GCA_047528675.1 - 18 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

gnlProkkaCBIBJKBG_1 (original name was: gnl|Prokka|CBIBJKBG_1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1.1	T3PKS	906,954	948,051	1-carbapen-2-em-3-carboxylic acid	Other	16%
Region 1.2	terpene	1,119,951	1,141,849
Region 1.3	NRPS	1,212,300	1,235,855	plipastatin	NRP	46%

gnlProkkaCBIBJKBG_2 (original name was: gnl|Prokka|CBIBJKBG_2)

Region	Type	From	To	Most similar known cluster		Similarity
Region 2.1	epipeptide	75,631	97,329	thailanstatin A	NRP+Polyketide	10%
Region 2.2	RiPP-like	112,575	125,306
Region 2.3	other	326,786	368,204	bacilysin	Other	100%
Region 2.4	sactipeptide	375,289	396,900	subtilosin A	RiPP:Thiopeptide	100%
Region 2.5	CDPS	621,554	642,300	pulcherriminic acid	Other	100%
Region 2.6	lanthipeptide-class-i	761,329	787,554	subtilin	RiPP:Lanthipeptide	100%
Region 2.7	NRP-metallophore,NRPS	933,784	985,561	bacillibactin	NRP	100%

gnlProkkaCBIBJKBG_3 (original name was: gnl|Prokka|CBIBJKBG_3)

Region	Type	From	To	Most similar known cluster		Similarity
Region 3.1	NRPS,betalactone	1	38,546	fengycin	NRP	80%
Region 3.2	transAT-PKS,NRPS,T3PKS,PKS-like	100,968	215,753	bacillaene	Polyketide+NRP	100%
Region 3.3	lanthipeptide-class-i	237,980	264,275
Region 3.4	terpene	815,842	836,645

gnlProkkaCBIBJKBG_5 (original name was: gnl|Prokka|CBIBJKBG_5)

Region	Type	From	To	Most similar known cluster		Similarity
Region 5.1	NRPS	1	26,815	surfactin	NRP:Lipopeptide	43%

gnlProkkaCBIBJKBG_6 (original name was: gnl|Prokka|CBIBJKBG_6)

Region	Type	From	To	Most similar known cluster		Similarity
Region 6.1	NRPS	172,783	200,433	surfactin	NRP:Lipopeptide	43%

gnlProkkaCBIBJKBG_10 (original name was: gnl|Prokka|CBIBJKBG_10)

Region	Type	From	To	Most similar known cluster		Similarity
Region 10.1	NRPS	1	14,176	plipastatin	NRP	23%

gnlProkkaCBIBJKBG_11 (original name was: gnl|Prokka|CBIBJKBG_11)

Region	Type	From	To	Most similar known cluster		Similarity
Region 11.1	NRPS	1	9,243	surfactin	NRP:Lipopeptide	8%

Compact view

gnlProkkaCBIBJKBG_1 - Region 1 - T3PKS

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Location: 906,954 - 948,051 nt. (total: 41,098 nt) Show pHMM detection rules used

T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

NRPS/PKS substrates

NRPS/PKS substrate predictions

gnlProkkaCBIBJKBG_1 - Region 2 - terpene

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Location: 1,119,951 - 1,141,849 nt. (total: 21,899 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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core biosynthetic genes

additional biosynthetic genes

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resistance

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaCBIBJKBG_1 - Region 3 - NRPS

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Location: 1,212,300 - 1,235,855 nt. (total: 23,556 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

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transport-related genes

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resistance

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NRPS/PKS domains

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters from MIBiG 3.1

Module view

Legend

NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 3, location 1212299 - 1235855:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Glu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg1_1370

Search NORINE for peptide: strict or relaxed

AMP-binding (463..864): Glu

nrpys: Glu

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: glu,gln (Glu, Gln)
Single AA prediction:: glu (Glu)

Stachelhaus prediction details:

Stachelhaus sequence:: DAWHFGGVDK
Nearest Stachelhaus code(s):: Glu DAWHFGGVDK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

gnlProkkaCBIBJKBG_2 - Region 1 - epipeptide

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Location: 75,631 - 97,329 nt. (total: 21,699 nt) Show pHMM detection rules used

epipeptide: (TIGR04078 and yydH)

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core biosynthetic genes

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

gnlProkkaCBIBJKBG_2 - Region 2 - RiPP-like

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Location: 112,575 - 125,306 nt. (total: 12,732 nt) Show pHMM detection rules used

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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resistance

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaCBIBJKBG_2 - Region 3 - other

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Location: 326,786 - 368,204 nt. (total: 41,419 nt) Show pHMM detection rules used

other: (LmbU or Neocarzinostat or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin or orf2_PTase)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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resistance

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

gnlProkkaCBIBJKBG_2 - Region 4 - sactipeptide

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Location: 375,289 - 396,900 nt. (total: 21,612 nt) Show pHMM detection rules used

sactipeptide: (subtilosin or thuricin or TIGR04404 or Subtilosin_A or skfc)

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core biosynthetic genes

additional biosynthetic genes

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resistance

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Sactipeptides

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

Sactipeptide predictions

Sactipeptide(s) for ctg2_388

ctg2_388

Leader:

MKKAVIVENK

Core:

GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG

antiSMASH-DB 4.0 matches for ctg2_388

100.0% NC_000964.3and 235 others:

NC_014479.1 Sactipeptides: BSUW23_RS18740_sactipeptideNC_014639.1 Sactipeptides: BATR1942_RS15950_sactipeptideNC_014976.1 Sactipeptides: BSN5_RS09700_sactipeptideNC_016047.1 Sactipeptides: GYO_RS41165_sactipeptideNC_017195.1 Sactipeptides: I33_RS18040_sactipeptideNC_017743.1 Sactipeptides: MY9_RS18920_sactipeptideNC_019896.1 Sactipeptides: A7A1_RS01935_sactipeptideNC_020244.1 Sactipeptides: C663_RS18295_sactipeptideNZ_BDDH01000003.1 Sactipeptides: A7P71_RS10610_sactipeptideNZ_CABIVP010000002.1 Sactipeptides: FY199_RS09010_sactipeptideNZ_CP007409.1 Sactipeptides: Q433_RS18950_sactipeptideNZ_CP009796.1 Sactipeptides: OB04_RS19085_sactipeptideNZ_CP011101.1 Sactipeptides: bslm_RS18365_sactipeptideNZ_CP011534.1 Sactipeptides: ABA10_RS18725_sactipeptideNZ_CP011802.1 Sactipeptides: D068_RS17505_sactipeptideNZ_CP016767.1 Sactipeptides: BCV50_RS14935_sactipeptideNZ_CP017072.1 Sactipeptides: BGM23_RS02945_sactipeptideNZ_CP017112.1 Sactipeptides: BS16045_RS19810_sactipeptideNZ_CP017313.1 Sactipeptides: BH660_RS14630_sactipeptideNZ_CP017314.1 Sactipeptides: BSBS38_RS19215_sactipeptideNZ_CP017676.1 Sactipeptides: BKN48_RS08085_sactipeptideNZ_CP018173.1 Sactipeptides: BAX60_RS03615_sactipeptideNZ_CP020367.1 Sactipeptides: BSK2_RS19060_sactipeptideNZ_CP020722.1 Sactipeptides: B7470_RS09560_sactipeptideNZ_CP020915.1 Sactipeptides: B9L64_RS11255_sactipeptideNZ_CP021169.1 Sactipeptides: B9N48_RS18685_sactipeptideNZ_CP021498.1 Sactipeptides: S101444_RS19170_sactipeptideNZ_CP021892.1 Sactipeptides: S100333_RS19720_sactipeptideNZ_CP021903.1 Sactipeptides: CD007_RS18975_sactipeptideNZ_CP021911.1 Sactipeptides: CDO84_RS18225_sactipeptideNZ_CP021921.1 Sactipeptides: S101392_RS19440_sactipeptideNZ_CP022391.1 Sactipeptides: CFK25_RS18875_sactipeptideNZ_CP022890.1 Sactipeptides: CJZ70_RS01210_sactipeptideNZ_CP023257.1 Sactipeptides: CLD04_RS19470_sactipeptideNZ_CP023409.1 Sactipeptides: Bateq7PJ16_RS20450_sactipeptideNZ_CP025941.1 Sactipeptides: C0W65_RS07300_sactipeptideNZ_CP026010.1 Sactipeptides: BS11774_RS03710_sactipeptideNZ_CP026030.1 Sactipeptides: C2H91_RS12110_sactipeptideNZ_CP026035.1 Sactipeptides: C2H96_RS13375_sactipeptideNZ_CP026036.1 Sactipeptides: C2H93_RS16885_sactipeptideNZ_CP026521.1 Sactipeptides: C1T29_RS22385_sactipeptideNZ_CP028201.1 Sactipeptides: C7M16_RS17535_sactipeptideNZ_CP028202.1 Sactipeptides: C7M17_RS17600_sactipeptideNZ_CP028217.1 Sactipeptides: C7M29_RS06900_sactipeptideNZ_CP028218.1 Sactipeptides: C7M30_RS12605_sactipeptideNZ_CP028812.1 Sactipeptides: DAE22_RS20770_sactipeptideNZ_CP029364.1 Sactipeptides: DIC78_RS12275_sactipeptideNZ_CP029461.1 Sactipeptides: DJ572_RS18795_sactipeptideNZ_CP029465.1 Sactipeptides: DKG76_RS19825_sactipeptideNZ_CP029609.1 Sactipeptides: DL538_RS20030_sactipeptideNZ_CP031675.1 Sactipeptides: DYS67_RS19275_sactipeptideNZ_CP031783.1 Sactipeptides: D0808_RS00710_sactipeptideNZ_CP031784.1 Sactipeptides: D0819_RS14700_sactipeptideNZ_CP032853.1 Sactipeptides: D9C10_RS17955_sactipeptideNZ_CP032855.1 Sactipeptides: D9C11_RS09165_sactipeptideNZ_CP035161.1 Sactipeptides: EQH88_RS19675_sactipeptideNZ_CP035167.1 Sactipeptides: EQJ08_RS19095_sactipeptideNZ_CP035226.1 Sactipeptides: EQW70_RS20085_sactipeptideNZ_CP035231.1 Sactipeptides: EQZ01_RS19685_sactipeptideNZ_CP035391.1 Sactipeptides: ES965_RS19370_sactipeptideNZ_CP035395.1 Sactipeptides: ES968_RS19740_sactipeptideNZ_CP035401.1 Sactipeptides: ETA19_RS19595_sactipeptideNZ_CP035402.1 Sactipeptides: ES969_RS19660_sactipeptideNZ_CP035403.1 Sactipeptides: ETA15_RS19805_sactipeptideNZ_CP035406.1 Sactipeptides: ETK61_RS20735_sactipeptideNZ_CP035413.1 Sactipeptides: ETL58_RS19505_sactipeptideNZ_CP039935.1 Sactipeptides: FCJ76_RS19255_sactipeptideNZ_CP045006.1 Sactipeptides: F9B13_RS01950_sactipeptideNZ_CP045425.1 Sactipeptides: GCU76_RS20710_sactipeptideNZ_CP045816.1 Sactipeptides: GII86_RS19920_sactipeptideNZ_CP045824.1 Sactipeptides: GII78_RS20125_sactipeptideNZ_CP046591.1 Sactipeptides: GO004_RS15965_sactipeptideNZ_CP046860.1 Sactipeptides: GPJ55_RS11605_sactipeptideNZ_CP047645.1 Sactipeptides: GSN02_RS19265_sactipeptideNZ_CP049924.1 Sactipeptides: G4G26_RS18960_sactipeptideNZ_CP050705.1 Sactipeptides: HCU65_RS18920_sactipeptideNZ_CP051462.1 Sactipeptides: HC662_RS19240_sactipeptideNZ_CP051464.1 Sactipeptides: HC660_RS18970_sactipeptideNZ_CP054050.1 Sactipeptides: HNV25_RS02005_sactipeptideNZ_CP054177.1 Sactipeptides: HR084_RS18935_sactipeptideNZ_CP054584.1 Sactipeptides: HT135_RS19775_sactipeptideNZ_CP060193.1 Sactipeptides: H7F27_RS02180_sactipeptideNZ_CP060417.1 Sactipeptides: H8S71_RS18495_sactipeptideNZ_CP061284.1 Sactipeptides: ICJ61_RS19715_sactipeptideNZ_CP061870.1 Sactipeptides: IE382_RS22305_sactipeptideNZ_CP062497.1 Sactipeptides: IHV08_RS19770_sactipeptideNZ_CP063276.1 Sactipeptides: IM743_RS18070_sactipeptideNZ_CP065858.1 Sactipeptides: I7X10_RS03370_sactipeptideNZ_CP069789.1 Sactipeptides: JR441_RS19085_sactipeptideNZ_CP070483.1 Sactipeptides: JQX68_RS19175_sactipeptideNZ_CP070976.1 Sactipeptides: JYG31_RS19675_sactipeptideNZ_CP071043.1 Sactipeptides: JS609_RS19245_sactipeptideNZ_CP073265.1 Sactipeptides: KCX77_RS18900_sactipeptideNZ_CP075344.1 Sactipeptides: KIL00_RS20100_sactipeptideNZ_CP076083.1 Sactipeptides: KFF76_RS18635_sactipeptideNZ_CP079759.1 Sactipeptides: KXZ66_RS19695_sactipeptideNZ_CP080508.1 Sactipeptides: K0V03_RS08595_sactipeptideNZ_CP089148.1 Sactipeptides: LRO88_RS20980_sactipeptideNZ_CP090125.1 Sactipeptides: LXE94_RS19505_sactipeptideNZ_CP093289.1 Sactipeptides: MNG38_RS19730_sactipeptideNZ_CP093546.1 Sactipeptides: MOW04_RS19180_sactipeptideNZ_CP095736.1 Sactipeptides: MX663_RS20090_sactipeptideNZ_CP096590.1 Sactipeptides: M0696_RS18995_sactipeptideNZ_CP096889.1 Sactipeptides: EFK13_RS19225_sactipeptideNZ_CP098738.1 Sactipeptides: NDR85_RS18965_sactipeptideNZ_CP100651.1 Sactipeptides: NLW79_RS19990_sactipeptideNZ_CP100752.1 Sactipeptides: NLV76_RS19060_sactipeptideNZ_CP101718.1 Sactipeptides: NPA28_RS19075_sactipeptideNZ_CP101936.1 Sactipeptides: NP434_RS18980_sactipeptideNZ_CP103352.1 Sactipeptides: NX823_RS19780_sactipeptideNZ_CP104878.1 Sactipeptides: N8A75_RS20105_sactipeptideNZ_CP107539.1 Sactipeptides: OEG95_RS19105_sactipeptideNZ_CP110264.1 Sactipeptides: OMK57_RS18975_sactipeptideNZ_CP114899.1 Sactipeptides: O6U12_RS19480_sactipeptideNZ_CP116773.1 Sactipeptides: PNF29_RS01990_sactipeptideNZ_FTMW01000001.1 Sactipeptides: BW968_RS02045_sactipeptideNZ_JAAUXF010000005.1 Sactipeptides: HC742_RS19325_sactipeptideNZ_JABRUZ010000003.1 Sactipeptides: HRF55_RS03085_sactipeptideNZ_JABRVH010000018.1 Sactipeptides: HRF53_RS09100_sactipeptideNZ_JABUKD010000002.1 Sactipeptides: HRW04_RS09345_sactipeptideNZ_JAEACL010000001.1 Sactipeptides: I5F14_RS00800_sactipeptideNZ_JAHVOC010000002.1 Sactipeptides: KXD37_RS07830_sactipeptideNZ_JAJFDG010000003.1 Sactipeptides: LJF29_RS11575_sactipeptideNZ_JAJHUI010000011.1 Sactipeptides: LK399_RS16325_sactipeptideNZ_JALAJC010000012.1 Sactipeptides: MOB18_RS16080_sactipeptideNZ_JALAKW010000005.1 Sactipeptides: MOB93_RS12665_sactipeptideNZ_JALAKZ010000001.1 Sactipeptides: MOB76_RS02240_sactipeptideNZ_JALALA010000011.1 Sactipeptides: MOB82_RS15020_sactipeptideNZ_JALALE010000020.1 Sactipeptides: MOB33_RS20855_sactipeptideNZ_JALALO010000006.1 Sactipeptides: MOB75_RS09230_sactipeptideNZ_JALAMD010000002.1 Sactipeptides: MOB22_RS02315_sactipeptideNZ_JALAME010000005.1 Sactipeptides: MOC02_RS13805_sactipeptideNZ_JALAMJ010000012.1 Sactipeptides: MOB80_RS16635_sactipeptideNZ_JALAMO010000007.1 Sactipeptides: MOB98_RS08535_sactipeptideNZ_JALAMR010000019.1 Sactipeptides: MOC09_RS17975_sactipeptideNZ_JALAMZ010000002.1 Sactipeptides: MOC43_RS01370_sactipeptideNZ_JALANN010000012.1 Sactipeptides: MOC49_RS18290_sactipeptideNZ_JALANX010000001.1 Sactipeptides: MOC25_RS03365_sactipeptideNZ_JALAPT010000001.1 Sactipeptides: MOC95_RS01580_sactipeptideNZ_JALAPV010000005.1 Sactipeptides: MOC91_RS13515_sactipeptideNZ_JALAPW010000003.1 Sactipeptides: MOD18_RS06235_sactipeptideNZ_JALAPX010000003.1 Sactipeptides: MOC97_RS06805_sactipeptideNZ_JALAPZ010000002.1 Sactipeptides: MOC81_RS03830_sactipeptideNZ_JALAQA010000008.1 Sactipeptides: MOD07_RS14955_sactipeptideNZ_JALAQC010000001.1 Sactipeptides: MOD00_RS01290_sactipeptideNZ_JALAQD010000002.1 Sactipeptides: MOD08_RS05770_sactipeptideNZ_JALAQE010000002.1 Sactipeptides: MOD19_RS04725_sactipeptideNZ_JALASB010000002.1 Sactipeptides: MOD42_RS03685_sactipeptideNZ_JALASC010000024.1 Sactipeptides: MOD69_RS20580_sactipeptideNZ_JALASM010000006.1 Sactipeptides: MOD51_RS10970_sactipeptideNZ_JALASR010000006.1 Sactipeptides: MOD87_RS10780_sactipeptideNZ_JALAST010000011.1 Sactipeptides: MOE17_RS14670_sactipeptideNZ_JALASW010000005.1 Sactipeptides: MOE15_RS06925_sactipeptideNZ_JALATC010000001.1 Sactipeptides: MOD56_RS03380_sactipeptideNZ_JALATD010000001.1 Sactipeptides: MOE02_RS03350_sactipeptideNZ_JALATE010000006.1 Sactipeptides: MOD98_RS11440_sactipeptideNZ_JALATF010000003.1 Sactipeptides: MOD44_RS09960_sactipeptideNZ_JALATG010000002.1 Sactipeptides: MOE16_RS03490_sactipeptideNZ_JALATJ010000007.1 Sactipeptides: MOD90_RS15770_sactipeptideNZ_JALATU010000001.1 Sactipeptides: MOE27_RS01985_sactipeptideNZ_JALATV010000005.1 Sactipeptides: MOD97_RS07020_sactipeptideNZ_JALAUA010000008.1 Sactipeptides: MOD32_RS16030_sactipeptideNZ_JALAUD010000001.1 Sactipeptides: MOE28_RS03345_sactipeptideNZ_JALAUJ010000006.1 Sactipeptides: MOE37_RS12685_sactipeptideNZ_JALAUK010000012.1 Sactipeptides: MOE38_RS11825_sactipeptideNZ_JALAUV010000003.1 Sactipeptides: MOE71_RS06545_sactipeptideNZ_JALAUW010000015.1 Sactipeptides: MOE83_RS13210_sactipeptideNZ_JALAVA010000002.1 Sactipeptides: MOE81_RS02625_sactipeptideNZ_JALAVE010000001.1 Sactipeptides: MOE67_RS03645_sactipeptideNZ_JALAVI010000011.1 Sactipeptides: MOE80_RS14660_sactipeptideNZ_JALAVK010000006.1 Sactipeptides: MOE96_RS10120_sactipeptideNZ_JALAVL010000002.1 Sactipeptides: MOE60_RS03290_sactipeptideNZ_JALAVM010000009.1 Sactipeptides: MOE49_RS16195_sactipeptideNZ_JALAVO010000008.1 Sactipeptides: MOE63_RS14665_sactipeptideNZ_JALAVQ010000003.1 Sactipeptides: MOE59_RS02420_sactipeptideNZ_JALAVS010000002.1 Sactipeptides: MOE46_RS02250_sactipeptideNZ_JALAVT010000005.1 Sactipeptides: MOF25_RS08325_sactipeptideNZ_JALAVU010000004.1 Sactipeptides: MOE78_RS09660_sactipeptideNZ_JALAVV010000004.1 Sactipeptides: MOE66_RS02855_sactipeptideNZ_JALAVW010000001.1 Sactipeptides: MOE86_RS01005_sactipeptideNZ_JALAVX010000009.1 Sactipeptides: MOE40_RS07525_sactipeptideNZ_JALAVZ010000002.1 Sactipeptides: MOF00_RS02525_sactipeptideNZ_JALAWB010000008.1 Sactipeptides: MOE87_RS15020_sactipeptideNZ_JALAWK010000002.1 Sactipeptides: MOF06_RS12140_sactipeptideNZ_JALAWW010000010.1 Sactipeptides: MOF23_RS17300_sactipeptideNZ_JALAXQ010000012.1 Sactipeptides: MOF24_RS14120_sactipeptideNZ_JALAXV010000001.1 Sactipeptides: MOF15_RS00375_sactipeptideNZ_JALAYA010000016.1 Sactipeptides: MOF34_RS08915_sactipeptideNZ_JALAYD010000019.1 Sactipeptides: MOF39_RS20725_sactipeptideNZ_JALNTO010000006.1 Sactipeptides: MTN95_RS11045_sactipeptideNZ_JAMDFN010000008.1 Sactipeptides: M3M31_RS18245_sactipeptideNZ_JAMYDW010000003.1 Sactipeptides: NHM07_RS10830_sactipeptideNZ_JANBMP010000002.1 Sactipeptides: NL430_RS07940_sactipeptideNZ_JANDGG010000001.1 Sactipeptides: NKU38_RS03365_sactipeptideNZ_JANFAP010000001.1 Sactipeptides: NEC81_RS02065_sactipeptideNZ_JAQFFE010000015.1 Sactipeptides: PG051_RS13540_sactipeptideNZ_JAQOXM010000001.1 Sactipeptides: PO770_RS01950_sactipeptideNZ_JH600279.1 Sactipeptides: GYU_RS0104160_sactipeptideNZ_JXHL01000020.1 Sactipeptides: B4069_RS07025_sactipeptideNZ_JXHP01000031.1 Sactipeptides: B4073_RS09425_sactipeptideNZ_JXHR01000010.1 Sactipeptides: B4146_RS06925_sactipeptideNZ_KZ848487.1 Sactipeptides: DSL71_RS14015_sactipeptideNZ_LPVE01000021.1 Sactipeptides: AU385_RS06600_sactipeptideNZ_LSBB01000001.1 Sactipeptides: AXI57_RS01770_sactipeptideNZ_LUUT01000004.1 Sactipeptides: A6751_RS18460_sactipeptideNZ_MOEO01000004.1 Sactipeptides: BLL41_RS09830_sactipeptideNZ_MUXL01000002.1 Sactipeptides: B0W20_RS08845_sactipeptideNZ_MZZI01000001.1 Sactipeptides: B2G85_RS18515_sactipeptideNZ_NBBO01000003.1 Sactipeptides: B6K89_RS01830_sactipeptideNZ_NERK01000024.1 Sactipeptides: B9T64_RS18540_sactipeptideNZ_NJRD01000003.1 Sactipeptides: CE053_RS09115_sactipeptideNZ_NJRE01000002.1 Sactipeptides: CE047_RS07205_sactipeptideNZ_NKAK01000003.1 Sactipeptides: CE489_RS10400_sactipeptideNZ_NMOM01000004.1 Sactipeptides: CFI07_RS07245_sactipeptideNZ_PHIE01000002.1 Sactipeptides: CVV77_RS10760_sactipeptideNZ_PJCT01000002.1 Sactipeptides: CW370_RS11825_sactipeptideNZ_PVQM01000002.1 Sactipeptides: C6W22_RS11490_sactipeptideNZ_PVQN01000002.1 Sactipeptides: C6W23_RS05885_sactipeptideNZ_PVRK01000001.1 Sactipeptides: C6350_RS02025_sactipeptideNZ_PVWC01000004.1 Sactipeptides: C6372_RS11675_sactipeptideNZ_QRFZ01000012.1 Sactipeptides: DXT72_RS19010_sactipeptideNZ_SDKE01000003.1 Sactipeptides: EUA35_RS12130_sactipeptideNZ_SHOB01000002.1 Sactipeptides: ES060_RS14270_sactipeptideNZ_SIRN01000006.1 Sactipeptides: EYH65_RS15720_sactipeptideNZ_SNWK01000001.1 Sactipeptides: DFO69_RS02055_sactipeptideNZ_SOBO01000012.1 Sactipeptides: DFO78_RS18210_sactipeptideNZ_SORJ01000001.1 Sactipeptides: BJ795_RS03350_sactipeptideNZ_VBRP01000025.1 Sactipeptides: FE220_RS07065_sactipeptideNZ_VFNF01000001.1 Sactipeptides: FB592_RS03405_sactipeptideNZ_VIOH01000001.1 Sactipeptides: FLN47_RS01935_sactipeptideNZ_VLJK01000012.1 Sactipeptides: L605_RS10195_sactipeptideNZ_VLJL01000006.1 Sactipeptides: L604_RS05585_sactipeptideNZ_VLJX01000001.1 Sactipeptides: L609_RS01950_sactipeptideNZ_VTEK01000003.1 Sactipeptides: FZC71_RS10310_sactipeptideNZ_WTKJ01000004.1 Sactipeptides: NWT17_RS06185_sactipeptide

Sactipeptides: BSU_37350_sactipeptide

1

GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG

33

GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG

1

GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG

33

97.0% NZ_CP092751.1: Sactipeptides: MKF32_RS18515_sactipeptide

1

GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG

33

GCATCSIGA CLVDGPIPDFEIAGATGLFGLWG

1

GCATCSIGAVCLVDGPIPDFEIAGATGLFGLWG

33

93.9% NZ_CP048852.1: Sactipeptides: G4P54_RS19300_sactipeptide

1

GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG

33

GCATCSIGA CLVDGPIPDFE+AGATGLFGLWG

1

GCATCSIGAVCLVDGPIPDFEVAGATGLFGLWG

33

with 15 more sequence matches

90.9% NZ_JALAKO010000018.1and 1 other:

NZ_JALAOG010000035.1 Sactipeptides: MOC96_RS18415_sactipeptide

Sactipeptides: MOB26_RS11095_sactipeptide

1

GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG

33

GCATCSIGA CLVDGPIPDFEI G TGLFGLWG

1

GCATCSIGAVCLVDGPIPDFEIGGVTGLFGLWG

33

87.9% NZ_CP026362.1and 3 others:

NZ_CP033052.1 Sactipeptides: D9779_RS19215_sactipeptideNZ_JALAPG010000031.1 Sactipeptides: MOC70_RS13155_sactipeptideNZ_JALAQI010000016.1 Sactipeptides: MOD13_RS11485_sactipeptide

Sactipeptides: BV11031_RS20865_sactipeptide

1

GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG

33

GCATCSIGA CLVDG IPDFEI G TGLFGLWG

1

GCATCSIGAVCLVDGFIPDFEIGGVTGLFGLWG

33

78.8% NZ_NXEM01000021.1: Sactipeptides: CPT06_RS05595_sactipeptide

1

GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG

33

GC TCSIGA CLV+GPIPDF+ G TGLFGLWG

1

GCTTCSIGAVCLVNGPIPDFKTGGVTGLFGLWG

33

72.7% NC_014925.1and 17 others:

NZ_ANOI01000001.1 Sactipeptides: F779_RS13290_sactipeptideNZ_CP031604.1 Sactipeptides: DNJ55_RS07055_sactipeptideNZ_CP031605.1 Sactipeptides: DRC71_RS00165_sactipeptideNZ_CP035741.1 Sactipeptides: EW136_RS01865_sactipeptideNZ_CP039747.1 Sactipeptides: EFT29_RS00935_sactipeptideNZ_CP054206.2 Sactipeptides: HP560_RS11995_sactipeptideNZ_CP060700.1 Sactipeptides: H9Q12_RS10940_sactipeptideNZ_CP065920.1 Sactipeptides: JC281_RS11580_sactipeptideNZ_CP076465.1 Sactipeptides: KDE16_RS00560_sactipeptideNZ_JANPRJ010000013.1 Sactipeptides: NVR03_RS10250_sactipeptideNZ_JANPRN010000039.1 Sactipeptides: NVR04_RS07875_sactipeptideNZ_JTKO01000012.1 Sactipeptides: NO87_RS10650_sactipeptideNZ_LR134267.1 Sactipeptides: EL085_RS11430_sactipeptideNZ_MQMO01000006.1 Sactipeptides: BSR38_RS07375_sactipeptideNZ_MQNF01000024.1 Sactipeptides: BSR36_RS12515_sactipeptideNZ_QQPJ01000025.1 Sactipeptides: DV949_RS11300_sactipeptideNZ_SEZW01000001.1 Sactipeptides: EWV33_RS08610_sactipeptide

Sactipeptides: SPSINT_RS00615_sactipeptide

1

GCATCSIGAACLVDGPIPDFEIAGATGLFGL

31

GC+TCSIGAACL+DGP+PDFE+ G TG+FGL

1

GCSTCSIGAACLIDGPLPDFEVMGITGIFGL

31

69.7% NZ_CP027770.1: Sactipeptides: C7J90_RS04260_sactipeptide

1

GCATCSIGAACLVDGPIPDFEIAGATGLFGL

31

GC+ CSIGAACL+DGP PDFE+ G TG FGL

1

GCSACSIGAACLIDGPFPDFEVMGITGTFGL

31

69.7% NZ_CP066885.1: Sactipeptides: JGZ27_RS11325_sactipeptide

1

GCATCSIGAACLVDGPIPDFEIAGATGLFGL

31

GC+TCSIG ACL+DGP+PDFE+ G TG+FGL

1

GCSTCSIGVACLIDGPLPDFEVMGITGIFGL

31

69.7% NZ_CP094808.1and 3 others:

NZ_CP094809.1 Sactipeptides: MUA95_RS01320_sactipeptideNZ_CP094813.1 Sactipeptides: MUA84_RS01300_sactipeptideNZ_VKCY01000004.1 Sactipeptides: FNK43_RS05155_sactipeptide

Sactipeptides: MUA11_RS01375_sactipeptide

1

GCATCSIGAACLVDGPIPDFEIAGATGLFGL

31

GC+ C+IGAACL DGPIPDFE+AG TG FG+

1

GCSACAIGAACLADGPIPDFEVAGITGTFGI

31

66.7% NZ_ATDF02000020.1and 1 other:

NZ_KV827785.1 Sactipeptides: HMPREF2580_RS10900_sactipeptide

Sactipeptides: M462_RS08950_sactipeptide

1

GCATCSIGAACLVDGPIPDFEIAGATGLFGL

31

GC+ C++GAACL DGPIPDFE+AG TG FG+

1

GCSACAVGAACLADGPIPDFEVAGITGTFGM

31

63.6% NC_022584.1and 2 others:

NZ_CP047883.1 Sactipeptides: M594_RS05585_sactipeptideNZ_KV802690.1 Sactipeptides: HMPREF2764_RS03300_sactipeptide

Sactipeptides: N596_RS03165_sactipeptide

1

GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG

33

GC+ C+IGA CL DGPIPDFEIAG + +F +G

1

GCSVCAIGAVCLADGPIPDFEIAGVSAVFTAFG

33

63.6% NZ_CP063367.1and 1 other:

NZ_LR134263.1 Sactipeptides: EL101_RS12790_sactipeptide

Sactipeptides: IPU22_RS12430_sactipeptide

1

GCATCSIGAACLVDGPIPDFEIAGATGLFGL

31

GC+ C++GA CL DGPIPDFE+AG TG FG+

1

GCSACAVGAVCLADGPIPDFEVAGITGTFGI

31

60.6% NZ_LGRV01000006.1: Sactipeptides: AEA09_RS16245_sactipeptide

1

GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG

33

GC+ CSIGA CL+ GP+PDFE+A +G+F +WG

1

GCSACSIGAICLITGPVPDFEVASISGIFSVWG

33

54.5% NZ_CP066713.1: Sactipeptides: JGZ50_RS11620_sactipeptide

2

CATCSIGAACLVDGPIPDFEIAGATGLF

29

C+TCSIGAACL+DGP+PDF G F

1

CSTCSIGAACLIDGPLPDFRSHGNYWNF

28

42.4% NZ_PIZD01000012.1: Sactipeptides: allorf_25390_25524_sactipeptide

2

CATCSIGAACLVDGPIPDFEIAGATGLFGLW

32

C+ C++GA CL DGP PD E+ G + G +

3

CSFCAVGAGCLADGPFPDAEVVGVALIAGAF

33

18.2% NZ_CP016898.1: Lassopeptides: BEN76_RS17395_lassopeptide

14

DGPIPDFEIAGATGLF

29

GP+P++ + G G F

3

KGPLPEYFLMGGGGNF

18

17.1% NC_017030.1: Lanthipeptides: allorf_07530736_07530897_lanthipeptide

1

GCATCSIGAACLVDGPI

17

G +I C VDGP+

11

GVLRPAIARPCFVDGPV

27

Sactipeptides

Core peptide predictions

ctg2_388: Putative sactipeptide; RODEO score: 33.0; Core sequence, approximate: GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG

gnlProkkaCBIBJKBG_2 - Region 5 - CDPS

Download region GenBank file

Download region SVG

Location: 621,554 - 642,300 nt. (total: 20,747 nt) Show pHMM detection rules used

CDPS: (CDPS or cycdipepsynth)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

Gene overview

KnownClusterBlast

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

NRPS/PKS substrates

NRPS/PKS substrate predictions

gnlProkkaCBIBJKBG_2 - Region 6 - lanthipeptide-class-i

Download region GenBank file

Download region SVG

Location: 761,329 - 787,554 nt. (total: 26,226 nt) Show pHMM detection rules used

lanthipeptide-class-i: ((LANC_like and (Lant_dehydr_N or Lant_dehydr_C)) and not (YcaO or TIGR03604))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

KnownClusterBlast

Lanthipeptides

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

Lanthipeptide predictions

Lanthipeptide(s) for ctg2_759

ctg2_762

Leader:

MSKFDDFDLDVVKVSKQDSKITPQ

Core:

WKSESLCTPGCVTGVLQTCFLQTITCNCKISK

Core with dehydrations:

WKDhaEDhaLCysDhbPGCysVDhbGVLQDhbCysFLQDhbIDhbCysNCysKIDhaK

MIBiG 3.1 matches for ctg2_762

50.0% BGC0000535 (ADJ56352.1): Lanthipeptide: nisin A

3

SESLCTPGCVTGVLQTCFLQTITCNCKI

30

S SLCTPGC TG L C ++T TC+C I

3

SISLCTPGCKTGALMGCNMKTATCHCSI

30

antiSMASH-DB 4.0 matches for ctg2_762

100.0% NZ_CP021903.1and 20 others:

NZ_CP023409.1 Lanthipeptides: Bateq7PJ16_RS18530_lanthipeptideNZ_CP026036.1 Lanthipeptides: C2H93_RS15000_lanthipeptideNZ_CP028218.1 Lanthipeptides: C7M30_RS14555_lanthipeptideNZ_CP035167.1 Lanthipeptides: EQJ08_RS17140_lanthipeptideNZ_CP035226.1 Lanthipeptides: EQW70_RS18175_lanthipeptideNZ_CP045006.1 Lanthipeptides: F9B13_RS03875_lanthipeptideNZ_CP076083.1 Lanthipeptides: KFF76_RS16710_lanthipeptideNZ_CP079759.1 Lanthipeptides: KXZ66_RS17780_lanthipeptideNZ_CP080508.1 Lanthipeptides: K0V03_RS06525_lanthipeptideNZ_CP089148.1 Lanthipeptides: LRO88_RS19055_lanthipeptideNZ_JALAUA010000003.1 Lanthipeptides: MOD32_RS04985_lanthipeptideNZ_JALAVX010000009.1 Lanthipeptides: MOE40_RS09385_lanthipeptideNZ_JAMYDW010000007.1 Lanthipeptides: NHM07_RS16180_lanthipeptideNZ_JAQOXM010000001.1 Lanthipeptides: PO770_RS03875_lanthipeptideNZ_NJRD01000003.1 Lanthipeptides: CE053_RS07200_lanthipeptideNZ_NJRE01000008.1 Lanthipeptides: CE047_RS18435_lanthipeptideNZ_SORJ01000001.1 Lanthipeptides: BJ795_RS01490_lanthipeptideNZ_VFNF01000001.1 Lanthipeptides: FB592_RS01525_lanthipeptideNZ_VIOH01000001.1 Lanthipeptides: FLN47_RS03850_lanthipeptideNZ_VLJL01000012.1 Lanthipeptides: L604_RS09425_lanthipeptide

Lanthipeptides: CD007_RS17065_lanthipeptide

1

WKSESLCTPGCVTGVLQTCFLQTITCNCKISK

32

WKSESLCTPGCVTGVLQTCFLQTITCNCKISK

1

WKSESLCTPGCVTGVLQTCFLQTITCNCKISK

32

93.8% NC_014479.1and 9 others:

NZ_CP026362.1 Lanthipeptides: BV11031_RS00400_lanthipeptideNZ_CP033052.1 Lanthipeptides: D9779_RS17315_lanthipeptideNZ_CP051464.1 Lanthipeptides: HC660_RS17030_lanthipeptideNZ_JALAKK010000002.1 Lanthipeptides: MOB09_RS02800_lanthipeptideNZ_JALAKO010000014.1 Lanthipeptides: MOB26_RS08535_lanthipeptideNZ_JALAOG010000003.1 Lanthipeptides: MOC96_RS02500_lanthipeptideNZ_JALAPG010000043.1 Lanthipeptides: MOC70_RS16815_lanthipeptideNZ_JALAQI010000009.1 Lanthipeptides: MOD13_RS06065_lanthipeptideNZ_NXEM01000027.1 Lanthipeptides: CPT06_RS15285_lanthipeptide

Lanthipeptides: BSUW23_RS16845_lanthipeptide

1

WKSESLCTPGCVTGVLQTCFLQTITCNCKISK

32

WKSESLCTPGCVTG LQTCFLQT+TCNCKISK

1

WKSESLCTPGCVTGALQTCFLQTLTCNCKISK

32

93.8% NC_016047.1and 2 others:

NZ_KZ848487.1 Lanthipeptides: DSL71_RS15965_lanthipeptideNZ_MUXL01000003.1 Lanthipeptides: B0W20_RS12275_lanthipeptide

Lanthipeptides: GYO_RS39160_lanthipeptide

1

WKSESLCTPGCVTGVLQTCFLQTITCNCKISK

32

WKSES+CTPGCVTG+LQTCFLQTITCNCKISK

1

WKSESVCTPGCVTGLLQTCFLQTITCNCKISK

32

with 88 more sequence matches

93.8% NZ_CP025079.1and 3 others:

NZ_CP047644.1 Lanthipeptides: GNE05_RS17275_lanthipeptideNZ_CP099859.1 Lanthipeptides: NIZ95_RS16280_lanthipeptideNZ_CP101621.1 Lanthipeptides: NN913_RS16115_lanthipeptide

Lanthipeptides: BVQ_RS17705_lanthipeptide

1

WKSESLCTPGCVTGVLQTCFLQTITCNCKISK

32

WKSES+CTPGCVTGVLQTCFLQTITCNC ISK

1

WKSESVCTPGCVTGVLQTCFLQTITCNCHISK

32

84.4% NZ_BMMB01000002.1: Lanthipeptides: IEX62_RS05935_lanthipeptide

1

WKSESLCTPGCVTGVLQTCFLQTITCNCKISK

32

WKS+S CTPGCVTGVLQTCF+QT TCNC ISK

1

WKSKSFCTPGCVTGVLQTCFIQTATCNCHISK

32

84.4% NZ_CP117416.1and 1 other:

NZ_JAQQZQ010000001.1 Lanthipeptides: PO903_RS06885_lanthipeptide

Lanthipeptides: PQ456_RS01230_lanthipeptide

1

WKSESLCTPGCVTGVLQTCFLQTITCNCKISK

32

WKS+S CTPGCVTGVLQTCF+QT TCNC ISK

1

WKSQSFCTPGCVTGVLQTCFIQTATCNCHISK

32

62.5% NZ_AUAQ01000012.1: Lanthipeptides: G393_RS16160_lanthipeptide

1

WKSESLCTPGCVTGVLQTCFLQTITCNCKISK

32

WKS+SLCTPGC+TG+LQTC +Q+ TC +S+

1

WKSKSLCTPGCITGILQTCAIQSFTCEVHVSR

32

60.6% NZ_CP015405.2and 7 others:

NZ_CP015405.2 Lanthipeptides: A4V09_RS08295_lanthipeptideNZ_CP015405.2 Lanthipeptides: A4V09_RS08290_lanthipeptideNZ_CP015405.2 Lanthipeptides: A4V09_RS08285_lanthipeptideNZ_CP053228.1 Lanthipeptides: HL650_RS06240_lanthipeptideNZ_CP053228.1 Lanthipeptides: HL650_RS06235_lanthipeptideNZ_CP053228.1 Lanthipeptides: HL650_RS06230_lanthipeptideNZ_CP053228.1 Lanthipeptides: HL650_RS06225_lanthipeptide

Lanthipeptides: A4V09_RS08300_lanthipeptide

3

SESLCTPGCVTGVLQTCFLQTITCNCKIS

31

S+SLCTPGCVTG+L TC +QT TC C+I+

3

SKSLCTPGCVTGILMTCPVQTATCGCQIT

31

60.0% NZ_CP013655.1and 2 others:

NZ_CP013655.1 Lanthipeptides: ATZ35_RS03635_lanthipeptideNZ_CP013655.1 Lanthipeptides: ATZ35_RS03630_lanthipeptide

Lanthipeptides: ATZ35_RS03640_lanthipeptide

3

SESLCTPGCVTGVLQTCFLQTITCNCKIS

31

S+SLCTPGCVTGVL C L+TITCNC +

3

SKSLCTPGCVTGVLMGCALKTITCNCSVG

31

58.8% NZ_JADNFO010000025.1: Lanthipeptides: I2C89_RS09745_lanthipeptide

3

SESLCTPGCVTGVLQTCFLQTITCNCKI

30

S SLCTPGC TGVL C L+T TCNC I

3

SYSLCTPGCKTGVLMACHLKTATCNCSI

30

57.6% NZ_JADNJR010000016.1and 2 others:

NZ_JADNJR010000016.1 Lanthipeptides: I2E58_RS10875_lanthipeptideNZ_QSHK01000002.1 Lanthipeptides: DW860_RS04740_lanthipeptide

Lanthipeptides: I2E58_RS10880_lanthipeptide

1

WKSESLCTPGCVTGVLQTCFLQTITCNCKIS

31

+KS+S CTPGC TG+L TC L+T TC C I+

1

YKSKSACTPGCPTGILMTCPLKTATCGCHIT

31

57.6% NZ_QSHK01000002.1and 1 other:

NZ_QSHK01000002.1 Lanthipeptides: DW860_RS04730_lanthipeptide

Lanthipeptides: DW860_RS04735_lanthipeptide

1

WKSESLCTPGCVTGVLQTCFLQTITCNCKIS

31

+KS+S+CTPGC TG+L TC L+T TC C I+

1

YKSKSVCTPGCPTGILMTCPLKTATCGCHIT

31

54.3% NZ_FNDP01000013.1: Lanthipeptides: BLP54_RS11230_lanthipeptide

3

SESLCTPGCVTGVLQTCFLQTITCNCKI

30

S+SLCTPGCVTGVL C +T TCNC +

5

SKSLCTPGCVTGVLMGCNNKTATCNCSV

32

53.1% NC_015600.1and 14 others:

NZ_AP020310.1 Lanthipeptides: SAGCMC97051_RS07300_lanthipeptideNZ_ATVP01000001.1 Lanthipeptides: G574_RS11150_lanthipeptideNZ_BCFB01000042.1 Lanthipeptides: GOZ36_RS07980_lanthipeptideNZ_CP068708.1 Lanthipeptides: JM964_RS04040_lanthipeptideNZ_CP116958.1 Lanthipeptides: M0P28_RS07755_lanthipeptideNZ_CP116958.1 Lanthipeptides: M0P28_RS07755_lanthipeptideNZ_FIKS01000005.1 Lanthipeptides: A0525_RS10015_lanthipeptideNZ_GL636070.1 Lanthipeptides: HMPREF9171_RS106200_lanthipeptideNZ_JADPLU010000018.1 Lanthipeptides: I4V82_RS09545_lanthipeptideNZ_JAKVIE010000017.1 Lanthipeptides: MK857_RS08340_lanthipeptideNZ_JAQDQV010000001.1 Lanthipeptides: PGO74_RS00635_lanthipeptideNZ_JAQDQV010000001.1 Lanthipeptides: PGO74_RS00635_lanthipeptideNZ_LR594050.1 Lanthipeptides: FGL20_RS03485_lanthipeptideNZ_SSXN01000004.1 Lanthipeptides: FAJ36_RS04715_lanthipeptide

Lanthipeptides: SGPB_RS10680_lanthipeptide

3

SESLCTPGCVTGVLQTCFLQTITCNCKIS

31

S+SLCTPGC TG+L TC ++T TC C

3

SKSLCTPGCKTGILMTCAIKTATCGCHFG

31

53.1% NZ_AULX01000006.1and 1 other:

NZ_LT732548.1 Lanthipeptides: CZ379_RS19505_lanthipeptide

Lanthipeptides: H583_RS0100280_lanthipeptide

3

SESLCTPGCVTGVLQTCFLQTITCNCKISK

32

S+SLCTPGC+TGVL CF + C+IS

3

SKSLCTPGCITGVLM-CFTK----GCEISH

27

53.1% NZ_CP024974.1and 1 other:

NZ_JAIMDQ010000006.1 Lanthipeptides: K6V44_RS04045_lanthipeptide

Lanthipeptides: CVO91_RS06555_lanthipeptide

3

SESLCTPGCVTGVLQTCFLQTITCNCKI

30

S SLCTPGC TG+L TC ++T TC C

3

SISLCTPGCKTGILMTCAIKTATCGCHF

30

53.1% NZ_CP059471.1and 3 others:

NZ_FNZW01000001.1 Lanthipeptides: BMZ61_RS02110_lanthipeptideNZ_FOYC01000001.1 Lanthipeptides: BMZ88_RS03370_lanthipeptideNZ_KE384124.1 Lanthipeptides: G597_RS0106700_lanthipeptide

Lanthipeptides: H1R75_RS06635_lanthipeptide

3

SESLCTPGCVTGVLQTCFLQTITCNCKISK

32

S+SLCTPGC TG L TC ++T TC C

3

SKSLCTPGCKTGALMTCPIKTATCGCHFGN

32

53.1% NZ_JAMDIB010000004.1: Lanthipeptides: M5P35_RS04030_lanthipeptide

3

SESLCTP-GCVTGVLQTCFLQTITCNCKIS

31

S+SLCTP GC TG+L TC ++T TC C

3

SKSLCTPPGCKTGILMTCAIKTATCGCHFG

32

52.9% NC_013656.1and 20 others:

NC_020450.1 Lanthipeptides: LILO_RS03015_lanthipeptideNZ_CP009472.1 Lanthipeptides: LG36_RS03420_lanthipeptideNZ_CP010050.1 Lanthipeptides: QI18_RS03300_lanthipeptideNZ_CP015903.1 Lanthipeptides: LLUC08_RS03255_lanthipeptideNZ_CP024954.1 Lanthipeptides: CV702_RS02990_lanthipeptideNZ_CP066300.1 Lanthipeptides: LacL0098_RS03205_lanthipeptideNZ_CP098790.1 Lanthipeptides: M5C73_RS03405_lanthipeptideNZ_JAALEQ010000006.1 Lanthipeptides: HFD15_RS10120_lanthipeptideNZ_JAJONJ010000005.1 Lanthipeptides: LSG16_RS07195_lanthipeptideNZ_JAQDWM010000007.1 Lanthipeptides: PGU01_RS08180_lanthipeptideNZ_JAQDXV010000018.1 Lanthipeptides: PGT80_RS11850_lanthipeptideNZ_JAQDYA010000007.1 Lanthipeptides: PGT72_RS09560_lanthipeptideNZ_JAQDYA010000007.1 Lanthipeptides: PGT72_RS09560_lanthipeptideNZ_JAQEIZ010000019.1 Lanthipeptides: PGX18_RS12025_lanthipeptideNZ_JAQEOU010000022.1 Lanthipeptides: PGV42_RS12330_lanthipeptideNZ_JAQEOV010000015.1 Lanthipeptides: PGW09_RS10765_lanthipeptideNZ_MTJP01000006.1 Lanthipeptides: BW151_RS03795_lanthipeptideNZ_MTJR01000005.1 Lanthipeptides: BW153_RS02980_lanthipeptideNZ_MTJS01000002.1 Lanthipeptides: BW154_RS09850_lanthipeptideNZ_RAGL01000022.1 Lanthipeptides: D6108_RS11395_lanthipeptide

Lanthipeptides: LLKF_RS13210_lanthipeptide

3

SESLCTPGCVTGVLQTCFLQTITCNCKI

30

S SLCTPGC TG L C ++T TCNC I

3

SISLCTPGCKTGALMGCNMKTATCNCSI

30

51.5% NZ_FNDP01000013.1and 1 other:

NZ_FNDP01000013.1 Lanthipeptides: BLP54_RS11220_lanthipeptide

Lanthipeptides: BLP54_RS11225_lanthipeptide

3

SESLCTPGCVTGVLQTCFLQTITCNCKI

30

S+SLCTPGCVTG+L C + TCNC +

3

SKSLCTPGCVTGLLMGCAGSSATCNCSV

30

51.4% NZ_CP113114.1and 1 other:

NZ_FZDV01000015.1 Lanthipeptides: CFW84_RS08635_lanthipeptide

Lanthipeptides: OTU45_RS07045_lanthipeptide

3

SESLCTPGCVTGVLQTCFLQTITCN

27

S SLCTPGCVTGVL C TI+CN

3

SVSLCTPGCVTGVLM-CPGNTISCN

26

50.0% NC_022237.1and 1 other:

NZ_JUZI01000019.1 Lanthipeptides: ADI02_RS09325_lanthipeptide

Lanthipeptides: SII_RS05025_lanthipeptide

6

LCTPGCVTGVLQTCFLQTITCNCKI

30

+CTPGCVTG L C LQT TCNC +

6

MCTPGCVTGALMGCNLQTATCNCHV

30

50.0% NZ_CP009913.1and 1 other:

NZ_CP009913.1 Lanthipeptides: SSAL8618_RS00810_lanthipeptide

Lanthipeptides: SSAL8618_RS00815_lanthipeptide

3

SESLCTPGCVTGVLQTCFLQTITCNCKI

30

S SLCTPGC+TGVL C +Q+I CN +

3

SYSLCTPGCITGVLMGCHIQSIGCNVHV

30

50.0% NZ_CP065984.1and 2 others:

NZ_CP095737.1 Lanthipeptides: MXM90_RS03205_lanthipeptideNZ_JAQDXJ010000021.1 Lanthipeptides: PGU19_RS11740_lanthipeptide

Lanthipeptides: I6I21_RS02785_lanthipeptide

3

SESLCTPGCVTGVLQTCFLQTITCNCKI

30

S SLCTPGC TG L C ++T TC+C I

3

SISLCTPGCKTGALMGCNMKTATCHCSI

30

50.0% NZ_CP086322.1: Lanthipeptides: K9S39_RS23570_lanthipeptide

3

SESLCTPGCVTGVLQTCFLQTITCNCKISK

32

S SLCTPGCVT C T C ISK

3

SVSLCTPGCVTAA--GCTTAKCTQGCHISK

30

48.5% NC_009328.1and 6 others:

NZ_CP014140.1 Lanthipeptides: ACH33_RS18880_lanthipeptideNZ_CP014749.1 Lanthipeptides: A0V43_RS19510_lanthipeptideNZ_CP014749.1 Lanthipeptides: A0V43_RS19510_lanthipeptideNZ_CP017690.1 Lanthipeptides: GTID1_RS08690_lanthipeptideNZ_CP017694.1 Lanthipeptides: GD3902_RS07590_lanthipeptideNZ_PIJH01000004.1 Lanthipeptides: CV632_RS11810_lanthipeptide

Lanthipeptides: GTNG_RS18005_lanthipeptide

3

SESLCTPGCVTGVLQTCFLQT--ITCN

27

S+SLCTPGC+TGVL C Q ++CN

3

SKSLCTPGCITGVLM-CLTQNSCVSCN

28

47.1% NZ_JALGRO010000002.1: Lanthipeptides: MT346_RS01980_lanthipeptide

3

SESLCTPGCVTGVLQTCFLQTITCNCKISK

32

S SLCTPGC TG CF T C IS

3

SFSLCTPGCPTGGFA-CFTAACTGGCTISS

31

47.1% NZ_LR793265.1: Lanthipeptides: HV392_RS09830_lanthipeptide

3

SESLCTPGCVTGVLQTCFLQTITCNCKI

30

S SLCTPGC+TGVL C Q+ CN +

3

SYSLCTPGCITGVLMGCQFQSAGCNVHV

30

47.1% NZ_SNVW01000005.1: Lanthipeptides: EDF64_RS09155_lanthipeptide

3

SESLCTPGCVTGVLQTCFLQTITCNCKISK

32

S SLCTPGC TG CF T C IS

3

SVSLCTPGCPTGGFA-CFTAACTGGCTISS

31

46.9% NZ_CP025079.1and 2 others:

NZ_CP047644.1 Lanthipeptides: GNE05_RS17285_lanthipeptideNZ_CP099859.1 Lanthipeptides: NIZ95_RS16290_lanthipeptide

Lanthipeptides: BVQ_RS17715_lanthipeptide

3

SESLCTPGCVTGVLQTCFL

21

S+SLCTPGC+TG LQTC+L

3

SKSLCTPGCITGPLQTCYL

21

46.9% NZ_NDXL01000003.1: Lanthipeptides: B7024_RS31125_lanthipeptide

3

SESLCTPGCVTGVLQTCFLQTITCNCKISK

32

S SLCTPGCVT C T C +SK

3

SWSLCTPGCVTAA--GCTTSVCTQGCHVSK

30

45.7% NZ_JALDTZ010000003.1: Lanthipeptides: M1F37_RS03135_lanthipeptide

3

SESLCTPGCVTGVLQTCFLQTITCN

27

S S CTPGCVTG+L C TI+CN

3

SRSFCTPGCVTGILM-CPGNTISCN

26

45.5% NC_006510.1and 5 others:

NZ_CP018058.1 Lanthipeptides: GT3921_RS18655_lanthipeptideNZ_CP023704.1 Lanthipeptides: CQJ30_RS18315_lanthipeptideNZ_CP025074.1 Lanthipeptides: CWI35_RS08795_lanthipeptideNZ_CP027303.2 Lanthipeptides: C1N76_RS05790_lanthipeptideNZ_CP038860.1 Lanthipeptides: E5Z46_RS04660_lanthipeptide

Lanthipeptides: GK_RS18085_lanthipeptide

3

SESLCTPGCVTGVLQTCFLQT--ITCN

27

S+SLCTPGC+TG+L C Q ++CN

3

SKSLCTPGCITGILM-CLTQNSCVSCN

28

45.0% NZ_NHVL01000013.1and 1 other:

NZ_NHVL01000013.1 Lanthipeptides: CEU70_RS16825_lanthipeptide

Lanthipeptides: CEU70_RS16830_lanthipeptide

3

SESLCTPGCVTGVLQTCFLQTITCNCKI

30

S+SLCTPGC TG+LQTC +++ TC C I

5

SKSLCTPGCKTGILQTCAIKSATCGCSI

32

44.1% NZ_CP090412.1and 3 others:

NZ_QSTB01000004.1 Lanthipeptides: DXC22_RS03785_lanthipeptideNZ_VSTZ01000009.1 Lanthipeptides: FYK98_RS07445_lanthipeptideNZ_VSTZ01000009.1 Lanthipeptides: FYK98_RS07445_lanthipeptide

Lanthipeptides: LZF92_RS09890_lanthipeptide

3

SESLCTPGCVTGVLQTCFLQTITCNCKI

30

S SLCTPGC TG L C ++T +C C +

3

SYSLCTPGCKTGALMGCTMKTASCGCHV

30

44.1% NZ_FBTD01000003.1: Lanthipeptides: PB1E_RS03075_lanthipeptide

3

SESLCTPGCVTGVLQTCFLQTITCNCKI

30

S SLCTPGC TG L C ++T +C C +

3

SVSLCTPGCKTGALMGCNMKTASCGCHV

30

44.1% NZ_KE951497.1: Lanthipeptides: allorf_8519_8683_lanthipeptide

3

SESLCTPGCVTGVLQTCFLQTITCNCKIS

31

S+ LCTPGC TG + CF T C IS

3

SKFLCTPGCPTGGIA-CFTTQCTNGCSIS

30

44.1% NZ_LR793265.1: Lanthipeptides: HV392_RS09825_lanthipeptide

3

SESLCTPGCVTGVLQTCFLQTITCNCKI

30

S SLCTPGC+TG L C Q+ CN +

3

SYSLCTPGCITGRLMGCQFQSAGCNVHV

30

43.8% NZ_CP034587.1: Lanthipeptides: EKH77_RS16870_lanthipeptide

3

SESLCTPGCVTGVLQTCFLQTITCNCKISK

32

S SLCTPGC + C T C ISK

3

SISLCTPGCPSAA--GCTTSVCTQGCHISK

30

43.8% NZ_CP101621.1: Lanthipeptides: NN913_RS16125_lanthipeptide

3

SESLCTPGCVTGVLQTCFL

21

S+SLCTPGC+TG L+TC L

3

SKSLCTPGCITGALRTCTL

21

43.8% NZ_CP116604.1and 2 others:

NZ_JAFFHI010000008.1 Lanthipeptides: JN541_RS08535_lanthipeptideNZ_JAFFHJ010000004.1 Lanthipeptides: JN542_RS06245_lanthipeptide

Lanthipeptides: PHA78_RS04905_lanthipeptide

3

SESLCTPGCVTGVLQTCF-LQTITCNCK

29

S SLCT GC+TG + C T++CNC

3

SISLCTAGCITGRIMGCHKTPTVSCNCH

30

43.8% NZ_JAQEAZ010000004.1: Lanthipeptides: PGT18_RS05860_lanthipeptide

4

ESLCTPGCVTGVLQTCFLQT-ITCNCKI

30

S CTP C TG L C +T +TC CK+

4

HSFCTPNCPTGFL--CPPKTQLTCTCKL

29

42.4% NZ_CP085954.1: Lanthipeptides: LK411_RS13585_lanthipeptide

3

SESLCTPGCVTGVLQTCFLQ

22

S+SLCTPGC TG L CF Q

3

SKSLCTPGCPTGALG-CFTQ

21

41.2% NC_021022.1and 2 others:

NC_021022.1 Lanthipeptides: CK5_RS17320_lanthipeptideNZ_JADNJR010000016.1 Lanthipeptides: I2E58_RS10870_lanthipeptide

Lanthipeptides: CK5_RS17320_lanthipeptide

4

ESLCTPGCVTGVLQTCFLQT-ITCNCKI

30

S CTP C+TG L C +T +TC CK+

6

HSFCTPNCLTGFL--CPPKTQLTCTCKL

31

41.0% NZ_AP019008.1and 1 other:

NZ_BDDX01000012.1 Lanthipeptides: FF306_RS05510_lanthipeptide

Lanthipeptides: FF306_RS00060_lanthipeptide

3

SESLCTPGCVTGVLQTCFLQTITCNCKISK

32

S LCTPGC+TG L C +T TC+C S

3

SYVLCTPGCITGRLMGCNNKTKTCHCHSSN

32

41.0% NZ_JXCW01000008.1: Lanthipeptides: RZ55_RS07215_lanthipeptide

3

SESLCTPGCVTGVLQTCFLQTITCNCKISK

32

S LCTPGC+TG L C +T TC+C S

3

SYVLCTPGCITGRLMGCNNKTKTCHCHSSH

32

40.6% NZ_CP013655.1: Lanthipeptides: ATZ35_RS03625_lanthipeptide

3

SESLCTPGCVTGVLQTCFLQTITCN

27

S SLCT GC Q LQT+ CN

3

SVSLCTMGC-----QGSKLQTVICN

22

40.6% NZ_CP113914.1: Lanthipeptides: allorf_1411802_1411978_lanthipeptide

3

SESLCTPGCVTGVLQTCFLQTITCNCKIS

31

S SLCTPGC +G CF T C

3

SHSLCTPGCPSGGF-ACFSTQCTNGCHFG

30

40.6% NZ_FNDP01000013.1: Lanthipeptides: BLP54_RS11235_lanthipeptide

1

WKSESLCTPGCVTGVLQTC

19

+KS SLCTPGC TG+L C

1

FKSISLCTPGCPTGILMGC

19

40.6% NZ_WTWY01000020.1: Lanthipeptides: GQY55_RS27090_lanthipeptide

3

SESLCTPGCVTGVLQTCFLQTITCNCKIS

31

S +CTP C+TG L NCKIS

1

SGFICTPSCLTGTL----------NCKIS

19

37.5% NZ_JAIFIS010000001.1: Lanthipeptides: K1X09_RS26315_lanthipeptide

6

LCTPGCVTGVLQTCFLQTITCNCKIS

31

+CTP C+TG L NCKIS

4

ICTPSCLTGTL----------NCKIS

19

34.4% NZ_CP023477.1: Lanthipeptides: CO204_RS07210_lanthipeptide

1

WKSESLCTPGCV-TGVLQT

18

+KS SLCTPGC TG +

1

FKSWSLCTPGCARTGSFNS

19

31.2% NZ_CP015405.2and 1 other:

NZ_CP053228.1 Lanthipeptides: HL650_RS06245_lanthipeptide

Lanthipeptides: A4V09_RS08280_lanthipeptide

3

SESLCTPGCVTGVLQTC

19

S SLCT GC T TC

3

SISLCTSGCKTAFFGTC

19

31.2% NZ_GG667191.1and 1 other:

NZ_GG667191.1 Lanthipeptides: HMPREF0298_RS11685_lanthipeptide

Lanthipeptides: HMPREF0298_RS11685_lanthipeptide

3

SESLCTPGCVTG

14

S+SLCTPGC+TG

3

SKSLCTPGCITG

14

31.2% NZ_JHXK01000032.1and 1 other:

NZ_JHXK01000032.1 Lanthipeptides: T483_RS30515_lanthipeptide

Lanthipeptides: T483_RS30515_lanthipeptide

3

SESLCTPGCVTGVLQTCFLQT

23

S S CTPGC T + +TC ++

3

SYSACTPGCATSLFRTCLTRS

23

29.4% NZ_CABIWO010000014.1: Lanthipeptides: FY209_RS17155_lanthipeptide

3

SESLCTPGCVTGVL

16

S + CTPGCVTG L

2

SVAYCTPGCVTGQL

15

29.3% NZ_QOCT01000001.1: Lanthipeptides: DS833_RS00365_lanthipeptide

3

SESLCTPGCVTGVLQTC

19

S+SLCTPGC+TG L C

3

SKSLCTPGCITGRLMGC

19

28.1% NZ_CP013023.1: Lanthipeptides: allorf_0505345_0505512_lanthipeptide

2

KSESLCTPGC

11

KS+SLCTPGC

2

KSKSLCTPGC

11

28.1% NZ_CP033068.1: Lanthipeptides: EAG11_RS21865_lanthipeptide

11

CVTGVLQTCFLQTITCNCK

29

C TG +C T CNCK

3

CKTGSSSSCH-STAVCNCK

20

28.1% NZ_CP086149.1and 13 others:

NZ_CP086149.1 Lanthipeptides: LL127_RS22600_lanthipeptideNZ_CP086149.1 Lanthipeptides: LL127_RS22595_lanthipeptideNZ_CP086149.1 Lanthipeptides: LL127_RS22590_lanthipeptideNZ_CP086149.1 Lanthipeptides: LL127_RS22585_lanthipeptideNZ_CP086149.1 Lanthipeptides: LL127_RS22580_lanthipeptideNZ_CP086149.1 Lanthipeptides: LL127_RS22575_lanthipeptideNZ_CP086149.1 Lanthipeptides: LL127_RS22570_lanthipeptideNZ_CP087100.1 Lanthipeptides: LOR37_RS23225_lanthipeptideNZ_CP087100.1 Lanthipeptides: LOR37_RS23220_lanthipeptideNZ_CP087100.1 Lanthipeptides: LOR37_RS23215_lanthipeptideNZ_CP087100.1 Lanthipeptides: LOR37_RS23210_lanthipeptideNZ_CP087100.1 Lanthipeptides: LOR37_RS23205_lanthipeptideNZ_CP087100.1 Lanthipeptides: LOR37_RS23200_lanthipeptide

Lanthipeptides: LL127_RS22605_lanthipeptide

5

SLCTPGCVTGVLQTC

19

SLCT GC+TG + C

2

SLCTAGCITGRIMGC

16

25.7% NZ_CP075910.1and 3 others:

NZ_CP075971.1 Lanthipeptides: KLF29_RS14850_lanthipeptideNZ_CP075982.1 Lanthipeptides: KLF51_RS14900_lanthipeptideNZ_CP075994.1 Lanthipeptides: KLF26_RS16110_lanthipeptide

Lanthipeptides: KLF45_RS14835_lanthipeptide

3

SESLCTPGCVTGVL

16

S + CTPGC+TG L

3

SVAYCTPGCLTGEL

16

25.0% NC_003923.1and 11 others:

NC_009641.1 Lanthipeptides: NWMN_RS09635_lanthipeptideNZ_CP023076.1 Lanthipeptides: CJ017_RS08945_lanthipeptideNZ_CP047792.1 Lanthipeptides: E3S88_RS07345_lanthipeptideNZ_CP054876.1 Lanthipeptides: HUW54_RS09150_lanthipeptideNZ_CP077098.1 Lanthipeptides: KSF82_RS09475_lanthipeptideNZ_CP092781.1 Lanthipeptides: ML436_RS08940_lanthipeptideNZ_CP102959.1 Lanthipeptides: NW979_RS08780_lanthipeptideNZ_CP102962.1 Lanthipeptides: NW971_RS09555_lanthipeptideNZ_JAGSAY010000004.1 Lanthipeptides: KC186_RS06745_lanthipeptideNZ_LR133917.1 Lanthipeptides: ELZ45_RS09155_lanthipeptideNZ_LS483317.1 Lanthipeptides: DQL75_RS09700_lanthipeptide

Lanthipeptides: MW_RS09420_lanthipeptide

3

SESLCTPGCV

12

S SLCTPGC

4

SHSLCTPGCA

13

25.0% NC_014023.1and 43 others:

NC_014023.1 Lanthipeptides: BMQ_RS27575_lanthipeptideNZ_CP018875.1 Lanthipeptides: BUW91_RS26425_lanthipeptideNZ_CP018875.1 Lanthipeptides: BUW91_RS26420_lanthipeptideNZ_CP028091.1 Lanthipeptides: C1N54_RS28075_lanthipeptideNZ_CP028091.1 Lanthipeptides: C1N54_RS28070_lanthipeptideNZ_CP028091.1 Lanthipeptides: C1N54_RS28065_lanthipeptideNZ_CP031776.1 Lanthipeptides: D0441_RS30140_lanthipeptideNZ_CP041065.1 Lanthipeptides: FJM50_RS01185_lanthipeptideNZ_CP041065.1 Lanthipeptides: FJM50_RS01180_lanthipeptideNZ_CP041065.1 Lanthipeptides: FJM50_RS01175_lanthipeptideNZ_CP048884.1 Lanthipeptides: BMG_RS27510_lanthipeptideNZ_CP058263.1 Lanthipeptides: HW576_RS26980_lanthipeptideNZ_CP058263.1 Lanthipeptides: HW576_RS26975_lanthipeptideNZ_CP058263.1 Lanthipeptides: HW576_RS26970_lanthipeptideNZ_CP085427.1 Lanthipeptides: LIT30_RS26985_lanthipeptideNZ_CP085427.1 Lanthipeptides: LIT30_RS26980_lanthipeptideNZ_CP085427.1 Lanthipeptides: LIT30_RS26975_lanthipeptideNZ_CP085432.1 Lanthipeptides: LIT34_RS27820_lanthipeptideNZ_CP085432.1 Lanthipeptides: LIT34_RS27815_lanthipeptideNZ_CP085432.1 Lanthipeptides: LIT34_RS27810_lanthipeptideNZ_FNNQ01000006.1 Lanthipeptides: BLV90_RS07690_lanthipeptideNZ_FNNQ01000006.1 Lanthipeptides: BLV90_RS07685_lanthipeptideNZ_FNNQ01000006.1 Lanthipeptides: BLV90_RS07680_lanthipeptideNZ_FPAA01000016.1 Lanthipeptides: CHX35_RS16000_lanthipeptideNZ_FPAA01000016.1 Lanthipeptides: CHX35_RS15995_lanthipeptideNZ_FPAA01000016.1 Lanthipeptides: CHX35_RS15990_lanthipeptideNZ_FPAA01000016.1 Lanthipeptides: CHX35_RS15985_lanthipeptideNZ_JACJHT010000009.1 Lanthipeptides: HNP21_RS25635_lanthipeptideNZ_JACJHT010000009.1 Lanthipeptides: HNP21_RS25630_lanthipeptideNZ_JACJHT010000009.1 Lanthipeptides: HNP21_RS25625_lanthipeptideNZ_JAHHYI010000015.1 Lanthipeptides: KM925_RS26245_lanthipeptideNZ_JANIOE010000010.1 Lanthipeptides: NQ109_RS28075_lanthipeptideNZ_JANIOE010000010.1 Lanthipeptides: NQ109_RS28070_lanthipeptideNZ_JANIOE010000010.1 Lanthipeptides: NQ109_RS28065_lanthipeptideNZ_NKAQ01000005.1 Lanthipeptides: CE057_RS19640_lanthipeptideNZ_NKAQ01000005.1 Lanthipeptides: CE057_RS19635_lanthipeptideNZ_NTZG01000054.1 Lanthipeptides: CN510_RS18265_lanthipeptideNZ_NUIN01000020.1 Lanthipeptides: CN973_RS26930_lanthipeptideNZ_NUOI01000090.1 Lanthipeptides: COE08_RS30285_lanthipeptideNZ_NUOI01000090.1 Lanthipeptides: COE08_RS30280_lanthipeptideNZ_NUOQ01000009.1 Lanthipeptides: COE31_RS05925_lanthipeptideNZ_NUXL01000007.1 Lanthipeptides: COJ36_RS20885_lanthipeptideNZ_NUZS01000089.1 Lanthipeptides: COJ90_RS28785_lanthipeptide

Lanthipeptides: BMQ_RS27580_lanthipeptide

3

SESLCTPGC

11

S SLCTPGC

3

SVSLCTPGC

11

25.0% NZ_AP019791.1: Lanthipeptides: RxyAA322_RS06460_lanthipeptide

3

SESLCTPGCV

12

S SLCTPGC

3

SYSLCTPGCA

12

25.0% NZ_AP023356.1and 1 other:

NZ_FMZZ01000002.1 Lanthipeptides: BLS56_RS30480_lanthipeptide

Lanthipeptides: Aiant_RS23765_lanthipeptide

3

SESLCTPGCVT

13

S SLCTPGC +

3

SVSLCTPGCTS

13

25.0% NZ_AP025343.1: Lanthipeptides: allorf_1820803_1820973_lanthipeptide

2

KSESLCTPGC

11

S+SLCTPGC

2

DSKSLCTPGC

11

25.0% NZ_AXWW01000016.1and 2 others:

NZ_CP071248.1 Lanthipeptides: BLI009_RS04985_lanthipeptideNZ_JAMTCO010000009.1 Lanthipeptides: LV75_RS20160_lanthipeptide

Lanthipeptides: H504_RS39505_lanthipeptide

3

SESLCTPGCVT

13

S SLCTPGC +

3

SISLCTPGCTS

13

25.0% NZ_CP029370.1and 2 others:

NZ_JAFJXZ010000017.1 Lanthipeptides: JYU28_RS14110_lanthipeptideNZ_JAOYTP010000003.1 Lanthipeptides: OIU26_RS10605_lanthipeptide

Lanthipeptides: DI243_RS22305_lanthipeptide

10

GCVTGVLQTCFLQTITCNC

28

G VT + C+ +TCNC

4

GTVTCAVSACYDTYVTCNC

22

25.0% NZ_KI866523.1: Lanthipeptides: MPTA5024_RS39835_lanthipeptide

3

SESLCTPGCVT

13

S SLCTPGC +

3

SWSLCTPGCTS

13

25.0% NZ_QGTF01000010.1: Lanthipeptides: BDW27_RS18560_lanthipeptide

3

SESLCTPGCVTGVLQT

18

S S+CTPGC G +

3

SVSVCTPGCENGTFNS

18

25.0% NZ_QSHK01000002.1: Lanthipeptides: DW860_RS04745_lanthipeptide

3

SESLCTPGCVTGVLQ

17

S+SLCT C TG +

3

SKSLCTSSCETGFFK

17

25.0% NZ_VKCY01000012.1: Lanthipeptides: FNK43_RS09020_lanthipeptide

3

SESLCTPGCV

12

S SLCTPGC

5

SFSLCTPGCA

14

22.9% NZ_CP029639.1and 1 other:

NZ_QLLI01000019.1 Lanthipeptides: DET54_RS28075_lanthipeptide

Lanthipeptides: DMB88_RS07755_lanthipeptide

3

SESLCTPGCVTG

14

S + CTPGC TG

3

SVAYCTPGCNTG

14

22.9% NZ_CP034141.1: Lanthipeptides: EGM68_RS08790_lanthipeptide

1

WKSESLCTPGCVTG

14

+ S S CT GC+TG

1

YTSWSYCTTGCITG

14

22.9% NZ_CP070896.1and 2 others:

NZ_CP070896.1 Lanthipeptides: JWH23_RS09310_lanthipeptideNZ_CP070896.1 Lanthipeptides: JWH23_RS09310_lanthipeptide

Lanthipeptides: JWH23_RS09310_lanthipeptide

2

KSESLCTPGCVTG

14

S + CTPGC+TG

2

ASVAYCTPGCLTG

14

21.9% NC_006582.1and 6 others:

NZ_BOQQ01000001.1 Lanthipeptides: KI354_RS00530_lanthipeptideNZ_BOQS01000001.1 Lanthipeptides: KI364_RS00675_lanthipeptideNZ_CP019985.1 Lanthipeptides: BC8716_RS09795_lanthipeptideNZ_CP104963.1 Lanthipeptides: N7M99_RS07725_lanthipeptideNZ_FRBS01000002.1 Lanthipeptides: BUC05_RS08990_lanthipeptideNZ_JAODPB010000001.1 Lanthipeptides: N6H06_RS03040_lanthipeptide

Lanthipeptides: ABC_RS22115_lanthipeptide

1

WKSESLCTPGC

11

+ S S CTPGC

1

FTSVSFCTPGC

11

21.9% NC_014483.2and 30 others:

NC_014622.2 Lanthipeptides: PPSC2_RS36205_lanthipeptideNC_017542.1 Lanthipeptides: PPM_RS07465_lanthipeptideNC_023037.2 Lanthipeptides: X809_RS07820_lanthipeptideNZ_CP006872.1 Lanthipeptides: PPSQR21_RS07740_lanthipeptideNZ_CP017967.2 Lanthipeptides: PPYC1_RS07755_lanthipeptideNZ_CP017968.3 Lanthipeptides: PPYC2_RS08330_lanthipeptideNZ_CP023711.1 Lanthipeptides: CPY53_RS22235_lanthipeptideNZ_CP025957.1 Lanthipeptides: C1A50_RS07530_lanthipeptideNZ_CP029370.1 Lanthipeptides: DI243_RS07495_lanthipeptideNZ_CP040829.1 Lanthipeptides: FGY93_RS00500_lanthipeptideNZ_CP049598.1 Lanthipeptides: G7L40_RS00115_lanthipeptideNZ_CP061172.1 Lanthipeptides: IAQ67_RS07480_lanthipeptideNZ_CP073682.1 Lanthipeptides: KAI36_RS07745_lanthipeptideNZ_CP073683.1 Lanthipeptides: KAI37_RS07495_lanthipeptideNZ_CP084033.1 Lanthipeptides: LAZ93_RS07550_lanthipeptideNZ_CP085682.1 Lanthipeptides: LJR53_RS07370_lanthipeptideNZ_CP086373.1 Lanthipeptides: LMH85_RS07780_lanthipeptideNZ_CP092779.1 Lanthipeptides: MJ749_RS07440_lanthipeptideNZ_CP097766.1 Lanthipeptides: MF620_RS07485_lanthipeptideNZ_CP102865.1 Lanthipeptides: NWS42_RS21195_lanthipeptideNZ_CP109848.1 Lanthipeptides: OF859_RS22650_lanthipeptideNZ_CP113973.1 Lanthipeptides: OYT09_RS07785_lanthipeptideNZ_FOYG01000001.1 Lanthipeptides: BM358_RS03525_lanthipeptideNZ_JAAMNR010000001.1 Lanthipeptides: G9G54_RS03500_lanthipeptideNZ_JAKVDC010000001.1 Lanthipeptides: MKN04_RS02755_lanthipeptideNZ_JWJJ01000002.1 Lanthipeptides: U707_RS10390_lanthipeptideNZ_PNXQ01000013.1 Lanthipeptides: C1I60_RS14430_lanthipeptideNZ_POVS01000009.1 Lanthipeptides: C1T21_RS10630_lanthipeptideNZ_POVT01000009.1 Lanthipeptides: C1T20_RS05900_lanthipeptideNZ_PTJM01000020.1 Lanthipeptides: C5G87_RS02825_lanthipeptide

Lanthipeptides: PPE_RS07020_lanthipeptide

6

LCTPGCVTGVLQ

17

+CTP C TG L

4

ICTPSCATGTLN

15

21.9% NZ_CP020040.1: Lanthipeptides: allorf_294666_294851_lanthipeptide

2

KSESLCTPGCVTGVLQTC

19

+ E+ PG G LQ C

11

QGEAPLGPGGFEGSLQHC

28

21.9% NZ_CP094805.1: Lanthipeptides: MUA37_RS13310_lanthipeptide

3

SESLCTPGCV

12

S+ LCTPGC

3

SKFLCTPGCA

12

21.9% NZ_JADDUE010000020.1and 1 other:

NZ_LIVZ01000011.1 Lanthipeptides: AMK31_RS29125_lanthipeptide

Lanthipeptides: INP57_RS28495_lanthipeptide

3

SESLCTPGCVT

13

S S CTPGC +

3

SVSYCTPGCTS

13

21.9% NZ_LELK01000004.1: Lanthipeptides: AB986_RS12540_lanthipeptide

3

SESLCTPGC

11

S S CTPGC

3

SYSFCTPGC

11

21.9% NZ_NIST01000001.1: Lanthipeptides: CD001_RS09870_lanthipeptide

5

SLCTPGCVTGVLQ

17

+CTP C+TG L

3

GICTPSCLTGTLN

15

20.0% NZ_CP073683.1and 1 other:

NZ_CP092779.1 Lanthipeptides: MJ749_RS08075_lanthipeptide

Lanthipeptides: KAI37_RS08180_lanthipeptide

7

CTPGCVTG

14

CTPGC+TG

7

CTPGCITG

14

18.8% NZ_CP029370.1: Lanthipeptides: DI243_RS07485_lanthipeptide

6

LCTPGCVTGVLQ

17

+CTP C+T +L

4

ICTPTCLTSILN

15

18.8% NZ_CP059572.1: Lanthipeptides: AGRA3207_RS17530_lanthipeptide

3

SESLCTPGCVT

13

S ++CTPGC +

3

SHAVCTPGCTS

13

18.8% NZ_CP090942.1: Lanthipeptides: LZT96_RS12010_lanthipeptide

3

SESLCTPGCV

12

S+ +CTPGC

3

SKFICTPGCA

12

18.8% NZ_CP096658.1: Lanthipeptides: allorf_3178073_3178228_lanthipeptide

4

ESLCTPGCVTGV

15

ES C+P C T

3

ESYCSPKCQTAA

14

18.8% NZ_FNNQ01000013.1: Lanthipeptides: BLV90_RS16000_lanthipeptide

6

LCTPGCVTGVLQT

18

+CTPGC G ++

2

ICTPGCDEGTFES

14

18.8% NZ_ML974127.1: Lanthipeptides: allorf_1546009_1546125_lanthipeptide

3

SESLCTPGCVTGV

15

ES C+P C T

1

DESYCSPKCQTAA

13

14.3% NZ_QJTF01000024.1: Lanthipeptides: allorf_35736_35903_lanthipeptide

3

SESLCTPGCVTG

14

+ +LC+ GC TG

11

NNALCSDGCSTG

22

13.5% NZ_FWXM01000003.1: Lanthipeptides: B8967_RS11230_lanthipeptide

7

CTPGCVTGVLQTCFLQTITCNC

28

C+ GC++ + T L NC

24

CSDGCLSNFMHTHVLNCSKANC

45

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Lanthipeptides

Core peptide predictions

ctg2_762 - Class I

Cleavage pHMM score: 27.80

RODEO score: 29

Monoisotopic mass: 3346.7 Da

Molecular weight: 3349.0 Da

Number of bridges: 5

Alternative weights: (assuming N unmodified Ser/Thr residues); 3367.0 Da N = 1; 3385.0 Da N = 2; 3403.0 Da N = 3

gnlProkkaCBIBJKBG_2 - Region 7 - NRP-metallophore,NRPS

Download region GenBank file

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Location: 933,784 - 985,561 nt. (total: 51,778 nt) Show pHMM detection rules used

NRP-metallophore: (VibH_like or Cy_tandem or (cds(Condensation and AMP-binding) and ((IBH_Asp and not SBH_Asp) or IBH_His or TBH_Asp or CyanoBH_Asp1 or CyanoBH_Asp2 or IPL or SalSyn or (EntA and EntC) or (GrbD and GrbE) or (FbnL and FbnM) or PvdO or PvdP or (Orn_monoox and not (KtzT or MetRS-like)) or Lys_monoox or VbsL)))
NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

Gene overview

NRPS/PKS domains

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters from MIBiG 3.1

Module view

Legend

NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 7, location 933783 - 985561:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Gly - Thr)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg2_949

Search NORINE for peptide: strict or relaxed

AMP-binding (31..435): diOH-Bz

nrpys: diOH-Bz

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic (Phe, Tyr, diOH-Bz, Ph-Gly, bOH-Tyr)
Large clusters prediction:: Hydroxy-benzoic acid derivates (diOH-Bz, Sal)
Small clusters prediction:: Hydroxy-benzoic acid derivates (diOH-Bz, Sal)
Single AA prediction:: dhb (diOH-Bz)

Stachelhaus prediction details:

Stachelhaus sequence:: PLPAQGVVNK
Nearest Stachelhaus code(s):: diOH-Bz PLPAQGVVNK (100% 8Å match); diOH-Bz or Sal PLPAQGVVNK (94% 8Å match)
Stachelhaus code match:: 100% (strong)

ctg2_951

Search NORINE for peptide: strict or relaxed

AMP-binding (463..861): Gly

nrpys: Gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Tiny, hydrophilic, transition to aliphatic (Gly, Ala)
Single AA prediction:: gly (Gly)

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGLIWK
Nearest Stachelhaus code(s):: Gly DILQLGLIWK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (1519..1935): Thr

nrpys: Thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Aliphatic chain or phenyl group with -OH (Ser, Thr, Dhpg, Hpg)
Small clusters prediction:: thr (Thr)
Single AA prediction:: thr (Thr)

Stachelhaus prediction details:

Stachelhaus sequence:: DFWNIGMVHK
Nearest Stachelhaus code(s):: Thr DFWNIGMVHK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

gnlProkkaCBIBJKBG_3 - Region 1 - NRPS,betalactone

Download region GenBank file

Download region SVG

Location: 1 - 38,546 nt. (total: 38,546 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))
betalactone: (HMGL-like and AMP-binding)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

Gene overview

NRPS/PKS domains

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters from MIBiG 3.1

Module view

Legend

NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 38546:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-Val) + (Pro - Glu - D-Tyr) + (Ile)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg3_1

Search NORINE for peptide: strict or relaxed

AMP-binding (240..633): Val

nrpys: Val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: val (Val)

Stachelhaus prediction details:

Stachelhaus sequence:: DVFWIGGTFK
Nearest Stachelhaus code(s):: Val DVFWIGGTFK (100% 8Å match); Ala or Val DVFWIGGTFK (91% 8Å match)
Stachelhaus code match:: 100% (strong)

ctg3_2

Search NORINE for peptide: strict or relaxed

AMP-binding (469..866): Pro

nrpys: Pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Cyclic aliphatic chain (polar NH2 group) (Pro, Hpr)
Small clusters prediction:: pro (Pro)
Single AA prediction:: pro (Pro)

Stachelhaus prediction details:

Stachelhaus sequence:: DVQFIAHVVK
Nearest Stachelhaus code(s):: Pro DVQFIAHVVK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (1500..1901): Glu

nrpys: Glu

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: glu,gln (Glu, Gln)
Single AA prediction:: glu (Glu)

Stachelhaus prediction details:

Stachelhaus sequence:: DAWHFGSVEK
Nearest Stachelhaus code(s):: Glu DAWHFGSVEK (100% 8Å match); Gln DAWHFGSVEK (94% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (2539..2933): Tyr

nrpys: Tyr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic (Phe, Tyr, diOH-Bz, Ph-Gly, bOH-Tyr)
Large clusters prediction:: Aromatic side chain (Phe, Trp, Ph-Gly, Tyr, bOH-Tyr)
Small clusters prediction:: Polar aromatic ring (Tyr, bOH-Tyr)
Single AA prediction:: tyr (Tyr)

Stachelhaus prediction details:

Stachelhaus sequence:: DGTITAEVAK
Nearest Stachelhaus code(s):: Tyr DGTITAEVAK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

ctg3_3

Search NORINE for peptide: strict or relaxed

AMP-binding (474..867): Ile

nrpys: Ile

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: ile (Ile)

Stachelhaus prediction details:

Stachelhaus sequence:: DAFFYGITFK
Nearest Stachelhaus code(s):: Ile DAFFYGITFK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

ctg3_7

AMP-binding (13..445): X

nrpys: Asp, Asn, Glu, Gln, Aad

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: -GLHIAAPVK
Nearest Stachelhaus code(s):: Z-ahmohOrn FGLHIASTCK (56% 8Å match); Ile DGLFIGIPVK (32% 8Å match)
Stachelhaus code match:: 60% (weak)

gnlProkkaCBIBJKBG_3 - Region 2 - NRPS,PKS-like,T3PKS,transAT-PKS

Download region GenBank file

Download region SVG

Location: 100,968 - 215,753 nt. (total: 114,786 nt) Show pHMM detection rules used

transAT-PKS: (cds(PKS_AT and not (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) and (cds(ATd and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) or cds(tra_KS and PP-binding)))
NRPS: cds(Condensation and (AMP-binding or A-OX))
T3PKS: cds(Condensation and (AMP-binding or A-OX))
PKS-like: (Chal_sti_synt_C or Chal_sti_synt_N)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

NRPS/PKS domains

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters from MIBiG 3.1

Module view

Legend

NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 2, location 100967 - 215753:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Gly - ccmal - ohmal - mal) + (ccmal - mal - ohmal - mal) + (Me-ccmal - ohmal - mal) + (Ala - ccmal - ccmal - Me-ccmal) + (mal - mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg3_120

Search NORINE for peptide: strict or relaxed

AMP-binding (497..905): Ala

nrpys: Ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVSNMAIIYK
Nearest Stachelhaus code(s):: Ala DVSNMAIIYK (91% 8Å match)
Stachelhaus code match:: 100% (strong)

ctg3_123

Search NORINE for peptide: strict or relaxed

CAL_domain (60..476): pk

minowa: fatty_acid

Prediction, score:

fatty_acid: 14.2
NH2: 10.3
shikimic_acid: 0.0
Acetyl-CoA: 0.0
AHBA: 0.0

AMP-binding (1159..1554): Gly

nrpys: Gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Tiny, hydrophilic, transition to aliphatic (Gly, Ala)
Single AA prediction:: gly (Gly)

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGMIWK
Nearest Stachelhaus code(s):: Gly DILQLGMIWK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

ctg3_129

PKS_AT (4..288): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 87.5%; inactive: 66.7%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 95.0
inactive: 41.2
Methoxymalonyl-CoA: 29.1
Methylmalonyl-CoA: 22.1
Propionyl-CoA: 16.3
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ctg3_130

PKS_AT (7..293): pk

ATSignature: (unknown)

No matches above 50%

minowa: inactive

Prediction, score:

inactive: 30.0
Malonyl-CoA: 23.0
Benzoyl-CoA: 8.8
Isobutyryl-CoA: 8.4
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Methylmalonyl-CoA: 0.0
Methoxymalonyl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ctg3_132

PKS_AT (4..284): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 87.5%; inactive: 62.5%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 96.7
Methoxymalonyl-CoA: 50.0
inactive: 35.3
Methylmalonyl-CoA: 31.5
Propionyl-CoA: 22.2
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

gnlProkkaCBIBJKBG_3 - Region 3 - lanthipeptide-class-i

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Location: 237,980 - 264,275 nt. (total: 26,296 nt) Show pHMM detection rules used

lanthipeptide-class-i: ((LANC_like and (Lant_dehydr_N or Lant_dehydr_C)) and not (YcaO or TIGR03604))

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Similar known gene clusters from MIBiG 3.1

No matches found.

Lanthipeptide predictions

Lanthipeptide(s) for ctg3_184

ctg3_185

Leader:

MEKDIFDLDLKIQTSKSNVEPN

Core:

SIRLTFGCSGGVASKALCSRAMCDGIVITKNYGYCDA

Core with dehydrations:

DhaIRLDhbFGCysDhaGGVADhaKALCysDhaRAMCysDGIVIDhbKNYGYCysDA

MIBiG 3.1 matches for ctg3_185

10.8% BGC0000503 (cinA): Lanthipeptide: cinnamycin

4

LTFGCSGGV

12

TF C G

10

FTFVCDGNT

18

10.8% BGC0000535 (ADJ56352.1): Lanthipeptide: nisin A

5

TFGCSGG

11

T GC G

8

TPGCKTG

14

antiSMASH-DB 4.0 matches for ctg3_185

100.0% NZ_CP021903.1and 6 others:

NZ_CP023409.1 Lanthipeptides: Bateq7PJ16_RS09270_lanthipeptideNZ_CP028218.1 Lanthipeptides: C7M30_RS01850_lanthipeptideNZ_CP035167.1 Lanthipeptides: EQJ08_RS08875_lanthipeptideNZ_CP089148.1 Lanthipeptides: LRO88_RS09410_lanthipeptideNZ_JAMYDW010000001.1 Lanthipeptides: NHM07_RS00470_lanthipeptideNZ_JAQOXM010000003.1 Lanthipeptides: PO770_RS15540_lanthipeptide

Lanthipeptides: CD007_RS08815_lanthipeptide

1

SIRLTFGCSGGVASKALCSRAMCDGIVITKNYGYCDA

37

SIRLTFGCSGGVASKALCSRAMCDGIVITKNYGYCDA

1

SIRLTFGCSGGVASKALCSRAMCDGIVITKNYGYCDA

37

94.6% NZ_JAJQVT010000008.1: Lanthipeptides: PAF28_RS14660_lanthipeptide

1

SIRLTFGCSGGVASKALCSRAMCDGIVITKNYGYCDA

37

SIRLTFGC+GGVASKALCSRAMCDGIVITKNYGYC+A

1

SIRLTFGCTGGVASKALCSRAMCDGIVITKNYGYCEA

37

24.3% NZ_JAASAG010000001.1: Lanthipeptides: allorf_344422_344553_lanthipeptide

9

SGGVASKALCSRAMCDGI

26

+GG KA C RA C I

1

AGGPVRKAGCQRAGCKRI

18

with 5 more sequence matches

21.6% NZ_KZ857173.1: Lanthipeptides: allorf_741535_741753_lanthipeptide

1

SIRLTFGCSGGVA

13

IRLT GCS G++

11

QIRLTTGCSTGLS

23

16.2% NZ_PVRU01000017.1and 3 others:

NZ_PVRU01000017.1 Lanthipeptides: C6360_RS28255_lanthipeptideNZ_PVRU01000017.1 Lanthipeptides: C6360_RS28260_lanthipeptideNZ_PVRU01000017.1 Lanthipeptides: C6360_RS28255_lanthipeptide

Lanthipeptides: C6360_RS28260_lanthipeptide

12

VASKALCSRAMCDGIVITKNY

32

+ S LC+ + I ++K+Y

14

ITSTVLCANGLTISIAVSKSY

34

13.5% NZ_BNCE01000001.1: Lanthipeptides: IE320_RS02935_lanthipeptide

10

GGVASKALCSRAMCD

24

G+A++ +C+R C

3

SGIATRTICTRVTCQ

17

13.3% NZ_CP009280.1and 1 other:

NZ_CP009280.1 Lanthipeptides: allorf_0384816_0385007_lanthipeptide

Lanthipeptides: allorf_0384816_0385007_lanthipeptide

22

MCDGIVITKNYG

33

+CD I+ NYG

33

VCDKILFPHNYG

44

11.6% NZ_JALGBX010000020.1and 1 other:

NZ_JANAVF010000016.1 Lanthipeptides: NLX94_RS30150_lanthipeptide

Lanthipeptides: MTF69_RS28785_lanthipeptide

11

GVASKALCSRAMCDG

25

G+A++ +C+R C

11

GIATRTVCTRVTCQA

25

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Lanthipeptides

Core peptide predictions

ctg3_185 - Class I

Cleavage pHMM score: 13.90

RODEO score: 23

Monoisotopic mass: 3721.8 Da

Molecular weight: 3724.3 Da

Number of bridges: 4

Alternative weights: (assuming N unmodified Ser/Thr residues); 3742.3 Da N = 1; 3760.4 Da N = 2

gnlProkkaCBIBJKBG_3 - Region 4 - terpene

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Location: 815,842 - 836,645 nt. (total: 20,804 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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No matches found.

gnlProkkaCBIBJKBG_5 - Region 1 - NRPS

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Location: 1 - 26,815 nt. (total: 26,815 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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Detailed domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 26815:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-Leu) + (Leu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg5_1

Search NORINE for peptide: strict or relaxed

AMP-binding (1..333): Leu

nrpys: Leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: leu (Leu)

Stachelhaus prediction details:

Stachelhaus sequence:: DAWFLGNVVK
Nearest Stachelhaus code(s):: Leu DAWFLGNVVK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

ctg5_2

Search NORINE for peptide: strict or relaxed

AMP-binding (469..867): Leu

nrpys: Leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: leu (Leu)

Stachelhaus prediction details:

Stachelhaus sequence:: DAFFLGCVFK
Nearest Stachelhaus code(s):: Leu DAFFLGCVFK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

gnlProkkaCBIBJKBG_6 - Region 1 - NRPS

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Location: 172,783 - 200,433 nt. (total: 27,651 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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		NT	AA		NT	AA

Detailed domain annotation

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 172782 - 200433:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Glu - Leu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg6_182

Search NORINE for peptide: strict or relaxed

AMP-binding (466..867): Glu

nrpys: Glu

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: glu,gln (Glu, Gln)
Single AA prediction:: gln (Gln)

Stachelhaus prediction details:

Stachelhaus sequence:: DAKDLGVVDK
Nearest Stachelhaus code(s):: Glu DAKDLGVVDK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (1510..1908): Leu

nrpys: Leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: leu (Leu)

Stachelhaus prediction details:

Stachelhaus sequence:: DAFMMGMVFK
Nearest Stachelhaus code(s):: Leu DAFMMGMVFK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

gnlProkkaCBIBJKBG_10 - Region 1 - NRPS

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Location: 1 - 14,176 nt. (total: 14,176 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 14176:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-Orn) + (Tyr - D-Thr)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg10_1

Search NORINE for peptide: strict or relaxed

AMP-binding (469..870): Glu

nrpys: Glu

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: glu,gln (Glu, Gln)
Single AA prediction:: glu (Glu)

Stachelhaus prediction details:

Stachelhaus sequence:: DAWHFGGIDK
Nearest Stachelhaus code(s):: Glu DAWHFGGVDK (97% 8Å match)
Stachelhaus code match:: 90% (moderate)

ctg10_2

Search NORINE for peptide: strict or relaxed

AMP-binding (474..865): Tyr

nrpys: Tyr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic (Phe, Tyr, diOH-Bz, Ph-Gly, bOH-Tyr)
Large clusters prediction:: Aromatic side chain (Phe, Trp, Ph-Gly, Tyr, bOH-Tyr)
Small clusters prediction:: Polar aromatic ring (Tyr, bOH-Tyr)
Single AA prediction:: tyr (Tyr)

Stachelhaus prediction details:

Stachelhaus sequence:: DGTITAEVAK
Nearest Stachelhaus code(s):: Tyr DGTITAEVAK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (1505..1903): Thr

nrpys: Thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Aliphatic chain or phenyl group with -OH (Ser, Thr, Dhpg, Hpg)
Small clusters prediction:: thr (Thr)
Single AA prediction:: thr (Thr)

Stachelhaus prediction details:

Stachelhaus sequence:: DFWNIGMVHK
Nearest Stachelhaus code(s):: Thr DFWNIGMVHK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

ctg10_3

Search NORINE for peptide: strict or relaxed

AMP-binding (176..581): Orn

nrpys: Orn

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Long positively charged side chain (Orn, Lys, Arg)
Small clusters prediction:: Orn and hydroxy-Orn specific (Orn, OH-Orn)
Single AA prediction:: orn (Orn)

Stachelhaus prediction details:

Stachelhaus sequence:: DVGEIGSIDK
Nearest Stachelhaus code(s):: Orn DVGEIGSIDK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

gnlProkkaCBIBJKBG_11 - Region 1 - NRPS

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Location: 1 - 9,243 nt. (total: 9,243 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 9243:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Val - Asp)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg11_1

Search NORINE for peptide: strict or relaxed

AMP-binding (470..864): Val

nrpys: Val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: val (Val)

Stachelhaus prediction details:

Stachelhaus sequence:: DAFWIGGTFK
Nearest Stachelhaus code(s):: Val DAFWIGGTFK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (1501..1904): Asp

nrpys: Asp

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: asp,asn (Asp, Asn)
Single AA prediction:: asp (Asp)

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKVGHIGK
Nearest Stachelhaus code(s):: Asp DLTKVGHIGK (100% 8Å match)
Stachelhaus code match:: 100% (strong)