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Overview
1.1
1.2
1.3
1.4
1.5
1.6

### Identified secondary metabolite regions using strictness 'relaxed'

gnlProkkaCJPBALEN_1 (original name was: gnl|Prokka|CJPBALEN_1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1 | lanthipeptide-class-v | 161,955 | 203,819 |
Region 2 | NRPS-like | 340,966 | 384,085 |
Region 3 | lanthipeptide-class-ii | 629,962 | 652,475 | thermophilin 1277 | RiPP:Lanthipeptide | 80%
Region 4 | RiPP-like | 878,276 | 896,043 | ubericin K | Other | 12%
Region 5 | RaS-RiPP | 1,238,905 | 1,261,329 | streptide | RiPP | 100%
Region 6 | RiPP-like | 1,522,462 | 1,550,873 |

gnlProkkaCJPBALEN_1 - Region 1 - lanthipeptide-class-v
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 161,955 - 203,819 nt. (total: 41,865 nt) Show pHMM detection rules used
lanthipeptide-class-v: (APH and HopA1)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
KnownClusterBlast
Lanthipeptides
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Lanthipeptide predictions
Shows the possible core peptides for each biosynthetic enzyme.
Includes CompaRiPPson results for any available databases, with a detailed explanation here.
Lanthipeptides - No core peptides found.
Lanthipeptides
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists the number of lanthionine bridges, possible molecular weights, and the scores for cleavage site prediction and RODEO.
No core peptides found.
gnlProkkaCJPBALEN_1 - Region 2 - NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 340,966 - 384,085 nt. (total: 43,120 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
NRPS/PKS domains
KnownClusterBlast
NRPS/PKS modules
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A domain glossary is available here, and an explanation of the visualisation is available here.
Selected features only
Show module domains
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Module view
Shows module structures for each candidate cluster in NRPS and PKS regions.
Genes are shown in predicted order, and are only present when containing at least one complete module.
A domain glossary is available here, and an explanation of the visualisation is available here.
Legend
NRPS/PKS products
NRPS/PKS substrates
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 2, location 340965 - 384085:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (X)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS substrate predictions
Shows the predicted substrates for each adenylation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg1_376: mal
  PKS_AT (7..281): mal
  ATSignature: Malonyl-CoA
  Top 3 matches:
    Malonyl-CoA: 62.5%
  minowa: Malonyl-CoA
  Prediction, score:
    Malonyl-CoA: 30.6
    Methoxymalonyl-CoA: 25.5
    Methylmalonyl-CoA: 17.4
    inactive: 13.4
    trans-1,2-CPDA: 0.0
    fatty_acid: 0.0
    Propionyl-CoA: 0.0
    Isobutyryl-CoA: 0.0
    Ethylmalonyl-CoA: 0.0
    CHC-CoA: 0.0
    Benzoyl-CoA: 0.0
    Acetyl-CoA: 0.0
    3-Methylbutyryl-CoA: 0.0
    2-Methylbutyryl-CoA: 0.0
ctg1_377: X
  AMP-binding (31..257): X
  nrpys: (unknown)
  SVM prediction details:
    NOTE: uncertain match
    Predicted physicochemical class:
      hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
    Large clusters prediction:
      Polar, uncharged (aliphatic with -SH) (Cys)
    Small clusters prediction:
      Polar, uncharged (aliphatic with -SH) (Cys)
    Single AA prediction:
      Polar, uncharged (aliphatic with -SH) (Cys)
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DLFN-----K
    Nearest Stachelhaus code(s):
    Stachelhaus code match:
      0% (weak)

gnlProkkaCJPBALEN_1 - Region 3 - lanthipeptide-class-ii
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 629,962 - 652,475 nt. (total: 22,514 nt) Show pHMM detection rules used
lanthipeptide-class-ii: cds(LANC_like and DUF4135)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
KnownClusterBlast
Lanthipeptides
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Lanthipeptide predictions
Shows the possible core peptides for each biosynthetic enzyme.
Includes CompaRiPPson results for any available databases, with a detailed explanation here.

#### Lanthipeptide(s) for ctg1_655

ctg1_654
Leader:
MMNATENQIFVETVSDQELEMLIGG
Core:
A D R G W I K T L T K D C P N V I S S I C A G T I I T A C K N C A
Core with dehydrations:
A D R G W I K Dhb L Dhb K D Cys P N V I Dha Dha I Cys A G Dhb I I Dhb A Cys K N Cys A

#### MIBiG 3.1 matches for ctg1_654

27.3% BGC0002110 (QKV49893.1): Lanthipeptide: birimositide
2
D R G W I K T L T K D C-P N
15
+ G W T L T K+C P N
15
N G G W C-T L T K E C Q P N
28

#### antiSMASH-DB 4.0 matches for ctg1_654

71.4% NZ_FMXP01000004.1: Lanthipeptides: BLQ04_RS01515_lanthipeptide
1
A D R G W I K T L T K D C P N V I S S I C A G T I I T A C K
30
A D R G W I K T L T K D C P N V I S S I C A G T I I T A C K
1
A D R G W I K T L T K D C P N V I S S I C A G T I I T A C K
30
54.5% NZ_AQQB01000068.1 and 6 others:
NZ_BCEY01000024.1 Lanthipeptides: GOZ53_RS05100_lanthipeptide NZ_BCEZ01000067.1 Lanthipeptides: GOZ55_RS11230_lanthipeptide NZ_BCFC01000053.1 Lanthipeptides: GOZ35_RS07920_lanthipeptide NZ_BCFG01000017.1 Lanthipeptides: GOZ50_RS03220_lanthipeptide NZ_BCFI01000009.1 Lanthipeptides: GOZ54_RS02495_lanthipeptide NZ_CP019557.1 Lanthipeptides: BZG42_RS05725_lanthipeptide
Lanthipeptides: K738_RS01000000110290_lanthipeptide
1
A D R G W I K T L T K D C P N V I S S I C A G T-I I T A C K N C
32
A G +K T L T K D C P +S+I C I+ C K N C
1
A G S G L V K T L T K D C P G F L S N I C V N I G F I S G C K N C
33
51.5% NC_017621.1 and 16 others:
NZ_CP039462.1 Lanthipeptides: E8M06_RS05390_lanthipeptide NZ_JABTZM010000032.1 Lanthipeptides: HRQ47_RS09675_lanthipeptide NZ_JAEVFQ010000010.1 Lanthipeptides: JNO64_RS06375_lanthipeptide NZ_JAFFHD010000003.1 Lanthipeptides: JN532_RS02075_lanthipeptide NZ_JAGFVG010000007.1 Lanthipeptides: J5581_RS04225_lanthipeptide NZ_JAIJZO010000001.1 Lanthipeptides: K5Q34_RS00965_lanthipeptide NZ_JAIMDS010000024.1 Lanthipeptides: K6V32_RS10650_lanthipeptide NZ_JAJUWV010000001.1 Lanthipeptides: LZF89_RS05505_lanthipeptide NZ_JAMDIS010000017.1 Lanthipeptides: M5P45_RS08180_lanthipeptide NZ_JAMYIU010000001.1 Lanthipeptides: NKE44_RS01780_lanthipeptide NZ_JAMYIX010000001.1 Lanthipeptides: NKE54_RS02675_lanthipeptide NZ_JAMYIY010000001.1 Lanthipeptides: NKE64_RS02785_lanthipeptide NZ_JAMYJP010000014.1 Lanthipeptides: NKE68_RS07350_lanthipeptide NZ_LR738722.1 Lanthipeptides: STREPSUIS_RS03955_lanthipeptide NZ_VZMP01000023.1 Lanthipeptides: F6P50_RS09295_lanthipeptide NZ_VZNS01000007.1 Lanthipeptides: F6P79_RS05700_lanthipeptide
Lanthipeptides: SSUD12_RS06540_lanthipeptide
1
A D R G W I K T L T K D C P N V I S S I C A G T-I I T A C K N C
32
A G++K T L T K D C P +S++C I+ C K N C
1
A G S G F V K T L T K D C P G F L S N V C V N I G F I S G C K N C
33
with 37 more sequence matches
48.5% NZ_CP058255.1: Lanthipeptides: HW369_RS18920_lanthipeptide
6
I K T L T K D C P N V I S S I C A G-T I I T A C K N C
32
+ T+T K D C P N +S S+C I+A C K N C
2
V P T I T K D C P N T V S S V C V T F P F I S A C K N C
29
47.1% NZ_FNYB01000007.1 and 1 other:
NZ_KB976303.1 Lanthipeptides: IGY_RS28100_lanthipeptide
Lanthipeptides: BMZ34_RS15340_lanthipeptide
4
G W I K T L T K D C P N V I S S I C A G-T I I T A C K N C
32
G+I+T L T K D C P V I C I C K C
4
G Y I E T L T K D C P R V T P Q I C V P I N G I W T C K R C
33
47.1% NZ_JH792312.1 and 1 other:
NZ_QNRN01000010.1 Lanthipeptides: DET63_RS17570_lanthipeptide
Lanthipeptides: IIG_RS24665_lanthipeptide
1
A D R G W I K T L T K D C P N V I S S I C A G T I I T A--C K N C
32
A G W++T L T K D C P + C T I+ C K C
1
A G P G W V E T L T K D C P W N V P V A C V-T I M G Q R I C K K C
33
47.1% NZ_KB976165.1: Lanthipeptides: ICC_RS24850_lanthipeptide
4
G W I K T L T K D C P N V I S S I C---A G T I I T A C K N C
32
G W++T L T K D C P C A G I C K C
4
G W V E T L T K D C P G Y K P Y A C I T I A G Q T I--C K K C
33
44.1% NZ_CP036100.1 and 1 other:
NZ_CP072062.1 Lanthipeptides: J5V93_RS29280_lanthipeptide
Lanthipeptides: EXW47_RS29185_lanthipeptide
1
A D R G W I K T L T K D C P N V I S S I C A G T I I T A--C K N C
32
A G W++T+T K D C P + C T I+ C K C
1
A G P G W V E T V T K D C P W N V P V A C V-T I M G Q R I C K K C
33
41.2% NZ_CP040409.1 and 4 others:
NZ_CP040414.1 Lanthipeptides: FE331_RS04020_lanthipeptide NZ_CP040415.1 Lanthipeptides: allorf_0721024_0721203_lanthipeptide NZ_CP040417.1 Lanthipeptides: FE328_RS00745_lanthipeptide NZ_CP040424.1 Lanthipeptides: FE321_RS03445_lanthipeptide
Lanthipeptides: FE336_RS03450_lanthipeptide
4
G W I K T L T K D C P N V I S S I C A G-T I I T A C K N C
32
G +K T L T K D C P +S +C +++ C K C
4
G L L K T L T K D C P G T V S D V C V N L A V V S T C K K C
33
36.4% NC_009480.1 and 10 others:
NZ_CP033724.1 Lanthipeptides: EFE39_RS10220_lanthipeptide NZ_CP047051.1 Lanthipeptides: GRD74_RS10365_lanthipeptide NZ_CP047054.1 Lanthipeptides: GRD61_RS10460_lanthipeptide NZ_CP053860.1 Lanthipeptides: DQP62_RS10825_lanthipeptide NZ_CP076352.1 Lanthipeptides: KN218_RS09900_lanthipeptide NZ_CP085137.1 Lanthipeptides: LHJ48_RS10290_lanthipeptide NZ_CP085140.1 Lanthipeptides: LHJ47_RS10305_lanthipeptide NZ_CP095274.1 Lanthipeptides: MU580_RS10460_lanthipeptide NZ_PSTW01000024.1 Lanthipeptides: C5C03_RS09675_lanthipeptide NZ_SISU01000002.1 Lanthipeptides: EOG37_RS09890_lanthipeptide
Lanthipeptides: CMM_RS10575_lanthipeptide
1
A D R G W I K T L T K D C P N V I S S I C A G T I I T A C K
30
+ G W+ T L T +C G T I I A C+
1
S S S G W L C T L T I E C---------G T I I C A C R
21
36.4% NZ_AUBN01000022.1: Lanthipeptides: G448_RS16025_lanthipeptide
1
A D R G W I K T L T K D C P N V I S S I C A G T I I T A C K
30
A G W T L T +C G T I A C+
1
A S S G W F C T L T I E C---------G T F I C A C R
21
36.4% NZ_CP028130.1: Lanthipeptides: C7V51_RS14690_lanthipeptide
1
A D R G W I K T L T K D C P N V I S S I C A G T I I T A C K
30
G W+ T L T +C G T I I A C+
1
G S S G W M C T L T I E C---------G T I I C A C R
21
36.4% NZ_CP061274.1 and 1 other:
NZ_JADKRR010000001.1 Lanthipeptides: ITJ40_RS10085_lanthipeptide
Lanthipeptides: H9X71_RS09850_lanthipeptide
1
A D R G W I K T L T K D C P N V I S S I C A G T I I T A C K
30
A G W+ T L T +C G T I A C+
1
A S S G W L C T L T I E C---------G T F I C A C R
21
33.3% NZ_BMMB01000007.1 and 1 other:
NZ_BMMB01000007.1 Lanthipeptides: IEX62_RS15675_lanthipeptide
Lanthipeptides: IEX62_RS15680_lanthipeptide
4
G W I K T L T K D C P N V I
17
G W I T L T D C P N I
6
G W I T T L T D D C P N S I
19
33.3% NZ_CP018188.1 and 5 others:
NZ_JAQDVH010000019.1 Lanthipeptides: PGU04_RS09335_lanthipeptide NZ_JAQDVH010000019.1 Lanthipeptides: PGU04_RS09335_lanthipeptide NZ_JAQMJT010000006.1 Lanthipeptides: PNU26_RS06620_lanthipeptide NZ_JAQMJT010000006.1 Lanthipeptides: PNU26_RS06620_lanthipeptide NZ_VDNV01000006.1 Lanthipeptides: FSV44_RS08680_lanthipeptide
Lanthipeptides: BSR19_RS10820_lanthipeptide
4
G W I K T L T K D C P N V I S S I C
21
G W I T+T D C P N I C
5
G W I A T I T D D C P N S I F V C C
22
33.3% NZ_CP040409.1 and 4 others:
NZ_CP040414.1 Lanthipeptides: FE331_RS04030_lanthipeptide NZ_CP040415.1 Lanthipeptides: FE330_RS03440_lanthipeptide NZ_CP040417.1 Lanthipeptides: FE328_RS00755_lanthipeptide NZ_CP040424.1 Lanthipeptides: FE321_RS03455_lanthipeptide
Lanthipeptides: FE336_RS03460_lanthipeptide
4
G W I K T L T K D C P N V I S S I C
21
G ++T L T K D C P N V+ +C
4
G L V R T L T K D C P N V V P K V C
21
30.3% NZ_CP036455.1: Lanthipeptides: EKD16_RS25235_lanthipeptide
2
D R G W I K T L T K D C P N V I S S I C A G T I I T A C K
30
G W+ T L T +C G T++ A C+
1
S S G W V C T L T I E C---------G T L V C A C Q
20
30.3% NZ_JAGPXN010000019.1: Lanthipeptides: KBX06_RS22045_lanthipeptide
4
G W I K T L T K D C P N V I S S I C A G T I I T A C K
30
G W+ T L T +C G T++ A C+
3
G W V C T L T I E C---------G T V V C A C R
20
30.3% NZ_MJEH01000022.1 and 2 others:
NZ_MJEH01000022.1 Lanthipeptides: BFG57_RS18360_lanthipeptide NZ_MJEH01000022.1 Lanthipeptides: BFG57_RS09480_lanthipeptide
Lanthipeptides: BFG57_RS18365_lanthipeptide
4
G W I K T L T K D C P N V I
17
G W I T+T D C P N I
3
G W I S T I T D D C P N S I
16
30.3% NZ_NIHT01000008.1 and 1 other:
NZ_NIHT01000008.1 Lanthipeptides: CDL23_RS06740_lanthipeptide
Lanthipeptides: CDL23_RS06745_lanthipeptide
4
G W I K T L T K D C P N V I S S I C
21
G W+ T+T D C P N I C
5
G W L P T I T D D C P N S I F V C C
22
30.3% NZ_PKIA01000004.1: Lanthipeptides: CYK22_RS03780_lanthipeptide
4
G W I K T L T K D C P N V I S S I C
21
G W I T+T D C P N + C
5
G W I A T I T D D C P N S V F V C C
22
29.4% NZ_CM000731.1 and 11 others:
NZ_CP036053.1 Lanthipeptides: EXW64_RS27135_lanthipeptide NZ_CP043834.1 Lanthipeptides: F0362_RS30375_lanthipeptide NZ_JAOPRA010000024.1 Lanthipeptides: OCE16_RS27090_lanthipeptide NZ_KB976276.1 Lanthipeptides: IIC_RS09105_lanthipeptide NZ_KB976667.1 Lanthipeptides: IG5_RS06165_lanthipeptide NZ_LDKD02000003.1 Lanthipeptides: ABH17_RS27060_lanthipeptide NZ_NUAO01000019.1 Lanthipeptides: CN544_RS19345_lanthipeptide NZ_NVFH01000027.1 Lanthipeptides: COL40_RS24675_lanthipeptide NZ_NVHY01000021.1 Lanthipeptides: COM05_RS26660_lanthipeptide NZ_NVOB01000050.1 Lanthipeptides: CON62_RS29235_lanthipeptide NZ_NVOV01000033.1 Lanthipeptides: CON78_RS26470_lanthipeptide
Lanthipeptides: BCERE0020_RS28875_lanthipeptide
1
A D R G W I K T L T K D C P
14
A G W++T L T K D C P
1
A G P G W V E T L T K D C P
14
29.4% NZ_CM000758.1 and 1 other:
NZ_MOOT01000057.1 Lanthipeptides: BK765_RS20265_lanthipeptide
Lanthipeptides: BTHUR0013_RS15850_lanthipeptide
4
G W I K T L T K D C P
14
G W I T L T K D C P
4
G W I A T L T K D C P
14
27.3% NC_004070.1 and 32 others:
NC_008024.1 Lanthipeptides: MGAS10750_RS08460_lanthipeptide NZ_CAAHHZ010000002.1 Lanthipeptides: E9518_RS02835_lanthipeptide NZ_CAAHIH010000002.1 Lanthipeptides: E9602_RS03585_lanthipeptide NZ_CAAHIO010000002.1 Lanthipeptides: E9584_RS04360_lanthipeptide NZ_CAAHJE010000002.1 Lanthipeptides: E9605_RS03435_lanthipeptide NZ_CAAHJS010000002.1 Lanthipeptides: E9628_RS02300_lanthipeptide NZ_CAAHKC010000012.1 Lanthipeptides: E9636_RS08085_lanthipeptide NZ_CAAHMR010000003.1 Lanthipeptides: E9727_RS05510_lanthipeptide NZ_CAAHQE010000003.1 Lanthipeptides: E9931_RS04945_lanthipeptide NZ_CAAHQG010000004.1 Lanthipeptides: E9903_RS05690_lanthipeptide NZ_CAAIFD010000008.1 Lanthipeptides: FAG63_RS07845_lanthipeptide NZ_CAAIJM010000014.1 Lanthipeptides: FAI23_RS09465_lanthipeptide NZ_CAAJDK010000010.1 Lanthipeptides: FAO79_RS08000_lanthipeptide NZ_CAAJFI010000003.1 Lanthipeptides: FAP60_RS03740_lanthipeptide NZ_CAJHJN010000010.1 Lanthipeptides: JMZ68_RS08975_lanthipeptide NZ_CP008926.1 Lanthipeptides: DP15_RS03855_lanthipeptide NZ_CP035434.1 Lanthipeptides: ETT65_RS08240_lanthipeptide NZ_CP035435.1 Lanthipeptides: ETT64_RS07905_lanthipeptide NZ_CP035447.1 Lanthipeptides: ETT52_RS07920_lanthipeptide NZ_CP035449.1 Lanthipeptides: ETT50_RS08255_lanthipeptide NZ_CP035453.1 Lanthipeptides: ETT46_RS08220_lanthipeptide NZ_CP060646.1 Lanthipeptides: H7789_RS07920_lanthipeptide NZ_CP065054.1 Lanthipeptides: I2432_RS09105_lanthipeptide NZ_CP066093.1 Lanthipeptides: I6I02_RS06995_lanthipeptide NZ_JACLQK010000029.1 Lanthipeptides: H7U04_RS10750_lanthipeptide NZ_JADPEB010000003.1 Lanthipeptides: I4U26_RS02855_lanthipeptide NZ_KV832031.1 Lanthipeptides: HMPREF2637_RS05170_lanthipeptide NZ_LRGW01000003.1 Lanthipeptides: AWU01_RS03260_lanthipeptide NZ_LS483298.1 Lanthipeptides: DQM39_RS08650_lanthipeptide NZ_LS483407.1 Lanthipeptides: DQM86_RS08100_lanthipeptide NZ_LS483425.1 Lanthipeptides: DQN36_RS07865_lanthipeptide NZ_LS483430.1 Lanthipeptides: DQN28_RS07600_lanthipeptide
Lanthipeptides: SPYM3_RS08605_lanthipeptide
4
G W I K T L T K D C P N V I S S I C
21
G W T+T D C P N + C
5
G W F A T I T D D C P N S V F V C C
22
27.3% NZ_CP036073.1 and 11 others:
NZ_CP036073.1 Lanthipeptides: EXW45_RS04930_lanthipeptide NZ_CP036073.1 Lanthipeptides: EXW45_RS04925_lanthipeptide NZ_CP036073.1 Lanthipeptides: EXW45_RS04920_lanthipeptide NZ_CP036073.1 Lanthipeptides: EXW45_RS04915_lanthipeptide NZ_CP036073.1 Lanthipeptides: EXW45_RS04910_lanthipeptide NZ_NUEG01000031.1 Lanthipeptides: CN905_RS18915_lanthipeptide NZ_NUEG01000031.1 Lanthipeptides: CN905_RS18910_lanthipeptide NZ_PVRT01000001.1 Lanthipeptides: C6359_RS05275_lanthipeptide NZ_PVRT01000001.1 Lanthipeptides: C6359_RS05270_lanthipeptide NZ_PVRT01000001.1 Lanthipeptides: C6359_RS05265_lanthipeptide NZ_PVRT01000001.1 Lanthipeptides: C6359_RS05260_lanthipeptide
Lanthipeptides: EXW45_RS04935_lanthipeptide
4
G W I K T L T K D C P N V I S S I C
21
G W+ T+T D C P N + C
4
G W L C T V T D D C P N S V F V C C
21
27.3% NZ_CP048273.1 and 3 others:
NZ_CP048273.1 Lanthipeptides: M654_RS18555_lanthipeptide NZ_LT745776.1 Lanthipeptides: B2C81_RS11280_lanthipeptide NZ_LT745776.1 Lanthipeptides: B2C81_RS11275_lanthipeptide
Lanthipeptides: M654_RS18560_lanthipeptide
4
G W I K T L T K D C P N V I S S I C
21
G W T+T D C P N + C
4
G W A C T I T D D C P N S V F V C C
21
27.3% NZ_CP048890.1 and 3 others:
NZ_CP071478.1 Lanthipeptides: J0P05_RS32905_lanthipeptide NZ_LUCO01000008.1 Lanthipeptides: BMBG_RS24280_lanthipeptide NZ_NVLN01000014.1 Lanthipeptides: CON11_RS24965_lanthipeptide
Lanthipeptides: BMG_RS30865_lanthipeptide
4
G W I K T L T K D C P N V I S S I C
21
G W T+T D C P N + C
4
G W S C T I T D D C P N S V F V C C
21
27.3% NZ_JANHJQ010000013.1: Lanthipeptides: NON16_RS14160_lanthipeptide
4
G W I K T L T K D C P N V I S S I C
21
G W T+T D C P N + C
4
G W S C T V T D D C P N S V F V C C
21
26.5% NZ_CM000748.1 and 1 other:
NZ_JAIPUK010000011.1 Lanthipeptides: K9P71_RS26815_lanthipeptide
Lanthipeptides: BTHUR0003_RS30910_lanthipeptide
4
G W I K T L T K D C P
14
G W++T L T K D C P
4
G W V E T L T K D C P
14
24.2% NZ_MOWR01000001.1: Lanthipeptides: BMI76_RS01705_lanthipeptide
4
G W I K T L T K D C P N V I S S I C
21
G W T+T +C P N + C
4
G W S F T I T D E C P N S V F V C C
21
21.2% NZ_AULU01000012.1: Lanthipeptides: H580_RS25790_lanthipeptide
4
G W I K T L T K D C P N
15
G W+ T T D C P
6
G W V C T Y T L D C P G
17
21.2% NZ_CP015515.1 and 1 other:
NZ_PSUO01000011.1 Lanthipeptides: C5C18_RS08595_lanthipeptide
Lanthipeptides: A6122_RS12855_lanthipeptide
1
A D R G W I K T L T K D C P N V I
17
G W+ T L T +C V+
1
G S S G W M C T L T I E C G T V V
17
21.2% NZ_JAJAGO010000028.1 and 1 other:
NZ_JAJAGO010000028.1 Lanthipeptides: LHJ74_RS33590_lanthipeptide
Lanthipeptides: LHJ74_RS33590_lanthipeptide
1
A D R G W I K T L T K D C P
14
+ G W T L T K+C
13
G N D G W W C T L T K E C Q
26
21.2% NZ_KB895893.1 and 1 other:
NZ_KB900614.1 Lanthipeptides: SALPAC6_RS0114155_lanthipeptide
Lanthipeptides: C569_RS0129325_lanthipeptide
2
D R G W I K T L T K D C P N V I
17
G W+ T L T +C V+
1
S S G W V C T L T I E C G T V V
16
18.2% NZ_JAGFVL010000062.1: Lanthipeptides: J5J03_RS19425_lanthipeptide
4
G W I K T L T K D C
13
G W I + T D C
5
G W I P S F T G D C
14
18.2% NZ_JAODUN010000003.1: Lanthipeptides: BXY51_RS10560_lanthipeptide
2
D R G W I K T L T K D C P N V I
17
G W+ T L T +C ++
1
S S G W V C T L T I E C G T L V
16
18.2% NZ_LR134483.1 and 1 other:
NZ_LR134483.1 Lanthipeptides: EL241_RS01725_lanthipeptide
Lanthipeptides: EL241_RS01725_lanthipeptide
1
A D R G W I K T L T K D C P N V
16
++G++ T L T K+C +
11
G N K G Y V C T L T K E C Q K L
26
17.1% NC_015957.1: Lanthipeptides: STRVI_RS53125_lanthipeptide
4
G W I K T L T K D C
13
G W+ T L T +C
24
G W V C T L T T E C
33
16.7% NZ_CP009288.1 and 3 others:
NZ_CP009288.1 Lanthipeptides: PDUR_RS25150_lanthipeptide NZ_CP076607.1 Lanthipeptides: KP014_RS01580_lanthipeptide NZ_CP076607.1 Lanthipeptides: KP014_RS01580_lanthipeptide
Lanthipeptides: PDUR_RS25150_lanthipeptide
1
A D R G W I K T L T K D C
13
+ G W+ T T K+C
19
G N N G W V C T A T K E C
31
15.0% NZ_CM001792.1 and 1 other:
NZ_CM001792.1 Lanthipeptides: C794_RS17980_lanthipeptide
Lanthipeptides: C794_RS17980_lanthipeptide
1
A D R G W I K T L T K D C
13
++G W T+T K+C
21
G N Q G W F C T I T K E C
33

#### Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine
Lanthipeptides
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists the number of lanthionine bridges, possible molecular weights, and the scores for cleavage site prediction and RODEO.

ctg1_654 - Class II
  Cleavage pHMM score: 3.20
  RODEO score: 0
  Monoisotopic mass: 3357.7 Da
  Molecular weight: 3359.9 Da
  Number of bridges: 4
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3378.0 Da N = 1
    3396.0 Da N = 2

gnlProkkaCJPBALEN_1 - Region 4 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 878,276 - 896,043 nt. (total: 17,768 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
KnownClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
gnlProkkaCJPBALEN_1 - Region 5 - RaS-RiPP
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,238,905 - 1,261,329 nt. (total: 22,425 nt) Show pHMM detection rules used
RaS-RiPP: (PF04055 and TIGR01716)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
KnownClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
gnlProkkaCJPBALEN_1 - Region 6 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,522,462 - 1,550,873 nt. (total: 28,412 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
KnownClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.