LOCUS       gnlProkkaLMEFGPDI_59   11259 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LMEFGPDI_59.
ACCESSION   gnlProkkaLMEFGPDI_59
VERSION     gnlProkkaLMEFGPDI_59
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 23:37:09
            Original ID  :: gnl|Prokka|LMEFGPDI_59
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11259
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11259
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[4850:7448]"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4851..7448
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     cand_cluster    1..11259
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11259
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-iii"
                     /region_number="1"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     CDS             complement(52..507)
                     /locus_tag="ctg54_1"
                     /transl_table=11
                     /translation="MYEGISHHKVTCDGIEEAYTESVAKHVNEEASKAIEADLKKTVPR
                     LIKADAALSIENGQFTLDTKWNKQLAEKAPMSMTIQLDTSGLSKTDAAKMAETVRKTLN
                     EKGYTYSNGTIDCMQKDGDGGIGYVKYSIDFLSKAAIQSNDAEELGS"
     CDS             complement(477..740)
                     /locus_tag="ctg54_2"
                     /transl_table=11
                     /translation="MKKLVFGLLAIALFGCGLYIYHVWFGDPFSKNAAEQKLVSYVKQT
                     YPKKEIKITNGVYNAKTSEYVFEATSQSHRYPMCTKGFLIIK"
     CDS             complement(770..1222)
                     /locus_tag="ctg54_3"
                     /transl_table=11
                     /translation="MKRLCIIPCGKKKIWDVQPDAGPVRAEDAYLSPFHQACERYAKTF
                     FDEWVILSAKHGFLRPDDLVSGNYDVTFGTGHPEIMTADELRRQFHEKGFSDIEELVML
                     GGKKYRSVLNAVIGEHQHISWPLSSYKGIGYMLQALNRAVEEKHEL"
     CDS             complement(1418..2395)
                     /locus_tag="ctg54_4"
                     /transl_table=11
                     /translation="MTENFWRELPRPFFVLAPMEDVTDVVFRHVVSEAGRPDVFFTEFT
                     NSESYCHPDGKDSVRGRLTFTEDEQPIVAHIWGDKPENFRKMSIGMAELGFKGLDINMG
                     CPVPNVTQNGKGSGLIRRPEVAAELIQAAKAGGLPVSVKTRLGFTDVDEWREWLTHILK
                     QDIANLSIHLRTRAEMSKVDAHWELIPEIKKLRDEVAPDTLLTINGDIPDRQTGLKLAE
                     QYGVDGIMIGRGIFTNPFAFEKEPKEHSSKELLDLLRLHLDLHDKYSALEARPYKPLPR
                     FFKIYLRGFRGASELRNQCMNTKSTDEVRALLDDFERKYLDGIE"
     CDS             complement(3151..3435)
                     /locus_tag="ctg54_5"
                     /transl_table=11
                     /translation="MDKVYKKRPLYKRSWFQTFLAFLVSQLYFNFVELTGWGPKYREMN
                     GFPANIVELDFFQTYLSFYDNPWFNIITVFLGVFTIIQIITGITKDIRN"
     CDS             complement(3496..3639)
                     /locus_tag="ctg54_6"
                     /transl_table=11
                     /translation="MNNVLALQQLNNSAEVEPQVGPTITTITVIPTMVISLISNYCDNH
                     AS"
     CDS             complement(3894..4025)
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg54_7"
                     /transl_table=11
                     /translation="MKDVLELQQLNEGSDVEASKGKGGLLTLITTVVGTSTISNNCG"
     CDS_motif       complement(3954..4025)
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MKDVLELQQLNEGSDVEASKGKGG"
                     /locus_tag="ctg54_7_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(3894..3953)
                     /prepeptide="core"
                     /locus_tag="ctg54_7_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="0.70"
                     /molecular_weight="1781.1"
                     /monoisotopic_mass="1780.0"
                     /core_sequence="LLTLITTVVGTSTISNNCG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKDVLELQQLNEGSDVEASKGKGG"
                     /leader_location="[3953:4025](-)"
                     /alternative_weights="1799.1"
                     /alternative_weights="1817.1"
                     /alternative_weights="1835.1"
                     /alternative_weights="1853.1"
                     /alternative_weights="1871.2"
                     /alternative_weights="1889.2"
     CDS             complement(4167..4298)
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg54_8"
                     /transl_table=11
                     /translation="MKDVLELQQLSEGSDVEASKGKGGLLTLITTIVGTSTISNNCG"
     CDS_motif       complement(4227..4298)
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MKDVLELQQLSEGSDVEASKGKGG"
                     /locus_tag="ctg54_8_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(4167..4226)
                     /prepeptide="core"
                     /locus_tag="ctg54_8_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="0.50"
                     /molecular_weight="1795.1"
                     /monoisotopic_mass="1794.0"
                     /core_sequence="LLTLITTIVGTSTISNNCG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKDVLELQQLSEGSDVEASKGKGG"
                     /leader_location="[4226:4298](-)"
                     /alternative_weights="1813.1"
                     /alternative_weights="1831.1"
                     /alternative_weights="1849.1"
                     /alternative_weights="1867.2"
                     /alternative_weights="1885.2"
                     /alternative_weights="1903.2"
     CDS             complement(4319..4438)
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg54_9"
                     /transl_table=11
                     /translation="MNEVLELQQLSKGSEVETAGWTLLTTLIGTSTISNSCNK"
     CDS_motif       complement(4388..4438)
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MNEVLELQQLSKGSEVE"
                     /locus_tag="ctg54_9_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(4319..4387)
                     /prepeptide="core"
                     /locus_tag="ctg54_9_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="-1.30"
                     /molecular_weight="2120.4"
                     /monoisotopic_mass="2119.2"
                     /core_sequence="TAGWTLLTTLIGTSTISNSCNK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNEVLELQQLSKGSEVE"
                     /leader_location="[4387:4438](-)"
                     /alternative_weights="2138.4"
                     /alternative_weights="2156.4"
                     /alternative_weights="2174.4"
                     /alternative_weights="2192.5"
                     /alternative_weights="2210.5"
                     /alternative_weights="2228.5"
                     /alternative_weights="2246.5"
                     /alternative_weights="2264.5"
     CDS             complement(4466..4594)
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg54_10"
                     /transl_table=11
                     /translation="MKDVLELQQLSEGSDVEASKGKGGLLTLITTIVGTSTISNNC"
     CDS_motif       complement(4523..4594)
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MKDVLELQQLSEGSDVEASKGKGG"
                     /locus_tag="ctg54_10_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(4466..4522)
                     /prepeptide="core"
                     /locus_tag="ctg54_10_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="0.50"
                     /molecular_weight="1738.0"
                     /monoisotopic_mass="1737.0"
                     /core_sequence="LLTLITTIVGTSTISNNC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKDVLELQQLSEGSDVEASKGKGG"
                     /leader_location="[4522:4594](-)"
                     /alternative_weights="1756.0"
                     /alternative_weights="1774.1"
                     /alternative_weights="1792.1"
                     /alternative_weights="1810.1"
                     /alternative_weights="1828.1"
                     /alternative_weights="1846.1"
     CDS             complement(4641..4760)
                     /locus_tag="ctg54_11"
                     /transl_table=11
                     /translation="MKEVLELQQFNEKSEVEPAAWTVTLTTISVTLSTISNHC"
     CDS             complement(4851..7448)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1030:serine/threonine protein kinase (Score: 73.2;
                     E-value: 4.1e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg54_12"
                     /sec_met_domain="micKC (E-value: 4.7e-142, bitscore: 464.5,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 8.5e-19, bitscore: 57.7,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 4.7e-18, bitscore:
                     54.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKKLVYFQHMSENSKYYIEKSPNVETDPYEVHNMPNYYTVSTEY
                     KSPWKFYNNPNHTLKEQGWKIHISATMNNAQDILKVVSQIIFKHQVPFKHIKDKQSLFN
                     MNSKHGNRTSSGKFITIYPSSNNMFFELLNELYDELKHYENGPYILNDKSWKDSNIYYR
                     YGAFKNIYNERGELCIKDENGNLIPDNRQPYYKIPEFVRDFDQYLDTKNNLFDTQDVSN
                     FNDYEFQGVLRFNNGGGIYTGIRKSDGKKVVIKEGRPKVGLDGQLNDAIDRLNIEYEAL
                     NKLTEVEGVVNVLDYFKAWKHVFLVEEFVKGVTLQSWCAINYPFNIENDKNEYISKVKK
                     IINSLIETIKLVHSKDVGMGDLQPQNIMITPESNIKIIDFEAASALSEENGALQTIGYT
                     NKKNKNHKERDWYALKKVLRFCILPIGPVTDIEASIKKKHDIWIENEFGKDVYQYVVNI
                     ENLCDRYLSDTKEKIFKNNYDSEIKKEMDMSKVINGLRNSIESNMLPNSSLIHGDVRQF
                     VMPSGKLNVLTGGTGAALALYRSGNVNKQVRDWIENVLLKKLHVLNDDIGLFTGRVGIA
                     ATLYELGYIEEAMNLFNNLSYEDMKDISLRSGLSGIGLSLISLYLEEDNDDFLVTSEKI
                     ADQIENRIIEDDKLSATDFAAVPIGLIDGWSGISLFYAALYSVTKKKKYYLKSKEYIEW
                     DLKHCKVDEETNTLQTYDDQNPRLLPYLSGGSIGIGVAIWYLNYVGNNNLFREELEQII
                     NLNKVRIAYSGGLFDGVGSFLLIPAMTKENNEISQQIELALKKLELFLIRKDDQVLFPG
                     NFSFRLADDYYSGSAGIILGINSIQFSNPLYWLPIIKIDSFLNKTKKELLLNN"
     CDS             complement(7478..9250)
                     /gene_functions="resistance (resist) ABC_efflux (Score:
                     258.6; E-value: 7.2e-79)"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 346; E-value:
                     6.7e-105)"
                     /gene_kind="transport"
                     /locus_tag="ctg54_13"
                     /transl_table=11
                     /translation="MMTNPNFKSKEFFFLLRKTRPNIRLFILAIFLSGLSAIASTLVPH
                     YLKSLIDYYNILEKINLWDLLGLLSIFLISGVIGAVGSYMLSVVGYNVVANLRNLLWEK
                     IVILPIEFYDKNRSADIASRFVNDTTVIYNLVSNSFSQFINAILIVLFCGFWLFYYDWQ
                     LTLVIIVAIPVYLLIFIPLGRILSKLSKMTQSLTGELNVRAVETISAIRLIKSSTAEKL
                     QVEKGKEDIEALRNIGLKQTKWMVILNPIINLMMMLIIISIIGFGGVKLANGSLSPGTF
                     IAFLTLMFYIIGPLNNFGLFFTQIQKTIGATERISQLIYEQGEDQHKGKELADTYKDLV
                     IENLSFCYGKEDKAFSLNNINLIIKGGSVNALVGPSGSGKTTIISILERYYNPNSGNIY
                     FGEENIELFSLKSWRSQIGYVAQNHDLISGTIRDNLIFGLENPPDEKKLVEACKKAYAW
                     QFISELPNGLETNIGEKGLNLSGGQRQRIAIARMFLKDPNIIFLDEATASLDSHSEQIV
                     NEAMKKLMKNRTAIIIAHRLSTIINADNIIFMENGEVTGQGNHWELKRSHKLYRQFCEQ
                     QFKEDGTDPLVLTN"
     CDS             9592..11088
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075:alkaline serine protease, subtilase family
                     (Score: 232.6; E-value: 1.8e-70)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg54_14"
                     /sec_met_domain="Peptidase_S8 (E-value: 1.6e-45, bitscore:
                     145.5, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFYKLKVNILIFGRKVNYIQSYYNEMYKGKEYKKMKNLRRISMVF
                     IFVIVSSLHPISSHAKESNYDESIIINLDSKVSESTINKVQENYSNIETNYIKELDLLV
                     IDNIKPSQFSAIKDIAKEKLDAKEIIEDKEISLPDKSKQIPAKVTPTQFTEDNDTLYDS
                     WLWNIKQVTNDYRSYRINKGSHNTKVGVIDSGIDFNHPDLKNNIVDSGESFVPVEDNTQ
                     DFYGHGTSVSGIIAANGSVKGVGPNLGLVPYKVFDKNGKSKTSWVISAIVKATEDDMDV
                     INLSLSTFLSKKDKEDRETIKLFEKAFKFARKHNTLIVAAAGNHGYDISNSKKLAKQLG
                     KPKDNILHLPGGDNDVITVSATTAQNTKASYSNYGKNISIAAPGGDLDPSFLDTNKIDL
                     YSLVWTTSPVNIPQTPLSKSLGFQKGYEPTLGTSVAAPIVTATAALLKTEYYEKYGEEM
                     PIRKVEENLYQNTDHVENLVKNEVGSGIVNAYESLLNIER"
ORIGIN
        1 atcacccggt ctttgacaat gatcgacgta tttatttcct tggaaatgat gtcaacttcc
       61 tagttcctct gcatcgtttg actgaatagc tgcttttgaa agaaaatcaa ttgaatattt
      121 gacatatccg ataccgccgt ccccgtcctt ctgcatacag tctatcgtgc cgtttgagta
      181 tgtatatccc ttttcattaa gcgtttttct gaccgtttcc gccatctttg cggcatctgt
      241 ttttgataac ccgctggtgt ctaactgaat cgtcatactc ataggcgctt tttcagccag
      301 ctgtttgttc cattttgtat ctaacgtgaa ctgtccgttt tcgatactca aagcagcatc
      361 agcttttata agtcgaggaa ccgttttttt cagatctgct tcgattgcct tcgatgcttc
      421 ttcatttaca tgttttgcta ctgattcggt atacgcttct tcaattccat cgcacgttac
      481 tttatgatga gaaatccctt cgtacacatt gggtagcgat gagattggga ggttgcttcg
      541 aatacatatt cagaggtttt agcgttatat accccattcg tgatcttgat ttctttctta
      601 ggataggttt gtttcacata agagactagc ttctgttctg cagcattttt cgaaaatgga
      661 tcaccgaacc atacatgata gatatatagt ccgcatccga ataatgcaat ggcaagcaag
      721 ccaaacacaa gttttttcat gttcccactc ttttcctcat atgtacgtgc tacagttcat
      781 gcttttcttc aacagcccgg ttcagcgctt ggagcatata gcctatgcct ttgtatgatg
      841 atagcggcca gctgatatgc tggtgttctc cgatgacggc gtttagaacg cttcgatatt
      901 tttttccgcc aagcatgact agctcttcga tatcagaaaa gcctttttcg tgaaattgac
      961 ggcgcagctc gtccgctgtc atgatttccg gatgaccggt gccaaaagtg acatcgtaat
     1021 ttcccgaaac gagatcatca gggcggagga acccgtgctt cgccgacaaa atcacccact
     1081 catcgaaaaa tgtttttgca taccgctcgc acgcctgatg aaacgggctg agataagcgt
     1141 cctctgctct taccggcccg gcatcaggct ggacatccca gatttttttc ttgccgcagg
     1201 ggatgatgca tagccgtttc attttcctct ccccctttat atgatatctc cactaaatat
     1261 accattattt tcttacaata aattagagaa aagacaggct gagtaaaagc tgcgtacaaa
     1321 aaagacccgg atttaccgaa aatccaggtt tattttagtc aagaattgtg taaaaatccc
     1381 tttattttgt tagccttttt tgaatcaagc actgcagtta ctctatccca tcaagatact
     1441 ttctctcaaa gtcgtcgagc aatgcacgca cttcatctgt tgactttgtg ttcatgcatt
     1501 gatttcttaa ttcacttgcc cctcggaacc cgcggagata aattttgaaa aagcgaggaa
     1561 gaggcttgta cggacgggct tctaatgctg aatatttatc atgaagatcc agatgcagcc
     1621 ttaagagatc aagcaattcc ttgctgctat gctctttcgg ctccttttca aaggcaaatg
     1681 gatttgtaaa aataccgcgc cctatcataa ttccatcgac gccgtattgt tcagcaagtt
     1741 ttaagccagt ttggcggtca gggatatcac cattgatcgt caaaagtgta tctggtgcca
     1801 cctcatcacg aagtttctta atctccggga tgagctccca atgcgcatct actttgctca
     1861 tttctgctct tgtgcgcaga tgaatagaaa gattggcaat atcctgtttc aaaatgtgtg
     1921 tcagccactc gcgccattcg tctacatccg tgaaaccaag tcttgttttt acgcttacgg
     1981 gcaatccccc tgcttttgct gcttgtatta actctgctgc aacttccggc cggcggataa
     2041 gaccgcttcc cttaccgttc tgtgtcacat taggcacagg acagcccata ttgatatcta
     2101 gtcctttaaa tcctaactct gccatgccaa tactcatttt acgaaagttt tcaggcttat
     2161 ctccccatat atgggctaca attggctgtt catcctctgt aaaagttaaa cggccgcgta
     2221 cgctatcctt cccatccgga tggcaatagc tctctgagtt tgtgaactct gtaaaaaaca
     2281 catccggtct gcctgcttca cttactacat gccggaaaac aacatctgtc acatcttcca
     2341 ttggtgccag tacaaaaaat ggccgtggta attcacgcca gaaattttct gtcataacaa
     2401 aaatcaaatc ctttcattag gggatacggc tatacctgta tctcaatatt aaaaaactga
     2461 ccatgcttct tttacactta tcgcatgcga aagcatttct tatcaatcta tagtaatttt
     2521 tgaacatttc acgtgggatg accatctata cctatttttt atattgtggt taacactggc
     2581 gctgaccttc gtctttctta gtggccttgc ttttgaactt tttggataaa aaggattcca
     2641 acctaaatag aatatcatat gagttctcca tattaccaac gcaaaatatt tgtcctgtta
     2701 ttgaagataa gatatttaac actacaccat atccgtatct ctatatcata tttgcggaaa
     2761 aactaatttc aagagataaa ctttgattaa gcaaattgag ttgggggtgg tataactgag
     2821 tactcaagag aatgaaaaag ctttaactta cggcttgcta ctacttgtga atcacatgga
     2881 gtaaagagga tgagaagaga aaataaaccc ttatttaaaa gaattcaaga acttcaatct
     2941 gaatcatttg ggatttgctc atgatttaga aaataaccaa cgcagcaagt ggcaacctac
     3001 tatatatttg tatagggtta taattcggta atcctgatcc agaaccaata aaatagactg
     3061 ctgactaagt gtcgcagtct tcactcataa gataattaag aaagtgttca ttttctttca
     3121 tcattaaata aggcatcaga agttattgct ttaatttcga atatcctttg ttatccctgt
     3181 aattatttgt ataatagtga aaactcccaa gaaaacagta ataatattaa accatggatt
     3241 atcatagaat gaaagatatg tttgaaagaa atctagttca actatgtttg ctgggaatcc
     3301 attcatttct ctatacttag gaccccatcc cgttaattct acaaaattaa aataaagctg
     3361 agatactaaa aatgccaaaa atgtttgaaa ccaacttctt ttatataacg gtcgtttttt
     3421 atatacttta tccatttagt tatccatttc cttctctgca atacttttta gccaagtgtc
     3481 aatctaaaat ttatattatg aagcatgatt gtcgcaataa ttacttatta aggatataac
     3541 cattgtaggt attactgtaa tagttgttat ggttggtccc acttgcggtt ccacctcggc
     3601 actattattt aattgttgta atgctaatac attattcatt attattcctc cattcttcat
     3661 tttataaatt tagcattttt gattttagtt ctacatataa attaagaact aagtcccttc
     3721 attcattttc cattgacaat aaaaaagaag tatgggatag taaaaagaat ttatacgaaa
     3781 gctaaaattg ttcctttttt tcggaaacag gaaaaggatt ggggtccttt tcctgtttag
     3841 gctttcatat aatgtataac gaccaagcaa acttttttag tgtgtttggt cttttatcca
     3901 cagttgttgc taatagtaga tgtgcctact accgttgtga ttagcgtaag caagccacct
     3961 ttgccttttg aagcttctac gtcagatcct tcattgagtt gttgaagttc caatacatct
     4021 ttcatttggt ttcatctccc ttttattatt tattacaact ttgctaatag taaatgtacg
     4081 atgagtgtta ttagaagtgc ccactcattg ttcctacttc agcacttgat gtacgtaaga
     4141 aaatcttttt tgttatgtgt ggccttttat ccacagttat tgctaatagt agatgtgcct
     4201 actatcgttg tgattagcgt aagcaagcca cctttgcctt ttgaagcttc tacgtcagat
     4261 ccctcactga gttgttgaag ttccaataca tctttcattt ggtttcatct cctttttatc
     4321 atttattaca actattgcta atagtagatg taccgatgag tgttgtcaga agtgtccacc
     4381 cagctgtttc tacttcagaa cctttactca attgttgtaa ctctagtact tcattcattt
     4441 gttcatccac ccctcttaat tacccttaac agttattgct aatagtagat gtgcctacta
     4501 tcgttgtgat tagcgtaagc aagccacctt tgccttttga agcttctacg tcagatccct
     4561 cactgagttg ttgaagttcc aatacatctt tcatttggtt tcacctcctt tcaagtactc
     4621 tttcttagat tatgcttcaa ttagcaatga ttgctaatgg tagataatgt aacagaaata
     4681 gttgttagag taacagtcca tgccgcaggc tctacttcag atttttcatt aaattgttga
     4741 agttctaaca cctctttcat tttcttttct cacctccttc gtaagttctg tatattaact
     4801 actttaattc caatcttcaa tgattatcat tcaactataa gtgttagagt ttaattgttt
     4861 aacaacaatt cttttttagt cttatttaag aaactatcaa tttttattat tggcaaccaa
     4921 tataacggat ttgagaactg gatagagttt atgcccaata ttatgccagc acttccggag
     4981 tagtaatcat ctgctaaacg aaaactgaag tttccaggga ataatacttg atcatctttg
     5041 cggataagaa acaattctag ttttttcaat gccagctcaa tctgctgact gatttcatta
     5101 ttttccttag tcattgccgg gattaataag aaactaccta ccccatcaaa caatcctcca
     5161 ctatatgcaa ttcttacttt atttaaattg attatttgct ctaattcttc tctaaataaa
     5221 ttattatttc ctacataatt taaataccaa atagcaaccc ctattccgat tgatcctcct
     5281 gataaatagg gtaataatcg agggttttga tcatcatacg tttgcaaagt attcgtctct
     5341 tcatctacct tacaatgttt taaatcccac tcaatatatt cttttgactt taaataatac
     5401 ttttttttct tagtaactga atataatgcc gcataaaata aagatattcc tgaccaacca
     5461 tcaatcaaac ctataggtac tgctgcaaaa tcagttgctg ataatttatc atcttcaata
     5521 atcctatttt ctatctgatc agcaattttt tcagaagtaa ccaaaaagtc atcattatct
     5581 tcctccaagt ataagctaat taatgaaaga cctattcccg acaatcctga ccttaatgaa
     5641 atatctttca tatcttcata tgacagatta ttgaataagt tcatagcttc ctctatgtac
     5701 cctaattcat acaatgtagc tgcgatacca actcgtcctg taaataaccc aatatcatca
     5761 ttaagtacat gcaatttttt tagtaaaaca ttttcaatcc aatcccgaac ttgcttgttg
     5821 acgtttccag atctgtacaa tgccaatgca gctccagttc ctcctgttag tacatttaac
     5881 tttccagatg gcattacaaa ttgccgcaca tcgccatgaa ttagcgagct gttgggcaac
     5941 atattactct ctatgctgtt tctcaatcca tttataactt ttgacatgtc catttctttt
     6001 ttgatttcac tgtcataatt attcttgaat atcttttctt tggtgtcaga taagtatctg
     6061 tcacatagat tttctatatt tacaacatat tgataaacat ctttaccaaa ttcattctct
     6121 atccaaatat catgtttctt tttaatgctt gcttctatat cagtaactgg acctattggt
     6181 agaatacaaa atcttaaaac tttctttagt gcataccaat ctcgctcctt atgattctta
     6241 tttttcttat ttgtatagcc aattgtttgc aacgctccat tttcttcaga gagagcacta
     6301 gcagcctcaa aatcaataat cttaatattt gattcggggg taatcattat attttggggt
     6361 tgcaaatctc ccatacccac atctttacta tgtactagtt taattgtttc tatcaagcta
     6421 ttaattattt ttttcacctt actaatgtat tcatttttat cattctcaat gttgaacgga
     6481 taattgattg cacaccatga ttgaagggtt acacctttta caaattcttc aactaaaaat
     6541 acatgtttcc atgctttaaa gtaatcgagc acatttacaa caccttcaac ttctgtaagt
     6601 ttatttaatg cttcgtattc tatattcaat ctatcaatcg catcatttaa ttgaccatct
     6661 aatcctactt tgggtctccc ttctttgatc accacttttt ttccatctga ttttcttatt
     6721 cctgtatata taccgccacc attgttaaac ctgaggactc cttggaactc ataatcatta
     6781 aaattactta catcttgagt atcaaataag ttattcttgg tatctaaata ttgatcaaaa
     6841 tctcttacga attcaggtat tttataatat ggctgcctat tatctgggat taaatttcca
     6901 ttttcatctt taatgcacag ttctcctctt tcattgtaaa tattcttaaa tgctccgtat
     6961 cggtaatata tattgctgtc cttccatgat ttatcattta agatgtatgg tccattctcg
     7021 tagtgtttta attcatcata aagttcattt aataactcga agaacatgtt attagaggaa
     7081 ggatagatag tgataaattt tccagatgaa gttcgattac catgctttga attcatatta
     7141 aatagagatt gtttatcttt aatatgctta aatggtacct gatgtttaaa tataatttga
     7201 ctcacaactt ttaatatatc ctgagcatta ttcattgtcg cacttatgtg tattttccag
     7261 ccttgttctt tgagcgtatg attgggatta ttataaaact tccacggtga tttatattcc
     7321 gtactaacag tatagtaatt tggcatatta tgtacttcgt atggatcagt ttctacattt
     7381 gggcttttct ctatatagta ctttgaattt tcactcatgt gttggaaata aactaatttt
     7441 ttgtccattt tgttctcgcc tctcttaagc gctcttttta attggttaat actaatggat
     7501 cggtaccatc ttctttaaac tgctgctcac agaattgacg atacaattta tgactacgct
     7561 ttaactccca atgattccct tgacctgtta cctcaccatt ttccataaaa atgatattgt
     7621 cagcgtttat aatggtggat aacctgtgtg ctattataat agcggttcta ttcttcatga
     7681 gtttcttcat tgcttcgttc acaatttgtt cagaatgact gtcaagactt gcagttgctt
     7741 catccaagaa aattatattt ggatccttca gaaacattct cgcaatagca attctttgtc
     7801 gttgtcctcc tgataagttc agaccttttt ctccaatatt agtttctaac ccgttaggca
     7861 attcacttat aaattgccat gcatatgcct tcttacatgc ttctactaat tttttttcat
     7921 ctggaggatt ttctaaacca aatatgagat tgtctctaat agtaccactt attaaatcgt
     7981 gattctgtgc tacatatcct atttggctac gccatgattt taatgaaaat aactcaatat
     8041 tctcttcacc aaaataaata tttccgctat taggattata atatctttcc agaatagaga
     8101 tgattgtggt tttaccactc ccactaggac ctactaaggc atttacactt ccccctttta
     8161 ttattaaatt aatattattc aaggaaaatg ctttatcctc tttaccatag caaaatgata
     8221 aattttcaat cactaaatct ttataggtgt ccgctaattc ttttccttta tgctgatctt
     8281 ctccttgctc atatatcaat tgagaaattc tttctgttgc acctatcgtc ttttgtattt
     8341 gagtaaagaa taacccaaag ttattaagtg gacctatgat atagaacata agtgtcagaa
     8401 atgctataaa tgttcctggc gataaacttc cattggctaa tttaacccct ccgaatccaa
     8461 tgatgctaat aatgataagc atcatcatta aattaatgat agggtttaaa ataaccatcc
     8521 attttgtttg ctttaagcct atattcctta aagcttcaat atcttctttt cctttttcta
     8581 cctgtaattt ttctgcagtt gaagatttaa tcagtcttat tgcggatatt gtttcaacag
     8641 ctcttacatt taattctcct gttaagcttt gtgtcatttt agataattta gataaaattc
     8701 ttcctaaagg tataaaaatc aacaaataaa ctggaattgc tactataatc actagtgtca
     8761 attgccaatc atagtaaaac aaccaaaatc cacaaaaaag cactattaat atagcattaa
     8821 taaattgtga aaaagagtta cttaccaagt tgtaaatcac cgtagtatca ttaacaaatc
     8881 tacttgctat atctgcagaa cgattcttat cgtaaaattc tataggtaat ataactatct
     8941 tttcccataa taaatttctg agatttgcaa caacgttata tcctactaca cttaacatgt
     9001 aactaccaac tgccccaatt actccgctga ttaaaaatat tgacagaagg cctaaaagat
     9061 cccataaatt gatcttttca agaatattat aatagtctat tagacttttt aaataatgag
     9121 gcactaaggt agaagctatt gcgcttaatc cacttaaaaa tattgccaat ataaataatc
     9181 ttatattcgg tctggttttt ctcagtaaga agaaaaactc tttcgattta aaatttgggt
     9241 tggtcatcat tttcacctct ttcttttatt ccaatgttca actattaaat cgaatgactc
     9301 ttgaaatgat atacgccata ccttacctta tattcctata aacaatattt cacacctaat
     9361 aactgcaagt caatatataa ttttacaaat tatgaaaaaa caggtctttg gttttagatt
     9421 attctactca tgtatattat agatgtgtat atttactcat agtgattttc acctacaaaa
     9481 acatagatgt agtataaaag aataatcaaa aatttaaatg cgtcatacta aaggtaattt
     9541 ttttgggatg attaccgata tttagaaaaa tatgtgttga ctgatttact tatgttttat
     9601 aaacttaaag tcaatatact tatatttgga aggaaggtaa attatataca atcctattat
     9661 aatgaaatgt ataaaggaaa ggagtataaa aaaatgaaga atttaagaag aatttcgatg
     9721 gttttcatat ttgtaattgt atccagttta caccctataa gctctcatgc taaagaatca
     9781 aattatgatg aatctatcat aattaaccta gactcaaaag taagtgaatc gacaataaac
     9841 aaggttcagg aaaattattc aaatatagaa acaaattata ttaaagaact agatttattg
     9901 gttatagata atataaaacc aagccaattt tcagcaatca aagatattgc taaagaaaaa
     9961 ttagacgcaa aagaaattat tgaggataaa gagatttctc ttcctgataa aagtaaacag
    10021 attcctgcta aagtgacacc aacacaattc acagaagata atgacactct ttatgacagt
    10081 tggttatgga atatcaagca agttacaaat gattatcgaa gttatcgtat aaataaagga
    10141 tctcataata caaaagtagg agtaatcgat tcaggcatag atttcaatca tccagacctc
    10201 aaaaataata ttgtagatag tggagagtct tttgttccag ttgaagataa tacacaagac
    10261 ttttatgggc atgggacttc tgtgtctggg ataattgctg ctaatgggag tgtaaaagga
    10321 gttggaccaa atcttggttt agtgccgtat aaggtatttg ataaaaacgg taaatctaaa
    10381 acaagttggg ttataagcgc aattgttaaa gctacggaag atgatatgga cgtaattaat
    10441 ttaagtttat ctactttctt atcaaaaaaa gataaagaag atagagagac tataaaactt
    10501 tttgaaaaag cctttaaatt cgctagaaaa cacaatactt taattgttgc agcagctgga
    10561 aaccatggat atgatatctc aaattcaaaa aaacttgcaa aacaattagg aaaaccaaag
    10621 gacaatatcc tacatcttcc tggtggagat aacgatgtaa ttactgtatc tgccaccaca
    10681 gcgcaaaata caaaagcttc ttactcaaat tatggaaaaa atatctcaat tgcagctcca
    10741 ggtggtgatc ttgacccaag ttttctggat acaaataaga ttgatctata tagcttggta
    10801 tggactactt cccctgtaaa tatcccgcaa actccgctaa gtaaatcact aggctttcaa
    10861 aagggatatg aacctacttt agggacaagt gtagcagctc caatagtaac tgctacagca
    10921 gccctattaa agacagaata ctacgaaaaa tatggagagg agatgccaat tcgtaaggtt
    10981 gaagaaaact tatatcaaaa cacagatcac gttgaaaact tagttaagaa tgaagttggt
    11041 agcggtatcg taaatgctta cgaatcattg cttaatattg agagataata gaagatatta
    11101 agcagtcatc gaaataaaaa aattactaga cgataatgat ctatgaagct agagatgaaa
    11161 tacgtattta tgagatcttg agaataacta aacaagttga tttcacaagc aacttactat
    11221 tactaagttg cttgtgaaat attttattac agcctaagt
//
