GCA_048565635.1 - 5 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

gnlProkkaCADGIAKC_1 (original name was: gnl|Prokka|CADGIAKC_1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1.1	T3PKS	698,253	739,422

gnlProkkaCADGIAKC_2 (original name was: gnl|Prokka|CADGIAKC_2)

Region	Type	From	To	Most similar known cluster		Similarity
Region 2.1	terpene	26,216	47,097

gnlProkkaCADGIAKC_9 (original name was: gnl|Prokka|CADGIAKC_9)

Region	Type	From	To	Most similar known cluster		Similarity
Region 9.1	RiPP-like	84,425	96,575

gnlProkkaCADGIAKC_11 (original name was: gnl|Prokka|CADGIAKC_11)

Region	Type	From	To	Most similar known cluster		Similarity
Region 11.1	cyclic-lactone-autoinducer	14,950	35,655

gnlProkkaCADGIAKC_12 (original name was: gnl|Prokka|CADGIAKC_12)

Region	Type	From	To	Most similar known cluster		Similarity
Region 12.1	NRPS	29,751	57,005	mutanocyclin/leuvalin/tyrvalin	NRP	30%

Region	Type	From	To	Most similar known cluster	Similarity
Region 1.1	T3PKS	698,253	739,422
Region 2.1	terpene	26,216	47,097
Region 9.1	RiPP-like	84,425	96,575
Region 11.1	cyclic-lactone-autoinducer	14,950	35,655
Region 12.1	NRPS	29,751	57,005	mutanocyclin/leuvalin/tyrvalin	NRP	30%

Compact view

gnlProkkaCADGIAKC_1 - Region 1 - T3PKS

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Location: 698,253 - 739,422 nt. (total: 41,170 nt) Show pHMM detection rules used

T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

NRPS/PKS domains

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaCADGIAKC_2 - Region 1 - terpene

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Location: 26,216 - 47,097 nt. (total: 20,882 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaCADGIAKC_9 - Region 1 - RiPP-like

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Location: 84,425 - 96,575 nt. (total: 12,151 nt) Show pHMM detection rules used

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaCADGIAKC_11 - Region 1 - cyclic-lactone-autoinducer

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Location: 14,950 - 35,655 nt. (total: 20,706 nt) Show pHMM detection rules used

cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

Gene overview

KnownClusterBlast

Gene/CDS overview

Filter:

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaCADGIAKC_12 - Region 1 - NRPS

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Location: 29,751 - 57,005 nt. (total: 27,255 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

Gene overview

NRPS/PKS domains

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters from MIBiG 3.1

Module view

Legend

NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 29750 - 57005:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Thr)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg12_55

Search NORINE for peptide: strict or relaxed

AMP-binding (447..839): Thr

nrpys: Thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: thr (Thr)
Single AA prediction:: thr (Thr)

Stachelhaus prediction details:

Stachelhaus sequence:: DYFTLGLVVK
Nearest Stachelhaus code(s):: Leu DYFTFGLIIK (68% 8Å match); OMe-Trp DAFTLGCVFK (56% 8Å match)
Stachelhaus code match:: 70% (weak)