LOCUS       gnlProkkaAIBPMHGB_18   10446 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AIBPMHGB_18.
ACCESSION   gnlProkkaAIBPMHGB_18
VERSION     gnlProkkaAIBPMHGB_18
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 23:03:16
            Original ID  :: gnl|Prokka|AIBPMHGB_18
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 974
            Orig. end    :: 11420
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10446
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[5000:5446]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5446
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..10446
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10446
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             complement(787..1587)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_4"
                     /sec_met_domain="Abi (E-value: 7.8e-13, bitscore: 40.2,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKKRQQLFTPGLRVLYIFILDELIEAFVFTPFLNFLQLNFWADI
                     VLYKVLSLVAILGLNLLLLRQKIIFRTSFGWPSWQKFVFWDIVGCLVAWQIFTNRNFLD
                     ILQASVIGTIAAVPEEYLYRGVIFGGLLRAFYLANRGGTRRNFIYCMLLSSLAFSLAHL
                     SNLPSQGAVATVGQMIQVSGMGMLLAALYVRYGTLLMPIFVHFMIDFLVTLIHGPYPSK
                     LNGVSDETTLITVSLIWDTIYLVISMWVLWHCHDKEGFMARLSK"
     CDS             complement(1872..2171)
                     /locus_tag="ctg18_5"
                     /transl_table=11
                     /translation="MADRTSLLDRFVPNIGTRKCEVGSRVLRCLSCDLPLDLDWLGKGH
                     DEMHRIKNDDLQQMIDGMTWRKFLTMLILGLIAIDAWSHTDQIIAGFLKGWQGM"
     CDS             complement(2146..2478)
                     /locus_tag="ctg18_6"
                     /transl_table=11
                     /translation="MNMIQRNKVYFIMTGLNESFQQTATVSVMNTDAQEVIDDALHILE
                     KENMLQNRAIDYALARLYSRFVRLIGLQGMKLSPEADQWWQQLKDFMENDIHEELSQVG
                     GPHFIT"
     CDS             complement(2730..2921)
                     /locus_tag="ctg18_7"
                     /transl_table=11
                     /translation="MAMTLNKAIHYLLLIGISGVFLFTLAAAIGWVNQGDFALPLLLLA
                     AGLTLLREADAGNEKARH"
     CDS             complement(3236..3571)
                     /locus_tag="ctg18_8"
                     /transl_table=11
                     /translation="MTDKRETLMSMLSRAYANPTIKAEPALRALIETNAKKVDEGDDDK
                     AYVTAVTQLSHDISKYYLIHHAVPEELVAVFNYIKKDVPAADIDAAHYRAQALAAGLIA
                     IPIVWGH"
     CDS             complement(3690..4286)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Mac"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1156:Chloramphenicol acetyltransferase (Score: 107.6;
                     E-value: 1.1e-32)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_9"
                     /sec_met_domain="Mac (E-value: 1.9e-10, bitscore: 32.4,
                     seeds: 568, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLEEKFAFMATGKPYDDMDPLLLAVRDEATAKTDALNNEHDPAK
                     RNALFRKLVGQTGFKPFVNPNFHCEFGRNIRVGDHFYANYDCTILDGAPVTIGNHVLFG
                     PKVGLYTSNHLFDPLERQLGGCIAKPIVVGDGCWLAANVTVLPGVTIGAGTIIGAGSVV
                     THDIPARVIAAGNPCEVLREITAADKTGFAGHDMI"
     CDS             complement(4557..4865)
                     /locus_tag="ctg18_10"
                     /transl_table=11
                     /translation="MDKIISIIIVILILLATIAFYLAPFVGGLWQGAARSKVIAKILLL
                     NRDLKLSSKGLSRLINPQNPYIVLTTLDGRLDFTFISMSNLKKLKSELMSLEIKSMD"
     CDS             complement(5001..5216)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_11"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 2.1e-09,
                     bitscore: 29.2, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISKEVGITLKQHDLVLIQGGAKRRNKPSGCIVSTIGGAVAGAAG
                     LNPFTTVAGAAIGLSLCLSTNYIHPA"
     CDS             complement(5213..5446)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_12"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 4.7e-15,
                     bitscore: 47.3, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYNYRQLDDFQLSGVSGGKKKFDCAATFVTGITAGIGSGTITGL
                     AGGPFGIIGGAVVGGNLGAVGSAIKCLGDGMQ"
     CDS             complement(5718..6671)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039:aldo/keto reductase family oxidoreductase (Score:
                     223.4; E-value: 6.2e-68)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_13"
                     /transl_table=11
                     /translation="MKQVRLGGSNWQASSVALGIMRMNVLAPDKAANVLDSAYNDGINF
                     IDSADIYGQGKSEEVFGEALKQASVSRDQLFIQSKVGIVVDSKRSHGSLVFGKRYDFSK
                     DHLLSAVDHILKRLQVDYLDSVLLHRPDPLMEVDDVAAAFDALEQSGKVRHFGVSNFNP
                     EQIALLESGIRQPLLIDQVQFSVAHTGMVNAGMHTNMADAASVDHDGSLLPYLQRKHMT
                     LQAWSPFQYGMFEGTFIDSPKFKALNDELQKVADHYHTNKNAIAVAWLLRHPVGVQVIL
                     GSMNPEHIKESAEGADITLTRQEWYDIYFAAGNDLP"
     CDS             6876..7610
                     /NRPS_PKS="Domain: PKS_KR (6-169). E-value: 4.9e-12. Score:
                     38.0. Matches aSDomain: nrpspksdomains_ctg18_14_PKS_KR.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     192.7; E-value: 1.3e-58)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_14"
                     /sec_met_domain="adh_short (E-value: 6.6e-35, bitscore:
                     112.2, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVKDKVVVITGASSGIGAATVQVLAEAGAKLVIGARRTERLAEL
                     AASFTNGQVLYQQTDVTDQQQVKALIDLALDKFGHVDVLYNNAGLMPLSEMAELKVNEW
                     ERMIDVNIKGVLYGIAAVLPPMIAQHSGQIITTDSVAGHIVHPGTAVYSGTKWAIQAIM
                     DGLRQEQAANHIKTTMISPGAVNTELFSTITDPKRREAVEADEKNNGLSASDVAKAVLY
                     AIDQPANVAINEVLLRPVTQER"
     aSDomain        6894..7382
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg18_14_PKS_KR.1"
                     /evalue="4.90E-12"
                     /label="ctg18_14_PKS_KR.1"
                     /locus_tag="ctg18_14"
                     /protein_end="169"
                     /protein_start="6"
                     /score="38.0"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VVVITGASSGIGAATVQVLAEAGAKLVIGARRTERLAELAASFTN
                     GQVLYQQTDVTDQQQVKALIDLALDKFGHVDVLYNNAGLMPLSEMAELKVNEWERMIDV
                     NIKGVLYGIAAVLPPMIAQHSGQIITTDSVAGHIVHPGTAVYSGTKWAIQAIMDGLRQE
                     "
     CDS_motif       6897..6977
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg18_14_0001"
                     /evalue="1.90E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg18_14"
                     /protein_end="34"
                     /protein_start="7"
                     /score="14.1"
                     /tool="antismash"
                     /translation="VVITGASSGIGAATVQVLAEAGAKLVI"
     CDS             7636..8799
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217:NADH:flavin oxidoreductase/NADH oxidase (Score:
                     291.3; E-value: 1.5e-88)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_15"
                     /transl_table=11
                     /translation="MSGYHFLKPFTFKHQTITLKNRIVIPPMTTRLSFEDGTVTRDEIR
                     YYQQRAGGVGMFITGTANVNALGKGFEGELSVADDRFIPGLSKLAAAMKTGGTKAILQI
                     FSAGRMSNSKILRGEQPVSASAVAAPRAGYETPRALTSAEIEATIHDFGQAVRRAILAG
                     FDGIELHGANTYLIQQFYSPNSNRRTDEWGGDRDKRMRFPLAVVHEAEKVIATIADRPF
                     LLGYRISPEELEQPGITLDDTLALIDTLKQTKIDYLHVSQSDVWRTSLRNPEDTAIMNE
                     QIRDHVAGAFPVIVVGGIKTPADAEKAAESFDLVAIGHEMIREPHWVQKVLDHDEKAIR
                     YQIAPADLEELGIAPTFLDFIESISGGAKGVPLTTAQSVTSSNVTQD"
     CDS             complement(9061..10437)
                     /locus_tag="ctg18_16"
                     /transl_table=11
                     /translation="MSKYRTETDTLGPVEIPANALWGPQTERSRHNFQAGPLMPMPVIR
                     ALLQLKKAAARANVAADVLPAPKGQLITRAVDALLALPDEKLQKDFPLHVYQTGSGTQT
                     NMNVNEVISHQAAKLNPDLPILPNDDVNHSQSSNDTFPTVMNITAAIAVNQLLHAVNQL
                     CSVLYSKAVTYARVVKIGRTHLQDATPLTFGQEISGWVAMMEHDQIALKQLQPNLFYLA
                     IGGTAVGTGLNADPNFGKIVAGRLSDVYQLPLSAKTNKFAALAAHSEISVVHGAIKTLA
                     ADLLKIANDIRFLASGPRAGYGELRIPANEPGSSIMPGKVNPTQAEALTMAAVRVMGND
                     TTITVAASQGNFELNVYKPVIISTFLESADLLTKTVTSFTEKLAAGLTIHAPHMRALVD
                     HSLMLVTALAPHIGYEKSAAIAQLAEQENLDLKAAAIKSGDVTAAQFDKWVDPLKMTRA
                     "
ORIGIN
        1 tgcatacaag cagttgaaac aaccactgtc aatgtggatc attaattgtt gcttagtggc
       61 gttgctcttt cttgttcccg atgattcaag tatctttgtc tatatcgtga ttgacctcgc
      121 aatcgttgct aacggttttg atttattaaa gaaactattt ggtctgtcaa agcatgcgga
      181 ctggcaccac aacacttgga atcgtgatga atcaaaataa gcctacaaac taagcgtcgc
      241 ctcgtcatcg cttaatttgt aggcttgttt ttttgacttt tttcacacac cacaataaaa
      301 ataacgagaa agatcaaata gtagcgatca ataaatgaaa tgtgaggtaa taaatctaga
      361 tcacttaaaa tcagccaaac tatagcaaat aaaaagccgc caccaacaat aaagctgctc
      421 acttttctaa aactcataaa cagacccact ctctatcatt cttcaacaag gttcgttttt
      481 ggcaataacg caaacagttc attcaccgat tgggagatta aatgcattca gacgttatga
      541 tctgtatctg attcacttct tcttttcatc agatgcacac aggctgtcca gacatggcgc
      601 caatgtacat agaagtaata atggtagtac aaaatcacca tgattagtcc agccgattgc
      661 tgatgtcact gtataggtcc gataggagaa tgcctccaat aatcaggcag atcttgaatg
      721 cttttgccat tcgaatcccc ttttcggtta actaagttcc tcagtcgtgc tgttccgaca
      781 taaacctcat tttgacaacc ttgccatgaa cccttctttg tcatgacagt gccataggac
      841 ccacatggaa atgaccaagt aaatcgtatc ccagatcaac gaaacagtta tgagcgtcgt
      901 ttcgtcactt accccattta atttgctggg ataagggccg tgaatcagcg ttaccaagaa
      961 gtcgatcatg aaatgaacaa agatcggcat cagtaatgtg ccataacgaa cgtagagagc
     1021 agccagcagc atgcccatcc cgctgacttg aatcatctga cccacagttg caacagcacc
     1081 ttggcttggc agattactca agtgtgcaag cgaaaacgcc agactgctta gtaacatgca
     1141 atagataaag ttgcgcctgg taccaccacg gttagcaagg taaaaggcgc ggagcaagcc
     1201 accgaaaata actccgcgat ataggtactc ttcaggaaca gcggcgatgg taccaatgac
     1261 acttgcttgt aaaatatcta agaagtttcg gttggtaaag atttgccaag ccacaaggca
     1321 gcccacaata tcccagaaca caaatttctg ccagcttggc cagccaaatg acgtcctaaa
     1381 gataatcttt tgtcttaaca gcaacagatt gagtccaaga atggcaacta aactaagcac
     1441 cttatagagc acaatgtctg cccaaaaatt cagctgtaga aaattcaaaa atggggtgaa
     1501 cacaaatgct tctataagtt catccaagat aaaaatgtat aaaacacgta atccaggcgt
     1561 gaacaactgt tgccgtttct ttttcattcc gtcaccttca ttcaagttta caaagccggc
     1621 atttttacga cattgctatg aacaatatac caattaatga atggcgttta gtcaactaat
     1681 tttaaacgtc gtgttttcgc catttaacgt tgacgatcat ccgtcaaaaa ttcgctagcg
     1741 gtcatttatt gacaaaaaaa gccacttcac tcggcaaacg acgctacgct aagccaagaa
     1801 gaagtgacgc tgcagtgttg aaaaagtcgc ggagcttgca attggcgcaa ttcttcaccg
     1861 gtcacaaaca cctacatgcc ctgccatccc tttaaaaacc ccgcaataat ttggtcagtg
     1921 tgtgaccaag catctatcgc aatcaatcct aaaatcagca ttgtcagaaa tttacgccag
     1981 gtcatcccgt caatcatttg ttgcaaatca tcattcttta ttcgatgcat ctcatcgtgc
     2041 cccttcccca accagtctaa atcaagtggt aagtcacagg ataaacagcg taacactcga
     2101 cttccgactt cgcatttgcg tgtgccaata ttgggaacaa accgatcaag taatgaagtg
     2161 cggtccgcca acctgactca gctcttcatg aatatcattc tccatgaaat ctttcagttg
     2221 ttgccaccat tgatcagctt ccggcgataa tttcatcccc tgcaacccaa ttaagcgaac
     2281 aaagcgagaa tacaggcgag ctaatgcgta gtcaatggct ctattttgaa gcatattttc
     2341 tttttccaaa atgtggagcg catcatcaat gacctcttgt gcatcggtat tcatgacact
     2401 gacggttgca gtctgctgaa agctttcgtt gagccctgtc ataataaaat agactttatt
     2461 tcgctgaatc atgttcatga tatgtcacca tttcctttga tgtcgtgaca atttttctat
     2521 agaaatgttt gaaaagtatc gatgctatag cttttaggca aagcaccgga aaacaatggc
     2581 tttatagccc gactgatgga tcttgatacc gtcttgtatt tgaactcttt tagatatgag
     2641 tcatcgtaac cgattacatt ttaaaatcag tttgtccttg tgtacagaaa ttcggcctca
     2701 cgtttttctg ccttctaagc agacccaatt caatgcctcg ctttttcatt tccagcatca
     2761 gcttcccgca acaacgtgag tcctgccgcc aaaagcagta gtggcagcgc aaagtcacct
     2821 tggttgaccc agcctatggc ggcagccagc gtaaaaagaa agacaccact gatgcctatc
     2881 agtaaaagat aatgaattgc tttattcaac gtcatcgcca acttgtatcc ccccgtccag
     2941 atgaacttcg actttttctc gcggatgctt ttacgcacac tatactggat agttcacaca
     3001 acagcgcaaa ctttttttaa acgtagggtt ttgcccgatt aacgtcgctt ttttgtcaaa
     3061 tatcgaccaa attttctctt tatcgatctg ctactcggtt tttcttaact ggtgtcaaca
     3121 agtttcatgg caaaaaaata gccgcagatc ttagtctgcg acgttttttg gcaaatgata
     3181 actgattgat catcaactct agcctcaccg tttaaaattc acagccccac ctcggctagt
     3241 gtccccaaac aataggaatg gcgattaagc cggctgccag tgcttgtgca cgataatgtg
     3301 ctgcatcaat atcggcagca ggtacatctt ttttgatgta attgaagacg gccaccagct
     3361 cttctggtac ggcgtgatga atcagatagt atttggaaat gtcgtgggac aactgagtga
     3421 cagccgtcac ataagcctta tcgtcatcac cttcatcaac ctttttggcg ttggtttcga
     3481 taagcgcccg taatgccggc tctgctttga tcgttgggtt agcgtatgcc ctgcttagca
     3541 tcgacattaa agtttcacgt ttatctgtca tcctgcactt cctttcgatg attaacttgg
     3601 caattcatgc tcactcggag caccttagtc tttgtgaata ttgttaggat gcgcttgtca
     3661 attgctaatt tcaagtatcg atttggcgtt tagatcatgt catgccctgc aaaccctgtt
     3721 ttatcagcag ccgtgatctc gcggagcact tcgcaaggat tacccgccgc aatcacgcgc
     3781 gctgggatgt cgtgggtgac aacactacct gctccgataa tcgtccccgc accaatcgtg
     3841 acgcctggta gtaccgtcac attggcagcg agccaacagc catccccgac tacaatcggt
     3901 ttagcaatac agccaccaag ttgtcgttca agcggatcaa aaagatggtt gctggtgtac
     3961 aaaccgactt tcgggccaaa caaaacgtga ttgccaatgg tcaccggcgc cccgtccaaa
     4021 atggtacagt cataattggc ataaaaatga tcgcctacgc ggatattccg accaaattca
     4081 cagtgaaagt ttgggttcac aaacggtttg aagccagttt ggcctaccaa tttcctaaac
     4141 aaggcattgc gtttggctgg atcgtgttca ttgttaagtg catcagtttt ggcagttgct
     4201 tcatcccgca cagccagtaa caaaggatcc atgtcgtcgt atggcttacc agttgccatg
     4261 aaagcaaatt tttcttctag attcattgcg ccacccctct ttattggctc aagtttacca
     4321 gacatttgcg cactgcgttg ataattgcca atatgttaag gtgtgcttat cggtacgcat
     4381 gaagtctaca aaaagccacc acttcttgaa gaaatggtgg cttgaaaaca atgacatcgc
     4441 ttctgcacac agaaccacgc ctgttttgtt acaaacagaa acatacagtt acagtcttca
     4501 tcgtcacaaa attctggcgt taggaaattt cagctacttc ctcggacttt atcagcttaa
     4561 tccatagact taatctcaag tgacattaac tcagatttta gcttttttaa atttgacata
     4621 gagataaatg taaagtcaag tcttccatct agagtagtga gaactatata agggttctgg
     4681 ggattgatta acctactcag ccccttacta gatagtttca aatcccgatt taacaaaagt
     4741 atcttggcaa tgactttgct tcttgctgcc ccttgccaaa gtcctccaac aaatggtgct
     4801 agataaaaag cgatcgtcgc cagtaaaatc aagataacta tgatgatact tattatctta
     4861 tccatttgta tttcctcttc cttttgcaca aatagactaa tttgaaatcg atctttgact
     4921 aagacaagaa aaagtgagca ctaccaaggt gttagttata ttgaacagtt gcgataggag
     4981 ctaaccgtct ttgtccaata ttaggctggg tgaatgtaat tagtgctgag acacaaggat
     5041 aatcctattg cagcgcctgc aacagttgta aatggattta atccagctgc ccctgctacc
     5101 gctcccccga tcgtggacac aatacaccca ctaggtttat tgcgtcgctt ggctcctcct
     5161 tggattaaga ccaaatcatg ctgttttaaa gtaatgccca cttctttact tatcattgca
     5221 tcccatctcc taagcattta atagctgacc caaccgctcc taagtttcca ccaactacgg
     5281 cgccgccgat tatcccaaaa ggaccaccag ctaggccagt aatcgttcct gatccaatac
     5341 cagccgtgat gccagtaaca aatgtagcag cacaatcaaa tttctttttc ccacctgaaa
     5401 cccctgacaa ctgaaaatcg tcgagctggc gataattata agacataatt ttcctttttt
     5461 cttcaaaaag caacaagtta ttttgtgtaa ggtcgatttt actgtcttta acatacatta
     5521 attatttgtg taaaatgcca aaatttttta aaggtaggaa atttccagtt taacgtcgtc
     5581 tttacacttt tattgttcag ttgcgcttta aaagtcaaaa attcttaacg tttaaatctc
     5641 cttgcttggt aaaaacttca attttttgca aaaaaaatcg tctcagcaat ttgagacaat
     5701 tttttcatat catcaactta cggcaagtca ttccccgccg caaagtaaat gtcataccat
     5761 tcctgtcggg tcaacgtgat gtccgcgcct tccgcacttt ccttgatatg ttcaggattc
     5821 atagagccga gaatcacttg cacaccgact ggatggcgta atagccaagc gactgcgatt
     5881 gcatttttat tggtatggta gtggtcagcg actttctgca gttcatcatt caacgcctta
     5941 aatttcgggc tatcgatgaa ggtaccttca aacatgccgt attggaatgg cgaccaggct
     6001 tgtaaggtca tgtgtttgcg ttgcaagtat ggtagcaggc tgccgtcatg atcgacagaa
     6061 gccgcgtcgg ccatgttggt gtgcatcccc gcattgacca taccagtgtg cgcaacggag
     6121 aactgaactt ggtcgatcag caaaggctgc cgaatgccgc tttcaagcaa cgcaatttgt
     6181 tcagggttaa agttggagac accaaaatgc cgaaccttgc cgctttgttc caatgcatca
     6241 aaggccgccg caacgtcatc gacttccatt aacggatctg gccggtgcag caagaccgaa
     6301 tcaaggtaat caacctgcaa ccgtttcaaa atgtgatcaa ccgctgacag taagtgatct
     6361 tttgaaaagt cgtaccgttt gccgaatacc aaactgccat gagagcgttt tgaatcaacg
     6421 acgatcccga ctttcgattg aatgaataac tgatcgcggg aaacgctggc ttgcttcaag
     6481 gcttcaccaa aaacttcttc ggatttgcct tggccataaa tgtcggccga gtcgataaag
     6541 ttgatgccgt cattgtacgc actatccagc acattggccg ctttgtcggg ggccagcaca
     6601 ttcatccgca tgatgcccaa ggccacactt gacgcctgcc aattggatcc gcctaatcga
     6661 acttgtttca taaacacaaa actcccttcg atacgtcatt tcaaattatg ttactgacga
     6721 caagttaagt gtagccccta aagtccactt gaggtcaagc caatattaga atttcaataa
     6781 aacagcttgc atggtgctga gctgcgcggt aggttaagct gtgtctgtta cttatttttt
     6841 cttagcagga taagcccata aaggaggccg tgattttgac agttaaagat aaagtggttg
     6901 taatcacagg tgcatcgagc gggattggcg cggcaacggt acaagtgttg gccgaggctg
     6961 gtgcaaaact agtcatcggt gcgcggcgca cagaacggtt ggctgaattg gcggccagct
     7021 ttacgaacgg tcaggtgctg tatcaacaaa ccgatgtgac cgaccagcag caagtgaaag
     7081 cgctgattga tttggcgttg gataagtttg gtcatgtgga tgttttgtat aacaacgctg
     7141 gcctgatgcc actttctgaa atggccgaac tcaaagtcaa cgaatgggaa cgtatgattg
     7201 acgtcaacat taaaggcgtc ttgtatggga tcgccgcggt tttaccgcct atgattgccc
     7261 aacacagtgg ccaaattatc acaacagact cagttgccgg tcacattgtt caccctggaa
     7321 ccgccgttta ctccggtacc aagtgggcta tccaggcgat catggacggc ctgcgacaag
     7381 aacaagcggc taatcatatt aaaacgacca tgatctcgcc cggtgccgtg aatactgagc
     7441 ttttcagcac aattaccgat cctaagcgcc gtgaagctgt tgaagccgat gaaaaaaaca
     7501 atggcctcag cgcctcggat gttgccaagg cagttttgta tgccattgat caaccggcca
     7561 atgttgccat caatgaagtg ctcttacggc cagtcacgca agaacgttaa ttttcgtcta
     7621 aaggagtgtg attgcatgtc gggttatcat tttttaaaac cgttcacctt caagcaccaa
     7681 accatcacgt tgaaaaatcg cattgtcatt ccgccgatga caacgcgcct gtcgtttgaa
     7741 gacggcactg tgacgcggga cgaaatcagg tattaccagc aacgggccgg tggcgtcggc
     7801 atgtttatta ccggtaccgc caacgtcaat gcgcttggca aaggattcga aggtgagcta
     7861 agtgtcgctg atgatcgatt catccccggt ttgagcaaac tcgccgctgc gatgaaaaca
     7921 ggcggcacca aggctatttt gcaaatcttc agcgctggcc gcatgagcaa tagcaagatt
     7981 ctgcgcggtg agcagccagt cagtgccagt gcggttgctg cgccacgggc gggttacgaa
     8041 acaccgcgcg cattgacatc ggcagaaatc gaggccacta ttcacgattt tggtcaggct
     8101 gtgcgccgcg ccatccttgc tggttttgat ggcatcgaac tgcatggtgc caacacctat
     8161 ctgatacagc aattctattc gccaaactct aatcgccgaa ccgatgaatg gggcggtgac
     8221 cgcgataagc ggatgcgttt tccgttggca gtcgttcatg aagcagaaaa agtgattgcc
     8281 acaattgctg accggccatt tttgttaggc taccgcattt cgccggaaga gttggaacag
     8341 cctggcatta ccttggatga taccttggcc ttaatcgaca ctttgaaaca aaccaagatt
     8401 gattacttgc acgtctccca aagtgacgtt tggcgaacct cattgcgcaa ccccgaggac
     8461 acagccatca tgaatgaaca aattcgtgac catgtcgccg gtgcttttcc agtgattgtg
     8521 gtcggtggca ttaaaacccc cgccgatgct gagaaagcgg cagaatcctt tgatttggtc
     8581 gcgattggtc acgaaatgat tcgcgagccg cactgggttc agaaggtctt agaccatgac
     8641 gaaaaggcga tccgttacca gatcgcccct gctgatcttg aagaacttgg cattgcgccg
     8701 accttcctcg attttatcga aagtatttcc ggtggggcaa aaggtgtccc gttaacaact
     8761 gcgcagtctg tgacatcaag caacgtgact caagattaat ctagcatttc aaatcatcgt
     8821 gcgagtcgag ctgtaaaaag ctcggctttt ttcttgccgt cttcaactta cgcgctggtg
     8881 cctgaagcta ccagtgattt ataagtttta aatcaaggtg tgatcatcac ctgctcacgc
     8941 tctgacttaa acgcgttcgc tggcgcagct cggctatgcg aaggacagtg acacagatgg
     9001 tccaaagccc agaccatctg tgtcactgcc acttcgctac gccgagctaa ccacgccagc
     9061 tcacgctctt gtcattttta acgggtcgac ccatttatca aactgcgctg ctgtgacgtc
     9121 gccgcttttg atggcggctg cttttaaatc gaggttttct tgctcagcca attgcgcgat
     9181 ggcggcactt ttttcgtagc cgatgtgggg tgcgagggcg gtgaccagca tgagcgaatg
     9241 atcaacgagt gctctcatat gcggtgcgtg gatggtcaag ccggcagcta atttttcagt
     9301 gaaactcgtg actgttttgg ttagtagatc agctgactct aaaaaggtac tgatgataac
     9361 cggcttgtag acgttcaatt caaaattgcc ttgtgacgcg gccaccgtga tcgtcgtatc
     9421 gttgcccatg actcgaacag cggccatggt tagcgcttcg gcctgtgtgg gattcacttt
     9481 gcccggcatg atggaactac caggctcatt ggccggaatg cgcaactcgc cgtatccagc
     9541 acgtggacca ctggcaagga agcgaatgtc attggcgatt ttaagcagat ccgccgctag
     9601 cgttttaatg gcaccatgaa caacgctaat ttctgagtgt gccgctaaag cagcaaactt
     9661 attggttttc gccgaaagtg gtaattgata aacatcgctc aatcggcccg ccacaatctt
     9721 gccaaaatta gggtcagcgt taagccccgt tccgactgct gttccgccaa tggctaagta
     9781 aaaaagattg ggctgaagct gctttaaagc aatctgatca tgctccatca tggccaccca
     9841 tccgctgatt tcttggccaa acgttagcgg cgttgcatcc tgtaaatgag ttcgaccgat
     9901 tttaacaaca cgagcgtaag tgacggcttt tgaatataaa acactgcaca gttggttgac
     9961 agcgtgcaac aactgattca ctgcaatagc cgccgtaata ttcatcacag ttggaaaagt
    10021 atcattggag ctttgactgt gattcacatc atcattcggt aagatcggca agtcggggtt
    10081 gagttttgca gcttggtggc taatgacttc gttcacattc atatttgttt gtgtgccaga
    10141 cccggtttga tagacatgca gtggaaaatc tttttgcagt ttttcgtctg gcaaggccaa
    10201 caaggcatcg actgctcgcg tgattaattg gccttttggt gccggtaaaa catcagcggc
    10261 cacatttgct cgcgctgccg cttttttgag ttgcagcaag gccctaatca ctggcatcgg
    10321 catcaatgga ccagcctgaa aattatggcg gctgcgctct gtttgcggtc cccacaaagc
    10381 gtttgccgga atttcaactg gtcctaatgt gtccgtttct gttcgatatt tgctcatgtt
    10441 tacctc
//
