@1239|Firmicutes,4HEBN@91061|Bacilli 91061|Bacilli S Bacterial membrane protein, YfhO - - - - - - - - - - - - - BJHFPPGC_01431 1046629.Ssal_00023 8.99e-277 756.0 COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,4HBJ6@91061|Bacilli 91061|Bacilli J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA GO:0002097,GO:0002098,GO:0002143,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans BJHFPPGC_01432 467705.SGO_0023 2.48e-128 366.0 COG2095@1|root,COG2095@2|Bacteria,1V81W@1239|Firmicutes,4HIUV@91061|Bacilli 91061|Bacilli U UPF0056 membrane protein yvbG - - ko:K05595 - - - - ko00000,ko02000 2.A.95.1 - - MarC BJHFPPGC_01433 1046629.Ssal_00025 0.0 1228.0 COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,4HA6S@91061|Bacilli 91061|Bacilli D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 gidA GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - ko:K03495 - - R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 - - - GIDA,GIDA_assoc BJHFPPGC_01434 904306.HMPREF9192_1894 0.0 1217.0 COG3887@1|root,COG3887@2|Bacteria,1TPGP@1239|Firmicutes,4HBVH@91061|Bacilli 91061|Bacilli T signaling protein consisting of a modified GGDEF domain and a DHH domain yybT - - - - - - - - - - - DHH,DHHA1 BJHFPPGC_01435 1046629.Ssal_00027 1.77e-98 286.0 COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,4HIKJ@91061|Bacilli 91061|Bacilli J binds to the 23S rRNA rplI GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02939 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L9_C,Ribosomal_L9_N BJHFPPGC_01436 1046629.Ssal_00028 1.1e-313 856.0 COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,4H9Y8@91061|Bacilli 91061|Bacilli L Participates in initiation and elongation during chromosome replication dnaC GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C BJHFPPGC_01437 1046629.Ssal_00029 4.18e-61 188.0 COG4466@1|root,COG4466@2|Bacteria,1VPZY@1239|Firmicutes,4HSFF@91061|Bacilli 91061|Bacilli S Biofilm formation stimulator VEG WQ51_01655 - - - - - - - - - - - VEG BJHFPPGC_01438 1046629.Ssal_00030 1.25e-141 400.0 COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,4HAC9@91061|Bacilli 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit rpsD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - ko:K02986 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S4,S4 BJHFPPGC_01439 1260356.D920_01191 5.32e-13 63.9 2914P@1|root,2ZNS1@2|Bacteria,1W3FT@1239|Firmicutes,4I23Q@91061|Bacilli,4B40K@81852|Enterococcaceae 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_01440 1046629.Ssal_00032 7.66e-71 214.0 COG3759@1|root,COG3759@2|Bacteria,1VAEU@1239|Firmicutes 1239|Firmicutes M Membrane XK27_04840 - - ko:K08987 - - - - ko00000 - - - DUF1304 BJHFPPGC_01441 1046629.Ssal_00033 2.69e-122 349.0 COG1309@1|root,COG1309@2|Bacteria 2|Bacteria K transcriptional regulator XK27_06935 - - - - - - - - - - - TetR_C_8,TetR_N BJHFPPGC_01442 904306.HMPREF9192_1903 3.48e-260 748.0 COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,4H9T9@91061|Bacilli 91061|Bacilli V domain protein XK27_06930 - - ko:K01421 - - - - ko00000 - - - ABC2_membrane,ABC2_membrane_3,DUF3533 BJHFPPGC_01443 1046629.Ssal_00035 7.61e-147 420.0 COG3595@1|root,COG3595@2|Bacteria,1VGGF@1239|Firmicutes 1239|Firmicutes S Putative adhesin - - - - - - - - - - - - DUF4097 BJHFPPGC_01444 904306.HMPREF9192_1905 1.91e-95 282.0 COG4709@1|root,COG4709@2|Bacteria,1VBG6@1239|Firmicutes,4HSRQ@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF1700) - - - - - - - - - - - - DUF1700 BJHFPPGC_01445 904306.HMPREF9192_1906 3.43e-66 201.0 COG1695@1|root,COG1695@2|Bacteria,1VIVQ@1239|Firmicutes,4IR4R@91061|Bacilli 91061|Bacilli K transcriptional regulator, PadR family XK27_06915 - - ko:K10947 - - - - ko00000,ko03000 - - - PadR BJHFPPGC_01446 904306.HMPREF9192_1907 2.17e-146 412.0 COG0494@1|root,COG0494@2|Bacteria,1V6SF@1239|Firmicutes,4HG46@91061|Bacilli 91061|Bacilli L hydrolase XK27_06885 - - - - - - - - - - - NUDIX BJHFPPGC_01450 1046629.Ssal_00051 1.22e-26 97.4 COG0267@1|root,COG0267@2|Bacteria 2|Bacteria J Belongs to the bacterial ribosomal protein bL33 family rpmG GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046677,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02913 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L33 BJHFPPGC_01451 1046629.Ssal_00052 3.57e-35 119.0 COG0333@1|root,COG0333@2|Bacteria,1VKMZ@1239|Firmicutes,4HR2Q@91061|Bacilli 91061|Bacilli J Belongs to the bacterial ribosomal protein bL32 family rpmF - - ko:K02911 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_L32p BJHFPPGC_01452 1046629.Ssal_00053 1.01e-276 755.0 COG0620@1|root,COG0620@2|Bacteria,1TPDQ@1239|Firmicutes,4HADW@91061|Bacilli 91061|Bacilli E Methionine synthase metE - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 BJHFPPGC_01453 1046629.Ssal_00054 7.01e-47 162.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli 91061|Bacilli G pts system - - - ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 M00271 - - ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC BJHFPPGC_01454 1046629.Ssal_00054 1.2e-138 402.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli 91061|Bacilli G pts system - - - ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 M00271 - - ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC BJHFPPGC_01455 1046629.Ssal_00054 2.73e-30 117.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli 91061|Bacilli G pts system - - - ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 M00271 - - ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC BJHFPPGC_01456 1046629.Ssal_00055 1.47e-302 825.0 COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,4HAM2@91061|Bacilli 91061|Bacilli J histidyl-tRNA synthetase hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_His BJHFPPGC_01458 1046629.Ssal_00058 0.0 1130.0 COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,4HACD@91061|Bacilli 91061|Bacilli J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) aspS - 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - GAD,tRNA-synt_2,tRNA_anti-codon BJHFPPGC_01459 904306.HMPREF9192_1927 1.03e-213 591.0 COG1284@1|root,COG1284@2|Bacteria,1TRBT@1239|Firmicutes,4HBPR@91061|Bacilli 91061|Bacilli S cog cog1284 XK27_01785 - - - - - - - - - - - DUF2179,YitT_membrane BJHFPPGC_01460 1046629.Ssal_00060 1.19e-154 436.0 COG3022@1|root,COG3022@2|Bacteria,1TR33@1239|Firmicutes,4HFN2@91061|Bacilli 91061|Bacilli S Belongs to the UPF0246 family XK27_08125 - - ko:K09861 - - - - ko00000 - - - H2O2_YaaD BJHFPPGC_01461 1046629.Ssal_00061 1.65e-145 409.0 COG0602@1|root,COG0602@2|Bacteria,1V1HG@1239|Firmicutes,4HGJ9@91061|Bacilli 91061|Bacilli O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine nrdG - 1.97.1.4 ko:K04068 - - R04710 - ko00000,ko01000 - - - Fer4_12,Radical_SAM BJHFPPGC_01462 1046629.Ssal_00062 2.53e-107 310.0 COG3981@1|root,COG3981@2|Bacteria,1V1C4@1239|Firmicutes,4HG6C@91061|Bacilli 91061|Bacilli K acetyltransferase - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_3 BJHFPPGC_01463 435842.HMPREF0848_01736 7.68e-20 80.1 2DEKJ@1|root,2ZNBP@2|Bacteria,1TXD1@1239|Firmicutes,4HZYT@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_01464 1046629.Ssal_00064 0.0 1478.0 COG1327@1|root,COG1328@1|root,COG1327@2|Bacteria,COG1328@2|Bacteria,1TR9K@1239|Firmicutes,4HBIY@91061|Bacilli 91061|Bacilli F Ribonucleoside-triphosphate reductase nrdD - 1.1.98.6 ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000 - - - ATP-cone,NRDD BJHFPPGC_01465 1046629.Ssal_00065 0.0 1012.0 2F2IJ@1|root,33VFI@2|Bacteria,1V9D8@1239|Firmicutes,4HS77@91061|Bacilli 91061|Bacilli S the current gene model (or a revised gene model) may contain a frame shift - - - - - - - - - - - - - BJHFPPGC_01466 1046629.Ssal_00066 1.34e-62 192.0 COG3906@1|root,COG3906@2|Bacteria,1VAPW@1239|Firmicutes,4HKV7@91061|Bacilli 91061|Bacilli S Belongs to the UPF0473 family yrzB - - - - - - - - - - - DUF1292 BJHFPPGC_01467 435842.HMPREF0848_01740 9.82e-92 268.0 COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,4HH04@91061|Bacilli 91061|Bacilli L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA yrrK GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K07447 - - - - ko00000,ko01000 - - - RuvX BJHFPPGC_01468 1046629.Ssal_00068 9.75e-59 181.0 COG4472@1|root,COG4472@2|Bacteria,1VAC4@1239|Firmicutes,4HKD0@91061|Bacilli 91061|Bacilli S Belongs to the UPF0297 family yrzL - - - - - - - - - - - DUF965 BJHFPPGC_01469 1046629.Ssal_00069 1.73e-36 123.0 COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes,4HNIK@91061|Bacilli 91061|Bacilli J Belongs to the bacterial ribosomal protein bL28 family rpmB - - ko:K02902 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L28 BJHFPPGC_01470 1046629.Ssal_00070 3.43e-299 816.0 COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,4HAIS@91061|Bacilli 91061|Bacilli L ATPase related to the helicase subunit of the Holliday junction resolvase rarA - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N BJHFPPGC_01472 1046629.Ssal_00076 1.52e-116 333.0 COG0563@1|root,COG0563@2|Bacteria,1V7AW@1239|Firmicutes,4HH8A@91061|Bacilli 91061|Bacilli F topology modulation protein flaR - - - - - - - - - - - - BJHFPPGC_01473 1046629.Ssal_00077 3.87e-316 860.0 COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,4H9YT@91061|Bacilli 91061|Bacilli F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - - Adenylsucc_synt BJHFPPGC_01474 1046629.Ssal_00078 1.55e-104 301.0 COG0394@1|root,COG0394@2|Bacteria,1V6SG@1239|Firmicutes,4HIZN@91061|Bacilli 91061|Bacilli T Belongs to the low molecular weight phosphotyrosine protein phosphatase family ptpA - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - LMWPc BJHFPPGC_01475 1046629.Ssal_00079 1.21e-47 157.0 COG4642@1|root,COG4642@2|Bacteria,1TRNW@1239|Firmicutes 1239|Firmicutes S MORN repeat protein - - - - - - - - - - - - MORN BJHFPPGC_01476 1046629.Ssal_00080 0.0 1156.0 COG1835@1|root,COG1835@2|Bacteria,1U6DU@1239|Firmicutes,4H9XT@91061|Bacilli 91061|Bacilli I Acyltransferase XK27_09800 - - - - - - - - - - - Acyl_transf_3 BJHFPPGC_01477 1046629.Ssal_00081 7.25e-240 659.0 COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,4HBMW@91061|Bacilli 91061|Bacilli L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing ruvB - 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N BJHFPPGC_01478 1046629.Ssal_00083 4.29e-64 196.0 COG0051@1|root,COG0051@2|Bacteria,1V6C9@1239|Firmicutes,4HIKH@91061|Bacilli 91061|Bacilli J Involved in the binding of tRNA to the ribosomes rpsJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02946 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S10 BJHFPPGC_01479 1046629.Ssal_00084 3.17e-142 402.0 COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,4HAEN@91061|Bacilli 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit rplC GO:0008150,GO:0009893,GO:0010468,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0044087,GO:0044089,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090070,GO:2000232,GO:2000234 - ko:K02906 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L3 BJHFPPGC_01480 1046629.Ssal_00085 2.13e-135 384.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,4HB01@91061|Bacilli 91061|Bacilli J Forms part of the polypeptide exit tunnel rplD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02926 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L4 BJHFPPGC_01481 264199.stu1932 6e-60 185.0 COG0089@1|root,COG0089@2|Bacteria,1VA4W@1239|Firmicutes,4HKCV@91061|Bacilli 91061|Bacilli J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome rplW GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02892 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L23 BJHFPPGC_01482 1046629.Ssal_00087 5.06e-196 543.0 COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,4HAE8@91061|Bacilli 91061|Bacilli J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity rplB GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02886 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L2,Ribosomal_L2_C BJHFPPGC_01483 1000570.HMPREF9966_1567 8.13e-62 189.0 COG0185@1|root,COG0185@2|Bacteria,1V6CX@1239|Firmicutes,4HIG0@91061|Bacilli,42DQ5@671232|Streptococcus anginosus group 91061|Bacilli J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA rpsS GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - ko:K02965 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S19 BJHFPPGC_01484 1046629.Ssal_00089 1.21e-71 216.0 COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,4HIK2@91061|Bacilli 91061|Bacilli J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome rplV GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02890 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L22 BJHFPPGC_01485 1046629.Ssal_00090 9.44e-153 429.0 COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,4HAUR@91061|Bacilli 91061|Bacilli J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation rpsC GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02982 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KH_2,Ribosomal_S3_C BJHFPPGC_01486 1046629.Ssal_00091 4.35e-94 274.0 COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,4HFPN@91061|Bacilli 91061|Bacilli J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs rplP GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02878 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L16 BJHFPPGC_01487 1046629.Ssal_00092 6.2e-35 119.0 COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,4HNUP@91061|Bacilli 91061|Bacilli J Belongs to the universal ribosomal protein uL29 family rpmC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02904 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L29 BJHFPPGC_01488 1046629.Ssal_00093 3.08e-52 164.0 COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,4HKDN@91061|Bacilli 91061|Bacilli J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA rpsQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02961 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S17 BJHFPPGC_01489 1046629.Ssal_00094 2.55e-79 236.0 COG0093@1|root,COG0093@2|Bacteria,1V3N0@1239|Firmicutes,4HGYR@91061|Bacilli 91061|Bacilli J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome rplN GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - ko:K02874 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L14 BJHFPPGC_01490 1046629.Ssal_00095 5.67e-64 195.0 COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,4HKH9@91061|Bacilli 91061|Bacilli J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit rplX GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02895 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KOW,ribosomal_L24 BJHFPPGC_01491 1046629.Ssal_00096 5.86e-122 348.0 COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,4HBAX@91061|Bacilli 91061|Bacilli J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits rplE GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02931 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L5,Ribosomal_L5_C BJHFPPGC_01492 1000570.HMPREF9966_1576 2.03e-39 130.0 COG0199@1|root,COG0199@2|Bacteria,1VEF6@1239|Firmicutes,4HNKX@91061|Bacilli,42EG0@671232|Streptococcus anginosus group 91061|Bacilli J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site rpsN - - ko:K02954 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S14 BJHFPPGC_01493 1046629.Ssal_00098 3.78e-88 259.0 COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,4HH32@91061|Bacilli 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit rpsH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02994 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S8 BJHFPPGC_01494 1046629.Ssal_00099 5.88e-121 345.0 COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,4HFQD@91061|Bacilli 91061|Bacilli J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center rplF GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02933 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L6 BJHFPPGC_01495 1046629.Ssal_00100 7.15e-75 224.0 COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,4HIGF@91061|Bacilli 91061|Bacilli J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance rplR GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02881 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L18p BJHFPPGC_01496 1046629.Ssal_00101 7e-104 301.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,4HFN4@91061|Bacilli 91061|Bacilli J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body rpsE GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02988 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S5,Ribosomal_S5_C BJHFPPGC_01497 1046629.Ssal_00102 9.89e-33 113.0 COG1841@1|root,COG1841@2|Bacteria,1VEG4@1239|Firmicutes,4HNHF@91061|Bacilli 91061|Bacilli J ribosomal protein l30 rpmD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02907 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L30 BJHFPPGC_01498 1046629.Ssal_00103 8.47e-85 251.0 COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,4HFPW@91061|Bacilli 91061|Bacilli J binds to the 23S rRNA rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02876 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27A BJHFPPGC_01499 1046629.Ssal_00104 4.48e-295 807.0 COG0201@1|root,COG0201@2|Bacteria,1TPHB@1239|Firmicutes,4HAWH@91061|Bacilli 91061|Bacilli U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY BJHFPPGC_01500 904306.HMPREF9192_1977 9.83e-148 416.0 COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,4HA89@91061|Bacilli 91061|Bacilli F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk GO:0003674,GO:0003824,GO:0004017,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ADK,ADK_lid BJHFPPGC_01501 1046629.Ssal_00106 6.91e-45 145.0 COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,4HKF4@91061|Bacilli 91061|Bacilli J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex infA GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - ko:K02518 - - - - ko00000,ko03012 - - - eIF-1a BJHFPPGC_01502 1123301.KB904201_gene1724 3.26e-22 85.5 COG0257@1|root,COG0257@2|Bacteria 2|Bacteria J Belongs to the bacterial ribosomal protein bL36 family rpmJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02919 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L36 BJHFPPGC_01503 1046629.Ssal_00108 4.42e-75 225.0 COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,4HGX6@91061|Bacilli 91061|Bacilli J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits rpsM GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02952 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S13 BJHFPPGC_01504 1046629.Ssal_00109 1.63e-82 244.0 COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,4HH2T@91061|Bacilli 91061|Bacilli J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome rpsK GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02948 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S11 BJHFPPGC_01505 1046629.Ssal_00110 7.63e-220 607.0 COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,4H9R1@91061|Bacilli 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L BJHFPPGC_01506 1046629.Ssal_00111 3.03e-83 246.0 COG0203@1|root,COG0203@2|Bacteria,1V6JQ@1239|Firmicutes,4HGX2@91061|Bacilli 91061|Bacilli J ribosomal protein l17 rplQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02879 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L17 BJHFPPGC_01507 1046629.Ssal_00112 2.3e-313 853.0 COG3572@1|root,COG3572@2|Bacteria,1TW3D@1239|Firmicutes,4HTV4@91061|Bacilli 91061|Bacilli H gamma-glutamylcysteine synthetase - - - - - - - - - - - - GCS2 BJHFPPGC_01509 1046629.Ssal_00114 8.52e-212 585.0 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,4H9ZU@91061|Bacilli 91061|Bacilli G aldolase fba - 4.1.2.13,4.1.2.29 ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568,R05378 RC00438,RC00439,RC00603,RC00604,RC00721 ko00000,ko00001,ko00002,ko01000 - - - F_bP_aldolase BJHFPPGC_01511 1046629.Ssal_00117 1.37e-123 353.0 COG4475@1|root,COG4475@2|Bacteria,1V3H0@1239|Firmicutes,4HH6F@91061|Bacilli 91061|Bacilli S Belongs to the UPF0340 family ywlG - - - - - - - - - - - DUF436 BJHFPPGC_01512 1046629.Ssal_00118 1.82e-164 460.0 COG2188@1|root,COG2188@2|Bacteria,1TRF6@1239|Firmicutes,4HDCX@91061|Bacilli 91061|Bacilli K trehalose operon treR - - ko:K03486 - - - - ko00000,ko03000 - - - GntR,UTRA BJHFPPGC_01513 904306.HMPREF9192_1991 6.21e-32 122.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli 91061|Bacilli G pts system treP - 2.7.1.201 ko:K02817,ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 M00270 R02780 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.13,4.A.1.2.4,4.A.1.2.8 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC BJHFPPGC_01514 1046629.Ssal_00119 4.42e-139 412.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli 91061|Bacilli G pts system treP - 2.7.1.201 ko:K02817,ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 M00270 R02780 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.13,4.A.1.2.4,4.A.1.2.8 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC BJHFPPGC_01515 1046629.Ssal_00120 0.0 1097.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli 91061|Bacilli G COG0366 Glycosidases treC - 3.2.1.93 ko:K01226 ko00500,map00500 - R00837,R06113 RC00049 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,DUF3459,Malt_amylase_C BJHFPPGC_01516 435842.HMPREF0848_01786 0.0 1261.0 COG3590@1|root,COG3590@2|Bacteria,1TQTA@1239|Firmicutes,4HDSF@91061|Bacilli 91061|Bacilli O Peptidase family M13 pepO - - ko:K07386 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M13,Peptidase_M13_N BJHFPPGC_01517 904306.HMPREF9192_1994 0.0 1670.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,4HAN8@91061|Bacilli 91061|Bacilli C belongs to the iron- containing alcohol dehydrogenase family adh - 1.1.1.1,1.2.1.10 ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 - R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 ko00000,ko00001,ko01000 - - iSB619.SA_RS00885 Aldedh,Fe-ADH BJHFPPGC_01519 435842.HMPREF0848_01381 6.92e-05 52.8 COG3064@1|root,COG3064@2|Bacteria,1VK5M@1239|Firmicutes,4HS44@91061|Bacilli 91061|Bacilli M Membrane yebC - - - - - - - - - - - zf-ribbon_3,zinc_ribbon_2 BJHFPPGC_01520 1046629.Ssal_00127 0.0 954.0 COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,4H9R7@91061|Bacilli 91061|Bacilli E Threonine synthase thrC - 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_synth_N BJHFPPGC_01521 1046629.Ssal_00128 2.72e-283 777.0 COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,4H9Y2@91061|Bacilli 91061|Bacilli V Mate efflux family protein norN - - - - - - - - - - - MatE BJHFPPGC_01522 1046629.Ssal_00129 1.87e-76 228.0 COG1302@1|root,COG1302@2|Bacteria,1V3Q6@1239|Firmicutes,4HHYJ@91061|Bacilli 91061|Bacilli S cog cog1302 asp - - - - - - - - - - - Asp23 BJHFPPGC_01523 1046629.Ssal_00130 0.0 1048.0 COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,4HBSE@91061|Bacilli 91061|Bacilli S kinase related to dihydroxyacetone kinase yloV - - ko:K07030 - - - - ko00000 - - - Dak1_2,Dak2 BJHFPPGC_01524 1046629.Ssal_00131 0.0 1125.0 COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,4H9ZG@91061|Bacilli 91061|Bacilli E Belongs to the IlvD Edd family ilvD - 4.2.1.9 ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 M00019,M00570,M00582 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ILVD_EDD BJHFPPGC_01525 1046629.Ssal_00132 0.0 1097.0 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4H9VR@91061|Bacilli 91061|Bacilli EH Acetolactate synthase ilvB - 2.2.1.6 ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 M00019,M00570,M00582 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - iYO844.BSU28310 TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N BJHFPPGC_01526 904306.HMPREF9192_2002 7.09e-101 293.0 COG0440@1|root,COG0440@2|Bacteria,1V2AJ@1239|Firmicutes,4HDY5@91061|Bacilli 91061|Bacilli E Acetolactate synthase ilvN GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 M00019,M00570,M00582 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ACT,ACT_5,ALS_ss_C BJHFPPGC_01527 322159.STER_1848 1.73e-246 676.0 COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,4HADK@91061|Bacilli 91061|Bacilli H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate ilvC - 1.1.1.86 ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R03051,R04439,R04440,R05068,R05069,R05071 RC00726,RC00836,RC00837,RC01726 ko00000,ko00001,ko00002,ko01000 - - - IlvC,IlvN BJHFPPGC_01528 904306.HMPREF9192_2004 1.65e-304 830.0 COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,4H9YV@91061|Bacilli 91061|Bacilli J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b BJHFPPGC_01529 1046629.Ssal_00136 0.0 1527.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli 91061|Bacilli M penicillin-binding protein pbp1B - 2.4.1.129 ko:K03693,ko:K12551 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase BJHFPPGC_01530 1046629.Ssal_00138 0.0 2333.0 COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,4H9PK@91061|Bacilli 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 BJHFPPGC_01531 904306.HMPREF9192_2007 0.0 2373.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,4HA24@91061|Bacilli 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 BJHFPPGC_01532 1046629.Ssal_00141 4.59e-90 263.0 COG4699@1|root,COG4699@2|Bacteria,1VHC7@1239|Firmicutes,4HS15@91061|Bacilli 91061|Bacilli S cog cog4699 - - - - - - - - - - - - DUF1033 BJHFPPGC_01533 1046629.Ssal_00142 4.44e-224 617.0 COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,4HB0C@91061|Bacilli 91061|Bacilli NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB comGA - - ko:K02243 - M00429 - - ko00000,ko00002,ko02044 3.A.14.1 - - T2SSE BJHFPPGC_01534 1046629.Ssal_00143 6.29e-184 513.0 COG1459@1|root,COG1459@2|Bacteria 2|Bacteria U protein transport across the cell outer membrane cglB - - ko:K02244 - M00429 - - ko00000,ko00002,ko02044 3.A.14.1 - - T2SSF BJHFPPGC_01535 1046629.Ssal_00144 1.1e-62 192.0 COG4537@1|root,COG4537@2|Bacteria,1VFI9@1239|Firmicutes,4HNNT@91061|Bacilli 91061|Bacilli U Required for transformation and DNA binding comGC GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944 - ko:K02245 - M00429 - - ko00000,ko00002,ko02044 - - - N_methyl BJHFPPGC_01536 1046629.Ssal_00145 9.78e-92 269.0 COG2165@1|root,33A38@2|Bacteria,1VPGT@1239|Firmicutes,4HRZ0@91061|Bacilli 91061|Bacilli NU Competence protein cglD - - ko:K02246 - M00429 - - ko00000,ko00002,ko02044 - - - - BJHFPPGC_01537 873449.STRCR_0577 1.01e-20 85.1 COG2165@1|root,2ZS6J@2|Bacteria,1W385@1239|Firmicutes 1239|Firmicutes NU Type II secretory pathway pseudopilin - - - - - - - - - - - - PulG BJHFPPGC_01538 1046629.Ssal_00147 3.23e-93 273.0 COG4940@1|root,COG4940@2|Bacteria,1VKRP@1239|Firmicutes,4HR6S@91061|Bacilli 91061|Bacilli U Competence protein ComGF comGF - - ko:K02248 - M00429 - - ko00000,ko00002,ko02044 - - - ComGF,N_methyl BJHFPPGC_01539 1198676.SMUGS5_08910 7.17e-17 80.5 COG4940@1|root,COG4940@2|Bacteria,1VJKM@1239|Firmicutes,4HQDT@91061|Bacilli 91061|Bacilli U Putative Competence protein ComGF - - - ko:K02248 - M00429 - - ko00000,ko00002,ko02044 - - - ComGF,N_methyl BJHFPPGC_01540 904306.HMPREF9192_2017 9.71e-226 622.0 COG0827@1|root,COG0827@2|Bacteria,1TRIQ@1239|Firmicutes,4H9SE@91061|Bacilli 91061|Bacilli L DNA methylase ytxK - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_Mtase BJHFPPGC_01541 904306.HMPREF9192_2018 1.64e-282 772.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,4HA7K@91061|Bacilli 91061|Bacilli F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction ackA - 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - Acetate_kinase BJHFPPGC_01542 1046629.Ssal_00151 1.05e-36 124.0 COG1476@1|root,COG1476@2|Bacteria 2|Bacteria K sequence-specific DNA binding lanR - - ko:K07729 - - - - ko00000,ko03000 - - - HTH_3 BJHFPPGC_01543 1046629.Ssal_00152 2e-134 383.0 COG1266@1|root,COG1266@2|Bacteria 2|Bacteria V CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi BJHFPPGC_01545 264199.stu1853 3.44e-120 347.0 COG1266@1|root,COG1266@2|Bacteria,1VEE2@1239|Firmicutes,4HP4A@91061|Bacilli 91061|Bacilli S CAAX amino terminal protease family protein - - - ko:K07052 - - - - ko00000 - - - Abi BJHFPPGC_01546 904306.HMPREF9192_2022 4.56e-168 471.0 COG0345@1|root,COG0345@2|Bacteria,1TP1E@1239|Firmicutes,4HCBY@91061|Bacilli 91061|Bacilli E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC - 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - - F420_oxidored,P5CR_dimer BJHFPPGC_01547 1046629.Ssal_00156 6.14e-259 709.0 COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,4H9SM@91061|Bacilli 91061|Bacilli G COG1363 Cellulase M and related proteins pepA - 3.4.11.7 ko:K01261,ko:K01269 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M42 BJHFPPGC_01549 1046629.Ssal_00158 2.86e-72 216.0 COG0526@1|root,COG0526@2|Bacteria,1VAS6@1239|Firmicutes,4HKGM@91061|Bacilli 91061|Bacilli CO Thioredoxin ytpP GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - - - - - - - - - - Thioredoxin BJHFPPGC_01551 1046629.Ssal_00160 4.53e-146 411.0 COG0073@1|root,COG0073@2|Bacteria,1V7QA@1239|Firmicutes,4HJBD@91061|Bacilli 91061|Bacilli J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily XK27_10290 - - ko:K06878 - - - - ko00000 - - - DUF4479,tRNA_bind BJHFPPGC_01552 1046629.Ssal_00162 8.45e-151 426.0 COG1266@1|root,COG1266@2|Bacteria,1VKZ6@1239|Firmicutes,4IQWN@91061|Bacilli 91061|Bacilli S CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi BJHFPPGC_01553 322159.STER_1821 2.58e-85 251.0 COG0629@1|root,COG0629@2|Bacteria,1VXMZ@1239|Firmicutes,4HXCW@91061|Bacilli 91061|Bacilli L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB BJHFPPGC_01554 1046629.Ssal_00164 1.34e-114 329.0 COG0590@1|root,COG0590@2|Bacteria,1V3HZ@1239|Firmicutes,4HH7S@91061|Bacilli 91061|Bacilli FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) tadA GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 3.5.4.33 ko:K11991 - - R10223 RC00477 ko00000,ko01000,ko03016 - - - MafB19-deam BJHFPPGC_01557 904306.HMPREF9192_2035 2.61e-199 552.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase rrmA - 2.1.1.187 ko:K00563,ko:K10947 - - R07233 RC00003 ko00000,ko01000,ko03000,ko03009 - - - Methyltransf_11,Methyltransf_25,Methyltransf_31 BJHFPPGC_01558 904306.HMPREF9192_2036 5.1e-162 455.0 COG0546@1|root,COG0546@2|Bacteria,1V73N@1239|Firmicutes,4IU82@91061|Bacilli 91061|Bacilli S HAD hydrolase, family IA, variant - - - ko:K07025 - - - - ko00000 - - - HAD_2 BJHFPPGC_01559 1046629.Ssal_00170 3.08e-109 320.0 COG2171@1|root,COG2171@2|Bacteria,1TQUJ@1239|Firmicutes,4H9KY@91061|Bacilli 91061|Bacilli E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate dapH - 2.3.1.117,2.3.1.89 ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 M00016,M00525 R04364,R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU14180 DapH_N,Hexapep BJHFPPGC_01560 1046629.Ssal_00172 1.56e-279 763.0 COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,4H9SG@91061|Bacilli 91061|Bacilli E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate hipO GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0050118,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.47 ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R02733 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 BJHFPPGC_01561 904306.HMPREF9192_2039 1.34e-120 344.0 COG0212@1|root,COG0212@2|Bacteria,1VA91@1239|Firmicutes,4HM35@91061|Bacilli 91061|Bacilli H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family fthC GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0030272,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 - R02301 RC00183 ko00000,ko00001,ko01000 - - - 5-FTHF_cyc-lig BJHFPPGC_01562 904306.HMPREF9192_2040 1.55e-150 424.0 COG0705@1|root,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,4HCDF@91061|Bacilli 91061|Bacilli O membrane protein (homolog of Drosophila rhomboid) gluP - 3.4.21.105 ko:K19225 - - - - ko00000,ko01000,ko01002 - - - Rhomboid,TPR_2,TPR_8 BJHFPPGC_01563 904306.HMPREF9192_2041 1.53e-215 595.0 COG1210@1|root,COG1210@2|Bacteria,1TQ24@1239|Firmicutes,4HATY@91061|Bacilli 91061|Bacilli M UTP-glucose-1-phosphate uridylyltransferase galU - 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase BJHFPPGC_01564 1046629.Ssal_00176 2.82e-234 646.0 COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,4HAXW@91061|Bacilli 91061|Bacilli I Glycerol-3-phosphate dehydrogenase gpsA GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0047952,GO:0055114 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N BJHFPPGC_01565 1046629.Ssal_00177 2.54e-124 355.0 2BY0N@1|root,321KG@2|Bacteria 2|Bacteria S Psort location CytoplasmicMembrane, score XK27_08585 - - ko:K16926 - M00582 - - ko00000,ko00002,ko02000 3.A.1.31 - - Trep_Strep BJHFPPGC_01566 1046629.Ssal_00179 2.89e-179 500.0 COG2116@1|root,COG2116@2|Bacteria,1V164@1239|Firmicutes,4HFJC@91061|Bacilli 91061|Bacilli P Formate nitrite transporter nirC_1 - - - - - - - - - - - Form_Nir_trans BJHFPPGC_01567 1046629.Ssal_00180 1.72e-305 832.0 COG0431@1|root,COG2461@1|root,COG0431@2|Bacteria,COG2461@2|Bacteria,1TPRA@1239|Firmicutes,4HDA5@91061|Bacilli 91061|Bacilli C reductase XK27_09615 - - ko:K19784 - - - - ko00000 - - - FMN_red,PAS_10 BJHFPPGC_01568 1046629.Ssal_00181 3.33e-140 396.0 COG0431@1|root,COG0431@2|Bacteria 2|Bacteria S FMN reductase (NADPH) activity XK27_09620 - - - - - - - - - - - FMN_red BJHFPPGC_01569 264199.stu1824 5.55e-100 290.0 COG0756@1|root,COG0756@2|Bacteria,1V6HX@1239|Firmicutes,4HIZ3@91061|Bacilli 91061|Bacilli F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA dut - 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase BJHFPPGC_01570 1095738.HMPREF1047_1312 1.05e-96 282.0 COG1335@1|root,COG1335@2|Bacteria 2|Bacteria Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides - - 3.5.1.19 ko:K08281 ko00760,ko01100,map00760,map01100 - R01268 RC00100 ko00000,ko00001,ko01000 - - - Isochorismatase BJHFPPGC_01571 1046629.Ssal_00184 2.63e-285 781.0 COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,4H9YC@91061|Bacilli 91061|Bacilli O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA - - ko:K04485 - - - - ko00000,ko03400 - - - AAA_25,ATPase,ChlI BJHFPPGC_01572 1046629.Ssal_00185 4.83e-162 454.0 COG2013@1|root,COG2013@2|Bacteria,1V6BD@1239|Firmicutes,4HIAR@91061|Bacilli 91061|Bacilli S Mitochondrial biogenesis AIM24 - - - - - - - - - - - - AIM24 BJHFPPGC_01573 1046629.Ssal_00186 3.22e-114 327.0 COG0288@1|root,COG0288@2|Bacteria,1V0TA@1239|Firmicutes,4HB9V@91061|Bacilli 91061|Bacilli P Reversible hydration of carbon dioxide cah - 4.2.1.1 ko:K01673 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Pro_CA BJHFPPGC_01574 1046629.Ssal_00187 4.66e-66 202.0 2DSU9@1|root,33HF9@2|Bacteria,1VNK9@1239|Firmicutes 1239|Firmicutes S Protein of unknown function (DUF3397) - - - - - - - - - - - - DUF3397 BJHFPPGC_01575 1046629.Ssal_00188 1.69e-93 273.0 COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,4HFQ0@91061|Bacilli 91061|Bacilli J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors rplK GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02867 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L11,Ribosomal_L11_N BJHFPPGC_01576 1046629.Ssal_00189 1.37e-155 438.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,4HAK4@91061|Bacilli 91061|Bacilli J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release rplA GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02863 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L1 BJHFPPGC_01577 1046629.Ssal_00190 0.0 1268.0 COG4166@1|root,COG4166@2|Bacteria,1TQVS@1239|Firmicutes,4HCCB@91061|Bacilli 91061|Bacilli E ABC transporter, substrate-binding protein, family 5 amiA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 BJHFPPGC_01578 904306.HMPREF9192_2057 0.0 944.0 COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,4HAKH@91061|Bacilli 91061|Bacilli J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:2001065 6.1.1.24 ko:K09698 ko00970,ko01100,map00970,map01100 M00360 R03651,R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iSB619.SA_RS02860 tRNA-synt_1c BJHFPPGC_01579 1046629.Ssal_00192 1.6e-290 796.0 COG3290@1|root,COG3290@2|Bacteria,1UYTM@1239|Firmicutes,4IPJ9@91061|Bacilli 91061|Bacilli T signal transduction protein with a C-terminal ATPase domain - - 2.7.13.3 ko:K07706 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c_5 BJHFPPGC_01580 1046629.Ssal_00193 8.94e-195 542.0 COG3290@1|root,COG3290@2|Bacteria 2|Bacteria T protein histidine kinase activity hpk9 - 2.7.13.3 ko:K07706 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c_5,PAS_9 BJHFPPGC_01581 435842.HMPREF0848_01856 1.16e-260 719.0 COG3290@1|root,COG3290@2|Bacteria 2|Bacteria T protein histidine kinase activity hpk9 - 2.7.13.3 ko:K07706 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c_5,PAS_9 BJHFPPGC_01582 435842.HMPREF0848_01857 8.46e-285 781.0 COG3290@1|root,COG3290@2|Bacteria 2|Bacteria T protein histidine kinase activity fasC - - - - - - - - - - - HATPase_c_5,PAS_9 BJHFPPGC_01583 435842.HMPREF0848_01858 3.78e-167 468.0 COG3279@1|root,COG3279@2|Bacteria,1V392@1239|Firmicutes,4HHAI@91061|Bacilli 91061|Bacilli KT Response regulator of the LytR AlgR family fasA - - ko:K07707 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg BJHFPPGC_01584 1046629.Ssal_00198 2.89e-293 800.0 COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,4HA1E@91061|Bacilli 91061|Bacilli E Belongs to the argininosuccinate synthase family. Type 1 subfamily argG GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 - - iSB619.SA_RS04675 Arginosuc_synth BJHFPPGC_01585 1046629.Ssal_00199 0.0 907.0 COG0165@1|root,COG0165@2|Bacteria,1TNZ6@1239|Firmicutes,4HB24@91061|Bacilli 91061|Bacilli E Argininosuccinate lyase argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ASL_C2,Lyase_1 BJHFPPGC_01586 264199.stu1811 9.69e-72 216.0 COG0594@1|root,COG0594@2|Bacteria,1VA78@1239|Firmicutes,4HKG6@91061|Bacilli 91061|Bacilli J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme rnpA GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0031123,GO:0031404,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 ko:K03536 - - - - ko00000,ko01000,ko03016 - - - Ribonuclease_P BJHFPPGC_01587 1046629.Ssal_00201 2.01e-177 496.0 COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,4HB3J@91061|Bacilli 91061|Bacilli U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins yidC GO:0005575,GO:0008150,GO:0009653,GO:0009987,GO:0016020,GO:0030154,GO:0030435,GO:0032502,GO:0043934,GO:0048646,GO:0048856,GO:0048869 - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP BJHFPPGC_01588 1046629.Ssal_00202 1.81e-215 598.0 COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,4HHHU@91061|Bacilli 91061|Bacilli S RNA-binding protein jag - - ko:K06346 - - - - ko00000 - - - Jag_N,KH_4,R3H BJHFPPGC_01589 1046629.Ssal_00203 3.22e-127 363.0 COG1309@1|root,COG1309@2|Bacteria,1V0VT@1239|Firmicutes,4HPD3@91061|Bacilli 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - TetR_N,WHG BJHFPPGC_01590 1046629.Ssal_00204 9.27e-127 361.0 COG2249@1|root,COG2249@2|Bacteria,1V59U@1239|Firmicutes,4HHZC@91061|Bacilli 91061|Bacilli S NADPH-quinone reductase (modulator of drug activity B) - - 1.6.5.2 ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 - R02964,R03643,R03816 RC00819 ko00000,ko00001,ko01000 - - - Flavodoxin_2 BJHFPPGC_01591 1046629.Ssal_00205 4.62e-20 80.5 COG0230@1|root,COG0230@2|Bacteria 2|Bacteria J Ribosomal protein L34 rpmH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02914 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L34 BJHFPPGC_01592 1046629.Ssal_00206 3.32e-287 783.0 COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,4HCNM@91061|Bacilli 91061|Bacilli F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) tgt GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 ko:K00773 - - R03789,R10209 RC00063 ko00000,ko01000,ko03016 - - - TGT BJHFPPGC_01594 1046629.Ssal_00210 8.62e-66 201.0 COG0526@1|root,COG0526@2|Bacteria 2|Bacteria CO cell redox homeostasis bta - 1.8.1.8 ko:K03671,ko:K03672 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko01000,ko03110 - - - Thioredoxin,TraF BJHFPPGC_01595 435842.HMPREF0848_01462 7.43e-77 231.0 COG0824@1|root,COG0824@2|Bacteria,1VAGM@1239|Firmicutes,4HIVC@91061|Bacilli 91061|Bacilli L thioesterase yneP - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT,4HBT_2 BJHFPPGC_01596 1046629.Ssal_00214 2.39e-181 505.0 COG2110@1|root,COG2110@2|Bacteria,1TQSZ@1239|Firmicutes,4HCXD@91061|Bacilli 91061|Bacilli S Macro domain protein - - - - - - - - - - - - Macro BJHFPPGC_01597 904306.HMPREF9192_0562 3.11e-67 204.0 COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,4HKKX@91061|Bacilli 91061|Bacilli O Belongs to the thioredoxin family trxA - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin BJHFPPGC_01598 1046629.Ssal_00216 4.62e-92 270.0 COG1832@1|root,COG1832@2|Bacteria,1V7C7@1239|Firmicutes,4HIZT@91061|Bacilli 91061|Bacilli S CoA-binding protein yneT - - ko:K06929 - - - - ko00000 - - - CoA_binding_2 BJHFPPGC_01599 1046629.Ssal_00217 4.36e-181 504.0 COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,4HA74@91061|Bacilli 91061|Bacilli L Hydrolase, tatd tatD GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase BJHFPPGC_01600 1046629.Ssal_00218 2.03e-125 357.0 COG1658@1|root,COG1658@2|Bacteria,1V3K3@1239|Firmicutes,4HH5Y@91061|Bacilli 91061|Bacilli J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step rnmV GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043822,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 3.1.26.8 ko:K05985 - - - - ko00000,ko01000 - - - DUF4093,Toprim,Toprim_4 BJHFPPGC_01601 1046629.Ssal_00219 8.34e-197 546.0 COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,4HA4R@91061|Bacilli 91061|Bacilli J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits ksgA GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 ko:K02528 - - R10716 RC00003,RC03257 ko00000,ko01000,ko03009 - - - RrnaAD BJHFPPGC_01603 1046629.Ssal_00220 1.46e-206 571.0 COG1162@1|root,COG1162@2|Bacteria,1TPSQ@1239|Firmicutes,4HA9W@91061|Bacilli 91061|Bacilli G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase,RsgA_N BJHFPPGC_01604 904306.HMPREF9192_0569 3.29e-154 433.0 COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,4H9RW@91061|Bacilli 91061|Bacilli G Belongs to the ribulose-phosphate 3-epimerase family rpe GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim BJHFPPGC_01605 1046629.Ssal_00222 4.01e-146 412.0 COG1564@1|root,COG1564@2|Bacteria,1VA0W@1239|Firmicutes,4HHS1@91061|Bacilli 91061|Bacilli H thiamine pyrophosphokinase thiN - 2.7.6.2 ko:K00949 ko00730,ko01100,map00730,map01100 - R00619 RC00002,RC00017 ko00000,ko00001,ko01000 - - - TPK_B1_binding,TPK_catalytic BJHFPPGC_01606 1046629.Ssal_00223 1.2e-224 628.0 COG1322@1|root,COG1322@2|Bacteria,1TPWI@1239|Firmicutes,4HE2N@91061|Bacilli 91061|Bacilli S RmuC domain protein rmuC - - ko:K09760 - - - - ko00000 - - - RmuC BJHFPPGC_01607 1046629.Ssal_00224 6.86e-228 627.0 COG3481@1|root,COG3481@2|Bacteria,1TPIU@1239|Firmicutes,4HB1M@91061|Bacilli 91061|Bacilli S 3'-5' exoribonuclease yhaM yhaM GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K03698 - - - - ko00000,ko01000,ko03019 - - - HD,tRNA_anti-codon BJHFPPGC_01608 904306.HMPREF9192_0573 7.91e-184 512.0 COG0503@1|root,COG0503@2|Bacteria,1TPN9@1239|Firmicutes,4HB8I@91061|Bacilli 91061|Bacilli F operon repressor purR - - ko:K09685 - - - - ko00000,ko03000 - - - Pribosyltran,PuR_N BJHFPPGC_01609 1046629.Ssal_00226 4.89e-91 266.0 COG0048@1|root,COG0048@2|Bacteria,1V1FJ@1239|Firmicutes,4HFMZ@91061|Bacilli 91061|Bacilli J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit rpsL GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02950 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosom_S12_S23 BJHFPPGC_01610 1046629.Ssal_00227 4.66e-105 303.0 COG0049@1|root,COG0049@2|Bacteria,1V1GG@1239|Firmicutes,4H9PA@91061|Bacilli 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02992 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S7 BJHFPPGC_01611 1046629.Ssal_00229 0.0 1360.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,4HAB8@91061|Bacilli 91061|Bacilli J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome fusA - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 BJHFPPGC_01612 1005705.HMPREF9967_0458 4.47e-231 637.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,4H9NS@91061|Bacilli,43FFT@68892|Streptococcus infantis 91061|Bacilli C Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain gap GO:0000166,GO:0002020,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0019362,GO:0019637,GO:0019674,GO:0019899,GO:0034641,GO:0036094,GO:0043891,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0097159,GO:1901265,GO:1901360,GO:1901363,GO:1901564 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N BJHFPPGC_01613 1046629.Ssal_00231 1.07e-146 415.0 28KD0@1|root,2Z9ZS@2|Bacteria,1V2YR@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - BJHFPPGC_01614 1046629.Ssal_00232 3.32e-283 774.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,4H9R3@91061|Bacilli 91061|Bacilli F Belongs to the phosphoglycerate kinase family pgk GO:0001871,GO:0002020,GO:0003674,GO:0003824,GO:0004618,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009893,GO:0009986,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019222,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030162,GO:0030193,GO:0030195,GO:0030246,GO:0030247,GO:0030312,GO:0031323,GO:0031325,GO:0032101,GO:0032102,GO:0032268,GO:0032270,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043532,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0045862,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050818,GO:0050819,GO:0050878,GO:0051171,GO:0051173,GO:0051186,GO:0051188,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051917,GO:0051919,GO:0055086,GO:0060255,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070613,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0080134,GO:0090407,GO:1900046,GO:1900047,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903034,GO:1903035,GO:1903317,GO:1903319,GO:2001065 2.7.2.3 ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01512 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000,ko04147 - - iSB619.SA_RS04145 PGK BJHFPPGC_01615 1046629.Ssal_00233 1.03e-111 321.0 COG4129@1|root,COG4129@2|Bacteria,1VAJG@1239|Firmicutes,4HKDZ@91061|Bacilli 91061|Bacilli S Fusaric acid resistance protein-like - - - - - - - - - - - - ArAE_1,FUSC_2 BJHFPPGC_01616 435842.HMPREF0848_01442 9.18e-83 244.0 COG0789@1|root,COG0789@2|Bacteria,1V6JE@1239|Firmicutes,4HKM6@91061|Bacilli 91061|Bacilli K Transcriptional regulator glnR GO:0003674,GO:0005488,GO:0005515,GO:0006082,GO:0006355,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016053,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903506,GO:2000112,GO:2001141 - ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000,ko03000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - MerR_1 BJHFPPGC_01617 1046629.Ssal_00235 0.0 905.0 COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,4HACE@91061|Bacilli 91061|Bacilli E glutamine synthetase glnA - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N BJHFPPGC_01618 435842.HMPREF0848_01440 1.7e-147 415.0 COG3942@1|root,COG3942@2|Bacteria,1V8WM@1239|Firmicutes,4HIMT@91061|Bacilli 91061|Bacilli M CHAP domain protein sle1 - 3.5.1.28 ko:K22409 - - - - ko00000,ko01000 - CBM50 - CHAP,LysM BJHFPPGC_01619 435842.HMPREF0848_01439 0.0 1108.0 COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4HAAP@91061|Bacilli 91061|Bacilli S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay rnjA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004534,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008409,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360 - ko:K12574 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - Lactamase_B,RMMBL BJHFPPGC_01620 1046629.Ssal_00239 4.54e-45 145.0 COG5503@1|root,COG5503@2|Bacteria,1VEI7@1239|Firmicutes,4HNSK@91061|Bacilli 91061|Bacilli S Belongs to the UPF0356 family ykzG - - - - - - - - - - - DUF1447 BJHFPPGC_01621 435842.HMPREF0848_01437 1.73e-148 420.0 COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,4HHD7@91061|Bacilli 91061|Bacilli O COG1214, inactive homolog of metal-dependent proteases yeaZ GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 ko:K01409,ko:K14742 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 BJHFPPGC_01622 435842.HMPREF0848_01436 8.68e-95 277.0 COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,4HP50@91061|Bacilli 91061|Bacilli K This enzyme acetylates the N-terminal alanine of ribosomal protein S18 rimI - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_7 BJHFPPGC_01623 1046629.Ssal_00242 7.79e-237 652.0 COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,4HANB@91061|Bacilli 91061|Bacilli O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction tsaD GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 ko:K01409 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 BJHFPPGC_01624 435842.HMPREF0848_01434 1.7e-146 414.0 COG1296@1|root,COG1296@2|Bacteria,1V64T@1239|Firmicutes,4HH44@91061|Bacilli 91061|Bacilli E AzlC protein XK27_12120 - - - - - - - - - - - AzlC BJHFPPGC_01625 435842.HMPREF0848_01433 1.14e-62 192.0 COG4392@1|root,COG4392@2|Bacteria,1VH9Q@1239|Firmicutes,4HRBI@91061|Bacilli 91061|Bacilli S branched-chain amino acid - - - - - - - - - - - - AzlD BJHFPPGC_01626 1046629.Ssal_00246 0.0 1587.0 COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,4HATQ@91061|Bacilli 91061|Bacilli L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity recD2 - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,HHH_5,UvrD_C_2 BJHFPPGC_01627 904306.HMPREF9192_0591 6.48e-136 386.0 COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,4HMGQ@91061|Bacilli 91061|Bacilli U Belongs to the peptidase S26 family lepB - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 BJHFPPGC_01628 1046629.Ssal_00249 2.07e-196 546.0 COG1039@1|root,COG1039@2|Bacteria,1TQBE@1239|Firmicutes,4H9QR@91061|Bacilli 91061|Bacilli L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhC GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03471 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DUF3378,RNase_HII BJHFPPGC_01629 1302863.I872_01550 7.01e-36 124.0 COG3027@1|root,COG3027@2|Bacteria,1VFZS@1239|Firmicutes,4HP4T@91061|Bacilli 91061|Bacilli D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division - - - ko:K09888 - - - - ko00000,ko03036 - - - ZapA BJHFPPGC_01630 1046629.Ssal_00251 3.65e-116 333.0 COG1286@1|root,COG1286@2|Bacteria 2|Bacteria S toxin biosynthetic process cvpA GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016020,GO:0019748,GO:0044237,GO:0044249,GO:0044464,GO:0044550,GO:0071944 - ko:K03558 - - - - ko00000 - - - Colicin_V,Trypsin_2 BJHFPPGC_01631 435842.HMPREF0848_01427 0.0 1477.0 COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,4H9NZ@91061|Bacilli 91061|Bacilli L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity mutS2 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K07456 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_V,Smr BJHFPPGC_01632 435842.HMPREF0848_01419 0.0 1681.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,4H9S7@91061|Bacilli 91061|Bacilli L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A BJHFPPGC_01634 397288.C806_03616 6.52e-49 160.0 2DZDF@1|root,32V7U@2|Bacteria,1VB8V@1239|Firmicutes,24KMP@186801|Clostridia,27ME7@186928|unclassified Lachnospiraceae 186801|Clostridia - - - - - - - - - - - - - - - BJHFPPGC_01637 1046629.Ssal_00266 3.97e-276 755.0 COG1194@1|root,COG1194@2|Bacteria,1TPUT@1239|Firmicutes,4H9UM@91061|Bacilli 91061|Bacilli L A G-specific adenine glycosylase mutY - - ko:K03575 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD,NUDIX_4 BJHFPPGC_01638 1214166.ALLG01000021_gene137 4.49e-52 180.0 2BJFN@1|root,32DS8@2|Bacteria,1U8WY@1239|Firmicutes,4IIVI@91061|Bacilli,1WSBS@1307|Streptococcus suis 91061|Bacilli - - XK27_05745 - - - - - - - - - - - - BJHFPPGC_01639 904306.HMPREF9192_0608 1.88e-62 191.0 COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,4HKHD@91061|Bacilli 91061|Bacilli J Binds together with S18 to 16S ribosomal RNA rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - ko:K02990 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S6 BJHFPPGC_01640 904306.HMPREF9192_0609 4.18e-118 338.0 COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,4HH8I@91061|Bacilli 91061|Bacilli L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB BJHFPPGC_01641 1046629.Ssal_00271 4.1e-47 151.0 COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,4HKCC@91061|Bacilli 91061|Bacilli J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit rpsR GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02963 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S18 BJHFPPGC_01643 1046629.Ssal_00273 1.14e-156 439.0 COG4858@1|root,COG4858@2|Bacteria,1VF5N@1239|Firmicutes,4HMVT@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF1129) XK27_01040 - - - - - - - - - - - DUF1129 BJHFPPGC_01644 435842.HMPREF0848_01411 2.34e-215 595.0 COG0598@1|root,COG0598@2|Bacteria,1TPI8@1239|Firmicutes,4HE7S@91061|Bacilli 91061|Bacilli P COG0598 Mg2 and Co2 transporters corA - - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - - CorA BJHFPPGC_01645 435842.HMPREF0848_01410 0.0 1848.0 COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,4HAW9@91061|Bacilli 91061|Bacilli L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran BJHFPPGC_01649 1123311.KB904456_gene755 2.49e-40 150.0 2DWQH@1|root,341F6@2|Bacteria,1W6SH@1239|Firmicutes,4HX74@91061|Bacilli 91061|Bacilli - - blpT - - - - - - - - - - - Thioredoxin BJHFPPGC_01650 1046629.Ssal_00280 1.69e-255 700.0 COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,4HAT7@91061|Bacilli 91061|Bacilli E Belongs to the peptidase M24B family pepP - 3.4.11.9,3.4.13.9 ko:K01262,ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 BJHFPPGC_01651 1046629.Ssal_00281 3.59e-111 318.0 COG2131@1|root,COG2131@2|Bacteria,1V8V0@1239|Firmicutes,4IQZA@91061|Bacilli 91061|Bacilli F ComE operon protein 2 comEB - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 BJHFPPGC_01652 1046629.Ssal_00282 1.22e-126 360.0 COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,4H9YX@91061|Bacilli 91061|Bacilli J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C BJHFPPGC_01653 1046629.Ssal_00283 7.41e-80 238.0 COG1302@1|root,COG1302@2|Bacteria,1V4IC@1239|Firmicutes,4HJ7T@91061|Bacilli 91061|Bacilli S protein conserved in bacteria WQ51_04310 - - ko:K10947 - - - - ko00000,ko03000 - - - Asp23 BJHFPPGC_01654 1046629.Ssal_00284 1.09e-95 279.0 COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,4HKMU@91061|Bacilli 91061|Bacilli K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons nusB - - ko:K03625 - - - - ko00000,ko03009,ko03021 - - - NusB BJHFPPGC_01655 435842.HMPREF0848_01398 1.28e-227 627.0 COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes 1239|Firmicutes K Transcriptional regulator scrR - - ko:K03484 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 BJHFPPGC_01656 1046629.Ssal_00286 0.0 993.0 COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,4H9Y7@91061|Bacilli 91061|Bacilli G invertase scrB - 3.2.1.26 ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00801,R00802,R02410,R03635,R03921,R06088 RC00028,RC00077 ko00000,ko00001,ko01000 - GH32 - Glyco_hydro_32C,Glyco_hydro_32N BJHFPPGC_01657 1046629.Ssal_00287 0.0 1205.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli 91061|Bacilli G pts system scrA - 2.7.1.211 ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 M00269 R00811 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC BJHFPPGC_01658 904306.HMPREF9192_0630 1.95e-219 604.0 COG1940@1|root,COG1940@2|Bacteria,1TQU4@1239|Firmicutes,4HA1C@91061|Bacilli 91061|Bacilli GK Fructokinase scrK - 2.7.1.4 ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 - R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - - ROK BJHFPPGC_01659 1046629.Ssal_00290 2.52e-240 659.0 COG1482@1|root,COG1482@2|Bacteria,1VRGI@1239|Firmicutes,4HBFW@91061|Bacilli 91061|Bacilli G mannose-6-phosphate isomerase manA - 5.3.1.8 ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01819 RC00376 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU12020 PMI_typeI BJHFPPGC_01661 1046629.Ssal_00292 0.0 1653.0 COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,4HA22@91061|Bacilli 91061|Bacilli U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW BJHFPPGC_01662 904306.HMPREF9192_0634 3.37e-250 686.0 COG0722@1|root,COG0722@2|Bacteria,1TQI4@1239|Firmicutes 1239|Firmicutes E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) aroH - 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - iHN637.CLJU_RS07240 DAHP_synth_1 BJHFPPGC_01663 1046629.Ssal_00295 2.59e-249 684.0 COG0722@1|root,COG0722@2|Bacteria,1TQI4@1239|Firmicutes 1239|Firmicutes E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) aroG - 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - iHN637.CLJU_RS07240 DAHP_synth_1 BJHFPPGC_01664 1046629.Ssal_00296 4.16e-78 232.0 COG0736@1|root,COG0736@2|Bacteria,1VA0T@1239|Firmicutes,4HKBI@91061|Bacilli 91061|Bacilli I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein acpS - 2.7.8.7 ko:K00997 ko00770,map00770 - R01625 RC00002 ko00000,ko00001,ko01000 - - iYO844.BSU04620 ACPS BJHFPPGC_01665 1046629.Ssal_00297 5.74e-245 675.0 COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,4HA95@91061|Bacilli 91061|Bacilli E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1,5.1.1.5 ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N BJHFPPGC_01666 435842.HMPREF0848_01388 0.0 1300.0 COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,4HAWN@91061|Bacilli 91061|Bacilli L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge BJHFPPGC_01670 1046629.Ssal_00306 3.36e-42 138.0 COG3655@1|root,COG3655@2|Bacteria,1VESP@1239|Firmicutes 1239|Firmicutes K Transcriptional regulator yozG - - ko:K07727 - - - - ko00000,ko03000 - - - HTH_26 BJHFPPGC_01672 1046629.Ssal_00308 2.2e-219 606.0 COG0252@1|root,COG0252@2|Bacteria,1TPP9@1239|Firmicutes,4H9YJ@91061|Bacilli 91061|Bacilli EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D ansB - 3.5.1.1 ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 - R00485 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Asparaginase BJHFPPGC_01673 904306.HMPREF9192_0643 0.0 899.0 COG0561@1|root,COG4696@1|root,COG0561@2|Bacteria,COG4696@2|Bacteria,1TSZZ@1239|Firmicutes,4HB54@91061|Bacilli 91061|Bacilli S hydrolases of the HAD superfamily - - - - - - - - - - - - Hydrolase_3,PRA-PH BJHFPPGC_01674 1046629.Ssal_00310 6.58e-166 477.0 COG3064@1|root,COG3064@2|Bacteria,1VK5M@1239|Firmicutes,4HS44@91061|Bacilli 91061|Bacilli M Membrane yebC - - - - - - - - - - - zf-ribbon_3,zinc_ribbon_2 BJHFPPGC_01675 1046629.Ssal_00311 0.0 1068.0 COG4640@1|root,COG4640@2|Bacteria 2|Bacteria KT response to antibiotic - - - - - - - - - - - - - BJHFPPGC_01676 322159.STER_1684 5.33e-98 285.0 COG3279@1|root,COG3279@2|Bacteria,1VBF7@1239|Firmicutes,4HMZX@91061|Bacilli 91061|Bacilli K LytTr DNA-binding domain - - - - - - - - - - - - LytTR BJHFPPGC_01677 322159.STER_1683 4.09e-154 434.0 COG4758@1|root,COG4758@2|Bacteria,1VGSF@1239|Firmicutes,4IRBC@91061|Bacilli 91061|Bacilli S membrane - - - - - - - - - - - - - BJHFPPGC_01678 888746.HMPREF9180_1370 6.01e-245 673.0 COG1619@1|root,COG1619@2|Bacteria,1TRBB@1239|Firmicutes,4HDUZ@91061|Bacilli 91061|Bacilli V LD-carboxypeptidase mccF - - - - - - - - - - - Peptidase_S66 BJHFPPGC_01679 1046629.Ssal_00314 0.0 1019.0 COG0443@1|root,COG0443@2|Bacteria,1TSUC@1239|Firmicutes 1239|Firmicutes O MreB/Mbl protein - - - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 BJHFPPGC_01681 1046629.Ssal_00316 3.41e-186 517.0 COG1131@1|root,COG1131@2|Bacteria,1V0ED@1239|Firmicutes 1239|Firmicutes V Psort location CytoplasmicMembrane, score - - - ko:K21397 - - - - ko00000,ko02000 3.A.1 - - ABC2_membrane,ABC_tran,FHA BJHFPPGC_01684 365659.smi_1723 3.63e-15 87.0 2DKFM@1|root,309CC@2|Bacteria,1U4TK@1239|Firmicutes,4IEJ2@91061|Bacilli,2TQA8@28037|Streptococcus mitis 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_01685 1046629.Ssal_00320 3.9e-287 787.0 COG3290@1|root,COG3290@2|Bacteria 2|Bacteria T protein histidine kinase activity dcuS GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016020,GO:0016021,GO:0016043,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0023014,GO:0023052,GO:0031224,GO:0031226,GO:0031323,GO:0031326,GO:0035556,GO:0036211,GO:0042802,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051259,GO:0051260,GO:0051716,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0140096,GO:1901564,GO:1903506,GO:2000112,GO:2001141 2.7.13.3 ko:K02476,ko:K07701,ko:K07706,ko:K11614 ko02020,ko02024,map02020,map02024 M00488,M00490,M00495 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,PAS,SPOB_a,sCache_3_2 BJHFPPGC_01686 1046629.Ssal_00321 6.12e-297 814.0 COG3290@1|root,COG3290@2|Bacteria 2|Bacteria T protein histidine kinase activity - - 2.7.13.3 ko:K07706 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c_5,PAS_9 BJHFPPGC_01687 1046629.Ssal_00322 0.0 2100.0 COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,4HAY6@91061|Bacilli 91061|Bacilli L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination rexB GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004527,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.6.4.12 ko:K16899 - - - - ko00000,ko01000,ko03400 - - - Exonuc_V_gamma,PDDEXK_1,UvrD_C BJHFPPGC_01688 1046629.Ssal_00325 0.0 2319.0 COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,4HA64@91061|Bacilli 91061|Bacilli L ATP-dependent helicase nuclease subunit A addA GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 3.6.4.12 ko:K16898 - - - - ko00000,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C BJHFPPGC_01689 1046629.Ssal_00984 2.23e-110 319.0 COG1943@1|root,COG1943@2|Bacteria,1TSQ0@1239|Firmicutes,4HDZ0@91061|Bacilli 91061|Bacilli L COG1943 Transposase and inactivated derivatives isplu5A - - ko:K07491 - - - - ko00000 - - - Y1_Tnp BJHFPPGC_01690 1046629.Ssal_00327 4.24e-162 455.0 COG1811@1|root,COG1811@2|Bacteria,1TQWV@1239|Firmicutes,4HEYY@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF554) - - - ko:K07150 - - - - ko00000 - - - DUF554 BJHFPPGC_01691 1046629.Ssal_00328 4.29e-171 478.0 COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,4HCEU@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein ecsA_2 - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran BJHFPPGC_01692 1046629.Ssal_00329 0.0 983.0 28MBB@1|root,2ZAPV@2|Bacteria,1TSZA@1239|Firmicutes,4HDKH@91061|Bacilli 91061|Bacilli - - XK27_00765 - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - - BJHFPPGC_01694 1046629.Ssal_00725 5.76e-287 824.0 COG5263@1|root,COG5263@2|Bacteria 2|Bacteria S dextransucrase activity - - - - - - - - - - - - CW_binding_1,NLPC_P60,PG_binding_1 BJHFPPGC_01695 435842.HMPREF0848_00996 0.0 1629.0 COG5263@1|root,COG5263@2|Bacteria,1V0PX@1239|Firmicutes 1239|Firmicutes M Putative cell wall binding repeat tcdB - - ko:K11063 ko02024,map02024 - - - ko00000,ko00001,ko02042 - - - CW_binding_1,LRR_5,NLPC_P60,Peptidase_C80,TcdA_TcdB,TcdA_TcdB_pore,TcdB_N BJHFPPGC_01696 1046629.Ssal_00726 0.0 1298.0 COG5263@1|root,COG5263@2|Bacteria 2|Bacteria S dextransucrase activity - - - - - - - - - - - - CW_binding_1,NLPC_P60,PG_binding_1 BJHFPPGC_01697 1046629.Ssal_00725 3.6e-242 717.0 COG5263@1|root,COG5263@2|Bacteria 2|Bacteria S dextransucrase activity - - - - - - - - - - - - CW_binding_1,NLPC_P60,PG_binding_1 BJHFPPGC_01698 1046629.Ssal_00728 0.0 1129.0 COG5263@1|root,COG5263@2|Bacteria 2|Bacteria S dextransucrase activity - - - - - - - - - - - - CW_binding_1,NLPC_P60,PG_binding_1 BJHFPPGC_01699 1046629.Ssal_00730 1.68e-199 553.0 COG0214@1|root,COG0214@2|Bacteria,1TPSZ@1239|Firmicutes,4H9RA@91061|Bacilli 91061|Bacilli H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively pdxS GO:0003674,GO:0005488,GO:0005515,GO:0042802 4.3.3.6 ko:K06215 ko00750,map00750 - R07456 RC00010,RC01783,RC03043 ko00000,ko00001,ko01000 - - - SOR_SNZ BJHFPPGC_01700 1046629.Ssal_00731 5.27e-40 137.0 COG0311@1|root,COG0311@2|Bacteria,1V3I6@1239|Firmicutes,4HFSZ@91061|Bacilli 91061|Bacilli H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS pdxT GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 ko:K08681 ko00750,map00750 - R07456 RC00010,RC01783,RC03043 ko00000,ko00001,ko01000 - - - SNO BJHFPPGC_01701 1046629.Ssal_00731 5.85e-57 181.0 COG0311@1|root,COG0311@2|Bacteria,1V3I6@1239|Firmicutes,4HFSZ@91061|Bacilli 91061|Bacilli H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS pdxT GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 ko:K08681 ko00750,map00750 - R07456 RC00010,RC01783,RC03043 ko00000,ko00001,ko01000 - - - SNO BJHFPPGC_01702 1046629.Ssal_00732 0.0 1429.0 COG5263@1|root,COG5263@2|Bacteria 2|Bacteria S dextransucrase activity - - - - - - - - - - - - CW_binding_1,NLPC_P60,PG_binding_1 BJHFPPGC_01703 1046629.Ssal_00734 9.15e-103 352.0 COG5263@1|root,COG5263@2|Bacteria,1V0PX@1239|Firmicutes 1239|Firmicutes M Putative cell wall binding repeat tcdB - - ko:K11063 ko02024,map02024 - - - ko00000,ko00001,ko02042 - - - CW_binding_1,LRR_5,NLPC_P60,Peptidase_C80,TcdA_TcdB,TcdA_TcdB_pore,TcdB_N BJHFPPGC_01704 1046629.Ssal_00735 0.0 913.0 COG5263@1|root,COG5263@2|Bacteria 2|Bacteria S dextransucrase activity - - - - - - - - - - - - CW_binding_1,NLPC_P60,PG_binding_1 BJHFPPGC_01705 1046629.Ssal_00735 0.0 1302.0 COG5263@1|root,COG5263@2|Bacteria 2|Bacteria S dextransucrase activity - - - - - - - - - - - - CW_binding_1,NLPC_P60,PG_binding_1 BJHFPPGC_01706 1046629.Ssal_00736 0.0 1476.0 COG5263@1|root,COG5263@2|Bacteria 2|Bacteria S dextransucrase activity - - - - - - - - - - - - CW_binding_1,NLPC_P60,PG_binding_1 BJHFPPGC_01707 1046629.Ssal_00737 0.0 1719.0 COG5263@1|root,COG5263@2|Bacteria 2|Bacteria S dextransucrase activity - - - - - - - - - - - - CW_binding_1,NLPC_P60,PG_binding_1 BJHFPPGC_01708 1046629.Ssal_00738 0.0 2632.0 COG0366@1|root,COG5263@1|root,COG0366@2|Bacteria,COG5263@2|Bacteria,1VQXK@1239|Firmicutes,4HEIA@91061|Bacilli 91061|Bacilli M KxYKxGKxW signal domain protein - GO:0005575,GO:0005576 2.4.1.5 ko:K00689 ko00500,ko02020,map00500,map02020 - R02120,R06066 RC00028 ko00000,ko00001,ko01000 - GH13 - Big_2,CW_binding_1,Glyco_hydro_70 BJHFPPGC_01709 1046629.Ssal_00740 0.0 1085.0 COG5263@1|root,COG5263@2|Bacteria 2|Bacteria S dextransucrase activity - - - - - - - - - - - - CW_binding_1,NLPC_P60,PG_binding_1 BJHFPPGC_01711 1046629.Ssal_00742 0.0 2840.0 COG0366@1|root,COG5263@1|root,COG0366@2|Bacteria,COG5263@2|Bacteria,1VQXK@1239|Firmicutes,4HEIA@91061|Bacilli 91061|Bacilli M KxYKxGKxW signal domain protein - GO:0005575,GO:0005576 2.4.1.5 ko:K00689 ko00500,ko02020,map00500,map02020 - R02120,R06066 RC00028 ko00000,ko00001,ko01000 - GH13 - Big_2,CW_binding_1,Glyco_hydro_70 BJHFPPGC_01712 1069533.Sinf_1729 1.72e-10 60.5 2EGBF@1|root,33A3A@2|Bacteria,1VP2X@1239|Firmicutes,4HS3U@91061|Bacilli 91061|Bacilli S Enterocin A Immunity - - - - - - - - - - - - EntA_Immun BJHFPPGC_01713 1046629.Ssal_00744 3.82e-137 392.0 COG4377@1|root,COG4377@2|Bacteria 2|Bacteria S Putative membrane peptidase family (DUF2324) yhfC - - - - - - - - - - - DUF2324 BJHFPPGC_01714 1046629.Ssal_00745 1.21e-58 181.0 COG0640@1|root,COG0640@2|Bacteria,1UKJV@1239|Firmicutes,4ITJ6@91061|Bacilli 91061|Bacilli K helix_turn_helix, Arsenical Resistance Operon Repressor - - - - - - - - - - - - HTH_20 BJHFPPGC_01715 1215915.BN193_03000 1.19e-13 73.9 COG5658@1|root,COG5658@2|Bacteria,1VBIT@1239|Firmicutes,4HJDZ@91061|Bacilli 91061|Bacilli S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane yvaZ GO:0008150,GO:0009636,GO:0042221,GO:0050896 - - - - - - - - - - DUF1648,SdpI BJHFPPGC_01718 1046629.Ssal_00750 0.0 1302.0 COG3590@1|root,COG3590@2|Bacteria,1TQTA@1239|Firmicutes,4HDSF@91061|Bacilli 91061|Bacilli O Peptidase family M13 pepO - - ko:K07386 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M13,Peptidase_M13_N BJHFPPGC_01719 927666.SOR_0713 3.07e-45 148.0 2DKHV@1|root,309HT@2|Bacteria,1U54E@1239|Firmicutes,4I1BW@91061|Bacilli 91061|Bacilli S Immunity protein 41 - - - - - - - - - - - - Imm41 BJHFPPGC_01720 999425.HMPREF9186_00431 1.6e-170 479.0 COG0639@1|root,COG0639@2|Bacteria,1VDTG@1239|Firmicutes,4HKC1@91061|Bacilli 91061|Bacilli T Ser Thr phosphatase family protein - - - - - - - - - - - - Metallophos_2 BJHFPPGC_01721 1046629.Ssal_00755 0.0 2135.0 COG5263@1|root,COG5263@2|Bacteria,1V0PX@1239|Firmicutes 1239|Firmicutes M Putative cell wall binding repeat tcdB - - ko:K11063 ko02024,map02024 - - - ko00000,ko00001,ko02042 - - - CW_binding_1,LRR_5,NLPC_P60,Peptidase_C80,TcdA_TcdB,TcdA_TcdB_pore,TcdB_N BJHFPPGC_01722 1046629.Ssal_00756 4.24e-288 788.0 COG2966@1|root,COG3610@1|root,COG2966@2|Bacteria,COG3610@2|Bacteria,1TSE8@1239|Firmicutes 1239|Firmicutes K Psort location CytoplasmicMembrane, score - - - - - - - - - - - - Acetyltransf_7,ThrE,ThrE_2 BJHFPPGC_01723 1046629.Ssal_00757 1.38e-226 625.0 COG2376@1|root,COG2376@2|Bacteria,1TP92@1239|Firmicutes,4H9VS@91061|Bacilli 91061|Bacilli G Dihydroxyacetone kinase dhaK GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0047324 2.7.1.121 ko:K05878 ko00561,ko01100,map00561,map01100 - R01012 RC00015,RC00017 ko00000,ko00001,ko01000 - - - Dak1 BJHFPPGC_01724 1046629.Ssal_00758 2.84e-123 352.0 COG1461@1|root,COG1461@2|Bacteria,1V4FH@1239|Firmicutes,4HGZY@91061|Bacilli 91061|Bacilli S Dihydroxyacetone kinase dhaL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0046872,GO:0047324,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.7.1.121 ko:K05879 ko00561,ko01100,map00561,map01100 - R01012 RC00015,RC00017 ko00000,ko00001,ko01000 - - - Dak2 BJHFPPGC_01725 1046629.Ssal_00759 2e-77 231.0 COG3412@1|root,COG3412@2|Bacteria,1VF32@1239|Firmicutes 1239|Firmicutes S dihydroxyacetone kinase, phosphotransfer subunit dhaM GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0047324 2.7.1.121 ko:K05881 ko00561,map00561 - R01012 RC00015,RC00017 ko00000,ko00001,ko01000,ko02000 - - - EIIA-man BJHFPPGC_01726 1046629.Ssal_00760 9.43e-233 640.0 COG0673@1|root,COG0673@2|Bacteria,1TPT5@1239|Firmicutes,4HAPJ@91061|Bacilli 91061|Bacilli S oxidoreductase XK27_10475 - - - - - - - - - - - GFO_IDH_MocA BJHFPPGC_01727 1046629.Ssal_00761 1.13e-255 702.0 COG0371@1|root,COG0371@2|Bacteria,1TQFU@1239|Firmicutes,4HC8K@91061|Bacilli 91061|Bacilli C glycerol dehydrogenase gldA - 1.1.1.6 ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 - R01034,R10715,R10717 RC00029,RC00117,RC00670 ko00000,ko00001,ko01000 - - - Fe-ADH BJHFPPGC_01728 1511.CLOST_2006 2.14e-06 50.8 2BYV2@1|root,33ICM@2|Bacteria,1VMF3@1239|Firmicutes,256VA@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - BJHFPPGC_01729 904306.HMPREF9192_1056 0.0 977.0 COG4868@1|root,COG4868@2|Bacteria,1TQYE@1239|Firmicutes,4HDNX@91061|Bacilli 91061|Bacilli S Belongs to the UPF0371 family XK27_07020 - - - - - - - - - - - DUF1846 BJHFPPGC_01730 904306.HMPREF9192_1057 6.68e-268 737.0 COG0577@1|root,COG0577@2|Bacteria,1TT8B@1239|Firmicutes,4HFDY@91061|Bacilli 91061|Bacilli V Efflux ABC transporter, permease protein vex1 - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD BJHFPPGC_01731 1046629.Ssal_00766 3.04e-141 399.0 COG1136@1|root,COG1136@2|Bacteria,1TP5M@1239|Firmicutes,4HBJW@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein vex2 - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran BJHFPPGC_01732 904306.HMPREF9192_1059 9.21e-304 831.0 COG0577@1|root,COG0577@2|Bacteria,1TPSE@1239|Firmicutes,4HDMR@91061|Bacilli 91061|Bacilli V Efflux ABC transporter, permease protein vex3 - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX BJHFPPGC_01733 999425.HMPREF9186_00549 7.15e-148 417.0 COG0745@1|root,COG0745@2|Bacteria,1TT7R@1239|Firmicutes,4HG6F@91061|Bacilli 91061|Bacilli K Response regulator receiver domain protein vncR - - - - - - - - - - - Response_reg,Trans_reg_C BJHFPPGC_01734 1046629.Ssal_00769 3.89e-286 785.0 COG0642@1|root,COG0642@2|Bacteria,1TQZD@1239|Firmicutes,4HDFP@91061|Bacilli 91061|Bacilli T Histidine kinase vncS - 2.7.13.3 ko:K10819 - - - - ko00000,ko01000 - - - HAMP,HATPase_c,HATPase_c_5,HisKA BJHFPPGC_01735 904306.HMPREF9192_1062 0.0 1060.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli 91061|Bacilli G COG0366 Glycosidases dexB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.2.1.70 ko:K01215 - - - - ko00000,ko01000 - - - Alpha-amylase,DUF3459,Malt_amylase_C BJHFPPGC_01736 1046629.Ssal_00771 1.34e-234 645.0 COG1609@1|root,COG1609@2|Bacteria,1TPZJ@1239|Firmicutes,4HC9Z@91061|Bacilli 91061|Bacilli K Transcriptional regulator galR - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 BJHFPPGC_01737 435842.HMPREF0848_00971 2.83e-283 773.0 COG0153@1|root,COG0153@2|Bacteria,1TPD0@1239|Firmicutes,4HARP@91061|Bacilli 91061|Bacilli G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) galK GO:0005975,GO:0005996,GO:0006012,GO:0008150,GO:0008152,GO:0019318,GO:0044238,GO:0044281,GO:0071704 2.7.1.6 ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00554,M00632 R01092 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko04147 - - - GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg BJHFPPGC_01738 1046629.Ssal_00773 0.0 988.0 COG4468@1|root,COG4468@2|Bacteria,1TPBN@1239|Firmicutes,4HAYJ@91061|Bacilli 91061|Bacilli G UDPglucose--hexose-1-phosphate uridylyltransferase galT - 2.7.7.12 ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955 RC00002 ko00000,ko00001,ko00002,ko01000 - - - GalP_UDP_tr_C,GalP_UDP_transf BJHFPPGC_01739 435842.HMPREF0848_00969 2.45e-247 678.0 COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,4H9U5@91061|Bacilli 91061|Bacilli M Belongs to the NAD(P)-dependent epimerase dehydratase family galE - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd BJHFPPGC_01740 1046629.Ssal_00775 6.88e-257 703.0 COG2017@1|root,COG2017@2|Bacteria,1V5UK@1239|Firmicutes,4HTRY@91061|Bacilli 91061|Bacilli G Catalyzes the interconversion of alpha and beta anomers of maltose galM - 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 - - - Aldose_epim BJHFPPGC_01741 1046629.Ssal_00776 0.0 1219.0 COG2190@1|root,COG2211@1|root,COG2190@2|Bacteria,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,4HCDS@91061|Bacilli 91061|Bacilli G transporter lacS GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K11104,ko:K16209 - - - - ko00000,ko02000 2.A.2.1,2.A.2.2 - - MFS_2,PTS_EIIA_1 BJHFPPGC_01742 1046629.Ssal_00777 0.0 2076.0 COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,4HANW@91061|Bacilli 91061|Bacilli G -beta-galactosidase lacL - 3.2.1.23 ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 - R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 - - - Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N BJHFPPGC_01743 1046629.Ssal_00779 1.42e-267 734.0 COG0457@1|root,COG0457@2|Bacteria,1VBH7@1239|Firmicutes,4IS2V@91061|Bacilli 91061|Bacilli S Tetratricopeptide repeat - - - - - - - - - - - - - BJHFPPGC_01744 1046629.Ssal_00780 3.44e-200 554.0 COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4HARE@91061|Bacilli 91061|Bacilli C reductase yvgN - - - - - - - - - - - Aldo_ket_red BJHFPPGC_01745 1046629.Ssal_00781 2.97e-41 135.0 2DQ9B@1|root,335EQ@2|Bacteria,1VIWV@1239|Firmicutes,4HQTB@91061|Bacilli 91061|Bacilli - - XK27_10490 - - - - - - - - - - - - BJHFPPGC_01746 1046629.Ssal_00782 5.39e-52 164.0 COG2026@1|root,COG2026@2|Bacteria 2|Bacteria DJ nuclease activity - - - ko:K06218 - - - - ko00000,ko02048 - - - ParE_toxin BJHFPPGC_01747 904306.HMPREF9192_1065 2.75e-146 414.0 COG3619@1|root,COG3619@2|Bacteria,1V9ME@1239|Firmicutes 1239|Firmicutes S Protein of unknown function (DUF1275) - - - - - - - - - - - - DUF1275 BJHFPPGC_01748 1046629.Ssal_00784 3.4e-138 392.0 COG0778@1|root,COG0778@2|Bacteria,1UXYI@1239|Firmicutes,4HBMN@91061|Bacilli 91061|Bacilli C nitroreductase yodC - - - - - - - - - - - Nitroreductase BJHFPPGC_01749 1046629.Ssal_00785 5.89e-161 451.0 COG0745@1|root,COG0745@2|Bacteria,1TT2Z@1239|Firmicutes,4HDGH@91061|Bacilli 91061|Bacilli T Xre family transcriptional regulator - - - - - - - - - - - - Response_reg,Trans_reg_C BJHFPPGC_01750 1046629.Ssal_00786 1.34e-182 511.0 COG0642@1|root,COG2205@2|Bacteria,1UYK9@1239|Firmicutes,4IPWV@91061|Bacilli 91061|Bacilli T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HATPase_c_5,HisKA BJHFPPGC_01751 1046629.Ssal_00787 4.92e-120 342.0 2DDQQ@1|root,2ZIXD@2|Bacteria,1V3FF@1239|Firmicutes 1239|Firmicutes S Psort location Cytoplasmic, score - - - - - - - - - - - - - BJHFPPGC_01752 645512.GCWU000246_01712 7.86e-64 213.0 2DB9A@1|root,2Z7VI@2|Bacteria,3TB03@508458|Synergistetes 508458|Synergistetes L Adenine-specific methyltransferase EcoRI - - - - - - - - - - - - EcoRI_methylase BJHFPPGC_01759 1046629.Ssal_01817 5.06e-208 577.0 COG1227@1|root,COG1227@2|Bacteria,1TPH6@1239|Firmicutes,4H9T8@91061|Bacilli 91061|Bacilli C inorganic pyrophosphatase ppaC GO:0003674,GO:0003824,GO:0004427,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237,GO:0044424,GO:0044464 3.6.1.1 ko:K15986 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - DHH,DHHA2 BJHFPPGC_01760 1046629.Ssal_01816 2.28e-134 382.0 2F8BM@1|root,340QP@2|Bacteria,1W4V4@1239|Firmicutes,4HR72@91061|Bacilli 91061|Bacilli S Domain of unknown function (DUF1803) - - - - - - - - - - - - DUF1803 BJHFPPGC_01761 1046629.Ssal_01815 1.99e-132 374.0 COG3557@1|root,COG3557@2|Bacteria,1TRX8@1239|Firmicutes,4H9NM@91061|Bacilli 91061|Bacilli J Belongs to the UPF0374 family ygaC - - ko:K07586 - - - - ko00000 - - - DUF402 BJHFPPGC_01762 1046629.Ssal_01814 1.27e-175 490.0 COG2137@1|root,COG2137@2|Bacteria,1V72V@1239|Firmicutes,4HKE3@91061|Bacilli 91061|Bacilli S Regulatory protein RecX recX - - ko:K03565 - - - - ko00000,ko03400 - - - RecX BJHFPPGC_01763 1046629.Ssal_01813 9.25e-315 858.0 COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli 91061|Bacilli J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family rumA_1 - 2.1.1.190,2.1.1.35 ko:K00557,ko:K03215 - - - - ko00000,ko01000,ko03009,ko03016 - - - TRAM,tRNA_U5-meth_tr BJHFPPGC_01764 1046629.Ssal_01812 5.34e-245 672.0 COG2502@1|root,COG2502@2|Bacteria,1TP28@1239|Firmicutes,4HAEC@91061|Bacilli 91061|Bacilli E aspartate--ammonia ligase asnA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.1.1 ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 - R00483 RC00010 ko00000,ko00001,ko01000 - - - AsnA BJHFPPGC_01765 1046629.Ssal_01811 0.0 890.0 COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,4HAEP@91061|Bacilli 91061|Bacilli E Belongs to the aspartokinase family lysC GO:0000166,GO:0003674,GO:0003824,GO:0004072,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017076,GO:0019202,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU03790 AA_kinase,ACT,ACT_7 BJHFPPGC_01766 1046629.Ssal_01810 4.34e-151 424.0 COG0637@1|root,COG0637@2|Bacteria,1VA1U@1239|Firmicutes,4HMKX@91061|Bacilli 91061|Bacilli S HAD hydrolase, family IA, variant 3 yhfA - - - - - - - - - - - HAD_2 BJHFPPGC_01767 1046629.Ssal_01809 3.92e-180 502.0 COG1024@1|root,COG1024@2|Bacteria,1TQ2V@1239|Firmicutes,4HBT0@91061|Bacilli 91061|Bacilli I Belongs to the enoyl-CoA hydratase isomerase family phaB GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006635,GO:0006636,GO:0008150,GO:0008152,GO:0008610,GO:0009056,GO:0009058,GO:0009062,GO:0009987,GO:0016042,GO:0016053,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016860,GO:0016863,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0033559,GO:0034017,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:0072330,GO:1901575,GO:1901576 5.3.3.14,5.3.3.18 ko:K15866,ko:K18474 ko00061,ko00360,ko01120,map00061,map00360,map01120 - R07639,R09837,R09839 RC00004,RC00326,RC01078,RC02689,RC03003 ko00000,ko00001,ko01000,ko01004 - - - ECH_1 BJHFPPGC_01768 1046629.Ssal_01808 2.67e-96 280.0 COG1846@1|root,COG1846@2|Bacteria,1V6GY@1239|Firmicutes,4HIMR@91061|Bacilli 91061|Bacilli K Transcriptional regulator, MarR family XK27_02735 - - - - - - - - - - - MarR BJHFPPGC_01769 1046629.Ssal_01807 9.99e-220 607.0 COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,4HATK@91061|Bacilli 91061|Bacilli I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C BJHFPPGC_01770 1046629.Ssal_01806 2.12e-40 134.0 COG0236@1|root,COG0236@2|Bacteria,1VGIY@1239|Firmicutes,4HP0V@91061|Bacilli 91061|Bacilli IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding BJHFPPGC_01771 1046629.Ssal_01805 3.23e-221 611.0 COG2070@1|root,COG2070@2|Bacteria,1TPC3@1239|Firmicutes,4H9T0@91061|Bacilli 91061|Bacilli S 2-Nitropropane dioxygenase fabK - 1.3.1.9 ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00083 R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000,ko01004 - - - NMO BJHFPPGC_01772 1046629.Ssal_01804 1.51e-207 575.0 COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,4HBCU@91061|Bacilli 91061|Bacilli I Malonyl CoA-acyl carrier protein transacylase fabD - 2.3.1.39 ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 - - - Acyl_transf_1 BJHFPPGC_01773 904306.HMPREF9192_0291 2.76e-163 458.0 COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4HAA6@91061|Bacilli 91061|Bacilli IQ reductase fabG GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - iYO844.BSU15910 adh_short_C2 BJHFPPGC_01774 1046629.Ssal_01802 1.06e-296 809.0 COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli 91061|Bacilli I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabF - 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt BJHFPPGC_01775 1046629.Ssal_01801 1.85e-83 249.0 COG0511@1|root,COG0511@2|Bacteria,1VAB7@1239|Firmicutes,4HKCS@91061|Bacilli 91061|Bacilli I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA accB - - ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742 RC00040,RC00367 ko00000,ko00001,ko00002 - - - Biotin_lipoyl BJHFPPGC_01776 1046629.Ssal_01800 1.19e-93 273.0 COG0764@1|root,COG0764@2|Bacteria,1V6EX@1239|Firmicutes,4HGX1@91061|Bacilli 91061|Bacilli I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs fabZ - 4.2.1.59 ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA BJHFPPGC_01777 1046629.Ssal_01798 0.0 890.0 COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,4HARK@91061|Bacilli 91061|Bacilli I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism accC - 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 BJHFPPGC_01778 1046629.Ssal_01797 1.71e-204 566.0 COG0777@1|root,COG0777@2|Bacteria,1TP4U@1239|Firmicutes,4HAI7@91061|Bacilli 91061|Bacilli I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA accD - 2.1.3.15,6.4.1.2 ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans BJHFPPGC_01779 1046629.Ssal_01796 4.63e-177 494.0 COG0825@1|root,COG0825@2|Bacteria,1UHNS@1239|Firmicutes,4HA4C@91061|Bacilli 91061|Bacilli I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA accA - 2.1.3.15,6.4.1.2 ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - ACCA BJHFPPGC_01780 1046629.Ssal_01795 6.58e-116 331.0 COG1854@1|root,COG1854@2|Bacteria,1V1V3@1239|Firmicutes,4HFR0@91061|Bacilli 91061|Bacilli H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) luxS - 4.4.1.21 ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 M00609 R01291 RC00069,RC01929 ko00000,ko00001,ko00002,ko01000 - - - LuxS BJHFPPGC_01781 904306.HMPREF9192_0315 2.22e-290 804.0 COG1418@1|root,COG4372@1|root,COG1418@2|Bacteria,COG4372@2|Bacteria,1TP48@1239|Firmicutes,4HC9J@91061|Bacilli 91061|Bacilli D Endoribonuclease that initiates mRNA decay rny GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K18682 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DUF3552,HD,KH_1 BJHFPPGC_01782 1046629.Ssal_01793 3.92e-165 463.0 COG1349@1|root,COG1349@2|Bacteria,1TSF8@1239|Firmicutes,4HDT9@91061|Bacilli 91061|Bacilli K transcriptional fruR - - ko:K03436 - - - - ko00000,ko03000 - - - DeoRC,HTH_DeoR BJHFPPGC_01783 1046629.Ssal_01792 4.55e-212 586.0 COG1105@1|root,COG1105@2|Bacteria,1TQ36@1239|Firmicutes,4HANU@91061|Bacilli 91061|Bacilli H Belongs to the carbohydrate kinase PfkB family. LacC subfamily pfkB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0071704 2.7.1.56 ko:K00882 ko00051,map00051 - R02071 RC00002,RC00017 ko00000,ko00001,ko01000 - - iYO844.BSU14390 PfkB BJHFPPGC_01784 1046629.Ssal_01791 0.0 1197.0 COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,4H9KR@91061|Bacilli 91061|Bacilli G phosphotransferase system fruA - 2.7.1.202 ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_EIIA_2,PTS_EIIC,PTS_IIB BJHFPPGC_01785 435842.HMPREF0848_00027 0.0 887.0 COG1249@1|root,COG1249@2|Bacteria,1TQFH@1239|Firmicutes,4HCT8@91061|Bacilli 91061|Bacilli C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family gor GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim BJHFPPGC_01786 1046629.Ssal_01788 4.99e-289 790.0 COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,4HBJM@91061|Bacilli 91061|Bacilli H Belongs to the folylpolyglutamate synthase family folC - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS08370 Mur_ligase_C,Mur_ligase_M BJHFPPGC_01787 1005705.HMPREF9967_0802 5.14e-08 56.6 2DIXV@1|root,304C8@2|Bacteria,1TWH5@1239|Firmicutes,4I5AH@91061|Bacilli,43G9W@68892|Streptococcus infantis 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_01788 1046629.Ssal_01786 6.74e-267 731.0 COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,4HAEE@91061|Bacilli 91061|Bacilli E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes iscS2 - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 BJHFPPGC_01789 904306.HMPREF9192_0323 1.85e-284 778.0 COG0301@1|root,COG0301@2|Bacteria,1TPNW@1239|Firmicutes,4HAV9@91061|Bacilli 91061|Bacilli H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS thiI - 2.8.1.4 ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07461 - ko00000,ko00001,ko01000,ko03016 - - - THUMP,ThiI BJHFPPGC_01790 1046629.Ssal_01782 0.0 992.0 COG0438@1|root,COG0438@2|Bacteria,1TR6K@1239|Firmicutes,4HGDG@91061|Bacilli 91061|Bacilli M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon gtf1 - - - - - - - - - - - Glycos_transf_1 BJHFPPGC_01791 904306.HMPREF9192_0325 0.0 879.0 COG0438@1|root,COG0438@2|Bacteria,1TQZR@1239|Firmicutes 1239|Firmicutes M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1 gtf2 - - - - - - - - - - - - BJHFPPGC_01792 1046629.Ssal_01780 3.1e-107 311.0 COG0454@1|root,COG0456@2|Bacteria 2|Bacteria K acetyltransferase - - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1,Acetyltransf_7 BJHFPPGC_01793 264199.stu0417 1.99e-64 198.0 COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,4HIGK@91061|Bacilli 91061|Bacilli J This protein binds to 23S rRNA in the presence of protein L20 rplU GO:0003674,GO:0003735,GO:0005198 - ko:K02888 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L21p BJHFPPGC_01794 1046629.Ssal_01778 1.55e-61 189.0 COG0211@1|root,COG0211@2|Bacteria,1V6HW@1239|Firmicutes,4HIMN@91061|Bacilli 91061|Bacilli J Belongs to the bacterial ribosomal protein bL27 family rpmA GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02899 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27 BJHFPPGC_01795 322159.STER_0457 5.69e-170 474.0 COG1670@1|root,COG1670@2|Bacteria 2|Bacteria J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins ydaF_2 - - - - - - - - - - - Acetyltransf_3 BJHFPPGC_01796 1046629.Ssal_01776 2.63e-82 243.0 COG4835@1|root,COG4835@2|Bacteria,1VHA6@1239|Firmicutes,4HPTC@91061|Bacilli 91061|Bacilli S cog cog4835 WQ51_03320 - - - - - - - - - - - DUF1149 BJHFPPGC_01797 1046629.Ssal_01775 7.65e-188 523.0 COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,4HVKJ@91061|Bacilli 91061|Bacilli S EDD domain protein, DegV family - - - - - - - - - - - - DegV BJHFPPGC_01798 1046629.Ssal_01774 2.58e-178 497.0 COG0289@1|root,COG0289@2|Bacteria,1TR9D@1239|Firmicutes,4HA5X@91061|Bacilli 91061|Bacilli E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate dapB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU22490 DapB_C,DapB_N BJHFPPGC_01799 904306.HMPREF9192_0334 4.68e-279 764.0 COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,4HB2W@91061|Bacilli 91061|Bacilli J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate cca - 2.7.7.72 ko:K00974 ko03013,map03013 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016 - - - PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2 BJHFPPGC_01800 1046629.Ssal_01772 0.0 1181.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4H9TK@91061|Bacilli 91061|Bacilli S abc transporter atp-binding protein yfmR - - ko:K15738 - - - - ko00000,ko02000 3.A.1.120.6 - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn BJHFPPGC_01801 764298.STRMA_0561 6.23e-30 114.0 COG3247@1|root,COG3247@2|Bacteria,1VK2X@1239|Firmicutes 1239|Firmicutes S Short repeat of unknown function (DUF308) - - - - - - - - - - - - DUF308 BJHFPPGC_01802 904306.HMPREF9192_0338 4.93e-166 466.0 COG1051@1|root,COG1051@2|Bacteria,1TST7@1239|Firmicutes,4HEFP@91061|Bacilli 91061|Bacilli F AdP-ribose pyrophosphatase - - - - - - - - - - - - NUDIX BJHFPPGC_01803 1046629.Ssal_01769 7.31e-269 735.0 COG1057@1|root,COG3172@1|root,COG1057@2|Bacteria,COG3172@2|Bacteria,1TQ29@1239|Firmicutes,4HBZT@91061|Bacilli 91061|Bacilli H adenylyltransferase nadR - - - - - - - - - - - AAA_28,CTP_transf_like BJHFPPGC_01804 1046629.Ssal_01768 0.0 878.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,4HAEI@91061|Bacilli 91061|Bacilli E Belongs to the Glu Leu Phe Val dehydrogenases family gdhA - 1.4.1.4 ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 - R00248 RC00006,RC02799 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,ELFV_dehydrog_N BJHFPPGC_01805 1046629.Ssal_01767 0.0 974.0 COG5617@1|root,COG5617@2|Bacteria,1VS0Z@1239|Firmicutes,4HJQE@91061|Bacilli 91061|Bacilli S Psort location CytoplasmicMembrane, score - - - - - - - - - - - - - BJHFPPGC_01806 1046629.Ssal_01766 7.84e-92 268.0 COG0242@1|root,COG0242@2|Bacteria,1V73T@1239|Firmicutes,4HGYC@91061|Bacilli 91061|Bacilli J Removes the formyl group from the N-terminal Met of newly synthesized proteins def_1 - 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase BJHFPPGC_01807 435842.HMPREF0848_00049 1.36e-95 279.0 COG1846@1|root,COG1846@2|Bacteria 2|Bacteria K DNA-binding transcription factor activity - - - - - - - - - - - - HTH_27,MarR,MarR_2 BJHFPPGC_01808 1046629.Ssal_01764 0.0 1093.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H9SC@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein lmrA1 - - ko:K02021,ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21 - - ABC_membrane,ABC_tran BJHFPPGC_01809 1046629.Ssal_01763 0.0 1111.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein lmrA2 - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran BJHFPPGC_01810 1046629.Ssal_01762 8.72e-142 400.0 COG0454@1|root,COG0456@2|Bacteria,1VF01@1239|Firmicutes,4HPKN@91061|Bacilli 91061|Bacilli K Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_7 BJHFPPGC_01811 1046629.Ssal_01761 7.21e-143 403.0 COG2357@1|root,COG2357@2|Bacteria,1TQ2F@1239|Firmicutes,4HTR5@91061|Bacilli 91061|Bacilli S Region found in RelA / SpoT proteins - - 2.7.6.5 ko:K00951 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - - RelA_SpoT BJHFPPGC_01812 1046629.Ssal_01760 6.81e-150 422.0 COG0745@1|root,COG0745@2|Bacteria,1TPU2@1239|Firmicutes,4HG2E@91061|Bacilli 91061|Bacilli T response regulator dltr - - - - - - - - - - - Response_reg,Trans_reg_C BJHFPPGC_01813 1046629.Ssal_01758 2.26e-269 740.0 COG0642@1|root,COG0642@2|Bacteria,1UHQH@1239|Firmicutes,4HAHG@91061|Bacilli 91061|Bacilli T Histidine kinase sptS - - - - - - - - - - - HATPase_c,HisKA BJHFPPGC_01814 1046629.Ssal_01757 2.78e-168 471.0 COG0528@1|root,COG0528@2|Bacteria,1TPXN@1239|Firmicutes,4H9UB@91061|Bacilli 91061|Bacilli F Catalyzes the reversible phosphorylation of UMP to UDP pyrH - 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - iSB619.SA_RS06240 AA_kinase BJHFPPGC_01815 1046629.Ssal_01756 1.94e-118 340.0 COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,4HFSH@91061|Bacilli 91061|Bacilli J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another frr GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K02838 - - - - ko00000,ko03012 - - - RRF BJHFPPGC_01816 1046629.Ssal_01755 4.92e-207 572.0 COG2996@1|root,COG2996@2|Bacteria,1TQ1Z@1239|Firmicutes,4HDAZ@91061|Bacilli 91061|Bacilli S Protein conserved in bacteria yitL - - ko:K00243 - - - - ko00000 - - - S1_2 BJHFPPGC_01817 904306.HMPREF9192_0353 2.72e-46 148.0 COG4479@1|root,COG4479@2|Bacteria,1VFI4@1239|Firmicutes,4HR7P@91061|Bacilli 91061|Bacilli S Belongs to the UPF0346 family yozE - - - - - - - - - - - YozE_SAM_like BJHFPPGC_01818 1046629.Ssal_01753 1.64e-203 574.0 COG1388@1|root,COG1388@2|Bacteria,1V61Q@1239|Firmicutes,4HHT0@91061|Bacilli 91061|Bacilli M LysM domain protein sip - - - - - - - - - - - LysM BJHFPPGC_01819 322159.STER_0480 2.42e-239 659.0 COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,4HBD5@91061|Bacilli 91061|Bacilli T phosphate starvation-inducible protein PhoH phoH - - ko:K06217 - - - - ko00000 - - - PhoH BJHFPPGC_01823 904306.HMPREF9192_0360 0.0 1332.0 COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,4H9VC@91061|Bacilli 91061|Bacilli J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g,tRNA_bind BJHFPPGC_01824 1046629.Ssal_01744 1.64e-203 563.0 COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4H9XJ@91061|Bacilli 91061|Bacilli S reductase - - 1.1.1.346 ko:K06221 - - R08878 RC00089 ko00000,ko01000 - - - Aldo_ket_red BJHFPPGC_01825 1046629.Ssal_01743 3.03e-215 594.0 COG0583@1|root,COG0583@2|Bacteria,1V53I@1239|Firmicutes,4HIEU@91061|Bacilli 91061|Bacilli K transcriptional regulator (lysR family) - - - - - - - - - - - - HTH_1,LysR_substrate BJHFPPGC_01826 435842.HMPREF0848_00071 1.36e-132 380.0 COG1266@1|root,COG1266@2|Bacteria,1VCV8@1239|Firmicutes 1239|Firmicutes S CAAX amino terminal protease family protein - - - ko:K07052 - - - - ko00000 - - - Abi BJHFPPGC_01827 1046629.Ssal_01741 0.0 1072.0 2DGEP@1|root,2ZVNT@2|Bacteria 2|Bacteria S Glucan-binding protein C - - - - - - - - - - - - GbpC,Gram_pos_anchor BJHFPPGC_01828 1046629.Ssal_01737 4.7e-213 590.0 COG4469@1|root,COG4469@2|Bacteria,1TRGD@1239|Firmicutes,4HFP5@91061|Bacilli 91061|Bacilli S Competence protein coiA - - ko:K06198 - - - - ko00000 - - - CoiA BJHFPPGC_01829 1046629.Ssal_01736 0.0 1196.0 COG1164@1|root,COG1164@2|Bacteria,1TP4P@1239|Firmicutes,4HA7X@91061|Bacilli 91061|Bacilli E oligoendopeptidase F pepF GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - ko:K08602 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3,Peptidase_M3_N BJHFPPGC_01830 904306.HMPREF9192_0364 6.07e-277 759.0 COG2223@1|root,COG2223@2|Bacteria,1TPR9@1239|Firmicutes,4HB93@91061|Bacilli 91061|Bacilli P COG0477 Permeases of the major facilitator superfamily oxlT - - ko:K08177 - - - - ko00000,ko02000 2.A.1.11 - - MFS_1 BJHFPPGC_01831 1046629.Ssal_01734 5.91e-155 436.0 COG4122@1|root,COG4122@2|Bacteria,1UF4M@1239|Firmicutes,4HE9E@91061|Bacilli 91061|Bacilli S O-Methyltransferase yrrM - 2.1.1.104 ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 M00039,M00350 R01942,R06578 RC00003,RC00392 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_3 BJHFPPGC_01832 1046629.Ssal_01733 2.64e-236 654.0 COG0760@1|root,COG0760@2|Bacteria 2|Bacteria O peptidyl-prolyl cis-trans isomerase activity prsA - 3.1.3.16,5.2.1.8 ko:K01802,ko:K03769,ko:K07533,ko:K20074 - - - - ko00000,ko01000,ko01009,ko03110 - - - Rotamase,Rotamase_2,SurA_N_3 BJHFPPGC_01833 435842.HMPREF0848_00077 7.66e-111 318.0 COG4894@1|root,COG4894@2|Bacteria,1VBT3@1239|Firmicutes,4HH8W@91061|Bacilli 91061|Bacilli S LURP-one-related XK27_03390 - - - - - - - - - - - LOR BJHFPPGC_01834 1046629.Ssal_01730 0.0 1707.0 COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,4H9XC@91061|Bacilli 91061|Bacilli J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD BJHFPPGC_01835 1046629.Ssal_01709 0.0 1477.0 COG0860@1|root,COG1705@1|root,COG0860@2|Bacteria,COG1705@2|Bacteria,1W25V@1239|Firmicutes,4HGXW@91061|Bacilli 91061|Bacilli M GBS Bsp-like repeat - - - - - - - - - - - - GBS_Bsp-like,Peptidase_C70,SH3_5,YSIRK_signal BJHFPPGC_01836 1046629.Ssal_01708 1.09e-172 482.0 COG3279@1|root,COG3279@2|Bacteria,1V392@1239|Firmicutes 1239|Firmicutes KT response regulator - - - ko:K07707 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg BJHFPPGC_01838 1046629.Ssal_01653 0.0 1179.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli 91061|Bacilli G pts system - - - ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 M00271 - - ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC BJHFPPGC_01840 904306.HMPREF9192_0421 0.0 872.0 COG1113@1|root,COG1113@2|Bacteria,1TP97@1239|Firmicutes,4H9QX@91061|Bacilli 91061|Bacilli E permease cycA - - ko:K03293,ko:K11737 - - - - ko00000,ko02000 2.A.3.1,2.A.3.1.7 - - AA_permease BJHFPPGC_01841 999425.HMPREF9186_01697 2.87e-52 164.0 COG4224@1|root,COG4224@2|Bacteria,1VEKJ@1239|Firmicutes,4HNIB@91061|Bacilli 91061|Bacilli S UPF0291 protein ynzC - - - - - - - - - - - DUF896 BJHFPPGC_01842 888048.HMPREF8577_2005 0.0 1268.0 COG0751@1|root,COG0751@2|Bacteria,1TNZ7@1239|Firmicutes,4H9NT@91061|Bacilli 91061|Bacilli J Glycyl-tRNA synthetase beta subunit glyS - 6.1.1.14 ko:K01879 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_1,tRNA_synt_2f BJHFPPGC_01843 1046629.Ssal_01658 1.23e-226 623.0 COG0752@1|root,COG0752@2|Bacteria,1TPW8@1239|Firmicutes,4HBCF@91061|Bacilli 91061|Bacilli J glycyl-tRNA synthetase alpha subunit glyQ - 6.1.1.14 ko:K01878 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2e BJHFPPGC_01844 889204.HMPREF9423_0703 5.54e-88 258.0 COG3791@1|root,COG3791@2|Bacteria 2|Bacteria S Glutathione-dependent formaldehyde-activating - - - - - - - - - - - - GFA BJHFPPGC_01845 1046629.Ssal_01659 7.52e-283 775.0 COG3949@1|root,COG3949@2|Bacteria,1U601@1239|Firmicutes,4HBYW@91061|Bacilli 91061|Bacilli S membrane - - - - - - - - - - - - - BJHFPPGC_01846 1046629.Ssal_01660 1.18e-278 761.0 COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,4HC6C@91061|Bacilli 91061|Bacilli G Belongs to the metallo-dependent hydrolases superfamily. NagA family nagA - 3.5.1.25 ko:K01443 ko00520,ko01130,map00520,map01130 - R02059 RC00166,RC00300 ko00000,ko00001,ko01000 - - - Amidohydro_1 BJHFPPGC_01847 1046629.Ssal_01661 0.0 1027.0 COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,4HAZ0@91061|Bacilli 91061|Bacilli P COG1283 Na phosphate symporter yjbB - - ko:K03324 - - - - ko00000,ko02000 2.A.58.2 - - Na_Pi_cotrans,PhoU BJHFPPGC_01848 1046629.Ssal_01662 8.01e-153 441.0 COG1705@1|root,COG1705@2|Bacteria 2|Bacteria NU amidase activity - - 3.4.17.14,3.5.1.28 ko:K01448,ko:K02395,ko:K07260 ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020 M00651,M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036 - - - Amidase_3,CHAP,CW_binding_1,GBS_Bsp-like,Glucosaminidase,SH3_5 BJHFPPGC_01849 1046629.Ssal_01663 2.25e-102 298.0 2E80M@1|root,332EU@2|Bacteria,1VJ8N@1239|Firmicutes,4HZSS@91061|Bacilli 91061|Bacilli S Bacterial inner membrane protein - - - - - - - - - - - - Imp-YgjV BJHFPPGC_01850 904306.HMPREF9192_0413 3.22e-181 506.0 COG0561@1|root,COG0561@2|Bacteria,1V1KS@1239|Firmicutes,4IPK6@91061|Bacilli 91061|Bacilli S Sucrose-6F-phosphate phosphohydrolase - - - - - - - - - - - - Hydrolase_3,S6PP BJHFPPGC_01851 1046629.Ssal_01666 3.1e-138 392.0 COG1705@1|root,COG1705@2|Bacteria 2|Bacteria NU amidase activity mur1 - 3.4.17.14,3.5.1.28 ko:K01448,ko:K02395,ko:K07260 ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020 M00651,M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036 - - - GBS_Bsp-like,Glucosaminidase,Rod-binding BJHFPPGC_01852 1046629.Ssal_01667 1.08e-69 211.0 COG0347@1|root,COG0347@2|Bacteria,1V9Z5@1239|Firmicutes,4HJ6Z@91061|Bacilli 91061|Bacilli K Belongs to the P(II) protein family glnB - - ko:K04751 ko02020,map02020 - - - ko00000,ko00001 - - - P-II BJHFPPGC_01853 365659.smi_0683 1.94e-288 788.0 COG0004@1|root,COG0004@2|Bacteria,1TQYG@1239|Firmicutes,4HBGK@91061|Bacilli 91061|Bacilli P Ammonium Transporter amt - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp BJHFPPGC_01854 1046629.Ssal_01669 9.87e-204 564.0 COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,4HAH8@91061|Bacilli 91061|Bacilli H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase BJHFPPGC_01855 1046629.Ssal_01670 2e-73 219.0 COG4467@1|root,COG4467@2|Bacteria,1VA1F@1239|Firmicutes,4HKND@91061|Bacilli 91061|Bacilli L Involved in initiation control of chromosome replication yabA GO:0003674,GO:0005488,GO:0005515,GO:0042802 - - - - - - - - - - YabB BJHFPPGC_01856 1046629.Ssal_01671 4.74e-176 492.0 COG1774@1|root,COG1774@2|Bacteria,1TP1V@1239|Firmicutes,4H9M9@91061|Bacilli 91061|Bacilli S stage 0 sporulation protein yaaT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - - - - - - - - - - PSP1 BJHFPPGC_01857 904306.HMPREF9192_0406 1.45e-202 561.0 COG0470@1|root,COG0470@2|Bacteria,1TRVS@1239|Firmicutes,4HA3T@91061|Bacilli 91061|Bacilli L dna polymerase iii holB - 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNApol3-delta_C BJHFPPGC_01858 904306.HMPREF9192_0405 1.56e-138 392.0 COG0125@1|root,COG0125@2|Bacteria,1V1HE@1239|Firmicutes,4HGWR@91061|Bacilli 91061|Bacilli F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS02535 Thymidylate_kin BJHFPPGC_01860 435842.HMPREF0848_00124 0.0 1279.0 COG0021@1|root,COG0021@2|Bacteria,1TPIB@1239|Firmicutes,4HADA@91061|Bacilli 91061|Bacilli G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate tkt - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C,Transketolase_N BJHFPPGC_01861 1046629.Ssal_01675 7.68e-174 485.0 COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,4HAPT@91061|Bacilli 91061|Bacilli G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - TIM BJHFPPGC_01862 1046629.Ssal_01677 3.2e-285 779.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,4HAEH@91061|Bacilli 91061|Bacilli J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis tuf GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009274,GO:0009275,GO:0009986,GO:0010339,GO:0016020,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0035821,GO:0044003,GO:0044068,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484 - ko:K02358,ko:K15771 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 3.A.1.1.16,3.A.1.1.2 - - GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 BJHFPPGC_01863 435842.HMPREF0848_00121 1.37e-275 757.0 COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,4HAEV@91061|Bacilli 91061|Bacilli D Belongs to the SEDS family ftsW - - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE BJHFPPGC_01864 1046629.Ssal_01679 1.24e-89 263.0 COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,4HKHS@91061|Bacilli 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane atpC GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_DE,ATP-synt_DE_N BJHFPPGC_01865 1046629.Ssal_01680 0.0 907.0 COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,4HAT6@91061|Bacilli 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - iSB619.SA_RS10965 ATP-synt_ab,ATP-synt_ab_N BJHFPPGC_01866 435842.HMPREF0848_00118 9.08e-202 559.0 COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,4HB0E@91061|Bacilli 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex atpG - - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - iSB619.SA_RS10970,iYO844.BSU36820 ATP-synt BJHFPPGC_01867 904306.HMPREF9192_0397 0.0 964.0 COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,4HAMZ@91061|Bacilli 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - iSB619.SA_RS10975 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N BJHFPPGC_01868 1046629.Ssal_01683 8.62e-114 327.0 COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,4HKW1@91061|Bacilli 91061|Bacilli C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpH - - ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - OSCP BJHFPPGC_01869 1046629.Ssal_01684 1.46e-101 295.0 COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,4HM64@91061|Bacilli 91061|Bacilli C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) atpF - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - iYO844.BSU36850 ATP-synt_B BJHFPPGC_01870 1046629.Ssal_01685 4.97e-157 441.0 COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,4H9NV@91061|Bacilli 91061|Bacilli C it plays a direct role in the translocation of protons across the membrane atpB GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A BJHFPPGC_01871 1123298.KB904069_gene1213 1.44e-23 90.9 COG0636@1|root,2ZI0B@2|Bacteria 2|Bacteria C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C BJHFPPGC_01872 888746.HMPREF9180_1411 1.42e-72 233.0 2DBF2@1|root,2Z8W0@2|Bacteria,1V0KF@1239|Firmicutes,4HCQM@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_01873 904306.HMPREF9192_0781 5.74e-18 76.3 COG2963@1|root,COG2963@2|Bacteria,1VFYX@1239|Firmicutes,4HNKT@91061|Bacilli 91061|Bacilli L transposase activity - - - - - - - - - - - - HTH_28 BJHFPPGC_01874 861455.HMPREF9184_00157 0.0 1412.0 COG0553@1|root,COG1502@1|root,COG0553@2|Bacteria,COG1502@2|Bacteria 2|Bacteria I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol - - - - - - - - - - - - Helicase_C,PLDc_2,ResIII,SNF2_N BJHFPPGC_01875 861455.HMPREF9184_00156 3.01e-220 617.0 COG1475@1|root,COG1475@2|Bacteria,1U5BV@1239|Firmicutes,4HC81@91061|Bacilli 91061|Bacilli K DNA binding - - - - - - - - - - - - ParBc BJHFPPGC_01876 861455.HMPREF9184_00155 0.0 937.0 COG0270@1|root,COG0270@2|Bacteria,1TSNX@1239|Firmicutes,4HFAI@91061|Bacilli 91061|Bacilli L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family dcm GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006304,GO:0006305,GO:0006306,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0008150,GO:0008152,GO:0008168,GO:0009307,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0032776,GO:0034641,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044355,GO:0044728,GO:0046483,GO:0050896,GO:0071704,GO:0090304,GO:0099046,GO:1901360 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase,N6_N4_Mtase BJHFPPGC_01879 1046629.Ssal_00550 0.0 1759.0 COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,4HB85@91061|Bacilli 91061|Bacilli J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 BJHFPPGC_01880 1280685.AUKC01000042_gene2151 8.15e-29 113.0 COG1403@1|root,COG1403@2|Bacteria,1US9X@1239|Firmicutes,25A94@186801|Clostridia,4BZ3D@830|Butyrivibrio 186801|Clostridia V HNH nucleases - - - - - - - - - - - - HNH BJHFPPGC_01883 1123314.AUIO01000005_gene141 1.38e-17 82.0 COG4469@1|root,COG4469@2|Bacteria,1TRGD@1239|Firmicutes,4HFP5@91061|Bacilli 91061|Bacilli S Competence protein coiA - - ko:K06198 - - - - ko00000 - - - CoiA BJHFPPGC_01885 322159.STER_0508 9.55e-189 526.0 COG2962@1|root,COG2962@2|Bacteria,1TQF2@1239|Firmicutes,4HAYU@91061|Bacilli 91061|Bacilli S Transporter rarD - - ko:K05786 - - - - ko00000,ko02000 2.A.7.7 - - EamA BJHFPPGC_01886 1046629.Ssal_01693 1.24e-196 546.0 COG0083@1|root,COG0083@2|Bacteria,1TRWS@1239|Firmicutes,4HCQN@91061|Bacilli 91061|Bacilli E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate thrB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06620 GHMP_kinases_C,GHMP_kinases_N BJHFPPGC_01887 1046629.Ssal_01694 1.41e-301 823.0 COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,4HBAP@91061|Bacilli 91061|Bacilli E homoserine dehydrogenase hom - 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06610 ACT,Homoserine_dh,NAD_binding_3 BJHFPPGC_01888 1046629.Ssal_01695 7.02e-190 529.0 COG0726@1|root,COG0726@2|Bacteria,1V6AW@1239|Firmicutes,4HHC9@91061|Bacilli 91061|Bacilli G deacetylase icaB - - - - - - - - - - - Polysacc_deac_1 BJHFPPGC_01889 1046629.Ssal_01696 3.68e-257 706.0 COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,4H9VZ@91061|Bacilli 91061|Bacilli E acetylornithine aminotransferase argD GO:0003674,GO:0003824,GO:0003992,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 BJHFPPGC_01890 1046629.Ssal_01697 3.2e-158 445.0 COG0548@1|root,COG0548@2|Bacteria,1TP0N@1239|Firmicutes 1239|Firmicutes E Belongs to the acetylglutamate kinase family. ArgB subfamily argB GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R02649 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase BJHFPPGC_01891 435842.HMPREF0848_00097 1.83e-279 764.0 COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,4H9TQ@91061|Bacilli 91061|Bacilli E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate argJ GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259,R02282 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - ArgJ BJHFPPGC_01892 1046629.Ssal_01699 1.56e-233 644.0 COG0002@1|root,COG0002@2|Bacteria,1TPVI@1239|Firmicutes,4H9YD@91061|Bacilli 91061|Bacilli E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde argC GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU11190 Semialdhyde_dh,Semialdhyde_dhC BJHFPPGC_01893 1046629.Ssal_01700 4.89e-282 771.0 COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,4HAHQ@91061|Bacilli 91061|Bacilli E mutations do not affect methionine salvage in vivo however mtnE - - ko:K08969 ko00270,ko01100,map00270,map01100 M00034 R07396 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 BJHFPPGC_01894 904306.HMPREF9192_0374 7.66e-178 496.0 COG0388@1|root,COG0388@2|Bacteria,1TQDK@1239|Firmicutes,4HC44@91061|Bacilli 91061|Bacilli S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase mtnU - 3.5.1.3 ko:K13566 ko00250,map00250 - R00269,R00348 RC00010 ko00000,ko00001,ko01000 - - - CN_hydrolase BJHFPPGC_01895 904306.HMPREF9192_0370 0.0 2125.0 COG0739@1|root,COG0860@1|root,COG1705@1|root,COG1876@1|root,COG3757@1|root,COG0739@2|Bacteria,COG0860@2|Bacteria,COG1705@2|Bacteria,COG1876@2|Bacteria,COG3757@2|Bacteria,1V1F7@1239|Firmicutes,4ISN5@91061|Bacilli 91061|Bacilli M D-alanyl-D-alanine carboxypeptidase - - 3.4.17.14 ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 M00651 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 - - - GBS_Bsp-like,SH3_5,VanY,YSIRK_signal BJHFPPGC_01897 435842.HMPREF0848_00088 6.56e-292 800.0 COG3290@1|root,COG3290@2|Bacteria,1UYTM@1239|Firmicutes,4HKY4@91061|Bacilli 91061|Bacilli T GHKL domain - - 2.7.13.3 ko:K07706 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c_5 BJHFPPGC_01898 435842.HMPREF0848_00087 3.27e-171 478.0 COG3279@1|root,COG3279@2|Bacteria 2|Bacteria KT phosphorelay signal transduction system agrA - - ko:K07707 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg BJHFPPGC_01899 1167632.AJTR01000114_gene2106 1.05e-70 259.0 COG2911@1|root,COG3266@1|root,COG4372@1|root,COG2911@2|Bacteria,COG3266@2|Bacteria,COG4372@2|Bacteria 2|Bacteria Q Transposase bipA GO:0005575,GO:0005623,GO:0030115,GO:0030312,GO:0044464,GO:0071944 - ko:K00666,ko:K03561,ko:K14645 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko01004,ko02000,ko03110 1.A.30.2.1 - - IAT_beta,YSIRK_signal BJHFPPGC_01900 435842.HMPREF0848_00623 9.44e-34 115.0 COG3464@1|root,COG3464@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 BJHFPPGC_01901 264199.stu1045 1.7e-183 517.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes 1239|Firmicutes L Transposase - - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 BJHFPPGC_01902 1046629.Ssal_00534 8.25e-40 138.0 COG3547@1|root,COG3547@2|Bacteria,1TQP6@1239|Firmicutes,4HDSE@91061|Bacilli 91061|Bacilli L PFAM transposase IS116 IS110 IS902 family - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 BJHFPPGC_01903 1046629.Ssal_00673 0.0 3175.0 COG3064@1|root,COG3583@1|root,COG3064@2|Bacteria,COG3583@2|Bacteria,1TRAR@1239|Firmicutes,4HEH7@91061|Bacilli 91061|Bacilli M signal peptide protein, YSIRK family - - - ko:K08643 - - - - ko00000,ko01000,ko01002 - - - FIVAR,G5,Gram_pos_anchor,Peptidase_M26_C,Peptidase_M26_N,Trypsin_2,YSIRK_signal BJHFPPGC_01904 1046629.Ssal_00675 0.0 1628.0 COG3266@1|root,COG3266@2|Bacteria 2|Bacteria GM domain, Protein - - - - - - - - - - - - Gram_pos_anchor,Laminin_G_3,YSIRK_signal BJHFPPGC_01907 435842.HMPREF0848_01030 2.59e-277 759.0 COG0420@1|root,COG0420@2|Bacteria,1TQY6@1239|Firmicutes,4HAKB@91061|Bacilli 91061|Bacilli L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity sbcD - - ko:K03547 - - - - ko00000,ko03400 - - - Metallophos,SbcD_C BJHFPPGC_01908 1046629.Ssal_00677 0.0 1672.0 COG0419@1|root,COG0419@2|Bacteria,1TPCS@1239|Firmicutes,4H9Q3@91061|Bacilli 91061|Bacilli L ATPase involved in DNA repair sbcC - - ko:K03546 - - - - ko00000,ko03400 - - - AAA_23,AAA_29,SbcCD_C BJHFPPGC_01909 706433.HMPREF9430_01341 1.02e-174 506.0 28ITE@1|root,2Z8SB@2|Bacteria,1V146@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - BJHFPPGC_01910 1408311.JNJM01000016_gene3498 5.7e-67 223.0 29PCN@1|root,30AAW@2|Bacteria,1V1IN@1239|Firmicutes,24GAD@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - BJHFPPGC_01911 264199.stu1392 0.0 1360.0 COG1216@1|root,COG1442@1|root,COG1216@2|Bacteria,COG1442@2|Bacteria,1VATJ@1239|Firmicutes,4HG1M@91061|Bacilli 91061|Bacilli M family 8 - - - - - - - - - - - - Glyco_transf_8,Glycos_transf_2 BJHFPPGC_01912 435842.HMPREF0848_01027 3.47e-269 739.0 COG0201@1|root,COG0201@2|Bacteria,1V59T@1239|Firmicutes,4HH1U@91061|Bacilli 91061|Bacilli U Part of the accessory SecA2 SecY2 system specifically required for export of secY2 - - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY BJHFPPGC_01913 904306.HMPREF9192_1013 0.0 997.0 2CI7G@1|root,2ZBRM@2|Bacteria,1V1BC@1239|Firmicutes,4HKRQ@91061|Bacilli 91061|Bacilli S Accessory Sec system protein Asp1 asp1 - - ko:K12268 - - - - ko00000,ko02044 3.A.5.10 - - Asp1 BJHFPPGC_01914 904306.HMPREF9192_1014 0.0 1004.0 COG1073@1|root,COG1073@2|Bacteria,1TSWW@1239|Firmicutes,4HB1I@91061|Bacilli 91061|Bacilli S Accessory Sec system protein Asp2 asp2 - - ko:K12269 - - - - ko00000,ko02044 3.A.5.10 - - Asp2 BJHFPPGC_01915 904306.HMPREF9192_1015 8.2e-102 295.0 2AFSZ@1|root,315V3@2|Bacteria,1V6D1@1239|Firmicutes,4HS4W@91061|Bacilli 91061|Bacilli S Accessory Sec system protein Asp3 asp3 - - ko:K12270 - - - - ko00000,ko02044 3.A.5.10 - - Sec-ASP3 BJHFPPGC_01916 435842.HMPREF0848_01023 0.0 1515.0 COG0653@1|root,COG0653@2|Bacteria,1TRJA@1239|Firmicutes,4HCH0@91061|Bacilli 91061|Bacilli U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA2 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - SecA_DEAD,SecA_PP_bind,SecA_SW BJHFPPGC_01917 904306.HMPREF9192_1017 0.0 967.0 COG0438@1|root,COG0438@2|Bacteria,1TR6K@1239|Firmicutes,4HGDG@91061|Bacilli 91061|Bacilli M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon gtf1 - 2.4.1.52 ko:K00712 - - - - ko00000,ko01000,ko01003 - GT4 - Glycos_transf_1 BJHFPPGC_01918 904306.HMPREF9192_1018 7.66e-308 841.0 COG0438@1|root,COG0438@2|Bacteria,1TQZR@1239|Firmicutes,4HEYJ@91061|Bacilli 91061|Bacilli M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1 gtf2 - - - - - - - - - - - - BJHFPPGC_01919 1008453.HMPREF9957_1677 3.27e-24 92.0 2AHFC@1|root,317SM@2|Bacteria,1U4KE@1239|Firmicutes,4IEC5@91061|Bacilli,2TQ11@28037|Streptococcus mitis 91061|Bacilli S Accessory secretory protein Sec Asp4 - - - - - - - - - - - - Asp4 BJHFPPGC_01920 585203.SMSK564_1819 3.67e-23 90.5 2DKDD@1|root,3097M@2|Bacteria,1U4K0@1239|Firmicutes,4IEBR@91061|Bacilli,2TQ0I@28037|Streptococcus mitis 91061|Bacilli S Accessory secretory protein Sec, Asp5 - - - - - - - - - - - - Asp5 BJHFPPGC_01921 435842.HMPREF0848_01018 2.26e-243 668.0 COG0438@1|root,COG0438@2|Bacteria,1V6NM@1239|Firmicutes,4HISP@91061|Bacilli 91061|Bacilli M transferase activity, transferring glycosyl groups - - - - - - - - - - - - - BJHFPPGC_01922 435842.HMPREF0848_01016 0.0 1005.0 COG1766@1|root,COG1766@2|Bacteria 2|Bacteria N bacterial-type flagellum-dependent cell motility fliF - 2.1.1.72 ko:K02409,ko:K02410,ko:K03427 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko01000,ko02035,ko02044,ko02048 3.A.6.2,3.A.6.3 - - Antigen_C,FliG_C,FliG_M,Gram_pos_anchor,HsdM_N,MucBP,N6_Mtase,YSIRK_signal,YscJ_FliF,YscJ_FliF_C BJHFPPGC_01923 435842.HMPREF0848_01017 8.43e-98 336.0 COG5295@1|root,COG5295@2|Bacteria 2|Bacteria UW Hep Hag repeat protein sraP - - ko:K18491,ko:K21449 ko04550,map04550 - - - ko00000,ko00001,ko02000,ko03000 1.B.40.2 - - Gram_pos_anchor,YadA_head,YadA_stalk BJHFPPGC_01932 1046629.Ssal_02107 0.0 2855.0 COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,4H9RF@91061|Bacilli 91061|Bacilli L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity polC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.7 ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon BJHFPPGC_01933 1046629.Ssal_02106 2.52e-301 821.0 COG2309@1|root,COG2309@2|Bacteria,1TP65@1239|Firmicutes,4H9W8@91061|Bacilli 91061|Bacilli E COG2309 Leucyl aminopeptidase (aminopeptidase T) pepS - - ko:K19689 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M29 BJHFPPGC_01934 904306.HMPREF9192_0535 1.4e-48 154.0 COG2261@1|root,COG2261@2|Bacteria 2|Bacteria S Transglycosylase associated protein XK27_02060 - - - - - - - - - - - Transgly_assoc BJHFPPGC_01935 1046629.Ssal_02104 1.28e-93 273.0 COG1846@1|root,COG1846@2|Bacteria,1VB3Q@1239|Firmicutes,4HP7J@91061|Bacilli 91061|Bacilli K Transcriptional regulator, marr family - - - - - - - - - - - - MarR BJHFPPGC_01936 904306.HMPREF9192_0533 3.13e-122 349.0 COG0431@1|root,COG0431@2|Bacteria,1VAI8@1239|Firmicutes 1239|Firmicutes S reductase XK27_03570 - - ko:K19784 - - - - ko00000 - - - FMN_red BJHFPPGC_01938 1046629.Ssal_02102 0.0 974.0 COG3634@1|root,COG3634@2|Bacteria,1TPYN@1239|Firmicutes,4H9W1@91061|Bacilli 91061|Bacilli O alkyl hydroperoxide reductase ahpF - - ko:K03387 - - - - ko00000,ko01000 - - - Pyr_redox_2,Thioredoxin_3 BJHFPPGC_01939 1046629.Ssal_02101 4.96e-136 385.0 COG0450@1|root,COG0450@2|Bacteria,1TQU7@1239|Firmicutes,4HA2M@91061|Bacilli 91061|Bacilli O alkyl hydroperoxide reductase ahpC - 1.11.1.15 ko:K03386 ko04214,map04214 - - - ko00000,ko00001,ko01000,ko04147 - - - 1-cysPrx_C,AhpC-TSA BJHFPPGC_01940 1046629.Ssal_02100 2.48e-176 492.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,4H9N5@91061|Bacilli 91061|Bacilli J Belongs to the universal ribosomal protein uS2 family rpsB GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02967 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S2 BJHFPPGC_01941 1046629.Ssal_02098 1.23e-233 644.0 COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,4HBDV@91061|Bacilli 91061|Bacilli J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005623,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS BJHFPPGC_01942 1046629.Ssal_02096 1.39e-106 307.0 COG2426@1|root,COG2426@2|Bacteria,1V3UW@1239|Firmicutes,4HPN6@91061|Bacilli 91061|Bacilli S Putative small multi-drug export protein - - - - - - - - - - - - Sm_multidrug_ex BJHFPPGC_01943 1046629.Ssal_02095 1.92e-97 284.0 COG4463@1|root,COG4463@2|Bacteria,1VAXT@1239|Firmicutes,4HIFT@91061|Bacilli 91061|Bacilli K Belongs to the CtsR family ctsR GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - ko:K03708 - - - - ko00000,ko03000 - - - CtsR BJHFPPGC_01944 904306.HMPREF9192_0525 0.0 1538.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli 91061|Bacilli O Belongs to the ClpA ClpB family clpC GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - ko:K03696 ko01100,map01100 - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N,UVR BJHFPPGC_01945 1046629.Ssal_02093 1.53e-292 800.0 COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,4HBD4@91061|Bacilli 91061|Bacilli M Belongs to the peptidase S11 family dacA GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.16.4 ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 BJHFPPGC_01946 1046629.Ssal_02092 1.64e-286 784.0 COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,4HBD4@91061|Bacilli 91061|Bacilli M Belongs to the peptidase S11 family dacA GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.16.4 ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 BJHFPPGC_01947 1046629.Ssal_02091 0.0 1386.0 COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,4H9Z3@91061|Bacilli 91061|Bacilli J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 BJHFPPGC_01948 1046629.Ssal_02090 1.75e-181 505.0 2F67I@1|root,33YRI@2|Bacteria,1VY65@1239|Firmicutes,4HXHY@91061|Bacilli 91061|Bacilli S SseB protein N-terminal domain - - - - - - - - - - - - SseB BJHFPPGC_01949 1046629.Ssal_02089 4.02e-144 406.0 COG1045@1|root,COG1045@2|Bacteria,1TR42@1239|Firmicutes,4HAKS@91061|Bacilli 91061|Bacilli E serine acetyltransferase cysE - 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - Hexapep BJHFPPGC_01950 904306.HMPREF9192_0518 0.0 882.0 COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,4HA6D@91061|Bacilli 91061|Bacilli J Belongs to the class-I aminoacyl-tRNA synthetase family cysS GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,tRNA-synt_1e,tRNA-synt_1g BJHFPPGC_01951 1046629.Ssal_02085 1.22e-89 263.0 COG1939@1|root,COG1939@2|Bacteria,1VA5V@1239|Firmicutes,4HIM3@91061|Bacilli 91061|Bacilli J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc) mrnC GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 - ko:K11145 - - - - ko00000,ko01000,ko03009 - - - Ribonuclease_3 BJHFPPGC_01953 1046629.Ssal_02082 1.68e-170 476.0 COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,4HBBI@91061|Bacilli 91061|Bacilli J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family trmH GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 ko:K03218 - - - - ko00000,ko01000,ko03009 - - - SpoU_methylase,SpoU_sub_bind BJHFPPGC_01954 1046629.Ssal_02081 1.64e-119 341.0 COG3688@1|root,COG3688@2|Bacteria,1V9XR@1239|Firmicutes,4HFW4@91061|Bacilli 91061|Bacilli S RNA-binding protein containing a PIN domain yacP - - ko:K06962 - - - - ko00000 - - - NYN_YacP BJHFPPGC_01955 1046629.Ssal_02080 7.15e-196 544.0 COG1307@1|root,COG1307@2|Bacteria,1TQDI@1239|Firmicutes,4HAYQ@91061|Bacilli 91061|Bacilli S DegV family yitS - - - - - - - - - - - DegV BJHFPPGC_01957 1046629.Ssal_02078 1.21e-40 134.0 COG1476@1|root,COG1476@2|Bacteria,1VERT@1239|Firmicutes,4HNID@91061|Bacilli 91061|Bacilli K Transcriptional - - - ko:K07729 - - - - ko00000,ko03000 - - - HTH_3 BJHFPPGC_01958 1046629.Ssal_02077 7.02e-103 297.0 COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,4HG0I@91061|Bacilli 91061|Bacilli J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02871 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L13 BJHFPPGC_01959 435842.HMPREF0848_01903 2.12e-84 249.0 COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,4HH3B@91061|Bacilli 91061|Bacilli J Belongs to the universal ribosomal protein uS9 family rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02996 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S9 BJHFPPGC_01960 264199.stu0102 1.95e-236 656.0 COG0582@1|root,COG0582@2|Bacteria,1TRCD@1239|Firmicutes,4HDUS@91061|Bacilli 91061|Bacilli L Belongs to the 'phage' integrase family int - - - - - - - - - - - Phage_integrase BJHFPPGC_01961 1095726.HMPREF1116_1530 6.53e-58 179.0 2DQ86@1|root,33582@2|Bacteria,1VJ5D@1239|Firmicutes,4HP0T@91061|Bacilli 91061|Bacilli S Helix-turn-helix domain - - - - - - - - - - - - HTH_17 BJHFPPGC_01962 888816.HMPREF9389_0186 3.59e-222 618.0 COG3596@1|root,COG3597@1|root,COG3596@2|Bacteria,COG3597@2|Bacteria,1TSZW@1239|Firmicutes,4HAIB@91061|Bacilli,1WRGT@1305|Streptococcus sanguinis 91061|Bacilli S Septin - - - - - - - - - - - - DUF697,MMR_HSR1 BJHFPPGC_01963 888821.HMPREF9394_0459 6.6e-16 72.4 29RRC@1|root,30CV0@2|Bacteria,1UAEK@1239|Firmicutes,4IKSX@91061|Bacilli,1WS7X@1305|Streptococcus sanguinis 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_01964 1114965.Spaf_1839 3.9e-220 612.0 COG3942@1|root,COG3942@2|Bacteria 2|Bacteria S pathogenesis isp2 - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - Big_2,CHAP,GBS_Bsp-like,SLT BJHFPPGC_01965 889204.HMPREF9423_1695 1.49e-40 134.0 2DIZY@1|root,304F2@2|Bacteria,1TWMH@1239|Firmicutes,4I5FA@91061|Bacilli,43GK9@68892|Streptococcus infantis 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_01966 1114965.Spaf_1841 0.0 924.0 2C6HY@1|root,33KT6@2|Bacteria,1VPRF@1239|Firmicutes,4HRNY@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_01967 888833.HMPREF9421_0295 0.0 1595.0 COG0433@1|root,COG0433@2|Bacteria,1TPVQ@1239|Firmicutes,4HDZ5@91061|Bacilli 91061|Bacilli S AAA-like domain yddE GO:0000746,GO:0005575,GO:0005623,GO:0008150,GO:0009291,GO:0009292,GO:0009987,GO:0044464,GO:0044764,GO:0051704,GO:0060187 - - - - - - - - - - AAA_10 BJHFPPGC_01968 888833.HMPREF9421_0296 1.3e-90 265.0 28XX3@1|root,2ZJT6@2|Bacteria,1W2A1@1239|Firmicutes,4HRZR@91061|Bacilli 91061|Bacilli S TcpE family - - - - - - - - - - - - TcpE BJHFPPGC_01969 997830.HMPREF1124_1840 7.96e-45 145.0 2DIZX@1|root,304F1@2|Bacteria,1TWMF@1239|Firmicutes,4I5F8@91061|Bacilli,43GK7@68892|Streptococcus infantis 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_01970 889204.HMPREF9423_1690 4.22e-206 573.0 2DIXX@1|root,304CB@2|Bacteria,1TWH9@1239|Firmicutes,4I5AM@91061|Bacilli,43GA2@68892|Streptococcus infantis 91061|Bacilli S Conjugative transposon protein TcpC - - - - - - - - - - - - TpcC BJHFPPGC_01971 889204.HMPREF9423_1689 2.42e-112 324.0 2DIYR@1|root,304DE@2|Bacteria,1TWIR@1239|Firmicutes,4I5C6@91061|Bacilli,43GCT@68892|Streptococcus infantis 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_01972 997830.HMPREF1124_1837 1.34e-44 144.0 2DIZT@1|root,304EX@2|Bacteria,1TWMB@1239|Firmicutes,4I5F4@91061|Bacilli,43GK2@68892|Streptococcus infantis 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_01973 1316408.HSISM1_2140 1.48e-287 786.0 COG1476@1|root,COG1476@2|Bacteria,1VWK6@1239|Firmicutes,4HWSS@91061|Bacilli 91061|Bacilli K Replication initiation factor - - - - - - - - - - - - HTH_3,Rep_trans BJHFPPGC_01974 888833.HMPREF9421_0302 0.0 955.0 COG1674@1|root,COG1674@2|Bacteria,1TPHE@1239|Firmicutes,4HB44@91061|Bacilli 91061|Bacilli D Ftsk spoiiie family protein ydcQ - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_SpoIIIE BJHFPPGC_01975 889204.HMPREF9423_1685 3.04e-95 278.0 2BH4N@1|root,32B5M@2|Bacteria,1TWII@1239|Firmicutes,4I5BY@91061|Bacilli,43GCF@68892|Streptococcus infantis 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_01976 889204.HMPREF9423_1684 1.59e-55 174.0 2DIYT@1|root,304DG@2|Bacteria,1TWIT@1239|Firmicutes,4I5C8@91061|Bacilli,43GCV@68892|Streptococcus infantis 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_01977 1095726.HMPREF1116_1515 5.33e-61 189.0 COG3620@1|root,COG3620@2|Bacteria,1UKAW@1239|Firmicutes,4IUKM@91061|Bacilli 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3 BJHFPPGC_01978 1506583.JQJY01000004_gene2619 2.89e-07 61.6 2DNU0@1|root,32Z4H@2|Bacteria 2|Bacteria S FRG domain - - - - - - - - - - - - FRG BJHFPPGC_01979 435842.HMPREF0848_01229 1.74e-171 481.0 COG2856@1|root,COG2856@2|Bacteria,1VPKW@1239|Firmicutes,4HZKQ@91061|Bacilli 91061|Bacilli E IrrE N-terminal-like domain - - - - - - - - - - - - Peptidase_M78 BJHFPPGC_01980 1095726.HMPREF1116_0259 1.1e-135 387.0 COG2932@1|root,COG2932@2|Bacteria,1TQWX@1239|Firmicutes,4HY19@91061|Bacilli 91061|Bacilli K Peptidase S24-like protein - - - - - - - - - - - - HTH_3,Peptidase_S24 BJHFPPGC_01981 1046629.Ssal_01236 1.56e-22 91.7 COG2801@1|root,COG3547@1|root,COG2801@2|Bacteria,COG3547@2|Bacteria 2|Bacteria L Transposase (IS116 IS110 IS902 family) - - - ko:K07497 - - - - ko00000 - - - DEDD_Tnp_IS110,Transposase_20 BJHFPPGC_01995 435842.HMPREF0848_01966 4.12e-158 447.0 COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,4HB0K@91061|Bacilli 91061|Bacilli M Involved in formation and maintenance of cell shape mreC GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0022603,GO:0022604,GO:0030428,GO:0042546,GO:0043621,GO:0044085,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944 - ko:K03570 - - - - ko00000,ko03036 9.B.157.1 - - MreC BJHFPPGC_01996 1046629.Ssal_02150 9.73e-109 314.0 COG2891@1|root,COG2891@2|Bacteria,1VEN7@1239|Firmicutes,4HNAD@91061|Bacilli 91061|Bacilli M rod shape-determining protein MreD mreD - - ko:K03571 - - - - ko00000,ko03036 9.B.157.1 - - MreD BJHFPPGC_01997 1046629.Ssal_02149 8.55e-143 425.0 COG3883@1|root,COG3942@1|root,COG3883@2|Bacteria,COG3942@2|Bacteria,1VCXB@1239|Firmicutes,4IS6H@91061|Bacilli 91061|Bacilli S CHAP domain pcsB - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - CHAP BJHFPPGC_01998 1046629.Ssal_02148 5.55e-223 615.0 COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,4HB61@91061|Bacilli 91061|Bacilli F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran_N BJHFPPGC_01999 1046629.Ssal_02145 1.67e-272 746.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli 91061|Bacilli E Aminotransferase araT - - ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R04467 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 BJHFPPGC_02000 904306.HMPREF9192_0004 1.49e-178 498.0 COG1381@1|root,COG1381@2|Bacteria,1UZ19@1239|Firmicutes,4HAHI@91061|Bacilli 91061|Bacilli L Involved in DNA repair and RecF pathway recombination recO GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N BJHFPPGC_02001 1046629.Ssal_02143 3.41e-234 645.0 COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,4HA0R@91061|Bacilli 91061|Bacilli I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA plsX GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FA_synthesis BJHFPPGC_02002 435842.HMPREF0848_01959 2.97e-41 136.0 COG0236@1|root,COG0236@2|Bacteria 2|Bacteria IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP_1 - - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding BJHFPPGC_02003 1046629.Ssal_02141 1.23e-166 466.0 COG0152@1|root,COG0152@2|Bacteria,1TP11@1239|Firmicutes,4H9U8@91061|Bacilli 91061|Bacilli F Belongs to the SAICAR synthetase family purC - 6.3.2.6 ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04591 RC00064,RC00162 ko00000,ko00001,ko00002,ko01000 - - - SAICAR_synt BJHFPPGC_02004 904306.HMPREF9192_0008 0.0 2404.0 COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1TPAS@1239|Firmicutes,4HB3N@91061|Bacilli 91061|Bacilli F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purL - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS_C,GATase_5 BJHFPPGC_02005 435842.HMPREF0848_01956 0.0 943.0 COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,4HAXU@91061|Bacilli 91061|Bacilli F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine purF - 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - iSB619.SA_RS05225 GATase_6,GATase_7,Pribosyltran BJHFPPGC_02006 435842.HMPREF0848_01955 2.26e-242 666.0 COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,4HABW@91061|Bacilli 91061|Bacilli F Phosphoribosylformylglycinamidine cyclo-ligase purM - 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C BJHFPPGC_02007 997830.HMPREF1124_1662 3.13e-128 364.0 COG0299@1|root,COG0299@2|Bacteria,1V3RJ@1239|Firmicutes,4HGY5@91061|Bacilli,43FCA@68892|Streptococcus infantis 91061|Bacilli F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate purN - 2.1.2.2 ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - - Formyl_trans_N BJHFPPGC_02008 1046629.Ssal_02136 0.0 1012.0 COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,4H9YY@91061|Bacilli 91061|Bacilli F Bifunctional purine biosynthesis protein PurH purH - 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AICARFT_IMPCHas,MGS BJHFPPGC_02009 1046629.Ssal_01740 1.75e-198 550.0 COG3942@1|root,COG3942@2|Bacteria,1VUNU@1239|Firmicutes,4HVY0@91061|Bacilli 91061|Bacilli S CHAP domain - - - - - - - - - - - - CHAP,SH3_5 BJHFPPGC_02010 264199.stu0040 5.3e-302 823.0 COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,4HA70@91061|Bacilli 91061|Bacilli F Belongs to the GARS family purD - 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 - - - GARS_A,GARS_C,GARS_N BJHFPPGC_02011 1005705.HMPREF9967_0320 9.6e-106 306.0 COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,4HFR7@91061|Bacilli,43FX6@68892|Streptococcus infantis 91061|Bacilli F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) purE - 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 - - - AIRC BJHFPPGC_02012 904306.HMPREF9192_0016 3.02e-254 698.0 COG0026@1|root,COG0026@2|Bacteria,1TQCD@1239|Firmicutes,4H9M5@91061|Bacilli 91061|Bacilli F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) purK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 - - - 2-Hacid_dh_C,ATP-grasp BJHFPPGC_02013 888833.HMPREF9421_0376 2.63e-222 613.0 COG1893@1|root,COG1893@2|Bacteria,1UD8U@1239|Firmicutes 1239|Firmicutes H Ketopantoate reductase - - 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 - - - ApbA BJHFPPGC_02014 585203.SMSK564_1384 5.13e-46 148.0 2DZH9@1|root,32VAR@2|Bacteria,1VIUY@1239|Firmicutes,4HZSZ@91061|Bacilli,2TPYM@28037|Streptococcus mitis 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_02015 264199.stu0045 3.54e-313 853.0 COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,4HACW@91061|Bacilli 91061|Bacilli F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily purB GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS09895 ADSL_C,Lyase_1 BJHFPPGC_02016 435842.HMPREF0848_01943 0.0 1101.0 COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,4HAR3@91061|Bacilli 91061|Bacilli J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d BJHFPPGC_02017 904306.HMPREF9192_0023 4.46e-89 262.0 COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,4HFY8@91061|Bacilli 91061|Bacilli K Regulates arginine biosynthesis genes argR - - ko:K03402 - - - - ko00000,ko03000 - - - Arg_repressor,Arg_repressor_C BJHFPPGC_02018 1046629.Ssal_02121 2.9e-70 213.0 COG4550@1|root,COG4550@2|Bacteria,1V4W0@1239|Firmicutes,4HH6Y@91061|Bacilli 91061|Bacilli S Belongs to the UPF0342 family ymcA - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - Com_YlbF BJHFPPGC_02019 904306.HMPREF9192_0025 0.0 1620.0 COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,4HA63@91061|Bacilli 91061|Bacilli L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V BJHFPPGC_02020 1046629.Ssal_02119 7.24e-102 295.0 2E0UI@1|root,32WBZ@2|Bacteria,1VHBQ@1239|Firmicutes,4HRYH@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF3021) - - - - - - - - - - - - DUF3021 BJHFPPGC_02021 904306.HMPREF9192_0027 5.15e-90 265.0 COG3279@1|root,COG3279@2|Bacteria,1VE2H@1239|Firmicutes,4IPMG@91061|Bacilli 91061|Bacilli K LytTr DNA-binding domain - - - - - - - - - - - - LytTR BJHFPPGC_02023 1046629.Ssal_02116 0.0 1236.0 COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,4HB34@91061|Bacilli 91061|Bacilli L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C BJHFPPGC_02025 1046629.Ssal_02114 1.78e-133 379.0 COG0632@1|root,COG0632@2|Bacteria,1V3KF@1239|Firmicutes,4HHI5@91061|Bacilli 91061|Bacilli L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB ruvA - 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N BJHFPPGC_02026 904306.HMPREF9192_0031 3.08e-134 380.0 COG2818@1|root,COG2818@2|Bacteria,1V9B8@1239|Firmicutes,4HJ4I@91061|Bacilli 91061|Bacilli L 3-methyladenine DNA glycosylase tag - 3.2.2.20 ko:K01246 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Adenine_glyco BJHFPPGC_02027 1046629.Ssal_02112 3.22e-288 789.0 COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,4HATN@91061|Bacilli 91061|Bacilli S Belongs to the CinA family cinA - 3.5.1.42 ko:K03742,ko:K03743 ko00760,map00760 - R02322 RC00100 ko00000,ko00001,ko01000 - - - CinA,MoCF_biosynth BJHFPPGC_02028 1046629.Ssal_02111 4.16e-260 714.0 COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,4HAG5@91061|Bacilli 91061|Bacilli L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA BJHFPPGC_02029 435842.HMPREF0848_01930 8.92e-87 255.0 COG1393@1|root,COG1393@2|Bacteria,1VYBB@1239|Firmicutes,4HWYC@91061|Bacilli 91061|Bacilli P Belongs to the ArsC family spxA_2 - 1.20.4.1 ko:K00537,ko:K16509 - - - - ko00000,ko01000 - - - ArsC,Glutaredoxin BJHFPPGC_02031 996306.SSUR61_1115 2.66e-261 765.0 2C4IS@1|root,2Z81U@2|Bacteria,1TSSF@1239|Firmicutes,4HC39@91061|Bacilli 91061|Bacilli S Lantibiotic dehydratase, C terminus bsaB - - ko:K20483 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001 - - - Lant_dehydr_C,Lant_dehydr_N BJHFPPGC_02032 996306.SSUR61_1114 1.51e-216 622.0 COG1132@1|root,COG1132@2|Bacteria,1TPZP@1239|Firmicutes,4HDMH@91061|Bacilli,1WTU9@1307|Streptococcus suis 91061|Bacilli V ATPases associated with a variety of cellular activities nisT - - ko:K06147,ko:K20485 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001,ko02000 3.A.1.106,3.A.1.109,3.A.1.111.2,3.A.1.111.3,3.A.1.21 - - ABC_membrane,ABC_tran BJHFPPGC_02033 1214217.ALNF01000037_gene337 8.68e-107 328.0 COG4403@1|root,COG4403@2|Bacteria,1V13V@1239|Firmicutes,4HFSX@91061|Bacilli,1WTUW@1307|Streptococcus suis 91061|Bacilli V Lanthionine synthetase C-like protein spaC1 - - ko:K20484 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001 - - - LANC_like BJHFPPGC_02035 862967.SIR_0968 1.72e-160 476.0 COG1404@1|root,COG1404@2|Bacteria,1TS1X@1239|Firmicutes,4HHV1@91061|Bacilli 91061|Bacilli O Subtilase family - - - ko:K20486 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S8 BJHFPPGC_02036 862967.SIR_0967 1.9e-107 315.0 COG0745@1|root,COG0745@2|Bacteria,1TQ0D@1239|Firmicutes,4HDA9@91061|Bacilli 91061|Bacilli KT Transcriptional regulatory protein, C terminal spaR - - ko:K20488 ko02020,ko02024,map02020,map02024 M00816 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C BJHFPPGC_02037 862967.SIR_0966 2.37e-125 378.0 COG0642@1|root,COG0642@2|Bacteria,1VXY5@1239|Firmicutes 1239|Firmicutes T His Kinase A (phosphoacceptor) domain - - 2.7.13.3 ko:K20487 ko02020,ko02024,map02020,map02024 M00816 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA BJHFPPGC_02038 1123318.KB904627_gene2183 5.92e-153 445.0 COG3039@1|root,COG3039@2|Bacteria,1TPFS@1239|Firmicutes,4HD09@91061|Bacilli 91061|Bacilli L Transposase - - - - - - - - - - - - DDE_Tnp_1,DDE_Tnp_1_6,DUF772 BJHFPPGC_02040 862967.SIR_0964 1.32e-68 218.0 COG4200@1|root,COG4200@2|Bacteria 2|Bacteria V ABC-2 family transporter protein - - - ko:K20491 ko02010,ko02020,ko02024,map02010,map02020,map02024 M00817 - - ko00000,ko00001,ko00002,ko02000 3.A.1.124.1,3.A.1.124.2,3.A.1.124.6 - - ABC2_membrane_4 BJHFPPGC_02041 1069533.Sinf_0951 2.18e-106 313.0 COG1131@1|root,COG1131@2|Bacteria,1VVRQ@1239|Firmicutes,4HWA2@91061|Bacilli 91061|Bacilli V AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K01990,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 M00254,M00817 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.124.1,3.A.1.124.2,3.A.1.124.6 - - ABC_tran BJHFPPGC_02043 1316408.HSISM1_434 6.35e-131 373.0 COG4300@1|root,COG4300@2|Bacteria 2|Bacteria P Cadmium resistance transporter cadD - - - - - - - - - - - Cad BJHFPPGC_02044 1000588.HMPREF9965_2027 4.42e-73 219.0 COG0640@1|root,COG0640@2|Bacteria,1VBPB@1239|Firmicutes,4HMSR@91061|Bacilli,2TPTX@28037|Streptococcus mitis 91061|Bacilli K Bacterial regulatory protein, arsR family cadX - - ko:K21903 - - - - ko00000,ko03000 - - - HTH_5 BJHFPPGC_02045 888816.HMPREF9389_0203 2.35e-23 89.0 2DWE2@1|root,33ZW2@2|Bacteria,1VY1Y@1239|Firmicutes,4HX5Y@91061|Bacilli,1WS0Z@1305|Streptococcus sanguinis 91061|Bacilli - - - - - - - - - - - - - - - BJHFPPGC_02046 1114965.Spaf_0451 4.73e-63 196.0 COG3548@1|root,COG3548@2|Bacteria 2|Bacteria S protein homotetramerization yiiE - - - - - - - - - - - DUF1211 BJHFPPGC_02048 1046629.Ssal_02065 3.02e-40 133.0 COG1476@1|root,COG1476@2|Bacteria,1VEGF@1239|Firmicutes,4IPKE@91061|Bacilli 91061|Bacilli K Helix-turn-helix domain - - - ko:K07729 - - - - ko00000,ko03000 - - - HTH_3 BJHFPPGC_02050 435842.HMPREF0848_01916 2.05e-191 532.0 COG4509@1|root,COG4509@2|Bacteria,1V2FT@1239|Firmicutes,4IQ4U@91061|Bacilli 91061|Bacilli S Sortase family srtB - - - - - - - - - - - Sortase BJHFPPGC_02051 1046629.Ssal_02062 4.97e-294 802.0 COG2843@1|root,COG2843@2|Bacteria,1UZW4@1239|Firmicutes,4HBC3@91061|Bacilli 91061|Bacilli M Bacterial capsule synthesis protein capA - - ko:K07282 - - - - ko00000 - - - PGA_cap BJHFPPGC_02052 1046629.Ssal_02061 4.16e-51 162.0 COG3830@1|root,COG3830@2|Bacteria,1VENW@1239|Firmicutes,4HNJ4@91061|Bacilli 91061|Bacilli T UPF0237 protein XK27_08630 - - ko:K07166 - - - - ko00000 - - - ACT_6 BJHFPPGC_02053 904306.HMPREF9192_0489 8.59e-307 838.0 COG2848@1|root,COG2848@2|Bacteria,1TQG8@1239|Firmicutes,4HBTU@91061|Bacilli 91061|Bacilli S UPF0210 protein XK27_08635 - - ko:K09157 - - - - ko00000 - - - DUF711 BJHFPPGC_02054 904306.HMPREF9192_0488 1.19e-168 471.0 COG0406@1|root,COG0406@2|Bacteria,1VDCB@1239|Firmicutes,4HJ9X@91061|Bacilli 91061|Bacilli G Phosphoglycerate mutase gpmB - - ko:K15640 - - - - ko00000 - - - His_Phos_1 BJHFPPGC_02055 1046629.Ssal_02058 2.37e-179 500.0 COG1876@1|root,COG1876@2|Bacteria,1V1F7@1239|Firmicutes,4HBR1@91061|Bacilli 91061|Bacilli M D-alanyl-D-alanine carboxypeptidase yodJ - 3.4.16.4,3.4.17.14 ko:K01286,ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 M00651 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 - - - VanY BJHFPPGC_02056 1046629.Ssal_02057 9.58e-130 369.0 COG1705@1|root,COG1705@2|Bacteria,1V7JY@1239|Firmicutes,4HIY4@91061|Bacilli 91061|Bacilli NU Muramidase (Flagellum-specific) acmA - 3.2.1.17,3.2.1.96 ko:K01185,ko:K01227 ko00511,map00511 - - - ko00000,ko00001,ko01000 - - - Glucosaminidase,SH3_8,YceG BJHFPPGC_02057 904306.HMPREF9192_0485 5.71e-238 655.0 COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,4HAX5@91061|Bacilli 91061|Bacilli K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons hrcA GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K03705 - - - - ko00000,ko03000 - - - HrcA,HrcA_DNA-bdg BJHFPPGC_02058 1046629.Ssal_02055 2.44e-105 306.0 COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,4HIRK@91061|Bacilli 91061|Bacilli O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ grpE GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - ko:K03687 - - - - ko00000,ko03029,ko03110 - - - GrpE BJHFPPGC_02059 1046629.Ssal_02054 0.0 1127.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,4HA9S@91061|Bacilli 91061|Bacilli O Heat shock 70 kDa protein dnaK GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:0051704,GO:0098630,GO:0098743,GO:2001065 - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 BJHFPPGC_02060 904306.HMPREF9192_0482 3.4e-257 707.0 COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,4H9KA@91061|Bacilli 91061|Bacilli O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ - - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG BJHFPPGC_02061 1046629.Ssal_02051 8.7e-178 495.0 COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,4HCFI@91061|Bacilli 91061|Bacilli J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs truA GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 BJHFPPGC_02062 904306.HMPREF9192_0479 2.89e-174 486.0 COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,4H9PP@91061|Bacilli 91061|Bacilli H phosphomethylpyrimidine kinase thiD - 2.7.1.35 ko:K00868 ko00750,ko01100,map00750,map01100 - R00174,R01909,R02493 RC00002,RC00017 ko00000,ko00001,ko01000 - - - Phos_pyr_kin BJHFPPGC_02063 1046629.Ssal_02049 6.11e-106 306.0 COG4720@1|root,COG4720@2|Bacteria,1VBBN@1239|Firmicutes,4HNM0@91061|Bacilli 91061|Bacilli S cog cog4720 hmpT - - - - - - - - - - - ECF-ribofla_trS BJHFPPGC_02065 585202.SMSK321_1115 1.94e-128 390.0 COG0392@1|root,COG2898@1|root,COG0392@2|Bacteria,COG2898@2|Bacteria,1TQI2@1239|Firmicutes,4HBHU@91061|Bacilli,2TQ66@28037|Streptococcus mitis 91061|Bacilli S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms mprF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.2.3 ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00726 - - ko00000,ko00001,ko00002,ko01000,ko01504 2.A.1.3.37 - iYO844.BG12900 DUF2156,LPG_synthase_TM BJHFPPGC_02066 1005704.HMPREF9968_1464 2.49e-206 573.0 COG0679@1|root,COG0679@2|Bacteria,1UY4N@1239|Firmicutes,4HDX5@91061|Bacilli,1WQ0P@1303|Streptococcus oralis 91061|Bacilli S Sodium Bile acid symporter family mleP - - ko:K07088 - - - - ko00000 - - - Mem_trans BJHFPPGC_02067 1005704.HMPREF9968_1465 0.0 1060.0 COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,4HBF1@91061|Bacilli,1WQ0I@1303|Streptococcus oralis 91061|Bacilli C Malic enzyme, NAD binding domain mleS - 1.1.1.38,4.1.1.101 ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 - R00214,R11074 RC00105,RC00282 ko00000,ko00001,ko01000 - - - Malic_M,malic BJHFPPGC_02068 467705.SGO_0371 1.69e-63 195.0 COG1396@1|root,COG1396@2|Bacteria,1VK84@1239|Firmicutes,4HN0W@91061|Bacilli 91061|Bacilli K Helix-turn-helix - - - - - - - - - - - - HTH_19,HTH_3 BJHFPPGC_02069 388919.SSA_0295 2.59e-150 429.0 COG0583@1|root,COG0583@2|Bacteria,1V5VW@1239|Firmicutes,4HHDY@91061|Bacilli,1WQQZ@1305|Streptococcus sanguinis 91061|Bacilli K malolactic fermentation system mleR - - - - - - - - - - - HTH_1,LysR_substrate BJHFPPGC_02070 1046629.Ssal_00722 1.74e-154 436.0 28MHE@1|root,2ZAUA@2|Bacteria,1V3A5@1239|Firmicutes,4HZB2@91061|Bacilli 91061|Bacilli S CAAX protease self-immunity - - - - - - - - - - - - Abi BJHFPPGC_02071 1046629.Ssal_00721 3.24e-294 807.0 COG0477@1|root,COG2814@2|Bacteria 2|Bacteria EGP Major facilitator Superfamily - - - ko:K18926 - M00715 - - ko00000,ko00002,ko02000 2.A.1.3.30 - - MFS_1 BJHFPPGC_02072 1046629.Ssal_00720 2.62e-81 242.0 COG1846@1|root,COG1846@2|Bacteria,1VEYN@1239|Firmicutes 1239|Firmicutes K Transcriptional regulator, MarR family - - - - - - - - - - - - MarR,MarR_2 BJHFPPGC_02073 1046629.Ssal_00719 1.8e-124 355.0 COG0110@1|root,COG0110@2|Bacteria,1TQEX@1239|Firmicutes,4HAJ0@91061|Bacilli 91061|Bacilli GK Maltose O-acetyltransferase maa - 2.3.1.79 ko:K00661 - - - - ko00000,ko01000 - - - CM_2,Hexapep,Hexapep_2,Mac BJHFPPGC_02074 904306.HMPREF9192_1436 1.51e-78 252.0 COG0642@1|root,COG0642@2|Bacteria 2|Bacteria T Histidine kinase - - 2.7.13.3 ko:K10681,ko:K20487 ko02020,ko02024,map02020,map02024 M00468,M00816 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA BJHFPPGC_02075 1095726.HMPREF1116_1842 7.78e-93 278.0 COG0745@1|root,COG0745@2|Bacteria,1V5S4@1239|Firmicutes,4IQ3S@91061|Bacilli 91061|Bacilli K Transcriptional regulatory protein, C terminal nisR - - ko:K20488 ko02020,ko02024,map02020,map02024 M00816 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C BJHFPPGC_02077 1437608.BBIA_1578 1.82e-18 90.1 2B6YP@1|root,31ZYT@2|Bacteria,2H32T@201174|Actinobacteria,4D1XQ@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BJHFPPGC_02078 1114965.Spaf_1095 4.35e-112 328.0 COG1131@1|root,COG1131@2|Bacteria,1TSUA@1239|Firmicutes,4HEHW@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - AAA_21,ABC_tran BJHFPPGC_02079 1046629.Ssal_00718 3.38e-171 478.0 COG2220@1|root,COG2220@2|Bacteria 2|Bacteria S N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - - - - - - - - - - Lactamase_B_2,Lactamase_B_3 BJHFPPGC_02080 1046629.Ssal_00717 0.0 2580.0 COG3266@1|root,COG4932@1|root,COG3266@2|Bacteria,COG4932@2|Bacteria 2|Bacteria M domain protein - - 3.5.1.28 ko:K01448,ko:K13733,ko:K20276 ko01503,ko02024,ko05100,map01503,map02024,map05100 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - CHU_C,Gram_pos_anchor,MucBP,SLH BJHFPPGC_02081 1046629.Ssal_00714 0.0 2653.0 COG0366@1|root,COG5263@1|root,COG0366@2|Bacteria,COG5263@2|Bacteria,1VQXK@1239|Firmicutes,4HEIA@91061|Bacilli 91061|Bacilli M KxYKxGKxW signal domain protein - GO:0005575,GO:0005576 2.4.1.5 ko:K00689 ko00500,ko02020,map00500,map02020 - R02120,R06066 RC00028 ko00000,ko00001,ko01000 - GH13 - Big_2,CW_binding_1,Glyco_hydro_70 BJHFPPGC_02085 435842.HMPREF0848_01038 0.0 3351.0 COG4932@1|root,COG4932@2|Bacteria 2|Bacteria M domain protein - - - - - - - - - - - - Cna_B,FctA,Gram_pos_anchor,YSIRK_signal BJHFPPGC_02089 322159.STER_0016 4.72e-91 270.0 COG2963@1|root,COG2963@2|Bacteria,1W68S@1239|Firmicutes 1239|Firmicutes L Transposase - - - - - - - - - - - - HTH_Tnp_1 BJHFPPGC_02090 1316408.HSISM1_1539 4.69e-177 496.0 COG2801@1|root,COG2801@2|Bacteria,1TQQY@1239|Firmicutes,4HC8M@91061|Bacilli 91061|Bacilli L Transposase and inactivated derivatives - - - ko:K07497 - - - - ko00000 - - - HTH_21,HTH_28,rve,rve_2 BJHFPPGC_02091 1158609.I586_02327 1.11e-10 57.8 2ESJ7@1|root,33K3X@2|Bacteria 2|Bacteria S Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores - - - ko:K20482 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001,ko02000 1.C.20 - - Gallidermin ## 1863 queries scanned ## Total time (seconds): 1.7623214721679688 ## Rate: 1057.13 q/s