## Fri May 2 18:48:20 2025 ## emapper-2.1.12 ## /home/m128030022/anaconda3/envs/eggnog/bin/emapper.py -i /home/m128030022/prbbiotics_cp/prokka_results/GCA_049191945.1/GCA_049191945.1.faa --temp_dir /home/m128030022/prbbiotics_cp/probiotics_new/databases/probiotics_DB/probiotics_db/GCA_049191945.1/2.eggNOGmapper --output_dir /home/m128030022/prbbiotics_cp/probiotics_new/databases/probiotics_DB/probiotics_db/GCA_049191945.1/2.eggNOGmapper --output eggNOG_out --override --cpu 14 -m diamond --sensmode fast ## #query seed_ortholog evalue score eggNOG_OGs max_annot_lvl COG_category Description Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction PFAMs GGPLMPOG_00001 547043.BIFPSEUDO_02422 5.76e-216 597.0 COG1175@1|root,COG1175@2|Bacteria,2GMTW@201174|Actinobacteria,4CZX2@85004|Bifidobacteriales 201174|Actinobacteria G Binding-protein-dependent transport system inner membrane component - - - ko:K02025 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 GGPLMPOG_00002 547043.BIFPSEUDO_04491 7.57e-209 581.0 COG0395@1|root,COG0395@2|Bacteria,2GJPZ@201174|Actinobacteria,4CYV5@85004|Bifidobacteriales 201174|Actinobacteria G ABC transporter permease - - - ko:K02026 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 GGPLMPOG_00003 547043.BIFPSEUDO_04308 3.91e-267 731.0 COG1940@1|root,COG1940@2|Bacteria,2GKMZ@201174|Actinobacteria,4CZUF@85004|Bifidobacteriales 201174|Actinobacteria GK ROK family - - - - - - - - - - - - Crp,HTH_24,ROK GGPLMPOG_00004 547043.BIFPSEUDO_04309 0.0 921.0 COG2211@1|root,COG2211@2|Bacteria,2HD4Y@201174|Actinobacteria,4CZRA@85004|Bifidobacteriales 201174|Actinobacteria G Psort location CytoplasmicMembrane, score 10.00 gph - - ko:K16209 - - - - ko00000,ko02000 2.A.2.2 - - MFS_2 GGPLMPOG_00005 547043.BIFPSEUDO_04310 0.0 2092.0 COG3250@1|root,COG3250@2|Bacteria,2GMAT@201174|Actinobacteria,4CYYS@85004|Bifidobacteriales 201174|Actinobacteria G Psort location Cytoplasmic, score 8.87 - - 3.2.1.23 ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 - R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 - - - Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Laminin_G_3 GGPLMPOG_00006 547043.BIFPSEUDO_04311 1.99e-175 488.0 COG0819@1|root,COG0819@2|Bacteria,2IGA8@201174|Actinobacteria,4CZRV@85004|Bifidobacteriales 201174|Actinobacteria K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino- 5-hydroxymethyl-2-methylpyrimidine (HMP) - - 3.5.99.2 ko:K03707 ko00730,ko01100,map00730,map01100 - R02133,R09993 RC00224,RC00652,RC02832 ko00000,ko00001,ko01000,ko03000 - - - TENA_THI-4 GGPLMPOG_00008 547043.BIFPSEUDO_04313 0.0 1488.0 COG3250@1|root,COG3250@2|Bacteria,2GMAT@201174|Actinobacteria,4CZH9@85004|Bifidobacteriales 201174|Actinobacteria G Belongs to the glycosyl hydrolase 2 family lacZ3 - - - - - - - - - - - Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N GGPLMPOG_00009 547043.BIFPSEUDO_04314 0.0 1259.0 COG0143@1|root,COG0143@2|Bacteria,2GK4S@201174|Actinobacteria,4CZ20@85004|Bifidobacteriales 201174|Actinobacteria J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG - 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g GGPLMPOG_00010 547043.BIFPSEUDO_04316 7.95e-139 392.0 2AU2N@1|root,31JNZ@2|Bacteria,2IJNI@201174|Actinobacteria,4D047@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_00011 547043.BIFPSEUDO_04318 1.04e-245 676.0 COG0313@1|root,COG0313@2|Bacteria,2GJ9Q@201174|Actinobacteria,4CZ03@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:1901360 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase GGPLMPOG_00012 1435051.BMOU_0563 9.63e-22 95.5 COG4124@1|root,COG4124@2|Bacteria,2GJ4D@201174|Actinobacteria,4CZ39@85004|Bifidobacteriales 201174|Actinobacteria G Glycosyl hydrolase family 26 - - 3.2.1.78 ko:K01218 ko00051,ko02024,map00051,map02024 - R01332 RC00467 ko00000,ko00001,ko01000 - GH26 - Glyco_hydro_26 GGPLMPOG_00013 547043.BIFPSEUDO_04322 8.68e-159 445.0 COG0586@1|root,COG0586@2|Bacteria,2GKGR@201174|Actinobacteria,4CZ7Y@85004|Bifidobacteriales 201174|Actinobacteria S SNARE associated Golgi protein dedA1 - - ko:K03975 - - - - ko00000 - - - SNARE_assoc GGPLMPOG_00015 547043.BIFPSEUDO_04325 2.41e-166 464.0 COG0637@1|root,COG0637@2|Bacteria,2GJNG@201174|Actinobacteria,4CYZV@85004|Bifidobacteriales 201174|Actinobacteria S HAD hydrolase, family IA, variant 3 - - - - - - - - - - - - HAD_2 GGPLMPOG_00016 547043.BIFPSEUDO_04326 6.08e-63 192.0 2BFF7@1|root,3298X@2|Bacteria,2IN83@201174|Actinobacteria,4D15M@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_00017 547043.BIFPSEUDO_04328 1.61e-146 414.0 COG0789@1|root,COG0789@2|Bacteria,2IQJ4@201174|Actinobacteria,4D0Q7@85004|Bifidobacteriales 201174|Actinobacteria K transcriptional regulator, MerR family hspR GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K13640 - - - - ko00000,ko03000 - - - MerR_1 GGPLMPOG_00018 547043.BIFPSEUDO_04329 2.09e-224 621.0 COG0484@1|root,COG0484@2|Bacteria,2GJKK@201174|Actinobacteria,4CZ68@85004|Bifidobacteriales 201174|Actinobacteria O DnaJ molecular chaperone homology domain dnaJ GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679 - ko:K03686,ko:K05516 - - - - ko00000,ko03029,ko03036,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG GGPLMPOG_00019 547043.BIFPSEUDO_04330 1.64e-106 313.0 COG0576@1|root,COG0576@2|Bacteria,2GP4F@201174|Actinobacteria,4CZJ6@85004|Bifidobacteriales 201174|Actinobacteria O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ grpE GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0017076,GO:0030234,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0044464,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0071496,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - ko:K03687 - - - - ko00000,ko03029,ko03110 - - - GrpE GGPLMPOG_00020 547043.BIFPSEUDO_04331 0.0 1159.0 COG0443@1|root,COG0443@2|Bacteria,2GJTY@201174|Actinobacteria,4CZDX@85004|Bifidobacteriales 201174|Actinobacteria O Heat shock 70 kDa protein dnaK GO:0000302,GO:0000303,GO:0000305,GO:0001968,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009893,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016310,GO:0019222,GO:0019538,GO:0019899,GO:0030112,GO:0030162,GO:0030312,GO:0030313,GO:0031323,GO:0031325,GO:0031975,GO:0031982,GO:0032268,GO:0032270,GO:0033554,GO:0034599,GO:0034614,GO:0035375,GO:0036211,GO:0040007,GO:0042221,GO:0042603,GO:0043170,GO:0043226,GO:0043227,GO:0043230,GO:0043388,GO:0043412,GO:0044044,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046677,GO:0046688,GO:0046777,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051098,GO:0051099,GO:0051101,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070613,GO:0070887,GO:0071450,GO:0071451,GO:0071704,GO:0071944,GO:0080090,GO:0097691,GO:1901564,GO:1901700,GO:1901701,GO:1903317,GO:1903319,GO:1903561,GO:2000677,GO:2000679 - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 GGPLMPOG_00021 547043.BIFPSEUDO_04332 4.46e-184 512.0 COG2013@1|root,COG2013@2|Bacteria,2IEKY@201174|Actinobacteria,4D0KV@85004|Bifidobacteriales 201174|Actinobacteria S Mitochondrial biogenesis AIM24 - - - - - - - - - - - - AIM24 GGPLMPOG_00022 401473.BDP_2181 0.0 1113.0 COG1785@1|root,COG1785@2|Bacteria,2GM8A@201174|Actinobacteria,4CYZF@85004|Bifidobacteriales 201174|Actinobacteria P Alkaline phosphatase homologues strK - 3.1.3.1,3.1.3.39 ko:K01077,ko:K04342 ko00521,ko00730,ko00790,ko01100,ko01130,ko02020,map00521,map00730,map00790,map01100,map01130,map02020 M00126 R02135,R02228,R04620 RC00017,RC00078 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 - - - Alk_phosphatase GGPLMPOG_00023 547043.BIFPSEUDO_04335 1.05e-176 497.0 COG0730@1|root,COG0730@2|Bacteria,2I5VT@201174|Actinobacteria,4CZFS@85004|Bifidobacteriales 201174|Actinobacteria S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE GGPLMPOG_00024 547043.BIFPSEUDO_04336 5.66e-200 558.0 COG3764@1|root,COG3764@2|Bacteria,2GNWT@201174|Actinobacteria,4CZMM@85004|Bifidobacteriales 201174|Actinobacteria M Sortase family - - 3.4.22.70 ko:K07284 - - - - ko00000,ko01000,ko01002,ko01011 - - - Sortase GGPLMPOG_00025 547043.BIFPSEUDO_04337 2.29e-246 679.0 COG4932@1|root,COG4932@2|Bacteria,2I9Z5@201174|Actinobacteria,4D07V@85004|Bifidobacteriales 201174|Actinobacteria M Cna protein B-type domain - - - - - - - - - - - - Cna_B GGPLMPOG_00026 401473.BDP_0277 2.03e-175 509.0 COG4932@1|root,COG4932@2|Bacteria,2H1EY@201174|Actinobacteria,4D00Q@85004|Bifidobacteriales 201174|Actinobacteria M LPXTG-motif cell wall anchor domain protein - - - - - - - - - - - - GramPos_pilinBB,Gram_pos_anchor GGPLMPOG_00027 547043.BIFPSEUDO_04339 0.0 2728.0 COG4932@1|root,COG5492@1|root,COG4932@2|Bacteria,COG5492@2|Bacteria,2HH2U@201174|Actinobacteria,4CZ5N@85004|Bifidobacteriales 201174|Actinobacteria M cell wall anchor domain protein - - - - - - - - - - - - Big_2,Gram_pos_anchor GGPLMPOG_00028 547043.BIFPSEUDO_04342 4.96e-247 678.0 COG1609@1|root,COG1609@2|Bacteria,2GJBJ@201174|Actinobacteria,4CZ1Y@85004|Bifidobacteriales 201174|Actinobacteria K Psort location Cytoplasmic, score - - - - - - - - - - - - LacI,Peripla_BP_3 GGPLMPOG_00029 547043.BIFPSEUDO_04343 3.83e-184 513.0 2AYHW@1|root,32WBP@2|Bacteria,2I9DQ@201174|Actinobacteria,4CYRI@85004|Bifidobacteriales 201174|Actinobacteria S TraX protein traX - - - - - - - - - - - TraX GGPLMPOG_00030 547043.BIFPSEUDO_04345 6.12e-186 517.0 COG1011@1|root,COG1011@2|Bacteria,2I2GN@201174|Actinobacteria,4CZF4@85004|Bifidobacteriales 201174|Actinobacteria S HAD-hyrolase-like - - - ko:K07025 - - - - ko00000 - - - HAD_2,Hydrolase GGPLMPOG_00031 547043.BIFPSEUDO_04346 0.0 1409.0 COG1523@1|root,COG1523@2|Bacteria,2I2GM@201174|Actinobacteria,4CYSS@85004|Bifidobacteriales 201174|Actinobacteria G Belongs to the glycosyl hydrolase 13 family apuB - 3.2.1.41,3.2.1.68 ko:K01200,ko:K01214 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02111,R09995,R11261 - ko00000,ko00001,ko00002,ko01000 - CBM48,GH13 - Alpha-amylase,CBM_48,CW_binding_1,DUF3372,PUD GGPLMPOG_00032 547043.BIFPSEUDO_04347 2.16e-208 577.0 COG3833@1|root,COG3833@2|Bacteria,2I2EZ@201174|Actinobacteria,4CZDE@85004|Bifidobacteriales 201174|Actinobacteria G Binding-protein-dependent transport system inner membrane component malG - - ko:K15772 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - - BPD_transp_1 GGPLMPOG_00033 547043.BIFPSEUDO_04348 0.0 905.0 COG1175@1|root,COG1175@2|Bacteria,2GJGB@201174|Actinobacteria,4CYZ8@85004|Bifidobacteriales 201174|Actinobacteria G Binding-protein-dependent transport system inner membrane component malC - - ko:K15771 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - - BPD_transp_1 GGPLMPOG_00034 547043.BIFPSEUDO_04349 1.16e-302 825.0 COG2182@1|root,COG2182@2|Bacteria,2GJ8S@201174|Actinobacteria,4CZ8G@85004|Bifidobacteriales 201174|Actinobacteria G Bacterial extracellular solute-binding protein malE - - ko:K15770 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - - SBP_bac_1,SBP_bac_8 GGPLMPOG_00035 547043.BIFPSEUDO_04350 0.0 1132.0 COG0366@1|root,COG0366@2|Bacteria,2GIV1@201174|Actinobacteria,4CZ7N@85004|Bifidobacteriales 201174|Actinobacteria G Alpha-amylase domain malL - 2.4.1.4,3.2.1.1,3.2.1.20,5.4.99.16 ko:K01187,ko:K05341,ko:K05343 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R01557,R01823,R02108,R02112,R06087,R06088,R11262 RC00028,RC00049,RC00077,RC01816 ko00000,ko00001,ko01000 - GH13,GH31 - Alpha-amylase,DUF3459 GGPLMPOG_00036 547043.BIFPSEUDO_04352 0.0 1452.0 COG1640@1|root,COG1640@2|Bacteria,2GM5Z@201174|Actinobacteria,4CZ0F@85004|Bifidobacteriales 201174|Actinobacteria G 4-alpha-glucanotransferase malQ GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.4.1.25 ko:K00705 ko00500,ko01100,map00500,map01100 - R05196 RC00049 ko00000,ko00001,ko01000 - GH77 - Glyco_hydro_77 GGPLMPOG_00037 1232443.BAIA02000032_gene1958 3.22e-18 77.8 2C5R4@1|root,30S72@2|Bacteria,1V578@1239|Firmicutes,24IJT@186801|Clostridia,26AY8@186813|unclassified Clostridiales 186801|Clostridia S Transposon-encoded protein TnpV - - - - - - - - - - - - TnpV GGPLMPOG_00038 547043.BIFPSEUDO_04353 1.16e-140 397.0 COG3340@1|root,COG3340@2|Bacteria,2GN35@201174|Actinobacteria,4D10R@85004|Bifidobacteriales 201174|Actinobacteria E Peptidase family S51 pepE GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 3.4.13.21 ko:K05995 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S51 GGPLMPOG_00039 547043.BIFPSEUDO_04356 2.34e-135 384.0 COG5578@1|root,COG5578@2|Bacteria,2IBKF@201174|Actinobacteria,4D0E0@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function, DUF624 - - - - - - - - - - - - DUF624 GGPLMPOG_00040 547043.BIFPSEUDO_04357 4.31e-194 539.0 COG0395@1|root,COG0395@2|Bacteria,2GJNN@201174|Actinobacteria,4CYZ9@85004|Bifidobacteriales 201174|Actinobacteria G ABC transporter permease - - - ko:K02026,ko:K10119 ko02010,map02010 M00196,M00207 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.28 - - BPD_transp_1 GGPLMPOG_00041 547043.BIFPSEUDO_04358 6.39e-198 549.0 COG1175@1|root,COG1175@2|Bacteria,2I330@201174|Actinobacteria,4CZJC@85004|Bifidobacteriales 201174|Actinobacteria G Binding-protein-dependent transport system inner membrane component msmF - - ko:K10118 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - BPD_transp_1 GGPLMPOG_00042 547043.BIFPSEUDO_04360 5.68e-234 644.0 COG1609@1|root,COG1609@2|Bacteria,2GJBJ@201174|Actinobacteria,4CZ1Y@85004|Bifidobacteriales 201174|Actinobacteria K Psort location Cytoplasmic, score - - - - - - - - - - - - LacI,Peripla_BP_3 GGPLMPOG_00043 547043.BIFPSEUDO_04361 2.16e-241 664.0 COG1609@1|root,COG1609@2|Bacteria,2GJBJ@201174|Actinobacteria,4D00W@85004|Bifidobacteriales 201174|Actinobacteria K Periplasmic binding protein-like domain - - - - - - - - - - - - LacI,Peripla_BP_3 GGPLMPOG_00044 547043.BIFPSEUDO_04362 0.0 911.0 COG1653@1|root,COG1653@2|Bacteria,2GWCY@201174|Actinobacteria,4CYWG@85004|Bifidobacteriales 201174|Actinobacteria G Bacterial extracellular solute-binding protein amyE - - ko:K10117 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - SBP_bac_8 GGPLMPOG_00045 547043.BIFPSEUDO_04363 0.0 1204.0 COG0366@1|root,COG0366@2|Bacteria,2GKS4@201174|Actinobacteria,4CZ1E@85004|Bifidobacteriales 201174|Actinobacteria G Alpha-amylase domain - - 3.2.1.20 ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 - GH31 - Alpha-amylase,DUF3459 GGPLMPOG_00046 547043.BIFPSEUDO_04364 0.0 889.0 COG1653@1|root,COG1653@2|Bacteria,2GWCY@201174|Actinobacteria,4CYWG@85004|Bifidobacteriales 201174|Actinobacteria G Bacterial extracellular solute-binding protein amyE - - ko:K10117 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - SBP_bac_8 GGPLMPOG_00047 547043.BIFPSEUDO_04365 8.44e-178 494.0 COG0406@1|root,COG0406@2|Bacteria,2GNRS@201174|Actinobacteria,4CZD2@85004|Bifidobacteriales 201174|Actinobacteria G Phosphoglycerate mutase family gpm2 GO:0003674,GO:0003824,GO:0003993,GO:0005488,GO:0005515,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0042802,GO:0042803,GO:0044237,GO:0046983 3.1.3.73 ko:K02226 ko00860,ko01100,map00860,map01100 M00122 R04594,R11173 RC00017 ko00000,ko00001,ko00002,ko01000 - - - His_Phos_1 GGPLMPOG_00048 547043.BIFPSEUDO_04366 4.34e-82 243.0 2B5DJ@1|root,31Y80@2|Bacteria,2IRRR@201174|Actinobacteria,4D1E6@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF4235) - - - - - - - - - - - - DUF4235 GGPLMPOG_00049 547043.BIFPSEUDO_04368 1.79e-180 503.0 COG0778@1|root,COG0778@2|Bacteria,2I65Z@201174|Actinobacteria,4CZ5R@85004|Bifidobacteriales 201174|Actinobacteria C Nitroreductase family nfrA - - - - - - - - - - - Nitroreductase GGPLMPOG_00050 547043.BIFPSEUDO_04369 9.41e-59 183.0 2B78R@1|root,320BB@2|Bacteria,2IQGT@201174|Actinobacteria,4D178@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_00051 547043.BIFPSEUDO_04161 5.59e-224 618.0 COG0524@1|root,COG0524@2|Bacteria,2I04R@201174|Actinobacteria,4CZIB@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway rbsK - 2.7.1.15 ko:K00852 ko00030,map00030 - R01051,R02750 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB GGPLMPOG_00052 547043.BIFPSEUDO_04160 0.0 896.0 COG0477@1|root,COG0477@2|Bacteria,2GJV6@201174|Actinobacteria,4CZH3@85004|Bifidobacteriales 201174|Actinobacteria EGP Major Facilitator Superfamily - - - ko:K08168 - M00704 - - ko00000,ko00002,ko01504,ko02000 2.A.1.3.16,2.A.1.3.22,2.A.1.3.6 - - MFS_1 GGPLMPOG_00053 547043.BIFPSEUDO_04159 2.62e-214 593.0 COG1957@1|root,COG1957@2|Bacteria,2GP6N@201174|Actinobacteria,4CZ0Y@85004|Bifidobacteriales 201174|Actinobacteria F Inosine-uridine preferring nucleoside hydrolase iunH2 - 3.2.2.1 ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 - R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 - - - IU_nuc_hydro GGPLMPOG_00054 547043.BIFPSEUDO_04158 5e-252 691.0 COG1609@1|root,COG1609@2|Bacteria,2GNVD@201174|Actinobacteria,4D05Q@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn _helix lactose operon repressor - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 GGPLMPOG_00055 547043.BIFPSEUDO_04157 2.33e-85 254.0 2BH71@1|root,32B89@2|Bacteria,2IIPG@201174|Actinobacteria,4D0XE@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_00056 566552.BIFCAT_00310 6.07e-292 797.0 COG1373@1|root,COG1373@2|Bacteria,2I96U@201174|Actinobacteria,4CZD7@85004|Bifidobacteriales 201174|Actinobacteria S AAA domain - - - ko:K07133 - - - - ko00000 - - - AAA_14,DUF4143 GGPLMPOG_00057 547043.BIFPSEUDO_04156 9.51e-258 705.0 COG1088@1|root,COG1088@2|Bacteria,2GNDU@201174|Actinobacteria,4CZZY@85004|Bifidobacteriales 201174|Actinobacteria M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily rfbB GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv3464 GDP_Man_Dehyd GGPLMPOG_00058 566552.BIFCAT_01375 7.66e-247 685.0 COG0675@1|root,COG0675@2|Bacteria,2GM6K@201174|Actinobacteria,4CZ11@85004|Bifidobacteriales 201174|Actinobacteria L Helix-turn-helix domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K07496 - - - - ko00000 - - - HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon GGPLMPOG_00059 216816.GS08_01775 2.71e-123 353.0 COG2452@1|root,COG2452@2|Bacteria,2IDNQ@201174|Actinobacteria,4CZVV@85004|Bifidobacteriales 201174|Actinobacteria L Resolvase, N terminal domain - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - ko:K07450 - - - - ko00000 - - - Resolvase GGPLMPOG_00060 398513.BBNG_00002 4.47e-40 143.0 COG1373@1|root,COG1373@2|Bacteria,2HJ52@201174|Actinobacteria,4D2TQ@85004|Bifidobacteriales 201174|Actinobacteria S Domain of unknown function (DUF4143) - - - ko:K07133 - - - - ko00000 - - - AAA_14,DUF4143 GGPLMPOG_00061 1680.BADO_1525 0.0 1080.0 COG1368@1|root,COG1368@2|Bacteria,2HVID@201174|Actinobacteria,4CZ6J@85004|Bifidobacteriales 201174|Actinobacteria M Psort location CytoplasmicMembrane, score 9.26 - - - - - - - - - - - - Sulfatase GGPLMPOG_00062 1680.BADO_1524 1.19e-263 726.0 COG1004@1|root,COG1004@2|Bacteria,2GJQB@201174|Actinobacteria,4CZ1N@85004|Bifidobacteriales 201174|Actinobacteria M UDP binding domain ugd - 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N GGPLMPOG_00063 78346.BRUM_1827 0.0 1202.0 COG1442@1|root,COG1442@2|Bacteria,2I2GU@201174|Actinobacteria,4D0KN@85004|Bifidobacteriales 201174|Actinobacteria M Glycosyl transferase family 8 - - - - - - - - - - - - DUF4422,Glyco_transf_8 GGPLMPOG_00064 216816.GS08_09795 1.82e-165 466.0 COG1682@1|root,COG1682@2|Bacteria,2GP5K@201174|Actinobacteria,4CZ73@85004|Bifidobacteriales 201174|Actinobacteria U Transport permease protein tagG - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane GGPLMPOG_00065 216816.GS08_09790 1.22e-210 593.0 COG1134@1|root,COG1134@2|Bacteria,2GIVF@201174|Actinobacteria,4CZ1B@85004|Bifidobacteriales 201174|Actinobacteria GM ABC transporter, ATP-binding protein - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,Wzt_C GGPLMPOG_00066 1120979.ATVB01000012_gene464 1.04e-33 138.0 COG1215@1|root,COG1215@2|Bacteria,2I2H4@201174|Actinobacteria,4D2Y4@85004|Bifidobacteriales 201174|Actinobacteria M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 GGPLMPOG_00067 1680.BADO_1516 0.0 1342.0 COG0463@1|root,COG1442@1|root,COG0463@2|Bacteria,COG1442@2|Bacteria,2I2GT@201174|Actinobacteria,4D2V5@85004|Bifidobacteriales 201174|Actinobacteria M Glycosyl transferase family 8 - - - - - - - - - - - - DUF4422,Glyco_transf_8,Glycos_transf_2 GGPLMPOG_00068 77635.BISU_0205 6.55e-15 78.6 2DGTK@1|root,2ZX8T@2|Bacteria,2I42E@201174|Actinobacteria,4D2WB@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_00069 1680.BADO_1515 1.63e-265 743.0 2E07M@1|root,32VVG@2|Bacteria,2ICM1@201174|Actinobacteria,4D036@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_00070 1680.BADO_1514 2.15e-145 422.0 COG3274@1|root,COG3274@2|Bacteria,2I2GS@201174|Actinobacteria,4D1N3@85004|Bifidobacteriales 201174|Actinobacteria I Acyltransferase family - - - - - - - - - - - - Acyl_transf_3 GGPLMPOG_00071 398513.BBNG_01824 1.44e-205 571.0 COG0463@1|root,COG0463@2|Bacteria,2I2GR@201174|Actinobacteria,4CZTN@85004|Bifidobacteriales 201174|Actinobacteria M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 GGPLMPOG_00072 702459.BBPR_0052 0.0 1213.0 COG2273@1|root,COG3533@1|root,COG3757@1|root,COG2273@2|Bacteria,COG3533@2|Bacteria,COG3757@2|Bacteria,2I2GQ@201174|Actinobacteria,4D08Z@85004|Bifidobacteriales 201174|Actinobacteria M Glycosyl hydrolases family 25 - - - - - - - - - - - - Glyco_hydro_25,RicinB_lectin_2,SLH GGPLMPOG_00073 547043.BIFPSEUDO_04141 0.0 894.0 COG1373@1|root,COG1373@2|Bacteria,2HVUN@201174|Actinobacteria,4CZHJ@85004|Bifidobacteriales 201174|Actinobacteria S AAA domain - - - ko:K07133 - - - - ko00000 - - - AAA_14,DUF4143 GGPLMPOG_00074 566552.BIFCAT_01951 2.35e-86 264.0 2B5Q5@1|root,31YJP@2|Bacteria,2IPRN@201174|Actinobacteria,4D144@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_00075 547043.BIFPSEUDO_04138 0.0 918.0 COG2755@1|root,COG2755@2|Bacteria,2I93Y@201174|Actinobacteria,4D07C@85004|Bifidobacteriales 201174|Actinobacteria E Carbohydrate esterase, sialic acid-specific acetylesterase - - 3.1.1.53 ko:K05970 - - - - ko00000,ko01000 - - - SASA GGPLMPOG_00076 566552.BIFCAT_01949 5.57e-64 197.0 2B0X3@1|root,31T9V@2|Bacteria,2GS0B@201174|Actinobacteria,4D1HX@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_00077 77635.BISU_2273 4.2e-12 61.6 2B3KJ@1|root,31W9X@2|Bacteria,2GWXF@201174|Actinobacteria,4D1NA@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_00079 1680.BADO_1497 1.07e-129 378.0 COG3598@1|root,COG3598@2|Bacteria 2|Bacteria L Psort location Cytoplasmic, score - - - ko:K06919 - - - - ko00000 - - - AAA_25,D5_N,Pox_D5,PriCT_2,Prim-Pol,VirE GGPLMPOG_00080 1235790.C805_01415 1.31e-123 351.0 COG4734@1|root,COG4734@2|Bacteria,1TNY7@1239|Firmicutes,249HA@186801|Clostridia,25WNI@186806|Eubacteriaceae 186801|Clostridia S Antirestriction protein (ArdA) - - - - - - - - - - - - ArdA GGPLMPOG_00081 742765.HMPREF9457_01141 1.49e-112 323.0 COG4734@1|root,COG4734@2|Bacteria,1UX6H@1239|Firmicutes,24AM6@186801|Clostridia 186801|Clostridia S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - ArdA GGPLMPOG_00082 742765.HMPREF9457_02034 4.73e-66 200.0 2AJ8P@1|root,319TK@2|Bacteria,1V9F5@1239|Firmicutes,24KKK@186801|Clostridia 186801|Clostridia S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - - GGPLMPOG_00083 1235790.C805_01419 3.41e-41 135.0 2C9BX@1|root,32RP2@2|Bacteria,1VANR@1239|Firmicutes,24N4I@186801|Clostridia,25X23@186806|Eubacteriaceae 186801|Clostridia S Psort location CytoplasmicMembrane, score - - - - - - - - - - - - - GGPLMPOG_00084 658659.HMPREF0983_03987 4.78e-22 85.5 2E3NJ@1|root,32YKN@2|Bacteria,1VIHR@1239|Firmicutes,3VRKR@526524|Erysipelotrichia 526524|Erysipelotrichia S Protein of unknown function (DUF3789) - - - - - - - - - - - - DUF3789 GGPLMPOG_00085 1121115.AXVN01000064_gene4031 7.61e-261 716.0 COG2946@1|root,COG2946@2|Bacteria,1UHNT@1239|Firmicutes,24ZUP@186801|Clostridia,3XZ7X@572511|Blautia 186801|Clostridia L Psort location Cytoplasmic, score 8.87 - - - ko:K07467 - - - - ko00000 - - - HTH_3,HTH_31,Rep_trans GGPLMPOG_00086 1499683.CCFF01000017_gene2492 2.28e-52 169.0 29N5Q@1|root,3093K@2|Bacteria,1V42V@1239|Firmicutes,24TG9@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - GGPLMPOG_00087 658659.HMPREF0983_03911 0.0 902.0 COG1674@1|root,COG1674@2|Bacteria,1TPHE@1239|Firmicutes,3VNUV@526524|Erysipelotrichia 526524|Erysipelotrichia D Ftsk spoiiie family protein - - - - - - - - - - - - FtsK_SpoIIIE GGPLMPOG_00088 658659.HMPREF0983_03910 4.33e-69 209.0 2D4CF@1|root,32TGR@2|Bacteria,1VCXI@1239|Firmicutes,3VTRS@526524|Erysipelotrichia 526524|Erysipelotrichia - - - - - - - - - - - - - - - GGPLMPOG_00089 658659.HMPREF0983_03909 1.25e-83 248.0 COG1476@1|root,COG1476@2|Bacteria,1V624@1239|Firmicutes,3VTJP@526524|Erysipelotrichia 526524|Erysipelotrichia K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - - GGPLMPOG_00090 742765.HMPREF9457_02046 1.24e-86 254.0 28NIV@1|root,2ZBK5@2|Bacteria,1V1U5@1239|Firmicutes,24FW5@186801|Clostridia,27WXP@189330|Dorea 186801|Clostridia S Bacterial protein of unknown function (DUF961) - - - - - - - - - - - - DUF961 GGPLMPOG_00091 1504823.CCMM01000013_gene2508 3.85e-72 216.0 2BXTH@1|root,2ZZ52@2|Bacteria 2|Bacteria S COG NOG10998 non supervised orthologous group - - - - - - - - - - - - DUF961 GGPLMPOG_00092 411470.RUMGNA_02413 1.19e-44 144.0 2DVIT@1|root,32UZI@2|Bacteria,1VDW7@1239|Firmicutes,250TP@186801|Clostridia 186801|Clostridia S Psort location Extracellular, score 8.82 - - - - - - - - - - - - - GGPLMPOG_00093 999413.HMPREF1094_00371 0.0 1904.0 COG4932@1|root,COG4932@2|Bacteria,1TS9Q@1239|Firmicutes,3VPKA@526524|Erysipelotrichia 526524|Erysipelotrichia M Psort location Cellwall, score - - - - - - - - - - - - Gram_pos_anchor GGPLMPOG_00094 762211.BSTEL_1785 4.53e-18 77.4 29RY3@1|root,30D2D@2|Bacteria,2GWAQ@201174|Actinobacteria,4D1M1@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - HTH_17 GGPLMPOG_00095 1680.BADO_1495 3.56e-53 180.0 COG0582@1|root,COG0582@2|Bacteria,2GISN@201174|Actinobacteria,4D0EV@85004|Bifidobacteriales 201174|Actinobacteria L Phage integrase, N-terminal SAM-like domain intA - - - - - - - - - - - Phage_int_SAM_3,Phage_integrase GGPLMPOG_00096 1121864.OMO_01639 1.56e-60 189.0 COG1191@1|root,COG1191@2|Bacteria,1V1GF@1239|Firmicutes 1239|Firmicutes K Psort location Cytoplasmic, score XK26_06155 - - - - - - - - - - - Sigma70_r4 GGPLMPOG_00097 1121864.OMO_01639 1.04e-40 137.0 COG1191@1|root,COG1191@2|Bacteria,1V1GF@1239|Firmicutes 1239|Firmicutes K Psort location Cytoplasmic, score XK26_06155 - - - - - - - - - - - Sigma70_r4 GGPLMPOG_00098 411462.DORLON_02667 0.0 1275.0 COG0480@1|root,COG0480@2|Bacteria,1TPQH@1239|Firmicutes,247X4@186801|Clostridia,27V24@189330|Dorea 186801|Clostridia J Elongation factor G, domain IV - - - ko:K18220 - - - - br01600,ko00000,ko01504 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU GGPLMPOG_00099 1121864.OMO_01641 4.04e-86 253.0 2C5R4@1|root,2ZC1N@2|Bacteria,1V292@1239|Firmicutes 1239|Firmicutes S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - TnpV GGPLMPOG_00100 1680.BADO_1495 2.68e-234 652.0 COG0582@1|root,COG0582@2|Bacteria,2GISN@201174|Actinobacteria,4D0EV@85004|Bifidobacteriales 201174|Actinobacteria L Phage integrase, N-terminal SAM-like domain intA - - - - - - - - - - - Phage_int_SAM_3,Phage_integrase GGPLMPOG_00103 566552.BIFCAT_01938 0.0 902.0 COG1653@1|root,COG1653@2|Bacteria,2GJIP@201174|Actinobacteria,4CYRE@85004|Bifidobacteriales 201174|Actinobacteria G Bacterial extracellular solute-binding protein - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_1,SBP_bac_8 GGPLMPOG_00104 566552.BIFCAT_01939 1.35e-237 654.0 COG1609@1|root,COG1609@2|Bacteria,2GJDS@201174|Actinobacteria,4CZR6@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn _helix lactose operon repressor - - - - - - - - - - - - LacI,Peripla_BP_1,Peripla_BP_3 GGPLMPOG_00105 1435051.BMOU_2105 0.0 1120.0 COG0366@1|root,COG0366@2|Bacteria,2GKS4@201174|Actinobacteria,4CZT7@85004|Bifidobacteriales 201174|Actinobacteria G Alpha amylase, catalytic domain protein - - 3.2.1.10 ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00801,R01718,R01791,R06199 RC00028,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,DUF3459,Malt_amylase_C GGPLMPOG_00107 547043.BIFPSEUDO_04306 7.98e-300 818.0 COG1653@1|root,COG1653@2|Bacteria,2GJIP@201174|Actinobacteria,4CZ88@85004|Bifidobacteriales 201174|Actinobacteria G Bacterial extracellular solute-binding protein - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_1 GGPLMPOG_00108 547043.BIFPSEUDO_04305 3.13e-195 544.0 COG1175@1|root,COG1175@2|Bacteria,2GMTW@201174|Actinobacteria,4CZX2@85004|Bifidobacteriales 201174|Actinobacteria G Binding-protein-dependent transport system inner membrane component - - - ko:K02025 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 GGPLMPOG_00109 547043.BIFPSEUDO_04304 1.03e-216 599.0 COG0395@1|root,COG0395@2|Bacteria,2GJPZ@201174|Actinobacteria,4CYV5@85004|Bifidobacteriales 201174|Actinobacteria G ABC transporter permease - - - ko:K02026 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 GGPLMPOG_00110 547043.BIFPSEUDO_04303 4.41e-218 602.0 COG1940@1|root,COG1940@2|Bacteria,2GZ27@201174|Actinobacteria,4CZII@85004|Bifidobacteriales 201174|Actinobacteria GK ROK family - - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - ROK GGPLMPOG_00111 547043.BIFPSEUDO_04302 0.0 1350.0 COG3525@1|root,COG3525@2|Bacteria,2HZCI@201174|Actinobacteria,4CZS1@85004|Bifidobacteriales 201174|Actinobacteria G Glycosyl hydrolase family 20, domain 2 - - - - - - - - - - - - Glyco_hydro_20,Glyco_hydro_20b GGPLMPOG_00112 547043.BIFPSEUDO_04300 9.44e-193 535.0 COG0363@1|root,COG0363@2|Bacteria,2GK7F@201174|Actinobacteria,4CYYE@85004|Bifidobacteriales 201174|Actinobacteria G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion nagB - 3.5.99.6 ko:K02564 ko00520,ko01100,map00520,map01100 - R00765 RC00163 ko00000,ko00001,ko01000 - - - Glucosamine_iso GGPLMPOG_00113 547043.BIFPSEUDO_04298 0.0 876.0 COG1820@1|root,COG1820@2|Bacteria,2GK1E@201174|Actinobacteria,4CZKB@85004|Bifidobacteriales 201174|Actinobacteria G Amidohydrolase family nagA - 3.5.1.25 ko:K01443 ko00520,ko01130,map00520,map01130 - R02059 RC00166,RC00300 ko00000,ko00001,ko01000 - - - Amidohydro_1 GGPLMPOG_00114 547043.BIFPSEUDO_04297 4.34e-243 668.0 COG1609@1|root,COG1609@2|Bacteria,2H5ZG@201174|Actinobacteria,4CZ8A@85004|Bifidobacteriales 201174|Actinobacteria K Transcriptional regulator, LacI family - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 GGPLMPOG_00115 547043.BIFPSEUDO_04296 0.0 1543.0 COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4D0M7@85004|Bifidobacteriales 201174|Actinobacteria T Diguanylate cyclase, GGDEF domain - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_4,PAS_9 GGPLMPOG_00116 547043.BIFPSEUDO_04295 0.0 865.0 COG3979@1|root,COG3979@2|Bacteria,2I2XD@201174|Actinobacteria,4CZW2@85004|Bifidobacteriales 201174|Actinobacteria S Carbohydrate binding domain - - 3.2.1.14 ko:K01183 ko00520,ko01100,map00520,map01100 - R01206,R02334 RC00467 ko00000,ko00001,ko01000 - GH18 - Glyco_hydro_18 GGPLMPOG_00117 547043.BIFPSEUDO_04294 0.0 1493.0 COG1215@1|root,COG1215@2|Bacteria,2GN8M@201174|Actinobacteria,4D042@85004|Bifidobacteriales 201174|Actinobacteria M probably involved in cell wall - - - - - - - - - - - - EAL,Glyco_trans_2_3 GGPLMPOG_00118 547043.BIFPSEUDO_04293 6.84e-243 668.0 COG1609@1|root,COG1609@2|Bacteria,2GJDS@201174|Actinobacteria,4CZR6@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn _helix lactose operon repressor - - - - - - - - - - - - LacI,Peripla_BP_3 GGPLMPOG_00119 547043.BIFPSEUDO_04291 0.0 883.0 COG1653@1|root,COG1653@2|Bacteria,2GP9H@201174|Actinobacteria,4CYX5@85004|Bifidobacteriales 201174|Actinobacteria G Bacterial extracellular solute-binding protein - - - ko:K10117 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - SBP_bac_1,SBP_bac_8 GGPLMPOG_00120 547043.BIFPSEUDO_04290 4.05e-215 595.0 COG1175@1|root,COG1175@2|Bacteria,2GJZD@201174|Actinobacteria,4CYTH@85004|Bifidobacteriales 201174|Actinobacteria G Binding-protein-dependent transport system inner membrane component - - - ko:K02025,ko:K10118 ko02010,map02010 M00196,M00207 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.28 - - BPD_transp_1 GGPLMPOG_00121 547043.BIFPSEUDO_04289 7.99e-196 544.0 COG0395@1|root,COG0395@2|Bacteria,2GJNN@201174|Actinobacteria,4CYRC@85004|Bifidobacteriales 201174|Actinobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02026,ko:K10119 ko02010,map02010 M00196,M00207 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.28 - - BPD_transp_1 GGPLMPOG_00122 566552.BIFCAT_00237 1.03e-294 807.0 COG1215@1|root,COG4030@1|root,COG1215@2|Bacteria,COG4030@2|Bacteria,2GJFD@201174|Actinobacteria,4CZ06@85004|Bifidobacteriales 201174|Actinobacteria M Protein of unknown function (DUF2961) - - - - - - - - - - - - DUF2961 GGPLMPOG_00123 547043.BIFPSEUDO_04286 3.18e-197 546.0 COG0657@1|root,COG0657@2|Bacteria,2HZCA@201174|Actinobacteria,4CZQE@85004|Bifidobacteriales 201174|Actinobacteria I alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_3,Peptidase_S9 GGPLMPOG_00125 547043.BIFPSEUDO_04284 7.33e-272 743.0 COG0657@1|root,COG0657@2|Bacteria,2HGIX@201174|Actinobacteria,4CZUK@85004|Bifidobacteriales 201174|Actinobacteria I Hydrolase, alpha beta domain protein - - - - - - - - - - - - Abhydrolase_3 GGPLMPOG_00126 547043.BIFPSEUDO_04282 0.0 1219.0 COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4D028@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran GGPLMPOG_00127 547043.BIFPSEUDO_04281 0.0 1135.0 COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4CZ32@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran GGPLMPOG_00128 547043.BIFPSEUDO_04280 6.8e-162 454.0 2AU3T@1|root,31JQA@2|Bacteria,2IJQ7@201174|Actinobacteria,4D0VX@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_00129 547043.BIFPSEUDO_04279 0.0 1654.0 COG3345@1|root,COG3345@2|Bacteria,2GJJ1@201174|Actinobacteria,4CZDM@85004|Bifidobacteriales 201174|Actinobacteria G Psort location Cytoplasmic, score 8.87 - - 3.2.1.22 ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 - R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 - - - Glyco_hydro_36N,Melibiase GGPLMPOG_00130 547043.BIFPSEUDO_04278 9.3e-291 794.0 COG1609@1|root,COG1609@2|Bacteria,2GJ5Q@201174|Actinobacteria,4D041@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn _helix lactose operon repressor - - - - - - - - - - - - LacI,Peripla_BP_3 GGPLMPOG_00131 78344.BIGA_1176 1.08e-292 804.0 COG1501@1|root,COG1501@2|Bacteria,2I4RN@201174|Actinobacteria,4D07N@85004|Bifidobacteriales 201174|Actinobacteria G Alpha galactosidase A - - - - - - - - - - - - Melibiase_2 GGPLMPOG_00132 547043.BIFPSEUDO_04275 0.0 1612.0 COG3534@1|root,COG3534@2|Bacteria,2HZF4@201174|Actinobacteria,4D06Z@85004|Bifidobacteriales 201174|Actinobacteria G Alpha-L-arabinofuranosidase C-terminus - - - - - - - - - - - - Alpha-L-AF_C GGPLMPOG_00133 547043.BIFPSEUDO_04274 8.42e-236 647.0 COG0084@1|root,COG0084@2|Bacteria,2GMJJ@201174|Actinobacteria,4CYZI@85004|Bifidobacteriales 201174|Actinobacteria L TatD related DNase tatD GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase GGPLMPOG_00134 547043.BIFPSEUDO_04273 0.0 1424.0 COG3158@1|root,COG3158@2|Bacteria,2GMPQ@201174|Actinobacteria,4CZM3@85004|Bifidobacteriales 201174|Actinobacteria P Transport of potassium into the cell kup - - ko:K03549 - - - - ko00000,ko02000 2.A.72 - - K_trans GGPLMPOG_00135 547043.BIFPSEUDO_04271 5.56e-213 588.0 COG0121@1|root,COG0121@2|Bacteria,2IBFV@201174|Actinobacteria,4CYX2@85004|Bifidobacteriales 201174|Actinobacteria S Glutamine amidotransferase domain - - - - - - - - - - - - GATase_6 GGPLMPOG_00136 547043.BIFPSEUDO_04270 6.41e-192 532.0 COG2206@1|root,COG2206@2|Bacteria,2GNQR@201174|Actinobacteria,4CYT9@85004|Bifidobacteriales 201174|Actinobacteria T HD domain - - - ko:K06950 - - - - ko00000 - - - HD GGPLMPOG_00137 547043.BIFPSEUDO_04269 2.43e-231 643.0 COG1136@1|root,COG1136@2|Bacteria,2GNFW@201174|Actinobacteria,4CZAW@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran GGPLMPOG_00138 566552.BIFCAT_00255 2.73e-301 823.0 COG0577@1|root,COG0577@2|Bacteria,2GMGJ@201174|Actinobacteria,4CZBN@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter permease - - - - - - - - - - - - FtsX,MacB_PCD GGPLMPOG_00139 566552.BIFCAT_00256 0.0 1298.0 COG5617@1|root,COG5617@2|Bacteria,2HKW0@201174|Actinobacteria,4D00J@85004|Bifidobacteriales 201174|Actinobacteria S Psort location CytoplasmicMembrane, score 9.99 - - - - - - - - - - - - - GGPLMPOG_00142 78346.BRUM_0422 1.46e-69 213.0 2C5TS@1|root,2ZX0Y@2|Bacteria,2IT81@201174|Actinobacteria,4D1BF@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - Peptidase_M78 GGPLMPOG_00149 1435051.BMOU_0741 1.74e-90 270.0 COG0270@1|root,COG0270@2|Bacteria 2|Bacteria L DNA (cytosine-5-)-methyltransferase activity dcm - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase GGPLMPOG_00150 742722.HMPREF9463_00216 1.06e-38 132.0 COG0270@1|root,COG0270@2|Bacteria,2IF94@201174|Actinobacteria,4CVQX@84998|Coriobacteriia 84998|Coriobacteriia H C-5 cytosine-specific DNA methylase - - - - - - - - - - - - DNA_methylase GGPLMPOG_00156 78346.BRUM_0411 3.36e-126 359.0 2CD0S@1|root,3060X@2|Bacteria,2GRR9@201174|Actinobacteria,4D1K0@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_00157 1435051.BMOU_0794 1.15e-99 303.0 COG3723@1|root,COG3723@2|Bacteria,2II5R@201174|Actinobacteria 201174|Actinobacteria L RecT family - - - - - - - - - - - - RecT GGPLMPOG_00159 78346.BRUM_0409 3.6e-79 239.0 COG0629@1|root,COG0629@2|Bacteria,2GMM3@201174|Actinobacteria,4D26X@85004|Bifidobacteriales 201174|Actinobacteria L Single-strand binding protein family ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB GGPLMPOG_00161 158787.BSCA_0758 2.72e-37 132.0 COG4570@1|root,COG4570@2|Bacteria,2GQT6@201174|Actinobacteria,4D1DZ@85004|Bifidobacteriales 201174|Actinobacteria L Endodeoxyribonuclease RusA - - - - - - - - - - - - RusA GGPLMPOG_00165 78346.BRUM_0403 1.17e-21 84.7 2B4W2@1|root,31XNR@2|Bacteria,2GZAZ@201174|Actinobacteria,4D1QA@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_00167 1680.BADO_1253 1.33e-40 138.0 2EI4V@1|root,33BW7@2|Bacteria,2HZTR@201174|Actinobacteria,4D1QD@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknwon function (DUF3310) - - - - - - - - - - - - DUF3310 GGPLMPOG_00174 1680.BADO_1261 7.82e-105 304.0 2CK7Q@1|root,2ZMHH@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - GGPLMPOG_00177 1680.BADO_1259 2.01e-28 105.0 2AD62@1|root,312US@2|Bacteria,2HCXF@201174|Actinobacteria,4D2KS@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_00178 104623.Ser39006_02605 6.13e-70 218.0 COG0500@1|root,COG2226@2|Bacteria,1QUBD@1224|Proteobacteria,1T1S4@1236|Gammaproteobacteria,400AN@613|Serratia 1236|Gammaproteobacteria Q methyltransferase - - - - - - - - - - - - Methyltransf_11 GGPLMPOG_00179 1394176.AWUO01000011_gene389 1.62e-50 166.0 2EECP@1|root,3386X@2|Bacteria,2HD3K@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_00183 78346.BRUM_0405 4.12e-126 366.0 2DRSV@1|root,33CWS@2|Bacteria,2GRW4@201174|Actinobacteria,4D1IT@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_00187 1121934.AUDX01000004_gene2520 7.65e-34 122.0 COG0756@1|root,COG0756@2|Bacteria,2IHYY@201174|Actinobacteria,4FNR6@85023|Microbacteriaceae 201174|Actinobacteria F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA dut GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase GGPLMPOG_00193 31757.VG66_BPML5 3.15e-15 79.3 4QAIK@10239|Viruses,4QUPH@35237|dsDNA viruses no RNA stage,4QPEB@28883|Caudovirales,4QKNC@10699|Siphoviridae 10699|Siphoviridae S hydrolase activity - - - - - - - - - - - - - GGPLMPOG_00195 1394176.AWUO01000014_gene645 5.25e-75 238.0 COG4974@1|root,COG4974@2|Bacteria,2ID5W@201174|Actinobacteria 201174|Actinobacteria L Belongs to the 'phage' integrase family - - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase GGPLMPOG_00196 1394176.AWUO01000014_gene644 4.15e-80 250.0 2BWS4@1|root,32XQ0@2|Bacteria,2GR3P@201174|Actinobacteria,4D1S1@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_00211 1692.BMAGN_1438 5.3e-45 148.0 COG1403@1|root,COG1403@2|Bacteria,2HZZX@201174|Actinobacteria,4D2FJ@85004|Bifidobacteriales 201174|Actinobacteria V HNH endonuclease - - - - - - - - - - - - - GGPLMPOG_00214 1692.BMAGN_1441 1.6e-227 653.0 COG4626@1|root,COG4626@2|Bacteria,2GNSB@201174|Actinobacteria,4D0MR@85004|Bifidobacteriales 201174|Actinobacteria S Terminase - - - - - - - - - - - - Terminase_1 GGPLMPOG_00215 1692.BMAGN_1442 1.39e-171 503.0 29W7F@1|root,30HSN@2|Bacteria,2IQFQ@201174|Actinobacteria,4CZHR@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - Phage_prot_Gp6 GGPLMPOG_00216 1692.BMAGN_1443 9.61e-82 260.0 2AYWB@1|root,307JP@2|Bacteria,2IIGR@201174|Actinobacteria,4D0ZW@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_00218 1692.BMAGN_1445 1.92e-53 175.0 2AVHC@1|root,31M9S@2|Bacteria,2IMWD@201174|Actinobacteria,4D13V@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_00219 1692.BMAGN_1446 1.59e-95 295.0 2B56X@1|root,31Y0T@2|Bacteria,2HZKE@201174|Actinobacteria,4D0T6@85004|Bifidobacteriales 201174|Actinobacteria S Phage major capsid protein E - - - - - - - - - - - - Phage_cap_E GGPLMPOG_00220 1692.BMAGN_1447 8.05e-45 150.0 2B1US@1|root,31UAS@2|Bacteria,2GTRB@201174|Actinobacteria,4D1FX@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_00227 35760.BCHO_0831 3.41e-152 525.0 COG0840@1|root,COG1196@1|root,COG1511@1|root,COG5412@1|root,COG0840@2|Bacteria,COG1196@2|Bacteria,COG1511@2|Bacteria,COG5412@2|Bacteria,2HZEA@201174|Actinobacteria,4D021@85004|Bifidobacteriales 201174|Actinobacteria DNT domain protein - - - - - - - - - - - - - GGPLMPOG_00229 1680.BADO_1230 2.49e-177 516.0 2BPU9@1|root,32IMR@2|Bacteria,2IG69@201174|Actinobacteria,4D0RH@85004|Bifidobacteriales 201174|Actinobacteria S Psort location Cytoplasmic, score - - - - - - - - - - - - Sipho_Gp37 GGPLMPOG_00232 547043.BIFPSEUDO_03182 1.99e-109 314.0 2AWVC@1|root,31NSP@2|Bacteria,2IPYB@201174|Actinobacteria,4D15U@85004|Bifidobacteriales 201174|Actinobacteria K Cro/C1-type HTH DNA-binding domain - - - - - - - - - - - - HTH_3 GGPLMPOG_00233 547043.BIFPSEUDO_03183 0.0 1852.0 COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4CZ1I@85004|Bifidobacteriales 201174|Actinobacteria P Cation transporter/ATPase, N-terminus pacL2 - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 GGPLMPOG_00234 547043.BIFPSEUDO_03185 0.0 2097.0 COG3250@1|root,COG3250@2|Bacteria,2GMAT@201174|Actinobacteria,4CYYS@85004|Bifidobacteriales 201174|Actinobacteria G Psort location Cytoplasmic, score 8.87 - - 3.2.1.23 ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 - R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 - - - Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Laminin_G_3 GGPLMPOG_00235 547043.BIFPSEUDO_03187 3.34e-193 538.0 COG3247@1|root,COG3247@2|Bacteria,2H3AT@201174|Actinobacteria,4D00R@85004|Bifidobacteriales 201174|Actinobacteria S Short repeat of unknown function (DUF308) - - - - - - - - - - - - DUF308 GGPLMPOG_00236 547043.BIFPSEUDO_03188 2.75e-66 201.0 2BCF9@1|root,3260W@2|Bacteria,2HBC0@201174|Actinobacteria,4D2ID@85004|Bifidobacteriales 201174|Actinobacteria S Antitoxin component of a toxin-antitoxin (TA) module - - - - - - - - - - - - PhdYeFM_antitox GGPLMPOG_00237 547043.BIFPSEUDO_03189 1.44e-72 218.0 COG2026@1|root,COG2026@2|Bacteria,2GRMT@201174|Actinobacteria,4D1F9@85004|Bifidobacteriales 201174|Actinobacteria DJ Addiction module toxin, RelE StbE family - - - ko:K06218 - - - - ko00000,ko02048 - - - ParE_toxin GGPLMPOG_00238 547043.BIFPSEUDO_03986 6.49e-19 79.3 2B4NV@1|root,31XF4@2|Bacteria,2GYXI@201174|Actinobacteria,4D1TF@85004|Bifidobacteriales 201174|Actinobacteria S Psort location Extracellular, score 8.82 - - - - - - - - - - - - - GGPLMPOG_00239 547043.BIFPSEUDO_03192 2.35e-295 808.0 COG0477@1|root,COG2814@2|Bacteria,2GJU2@201174|Actinobacteria,4CZVY@85004|Bifidobacteriales 201174|Actinobacteria EGP Transmembrane secretion effector - - - - - - - - - - - - MFS_1,Sugar_tr GGPLMPOG_00240 547043.BIFPSEUDO_03193 1.48e-223 618.0 COG0566@1|root,COG0566@2|Bacteria,2GJMR@201174|Actinobacteria,4CZB1@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family rlmB GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 ko:K03218 - - - - ko00000,ko01000,ko03009 - - - SpoU_methylase,SpoU_sub_bind GGPLMPOG_00241 547043.BIFPSEUDO_03194 0.0 933.0 COG0515@1|root,COG0515@2|Bacteria,2I2F0@201174|Actinobacteria,4CZ2E@85004|Bifidobacteriales 201174|Actinobacteria KLT Domain of unknown function (DUF4032) - - - - - - - - - - - - DUF4032,Kdo GGPLMPOG_00242 547043.BIFPSEUDO_03195 1.26e-268 735.0 COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4CYU6@85004|Bifidobacteriales 201174|Actinobacteria E Belongs to the ABC transporter superfamily ugpC - - ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1 - - ABC_tran,TOBE,TOBE_2 GGPLMPOG_00243 547043.BIFPSEUDO_03196 4.03e-168 470.0 COG3279@1|root,COG3279@2|Bacteria,2GKK5@201174|Actinobacteria,4CZAU@85004|Bifidobacteriales 201174|Actinobacteria K LytTr DNA-binding domain - - - - - - - - - - - - LytTR,Response_reg GGPLMPOG_00244 547043.BIFPSEUDO_03197 5.05e-314 858.0 COG3290@1|root,COG3290@2|Bacteria,2IAW1@201174|Actinobacteria,4CZ3D@85004|Bifidobacteriales 201174|Actinobacteria T GHKL domain - - - - - - - - - - - - HATPase_c_5 GGPLMPOG_00245 547043.BIFPSEUDO_03198 1.87e-140 410.0 2DDMI@1|root,2ZIJN@2|Bacteria,2ICIR@201174|Actinobacteria,4D00F@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - FIVAR GGPLMPOG_00246 547043.BIFPSEUDO_03199 2.4e-275 758.0 COG0038@1|root,COG0038@2|Bacteria,2GPPN@201174|Actinobacteria,4CZPX@85004|Bifidobacteriales 201174|Actinobacteria P Voltage gated chloride channel - - - ko:K03281 - - - - ko00000 2.A.49 - - Voltage_CLC GGPLMPOG_00247 78346.BRUM_1679 3.4e-255 700.0 COG2421@1|root,COG2421@2|Bacteria,2HQSF@201174|Actinobacteria,4D0CG@85004|Bifidobacteriales 201174|Actinobacteria C Acetamidase/Formamidase family - - - - - - - - - - - - FmdA_AmdA GGPLMPOG_00248 77635.BISU_0684 4.62e-108 318.0 COG2186@1|root,COG2186@2|Bacteria,2HWNC@201174|Actinobacteria,4D0ZE@85004|Bifidobacteriales 201174|Actinobacteria K FCD - - - ko:K05799 - - - - ko00000,ko03000 - - - FCD,GntR GGPLMPOG_00249 78346.BRUM_1680 8.63e-181 504.0 COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria,4D0D9@85004|Bifidobacteriales 201174|Actinobacteria E ATPases associated with a variety of cellular activities - - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran GGPLMPOG_00250 78346.BRUM_1681 7.85e-152 430.0 COG0765@1|root,COG0765@2|Bacteria,2HF3Q@201174|Actinobacteria,4D0M0@85004|Bifidobacteriales 201174|Actinobacteria U Binding-protein-dependent transport system inner membrane component - - - ko:K02029 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 GGPLMPOG_00251 78346.BRUM_1682 6.08e-194 539.0 COG0834@1|root,COG0834@2|Bacteria,2IAIW@201174|Actinobacteria,4D20X@85004|Bifidobacteriales 201174|Actinobacteria ET Bacterial periplasmic substrate-binding proteins - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 GGPLMPOG_00252 78346.BRUM_1683 8.62e-274 751.0 COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,4CYVP@85004|Bifidobacteriales 201174|Actinobacteria E Aminotransferase class I and II - - 2.6.1.1 ko:K00812,ko:K10907 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 GGPLMPOG_00253 566552.BIFCAT_01419 1.61e-126 360.0 2A9VD@1|root,30Z38@2|Bacteria,2I88K@201174|Actinobacteria,4D0A0@85004|Bifidobacteriales 201174|Actinobacteria S GtrA-like protein - - - - - - - - - - - - GtrA GGPLMPOG_00254 566552.BIFCAT_01418 0.0 1569.0 COG1472@1|root,COG1472@2|Bacteria,2GJ5H@201174|Actinobacteria,4CZ2P@85004|Bifidobacteriales 201174|Actinobacteria G Glycosyl hydrolase family 3 N-terminal domain protein - - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C GGPLMPOG_00255 566552.BIFCAT_01416 3.38e-146 413.0 COG0671@1|root,COG0671@2|Bacteria,2GNTK@201174|Actinobacteria,4D0FE@85004|Bifidobacteriales 201174|Actinobacteria I Psort location CytoplasmicMembrane, score - - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2 GGPLMPOG_00256 566552.BIFCAT_01415 1.9e-104 301.0 COG0454@1|root,COG0456@2|Bacteria,2IHRD@201174|Actinobacteria,4D10V@85004|Bifidobacteriales 201174|Actinobacteria K Psort location Cytoplasmic, score 8.87 ypeA - 2.3.1.1 ko:K22477 ko00220,ko01210,ko01230,map00220,map01210,map01230 M00028 R00259 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - Acetyltransf_1 GGPLMPOG_00257 566552.BIFCAT_01414 6.15e-146 411.0 COG1136@1|root,COG1136@2|Bacteria,2I7UV@201174|Actinobacteria,4CZ1C@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter, ATP-binding protein vex - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran GGPLMPOG_00258 566552.BIFCAT_01413 4.77e-271 744.0 COG0577@1|root,COG0577@2|Bacteria,2IA7B@201174|Actinobacteria,4CZJM@85004|Bifidobacteriales 201174|Actinobacteria V Efflux ABC transporter, permease protein - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX GGPLMPOG_00259 547043.BIFPSEUDO_03215 2.2e-304 833.0 COG0577@1|root,COG0577@2|Bacteria,2I99G@201174|Actinobacteria,4D0H6@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter permease - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD GGPLMPOG_00260 566552.BIFCAT_01411 0.0 926.0 COG2211@1|root,COG2211@2|Bacteria,2HD4Y@201174|Actinobacteria,4CZRA@85004|Bifidobacteriales 201174|Actinobacteria G Psort location CytoplasmicMembrane, score 10.00 gph - - ko:K16209 - - - - ko00000,ko02000 2.A.2.2 - - MFS_2 GGPLMPOG_00261 566552.BIFCAT_01410 0.0 2090.0 COG3250@1|root,COG3250@2|Bacteria,2GMAT@201174|Actinobacteria,4CYYS@85004|Bifidobacteriales 201174|Actinobacteria G Psort location Cytoplasmic, score 8.87 - - 3.2.1.23 ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 - R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 - - - Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Laminin_G_3 GGPLMPOG_00262 547043.BIFPSEUDO_03218 4.67e-19 85.5 COG1609@1|root,COG1609@2|Bacteria,2H5ZG@201174|Actinobacteria,4CZ8A@85004|Bifidobacteriales 201174|Actinobacteria K Transcriptional regulator, LacI family - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 GGPLMPOG_00263 566552.BIFCAT_01408 1.41e-17 73.9 2B4NV@1|root,325VP@2|Bacteria,2HB5J@201174|Actinobacteria,4D2KK@85004|Bifidobacteriales 201174|Actinobacteria S Psort location Extracellular, score 8.82 - - - - - - - - - - - - - GGPLMPOG_00264 547043.BIFPSEUDO_04261 0.0 1116.0 COG0492@1|root,COG3634@1|root,COG0492@2|Bacteria,COG3634@2|Bacteria,2GKD2@201174|Actinobacteria,4CZ6G@85004|Bifidobacteriales 201174|Actinobacteria C Thioredoxin domain - - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Thioredoxin_3 GGPLMPOG_00265 547043.BIFPSEUDO_04262 1.22e-138 391.0 COG0450@1|root,COG0450@2|Bacteria,2GM74@201174|Actinobacteria,4CZXS@85004|Bifidobacteriales 201174|Actinobacteria O C-terminal domain of 1-Cys peroxiredoxin ahpC - 1.11.1.15 ko:K03386 ko04214,map04214 - - - ko00000,ko00001,ko01000,ko04147 - - - 1-cysPrx_C,AhpC-TSA GGPLMPOG_00267 566552.BIFCAT_01765 0.0 1352.0 COG0480@1|root,COG0480@2|Bacteria,2GJ64@201174|Actinobacteria,4CZM5@85004|Bifidobacteriales 201174|Actinobacteria J Elongation factor G, domain IV tetM - - ko:K18220 - - - - br01600,ko00000,ko01504 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU GGPLMPOG_00269 566552.BIFCAT_01763 6.35e-276 756.0 COG1055@1|root,COG1055@2|Bacteria,2GP6U@201174|Actinobacteria,4CZ37@85004|Bifidobacteriales 201174|Actinobacteria P Citrate transporter - - - - - - - - - - - - CitMHS GGPLMPOG_00270 566552.BIFCAT_01761 0.0 1351.0 COG0358@1|root,COG0358@2|Bacteria,2GJFX@201174|Actinobacteria,4CYZG@85004|Bifidobacteriales 201174|Actinobacteria L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,DnaG_DnaB_bind,Toprim_4,Toprim_N,zf-CHC2 GGPLMPOG_00271 547043.BIFPSEUDO_02397 0.0 1054.0 COG0787@1|root,COG0787@2|Bacteria,2GM2Y@201174|Actinobacteria,4CZ2Q@85004|Bifidobacteriales 201174|Actinobacteria M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N GGPLMPOG_00272 547043.BIFPSEUDO_02398 0.0 936.0 COG0531@1|root,COG0531@2|Bacteria,2GJ75@201174|Actinobacteria,4CYZA@85004|Bifidobacteriales 201174|Actinobacteria E aromatic amino acid transport protein AroP K03293 aap1 - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 GGPLMPOG_00273 566552.BIFCAT_01758 6.51e-131 371.0 COG1670@1|root,COG1670@2|Bacteria,2HBE2@201174|Actinobacteria,4CZTR@85004|Bifidobacteriales 201174|Actinobacteria J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins cysE - - - - - - - - - - - - GGPLMPOG_00274 547043.BIFPSEUDO_02401 1.29e-117 337.0 COG1854@1|root,COG1854@2|Bacteria,2GJVF@201174|Actinobacteria,4CYZ4@85004|Bifidobacteriales 201174|Actinobacteria H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) luxS - 4.4.1.21 ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 M00609 R01291 RC00069,RC01929 ko00000,ko00001,ko00002,ko01000 - - - LuxS GGPLMPOG_00275 547043.BIFPSEUDO_02402 0.0 1263.0 COG0514@1|root,COG0514@2|Bacteria,2GJSS@201174|Actinobacteria,4CZ0I@85004|Bifidobacteriales 201174|Actinobacteria L ATP-dependent DNA helicase RecQ recQ - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind GGPLMPOG_00276 547043.BIFPSEUDO_02403 0.0 1752.0 COG0577@1|root,COG1136@1|root,COG0577@2|Bacteria,COG1136@2|Bacteria,2GK3I@201174|Actinobacteria,4D0AY@85004|Bifidobacteriales 201174|Actinobacteria V ATPases associated with a variety of cellular activities - - - ko:K02003,ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,FtsX GGPLMPOG_00277 547043.BIFPSEUDO_02405 1.1e-278 762.0 COG0626@1|root,COG0626@2|Bacteria,2GJ5S@201174|Actinobacteria,4CYY2@85004|Bifidobacteriales 201174|Actinobacteria E Cys/Met metabolism PLP-dependent enzyme metB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48 ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00420,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv1079 Cys_Met_Meta_PP GGPLMPOG_00278 547043.BIFPSEUDO_02406 2.85e-243 668.0 COG0031@1|root,COG0031@2|Bacteria,2GIXE@201174|Actinobacteria,4CYQ4@85004|Bifidobacteriales 201174|Actinobacteria E Pyridoxal-phosphate dependent enzyme cbs GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0016020,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363 2.5.1.47,4.2.1.22 ko:K01697,ko:K01738 ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021,M00035,M00338 R00891,R00897,R01290,R03601,R04859,R04942 RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - CBS,PALP GGPLMPOG_00279 547043.BIFPSEUDO_02407 1.03e-177 495.0 COG4608@1|root,COG4608@2|Bacteria,2GP46@201174|Actinobacteria,4CYXD@85004|Bifidobacteriales 201174|Actinobacteria E ATPases associated with a variety of cellular activities - - - ko:K02032 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran GGPLMPOG_00280 547043.BIFPSEUDO_02408 4.79e-177 494.0 COG0444@1|root,COG0444@2|Bacteria,2GIXV@201174|Actinobacteria,4CZ3U@85004|Bifidobacteriales 201174|Actinobacteria EP oligopeptide transport protein of the ABC superfamily, ATP-binding component - - - ko:K02031 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran GGPLMPOG_00281 547043.BIFPSEUDO_02409 4.44e-200 556.0 COG1173@1|root,COG1173@2|Bacteria,2GNQ5@201174|Actinobacteria,4CZ84@85004|Bifidobacteriales 201174|Actinobacteria EP Binding-protein-dependent transport system inner membrane component - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 GGPLMPOG_00282 547043.BIFPSEUDO_02410 8.06e-213 590.0 COG0601@1|root,COG0601@2|Bacteria,2GK0Z@201174|Actinobacteria,4CYST@85004|Bifidobacteriales 201174|Actinobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 GGPLMPOG_00283 547043.BIFPSEUDO_02411 0.0 1065.0 COG0747@1|root,COG0747@2|Bacteria,2GJ4B@201174|Actinobacteria,4CYWF@85004|Bifidobacteriales 201174|Actinobacteria E ABC transporter, substrate-binding protein, family 5 - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 GGPLMPOG_00284 547043.BIFPSEUDO_02412 5.89e-309 843.0 COG0452@1|root,COG0452@2|Bacteria,2GJGJ@201174|Actinobacteria,4D0GJ@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine coaBC GO:0003674,GO:0003824,GO:0004633,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.36,6.3.2.5 ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - - DFP,Flavoprotein GGPLMPOG_00285 547043.BIFPSEUDO_02413 1.1e-182 508.0 COG1521@1|root,COG1521@2|Bacteria,2GMRQ@201174|Actinobacteria,4CZQS@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis coaX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.1.33 ko:K03525 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Pan_kinase GGPLMPOG_00286 547043.BIFPSEUDO_02417 0.0 949.0 COG1653@1|root,COG1653@2|Bacteria,2GJIP@201174|Actinobacteria,4CYRE@85004|Bifidobacteriales 201174|Actinobacteria G Bacterial extracellular solute-binding protein - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_1,SBP_bac_8 GGPLMPOG_00287 547043.BIFPSEUDO_02418 5.82e-281 770.0 COG1653@1|root,COG1653@2|Bacteria,2GJIP@201174|Actinobacteria,4CYRE@85004|Bifidobacteriales 201174|Actinobacteria G Bacterial extracellular solute-binding protein - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_1,SBP_bac_8 GGPLMPOG_00288 547043.BIFPSEUDO_02418 9.09e-15 73.9 COG1653@1|root,COG1653@2|Bacteria,2GJIP@201174|Actinobacteria,4CYRE@85004|Bifidobacteriales 201174|Actinobacteria G Bacterial extracellular solute-binding protein - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_1,SBP_bac_8 GGPLMPOG_00289 547043.BIFPSEUDO_02419 0.0 1068.0 COG3534@1|root,COG3534@2|Bacteria,2GMAK@201174|Actinobacteria,4CYXS@85004|Bifidobacteriales 201174|Actinobacteria G arabinose metabolic process abfA1 - 3.2.1.55 ko:K01209 ko00520,map00520 - R01762 - ko00000,ko00001,ko01000 - GH51 - Alpha-L-AF_C GGPLMPOG_00290 547043.BIFPSEUDO_02420 0.0 1425.0 COG1874@1|root,COG1874@2|Bacteria,2GMDT@201174|Actinobacteria,4CZ38@85004|Bifidobacteriales 201174|Actinobacteria G Psort location Cytoplasmic, score 8.87 bga1 - 3.2.1.23 ko:K12308 ko00052,map00052 - R01105 RC00452 ko00000,ko00001,ko01000 - - - Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M GGPLMPOG_00291 547043.BIFPSEUDO_03919 2.5e-94 276.0 COG2963@1|root,COG2963@2|Bacteria,2IF4K@201174|Actinobacteria,4D0JP@85004|Bifidobacteriales 201174|Actinobacteria L Helix-turn-helix domain - - - - - - - - - - - - HTH_23,HTH_28 GGPLMPOG_00293 566552.BIFCAT_00560 0.0 1669.0 28KWM@1|root,2ZACS@2|Bacteria,2I981@201174|Actinobacteria,4D04V@85004|Bifidobacteriales 201174|Actinobacteria S LPXTG-motif cell wall anchor domain protein - - - - - - - - - - - - CBM_X2 GGPLMPOG_00294 547043.BIFPSEUDO_03922 3.4e-215 601.0 COG0534@1|root,COG0534@2|Bacteria,2GJE3@201174|Actinobacteria,4CZ75@85004|Bifidobacteriales 201174|Actinobacteria V MatE dinF - - - - - - - - - - - MatE GGPLMPOG_00295 547043.BIFPSEUDO_03922 2.26e-75 238.0 COG0534@1|root,COG0534@2|Bacteria,2GJE3@201174|Actinobacteria,4CZ75@85004|Bifidobacteriales 201174|Actinobacteria V MatE dinF - - - - - - - - - - - MatE GGPLMPOG_00296 547043.BIFPSEUDO_02914 7.75e-130 375.0 COG0652@1|root,COG0652@2|Bacteria,2IFUE@201174|Actinobacteria,4CZSU@85004|Bifidobacteriales 201174|Actinobacteria G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ppiA GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030312,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0071944,GO:0140096,GO:1901564 5.2.1.8 ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 - - - ko00000,ko00001,ko01000,ko03110,ko04147 - - - Pro_isomerase GGPLMPOG_00297 547043.BIFPSEUDO_02916 0.0 1523.0 COG0317@1|root,COG0317@2|Bacteria,2GJYQ@201174|Actinobacteria,4CZCW@85004|Bifidobacteriales 201174|Actinobacteria KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009259,GO:0009260,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0015969,GO:0015970,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034035,GO:0034036,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042578,GO:0042594,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044419,GO:0044464,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051704,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.6.5,3.1.7.2 ko:K00951,ko:K01139 ko00230,map00230 - R00336,R00429 RC00002,RC00078 ko00000,ko00001,ko01000,ko03009 - - - ACT_4,HD_4,RelA_SpoT,TGS GGPLMPOG_00298 547043.BIFPSEUDO_02917 5.02e-110 316.0 COG0756@1|root,COG0756@2|Bacteria,2IHYY@201174|Actinobacteria,4CZUJ@85004|Bifidobacteriales 201174|Actinobacteria F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA dut - 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase GGPLMPOG_00299 547043.BIFPSEUDO_02918 8.5e-63 192.0 2ATJW@1|root,3361K@2|Bacteria,2I80Y@201174|Actinobacteria,4D10Y@85004|Bifidobacteriales 201174|Actinobacteria S Domain of unknown function (DUF4193) - - - - - - - - - - - - DUF4193 GGPLMPOG_00300 547043.BIFPSEUDO_02919 1.37e-228 632.0 29W72@1|root,30HS9@2|Bacteria,2HZB4@201174|Actinobacteria,4CZFJ@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF3071) - - - - - - - - - - - - DUF3071 GGPLMPOG_00301 547043.BIFPSEUDO_02920 2.06e-299 816.0 COG1524@1|root,COG1524@2|Bacteria,2GISU@201174|Actinobacteria,4CZCK@85004|Bifidobacteriales 201174|Actinobacteria S Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - Phosphodiest GGPLMPOG_00302 547043.BIFPSEUDO_02921 0.0 1686.0 COG0188@1|root,COG0188@2|Bacteria,2GJ2Q@201174|Actinobacteria,4CYVH@85004|Bifidobacteriales 201174|Actinobacteria L DNA topoisomerase (ATP-hydrolyzing) gyrA2 - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV GGPLMPOG_00303 547043.BIFPSEUDO_02922 0.0 3018.0 COG1201@1|root,COG1201@2|Bacteria,2GJG3@201174|Actinobacteria,4D01F@85004|Bifidobacteriales 201174|Actinobacteria L DEAD DEAH box helicase lhr - - ko:K03724 - - - - ko00000,ko01000,ko03400 - - - DEAD,DEAD_assoc,HTH_42,Helicase_C GGPLMPOG_00304 547043.BIFPSEUDO_02923 6.21e-43 140.0 COG3655@1|root,COG3655@2|Bacteria,2GQZM@201174|Actinobacteria,4D1EQ@85004|Bifidobacteriales 201174|Actinobacteria K Cro/C1-type HTH DNA-binding domain - - - ko:K07727 - - - - ko00000,ko03000 - - - HTH_26 GGPLMPOG_00305 547043.BIFPSEUDO_02924 7.86e-103 299.0 2DU83@1|root,33PAY@2|Bacteria,2IMPR@201174|Actinobacteria,4D19W@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF2975) - - - - - - - - - - - - DUF2975 GGPLMPOG_00306 547043.BIFPSEUDO_02926 1.05e-307 840.0 COG0642@1|root,COG2205@2|Bacteria,2I4ZW@201174|Actinobacteria,4CZGX@85004|Bifidobacteriales 201174|Actinobacteria T Domain of unknown function (DUF4173) - - - - - - - - - - - - DUF4173 GGPLMPOG_00307 547043.BIFPSEUDO_02927 1.72e-286 783.0 COG0738@1|root,COG0738@2|Bacteria,2HWKN@201174|Actinobacteria,4CYRZ@85004|Bifidobacteriales 201174|Actinobacteria G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 GGPLMPOG_00308 547043.BIFPSEUDO_02928 0.0 1512.0 COG0187@1|root,COG0187@2|Bacteria,2GM1E@201174|Actinobacteria,4CYXR@85004|Bifidobacteriales 201174|Actinobacteria L DNA topoisomerase (ATP-hydrolyzing) gyrB2 - 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim GGPLMPOG_00309 547043.BIFPSEUDO_02929 3.32e-226 635.0 COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4CZQC@85004|Bifidobacteriales 201174|Actinobacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth sigA - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 GGPLMPOG_00310 547043.BIFPSEUDO_02930 2.58e-152 430.0 2B5AP@1|root,31Y4U@2|Bacteria,2IF9M@201174|Actinobacteria,4D15J@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - DUF4192 GGPLMPOG_00311 547043.BIFPSEUDO_02931 3.13e-252 693.0 COG0142@1|root,COG0142@2|Bacteria,2GJEK@201174|Actinobacteria,4CZQV@85004|Bifidobacteriales 201174|Actinobacteria H Belongs to the FPP GGPP synthase family idsA - 2.5.1.1,2.5.1.10,2.5.1.29 ko:K13787 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00365 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt GGPLMPOG_00312 547043.BIFPSEUDO_02932 0.0 1418.0 COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4CYTR@85004|Bifidobacteriales 201174|Actinobacteria KLT PASTA pknL GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase GGPLMPOG_00313 547043.BIFPSEUDO_04468 6.14e-180 502.0 COG0657@1|root,COG0657@2|Bacteria,2GNKU@201174|Actinobacteria,4CZVA@85004|Bifidobacteriales 201174|Actinobacteria I alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_3,Peptidase_S9 GGPLMPOG_00314 1437610.BREU_0546 6.71e-39 140.0 COG0657@1|root,COG0657@2|Bacteria,2GNKU@201174|Actinobacteria,4CZVA@85004|Bifidobacteriales 201174|Actinobacteria I alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_3,Peptidase_S9 GGPLMPOG_00315 547043.BIFPSEUDO_04466 1.76e-183 509.0 COG0846@1|root,COG0846@2|Bacteria,2GJI3@201174|Actinobacteria,4CYUW@85004|Bifidobacteriales 201174|Actinobacteria K Sir2 family cobB2 - - ko:K12410 - - - - ko00000,ko01000 - - - SIR2 GGPLMPOG_00316 547043.BIFPSEUDO_04465 1.76e-296 810.0 COG1171@1|root,COG1171@2|Bacteria,2GJAG@201174|Actinobacteria,4CYW0@85004|Bifidobacteriales 201174|Actinobacteria E Pyridoxal-phosphate dependent enzyme ilvA GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0016020,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901605 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv1559 PALP,Thr_dehydrat_C GGPLMPOG_00317 547043.BIFPSEUDO_04464 0.0 1264.0 COG0366@1|root,COG0366@2|Bacteria,2GKS4@201174|Actinobacteria,4CZT7@85004|Bifidobacteriales 201174|Actinobacteria G Alpha amylase, catalytic domain protein - - 3.2.1.10 ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00801,R01718,R01791,R06199 RC00028,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,DUF3459,Malt_amylase_C GGPLMPOG_00318 566552.BIFCAT_01128 1.06e-198 551.0 COG0395@1|root,COG0395@2|Bacteria,2GNQW@201174|Actinobacteria,4D02Q@85004|Bifidobacteriales 201174|Actinobacteria G Binding-protein-dependent transport system inner membrane component - - - ko:K10119 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - BPD_transp_1 GGPLMPOG_00319 547043.BIFPSEUDO_04462 3.02e-205 570.0 COG1175@1|root,COG1175@2|Bacteria,2GKJI@201174|Actinobacteria,4CZPG@85004|Bifidobacteriales 201174|Actinobacteria G Binding-protein-dependent transport system inner membrane component - - - ko:K10118 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - BPD_transp_1 GGPLMPOG_00320 547043.BIFPSEUDO_04461 6.1e-313 852.0 COG1653@1|root,COG1653@2|Bacteria,2GN9T@201174|Actinobacteria,4CZ4V@85004|Bifidobacteriales 201174|Actinobacteria G Bacterial extracellular solute-binding protein - - - ko:K10117 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - SBP_bac_1,SBP_bac_8 GGPLMPOG_00321 547043.BIFPSEUDO_04460 7.06e-293 799.0 COG1846@1|root,COG1940@1|root,COG1846@2|Bacteria,COG1940@2|Bacteria,2GMBH@201174|Actinobacteria,4CZK4@85004|Bifidobacteriales 201174|Actinobacteria GK ROK family - - - - - - - - - - - - ROK GGPLMPOG_00322 547043.BIFPSEUDO_04459 0.0 1565.0 COG3345@1|root,COG3345@2|Bacteria,2GJJ1@201174|Actinobacteria,4CZJB@85004|Bifidobacteriales 201174|Actinobacteria G Glycosyl hydrolase family 36 N-terminal domain - - 3.2.1.22 ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 - R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 - - - Glyco_hydro_36C,Glyco_hydro_36N,Melibiase GGPLMPOG_00323 547043.BIFPSEUDO_04457 1.35e-105 305.0 COG0590@1|root,COG0590@2|Bacteria,2IM3Z@201174|Actinobacteria,4D0V0@85004|Bifidobacteriales 201174|Actinobacteria FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) tadA - 3.5.4.1,3.5.4.33 ko:K01485,ko:K11991 ko00240,ko00330,ko01100,map00240,map00330,map01100 - R00974,R01411,R02922,R10223 RC00074,RC00477,RC00514,RC00809 ko00000,ko00001,ko01000,ko03016 - - - MafB19-deam,dCMP_cyt_deam_1 GGPLMPOG_00324 566552.BIFCAT_01121 0.0 1258.0 COG0025@1|root,COG0025@2|Bacteria,2GIUT@201174|Actinobacteria,4CZC4@85004|Bifidobacteriales 201174|Actinobacteria P Sodium/hydrogen exchanger family nhaP - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger GGPLMPOG_00325 566552.BIFCAT_01120 3.86e-195 540.0 COG0400@1|root,COG0400@2|Bacteria,2I5NR@201174|Actinobacteria,4CZJQ@85004|Bifidobacteriales 201174|Actinobacteria S Phospholipase/Carboxylesterase - - - ko:K06999 - - - - ko00000 - - - Abhydrolase_2 GGPLMPOG_00326 547043.BIFPSEUDO_04453 1.73e-143 404.0 COG0717@1|root,COG0717@2|Bacteria,2GKQQ@201174|Actinobacteria,4CZEB@85004|Bifidobacteriales 201174|Actinobacteria F Belongs to the dCTP deaminase family dcd GO:0003674,GO:0003824,GO:0004170,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0019239,GO:0033973,GO:0047429 3.5.4.13 ko:K01494 ko00240,ko01100,map00240,map01100 M00053 R00568,R02325 RC00074 ko00000,ko00001,ko00002,ko01000 - - - DCD GGPLMPOG_00327 78344.BIGA_1751 7.8e-58 189.0 COG2801@1|root,COG2801@2|Bacteria,2GKW1@201174|Actinobacteria,4D05P@85004|Bifidobacteriales 201174|Actinobacteria L PFAM Integrase catalytic - - - - - - - - - - - - HTH_21,rve,rve_2 GGPLMPOG_00328 342451.SSP0618 4.86e-36 134.0 COG0765@1|root,COG0765@2|Bacteria,1UZ2C@1239|Firmicutes,4IQKI@91061|Bacilli,4GYMF@90964|Staphylococcaceae 91061|Bacilli P Binding-protein-dependent transport system inner membrane component - - - ko:K16959 ko02010,map02010 M00585 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.13 - - BPD_transp_1 GGPLMPOG_00329 536227.CcarbDRAFT_4311 1.23e-51 174.0 COG0765@1|root,COG0765@2|Bacteria,1V4MI@1239|Firmicutes,25C2X@186801|Clostridia,36JPG@31979|Clostridiaceae 186801|Clostridia E Binding-protein-dependent transport system inner membrane component - - - ko:K16958 ko02010,map02010 M00585 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.13 - - BPD_transp_1 GGPLMPOG_00330 573.JG24_17575 3.5e-93 281.0 COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,1RMX1@1236|Gammaproteobacteria 1236|Gammaproteobacteria E (ABC) transporter tcyC - 3.6.3.21 ko:K02028,ko:K02029,ko:K10004,ko:K10010,ko:K10038,ko:K16960,ko:K16963 ko02010,ko02020,map02010,map02020 M00227,M00230,M00234,M00236,M00585,M00586 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3,3.A.1.3.10,3.A.1.3.13,3.A.1.3.14,3.A.1.3.19,3.A.1.3.2,3.A.1.3.4 - - ABC_tran GGPLMPOG_00331 78346.BRUM_1711 7.47e-134 392.0 COG0240@1|root,COG0240@2|Bacteria 2|Bacteria I glycerol-3-phosphate dehydrogenase [NAD(P)+] activity odh - 1.5.1.28 ko:K04940 - - - - ko00000,ko01000 - - - ApbA,F420_oxidored,NAD_Gly3P_dh_N,NAD_binding_2,Octopine_DH GGPLMPOG_00332 642227.HA49_20500 2.65e-23 97.4 COG0834@1|root,COG0834@2|Bacteria,1R92C@1224|Proteobacteria,1S1CF@1236|Gammaproteobacteria,4BVHU@82986|Tatumella 1236|Gammaproteobacteria ET Bacterial periplasmic substrate-binding proteins - - - ko:K16957 ko02010,map02010 M00585 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.13 - - SBP_bac_3 GGPLMPOG_00333 518635.BIFANG_03565 4.65e-304 826.0 COG2723@1|root,COG2723@2|Bacteria,2GJAF@201174|Actinobacteria,4CYPX@85004|Bifidobacteriales 201174|Actinobacteria G Glycosyl hydrolase family 1 - - 3.2.1.21 ko:K05350 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - - - Glyco_hydro_1 GGPLMPOG_00334 518635.BIFANG_03564 7.79e-203 562.0 COG0395@1|root,COG0395@2|Bacteria,2GMTH@201174|Actinobacteria,4CZQ9@85004|Bifidobacteriales 201174|Actinobacteria U Binding-protein-dependent transport system inner membrane component - - - ko:K02026,ko:K10190 ko02010,map02010 M00199,M00207 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.4 - - BPD_transp_1 GGPLMPOG_00335 518635.BIFANG_03563 1.63e-206 572.0 COG1175@1|root,COG1175@2|Bacteria,2GKBJ@201174|Actinobacteria,4CZDV@85004|Bifidobacteriales 201174|Actinobacteria U Binding-protein-dependent transport system inner membrane component - - - ko:K02025 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 GGPLMPOG_00336 518635.BIFANG_03562 7.01e-304 829.0 COG1653@1|root,COG1653@2|Bacteria,2GM4E@201174|Actinobacteria,4CZ8S@85004|Bifidobacteriales 201174|Actinobacteria G Bacterial extracellular solute-binding protein - - - ko:K02027,ko:K10227 ko02010,map02010 M00200,M00207 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.5 - - SBP_bac_1,SBP_bac_8 GGPLMPOG_00337 518635.BIFANG_03561 1.06e-258 710.0 COG1609@1|root,COG1609@2|Bacteria,2GJV7@201174|Actinobacteria,4D04H@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn _helix lactose operon repressor - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 GGPLMPOG_00338 547043.BIFPSEUDO_02434 8.3e-105 303.0 COG0691@1|root,COG0691@2|Bacteria,2GJX1@201174|Actinobacteria,4CZG4@85004|Bifidobacteriales 201174|Actinobacteria J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA smpB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K03664 - - - - ko00000 - - - SmpB GGPLMPOG_00339 547043.BIFPSEUDO_02432 2.04e-205 570.0 COG0834@1|root,COG0834@2|Bacteria,2GJQW@201174|Actinobacteria,4CZ6H@85004|Bifidobacteriales 201174|Actinobacteria ET ABC transporter, substrate-binding protein, family 3 glnH - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 GGPLMPOG_00340 547043.BIFPSEUDO_02431 7.62e-206 572.0 COG0834@1|root,COG0834@2|Bacteria,2GJQW@201174|Actinobacteria,4CZ6H@85004|Bifidobacteriales 201174|Actinobacteria ET ABC transporter, substrate-binding protein, family 3 glnH - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 GGPLMPOG_00341 547043.BIFPSEUDO_02430 7.61e-201 558.0 COG0834@1|root,COG0834@2|Bacteria,2GJQW@201174|Actinobacteria,4CZ6H@85004|Bifidobacteriales 201174|Actinobacteria ET ABC transporter, substrate-binding protein, family 3 glnH - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 GGPLMPOG_00342 547043.BIFPSEUDO_02428 6.26e-222 613.0 COG0765@1|root,COG0765@2|Bacteria,2GJJ9@201174|Actinobacteria,4CYSN@85004|Bifidobacteriales 201174|Actinobacteria E Binding-protein-dependent transport system inner membrane component yecS - - ko:K02029 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 GGPLMPOG_00343 547043.BIFPSEUDO_02427 5.24e-187 520.0 COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria,4CZSB@85004|Bifidobacteriales 201174|Actinobacteria E ATPases associated with a variety of cellular activities tcyC - 3.6.3.21 ko:K02028,ko:K02029 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran GGPLMPOG_00344 547043.BIFPSEUDO_02426 0.0 1245.0 COG0449@1|root,COG0449@2|Bacteria,2GKH0@201174|Actinobacteria,4CZ1G@85004|Bifidobacteriales 201174|Actinobacteria M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - iNJ661.Rv3436c GATase_6,SIS GGPLMPOG_00345 547043.BIFPSEUDO_02425 2.07e-186 517.0 COG0564@1|root,COG0564@2|Bacteria,2GJ2Z@201174|Actinobacteria,4CZB2@85004|Bifidobacteriales 201174|Actinobacteria J RNA pseudouridylate synthase - - 5.4.99.28,5.4.99.29 ko:K06177 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2 GGPLMPOG_00346 547043.BIFPSEUDO_02424 3.12e-290 795.0 COG3633@1|root,COG3633@2|Bacteria,2I861@201174|Actinobacteria,4D300@85004|Bifidobacteriales 201174|Actinobacteria E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) sstT - - ko:K07862 - - - - ko00000,ko02000 2.A.23.4 - - SDF GGPLMPOG_00347 547043.BIFPSEUDO_02423 5.33e-243 667.0 COG1609@1|root,COG1609@2|Bacteria,2GK1X@201174|Actinobacteria,4CZWK@85004|Bifidobacteriales 201174|Actinobacteria K Periplasmic binding protein domain - - - - - - - - - - - - LacI,Peripla_BP_3 GGPLMPOG_00348 326426.Bbr_0318 2.85e-25 96.7 2EK5K@1|root,33DW0@2|Bacteria,2GSM4@201174|Actinobacteria,4D1J2@85004|Bifidobacteriales 201174|Actinobacteria S Putative phage holin Dp-1 - - - - - - - - - - - - Phage_holin_Dp1 GGPLMPOG_00349 401473.BDP_1477 8.28e-109 333.0 COG1388@1|root,COG3757@1|root,COG1388@2|Bacteria,COG3757@2|Bacteria,2I2GA@201174|Actinobacteria,4D07F@85004|Bifidobacteriales 201174|Actinobacteria M Glycosyl hydrolases family 25 - - - - - - - - - - - - CW_7,Glyco_hydro_25,LysM GGPLMPOG_00350 566552.BIFCAT_00300 2.9e-28 105.0 2BJPU@1|root,32E1F@2|Bacteria,2GZ2E@201174|Actinobacteria,4D1PK@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_00353 1680.BADO_1221 5.13e-123 362.0 COG3344@1|root,COG3344@2|Bacteria 2|Bacteria L reverse transcriptase - - - ko:K15342 - - - - ko00000,ko02048,ko03400 - - - RVT_1 GGPLMPOG_00354 1680.BADO_1222 1.43e-229 649.0 2DKX6@1|root,30QMZ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - GGPLMPOG_00356 1680.BADO_1224 2.15e-183 513.0 COG0582@1|root,COG0582@2|Bacteria 2|Bacteria L DNA integration - - - - - - - - - - - - Phage_int_SAM_3,Phage_integrase GGPLMPOG_00357 547043.BIFPSEUDO_03966 0.0 1900.0 COG1472@1|root,COG1472@2|Bacteria,2GQQR@201174|Actinobacteria,4CZ02@85004|Bifidobacteriales 201174|Actinobacteria G Fibronectin type III-like domain - - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C GGPLMPOG_00358 547043.BIFPSEUDO_03968 0.0 1244.0 COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria,4CYQG@85004|Bifidobacteriales 201174|Actinobacteria KLT Protein tyrosine kinase - - - - - - - - - - - - Pkinase GGPLMPOG_00359 547043.BIFPSEUDO_03969 1.62e-213 592.0 COG1651@1|root,COG1651@2|Bacteria,2GN3N@201174|Actinobacteria,4CZBD@85004|Bifidobacteriales 201174|Actinobacteria O Thioredoxin - - - - - - - - - - - - Thioredoxin_4 GGPLMPOG_00361 547043.BIFPSEUDO_03971 2.48e-255 711.0 COG3583@1|root,COG3583@2|Bacteria,2H4RU@201174|Actinobacteria,4CYY0@85004|Bifidobacteriales 201174|Actinobacteria S G5 rpfB GO:0005575,GO:0005576,GO:0008150,GO:0009892,GO:0009893,GO:0010468,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019222,GO:0022611,GO:0032502,GO:0040008,GO:0040009,GO:0040010,GO:0044111,GO:0044114,GO:0044115,GO:0044403,GO:0044419,GO:0045927,GO:0048518,GO:0048519,GO:0050789,GO:0051704,GO:0060255,GO:0065007,GO:0085016 - ko:K21688 - - - - ko00000 - - - DUF348,G5,Transglycosylas GGPLMPOG_00362 547043.BIFPSEUDO_03972 4.25e-220 607.0 COG0030@1|root,COG0030@2|Bacteria,2GKBT@201174|Actinobacteria,4CYS9@85004|Bifidobacteriales 201174|Actinobacteria J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits ksgA GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 ko:K02528 - - R10716 RC00003,RC03257 ko00000,ko01000,ko03009 - - - RrnaAD GGPLMPOG_00363 547043.BIFPSEUDO_03973 1.47e-212 587.0 COG1947@1|root,COG1947@2|Bacteria,2GKXD@201174|Actinobacteria,4CZMW@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol ispE GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0040007,GO:0044237,GO:0050515 2.7.1.148 ko:K00919 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05634 RC00002,RC01439 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N GGPLMPOG_00364 547043.BIFPSEUDO_03974 8.42e-142 400.0 2E1BJ@1|root,32WRF@2|Bacteria,2IKG0@201174|Actinobacteria,4D0S1@85004|Bifidobacteriales 201174|Actinobacteria S LytR cell envelope-related transcriptional attenuator - - - - - - - - - - - - LytR_C GGPLMPOG_00365 547043.BIFPSEUDO_03976 0.0 972.0 COG0617@1|root,COG0617@2|Bacteria,2GMT1@201174|Actinobacteria,4CYUH@85004|Bifidobacteriales 201174|Actinobacteria J Probable RNA and SrmB- binding site of polymerase A pcnA - 2.7.7.19,2.7.7.72 ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016,ko03019 - - - HD,PolyA_pol,PolyA_pol_RNAbd GGPLMPOG_00366 547043.BIFPSEUDO_03977 2.21e-156 438.0 COG0494@1|root,COG0494@2|Bacteria,2GWEB@201174|Actinobacteria,4CZAV@85004|Bifidobacteriales 201174|Actinobacteria L Belongs to the Nudix hydrolase family mutT4 - - - - - - - - - - - NUDIX GGPLMPOG_00367 547043.BIFPSEUDO_03978 0.0 1326.0 COG1361@1|root,COG1361@2|Bacteria,2I2GZ@201174|Actinobacteria,4D2V9@85004|Bifidobacteriales 201174|Actinobacteria M Conserved repeat domain - - - - - - - - - - - - - GGPLMPOG_00368 547043.BIFPSEUDO_03979 0.0 1058.0 COG0728@1|root,COG0728@2|Bacteria,2GKN0@201174|Actinobacteria,4CZ8M@85004|Bifidobacteriales 201174|Actinobacteria KLT MviN-like protein mviN GO:0003674,GO:0005215,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - ko:K03980 - - - - ko00000,ko01011,ko02000 2.A.66.4 - - MVIN GGPLMPOG_00369 547043.BIFPSEUDO_03980 0.0 1206.0 COG0728@1|root,COG0728@2|Bacteria,2GKN0@201174|Actinobacteria,4CZ8M@85004|Bifidobacteriales 201174|Actinobacteria KLT MviN-like protein - - - ko:K03980 - - - - ko00000,ko01011,ko02000 2.A.66.4 - - MVIN GGPLMPOG_00370 216816.GS08_00450 4.64e-16 77.4 COG1373@1|root,COG1373@2|Bacteria,2GK1Q@201174|Actinobacteria,4CZNQ@85004|Bifidobacteriales 201174|Actinobacteria S Domain of unknown function (DUF4143) - - - ko:K07133 - - - - ko00000 - - - AAA_14,DUF4143 GGPLMPOG_00371 547043.BIFPSEUDO_03983 1.85e-156 438.0 COG4502@1|root,COG4502@2|Bacteria,2IAHF@201174|Actinobacteria,4D0AG@85004|Bifidobacteriales 201174|Actinobacteria S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) - - - - - - - - - - - - NT5C GGPLMPOG_00373 547043.BIFPSEUDO_03986 5.61e-20 82.0 2B4NV@1|root,31XF4@2|Bacteria,2GYXI@201174|Actinobacteria,4D1TF@85004|Bifidobacteriales 201174|Actinobacteria S Psort location Extracellular, score 8.82 - - - - - - - - - - - - - GGPLMPOG_00374 547043.BIFPSEUDO_03987 9.1e-231 636.0 COG0492@1|root,COG0492@2|Bacteria,2GKD2@201174|Actinobacteria,4CYU9@85004|Bifidobacteriales 201174|Actinobacteria C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family trxB - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2 GGPLMPOG_00375 547043.BIFPSEUDO_03988 2.36e-268 741.0 COG1475@1|root,COG1475@2|Bacteria,2GNRN@201174|Actinobacteria,4CYUE@85004|Bifidobacteriales 201174|Actinobacteria K Belongs to the ParB family parB GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005694,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0060187,GO:0071944 - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc GGPLMPOG_00376 547043.BIFPSEUDO_03989 3.04e-221 611.0 COG1192@1|root,COG1192@2|Bacteria,2GMU7@201174|Actinobacteria,4CZ2D@85004|Bifidobacteriales 201174|Actinobacteria D CobQ CobB MinD ParA nucleotide binding domain protein parA - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 GGPLMPOG_00377 547043.BIFPSEUDO_03990 1.33e-167 471.0 COG0357@1|root,COG0357@2|Bacteria,2GM9Z@201174|Actinobacteria,4CZ29@85004|Bifidobacteriales 201174|Actinobacteria J Specifically methylates the N7 position of a guanine in 16S rRNA rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 - - - - ko00000,ko01000,ko03009,ko03036 - - - GidB GGPLMPOG_00378 547043.BIFPSEUDO_03991 2.6e-118 338.0 COG1847@1|root,COG1847@2|Bacteria,2GPZK@201174|Actinobacteria,4CYQQ@85004|Bifidobacteriales 201174|Actinobacteria S Putative single-stranded nucleic acids-binding domain jag - - ko:K06346 - - - - ko00000 - - - KH_4,R3H GGPLMPOG_00379 547043.BIFPSEUDO_03992 2.26e-244 671.0 COG0706@1|root,COG0706@2|Bacteria,2GJBU@201174|Actinobacteria,4CYZ2@85004|Bifidobacteriales 201174|Actinobacteria U Membrane protein insertase, YidC Oxa1 family yidC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP GGPLMPOG_00380 1435051.BMOU_1309 2.68e-19 78.6 COG0230@1|root,COG0230@2|Bacteria,2GQFY@201174|Actinobacteria,4D1EF@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the bacterial ribosomal protein bL34 family rpmH - - ko:K02914 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L34 GGPLMPOG_00381 547043.BIFPSEUDO_03996 0.0 1055.0 COG0593@1|root,COG0593@2|Bacteria,2GJKI@201174|Actinobacteria,4CZDW@85004|Bifidobacteriales 201174|Actinobacteria L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837 - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C GGPLMPOG_00382 547043.BIFPSEUDO_03998 1.09e-260 716.0 COG0592@1|root,COG0592@2|Bacteria,2GJK3@201174|Actinobacteria,4CZTV@85004|Bifidobacteriales 201174|Actinobacteria L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 GGPLMPOG_00383 547043.BIFPSEUDO_03999 1.35e-299 817.0 COG1195@1|root,COG1195@2|Bacteria,2GJCS@201174|Actinobacteria,4CZQT@85004|Bifidobacteriales 201174|Actinobacteria L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SMC_N GGPLMPOG_00384 547043.BIFPSEUDO_04000 1.01e-115 331.0 COG5512@1|root,COG5512@2|Bacteria,2GNQ4@201174|Actinobacteria,4D157@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF721) - - - - - - - - - - - - DUF721 GGPLMPOG_00385 547043.BIFPSEUDO_04002 0.0 1342.0 COG0187@1|root,COG0187@2|Bacteria,2GKGP@201174|Actinobacteria,4CZ47@85004|Bifidobacteriales 201174|Actinobacteria L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim GGPLMPOG_00386 547043.BIFPSEUDO_04003 0.0 1708.0 COG0188@1|root,COG0188@2|Bacteria,2GJ2Q@201174|Actinobacteria,4CYRP@85004|Bifidobacteriales 201174|Actinobacteria L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0008094,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034335,GO:0042623,GO:0061505,GO:0140097 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV GGPLMPOG_00387 547043.BIFPSEUDO_04004 5.13e-106 308.0 COG3266@1|root,COG3266@2|Bacteria,2GKZP@201174|Actinobacteria,4D0XB@85004|Bifidobacteriales 201174|Actinobacteria S Transmembrane domain of unknown function (DUF3566) - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - - - - - - - - - - DUF3566 GGPLMPOG_00388 547043.BIFPSEUDO_04005 0.0 890.0 COG0334@1|root,COG0334@2|Bacteria,2GKXG@201174|Actinobacteria,4CYTN@85004|Bifidobacteriales 201174|Actinobacteria E Belongs to the Glu Leu Phe Val dehydrogenases family gdhA GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.4 ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 - R00248 RC00006,RC02799 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,ELFV_dehydrog_N GGPLMPOG_00389 547043.BIFPSEUDO_04006 2.21e-97 285.0 COG1970@1|root,COG1970@2|Bacteria,2IQDN@201174|Actinobacteria,4D13A@85004|Bifidobacteriales 201174|Actinobacteria M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell mscL - - ko:K03282 - - - - ko00000,ko02000 1.A.22.1 - - MscL GGPLMPOG_00393 547043.BIFPSEUDO_04010 6.97e-142 404.0 COG1451@1|root,COG1451@2|Bacteria,2GMP6@201174|Actinobacteria,4CZF9@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function DUF45 - - - ko:K07043 - - - - ko00000 - - - DUF45 GGPLMPOG_00394 547043.BIFPSEUDO_04011 2.7e-238 655.0 COG0039@1|root,COG0039@2|Bacteria,2IASS@201174|Actinobacteria,4CZRT@85004|Bifidobacteriales 201174|Actinobacteria C Belongs to the LDH MDH superfamily ldh - 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 - R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N GGPLMPOG_00395 547043.BIFPSEUDO_04012 6.78e-306 835.0 COG1253@1|root,COG1253@2|Bacteria,2GKN5@201174|Actinobacteria,4CZKA@85004|Bifidobacteriales 201174|Actinobacteria P Transporter associated domain - - - ko:K03699 - - - - ko00000,ko02042 - - - CBS,CorC_HlyC,DUF21 GGPLMPOG_00396 547043.BIFPSEUDO_04013 1.67e-153 432.0 COG0288@1|root,COG0288@2|Bacteria,2GT5H@201174|Actinobacteria,4D06V@85004|Bifidobacteriales 201174|Actinobacteria P Reversible hydration of carbon dioxide cah - 4.2.1.1 ko:K01673 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Pro_CA GGPLMPOG_00398 547043.BIFPSEUDO_04016 0.0 1823.0 COG2352@1|root,COG2352@2|Bacteria,2GKDB@201174|Actinobacteria,4CZS0@85004|Bifidobacteriales 201174|Actinobacteria H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle ppc GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00168,M00170,M00171,M00172,M00173,M00346,M00374 R00345 RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPcase GGPLMPOG_00399 547043.BIFPSEUDO_04017 0.0 1195.0 COG2966@1|root,COG3610@1|root,COG2966@2|Bacteria,COG3610@2|Bacteria,2HZ8C@201174|Actinobacteria,4CYR2@85004|Bifidobacteriales 201174|Actinobacteria S Threonine/Serine exporter, ThrE - - - - - - - - - - - - ThrE,ThrE_2 GGPLMPOG_00400 547043.BIFPSEUDO_04018 0.0 1030.0 COG0591@1|root,COG0591@2|Bacteria,2I041@201174|Actinobacteria,4CZS2@85004|Bifidobacteriales 201174|Actinobacteria E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - ko:K11928 - - - - ko00000,ko02000 2.A.21.2 - - SSF GGPLMPOG_00401 547043.BIFPSEUDO_04019 2.64e-262 719.0 COG0180@1|root,COG0180@2|Bacteria,2GJ9A@201174|Actinobacteria,4CYXM@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the class-I aminoacyl-tRNA synthetase family trpS - 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b GGPLMPOG_00402 547043.BIFPSEUDO_04020 1.49e-64 199.0 2EGRW@1|root,32FNP@2|Bacteria,2HZNH@201174|Actinobacteria,4D120@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF3073) - - - - - - - - - - - - DUF3073 GGPLMPOG_00403 547043.BIFPSEUDO_04021 1.1e-82 245.0 COG3255@1|root,COG3255@2|Bacteria,2IQBF@201174|Actinobacteria,4D10H@85004|Bifidobacteriales 201174|Actinobacteria I Sterol carrier protein - - - - - - - - - - - - MDMPI_C,MDMPI_N GGPLMPOG_00404 547043.BIFPSEUDO_04022 0.0 1640.0 COG0058@1|root,COG0058@2|Bacteria,2GIVZ@201174|Actinobacteria,4CZ3V@85004|Bifidobacteriales 201174|Actinobacteria G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties glgP - 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - Phosphorylase GGPLMPOG_00405 547043.BIFPSEUDO_04023 7.68e-47 150.0 2BFAJ@1|root,3293I@2|Bacteria,2ISGB@201174|Actinobacteria,4D185@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_00406 547043.BIFPSEUDO_04025 4.68e-190 527.0 COG0705@1|root,COG0705@2|Bacteria,2GJYG@201174|Actinobacteria,4CZJ0@85004|Bifidobacteriales 201174|Actinobacteria S Rhomboid family gluP - 3.4.21.105 ko:K19225 - - - - ko00000,ko01000,ko01002 - - - Rhomboid,zf-B_box GGPLMPOG_00407 547043.BIFPSEUDO_04027 4.68e-306 837.0 COG0742@1|root,COG0742@2|Bacteria,2HZAY@201174|Actinobacteria,4CZEU@85004|Bifidobacteriales 201174|Actinobacteria L ribosomal rna small subunit methyltransferase - - - - - - - - - - - - Cons_hypoth95,Methyltransf_15,PCMT GGPLMPOG_00408 547043.BIFPSEUDO_04029 2.28e-90 267.0 2E4NY@1|root,32ZHR@2|Bacteria,2GQPW@201174|Actinobacteria,4D0ZH@85004|Bifidobacteriales 201174|Actinobacteria D Involved in cell division crgA - - - - - - - - - - - CrgA GGPLMPOG_00409 547043.BIFPSEUDO_04030 1.12e-182 509.0 COG3879@1|root,COG3879@2|Bacteria,2GJ9Y@201174|Actinobacteria,4CZ1A@85004|Bifidobacteriales 201174|Actinobacteria S Bacterial protein of unknown function (DUF881) - - - - - - - - - - - - DUF881 GGPLMPOG_00410 547043.BIFPSEUDO_04031 3.89e-266 728.0 COG3764@1|root,COG3764@2|Bacteria,2GKT6@201174|Actinobacteria,4CYZ5@85004|Bifidobacteriales 201174|Actinobacteria M Sortase family srtB - 3.4.22.70 ko:K07284 - - - - ko00000,ko01000,ko01002,ko01011 - - - Sortase GGPLMPOG_00411 547043.BIFPSEUDO_04033 2.05e-148 418.0 COG0512@1|root,COG0512@2|Bacteria,2GJUX@201174|Actinobacteria,4D09E@85004|Bifidobacteriales 201174|Actinobacteria EH para-aminobenzoate synthase glutamine amidotransferase component II trpG GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85,4.1.3.27 ko:K01658,ko:K01664 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986,R01716 RC00010,RC01418,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - GATase GGPLMPOG_00412 566552.BIFCAT_00075 0.0 1234.0 COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4CZFU@85004|Bifidobacteriales 201174|Actinobacteria KLT Protein tyrosine kinase pknB GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase GGPLMPOG_00413 566552.BIFCAT_00076 4.29e-227 625.0 COG0515@1|root,COG0515@2|Bacteria,2GMPZ@201174|Actinobacteria,4CYUK@85004|Bifidobacteriales 201174|Actinobacteria T Protein tyrosine kinase pknA - 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase GGPLMPOG_00414 547043.BIFPSEUDO_04037 0.0 927.0 COG0768@1|root,COG0768@2|Bacteria,2GJUQ@201174|Actinobacteria,4CYTI@85004|Bifidobacteriales 201174|Actinobacteria M penicillin-binding protein pbpA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K05364 ko00550,map00550 - R04519 RC00005,RC00049 ko00000,ko00001,ko01011 - - - Transpeptidase GGPLMPOG_00415 547043.BIFPSEUDO_04038 0.0 947.0 COG0772@1|root,COG0772@2|Bacteria,2GJTI@201174|Actinobacteria,4CZ67@85004|Bifidobacteriales 201174|Actinobacteria D Belongs to the SEDS family rodA GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136 - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE GGPLMPOG_00416 547043.BIFPSEUDO_04039 0.0 886.0 COG0631@1|root,COG0631@2|Bacteria,2GJ3M@201174|Actinobacteria,4CZDN@85004|Bifidobacteriales 201174|Actinobacteria T Sigma factor PP2C-like phosphatases pstP GO:0000287,GO:0001932,GO:0001933,GO:0003674,GO:0003824,GO:0004647,GO:0004721,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006469,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009892,GO:0009987,GO:0010563,GO:0010605,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019220,GO:0019222,GO:0019538,GO:0030145,GO:0030312,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0032268,GO:0032269,GO:0033673,GO:0036211,GO:0042325,GO:0042326,GO:0042578,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043392,GO:0043412,GO:0043549,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0045859,GO:0045936,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051098,GO:0051100,GO:0051101,GO:0051171,GO:0051172,GO:0051174,GO:0051246,GO:0051248,GO:0051338,GO:0051348,GO:0060255,GO:0065007,GO:0065009,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C,PP2C_2 GGPLMPOG_00417 547043.BIFPSEUDO_04040 1.54e-99 291.0 COG1716@1|root,COG1716@2|Bacteria,2GKA7@201174|Actinobacteria,4D0RN@85004|Bifidobacteriales 201174|Actinobacteria T Inner membrane component of T3SS, cytoplasmic domain fhaB GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944 - - - - - - - - - - FHA,Yop-YscD_cpl GGPLMPOG_00418 547043.BIFPSEUDO_04041 2.6e-168 470.0 COG1716@1|root,COG1716@2|Bacteria,2GNU2@201174|Actinobacteria,4CYUI@85004|Bifidobacteriales 201174|Actinobacteria T Protein of unknown function (DUF2662) fhaA GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363 - - - - - - - - - - DUF3662,FHA,Yop-YscD_cpl GGPLMPOG_00419 547043.BIFPSEUDO_04042 0.0 1484.0 COG1506@1|root,COG1506@2|Bacteria,2GJ6A@201174|Actinobacteria,4CZAE@85004|Bifidobacteriales 201174|Actinobacteria E Dipeptidyl peptidase IV (DPP IV) N-terminal region pepX - 3.4.14.5 ko:K01278 ko04974,map04974 - - - ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 - - - DPPIV_N,PD40,Peptidase_S9 GGPLMPOG_00420 547043.BIFPSEUDO_04043 5.42e-293 801.0 COG4585@1|root,COG4585@2|Bacteria,2II1W@201174|Actinobacteria,4D0V3@85004|Bifidobacteriales 201174|Actinobacteria T Histidine kinase - - - - - - - - - - - - HisKA_3 GGPLMPOG_00421 547043.BIFPSEUDO_04044 6.6e-147 414.0 COG2197@1|root,COG2197@2|Bacteria,2IF55@201174|Actinobacteria,4D00S@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg GGPLMPOG_00422 547043.BIFPSEUDO_04046 2.35e-246 677.0 COG2267@1|root,COG2267@2|Bacteria,2HZ9U@201174|Actinobacteria,4CZ5E@85004|Bifidobacteriales 201174|Actinobacteria I Serine aminopeptidase, S33 pldB - 3.1.1.5 ko:K01048 ko00564,map00564 - - - ko00000,ko00001,ko01000 - - - Hydrolase_4 GGPLMPOG_00423 566552.BIFCAT_00087 7.98e-209 580.0 COG0697@1|root,COG0697@2|Bacteria,2HZCH@201174|Actinobacteria,4CZRZ@85004|Bifidobacteriales 201174|Actinobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA GGPLMPOG_00424 78346.BRUM_1765 4.19e-111 323.0 COG2910@1|root,COG2910@2|Bacteria,2GK2P@201174|Actinobacteria,4D0A4@85004|Bifidobacteriales 201174|Actinobacteria S NAD(P)H-binding - - - ko:K07118 - - - - ko00000 - - - NAD_binding_10 GGPLMPOG_00425 78346.BRUM_1764 1.76e-57 181.0 COG1733@1|root,COG1733@2|Bacteria,2IQNN@201174|Actinobacteria,4D13S@85004|Bifidobacteriales 201174|Actinobacteria K HxlR-like helix-turn-helix - - - - - - - - - - - - HxlR GGPLMPOG_00427 547043.BIFPSEUDO_04051 0.0 926.0 COG0343@1|root,COG0343@2|Bacteria,2GMWY@201174|Actinobacteria,4CZNX@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) tgt - 2.4.2.29 ko:K00773 - - R03789,R10209 RC00063 ko00000,ko01000,ko03016 - - - TGT GGPLMPOG_00428 566552.BIFCAT_00092 0.0 1006.0 COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4CZAP@85004|Bifidobacteriales 201174|Actinobacteria O Domain present in PSD-95, Dlg, and ZO-1/2. degP - - ko:K08372 ko02020,map02020 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ_2,Trypsin_2 GGPLMPOG_00429 566552.BIFCAT_00094 0.0 1433.0 COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4CZ4F@85004|Bifidobacteriales 201174|Actinobacteria P E1-E2 ATPase - - 3.6.3.4,3.6.3.54 ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,Hemerythrin,Hydrolase GGPLMPOG_00430 547043.BIFPSEUDO_04054 9.96e-244 669.0 COG0252@1|root,COG0252@2|Bacteria,2HUB2@201174|Actinobacteria,4CZY6@85004|Bifidobacteriales 201174|Actinobacteria EJ Asparaginase ansA - 3.5.1.1 ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 - R00485 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Asparaginase GGPLMPOG_00431 1435051.BMOU_1361 0.0 879.0 COG1113@1|root,COG1113@2|Bacteria,2GJ0X@201174|Actinobacteria,4CZ4X@85004|Bifidobacteriales 201174|Actinobacteria E aromatic amino acid transport protein AroP K03293 - - - ko:K11738 - - - - ko00000,ko02000 2.A.3.1.8 - - AA_permease GGPLMPOG_00432 547043.BIFPSEUDO_04057 0.0 956.0 COG0493@1|root,COG0493@2|Bacteria,2GJ4A@201174|Actinobacteria,4CZIT@85004|Bifidobacteriales 201174|Actinobacteria C Pyridine nucleotide-disulphide oxidoreductase fprA - 1.18.1.2,1.19.1.1 ko:K00528 - - R10159 - ko00000,ko01000 - - - Pyr_redox_2 GGPLMPOG_00433 547043.BIFPSEUDO_04058 1.69e-257 706.0 COG0501@1|root,COG0501@2|Bacteria,2GMJF@201174|Actinobacteria,4CYVY@85004|Bifidobacteriales 201174|Actinobacteria O Belongs to the peptidase M48B family htpX GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - ko:K03799 - M00743 - - ko00000,ko00002,ko01000,ko01002 - - - Peptidase_M48 GGPLMPOG_00435 78346.BRUM_0435 5.7e-253 699.0 COG1476@1|root,COG1476@2|Bacteria,2IBHI@201174|Actinobacteria,4CZ2T@85004|Bifidobacteriales 201174|Actinobacteria K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3 GGPLMPOG_00436 547043.BIFPSEUDO_04062 2.01e-218 603.0 COG0697@1|root,COG0697@2|Bacteria,2GM6M@201174|Actinobacteria,4CZPP@85004|Bifidobacteriales 201174|Actinobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA GGPLMPOG_00437 566552.BIFCAT_00100 0.0 1254.0 COG1511@1|root,COG1511@2|Bacteria,2GKEM@201174|Actinobacteria,4CZ2A@85004|Bifidobacteriales 201174|Actinobacteria S YhgE Pip domain protein - - - ko:K01421 - - - - ko00000 - - - ABC2_membrane,ABC2_membrane_3,DUF3533 GGPLMPOG_00438 1680.BADO_0052 0.0 1504.0 COG1511@1|root,COG1511@2|Bacteria,2GKEM@201174|Actinobacteria,4CZ9R@85004|Bifidobacteriales 201174|Actinobacteria S YhgE Pip domain protein - - - ko:K01421 - - - - ko00000 - - - ABC2_membrane_3,DUF3533 GGPLMPOG_00439 547043.BIFPSEUDO_04065 7.78e-265 726.0 COG0191@1|root,COG0191@2|Bacteria,2GM5P@201174|Actinobacteria,4CZJI@85004|Bifidobacteriales 201174|Actinobacteria G Fructose-bisphosphate aldolase class-II fbaA - 4.1.2.13 ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 - - - F_bP_aldolase GGPLMPOG_00440 547043.BIFPSEUDO_04067 0.0 864.0 COG0104@1|root,COG0104@2|Bacteria,2GMP4@201174|Actinobacteria,4CZ0U@85004|Bifidobacteriales 201174|Actinobacteria F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - - Adenylsucc_synt GGPLMPOG_00441 216816.GS08_00505 0.0 975.0 COG0038@1|root,COG0569@1|root,COG0038@2|Bacteria,COG0569@2|Bacteria,2GPPN@201174|Actinobacteria,4CZQR@85004|Bifidobacteriales 201174|Actinobacteria P Voltage gated chloride channel - - - ko:K03281 - - - - ko00000 2.A.49 - - TrkA_C,Voltage_CLC GGPLMPOG_00442 547043.BIFPSEUDO_04069 2.09e-247 685.0 COG0239@1|root,COG0239@2|Bacteria,2IC26@201174|Actinobacteria,4D0RK@85004|Bifidobacteriales 201174|Actinobacteria U Important for reducing fluoride concentration in the cell, thus reducing its toxicity crcB - - ko:K06199 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CRCB GGPLMPOG_00443 547043.BIFPSEUDO_04070 1.95e-85 252.0 COG0239@1|root,COG0239@2|Bacteria,2IC26@201174|Actinobacteria,4D14T@85004|Bifidobacteriales 201174|Actinobacteria U Important for reducing fluoride concentration in the cell, thus reducing its toxicity crcB - - ko:K06199 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CRCB GGPLMPOG_00444 566552.BIFCAT_00107 6.92e-41 134.0 COG0683@1|root,COG0683@2|Bacteria,2GM00@201174|Actinobacteria,4CZSH@85004|Bifidobacteriales 201174|Actinobacteria E Receptor family ligand binding region livK - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 GGPLMPOG_00445 547043.BIFPSEUDO_04073 5.58e-249 684.0 COG1609@1|root,COG1609@2|Bacteria,2GMHV@201174|Actinobacteria,4CZ3G@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn _helix lactose operon repressor - - - ko:K03484 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 GGPLMPOG_00446 566552.BIFCAT_00110 0.0 1015.0 COG0366@1|root,COG0366@2|Bacteria,2GNEC@201174|Actinobacteria,4CZ4T@85004|Bifidobacteriales 201174|Actinobacteria G Domain of unknown function (DUF1964) gtfA - 2.4.1.7 ko:K00690 ko00500,map00500 - R00803 RC00028 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,DUF1964 GGPLMPOG_00447 547043.BIFPSEUDO_04075 9.39e-149 419.0 COG5578@1|root,COG5578@2|Bacteria,2IHJ3@201174|Actinobacteria,4D0SU@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function, DUF624 - - - - - - - - - - - - DUF624 GGPLMPOG_00448 547043.BIFPSEUDO_04076 0.0 1298.0 COG0366@1|root,COG0366@2|Bacteria,2GIV1@201174|Actinobacteria,4D02P@85004|Bifidobacteriales 201174|Actinobacteria G Alpha-amylase domain - - 2.4.1.4,3.2.1.1,3.2.1.20,5.4.99.16 ko:K01187,ko:K05341,ko:K05343 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R01557,R01823,R02108,R02112,R06087,R06088,R11262 RC00028,RC00049,RC00077,RC01816 ko00000,ko00001,ko01000 - GH13,GH31 - Alpha-amylase GGPLMPOG_00449 547043.BIFPSEUDO_04077 6.08e-312 849.0 COG2182@1|root,COG2182@2|Bacteria,2I5YS@201174|Actinobacteria,4D0AK@85004|Bifidobacteriales 201174|Actinobacteria G Bacterial extracellular solute-binding protein - - - ko:K10117 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - SBP_bac_8 GGPLMPOG_00450 547043.BIFPSEUDO_04078 8.78e-210 580.0 COG1175@1|root,COG1175@2|Bacteria,2IB68@201174|Actinobacteria,4D00T@85004|Bifidobacteriales 201174|Actinobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K10118 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - BPD_transp_1 GGPLMPOG_00451 547043.BIFPSEUDO_04079 2.58e-193 537.0 COG0395@1|root,COG0395@2|Bacteria,2GJNN@201174|Actinobacteria,4CZ44@85004|Bifidobacteriales 201174|Actinobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02026,ko:K10119 ko02010,map02010 M00196,M00207 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.28 - - BPD_transp_1 GGPLMPOG_00452 547043.BIFPSEUDO_04081 0.0 1010.0 COG2211@1|root,COG2211@2|Bacteria,2GJZG@201174|Actinobacteria,4CZ93@85004|Bifidobacteriales 201174|Actinobacteria G Transporter major facilitator family protein scrT - - - - - - - - - - - MFS_1,MFS_2 GGPLMPOG_00453 547043.BIFPSEUDO_04084 0.0 879.0 COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria,4CYY8@85004|Bifidobacteriales 201174|Actinobacteria EGP Sugar (and other) transporter - - - - - - - - - - - - MFS_1,Sugar_tr GGPLMPOG_00454 547043.BIFPSEUDO_04085 2.65e-259 710.0 COG0059@1|root,COG0059@2|Bacteria,2GKXA@201174|Actinobacteria,4CZBR@85004|Bifidobacteriales 201174|Actinobacteria H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate ilvC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008677,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 1.1.1.86 ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R03051,R04439,R04440,R05068,R05069,R05071 RC00726,RC00836,RC00837,RC01726 ko00000,ko00001,ko00002,ko01000 - - - IlvC,IlvN GGPLMPOG_00455 547043.BIFPSEUDO_04087 3.55e-258 706.0 COG0059@1|root,COG0059@2|Bacteria,2GKXA@201174|Actinobacteria,4CZBR@85004|Bifidobacteriales 201174|Actinobacteria H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate ilvC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008677,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 1.1.1.86 ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R03051,R04439,R04440,R05068,R05069,R05071 RC00726,RC00836,RC00837,RC01726 ko00000,ko00001,ko00002,ko01000 - - - IlvC,IlvN GGPLMPOG_00456 547043.BIFPSEUDO_04089 0.0 1238.0 COG2755@1|root,COG2755@2|Bacteria,2I2FJ@201174|Actinobacteria,4D2US@85004|Bifidobacteriales 201174|Actinobacteria E Carbohydrate esterase, sialic acid-specific acetylesterase - - 3.1.1.53 ko:K05970 - - - - ko00000,ko01000 - - - SASA GGPLMPOG_00457 547043.BIFPSEUDO_04090 7.88e-51 161.0 COG3250@1|root,COG3250@2|Bacteria,2GM69@201174|Actinobacteria,4D09M@85004|Bifidobacteriales 201174|Actinobacteria G beta-mannosidase - - 3.2.1.25 ko:K01192 ko00511,ko04142,map00511,map04142 - - - ko00000,ko00001,ko01000 - - - Glyco_hydro_2 GGPLMPOG_00458 547043.BIFPSEUDO_04091 3.85e-236 650.0 COG1609@1|root,COG1609@2|Bacteria,2GJHF@201174|Actinobacteria,4CZCC@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn _helix lactose operon repressor - - - - - - - - - - - - LacI,Peripla_BP_3 GGPLMPOG_00459 1680.BADO_0080 4.62e-15 73.9 COG5578@1|root,COG5578@2|Bacteria,2IGDH@201174|Actinobacteria,4D0WB@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function, DUF624 - - - - - - - - - - - - DUF624 GGPLMPOG_00460 547043.BIFPSEUDO_04093 0.0 932.0 COG1113@1|root,COG1113@2|Bacteria,2GJ0X@201174|Actinobacteria,4CZ4X@85004|Bifidobacteriales 201174|Actinobacteria E aromatic amino acid transport protein AroP K03293 aroP - - ko:K03293,ko:K11732 - - - - ko00000,ko02000 2.A.3.1,2.A.3.1.1 - - AA_permease GGPLMPOG_00461 547043.BIFPSEUDO_04095 0.0 1755.0 COG0577@1|root,COG1511@1|root,COG0577@2|Bacteria,COG1511@2|Bacteria,2I2FK@201174|Actinobacteria,4CZJR@85004|Bifidobacteriales 201174|Actinobacteria V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX GGPLMPOG_00462 547043.BIFPSEUDO_04096 3.48e-310 851.0 COG0475@1|root,COG0475@2|Bacteria,2GIRC@201174|Actinobacteria,4CZGM@85004|Bifidobacteriales 201174|Actinobacteria P Sodium/hydrogen exchanger family - - - - - - - - - - - - Na_H_Exchanger GGPLMPOG_00463 547043.BIFPSEUDO_04098 1.4e-100 292.0 2DNNA@1|root,32Y8E@2|Bacteria,2ISEY@201174|Actinobacteria,4D0R1@85004|Bifidobacteriales 201174|Actinobacteria S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - - GGPLMPOG_00464 547043.BIFPSEUDO_04099 5.55e-245 676.0 COG3764@1|root,COG3764@2|Bacteria,2GNWT@201174|Actinobacteria,4CZMM@85004|Bifidobacteriales 201174|Actinobacteria M Sortase family - - 3.4.22.70 ko:K07284 - - - - ko00000,ko01000,ko01002,ko01011 - - - Sortase GGPLMPOG_00465 547043.BIFPSEUDO_04100 0.0 1533.0 COG2304@1|root,COG4932@1|root,COG2304@2|Bacteria,COG4932@2|Bacteria,2I2FM@201174|Actinobacteria,4CZ4I@85004|Bifidobacteriales 201174|Actinobacteria M domain protein - - - - - - - - - - - - Cna_B,FctA,PA14,VWA_2 GGPLMPOG_00466 547043.BIFPSEUDO_04102 3.46e-278 771.0 COG4932@1|root,COG4932@2|Bacteria,2GP68@201174|Actinobacteria,4CZV4@85004|Bifidobacteriales 201174|Actinobacteria M LPXTG cell wall anchor motif - - - - - - - - - - - - GramPos_pilinBB,Gram_pos_anchor GGPLMPOG_00467 547043.BIFPSEUDO_04104 6.5e-115 330.0 2ASX6@1|root,31ICR@2|Bacteria,2IHV1@201174|Actinobacteria,4D0WZ@85004|Bifidobacteriales 201174|Actinobacteria S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - - GGPLMPOG_00468 547043.BIFPSEUDO_04106 0.0 949.0 COG1113@1|root,COG1113@2|Bacteria,2GJ0X@201174|Actinobacteria,4CZAY@85004|Bifidobacteriales 201174|Actinobacteria E Amino acid permease - - - ko:K03293 - - - - ko00000 2.A.3.1 - - AA_permease GGPLMPOG_00469 547043.BIFPSEUDO_04107 1.79e-214 592.0 COG2022@1|root,COG2022@2|Bacteria,2GM62@201174|Actinobacteria,4CZ4A@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S thiG - 2.8.1.10 ko:K03149 ko00730,ko01100,map00730,map01100 - R10247 RC03096,RC03097,RC03461 ko00000,ko00001,ko01000 - - - ThiG,ThiS GGPLMPOG_00470 547043.BIFPSEUDO_04108 2.91e-166 465.0 COG0476@1|root,COG0476@2|Bacteria,2GJB6@201174|Actinobacteria,4D06G@85004|Bifidobacteriales 201174|Actinobacteria H ThiF family thiF - 2.7.7.73 ko:K03148 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07459 RC00043 ko00000,ko00001,ko01000 - - - ThiF GGPLMPOG_00471 547043.BIFPSEUDO_04109 4.87e-37 124.0 COG2104@1|root,COG2104@2|Bacteria,2GSKM@201174|Actinobacteria,4D1GS@85004|Bifidobacteriales 201174|Actinobacteria H ThiS family thiS - - ko:K03154 ko04122,map04122 - - - ko00000,ko00001 - - - ThiS GGPLMPOG_00472 566552.BIFCAT_00134 6.96e-234 646.0 COG0667@1|root,COG0667@2|Bacteria,2GJ6R@201174|Actinobacteria,4CZ9P@85004|Bifidobacteriales 201174|Actinobacteria C Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red GGPLMPOG_00473 1435051.BMOU_1440 3.21e-75 229.0 COG1846@1|root,COG1846@2|Bacteria,2IMKE@201174|Actinobacteria,4CYZZ@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn_helix multiple antibiotic resistance protein - - - - - - - - - - - - HTH_34,MarR GGPLMPOG_00474 78345.BMERY_0521 0.0 993.0 COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4CYYV@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter, ATP-binding protein - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran GGPLMPOG_00475 78345.BMERY_0522 0.0 1067.0 COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4CZTU@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter transmembrane region - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran GGPLMPOG_00476 1435051.BMOU_1444 8.55e-148 426.0 COG1477@1|root,COG1477@2|Bacteria,2H8YU@201174|Actinobacteria,4CZW7@85004|Bifidobacteriales 201174|Actinobacteria H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein - - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE GGPLMPOG_00477 1435051.BMOU_1445 3.31e-302 828.0 COG2211@1|root,COG2211@2|Bacteria,2HZ98@201174|Actinobacteria,4CZ0N@85004|Bifidobacteriales 201174|Actinobacteria G MFS/sugar transport protein - - - - - - - - - - - - MFS_2 GGPLMPOG_00478 547043.BIFPSEUDO_04117 0.0 1029.0 COG0672@1|root,COG0672@2|Bacteria,2GJ22@201174|Actinobacteria,4D01C@85004|Bifidobacteriales 201174|Actinobacteria P Iron permease FTR1 family - - - ko:K07243 - - - - ko00000,ko02000 2.A.108.1,2.A.108.2 - - FTR1 GGPLMPOG_00479 547043.BIFPSEUDO_04118 7.78e-133 379.0 COG3470@1|root,COG3470@2|Bacteria,2GNAD@201174|Actinobacteria,4CZCG@85004|Bifidobacteriales 201174|Actinobacteria P Fe2+ transport protein - - - ko:K07230 - - - - ko00000,ko02000 2.A.108.2.10,2.A.108.2.4,2.A.108.2.9 - - Iron_transport GGPLMPOG_00480 547043.BIFPSEUDO_04121 1.62e-293 802.0 COG4393@1|root,COG4393@2|Bacteria,2GMS6@201174|Actinobacteria,4CZ19@85004|Bifidobacteriales 201174|Actinobacteria S Predicted membrane protein (DUF2318) - - - - - - - - - - - - DUF2318 GGPLMPOG_00481 566552.BIFCAT_00144 3.43e-287 789.0 COG0577@1|root,COG0577@2|Bacteria,2I91N@201174|Actinobacteria,4CZGK@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter permease - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD GGPLMPOG_00483 547043.BIFPSEUDO_04123 1.91e-267 736.0 COG0577@1|root,COG0577@2|Bacteria,2GIRW@201174|Actinobacteria,4CZEZ@85004|Bifidobacteriales 201174|Actinobacteria V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX GGPLMPOG_00484 566552.BIFCAT_00146 5.66e-191 530.0 COG1136@1|root,COG1136@2|Bacteria,2GK3I@201174|Actinobacteria,4CYTA@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter, ATP-binding protein - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran GGPLMPOG_00485 547043.BIFPSEUDO_04125 4.79e-103 301.0 COG3976@1|root,COG3976@2|Bacteria,2IQ4E@201174|Actinobacteria,4D0YM@85004|Bifidobacteriales 201174|Actinobacteria S FMN_bind - - - - - - - - - - - - FMN_bind GGPLMPOG_00486 566552.BIFCAT_00148 1.85e-118 342.0 COG1309@1|root,COG1309@2|Bacteria,2HZI8@201174|Actinobacteria,4D0IS@85004|Bifidobacteriales 201174|Actinobacteria K Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - TetR_C_9,TetR_N GGPLMPOG_00487 547043.BIFPSEUDO_04127 0.0 1038.0 COG1511@1|root,COG1511@2|Bacteria,2GKEM@201174|Actinobacteria,4CZ2A@85004|Bifidobacteriales 201174|Actinobacteria S YhgE Pip domain protein - - - ko:K01421 - - - - ko00000 - - - ABC2_membrane,ABC2_membrane_3,DUF3533 GGPLMPOG_00488 547043.BIFPSEUDO_04128 0.0 1488.0 COG1511@1|root,COG1511@2|Bacteria,2GKEM@201174|Actinobacteria,4CZ9R@85004|Bifidobacteriales 201174|Actinobacteria S YhgE Pip domain protein - - - ko:K01421 - - - - ko00000 - - - ABC2_membrane,ABC2_membrane_3 GGPLMPOG_00489 547043.BIFPSEUDO_04129 8.57e-289 790.0 COG4905@1|root,COG4905@2|Bacteria,2IBSV@201174|Actinobacteria,4D05G@85004|Bifidobacteriales 201174|Actinobacteria S Putative ABC-transporter type IV - - - - - - - - - - - - ABC_trans_CmpB GGPLMPOG_00490 547043.BIFPSEUDO_04130 2.38e-50 159.0 COG0695@1|root,COG0695@2|Bacteria,2IRCP@201174|Actinobacteria,4D17U@85004|Bifidobacteriales 201174|Actinobacteria O Glutaredoxin nrdH - - ko:K06191 - - - - ko00000 - - - Glutaredoxin GGPLMPOG_00491 518635.BIFANG_02039 0.0 966.0 COG2247@1|root,COG2247@2|Bacteria,2H1NZ@201174|Actinobacteria,4D23P@85004|Bifidobacteriales 201174|Actinobacteria M cell wall binding repeat - - - - - - - - - - - - - GGPLMPOG_00492 78346.BRUM_1843 1.76e-29 115.0 2DRQW@1|root,33CPG@2|Bacteria,2IR94@201174|Actinobacteria,4D198@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_00493 78344.BIGA_1602 2.64e-103 305.0 COG0582@1|root,COG0582@2|Bacteria,2I2P9@201174|Actinobacteria,4D2X6@85004|Bifidobacteriales 201174|Actinobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase GGPLMPOG_00494 547043.BIFPSEUDO_03279 1.68e-60 186.0 COG2963@1|root,COG2963@2|Bacteria,2IRD7@201174|Actinobacteria,4D16D@85004|Bifidobacteriales 201174|Actinobacteria L Psort location Cytoplasmic, score 8.87 - - - ko:K07483 - - - - ko00000 - - - HTH_Tnp_1 GGPLMPOG_00495 547043.BIFPSEUDO_03278 1.29e-162 458.0 COG2801@1|root,COG2801@2|Bacteria,2GKDY@201174|Actinobacteria,4CZQK@85004|Bifidobacteriales 201174|Actinobacteria L Integrase core domain - - - ko:K07483 - - - - ko00000 - - - HTH_21,HTH_Tnp_1,rve,rve_3 GGPLMPOG_00496 547043.BIFPSEUDO_04129 5.79e-43 151.0 COG4905@1|root,COG4905@2|Bacteria,2IBSV@201174|Actinobacteria,4D05G@85004|Bifidobacteriales 201174|Actinobacteria S Putative ABC-transporter type IV - - - - - - - - - - - - ABC_trans_CmpB GGPLMPOG_00498 1437610.BREU_0068 0.0 897.0 COG2060@1|root,COG2060@2|Bacteria,2GK51@201174|Actinobacteria,4CZK2@85004|Bifidobacteriales 201174|Actinobacteria P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane kdpA GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 ko:K01546 ko02020,map02020 - - - ko00000,ko00001,ko01000 3.A.3.7 - - KdpA GGPLMPOG_00499 1437610.BREU_0067 0.0 1172.0 COG2216@1|root,COG2216@2|Bacteria,2GIWT@201174|Actinobacteria,4CYPU@85004|Bifidobacteriales 201174|Actinobacteria P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system kdpB - 3.6.3.12 ko:K01547 ko02020,map02020 - - - ko00000,ko00001,ko01000 3.A.3.7 - - E1-E2_ATPase,Hydrolase GGPLMPOG_00500 1437610.BREU_0066 1.36e-89 268.0 COG2156@1|root,COG2156@2|Bacteria,2GK75@201174|Actinobacteria,4D1H0@85004|Bifidobacteriales 201174|Actinobacteria P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex kdpC GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 ko:K01548 ko02020,map02020 - - - ko00000,ko00001,ko01000 3.A.3.7 - - KdpC GGPLMPOG_00501 1437609.BCAL_0240 0.0 1112.0 COG0642@1|root,COG2205@2|Bacteria,2GJKC@201174|Actinobacteria,4CZEP@85004|Bifidobacteriales 201174|Actinobacteria T Osmosensitive K+ channel His kinase sensor domain kdpD - 2.7.13.3 ko:K07646 ko02020,map02020 M00454 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - DUF4118,HATPase_c,HisKA,KdpD,Usp GGPLMPOG_00502 1437610.BREU_0063 2.73e-136 389.0 COG0745@1|root,COG0745@2|Bacteria,2GJ2N@201174|Actinobacteria,4CZDR@85004|Bifidobacteriales 201174|Actinobacteria KT Transcriptional regulatory protein, C terminal kdpE - - ko:K02483,ko:K07667 ko02020,ko02024,map02020,map02024 M00454 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C GGPLMPOG_00503 1680.BADO_0118 5.23e-45 145.0 COG0695@1|root,COG0695@2|Bacteria,2IRCP@201174|Actinobacteria,4D17U@85004|Bifidobacteriales 201174|Actinobacteria O Glutaredoxin nrdH - - ko:K06191 - - - - ko00000 - - - Glutaredoxin GGPLMPOG_00505 566552.BIFCAT_00154 0.0 1053.0 COG4690@1|root,COG4690@2|Bacteria,2GM80@201174|Actinobacteria,4CYT0@85004|Bifidobacteriales 201174|Actinobacteria E Peptidase family C69 - - - ko:K08659 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C69 GGPLMPOG_00506 566552.BIFCAT_00156 1.37e-249 684.0 COG0463@1|root,COG0463@2|Bacteria,2GMDK@201174|Actinobacteria,4CZIS@85004|Bifidobacteriales 201174|Actinobacteria M Glycosyltransferase like family 2 - - 2.7.8.12 ko:K09809 - - - - ko00000,ko01000 - - - Glycos_transf_2 GGPLMPOG_00507 547043.BIFPSEUDO_02895 1.73e-145 415.0 COG1309@1|root,COG1309@2|Bacteria,2GMBW@201174|Actinobacteria,4CYUD@85004|Bifidobacteriales 201174|Actinobacteria K Bacterial regulatory proteins, tetR family icaR - - - - - - - - - - - TetR_N GGPLMPOG_00509 547043.BIFPSEUDO_02894 2.75e-249 690.0 COG0552@1|root,COG0552@2|Bacteria,2GJQH@201174|Actinobacteria,4CZZX@85004|Bifidobacteriales 201174|Actinobacteria U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) ftsY GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - SRP54,SRP54_N GGPLMPOG_00510 547043.BIFPSEUDO_02893 1.45e-302 828.0 COG0004@1|root,COG0004@2|Bacteria,2GIZK@201174|Actinobacteria,4CZA0@85004|Bifidobacteriales 201174|Actinobacteria U Ammonium Transporter Family amt - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp GGPLMPOG_00511 158787.BSCA_0063 2.56e-72 217.0 COG0347@1|root,COG0347@2|Bacteria,2IKN1@201174|Actinobacteria,4D0VD@85004|Bifidobacteriales 201174|Actinobacteria K Nitrogen regulatory protein P-II glnB GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0008150,GO:0016020,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043531,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K04751 ko02020,map02020 - - - ko00000,ko00001 - - - P-II GGPLMPOG_00512 547043.BIFPSEUDO_02891 0.0 1192.0 COG2844@1|root,COG2844@2|Bacteria,2GMKT@201174|Actinobacteria,4D07P@85004|Bifidobacteriales 201174|Actinobacteria O Nucleotidyltransferase domain glnD GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008773,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0030312,GO:0044464,GO:0070566,GO:0070569,GO:0071944,GO:0140096 2.7.7.59 ko:K00990 ko02020,map02020 - - - ko00000,ko00001,ko01000 - - - ACT,GlnD_UR_UTase,HD,NTP_transf_2 GGPLMPOG_00513 547043.BIFPSEUDO_02890 0.0 889.0 COG0305@1|root,COG0305@2|Bacteria,2GKXQ@201174|Actinobacteria,4CYY3@85004|Bifidobacteriales 201174|Actinobacteria L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C GGPLMPOG_00514 566552.BIFCAT_00167 0.0 890.0 COG0771@1|root,COG0771@2|Bacteria,2GK18@201174|Actinobacteria,4CYTP@85004|Bifidobacteriales 201174|Actinobacteria M Domain of unknown function (DUF1727) murE - - - - - - - - - - - DUF1727,Mur_ligase_M GGPLMPOG_00515 547043.BIFPSEUDO_02888 4.63e-175 488.0 COG3442@1|root,COG3442@2|Bacteria,2GKPV@201174|Actinobacteria,4CZJ1@85004|Bifidobacteriales 201174|Actinobacteria S CobB/CobQ-like glutamine amidotransferase domain cobQ2 - - ko:K07009 - - - - ko00000 - - - GATase_3 GGPLMPOG_00516 547043.BIFPSEUDO_02886 4.06e-42 139.0 COG3937@1|root,COG3937@2|Bacteria,2GS3M@201174|Actinobacteria,4D1FE@85004|Bifidobacteriales 201174|Actinobacteria S granule-associated protein - - - - - - - - - - - - Phasin GGPLMPOG_00517 547043.BIFPSEUDO_02885 0.0 1113.0 COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,4CZ45@85004|Bifidobacteriales 201174|Actinobacteria S ABC1 family - - - ko:K03688 - - - - ko00000 - - - ABC1 GGPLMPOG_00518 547043.BIFPSEUDO_02884 1.31e-245 674.0 COG1609@1|root,COG1609@2|Bacteria,2GJV7@201174|Actinobacteria,4CZND@85004|Bifidobacteriales 201174|Actinobacteria K Periplasmic binding protein domain - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 GGPLMPOG_00519 547043.BIFPSEUDO_02883 5.38e-316 862.0 COG1653@1|root,COG1653@2|Bacteria,2GNYN@201174|Actinobacteria,4D08X@85004|Bifidobacteriales 201174|Actinobacteria G Bacterial extracellular solute-binding protein - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_8 GGPLMPOG_00521 547043.BIFPSEUDO_02882 5.95e-214 593.0 COG1175@1|root,COG1175@2|Bacteria,2GMJG@201174|Actinobacteria,4D0BR@85004|Bifidobacteriales 201174|Actinobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02025,ko:K10189 ko02010,map02010 M00199,M00207 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.4 - - BPD_transp_1 GGPLMPOG_00522 547043.BIFPSEUDO_02880 3.39e-187 521.0 COG0395@1|root,COG0395@2|Bacteria,2GJNN@201174|Actinobacteria,4D039@85004|Bifidobacteriales 201174|Actinobacteria G Binding-protein-dependent transport system inner membrane component - - - ko:K02026 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 GGPLMPOG_00523 547043.BIFPSEUDO_02879 0.0 1347.0 COG3533@1|root,COG3533@2|Bacteria,2GM60@201174|Actinobacteria,4CYSU@85004|Bifidobacteriales 201174|Actinobacteria S Beta-L-arabinofuranosidase, GH127 - - 3.2.1.185 ko:K09955,ko:K18205 - - - - ko00000,ko01000 - GH127 - Glyco_hydro_127 GGPLMPOG_00524 547043.BIFPSEUDO_02878 0.0 3605.0 COG1196@1|root,COG3408@1|root,COG1196@2|Bacteria,COG3408@2|Bacteria,2H8PD@201174|Actinobacteria,4D2YI@85004|Bifidobacteriales 201174|Actinobacteria DG Bacterial Ig-like domain (group 4) - - 3.2.1.187 ko:K18206 - - - - ko00000,ko01000 - GH121 - Big_3_2,Big_4,F5_F8_type_C,FIVAR GGPLMPOG_00525 547043.BIFPSEUDO_02877 0.0 2113.0 COG3507@1|root,COG3507@2|Bacteria,2I911@201174|Actinobacteria,4D2SA@85004|Bifidobacteriales 201174|Actinobacteria G Bacterial Ig-like domain (group 4) - - - - - - - - - - - - Big_4,Glyco_hydro_43 GGPLMPOG_00526 547043.BIFPSEUDO_02876 4.63e-263 721.0 COG0584@1|root,COG0584@2|Bacteria,2GNM5@201174|Actinobacteria,4CYS4@85004|Bifidobacteriales 201174|Actinobacteria C Glycerophosphoryl diester phosphodiesterase family glpQ - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD,Laminin_G_3 GGPLMPOG_00527 547043.BIFPSEUDO_02875 1.64e-151 426.0 COG0035@1|root,COG0035@2|Bacteria,2GPJE@201174|Actinobacteria,4CYVS@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate upp GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 ko:K00761 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000 - - - UPRTase GGPLMPOG_00528 547043.BIFPSEUDO_02874 8.12e-134 382.0 28MMU@1|root,2ZAXG@2|Bacteria,2HAD5@201174|Actinobacteria,4CZ1Q@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_00529 547043.BIFPSEUDO_02873 1.08e-287 785.0 COG0494@1|root,COG2062@1|root,COG0494@2|Bacteria,COG2062@2|Bacteria,2GNRV@201174|Actinobacteria,4CZ90@85004|Bifidobacteriales 201174|Actinobacteria LT Phosphoglycerate mutase family mutT - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - His_Phos_1,NUDIX GGPLMPOG_00530 547043.BIFPSEUDO_02872 0.0 1457.0 COG0855@1|root,COG0855@2|Bacteria,2GJ0B@201174|Actinobacteria,4CYXH@85004|Bifidobacteriales 201174|Actinobacteria P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) ppk - 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PP_kinase,PP_kinase_C,PP_kinase_N GGPLMPOG_00531 547043.BIFPSEUDO_02870 6.13e-182 507.0 COG0455@1|root,COG0455@2|Bacteria,2HZIH@201174|Actinobacteria,4D0JG@85004|Bifidobacteriales 201174|Actinobacteria D bacterial-type flagellum organization - - - - - - - - - - - - ParA GGPLMPOG_00532 547043.BIFPSEUDO_02869 5.94e-237 651.0 COG4962@1|root,COG4962@2|Bacteria,2GKKJ@201174|Actinobacteria,4CZF2@85004|Bifidobacteriales 201174|Actinobacteria U Type II IV secretion system protein cpaF - - ko:K02283 - - - - ko00000,ko02035,ko02044 - - - T2SSE GGPLMPOG_00533 547043.BIFPSEUDO_02868 2.39e-159 448.0 COG4965@1|root,COG4965@2|Bacteria,2GRXU@201174|Actinobacteria,4D1A3@85004|Bifidobacteriales 201174|Actinobacteria U Type ii secretion system - - - ko:K12510 - - - - ko00000,ko02044 - - - - GGPLMPOG_00534 547043.BIFPSEUDO_02867 3.29e-116 333.0 COG2064@1|root,COG2064@2|Bacteria,2I2FP@201174|Actinobacteria,4D16W@85004|Bifidobacteriales 201174|Actinobacteria NU Type II secretion system (T2SS), protein F - - - - - - - - - - - - T2SSF GGPLMPOG_00535 547043.BIFPSEUDO_02865 3.15e-56 175.0 2EHCF@1|root,33B4A@2|Bacteria,2GR72@201174|Actinobacteria,4D1FR@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF4244) - - - - - - - - - - - - DUF4244 GGPLMPOG_00536 547043.BIFPSEUDO_02864 5.15e-79 235.0 COG4961@1|root,COG4961@2|Bacteria,2GT3N@201174|Actinobacteria,4D1E4@85004|Bifidobacteriales 201174|Actinobacteria U TadE-like protein - - - - - - - - - - - - TadE GGPLMPOG_00537 566552.BIFCAT_01987 6.51e-71 215.0 2DRBM@1|root,33B4F@2|Bacteria,2HZRZ@201174|Actinobacteria,4D1G6@85004|Bifidobacteriales 201174|Actinobacteria S TIGRFAM helicase secretion neighborhood TadE-like protein - - - - - - - - - - - - Tad GGPLMPOG_00538 547043.BIFPSEUDO_02862 3.34e-271 742.0 COG1597@1|root,COG1597@2|Bacteria,2GK3P@201174|Actinobacteria,4CZ1S@85004|Bifidobacteriales 201174|Actinobacteria I Diacylglycerol kinase catalytic domain protein - - 2.7.1.107 ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 - R02240 RC00002,RC00017 ko00000,ko00001,ko01000 - - - DAGK_cat GGPLMPOG_00539 547043.BIFPSEUDO_02861 6.51e-249 681.0 28H6R@1|root,2Z7J3@2|Bacteria,2I9RC@201174|Actinobacteria,4CZ7J@85004|Bifidobacteriales 201174|Actinobacteria S Psort location CytoplasmicMembrane, score - - - - - - - - - - - - - GGPLMPOG_00540 547043.BIFPSEUDO_02860 1.57e-128 366.0 COG1309@1|root,COG1309@2|Bacteria,2GND5@201174|Actinobacteria,4CZUU@85004|Bifidobacteriales 201174|Actinobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N GGPLMPOG_00541 547043.BIFPSEUDO_02859 0.0 1464.0 COG2812@1|root,COG2812@2|Bacteria,2GJKA@201174|Actinobacteria,4CZMY@85004|Bifidobacteriales 201174|Actinobacteria L DNA polymerase III subunit gamma tau dnaX GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3 GGPLMPOG_00542 566552.BIFCAT_01982 6.41e-136 385.0 COG0353@1|root,COG0353@2|Bacteria,2GJY0@201174|Actinobacteria,4CZRI@85004|Bifidobacteriales 201174|Actinobacteria L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO recR - - ko:K06187 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - HHH,RecR,Toprim_4 GGPLMPOG_00543 547043.BIFPSEUDO_02856 7.1e-175 488.0 COG0527@1|root,COG0527@2|Bacteria,2GN0G@201174|Actinobacteria,4CYSD@85004|Bifidobacteriales 201174|Actinobacteria E Amino acid kinase family ask GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT,ACT_7 GGPLMPOG_00544 566552.BIFCAT_01979 1.17e-125 358.0 COG0527@1|root,COG0527@2|Bacteria,2GN0G@201174|Actinobacteria,4D00P@85004|Bifidobacteriales 201174|Actinobacteria E ACT domain ask GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT,ACT_7 GGPLMPOG_00545 547043.BIFPSEUDO_02854 5.73e-264 723.0 COG0136@1|root,COG0136@2|Bacteria,2GJJ8@201174|Actinobacteria,4CZPY@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd GO:0003674,GO:0003824,GO:0004073,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv3708c Semialdhyde_dh,Semialdhyde_dhC GGPLMPOG_00547 1321775.HMPREF1980_01321 1.11e-157 447.0 COG4725@1|root,COG4725@2|Bacteria,2IIR3@201174|Actinobacteria,4D53I@85005|Actinomycetales 201174|Actinobacteria KT MT-A70 - - - - - - - - - - - - MT-A70 GGPLMPOG_00548 1321775.HMPREF1980_01320 1.78e-106 315.0 28J7N@1|root,2Z931@2|Bacteria,2IBUF@201174|Actinobacteria,4D6S3@85005|Actinomycetales 201174|Actinobacteria L Restriction endonuclease BglII - - - - - - - - - - - - Endonuc-BglII GGPLMPOG_00549 78346.BRUM_0592 6.85e-75 241.0 28MKK@1|root,2ZAWR@2|Bacteria,2IS2W@201174|Actinobacteria,4D1DD@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - RNA_helicase,Viral_Rep GGPLMPOG_00550 570268.ANBB01000064_gene987 4.53e-24 108.0 COG1674@1|root,COG1674@2|Bacteria,2GJA3@201174|Actinobacteria,4EHXX@85012|Streptosporangiales 201174|Actinobacteria D FtsK/SpoIIIE family - - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_SpoIIIE GGPLMPOG_00553 1034943.BN1094_01506 0.00015 43.5 2B1SK@1|root,31U8D@2|Bacteria,1NPBQ@1224|Proteobacteria,1TAE1@1236|Gammaproteobacteria,1JEVQ@118969|Legionellales 118969|Legionellales - - - - - - - - - - - - - - - GGPLMPOG_00555 1688.BCUN_0907 3e-17 86.3 COG4974@1|root,COG4974@2|Bacteria,2HD2H@201174|Actinobacteria,4D2VK@85004|Bifidobacteriales 201174|Actinobacteria L Phage integrase family - - - - - - - - - - - - Phage_int_SAM_3,Phage_integrase GGPLMPOG_00556 762211.BSTEL_0201 5.96e-58 197.0 COG4974@1|root,COG4974@2|Bacteria,2HD2H@201174|Actinobacteria,4D2VK@85004|Bifidobacteriales 201174|Actinobacteria L Phage integrase family - - - - - - - - - - - - Phage_int_SAM_3,Phage_integrase GGPLMPOG_00557 547043.BIFPSEUDO_02853 9.43e-147 416.0 2C7PT@1|root,2ZXN2@2|Bacteria,2GM64@201174|Actinobacteria,4CYPY@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_00558 547043.BIFPSEUDO_02852 0.0 1038.0 COG1409@1|root,COG1409@2|Bacteria,2GNKK@201174|Actinobacteria,4CZMC@85004|Bifidobacteriales 201174|Actinobacteria S Calcineurin-like phosphoesterase - - - - - - - - - - - - Metallophos GGPLMPOG_00559 547043.BIFPSEUDO_02851 0.0 1263.0 COG0119@1|root,COG0119@2|Bacteria,2GISX@201174|Actinobacteria,4CZYW@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) leuA GO:0000287,GO:0003674,GO:0003824,GO:0003852,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0019752,GO:0030145,GO:0030955,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0046912,GO:0046914,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - - HMGL-like,LeuA_dimer GGPLMPOG_00560 547043.BIFPSEUDO_02850 0.0 1162.0 COG3507@1|root,COG3507@2|Bacteria,2IECJ@201174|Actinobacteria,4D07X@85004|Bifidobacteriales 201174|Actinobacteria G C-terminal of Glycosyl hydrolases family 43 - - 3.2.1.99 ko:K06113 - - - - ko00000,ko01000 - GH43 - GH43_C,Glyco_hydro_43 GGPLMPOG_00561 547043.BIFPSEUDO_02848 0.0 1078.0 COG3507@1|root,COG3507@2|Bacteria,2IECJ@201174|Actinobacteria,4CZF0@85004|Bifidobacteriales 201174|Actinobacteria G C-terminal of Glycosyl hydrolases family 43 - - 3.2.1.99 ko:K06113 - - - - ko00000,ko01000 - GH43 - GH43_C,Glyco_hydro_43 GGPLMPOG_00562 547043.BIFPSEUDO_02849 0.0 1433.0 COG3940@1|root,COG3940@2|Bacteria,2GJJP@201174|Actinobacteria,4CZFV@85004|Bifidobacteriales 201174|Actinobacteria G Glycosyl hydrolases family 43 - - - - - - - - - - - - Big_4,FIVAR,Glyco_hydro_43,Laminin_G_3 GGPLMPOG_00563 547043.BIFPSEUDO_02847 1.54e-249 686.0 COG1609@1|root,COG1609@2|Bacteria,2GJ5Q@201174|Actinobacteria,4D040@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn _helix lactose operon repressor - - - - - - - - - - - - LacI,Peripla_BP_3 GGPLMPOG_00564 547043.BIFPSEUDO_02845 8.04e-260 710.0 COG3940@1|root,COG3940@2|Bacteria,2GJJP@201174|Actinobacteria,4CZVP@85004|Bifidobacteriales 201174|Actinobacteria G Glycosyl hydrolases family 43 - - - - - - - - - - - - AbfB,Glyco_hydro_43 GGPLMPOG_00565 547043.BIFPSEUDO_02843 0.0 878.0 COG1653@1|root,COG1653@2|Bacteria,2GZ1E@201174|Actinobacteria,4CZNE@85004|Bifidobacteriales 201174|Actinobacteria G Bacterial extracellular solute-binding protein - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_1,SBP_bac_8 GGPLMPOG_00566 547043.BIFPSEUDO_02842 7.58e-217 599.0 COG1175@1|root,COG1175@2|Bacteria,2GKJI@201174|Actinobacteria,4D2TA@85004|Bifidobacteriales 201174|Actinobacteria G Binding-protein-dependent transport system inner membrane component - - - ko:K02025 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 GGPLMPOG_00567 547043.BIFPSEUDO_02841 3.71e-206 571.0 COG0395@1|root,COG0395@2|Bacteria,2GMTH@201174|Actinobacteria,4CZQ9@85004|Bifidobacteriales 201174|Actinobacteria U Binding-protein-dependent transport system inner membrane component - - - ko:K02026 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 GGPLMPOG_00568 547043.BIFPSEUDO_02839 0.0 1719.0 COG3533@1|root,COG3533@2|Bacteria,2GM60@201174|Actinobacteria,4D08B@85004|Bifidobacteriales 201174|Actinobacteria S Beta-L-arabinofuranosidase, GH127 - - - ko:K09955 - - - - ko00000 - - - Cadherin-like,DUF4986,Glyco_hydro_127,Laminin_G_3 GGPLMPOG_00569 566552.BIFCAT_01971 0.0 1346.0 COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria,4CZQZ@85004|Bifidobacteriales 201174|Actinobacteria M Transglycosylase pbp5 - - - - - - - - - - - Transgly,Transpeptidase GGPLMPOG_00570 547043.BIFPSEUDO_02836 1.1e-276 756.0 COG1260@1|root,COG1260@2|Bacteria,2GKHB@201174|Actinobacteria,4D02Z@85004|Bifidobacteriales 201174|Actinobacteria I Myo-inositol-1-phosphate synthase ino1 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 ko:K01858 ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130 - R07324 RC01804 ko00000,ko00001,ko01000 - - - Inos-1-P_synth GGPLMPOG_00571 547043.BIFPSEUDO_02834 2.2e-298 812.0 COG0562@1|root,COG0562@2|Bacteria,2GK2Z@201174|Actinobacteria,4CZ2W@85004|Bifidobacteriales 201174|Actinobacteria M UDP-galactopyranose mutase glf GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008767,GO:0009273,GO:0009987,GO:0016020,GO:0016853,GO:0016866,GO:0030312,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071766,GO:0071840,GO:0071944 5.4.99.9 ko:K01854 ko00052,ko00520,map00052,map00520 - R00505,R09009 RC00317,RC02396 ko00000,ko00001,ko01000 - - iNJ661.Rv3809c GLF,NAD_binding_8 GGPLMPOG_00572 547043.BIFPSEUDO_02833 8.84e-245 674.0 COG0671@1|root,COG0671@2|Bacteria,2HIXE@201174|Actinobacteria,4CYS6@85004|Bifidobacteriales 201174|Actinobacteria I PAP2 superfamily - - - - - - - - - - - - PAP2 GGPLMPOG_00573 547043.BIFPSEUDO_02832 0.0 1885.0 COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,2GJU7@201174|Actinobacteria,4CZ85@85004|Bifidobacteriales 201174|Actinobacteria L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010605,GO:0016020,GO:0016853,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0040007,GO:0043086,GO:0043167,GO:0043169,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060700,GO:0060701,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0140097 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topoisom_bac,Toprim,Toprim_C_rpt GGPLMPOG_00574 547043.BIFPSEUDO_02831 2.11e-145 410.0 COG0125@1|root,COG0125@2|Bacteria,2GNTI@201174|Actinobacteria,4CYQ8@85004|Bifidobacteriales 201174|Actinobacteria F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis tmk - 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 - - - MFS_1,MFS_3,Thymidylate_kin GGPLMPOG_00575 566552.BIFCAT_01732 2.1e-251 692.0 COG0470@1|root,COG0470@2|Bacteria,2GJ8C@201174|Actinobacteria,4CZ4Y@85004|Bifidobacteriales 201174|Actinobacteria L DNA polymerase III holB GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNApol3-delta_C GGPLMPOG_00576 547043.BIFPSEUDO_02829 2.51e-237 654.0 COG1609@1|root,COG1609@2|Bacteria,2GJRG@201174|Actinobacteria,4CZ05@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn _helix lactose operon repressor - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 GGPLMPOG_00577 547043.BIFPSEUDO_02827 6.22e-52 164.0 COG1925@1|root,COG1925@2|Bacteria,2GQX6@201174|Actinobacteria,4D19B@85004|Bifidobacteriales 201174|Actinobacteria G PTS HPr component phosphorylation site hpr - - ko:K11189 - - - - ko00000,ko02000 4.A.2.1 - - PTS-HPr GGPLMPOG_00578 547043.BIFPSEUDO_02825 0.0 1031.0 COG1080@1|root,COG1080@2|Bacteria,2GIZZ@201174|Actinobacteria,4CZ52@85004|Bifidobacteriales 201174|Actinobacteria G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) ptsI - 2.7.3.9 ko:K08483 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 8.A.7 - - PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C GGPLMPOG_00579 547043.BIFPSEUDO_02824 5.02e-139 392.0 COG1881@1|root,COG1881@2|Bacteria,2I5K1@201174|Actinobacteria,4CZSW@85004|Bifidobacteriales 201174|Actinobacteria S Phosphatidylethanolamine-binding protein - - - ko:K06910 - - - - ko00000 - - - PBP GGPLMPOG_00580 547043.BIFPSEUDO_02823 0.0 1080.0 COG4690@1|root,COG4690@2|Bacteria,2GM80@201174|Actinobacteria,4CZI5@85004|Bifidobacteriales 201174|Actinobacteria E Peptidase family C69 pepD - - ko:K08659 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C69 GGPLMPOG_00581 547043.BIFPSEUDO_02822 0.0 992.0 COG2759@1|root,COG2759@2|Bacteria,2GT0X@201174|Actinobacteria,4CZ7P@85004|Bifidobacteriales 201174|Actinobacteria F Formate-tetrahydrofolate ligase fhs - 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 - - - FTHFS GGPLMPOG_00582 547043.BIFPSEUDO_02821 1.58e-81 241.0 COG1942@1|root,COG1942@2|Bacteria,2II0W@201174|Actinobacteria,4D0VC@85004|Bifidobacteriales 201174|Actinobacteria S Macrophage migration inhibitory factor (MIF) - - - - - - - - - - - - MIF GGPLMPOG_00583 547043.BIFPSEUDO_02820 1.06e-123 352.0 COG2246@1|root,COG2246@2|Bacteria,2HZBR@201174|Actinobacteria,4CZM6@85004|Bifidobacteriales 201174|Actinobacteria S GtrA-like protein - - - - - - - - - - - - GtrA GGPLMPOG_00584 547043.BIFPSEUDO_02819 0.0 916.0 COG0477@1|root,COG2814@2|Bacteria,2GKMQ@201174|Actinobacteria,4CZ6D@85004|Bifidobacteriales 201174|Actinobacteria EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 GGPLMPOG_00585 547043.BIFPSEUDO_02818 1.24e-158 444.0 COG0406@1|root,COG0406@2|Bacteria,2GMXF@201174|Actinobacteria,4CZ0Z@85004|Bifidobacteriales 201174|Actinobacteria G Phosphoglycerate mutase family - GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - - - - - - - - - - His_Phos_1 GGPLMPOG_00586 547043.BIFPSEUDO_02816 1.86e-242 666.0 2BR5C@1|root,32K3E@2|Bacteria,2I8T9@201174|Actinobacteria,4CZ8U@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_00587 547043.BIFPSEUDO_02815 2.78e-162 473.0 COG3152@1|root,COG3152@2|Bacteria,2IQHK@201174|Actinobacteria,4D0Q2@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF805) - - - - - - - - - - - - DUF805 GGPLMPOG_00588 547043.BIFPSEUDO_02813 0.0 1017.0 COG0008@1|root,COG0008@2|Bacteria,2GJJS@201174|Actinobacteria,4CZHK@85004|Bifidobacteriales 201174|Actinobacteria J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - iNJ661.Rv2992c tRNA-synt_1c GGPLMPOG_00591 547043.BIFPSEUDO_02810 0.0 954.0 COG1409@1|root,COG1409@2|Bacteria,2HRDZ@201174|Actinobacteria,4CYQR@85004|Bifidobacteriales 201174|Actinobacteria S Calcineurin-like phosphoesterase - - - - - - - - - - - - Metallophos GGPLMPOG_00592 547043.BIFPSEUDO_02809 1.9e-180 503.0 COG1414@1|root,COG1414@2|Bacteria,2GKB0@201174|Actinobacteria,4CZ9D@85004|Bifidobacteriales 201174|Actinobacteria K Transcriptional regulator, IclR family, C-terminal domain protein ltbR - - - - - - - - - - - HTH_IclR,IclR GGPLMPOG_00593 547043.BIFPSEUDO_02807 0.0 937.0 COG0065@1|root,COG0065@2|Bacteria,2GKT7@201174|Actinobacteria,4CYUC@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuC - 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase GGPLMPOG_00594 547043.BIFPSEUDO_02806 2.1e-169 473.0 COG0066@1|root,COG0066@2|Bacteria,2GJ8Z@201174|Actinobacteria,4CZ2F@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuD - 4.2.1.33,4.2.1.35 ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R10170 RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase_C GGPLMPOG_00595 547043.BIFPSEUDO_02804 6.6e-259 712.0 COG0167@1|root,COG0167@2|Bacteria,2GJMN@201174|Actinobacteria,4CZKM@85004|Bifidobacteriales 201174|Actinobacteria F Dihydroorotate dehydrogenase pyr - 1.3.98.1 ko:K00226 ko00240,ko01100,map00240,map01100 M00051 R01867 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh GGPLMPOG_00596 547043.BIFPSEUDO_02803 0.0 885.0 COG0766@1|root,COG0766@2|Bacteria,2GJPW@201174|Actinobacteria,4CZN7@85004|Bifidobacteriales 201174|Actinobacteria M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA - 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - - EPSP_synthase GGPLMPOG_00597 547043.BIFPSEUDO_02801 1.73e-225 620.0 COG0204@1|root,COG0204@2|Bacteria,2GKVA@201174|Actinobacteria,4CZG0@85004|Bifidobacteriales 201174|Actinobacteria I Phosphate acyltransferases plsC2 - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase GGPLMPOG_00598 547043.BIFPSEUDO_02800 1.31e-228 631.0 COG0240@1|root,COG0240@2|Bacteria,2GJSD@201174|Actinobacteria,4CZHP@85004|Bifidobacteriales 201174|Actinobacteria I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus gpsA - 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N GGPLMPOG_00599 547043.BIFPSEUDO_02799 2.7e-279 763.0 COG1181@1|root,COG1181@2|Bacteria,2GITC@201174|Actinobacteria,4CZ1R@85004|Bifidobacteriales 201174|Actinobacteria F Belongs to the D-alanine--D-alanine ligase family ddl GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008716,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N GGPLMPOG_00600 547043.BIFPSEUDO_02798 3.99e-278 760.0 COG1840@1|root,COG1840@2|Bacteria,2GJFH@201174|Actinobacteria,4CZHC@85004|Bifidobacteriales 201174|Actinobacteria P Bacterial extracellular solute-binding protein - - - ko:K02055 ko02024,map02024 M00193 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11 - - SBP_bac_6 GGPLMPOG_00601 547043.BIFPSEUDO_02797 1.95e-204 568.0 COG4132@1|root,COG4132@2|Bacteria,2GNDF@201174|Actinobacteria,4CZHE@85004|Bifidobacteriales 201174|Actinobacteria U Binding-protein-dependent transport system inner membrane component - - - ko:K02054 ko02024,map02024 M00193 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11 - - BPD_transp_1 GGPLMPOG_00602 547043.BIFPSEUDO_02796 2.76e-189 527.0 COG1177@1|root,COG1177@2|Bacteria,2GM0E@201174|Actinobacteria,4CZ2N@85004|Bifidobacteriales 201174|Actinobacteria U Binding-protein-dependent transport system inner membrane component - - - ko:K02053 ko02024,map02024 M00193 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11 - - BPD_transp_1 GGPLMPOG_00603 547043.BIFPSEUDO_02795 1.95e-272 746.0 COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4CZPE@85004|Bifidobacteriales 201174|Actinobacteria E Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system - - - ko:K02052 ko02024,map02024 M00193 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11 - - ABC_tran,TOBE_2 GGPLMPOG_00604 547043.BIFPSEUDO_02794 5.42e-221 615.0 COG1266@1|root,COG1266@2|Bacteria,2I3DW@201174|Actinobacteria,4CZJZ@85004|Bifidobacteriales 201174|Actinobacteria S CAAX protease self-immunity - - - - - - - - - - - - Abi GGPLMPOG_00605 547043.BIFPSEUDO_02793 1.38e-177 496.0 COG0668@1|root,COG0668@2|Bacteria,2GZI1@201174|Actinobacteria,4CZ0A@85004|Bifidobacteriales 201174|Actinobacteria M Mechanosensitive ion channel - - - - - - - - - - - - MS_channel,cNMP_binding GGPLMPOG_00606 547043.BIFPSEUDO_02792 5.84e-293 800.0 COG1073@1|root,COG1073@2|Bacteria,2GMT6@201174|Actinobacteria,4CZ4Q@85004|Bifidobacteriales 201174|Actinobacteria S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - DUF2974 GGPLMPOG_00607 547043.BIFPSEUDO_02791 2.18e-289 790.0 COG1073@1|root,COG1073@2|Bacteria,2GMT6@201174|Actinobacteria,4CZ4Q@85004|Bifidobacteriales 201174|Actinobacteria S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - DUF2974 GGPLMPOG_00608 547043.BIFPSEUDO_02790 2.71e-160 449.0 COG1309@1|root,COG1309@2|Bacteria,2I8SX@201174|Actinobacteria,4CZXQ@85004|Bifidobacteriales 201174|Actinobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N GGPLMPOG_00609 547043.BIFPSEUDO_02789 6.54e-293 798.0 COG0436@1|root,COG0436@2|Bacteria,2GPM3@201174|Actinobacteria,4CZ6T@85004|Bifidobacteriales 201174|Actinobacteria E Psort location Cytoplasmic, score 8.87 - - 2.6.1.1 ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 GGPLMPOG_00610 1680.BADO_0207 2.27e-107 311.0 COG3265@1|root,COG3265@2|Bacteria,2GMW2@201174|Actinobacteria,4D0QX@85004|Bifidobacteriales 201174|Actinobacteria F Shikimate kinase gntK - 2.7.1.12 ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 - R01737 RC00002,RC00017 ko00000,ko00001,ko01000 - - - AAA_33,SKI GGPLMPOG_00611 547043.BIFPSEUDO_02783 1.29e-152 431.0 COG2186@1|root,COG2186@2|Bacteria,2GKBM@201174|Actinobacteria,4CYZS@85004|Bifidobacteriales 201174|Actinobacteria K FCD gntR - - - - - - - - - - - FCD,GntR GGPLMPOG_00612 547043.BIFPSEUDO_02781 1.42e-305 836.0 COG2270@1|root,COG2270@2|Bacteria,2GJCW@201174|Actinobacteria,4CZU3@85004|Bifidobacteriales 201174|Actinobacteria S Vacuole effluxer Atg22 like - - - ko:K06902 ko04138,map04138 - - - ko00000,ko00001,ko02000,ko04131 2.A.1.24,9.A.15.1 - - ATG22 GGPLMPOG_00613 547043.BIFPSEUDO_02780 0.0 1323.0 COG0457@1|root,COG0457@2|Bacteria,2I8FI@201174|Actinobacteria,4CZDI@85004|Bifidobacteriales 201174|Actinobacteria S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - TPR_8 GGPLMPOG_00614 1680.BADO_0211 1.82e-41 135.0 COG0227@1|root,COG0227@2|Bacteria,2GQNU@201174|Actinobacteria,4D17Q@85004|Bifidobacteriales 201174|Actinobacteria J Ribosomal L28 family rpmB GO:0003674,GO:0003735,GO:0005198 - ko:K02902 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L28 GGPLMPOG_00615 547043.BIFPSEUDO_02778 0.0 1712.0 COG1200@1|root,COG1200@2|Bacteria,2GKA3@201174|Actinobacteria,4CYTV@85004|Bifidobacteriales 201174|Actinobacteria L helicase superfamily c-terminal domain recG GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge,tRNA_anti-codon GGPLMPOG_00616 547043.BIFPSEUDO_02777 6.19e-136 385.0 COG0742@1|root,COG0742@2|Bacteria,2GQ3G@201174|Actinobacteria,4D0GU@85004|Bifidobacteriales 201174|Actinobacteria L Conserved hypothetical protein 95 rsmD - 2.1.1.171 ko:K08316 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Cons_hypoth95 GGPLMPOG_00617 547043.BIFPSEUDO_02776 6.3e-193 540.0 COG0336@1|root,COG0336@2|Bacteria,2GJ1G@201174|Actinobacteria,4CZ7A@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the RNA methyltransferase TrmD family trmD GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 ko:K00554 - - R00597 RC00003,RC00334 ko00000,ko01000,ko03016 - - - Acetyltransf_1,tRNA_m1G_MT GGPLMPOG_00618 547043.BIFPSEUDO_02775 8.88e-138 389.0 COG0806@1|root,COG0806@2|Bacteria,2GK4I@201174|Actinobacteria,4D0C6@85004|Bifidobacteriales 201174|Actinobacteria J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes rimM GO:0008150,GO:0040007 - ko:K02860 - - - - ko00000,ko03009 - - - PRC,RimM GGPLMPOG_00619 1435051.BMOU_1596 5.05e-47 150.0 COG1837@1|root,COG1837@2|Bacteria,2IQ4C@201174|Actinobacteria,4D16Z@85004|Bifidobacteriales 201174|Actinobacteria S Belongs to the UPF0109 family - GO:0008150,GO:0040007 - ko:K06960 - - - - ko00000 - - - KH_4 GGPLMPOG_00620 547043.BIFPSEUDO_02773 1.08e-80 242.0 COG0228@1|root,COG0228@2|Bacteria,2IKU0@201174|Actinobacteria,4D0PE@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the bacterial ribosomal protein bS16 family rpsP GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02959 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S16 GGPLMPOG_00621 547043.BIFPSEUDO_02771 3.53e-232 640.0 COG3021@1|root,COG3021@2|Bacteria,2GK2H@201174|Actinobacteria,4CYS3@85004|Bifidobacteriales 201174|Actinobacteria S Endonuclease/Exonuclease/phosphatase family - - - - - - - - - - - - Exo_endo_phos GGPLMPOG_00622 547043.BIFPSEUDO_02770 0.0 1012.0 COG0541@1|root,COG0541@2|Bacteria,2GK4R@201174|Actinobacteria,4CYY1@85004|Bifidobacteriales 201174|Actinobacteria U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY ffh GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB GGPLMPOG_00623 547043.BIFPSEUDO_02769 0.0 1066.0 COG0215@1|root,COG0215@2|Bacteria,2GJF2@201174|Actinobacteria,4CZZ9@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the class-I aminoacyl-tRNA synthetase family cysS GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,tRNA-synt_1e GGPLMPOG_00624 547043.BIFPSEUDO_02768 3.99e-194 538.0 COG0518@1|root,COG0518@2|Bacteria,2GNA6@201174|Actinobacteria,4CYR4@85004|Bifidobacteriales 201174|Actinobacteria F Peptidase C26 - - 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase,Methyltransf_11 GGPLMPOG_00625 547043.BIFPSEUDO_02767 0.0 1307.0 COG0488@1|root,COG0488@2|Bacteria,2GJ5M@201174|Actinobacteria,4CZCU@85004|Bifidobacteriales 201174|Actinobacteria S ABC transporter yjjK - - ko:K15738 - - - - ko00000,ko02000 3.A.1.120.6 - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn GGPLMPOG_00626 547043.BIFPSEUDO_02766 8.37e-126 358.0 2AR06@1|root,31G8Z@2|Bacteria,2IF1Q@201174|Actinobacteria,4D090@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_00627 547043.BIFPSEUDO_02765 1.54e-118 340.0 COG0440@1|root,COG0440@2|Bacteria,2GJCH@201174|Actinobacteria,4CYXX@85004|Bifidobacteriales 201174|Actinobacteria E ACT domain ilvN GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0030312,GO:0032991,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 ko:K01653 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - ACT,ACT_5,ALS_ss_C GGPLMPOG_00628 547043.BIFPSEUDO_02764 0.0 1271.0 COG0028@1|root,COG0028@2|Bacteria,2GKU4@201174|Actinobacteria,4CYR0@85004|Bifidobacteriales 201174|Actinobacteria H Thiamine pyrophosphate enzyme, central domain ilvB - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N GGPLMPOG_00629 547043.BIFPSEUDO_02762 8.48e-178 497.0 COG0571@1|root,COG0571@2|Bacteria,2GKER@201174|Actinobacteria,4CZ98@85004|Bifidobacteriales 201174|Actinobacteria J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm GGPLMPOG_00630 547043.BIFPSEUDO_02761 8.1e-36 121.0 COG0333@1|root,COG0333@2|Bacteria,2GQP3@201174|Actinobacteria,4D18N@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the bacterial ribosomal protein bL32 family rpmF - - ko:K02911 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_L32p GGPLMPOG_00631 547043.BIFPSEUDO_02760 1.75e-142 402.0 COG1399@1|root,COG1399@2|Bacteria,2GJTS@201174|Actinobacteria,4CZ0J@85004|Bifidobacteriales 201174|Actinobacteria S Uncharacterized ACR, COG1399 - GO:0008150,GO:0040007 - ko:K07040 - - - - ko00000 - - - DUF177 GGPLMPOG_00632 547043.BIFPSEUDO_02759 5.15e-172 481.0 2EKTZ@1|root,33EHP@2|Bacteria,2HZD3@201174|Actinobacteria,4CZV9@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_00633 547043.BIFPSEUDO_02758 6.03e-114 327.0 COG0669@1|root,COG0669@2|Bacteria,2GN1S@201174|Actinobacteria,4CYR5@85004|Bifidobacteriales 201174|Actinobacteria H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate coaD GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016043,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0022607,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034214,GO:0034641,GO:0034654,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0055086,GO:0065003,GO:0070566,GO:0071704,GO:0071840,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like GGPLMPOG_00634 547043.BIFPSEUDO_02757 4.15e-76 226.0 2CAFG@1|root,32ZDZ@2|Bacteria,2I800@201174|Actinobacteria,4D107@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF3039) - - - - - - - - - - - - DUF3039 GGPLMPOG_00635 547043.BIFPSEUDO_02756 6.86e-249 683.0 COG0667@1|root,COG0667@2|Bacteria,2GMT5@201174|Actinobacteria,4CZ25@85004|Bifidobacteriales 201174|Actinobacteria C Aldo/keto reductase family - - - ko:K19265 - - - - ko00000,ko01000 - - - Aldo_ket_red GGPLMPOG_00636 547043.BIFPSEUDO_02755 6.07e-102 295.0 COG0789@1|root,COG0789@2|Bacteria,2HZMI@201174|Actinobacteria,4D0Y1@85004|Bifidobacteriales 201174|Actinobacteria K MerR, DNA binding - - - - - - - - - - - - MerR_1 GGPLMPOG_00637 547043.BIFPSEUDO_02752 2.49e-156 439.0 COG0127@1|root,COG0127@2|Bacteria,2GM2B@201174|Actinobacteria,4CZ3F@85004|Bifidobacteriales 201174|Actinobacteria F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions rdgB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - - Ham1p_like GGPLMPOG_00638 547043.BIFPSEUDO_02751 2.31e-180 502.0 COG0689@1|root,COG0689@2|Bacteria,2GJFI@201174|Actinobacteria,4CZBF@85004|Bifidobacteriales 201174|Actinobacteria J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates rph GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 ko:K00989 - - - - ko00000,ko01000,ko03016 - - - RNase_PH,RNase_PH_C GGPLMPOG_00639 547043.BIFPSEUDO_02749 0.0 868.0 COG1488@1|root,COG1488@2|Bacteria,2GJAT@201174|Actinobacteria,4CYUR@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP pncB - 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 - R01724 RC00033 ko00000,ko00001,ko01000 - - - NAPRTase GGPLMPOG_00640 547043.BIFPSEUDO_02748 1.17e-306 835.0 COG2348@1|root,COG2348@2|Bacteria,2HZ91@201174|Actinobacteria,4CYZJ@85004|Bifidobacteriales 201174|Actinobacteria V Psort location Cytoplasmic, score 8.87 - - - ko:K12554 ko00550,ko01100,map00550,map01100 - R08780 RC00055,RC00064 ko00000,ko00001,ko01000,ko01011 - - - FemAB GGPLMPOG_00641 547043.BIFPSEUDO_02747 1.15e-298 816.0 COG2348@1|root,COG2348@2|Bacteria,2HZ91@201174|Actinobacteria,4CYZJ@85004|Bifidobacteriales 201174|Actinobacteria V Psort location Cytoplasmic, score 8.87 - - - ko:K12554 ko00550,ko01100,map00550,map01100 - R08780 RC00055,RC00064 ko00000,ko00001,ko01000,ko01011 - - - FemAB GGPLMPOG_00644 547043.BIFPSEUDO_02743 7.15e-232 639.0 COG0679@1|root,COG0679@2|Bacteria,2GN0R@201174|Actinobacteria,4CZ6C@85004|Bifidobacteriales 201174|Actinobacteria S Auxin Efflux Carrier - - - ko:K07088 - - - - ko00000 - - - Mem_trans GGPLMPOG_00645 566552.BIFCAT_01651 0.0 1138.0 COG0166@1|root,COG0166@2|Bacteria,2GJG0@201174|Actinobacteria,4CYVV@85004|Bifidobacteriales 201174|Actinobacteria G Belongs to the GPI family pgi - 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI GGPLMPOG_00646 547043.BIFPSEUDO_02738 3.37e-79 235.0 COG0335@1|root,COG0335@2|Bacteria,2IHRT@201174|Actinobacteria,4D0V2@85004|Bifidobacteriales 201174|Actinobacteria J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site rplS GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - ko:K02884 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L19 GGPLMPOG_00647 547043.BIFPSEUDO_02737 4.02e-158 442.0 COG0681@1|root,COG0681@2|Bacteria,2GIYN@201174|Actinobacteria,4CZEY@85004|Bifidobacteriales 201174|Actinobacteria U Belongs to the peptidase S26 family lepB - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 GGPLMPOG_00648 547043.BIFPSEUDO_02736 6.35e-176 490.0 COG0164@1|root,COG0164@2|Bacteria,2GJFN@201174|Actinobacteria,4CZ1U@85004|Bifidobacteriales 201174|Actinobacteria L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII GGPLMPOG_00649 547043.BIFPSEUDO_02735 6.56e-165 462.0 COG1136@1|root,COG1136@2|Bacteria,2GM25@201174|Actinobacteria,4D0FV@85004|Bifidobacteriales 201174|Actinobacteria V ATPases associated with a variety of cellular activities lolD - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran GGPLMPOG_00650 547043.BIFPSEUDO_02734 0.0 942.0 COG0577@1|root,COG0577@2|Bacteria,2GKF3@201174|Actinobacteria,4D03X@85004|Bifidobacteriales 201174|Actinobacteria V Efflux ABC transporter, permease protein - - - - - - - - - - - - FtsX GGPLMPOG_00651 566552.BIFCAT_01644 3.73e-212 588.0 COG0679@1|root,COG0679@2|Bacteria,2GNIA@201174|Actinobacteria,4CZFX@85004|Bifidobacteriales 201174|Actinobacteria S Transporter, auxin efflux carrier (AEC) family protein - - - ko:K07088 - - - - ko00000 - - - Mem_trans GGPLMPOG_00652 547043.BIFPSEUDO_02732 3.52e-295 805.0 COG0624@1|root,COG0624@2|Bacteria,2GK09@201174|Actinobacteria,4CZ9K@85004|Bifidobacteriales 201174|Actinobacteria E Peptidase dimerisation domain dapE - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 GGPLMPOG_00653 78346.BRUM_0637 0.0 1169.0 COG1530@1|root,COG1530@2|Bacteria,2GMM5@201174|Actinobacteria,4CYQT@85004|Bifidobacteriales 201174|Actinobacteria J Ribonuclease E/G family rne - 3.1.26.12 ko:K08300,ko:K08301 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 - - - IF2_N,RNase_E_G,S1 GGPLMPOG_00654 547043.BIFPSEUDO_02728 9.75e-61 187.0 COG0261@1|root,COG0261@2|Bacteria,2IQ9A@201174|Actinobacteria,4D10B@85004|Bifidobacteriales 201174|Actinobacteria J This protein binds to 23S rRNA in the presence of protein L20 rplU GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - ko:K02888 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L21p GGPLMPOG_00655 1435051.BMOU_1628 3.53e-52 164.0 COG0211@1|root,COG0211@2|Bacteria,2IQDI@201174|Actinobacteria,4D19N@85004|Bifidobacteriales 201174|Actinobacteria J Ribosomal L27 protein rpmA GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - ko:K02899 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27 GGPLMPOG_00656 547043.BIFPSEUDO_02726 0.0 1088.0 COG0536@1|root,COG0536@2|Bacteria,2GISB@201174|Actinobacteria,4CYWD@85004|Bifidobacteriales 201174|Actinobacteria S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg GO:0000287,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0032991,GO:0036211,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0046872,GO:0071704,GO:0071944,GO:1901564,GO:1990904 - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - DUF1967,GTP1_OBG,MMR_HSR1 GGPLMPOG_00657 547043.BIFPSEUDO_02725 2.51e-260 714.0 COG0263@1|root,COG0263@2|Bacteria,2GM8U@201174|Actinobacteria,4CZ2B@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate proB GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,PUA GGPLMPOG_00658 547043.BIFPSEUDO_02724 1.64e-296 810.0 COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,4CZFY@85004|Bifidobacteriales 201174|Actinobacteria E DegT/DnrJ/EryC1/StrS aminotransferase family aspC - 2.6.1.1,2.6.1.2,2.6.1.66 ko:K00812,ko:K08969,ko:K14260 ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00034 R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052,R07396 RC00006,RC00008,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 GGPLMPOG_00660 547043.BIFPSEUDO_02722 3.48e-44 143.0 COG0690@1|root,COG0690@2|Bacteria,2HZQC@201174|Actinobacteria,4D18K@85004|Bifidobacteriales 201174|Actinobacteria U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation secE - - ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecE GGPLMPOG_00661 547043.BIFPSEUDO_02721 3.23e-177 495.0 COG0250@1|root,COG0250@2|Bacteria,2GJFW@201174|Actinobacteria,4CYSH@85004|Bifidobacteriales 201174|Actinobacteria K Participates in transcription elongation, termination and antitermination nusG GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K02601 - - - - ko00000,ko03009,ko03021 - - - NusG GGPLMPOG_00662 547043.BIFPSEUDO_02720 5.21e-95 279.0 COG0080@1|root,COG0080@2|Bacteria,2IFCK@201174|Actinobacteria,4D0PA@85004|Bifidobacteriales 201174|Actinobacteria J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors rplK GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02867 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L11,Ribosomal_L11_N GGPLMPOG_00663 547043.BIFPSEUDO_02719 1.18e-157 442.0 COG0081@1|root,COG0081@2|Bacteria,2GM51@201174|Actinobacteria,4CZFR@85004|Bifidobacteriales 201174|Actinobacteria J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release rplA GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02863 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L1 GGPLMPOG_00664 547043.BIFPSEUDO_02718 4.85e-185 514.0 COG2508@1|root,COG2508@2|Bacteria,2GN0S@201174|Actinobacteria,4CYXU@85004|Bifidobacteriales 201174|Actinobacteria QT PucR C-terminal helix-turn-helix domain - - - - - - - - - - - - HTH_30 GGPLMPOG_00665 547043.BIFPSEUDO_02717 0.0 1436.0 2DX0J@1|root,342TV@2|Bacteria,2H683@201174|Actinobacteria,4CZAG@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_00666 547043.BIFPSEUDO_02716 2.53e-206 571.0 COG0340@1|root,COG0340@2|Bacteria,2GN8Q@201174|Actinobacteria,4D0R8@85004|Bifidobacteriales 201174|Actinobacteria H Biotin/lipoate A/B protein ligase family birA - 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB GGPLMPOG_00667 547043.BIFPSEUDO_02715 1.14e-115 333.0 COG1268@1|root,COG1268@2|Bacteria,2GJ53@201174|Actinobacteria,4D0BB@85004|Bifidobacteriales 201174|Actinobacteria S BioY family bioY - - ko:K03523 ko02010,map02010 M00581,M00582 - - ko00000,ko00001,ko00002,ko02000 2.A.88.1,2.A.88.2 - - BioY GGPLMPOG_00668 547043.BIFPSEUDO_02714 0.0 1247.0 COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria,4CYU4@85004|Bifidobacteriales 201174|Actinobacteria I Carbamoyl-phosphate synthase L chain, ATP binding domain protein accC - 6.3.4.14,6.4.1.2,6.4.1.3 ko:K11263 ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00741 R00742,R01859,R04385 RC00040,RC00097,RC00253,RC00367,RC00609 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2 GGPLMPOG_00669 547043.BIFPSEUDO_02713 0.0 1077.0 COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4CYSI@85004|Bifidobacteriales 201174|Actinobacteria I Carboxyl transferase domain pccB - - - - - - - - - - - Carboxyl_trans GGPLMPOG_00670 566552.BIFCAT_01622 0.0 5860.0 COG0304@1|root,COG0331@1|root,COG2030@1|root,COG4981@1|root,COG0304@2|Bacteria,COG0331@2|Bacteria,COG2030@2|Bacteria,COG4981@2|Bacteria,2GIY4@201174|Actinobacteria,4CYXJ@85004|Bifidobacteriales 201174|Actinobacteria I Beta-ketoacyl synthase, C-terminal domain fas - - ko:K11533 ko00061,ko01100,ko01212,ko04931,map00061,map01100,map01212,map04931 M00082,M00083 R01624,R01626,R04355,R04428,R04429,R04533,R04534,R04535,R04536,R04537,R04543,R04544,R04566,R04568,R04724,R04726,R04952,R04953,R04954,R04955,R04957,R04958,R04960,R04961,R04963,R04964,R04965,R04966,R04968,R04969,R07762,R07763,R07764,R07765,R10700 RC00004,RC00029,RC00039,RC00052,RC00076,RC00117,RC00831,RC01095,RC02727,RC02728,RC02729,RC02857,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyl_transf_1,DUF1729,Ketoacyl-synt_C,MaoC_dehydratas,SAT,ketoacyl-synt GGPLMPOG_00671 547043.BIFPSEUDO_02710 1.77e-107 309.0 COG0736@1|root,COG0736@2|Bacteria,2HZNB@201174|Actinobacteria,4D10J@85004|Bifidobacteriales 201174|Actinobacteria I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein acpS - 2.7.8.7 ko:K00997 ko00770,map00770 - R01625 RC00002 ko00000,ko00001,ko01000 - - - ACPS GGPLMPOG_00672 547043.BIFPSEUDO_02708 0.0 1239.0 COG0366@1|root,COG0366@2|Bacteria,2GKT9@201174|Actinobacteria,4CYRW@85004|Bifidobacteriales 201174|Actinobacteria G Alpha amylase, catalytic domain ams - 2.4.1.4 ko:K05341 ko00500,map00500 - R01823 RC00028 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase GGPLMPOG_00674 547043.BIFPSEUDO_02706 7.68e-151 425.0 2B37S@1|root,31VVT@2|Bacteria,2IDBE@201174|Actinobacteria,4CZJV@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_00675 1435051.BMOU_1646 2.04e-56 175.0 COG0184@1|root,COG0184@2|Bacteria,2IQA0@201174|Actinobacteria,4D10E@85004|Bifidobacteriales 201174|Actinobacteria J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome rpsO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - ko:K02956 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S15 GGPLMPOG_00677 1680.BADO_1070 2.02e-154 434.0 COG2801@1|root,COG2801@2|Bacteria,2H928@201174|Actinobacteria,4CZCP@85004|Bifidobacteriales 201174|Actinobacteria L Integrase core domain - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve,rve_2 GGPLMPOG_00678 78346.BRUM_0813 4.77e-93 276.0 COG2963@1|root,COG2963@2|Bacteria,2IF4K@201174|Actinobacteria,4D0JP@85004|Bifidobacteriales 201174|Actinobacteria L Helix-turn-helix domain - - - - - - - - - - - - HTH_23,HTH_28 GGPLMPOG_00683 1680.BADO_1228 1.61e-31 117.0 2CA4H@1|root,3342S@2|Bacteria,2GRNF@201174|Actinobacteria,4D1E9@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_00685 547043.BIFPSEUDO_03622 5.36e-161 451.0 COG1136@1|root,COG1136@2|Bacteria,2GJQV@201174|Actinobacteria,4CYT2@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran GGPLMPOG_00686 547043.BIFPSEUDO_03621 0.0 1136.0 COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2GJHB@201174|Actinobacteria,4CZC5@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD - 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N GGPLMPOG_00687 547043.BIFPSEUDO_03620 3.2e-157 440.0 COG1011@1|root,COG1011@2|Bacteria,2I8XE@201174|Actinobacteria,4D00B@85004|Bifidobacteriales 201174|Actinobacteria S Haloacid dehalogenase-like hydrolase - - 3.8.1.2 ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - HAD_2 GGPLMPOG_00688 547043.BIFPSEUDO_03619 5.87e-180 501.0 COG5658@1|root,COG5658@2|Bacteria,2ID8C@201174|Actinobacteria,4D18Z@85004|Bifidobacteriales 201174|Actinobacteria S SdpI/YhfL protein family - - - - - - - - - - - - DUF1648,SdpI GGPLMPOG_00689 547043.BIFPSEUDO_03618 6.64e-67 203.0 COG0640@1|root,COG0640@2|Bacteria,2IM1K@201174|Actinobacteria,4D14N@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn_helix, Arsenical Resistance Operon Repressor - - - - - - - - - - - - HTH_20,HTH_5 GGPLMPOG_00690 547043.BIFPSEUDO_03617 3.66e-157 440.0 COG0110@1|root,COG0110@2|Bacteria,2GNUB@201174|Actinobacteria,4CZ5H@85004|Bifidobacteriales 201174|Actinobacteria S Maltose acetyltransferase - - 2.3.1.18,2.3.1.79 ko:K00633,ko:K00661 - - - - ko00000,ko01000 - - - Hexapep,Hexapep_2,Mac GGPLMPOG_00691 547043.BIFPSEUDO_03616 1.33e-278 760.0 COG0620@1|root,COG0620@2|Bacteria,2I9RI@201174|Actinobacteria,4CZKN@85004|Bifidobacteriales 201174|Actinobacteria E Psort location Cytoplasmic, score 8.87 - - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 GGPLMPOG_00692 547043.BIFPSEUDO_03615 4.36e-89 262.0 COG0394@1|root,COG0394@2|Bacteria,2IHR3@201174|Actinobacteria,4D1A6@85004|Bifidobacteriales 201174|Actinobacteria T Belongs to the low molecular weight phosphotyrosine protein phosphatase family arsC - 1.20.4.1,2.8.4.2 ko:K03741,ko:K18701 - - - - ko00000,ko01000 - - - LMWPc GGPLMPOG_00693 547043.BIFPSEUDO_03614 9.59e-141 396.0 COG1670@1|root,COG1670@2|Bacteria,2HZBU@201174|Actinobacteria,4CZN2@85004|Bifidobacteriales 201174|Actinobacteria J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3 GGPLMPOG_00694 547043.BIFPSEUDO_03613 0.0 1754.0 COG0352@1|root,COG0422@1|root,COG0352@2|Bacteria,COG0422@2|Bacteria,2GJ3Y@201174|Actinobacteria,4D2W5@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction thiC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016020,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0040007,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 ko:K03147 ko00730,ko01100,map00730,map01100 M00127 R03472 RC03251,RC03252 ko00000,ko00001,ko00002,ko01000 - - - ThiC-associated,ThiC_Rad_SAM GGPLMPOG_00695 547043.BIFPSEUDO_03611 6.03e-210 580.0 COG0583@1|root,COG0583@2|Bacteria,2HZCU@201174|Actinobacteria,4CZT8@85004|Bifidobacteriales 201174|Actinobacteria K Bacterial regulatory helix-turn-helix protein, lysR family - - - - - - - - - - - - HTH_1,LysR_substrate GGPLMPOG_00696 547043.BIFPSEUDO_03610 9.36e-160 448.0 COG0461@1|root,COG0461@2|Bacteria,2GM5A@201174|Actinobacteria,4CZHB@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) pyrE - 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 - - - Pribosyltran GGPLMPOG_00697 547043.BIFPSEUDO_03609 8.22e-230 633.0 COG0167@1|root,COG0167@2|Bacteria,2GKC6@201174|Actinobacteria,4CYU2@85004|Bifidobacteriales 201174|Actinobacteria F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily pyrD - 1.3.1.14 ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01869 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh GGPLMPOG_00698 547043.BIFPSEUDO_03608 5.08e-198 548.0 COG0543@1|root,COG0543@2|Bacteria,2HQ24@201174|Actinobacteria,4CZC1@85004|Bifidobacteriales 201174|Actinobacteria C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B pyrK - - ko:K02823 ko00240,ko01100,map00240,map01100 - - - ko00000,ko00001 - - - DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1 GGPLMPOG_00699 547043.BIFPSEUDO_03607 1.44e-228 629.0 COG0284@1|root,COG0284@2|Bacteria,2GKWK@201174|Actinobacteria,4CZAK@85004|Bifidobacteriales 201174|Actinobacteria F Belongs to the OMP decarboxylase family. Type 2 subfamily pyrF - 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase GGPLMPOG_00700 547043.BIFPSEUDO_03606 0.0 951.0 COG0044@1|root,COG0044@2|Bacteria,2GJ0T@201174|Actinobacteria,4CZIW@85004|Bifidobacteriales 201174|Actinobacteria F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily pyrC GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 GGPLMPOG_00701 547043.BIFPSEUDO_03605 1.06e-96 281.0 COG1781@1|root,COG1781@2|Bacteria,2IFDF@201174|Actinobacteria,4D0QN@85004|Bifidobacteriales 201174|Actinobacteria F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein pyrI - - ko:K00610 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002 - - - PyrI,PyrI_C GGPLMPOG_00702 547043.BIFPSEUDO_03604 8.48e-241 662.0 COG0540@1|root,COG0540@2|Bacteria,2GKNA@201174|Actinobacteria,4CYZR@85004|Bifidobacteriales 201174|Actinobacteria F Belongs to the ATCase OTCase family pyrB - 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N GGPLMPOG_00703 566552.BIFCAT_00848 0.0 1987.0 COG1391@1|root,COG1391@2|Bacteria,2GJ91@201174|Actinobacteria,4CYQE@85004|Bifidobacteriales 201174|Actinobacteria H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell glnE GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698 2.7.7.42,2.7.7.89 ko:K00982 - - - - ko00000,ko01000 - - - GlnD_UR_UTase,GlnE GGPLMPOG_00704 547043.BIFPSEUDO_03602 5.54e-200 553.0 COG0685@1|root,COG0685@2|Bacteria,2GJTN@201174|Actinobacteria,4CZ22@85004|Bifidobacteriales 201174|Actinobacteria E Methylenetetrahydrofolate reductase metF - 1.5.1.20 ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 - - - MTHFR GGPLMPOG_00705 547043.BIFPSEUDO_03601 0.0 1521.0 COG0620@1|root,COG0620@2|Bacteria,2GIXA@201174|Actinobacteria,4CYWM@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation metE GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0040007,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_1,Meth_synt_2 GGPLMPOG_00706 547043.BIFPSEUDO_03600 1.67e-128 365.0 COG2062@1|root,COG2062@2|Bacteria,2GJ0I@201174|Actinobacteria,4D05N@85004|Bifidobacteriales 201174|Actinobacteria T Phosphoglycerate mutase family sixA - - ko:K08296 - - - - ko00000,ko01000 - - - His_Phos_1 GGPLMPOG_00707 547043.BIFPSEUDO_03599 9.73e-254 696.0 COG2519@1|root,COG2519@2|Bacteria,2GJPD@201174|Actinobacteria,4CYUG@85004|Bifidobacteriales 201174|Actinobacteria J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA trmI GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0031515,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.219,2.1.1.220 ko:K07442 - - - - ko00000,ko01000,ko03016 - - - GCD14,GCD14_N GGPLMPOG_00708 547043.BIFPSEUDO_03598 2.73e-203 562.0 COG1119@1|root,COG1119@2|Bacteria,2GIXX@201174|Actinobacteria,4CZDS@85004|Bifidobacteriales 201174|Actinobacteria P ATPases associated with a variety of cellular activities ylmA - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran GGPLMPOG_00709 547043.BIFPSEUDO_03596 0.0 862.0 COG0297@1|root,COG0297@2|Bacteria,2I2EE@201174|Actinobacteria,4CZKY@85004|Bifidobacteriales 201174|Actinobacteria G Starch synthase catalytic domain glgA GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901576 2.4.1.342 ko:K16148 ko00500,ko01100,map00500,map01100 - R02421,R11530 RC00005,RC00049,RC02748 ko00000,ko00001,ko01000,ko01003 - GT4 - Glyco_transf_4,Glycos_transf_1 GGPLMPOG_00710 401473.BDP_1080 3.85e-98 286.0 2BI32@1|root,32C84@2|Bacteria,2IDD6@201174|Actinobacteria,4D0PC@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - PsbJ GGPLMPOG_00711 547043.BIFPSEUDO_03594 0.0 1051.0 COG0493@1|root,COG0493@2|Bacteria,2GJ0A@201174|Actinobacteria,4CZ7B@85004|Bifidobacteriales 201174|Actinobacteria C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster gltD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - iNJ661.Rv3858c Fer4_20,Pyr_redox_2 GGPLMPOG_00712 547043.BIFPSEUDO_03593 0.0 3039.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,2GN09@201174|Actinobacteria,4CZB8@85004|Bifidobacteriales 201174|Actinobacteria E glutamate synthase NADPH large subunit gltB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 - R00021,R00093,R00114,R00248,R10086 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase GGPLMPOG_00713 547043.BIFPSEUDO_03592 3.31e-299 820.0 COG2233@1|root,COG2233@2|Bacteria,2GV9H@201174|Actinobacteria,4CZYX@85004|Bifidobacteriales 201174|Actinobacteria F Psort location CytoplasmicMembrane, score 10.00 - - - - - - - - - - - - Xan_ur_permease GGPLMPOG_00714 547043.BIFPSEUDO_03591 3.03e-277 757.0 COG1541@1|root,COG1541@2|Bacteria,2HZHX@201174|Actinobacteria,4D0HV@85004|Bifidobacteriales 201174|Actinobacteria H long-chain-fatty-acid--luciferin-component ligase, acyl-protein synthase - - - - - - - - - - - - LuxE GGPLMPOG_00715 547043.BIFPSEUDO_03590 0.0 991.0 COG1012@1|root,COG1012@2|Bacteria,2HZAQ@201174|Actinobacteria,4CZDA@85004|Bifidobacteriales 201174|Actinobacteria C Acyl-CoA reductase (LuxC) - - - - - - - - - - - - LuxC GGPLMPOG_00716 547043.BIFPSEUDO_03589 3.98e-187 520.0 COG1028@1|root,COG1028@2|Bacteria,2GIX2@201174|Actinobacteria,4D0FH@85004|Bifidobacteriales 201174|Actinobacteria IQ Oxidoreductase, short chain dehydrogenase reductase family protein - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 GGPLMPOG_00717 547043.BIFPSEUDO_03588 3.15e-298 812.0 COG0635@1|root,COG0635@2|Bacteria,2GJXX@201174|Actinobacteria,4CZ81@85004|Bifidobacteriales 201174|Actinobacteria H Involved in the biosynthesis of porphyrin-containing compound hemN GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - - - - - - - - - iNJ661.Rv2388c HemN_C,Radical_SAM GGPLMPOG_00718 547043.BIFPSEUDO_03586 0.0 1237.0 COG0481@1|root,COG0481@2|Bacteria,2GJAB@201174|Actinobacteria,4CYWI@85004|Bifidobacteriales 201174|Actinobacteria M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C GGPLMPOG_00719 547043.BIFPSEUDO_03585 7.89e-46 148.0 COG0268@1|root,COG0268@2|Bacteria,2IQ73@201174|Actinobacteria,4D18U@85004|Bifidobacteriales 201174|Actinobacteria J Binds directly to 16S ribosomal RNA rpsT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - ko:K02968 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S20p GGPLMPOG_00720 547043.BIFPSEUDO_03584 3.02e-174 486.0 COG2860@1|root,COG2860@2|Bacteria,2GMI4@201174|Actinobacteria,4CZ51@85004|Bifidobacteriales 201174|Actinobacteria S UPF0126 domain - - - - - - - - - - - - UPF0126 GGPLMPOG_00721 547043.BIFPSEUDO_03582 8.14e-290 789.0 COG0115@1|root,COG0115@2|Bacteria,2GKJ1@201174|Actinobacteria,4CZD9@85004|Bifidobacteriales 201174|Actinobacteria E Amino-transferase class IV ilvE - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 GGPLMPOG_00723 547043.BIFPSEUDO_03580 2.37e-76 229.0 COG0454@1|root,COG0454@2|Bacteria,2I2G2@201174|Actinobacteria,4D0RY@85004|Bifidobacteriales 201174|Actinobacteria K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_7 GGPLMPOG_00724 547043.BIFPSEUDO_03579 1e-76 229.0 COG0239@1|root,COG0239@2|Bacteria,2IC26@201174|Actinobacteria,4D14T@85004|Bifidobacteriales 201174|Actinobacteria U Important for reducing fluoride concentration in the cell, thus reducing its toxicity crcB - - ko:K06199 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CRCB GGPLMPOG_00725 547043.BIFPSEUDO_03578 4.21e-121 345.0 COG0239@1|root,COG0239@2|Bacteria,2IJGQ@201174|Actinobacteria,4D11I@85004|Bifidobacteriales 201174|Actinobacteria D Important for reducing fluoride concentration in the cell, thus reducing its toxicity - - - ko:K06199 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CRCB GGPLMPOG_00726 547043.BIFPSEUDO_03576 1.29e-127 364.0 COG1825@1|root,COG1825@2|Bacteria,2GJPJ@201174|Actinobacteria,4CZ7W@85004|Bifidobacteriales 201174|Actinobacteria J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ctc GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02897 ko03010,map03010 M00178 - - ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L25p,Ribosomal_TL5_C GGPLMPOG_00727 547043.BIFPSEUDO_03575 1.08e-249 684.0 COG1073@1|root,COG1073@2|Bacteria,2HZEB@201174|Actinobacteria,4D02D@85004|Bifidobacteriales 201174|Actinobacteria S alpha beta - - - ko:K06889 - - - - ko00000 - - - Abhydrolase_6,Hydrolase_4 GGPLMPOG_00728 547043.BIFPSEUDO_03574 9.97e-36 121.0 COG0477@1|root,COG2814@2|Bacteria 2|Bacteria EGP Major facilitator Superfamily yhjX - - ko:K08177 - - - - ko00000,ko02000 2.A.1.11 - - MFS_1 GGPLMPOG_00729 547043.BIFPSEUDO_03573 3.74e-41 136.0 COG0477@1|root,COG2814@2|Bacteria 2|Bacteria EGP Major facilitator Superfamily - - - ko:K08177,ko:K19577 - - - - ko00000,ko02000 2.A.1.11,2.A.1.2.65 - - MFS_1 GGPLMPOG_00730 566552.BIFCAT_00932 0.0 1365.0 COG0178@1|root,COG0178@2|Bacteria,2GNMW@201174|Actinobacteria,4CZ5X@85004|Bifidobacteriales 201174|Actinobacteria L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate uvrA3 - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran GGPLMPOG_00731 566552.BIFCAT_00933 6.98e-241 661.0 COG0208@1|root,COG0208@2|Bacteria,2GK46@201174|Actinobacteria,4CYQ2@85004|Bifidobacteriales 201174|Actinobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0071704,GO:0090304,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_sm GGPLMPOG_00733 547043.BIFPSEUDO_03568 0.0 1419.0 COG0209@1|root,COG0209@2|Bacteria,2GKX9@201174|Actinobacteria,4CZF3@85004|Bifidobacteriales 201174|Actinobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdE GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005971,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016020,GO:0016491,GO:0016725,GO:0016728,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0051063,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0071944,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - RNR_N,Ribonuc_red_lgC,Ribonuc_red_lgN GGPLMPOG_00734 566552.BIFCAT_00935 1.55e-95 278.0 COG1780@1|root,COG1780@2|Bacteria,2IM4D@201174|Actinobacteria,4D0XV@85004|Bifidobacteriales 201174|Actinobacteria F Probably involved in ribonucleotide reductase function nrdI - - ko:K03647 - - - - ko00000 - - - Flavodoxin_NdrI GGPLMPOG_00735 566552.BIFCAT_00936 3.15e-50 159.0 COG0695@1|root,COG0695@2|Bacteria,2IRCP@201174|Actinobacteria,4D17U@85004|Bifidobacteriales 201174|Actinobacteria O Glutaredoxin nrdH - - ko:K06191 - - - - ko00000 - - - Glutaredoxin GGPLMPOG_00736 566552.BIFCAT_00938 2.06e-152 428.0 COG1309@1|root,COG1309@2|Bacteria,2HZJX@201174|Actinobacteria,4D0QJ@85004|Bifidobacteriales 201174|Actinobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N GGPLMPOG_00737 547043.BIFPSEUDO_03563 7.88e-287 786.0 COG2271@1|root,COG2271@2|Bacteria,2HZ9S@201174|Actinobacteria,4CZ4Z@85004|Bifidobacteriales 201174|Actinobacteria G Transmembrane secretion effector - - - - - - - - - - - - MFS_1 GGPLMPOG_00739 547043.BIFPSEUDO_03561 0.0 927.0 2ANBU@1|root,31DA7@2|Bacteria,2IAHJ@201174|Actinobacteria,4CYW4@85004|Bifidobacteriales 201174|Actinobacteria S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - - GGPLMPOG_00740 547043.BIFPSEUDO_03559 0.0 894.0 COG1282@1|root,COG1282@2|Bacteria,2GNKB@201174|Actinobacteria,4CZF5@85004|Bifidobacteriales 201174|Actinobacteria C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane pntB - 1.6.1.2 ko:K00325 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - PNTB GGPLMPOG_00741 1435051.BMOU_0956 1.02e-57 179.0 COG3288@1|root,COG3288@2|Bacteria,2IKR9@201174|Actinobacteria,4D12D@85004|Bifidobacteriales 201174|Actinobacteria C 4TM region of pyridine nucleotide transhydrogenase, mitoch pntAB - 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - PNTB_4TM GGPLMPOG_00742 547043.BIFPSEUDO_03557 6.91e-260 714.0 COG3288@1|root,COG3288@2|Bacteria,2I2FZ@201174|Actinobacteria,4CZZ3@85004|Bifidobacteriales 201174|Actinobacteria C NAD(P) transhydrogenase subunit alpha part 1 K00324 pntA - 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM GGPLMPOG_00743 547043.BIFPSEUDO_03556 0.0 1343.0 COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4CYYJ@85004|Bifidobacteriales 201174|Actinobacteria I AMP-binding enzyme fadD2 - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding GGPLMPOG_00744 566552.BIFCAT_00948 2.58e-228 630.0 COG1159@1|root,COG1159@2|Bacteria,2GJJE@201174|Actinobacteria,4CYZH@85004|Bifidobacteriales 201174|Actinobacteria S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism era GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - ko:K03595 - - - - ko00000,ko03009,ko03029 - - - KH_2,MMR_HSR1 GGPLMPOG_00745 547043.BIFPSEUDO_03554 0.0 869.0 COG1253@1|root,COG1253@2|Bacteria,2GIWR@201174|Actinobacteria,4CZ1W@85004|Bifidobacteriales 201174|Actinobacteria S CBS domain corC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - CBS,CorC_HlyC,DUF21 GGPLMPOG_00746 547043.BIFPSEUDO_03553 1.14e-133 378.0 COG0319@1|root,COG0319@2|Bacteria,2GMUF@201174|Actinobacteria,4CZJF@85004|Bifidobacteriales 201174|Actinobacteria S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ybeY - - ko:K07042 - - - - ko00000,ko03009 - - - UPF0054 GGPLMPOG_00747 547043.BIFPSEUDO_03552 2.86e-267 732.0 COG1702@1|root,COG1702@2|Bacteria,2GK0W@201174|Actinobacteria,4CZJH@85004|Bifidobacteriales 201174|Actinobacteria T PhoH-like protein phoH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K06217 - - - - ko00000 - - - PhoH GGPLMPOG_00748 547043.BIFPSEUDO_03551 8.96e-75 224.0 COG0537@1|root,COG0537@2|Bacteria,2IHPT@201174|Actinobacteria,4D130@85004|Bifidobacteriales 201174|Actinobacteria FG Scavenger mRNA decapping enzyme C-term binding hit - - ko:K02503 - - - - ko00000,ko04147 - - - DcpS_C,HIT GGPLMPOG_00749 547043.BIFPSEUDO_03550 9.78e-188 521.0 COG1385@1|root,COG1385@2|Bacteria,2GTKX@201174|Actinobacteria,4CZAD@85004|Bifidobacteriales 201174|Actinobacteria J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit - - 2.1.1.193 ko:K09761 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_RNA GGPLMPOG_00751 547043.BIFPSEUDO_03548 5e-207 573.0 COG0566@1|root,COG0566@2|Bacteria,2GJ12@201174|Actinobacteria,4CYQ6@85004|Bifidobacteriales 201174|Actinobacteria J SpoU rRNA Methylase family spoU2 - - - - - - - - - - - SpoU_methylase GGPLMPOG_00752 547043.BIFPSEUDO_03547 5.57e-310 843.0 COG0448@1|root,COG0448@2|Bacteria,2I2EF@201174|Actinobacteria,4CZ4E@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans glgC - 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase GGPLMPOG_00753 547043.BIFPSEUDO_03546 1.6e-140 396.0 COG2151@1|root,COG2151@2|Bacteria,2IKUH@201174|Actinobacteria,4CYRH@85004|Bifidobacteriales 201174|Actinobacteria S Iron-sulfur cluster assembly protein - - - - - - - - - - - - FeS_assembly_P GGPLMPOG_00754 547043.BIFPSEUDO_03544 5.22e-131 371.0 COG0822@1|root,COG0822@2|Bacteria,2IHY9@201174|Actinobacteria,4CZU5@85004|Bifidobacteriales 201174|Actinobacteria C SUF system FeS assembly protein, NifU family iscU - - ko:K04488 - - - - ko00000 - - - NifU_N GGPLMPOG_00755 547043.BIFPSEUDO_03543 4.38e-303 827.0 COG0520@1|root,COG0520@2|Bacteria,2GIVK@201174|Actinobacteria,4CZIU@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine sufS GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 - R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 - - - Aminotran_5 GGPLMPOG_00756 547043.BIFPSEUDO_03542 9.39e-183 508.0 COG0396@1|root,COG0396@2|Bacteria,2GKB7@201174|Actinobacteria,4CZU1@85004|Bifidobacteriales 201174|Actinobacteria O FeS assembly ATPase SufC sufC - - ko:K09013 - - - - ko00000,ko02000 - - - ABC_tran GGPLMPOG_00757 547043.BIFPSEUDO_03541 3.55e-298 813.0 COG0719@1|root,COG0719@2|Bacteria,2GJNV@201174|Actinobacteria,4CZEE@85004|Bifidobacteriales 201174|Actinobacteria O FeS assembly protein SufD sufD GO:0008150,GO:0009605,GO:0009607,GO:0040007,GO:0043207,GO:0044403,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136 - ko:K09015 - - - - ko00000 - - - UPF0051 GGPLMPOG_00758 566552.BIFCAT_00962 0.0 1002.0 COG0719@1|root,COG0719@2|Bacteria,2GKCZ@201174|Actinobacteria,4CZPQ@85004|Bifidobacteriales 201174|Actinobacteria O FeS assembly protein SufB sufB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - ko:K09014 - - - - ko00000 - - - UPF0051 GGPLMPOG_00759 547043.BIFPSEUDO_03539 0.0 1119.0 COG1376@1|root,COG1376@2|Bacteria,2GQ7D@201174|Actinobacteria,4CZ5A@85004|Bifidobacteriales 201174|Actinobacteria S L,D-transpeptidase catalytic domain - - - - - - - - - - - - PG_binding_4,YkuD GGPLMPOG_00760 547043.BIFPSEUDO_03538 0.0 1111.0 COG0504@1|root,COG0504@2|Bacteria,2GJ13@201174|Actinobacteria,4CYWE@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv1699 CTP_synth_N,GATase GGPLMPOG_00761 547043.BIFPSEUDO_03536 0.0 3481.0 COG0366@1|root,COG1523@1|root,COG0366@2|Bacteria,COG1523@2|Bacteria,2GKK1@201174|Actinobacteria,4D2UY@85004|Bifidobacteriales 201174|Actinobacteria M Aamy_C - - 3.2.1.1,3.2.1.41 ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 - R02108,R02111,R02112,R11262 - ko00000,ko00001,ko01000 - CBM48,GH13 - Alpha-amylase,Alpha-amylase_C,Big_4,CBM_25,CBM_48,DUF5011,PUD GGPLMPOG_00762 547043.BIFPSEUDO_03534 3.9e-105 303.0 COG0757@1|root,COG0757@2|Bacteria,2IMBY@201174|Actinobacteria,4D0Q6@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes a trans-dehydration via an enolate intermediate aroQ GO:0003674,GO:0003824,GO:0003855,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:1901576 4.2.1.10 ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03084 RC00848 ko00000,ko00001,ko00002,ko01000 - - - DHquinase_II GGPLMPOG_00763 547043.BIFPSEUDO_03533 0.0 1077.0 COG0337@1|root,COG0703@1|root,COG0337@2|Bacteria,COG0703@2|Bacteria,2GIUZ@201174|Actinobacteria,4CZ2G@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) aroB GO:0003674,GO:0003824,GO:0003856,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.71,4.2.3.4 ko:K01735,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412,R03083 RC00002,RC00078,RC00847 ko00000,ko00001,ko00002,ko01000 - - - DHQ_synthase,SKI GGPLMPOG_00764 547043.BIFPSEUDO_03532 1.64e-282 772.0 COG0082@1|root,COG0082@2|Bacteria,2GJJN@201174|Actinobacteria,4CZ43@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system aroC GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv2540c Chorismate_synt GGPLMPOG_00765 547043.BIFPSEUDO_03531 3.69e-95 279.0 2B59B@1|root,31Y3G@2|Bacteria,2GRM1@201174|Actinobacteria,4D110@85004|Bifidobacteriales 201174|Actinobacteria S Type IV leader peptidase family - - 3.4.23.43 ko:K02654 - M00331 - - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 3.A.15.2 - - Peptidase_A24 GGPLMPOG_00766 547043.BIFPSEUDO_03530 9.58e-253 697.0 COG1559@1|root,COG1559@2|Bacteria,2GKGQ@201174|Actinobacteria,4CZID@85004|Bifidobacteriales 201174|Actinobacteria S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation mltG - - ko:K07082 - - - - ko00000 - - - YceG GGPLMPOG_00767 547043.BIFPSEUDO_03529 1.06e-106 308.0 COG0816@1|root,COG0816@2|Bacteria,2IQB0@201174|Actinobacteria,4D0WQ@85004|Bifidobacteriales 201174|Actinobacteria L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ruvX GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K07447 - - - - ko00000,ko01000 - - - RuvX GGPLMPOG_00768 547043.BIFPSEUDO_03528 0.0 1754.0 COG0013@1|root,COG0013@2|Bacteria,2GIUG@201174|Actinobacteria,4CZQN@85004|Bifidobacteriales 201174|Actinobacteria J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD GGPLMPOG_00769 547043.BIFPSEUDO_03527 6.83e-50 158.0 2B9VR@1|root,3238X@2|Bacteria,2IQYT@201174|Actinobacteria,4D16I@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_00770 547043.BIFPSEUDO_03526 8.09e-79 235.0 COG4768@1|root,COG4768@2|Bacteria,2II1J@201174|Actinobacteria,4D0VH@85004|Bifidobacteriales 201174|Actinobacteria S Bacterial protein of unknown function (DUF948) - - - - - - - - - - - - DUF948 GGPLMPOG_00771 547043.BIFPSEUDO_03525 9.46e-167 465.0 COG0406@1|root,COG0406@2|Bacteria,2GK2I@201174|Actinobacteria,4CZH2@85004|Bifidobacteriales 201174|Actinobacteria G Phosphoglycerate mutase family - - 5.4.2.12 ko:K15634 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - - His_Phos_1 GGPLMPOG_00772 566552.BIFCAT_00976 1.3e-57 180.0 COG1950@1|root,COG1950@2|Bacteria,2HZND@201174|Actinobacteria,4D117@85004|Bifidobacteriales 201174|Actinobacteria S Mycobacterial 4 TMS phage holin, superfamily IV - - - ko:K08972 - - - - ko00000 - - - Phage_holin_4_2 GGPLMPOG_00773 547043.BIFPSEUDO_03523 3.17e-142 402.0 COG0522@1|root,COG0522@2|Bacteria,2GIRX@201174|Actinobacteria,4CYSP@85004|Bifidobacteriales 201174|Actinobacteria J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit rpsD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - ko:K02986 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S4,S4 GGPLMPOG_00774 547043.BIFPSEUDO_03522 6.08e-191 531.0 COG1136@1|root,COG1136@2|Bacteria,2IATV@201174|Actinobacteria,4CZMH@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran GGPLMPOG_00775 547043.BIFPSEUDO_03521 2.9e-275 754.0 COG0577@1|root,COG0577@2|Bacteria,2H8C2@201174|Actinobacteria,4CZB5@85004|Bifidobacteriales 201174|Actinobacteria V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD GGPLMPOG_00776 547043.BIFPSEUDO_03520 3.23e-80 239.0 2CBVU@1|root,3324G@2|Bacteria,2IKKE@201174|Actinobacteria,4D106@85004|Bifidobacteriales 201174|Actinobacteria S Domain of unknown function (DUF4418) - - - - - - - - - - - - DUF4418 GGPLMPOG_00777 547043.BIFPSEUDO_03519 0.0 1626.0 COG0210@1|root,COG0210@2|Bacteria,2GISS@201174|Actinobacteria,4CYRJ@85004|Bifidobacteriales 201174|Actinobacteria L DNA helicase pcrA GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C GGPLMPOG_00778 547043.BIFPSEUDO_03518 1.54e-137 389.0 COG0503@1|root,COG0503@2|Bacteria,2GJ3S@201174|Actinobacteria,4CYSZ@85004|Bifidobacteriales 201174|Actinobacteria F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis xpt - 2.4.2.22 ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 - R01229,R02142 RC00063,RC00122 ko00000,ko00001,ko01000 - - - Pribosyltran GGPLMPOG_00779 547043.BIFPSEUDO_03517 6.08e-312 852.0 COG2233@1|root,COG2233@2|Bacteria,2GMH6@201174|Actinobacteria,4CZ9F@85004|Bifidobacteriales 201174|Actinobacteria F Permease family pbuX - - ko:K03458 - - - - ko00000 2.A.40 - - Xan_ur_permease GGPLMPOG_00780 547043.BIFPSEUDO_03516 0.0 1224.0 COG1835@1|root,COG1835@2|Bacteria,2GKI5@201174|Actinobacteria,4D0BY@85004|Bifidobacteriales 201174|Actinobacteria I Psort location CytoplasmicMembrane, score 9.99 yrhL - - - - - - - - - - - Acyl_transf_3 GGPLMPOG_00781 547043.BIFPSEUDO_03515 8.03e-296 807.0 COG0282@1|root,COG0282@2|Bacteria,2GJAW@201174|Actinobacteria,4CZ7V@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction ackA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv0409 Acetate_kinase GGPLMPOG_00782 547043.BIFPSEUDO_03514 0.0 1048.0 COG0280@1|root,COG0280@2|Bacteria,2GJ5U@201174|Actinobacteria,4CZE6@85004|Bifidobacteriales 201174|Actinobacteria C phosphate acetyltransferase pta GO:0005575,GO:0005576 2.3.1.8 ko:K13788 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00230,R00921 RC00004,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000 - - - AAA_26,DRTGG,PTA_PTB GGPLMPOG_00783 547043.BIFPSEUDO_03513 0.0 1695.0 COG3957@1|root,COG3957@2|Bacteria,2GN27@201174|Actinobacteria,4CZT5@85004|Bifidobacteriales 201174|Actinobacteria G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase xfp - 4.1.2.22,4.1.2.9 ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 - R00761,R01621 RC00032,RC00226 ko00000,ko00001,ko01000 - - - XFP,XFP_C,XFP_N GGPLMPOG_00784 547043.BIFPSEUDO_03510 0.0 1038.0 COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,2GM09@201174|Actinobacteria,4CZC3@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the synthesis of GMP from XMP guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase,GMP_synt_C,NAD_synthase GGPLMPOG_00785 547043.BIFPSEUDO_03500 3.28e-100 290.0 COG0454@1|root,COG0456@2|Bacteria,2GUUC@201174|Actinobacteria,4D1I5@85004|Bifidobacteriales 201174|Actinobacteria K Acetyltransferase (GNAT) domain - - - ko:K03826 - - - - ko00000,ko01000 - - - Acetyltransf_10 GGPLMPOG_00786 547043.BIFPSEUDO_03499 4.56e-93 272.0 COG0454@1|root,COG0456@2|Bacteria,2IPKP@201174|Actinobacteria,4D2TY@85004|Bifidobacteriales 201174|Actinobacteria K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_7 GGPLMPOG_00787 547043.BIFPSEUDO_03494 0.0 880.0 COG0128@1|root,COG0128@2|Bacteria,2GJKX@201174|Actinobacteria,4CZBG@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate aroA GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:0071944,GO:1901576 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 - - - EPSP_synthase GGPLMPOG_00789 547043.BIFPSEUDO_03492 3.23e-269 738.0 2DSXT@1|root,32UTZ@2|Bacteria,2GKR7@201174|Actinobacteria,4CZBW@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - DUF998 GGPLMPOG_00790 547043.BIFPSEUDO_03491 0.0 1463.0 COG1523@1|root,COG1523@2|Bacteria,2GJ00@201174|Actinobacteria,4CZGR@85004|Bifidobacteriales 201174|Actinobacteria G Belongs to the glycosyl hydrolase 13 family glgX - 3.2.1.68 ko:K01214 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R09995,R11261 - ko00000,ko00001,ko00002,ko01000 - CBM48,GH13 - Alpha-amylase,CBM_48 GGPLMPOG_00791 547043.BIFPSEUDO_03490 4.34e-159 445.0 COG0494@1|root,COG0494@2|Bacteria,2IIY0@201174|Actinobacteria,4D0P8@85004|Bifidobacteriales 201174|Actinobacteria L NUDIX domain - - - - - - - - - - - - NUDIX GGPLMPOG_00792 547043.BIFPSEUDO_03489 3.51e-222 612.0 COG0327@1|root,COG0327@2|Bacteria,2GKHZ@201174|Actinobacteria,4CYXC@85004|Bifidobacteriales 201174|Actinobacteria L NIF3 (NGG1p interacting factor 3) - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - - - - - - - - - - NIF3 GGPLMPOG_00793 547043.BIFPSEUDO_03488 0.0 1817.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2GJY2@201174|Actinobacteria,4CYVK@85004|Bifidobacteriales 201174|Actinobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 GGPLMPOG_00794 547043.BIFPSEUDO_03487 8.64e-156 440.0 COG3707@1|root,COG3707@2|Bacteria,2GK7T@201174|Actinobacteria,4CYS7@85004|Bifidobacteriales 201174|Actinobacteria T Response regulator receiver domain protein pdtaR GO:0000160,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016020,GO:0023052,GO:0030312,GO:0035556,GO:0040007,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071944 - ko:K22010 - M00839 - - ko00000,ko00002,ko02022 - - - ANTAR,Response_reg GGPLMPOG_00795 547043.BIFPSEUDO_03486 4.26e-208 578.0 COG0676@1|root,COG0676@2|Bacteria,2IIUH@201174|Actinobacteria,4CZWN@85004|Bifidobacteriales 201174|Actinobacteria G Aldose 1-epimerase - - 5.1.3.15 ko:K01792 ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130 - R02739 RC00563 ko00000,ko00001,ko01000 - - - Aldose_epim GGPLMPOG_00796 334413.FMG_1375 3.56e-133 388.0 COG4974@1|root,COG4974@2|Bacteria,1TQXV@1239|Firmicutes,24884@186801|Clostridia,22IEW@1570339|Peptoniphilaceae 186801|Clostridia L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_int_SAM_4,Phage_integrase GGPLMPOG_00797 1236518.BAKP01000082_gene2703 3.95e-85 268.0 COG0732@1|root,COG0732@2|Bacteria,4NQZY@976|Bacteroidetes 976|Bacteroidetes V type i restriction - - 3.1.21.3 ko:K01154 - - - - ko00000,ko01000,ko02048 - - - Methylase_S GGPLMPOG_00798 883110.HMPREF9260_01068 7.08e-73 224.0 COG0732@1|root,COG0732@2|Bacteria,1UXXZ@1239|Firmicutes 1239|Firmicutes V Type I restriction modification DNA specificity domain - - - - - - - - - - - - Methylase_S GGPLMPOG_00799 471855.Shel_17670 1.82e-305 839.0 COG0286@1|root,COG0286@2|Bacteria,2GKAQ@201174|Actinobacteria,4CURP@84998|Coriobacteriia 84998|Coriobacteriia V HsdM N-terminal domain hsdM - 2.1.1.72 ko:K03427 - - - - ko00000,ko01000,ko02048 - - - HsdM_N,N6_Mtase GGPLMPOG_00800 471855.Shel_17680 0.0 1686.0 COG0610@1|root,COG0610@2|Bacteria,2HI69@201174|Actinobacteria,4CVYG@84998|Coriobacteriia 84998|Coriobacteriia L Subunit R is required for both nuclease and ATPase activities, but not for modification - - 3.1.21.3 ko:K01153 - - - - ko00000,ko01000,ko02048 - - - DUF3387,HSDR_N,ResIII GGPLMPOG_00801 1193128.A200_05257 1.68e-44 157.0 COG0210@1|root,COG0210@2|Bacteria,2H52U@201174|Actinobacteria 201174|Actinobacteria F DNA helicase - - - - - - - - - - - - - GGPLMPOG_00802 401473.BDP_0700 1.57e-132 378.0 COG0765@1|root,COG0765@2|Bacteria,2GJJ9@201174|Actinobacteria,4CZIX@85004|Bifidobacteriales 201174|Actinobacteria E Binding-protein-dependent transport system inner membrane component tcyA/tcyB - - ko:K02029,ko:K02030,ko:K02424,ko:K10009 ko02010,map02010 M00234,M00236 - - ko00000,ko00001,ko00002,ko02000,ko02035 3.A.1.3,3.A.1.3.10,3.A.1.3.14 - - BPD_transp_1,SBP_bac_3 GGPLMPOG_00803 78346.BRUM_1281 9.14e-158 446.0 COG0834@1|root,COG0834@2|Bacteria,2GJQW@201174|Actinobacteria,4D0FX@85004|Bifidobacteriales 201174|Actinobacteria ET Bacterial periplasmic substrate-binding proteins - - - ko:K02424 ko02010,map02010 M00234 - - ko00000,ko00001,ko00002,ko02000,ko02035 3.A.1.3.10,3.A.1.3.14 - - SBP_bac_3 GGPLMPOG_00804 78346.BRUM_1282 2.03e-145 415.0 COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria,4D0CN@85004|Bifidobacteriales 201174|Actinobacteria E ATPases associated with a variety of cellular activities ehuA - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran GGPLMPOG_00805 78346.BRUM_1283 2.9e-247 684.0 COG0626@1|root,COG0626@2|Bacteria,2GJ5S@201174|Actinobacteria,4CZKK@85004|Bifidobacteriales 201174|Actinobacteria E Cys/Met metabolism PLP-dependent enzyme metC1 - 4.4.1.8 ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP GGPLMPOG_00807 552531.BIF_02196 1.44e-25 97.4 COG3077@1|root,COG3077@2|Bacteria,2GV25@201174|Actinobacteria,4D179@85004|Bifidobacteriales 201174|Actinobacteria L RelB antitoxin - - - ko:K07473 - - - - ko00000,ko02048 - - - RelB GGPLMPOG_00809 547043.BIFPSEUDO_03481 0.0 1047.0 COG0469@1|root,COG0469@2|Bacteria,2GJY8@201174|Actinobacteria,4CZA8@85004|Bifidobacteriales 201174|Actinobacteria G Pyruvate kinase pyk GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PK,PK_C GGPLMPOG_00810 547043.BIFPSEUDO_03480 2.78e-225 622.0 COG0861@1|root,COG0861@2|Bacteria,2GIWU@201174|Actinobacteria,4CYW2@85004|Bifidobacteriales 201174|Actinobacteria P Integral membrane protein, TerC family terC - - ko:K05794 - - - - ko00000 - - - TerC GGPLMPOG_00811 547043.BIFPSEUDO_03479 0.0 1368.0 COG0556@1|root,COG0556@2|Bacteria,2GJ03@201174|Actinobacteria,4CZR0@85004|Bifidobacteriales 201174|Actinobacteria L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB GO:0002682,GO:0002684,GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136 - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB GGPLMPOG_00812 547043.BIFPSEUDO_03478 1.09e-149 422.0 COG0237@1|root,COG0237@2|Bacteria,2GN96@201174|Actinobacteria,4D0PG@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A coaE GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - CoaE,GrpB GGPLMPOG_00813 547043.BIFPSEUDO_03477 0.0 905.0 COG0539@1|root,COG0539@2|Bacteria,2GJAK@201174|Actinobacteria,4CZ6S@85004|Bifidobacteriales 201174|Actinobacteria J Ribosomal protein S1 rpsA GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 GGPLMPOG_00814 547043.BIFPSEUDO_03476 3.88e-207 573.0 COG0190@1|root,COG0190@2|Bacteria,2GJZS@201174|Actinobacteria,4CZ53@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0040007,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - - THF_DHG_CYH,THF_DHG_CYH_C GGPLMPOG_00815 547043.BIFPSEUDO_03475 9.56e-230 636.0 COG0803@1|root,COG0803@2|Bacteria,2GM1K@201174|Actinobacteria,4CZ99@85004|Bifidobacteriales 201174|Actinobacteria P Zinc-uptake complex component A periplasmic - - - ko:K02077 - M00244 - - ko00000,ko00002,ko02000 3.A.1.15 - - ZnuA GGPLMPOG_00816 547043.BIFPSEUDO_03474 7.98e-205 567.0 COG1121@1|root,COG1121@2|Bacteria,2GP3A@201174|Actinobacteria,4CZEV@85004|Bifidobacteriales 201174|Actinobacteria P ATPases associated with a variety of cellular activities - - - ko:K02074 - M00244 - - ko00000,ko00002,ko02000 3.A.1.15 - - ABC_tran GGPLMPOG_00817 547043.BIFPSEUDO_03473 6.17e-177 495.0 COG1108@1|root,COG1108@2|Bacteria,2GJ7H@201174|Actinobacteria,4CYTG@85004|Bifidobacteriales 201174|Actinobacteria U ABC 3 transport family znuB - - ko:K02075 - M00244 - - ko00000,ko00002,ko02000 3.A.1.15 - - ABC-3 GGPLMPOG_00818 547043.BIFPSEUDO_03472 3.22e-114 327.0 COG0245@1|root,COG0245@2|Bacteria,2II8H@201174|Actinobacteria,4D0X6@85004|Bifidobacteriales 201174|Actinobacteria H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) ispF - 2.7.7.60,4.6.1.12 ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05633,R05637 RC00002,RC01440 ko00000,ko00001,ko00002,ko01000 - - - IspD,YgbB GGPLMPOG_00819 547043.BIFPSEUDO_03471 8.46e-133 377.0 COG1329@1|root,COG1329@2|Bacteria,2GKSU@201174|Actinobacteria,4CZXD@85004|Bifidobacteriales 201174|Actinobacteria K CarD-like/TRCF domain carD GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0040007,GO:0042594,GO:0044419,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - ko:K07736 - - - - ko00000,ko03000 - - - CarD_CdnL_TRCF GGPLMPOG_00820 547043.BIFPSEUDO_03470 0.0 1588.0 COG0296@1|root,COG0296@2|Bacteria,2GJ5C@201174|Actinobacteria,4CZMD@85004|Bifidobacteriales 201174|Actinobacteria G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position glgB GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0055114,GO:0071704,GO:0071944,GO:1901576 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000,ko04147 - CBM48,GH13 - Alpha-amylase,Alpha-amylase_C,CBM_48 GGPLMPOG_00821 547043.BIFPSEUDO_03469 1.74e-165 463.0 COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria,4CZS5@85004|Bifidobacteriales 201174|Actinobacteria T Response regulator receiver domain protein cseB - - - - - - - - - - - Response_reg,Trans_reg_C GGPLMPOG_00822 547043.BIFPSEUDO_03468 1.99e-238 658.0 COG5002@1|root,COG5002@2|Bacteria,2GIX7@201174|Actinobacteria,4CZNA@85004|Bifidobacteriales 201174|Actinobacteria T ATPase histidine kinase DNA gyrase B HSP90 domain protein - - - - - - - - - - - - HAMP,HATPase_c,HisKA GGPLMPOG_00823 547043.BIFPSEUDO_03467 6.89e-180 500.0 COG1040@1|root,COG1040@2|Bacteria,2I9PA@201174|Actinobacteria,4D11A@85004|Bifidobacteriales 201174|Actinobacteria S Phosphoribosyl transferase domain pyrE_1 - - - - - - - - - - - Pribosyltran GGPLMPOG_00824 547043.BIFPSEUDO_03466 2.99e-195 542.0 COG0561@1|root,COG0561@2|Bacteria,2HZD0@201174|Actinobacteria,4CZ4N@85004|Bifidobacteriales 201174|Actinobacteria T Eukaryotic phosphomannomutase - - - - - - - - - - - - Hydrolase_3,PMM GGPLMPOG_00825 1680.BADO_0706 6.14e-93 272.0 COG3824@1|root,COG3824@2|Bacteria,2IS6W@201174|Actinobacteria,4D0YK@85004|Bifidobacteriales 201174|Actinobacteria S Zincin-like metallopeptidase - - - - - - - - - - - - Zincin_1 GGPLMPOG_00826 547043.BIFPSEUDO_03463 1.26e-288 795.0 2DNQG@1|root,32YJZ@2|Bacteria,2I2FY@201174|Actinobacteria,4CZE9@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_00827 547043.BIFPSEUDO_03462 0.0 1962.0 COG1216@1|root,COG5617@1|root,COG1216@2|Bacteria,COG5617@2|Bacteria,2I2FX@201174|Actinobacteria,4CYVM@85004|Bifidobacteriales 201174|Actinobacteria S Glycosyl transferase, family 2 - - - - - - - - - - - - Glyco_tranf_2_3,Glyco_trans_2_3 GGPLMPOG_00828 547043.BIFPSEUDO_03461 5.69e-72 215.0 2CC1Y@1|root,32RUK@2|Bacteria,2IQ4Q@201174|Actinobacteria,4D12I@85004|Bifidobacteriales 201174|Actinobacteria K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA whiB2 - - ko:K18955 - - - - ko00000,ko03000 - - - Whib GGPLMPOG_00829 547043.BIFPSEUDO_03460 8.33e-300 822.0 COG1316@1|root,COG1316@2|Bacteria,2GJM3@201174|Actinobacteria,4CZ5B@85004|Bifidobacteriales 201174|Actinobacteria K Cell envelope-related transcriptional attenuator domain yvhJ - - - - - - - - - - - LytR_C,LytR_cpsA_psr GGPLMPOG_00831 547043.BIFPSEUDO_03458 1.37e-218 603.0 COG1316@1|root,COG1316@2|Bacteria,2GJJJ@201174|Actinobacteria,4CYQY@85004|Bifidobacteriales 201174|Actinobacteria K Cell envelope-related transcriptional attenuator domain lytR2 - - - - - - - - - - - LytR_cpsA_psr GGPLMPOG_00832 547043.BIFPSEUDO_03457 0.0 1179.0 COG1674@1|root,COG1674@2|Bacteria,2GJBR@201174|Actinobacteria,4CYU3@85004|Bifidobacteriales 201174|Actinobacteria D FtsK/SpoIIIE family - - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_SpoIIIE,Yop-YscD_cpl GGPLMPOG_00833 1437610.BREU_1071 3.32e-61 187.0 2DMIE@1|root,32RSG@2|Bacteria,2IQCG@201174|Actinobacteria,4D11W@85004|Bifidobacteriales 201174|Actinobacteria K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA whiB GO:0000302,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0010035,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0015035,GO:0015036,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042221,GO:0042493,GO:0045892,GO:0045934,GO:0047134,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0060255,GO:0065007,GO:0071731,GO:0080090,GO:0097159,GO:0097366,GO:1901363,GO:1901698,GO:1901700,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K18955 - - - - ko00000,ko03000 - - - Whib GGPLMPOG_00834 547043.BIFPSEUDO_03455 0.0 957.0 COG3920@1|root,COG3920@2|Bacteria,2GKMP@201174|Actinobacteria,4CYV1@85004|Bifidobacteriales 201174|Actinobacteria T ATPase histidine kinase DNA gyrase B HSP90 domain protein pdtaS GO:0000155,GO:0000160,GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005524,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.13.3 ko:K00936 - M00839 - - ko00000,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,H_kinase_N,HisKA_2,PAS_4 GGPLMPOG_00835 547043.BIFPSEUDO_03454 1.34e-200 556.0 COG1272@1|root,COG1272@2|Bacteria,2GJGQ@201174|Actinobacteria,4CZGT@85004|Bifidobacteriales 201174|Actinobacteria S Haemolysin-III related hlyIII - - ko:K11068 - - - - ko00000,ko02042 - - - HlyIII GGPLMPOG_00836 547043.BIFPSEUDO_03453 2.04e-105 305.0 COG0782@1|root,COG0782@2|Bacteria,2GNZV@201174|Actinobacteria,4D0QM@85004|Bifidobacteriales 201174|Actinobacteria K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides greA GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0071944 - ko:K03624 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N GGPLMPOG_00837 566552.BIFCAT_01064 1.12e-95 278.0 COG0545@1|root,COG0545@2|Bacteria,2GJK2@201174|Actinobacteria,4D0V6@85004|Bifidobacteriales 201174|Actinobacteria G Peptidyl-prolyl cis-trans fkbP - 5.2.1.8 ko:K01802 - - - - ko00000,ko01000 - - - FKBP_C GGPLMPOG_00838 547043.BIFPSEUDO_03451 0.0 977.0 COG1760@1|root,COG1760@2|Bacteria,2GJPA@201174|Actinobacteria,4CZ6I@85004|Bifidobacteriales 201174|Actinobacteria E Serine dehydratase alpha chain sdaA GO:0003674,GO:0003824,GO:0003941,GO:0016829,GO:0016840,GO:0016841 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - SDH_alpha,SDH_beta GGPLMPOG_00839 547043.BIFPSEUDO_03450 9.11e-120 343.0 2ASIR@1|root,31HZA@2|Bacteria,2IHD9@201174|Actinobacteria,4D0QP@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_00841 547043.BIFPSEUDO_03448 4.49e-233 642.0 COG0248@1|root,COG0248@2|Bacteria,2GJBN@201174|Actinobacteria,4CZCS@85004|Bifidobacteriales 201174|Actinobacteria FP Ppx/GppA phosphatase family ppx - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - Ppx-GppA GGPLMPOG_00842 547043.BIFPSEUDO_03447 1.37e-133 378.0 COG1507@1|root,COG1507@2|Bacteria,2I8CS@201174|Actinobacteria,4CZQX@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF501) - - - ko:K09009 - - - - ko00000 - - - DUF501 GGPLMPOG_00843 547043.BIFPSEUDO_03446 4.86e-97 286.0 COG2919@1|root,COG2919@2|Bacteria,2IR5G@201174|Actinobacteria,4D0SS@85004|Bifidobacteriales 201174|Actinobacteria D Septum formation initiator - - - - - - - - - - - - DivIC GGPLMPOG_00844 547043.BIFPSEUDO_03445 7.13e-313 852.0 COG0148@1|root,COG0148@2|Bacteria,2GJAY@201174|Actinobacteria,4CYT3@85004|Bifidobacteriales 201174|Actinobacteria G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno - 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N GGPLMPOG_00845 547043.BIFPSEUDO_03444 0.0 2311.0 COG1197@1|root,COG1197@2|Bacteria,2GJ42@201174|Actinobacteria,4CZ8X@85004|Bifidobacteriales 201174|Actinobacteria L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF GGPLMPOG_00846 547043.BIFPSEUDO_03443 1.42e-145 409.0 COG0193@1|root,COG0193@2|Bacteria,2GKCV@201174|Actinobacteria,4CZBE@85004|Bifidobacteriales 201174|Actinobacteria J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis pth GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro GGPLMPOG_00847 547043.BIFPSEUDO_03442 1.1e-130 370.0 COG1247@1|root,COG1247@2|Bacteria,2HZCB@201174|Actinobacteria,4CZQI@85004|Bifidobacteriales 201174|Actinobacteria M Acetyltransferase (GNAT) domain - - 2.3.1.183 ko:K03823 ko00440,ko01130,map00440,map01130 - R08871,R08938 RC00004,RC00064 ko00000,ko00001,ko01000 - - - Acetyltransf_1,Acetyltransf_3,Acetyltransf_4 GGPLMPOG_00848 547043.BIFPSEUDO_03441 0.0 2023.0 COG1615@1|root,COG1615@2|Bacteria,2GMP3@201174|Actinobacteria,4CYW1@85004|Bifidobacteriales 201174|Actinobacteria S Uncharacterised protein family (UPF0182) - GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - ko:K09118 - - - - ko00000 - - - UPF0182 GGPLMPOG_00849 547043.BIFPSEUDO_03440 7.03e-231 641.0 COG1472@1|root,COG1472@2|Bacteria,2GM43@201174|Actinobacteria,4CZ6R@85004|Bifidobacteriales 201174|Actinobacteria G Glycosyl hydrolase family 3 N-terminal domain protein - - 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 - - - Glyco_hydro_3 GGPLMPOG_00850 547043.BIFPSEUDO_03439 1.2e-53 167.0 COG2879@1|root,COG2879@2|Bacteria,2GQWY@201174|Actinobacteria,4D1IG@85004|Bifidobacteriales 201174|Actinobacteria S Selenoprotein, putative - - - - - - - - - - - - Sel_put GGPLMPOG_00851 547043.BIFPSEUDO_03438 0.0 1506.0 COG1966@1|root,COG1966@2|Bacteria,2GIYX@201174|Actinobacteria,4CZWH@85004|Bifidobacteriales 201174|Actinobacteria T 5TM C-terminal transporter carbon starvation CstA cstA - - ko:K06200 - - - - ko00000 - - - CstA,CstA_5TM GGPLMPOG_00852 547043.BIFPSEUDO_03437 1.32e-69 210.0 COG1687@1|root,COG1687@2|Bacteria,2HZNQ@201174|Actinobacteria,4D12M@85004|Bifidobacteriales 201174|Actinobacteria E Branched-chain amino acid transport protein (AzlD) azlD - - - - - - - - - - - AzlD GGPLMPOG_00853 547043.BIFPSEUDO_03436 7.96e-183 509.0 COG1296@1|root,COG1296@2|Bacteria,2HZA0@201174|Actinobacteria,4CZ7Q@85004|Bifidobacteriales 201174|Actinobacteria E AzlC protein - - - - - - - - - - - - AzlC GGPLMPOG_00854 547043.BIFPSEUDO_03435 4.27e-135 390.0 COG5434@1|root,COG5434@2|Bacteria,2GN7I@201174|Actinobacteria,4CZ0M@85004|Bifidobacteriales 201174|Actinobacteria M Protein of unknown function (DUF3737) - - - - - - - - - - - - DUF3737 GGPLMPOG_00855 547043.BIFPSEUDO_03434 3.99e-106 306.0 COG1490@1|root,COG1490@2|Bacteria,2IKVR@201174|Actinobacteria,4D0VE@85004|Bifidobacteriales 201174|Actinobacteria J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality dtd GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - ko:K07560 - - - - ko00000,ko01000,ko03016 - - - Tyr_Deacylase GGPLMPOG_00856 547043.BIFPSEUDO_03433 0.0 1071.0 COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4D0BX@85004|Bifidobacteriales 201174|Actinobacteria EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 GGPLMPOG_00857 547043.BIFPSEUDO_03432 3.51e-188 523.0 COG0363@1|root,COG0363@2|Bacteria,2GMQ2@201174|Actinobacteria,4CZRG@85004|Bifidobacteriales 201174|Actinobacteria G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase pgl GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31 ko:K01057 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 - - - Glucosamine_iso GGPLMPOG_00858 547043.BIFPSEUDO_03431 5.43e-233 640.0 COG3429@1|root,COG3429@2|Bacteria,2GJ1H@201174|Actinobacteria,4CZI4@85004|Bifidobacteriales 201174|Actinobacteria G Glucose-6-phosphate dehydrogenase subunit opcA - - - - - - - - - - - OpcA_G6PD_assem GGPLMPOG_00859 401473.BDP_0850 0.0 1035.0 COG0364@1|root,COG0364@2|Bacteria,2GISI@201174|Actinobacteria,4CYQM@85004|Bifidobacteriales 201174|Actinobacteria G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone zwf - 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 - - - G6PD_C,G6PD_N GGPLMPOG_00860 547043.BIFPSEUDO_03429 7.34e-270 739.0 COG1168@1|root,COG1168@2|Bacteria,2GJFQ@201174|Actinobacteria,4CZFH@85004|Bifidobacteriales 201174|Actinobacteria E Aminotransferase, class I II - - 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 GGPLMPOG_00861 547043.BIFPSEUDO_03427 7.18e-190 527.0 COG0300@1|root,COG0300@2|Bacteria,2GKJE@201174|Actinobacteria,4CZUC@85004|Bifidobacteriales 201174|Actinobacteria S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - ko:K07124 - - - - ko00000 - - - adh_short GGPLMPOG_00862 547043.BIFPSEUDO_03426 0.0 958.0 COG0362@1|root,COG0362@2|Bacteria,2GJ2J@201174|Actinobacteria,4CZFG@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH gnd - 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 - - - 6PGD,NAD_binding_2 GGPLMPOG_00863 547043.BIFPSEUDO_03425 0.0 1628.0 COG2898@1|root,COG2898@2|Bacteria,2GM2C@201174|Actinobacteria,4CYW5@85004|Bifidobacteriales 201174|Actinobacteria S Uncharacterised conserved protein (DUF2156) lysX - - - - - - - - - - - DUF2156,Rhomboid GGPLMPOG_00864 566552.BIFCAT_01100 6.77e-306 837.0 COG0627@1|root,COG0627@2|Bacteria,2GP6Q@201174|Actinobacteria,4CYXF@85004|Bifidobacteriales 201174|Actinobacteria S Putative esterase - - - - - - - - - - - - Esterase GGPLMPOG_00865 566552.BIFCAT_01102 1.73e-183 512.0 COG1136@1|root,COG1136@2|Bacteria,2I8QP@201174|Actinobacteria,4CZZG@85004|Bifidobacteriales 201174|Actinobacteria V ATPases associated with a variety of cellular activities - - - ko:K02068 - M00211 - - ko00000,ko00002,ko02000 - - - ABC_tran GGPLMPOG_00866 566552.BIFCAT_01103 3.34e-173 484.0 COG0390@1|root,COG0390@2|Bacteria,2GMHX@201174|Actinobacteria,4CYRQ@85004|Bifidobacteriales 201174|Actinobacteria V Uncharacterised protein family (UPF0014) - - - ko:K02069 - M00211 - - ko00000,ko00002,ko02000 9.B.25.1 - - UPF0014 GGPLMPOG_00867 547043.BIFPSEUDO_03418 0.0 1147.0 COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,4CZ4K@85004|Bifidobacteriales 201174|Actinobacteria JKL helicase superfamily c-terminal domain - - - - - - - - - - - - DEAD,Helicase_C GGPLMPOG_00868 547043.BIFPSEUDO_03417 3.13e-163 457.0 COG4221@1|root,COG4221@2|Bacteria,2GMGQ@201174|Actinobacteria,4CZA7@85004|Bifidobacteriales 201174|Actinobacteria S Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short GGPLMPOG_00869 547043.BIFPSEUDO_03415 3.36e-289 792.0 COG2233@1|root,COG2233@2|Bacteria,2GMH6@201174|Actinobacteria,4CZR8@85004|Bifidobacteriales 201174|Actinobacteria F Permease family rutG - - ko:K02824,ko:K03458 - - - - ko00000,ko02000 2.A.40,2.A.40.1.1,2.A.40.1.2 - - Xan_ur_permease GGPLMPOG_00870 547043.BIFPSEUDO_03414 5.52e-201 555.0 COG0406@1|root,COG0406@2|Bacteria,2GN7B@201174|Actinobacteria,4CZFM@85004|Bifidobacteriales 201174|Actinobacteria G Phosphoglycerate mutase family - - - - - - - - - - - - His_Phos_1 GGPLMPOG_00871 547043.BIFPSEUDO_03412 3.4e-175 488.0 COG2207@1|root,COG2207@2|Bacteria,2I2FW@201174|Actinobacteria,4CYW3@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - AraC_binding,HTH_18 GGPLMPOG_00872 547043.BIFPSEUDO_04448 1.12e-184 515.0 COG0730@1|root,COG0730@2|Bacteria,2GJCC@201174|Actinobacteria,4CZ65@85004|Bifidobacteriales 201174|Actinobacteria S Sulfite exporter TauE/SafE - - - ko:K07090 - - - - ko00000 - - - TauE GGPLMPOG_00873 566552.BIFCAT_01932 4.4e-104 304.0 298ZI@1|root,2ZW3A@2|Bacteria,2GP6V@201174|Actinobacteria,4D056@85004|Bifidobacteriales 201174|Actinobacteria S ECF transporter, substrate-specific component - - - - - - - - - - - - - GGPLMPOG_00874 1680.BADO_0650 5.87e-104 305.0 COG0572@1|root,COG0572@2|Bacteria,2HZFA@201174|Actinobacteria,4D08J@85004|Bifidobacteriales 201174|Actinobacteria F uridine kinase - - - - - - - - - - - - - GGPLMPOG_00875 547043.BIFPSEUDO_04445 3.52e-201 559.0 COG2768@1|root,COG2768@2|Bacteria,2IBJZ@201174|Actinobacteria,4CZFQ@85004|Bifidobacteriales 201174|Actinobacteria C Domain of unknown function (DUF362) - - - ko:K07138 - - - - ko00000 - - - DUF362 GGPLMPOG_00876 566552.BIFCAT_01929 2.07e-235 657.0 COG1757@1|root,COG1757@2|Bacteria,2I8CQ@201174|Actinobacteria,4CZ4U@85004|Bifidobacteriales 201174|Actinobacteria C Na H antiporter family protein nhaC - - ko:K03315 - - - - ko00000,ko02000 2.A.35 - - Na_H_antiporter GGPLMPOG_00877 401473.BDP_0827 1.44e-220 612.0 COG2855@1|root,COG2855@2|Bacteria,2GS6E@201174|Actinobacteria,4CZWB@85004|Bifidobacteriales 201174|Actinobacteria S Conserved hypothetical protein 698 - - - - - - - - - - - - Cons_hypoth698 GGPLMPOG_00878 566552.BIFCAT_01926 7.27e-129 373.0 2AUIM@1|root,31K74@2|Bacteria,2IKCM@201174|Actinobacteria,4D0UW@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_00879 1680.BADO_0645 1.09e-103 320.0 COG0370@1|root,COG0370@2|Bacteria,2GTV2@201174|Actinobacteria,4CZRU@85004|Bifidobacteriales 201174|Actinobacteria P transporter of a GTP-driven Fe(2 ) uptake system feoB - - ko:K04759 - - - - ko00000,ko02000 9.A.8.1 - - FeoA,FeoB_C,FeoB_N,Gate GGPLMPOG_00880 566552.BIFCAT_01925 0.0 1232.0 COG0477@1|root,COG0517@1|root,COG0517@2|Bacteria,COG2814@2|Bacteria,2GIZX@201174|Actinobacteria,4CZWX@85004|Bifidobacteriales 201174|Actinobacteria U Drug resistance MFS transporter, drug H antiporter-2 family - - - - - - - - - - - - CBS,MFS_1 GGPLMPOG_00881 547043.BIFPSEUDO_04438 2.7e-17 73.6 29G83@1|root,3035W@2|Bacteria,2GQWW@201174|Actinobacteria,4D1G9@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_00882 518635.BIFANG_03047 6.19e-24 93.2 COG3304@1|root,COG3304@2|Bacteria,2IKS5@201174|Actinobacteria,4D11K@85004|Bifidobacteriales 201174|Actinobacteria S Inner membrane component domain yccF - - - - - - - - - - - YccF GGPLMPOG_00883 547043.BIFPSEUDO_04436 3.03e-257 706.0 COG0012@1|root,COG0012@2|Bacteria,2GIXI@201174|Actinobacteria,4CZBU@85004|Bifidobacteriales 201174|Actinobacteria J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner ychF - - ko:K06942 - - - - ko00000,ko03009 - - - MMR_HSR1,YchF-GTPase_C GGPLMPOG_00884 566552.BIFCAT_01921 2.02e-176 493.0 COG0345@1|root,COG0345@2|Bacteria,2GJ7D@201174|Actinobacteria,4CZIV@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC - 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - - F420_oxidored,P5CR_dimer GGPLMPOG_00885 547043.BIFPSEUDO_04434 0.0 903.0 COG0596@1|root,COG0596@2|Bacteria,2GK03@201174|Actinobacteria,4CZ9T@85004|Bifidobacteriales 201174|Actinobacteria S alpha/beta hydrolase fold pip - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 GGPLMPOG_00886 547043.BIFPSEUDO_04433 0.0 1649.0 COG4585@1|root,COG4585@2|Bacteria,2GJEG@201174|Actinobacteria,4CZ1M@85004|Bifidobacteriales 201174|Actinobacteria T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA_3 GGPLMPOG_00887 547043.BIFPSEUDO_04432 1.74e-168 471.0 COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4CYQW@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg GGPLMPOG_00888 547043.BIFPSEUDO_04431 0.0 1585.0 COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,2GJTZ@201174|Actinobacteria,4CZUR@85004|Bifidobacteriales 201174|Actinobacteria MV MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD GGPLMPOG_00889 78345.BMERY_0924 2.47e-180 503.0 COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4CZ04@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter, ATP-binding protein - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran GGPLMPOG_00890 547043.BIFPSEUDO_04429 9.87e-245 672.0 COG1522@1|root,COG1522@2|Bacteria,2GP1P@201174|Actinobacteria,4CZ0V@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn_helix ASNC type asnC - - ko:K03718 - - - - ko00000,ko03000 - - - AsnC_trans_reg,HTH_AsnC-type GGPLMPOG_00891 566552.BIFCAT_01913 2.71e-193 536.0 COG0619@1|root,COG0619@2|Bacteria,2GM93@201174|Actinobacteria,4CZXW@85004|Bifidobacteriales 201174|Actinobacteria P Cobalt transport protein cbiQ - - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - CbiQ GGPLMPOG_00892 547043.BIFPSEUDO_04427 0.0 1039.0 COG1123@1|root,COG4172@2|Bacteria,2H2BQ@201174|Actinobacteria,4CZBA@85004|Bifidobacteriales 201174|Actinobacteria P AAA domain, putative AbiEii toxin, Type IV TA system ykoD - - ko:K16784,ko:K16786,ko:K16787 ko02010,map02010 M00581,M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran GGPLMPOG_00893 547043.BIFPSEUDO_04426 1.88e-124 355.0 COG4720@1|root,COG4720@2|Bacteria,2ICFG@201174|Actinobacteria,4CZMV@85004|Bifidobacteriales 201174|Actinobacteria S ECF-type riboflavin transporter, S component - - - - - - - - - - - - ECF-ribofla_trS GGPLMPOG_00894 566552.BIFCAT_01909 0.0 863.0 COG2873@1|root,COG2873@2|Bacteria,2I2EB@201174|Actinobacteria,4CZCT@85004|Bifidobacteriales 201174|Actinobacteria E Aminotransferase class-V - - 2.5.1.49 ko:K01740 ko00270,ko01100,map00270,map01100 - R01287,R04859 RC00020,RC02821,RC02848 ko00000,ko00001,ko01000 - - - Cys_Met_Meta_PP GGPLMPOG_00895 566552.BIFCAT_01907 8.52e-211 582.0 COG2240@1|root,COG2240@2|Bacteria,2HS59@201174|Actinobacteria,4CYQC@85004|Bifidobacteriales 201174|Actinobacteria H Phosphomethylpyrimidine kinase pdxY - 2.7.1.35 ko:K00868 ko00750,ko01100,map00750,map01100 - R00174,R01909,R02493 RC00002,RC00017 ko00000,ko00001,ko01000 - - - Phos_pyr_kin GGPLMPOG_00896 547043.BIFPSEUDO_04422 4.04e-103 298.0 COG0792@1|root,COG0792@2|Bacteria,2IQ3X@201174|Actinobacteria,4D191@85004|Bifidobacteriales 201174|Actinobacteria L Belongs to the UPF0102 family yraN - - ko:K07460 - - - - ko00000 - - - UPF0102 GGPLMPOG_00897 566552.BIFCAT_01904 0.0 993.0 COG0606@1|root,COG0606@2|Bacteria,2GJIQ@201174|Actinobacteria,4CYUB@85004|Bifidobacteriales 201174|Actinobacteria O Magnesium chelatase, subunit ChlI C-terminal comM GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C GGPLMPOG_00898 566552.BIFCAT_01903 0.0 890.0 COG0758@1|root,COG0758@2|Bacteria,2GKDA@201174|Actinobacteria,4CYVW@85004|Bifidobacteriales 201174|Actinobacteria LU DNA recombination-mediator protein A dprA - - ko:K04096 - - - - ko00000 - - - DNA_processg_A GGPLMPOG_00899 566552.BIFCAT_01902 0.0 1204.0 COG1053@1|root,COG1053@2|Bacteria,2GJ45@201174|Actinobacteria,4CYT5@85004|Bifidobacteriales 201174|Actinobacteria C Succinate dehydrogenase flavoprotein subunit sdhA GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363 1.3.5.1,1.3.5.4,1.4.3.16 ko:K00239,ko:K00278 ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00115,M00149,M00173,M00374,M00376 R00357,R00481,R02164 RC00006,RC00045,RC02566 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C GGPLMPOG_00900 566552.BIFCAT_01901 7.11e-225 619.0 COG0479@1|root,COG0479@2|Bacteria,2GP9C@201174|Actinobacteria,4CZWJ@85004|Bifidobacteriales 201174|Actinobacteria C 4Fe-4S dicluster domain sdhB - 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - Fer2_3,Fer4_10,Fer4_8 GGPLMPOG_00901 566552.BIFCAT_01900 3.38e-149 421.0 COG4122@1|root,COG4122@2|Bacteria,2HXV7@201174|Actinobacteria,4CZZN@85004|Bifidobacteriales 201174|Actinobacteria S O-methyltransferase safC - - - - - - - - - - - Methyltransf_3 GGPLMPOG_00902 566552.BIFCAT_01899 4.03e-307 840.0 COG3004@1|root,COG3004@2|Bacteria,2GKIK@201174|Actinobacteria,4CZES@85004|Bifidobacteriales 201174|Actinobacteria P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons nhaA - - ko:K03313 - - - - ko00000,ko02000 2.A.33.1 - - Na_H_antiport_1 GGPLMPOG_00904 566552.BIFCAT_01896 7.5e-304 830.0 COG1219@1|root,COG1219@2|Bacteria,2GJXQ@201174|Actinobacteria,4CYT6@85004|Bifidobacteriales 201174|Actinobacteria O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP clpX GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030312,GO:0030554,GO:0031333,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0044087,GO:0044238,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - ko:K03544 ko04112,map04112 - - - ko00000,ko00001,ko03110 - - - AAA_2,ClpB_D2-small,zf-C4_ClpX GGPLMPOG_00905 566552.BIFCAT_01895 1.33e-160 450.0 COG0740@1|root,COG0740@2|Bacteria,2GKNK@201174|Actinobacteria,4CZVF@85004|Bifidobacteriales 201174|Actinobacteria O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins clpP GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease GGPLMPOG_00906 1435051.BMOU_2043 3.59e-147 414.0 COG0740@1|root,COG0740@2|Bacteria,2GK5C@201174|Actinobacteria,4CYUU@85004|Bifidobacteriales 201174|Actinobacteria O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins clpP1 - 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease GGPLMPOG_00907 547043.BIFPSEUDO_04408 0.0 1082.0 COG4166@1|root,COG4166@2|Bacteria,2GIUH@201174|Actinobacteria,4CZFK@85004|Bifidobacteriales 201174|Actinobacteria E ABC transporter, substrate-binding protein, family 5 dppA - - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 GGPLMPOG_00908 566552.BIFCAT_01892 0.0 898.0 COG0477@1|root,COG2814@2|Bacteria,2GIZX@201174|Actinobacteria,4CZ0R@85004|Bifidobacteriales 201174|Actinobacteria EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,Sugar_tr GGPLMPOG_00909 566552.BIFCAT_01891 0.0 874.0 COG2256@1|root,COG2256@2|Bacteria,2GKDP@201174|Actinobacteria,4CZ2K@85004|Bifidobacteriales 201174|Actinobacteria L Recombination factor protein RarA rarA - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N GGPLMPOG_00910 547043.BIFPSEUDO_04398 0.0 1701.0 COG4581@1|root,COG4581@2|Bacteria,2GJSV@201174|Actinobacteria,4CZVX@85004|Bifidobacteriales 201174|Actinobacteria L DEAD DEAH box helicase - - - - - - - - - - - - DEAD,DUF3516,Helicase_C GGPLMPOG_00911 547043.BIFPSEUDO_04397 2.85e-243 668.0 COG2326@1|root,COG2326@2|Bacteria,2GKRN@201174|Actinobacteria,4CZZU@85004|Bifidobacteriales 201174|Actinobacteria S Polyphosphate kinase 2 (PPK2) - - - - - - - - - - - - PPK2 GGPLMPOG_00912 547043.BIFPSEUDO_04396 3.03e-258 709.0 COG0765@1|root,COG0765@2|Bacteria,2GNBH@201174|Actinobacteria,4CZB4@85004|Bifidobacteriales 201174|Actinobacteria E Binding-protein-dependent transport system inner membrane component gluD - - ko:K10007 ko02010,map02010 M00233 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.9 - - BPD_transp_1 GGPLMPOG_00913 547043.BIFPSEUDO_04395 1.04e-144 409.0 COG0765@1|root,COG0765@2|Bacteria,2GNUR@201174|Actinobacteria,4CZ5M@85004|Bifidobacteriales 201174|Actinobacteria E Binding-protein-dependent transport system inner membrane component gluC - - ko:K10006 ko02010,map02010 M00233 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.9 - - BPD_transp_1 GGPLMPOG_00914 547043.BIFPSEUDO_04394 3.59e-196 544.0 COG0834@1|root,COG0834@2|Bacteria,2GJH8@201174|Actinobacteria,4CZA4@85004|Bifidobacteriales 201174|Actinobacteria ET Belongs to the bacterial solute-binding protein 3 family gluB - - ko:K10005 ko02010,map02010 M00233 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.9 - - SBP_bac_3 GGPLMPOG_00915 547043.BIFPSEUDO_04393 1.57e-176 493.0 COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria,4CYXE@85004|Bifidobacteriales 201174|Actinobacteria E ATP-binding protein of ABC transporter for glutamate K02028 gluA - - ko:K10008 ko02010,map02010 M00233 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3.9 - - ABC_tran GGPLMPOG_00916 547043.BIFPSEUDO_04391 1.01e-179 500.0 COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria,4CZ3R@85004|Bifidobacteriales 201174|Actinobacteria E ATPases associated with a variety of cellular activities glnQ - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran GGPLMPOG_00917 547043.BIFPSEUDO_04390 0.0 973.0 COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,2GJJ9@201174|Actinobacteria,4CZIX@85004|Bifidobacteriales 201174|Actinobacteria E Binding-protein-dependent transport system inner membrane component glnP - - ko:K02029,ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1,SBP_bac_3 GGPLMPOG_00918 547043.BIFPSEUDO_04389 0.0 1194.0 COG0173@1|root,COG0173@2|Bacteria,2GJHU@201174|Actinobacteria,4CYWQ@85004|Bifidobacteriales 201174|Actinobacteria J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) aspS GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - GAD,tRNA-synt_2,tRNA_anti-codon GGPLMPOG_00919 1680.BADO_0588 0.0 870.0 COG0124@1|root,COG0124@2|Bacteria,2GIYJ@201174|Actinobacteria,4CYR9@85004|Bifidobacteriales 201174|Actinobacteria J Histidyl-tRNA synthetase hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_His GGPLMPOG_00920 547043.BIFPSEUDO_04386 1.25e-299 824.0 COG3266@1|root,COG3266@2|Bacteria,2I2EC@201174|Actinobacteria,4CYYM@85004|Bifidobacteriales 201174|Actinobacteria S Domain of Unknown Function (DUF349) - - - - - - - - - - - - DUF349 GGPLMPOG_00921 547043.BIFPSEUDO_04385 4.91e-180 501.0 COG1402@1|root,COG1402@2|Bacteria,2HCRK@201174|Actinobacteria,4CZW9@85004|Bifidobacteriales 201174|Actinobacteria S Creatinine amidohydrolase - - 3.5.2.10 ko:K01470 ko00330,map00330 - R01884 RC00615 ko00000,ko00001,ko01000 - - - Creatininase GGPLMPOG_00922 547043.BIFPSEUDO_04384 1.06e-315 862.0 COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria,4CYY8@85004|Bifidobacteriales 201174|Actinobacteria EGP Sugar (and other) transporter proP - - ko:K03762 - - - - ko00000,ko02000 2.A.1.6.4 - - MFS_1,Sugar_tr GGPLMPOG_00923 547043.BIFPSEUDO_04383 0.0 986.0 COG2508@1|root,COG2508@2|Bacteria,2HPPC@201174|Actinobacteria,4D0FM@85004|Bifidobacteriales 201174|Actinobacteria QT Purine catabolism regulatory protein-like family - - - - - - - - - - - - HTH_30,PucR GGPLMPOG_00924 547043.BIFPSEUDO_04382 0.0 878.0 COG0402@1|root,COG0402@2|Bacteria,2GKKM@201174|Actinobacteria,4D07T@85004|Bifidobacteriales 201174|Actinobacteria F Amidohydrolase family codA - 3.5.4.1,3.5.4.21 ko:K01485,ko:K03365 ko00240,ko00330,ko01100,map00240,map00330,map01100 - R00974,R01411,R02922 RC00074,RC00514,RC00809 ko00000,ko00001,ko01000 - - - Amidohydro_3 GGPLMPOG_00925 547043.BIFPSEUDO_04381 0.0 1614.0 COG0542@1|root,COG0542@2|Bacteria,2GJ77@201174|Actinobacteria,4CZCH@85004|Bifidobacteriales 201174|Actinobacteria O ATPase family associated with various cellular activities (AAA) clpC GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944 - ko:K03696 ko01100,map01100 - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N,UVR GGPLMPOG_00926 547043.BIFPSEUDO_04380 1.12e-241 664.0 COG0589@1|root,COG0589@2|Bacteria,2IA7S@201174|Actinobacteria,4CZZ0@85004|Bifidobacteriales 201174|Actinobacteria T Belongs to the universal stress protein A family uspA - - - - - - - - - - - Usp GGPLMPOG_00927 547043.BIFPSEUDO_04379 4.98e-243 672.0 28NWB@1|root,2ZBU7@2|Bacteria,2GJ74@201174|Actinobacteria,4CYW9@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF3027) - - - - - - - - - - - - DUF3027 GGPLMPOG_00928 547043.BIFPSEUDO_04378 6.1e-88 258.0 COG1278@1|root,COG1278@2|Bacteria,2IKXN@201174|Actinobacteria,4D0V4@85004|Bifidobacteriales 201174|Actinobacteria K 'Cold-shock' DNA-binding domain cspB - - ko:K03704 - - - - ko00000,ko03000 - - - CSD GGPLMPOG_00929 547043.BIFPSEUDO_04377 0.0 1169.0 COG3850@1|root,COG5002@1|root,COG3850@2|Bacteria,COG5002@2|Bacteria,2I2DU@201174|Actinobacteria,4CZNF@85004|Bifidobacteriales 201174|Actinobacteria T ATPase histidine kinase DNA gyrase B HSP90 domain protein phoR - 2.7.13.3 ko:K02484 - - - - ko00000,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA GGPLMPOG_00930 547043.BIFPSEUDO_04376 3.53e-170 475.0 COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4CYPS@85004|Bifidobacteriales 201174|Actinobacteria KT Response regulator receiver domain protein phoP - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C GGPLMPOG_00931 547043.BIFPSEUDO_04374 8.75e-169 474.0 2B59T@1|root,31Y3Y@2|Bacteria,2HZNR@201174|Actinobacteria,4D12Q@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - TPM_phosphatase GGPLMPOG_00932 547043.BIFPSEUDO_04375 1.74e-38 133.0 COG4842@1|root,COG4842@2|Bacteria,2GQI8@201174|Actinobacteria,4D17K@85004|Bifidobacteriales 201174|Actinobacteria S Proteins of 100 residues with WXG - - - - - - - - - - - - WXG100 GGPLMPOG_00933 547043.BIFPSEUDO_04372 0.0 1002.0 COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria,4CZJK@85004|Bifidobacteriales 201174|Actinobacteria O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016020,GO:0016465,GO:0022610,GO:0030112,GO:0030312,GO:0030313,GO:0031975,GO:0032991,GO:0036293,GO:0040007,GO:0042026,GO:0042603,GO:0043388,GO:0044093,GO:0044183,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051082,GO:0051098,GO:0051099,GO:0051101,GO:0051704,GO:0061077,GO:0065007,GO:0065009,GO:0070482,GO:0071944,GO:0101031,GO:1990220,GO:2000677,GO:2000679 - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 GGPLMPOG_00934 547043.BIFPSEUDO_02300 4e-116 337.0 2DP6P@1|root,330SA@2|Bacteria,2GQYA@201174|Actinobacteria,4CZYT@85004|Bifidobacteriales 201174|Actinobacteria S LytR cell envelope-related transcriptional attenuator - - - - - - - - - - - - LytR_C GGPLMPOG_00935 547043.BIFPSEUDO_02301 9.46e-176 489.0 COG0692@1|root,COG0692@2|Bacteria,2GJ9Z@201174|Actinobacteria,4CZ3Y@85004|Bifidobacteriales 201174|Actinobacteria L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine ung GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG GGPLMPOG_00936 547043.BIFPSEUDO_02302 1.31e-233 644.0 COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4CZ2I@85004|Bifidobacteriales 201174|Actinobacteria S ATPase family associated with various cellular activities (AAA) moxR - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 GGPLMPOG_00937 547043.BIFPSEUDO_02303 2.12e-224 619.0 COG1721@1|root,COG1721@2|Bacteria,2GKSJ@201174|Actinobacteria,4CYYD@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function DUF58 - - - - - - - - - - - - DUF58 GGPLMPOG_00938 547043.BIFPSEUDO_02304 1.34e-120 344.0 2AUTC@1|root,31KGE@2|Bacteria,2IKRN@201174|Actinobacteria,4D134@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_00939 547043.BIFPSEUDO_02305 5.1e-242 666.0 COG2304@1|root,COG2304@2|Bacteria,2I9VM@201174|Actinobacteria,4CZ00@85004|Bifidobacteriales 201174|Actinobacteria S von Willebrand factor (vWF) type A domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA,VWA_2 GGPLMPOG_00940 547043.BIFPSEUDO_02306 2.79e-231 638.0 COG2304@1|root,COG2304@2|Bacteria,2GJMP@201174|Actinobacteria,4CZ8P@85004|Bifidobacteriales 201174|Actinobacteria S von Willebrand factor (vWF) type A domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA,VWA_2 GGPLMPOG_00941 547043.BIFPSEUDO_02307 7.03e-104 303.0 2BG6D@1|root,32A37@2|Bacteria,2IR67@201174|Actinobacteria,4D18W@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_00942 547043.BIFPSEUDO_02310 0.0 958.0 COG1075@1|root,COG1075@2|Bacteria,2IHFB@201174|Actinobacteria,4CZ17@85004|Bifidobacteriales 201174|Actinobacteria S PGAP1-like protein - - - - - - - - - - - - Abhydrolase_6,Abhydrolase_8,PGAP1 GGPLMPOG_00943 547043.BIFPSEUDO_02311 0.0 962.0 COG0015@1|root,COG0015@2|Bacteria,2GM71@201174|Actinobacteria,4CYV6@85004|Bifidobacteriales 201174|Actinobacteria F Adenylosuccinate lyase C-terminal purB - 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - - ASL_C,Lyase_1 GGPLMPOG_00944 547043.BIFPSEUDO_02312 0.0 1521.0 COG0392@1|root,COG0392@2|Bacteria,2GMAV@201174|Actinobacteria,4CYRT@85004|Bifidobacteriales 201174|Actinobacteria S Lysylphosphatidylglycerol synthase TM region - - - - - - - - - - - - LPG_synthase_TM GGPLMPOG_00945 1435051.BMOU_2003 4.7e-57 177.0 COG0776@1|root,COG0776@2|Bacteria,2IKQR@201174|Actinobacteria,4D11V@85004|Bifidobacteriales 201174|Actinobacteria L Belongs to the bacterial histone-like protein family hup GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141 - ko:K03530 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding GGPLMPOG_00946 547043.BIFPSEUDO_02314 1.11e-77 231.0 2AUT3@1|root,31KG5@2|Bacteria,2IKR4@201174|Actinobacteria,4D141@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_00947 547043.BIFPSEUDO_02315 7.66e-181 504.0 COG1304@1|root,COG1304@2|Bacteria,2HHRH@201174|Actinobacteria,4CZI2@85004|Bifidobacteriales 201174|Actinobacteria C FMN binding - - - - - - - - - - - - - GGPLMPOG_00948 547043.BIFPSEUDO_02316 0.0 966.0 COG0638@1|root,COG0638@2|Bacteria,2GMC6@201174|Actinobacteria,4CZ12@85004|Bifidobacteriales 201174|Actinobacteria O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine pafA GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 6.3.1.19 ko:K13571 - M00342 R11207 RC00090,RC00096 ko00000,ko00002,ko01000,ko03051 - - - Pup_ligase GGPLMPOG_00949 547043.BIFPSEUDO_02317 5.14e-34 117.0 2B5FT@1|root,31YAF@2|Bacteria,2GV5R@201174|Actinobacteria,4D1NH@85004|Bifidobacteriales 201174|Actinobacteria S Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation pup - - ko:K13570 - - - - ko00000,ko04121 - - - Pup GGPLMPOG_00950 547043.BIFPSEUDO_02318 8.18e-206 568.0 COG0483@1|root,COG0483@2|Bacteria,2HGP2@201174|Actinobacteria,4CYWZ@85004|Bifidobacteriales 201174|Actinobacteria G Inositol monophosphatase family - - 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P GGPLMPOG_00951 547043.BIFPSEUDO_02319 0.0 1041.0 COG4122@1|root,COG4122@2|Bacteria,2GJGI@201174|Actinobacteria,4CZAN@85004|Bifidobacteriales 201174|Actinobacteria S Pup-ligase protein dop GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.5.1.119 ko:K20814 - - - - ko00000,ko01000,ko03051 - - - Pup_ligase GGPLMPOG_00952 547043.BIFPSEUDO_02320 0.0 982.0 COG1222@1|root,COG1222@2|Bacteria,2GMR1@201174|Actinobacteria,4CZ86@85004|Bifidobacteriales 201174|Actinobacteria O AAA ATPase forming ring-shaped complexes arc GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369 - ko:K13527 ko03050,map03050 M00342 - - ko00000,ko00001,ko00002,ko03051 - - - AAA,Prot_ATP_ID_OB GGPLMPOG_00953 547043.BIFPSEUDO_02321 4.49e-159 446.0 COG0560@1|root,COG0560@2|Bacteria,2GJDH@201174|Actinobacteria,4CYWC@85004|Bifidobacteriales 201174|Actinobacteria E haloacid dehalogenase-like hydrolase serB - 3.1.3.3 ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R00582 RC00017 ko00000,ko00001,ko00002,ko01000,ko01009 - - - HAD GGPLMPOG_00954 547043.BIFPSEUDO_02322 3.54e-229 631.0 COG0223@1|root,COG0223@2|Bacteria,2GKH5@201174|Actinobacteria,4CZ8C@85004|Bifidobacteriales 201174|Actinobacteria J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0040007,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - - Formyl_trans_C,Formyl_trans_N GGPLMPOG_00955 547043.BIFPSEUDO_02323 1.23e-172 481.0 COG1011@1|root,COG1011@2|Bacteria,2I8XE@201174|Actinobacteria,4CZGV@85004|Bifidobacteriales 201174|Actinobacteria S Haloacid dehalogenase-like hydrolase - - 3.8.1.2 ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - HAD_2 GGPLMPOG_00956 547043.BIFPSEUDO_02324 0.0 1463.0 COG1198@1|root,COG1198@2|Bacteria,2GKES@201174|Actinobacteria,4D04J@85004|Bifidobacteriales 201174|Actinobacteria L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - - GGPLMPOG_00957 547043.BIFPSEUDO_02325 7.42e-291 795.0 COG0192@1|root,COG0192@2|Bacteria,2GJ4U@201174|Actinobacteria,4CZ5D@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme metK GO:0003674,GO:0003824,GO:0004478,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0016740,GO:0016765,GO:0019899,GO:0030312,GO:0035375,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - - S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N GGPLMPOG_00958 547043.BIFPSEUDO_02326 5.45e-61 187.0 COG1758@1|root,COG1758@2|Bacteria,2IQHU@201174|Actinobacteria,4D12C@85004|Bifidobacteriales 201174|Actinobacteria K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits rpoZ GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb6 GGPLMPOG_00959 547043.BIFPSEUDO_02327 0.0 1237.0 COG0129@1|root,COG0129@2|Bacteria,2GJIJ@201174|Actinobacteria,4CZ1T@85004|Bifidobacteriales 201174|Actinobacteria H Belongs to the IlvD Edd family ilvD - 4.2.1.9 ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000 - - - ILVD_EDD GGPLMPOG_00961 547043.BIFPSEUDO_02330 3.1e-138 390.0 COG0194@1|root,COG0194@2|Bacteria,2I2FT@201174|Actinobacteria,4CYUT@85004|Bifidobacteriales 201174|Actinobacteria F Essential for recycling GMP and indirectly, cGMP gmk - 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_kin GGPLMPOG_00962 547043.BIFPSEUDO_02331 1.42e-218 603.0 COG0284@1|root,COG0284@2|Bacteria,2GKWK@201174|Actinobacteria,4D2UX@85004|Bifidobacteriales 201174|Actinobacteria F Essential for recycling GMP and indirectly, cGMP pyrF - 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase GGPLMPOG_00963 547043.BIFPSEUDO_02332 0.0 2206.0 COG0458@1|root,COG0458@2|Bacteria,2GK5N@201174|Actinobacteria,4CZJ4@85004|Bifidobacteriales 201174|Actinobacteria EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain carB - 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS GGPLMPOG_00964 547043.BIFPSEUDO_02333 2.95e-305 830.0 COG0505@1|root,COG0505@2|Bacteria,2GKFA@201174|Actinobacteria,4CYQ1@85004|Bifidobacteriales 201174|Actinobacteria F Belongs to the CarA family carA GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv1383 CPSase_sm_chain,GATase GGPLMPOG_00965 547043.BIFPSEUDO_02334 1.21e-98 286.0 COG0781@1|root,COG0781@2|Bacteria,2IM3D@201174|Actinobacteria,4D0WG@85004|Bifidobacteriales 201174|Actinobacteria K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons nusB GO:0008150,GO:0040007 - ko:K03625 - - - - ko00000,ko03009,ko03021 - - - NusB GGPLMPOG_00966 547043.BIFPSEUDO_02335 2.2e-134 380.0 COG0231@1|root,COG0231@2|Bacteria,2GJMS@201174|Actinobacteria,4CYY6@85004|Bifidobacteriales 201174|Actinobacteria J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C GGPLMPOG_00967 547043.BIFPSEUDO_02336 2.12e-295 805.0 COG0050@1|root,COG0050@2|Bacteria,2GK4T@201174|Actinobacteria,4CYY7@85004|Bifidobacteriales 201174|Actinobacteria J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis tuf GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0019899,GO:0030312,GO:0035375,GO:0036293,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944 - ko:K02358 - - - - ko00000,ko03012,ko03029,ko04147 - - - GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 GGPLMPOG_00968 547043.BIFPSEUDO_02338 0.0 1405.0 COG0480@1|root,COG0480@2|Bacteria,2GKB3@201174|Actinobacteria,4CYTB@85004|Bifidobacteriales 201174|Actinobacteria J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome fusA GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 GGPLMPOG_00969 1435051.BMOU_1979 9.4e-105 303.0 COG0049@1|root,COG0049@2|Bacteria,2GMVW@201174|Actinobacteria,4CZQJ@85004|Bifidobacteriales 201174|Actinobacteria J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02992 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S7 GGPLMPOG_00970 1435051.BMOU_1978 5.77e-81 240.0 COG0048@1|root,COG0048@2|Bacteria,2IHUF@201174|Actinobacteria,4D0PK@85004|Bifidobacteriales 201174|Actinobacteria J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit rpsL GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02950 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosom_S12_S23 GGPLMPOG_00972 547043.BIFPSEUDO_02342 5.25e-241 663.0 COG0385@1|root,COG0385@2|Bacteria,2GMAM@201174|Actinobacteria,4CZ1K@85004|Bifidobacteriales 201174|Actinobacteria S SBF-like CPA transporter family (DUF4137) - - - ko:K03453 - - - - ko00000 2.A.28 - - SBF GGPLMPOG_00974 547043.BIFPSEUDO_02344 8.99e-254 695.0 COG2008@1|root,COG2008@2|Bacteria,2GJ0V@201174|Actinobacteria,4CZ7G@85004|Bifidobacteriales 201174|Actinobacteria E Beta-eliminating lyase ltaE - 4.1.2.48 ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 - R00751,R06171 RC00312,RC00372 ko00000,ko00001,ko01000 - - - Beta_elim_lyase GGPLMPOG_00975 547043.BIFPSEUDO_02345 2.64e-289 789.0 COG0438@1|root,COG0438@2|Bacteria,2HEH6@201174|Actinobacteria,4CZSN@85004|Bifidobacteriales 201174|Actinobacteria M Glycosyl transferase 4-like domain - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 GGPLMPOG_00976 547043.BIFPSEUDO_02346 1.21e-288 790.0 COG0027@1|root,COG0027@2|Bacteria,2GMCS@201174|Actinobacteria,4CZXH@85004|Bifidobacteriales 201174|Actinobacteria F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate purT GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008776,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0044237,GO:0044424,GO:0044444,GO:0044464 2.1.2.2 ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv0389 ATP-grasp,Epimerase GGPLMPOG_00977 547043.BIFPSEUDO_02347 1.97e-175 489.0 COG0152@1|root,COG0152@2|Bacteria,2GK3H@201174|Actinobacteria,4CZGQ@85004|Bifidobacteriales 201174|Actinobacteria F Belongs to the SAICAR synthetase family purC - 6.3.2.6 ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04591 RC00064,RC00162 ko00000,ko00001,ko00002,ko01000 - - - SAICAR_synt GGPLMPOG_00978 547043.BIFPSEUDO_02348 0.0 2445.0 COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,2GKG6@201174|Actinobacteria,4CZ7C@85004|Bifidobacteriales 201174|Actinobacteria F CobB/CobQ-like glutamine amidotransferase domain purL - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C,GATase_5 GGPLMPOG_00979 547043.BIFPSEUDO_02349 1.3e-48 154.0 2DTWH@1|root,33MZC@2|Bacteria,2GUGG@201174|Actinobacteria,4D1FM@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_00980 547043.BIFPSEUDO_02350 0.0 1063.0 COG0389@1|root,COG0389@2|Bacteria,2GQX7@201174|Actinobacteria,4CZ0D@85004|Bifidobacteriales 201174|Actinobacteria L DNA-damage repair protein (DNA polymerase IV) K00961 - - - ko:K03502 - - - - ko00000,ko03400 - - - IMS,IMS_C,IMS_HHH GGPLMPOG_00981 1435051.BMOU_1969 0.0 979.0 COG0034@1|root,COG0034@2|Bacteria,2GK6I@201174|Actinobacteria,4CZ89@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine purF GO:0008150,GO:0040007 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase_6,GATase_7,Pribosyltran GGPLMPOG_00982 547043.BIFPSEUDO_02353 1.07e-242 667.0 COG0150@1|root,COG0150@2|Bacteria,2GJNY@201174|Actinobacteria,4CZ3K@85004|Bifidobacteriales 201174|Actinobacteria F Phosphoribosylformylglycinamidine cyclo-ligase purM GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016874,GO:0016879,GO:0016882,GO:0044424,GO:0044444,GO:0044464 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C GGPLMPOG_00983 547043.BIFPSEUDO_02354 9.82e-298 813.0 COG0151@1|root,COG0151@2|Bacteria,2I2F5@201174|Actinobacteria,4CZ3I@85004|Bifidobacteriales 201174|Actinobacteria F Belongs to the GARS family purD GO:0008150,GO:0040007 6.3.3.1,6.3.4.13 ko:K01945,ko:K11788 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144,R04208 RC00090,RC00166,RC01100 ko00000,ko00001,ko00002,ko01000 - - - GARS_A,GARS_C,GARS_N GGPLMPOG_00984 547043.BIFPSEUDO_02355 7.78e-314 858.0 COG0477@1|root,COG2814@2|Bacteria,2H8UD@201174|Actinobacteria,4CZ16@85004|Bifidobacteriales 201174|Actinobacteria EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,Sugar_tr GGPLMPOG_00985 547043.BIFPSEUDO_02356 8.1e-236 647.0 COG1957@1|root,COG1957@2|Bacteria,2GP6N@201174|Actinobacteria,4CZIN@85004|Bifidobacteriales 201174|Actinobacteria F Inosine-uridine preferring nucleoside hydrolase rihB - 3.2.2.1,3.2.2.8 ko:K01239,ko:K01250,ko:K10213 ko00230,ko00240,ko00760,ko01100,map00230,map00240,map00760,map01100 - R01245,R01273,R01677,R01770,R02137,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 - - - IU_nuc_hydro GGPLMPOG_00986 547043.BIFPSEUDO_02357 2.58e-274 751.0 COG1454@1|root,COG1454@2|Bacteria,2I2FD@201174|Actinobacteria,4D24P@85004|Bifidobacteriales 201174|Actinobacteria C Iron-containing alcohol dehydrogenase - - - ko:K19954 - - - - ko00000,ko01000 - - - Fe-ADH GGPLMPOG_00987 547043.BIFPSEUDO_02358 1.06e-165 463.0 COG0135@1|root,COG0135@2|Bacteria,2IHPP@201174|Actinobacteria,4D17S@85004|Bifidobacteriales 201174|Actinobacteria E N-(5'phosphoribosyl)anthranilate (PRA) isomerase trpF - 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 - - - PRAI GGPLMPOG_00988 547043.BIFPSEUDO_02359 4.55e-242 664.0 COG0524@1|root,COG0524@2|Bacteria,2HZA1@201174|Actinobacteria,4CZ7T@85004|Bifidobacteriales 2|Bacteria G pfkB family carbohydrate kinase yeiI GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050225 2.7.1.15,2.7.1.45,2.7.1.83 ko:K00852,ko:K00874,ko:K16328 ko00030,ko00240,ko01100,ko01120,ko01200,map00030,map00240,map01100,map01120,map01200 M00061,M00308,M00631 R01051,R01541,R02750,R03315 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HTH_24,PfkB GGPLMPOG_00989 547043.BIFPSEUDO_02360 6.65e-259 710.0 COG0524@1|root,COG1522@1|root,COG0524@2|Bacteria,COG1522@2|Bacteria,2HZA1@201174|Actinobacteria,4CZ7T@85004|Bifidobacteriales 201174|Actinobacteria G pfkB family carbohydrate kinase - - 2.7.1.83 ko:K16328 ko00240,map00240 - R03315 RC00002,RC00017 ko00000,ko00001,ko01000 - - - HTH_24,PfkB GGPLMPOG_00990 547043.BIFPSEUDO_02361 0.0 1362.0 COG1368@1|root,COG1368@2|Bacteria,2HVID@201174|Actinobacteria,4CZ6J@85004|Bifidobacteriales 201174|Actinobacteria M Psort location CytoplasmicMembrane, score 9.26 - - - - - - - - - - - - Sulfatase GGPLMPOG_00991 547043.BIFPSEUDO_02362 7.41e-117 333.0 COG0735@1|root,COG0735@2|Bacteria,2IKS3@201174|Actinobacteria,4D0XG@85004|Bifidobacteriales 201174|Actinobacteria P Belongs to the Fur family fur - - ko:K03711 - - - - ko00000,ko03000 - - - FUR GGPLMPOG_00992 547043.BIFPSEUDO_02363 3.33e-287 783.0 COG0026@1|root,COG0026@2|Bacteria,2GJCU@201174|Actinobacteria,4CYWP@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) purK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp GGPLMPOG_00993 547043.BIFPSEUDO_02364 2.09e-110 318.0 COG0041@1|root,COG0041@2|Bacteria,2IFFD@201174|Actinobacteria,4CYQZ@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) purE GO:0008150,GO:0040007 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv3275c AIRC GGPLMPOG_00994 547043.BIFPSEUDO_02365 1.56e-232 640.0 COG0604@1|root,COG0604@2|Bacteria,2GMHR@201174|Actinobacteria,4D00X@85004|Bifidobacteriales 201174|Actinobacteria C Zinc-binding dehydrogenase yogA - - - - - - - - - - - ADH_N,ADH_zinc_N GGPLMPOG_00995 547043.BIFPSEUDO_02366 0.0 1252.0 COG1154@1|root,COG1154@2|Bacteria,2GMFA@201174|Actinobacteria,4CZ2M@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) dxs GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0008661,GO:0009058,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030145,GO:0030975,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901363,GO:1901576,GO:1901681 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - - DXP_synthase_N,Transket_pyr,Transketolase_C GGPLMPOG_00996 566552.BIFCAT_01798 0.0 889.0 COG0577@1|root,COG0577@2|Bacteria,2GIRW@201174|Actinobacteria,4CZMQ@85004|Bifidobacteriales 201174|Actinobacteria V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD GGPLMPOG_00997 547043.BIFPSEUDO_02368 1.89e-207 580.0 COG1361@1|root,COG1361@2|Bacteria,2GP6I@201174|Actinobacteria,4D013@85004|Bifidobacteriales 201174|Actinobacteria M Conserved repeat domain - - - - - - - - - - - - - GGPLMPOG_00998 547043.BIFPSEUDO_02369 2.3e-171 478.0 COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4D2SJ@85004|Bifidobacteriales 201174|Actinobacteria V ATPases associated with a variety of cellular activities - GO:0008150,GO:0009405,GO:0009605,GO:0009607,GO:0043207,GO:0044403,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136 - ko:K02003,ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,FtsX GGPLMPOG_00999 547043.BIFPSEUDO_02370 2.54e-97 284.0 2AU97@1|root,31JWK@2|Bacteria,2IJXF@201174|Actinobacteria,4D0W5@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01000 78345.BMERY_1643 2.8e-19 87.4 COG1373@1|root,COG1373@2|Bacteria,2HJ52@201174|Actinobacteria,4D2TQ@85004|Bifidobacteriales 201174|Actinobacteria S Domain of unknown function (DUF4143) - - - ko:K07133 - - - - ko00000 - - - AAA_14,DUF4143 GGPLMPOG_01001 547043.BIFPSEUDO_02371 1.89e-178 502.0 COG0330@1|root,COG0330@2|Bacteria,2GJ1U@201174|Actinobacteria,4CYTU@85004|Bifidobacteriales 201174|Actinobacteria O prohibitin homologues hflK GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - - - - - - - - - - Band_7 GGPLMPOG_01002 547043.BIFPSEUDO_02373 7.85e-59 181.0 COG0695@1|root,COG0695@2|Bacteria,2HZQB@201174|Actinobacteria,4D18H@85004|Bifidobacteriales 201174|Actinobacteria O Glutaredoxin - - - - - - - - - - - - Glutaredoxin GGPLMPOG_01003 547043.BIFPSEUDO_02374 9.91e-22 84.7 COG1123@1|root,COG4172@2|Bacteria,2H8A5@201174|Actinobacteria,4D2HM@85004|Bifidobacteriales 201174|Actinobacteria P Belongs to the ABC transporter superfamily - - - - - - - - - - - - - GGPLMPOG_01004 547043.BIFPSEUDO_02375 1.8e-97 284.0 COG0626@1|root,COG0626@2|Bacteria,2GJ5S@201174|Actinobacteria,4CZKK@85004|Bifidobacteriales 201174|Actinobacteria E Cys/Met metabolism PLP-dependent enzyme metC1 - 4.4.1.8 ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP GGPLMPOG_01005 1437608.BBIA_1357 3.25e-07 57.4 COG0626@1|root,COG0626@2|Bacteria,2GJ5S@201174|Actinobacteria,4CZKK@85004|Bifidobacteriales 201174|Actinobacteria E Cys/Met metabolism PLP-dependent enzyme metC1 - 4.4.1.8 ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP GGPLMPOG_01006 547043.BIFPSEUDO_02377 1.11e-282 772.0 COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,4CZCF@85004|Bifidobacteriales 201174|Actinobacteria E Aminotransferase class I and II - - 2.6.1.1,2.6.1.2,2.6.1.66,2.6.1.83 ko:K00812,ko:K08969,ko:K10206,ko:K14260,ko:K14261 ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00034,M00527 R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052,R07396,R07613 RC00006,RC00008,RC00036,RC01847 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 GGPLMPOG_01007 547043.BIFPSEUDO_02378 4.35e-134 382.0 COG2011@1|root,COG2011@2|Bacteria,2GY65@201174|Actinobacteria,4CZP5@85004|Bifidobacteriales 201174|Actinobacteria P Psort location CytoplasmicMembrane, score 9.99 - - - ko:K02072 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - BPD_transp_1 GGPLMPOG_01008 547043.BIFPSEUDO_02379 2.63e-243 669.0 COG1135@1|root,COG1135@2|Bacteria,2GJ9P@201174|Actinobacteria,4CZYI@85004|Bifidobacteriales 201174|Actinobacteria P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system metN - - ko:K02071 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - ABC_tran,NIL GGPLMPOG_01009 547043.BIFPSEUDO_02380 5.63e-196 545.0 COG1464@1|root,COG1464@2|Bacteria,2GMNI@201174|Actinobacteria,4CZAI@85004|Bifidobacteriales 201174|Actinobacteria M NLPA lipoprotein metQ - - ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 GGPLMPOG_01010 547043.BIFPSEUDO_02381 2.1e-256 702.0 COG1893@1|root,COG1893@2|Bacteria,2HZCX@201174|Actinobacteria,4CZN4@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 - - - ApbA,ApbA_C GGPLMPOG_01011 566552.BIFCAT_01784 1.51e-314 857.0 COG2211@1|root,COG2211@2|Bacteria,2GJZG@201174|Actinobacteria,4CZ93@85004|Bifidobacteriales 201174|Actinobacteria G Transporter major facilitator family protein - - - - - - - - - - - - MFS_1,MFS_2 GGPLMPOG_01012 566552.BIFCAT_01783 0.0 1984.0 COG1196@1|root,COG1208@1|root,COG1196@2|Bacteria,COG1208@2|Bacteria,2I2FS@201174|Actinobacteria,4D1DH@85004|Bifidobacteriales 201174|Actinobacteria JM Carbohydrate binding module (family 6) - - - - - - - - - - - - CBM_35,RicinB_lectin_2 GGPLMPOG_01013 566552.BIFCAT_01782 0.0 1349.0 COG3533@1|root,COG3533@2|Bacteria,2GM60@201174|Actinobacteria,4CYSU@85004|Bifidobacteriales 201174|Actinobacteria S Beta-L-arabinofuranosidase, GH127 - - 3.2.1.185 ko:K09955,ko:K18205 - - - - ko00000,ko01000 - GH127 - Glyco_hydro_127 GGPLMPOG_01014 566552.BIFCAT_01781 4.36e-204 564.0 COG0395@1|root,COG0395@2|Bacteria,2GJNJ@201174|Actinobacteria,4D0WS@85004|Bifidobacteriales 201174|Actinobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02026 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 GGPLMPOG_01015 566552.BIFCAT_01780 2.08e-191 534.0 COG1175@1|root,COG1175@2|Bacteria,2GKBJ@201174|Actinobacteria,4CZDV@85004|Bifidobacteriales 201174|Actinobacteria U Binding-protein-dependent transport system inner membrane component - - - ko:K02025,ko:K10189,ko:K10241 ko02010,map02010 M00199,M00206,M00207 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.23,3.A.1.1.4 - - BPD_transp_1 GGPLMPOG_01016 566552.BIFCAT_01779 4.04e-304 828.0 COG1653@1|root,COG1653@2|Bacteria,2HEH9@201174|Actinobacteria,4D1JK@85004|Bifidobacteriales 201174|Actinobacteria G Bacterial extracellular solute-binding protein - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_1 GGPLMPOG_01017 566552.BIFCAT_01778 3.21e-243 667.0 COG1609@1|root,COG1609@2|Bacteria,2GJV7@201174|Actinobacteria,4CZND@85004|Bifidobacteriales 201174|Actinobacteria K Periplasmic binding protein domain - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 GGPLMPOG_01018 566552.BIFCAT_01776 0.0 1434.0 COG3345@1|root,COG3345@2|Bacteria,2GJJ1@201174|Actinobacteria,4CZDM@85004|Bifidobacteriales 201174|Actinobacteria G Psort location Cytoplasmic, score 8.87 - - 3.2.1.22 ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 - R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 - - - Glyco_hydro_36N,Melibiase GGPLMPOG_01019 566552.BIFCAT_01775 5.31e-210 581.0 COG0834@1|root,COG0834@2|Bacteria,2GJH8@201174|Actinobacteria,4CZAC@85004|Bifidobacteriales 201174|Actinobacteria ET Bacterial periplasmic substrate-binding proteins glnH - - ko:K02030,ko:K10039 ko02010,map02010 M00228,M00236 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 GGPLMPOG_01020 566552.BIFCAT_01774 2.91e-191 531.0 COG1126@1|root,COG1126@2|Bacteria,2H1ZM@201174|Actinobacteria,4CZTK@85004|Bifidobacteriales 201174|Actinobacteria E ATP binding protein of ABC transporter for glutamate aspartate K02028 glnQ - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran GGPLMPOG_01021 566552.BIFCAT_01773 8.7e-157 440.0 COG0765@1|root,COG0765@2|Bacteria,2GN44@201174|Actinobacteria,4CZG7@85004|Bifidobacteriales 201174|Actinobacteria E Binding-protein-dependent transport system inner membrane component glnP - - ko:K02029,ko:K10040 ko02010,map02010 M00228,M00236 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 GGPLMPOG_01022 566552.BIFCAT_01772 3.01e-145 410.0 COG0765@1|root,COG0765@2|Bacteria,2GM0I@201174|Actinobacteria,4CZ8E@85004|Bifidobacteriales 201174|Actinobacteria E Binding-protein-dependent transport system inner membrane component glnP2 - - ko:K02029 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 GGPLMPOG_01023 566552.BIFCAT_01770 2.53e-146 412.0 COG3153@1|root,COG3153@2|Bacteria,2I45Q@201174|Actinobacteria,4D2WJ@85004|Bifidobacteriales 201174|Actinobacteria S Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_7 GGPLMPOG_01025 1437603.BMON_0921 1.31e-138 412.0 COG0582@1|root,COG0582@2|Bacteria,2HZF9@201174|Actinobacteria,4D08E@85004|Bifidobacteriales 201174|Actinobacteria L Phage integrase family - - - - - - - - - - - - Phage_int_SAM_3,Phage_integrase GGPLMPOG_01026 547043.BIFPSEUDO_03625 1.8e-83 247.0 2A3Y6@1|root,30SGI@2|Bacteria,2IM76@201174|Actinobacteria,4D10Z@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01027 566552.BIFCAT_00825 9.76e-125 357.0 COG0739@1|root,COG0739@2|Bacteria,2IQ64@201174|Actinobacteria,4D199@85004|Bifidobacteriales 201174|Actinobacteria M Peptidase family M23 - - - - - - - - - - - - Peptidase_M23 GGPLMPOG_01028 547043.BIFPSEUDO_03627 0.0 1191.0 COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4CYYC@85004|Bifidobacteriales 201174|Actinobacteria I AMP-binding enzyme fadD1 - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding GGPLMPOG_01029 547043.BIFPSEUDO_03628 0.0 962.0 COG4213@1|root,COG4213@2|Bacteria,2HZAK@201174|Actinobacteria,4CZCR@85004|Bifidobacteriales 201174|Actinobacteria G ABC transporter substrate-binding protein - - - - - - - - - - - - Peripla_BP_4 GGPLMPOG_01030 547043.BIFPSEUDO_03629 9.14e-305 829.0 COG0538@1|root,COG0538@2|Bacteria,2GM3D@201174|Actinobacteria,4CZ8V@85004|Bifidobacteriales 201174|Actinobacteria C Belongs to the isocitrate and isopropylmalate dehydrogenases family icd GO:0000287,GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006102,GO:0008150,GO:0008152,GO:0008270,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044464,GO:0045333,GO:0046487,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:0072350 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh GGPLMPOG_01031 547043.BIFPSEUDO_03630 1.07e-265 729.0 COG0516@1|root,COG0516@2|Bacteria,2GKVS@201174|Actinobacteria,4CZDK@85004|Bifidobacteriales 201174|Actinobacteria F IMP dehydrogenase family protein guaB3 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - IMPDH GGPLMPOG_01032 547043.BIFPSEUDO_03631 5.78e-139 392.0 COG2176@1|root,COG2176@2|Bacteria,2I2FU@201174|Actinobacteria,4D10C@85004|Bifidobacteriales 201174|Actinobacteria L Exonuclease, DNA polymerase III, epsilon subunit family dnaQ - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - BRCT,RNase_T GGPLMPOG_01033 547043.BIFPSEUDO_03634 4.18e-92 270.0 COG1823@1|root,COG1823@2|Bacteria,2I862@201174|Actinobacteria,4D08P@85004|Bifidobacteriales 201174|Actinobacteria U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - ko:K06956 - - - - ko00000 - - - SDF GGPLMPOG_01034 547043.BIFPSEUDO_03635 2.71e-316 863.0 COG1207@1|root,COG1207@2|Bacteria,2GJS1@201174|Actinobacteria,4CZ4C@85004|Bifidobacteriales 201174|Actinobacteria M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030260,GO:0035635,GO:0040007,GO:0043167,GO:0043169,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569 2.3.1.157,2.7.7.23 ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transf_3,NTP_transferase GGPLMPOG_01035 547043.BIFPSEUDO_03636 3.94e-88 259.0 COG0799@1|root,COG0799@2|Bacteria,2IKZ3@201174|Actinobacteria,4D11U@85004|Bifidobacteriales 201174|Actinobacteria J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation rsfS - - ko:K09710 - - - - ko00000,ko03009 - - - RsfS GGPLMPOG_01036 547043.BIFPSEUDO_03637 7.33e-183 508.0 COG0406@1|root,COG0406@2|Bacteria,2GJYU@201174|Actinobacteria,4CYXK@85004|Bifidobacteriales 201174|Actinobacteria G Phosphoglycerate mutase family gpmB GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0044237 3.1.3.85,5.4.2.11 ko:K01834,ko:K22306 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 GGPLMPOG_01037 547043.BIFPSEUDO_03638 2.54e-169 484.0 2DQFC@1|root,336HV@2|Bacteria,2I8B6@201174|Actinobacteria,4D309@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01039 547043.BIFPSEUDO_03641 6.91e-298 813.0 COG1510@1|root,COG3177@1|root,COG1510@2|Bacteria,COG3177@2|Bacteria,2HZGJ@201174|Actinobacteria,4D0D3@85004|Bifidobacteriales 201174|Actinobacteria K Fic/DOC family - - - - - - - - - - - - Fic GGPLMPOG_01040 547043.BIFPSEUDO_03644 7.89e-91 266.0 COG3576@1|root,COG3576@2|Bacteria,2IJK2@201174|Actinobacteria,4D0W8@85004|Bifidobacteriales 201174|Actinobacteria S Pfam:Pyridox_oxidase pdxH - - ko:K07006 - - - - ko00000 - - - Putative_PNPOx GGPLMPOG_01041 547043.BIFPSEUDO_03646 0.0 1051.0 COG4932@1|root,COG4932@2|Bacteria,2HVUZ@201174|Actinobacteria,4CZTB@85004|Bifidobacteriales 201174|Actinobacteria M domain protein - - - - - - - - - - - - GramPos_pilinBB,Gram_pos_anchor GGPLMPOG_01044 547043.BIFPSEUDO_03648 1.72e-210 580.0 COG0406@1|root,COG0406@2|Bacteria,2GJYU@201174|Actinobacteria,4CZI8@85004|Bifidobacteriales 201174|Actinobacteria G Phosphoglycerate mutase family gpmB GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0044237 3.1.3.85,5.4.2.11 ko:K01834,ko:K22306 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 GGPLMPOG_01045 547043.BIFPSEUDO_03649 1.48e-219 606.0 COG0598@1|root,COG0598@2|Bacteria,2HZ8V@201174|Actinobacteria,4CYWX@85004|Bifidobacteriales 201174|Actinobacteria P CorA-like Mg2+ transporter protein corA - - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - - CorA GGPLMPOG_01046 566552.BIFCAT_00803 2.74e-182 509.0 COG0834@1|root,COG0834@2|Bacteria,2I9PU@201174|Actinobacteria,4D09U@85004|Bifidobacteriales 201174|Actinobacteria ET Bacterial periplasmic substrate-binding proteins - - - ko:K10005 ko02010,map02010 M00233 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.9 - - SBP_bac_3 GGPLMPOG_01047 547043.BIFPSEUDO_03651 0.0 2055.0 COG0495@1|root,COG0495@2|Bacteria,2GJI1@201174|Actinobacteria,4CZHV@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the class-I aminoacyl-tRNA synthetase family leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 GGPLMPOG_01048 547043.BIFPSEUDO_03652 4.58e-137 393.0 COG1555@1|root,COG1555@2|Bacteria,2IQDC@201174|Actinobacteria,4D176@85004|Bifidobacteriales 201174|Actinobacteria L Helix-hairpin-helix motif comEA - - ko:K02237 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - HHH_3,SLBB GGPLMPOG_01049 547043.BIFPSEUDO_03653 0.0 1120.0 COG0658@1|root,COG0658@2|Bacteria,2GJGR@201174|Actinobacteria,4CZ6X@85004|Bifidobacteriales 201174|Actinobacteria S Competence protein comEC - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B GGPLMPOG_01050 547043.BIFPSEUDO_03654 3.52e-227 626.0 COG1466@1|root,COG1466@2|Bacteria,2GNMZ@201174|Actinobacteria,4CZ07@85004|Bifidobacteriales 201174|Actinobacteria L DNA polymerase III delta subunit holA - 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta GGPLMPOG_01051 566552.BIFCAT_00798 7.17e-119 343.0 COG0802@1|root,COG0802@2|Bacteria,2IKV2@201174|Actinobacteria,4D0PH@85004|Bifidobacteriales 201174|Actinobacteria S Threonylcarbamoyl adenosine biosynthesis protein TsaE tsaE GO:0008150,GO:0040007 - ko:K06925 - - - - ko00000,ko03016 - - - TsaE GGPLMPOG_01052 547043.BIFPSEUDO_03657 5.66e-189 525.0 COG1214@1|root,COG1214@2|Bacteria,2GMTM@201174|Actinobacteria,4D0A2@85004|Bifidobacteriales 201174|Actinobacteria O Glycoprotease family yeaZ GO:0002949,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0071944,GO:0090304,GO:1901360 - ko:K14742 - - - - ko00000,ko03016 - - - Peptidase_M22 GGPLMPOG_01053 547043.BIFPSEUDO_03658 7.04e-133 377.0 COG0454@1|root,COG0456@2|Bacteria,2IM9R@201174|Actinobacteria,4D0Q0@85004|Bifidobacteriales 201174|Actinobacteria K FR47-like protein rimI GO:0003674,GO:0003824,GO:0004596,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1 GGPLMPOG_01054 547043.BIFPSEUDO_03659 1.13e-250 687.0 COG0533@1|root,COG0533@2|Bacteria,2GJ98@201174|Actinobacteria,4CZ0K@85004|Bifidobacteriales 201174|Actinobacteria O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction tsaD GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 ko:K01409 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Acetyltransf_1,Peptidase_M22 GGPLMPOG_01056 657322.FPR_07630 5.47e-152 430.0 COG1246@1|root,COG1246@2|Bacteria,1TRN6@1239|Firmicutes,2484V@186801|Clostridia,3WGHV@541000|Ruminococcaceae 186801|Clostridia E YoaP-like yoaP - - - - - - - - - - - Acetyltransf_1,YoaP GGPLMPOG_01057 547043.BIFPSEUDO_03662 7.51e-238 652.0 COG3049@1|root,COG3049@2|Bacteria,2GK9Z@201174|Actinobacteria,4CZNU@85004|Bifidobacteriales 201174|Actinobacteria M Linear amide C-N hydrolase, choloylglycine hydrolase family protein cbh - 3.5.1.24 ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 - R02797,R03975,R03977,R04486,R04487,R05835 RC00090,RC00096 ko00000,ko00001,ko01000 - - - CBAH GGPLMPOG_01058 547043.BIFPSEUDO_03663 3.51e-154 434.0 COG4721@1|root,COG4721@2|Bacteria,2H5VZ@201174|Actinobacteria,4CZ6M@85004|Bifidobacteriales 201174|Actinobacteria S ABC-type cobalt transport system, permease component - - - ko:K16925 - M00582 - - ko00000,ko00002,ko02000 3.A.1.30 - - ABC_cobalt GGPLMPOG_01059 547043.BIFPSEUDO_03666 2.39e-93 273.0 COG0789@1|root,COG0789@2|Bacteria,2HZK3@201174|Actinobacteria,4D0RM@85004|Bifidobacteriales 201174|Actinobacteria K MerR family regulatory protein - - - - - - - - - - - - MerR,MerR_1 GGPLMPOG_01060 547043.BIFPSEUDO_03667 2.21e-253 694.0 COG1063@1|root,COG1063@2|Bacteria,2GISW@201174|Actinobacteria,4CZJY@85004|Bifidobacteriales 201174|Actinobacteria C Zinc-binding dehydrogenase adh - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_N_assoc,ADH_zinc_N GGPLMPOG_01061 547043.BIFPSEUDO_03668 3.1e-184 511.0 COG0599@1|root,COG0599@2|Bacteria,2GITB@201174|Actinobacteria,4CZBK@85004|Bifidobacteriales 201174|Actinobacteria S Carboxymuconolactone decarboxylase family - - 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R03470 RC00938 ko00000,ko00001,ko01000 - - - CMD GGPLMPOG_01062 547043.BIFPSEUDO_03669 9.08e-283 771.0 COG0620@1|root,COG0620@2|Bacteria,2I9RI@201174|Actinobacteria,4CZKN@85004|Bifidobacteriales 201174|Actinobacteria E Psort location Cytoplasmic, score 8.87 - - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 GGPLMPOG_01063 547043.BIFPSEUDO_03670 5.77e-100 290.0 COG2246@1|root,COG2246@2|Bacteria,2II4Y@201174|Actinobacteria,4D0YG@85004|Bifidobacteriales 201174|Actinobacteria S Psort location CytoplasmicMembrane, score - - - - - - - - - - - - GtrA GGPLMPOG_01064 547043.BIFPSEUDO_03671 3.16e-234 645.0 COG0053@1|root,COG0053@2|Bacteria,2GKSG@201174|Actinobacteria,4D05T@85004|Bifidobacteriales 201174|Actinobacteria P Cation efflux family - - - - - - - - - - - - Cation_efflux,ZT_dimer GGPLMPOG_01067 547043.BIFPSEUDO_03674 1.01e-181 509.0 2DDMI@1|root,2ZIJN@2|Bacteria,2ICIR@201174|Actinobacteria,4D112@85004|Bifidobacteriales 201174|Actinobacteria - - - - - ko:K03646 - - - - ko00000,ko02000 2.C.1.2 - - - GGPLMPOG_01068 547043.BIFPSEUDO_03675 6.87e-204 566.0 2BAGB@1|root,323WV@2|Bacteria,2H8N0@201174|Actinobacteria,4D2EW@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01069 547043.BIFPSEUDO_03676 5.16e-148 420.0 COG1694@1|root,COG3956@2|Bacteria,2GNKC@201174|Actinobacteria,4CZ9U@85004|Bifidobacteriales 201174|Actinobacteria S Psort location Cytoplasmic, score 8.87 mazG GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0022607,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0035539,GO:0042454,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044464,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0047693,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66 ko:K02428,ko:K02499 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000,ko03036 - - - MazG GGPLMPOG_01070 547043.BIFPSEUDO_03678 0.0 961.0 COG3579@1|root,COG3579@2|Bacteria,2HCVR@201174|Actinobacteria,4CZD8@85004|Bifidobacteriales 201174|Actinobacteria E Peptidase C1-like family - - 3.4.22.40 ko:K01372 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C1_2 GGPLMPOG_01071 547043.BIFPSEUDO_03679 1.3e-236 650.0 COG0517@1|root,COG0517@2|Bacteria,2HZMJ@201174|Actinobacteria,4D0Y3@85004|Bifidobacteriales 201174|Actinobacteria S IMP dehydrogenase activity - - - - - - - - - - - - CBS GGPLMPOG_01072 547043.BIFPSEUDO_03680 0.0 1033.0 COG0488@1|root,COG0488@2|Bacteria,2GKQ4@201174|Actinobacteria,4CYS2@85004|Bifidobacteriales 201174|Actinobacteria S ABC transporter ybiT - - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_Xtn,DLIC GGPLMPOG_01073 547043.BIFPSEUDO_03681 9.57e-145 407.0 COG1335@1|root,COG1335@2|Bacteria,2IFQW@201174|Actinobacteria,4CYTT@85004|Bifidobacteriales 201174|Actinobacteria Q Isochorismatase family pncA GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006769,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0071704,GO:0072524,GO:1901360,GO:1901564 3.5.1.19 ko:K08281 ko00760,ko01100,map00760,map01100 - R01268 RC00100 ko00000,ko00001,ko01000 - - - Isochorismatase GGPLMPOG_01074 547043.BIFPSEUDO_03682 4.53e-88 258.0 COG0350@1|root,COG0350@2|Bacteria,2IHXW@201174|Actinobacteria,4D10F@85004|Bifidobacteriales 201174|Actinobacteria L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated ogt - 2.1.1.63 ko:K00567,ko:K07443 - - - - ko00000,ko01000,ko03400 - - - DNA_binding_1 GGPLMPOG_01076 547043.BIFPSEUDO_03685 2.77e-19 78.2 2B5HZ@1|root,31YCP@2|Bacteria,2H0JJ@201174|Actinobacteria,4D1QQ@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01077 547043.BIFPSEUDO_03686 0.0 946.0 2ETEZ@1|root,33KYW@2|Bacteria,2HXGA@201174|Actinobacteria,4CZSC@85004|Bifidobacteriales 201174|Actinobacteria S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - DUF3375 GGPLMPOG_01078 547043.BIFPSEUDO_03687 3.96e-180 502.0 2APK1@1|root,31EP8@2|Bacteria,2IEAB@201174|Actinobacteria,4D0C3@85004|Bifidobacteriales 201174|Actinobacteria S Domain of unknown function (DUF4194) - - - - - - - - - - - - DUF4194 GGPLMPOG_01079 547043.BIFPSEUDO_03688 0.0 1843.0 COG4913@1|root,COG4913@2|Bacteria,2GMIP@201174|Actinobacteria,4CYWR@85004|Bifidobacteriales 201174|Actinobacteria S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - AAA_29,SbcCD_C GGPLMPOG_01080 547043.BIFPSEUDO_03689 1.76e-281 769.0 COG4924@1|root,COG4924@2|Bacteria,2IB33@201174|Actinobacteria,4D02A@85004|Bifidobacteriales 201174|Actinobacteria S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - DUF2220,DUF3322 GGPLMPOG_01081 547043.BIFPSEUDO_03690 0.0 1998.0 COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,4CYRU@85004|Bifidobacteriales 201174|Actinobacteria L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA GO:0000018,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0071944,GO:0080090 - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran GGPLMPOG_01082 547043.BIFPSEUDO_03691 0.0 1498.0 COG0322@1|root,COG0322@2|Bacteria,2GIS4@201174|Actinobacteria,4CYVX@85004|Bifidobacteriales 201174|Actinobacteria L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0040007,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N GGPLMPOG_01083 547043.BIFPSEUDO_03692 2.41e-233 641.0 COG0169@1|root,COG0169@2|Bacteria,2GPQQ@201174|Actinobacteria,4CZCM@85004|Bifidobacteriales 201174|Actinobacteria E Shikimate dehydrogenase substrate binding domain aroE GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv2552c Shikimate_DH,Shikimate_dh_N GGPLMPOG_01084 547043.BIFPSEUDO_03693 6.26e-218 602.0 COG1660@1|root,COG1660@2|Bacteria,2GMWB@201174|Actinobacteria,4CZ70@85004|Bifidobacteriales 201174|Actinobacteria S Displays ATPase and GTPase activities yvcJ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K06958 - - - - ko00000,ko03019 - - - ATP_bind_2 GGPLMPOG_01085 547043.BIFPSEUDO_03694 2.1e-219 606.0 COG1481@1|root,COG1481@2|Bacteria,2GJZU@201174|Actinobacteria,4CYTD@85004|Bifidobacteriales 201174|Actinobacteria K May be required for sporulation whiA GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0043937,GO:0044464,GO:0050789,GO:0050793,GO:0065007,GO:0071944 - ko:K09762 - - - - ko00000 - - - HTH_WhiA,LAGLIDADG_WhiA,WhiA_N GGPLMPOG_01086 547043.BIFPSEUDO_03695 3.72e-281 769.0 COG0126@1|root,COG0126@2|Bacteria,2GJC6@201174|Actinobacteria,4CZJ3@85004|Bifidobacteriales 201174|Actinobacteria F Phosphoglycerate kinase pgk GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044464,GO:0071944 2.7.2.3,5.3.1.1 ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01015,R01512 RC00002,RC00043,RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGK GGPLMPOG_01087 547043.BIFPSEUDO_03696 4.01e-191 530.0 COG0149@1|root,COG0149@2|Bacteria,2GJXZ@201174|Actinobacteria,4CYSG@85004|Bifidobacteriales 201174|Actinobacteria G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - TIM GGPLMPOG_01088 1435051.BMOU_1040 2.47e-44 144.0 COG1314@1|root,COG1314@2|Bacteria,2GR31@201174|Actinobacteria,4D16U@85004|Bifidobacteriales 201174|Actinobacteria U Preprotein translocase SecG subunit secG GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecG GGPLMPOG_01089 547043.BIFPSEUDO_03698 4.46e-226 622.0 COG0561@1|root,COG0561@2|Bacteria,2HZYB@201174|Actinobacteria,4CZQW@85004|Bifidobacteriales 201174|Actinobacteria S Sucrose-6F-phosphate phosphohydrolase - - - - - - - - - - - - Hydrolase_3 GGPLMPOG_01090 547043.BIFPSEUDO_03699 0.0 1032.0 COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,4CZVJ@85004|Bifidobacteriales 201174|Actinobacteria E Aminotransferase, class I II aspC GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.6.1.1,2.6.1.2,2.6.1.66 ko:K00812,ko:K08969,ko:K14260 ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00034 R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052,R07396 RC00006,RC00008,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - iNJ661.Rv0337c Aminotran_1_2 GGPLMPOG_01091 158787.BSCA_1203 3.51e-11 63.9 COG3201@1|root,COG3201@2|Bacteria,2IBT8@201174|Actinobacteria,4D03Z@85004|Bifidobacteriales 201174|Actinobacteria H Nicotinamide mononucleotide transporter - - - ko:K03811 - - - - ko00000,ko02000 4.B.1.1 - - NMN_transporter GGPLMPOG_01092 547043.BIFPSEUDO_03701 3.14e-39 135.0 COG3201@1|root,COG3201@2|Bacteria,2IBT8@201174|Actinobacteria,4D03Z@85004|Bifidobacteriales 201174|Actinobacteria H Nicotinamide mononucleotide transporter - - - ko:K03811 - - - - ko00000,ko02000 4.B.1.1 - - NMN_transporter GGPLMPOG_01093 547043.BIFPSEUDO_03701 3.29e-89 264.0 COG3201@1|root,COG3201@2|Bacteria,2IBT8@201174|Actinobacteria,4D03Z@85004|Bifidobacteriales 201174|Actinobacteria H Nicotinamide mononucleotide transporter - - - ko:K03811 - - - - ko00000,ko02000 4.B.1.1 - - NMN_transporter GGPLMPOG_01094 547043.BIFPSEUDO_03704 4.03e-57 177.0 COG3172@1|root,COG3172@2|Bacteria,2HZW3@201174|Actinobacteria,4D1ZG@85004|Bifidobacteriales 2|Bacteria H ATPase kinase involved in NAD metabolism nadR - - - - - - - - - - - AAA_28,CTP_transf_like GGPLMPOG_01095 547043.BIFPSEUDO_03705 4.69e-260 713.0 COG0176@1|root,COG0176@2|Bacteria,2GMF9@201174|Actinobacteria,4CZ3J@85004|Bifidobacteriales 201174|Actinobacteria H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway tal - 2.2.1.2 ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 - - - TAL_FSA GGPLMPOG_01096 547043.BIFPSEUDO_03706 0.0 1410.0 COG0021@1|root,COG0021@2|Bacteria,2GJ1K@201174|Actinobacteria,4CZ64@85004|Bifidobacteriales 201174|Actinobacteria H Belongs to the transketolase family tkt GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C,Transketolase_N GGPLMPOG_01097 547043.BIFPSEUDO_03707 3.96e-251 691.0 COG1420@1|root,COG1420@2|Bacteria,2GKF5@201174|Actinobacteria,4CZK3@85004|Bifidobacteriales 201174|Actinobacteria K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons hrcA GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K03705 - - - - ko00000,ko03000 - - - HTH_DeoR,HrcA GGPLMPOG_01098 547043.BIFPSEUDO_03708 5.73e-264 724.0 COG0484@1|root,COG0484@2|Bacteria,2GK69@201174|Actinobacteria,4D03K@85004|Bifidobacteriales 201174|Actinobacteria O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ - - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG GGPLMPOG_01099 1437608.BBIA_2597 5.92e-30 110.0 2E4T7@1|root,32ZMK@2|Bacteria,2GVRN@201174|Actinobacteria,4D1F6@85004|Bifidobacteriales 201174|Actinobacteria S Putative lactococcus lactis phage r1t holin - - - - - - - - - - - - Phage_r1t_holin GGPLMPOG_01100 158787.BSCA_1068 3.66e-148 427.0 COG3023@1|root,COG3023@2|Bacteria,2GJ9M@201174|Actinobacteria,4D0SC@85004|Bifidobacteriales 201174|Actinobacteria V Ami_2 - - - - - - - - - - - - Amidase_2,CW_7 GGPLMPOG_01104 1437610.BREU_1370 1.28e-42 154.0 COG3468@1|root,COG3468@2|Bacteria,2GXAB@201174|Actinobacteria,4D1NP@85004|Bifidobacteriales 201174|Actinobacteria MU outer membrane autotransporter barrel domain protein - - - - - - - - - - - - Collagen GGPLMPOG_01105 158787.BSCA_0721 1.11e-48 157.0 2BJPU@1|root,32E1F@2|Bacteria,2GZ2E@201174|Actinobacteria,4D1PK@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01106 1680.BADO_1224 1.37e-111 331.0 COG0582@1|root,COG0582@2|Bacteria 2|Bacteria L DNA integration - - - - - - - - - - - - Phage_int_SAM_3,Phage_integrase GGPLMPOG_01110 521095.Apar_0592 1.04e-28 117.0 2CA4H@1|root,3342S@2|Bacteria,2GRNF@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01112 78345.BMERY_0868 1.95e-94 300.0 2BPU9@1|root,32IMR@2|Bacteria,2IG69@201174|Actinobacteria,4D0RH@85004|Bifidobacteriales 201174|Actinobacteria S Psort location Cytoplasmic, score - - - - - - - - - - - - Sipho_Gp37 GGPLMPOG_01114 1688.BCUN_0388 5.81e-118 400.0 COG5283@1|root,COG5412@1|root,COG5283@2|Bacteria,COG5412@2|Bacteria,2H75F@201174|Actinobacteria,4CZ1P@85004|Bifidobacteriales 201174|Actinobacteria NT phage tail tape measure protein - - - - - - - - - - - - - GGPLMPOG_01117 78346.BRUM_0390 9.73e-73 226.0 2F7JH@1|root,34004@2|Bacteria,2INSW@201174|Actinobacteria,4D1E3@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01119 78346.BRUM_0392 1.47e-38 130.0 2912G@1|root,2ZNQ0@2|Bacteria,2GX8Y@201174|Actinobacteria,4D1TI@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - HK97-gp10_like GGPLMPOG_01120 1688.BCUN_0394 6.79e-41 139.0 2B5F6@1|root,31Y9P@2|Bacteria,2GVMG@201174|Actinobacteria,4D1JP@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01121 1688.BCUN_0395 2.38e-24 100.0 28XFC@1|root,2ZJCX@2|Bacteria,2IPP5@201174|Actinobacteria,4D165@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01122 1437605.BACT_1073 3.08e-124 372.0 COG4653@1|root,COG4653@2|Bacteria,2ICZP@201174|Actinobacteria,4CZSG@85004|Bifidobacteriales 201174|Actinobacteria S Phage capsid family - - - - - - - - - - - - Peptidase_S78,Phage_capsid GGPLMPOG_01124 1688.BCUN_0399 3.62e-59 201.0 COG4695@1|root,COG4695@2|Bacteria,2I9PX@201174|Actinobacteria,4D0K9@85004|Bifidobacteriales 201174|Actinobacteria S Phage portal protein - - - - - - - - - - - - Phage_portal GGPLMPOG_01125 1688.BCUN_0399 2.1e-11 69.7 COG4695@1|root,COG4695@2|Bacteria,2I9PX@201174|Actinobacteria,4D0K9@85004|Bifidobacteriales 201174|Actinobacteria S Phage portal protein - - - - - - - - - - - - Phage_portal GGPLMPOG_01126 78346.BRUM_0399 1.91e-279 776.0 COG4626@1|root,COG4626@2|Bacteria,2IB7D@201174|Actinobacteria,4D0CK@85004|Bifidobacteriales 201174|Actinobacteria S Terminase - - - - - - - - - - - - Terminase_1 GGPLMPOG_01129 78346.BRUM_0401 2.47e-51 165.0 28X4S@1|root,2ZJ38@2|Bacteria,2GZYB@201174|Actinobacteria,4D1QM@85004|Bifidobacteriales 201174|Actinobacteria L HNH nucleases - - - - - - - - - - - - HNH GGPLMPOG_01130 158787.BSCA_0747 9.3e-124 359.0 COG2023@1|root,COG2023@2|Bacteria,2GW8Y@201174|Actinobacteria,4D1FV@85004|Bifidobacteriales 201174|Actinobacteria J tRNA 5'-leader removal - - - - - - - - - - - - - GGPLMPOG_01136 158787.BSCA_0751 0.0 1269.0 COG0467@1|root,COG0467@2|Bacteria,2I2HD@201174|Actinobacteria,4D242@85004|Bifidobacteriales 201174|Actinobacteria T Bifunctional DNA primase/polymerase, N-terminal - - - - - - - - - - - - AAA_25,Prim-Pol GGPLMPOG_01137 158787.BSCA_0752 3.42e-115 339.0 COG0629@1|root,COG0629@2|Bacteria,2GTDH@201174|Actinobacteria,4D1D1@85004|Bifidobacteriales 201174|Actinobacteria L single-stranded DNA binding - - - - - - - - - - - - - GGPLMPOG_01138 158787.BSCA_0753 4.52e-209 581.0 2E37I@1|root,32Y78@2|Bacteria,2IKDS@201174|Actinobacteria,4CZQ1@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - PDDEXK_1 GGPLMPOG_01140 158787.BSCA_0755 1.42e-29 111.0 28VJK@1|root,2ZHMZ@2|Bacteria,2GSC0@201174|Actinobacteria,4D1H4@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01142 158787.BSCA_0758 2.94e-69 213.0 COG4570@1|root,COG4570@2|Bacteria,2GQT6@201174|Actinobacteria,4D1DZ@85004|Bifidobacteriales 201174|Actinobacteria L Endodeoxyribonuclease RusA - - - - - - - - - - - - RusA GGPLMPOG_01147 1437610.BREU_1423 8.11e-17 77.8 2DKM6@1|root,309WJ@2|Bacteria,2HATM@201174|Actinobacteria,4D2MN@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01148 158787.BSCA_0773 1.46e-69 213.0 2C5TS@1|root,2ZX0Y@2|Bacteria,2IT81@201174|Actinobacteria,4D1BF@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01150 1437609.BCAL_1183 2.6e-145 424.0 COG4974@1|root,COG4974@2|Bacteria,2HD2H@201174|Actinobacteria,4D2VK@85004|Bifidobacteriales 201174|Actinobacteria L Phage integrase family - - - - - - - - - - - - Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase GGPLMPOG_01151 547043.BIFPSEUDO_03709 1.58e-201 556.0 COG3001@1|root,COG3001@2|Bacteria,2GW7W@201174|Actinobacteria,4CZ4W@85004|Bifidobacteriales 201174|Actinobacteria G Fructosamine kinase - - - - - - - - - - - - Fructosamin_kin GGPLMPOG_01152 547043.BIFPSEUDO_03710 1.44e-199 554.0 COG1968@1|root,COG1968@2|Bacteria,2GJVG@201174|Actinobacteria,4CZ83@85004|Bifidobacteriales 201174|Actinobacteria V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin uppP - 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - BacA GGPLMPOG_01153 547043.BIFPSEUDO_03711 5.61e-200 553.0 COG1938@1|root,COG1938@2|Bacteria,2GK10@201174|Actinobacteria,4CYSJ@85004|Bifidobacteriales 201174|Actinobacteria S PAC2 family - - - - - - - - - - - - PAC2 GGPLMPOG_01161 547043.BIFPSEUDO_03719 3.74e-48 153.0 2B2IQ@1|root,31V3U@2|Bacteria,2GUXU@201174|Actinobacteria,4D1EY@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01162 547043.BIFPSEUDO_03720 2.22e-98 286.0 COG1716@1|root,COG1716@2|Bacteria,2GK99@201174|Actinobacteria,4D0R3@85004|Bifidobacteriales 201174|Actinobacteria T Inner membrane component of T3SS, cytoplasmic domain garA GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006110,GO:0006140,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010563,GO:0010675,GO:0010677,GO:0016020,GO:0016310,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0030312,GO:0030808,GO:0030809,GO:0030811,GO:0030812,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031330,GO:0036211,GO:0042325,GO:0042326,GO:0042802,GO:0043170,GO:0043412,GO:0043457,GO:0043467,GO:0043470,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045820,GO:0045912,GO:0045934,GO:0045936,GO:0045980,GO:0046777,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051174,GO:0051193,GO:0051195,GO:0051196,GO:0051198,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1900371,GO:1900372,GO:1900542,GO:1900543,GO:1901564,GO:1903578,GO:1903579,GO:2001169,GO:2001170 - - - - - - - - - - FHA,Yop-YscD_cpl,zinc_ribbon_2 GGPLMPOG_01163 547043.BIFPSEUDO_03721 5.29e-145 409.0 COG0789@1|root,COG0789@2|Bacteria,2GM67@201174|Actinobacteria,4CZ0X@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn_helix, mercury resistance merR2 - - - - - - - - - - - MerR_1 GGPLMPOG_01164 547043.BIFPSEUDO_03722 1.54e-80 239.0 29TZI@1|root,30F8H@2|Bacteria,2ISJH@201174|Actinobacteria,4D0Z6@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01165 547043.BIFPSEUDO_03723 5.93e-181 502.0 COG0546@1|root,COG0546@2|Bacteria,2HFGX@201174|Actinobacteria,4CYSF@85004|Bifidobacteriales 201174|Actinobacteria S HAD-hyrolase-like nt5e GO:0003674,GO:0003824,GO:0004672,GO:0004713,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018108,GO:0018193,GO:0018212,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0071704,GO:0140096,GO:1901564 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 GGPLMPOG_01166 547043.BIFPSEUDO_03724 9.13e-81 239.0 2CNY9@1|root,32SI2@2|Bacteria,2IMK6@201174|Actinobacteria,4D0V5@85004|Bifidobacteriales 201174|Actinobacteria K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters rbpA GO:0001000,GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0043167,GO:0043169,GO:0043175,GO:0045893,GO:0045935,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070063,GO:0080090,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - - - - - - - - - - RbpA GGPLMPOG_01167 547043.BIFPSEUDO_03725 0.0 1703.0 COG4581@1|root,COG4581@2|Bacteria,2GJEX@201174|Actinobacteria,4CZEC@85004|Bifidobacteriales 201174|Actinobacteria L DEAD DEAH box helicase helY GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - ko:K03727 - - - - ko00000,ko01000 - - - DEAD,DSHCT,Helicase_C,rRNA_proc-arch GGPLMPOG_01168 547043.BIFPSEUDO_03726 2.4e-73 219.0 2B5BE@1|root,31Y5K@2|Bacteria,2IQT5@201174|Actinobacteria,4D17A@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01169 547043.BIFPSEUDO_03727 0.0 1231.0 COG2378@1|root,COG2378@2|Bacteria,2I8M5@201174|Actinobacteria,4CZWF@85004|Bifidobacteriales 201174|Actinobacteria K WYL domain - - - - - - - - - - - - WYL GGPLMPOG_01170 566552.BIFCAT_00732 0.0 916.0 COG4284@1|root,COG4284@2|Bacteria,2I2G3@201174|Actinobacteria,4CYTQ@85004|Bifidobacteriales 201174|Actinobacteria G UTP-glucose-1-phosphate uridylyltransferase ugp - 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 - - - UDPGP GGPLMPOG_01172 547043.BIFPSEUDO_03731 8.64e-92 268.0 2AXTZ@1|root,31PV0@2|Bacteria,2IMJI@201174|Actinobacteria,4D12E@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01173 547043.BIFPSEUDO_03732 0.0 1373.0 COG0283@1|root,COG1160@1|root,COG0283@2|Bacteria,COG1160@2|Bacteria,2GJ8J@201174|Actinobacteria,4CYSE@85004|Bifidobacteriales 201174|Actinobacteria F GTPase that plays an essential role in the late steps of ribosome biogenesis der GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - ko:K03977 - - - - ko00000,ko03009 - - - Cytidylate_kin,KH_dom-like,MMR_HSR1 GGPLMPOG_01174 547043.BIFPSEUDO_03733 9.79e-184 511.0 COG1187@1|root,COG1187@2|Bacteria,2GJ4N@201174|Actinobacteria,4CZGG@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the pseudouridine synthase RsuA family rluB GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.22 ko:K06178,ko:K06183 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 GGPLMPOG_01175 547043.BIFPSEUDO_03734 8.38e-208 576.0 COG0580@1|root,COG0580@2|Bacteria,2HZ9W@201174|Actinobacteria,4CZ5Q@85004|Bifidobacteriales 201174|Actinobacteria U Belongs to the MIP aquaporin (TC 1.A.8) family - - - ko:K06188 - - - - ko00000,ko02000 1.A.8 - - MIP GGPLMPOG_01176 78346.BRUM_1030 1.69e-48 155.0 2AXAE@1|root,31P9H@2|Bacteria,2IQKC@201174|Actinobacteria,4D18B@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - DUF3017 GGPLMPOG_01177 547043.BIFPSEUDO_03735 0.0 1074.0 COG0138@1|root,COG0138@2|Bacteria,2GJWU@201174|Actinobacteria,4CZ3P@85004|Bifidobacteriales 201174|Actinobacteria F Bifunctional purine biosynthesis protein PurH purH GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AICARFT_IMPCHas,MGS GGPLMPOG_01178 547043.BIFPSEUDO_03736 0.0 868.0 2EKVE@1|root,33EIZ@2|Bacteria,2HZ8H@201174|Actinobacteria,4CYRN@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01179 566552.BIFCAT_00724 1.1e-205 570.0 COG0074@1|root,COG0074@2|Bacteria,2GK00@201174|Actinobacteria,4CYX1@85004|Bifidobacteriales 201174|Actinobacteria C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit sucD GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 6.2.1.5 ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - CoA_binding,Ligase_CoA GGPLMPOG_01180 547043.BIFPSEUDO_03738 5.48e-281 768.0 COG0045@1|root,COG0045@2|Bacteria,2GKSB@201174|Actinobacteria,4CZCQ@85004|Bifidobacteriales 201174|Actinobacteria F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit sucC GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp_2,Ligase_CoA GGPLMPOG_01181 547043.BIFPSEUDO_03739 5.27e-130 370.0 COG0503@1|root,COG0503@2|Bacteria,2IM7C@201174|Actinobacteria,4CZ9H@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis apt GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 - R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 - - - Pribosyltran GGPLMPOG_01182 547043.BIFPSEUDO_03740 3.98e-83 246.0 COG1862@1|root,COG1862@2|Bacteria,2IKUJ@201174|Actinobacteria,4D139@85004|Bifidobacteriales 201174|Actinobacteria U Preprotein translocase subunit yajC - - ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - YajC GGPLMPOG_01183 547043.BIFPSEUDO_03741 3.38e-256 702.0 COG2255@1|root,COG2255@2|Bacteria,2GJZF@201174|Actinobacteria,4CZGU@85004|Bifidobacteriales 201174|Actinobacteria L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing ruvB GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N GGPLMPOG_01184 547043.BIFPSEUDO_03742 1.34e-137 390.0 COG0632@1|root,COG0632@2|Bacteria,2GN17@201174|Actinobacteria,4CZCE@85004|Bifidobacteriales 201174|Actinobacteria L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB ruvA GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009378,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N GGPLMPOG_01185 547043.BIFPSEUDO_03743 2.73e-129 368.0 COG0817@1|root,COG0817@2|Bacteria,2GJI5@201174|Actinobacteria,4CZ79@85004|Bifidobacteriales 201174|Actinobacteria L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group ruvC GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 ko:K01159 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvC GGPLMPOG_01186 547043.BIFPSEUDO_03744 2.38e-172 481.0 COG0217@1|root,COG0217@2|Bacteria,2GJ4G@201174|Actinobacteria,4CZ9X@85004|Bifidobacteriales 201174|Actinobacteria K transcriptional regulatory protein yebC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Transcrip_reg GGPLMPOG_01187 547043.BIFPSEUDO_03745 2.88e-144 408.0 COG0558@1|root,COG0558@2|Bacteria,2GYKW@201174|Actinobacteria,4D0NB@85004|Bifidobacteriales 201174|Actinobacteria I CDP-alcohol phosphatidyltransferase pgsA1 GO:0003674,GO:0003824,GO:0003881,GO:0003882,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.11,2.7.8.5 ko:K00995,ko:K00999 ko00562,ko00564,ko01100,ko04070,map00562,map00564,map01100,map04070 - R01801,R01802 RC00002,RC00017,RC00078,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf GGPLMPOG_01188 547043.BIFPSEUDO_03746 0.0 1361.0 COG0441@1|root,COG0441@2|Bacteria,2GKTC@201174|Actinobacteria,4CZD3@85004|Bifidobacteriales 201174|Actinobacteria J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA_SAD GGPLMPOG_01189 547043.BIFPSEUDO_03747 1.53e-180 504.0 COG3879@1|root,COG3879@2|Bacteria,2GJ3C@201174|Actinobacteria,4CYYH@85004|Bifidobacteriales 201174|Actinobacteria S Bacterial protein of unknown function (DUF881) - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - - - - - - - - - - DUF881 GGPLMPOG_01190 547043.BIFPSEUDO_03748 2.68e-64 197.0 COG3856@1|root,COG3856@2|Bacteria,2IKJW@201174|Actinobacteria,4D12G@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF1290) sbp - - - - - - - - - - - DUF1290 GGPLMPOG_01191 547043.BIFPSEUDO_03749 3.77e-221 611.0 COG3879@1|root,COG3879@2|Bacteria,2GMS5@201174|Actinobacteria,4CZ72@85004|Bifidobacteriales 201174|Actinobacteria S Bacterial protein of unknown function (DUF881) - GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - - - - - - - - - - DUF881 GGPLMPOG_01192 547043.BIFPSEUDO_03750 1.2e-133 379.0 COG0558@1|root,COG0558@2|Bacteria,2GM3F@201174|Actinobacteria,4CZGD@85004|Bifidobacteriales 201174|Actinobacteria I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pgsA2 GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 - R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf GGPLMPOG_01193 547043.BIFPSEUDO_03751 2.06e-198 550.0 COG0040@1|root,COG0040@2|Bacteria,2GNAX@201174|Actinobacteria,4CZ66@85004|Bifidobacteriales 201174|Actinobacteria F ATP phosphoribosyltransferase hisG GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002,ko01000 - - - HisG,HisG_C GGPLMPOG_01194 547043.BIFPSEUDO_03752 1.2e-54 171.0 COG0140@1|root,COG0140@2|Bacteria,2IQ4D@201174|Actinobacteria,4D108@85004|Bifidobacteriales 201174|Actinobacteria E Phosphoribosyl-ATP pyrophosphohydrolase hisE GO:0000287,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0009605,GO:0009607,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0043207,GO:0044403,GO:0044419,GO:0044464,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0071944,GO:0075136,GO:0075139 3.6.1.31 ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - PRA-PH GGPLMPOG_01195 1680.BADO_0842 9.16e-137 389.0 COG0036@1|root,COG0036@2|Bacteria,2GJZ9@201174|Actinobacteria,4CYX0@85004|Bifidobacteriales 201174|Actinobacteria G Ribulose-phosphate 3-epimerase rpe GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim GGPLMPOG_01196 566552.BIFCAT_00707 2.39e-231 638.0 COG0682@1|root,COG0682@2|Bacteria,2GKSS@201174|Actinobacteria,4CYV8@85004|Bifidobacteriales 201174|Actinobacteria M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - - - - - - - - - - LGT GGPLMPOG_01197 547043.BIFPSEUDO_03756 2.25e-207 573.0 COG0159@1|root,COG0159@2|Bacteria,2GN6T@201174|Actinobacteria,4D0A3@85004|Bifidobacteriales 201174|Actinobacteria E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate trpA GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - Trp_syntA GGPLMPOG_01198 547043.BIFPSEUDO_03757 0.0 1368.0 COG0133@1|root,COG0134@1|root,COG0133@2|Bacteria,COG0134@2|Bacteria,2GM7Z@201174|Actinobacteria,4CZJW@85004|Bifidobacteriales 201174|Actinobacteria E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine trpB GO:0000162,GO:0003674,GO:0003824,GO:0004834,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - IGPS,PALP GGPLMPOG_01199 547043.BIFPSEUDO_03758 0.0 1023.0 COG0147@1|root,COG0147@2|Bacteria,2GKJT@201174|Actinobacteria,4CZHW@85004|Bifidobacteriales 201174|Actinobacteria E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia trpE - 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind GGPLMPOG_01200 547043.BIFPSEUDO_03759 1.12e-95 278.0 COG0139@1|root,COG0139@2|Bacteria,2IKKU@201174|Actinobacteria,4D0WW@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP hisI GO:0008150,GO:0040007 3.5.4.19,3.6.1.31 ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037 RC00002,RC01055 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv1606 PRA-CH GGPLMPOG_01201 547043.BIFPSEUDO_03760 2.68e-176 492.0 COG0107@1|root,COG0107@2|Bacteria,2GIRP@201174|Actinobacteria,4CZ8Z@85004|Bifidobacteriales 201174|Actinobacteria E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit hisF GO:0000107,GO:0003674,GO:0003824,GO:0008150,GO:0016740,GO:0016757,GO:0016763,GO:0040007 4.1.3.27 ko:K01657,ko:K02500 ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023,M00026 R00985,R00986,R04558 RC00010,RC01190,RC01943,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth GGPLMPOG_01202 547043.BIFPSEUDO_03761 1.12e-287 785.0 COG0820@1|root,COG0820@2|Bacteria,2GJ48@201174|Actinobacteria,4CZG2@85004|Bifidobacteriales 201174|Actinobacteria J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs rlmN GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 ko:K06941 - - - - ko00000,ko01000,ko03009 - - - Radical_SAM GGPLMPOG_01203 547043.BIFPSEUDO_03762 5.62e-228 629.0 COG0575@1|root,COG0575@2|Bacteria,2I7ZA@201174|Actinobacteria,4CYZM@85004|Bifidobacteriales 201174|Actinobacteria I Cytidylyltransferase family cdsA - 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_1 GGPLMPOG_01204 547043.BIFPSEUDO_03763 4.41e-119 341.0 COG0233@1|root,COG0233@2|Bacteria,2GJ9J@201174|Actinobacteria,4CYTF@85004|Bifidobacteriales 201174|Actinobacteria J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another frr GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02838 - - - - ko00000,ko03012 - - - RRF GGPLMPOG_01205 547043.BIFPSEUDO_03764 2.04e-172 481.0 COG0528@1|root,COG0528@2|Bacteria,2GKWQ@201174|Actinobacteria,4CZEK@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the reversible phosphorylation of UMP to UDP pyrH GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - - AA_kinase GGPLMPOG_01207 547043.BIFPSEUDO_03766 6.23e-184 513.0 COG0264@1|root,COG0264@2|Bacteria,2GK4M@201174|Actinobacteria,4CYVQ@85004|Bifidobacteriales 201174|Actinobacteria J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS GGPLMPOG_01208 547043.BIFPSEUDO_03767 7.95e-183 510.0 COG0052@1|root,COG0052@2|Bacteria,2GMYC@201174|Actinobacteria,4CZ96@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the universal ribosomal protein uS2 family rpsB GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02967 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S2 GGPLMPOG_01209 78346.BRUM_0998 1.22e-107 310.0 COG0242@1|root,COG0242@2|Bacteria,2GJ87@201174|Actinobacteria,4CZ63@85004|Bifidobacteriales 201174|Actinobacteria J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def - 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase GGPLMPOG_01210 547043.BIFPSEUDO_03769 0.0 1306.0 COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4CYVD@85004|Bifidobacteriales 201174|Actinobacteria I long-chain-fatty acid CoA ligase fadD3 - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding GGPLMPOG_01211 547043.BIFPSEUDO_03770 1.25e-157 441.0 2BGJW@1|root,32AI7@2|Bacteria,2IR97@201174|Actinobacteria,4D19G@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01213 547043.BIFPSEUDO_03772 1.67e-241 664.0 COG0462@1|root,COG0462@2|Bacteria,2GJ9S@201174|Actinobacteria,4CYRD@85004|Bifidobacteriales 201174|Actinobacteria F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006015,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046390,GO:0046391,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901576 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran_N GGPLMPOG_01214 547043.BIFPSEUDO_03773 1.1e-180 502.0 COG1057@1|root,COG1057@2|Bacteria,2GMFZ@201174|Actinobacteria,4CZ82@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) nadD GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 ko:K00969 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like GGPLMPOG_01215 547043.BIFPSEUDO_03774 5.54e-131 372.0 2A13J@1|root,30P9F@2|Bacteria,2GKGD@201174|Actinobacteria,4D0QR@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01216 547043.BIFPSEUDO_03775 5.01e-311 848.0 COG0014@1|root,COG0014@2|Bacteria,2GISA@201174|Actinobacteria,4CZ2H@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate proA GO:0003674,GO:0003824,GO:0004350,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016620,GO:0016903,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv2427c Aldedh GGPLMPOG_01217 547043.BIFPSEUDO_03776 0.0 868.0 COG0112@1|root,COG0112@2|Bacteria,2GK7U@201174|Actinobacteria,4CZBV@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA GO:0001505,GO:0003674,GO:0003824,GO:0004372,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006544,GO:0006563,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009069,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016742,GO:0017144,GO:0019752,GO:0019842,GO:0020012,GO:0030170,GO:0030312,GO:0030682,GO:0036094,GO:0042133,GO:0042783,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044464,GO:0046983,GO:0048037,GO:0050662,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0065008,GO:0070279,GO:0071704,GO:0071944,GO:0075136,GO:0097159,GO:1901363,GO:1901564,GO:1901605 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT GGPLMPOG_01218 547043.BIFPSEUDO_03778 0.0 978.0 COG0498@1|root,COG0498@2|Bacteria,2GIRY@201174|Actinobacteria,4CYS0@85004|Bifidobacteriales 201174|Actinobacteria E Threonine synthase N terminus thrC - 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_synth_N GGPLMPOG_01219 1680.BADO_0952 2.06e-297 813.0 COG0477@1|root,COG2814@2|Bacteria,2I8HS@201174|Actinobacteria,4CZ4M@85004|Bifidobacteriales 201174|Actinobacteria EGP Transporter major facilitator family protein - - - - - - - - - - - - MFS_1 GGPLMPOG_01220 1680.BADO_0953 6.3e-140 394.0 COG0560@1|root,COG0560@2|Bacteria,2GMVR@201174|Actinobacteria,4D0CF@85004|Bifidobacteriales 201174|Actinobacteria E haloacid dehalogenase-like hydrolase - - - - - - - - - - - - HAD GGPLMPOG_01221 1680.BADO_0954 1.96e-222 612.0 COG3177@1|root,COG3177@2|Bacteria,2ICFW@201174|Actinobacteria,4D07M@85004|Bifidobacteriales 201174|Actinobacteria G Fic/DOC family - - - - - - - - - - - - Fic,HTH_26 GGPLMPOG_01222 566552.BIFCAT_00680 4.53e-181 502.0 2ENA9@1|root,33FXZ@2|Bacteria,2IHCR@201174|Actinobacteria,4CZCJ@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01223 566552.BIFCAT_00679 9.96e-209 578.0 COG1028@1|root,COG1028@2|Bacteria,2GJGM@201174|Actinobacteria,4CZMJ@85004|Bifidobacteriales 201174|Actinobacteria IQ Enoyl-(Acyl carrier protein) reductase - - 1.1.1.127 ko:K00065 ko00040,map00040 - R01542 RC00089 ko00000,ko00001,ko01000 - - - adh_short_C2 GGPLMPOG_01224 547043.BIFPSEUDO_03785 3.09e-215 594.0 COG0388@1|root,COG0388@2|Bacteria,2HZIM@201174|Actinobacteria,4D0K3@85004|Bifidobacteriales 201174|Actinobacteria S Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source - - - - - - - - - - - - CN_hydrolase GGPLMPOG_01225 547043.BIFPSEUDO_03786 2.43e-100 291.0 COG0388@1|root,COG0388@2|Bacteria,2HZIM@201174|Actinobacteria,4D0K3@85004|Bifidobacteriales 2|Bacteria S Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source - - 3.4.13.22 ko:K08641,ko:K11206 ko01502,ko02020,map01502,map02020 M00651 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 - - - CN_hydrolase,Peptidase_M15 GGPLMPOG_01227 1680.BADO_0958 1.5e-118 339.0 COG1225@1|root,COG1225@2|Bacteria,2IHZ6@201174|Actinobacteria,4D0PN@85004|Bifidobacteriales 201174|Actinobacteria O Redoxin bcp - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA GGPLMPOG_01228 566552.BIFCAT_00671 0.000284 44.7 COG3467@1|root,COG3467@2|Bacteria,2IGUA@201174|Actinobacteria,4D0SF@85004|Bifidobacteriales 201174|Actinobacteria S Pyridoxamine 5'-phosphate oxidase - - - ko:K07005 - - - - ko00000 - - - Pyridox_ox_2 GGPLMPOG_01229 1680.BADO_0967 3.11e-124 354.0 COG3467@1|root,COG3467@2|Bacteria,2IGUA@201174|Actinobacteria,4D0SF@85004|Bifidobacteriales 201174|Actinobacteria S Pyridoxamine 5'-phosphate oxidase - - - ko:K07005 - - - - ko00000 - - - Pyridox_ox_2 GGPLMPOG_01230 547043.BIFPSEUDO_03792 0.0 1249.0 2DBBJ@1|root,2Z889@2|Bacteria,2GKDX@201174|Actinobacteria,4CZGI@85004|Bifidobacteriales 201174|Actinobacteria S Histidine phosphatase superfamily (branch 2) - - - - - - - - - - - - His_Phos_2 GGPLMPOG_01231 547043.BIFPSEUDO_03793 9.32e-59 181.0 COG2801@1|root,COG2801@2|Bacteria 2|Bacteria L transposition - - - - - - - - - - - - HTH_21,HTH_Tnp_1,rve,rve_2 GGPLMPOG_01232 1680.BADO_0968 2.66e-31 115.0 COG2421@1|root,COG2421@2|Bacteria,2HQSF@201174|Actinobacteria,4D0CG@85004|Bifidobacteriales 201174|Actinobacteria C Acetamidase/Formamidase family - - - - - - - - - - - - FmdA_AmdA GGPLMPOG_01233 547043.BIFPSEUDO_03797 5.29e-78 233.0 COG1725@1|root,COG1725@2|Bacteria,2IQEW@201174|Actinobacteria,4D152@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn_helix gluconate operon transcriptional repressor - - - ko:K07979 - - - - ko00000,ko03000 - - - GntR GGPLMPOG_01234 547043.BIFPSEUDO_03798 1.95e-221 610.0 COG1131@1|root,COG1131@2|Bacteria,2GRE8@201174|Actinobacteria,4CZBH@85004|Bifidobacteriales 201174|Actinobacteria V ATPases associated with a variety of cellular activities - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran GGPLMPOG_01235 547043.BIFPSEUDO_03799 9.11e-150 423.0 29XRE@1|root,30JH3@2|Bacteria,2IJCR@201174|Actinobacteria,4D0VP@85004|Bifidobacteriales 201174|Actinobacteria S ABC-2 family transporter protein - - - - - - - - - - - - ABC2_membrane_5 GGPLMPOG_01236 547043.BIFPSEUDO_03800 4.87e-156 437.0 COG0637@1|root,COG0637@2|Bacteria,2I362@201174|Actinobacteria,4CZ8D@85004|Bifidobacteriales 201174|Actinobacteria S Haloacid dehalogenase-like hydrolase - - - - - - - - - - - - HAD_2 GGPLMPOG_01237 547043.BIFPSEUDO_03801 0.0 1041.0 COG0497@1|root,COG0497@2|Bacteria,2GIVG@201174|Actinobacteria,4CYYF@85004|Bifidobacteriales 201174|Actinobacteria L May be involved in recombinational repair of damaged DNA recN GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - ko:K03631 - - - - ko00000,ko03400 - - - AAA_23,SMC_N GGPLMPOG_01238 547043.BIFPSEUDO_03802 2.71e-228 630.0 COG0061@1|root,COG0061@2|Bacteria,2GKM2@201174|Actinobacteria,4CYZ0@85004|Bifidobacteriales 201174|Actinobacteria H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006797,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - - NAD_kinase GGPLMPOG_01239 547043.BIFPSEUDO_03803 0.0 960.0 COG0168@1|root,COG0168@2|Bacteria,2GKKS@201174|Actinobacteria,4CZH7@85004|Bifidobacteriales 201174|Actinobacteria P Cation transport protein trkH - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH GGPLMPOG_01240 547043.BIFPSEUDO_03804 1.25e-150 424.0 COG0569@1|root,COG0569@2|Bacteria,2IA09@201174|Actinobacteria,4CZVT@85004|Bifidobacteriales 201174|Actinobacteria P TrkA-N domain trkA - - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N GGPLMPOG_01241 547043.BIFPSEUDO_03805 5.6e-172 481.0 COG1189@1|root,COG1189@2|Bacteria,2GJVT@201174|Actinobacteria,4CZSS@85004|Bifidobacteriales 201174|Actinobacteria J Ribosomal RNA large subunit methyltransferase J tlyA GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.226,2.1.1.227 ko:K06442 - - - - ko00000,ko01000,ko03009 - - - FtsJ,S4 GGPLMPOG_01242 547043.BIFPSEUDO_03806 7.6e-246 675.0 COG0647@1|root,COG0647@2|Bacteria,2GK7V@201174|Actinobacteria,4CZ1Z@85004|Bifidobacteriales 201174|Actinobacteria G Haloacid dehalogenase-like hydrolase - - - - - - - - - - - - Hydrolase_6,Hydrolase_like GGPLMPOG_01243 1680.BADO_0978 1.28e-215 618.0 COG0457@1|root,COG0457@2|Bacteria,2GKX5@201174|Actinobacteria,4CYXN@85004|Bifidobacteriales 201174|Actinobacteria L Tetratricopeptide repeat - - - - - - - - - - - - TPR_19 GGPLMPOG_01244 547043.BIFPSEUDO_03809 0.0 863.0 COG0162@1|root,COG0162@2|Bacteria,2GJPR@201174|Actinobacteria,4CZKG@85004|Bifidobacteriales 201174|Actinobacteria J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0030312,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b GGPLMPOG_01245 547043.BIFPSEUDO_03810 0.0 1222.0 COG4905@1|root,COG5523@1|root,COG4905@2|Bacteria,COG5523@2|Bacteria,2IB0C@201174|Actinobacteria,4D0E9@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF975) - - - - - - - - - - - - ABC_trans_CmpB,DUF975 GGPLMPOG_01246 547043.BIFPSEUDO_03811 1.01e-181 506.0 COG4905@1|root,COG4905@2|Bacteria,2IA3M@201174|Actinobacteria,4CZY7@85004|Bifidobacteriales 201174|Actinobacteria S Putative ABC-transporter type IV - - - - - - - - - - - - ABC_trans_CmpB GGPLMPOG_01247 547043.BIFPSEUDO_03812 4.08e-123 350.0 COG1418@1|root,COG1418@2|Bacteria,2IFXP@201174|Actinobacteria,4D0P2@85004|Bifidobacteriales 201174|Actinobacteria S Metal dependent phosphohydrolases with conserved 'HD' motif. - - - ko:K06950 - - - - ko00000 - - - HD GGPLMPOG_01248 547043.BIFPSEUDO_03813 0.0 961.0 COG0165@1|root,COG0165@2|Bacteria,2GJ2A@201174|Actinobacteria,4CZ50@85004|Bifidobacteriales 201174|Actinobacteria E argininosuccinate lyase argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0030312,GO:0040007,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ASL_C2,Lyase_1 GGPLMPOG_01249 547043.BIFPSEUDO_03814 4.33e-303 826.0 COG0137@1|root,COG0137@2|Bacteria,2GK96@201174|Actinobacteria,4CZ2R@85004|Bifidobacteriales 201174|Actinobacteria E Belongs to the argininosuccinate synthase family. Type 1 subfamily argG GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0071944,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 - - iNJ661.Rv1658 Arginosuc_synth GGPLMPOG_01250 547043.BIFPSEUDO_03815 5.46e-109 315.0 COG1438@1|root,COG1438@2|Bacteria,2GKA5@201174|Actinobacteria,4D0VM@85004|Bifidobacteriales 201174|Actinobacteria K Regulates arginine biosynthesis genes argR GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - ko:K03402 - - - - ko00000,ko03000 - - - Arg_repressor,Arg_repressor_C GGPLMPOG_01251 547043.BIFPSEUDO_03816 6.66e-235 645.0 COG0078@1|root,COG0078@2|Bacteria,2GJ6H@201174|Actinobacteria,4CZGN@85004|Bifidobacteriales 201174|Actinobacteria E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline argF GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0040007,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844 R01398 RC00096 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N GGPLMPOG_01252 566552.BIFCAT_00646 2.88e-307 838.0 COG4992@1|root,COG4992@2|Bacteria,2GKE9@201174|Actinobacteria,4CZGW@85004|Bifidobacteriales 201174|Actinobacteria E Aminotransferase class-III argD GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0008150,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 GGPLMPOG_01253 566552.BIFCAT_00645 8.32e-227 625.0 COG0548@1|root,COG0548@2|Bacteria,2GKDS@201174|Actinobacteria,4CYYX@85004|Bifidobacteriales 201174|Actinobacteria E Belongs to the acetylglutamate kinase family. ArgB subfamily argB GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0030312,GO:0031406,GO:0034618,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R02649 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase GGPLMPOG_01254 547043.BIFPSEUDO_03820 1.33e-273 749.0 COG1364@1|root,COG1364@2|Bacteria,2GIW0@201174|Actinobacteria,4CZQQ@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate argJ GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259,R02282 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - ArgJ GGPLMPOG_01255 547043.BIFPSEUDO_03821 1.58e-261 716.0 COG0002@1|root,COG0002@2|Bacteria,2GKQK@201174|Actinobacteria,4CZNC@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde argC GO:0000166,GO:0003674,GO:0005488,GO:0008150,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0048037,GO:0050661,GO:0050662,GO:0070401,GO:0097159,GO:1901265,GO:1901363 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC GGPLMPOG_01256 547043.BIFPSEUDO_03822 3.13e-147 417.0 2AHAX@1|root,317M8@2|Bacteria,2IPJ5@201174|Actinobacteria,4D11M@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01257 547043.BIFPSEUDO_03823 0.0 1734.0 COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,2GMFD@201174|Actinobacteria,4CYUM@85004|Bifidobacteriales 201174|Actinobacteria J Phenylalanyl-tRNA synthetase beta pheT GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind GGPLMPOG_01258 547043.BIFPSEUDO_03824 9.1e-261 714.0 COG0016@1|root,COG0016@2|Bacteria,2GJGG@201174|Actinobacteria,4CZ78@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Phe_tRNA-synt_N,tRNA-synt_2d GGPLMPOG_01259 547043.BIFPSEUDO_03825 7.78e-202 559.0 COG0566@1|root,COG0566@2|Bacteria,2GJI6@201174|Actinobacteria,4CYZQ@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family tsnR - - ko:K03437 - - - - ko00000,ko03016 - - - SpoU_methylase,SpoU_sub_bind GGPLMPOG_01260 547043.BIFPSEUDO_03828 1.28e-125 357.0 COG1611@1|root,COG1611@2|Bacteria,2GMM1@201174|Actinobacteria,4D031@85004|Bifidobacteriales 201174|Actinobacteria S Possible lysine decarboxylase yvdD - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Acetyltransf_1,Lysine_decarbox,NUDIX GGPLMPOG_01261 547043.BIFPSEUDO_03830 2.06e-25 95.1 2ENRX@1|root,33GD2@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - GGPLMPOG_01263 994573.T472_0211080 2.76e-15 71.6 COG1403@1|root,COG1403@2|Bacteria,1V7XZ@1239|Firmicutes,24JNG@186801|Clostridia,36IVP@31979|Clostridiaceae 186801|Clostridia L HNH endonuclease - - - ko:K07451 - - - - ko00000,ko01000,ko02048 - - - HNH GGPLMPOG_01264 547043.BIFPSEUDO_03833 2.27e-146 412.0 COG1573@1|root,COG1573@2|Bacteria,2IH02@201174|Actinobacteria,4D0XP@85004|Bifidobacteriales 201174|Actinobacteria L Uracil DNA glycosylase superfamily - - - - - - - - - - - - UDG GGPLMPOG_01265 585198.HMPREF0574_1856 1.52e-19 97.1 COG1002@1|root,COG1002@2|Bacteria,2IA5I@201174|Actinobacteria,4D518@85005|Actinomycetales 201174|Actinobacteria V Type II restriction enzyme, methylase subunits - - - - - - - - - - - - N6_Mtase GGPLMPOG_01266 547043.BIFPSEUDO_03836 0.0 971.0 COG0174@1|root,COG0174@2|Bacteria,2GMN1@201174|Actinobacteria,4CZNK@85004|Bifidobacteriales 201174|Actinobacteria E glutamine synthetase glnA GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N GGPLMPOG_01267 547043.BIFPSEUDO_03838 5.03e-183 509.0 2DBPK@1|root,2ZA9M@2|Bacteria,2I87Y@201174|Actinobacteria,4D302@85004|Bifidobacteriales 201174|Actinobacteria S Domain of unknown function (DUF4191) - - - - - - - - - - - - DUF4191 GGPLMPOG_01268 547043.BIFPSEUDO_03839 3.02e-313 858.0 COG1249@1|root,COG1249@2|Bacteria,2GIXY@201174|Actinobacteria,4CZEI@85004|Bifidobacteriales 201174|Actinobacteria C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family lpdA - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim GGPLMPOG_01269 1680.BADO_1002 1.66e-126 363.0 2AN86@1|root,31D67@2|Bacteria,2HWWU@201174|Actinobacteria,4CZZS@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF3043) - GO:0008150,GO:0009605,GO:0009607,GO:0020012,GO:0030682,GO:0042783,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136 - - - - - - - - - - DUF3043 GGPLMPOG_01270 547043.BIFPSEUDO_03841 0.0 871.0 COG0624@1|root,COG0624@2|Bacteria,2GM84@201174|Actinobacteria,4CYZT@85004|Bifidobacteriales 201174|Actinobacteria E Peptidase dimerisation domain argE - - - - - - - - - - - M20_dimer,Peptidase_M20 GGPLMPOG_01271 566552.BIFCAT_00622 1.27e-186 520.0 COG0619@1|root,COG0619@2|Bacteria,2IDC9@201174|Actinobacteria,4CZM8@85004|Bifidobacteriales 201174|Actinobacteria P Cobalt transport protein ykoC - - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - CbiQ GGPLMPOG_01272 566552.BIFCAT_00621 0.0 912.0 COG1122@1|root,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria,4CYZ6@85004|Bifidobacteriales 201174|Actinobacteria P ATPases associated with a variety of cellular activities ykoD - - ko:K16785,ko:K16786,ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran,CbiQ GGPLMPOG_01273 1680.BADO_1006 1.87e-109 318.0 COG4721@1|root,COG4721@2|Bacteria,2IDAN@201174|Actinobacteria,4D00D@85004|Bifidobacteriales 201174|Actinobacteria S ABC-type cobalt transport system, permease component ykoE - - ko:K16925 - M00582 - - ko00000,ko00002,ko02000 3.A.1.30 - - ABC_cobalt GGPLMPOG_01274 547043.BIFPSEUDO_03847 6.47e-258 709.0 COG0489@1|root,COG0489@2|Bacteria,2GJUZ@201174|Actinobacteria,4CZDC@85004|Bifidobacteriales 201174|Actinobacteria D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP mrp GO:0008150,GO:0040007 - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - FeS_assembly_P,ParA GGPLMPOG_01275 547043.BIFPSEUDO_03848 0.0 1703.0 COG0272@1|root,COG0272@2|Bacteria,2GJUY@201174|Actinobacteria,4CZBC@85004|Bifidobacteriales 201174|Actinobacteria L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016874,GO:0016886,GO:0030312,GO:0033554,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2 GGPLMPOG_01276 566552.BIFCAT_00615 0.0 2040.0 COG0457@1|root,COG0457@2|Bacteria,2GWSR@201174|Actinobacteria,4CZ33@85004|Bifidobacteriales 201174|Actinobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_19 GGPLMPOG_01277 547043.BIFPSEUDO_03850 0.0 1354.0 COG1807@1|root,COG1807@2|Bacteria,2GNXR@201174|Actinobacteria,4CZXK@85004|Bifidobacteriales 201174|Actinobacteria M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - - GGPLMPOG_01278 547043.BIFPSEUDO_03851 0.0 1053.0 2A5FI@1|root,30U5H@2|Bacteria,2I8X3@201174|Actinobacteria,4D09F@85004|Bifidobacteriales 201174|Actinobacteria S Arylsulfotransferase Ig-like domain - - 2.8.2.22 ko:K01023 - - - - ko00000,ko01000 - - - Arylsulfotran_N,Arylsulfotrans GGPLMPOG_01279 547043.BIFPSEUDO_03852 3.66e-185 515.0 COG1122@1|root,COG1122@2|Bacteria,2I9PF@201174|Actinobacteria,4D04S@85004|Bifidobacteriales 201174|Actinobacteria P ATPases associated with a variety of cellular activities - - - ko:K16784 ko02010,map02010 M00581 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25.1 - - ABC_tran GGPLMPOG_01280 547043.BIFPSEUDO_03853 7.28e-275 753.0 COG0436@1|root,COG0436@2|Bacteria,2GNMB@201174|Actinobacteria,4CZ48@85004|Bifidobacteriales 201174|Actinobacteria E Aminotransferase class I and II - - - - - - - - - - - - Aminotran_1_2 GGPLMPOG_01281 566552.BIFCAT_00610 3.28e-181 504.0 COG1940@1|root,COG1940@2|Bacteria,2GJA0@201174|Actinobacteria,4CYR1@85004|Bifidobacteriales 201174|Actinobacteria GK ROK family ppgK - 2.7.1.2,2.7.1.63 ko:K00845,ko:K00886 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786,R02187,R02189 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - ROK GGPLMPOG_01282 566552.BIFCAT_00609 1.14e-254 697.0 COG1216@1|root,COG1216@2|Bacteria,2GMQQ@201174|Actinobacteria,4CZRJ@85004|Bifidobacteriales 201174|Actinobacteria S Glycosyltransferase, group 2 family protein - - - - - - - - - - - - Glycos_transf_2 GGPLMPOG_01284 566552.BIFCAT_00608 1.11e-188 523.0 COG0819@1|root,COG0819@2|Bacteria,2IA0S@201174|Actinobacteria,4CZUI@85004|Bifidobacteriales 201174|Actinobacteria K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway tenA - 3.5.99.2 ko:K03707 ko00730,ko01100,map00730,map01100 - R02133,R09993 RC00224,RC00652,RC02832 ko00000,ko00001,ko01000,ko03000 - - - TENA_THI-4 GGPLMPOG_01285 547043.BIFPSEUDO_03859 3.73e-63 193.0 COG1534@1|root,COG1534@2|Bacteria,2IKSS@201174|Actinobacteria,4D10K@85004|Bifidobacteriales 201174|Actinobacteria J CRS1_YhbY - - - ko:K07574 - - - - ko00000,ko03009 - - - CRS1_YhbY GGPLMPOG_01286 566552.BIFCAT_00605 0.0 1429.0 COG0619@1|root,COG1129@1|root,COG0619@2|Bacteria,COG1129@2|Bacteria,2I2G4@201174|Actinobacteria,4CZJE@85004|Bifidobacteriales 201174|Actinobacteria GP ABC transporter, ATP-binding protein - - - ko:K16785,ko:K16786,ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran,CbiQ GGPLMPOG_01287 547043.BIFPSEUDO_03861 2.28e-138 392.0 COG3601@1|root,COG3601@2|Bacteria,2IAX0@201174|Actinobacteria,4CZQD@85004|Bifidobacteriales 201174|Actinobacteria U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins - - - - - - - - - - - - ECF_trnsprt GGPLMPOG_01288 566552.BIFCAT_00603 0.0 2368.0 COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,2GISC@201174|Actinobacteria,4CZSD@85004|Bifidobacteriales 201174|Actinobacteria KL Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - Helicase_C,SNF2_N,SNF2_assoc,SWIM GGPLMPOG_01289 547043.BIFPSEUDO_03864 1.6e-53 168.0 COG3579@1|root,COG3579@2|Bacteria 2|Bacteria E homocysteine catabolic process pepC GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006508,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0009056,GO:0009063,GO:0009636,GO:0009987,GO:0016054,GO:0016787,GO:0019538,GO:0019752,GO:0042221,GO:0043170,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0050667,GO:0050896,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.4.22.40 ko:K01372 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C1_2 GGPLMPOG_01290 547043.BIFPSEUDO_03865 4.94e-149 422.0 COG1226@1|root,COG1226@2|Bacteria,2GKNF@201174|Actinobacteria,4CZUV@85004|Bifidobacteriales 201174|Actinobacteria U Ion channel - - - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans_2 GGPLMPOG_01291 547043.BIFPSEUDO_03866 1.58e-237 653.0 COG0111@1|root,COG0111@2|Bacteria,2GP09@201174|Actinobacteria,4CZUN@85004|Bifidobacteriales 201174|Actinobacteria EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - - - - - - - - - - 2-Hacid_dh,2-Hacid_dh_C GGPLMPOG_01292 566552.BIFCAT_00598 1.09e-109 315.0 COG1490@1|root,COG1490@2|Bacteria,2IKVR@201174|Actinobacteria,4D0VE@85004|Bifidobacteriales 201174|Actinobacteria J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality dtd GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - ko:K07560 - - - - ko00000,ko01000,ko03016 - - - Tyr_Deacylase GGPLMPOG_01293 566552.BIFCAT_00597 4.92e-157 441.0 COG1073@1|root,COG1073@2|Bacteria,2HZF3@201174|Actinobacteria,4D06X@85004|Bifidobacteriales 201174|Actinobacteria S alpha beta - - - - - - - - - - - - - GGPLMPOG_01294 78345.BMERY_0240 1.32e-39 131.0 2E37J@1|root,32Y79@2|Bacteria,2GR14@201174|Actinobacteria,4D1IM@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01295 398513.BBNG_00801 1.25e-238 655.0 COG4127@1|root,COG4127@2|Bacteria,2IBF0@201174|Actinobacteria,4D0HD@85004|Bifidobacteriales 201174|Actinobacteria L Restriction endonuclease - - - ko:K07448 - - - - ko00000,ko02048 - - - Mrr_cat GGPLMPOG_01296 1216362.B437_00080 7.43e-27 122.0 COG4928@1|root,COG4928@2|Bacteria,37BG8@32066|Fusobacteria 32066|Fusobacteria S KAP family P-loop domain - - - - - - - - - - - - KAP_NTPase GGPLMPOG_01298 216816.GS08_04870 0.0 2156.0 COG0553@1|root,COG0553@2|Bacteria,2GM2V@201174|Actinobacteria 201174|Actinobacteria L helicase - - - - - - - - - - - - Helicase_C,PLDc_2,SNF2_N GGPLMPOG_01299 216816.GS08_04865 1.53e-155 438.0 28XY7@1|root,2ZJU4@2|Bacteria,2GN31@201174|Actinobacteria,4CZQG@85004|Bifidobacteriales 201174|Actinobacteria S Domain of unknown function (DUF4391) - - - - - - - - - - - - DUF4391 GGPLMPOG_01300 216816.GS08_04860 7.39e-288 808.0 COG2189@1|root,COG2189@2|Bacteria,2I8FH@201174|Actinobacteria,4D1Q7@85004|Bifidobacteriales 201174|Actinobacteria L DNA methylase mod - 2.1.1.72 ko:K07316 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase GGPLMPOG_01301 216816.GS08_04855 0.0 2066.0 COG3587@1|root,COG3587@2|Bacteria,2GMAF@201174|Actinobacteria,4D201@85004|Bifidobacteriales 201174|Actinobacteria V Type III restriction enzyme, res subunit res - 3.1.21.5 ko:K01156 - - - - ko00000,ko01000,ko02048 - - - ResIII GGPLMPOG_01302 553973.CLOHYLEM_07548 3.3e-70 219.0 28NWJ@1|root,2ZBUE@2|Bacteria,1V240@1239|Firmicutes,25DUD@186801|Clostridia 186801|Clostridia S MTH538 TIR-like domain (DUF1863) - - - - - - - - - - - - DUF1863 GGPLMPOG_01303 566552.BIFCAT_00588 3.31e-163 462.0 28P3D@1|root,2ZBZ3@2|Bacteria,2GP4T@201174|Actinobacteria,4D0S7@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - EcsC GGPLMPOG_01304 1034345.CAEM01000035_gene647 5.44e-103 311.0 COG4823@1|root,COG4823@2|Bacteria,2H7Q8@201174|Actinobacteria,4CXRE@84998|Coriobacteriia 84998|Coriobacteriia V Abi-like protein - - - - - - - - - - - - Abi_2 GGPLMPOG_01306 547043.BIFPSEUDO_03885 6.44e-90 265.0 2APTZ@1|root,31EYD@2|Bacteria,2ICWI@201174|Actinobacteria,4D0N4@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01307 566552.BIFCAT_00586 1.53e-271 752.0 28IDI@1|root,2Z8FT@2|Bacteria,2I4VR@201174|Actinobacteria,4CZZH@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01308 566552.BIFCAT_00585 4.18e-191 530.0 COG4186@1|root,COG4186@2|Bacteria,2IRS9@201174|Actinobacteria,4D018@85004|Bifidobacteriales 201174|Actinobacteria S phosphoesterase or phosphohydrolase - - - - - - - - - - - - Metallophos,Metallophos_2 GGPLMPOG_01309 1435051.BMOU_0059 1.94e-54 178.0 COG0111@1|root,COG0111@2|Bacteria,2GP09@201174|Actinobacteria,4CZUN@85004|Bifidobacteriales 201174|Actinobacteria EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - - - - - - - - - - 2-Hacid_dh,2-Hacid_dh_C GGPLMPOG_01312 547043.BIFPSEUDO_03891 4.51e-171 486.0 COG4585@1|root,COG4585@2|Bacteria,2IJ42@201174|Actinobacteria,4D13Z@85004|Bifidobacteriales 201174|Actinobacteria T Histidine kinase - - 2.7.13.3 ko:K07675 ko02020,map02020 M00473 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HisKA_3 GGPLMPOG_01313 547043.BIFPSEUDO_03892 1.14e-156 439.0 COG2197@1|root,COG2197@2|Bacteria,2HRPE@201174|Actinobacteria,4D098@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg GGPLMPOG_01314 547043.BIFPSEUDO_03893 0.0 1076.0 COG0515@1|root,COG4403@1|root,COG0515@2|Bacteria,COG4403@2|Bacteria,2GMRN@201174|Actinobacteria,4D21S@85004|Bifidobacteriales 201174|Actinobacteria KLT Lanthionine synthetase C-like protein - - - - - - - - - - - - LANC_like,Pkinase GGPLMPOG_01315 547043.BIFPSEUDO_03895 1.34e-177 494.0 COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria 201174|Actinobacteria V ABC transporter - - 3.6.3.44 ko:K06147,ko:K18104 ko01501,ko02010,map01501,map02010 M00700 - - ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 3.A.1.106,3.A.1.109,3.A.1.117,3.A.1.123,3.A.1.21 - - ABC_membrane,ABC_tran GGPLMPOG_01316 547043.BIFPSEUDO_03896 3.02e-202 561.0 COG1132@1|root,COG1132@2|Bacteria,2HBFJ@201174|Actinobacteria 201174|Actinobacteria V ABC transporter transmembrane region - - 3.6.3.44 ko:K18104 ko01501,ko02010,map01501,map02010 M00700 - - ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 3.A.1.117,3.A.1.123 - - ABC_membrane GGPLMPOG_01317 547043.BIFPSEUDO_03897 4.22e-154 436.0 COG1651@1|root,COG1651@2|Bacteria,2GN3N@201174|Actinobacteria,4D0RC@85004|Bifidobacteriales 201174|Actinobacteria O Thioredoxin - - - - - - - - - - - - Thioredoxin_4 GGPLMPOG_01318 547043.BIFPSEUDO_03898 9.73e-165 461.0 COG1246@1|root,COG1246@2|Bacteria,2I61X@201174|Actinobacteria,4D2U1@85004|Bifidobacteriales 201174|Actinobacteria E Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - Acetyltransf_1 GGPLMPOG_01319 566552.BIFCAT_00581 8.14e-169 473.0 COG1434@1|root,COG1434@2|Bacteria,2GMGZ@201174|Actinobacteria,4D0BS@85004|Bifidobacteriales 201174|Actinobacteria S DUF218 domain - - - - - - - - - - - - DUF218 GGPLMPOG_01320 566552.BIFCAT_00580 1.4e-300 823.0 COG0544@1|root,COG0544@2|Bacteria,2GJIG@201174|Actinobacteria,4CZ6P@85004|Bifidobacteriales 201174|Actinobacteria D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N GGPLMPOG_01321 566552.BIFCAT_00579 4.49e-297 812.0 COG0349@1|root,COG0349@2|Bacteria,2GKNM@201174|Actinobacteria,4CYUV@85004|Bifidobacteriales 201174|Actinobacteria J 3'-5' exonuclease rnd - 3.1.13.5 ko:K03684 - - - - ko00000,ko01000,ko03016 - - - DNA_pol_A_exo1,HRDC GGPLMPOG_01322 547043.BIFPSEUDO_03903 3.3e-102 298.0 2B58P@1|root,31Y2Q@2|Bacteria,2HZMM@201174|Actinobacteria,4D0Y9@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF3000) - - - - - - - - - - - - DUF3000 GGPLMPOG_01323 547043.BIFPSEUDO_03905 1.76e-210 581.0 COG1180@1|root,COG1180@2|Bacteria,2GN2B@201174|Actinobacteria,4CZ5Y@85004|Bifidobacteriales 201174|Actinobacteria C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine pflA - 1.97.1.4 ko:K04069 - - R04710 - ko00000,ko01000 - - - Fer4_12,Radical_SAM GGPLMPOG_01324 547043.BIFPSEUDO_03906 0.0 1610.0 COG1882@1|root,COG1882@2|Bacteria,2GTTT@201174|Actinobacteria,4CZ59@85004|Bifidobacteriales 201174|Actinobacteria C Pyruvate formate lyase-like pflB - 2.3.1.54 ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 - R00212,R06987 RC00004,RC01181,RC02742,RC02833 ko00000,ko00001,ko01000 - - - Gly_radical,PFL-like GGPLMPOG_01325 547043.BIFPSEUDO_03907 1.28e-41 136.0 2EHMB@1|root,33BD3@2|Bacteria,2HZRX@201174|Actinobacteria,4D1G1@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01326 566552.BIFCAT_00573 0.0 1098.0 COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2GK2C@201174|Actinobacteria,4CZ14@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source nadE - 6.3.5.1 ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase,NAD_synthase GGPLMPOG_01327 547043.BIFPSEUDO_03909 1.58e-286 781.0 COG1473@1|root,COG1473@2|Bacteria,2GK05@201174|Actinobacteria,4CZC6@85004|Bifidobacteriales 201174|Actinobacteria S Peptidase dimerisation domain - - - - - - - - - - - - M20_dimer,Peptidase_M20 GGPLMPOG_01328 547043.BIFPSEUDO_03910 3.32e-200 553.0 COG0561@1|root,COG0561@2|Bacteria,2HZBH@201174|Actinobacteria,4CZIQ@85004|Bifidobacteriales 201174|Actinobacteria S Sucrose-6F-phosphate phosphohydrolase - - - - - - - - - - - - Hydrolase_3 GGPLMPOG_01329 547043.BIFPSEUDO_03911 9e-192 533.0 COG1464@1|root,COG1464@2|Bacteria,2GMNI@201174|Actinobacteria,4CZNB@85004|Bifidobacteriales 201174|Actinobacteria P NLPA lipoprotein metQ - - ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 GGPLMPOG_01330 547043.BIFPSEUDO_03912 4.13e-188 523.0 COG1135@1|root,COG1135@2|Bacteria,2GJ9P@201174|Actinobacteria,4CZYI@85004|Bifidobacteriales 201174|Actinobacteria P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system metN - - ko:K02071 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - ABC_tran,NIL GGPLMPOG_01331 547043.BIFPSEUDO_03913 1.59e-144 409.0 COG2011@1|root,COG2011@2|Bacteria,2GY65@201174|Actinobacteria,4CZWG@85004|Bifidobacteriales 201174|Actinobacteria P Binding-protein-dependent transport system inner membrane component metI - - ko:K02072 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - BPD_transp_1 GGPLMPOG_01332 547043.BIFPSEUDO_03914 2.16e-98 285.0 2ATF2@1|root,31IYI@2|Bacteria,2IIKG@201174|Actinobacteria,4D0ZG@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01335 216816.GS08_05975 1.34e-166 470.0 COG4823@1|root,COG4823@2|Bacteria,2HWAP@201174|Actinobacteria,4D0Z3@85004|Bifidobacteriales 201174|Actinobacteria V Abi-like protein - - - - - - - - - - - - Abi_2 GGPLMPOG_01336 216816.GS08_05975 7.95e-26 102.0 COG4823@1|root,COG4823@2|Bacteria,2HWAP@201174|Actinobacteria,4D0Z3@85004|Bifidobacteriales 201174|Actinobacteria V Abi-like protein - - - - - - - - - - - - Abi_2 GGPLMPOG_01337 547043.BIFPSEUDO_03180 1.21e-315 860.0 COG4279@1|root,COG4279@2|Bacteria,2GJ39@201174|Actinobacteria,4CZC0@85004|Bifidobacteriales 201174|Actinobacteria S zinc finger - - - - - - - - - - - - - GGPLMPOG_01338 547043.BIFPSEUDO_03178 3.52e-96 280.0 COG3428@1|root,COG3428@2|Bacteria,2IFD2@201174|Actinobacteria,4D0RX@85004|Bifidobacteriales 201174|Actinobacteria S Bacterial PH domain - - - - - - - - - - - - bPH_2 GGPLMPOG_01339 547043.BIFPSEUDO_03177 2.94e-99 288.0 29SSD@1|root,30DYB@2|Bacteria,2IJ1J@201174|Actinobacteria,4D0SG@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01340 1680.BADO_1669 0.0 1563.0 COG1061@1|root,COG3886@1|root,COG1061@2|Bacteria,COG3886@2|Bacteria,2GJ4Y@201174|Actinobacteria,4CZNN@85004|Bifidobacteriales 201174|Actinobacteria KL Domain of unknown function (DUF3427) - - - - - - - - - - - - DUF3427,Helicase_C,PLDc_2,ResIII GGPLMPOG_01341 78346.BRUM_1580 1.06e-16 79.0 COG1061@1|root,COG3886@1|root,COG1061@2|Bacteria,COG3886@2|Bacteria,2GJ4Y@201174|Actinobacteria,4CZNN@85004|Bifidobacteriales 201174|Actinobacteria KL Domain of unknown function (DUF3427) - - - - - - - - - - - - DUF3427,Helicase_C,PLDc_2,ResIII GGPLMPOG_01342 518635.BIFANG_02718 1.49e-77 233.0 COG0494@1|root,COG0494@2|Bacteria,2I2GY@201174|Actinobacteria,4D0UJ@85004|Bifidobacteriales 201174|Actinobacteria L NUDIX domain mutT - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX GGPLMPOG_01343 547043.BIFPSEUDO_03169 0.0 1165.0 COG0210@1|root,COG0210@2|Bacteria,2IA1B@201174|Actinobacteria,4D066@85004|Bifidobacteriales 201174|Actinobacteria L Psort location Cytoplasmic, score 8.87 - - 3.6.4.12 ko:K03658 - - - - ko00000,ko01000,ko03400 - - - UvrD-helicase,UvrD_C,zf-C4_Topoisom GGPLMPOG_01344 547043.BIFPSEUDO_03168 1.69e-235 648.0 COG0673@1|root,COG0673@2|Bacteria,2GKW0@201174|Actinobacteria,4CYXG@85004|Bifidobacteriales 201174|Actinobacteria S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C GGPLMPOG_01345 566552.BIFCAT_00327 1.57e-91 268.0 COG3727@1|root,COG3727@2|Bacteria,2IKPY@201174|Actinobacteria,4D0R6@85004|Bifidobacteriales 201174|Actinobacteria L May nick specific sequences that contain T G mispairs resulting from m5C-deamination vsr - - ko:K07458 - - - - ko00000,ko01000,ko03400 - - - Vsr GGPLMPOG_01346 566552.BIFCAT_00328 2.48e-295 805.0 COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,4CZQP@85004|Bifidobacteriales 201174|Actinobacteria E Aminotransferase class-V aspB - 2.6.1.1,2.6.1.2,2.6.1.66 ko:K00812,ko:K08969,ko:K14260 ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00034 R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052,R07396 RC00006,RC00008,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 GGPLMPOG_01347 547043.BIFPSEUDO_03163 4.54e-214 593.0 COG0248@1|root,COG0248@2|Bacteria,2GMME@201174|Actinobacteria,4CYW8@85004|Bifidobacteriales 201174|Actinobacteria FP Ppx/GppA phosphatase family ppx1 GO:0003674,GO:0003824,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - Ppx-GppA GGPLMPOG_01348 78346.BRUM_1572 1.41e-128 370.0 28XY7@1|root,2ZJU4@2|Bacteria,2GN31@201174|Actinobacteria,4CZQG@85004|Bifidobacteriales 201174|Actinobacteria S Domain of unknown function (DUF4391) tmp1 - - - - - - - - - - - DUF4391 GGPLMPOG_01350 1120945.ATUW01000001_gene1632 9.65e-56 183.0 COG1136@1|root,COG1136@2|Bacteria,2IT8D@201174|Actinobacteria,4D6CR@85005|Actinomycetales 201174|Actinobacteria V ATPases associated with a variety of cellular activities - - - - - - - - - - - - ABC_tran GGPLMPOG_01351 566552.BIFCAT_00332 4.12e-253 695.0 COG3568@1|root,COG3568@2|Bacteria,2I2GX@201174|Actinobacteria,4CYTX@85004|Bifidobacteriales 201174|Actinobacteria S Endonuclease/Exonuclease/phosphatase family - - - ko:K18353 ko01502,ko02020,map01502,map02020 M00651 - - ko00000,ko00001,ko00002,ko01504 - - - Exo_endo_phos GGPLMPOG_01353 566552.BIFCAT_00334 8.4e-56 174.0 COG1722@1|root,COG1722@2|Bacteria,2GR0U@201174|Actinobacteria,4D18C@85004|Bifidobacteriales 201174|Actinobacteria L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseB - 3.1.11.6 ko:K03602 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_S GGPLMPOG_01354 547043.BIFPSEUDO_03157 1.05e-311 848.0 COG1570@1|root,COG1570@2|Bacteria,2GJAS@201174|Actinobacteria,4CZU4@85004|Bifidobacteriales 201174|Actinobacteria L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 GGPLMPOG_01355 566552.BIFCAT_00336 0.0 1638.0 COG1328@1|root,COG1328@2|Bacteria,2GMGA@201174|Actinobacteria,4CYV3@85004|Bifidobacteriales 201174|Actinobacteria F Anaerobic ribonucleoside-triphosphate reductase nrdD - 1.1.98.6 ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000 - - - ATP-cone,NRDD GGPLMPOG_01356 547043.BIFPSEUDO_03155 7.49e-178 494.0 COG0602@1|root,COG0602@2|Bacteria,2H0HA@201174|Actinobacteria,4CYSC@85004|Bifidobacteriales 201174|Actinobacteria O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine nrdG - 1.97.1.4 ko:K04068 - - R04710 - ko00000,ko01000 - - - Fer4_12,Radical_SAM GGPLMPOG_01357 547043.BIFPSEUDO_03154 5.91e-199 551.0 COG1924@1|root,COG1924@2|Bacteria,2HI6K@201174|Actinobacteria,4CZN6@85004|Bifidobacteriales 201174|Actinobacteria I BadF/BadG/BcrA/BcrD ATPase family - - - - - - - - - - - - BcrAD_BadFG GGPLMPOG_01358 547043.BIFPSEUDO_03153 0.0 2566.0 COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,2I1VH@201174|Actinobacteria,4CZ6Y@85004|Bifidobacteriales 201174|Actinobacteria I CoA enzyme activase uncharacterised domain (DUF2229) hgdC - - - - - - - - - - - BcrAD_BadFG,DUF2229,HGD-D GGPLMPOG_01359 547043.BIFPSEUDO_03152 0.0 880.0 COG3572@1|root,COG3572@2|Bacteria,2GJPI@201174|Actinobacteria,4CYZP@85004|Bifidobacteriales 201174|Actinobacteria H Glutamate-cysteine ligase family 2(GCS2) egtA GO:0003674,GO:0003824,GO:0004357,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0044464,GO:0071944 6.3.2.2 ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv3704c GCS2 GGPLMPOG_01360 547043.BIFPSEUDO_03151 3.74e-155 434.0 COG1309@1|root,COG1309@2|Bacteria,2ICYK@201174|Actinobacteria,4CYZC@85004|Bifidobacteriales 201174|Actinobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N GGPLMPOG_01361 547043.BIFPSEUDO_03150 0.0 1440.0 COG1874@1|root,COG1874@2|Bacteria,2GK4P@201174|Actinobacteria,4CZKE@85004|Bifidobacteriales 201174|Actinobacteria G Beta-galactosidase trimerisation domain - - 3.2.1.23 ko:K12308 ko00052,map00052 - R01105 RC00452 ko00000,ko00001,ko01000 - - - Glyco_hydro_42,Glyco_hydro_42M GGPLMPOG_01362 547043.BIFPSEUDO_03148 5.95e-147 414.0 COG1309@1|root,COG1309@2|Bacteria,2ICY9@201174|Actinobacteria,4D0I5@85004|Bifidobacteriales 201174|Actinobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N GGPLMPOG_01363 547043.BIFPSEUDO_03147 2.19e-307 839.0 COG2211@1|root,COG2211@2|Bacteria,2GJZG@201174|Actinobacteria,4CZ93@85004|Bifidobacteriales 201174|Actinobacteria G Transporter major facilitator family protein - - - - - - - - - - - - MFS_1 GGPLMPOG_01364 547043.BIFPSEUDO_03145 0.0 944.0 COG5520@1|root,COG5520@2|Bacteria,2GMWN@201174|Actinobacteria,4CYYZ@85004|Bifidobacteriales 201174|Actinobacteria G Glycosyl hydrolase family 30 TIM-barrel domain - - 3.2.1.45 ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 - R01498 RC00059,RC00451 ko00000,ko00001,ko01000 - GH30 - CBM_6,FIVAR,Glyco_hydro_30,Glyco_hydro_30C GGPLMPOG_01365 547043.BIFPSEUDO_03143 1.66e-125 357.0 COG1309@1|root,COG1309@2|Bacteria,2IJJG@201174|Actinobacteria,4D100@85004|Bifidobacteriales 201174|Actinobacteria K transcriptional regulator - - - - - - - - - - - - TetR_N GGPLMPOG_01366 547043.BIFPSEUDO_03142 2.04e-283 777.0 COG2271@1|root,COG2271@2|Bacteria,2I2GW@201174|Actinobacteria,4D2V8@85004|Bifidobacteriales 201174|Actinobacteria G MFS/sugar transport protein - - - - - - - - - - - - MFS_1 GGPLMPOG_01367 547043.BIFPSEUDO_03141 0.0 1086.0 COG3534@1|root,COG3534@2|Bacteria,2GMAK@201174|Actinobacteria,4CZS3@85004|Bifidobacteriales 201174|Actinobacteria G Alpha-L-arabinofuranosidase C-terminus - - 3.2.1.55 ko:K01209 ko00520,map00520 - R01762 - ko00000,ko00001,ko01000 - GH51 - Alpha-L-AF_C GGPLMPOG_01368 547043.BIFPSEUDO_03140 0.0 861.0 COG2730@1|root,COG2730@2|Bacteria,2I8WH@201174|Actinobacteria,4CZV7@85004|Bifidobacteriales 201174|Actinobacteria G Belongs to the glycosyl hydrolase 5 (cellulase A) family - - 3.2.1.4,3.2.1.58 ko:K01179,ko:K01210 ko00500,ko01100,map00500,map01100 - R00308,R03115,R06200,R11307,R11308 RC00467 ko00000,ko00001,ko01000 - GH5,GH9 - Cellulase GGPLMPOG_01369 547043.BIFPSEUDO_03139 0.0 1172.0 COG3507@1|root,COG3507@2|Bacteria,2GIW3@201174|Actinobacteria,4D037@85004|Bifidobacteriales 201174|Actinobacteria G Glycosyl hydrolases family 43 - - 3.2.1.37 ko:K01198 ko00520,ko01100,map00520,map01100 - R01433 RC00467 ko00000,ko00001,ko01000 - GH43 - Glyco_hydro_43 GGPLMPOG_01370 547043.BIFPSEUDO_03138 1.13e-312 850.0 COG2730@1|root,COG2730@2|Bacteria,2I8WH@201174|Actinobacteria,4CZV7@85004|Bifidobacteriales 201174|Actinobacteria G Belongs to the glycosyl hydrolase 5 (cellulase A) family - - 3.2.1.4,3.2.1.58 ko:K01179,ko:K01210 ko00500,ko01100,map00500,map01100 - R00308,R03115,R06200,R11307,R11308 RC00467 ko00000,ko00001,ko01000 - GH5,GH9 - Cellulase GGPLMPOG_01371 547043.BIFPSEUDO_03137 1.51e-143 404.0 COG1309@1|root,COG1309@2|Bacteria,2ICYK@201174|Actinobacteria,4CYZC@85004|Bifidobacteriales 201174|Actinobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N GGPLMPOG_01372 547043.BIFPSEUDO_03136 1.37e-289 790.0 COG1181@1|root,COG1181@2|Bacteria,2I2GF@201174|Actinobacteria,4D0FN@85004|Bifidobacteriales 201174|Actinobacteria M Belongs to the D-alanine--D-alanine ligase family - - - - - - - - - - - - - GGPLMPOG_01373 566552.BIFCAT_00356 5.06e-280 767.0 COG0477@1|root,COG2814@2|Bacteria,2IFA0@201174|Actinobacteria,4D0EP@85004|Bifidobacteriales 201174|Actinobacteria P Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 GGPLMPOG_01374 547043.BIFPSEUDO_03132 0.0 1560.0 COG1472@1|root,COG1472@2|Bacteria,2GJ5H@201174|Actinobacteria,4CZT6@85004|Bifidobacteriales 201174|Actinobacteria G Fibronectin type III-like domain bgl2 - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C GGPLMPOG_01375 547043.BIFPSEUDO_03131 1.25e-56 176.0 2AVW2@1|root,31MPW@2|Bacteria,2ING7@201174|Actinobacteria,4D15R@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01376 547043.BIFPSEUDO_03130 2.42e-281 769.0 COG1929@1|root,COG1929@2|Bacteria,2GKHX@201174|Actinobacteria,4CZRH@85004|Bifidobacteriales 201174|Actinobacteria G Belongs to the glycerate kinase type-1 family glxK - 2.7.1.165 ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 - R08572 RC00002,RC00428 ko00000,ko00001,ko01000 - - - Gly_kinase GGPLMPOG_01377 547043.BIFPSEUDO_03129 4.84e-140 395.0 COG1309@1|root,COG1309@2|Bacteria,2I8DN@201174|Actinobacteria,4CZXN@85004|Bifidobacteriales 201174|Actinobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_C_6,TetR_N GGPLMPOG_01378 547043.BIFPSEUDO_03128 0.0 1489.0 COG1472@1|root,COG1472@2|Bacteria,2GJ5H@201174|Actinobacteria,4CZ2P@85004|Bifidobacteriales 201174|Actinobacteria G Glycosyl hydrolase family 3 N-terminal domain protein bglB - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C GGPLMPOG_01379 547043.BIFPSEUDO_03127 7.8e-133 381.0 COG1846@1|root,COG1846@2|Bacteria,2IIWT@201174|Actinobacteria,4D0WT@85004|Bifidobacteriales 201174|Actinobacteria K MarR family - - - - - - - - - - - - MarR,MarR_2 GGPLMPOG_01380 547043.BIFPSEUDO_03126 0.0 1126.0 COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4CZMX@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter, ATP-binding protein - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran GGPLMPOG_01381 566552.BIFCAT_00365 0.0 1306.0 COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4CZPJ@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter transmembrane region - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran GGPLMPOG_01382 547043.BIFPSEUDO_03122 6.91e-235 647.0 COG1609@1|root,COG1609@2|Bacteria,2H5ZG@201174|Actinobacteria,4CZ8A@85004|Bifidobacteriales 201174|Actinobacteria K Transcriptional regulator, LacI family - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 GGPLMPOG_01383 547043.BIFPSEUDO_03121 0.0 899.0 COG2211@1|root,COG2211@2|Bacteria,2HD4Y@201174|Actinobacteria,4CZRA@85004|Bifidobacteriales 201174|Actinobacteria G Psort location CytoplasmicMembrane, score 10.00 gph - - ko:K16209 - - - - ko00000,ko02000 2.A.2.2 - - MFS_2 GGPLMPOG_01384 547043.BIFPSEUDO_03120 0.0 2234.0 COG0060@1|root,COG0060@2|Bacteria,2GK9M@201174|Actinobacteria,4CYT7@85004|Bifidobacteriales 201174|Actinobacteria J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1 GGPLMPOG_01385 356829.BITS_0805 4.13e-215 646.0 COG1203@1|root,COG1203@2|Bacteria,2I266@201174|Actinobacteria,4CZU7@85004|Bifidobacteriales 201174|Actinobacteria L CRISPR-associated helicase Cas3 cas3 - - ko:K07012 - - - - ko00000,ko01000,ko02048 - - - Helicase_C GGPLMPOG_01386 356829.BITS_0806 3.24e-117 350.0 2EXKP@1|root,33QWM@2|Bacteria,2II2B@201174|Actinobacteria,4D0YQ@85004|Bifidobacteriales 201174|Actinobacteria - - - - - ko:K19133 - - - - ko00000,ko02048 - - - - GGPLMPOG_01387 356829.BITS_0807 0.0 880.0 COG1468@1|root,COG1518@1|root,COG1468@2|Bacteria,COG1518@2|Bacteria,2I8M0@201174|Actinobacteria,4CZYS@85004|Bifidobacteriales 201174|Actinobacteria L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette cas1 - - ko:K15342 - - - - ko00000,ko02048,ko03400 - - - Cas_Cas1,Cas_Cas4 GGPLMPOG_01388 754252.PFREUD_03680 2.07e-14 70.1 COG1343@1|root,COG1343@2|Bacteria,2GQ3K@201174|Actinobacteria 201174|Actinobacteria L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette cas2 - - ko:K09951 - - - - ko00000,ko02048 - - - CRISPR_Cas2 GGPLMPOG_01389 78346.BRUM_0314 3.88e-108 318.0 2C89M@1|root,332IE@2|Bacteria,2IPVJ@201174|Actinobacteria,4D133@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01390 547043.BIFPSEUDO_03107 3.92e-150 423.0 COG0400@1|root,COG0400@2|Bacteria,2GNIF@201174|Actinobacteria,4D0TH@85004|Bifidobacteriales 201174|Actinobacteria S Phospholipase/Carboxylesterase - - - ko:K06999 - - - - ko00000 - - - Abhydrolase_2 GGPLMPOG_01391 547043.BIFPSEUDO_03105 1.29e-304 829.0 COG1168@1|root,COG1168@2|Bacteria,2GJFQ@201174|Actinobacteria,4CZFH@85004|Bifidobacteriales 201174|Actinobacteria E Aminotransferase, class I II - - 4.4.1.8 ko:K00842,ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 GGPLMPOG_01392 547043.BIFPSEUDO_03104 7.22e-238 654.0 COG0583@1|root,COG0583@2|Bacteria,2GKT0@201174|Actinobacteria,4D04F@85004|Bifidobacteriales 201174|Actinobacteria K LysR substrate binding domain protein - - - - - - - - - - - - HTH_1,LysR_substrate GGPLMPOG_01393 547043.BIFPSEUDO_03102 1.54e-202 561.0 COG4667@1|root,COG4667@2|Bacteria,2I8R7@201174|Actinobacteria,4CZUH@85004|Bifidobacteriales 201174|Actinobacteria S Patatin-like phospholipase - - - - - - - - - - - - Patatin GGPLMPOG_01394 547043.BIFPSEUDO_03103 1.38e-226 625.0 COG1446@1|root,COG1446@2|Bacteria,2IDMF@201174|Actinobacteria,4D073@85004|Bifidobacteriales 201174|Actinobacteria E Asparaginase iaaA - 3.4.19.5 ko:K13051 - - - - ko00000,ko01000,ko01002 - - - Asparaginase_2 GGPLMPOG_01395 547043.BIFPSEUDO_03101 0.0 1082.0 COG4166@1|root,COG4166@2|Bacteria,2GIUH@201174|Actinobacteria,4CZFK@85004|Bifidobacteriales 201174|Actinobacteria E ABC transporter, substrate-binding protein, family 5 dppA - - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 GGPLMPOG_01396 547043.BIFPSEUDO_03100 4.32e-29 103.0 COG4667@1|root,COG4667@2|Bacteria 2|Bacteria S lipid catabolic process - - - ko:K07001 - - - - ko00000 - - - Patatin GGPLMPOG_01397 547043.BIFPSEUDO_03099 1.07e-186 519.0 COG0796@1|root,COG0796@2|Bacteria,2GN4I@201174|Actinobacteria,4CZ54@85004|Bifidobacteriales 201174|Actinobacteria M Provides the (R)-glutamate required for cell wall biosynthesis murI GO:0000270,GO:0003674,GO:0003824,GO:0004857,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008657,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010911,GO:0016020,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0030234,GO:0032780,GO:0034645,GO:0036361,GO:0042030,GO:0042546,GO:0043086,GO:0043170,GO:0043462,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0047661,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0072586,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:2000371,GO:2000372 5.1.1.3 ko:K01776 ko00471,ko01100,map00471,map01100 - R00260 RC00302 ko00000,ko00001,ko01000,ko01011 - - - Asp_Glu_race GGPLMPOG_01398 547043.BIFPSEUDO_03098 1.8e-216 597.0 COG0253@1|root,COG0253@2|Bacteria,2GKUD@201174|Actinobacteria,4CYQP@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine dapF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase GGPLMPOG_01399 547043.BIFPSEUDO_03097 1.82e-152 429.0 COG4243@1|root,COG4243@2|Bacteria,2GMVK@201174|Actinobacteria,4CZN1@85004|Bifidobacteriales 201174|Actinobacteria S Vitamin K epoxide reductase - - - - - - - - - - - - VKOR GGPLMPOG_01400 547043.BIFPSEUDO_03096 1.67e-221 610.0 COG0613@1|root,COG0613@2|Bacteria,2GNAP@201174|Actinobacteria,4CYQ5@85004|Bifidobacteriales 201174|Actinobacteria S DNA polymerase alpha chain like domain PPA1328 - 3.1.3.97,3.1.4.57 ko:K07053,ko:K20859 ko00440,map00440 - R00188,R10972,R10973,R11188 RC00078,RC00296 ko00000,ko00001,ko01000 - - - PHP GGPLMPOG_01401 547043.BIFPSEUDO_03095 4.61e-44 143.0 2AS45@1|root,31HGW@2|Bacteria,2HZSD@201174|Actinobacteria,4D1H9@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF3107) - - - - - - - - - - - - DUF3107 GGPLMPOG_01402 547043.BIFPSEUDO_03094 0.0 957.0 COG3173@1|root,COG3173@2|Bacteria,2I8R6@201174|Actinobacteria,4CYPR@85004|Bifidobacteriales 201174|Actinobacteria S Aminoglycoside phosphotransferase mphA - - - - - - - - - - - APH GGPLMPOG_01403 547043.BIFPSEUDO_03093 0.0 969.0 COG0210@1|root,COG0210@2|Bacteria,2GKRW@201174|Actinobacteria,4CZ3A@85004|Bifidobacteriales 201174|Actinobacteria L DNA helicase uvrD2 GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0006996,GO:0008094,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0040007,GO:0042623,GO:0043167,GO:0043169,GO:0046872,GO:0051276,GO:0071103,GO:0071840,GO:0140097 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - HRDC,UvrD-helicase,UvrD_C GGPLMPOG_01404 566552.BIFCAT_00396 0.0 1012.0 COG5282@1|root,COG5282@2|Bacteria,2GJ9K@201174|Actinobacteria,4CYU7@85004|Bifidobacteriales 201174|Actinobacteria S Zincin-like metallopeptidase - - - - - - - - - - - - Zincin_2 GGPLMPOG_01405 566552.BIFCAT_00397 9.98e-197 547.0 COG3480@1|root,COG3480@2|Bacteria,2GMFX@201174|Actinobacteria,4CYUP@85004|Bifidobacteriales 201174|Actinobacteria T Belongs to the peptidase S16 family sdrC - - ko:K07177 ko02024,map02024 - - - ko00000,ko00001,ko01002 - - - Lon_C GGPLMPOG_01406 547043.BIFPSEUDO_03090 3.68e-97 282.0 2B57P@1|root,31Y1M@2|Bacteria,2IFRB@201174|Actinobacteria,4D307@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF3052) - - - - - - - - - - - - DUF3052 GGPLMPOG_01408 547043.BIFPSEUDO_03087 0.0 893.0 COG3170@1|root,COG3170@2|Bacteria,2I2GE@201174|Actinobacteria,4CZDF@85004|Bifidobacteriales 201174|Actinobacteria NU Tfp pilus assembly protein FimV - - - - - - - - - - - - - GGPLMPOG_01409 547043.BIFPSEUDO_03086 2.8e-276 756.0 COG0743@1|root,COG0743@2|Bacteria,2GIRV@201174|Actinobacteria,4CZVC@85004|Bifidobacteriales 201174|Actinobacteria I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) dxr GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0050897,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv2870c DXPR_C,DXP_redisom_C,DXP_reductoisom GGPLMPOG_01410 547043.BIFPSEUDO_03085 1.93e-286 782.0 COG0821@1|root,COG0821@2|Bacteria,2GK2S@201174|Actinobacteria,4CYQB@85004|Bifidobacteriales 201174|Actinobacteria I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate ispG GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030312,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R08689,R10859 RC01486 ko00000,ko00001,ko00002,ko01000 - - - GcpE GGPLMPOG_01411 547043.BIFPSEUDO_03084 0.0 1100.0 COG0657@1|root,COG0657@2|Bacteria,2I2GD@201174|Actinobacteria,4CZUD@85004|Bifidobacteriales 201174|Actinobacteria I acetylesterase activity - - - - - - - - - - - - - GGPLMPOG_01412 547043.BIFPSEUDO_03083 4.14e-173 483.0 COG1381@1|root,COG1381@2|Bacteria,2GK81@201174|Actinobacteria,4CZCN@85004|Bifidobacteriales 201174|Actinobacteria L Involved in DNA repair and RecF pathway recombination recO GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N GGPLMPOG_01413 547043.BIFPSEUDO_03082 8.46e-197 544.0 COG0020@1|root,COG0020@2|Bacteria,2GIXF@201174|Actinobacteria,4CZAR@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids uppS GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008834,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0050347,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.86,2.5.1.88 ko:K00806,ko:K14215,ko:K21273 ko00900,ko01110,map00900,map01110 - R06447,R09244,R09731 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf GGPLMPOG_01414 547043.BIFPSEUDO_03081 3.27e-294 804.0 COG1957@1|root,COG1957@2|Bacteria,2I9SG@201174|Actinobacteria,4CZWE@85004|Bifidobacteriales 201174|Actinobacteria F nucleoside hydrolase - - - - - - - - - - - - IU_nuc_hydro GGPLMPOG_01415 547043.BIFPSEUDO_03080 4.99e-262 719.0 COG0715@1|root,COG0715@2|Bacteria,2HZ9T@201174|Actinobacteria,4CZ56@85004|Bifidobacteriales 201174|Actinobacteria P NMT1/THI5 like - - - - - - - - - - - - NMT1 GGPLMPOG_01416 547043.BIFPSEUDO_03079 4.99e-190 529.0 COG0600@1|root,COG0600@2|Bacteria,2GKKZ@201174|Actinobacteria,4CZ9Q@85004|Bifidobacteriales 201174|Actinobacteria P Binding-protein-dependent transport system inner membrane component - - - - - - - - - - - - BPD_transp_1 GGPLMPOG_01417 547043.BIFPSEUDO_03078 0.0 1084.0 COG1621@1|root,COG1621@2|Bacteria,2GJ9T@201174|Actinobacteria,4CZ8W@85004|Bifidobacteriales 201174|Actinobacteria G Belongs to the glycosyl hydrolase 32 family fosC - 3.2.1.26 ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00801,R00802,R02410,R03635,R03921,R06088 RC00028,RC00077 ko00000,ko00001,ko01000 - GH32 - Glyco_hydro_32C,Glyco_hydro_32N GGPLMPOG_01418 401473.BDP_1602 1.54e-307 839.0 COG2807@1|root,COG2807@2|Bacteria,2GJRD@201174|Actinobacteria,4CYTK@85004|Bifidobacteriales 201174|Actinobacteria P LacY proton/sugar symporter lacY - - ko:K02532 - - - - ko00000,ko02000 2.A.1.5 - - LacY_symp GGPLMPOG_01419 566552.BIFCAT_00412 1.86e-246 677.0 COG1609@1|root,COG1609@2|Bacteria,2GJY9@201174|Actinobacteria,4CYU5@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn _helix lactose operon repressor - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 GGPLMPOG_01420 547043.BIFPSEUDO_03074 3.37e-79 235.0 COG0011@1|root,COG0011@2|Bacteria,2IQ7E@201174|Actinobacteria,4D14E@85004|Bifidobacteriales 201174|Actinobacteria S Thiamine-binding protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Thiamine_BP GGPLMPOG_01421 547043.BIFPSEUDO_03073 4.31e-194 539.0 COG0351@1|root,COG0351@2|Bacteria,2GKZM@201174|Actinobacteria,4CYQA@85004|Bifidobacteriales 201174|Actinobacteria H Phosphomethylpyrimidine kinase thiD GO:0008150,GO:0040007 2.7.1.49,2.7.4.7 ko:K00941 ko00730,ko01100,map00730,map01100 M00127 R03471,R04509 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Phos_pyr_kin GGPLMPOG_01422 547043.BIFPSEUDO_03072 5.5e-171 478.0 COG0352@1|root,COG0352@2|Bacteria,2I2GC@201174|Actinobacteria,4D2V2@85004|Bifidobacteriales 201174|Actinobacteria H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) thiE - 2.5.1.3,2.7.1.49,2.7.4.7,4.1.99.17 ko:K03147,ko:K14153 ko00730,ko01100,map00730,map01100 M00127 R03223,R03471,R03472,R04509,R10712 RC00002,RC00017,RC00224,RC03251,RC03252,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - - Phos_pyr_kin,TMP-TENI GGPLMPOG_01423 547043.BIFPSEUDO_03071 4.66e-198 550.0 COG2145@1|root,COG2145@2|Bacteria,2IC73@201174|Actinobacteria,4CZU8@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) thiM - 2.7.1.50 ko:K00878 ko00730,ko01100,map00730,map01100 M00127 R04448 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HK GGPLMPOG_01424 547043.BIFPSEUDO_03070 0.0 1248.0 28N8A@1|root,2ZQTH@2|Bacteria,2ICHB@201174|Actinobacteria,4CZQ0@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01425 547043.BIFPSEUDO_03069 0.0 1187.0 COG2805@1|root,COG2805@2|Bacteria,2I9GT@201174|Actinobacteria,4D04P@85004|Bifidobacteriales 201174|Actinobacteria NU Type II/IV secretion system protein pilT - - ko:K02669 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE GGPLMPOG_01426 547043.BIFPSEUDO_03068 5.53e-282 780.0 COG2804@1|root,COG2804@2|Bacteria,2I8C2@201174|Actinobacteria,4CZG8@85004|Bifidobacteriales 201174|Actinobacteria NU Type II/IV secretion system protein pilB - - ko:K02652 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE,T2SSE_N GGPLMPOG_01427 547043.BIFPSEUDO_03060 7.08e-82 251.0 COG4972@1|root,COG4972@2|Bacteria,2IBNF@201174|Actinobacteria,4D02I@85004|Bifidobacteriales 201174|Actinobacteria NU Type IV pilus assembly protein PilM; pilM - - ko:K02662 - - - - ko00000,ko02035,ko02044 - - - PilM_2 GGPLMPOG_01428 547043.BIFPSEUDO_03059 2.81e-211 586.0 COG3166@1|root,COG3166@2|Bacteria,2IBVZ@201174|Actinobacteria,4D002@85004|Bifidobacteriales 201174|Actinobacteria NU PFAM Fimbrial assembly family protein - - - - - - - - - - - - - GGPLMPOG_01429 547043.BIFPSEUDO_03058 3.3e-137 389.0 2C85K@1|root,3482I@2|Bacteria,2HZWT@201174|Actinobacteria,4D004@85004|Bifidobacteriales 201174|Actinobacteria S Pilus assembly protein, PilO - - - ko:K02664 - - - - ko00000,ko02035,ko02044 - - - PilO GGPLMPOG_01430 547043.BIFPSEUDO_03057 0.0 1023.0 COG0423@1|root,COG0423@2|Bacteria,2GIT3@201174|Actinobacteria,4CYZU@85004|Bifidobacteriales 201174|Actinobacteria J Catalyzes the attachment of glycine to tRNA(Gly) glyQS GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 ko:K01880 ko00970,map00970 M00359,M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - HGTP_anticodon,tRNA-synt_2b GGPLMPOG_01431 547043.BIFPSEUDO_03056 1.31e-310 844.0 COG0042@1|root,COG0042@2|Bacteria,2GJ8I@201174|Actinobacteria,4CZFD@85004|Bifidobacteriales 201174|Actinobacteria J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines dus GO:0008150,GO:0010565,GO:0019216,GO:0019217,GO:0019222,GO:0031323,GO:0050789,GO:0050794,GO:0062012,GO:0065007,GO:0080090 - - - - - - - - - - Dus GGPLMPOG_01432 547043.BIFPSEUDO_03055 4.66e-279 765.0 COG0206@1|root,COG0206@2|Bacteria,2GJWC@201174|Actinobacteria,4CZ10@85004|Bifidobacteriales 201174|Actinobacteria D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity ftsZ GO:0000166,GO:0000287,GO:0000910,GO:0000921,GO:0000935,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022402,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032155,GO:0032185,GO:0032506,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0045787,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051258,GO:0051301,GO:0051726,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin GGPLMPOG_01433 547043.BIFPSEUDO_03054 5.84e-105 303.0 COG1799@1|root,COG1799@2|Bacteria,2GNVH@201174|Actinobacteria,4D0RJ@85004|Bifidobacteriales 201174|Actinobacteria D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA sepF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K09772 - - - - ko00000,ko03036 - - - SepF GGPLMPOG_01434 547043.BIFPSEUDO_03053 9.14e-55 171.0 COG0762@1|root,COG0762@2|Bacteria,2GQI1@201174|Actinobacteria,4D17B@85004|Bifidobacteriales 201174|Actinobacteria S YGGT family - - - ko:K02221 - - - - ko00000,ko02044 - - - YGGT GGPLMPOG_01435 547043.BIFPSEUDO_03052 1.38e-63 225.0 COG1566@1|root,COG1566@2|Bacteria,2I2G9@201174|Actinobacteria,4CZ5W@85004|Bifidobacteriales 201174|Actinobacteria V DivIVA protein - - - - - - - - - - - - DivIVA GGPLMPOG_01436 547043.BIFPSEUDO_03051 5.61e-121 346.0 COG0597@1|root,COG0597@2|Bacteria,2GKRX@201174|Actinobacteria,4D0WR@85004|Bifidobacteriales 201174|Actinobacteria MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins lspA - 3.4.23.36 ko:K03101 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_A8 GGPLMPOG_01437 547043.BIFPSEUDO_03050 3.52e-225 620.0 COG0564@1|root,COG0564@2|Bacteria,2GIY1@201174|Actinobacteria,4CYYR@85004|Bifidobacteriales 201174|Actinobacteria J Responsible for synthesis of pseudouridine from uracil rluD GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 GGPLMPOG_01438 547043.BIFPSEUDO_03049 0.0 2396.0 COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4CZKT@85004|Bifidobacteriales 201174|Actinobacteria L DNA polymerase III alpha subunit dnaE GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon GGPLMPOG_01439 547043.BIFPSEUDO_03048 0.0 895.0 COG0141@1|root,COG0141@2|Bacteria,2GKKA@201174|Actinobacteria,4CZ3E@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine hisD GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv1599 Histidinol_dh GGPLMPOG_01440 547043.BIFPSEUDO_03047 1.36e-287 785.0 COG0079@1|root,COG0079@2|Bacteria,2GJ9W@201174|Actinobacteria,4CZDT@85004|Bifidobacteriales 201174|Actinobacteria E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 GGPLMPOG_01441 547043.BIFPSEUDO_03046 4.56e-142 400.0 COG0131@1|root,COG0131@2|Bacteria,2GKMD@201174|Actinobacteria,4CZDD@85004|Bifidobacteriales 201174|Actinobacteria E Imidazoleglycerol-phosphate dehydratase hisB GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15,4.2.1.19 ko:K01089,ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03013,R03457 RC00017,RC00932 ko00000,ko00001,ko00002,ko01000 - - - IGPD GGPLMPOG_01442 547043.BIFPSEUDO_03045 1.15e-163 460.0 2EKCN@1|root,33E2Y@2|Bacteria,2GNIC@201174|Actinobacteria,4D0B5@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01443 547043.BIFPSEUDO_03044 1.77e-156 438.0 COG0118@1|root,COG0118@2|Bacteria,2GIYS@201174|Actinobacteria,4CZGA@85004|Bifidobacteriales 201174|Actinobacteria E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR hisH GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - GATase GGPLMPOG_01444 547043.BIFPSEUDO_03043 9.71e-167 466.0 COG0106@1|root,COG0106@2|Bacteria,2GJ4V@201174|Actinobacteria,4CZEA@85004|Bifidobacteriales 201174|Actinobacteria E Histidine biosynthesis protein hisA GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16,5.3.1.24 ko:K01814,ko:K01817 ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230 M00023,M00026 R03509,R04640 RC00945 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth GGPLMPOG_01445 547043.BIFPSEUDO_03042 0.0 915.0 COG0174@1|root,COG0174@2|Bacteria,2GJ2I@201174|Actinobacteria,4CZ0G@85004|Bifidobacteriales 201174|Actinobacteria E glutamine synthetase glnA2 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N GGPLMPOG_01446 547043.BIFPSEUDO_03041 1.68e-304 836.0 2AZXA@1|root,31S72@2|Bacteria,2GQBM@201174|Actinobacteria,4D1E0@85004|Bifidobacteriales 201174|Actinobacteria S Domain of unknown function (DUF5067) - - - - - - - - - - - - DUF5067 GGPLMPOG_01447 547043.BIFPSEUDO_03040 1.66e-185 520.0 COG5479@1|root,COG5479@2|Bacteria,2HYIN@201174|Actinobacteria,4CYU1@85004|Bifidobacteriales 201174|Actinobacteria M Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - - - - - - - - - - - GGPLMPOG_01448 547043.BIFPSEUDO_03039 6.09e-278 762.0 COG0477@1|root,COG2814@2|Bacteria,2GK8C@201174|Actinobacteria,4CZH1@85004|Bifidobacteriales 201174|Actinobacteria EGP Major Facilitator Superfamily - - - ko:K18567,ko:K19577 - - - - ko00000,ko02000 2.A.1.2.25,2.A.1.2.65 - - MFS_1,Sugar_tr GGPLMPOG_01449 547043.BIFPSEUDO_03038 2.51e-152 428.0 COG1136@1|root,COG1136@2|Bacteria,2ICH8@201174|Actinobacteria,4CZF8@85004|Bifidobacteriales 201174|Actinobacteria V ATPases associated with a variety of cellular activities - - - ko:K02003,ko:K09810 ko02010,map02010 M00255,M00258 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.125 - - ABC_tran GGPLMPOG_01451 1680.BADO_1176 5.66e-72 227.0 COG2197@1|root,COG2197@2|Bacteria,2GPC6@201174|Actinobacteria,4D16R@85004|Bifidobacteriales 201174|Actinobacteria T helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg GGPLMPOG_01452 547043.BIFPSEUDO_03037 4.54e-133 379.0 2F769@1|root,33ZMP@2|Bacteria,2IFMJ@201174|Actinobacteria,4D0UD@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01453 547043.BIFPSEUDO_03036 2.78e-251 690.0 COG3023@1|root,COG3023@2|Bacteria,2I9EN@201174|Actinobacteria,4D025@85004|Bifidobacteriales 201174|Actinobacteria V N-Acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - - GGPLMPOG_01454 547043.BIFPSEUDO_03035 4.61e-251 689.0 2C746@1|root,340R4@2|Bacteria,2I2G8@201174|Actinobacteria,4CZHI@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01455 547043.BIFPSEUDO_03034 0.0 2689.0 COG1643@1|root,COG1643@2|Bacteria,2GIWX@201174|Actinobacteria,4CZ3C@85004|Bifidobacteriales 201174|Actinobacteria L Helicase associated domain (HA2) Add an annotation hrpA - 3.6.4.13 ko:K03578 - - - - ko00000,ko01000 - - - AAA_19,DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind GGPLMPOG_01456 547043.BIFPSEUDO_03033 3.96e-144 408.0 COG2813@1|root,COG2813@2|Bacteria,2IFG7@201174|Actinobacteria,4CZP1@85004|Bifidobacteriales 201174|Actinobacteria J Ribosomal protein L11 methyltransferase (PrmA) rsmC - 2.1.1.172 ko:K00564 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - MTS GGPLMPOG_01457 547043.BIFPSEUDO_03032 0.0 934.0 COG2262@1|root,COG2262@2|Bacteria,2GK55@201174|Actinobacteria,4CZCB@85004|Bifidobacteriales 201174|Actinobacteria S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 GGPLMPOG_01458 547043.BIFPSEUDO_03031 3.25e-225 621.0 COG0039@1|root,COG0039@2|Bacteria,2GN5S@201174|Actinobacteria,4CYWK@85004|Bifidobacteriales 201174|Actinobacteria C Belongs to the LDH MDH superfamily. LDH family ldh - 1.1.1.27,1.1.1.37 ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 R00342,R00703,R01000,R03104,R07136 RC00031,RC00044 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N GGPLMPOG_01459 547043.BIFPSEUDO_03030 3.34e-192 536.0 COG1230@1|root,COG1230@2|Bacteria,2GMRZ@201174|Actinobacteria,4CZAB@85004|Bifidobacteriales 201174|Actinobacteria P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family czcD - - ko:K16264 - - - - ko00000,ko02000 2.A.4.1 - - Cation_efflux,ZT_dimer GGPLMPOG_01460 547043.BIFPSEUDO_03029 6.88e-170 474.0 COG1974@1|root,COG1974@2|Bacteria,2GMBN@201174|Actinobacteria,4CZ26@85004|Bifidobacteriales 201174|Actinobacteria K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair lexA - 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 GGPLMPOG_01461 547043.BIFPSEUDO_03028 8.85e-72 215.0 COG1388@1|root,COG1388@2|Bacteria,2HVH4@201174|Actinobacteria,4D1G8@85004|Bifidobacteriales 201174|Actinobacteria M Lysin motif - - - - - - - - - - - - LysM GGPLMPOG_01462 547043.BIFPSEUDO_03027 2.49e-110 317.0 COG1327@1|root,COG1327@2|Bacteria,2IHU9@201174|Actinobacteria,4D0P7@85004|Bifidobacteriales 201174|Actinobacteria K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes nrdR GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K07738 - - - - ko00000,ko03000 - - - ATP-cone GGPLMPOG_01463 1680.BADO_1162 1.19e-276 758.0 COG0111@1|root,COG0111@2|Bacteria,2GJGA@201174|Actinobacteria,4CYPT@85004|Bifidobacteriales 201174|Actinobacteria EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain serA - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C GGPLMPOG_01464 547043.BIFPSEUDO_03024 0.0 1469.0 COG3973@1|root,COG3973@2|Bacteria,2GK30@201174|Actinobacteria,4CYUF@85004|Bifidobacteriales 201174|Actinobacteria L DNA helicase - - - - - - - - - - - - AAA_19,UvrD_C_2,Viral_helicase1 GGPLMPOG_01465 547043.BIFPSEUDO_03023 9.51e-119 339.0 COG2001@1|root,COG2001@2|Bacteria,2IHUB@201174|Actinobacteria,4D0P1@85004|Bifidobacteriales 201174|Actinobacteria K Belongs to the MraZ family mraZ GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0040007,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - ko:K03925 - - - - ko00000 - - - MraZ GGPLMPOG_01466 547043.BIFPSEUDO_03022 4.05e-242 665.0 COG0275@1|root,COG0275@2|Bacteria,2GJGK@201174|Actinobacteria,4CYRM@85004|Bifidobacteriales 201174|Actinobacteria J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 GGPLMPOG_01467 1680.BADO_1158 1.47e-81 244.0 COG2919@1|root,COG2919@2|Bacteria,2IKUA@201174|Actinobacteria,4D109@85004|Bifidobacteriales 201174|Actinobacteria D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic - - - - - - - - - - - - - GGPLMPOG_01468 566552.BIFCAT_00450 0.0 1139.0 COG0768@1|root,COG0768@2|Bacteria,2GKHH@201174|Actinobacteria,4CYS8@85004|Bifidobacteriales 201174|Actinobacteria M Penicillin-binding protein, transpeptidase domain protein ftsI - 3.4.16.4 ko:K03587 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011,ko03036 - - - PBP_dimer,Transpeptidase GGPLMPOG_01469 547043.BIFPSEUDO_03019 2.91e-198 550.0 COG0769@1|root,COG0769@2|Bacteria,2GMZF@201174|Actinobacteria,4CYWT@85004|Bifidobacteriales 201174|Actinobacteria M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan - - - - - - - - - - - - - GGPLMPOG_01470 547043.BIFPSEUDO_03018 0.0 910.0 COG0770@1|root,COG0770@2|Bacteria,2GK0Y@201174|Actinobacteria,4CZ7U@85004|Bifidobacteriales 201174|Actinobacteria M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M GGPLMPOG_01471 547043.BIFPSEUDO_03017 1.38e-251 691.0 COG0472@1|root,COG0472@2|Bacteria,2GNEH@201174|Actinobacteria,4CYRX@85004|Bifidobacteriales 201174|Actinobacteria M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan mraY - 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 - R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 - - Glycos_transf_4,MraY_sig1 GGPLMPOG_01472 566552.BIFCAT_00454 0.0 875.0 COG0771@1|root,COG0771@2|Bacteria,2GJZA@201174|Actinobacteria,4CZKI@85004|Bifidobacteriales 201174|Actinobacteria M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - iNJ661.Rv2155c AlaDh_PNT_C,Mur_ligase_C,Mur_ligase_M GGPLMPOG_01473 566552.BIFCAT_00455 4.97e-259 714.0 COG0772@1|root,COG0772@2|Bacteria,2GKXP@201174|Actinobacteria,4CYPZ@85004|Bifidobacteriales 201174|Actinobacteria D Belongs to the SEDS family ftsW GO:0008150,GO:0040007 2.4.1.227 ko:K02563,ko:K03588 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011,ko02000,ko03036 2.A.103.1 GT28 - FTSW_RODA_SPOVE GGPLMPOG_01474 547043.BIFPSEUDO_03014 1.05e-273 751.0 COG0707@1|root,COG0707@2|Bacteria,2GJEM@201174|Actinobacteria,4CYQS@85004|Bifidobacteriales 201174|Actinobacteria M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG - 2.4.1.227,6.3.2.8 ko:K01924,ko:K02563 ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112 - R03193,R05032,R05662 RC00005,RC00049,RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - GT28 - Glyco_tran_28_C,Glyco_transf_28 GGPLMPOG_01475 547043.BIFPSEUDO_03013 0.0 936.0 COG0773@1|root,COG0773@2|Bacteria,2I2E7@201174|Actinobacteria,4CZ3B@85004|Bifidobacteriales 201174|Actinobacteria M Belongs to the MurCDEF family murC - 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M GGPLMPOG_01476 547043.BIFPSEUDO_03012 2.28e-180 509.0 COG1589@1|root,COG1589@2|Bacteria,2H4A4@201174|Actinobacteria,4D04A@85004|Bifidobacteriales 201174|Actinobacteria D Cell division protein FtsQ ftsQ GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944 - ko:K03589 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - FtsQ,POTRA_1 GGPLMPOG_01477 547043.BIFPSEUDO_03011 1.79e-315 857.0 COG2942@1|root,COG2942@2|Bacteria,2GMJ7@201174|Actinobacteria,4CZNY@85004|Bifidobacteriales 201174|Actinobacteria G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) - - - - - - - - - - - - GlcNAc_2-epim GGPLMPOG_01479 401473.BDP_1535 5.88e-278 764.0 COG3538@1|root,COG3538@2|Bacteria,2HHAF@201174|Actinobacteria,4CZYN@85004|Bifidobacteriales 201174|Actinobacteria S Metal-independent alpha-mannosidase (GH125) - - - ko:K09704 - - - - ko00000 - - - Glyco_hydro_125 GGPLMPOG_01480 547043.BIFPSEUDO_03009 6.73e-212 585.0 COG0524@1|root,COG0524@2|Bacteria,2HZB3@201174|Actinobacteria,4CZFC@85004|Bifidobacteriales 201174|Actinobacteria G pfkB family carbohydrate kinase - - 2.7.1.4 ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 - R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB GGPLMPOG_01481 547043.BIFPSEUDO_03008 6.36e-277 758.0 COG1940@1|root,COG1940@2|Bacteria,2GJ2S@201174|Actinobacteria,4CYV9@85004|Bifidobacteriales 201174|Actinobacteria GK ROK family - - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HTH_24,MarR_2,ROK GGPLMPOG_01482 547043.BIFPSEUDO_03007 0.0 1050.0 COG0747@1|root,COG0747@2|Bacteria,2GMAX@201174|Actinobacteria,4D2RC@85004|Bifidobacteriales 201174|Actinobacteria E Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 GGPLMPOG_01483 547043.BIFPSEUDO_03006 5.24e-239 659.0 COG0601@1|root,COG0601@2|Bacteria,2GJ2C@201174|Actinobacteria,4CZSV@85004|Bifidobacteriales 201174|Actinobacteria EP Binding-protein-dependent transport system inner membrane component dppB - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 GGPLMPOG_01484 547043.BIFPSEUDO_03005 6.04e-254 699.0 COG1173@1|root,COG1173@2|Bacteria,2GKAW@201174|Actinobacteria,4CZ2Y@85004|Bifidobacteriales 201174|Actinobacteria EP Binding-protein-dependent transport system inner membrane component dppC - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,OppC_N GGPLMPOG_01485 547043.BIFPSEUDO_03004 0.0 1080.0 COG1123@1|root,COG4172@2|Bacteria,2H3HY@201174|Actinobacteria,4CYU0@85004|Bifidobacteriales 201174|Actinobacteria P Belongs to the ABC transporter superfamily - - - ko:K02031,ko:K02032 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY GGPLMPOG_01486 547043.BIFPSEUDO_03003 2.62e-126 358.0 COG1051@1|root,COG1051@2|Bacteria,2IKKB@201174|Actinobacteria,4CZS4@85004|Bifidobacteriales 201174|Actinobacteria F NUDIX domain - - - - - - - - - - - - NUDIX GGPLMPOG_01487 566552.BIFCAT_00465 0.0 1073.0 COG0006@1|root,COG0006@2|Bacteria,2GM7D@201174|Actinobacteria,4CZIA@85004|Bifidobacteriales 201174|Actinobacteria E Aminopeptidase P, N-terminal domain pepP - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - AMP_N,Peptidase_M24 GGPLMPOG_01488 547043.BIFPSEUDO_03001 0.0 993.0 COG0285@1|root,COG0285@2|Bacteria,2GJP2@201174|Actinobacteria,4CZG9@85004|Bifidobacteriales 201174|Actinobacteria H Mur ligase middle domain folC GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv2447c Mur_ligase_C,Mur_ligase_M GGPLMPOG_01489 566552.BIFCAT_00468 1.35e-239 658.0 COG2348@1|root,COG2348@2|Bacteria,2GJUD@201174|Actinobacteria,4CZT9@85004|Bifidobacteriales 201174|Actinobacteria V Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_6,FemAB GGPLMPOG_01490 566552.BIFCAT_00469 0.0 999.0 COG0769@1|root,COG0769@2|Bacteria,2GIS2@201174|Actinobacteria,4CZAF@85004|Bifidobacteriales 201174|Actinobacteria M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE - 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M GGPLMPOG_01491 566552.BIFCAT_00470 2.73e-127 363.0 COG1595@1|root,COG1595@2|Bacteria,2GJ02@201174|Actinobacteria,4CZ09@85004|Bifidobacteriales 201174|Actinobacteria K Belongs to the sigma-70 factor family. ECF subfamily sigH GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 GGPLMPOG_01492 547043.BIFPSEUDO_02995 1.25e-49 157.0 29M53@1|root,3082I@2|Bacteria,2GTWX@201174|Actinobacteria,4D1EJ@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01493 566552.BIFCAT_00473 9.14e-239 655.0 COG2017@1|root,COG2017@2|Bacteria,2GJ0H@201174|Actinobacteria,4CYWN@85004|Bifidobacteriales 201174|Actinobacteria G Aldose 1-epimerase - - 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 - - - Aldose_epim GGPLMPOG_01494 566552.BIFCAT_00474 1.88e-219 609.0 COG0761@1|root,COG0761@2|Bacteria,2GIZ7@201174|Actinobacteria,4CZ8B@85004|Bifidobacteriales 201174|Actinobacteria IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis ispH - 1.17.7.4 ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05884,R08210 RC01137,RC01487 ko00000,ko00001,ko00002,ko01000 - - - LYTB GGPLMPOG_01495 547043.BIFPSEUDO_02992 8.17e-114 327.0 COG2606@1|root,COG2606@2|Bacteria,2IHS8@201174|Actinobacteria,4CZFI@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily ybaK - - ko:K03976 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit GGPLMPOG_01496 547043.BIFPSEUDO_02991 4.82e-254 696.0 COG0057@1|root,COG0057@2|Bacteria,2GJK4@201174|Actinobacteria,4CZ97@85004|Bifidobacteriales 201174|Actinobacteria G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gap - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N GGPLMPOG_01497 566552.BIFCAT_00477 2.3e-142 405.0 COG1564@1|root,COG1564@2|Bacteria,2HQZZ@201174|Actinobacteria,4CZBY@85004|Bifidobacteriales 201174|Actinobacteria H Thiamin pyrophosphokinase, vitamin B1 binding domain - - 2.7.6.2 ko:K00949 ko00730,ko01100,map00730,map01100 - R00619 RC00002,RC00017 ko00000,ko00001,ko01000 - - - TPK_B1_binding,TPK_catalytic GGPLMPOG_01498 547043.BIFPSEUDO_02988 1.86e-139 398.0 COG0290@1|root,COG0290@2|Bacteria,2GJGT@201174|Actinobacteria,4CZA3@85004|Bifidobacteriales 201174|Actinobacteria J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins infC GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - ko:K02520 - - - - ko00000,ko03012,ko03029 - - - IF3_C,IF3_N GGPLMPOG_01499 547043.BIFPSEUDO_02987 3.31e-35 120.0 COG0291@1|root,COG0291@2|Bacteria,2HZRM@201174|Actinobacteria,4D1EV@85004|Bifidobacteriales 201174|Actinobacteria J Ribosomal protein L35 rpmI - - ko:K02916 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L35p GGPLMPOG_01500 547043.BIFPSEUDO_02986 7.76e-81 240.0 COG0292@1|root,COG0292@2|Bacteria,2IHTN@201174|Actinobacteria,4D0QF@85004|Bifidobacteriales 201174|Actinobacteria J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit rplT GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016020,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0071944,GO:1990904 - ko:K02887 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L20 GGPLMPOG_01501 547043.BIFPSEUDO_02985 2.12e-224 619.0 COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4CZ69@85004|Bifidobacteriales 201174|Actinobacteria D recombinase XerD xerD GO:0008150,GO:0040007 - ko:K03733,ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase GGPLMPOG_01502 547043.BIFPSEUDO_02984 8.39e-196 543.0 COG1192@1|root,COG1192@2|Bacteria,2GJX3@201174|Actinobacteria,4CYV4@85004|Bifidobacteriales 201174|Actinobacteria D CobQ CobB MinD ParA nucleotide binding domain protein soj GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944 - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 GGPLMPOG_01503 547043.BIFPSEUDO_02983 6.41e-193 535.0 COG1051@1|root,COG1051@2|Bacteria,2GNMT@201174|Actinobacteria,4CZNZ@85004|Bifidobacteriales 201174|Actinobacteria F NUDIX hydrolase - - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX GGPLMPOG_01504 547043.BIFPSEUDO_02982 0.0 868.0 COG0477@1|root,COG0477@2|Bacteria,2HC9X@201174|Actinobacteria,4D2V1@85004|Bifidobacteriales 201174|Actinobacteria U Sugar (and other) transporter nanT - - ko:K03290,ko:K08178,ko:K08369 - - - - ko00000,ko02000 2.A.1,2.A.1.12 - - MFS_1,Sugar_tr GGPLMPOG_01505 547043.BIFPSEUDO_02981 0.0 1268.0 COG1217@1|root,COG1217@2|Bacteria,2GJUJ@201174|Actinobacteria,4CYX3@85004|Bifidobacteriales 201174|Actinobacteria T Elongation factor G C-terminus typA - - ko:K06207 - - - - ko00000 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2 GGPLMPOG_01506 547043.BIFPSEUDO_02980 1.43e-135 383.0 2E9EF@1|root,333MW@2|Bacteria,2IKWQ@201174|Actinobacteria,4D10T@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01507 547043.BIFPSEUDO_02979 9.2e-244 668.0 COG0077@1|root,COG0077@2|Bacteria,2GJQ5@201174|Actinobacteria,4CZ61@85004|Bifidobacteriales 201174|Actinobacteria E Prephenate dehydratase pheA - 4.2.1.51,5.4.99.5 ko:K04518,ko:K14170 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R00691,R01373,R01715 RC00360,RC03116 ko00000,ko00001,ko00002,ko01000 - - - ACT,PDT GGPLMPOG_01508 547043.BIFPSEUDO_02978 2.11e-250 687.0 COG0287@1|root,COG0287@2|Bacteria,2GKB4@201174|Actinobacteria,4CYV2@85004|Bifidobacteriales 201174|Actinobacteria E Prephenate dehydrogenase tyrA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12 ko:K00210,ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00025 R01728 RC00125 ko00000,ko00001,ko00002,ko01000 - - - PDH GGPLMPOG_01509 547043.BIFPSEUDO_02977 2.11e-46 149.0 2BGJ3@1|root,32AHC@2|Bacteria,2IR91@201174|Actinobacteria,4D17H@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01511 547043.BIFPSEUDO_02976 2.28e-219 605.0 COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4CZCX@85004|Bifidobacteriales 201174|Actinobacteria D Belongs to the 'phage' integrase family. XerC subfamily xerC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03733,ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase GGPLMPOG_01512 547043.BIFPSEUDO_02975 0.0 1080.0 COG4166@1|root,COG4166@2|Bacteria,2GIUH@201174|Actinobacteria,4CZFK@85004|Bifidobacteriales 201174|Actinobacteria E ABC transporter, substrate-binding protein, family 5 dppA - - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 GGPLMPOG_01513 547043.BIFPSEUDO_02974 0.0 1100.0 COG4166@1|root,COG4166@2|Bacteria,2GIUH@201174|Actinobacteria,4CZFK@85004|Bifidobacteriales 201174|Actinobacteria E ABC transporter, substrate-binding protein, family 5 dppA - - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 GGPLMPOG_01514 547043.BIFPSEUDO_02973 1.45e-206 573.0 COG0601@1|root,COG0601@2|Bacteria,2GJ2C@201174|Actinobacteria,4CZSV@85004|Bifidobacteriales 201174|Actinobacteria EP Binding-protein-dependent transport system inner membrane component dppB - - ko:K02033,ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1 GGPLMPOG_01515 547043.BIFPSEUDO_02972 1.43e-224 619.0 COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria,4CYQF@85004|Bifidobacteriales 201174|Actinobacteria EP N-terminal TM domain of oligopeptide transport permease C dppC - - ko:K02034,ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1,OppC_N GGPLMPOG_01516 547043.BIFPSEUDO_02971 0.0 1306.0 COG0444@1|root,COG1123@1|root,COG0444@2|Bacteria,COG4172@2|Bacteria,2GIXV@201174|Actinobacteria,4D2V0@85004|Bifidobacteriales 201174|Actinobacteria EP Oligopeptide/dipeptide transporter, C-terminal region - - - ko:K02031,ko:K02032 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY GGPLMPOG_01517 547043.BIFPSEUDO_02970 1.67e-219 603.0 COG0708@1|root,COG0708@2|Bacteria,2GKIS@201174|Actinobacteria,4CYVB@85004|Bifidobacteriales 201174|Actinobacteria L Endonuclease/Exonuclease/phosphatase family xth - 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos GGPLMPOG_01518 547043.BIFPSEUDO_02969 3.66e-194 539.0 28J4D@1|root,2Z90C@2|Bacteria,2GJYC@201174|Actinobacteria,4CZG1@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF3710) - - - - - - - - - - - - DUF3710 GGPLMPOG_01519 547043.BIFPSEUDO_02968 1.09e-171 479.0 2AVV0@1|root,31MNQ@2|Bacteria,2GJKP@201174|Actinobacteria,4CYQX@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF3159) - - - - - - - - - - - - DUF3159 GGPLMPOG_01520 547043.BIFPSEUDO_02967 5.58e-309 841.0 COG2265@1|root,COG2265@2|Bacteria,2GIR3@201174|Actinobacteria,4CYYN@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family rumA - 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - TRAM,tRNA_U5-meth_tr GGPLMPOG_01521 547043.BIFPSEUDO_02966 2.14e-98 288.0 2AVVG@1|root,31MP9@2|Bacteria,2INFG@201174|Actinobacteria,4D12J@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - Peripla_BP_4 GGPLMPOG_01522 547043.BIFPSEUDO_02965 0.0 1580.0 COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4CYS1@85004|Bifidobacteriales 201174|Actinobacteria P E1-E2 ATPase ctpE GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 - ko:K12952 - - - - ko00000,ko01000 3.A.3.23 - - E1-E2_ATPase,Hydrolase GGPLMPOG_01523 547043.BIFPSEUDO_02964 0.0 1791.0 COG1048@1|root,COG1048@2|Bacteria,2GJD5@201174|Actinobacteria,4CZ3T@85004|Bifidobacteriales 201174|Actinobacteria C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate acnA GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008198,GO:0009060,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0030312,GO:0030350,GO:0032787,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C GGPLMPOG_01524 547043.BIFPSEUDO_02963 0.0 868.0 COG0534@1|root,COG0534@2|Bacteria,2HZA6@201174|Actinobacteria,4CZ8I@85004|Bifidobacteriales 201174|Actinobacteria V Psort location CytoplasmicMembrane, score 9.99 - - - - - - - - - - - - MatE GGPLMPOG_01525 547043.BIFPSEUDO_02962 5.47e-151 424.0 COG0110@1|root,COG0110@2|Bacteria,2GNUB@201174|Actinobacteria,4CZ5K@85004|Bifidobacteriales 201174|Actinobacteria S Bacterial transferase hexapeptide repeat protein - - 2.3.1.18,2.3.1.79 ko:K00633,ko:K00661 - - - - ko00000,ko01000 - - - Hexapep,Hexapep_2,Mac GGPLMPOG_01526 547043.BIFPSEUDO_02961 4.7e-267 729.0 COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,2I2G7@201174|Actinobacteria,4D06R@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - AraC_binding,Cupin_2,HTH_18 GGPLMPOG_01527 547043.BIFPSEUDO_02960 3.96e-292 799.0 COG0842@1|root,COG0842@2|Bacteria,2H9HW@201174|Actinobacteria,4CZ1J@85004|Bifidobacteriales 201174|Actinobacteria V ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 GGPLMPOG_01528 547043.BIFPSEUDO_02959 2.98e-287 786.0 COG0842@1|root,COG0842@2|Bacteria,2IBJP@201174|Actinobacteria,4CZD5@85004|Bifidobacteriales 201174|Actinobacteria V ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 GGPLMPOG_01529 547043.BIFPSEUDO_02958 1.72e-242 665.0 COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4CYUQ@85004|Bifidobacteriales 201174|Actinobacteria V ATPases associated with a variety of cellular activities - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 GGPLMPOG_01530 547043.BIFPSEUDO_02957 3.83e-313 854.0 COG4585@1|root,COG4585@2|Bacteria,2I9G4@201174|Actinobacteria,4CZHY@85004|Bifidobacteriales 201174|Actinobacteria T Histidine kinase - - - - - - - - - - - - HisKA_3 GGPLMPOG_01531 547043.BIFPSEUDO_02956 3.27e-150 423.0 COG2197@1|root,COG2197@2|Bacteria,2IBZ9@201174|Actinobacteria,4D07J@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg GGPLMPOG_01532 547043.BIFPSEUDO_02955 0.0 1381.0 COG1479@1|root,COG1479@2|Bacteria,2I99F@201174|Actinobacteria,4CZ4G@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function DUF262 - - - - - - - - - - - - DUF1524,DUF262 GGPLMPOG_01533 547043.BIFPSEUDO_02954 8.7e-166 463.0 COG2197@1|root,COG2197@2|Bacteria,2GN80@201174|Actinobacteria,4CZRF@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg,Sigma70_r4_2 GGPLMPOG_01534 547043.BIFPSEUDO_02953 2.31e-278 766.0 COG4585@1|root,COG4585@2|Bacteria,2GNBG@201174|Actinobacteria,4CZG6@85004|Bifidobacteriales 201174|Actinobacteria T Histidine kinase - - - - - - - - - - - - HisKA_3 GGPLMPOG_01535 547043.BIFPSEUDO_02952 2.71e-145 415.0 2EGCD@1|root,33A46@2|Bacteria,2HZ8E@201174|Actinobacteria,4CYRF@85004|Bifidobacteriales 201174|Actinobacteria S Domain of unknown function (DUF5067) - - - - - - - - - - - - DUF4190,DUF5067 GGPLMPOG_01536 547043.BIFPSEUDO_02951 4.11e-170 478.0 COG0670@1|root,COG0670@2|Bacteria,2I98Y@201174|Actinobacteria,4CZIJ@85004|Bifidobacteriales 201174|Actinobacteria S Belongs to the BI1 family - - - ko:K06890 - - - - ko00000 - - - Bax1-I GGPLMPOG_01537 547043.BIFPSEUDO_02950 2.28e-226 625.0 COG0697@1|root,COG0697@2|Bacteria,2I8X5@201174|Actinobacteria,4D0BH@85004|Bifidobacteriales 201174|Actinobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA GGPLMPOG_01538 547043.BIFPSEUDO_02949 5.72e-200 553.0 COG2357@1|root,COG2357@2|Bacteria,2GKF8@201174|Actinobacteria,4CYXP@85004|Bifidobacteriales 201174|Actinobacteria S Region found in RelA / SpoT proteins ywaC - 2.7.6.5 ko:K07816 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - - RelA_SpoT GGPLMPOG_01539 547043.BIFPSEUDO_02948 0.0 963.0 COG0621@1|root,COG0621@2|Bacteria,2GJEV@201174|Actinobacteria,4CZFB@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB - 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 GGPLMPOG_01540 547043.BIFPSEUDO_02947 3.76e-245 674.0 COG0324@1|root,COG0324@2|Bacteria,2GKFT@201174|Actinobacteria,4CZNS@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT GGPLMPOG_01542 547043.BIFPSEUDO_02946 0.0 1795.0 COG1674@1|root,COG1674@2|Bacteria,2GK3T@201174|Actinobacteria,4CZ5T@85004|Bifidobacteriales 201174|Actinobacteria D FtsK SpoIIIE family protein ftsK GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma GGPLMPOG_01543 547043.BIFPSEUDO_02945 1.29e-159 447.0 COG0558@1|root,COG0558@2|Bacteria,2GK5D@201174|Actinobacteria,4CZ36@85004|Bifidobacteriales 201174|Actinobacteria I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pgsA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 - R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf GGPLMPOG_01544 547043.BIFPSEUDO_02944 7.04e-127 361.0 COG1546@1|root,COG1546@2|Bacteria,2IQ8T@201174|Actinobacteria,4D0CM@85004|Bifidobacteriales 201174|Actinobacteria S Belongs to the CinA family cinA - 3.5.1.42 ko:K03743 ko00760,map00760 - R02322 RC00100 ko00000,ko00001,ko01000 - - - CinA GGPLMPOG_01545 547043.BIFPSEUDO_02943 3.83e-104 302.0 COG1426@1|root,COG1426@2|Bacteria,2I2G5@201174|Actinobacteria,4D0PT@85004|Bifidobacteriales 201174|Actinobacteria K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_31 GGPLMPOG_01546 547043.BIFPSEUDO_02942 7.07e-61 187.0 2EFU9@1|root,339KE@2|Bacteria,2GQJW@201174|Actinobacteria,4D16T@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF3046) - - - - - - - - - - - - DUF3046 GGPLMPOG_01547 547043.BIFPSEUDO_02941 4.97e-271 743.0 COG0468@1|root,COG0468@2|Bacteria,2GJ4P@201174|Actinobacteria,4CYYY@85004|Bifidobacteriales 201174|Actinobacteria L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA GGPLMPOG_01548 547043.BIFPSEUDO_02940 1.56e-160 449.0 COG2137@1|root,COG2137@2|Bacteria,2INKM@201174|Actinobacteria,4D0Y4@85004|Bifidobacteriales 201174|Actinobacteria S Modulates RecA activity recX - - ko:K03565 - - - - ko00000,ko03400 - - - RecX GGPLMPOG_01549 547043.BIFPSEUDO_02938 5.45e-153 430.0 COG1544@1|root,COG1544@2|Bacteria,2GMYF@201174|Actinobacteria,4CZ3H@85004|Bifidobacteriales 201174|Actinobacteria J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase hpf GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - ko:K05808 - - - - ko00000,ko03009 - - - Ribosom_S30AE_C,Ribosomal_S30AE GGPLMPOG_01550 547043.BIFPSEUDO_02937 0.0 1876.0 COG0653@1|root,COG0653@2|Bacteria,2GIRT@201174|Actinobacteria,4CYX6@85004|Bifidobacteriales 201174|Actinobacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW GGPLMPOG_01551 547043.BIFPSEUDO_02936 9.25e-247 678.0 COG0547@1|root,COG0547@2|Bacteria,2GM4G@201174|Actinobacteria,4CZKZ@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 ko:K00766 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R01073 RC00440 ko00000,ko00001,ko00002,ko01000 - - - Glycos_trans_3N,Glycos_transf_3 GGPLMPOG_01552 547043.BIFPSEUDO_02934 2.6e-128 366.0 2AP35@1|root,31E4N@2|Bacteria,2IBUY@201174|Actinobacteria,4D0R7@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01553 547043.BIFPSEUDO_02933 8.73e-171 476.0 COG0204@1|root,COG0204@2|Bacteria,2GJ6V@201174|Actinobacteria,4CZBB@85004|Bifidobacteriales 201174|Actinobacteria I Phosphate acyltransferases plsC2 - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase GGPLMPOG_01555 566552.BIFCAT_01614 2.09e-118 340.0 COG1704@1|root,COG1704@2|Bacteria,2GPS4@201174|Actinobacteria,4CZE2@85004|Bifidobacteriales 201174|Actinobacteria S LemA family lemA - - ko:K03744 - - - - ko00000 - - - LemA GGPLMPOG_01556 547043.BIFPSEUDO_02702 0.0 1166.0 COG4907@1|root,COG4907@2|Bacteria,2HZD2@201174|Actinobacteria,4CZV5@85004|Bifidobacteriales 201174|Actinobacteria S Predicted membrane protein (DUF2207) - - - - - - - - - - - - DUF2207 GGPLMPOG_01557 547043.BIFPSEUDO_02701 1.53e-217 599.0 COG0667@1|root,COG0667@2|Bacteria,2GJ6R@201174|Actinobacteria,4CZB6@85004|Bifidobacteriales 201174|Actinobacteria C Oxidoreductase, aldo keto reductase family protein - - - - - - - - - - - - Aldo_ket_red GGPLMPOG_01558 566552.BIFCAT_01611 0.0 1021.0 COG0826@1|root,COG0826@2|Bacteria,2GKTB@201174|Actinobacteria,4CZA1@85004|Bifidobacteriales 201174|Actinobacteria O Peptidase family U32 C-terminal domain - - - ko:K08303 ko05120,map05120 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_U32,Peptidase_U32_C GGPLMPOG_01559 566552.BIFCAT_01610 2.31e-234 645.0 COG1496@1|root,COG1496@2|Bacteria,2GN1M@201174|Actinobacteria,4CZBI@85004|Bifidobacteriales 201174|Actinobacteria Q Multi-copper polyphenol oxidoreductase laccase yfiH GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944 - ko:K05810 - - - - ko00000,ko01000 - - - Cu-oxidase_4 GGPLMPOG_01560 547043.BIFPSEUDO_02697 9.79e-193 535.0 COG1211@1|root,COG1211@2|Bacteria,2GNHP@201174|Actinobacteria,4CYVZ@85004|Bifidobacteriales 201174|Actinobacteria I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) ispD - 1.1.1.405,2.7.7.40,2.7.7.60 ko:K00991,ko:K21681 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 M00096 R01525,R02921,R05633 RC00002,RC00089 ko00000,ko00001,ko00002,ko01000 - - - IspD,adh_short GGPLMPOG_01561 566552.BIFCAT_01608 1.97e-160 449.0 COG2039@1|root,COG2039@2|Bacteria,2GN39@201174|Actinobacteria,4CZ57@85004|Bifidobacteriales 201174|Actinobacteria O Removes 5-oxoproline from various penultimate amino acid residues except L-proline pcp - 3.4.19.3 ko:K01304 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C15 GGPLMPOG_01562 547043.BIFPSEUDO_02695 7.66e-147 437.0 COG1196@1|root,COG1196@2|Bacteria,2HZ99@201174|Actinobacteria,4CZ0S@85004|Bifidobacteriales 201174|Actinobacteria D nuclear chromosome segregation - - - - - - - - - - - - DivIVA GGPLMPOG_01563 566552.BIFCAT_01606 0.0 919.0 COG3579@1|root,COG3579@2|Bacteria,2GNYU@201174|Actinobacteria,4CZDZ@85004|Bifidobacteriales 201174|Actinobacteria E Peptidase C1-like family pepC2 - 3.4.22.40 ko:K01372 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C1_2 GGPLMPOG_01564 547043.BIFPSEUDO_02693 6.27e-270 739.0 COG0722@1|root,COG0722@2|Bacteria,2GMVF@201174|Actinobacteria,4CZMR@85004|Bifidobacteriales 201174|Actinobacteria E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) aroG - 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - - DAHP_synth_1 GGPLMPOG_01565 547043.BIFPSEUDO_02692 1.44e-281 770.0 COG0722@1|root,COG0722@2|Bacteria,2GMVF@201174|Actinobacteria,4CZ7I@85004|Bifidobacteriales 201174|Actinobacteria E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) aroG - 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - - DAHP_synth_1 GGPLMPOG_01566 566552.BIFCAT_01603 1.22e-157 443.0 COG0775@1|root,COG0775@2|Bacteria,2I8GZ@201174|Actinobacteria,4CYTM@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively mtnN - 3.2.2.9 ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 M00034,M00609 R00194,R01401 RC00063,RC00318 ko00000,ko00001,ko00002,ko01000 - - - PNP_UDP_1 GGPLMPOG_01567 566552.BIFCAT_01602 4.82e-279 768.0 COG5002@1|root,COG5002@2|Bacteria,2GJY7@201174|Actinobacteria,4CZ42@85004|Bifidobacteriales 201174|Actinobacteria T His Kinase A (phosphoacceptor) domain phoR - 2.7.13.3 ko:K07636,ko:K07768 ko02020,map02020 M00434,M00443 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS_4 GGPLMPOG_01568 547043.BIFPSEUDO_02689 2.31e-166 465.0 COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria,4CZTX@85004|Bifidobacteriales 201174|Actinobacteria KT Transcriptional regulatory protein, C terminal regX3 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141 - ko:K07776 ko02020,map02020 M00443 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C GGPLMPOG_01569 566552.BIFCAT_01600 5.23e-257 706.0 COG0226@1|root,COG0226@2|Bacteria,2GJXD@201174|Actinobacteria,4CYTZ@85004|Bifidobacteriales 201174|Actinobacteria P Part of the ABC transporter complex PstSACB involved in phosphate import pstS - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 GGPLMPOG_01570 547043.BIFPSEUDO_02686 1.5e-208 578.0 COG0573@1|root,COG0573@2|Bacteria,2GJDA@201174|Actinobacteria,4CYV0@85004|Bifidobacteriales 201174|Actinobacteria P probably responsible for the translocation of the substrate across the membrane pstC - - ko:K02037 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 GGPLMPOG_01571 547043.BIFPSEUDO_02685 1.92e-218 605.0 COG0581@1|root,COG0581@2|Bacteria,2I2F2@201174|Actinobacteria,4D2UW@85004|Bifidobacteriales 201174|Actinobacteria P Phosphate transport system permease pstA - - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 GGPLMPOG_01572 1435051.BMOU_1668 6.41e-190 526.0 COG1117@1|root,COG1117@2|Bacteria,2GJQ3@201174|Actinobacteria,4CYVE@85004|Bifidobacteriales 201174|Actinobacteria P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran GGPLMPOG_01573 547043.BIFPSEUDO_02682 9.44e-186 519.0 COG0803@1|root,COG0803@2|Bacteria,2GM1K@201174|Actinobacteria,4CZ99@85004|Bifidobacteriales 201174|Actinobacteria P Zinc-uptake complex component A periplasmic - - - ko:K02077 - M00244 - - ko00000,ko00002,ko02000 3.A.1.15 - - ZnuA GGPLMPOG_01574 547043.BIFPSEUDO_02681 9.45e-315 859.0 COG2252@1|root,COG2252@2|Bacteria,2GKYD@201174|Actinobacteria,4CZHD@85004|Bifidobacteriales 201174|Actinobacteria S Permease family - - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - - Xan_ur_permease GGPLMPOG_01575 401473.BDP_0394 5.91e-114 327.0 COG0244@1|root,COG0244@2|Bacteria,2GM0V@201174|Actinobacteria,4CZFP@85004|Bifidobacteriales 201174|Actinobacteria J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02864 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L10 GGPLMPOG_01576 401473.BDP_0395 5.66e-69 210.0 COG0222@1|root,COG0222@2|Bacteria,2IKNW@201174|Actinobacteria,4D0W2@85004|Bifidobacteriales 201174|Actinobacteria J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation rplL GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - ko:K02935 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L12,Ribosomal_L12_N GGPLMPOG_01577 547043.BIFPSEUDO_02677 1.08e-231 650.0 COG1716@1|root,COG1716@2|Bacteria,2GIT6@201174|Actinobacteria,4CYX9@85004|Bifidobacteriales 201174|Actinobacteria T Forkhead associated domain - - - - - - - - - - - - FHA GGPLMPOG_01578 547043.BIFPSEUDO_02676 0.0 2265.0 COG1112@1|root,COG1112@2|Bacteria,2GKJW@201174|Actinobacteria,4CYY9@85004|Bifidobacteriales 201174|Actinobacteria L Superfamily I DNA and RNA helicases and helicase subunits - - - - - - - - - - - - AAA_11,AAA_12,DUF4011 GGPLMPOG_01579 566552.BIFCAT_01589 2.9e-49 157.0 2B18D@1|root,31TNU@2|Bacteria,2GSR6@201174|Actinobacteria,4D1ET@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01580 566552.BIFCAT_01588 3.04e-116 338.0 COG1261@1|root,COG1261@2|Bacteria,2IIYF@201174|Actinobacteria,4D0YD@85004|Bifidobacteriales 201174|Actinobacteria NO SAF - - - - - - - - - - - - ChapFlgA,SAF GGPLMPOG_01581 547043.BIFPSEUDO_02673 2.78e-41 135.0 COG2331@1|root,COG2331@2|Bacteria,2IQHE@201174|Actinobacteria,4D1ES@85004|Bifidobacteriales 201174|Actinobacteria S Putative regulatory protein - - - - - - - - - - - - Zn-ribbon_8 GGPLMPOG_01582 547043.BIFPSEUDO_02672 1.01e-128 369.0 COG0212@1|root,COG0212@2|Bacteria,2IKWR@201174|Actinobacteria,4D12B@85004|Bifidobacteriales 201174|Actinobacteria H 5-formyltetrahydrofolate cyclo-ligase family ygfA - 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 - R02301 RC00183 ko00000,ko00001,ko01000 - - - 5-FTHF_cyc-lig GGPLMPOG_01583 566552.BIFCAT_01585 1.33e-156 439.0 COG1670@1|root,COG1670@2|Bacteria,2HAFI@201174|Actinobacteria,4CZRR@85004|Bifidobacteriales 201174|Actinobacteria J Acetyltransferase (GNAT) domain rimJ - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 GGPLMPOG_01584 566552.BIFCAT_01584 4.21e-215 602.0 2E03N@1|root,32VSG@2|Bacteria,2GQE4@201174|Actinobacteria,4CYUX@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01585 1680.BADO_0302 3.49e-63 193.0 COG0234@1|root,COG0234@2|Bacteria,2IKTH@201174|Actinobacteria,4D101@85004|Bifidobacteriales 201174|Actinobacteria O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 GGPLMPOG_01589 1437600.JDUI01000014_gene1019 7.79e-35 118.0 COG0267@1|root,COG0267@2|Bacteria,2GQFG@201174|Actinobacteria,4D1EA@85004|Bifidobacteriales 201174|Actinobacteria J Ribosomal protein L33 rpmG - - ko:K02913 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L33 GGPLMPOG_01590 566552.BIFCAT_01577 4.73e-267 733.0 COG0812@1|root,COG0812@2|Bacteria,2GIV2@201174|Actinobacteria,4CZSJ@85004|Bifidobacteriales 201174|Actinobacteria M Cell wall formation murB - 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - - FAD_binding_4,MurB_C GGPLMPOG_01591 547043.BIFPSEUDO_02661 0.0 934.0 COG0531@1|root,COG0531@2|Bacteria,2GJ75@201174|Actinobacteria,4CYZA@85004|Bifidobacteriales 201174|Actinobacteria E aromatic amino acid transport protein AroP K03293 - - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 GGPLMPOG_01592 547043.BIFPSEUDO_02660 2.61e-78 232.0 COG1146@1|root,COG1146@2|Bacteria,2IKVN@201174|Actinobacteria,4D11B@85004|Bifidobacteriales 201174|Actinobacteria C 4Fe-4S binding domain fdxA GO:0001666,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0009628,GO:0036293,GO:0043207,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0070482,GO:0075136 - ko:K05524 - - - - ko00000 - - - Fer4 GGPLMPOG_01593 547043.BIFPSEUDO_02659 1.13e-271 744.0 COG0436@1|root,COG0436@2|Bacteria,2GJMI@201174|Actinobacteria,4CZ91@85004|Bifidobacteriales 201174|Actinobacteria E Aminotransferase class I and II dapC - - - - - - - - - - - Aminotran_1_2 GGPLMPOG_01594 1147128.BAST_0233 4.05e-42 158.0 COG3250@1|root,COG3250@2|Bacteria,2ICNG@201174|Actinobacteria,4CZQA@85004|Bifidobacteriales 201174|Actinobacteria G Glycosyl hydrolase family 2, sugar binding domain protein - - 3.1.1.53 ko:K05970 - - - - ko00000,ko01000 - - - SASA GGPLMPOG_01595 1680.BADO_0308 0.0 1423.0 COG1653@1|root,COG1653@2|Bacteria,2HT29@201174|Actinobacteria,4CZ28@85004|Bifidobacteriales 201174|Actinobacteria G Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - Beta_helix,DUF1565 GGPLMPOG_01596 547043.BIFPSEUDO_02650 1.13e-298 811.0 COG3405@1|root,COG3405@2|Bacteria,2IA68@201174|Actinobacteria,4CZYP@85004|Bifidobacteriales 201174|Actinobacteria G CBM9 module, glycoside hydrolase family 8 protein and carbohydrate esterase family 4 protein K01238 - - 3.2.1.156 ko:K15531 - - - - ko00000,ko01000 - GH8 - Glyco_hydro_8 GGPLMPOG_01597 566552.BIFCAT_01563 0.0 1114.0 COG3507@1|root,COG3507@2|Bacteria,2GIW3@201174|Actinobacteria,4D08K@85004|Bifidobacteriales 201174|Actinobacteria G candidate polyfunctional acetylxylan esterase b-xylosidase A-L-arabinofuranosidase, CBM9 module, glycoside hydrolase family 43 protein and carbohydrate esterase family 6 protein K01238 - - - - - - - - - - - - Glyco_hydro_43 GGPLMPOG_01598 566552.BIFCAT_01562 0.0 1008.0 COG2272@1|root,COG2272@2|Bacteria,2GJCN@201174|Actinobacteria,4D02Y@85004|Bifidobacteriales 201174|Actinobacteria I Belongs to the type-B carboxylesterase lipase family - - - ko:K03929 - - - - ko00000,ko01000 - CE10 - COesterase GGPLMPOG_01601 547043.BIFPSEUDO_02645 1.11e-285 783.0 COG0389@1|root,COG0389@2|Bacteria,2GKBI@201174|Actinobacteria,4CZHT@85004|Bifidobacteriales 201174|Actinobacteria L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB - 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - HHH_5,IMS,IMS_C,IMS_HHH GGPLMPOG_01602 547043.BIFPSEUDO_02644 0.0 874.0 COG2843@1|root,COG2843@2|Bacteria,2GK15@201174|Actinobacteria,4D081@85004|Bifidobacteriales 201174|Actinobacteria M Bacterial capsule synthesis protein PGA_cap - - - ko:K07282 - - - - ko00000 - - - PGA_cap GGPLMPOG_01603 547043.BIFPSEUDO_02643 1.35e-237 653.0 COG0111@1|root,COG0111@2|Bacteria,2GKTT@201174|Actinobacteria,4CZRS@85004|Bifidobacteriales 201174|Actinobacteria EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family pdxB - - - - - - - - - - - 2-Hacid_dh,2-Hacid_dh_C GGPLMPOG_01604 547043.BIFPSEUDO_02642 1.63e-146 413.0 COG1739@1|root,COG1739@2|Bacteria,2GMM4@201174|Actinobacteria,4CZH8@85004|Bifidobacteriales 201174|Actinobacteria S Uncharacterized protein family UPF0029 yigZ - - - - - - - - - - - DUF1949,UPF0029 GGPLMPOG_01605 547043.BIFPSEUDO_02641 3.5e-157 442.0 2BMRI@1|root,32GAY@2|Bacteria,2GMIA@201174|Actinobacteria,4CZFZ@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - LRV GGPLMPOG_01606 547043.BIFPSEUDO_02640 0.0 1464.0 COG1640@1|root,COG1640@2|Bacteria,2GM5Z@201174|Actinobacteria,4CZC7@85004|Bifidobacteriales 201174|Actinobacteria G 4-alpha-glucanotransferase malQ GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.4.1.25 ko:K00705 ko00500,ko01100,map00500,map01100 - R05196 RC00049 ko00000,ko00001,ko01000 - GH77 - Glyco_hydro_77 GGPLMPOG_01607 547043.BIFPSEUDO_02639 2.26e-104 301.0 COG0102@1|root,COG0102@2|Bacteria,2IFG1@201174|Actinobacteria,4D0PV@85004|Bifidobacteriales 201174|Actinobacteria J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02871 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L13 GGPLMPOG_01608 547043.BIFPSEUDO_02638 1.21e-99 290.0 COG0103@1|root,COG0103@2|Bacteria,2GNDY@201174|Actinobacteria,4CZ9Y@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the universal ribosomal protein uS9 family rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02996 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S9 GGPLMPOG_01609 547043.BIFPSEUDO_02637 0.0 1684.0 COG1523@1|root,COG1523@2|Bacteria,2GJ00@201174|Actinobacteria,4CYZ1@85004|Bifidobacteriales 201174|Actinobacteria G Belongs to the glycosyl hydrolase 13 family glgX - 3.2.1.196,3.2.1.68 ko:K01214,ko:K02438 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02111,R09995,R11261 - ko00000,ko00001,ko00002,ko01000 - CBM48,GH13 - Alpha-amylase,CBM_48 GGPLMPOG_01610 78345.BMERY_0604 1.17e-225 623.0 COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria,4D04X@85004|Bifidobacteriales 201174|Actinobacteria C Zinc-binding dehydrogenase - - 1.1.1.1,1.1.1.287,1.6.5.5 ko:K00001,ko:K00344,ko:K17818 ko00010,ko00040,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R07143,R07144,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00102,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N GGPLMPOG_01611 78346.BRUM_0709 3.12e-287 788.0 COG0477@1|root,COG2814@2|Bacteria,2GPRH@201174|Actinobacteria,4D048@85004|Bifidobacteriales 201174|Actinobacteria EGP Major Facilitator Superfamily csbX - - - - - - - - - - - MFS_1 GGPLMPOG_01612 1680.BADO_0321 6.01e-99 286.0 COG0346@1|root,COG0346@2|Bacteria,2IHBC@201174|Actinobacteria,4D0P3@85004|Bifidobacteriales 201174|Actinobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase GGPLMPOG_01613 547043.BIFPSEUDO_02634 1.93e-273 748.0 COG1940@1|root,COG1940@2|Bacteria,2I7R8@201174|Actinobacteria,4CZZ7@85004|Bifidobacteriales 201174|Actinobacteria GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565 - - - - - - - - - - - - HTH_24,MarR,ROK GGPLMPOG_01614 547043.BIFPSEUDO_02633 9.26e-300 819.0 COG0477@1|root,COG2814@2|Bacteria,2GPRH@201174|Actinobacteria,4D048@85004|Bifidobacteriales 201174|Actinobacteria EGP Major Facilitator Superfamily csbX - - - - - - - - - - - MFS_1 GGPLMPOG_01615 547043.BIFPSEUDO_02632 5.19e-251 688.0 COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria,4D04X@85004|Bifidobacteriales 201174|Actinobacteria C Zinc-binding dehydrogenase - - 1.1.1.9 ko:K05351 ko00040,ko01100,map00040,map01100 M00014 R01896 RC00102 ko00000,ko00001,ko00002,ko01000 - - - ADH_N,ADH_zinc_N GGPLMPOG_01616 547043.BIFPSEUDO_02631 8.4e-234 643.0 COG2207@1|root,COG2207@2|Bacteria,2HZE7@201174|Actinobacteria,4D00U@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - AraC_binding,HTH_18 GGPLMPOG_01617 547043.BIFPSEUDO_02630 0.0 1792.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,2GJI2@201174|Actinobacteria,4CZ8F@85004|Bifidobacteriales 201174|Actinobacteria C belongs to the iron- containing alcohol dehydrogenase family adhE - 1.1.1.1,1.2.1.10,1.2.1.81 ko:K04072,ko:K15515 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 - R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 ko00000,ko00001,ko01000 - - - Aldedh,Fe-ADH GGPLMPOG_01618 1435051.BMOU_1705 5.42e-67 203.0 COG0051@1|root,COG0051@2|Bacteria,2IHRA@201174|Actinobacteria,4D0UT@85004|Bifidobacteriales 201174|Actinobacteria J Involved in the binding of tRNA to the ribosomes rpsJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02946 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S10 GGPLMPOG_01619 547043.BIFPSEUDO_02627 1.64e-151 426.0 COG0087@1|root,COG0087@2|Bacteria,2GJXT@201174|Actinobacteria,4CYQD@85004|Bifidobacteriales 201174|Actinobacteria J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit rplC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - ko:K02906 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L3 GGPLMPOG_01620 547043.BIFPSEUDO_02626 3.02e-151 426.0 COG0088@1|root,COG0088@2|Bacteria,2GJYJ@201174|Actinobacteria,4CZSA@85004|Bifidobacteriales 201174|Actinobacteria J Forms part of the polypeptide exit tunnel rplD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02926 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L4 GGPLMPOG_01621 1435051.BMOU_1708 8.86e-62 189.0 COG0089@1|root,COG0089@2|Bacteria,2IQ7V@201174|Actinobacteria,4D11N@85004|Bifidobacteriales 201174|Actinobacteria J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome rplW GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02892 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L23 GGPLMPOG_01622 547043.BIFPSEUDO_02624 2.71e-195 541.0 COG0090@1|root,COG0090@2|Bacteria,2GK7R@201174|Actinobacteria,4CZ5U@85004|Bifidobacteriales 201174|Actinobacteria J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity rplB GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02886 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L2,Ribosomal_L2_C GGPLMPOG_01623 1435051.BMOU_1710 3.44e-63 192.0 COG0185@1|root,COG0185@2|Bacteria,2IKMS@201174|Actinobacteria,4D105@85004|Bifidobacteriales 201174|Actinobacteria J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA rpsS GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016020,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0071944,GO:1990904 - ko:K02965 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S19 GGPLMPOG_01624 1680.BADO_0333 5.42e-75 224.0 COG0091@1|root,COG0091@2|Bacteria,2IM3J@201174|Actinobacteria,4D0UZ@85004|Bifidobacteriales 201174|Actinobacteria J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome rplV GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - ko:K02890 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L22 GGPLMPOG_01625 401473.BDP_0437 2.74e-147 419.0 COG0092@1|root,COG0092@2|Bacteria,2GKF1@201174|Actinobacteria,4CYQN@85004|Bifidobacteriales 201174|Actinobacteria J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation rpsC GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02982 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KH_2,Ribosomal_S3_C GGPLMPOG_01626 1680.BADO_0335 3.85e-98 285.0 COG0197@1|root,COG0197@2|Bacteria,2IFEI@201174|Actinobacteria,4D0Q8@85004|Bifidobacteriales 201174|Actinobacteria J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs rplP GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:0097159,GO:1901363,GO:1990904 - ko:K02878 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L16 GGPLMPOG_01627 547043.BIFPSEUDO_02619 1.37e-50 160.0 COG0255@1|root,COG0255@2|Bacteria,2IQ6V@201174|Actinobacteria,4D181@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the universal ribosomal protein uL29 family rpmC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02904 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L29 GGPLMPOG_01628 78346.BRUM_0723 5.52e-55 171.0 COG0186@1|root,COG0186@2|Bacteria,2IQ68@201174|Actinobacteria,4D10N@85004|Bifidobacteriales 201174|Actinobacteria J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA rpsQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02961 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S17 GGPLMPOG_01629 1437600.JDUI01000009_gene353 2.55e-79 236.0 COG0093@1|root,COG0093@2|Bacteria,2IHNX@201174|Actinobacteria,4D0VI@85004|Bifidobacteriales 201174|Actinobacteria J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome rplN GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071944,GO:0097159,GO:1901363,GO:1990904 - ko:K02874 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L14 GGPLMPOG_01630 1680.BADO_0339 1.05e-66 203.0 COG0198@1|root,COG0198@2|Bacteria,2IKP2@201174|Actinobacteria,4D10I@85004|Bifidobacteriales 201174|Actinobacteria J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit rplX GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02895 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KOW,ribosomal_L24 GGPLMPOG_01631 547043.BIFPSEUDO_02615 1.6e-133 378.0 COG0094@1|root,COG0094@2|Bacteria,2GJW7@201174|Actinobacteria,4CZCA@85004|Bifidobacteriales 201174|Actinobacteria J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits rplE GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02931 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L5,Ribosomal_L5_C GGPLMPOG_01632 1435051.BMOU_1719 4.1e-39 129.0 COG0199@1|root,COG0199@2|Bacteria,2IQ8R@201174|Actinobacteria,4D177@85004|Bifidobacteriales 201174|Actinobacteria J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site rpsN GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02954 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S14 GGPLMPOG_01633 1435051.BMOU_1720 3.93e-90 264.0 COG0096@1|root,COG0096@2|Bacteria,2IHQZ@201174|Actinobacteria,4D0P6@85004|Bifidobacteriales 201174|Actinobacteria J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit rpsH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02994 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S8 GGPLMPOG_01634 547043.BIFPSEUDO_02612 5.66e-124 353.0 COG0097@1|root,COG0097@2|Bacteria,2GK35@201174|Actinobacteria,4CYQV@85004|Bifidobacteriales 201174|Actinobacteria J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center rplF GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02933 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L6 GGPLMPOG_01635 547043.BIFPSEUDO_02611 1.86e-77 231.0 COG0256@1|root,COG0256@2|Bacteria,2IKTX@201174|Actinobacteria,4D0WE@85004|Bifidobacteriales 201174|Actinobacteria J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance rplR GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0008150,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02881 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L18p GGPLMPOG_01636 547043.BIFPSEUDO_02610 5.14e-130 374.0 COG0098@1|root,COG0098@2|Bacteria,2GJW8@201174|Actinobacteria,4CZCD@85004|Bifidobacteriales 201174|Actinobacteria J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body rpsE GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02988 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S5,Ribosomal_S5_C GGPLMPOG_01637 547043.BIFPSEUDO_02609 1.24e-35 120.0 COG1841@1|root,COG1841@2|Bacteria,2GQV0@201174|Actinobacteria,4D1EZ@85004|Bifidobacteriales 201174|Actinobacteria J Ribosomal protein L30p/L7e rpmD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02907 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L30 GGPLMPOG_01638 547043.BIFPSEUDO_02608 5.12e-96 280.0 COG0200@1|root,COG0200@2|Bacteria,2II6M@201174|Actinobacteria,4D0R9@85004|Bifidobacteriales 201174|Actinobacteria J binds to the 23S rRNA rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - ko:K02876 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27A GGPLMPOG_01639 547043.BIFPSEUDO_02607 7.19e-315 858.0 COG0201@1|root,COG0201@2|Bacteria,2GJ26@201174|Actinobacteria,4CYWU@85004|Bifidobacteriales 201174|Actinobacteria U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY GGPLMPOG_01640 547043.BIFPSEUDO_02606 1.05e-127 363.0 COG0563@1|root,COG0563@2|Bacteria,2GJ7T@201174|Actinobacteria,4CZ7Z@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk - 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ADK,ADK_lid GGPLMPOG_01641 1435051.BMOU_1728 6.91e-45 145.0 COG0361@1|root,COG0361@2|Bacteria,2IQ4B@201174|Actinobacteria,4D16H@85004|Bifidobacteriales 201174|Actinobacteria J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex infA - - ko:K02518 - - - - ko00000,ko03012 - - - eIF-1a GGPLMPOG_01642 158787.BSCA_1163 1.47e-20 81.3 COG0257@1|root,COG0257@2|Bacteria,2GWMH@201174|Actinobacteria,4D1NT@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the bacterial ribosomal protein bL36 family rpmJ - - ko:K02919 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L36 GGPLMPOG_01643 1435051.BMOU_1730 6.96e-83 245.0 COG0099@1|root,COG0099@2|Bacteria,2IHPN@201174|Actinobacteria,4D0PQ@85004|Bifidobacteriales 201174|Actinobacteria J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits rpsM GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02952 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S13 GGPLMPOG_01644 1680.BADO_0353 1.48e-85 252.0 COG0100@1|root,COG0100@2|Bacteria,2IFFC@201174|Actinobacteria,4D0PJ@85004|Bifidobacteriales 201174|Actinobacteria J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome rpsK GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02948 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S11 GGPLMPOG_01645 547043.BIFPSEUDO_02601 6.43e-238 654.0 COG0202@1|root,COG0202@2|Bacteria,2GJJ5@201174|Actinobacteria,4CZEN@85004|Bifidobacteriales 201174|Actinobacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L GGPLMPOG_01646 1435051.BMOU_1733 1.21e-87 260.0 COG0203@1|root,COG0203@2|Bacteria,2IHV2@201174|Actinobacteria,4D0PZ@85004|Bifidobacteriales 201174|Actinobacteria J Ribosomal protein L17 rplQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - ko:K02879 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L17 GGPLMPOG_01647 547043.BIFPSEUDO_02599 3.16e-233 642.0 COG0101@1|root,COG0101@2|Bacteria,2GJ6C@201174|Actinobacteria,4CZ8H@85004|Bifidobacteriales 201174|Actinobacteria J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs truA GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0030312,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 GGPLMPOG_01649 547043.BIFPSEUDO_02594 7.32e-110 323.0 2B54U@1|root,31XYD@2|Bacteria,2HXKT@201174|Actinobacteria,4D0IH@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01650 547043.BIFPSEUDO_02593 4.21e-243 669.0 COG0195@1|root,COG0195@2|Bacteria,2GJDJ@201174|Actinobacteria,4CYTW@85004|Bifidobacteriales 201174|Actinobacteria K Participates in both transcription termination and antitermination nusA GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0040007,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - KH_5,NusA_N,S1 GGPLMPOG_01651 1435051.BMOU_1739 0.0 1465.0 COG0532@1|root,COG0532@2|Bacteria,2GKPH@201174|Actinobacteria,4CZ4B@85004|Bifidobacteriales 201174|Actinobacteria J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB - - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,IF-2,IF2_N GGPLMPOG_01652 547043.BIFPSEUDO_02589 1.9e-98 288.0 COG0858@1|root,COG0858@2|Bacteria,2IKXP@201174|Actinobacteria,4CZZZ@85004|Bifidobacteriales 201174|Actinobacteria J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA rbfA - - ko:K02834 - - - - ko00000,ko03009 - - - RBFA GGPLMPOG_01653 566552.BIFCAT_01504 3.51e-241 665.0 COG0130@1|root,COG0130@2|Bacteria,2GJZK@201174|Actinobacteria,4CZED@85004|Bifidobacteriales 201174|Actinobacteria J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs truB GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 ko:K03177 - - - - ko00000,ko01000,ko03016 - - - TruB_C,TruB_C_2,TruB_N GGPLMPOG_01654 547043.BIFPSEUDO_02587 3.39e-276 757.0 COG0196@1|root,COG0196@2|Bacteria,2GKQF@201174|Actinobacteria,4CYXT@85004|Bifidobacteriales 201174|Actinobacteria H riboflavin kinase ribF GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008531,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009124,GO:0009156,GO:0009161,GO:0009165,GO:0009231,GO:0009259,GO:0009260,GO:0009398,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0042364,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046444,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - FAD_syn,Flavokinase GGPLMPOG_01655 566552.BIFCAT_01502 0.0 875.0 COG1066@1|root,COG1066@2|Bacteria,2GMQ0@201174|Actinobacteria,4CZE1@85004|Bifidobacteriales 201174|Actinobacteria O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K04485 - - - - ko00000,ko03400 - - - AAA_25,ATPase,ChlI,Lon_C GGPLMPOG_01656 547043.BIFPSEUDO_02585 9.41e-140 395.0 2EHBK@1|root,33B3F@2|Bacteria,2ICD4@201174|Actinobacteria,4CZY5@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01657 1147128.BAST_1307 5.05e-07 46.6 29UT5@1|root,30G5G@2|Bacteria,2GXCZ@201174|Actinobacteria,4D1N2@85004|Bifidobacteriales 201174|Actinobacteria S Mitochondrial domain of unknown function (DUF1713) - - - - - - - - - - - - DUF1713 GGPLMPOG_01658 547043.BIFPSEUDO_02583 3.43e-163 457.0 COG0120@1|root,COG0120@2|Bacteria,2GMHW@201174|Actinobacteria,4CZDH@85004|Bifidobacteriales 201174|Actinobacteria G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate rpiA - 5.3.1.6 ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056 RC00434 ko00000,ko00001,ko00002,ko01000 - - - Rib_5-P_isom_A GGPLMPOG_01659 547043.BIFPSEUDO_02582 7e-275 753.0 COG0328@1|root,COG0328@2|Bacteria,2GK53@201174|Actinobacteria,4CZGC@85004|Bifidobacteriales 201174|Actinobacteria L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DUF4440,RNase_H GGPLMPOG_01660 547043.BIFPSEUDO_02581 0.0 867.0 COG3290@1|root,COG3290@2|Bacteria,2IBRI@201174|Actinobacteria,4D07Q@85004|Bifidobacteriales 201174|Actinobacteria T GHKL domain - - - - - - - - - - - - HATPase_c_5 GGPLMPOG_01661 547043.BIFPSEUDO_02580 5.08e-196 543.0 COG3279@1|root,COG3279@2|Bacteria,2HY65@201174|Actinobacteria,4D0IP@85004|Bifidobacteriales 201174|Actinobacteria T LytTr DNA-binding domain - - - - - - - - - - - - LytTR,Response_reg GGPLMPOG_01662 547043.BIFPSEUDO_02579 0.0 1132.0 COG0033@1|root,COG0033@2|Bacteria,2H1PI@201174|Actinobacteria,4CZ7X@85004|Bifidobacteriales 201174|Actinobacteria G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II pgm - 5.4.2.2 ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00549 R00959,R01057,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV GGPLMPOG_01663 547043.BIFPSEUDO_02578 0.0 1281.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,2GK6B@201174|Actinobacteria,4CZR7@85004|Bifidobacteriales 201174|Actinobacteria G pts system, glucose-specific IIABC component ptsG - - ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 M00271 - - ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC GGPLMPOG_01664 547043.BIFPSEUDO_02577 7.78e-201 556.0 COG3711@1|root,COG3711@2|Bacteria,2I8K8@201174|Actinobacteria,4D08T@85004|Bifidobacteriales 201174|Actinobacteria K CAT RNA binding domain arbG - - ko:K03488 - - - - ko00000,ko03000 - - - CAT_RBD,PRD,PTS-HPr GGPLMPOG_01665 547043.BIFPSEUDO_02576 2.32e-261 716.0 COG1597@1|root,COG1597@2|Bacteria,2GJ3K@201174|Actinobacteria,4CYTC@85004|Bifidobacteriales 201174|Actinobacteria I Diacylglycerol kinase catalytic domain - - - - - - - - - - - - DAGK_cat GGPLMPOG_01666 547043.BIFPSEUDO_02575 1.25e-311 850.0 COG0172@1|root,COG0172@2|Bacteria,2GIWP@201174|Actinobacteria,4CZ40@85004|Bifidobacteriales 201174|Actinobacteria J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b GGPLMPOG_01668 547043.BIFPSEUDO_02573 1.68e-239 659.0 COG1397@1|root,COG1397@2|Bacteria,2HZ96@201174|Actinobacteria,4CZ01@85004|Bifidobacteriales 201174|Actinobacteria O ADP-ribosylglycohydrolase - - - - - - - - - - - - ADP_ribosyl_GH GGPLMPOG_01669 547043.BIFPSEUDO_02572 1.86e-242 665.0 COG0524@1|root,COG0524@2|Bacteria,2IA3T@201174|Actinobacteria,4CYSM@85004|Bifidobacteriales 201174|Actinobacteria G pfkB family carbohydrate kinase - - - - - - - - - - - - ADP_ribosyl_GH,PfkB GGPLMPOG_01670 547043.BIFPSEUDO_02571 0.0 940.0 COG1457@1|root,COG1457@2|Bacteria,2GJ6B@201174|Actinobacteria,4CZT2@85004|Bifidobacteriales 201174|Actinobacteria U Permease for cytosine/purines, uracil, thiamine, allantoin - - - ko:K03457 - - - - ko00000 2.A.39 - - Transp_cyt_pur GGPLMPOG_01671 566552.BIFCAT_01278 6.83e-133 376.0 COG1335@1|root,COG1335@2|Bacteria,2IN6N@201174|Actinobacteria,4D092@85004|Bifidobacteriales 201174|Actinobacteria Q Isochorismatase family - - - - - - - - - - - - Isochorismatase GGPLMPOG_01672 547043.BIFPSEUDO_02565 2.9e-157 441.0 COG2197@1|root,COG2197@2|Bacteria,2GIVA@201174|Actinobacteria,4CZW8@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn_helix, Lux Regulon tcsR3 - - - - - - - - - - - GerE,Response_reg GGPLMPOG_01673 547043.BIFPSEUDO_02564 0.0 989.0 COG1983@1|root,COG4585@1|root,COG1983@2|Bacteria,COG4585@2|Bacteria,2GJ4J@201174|Actinobacteria,4CZ2U@85004|Bifidobacteriales 201174|Actinobacteria KT PspC domain tcsS3 - - - - - - - - - - - HATPase_c,HATPase_c_2,PspC GGPLMPOG_01674 547043.BIFPSEUDO_02562 9.85e-196 560.0 COG1983@1|root,COG1983@2|Bacteria,2GIVS@201174|Actinobacteria,4CZZT@85004|Bifidobacteriales 201174|Actinobacteria KT PspC domain pspC - - - - - - - - - - - DUF2154,PspC GGPLMPOG_01675 566552.BIFCAT_01283 9.51e-122 348.0 2B2B3@1|root,31UV6@2|Bacteria,2GUI3@201174|Actinobacteria,4D1IV@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01676 566552.BIFCAT_01285 1.06e-148 419.0 2DM2Z@1|root,31HGC@2|Bacteria,2GKMX@201174|Actinobacteria,4CZJ9@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF4125) - - - - - - - - - - - - DUF4125 GGPLMPOG_01677 547043.BIFPSEUDO_02559 0.0 1302.0 COG0457@1|root,COG0457@2|Bacteria,2I7P1@201174|Actinobacteria,4CZTS@85004|Bifidobacteriales 201174|Actinobacteria S Domain of unknown function (DUF4037) - - - - - - - - - - - - DUF4037,TPR_12 GGPLMPOG_01678 566552.BIFCAT_01288 1.88e-271 744.0 COG0477@1|root,COG2814@2|Bacteria,2GK8C@201174|Actinobacteria,4CZ46@85004|Bifidobacteriales 201174|Actinobacteria EGP Major Facilitator Superfamily - - - ko:K08156,ko:K19577 - - - - ko00000,ko02000 2.A.1.2.14,2.A.1.2.65 - - MFS_1 GGPLMPOG_01680 547043.BIFPSEUDO_02556 0.0 1077.0 COG1190@1|root,COG1190@2|Bacteria,2GKE0@201174|Actinobacteria,4CZHM@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the class-II aminoacyl-tRNA synthetase family lysS GO:0008150,GO:0040007 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon GGPLMPOG_01681 547043.BIFPSEUDO_02555 2.9e-245 674.0 COG1609@1|root,COG1609@2|Bacteria,2GJRG@201174|Actinobacteria,4D078@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn _helix lactose operon repressor - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 GGPLMPOG_01682 547043.BIFPSEUDO_02553 0.0 872.0 COG2211@1|root,COG2211@2|Bacteria,2HD4Y@201174|Actinobacteria,4CZRA@85004|Bifidobacteriales 201174|Actinobacteria G Psort location CytoplasmicMembrane, score 10.00 - - - ko:K03292 - - - - ko00000 2.A.2 - - MFS_2 GGPLMPOG_01683 1435051.BMOU_1791 2.99e-125 363.0 COG1073@1|root,COG1073@2|Bacteria,2HW4C@201174|Actinobacteria,4D04D@85004|Bifidobacteriales 201174|Actinobacteria S Serine aminopeptidase, S33 - - - ko:K06889 - - - - ko00000 - - - Abhydrolase_6,Hydrolase_4 GGPLMPOG_01684 547043.BIFPSEUDO_02549 9.77e-267 731.0 COG1575@1|root,COG1575@2|Bacteria,2GJBS@201174|Actinobacteria,4CZHQ@85004|Bifidobacteriales 201174|Actinobacteria H Belongs to the MenA family. Type 1 subfamily menA GO:0003674,GO:0003824,GO:0004659,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA GGPLMPOG_01685 1680.BADO_0384 1.83e-178 496.0 COG0588@1|root,COG0588@2|Bacteria,2GK8F@201174|Actinobacteria,4CZMF@85004|Bifidobacteriales 201174|Actinobacteria G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmA GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0031323,GO:0031329,GO:0032787,GO:0032991,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0060255,GO:0062012,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 GGPLMPOG_01686 547043.BIFPSEUDO_02547 0.0 1288.0 COG4716@1|root,COG4716@2|Bacteria,2GKZ8@201174|Actinobacteria,4CYZK@85004|Bifidobacteriales 201174|Actinobacteria S MCRA family - - 4.2.1.53 ko:K10254 - - - - ko00000,ko01000 - - - MCRA GGPLMPOG_01687 547043.BIFPSEUDO_02546 8.62e-133 379.0 COG0704@1|root,COG0704@2|Bacteria,2GKAD@201174|Actinobacteria,4CZ9B@85004|Bifidobacteriales 201174|Actinobacteria P Plays a role in the regulation of phosphate uptake phoU GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0016020,GO:0019220,GO:0019222,GO:0022611,GO:0031323,GO:0031324,GO:0032502,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042221,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044444,GO:0044464,GO:0045936,GO:0046677,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:0071944,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - ko:K02039 - - - - ko00000 - - - PhoU GGPLMPOG_01688 547043.BIFPSEUDO_02545 1.57e-275 754.0 COG5002@1|root,COG5002@2|Bacteria,2GJY7@201174|Actinobacteria,4CZIM@85004|Bifidobacteriales 201174|Actinobacteria T ATPase histidine kinase DNA gyrase B HSP90 domain protein senX3 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009405,GO:0009987,GO:0016020,GO:0016310,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0051704,GO:0071704,GO:0071944,GO:1901564 2.7.13.3 ko:K07768 ko02020,map02020 M00443 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA GGPLMPOG_01689 547043.BIFPSEUDO_03397 0.0 1007.0 COG0847@1|root,COG0847@2|Bacteria,2IC59@201174|Actinobacteria,4CZY1@85004|Bifidobacteriales 201174|Actinobacteria L Psort location Cytoplasmic, score - - - - - - - - - - - - - GGPLMPOG_01690 547043.BIFPSEUDO_03395 1.64e-158 444.0 COG0242@1|root,COG0242@2|Bacteria,2GNZ9@201174|Actinobacteria,4CZ7M@85004|Bifidobacteriales 201174|Actinobacteria J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase GGPLMPOG_01691 547043.BIFPSEUDO_03394 0.0 883.0 COG1109@1|root,COG1109@2|Bacteria,2GN87@201174|Actinobacteria,4CYZX@85004|Bifidobacteriales 201174|Actinobacteria G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate glmM GO:0008150,GO:0040007 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 - R02060 RC00408 ko00000,ko00001,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV GGPLMPOG_01692 547043.BIFPSEUDO_03392 0.0 2583.0 COG1674@1|root,COG1674@2|Bacteria,2GJBR@201174|Actinobacteria,4D09Y@85004|Bifidobacteriales 201174|Actinobacteria D FtsK/SpoIIIE family eccCa GO:0002790,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009405,GO:0009605,GO:0009607,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0020012,GO:0030312,GO:0030682,GO:0031224,GO:0031226,GO:0032940,GO:0033036,GO:0040007,GO:0042783,GO:0042886,GO:0043207,GO:0044110,GO:0044116,GO:0044117,GO:0044315,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0050896,GO:0051179,GO:0051234,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0075136 - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_SpoIIIE GGPLMPOG_01693 547043.BIFPSEUDO_03391 1.03e-208 581.0 COG1716@1|root,COG1716@2|Bacteria,2IDEM@201174|Actinobacteria,4D0MP@85004|Bifidobacteriales 201174|Actinobacteria T Forkhead associated domain - - - - - - - - - - - - FHA,RDD GGPLMPOG_01694 547043.BIFPSEUDO_03390 1.44e-256 705.0 28ZMR@1|root,2ZMCZ@2|Bacteria,2IF0B@201174|Actinobacteria,4CZME@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01695 547043.BIFPSEUDO_03388 1.96e-88 260.0 2BK54@1|root,32EIR@2|Bacteria,2GQ4V@201174|Actinobacteria,4D1AS@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01696 547043.BIFPSEUDO_03387 8.14e-241 663.0 2AVZD@1|root,31MTS@2|Bacteria,2INKR@201174|Actinobacteria,4D15X@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01697 547043.BIFPSEUDO_03386 1.17e-214 598.0 2AUDB@1|root,31K1A@2|Bacteria,2IK4S@201174|Actinobacteria,4D0XH@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01698 547043.BIFPSEUDO_03385 4.06e-250 699.0 2A3NJ@1|root,30S5Z@2|Bacteria,2HEVI@201174|Actinobacteria,4D0D8@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01699 547043.BIFPSEUDO_03384 0.0 908.0 COG1404@1|root,COG1404@2|Bacteria,2GMBS@201174|Actinobacteria,4CZY0@85004|Bifidobacteriales 201174|Actinobacteria O Subtilase family vpr - - - - - - - - - - - Peptidase_S8 GGPLMPOG_01701 547043.BIFPSEUDO_03382 1.38e-59 184.0 COG4842@1|root,COG4842@2|Bacteria,2GPU5@201174|Actinobacteria,4D17T@85004|Bifidobacteriales 201174|Actinobacteria S Proteins of 100 residues with WXG - - - - - - - - - - - - WXG100 GGPLMPOG_01702 547043.BIFPSEUDO_03381 3.69e-63 194.0 COG4842@1|root,COG4842@2|Bacteria,2IQV4@201174|Actinobacteria,4D1BM@85004|Bifidobacteriales 201174|Actinobacteria S Proteins of 100 residues with WXG - - - - - - - - - - - - WXG100 GGPLMPOG_01703 547043.BIFPSEUDO_03379 1.3e-284 781.0 28MNM@1|root,2ZAY5@2|Bacteria,2HZD8@201174|Actinobacteria,4CZWC@85004|Bifidobacteriales 201174|Actinobacteria S WXG100 protein secretion system (Wss), protein YukD - - - - - - - - - - - - YukD GGPLMPOG_01704 547043.BIFPSEUDO_03378 0.0 1644.0 COG1404@1|root,COG1404@2|Bacteria,2GIRE@201174|Actinobacteria,4D026@85004|Bifidobacteriales 201174|Actinobacteria O Type VII secretion system ESX-1, transport TM domain B mycP - - ko:K14743 - - - - ko00000,ko01000,ko01002,ko03110 - - - Peptidase_S8 GGPLMPOG_01705 547043.BIFPSEUDO_03377 4.24e-218 598.0 2BAF1@1|root,323VH@2|Bacteria,2H8KM@201174|Actinobacteria,4D2H7@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01706 547043.BIFPSEUDO_03376 0.0 1723.0 COG0308@1|root,COG0308@2|Bacteria,2GJJ4@201174|Actinobacteria,4CZH4@85004|Bifidobacteriales 201174|Actinobacteria E Peptidase family M1 domain pepN - 3.4.11.2 ko:K01256,ko:K08776 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - ERAP1_C,Peptidase_M1 GGPLMPOG_01707 547043.BIFPSEUDO_03375 0.0 1254.0 COG0595@1|root,COG0595@2|Bacteria,2GIW7@201174|Actinobacteria,4CZEJ@85004|Bifidobacteriales 201174|Actinobacteria J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay rnj - - ko:K12574 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - Lactamase_B,Lactamase_B_2,RMMBL GGPLMPOG_01708 547043.BIFPSEUDO_03374 1.67e-222 614.0 COG0329@1|root,COG0329@2|Bacteria,2GJ34@201174|Actinobacteria,4CZ34@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS GGPLMPOG_01709 547043.BIFPSEUDO_03373 0.0 1837.0 COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4CZ24@85004|Bifidobacteriales 201174|Actinobacteria P E1-E2 ATPase - - 3.6.3.4,3.6.3.54 ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - Cupredoxin_1,E1-E2_ATPase,HMA,Hydrolase,YHS GGPLMPOG_01710 547043.BIFPSEUDO_03372 7.81e-67 203.0 COG1937@1|root,COG1937@2|Bacteria,2IQAC@201174|Actinobacteria,4D1A2@85004|Bifidobacteriales 201174|Actinobacteria S Metal-sensitive transcriptional repressor csoR GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010035,GO:0010038,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0042221,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0046688,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K21600 - - - - ko00000,ko03000 - - - Trns_repr_metal GGPLMPOG_01711 547043.BIFPSEUDO_03371 4.54e-171 478.0 COG0289@1|root,COG0289@2|Bacteria,2GM2T@201174|Actinobacteria,4CZJ5@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate dapB - 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 - - - DapB_C,DapB_N GGPLMPOG_01712 547043.BIFPSEUDO_03370 4.01e-314 857.0 COG2271@1|root,COG2271@2|Bacteria,2I2GK@201174|Actinobacteria,4CZ0T@85004|Bifidobacteriales 201174|Actinobacteria G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 GGPLMPOG_01713 547043.BIFPSEUDO_03369 0.0 2632.0 COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2GM2E@201174|Actinobacteria,4CZ49@85004|Bifidobacteriales 201174|Actinobacteria L Belongs to the helicase family. UvrD subfamily uvrD2 - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C GGPLMPOG_01714 547043.BIFPSEUDO_03368 0.0 2649.0 COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2GJD0@201174|Actinobacteria,4CYQU@85004|Bifidobacteriales 201174|Actinobacteria L PD-(D/E)XK nuclease superfamily - - - - - - - - - - - - AAA_19,PDDEXK_1,UvrD-helicase,UvrD_C GGPLMPOG_01715 547043.BIFPSEUDO_03366 0.0 930.0 COG0515@1|root,COG0515@2|Bacteria,2GIW5@201174|Actinobacteria,4CZ9N@85004|Bifidobacteriales 201174|Actinobacteria KLT Protein tyrosine kinase pknK - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase GGPLMPOG_01716 547043.BIFPSEUDO_03365 0.0 3721.0 COG4733@1|root,COG4733@2|Bacteria,2GMKC@201174|Actinobacteria,4CZFT@85004|Bifidobacteriales 201174|Actinobacteria S Fibronectin type 3 domain - - - - - - - - - - - - fn3 GGPLMPOG_01717 547043.BIFPSEUDO_03364 6.33e-301 824.0 COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4CZ3M@85004|Bifidobacteriales 201174|Actinobacteria S ATPase family associated with various cellular activities (AAA) - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 GGPLMPOG_01718 547043.BIFPSEUDO_03363 1.1e-280 768.0 COG1721@1|root,COG1721@2|Bacteria,2GIWE@201174|Actinobacteria,4CZWT@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function DUF58 - - - - - - - - - - - - DUF58 GGPLMPOG_01719 547043.BIFPSEUDO_03362 0.0 1582.0 COG1305@1|root,COG1305@2|Bacteria,2HQBB@201174|Actinobacteria,4CZ3X@85004|Bifidobacteriales 201174|Actinobacteria E Transglutaminase-like superfamily - - - - - - - - - - - - Transglut_core GGPLMPOG_01720 547043.BIFPSEUDO_03361 7e-210 580.0 COG0631@1|root,COG0631@2|Bacteria,2GJ3M@201174|Actinobacteria,4CZNH@85004|Bifidobacteriales 201174|Actinobacteria T Sigma factor PP2C-like phosphatases - - 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - BofC_C,PP2C,PP2C_2 GGPLMPOG_01721 547043.BIFPSEUDO_03360 4.63e-150 424.0 COG5602@1|root,COG5602@2|Bacteria,2GRHT@201174|Actinobacteria,4D0W6@85004|Bifidobacteriales 201174|Actinobacteria B Belongs to the OprB family - - - - - - - - - - - - - GGPLMPOG_01722 547043.BIFPSEUDO_03359 5.79e-125 357.0 COG1716@1|root,COG1716@2|Bacteria,2IIXF@201174|Actinobacteria,4D0UU@85004|Bifidobacteriales 201174|Actinobacteria T Forkhead associated domain - - - - - - - - - - - - FHA GGPLMPOG_01723 547043.BIFPSEUDO_03357 0.0 2568.0 COG0086@1|root,COG0086@2|Bacteria,2GKWF@201174|Actinobacteria,4CZ1D@85004|Bifidobacteriales 201174|Actinobacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 GGPLMPOG_01724 547043.BIFPSEUDO_03356 0.0 2359.0 COG0085@1|root,COG0085@2|Bacteria,2GJ81@201174|Actinobacteria,4CZ3W@85004|Bifidobacteriales 201174|Actinobacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB - 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 GGPLMPOG_01725 547043.BIFPSEUDO_03355 1.17e-136 388.0 2EJHA@1|root,33D88@2|Bacteria,2I4ZV@201174|Actinobacteria,4D2XA@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01726 547043.BIFPSEUDO_03353 8.97e-233 640.0 COG1194@1|root,COG1194@2|Bacteria,2GJD9@201174|Actinobacteria,4CYRB@85004|Bifidobacteriales 201174|Actinobacteria L FES mutY GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 - ko:K03575 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD GGPLMPOG_01727 547043.BIFPSEUDO_03354 2.24e-162 454.0 COG0219@1|root,COG0219@2|Bacteria,2IHN9@201174|Actinobacteria,4CZ0E@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily spoU - 2.1.1.207 ko:K03216 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase GGPLMPOG_01728 566552.BIFCAT_01162 0.0 870.0 COG2848@1|root,COG2848@2|Bacteria,2HHMF@201174|Actinobacteria,4CZGB@85004|Bifidobacteriales 201174|Actinobacteria S UPF0210 protein - - - ko:K09157 - - - - ko00000 - - - DUF711 GGPLMPOG_01729 566552.BIFCAT_01163 1.32e-57 178.0 COG3830@1|root,COG3830@2|Bacteria,2IKS1@201174|Actinobacteria,4D11D@85004|Bifidobacteriales 201174|Actinobacteria T Belongs to the UPF0237 family - - - ko:K07166 - - - - ko00000 - - - ACT_6 GGPLMPOG_01730 216816.GS08_02415 0.0 1281.0 COG1621@1|root,COG1621@2|Bacteria,2GJ9T@201174|Actinobacteria,4CZ8W@85004|Bifidobacteriales 201174|Actinobacteria G Belongs to the glycosyl hydrolase 32 family - - 3.2.1.26 ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00801,R00802,R02410,R03635,R03921,R06088 RC00028,RC00077 ko00000,ko00001,ko01000 - GH32 - Glyco_hydro_32N GGPLMPOG_01731 216816.GS08_02410 1.99e-227 630.0 COG1609@1|root,COG1609@2|Bacteria,2GJY9@201174|Actinobacteria,4CYU5@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn _helix lactose operon repressor - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 GGPLMPOG_01732 216816.GS08_02405 2.77e-149 421.0 COG5578@1|root,COG5578@2|Bacteria,2H1AM@201174|Actinobacteria,4CYSQ@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function, DUF624 - - - - - - - - - - - - DUF624 GGPLMPOG_01733 216816.GS08_02400 9.21e-216 596.0 COG0395@1|root,COG0395@2|Bacteria,2GJPQ@201174|Actinobacteria,4CYTJ@85004|Bifidobacteriales 201174|Actinobacteria G Binding-protein-dependent transport system inner membrane component - - - ko:K17320 ko02010,map02010 M00603 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.29,3.A.1.1.9 - - BPD_transp_1 GGPLMPOG_01734 216816.GS08_02395 7.2e-111 325.0 COG4209@1|root,COG4209@2|Bacteria,2GKSR@201174|Actinobacteria,4CZIC@85004|Bifidobacteriales 201174|Actinobacteria G Binding-protein-dependent transport system inner membrane component - - - ko:K17319 ko02010,map02010 M00603 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.29,3.A.1.1.9 - - BPD_transp_1 GGPLMPOG_01735 216816.GS08_02395 2.58e-90 273.0 COG4209@1|root,COG4209@2|Bacteria,2GKSR@201174|Actinobacteria,4CZIC@85004|Bifidobacteriales 201174|Actinobacteria G Binding-protein-dependent transport system inner membrane component - - - ko:K17319 ko02010,map02010 M00603 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.29,3.A.1.1.9 - - BPD_transp_1 GGPLMPOG_01736 216816.GS08_02390 0.0 1060.0 COG1653@1|root,COG1653@2|Bacteria,2I8SG@201174|Actinobacteria,4CZ4S@85004|Bifidobacteriales 201174|Actinobacteria G Bacterial extracellular solute-binding protein - - - ko:K17318 ko02010,map02010 M00603 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.29,3.A.1.1.9 - - SBP_bac_1,SBP_bac_8 GGPLMPOG_01737 547043.BIFPSEUDO_03346 1.45e-297 812.0 COG0153@1|root,COG0153@2|Bacteria,2GJXI@201174|Actinobacteria,4CZNV@85004|Bifidobacteriales 201174|Actinobacteria G Belongs to the GHMP kinase family. GalK subfamily galK - 2.7.1.6,2.7.7.12 ko:K00849,ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955,R01092 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko04147 - - - GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg GGPLMPOG_01738 566552.BIFCAT_01165 9.99e-317 861.0 COG1085@1|root,COG1085@2|Bacteria,2I2DM@201174|Actinobacteria,4CYXZ@85004|Bifidobacteriales 201174|Actinobacteria C Galactose-1-phosphate uridyl transferase, N-terminal domain galT - 2.7.7.12 ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955 RC00002 ko00000,ko00001,ko00002,ko01000 - - - GalP_UDP_tr_C,GalP_UDP_transf GGPLMPOG_01739 1680.BADO_1393 1.13e-181 507.0 COG1349@1|root,COG1349@2|Bacteria,2H5X4@201174|Actinobacteria,4CZMT@85004|Bifidobacteriales 201174|Actinobacteria K DeoR C terminal sensor domain - - - - - - - - - - - - DeoRC,HTH_DeoR GGPLMPOG_01740 547043.BIFPSEUDO_03342 1.41e-289 789.0 COG0167@1|root,COG0167@2|Bacteria,2GKC6@201174|Actinobacteria,4CYWW@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor pyrD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.3.5.2,1.3.98.1 ko:K00226,ko:K00254 ko00240,ko01100,map00240,map01100 M00051 R01867,R01868 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh GGPLMPOG_01741 547043.BIFPSEUDO_03341 4.15e-280 764.0 COG1902@1|root,COG1902@2|Bacteria,2GK8E@201174|Actinobacteria,4CZ9Z@85004|Bifidobacteriales 201174|Actinobacteria C NADH:flavin oxidoreductase / NADH oxidase family namA - - - - - - - - - - - Oxidored_FMN GGPLMPOG_01742 547043.BIFPSEUDO_03339 0.0 1447.0 COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria,4CZAZ@85004|Bifidobacteriales 201174|Actinobacteria M Transglycosylase pon1 - - - - - - - - - - - PASTA,Transgly,Transpeptidase GGPLMPOG_01743 547043.BIFPSEUDO_03338 8.67e-170 474.0 COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria,4CYYW@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn_helix, cAMP Regulatory protein crp - - ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - HTH_Crp_2,cNMP_binding GGPLMPOG_01744 547043.BIFPSEUDO_03337 2.89e-272 745.0 COG0095@1|root,COG0095@2|Bacteria,2GJV5@201174|Actinobacteria,4CZYA@85004|Bifidobacteriales 201174|Actinobacteria H Biotin/lipoate A/B protein ligase family lplA - 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 - R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB GGPLMPOG_01745 547043.BIFPSEUDO_03336 2.42e-131 377.0 COG2314@1|root,COG2314@2|Bacteria,2IQB3@201174|Actinobacteria,4D11Z@85004|Bifidobacteriales 201174|Actinobacteria J TM2 domain - - - - - - - - - - - - TM2 GGPLMPOG_01746 547043.BIFPSEUDO_03334 9.62e-247 677.0 COG0473@1|root,COG0473@2|Bacteria,2GK44@201174|Actinobacteria,4CZ08@85004|Bifidobacteriales 201174|Actinobacteria CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate leuB GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh GGPLMPOG_01747 547043.BIFPSEUDO_03333 0.0 1727.0 COG1770@1|root,COG1770@2|Bacteria,2GNA9@201174|Actinobacteria,4CZ2X@85004|Bifidobacteriales 201174|Actinobacteria E Peptidase, S9A B C family, catalytic domain protein ptrB - 3.4.21.83 ko:K01354 ko05142,ko05143,map05142,map05143 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S9,Peptidase_S9_N GGPLMPOG_01748 547043.BIFPSEUDO_03332 2.93e-299 816.0 COG4850@1|root,COG4850@2|Bacteria,2GKPS@201174|Actinobacteria,4CZ13@85004|Bifidobacteriales 201174|Actinobacteria S Uncharacterized conserved protein (DUF2183) - - - - - - - - - - - - DUF2183 GGPLMPOG_01749 547043.BIFPSEUDO_03331 1.66e-92 270.0 COG0509@1|root,COG0509@2|Bacteria,2IKN2@201174|Actinobacteria,4D0W7@85004|Bifidobacteriales 201174|Actinobacteria E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein gcvH - - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - - GCV_H GGPLMPOG_01750 547043.BIFPSEUDO_03330 1.26e-266 729.0 COG2816@1|root,COG2816@2|Bacteria,2GJZY@201174|Actinobacteria,4CZE5@85004|Bifidobacteriales 201174|Actinobacteria L NADH pyrophosphatase zinc ribbon domain nudC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.1.22 ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 - R00103,R03004,R11104 RC00002 ko00000,ko00001,ko01000 - - - NUDIX,NUDIX-like,zf-NADH-PPase GGPLMPOG_01751 547043.BIFPSEUDO_03329 2.25e-206 570.0 COG2267@1|root,COG2267@2|Bacteria,2I2GI@201174|Actinobacteria,4CYXW@85004|Bifidobacteriales 201174|Actinobacteria I Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 GGPLMPOG_01752 547043.BIFPSEUDO_03327 1.95e-147 415.0 COG1051@1|root,COG1051@2|Bacteria,2GJGZ@201174|Actinobacteria,4CYT1@85004|Bifidobacteriales 201174|Actinobacteria F Domain of unknown function (DUF4916) - - - - - - - - - - - - DUF4916 GGPLMPOG_01753 547043.BIFPSEUDO_03326 4.09e-80 238.0 COG0526@1|root,COG0526@2|Bacteria,2IKP1@201174|Actinobacteria,4D11J@85004|Bifidobacteriales 201174|Actinobacteria O Belongs to the thioredoxin family trxA - 1.8.1.9 ko:K00384,ko:K03671 ko00450,ko04621,ko05418,map00450,map04621,map05418 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000,ko03110 - - - Thioredoxin GGPLMPOG_01754 547043.BIFPSEUDO_03324 8.25e-225 621.0 COG3583@1|root,COG3583@2|Bacteria,2I2GH@201174|Actinobacteria,4CYVC@85004|Bifidobacteriales 201174|Actinobacteria S G5 - - - ko:K21688 - - - - ko00000 - - - DUF348,G5,SLT GGPLMPOG_01755 547043.BIFPSEUDO_03323 8.53e-115 329.0 28PY9@1|root,2ZCI0@2|Bacteria,2INBV@201174|Actinobacteria,4D13Q@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01756 547043.BIFPSEUDO_03321 0.0 1986.0 COG0366@1|root,COG0366@2|Bacteria,2GM4Q@201174|Actinobacteria,4CYYI@85004|Bifidobacteriales 201174|Actinobacteria G Belongs to the glycosyl hydrolase 13 family - - 3.2.1.1 ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 - R02108,R02112,R11262 - ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,Big_2,CBM26,CBM_20,CBM_25,SLH GGPLMPOG_01757 547043.BIFPSEUDO_03320 9.5e-285 777.0 COG1143@1|root,COG1143@2|Bacteria,2I42G@201174|Actinobacteria,4D2WE@85004|Bifidobacteriales 201174|Actinobacteria C Polysaccharide pyruvyl transferase - - - - - - - - - - - - PS_pyruv_trans GGPLMPOG_01758 547043.BIFPSEUDO_03319 2.94e-262 718.0 COG1215@1|root,COG1215@2|Bacteria,2IPTK@201174|Actinobacteria,4D12W@85004|Bifidobacteriales 201174|Actinobacteria M Glycosyltransferase like family 2 - - - ko:K19427 - - - - ko00000,ko01000 - GT2 - Glycos_transf_2 GGPLMPOG_01759 547043.BIFPSEUDO_03318 3.81e-254 696.0 COG0778@1|root,COG0778@2|Bacteria,2IE9H@201174|Actinobacteria,4CZI3@85004|Bifidobacteriales 201174|Actinobacteria C Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - Nitroreductase GGPLMPOG_01760 547043.BIFPSEUDO_03317 5.07e-262 717.0 COG0438@1|root,COG0438@2|Bacteria,2IEFR@201174|Actinobacteria,4CZQH@85004|Bifidobacteriales 201174|Actinobacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - - GGPLMPOG_01761 547043.BIFPSEUDO_03316 0.0 982.0 COG2244@1|root,COG2244@2|Bacteria,2IA1K@201174|Actinobacteria,4D0KU@85004|Bifidobacteriales 201174|Actinobacteria S Psort location CytoplasmicMembrane, score 9.99 - - - - - - - - - - - - Polysacc_synt,Polysacc_synt_C GGPLMPOG_01762 547043.BIFPSEUDO_03315 0.0 882.0 2CCRF@1|root,334T0@2|Bacteria,2H3I4@201174|Actinobacteria,4D23V@85004|Bifidobacteriales 201174|Actinobacteria S Psort location CytoplasmicMembrane, score 9.99 - - - - - - - - - - - - - GGPLMPOG_01763 547043.BIFPSEUDO_03314 6.47e-242 664.0 COG0463@1|root,COG0463@2|Bacteria,2I2GT@201174|Actinobacteria,4D2Y3@85004|Bifidobacteriales 201174|Actinobacteria M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 GGPLMPOG_01764 547043.BIFPSEUDO_03313 2.72e-203 561.0 COG1442@1|root,COG1442@2|Bacteria,2HFT7@201174|Actinobacteria,4CZBS@85004|Bifidobacteriales 201174|Actinobacteria M Domain of unknown function (DUF4422) - - - - - - - - - - - - DUF4422 GGPLMPOG_01765 547043.BIFPSEUDO_03311 1.57e-51 180.0 COG0366@1|root,COG0366@2|Bacteria,2GM4Q@201174|Actinobacteria,4CYYI@85004|Bifidobacteriales 201174|Actinobacteria G Belongs to the glycosyl hydrolase 13 family - - 3.2.1.1 ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 - R02108,R02112,R11262 - ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,Big_2,CBM26,CBM_20,CBM_25,SLH GGPLMPOG_01766 547043.BIFPSEUDO_02544 3.36e-55 172.0 2EG1H@1|root,339TH@2|Bacteria,2IQTR@201174|Actinobacteria,4D16E@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - DUF2530 GGPLMPOG_01767 547043.BIFPSEUDO_02543 5.66e-279 762.0 COG1932@1|root,COG1932@2|Bacteria,2GKYK@201174|Actinobacteria,4CZ94@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine serC GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005886,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0040007,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 GGPLMPOG_01768 547043.BIFPSEUDO_02542 5.96e-213 589.0 COG3942@1|root,COG3942@2|Bacteria,2GP2A@201174|Actinobacteria,4CYXV@85004|Bifidobacteriales 201174|Actinobacteria S CHAP domain - - - - - - - - - - - - CHAP GGPLMPOG_01769 547043.BIFPSEUDO_02540 2.31e-121 351.0 COG0791@1|root,COG0791@2|Bacteria,2GJX7@201174|Actinobacteria,4D01Q@85004|Bifidobacteriales 201174|Actinobacteria M NlpC/P60 family - - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - NLPC_P60,PG_binding_1,SLT GGPLMPOG_01770 547043.BIFPSEUDO_02539 1.53e-242 667.0 COG0589@1|root,COG0589@2|Bacteria,2GMFE@201174|Actinobacteria,4CZ6V@85004|Bifidobacteriales 201174|Actinobacteria T Universal stress protein family - - - - - - - - - - - - Usp GGPLMPOG_01771 547043.BIFPSEUDO_02538 7.52e-95 276.0 COG1765@1|root,COG1765@2|Bacteria,2IIK7@201174|Actinobacteria,4D0PB@85004|Bifidobacteriales 201174|Actinobacteria O OsmC-like protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - OsmC GGPLMPOG_01772 547043.BIFPSEUDO_02537 2.4e-232 637.0 COG0207@1|root,COG0207@2|Bacteria,2GKY0@201174|Actinobacteria,4CZQ3@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009125,GO:0009129,GO:0009130,GO:0009131,GO:0009157,GO:0009159,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009178,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0032259,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042083,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046073,GO:0046078,GO:0046079,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt GGPLMPOG_01773 547043.BIFPSEUDO_02536 1.4e-165 462.0 COG0262@1|root,COG0262@2|Bacteria,2IM1S@201174|Actinobacteria,4CZM1@85004|Bifidobacteriales 201174|Actinobacteria H dihydrofolate reductase folA GO:0000166,GO:0003674,GO:0003824,GO:0004146,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0070401,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.3 ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv2763c DHFR_1 GGPLMPOG_01774 1435051.BMOU_1806 1.21e-109 316.0 COG0394@1|root,COG0394@2|Bacteria,2IM0Q@201174|Actinobacteria,4CZWM@85004|Bifidobacteriales 201174|Actinobacteria T low molecular weight ptpA GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009405,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0035335,GO:0035821,GO:0036211,GO:0042578,GO:0043170,GO:0043207,GO:0043412,GO:0044003,GO:0044046,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052046,GO:0052047,GO:0052048,GO:0052083,GO:0052155,GO:0052173,GO:0052200,GO:0052212,GO:0052255,GO:0052278,GO:0052294,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0071704,GO:0071944,GO:0075136,GO:0140096,GO:1901564 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - LMWPc GGPLMPOG_01776 547043.BIFPSEUDO_02532 3.01e-254 696.0 COG1087@1|root,COG1087@2|Bacteria,2GMCW@201174|Actinobacteria,4CZDB@85004|Bifidobacteriales 201174|Actinobacteria M Belongs to the NAD(P)-dependent epimerase dehydratase family galE - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase GGPLMPOG_01777 547043.BIFPSEUDO_02531 1.54e-216 597.0 COG0220@1|root,COG0220@2|Bacteria,2GJ8R@201174|Actinobacteria,4CZKF@85004|Bifidobacteriales 201174|Actinobacteria J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 ko:K03439 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_4 GGPLMPOG_01781 547043.BIFPSEUDO_02526 0.0 1426.0 COG0451@1|root,COG0451@2|Bacteria,2ICHN@201174|Actinobacteria,4CYZ7@85004|Bifidobacteriales 201174|Actinobacteria GM ADP-glyceromanno-heptose 6-epimerase activity - - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase GGPLMPOG_01782 547043.BIFPSEUDO_02525 8.5e-213 588.0 28H6W@1|root,2Z7J7@2|Bacteria,2ICGP@201174|Actinobacteria,4CZUA@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01783 547043.BIFPSEUDO_02524 0.0 1252.0 COG4878@1|root,COG4878@2|Bacteria,2IERA@201174|Actinobacteria,4D00K@85004|Bifidobacteriales 201174|Actinobacteria S Uncharacterised protein conserved in bacteria (DUF2194) - - - - - - - - - - - - DUF2194 GGPLMPOG_01784 547043.BIFPSEUDO_02523 0.0 974.0 COG0438@1|root,COG0438@2|Bacteria,2GKEA@201174|Actinobacteria,4CZ5G@85004|Bifidobacteriales 201174|Actinobacteria M Domain of unknown function (DUF3492) - - - ko:K21011 ko02025,map02025 - - - ko00000,ko00001,ko01003 - GT4 - DUF3492,Glyco_trans_1_4,Glycos_transf_1 GGPLMPOG_01785 547043.BIFPSEUDO_02522 0.0 979.0 COG4267@1|root,COG4267@2|Bacteria,2IE76@201174|Actinobacteria,4CZ7D@85004|Bifidobacteriales 201174|Actinobacteria S Putative exopolysaccharide Exporter (EPS-E) - - - ko:K21012 ko02025,map02025 - - - ko00000,ko00001 - - - PelG GGPLMPOG_01786 547043.BIFPSEUDO_02521 0.0 1155.0 COG5337@1|root,COG5337@2|Bacteria,2ID5Z@201174|Actinobacteria,4D02F@85004|Bifidobacteriales 201174|Actinobacteria M CotH kinase protein - - - ko:K06330 - - - - ko00000 - - - CotH GGPLMPOG_01787 547043.BIFPSEUDO_02520 2.74e-203 561.0 COG5036@1|root,COG5036@2|Bacteria,2HZIY@201174|Actinobacteria,4D0MA@85004|Bifidobacteriales 201174|Actinobacteria P VTC domain - - - - - - - - - - - - VTC GGPLMPOG_01788 547043.BIFPSEUDO_02519 4.21e-143 405.0 COG1285@1|root,COG1285@2|Bacteria,2HZFV@201174|Actinobacteria,4D0AX@85004|Bifidobacteriales 201174|Actinobacteria S Domain of unknown function (DUF4956) - - - - - - - - - - - - DUF4956 GGPLMPOG_01789 547043.BIFPSEUDO_02518 0.0 1461.0 COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,2I2FR@201174|Actinobacteria,4D09B@85004|Bifidobacteriales 201174|Actinobacteria T Putative diguanylate phosphodiesterase - - 3.1.4.52 ko:K14051 ko02024,ko02026,map02024,map02026 - - - ko00000,ko00001,ko01000 - - - EAL,GGDEF,PAS,PAS_3,PAS_4 GGPLMPOG_01790 547043.BIFPSEUDO_02517 1.73e-270 742.0 COG1454@1|root,COG1454@2|Bacteria,2I2FD@201174|Actinobacteria,4CZ71@85004|Bifidobacteriales 201174|Actinobacteria C Iron-containing alcohol dehydrogenase fucO - 1.1.1.77,1.1.99.37,1.2.98.1 ko:K00048,ko:K17067 ko00625,ko00630,ko00640,ko00680,ko01120,ko01200,map00625,map00630,map00640,map00680,map01120,map01200 - R00614,R01781,R02257 RC00034,RC00087,RC00099,RC00188 ko00000,ko00001,ko01000 - - - Fe-ADH GGPLMPOG_01791 547043.BIFPSEUDO_02515 3.15e-230 632.0 COG1215@1|root,COG1215@2|Bacteria,2GNPU@201174|Actinobacteria,4CZ7E@85004|Bifidobacteriales 201174|Actinobacteria M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 GGPLMPOG_01792 547043.BIFPSEUDO_02514 0.0 894.0 COG0628@1|root,COG0628@2|Bacteria,2GN4Y@201174|Actinobacteria,4CZD1@85004|Bifidobacteriales 201174|Actinobacteria S AI-2E family transporter - - - - - - - - - - - - AI-2E_transport GGPLMPOG_01793 547043.BIFPSEUDO_02513 9.34e-294 801.0 COG1215@1|root,COG1215@2|Bacteria,2HZ9V@201174|Actinobacteria,4CZ5J@85004|Bifidobacteriales 201174|Actinobacteria M Glycosyl transferase family 21 - - - - - - - - - - - - Glyco_tranf_2_3 GGPLMPOG_01794 547043.BIFPSEUDO_02512 9.19e-295 810.0 COG2027@1|root,COG2027@2|Bacteria,2GJPH@201174|Actinobacteria,4CYXQ@85004|Bifidobacteriales 201174|Actinobacteria M D-Ala-D-Ala carboxypeptidase 3 (S13) family dacB - 3.4.16.4 ko:K07259 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - Peptidase_S13 GGPLMPOG_01795 566552.BIFCAT_01322 1.14e-254 699.0 COG0037@1|root,COG0037@2|Bacteria,2GJR4@201174|Actinobacteria,4CYSY@85004|Bifidobacteriales 201174|Actinobacteria J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine tilS GO:0008150,GO:0040007 2.4.2.8,6.3.4.19 ko:K00760,ko:K04075 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 - R00190,R01132,R01229,R02142,R08237,R08238,R08245,R09597 RC00063,RC00122,RC02633,RC02634 ko00000,ko00001,ko01000,ko03016 - - - ATP_bind_3,TilS GGPLMPOG_01796 547043.BIFPSEUDO_02510 1.72e-128 365.0 COG0634@1|root,COG0634@2|Bacteria,2GMDZ@201174|Actinobacteria,4CZNJ@85004|Bifidobacteriales 201174|Actinobacteria F Belongs to the purine pyrimidine phosphoribosyltransferase family hpt - 2.4.2.8 ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 - R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000 - - - Pribosyltran GGPLMPOG_01797 547043.BIFPSEUDO_02509 0.0 1330.0 COG0465@1|root,COG0465@2|Bacteria,2GJ4Q@201174|Actinobacteria,4CZ6U@85004|Bifidobacteriales 201174|Actinobacteria O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0019538,GO:0030163,GO:0040007,GO:0042623,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 GGPLMPOG_01798 547043.BIFPSEUDO_02508 2.51e-150 422.0 COG0302@1|root,COG0302@2|Bacteria,2GP2P@201174|Actinobacteria,4CZ5S@85004|Bifidobacteriales 201174|Actinobacteria H GTP cyclohydrolase folE GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv3609c GTP_cyclohydroI GGPLMPOG_01799 547043.BIFPSEUDO_02507 2.16e-203 563.0 COG0294@1|root,COG0294@2|Bacteria,2GJDQ@201174|Actinobacteria,4CZWW@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives folP GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 ko:K00796 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 - - - Pterin_bind GGPLMPOG_01800 566552.BIFCAT_01327 0.0 992.0 COG0801@1|root,COG1539@1|root,COG0801@2|Bacteria,COG1539@2|Bacteria,2H3G6@201174|Actinobacteria,4D0EJ@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin folK - 2.7.6.3,4.1.2.25 ko:K00950,ko:K13940 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503,R03504 RC00002,RC00017,RC00721,RC00943 ko00000,ko00001,ko00002,ko01000 - - - FolB,HPPK GGPLMPOG_01801 547043.BIFPSEUDO_02505 1.38e-126 360.0 2DRQG@1|root,33CMQ@2|Bacteria,2HZP6@201174|Actinobacteria,4D14M@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF3180) - - - - - - - - - - - - DUF3180 GGPLMPOG_01802 547043.BIFPSEUDO_02504 1.53e-215 595.0 COG1946@1|root,COG1946@2|Bacteria,2GJ1B@201174|Actinobacteria,4CZRC@85004|Bifidobacteriales 201174|Actinobacteria I Thioesterase-like superfamily tesB - - ko:K10805 ko01040,map01040 - - - ko00000,ko00001,ko01000,ko01004 - - - 4HBT_3 GGPLMPOG_01803 566552.BIFCAT_01330 0.0 1111.0 COG0488@1|root,COG0488@2|Bacteria,2GKBQ@201174|Actinobacteria,4CYWH@85004|Bifidobacteriales 201174|Actinobacteria S ATP-binding cassette protein, ChvD family yjjK GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - - - - - - - - - - ABC_tran,ABC_tran_Xtn GGPLMPOG_01804 1437610.BREU_1647 1.9e-231 635.0 COG1680@1|root,COG1680@2|Bacteria,2GK3A@201174|Actinobacteria,4D06I@85004|Bifidobacteriales 201174|Actinobacteria V Beta-lactamase - - - - - - - - - - - - Beta-lactamase GGPLMPOG_01805 1437610.BREU_1646 7.43e-97 281.0 COG0242@1|root,COG0242@2|Bacteria,2IJQ5@201174|Actinobacteria,4D14S@85004|Bifidobacteriales 201174|Actinobacteria J Removes the formyl group from the N-terminal Met of newly synthesized proteins fms - 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase GGPLMPOG_01806 547043.BIFPSEUDO_02499 1.12e-126 360.0 COG0117@1|root,COG0117@2|Bacteria,2IFMN@201174|Actinobacteria,4D0JA@85004|Bifidobacteriales 201174|Actinobacteria H Cytidine and deoxycytidylate deaminase zinc-binding region - - 1.1.1.193,3.5.4.26 ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 - - - RibD_C,dCMP_cyt_deam_1 GGPLMPOG_01807 1437610.BREU_1644 0.0 882.0 COG1653@1|root,COG1653@2|Bacteria,2GP9H@201174|Actinobacteria,4D01H@85004|Bifidobacteriales 201174|Actinobacteria G ABC transporter periplasmic binding protein YcjN precursor K02027 - - - ko:K17326 ko02010,map02010 M00619 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.21 - - SBP_bac_1,SBP_bac_8 GGPLMPOG_01808 547043.BIFPSEUDO_02497 5.2e-225 620.0 COG1175@1|root,COG1175@2|Bacteria,2GJ32@201174|Actinobacteria,4D0SM@85004|Bifidobacteriales 201174|Actinobacteria U Binding-protein-dependent transport system inner membrane component - - - ko:K17327 ko02010,map02010 M00619 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.21 - - BPD_transp_1 GGPLMPOG_01809 1437610.BREU_1642 9.32e-193 536.0 COG0395@1|root,COG0395@2|Bacteria,2GM2W@201174|Actinobacteria,4D0U9@85004|Bifidobacteriales 201174|Actinobacteria G Binding-protein-dependent transport system inner membrane component - - - ko:K17328 ko02010,map02010 M00619 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.21 - - BPD_transp_1 GGPLMPOG_01810 1437610.BREU_1641 0.0 1418.0 COG1653@1|root,COG1653@2|Bacteria,2HT29@201174|Actinobacteria,4CZ28@85004|Bifidobacteriales 201174|Actinobacteria G Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - Beta_helix,DUF1565 GGPLMPOG_01811 1437610.BREU_1640 0.0 1159.0 COG3507@1|root,COG3507@2|Bacteria,2GIW3@201174|Actinobacteria,4CZ5I@85004|Bifidobacteriales 201174|Actinobacteria G Belongs to the glycosyl hydrolase 43 family - - 3.2.1.37 ko:K01198 ko00520,ko01100,map00520,map01100 - R01433 RC00467 ko00000,ko00001,ko01000 - GH43 - Glyco_hydro_43 GGPLMPOG_01812 1437610.BREU_1639 0.0 1479.0 COG1331@1|root,COG1331@2|Bacteria,2I94Q@201174|Actinobacteria,4D1VW@85004|Bifidobacteriales 201174|Actinobacteria O Highly conserved protein containing a thioredoxin domain - - - - - - - - - - - - - GGPLMPOG_01813 547043.BIFPSEUDO_02492 1.25e-298 811.0 COG3405@1|root,COG3405@2|Bacteria,2IA68@201174|Actinobacteria,4CZYP@85004|Bifidobacteriales 201174|Actinobacteria G CBM9 module, glycoside hydrolase family 8 protein and carbohydrate esterase family 4 protein K01238 - - 3.2.1.156 ko:K15531 - - - - ko00000,ko01000 - GH8 - Glyco_hydro_8 GGPLMPOG_01814 547043.BIFPSEUDO_02491 0.0 1308.0 COG3250@1|root,COG3250@2|Bacteria,2ICNG@201174|Actinobacteria,4CZQA@85004|Bifidobacteriales 201174|Actinobacteria G Glycosyl hydrolase family 2, sugar binding domain protein - - 3.1.1.53 ko:K05970 - - - - ko00000,ko01000 - - - SASA GGPLMPOG_01815 1437600.JDUI01000015_gene1073 8.49e-12 65.1 COG1979@1|root,COG1979@2|Bacteria,2IAN0@201174|Actinobacteria,4D02T@85004|Bifidobacteriales 201174|Actinobacteria C Iron-containing alcohol dehydrogenase - - - - - - - - - - - - Fe-ADH GGPLMPOG_01816 547043.BIFPSEUDO_02490 4.43e-274 748.0 COG1979@1|root,COG1979@2|Bacteria,2IAN0@201174|Actinobacteria,4D02T@85004|Bifidobacteriales 201174|Actinobacteria C Iron-containing alcohol dehydrogenase - - - - - - - - - - - - Fe-ADH GGPLMPOG_01817 547043.BIFPSEUDO_02487 8.24e-217 598.0 COG1957@1|root,COG1957@2|Bacteria,2IGHG@201174|Actinobacteria,4D0I0@85004|Bifidobacteriales 201174|Actinobacteria F Inosine-uridine preferring nucleoside hydrolase - - - - - - - - - - - - IU_nuc_hydro GGPLMPOG_01818 547043.BIFPSEUDO_02486 0.0 1009.0 COG1070@1|root,COG1070@2|Bacteria,2GJDZ@201174|Actinobacteria,4CZH0@85004|Bifidobacteriales 201174|Actinobacteria G FGGY family of carbohydrate kinases, C-terminal domain xylB - 2.7.1.17 ko:K00854 ko00040,ko01100,map00040,map01100 M00014 R01639 RC00002,RC00538 ko00000,ko00001,ko00002,ko01000 - - - FGGY_C,FGGY_N GGPLMPOG_01819 1437610.BREU_1633 5.36e-289 790.0 COG1940@1|root,COG1940@2|Bacteria,2GJIE@201174|Actinobacteria,4CZPD@85004|Bifidobacteriales 201174|Actinobacteria GK ROK family xylR - - - - - - - - - - - HTH_IclR,MarR_2,ROK GGPLMPOG_01820 547043.BIFPSEUDO_02483 4.68e-80 238.0 COG4721@1|root,COG4721@2|Bacteria,2H5VZ@201174|Actinobacteria,4CZ6M@85004|Bifidobacteriales 201174|Actinobacteria S ABC-type cobalt transport system, permease component - - - ko:K16925 - M00582 - - ko00000,ko00002,ko02000 3.A.1.30 - - ABC_cobalt GGPLMPOG_01821 547043.BIFPSEUDO_02481 1.27e-169 474.0 COG3238@1|root,COG3238@2|Bacteria,2IB1U@201174|Actinobacteria,4D0GN@85004|Bifidobacteriales 201174|Actinobacteria S Putative inner membrane exporter, YdcZ - - - ko:K09936 ko02024,map02024 - - - ko00000,ko00001,ko02000 2.A.7.21 - - DMT_YdcZ GGPLMPOG_01822 547043.BIFPSEUDO_02480 1.43e-137 392.0 COG2364@1|root,COG2364@2|Bacteria,2IADD@201174|Actinobacteria,4D0K2@85004|Bifidobacteriales 201174|Actinobacteria S Membrane - - - ko:K07149 - - - - ko00000 - - - - GGPLMPOG_01823 547043.BIFPSEUDO_02479 0.0 961.0 COG2865@1|root,COG2865@2|Bacteria,2GZ30@201174|Actinobacteria,4CYSX@85004|Bifidobacteriales 201174|Actinobacteria K Putative ATP-dependent DNA helicase recG C-terminal - - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AlbA_2,HATPase_c_4,HTH_24,HTH_5 GGPLMPOG_01824 566552.BIFCAT_01336 5.6e-316 860.0 COG2873@1|root,COG2873@2|Bacteria,2I2EB@201174|Actinobacteria,4CYSA@85004|Bifidobacteriales 201174|Actinobacteria H Psort location Cytoplasmic, score 9.98 - - 2.5.1.49 ko:K01740 ko00270,ko01100,map00270,map01100 - R01287,R04859 RC00020,RC02821,RC02848 ko00000,ko00001,ko01000 - - - Cys_Met_Meta_PP GGPLMPOG_01825 547043.BIFPSEUDO_02477 0.0 923.0 COG2115@1|root,COG2115@2|Bacteria,2GJCA@201174|Actinobacteria,4CZK8@85004|Bifidobacteriales 201174|Actinobacteria G Belongs to the xylose isomerase family xylA - 5.3.1.5 ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 - R00878,R01432 RC00376,RC00516 ko00000,ko00001,ko01000 - - - AP_endonuc_2 GGPLMPOG_01826 547043.BIFPSEUDO_02475 0.0 1178.0 COG3507@1|root,COG3507@2|Bacteria,2GIW3@201174|Actinobacteria,4CZY8@85004|Bifidobacteriales 201174|Actinobacteria G Belongs to the glycosyl hydrolase 43 family - - 3.2.1.37,3.2.1.55 ko:K01198,ko:K01209 ko00520,ko01100,map00520,map01100 - R01433,R01762 RC00467 ko00000,ko00001,ko01000 - GH43,GH51 - Glyco_hydro_43 GGPLMPOG_01827 547043.BIFPSEUDO_02474 5.93e-237 652.0 COG1609@1|root,COG1609@2|Bacteria,2GJRG@201174|Actinobacteria,4CZI0@85004|Bifidobacteriales 201174|Actinobacteria K Bacterial regulatory proteins, lacI family - - - ko:K02529,ko:K17640 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 GGPLMPOG_01828 547043.BIFPSEUDO_02473 4.08e-308 839.0 COG1653@1|root,COG1653@2|Bacteria,2GP9H@201174|Actinobacteria,4D01H@85004|Bifidobacteriales 201174|Actinobacteria G ABC transporter periplasmic binding protein YcjN precursor K02027 - - - ko:K02027,ko:K10117 ko02010,map02010 M00196,M00207 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.28 - - SBP_bac_1,SBP_bac_8 GGPLMPOG_01829 547043.BIFPSEUDO_02472 8.4e-237 652.0 COG1175@1|root,COG1175@2|Bacteria,2GKJI@201174|Actinobacteria,4CZQU@85004|Bifidobacteriales 201174|Actinobacteria U Binding-protein-dependent transport system inner membrane component - - - ko:K02025,ko:K10118 ko02010,map02010 M00196,M00207 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.28 - - BPD_transp_1 GGPLMPOG_01830 547043.BIFPSEUDO_02471 4.06e-212 586.0 COG0395@1|root,COG0395@2|Bacteria,2GNQW@201174|Actinobacteria,4CZTW@85004|Bifidobacteriales 201174|Actinobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02026,ko:K10119,ko:K17243 ko02010,map02010 M00196,M00207,M00600 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.28,3.A.1.1.39 - - BPD_transp_1 GGPLMPOG_01831 547043.BIFPSEUDO_02470 0.0 1166.0 COG3507@1|root,COG3507@2|Bacteria,2GIW3@201174|Actinobacteria,4CZ5I@85004|Bifidobacteriales 201174|Actinobacteria G Belongs to the glycosyl hydrolase 43 family - - 3.2.1.37 ko:K01198 ko00520,ko01100,map00520,map01100 - R01433 RC00467 ko00000,ko00001,ko01000 - GH43 - Glyco_hydro_43 GGPLMPOG_01832 547043.BIFPSEUDO_02469 0.0 1389.0 COG3250@1|root,COG3250@2|Bacteria,2ICNG@201174|Actinobacteria,4CZQA@85004|Bifidobacteriales 201174|Actinobacteria G Glycosyl hydrolase family 2, sugar binding domain protein - - 3.1.1.53 ko:K05970 - - - - ko00000,ko01000 - - - SASA GGPLMPOG_01833 1680.BADO_0435 3.07e-11 63.2 COG2272@1|root,COG2272@2|Bacteria,2GJCN@201174|Actinobacteria,4D02Y@85004|Bifidobacteriales 201174|Actinobacteria I Belongs to the type-B carboxylesterase lipase family - - - ko:K03929 - - - - ko00000,ko01000 - CE10 - COesterase GGPLMPOG_01834 547043.BIFPSEUDO_02467 2.08e-143 405.0 COG0110@1|root,COG0110@2|Bacteria,2GNUB@201174|Actinobacteria,4CZ5K@85004|Bifidobacteriales 201174|Actinobacteria S Bacterial transferase hexapeptide repeat protein maa - 2.3.1.18,2.3.1.79 ko:K00633,ko:K00661 - - - - ko00000,ko01000 - - - Hexapep,Hexapep_2,Mac GGPLMPOG_01835 547043.BIFPSEUDO_02466 0.0 995.0 COG1070@1|root,COG1070@2|Bacteria,2GJDZ@201174|Actinobacteria,4CZH0@85004|Bifidobacteriales 201174|Actinobacteria G FGGY family of carbohydrate kinases, C-terminal domain xylB - 2.7.1.17 ko:K00854 ko00040,ko01100,map00040,map01100 M00014 R01639 RC00002,RC00538 ko00000,ko00001,ko00002,ko01000 - - - FGGY_C,FGGY_N GGPLMPOG_01836 547043.BIFPSEUDO_02465 4.92e-285 780.0 COG1940@1|root,COG1940@2|Bacteria,2GJIE@201174|Actinobacteria,4CZPD@85004|Bifidobacteriales 201174|Actinobacteria GK ROK family xylR - - - - - - - - - - - HTH_IclR,MarR_2,ROK GGPLMPOG_01838 547043.BIFPSEUDO_02463 2.63e-48 153.0 COG0254@1|root,COG0254@2|Bacteria,2IQ4I@201174|Actinobacteria,4D17F@85004|Bifidobacteriales 201174|Actinobacteria J Binds the 23S rRNA rpmE GO:0008150,GO:0040007 - ko:K02909 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L31 GGPLMPOG_01839 547043.BIFPSEUDO_02461 3.2e-244 672.0 COG0216@1|root,COG0216@2|Bacteria,2GJWG@201174|Actinobacteria,4CYX4@85004|Bifidobacteriales 201174|Actinobacteria J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA GO:0008150,GO:0040007 - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 GGPLMPOG_01840 547043.BIFPSEUDO_02460 7.35e-220 606.0 COG2890@1|root,COG2890@2|Bacteria,2GMH1@201174|Actinobacteria,4CZB3@85004|Bifidobacteriales 201174|Actinobacteria J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif prmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 ko:K02493 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03012 - - - MTS,Methyltransf_25,Methyltransf_31 GGPLMPOG_01841 547043.BIFPSEUDO_02459 2.76e-278 762.0 COG0683@1|root,COG0683@2|Bacteria,2GM00@201174|Actinobacteria,4CZYU@85004|Bifidobacteriales 201174|Actinobacteria E Receptor family ligand binding region - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 GGPLMPOG_01842 547043.BIFPSEUDO_02458 8.89e-199 553.0 COG0559@1|root,COG0559@2|Bacteria,2GMAY@201174|Actinobacteria,4CZQ6@85004|Bifidobacteriales 201174|Actinobacteria U Belongs to the binding-protein-dependent transport system permease family - - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 GGPLMPOG_01843 547043.BIFPSEUDO_02457 3.09e-249 686.0 COG4177@1|root,COG4177@2|Bacteria,2GJB3@201174|Actinobacteria,4CYTE@85004|Bifidobacteriales 201174|Actinobacteria U Belongs to the binding-protein-dependent transport system permease family - - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 GGPLMPOG_01844 547043.BIFPSEUDO_02456 1.19e-192 535.0 COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,4CZBX@85004|Bifidobacteriales 201174|Actinobacteria E Branched-chain amino acid ATP-binding cassette transporter livG - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C GGPLMPOG_01845 547043.BIFPSEUDO_02455 8.3e-160 448.0 COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria,4CZE0@85004|Bifidobacteriales 201174|Actinobacteria E ATPases associated with a variety of cellular activities livF - - ko:K01995,ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C GGPLMPOG_01846 547043.BIFPSEUDO_02454 2.44e-147 416.0 COG0009@1|root,COG0009@2|Bacteria,2GK2X@201174|Actinobacteria,4CYVA@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the SUA5 family ywlC GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - Sua5_yciO_yrdC GGPLMPOG_01847 547043.BIFPSEUDO_02453 1.04e-252 696.0 COG0472@1|root,COG0472@2|Bacteria,2GIT7@201174|Actinobacteria,4CZ4P@85004|Bifidobacteriales 201174|Actinobacteria M Glycosyl transferase family 4 rfe GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0034645,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576 2.7.8.33,2.7.8.35 ko:K02851 - - R08856 RC00002 ko00000,ko01000,ko01003,ko01005 - - - Glycos_transf_4 GGPLMPOG_01848 547043.BIFPSEUDO_02452 0.0 992.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,2GITZ@201174|Actinobacteria,4CZ2S@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth guaB GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006183,GO:0006195,GO:0006204,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009125,GO:0009126,GO:0009127,GO:0009128,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009154,GO:0009156,GO:0009158,GO:0009161,GO:0009163,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009169,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009261,GO:0009987,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046037,GO:0046039,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:0097292,GO:0097293,GO:1901068,GO:1901070,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - CBS,IMPDH GGPLMPOG_01849 547043.BIFPSEUDO_02451 3.86e-156 437.0 COG1949@1|root,COG1949@2|Bacteria,2GJR7@201174|Actinobacteria,4CYZY@85004|Bifidobacteriales 201174|Actinobacteria L 3'-to-5' exoribonuclease specific for small oligoribonucleotides orn GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360 - ko:K13288 ko03008,map03008 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - RNase_T GGPLMPOG_01850 547043.BIFPSEUDO_02450 5.9e-207 573.0 COG0561@1|root,COG0561@2|Bacteria,2HZBZ@201174|Actinobacteria,4CZNM@85004|Bifidobacteriales 201174|Actinobacteria S Sucrose-6F-phosphate phosphohydrolase - - - - - - - - - - - - Hydrolase_3 GGPLMPOG_01851 547043.BIFPSEUDO_02449 0.0 923.0 COG0507@1|root,COG0507@2|Bacteria,2HFY1@201174|Actinobacteria,4CZ0C@85004|Bifidobacteriales 201174|Actinobacteria L PIF1-like helicase - - - - - - - - - - - - PIF1 GGPLMPOG_01852 547043.BIFPSEUDO_02448 0.0 1224.0 COG0442@1|root,COG0442@2|Bacteria,2GJ9G@201174|Actinobacteria,4CZ6E@85004|Bifidobacteriales 201174|Actinobacteria J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS proS GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA_edit GGPLMPOG_01853 547043.BIFPSEUDO_02446 2.54e-128 364.0 COG0629@1|root,COG0629@2|Bacteria,2GQIQ@201174|Actinobacteria,4D17E@85004|Bifidobacteriales 201174|Actinobacteria L Single-strand binding protein family ssb2 - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB GGPLMPOG_01854 547043.BIFPSEUDO_02445 0.0 1402.0 COG3590@1|root,COG3590@2|Bacteria,2GNJY@201174|Actinobacteria,4CYVU@85004|Bifidobacteriales 201174|Actinobacteria O Peptidase family M13 pepO - 3.4.24.11,3.4.24.71 ko:K01389,ko:K01415,ko:K07386 ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010 - - - ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 - - - Peptidase_M13,Peptidase_M13_N GGPLMPOG_01855 547043.BIFPSEUDO_02444 5.71e-193 534.0 COG0024@1|root,COG0024@2|Bacteria,2GKKB@201174|Actinobacteria,4CZAA@85004|Bifidobacteriales 201174|Actinobacteria E Methionine aminopeptidase map - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 GGPLMPOG_01856 547043.BIFPSEUDO_02442 9.67e-317 862.0 COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria,4CZ2J@85004|Bifidobacteriales 201174|Actinobacteria C Citrate synthase, C-terminal domain gltA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt GGPLMPOG_01857 547043.BIFPSEUDO_02441 9.11e-216 598.0 COG2171@1|root,COG2171@2|Bacteria,2GIZ9@201174|Actinobacteria,4CYVT@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA dapD GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008666,GO:0016020,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0030312,GO:0031402,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0048037,GO:0050662,GO:0071944 2.3.1.117 ko:K00674 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv1201c Hexapep_2,THDPS_M GGPLMPOG_01858 547043.BIFPSEUDO_02440 2.04e-105 305.0 COG1576@1|root,COG1576@2|Bacteria,2IJE0@201174|Actinobacteria,4D0P5@85004|Bifidobacteriales 201174|Actinobacteria J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA rlmH - 2.1.1.177 ko:K00783 - - - - ko00000,ko01000,ko03009 - - - SPOUT_MTase GGPLMPOG_01859 547043.BIFPSEUDO_02438 2.95e-263 722.0 COG1186@1|root,COG1186@2|Bacteria,2GJ0F@201174|Actinobacteria,4CZJX@85004|Bifidobacteriales 201174|Actinobacteria J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA prfB - - ko:K02836 - - - - ko00000,ko03012 - - - PCRF,RF-1 GGPLMPOG_01860 547043.BIFPSEUDO_02437 4.32e-241 671.0 COG2884@1|root,COG2884@2|Bacteria,2GJE1@201174|Actinobacteria,4CYYQ@85004|Bifidobacteriales 201174|Actinobacteria D Cell division ATP-binding protein FtsE ftsE GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K09812 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - ABC_tran GGPLMPOG_01861 547043.BIFPSEUDO_02436 7.75e-206 571.0 COG2177@1|root,COG2177@2|Bacteria,2GJMA@201174|Actinobacteria,4CZSQ@85004|Bifidobacteriales 201174|Actinobacteria D Part of the ABC transporter FtsEX involved in cellular division ftsX GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944 - ko:K09811 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - FtsX GGPLMPOG_01862 547043.BIFPSEUDO_02435 9.94e-229 642.0 COG3942@1|root,COG3942@2|Bacteria,2GZG8@201174|Actinobacteria,4CYQJ@85004|Bifidobacteriales 201174|Actinobacteria D CHAP domain protein - - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - CHAP GGPLMPOG_01863 547043.BIFPSEUDO_04256 0.0 869.0 COG1653@1|root,COG1653@2|Bacteria,2GJIP@201174|Actinobacteria,4CZU2@85004|Bifidobacteriales 201174|Actinobacteria G Bacterial extracellular solute-binding protein - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_1,SBP_bac_8 GGPLMPOG_01864 547043.BIFPSEUDO_04255 8.54e-164 459.0 COG0311@1|root,COG0311@2|Bacteria,2GNYG@201174|Actinobacteria,4CYUS@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS pdxT GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 ko:K08681 ko00750,map00750 - R07456 RC00010,RC01783,RC03043 ko00000,ko00001,ko01000 - - - SNO GGPLMPOG_01865 547043.BIFPSEUDO_04254 6.62e-199 552.0 COG0214@1|root,COG0214@2|Bacteria,2GK1T@201174|Actinobacteria,4CZ5P@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively pdxS GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.3.3.6 ko:K06215 ko00750,map00750 - R07456 RC00010,RC01783,RC03043 ko00000,ko00001,ko01000 - - - SOR_SNZ GGPLMPOG_01866 547043.BIFPSEUDO_04251 0.0 2366.0 COG1132@1|root,COG4988@1|root,COG1132@2|Bacteria,COG4988@2|Bacteria,2GITR@201174|Actinobacteria,4CYSB@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter transmembrane region - - - ko:K06147,ko:K06148,ko:K16013 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.129,3.A.1.21 - - ABC_membrane,ABC_tran GGPLMPOG_01867 547043.BIFPSEUDO_04249 0.0 1199.0 COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4CZZP@85004|Bifidobacteriales 201174|Actinobacteria I AMP-binding enzyme fadD - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding GGPLMPOG_01868 547043.BIFPSEUDO_04248 0.0 1025.0 COG2160@1|root,COG2160@2|Bacteria,2GJNB@201174|Actinobacteria,4CZH6@85004|Bifidobacteriales 201174|Actinobacteria G Catalyzes the conversion of L-arabinose to L-ribulose araA - 5.3.1.4 ko:K01804 ko00040,ko01100,map00040,map01100 - R01761 RC00516 ko00000,ko00001,ko01000 - - - Arabinose_Iso_C,Arabinose_Isome GGPLMPOG_01869 547043.BIFPSEUDO_04247 1.1e-167 468.0 COG0235@1|root,COG0235@2|Bacteria,2GNI6@201174|Actinobacteria,4CZXX@85004|Bifidobacteriales 201174|Actinobacteria G Class II Aldolase and Adducin N-terminal domain araD - 5.1.3.4 ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 M00550 R05850 RC01479 ko00000,ko00001,ko00002,ko01000 - - - Aldolase_II GGPLMPOG_01870 547043.BIFPSEUDO_04246 0.0 1091.0 COG1070@1|root,COG1070@2|Bacteria,2GVSJ@201174|Actinobacteria,4CZK7@85004|Bifidobacteriales 201174|Actinobacteria G FGGY family of carbohydrate kinases, C-terminal domain araB - - - - - - - - - - - FGGY_C,FGGY_N GGPLMPOG_01871 547043.BIFPSEUDO_04244 2.45e-269 737.0 COG1609@1|root,COG1609@2|Bacteria,2GK1X@201174|Actinobacteria,4CYR6@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn _helix lactose operon repressor - - - - - - - - - - - - LacI,Peripla_BP_3 GGPLMPOG_01872 547043.BIFPSEUDO_04243 0.0 975.0 COG0424@1|root,COG1051@1|root,COG0424@2|Bacteria,COG1051@2|Bacteria,2GNI0@201174|Actinobacteria,4CZXF@85004|Bifidobacteriales 201174|Actinobacteria DF Maf-like protein maf GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - ko:K06287 - - - - ko00000 - - - Maf,NUDIX GGPLMPOG_01873 547043.BIFPSEUDO_04242 5.52e-240 659.0 COG0083@1|root,COG0083@2|Bacteria,2GKIW@201174|Actinobacteria,4CZN0@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate thrB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N GGPLMPOG_01874 566552.BIFCAT_00187 2.79e-306 837.0 COG0460@1|root,COG0460@2|Bacteria,2GIX9@201174|Actinobacteria,4CZVD@85004|Bifidobacteriales 201174|Actinobacteria E Homoserine dehydrogenase hom GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 1.1.1.3,2.7.2.4 ko:K00003,ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00017,M00018,M00526,M00527 R00480,R01773,R01775 RC00002,RC00043,RC00087 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv1294 ACT,Homoserine_dh,NAD_binding_3 GGPLMPOG_01875 547043.BIFPSEUDO_04240 0.0 1031.0 COG0019@1|root,COG0019@2|Bacteria,2GKAI@201174|Actinobacteria,4CYRG@85004|Bifidobacteriales 201174|Actinobacteria E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine lysA - 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC GGPLMPOG_01876 547043.BIFPSEUDO_04239 0.0 1181.0 COG0018@1|root,COG0018@2|Bacteria,2GKQ3@201174|Actinobacteria,4CZ9J@85004|Bifidobacteriales 201174|Actinobacteria J Arginyl-tRNA synthetase argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d GGPLMPOG_01877 547043.BIFPSEUDO_04238 0.0 937.0 COG0833@1|root,COG0833@2|Bacteria,2I2DX@201174|Actinobacteria,4D2V7@85004|Bifidobacteriales 201174|Actinobacteria E amino acid - - - ko:K16235 - - - - ko00000,ko02000 2.A.3.1.10 - - AA_permease GGPLMPOG_01878 547043.BIFPSEUDO_04236 1.62e-83 247.0 COG0251@1|root,COG0251@2|Bacteria,2IFCR@201174|Actinobacteria,4D0QD@85004|Bifidobacteriales 201174|Actinobacteria J Endoribonuclease L-PSP psp1 - 3.5.99.10 ko:K09022 - - R11098,R11099 RC03275,RC03354 ko00000,ko01000 - - - Ribonuc_L-PSP GGPLMPOG_01880 547043.BIFPSEUDO_04234 1.41e-156 438.0 COG2954@1|root,COG2954@2|Bacteria,2GWD8@201174|Actinobacteria,4CZKD@85004|Bifidobacteriales 201174|Actinobacteria S CYTH - - - - - - - - - - - - - GGPLMPOG_01881 547043.BIFPSEUDO_04233 8.79e-215 595.0 COG3118@1|root,COG3118@2|Bacteria,2GJ7B@201174|Actinobacteria,4CZHU@85004|Bifidobacteriales 201174|Actinobacteria O Tetratricopeptide repeat ybbN GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - ko:K05838 - - - - ko00000,ko03110 - - - TPR_19,TPR_20,Thioredoxin GGPLMPOG_01882 547043.BIFPSEUDO_04232 1.98e-232 640.0 28PR0@1|root,2ZCCY@2|Bacteria,2GNNZ@201174|Actinobacteria,4CYX7@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01883 547043.BIFPSEUDO_04231 2.16e-266 733.0 2DMQ0@1|root,32SYI@2|Bacteria,2IA0N@201174|Actinobacteria,4CYQ0@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01884 547043.BIFPSEUDO_04230 2.27e-192 536.0 COG0545@1|root,COG0545@2|Bacteria,2GJK2@201174|Actinobacteria,4CZEF@85004|Bifidobacteriales 201174|Actinobacteria M FKBP-type peptidyl-prolyl cis-trans isomerase - - 5.2.1.8 ko:K01802 - - - - ko00000,ko01000 - - - FKBP_C GGPLMPOG_01885 78346.BRUM_1412 1.08e-155 438.0 COG1637@1|root,COG1637@2|Bacteria,2GIYB@201174|Actinobacteria,4CYXA@85004|Bifidobacteriales 201174|Actinobacteria L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures nucS - - ko:K07503 - - - - ko00000,ko01000 - - - NucS GGPLMPOG_01886 547043.BIFPSEUDO_04227 2.73e-60 185.0 COG0355@1|root,COG0355@2|Bacteria,2HZPJ@201174|Actinobacteria,4D16F@85004|Bifidobacteriales 201174|Actinobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane atpC - - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_DE_N GGPLMPOG_01887 547043.BIFPSEUDO_04226 0.0 974.0 COG0055@1|root,COG0055@2|Bacteria,2GIY6@201174|Actinobacteria,4CZGY@85004|Bifidobacteriales 201174|Actinobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_N GGPLMPOG_01888 547043.BIFPSEUDO_04225 5.5e-210 581.0 COG0224@1|root,COG0224@2|Bacteria,2GJ7Q@201174|Actinobacteria,4CYVJ@85004|Bifidobacteriales 201174|Actinobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex atpG GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt GGPLMPOG_01889 547043.BIFPSEUDO_04224 0.0 1060.0 COG0056@1|root,COG0056@2|Bacteria,2GJRJ@201174|Actinobacteria,4CZI7@85004|Bifidobacteriales 201174|Actinobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N GGPLMPOG_01890 547043.BIFPSEUDO_04223 2.31e-191 531.0 COG0712@1|root,COG0712@2|Bacteria,2GMJ5@201174|Actinobacteria,4CZ9V@85004|Bifidobacteriales 201174|Actinobacteria C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpH GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - ko:K02109,ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_B,OSCP GGPLMPOG_01891 547043.BIFPSEUDO_04222 6.4e-93 274.0 COG0711@1|root,COG0711@2|Bacteria,2GJS4@201174|Actinobacteria,4CYY5@85004|Bifidobacteriales 201174|Actinobacteria C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) atpF - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_B GGPLMPOG_01892 1435051.BMOU_0411 9.64e-42 137.0 COG0636@1|root,COG0636@2|Bacteria,2GQI6@201174|Actinobacteria,4D16J@85004|Bifidobacteriales 201174|Actinobacteria C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C GGPLMPOG_01893 547043.BIFPSEUDO_04220 6.89e-190 527.0 COG0356@1|root,COG0356@2|Bacteria,2H3PR@201174|Actinobacteria,4CYZD@85004|Bifidobacteriales 201174|Actinobacteria C it plays a direct role in the translocation of protons across the membrane atpB - - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A GGPLMPOG_01894 547043.BIFPSEUDO_04219 1.4e-263 720.0 COG1897@1|root,COG1897@2|Bacteria,2GK5E@201174|Actinobacteria,4CZRK@85004|Bifidobacteriales 201174|Actinobacteria E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine metAA - 2.3.1.46 ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 M00017 R01777 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - HTS GGPLMPOG_01896 547043.BIFPSEUDO_04216 0.0 961.0 COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,4D07S@85004|Bifidobacteriales 201174|Actinobacteria C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate frc - 2.8.3.15,2.8.3.16 ko:K07544,ko:K07749 ko00623,ko01100,ko01120,ko01220,map00623,map01100,map01120,map01220 M00418 R05588 RC00014,RC00137 ko00000,ko00001,ko00002,ko01000 - - - CoA_transf_3 GGPLMPOG_01897 547043.BIFPSEUDO_04215 9.59e-247 679.0 COG0679@1|root,COG0679@2|Bacteria,2GUU2@201174|Actinobacteria,4CYYA@85004|Bifidobacteriales 201174|Actinobacteria S Membrane transport protein - - - ko:K07088 - - - - ko00000 - - - Mem_trans GGPLMPOG_01898 547043.BIFPSEUDO_04213 0.0 1199.0 COG0028@1|root,COG0028@2|Bacteria,2GM6Y@201174|Actinobacteria,4CZWD@85004|Bifidobacteriales 201174|Actinobacteria EH Thiamine pyrophosphate enzyme, central domain oxc - 4.1.1.8 ko:K01577 ko00630,ko01100,map00630,map01100 - R01908 RC00620 ko00000,ko00001,ko01000 - - iNJ661.Rv0118c TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N GGPLMPOG_01899 547043.BIFPSEUDO_04211 4.44e-223 615.0 COG4932@1|root,COG4932@2|Bacteria,2IK2B@201174|Actinobacteria,4D2XD@85004|Bifidobacteriales 201174|Actinobacteria M LPXTG-motif cell wall anchor domain protein - - - - - - - - - - - - - GGPLMPOG_01900 547043.BIFPSEUDO_04210 0.0 1505.0 COG0366@1|root,COG0366@2|Bacteria,2GJKR@201174|Actinobacteria,4CZSK@85004|Bifidobacteriales 201174|Actinobacteria G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB glgE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.4.99.16 ko:K16147 ko00500,ko01100,map00500,map01100 - R09994 - ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,DUF3416 GGPLMPOG_01901 547043.BIFPSEUDO_04209 2.28e-118 338.0 COG0221@1|root,COG0221@2|Bacteria,2GM7F@201174|Actinobacteria,4CYWS@85004|Bifidobacteriales 201174|Actinobacteria C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions ppa GO:0000287,GO:0003674,GO:0003824,GO:0004427,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0071944 3.6.1.1 ko:K01507 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - iNJ661.Rv3628 Pyrophosphatase GGPLMPOG_01902 547043.BIFPSEUDO_04208 7.04e-127 361.0 COG1971@1|root,COG1971@2|Bacteria,2GNBU@201174|Actinobacteria,4D01X@85004|Bifidobacteriales 201174|Actinobacteria P Probably functions as a manganese efflux pump mntP - - - - - - - - - - - Mntp GGPLMPOG_01903 547043.BIFPSEUDO_04207 1.09e-173 485.0 2A0I6@1|root,30NNB@2|Bacteria,2GJ8M@201174|Actinobacteria,4D0ZN@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01904 547043.BIFPSEUDO_04206 1.1e-172 482.0 COG0745@1|root,COG0745@2|Bacteria,2GJGU@201174|Actinobacteria,4CZB9@85004|Bifidobacteriales 201174|Actinobacteria KT Transcriptional regulatory protein, C terminal glnR - - - - - - - - - - - Trans_reg_C GGPLMPOG_01905 547043.BIFPSEUDO_04205 1.59e-156 438.0 COG0177@1|root,COG0177@2|Bacteria,2GJ01@201174|Actinobacteria,4CZ31@85004|Bifidobacteriales 201174|Actinobacteria L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate nth GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD GGPLMPOG_01906 547043.BIFPSEUDO_04204 0.0 1006.0 COG0747@1|root,COG0747@2|Bacteria,2GM5G@201174|Actinobacteria,4CYUZ@85004|Bifidobacteriales 201174|Actinobacteria E Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 GGPLMPOG_01907 547043.BIFPSEUDO_04203 0.0 1867.0 COG0525@1|root,COG0525@2|Bacteria,2GK8H@201174|Actinobacteria,4CYVG@85004|Bifidobacteriales 201174|Actinobacteria J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS - 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1 GGPLMPOG_01908 547043.BIFPSEUDO_04201 0.0 1234.0 COG1511@1|root,COG1511@2|Bacteria,2I9PN@201174|Actinobacteria,4CZC2@85004|Bifidobacteriales 201174|Actinobacteria S domain protein - - - - - - - - - - - - - GGPLMPOG_01909 547043.BIFPSEUDO_04200 2.33e-89 262.0 COG1605@1|root,COG1605@2|Bacteria,2IQ46@201174|Actinobacteria,4D12A@85004|Bifidobacteriales 201174|Actinobacteria E Chorismate mutase type II tyrA - 5.4.99.5 ko:K04092 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R01715 RC03116 ko00000,ko00001,ko00002,ko01000 - - - CM_2 GGPLMPOG_01910 547043.BIFPSEUDO_04199 1.09e-104 303.0 COG1522@1|root,COG1522@2|Bacteria,2GK3G@201174|Actinobacteria,4D0XT@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn_helix ASNC type lrp_3 - - ko:K03719 - - - - ko00000,ko03000,ko03036 - - - AsnC_trans_reg,HTH_24,HTH_AsnC-type GGPLMPOG_01911 547043.BIFPSEUDO_04198 0.0 1060.0 COG1158@1|root,COG1158@2|Bacteria,2GIWY@201174|Actinobacteria,4CZ2Z@85004|Bifidobacteriales 201174|Actinobacteria K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template rho GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006360,GO:0006363,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - ko:K03628 ko03018,map03018 - - - ko00000,ko00001,ko03019,ko03021 - - - ATP-synt_ab,Rho_N,Rho_RNA_bind GGPLMPOG_01912 547043.BIFPSEUDO_04196 0.0 1097.0 COG1232@1|root,COG1232@2|Bacteria,2HZ9K@201174|Actinobacteria,4CZ3Z@85004|Bifidobacteriales 201174|Actinobacteria H Flavin containing amine oxidoreductase - - - - - - - - - - - - Amino_oxidase,NAD_binding_8 GGPLMPOG_01913 547043.BIFPSEUDO_04195 1.43e-67 204.0 2AFXT@1|root,3161G@2|Bacteria,2IKPZ@201174|Actinobacteria,4D0UV@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF2469) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - DUF2469 GGPLMPOG_01914 547043.BIFPSEUDO_04193 1.4e-261 717.0 COG1670@1|root,COG1670@2|Bacteria,2I2GV@201174|Actinobacteria,4CYPW@85004|Bifidobacteriales 201174|Actinobacteria J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3 GGPLMPOG_01915 547043.BIFPSEUDO_04192 0.0 982.0 COG0064@1|root,COG0064@2|Bacteria,2GJJH@201174|Actinobacteria,4CYUY@85004|Bifidobacteriales 201174|Actinobacteria J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatB GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - GatB_N,GatB_Yqey GGPLMPOG_01916 547043.BIFPSEUDO_04191 0.0 991.0 COG0154@1|root,COG0154@2|Bacteria,2GJK5@201174|Actinobacteria,4CZ1X@85004|Bifidobacteriales 201174|Actinobacteria F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gatA GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase GGPLMPOG_01917 547043.BIFPSEUDO_04190 1.35e-62 192.0 COG0721@1|root,COG0721@2|Bacteria,2IQJN@201174|Actinobacteria,4D10U@85004|Bifidobacteriales 201174|Actinobacteria J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatC GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Glu-tRNAGln GGPLMPOG_01918 401473.BDP_1991 1.46e-167 475.0 COG5340@1|root,COG5340@2|Bacteria,2ICPH@201174|Actinobacteria,4CZJ7@85004|Bifidobacteriales 201174|Actinobacteria K Psort location Cytoplasmic, score - - - - - - - - - - - - - GGPLMPOG_01919 1680.BADO_1554 2.55e-168 476.0 COG0566@1|root,COG0566@2|Bacteria,2GM1A@201174|Actinobacteria,4CZE8@85004|Bifidobacteriales 201174|Actinobacteria J RNA methyltransferase TrmH family trmH - 2.1.1.34 ko:K00556 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase GGPLMPOG_01920 566552.BIFCAT_00272 4.93e-134 382.0 COG0461@1|root,COG0461@2|Bacteria,2HZDS@201174|Actinobacteria,4CZZ6@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) pyrE1 - - - - - - - - - - - - GGPLMPOG_01921 547043.BIFPSEUDO_04183 9.34e-260 719.0 COG1322@1|root,COG1322@2|Bacteria,2GP4U@201174|Actinobacteria,4CZA5@85004|Bifidobacteriales 201174|Actinobacteria S RmuC family rmuC - - ko:K09760 - - - - ko00000 - - - RmuC GGPLMPOG_01922 547043.BIFPSEUDO_04181 1.3e-186 521.0 COG2217@1|root,COG2217@2|Bacteria,2GM0U@201174|Actinobacteria,4CZ7S@85004|Bifidobacteriales 201174|Actinobacteria P Heavy metal translocating P-type atpase - - 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - - GGPLMPOG_01923 547043.BIFPSEUDO_04180 0.0 1709.0 COG0542@1|root,COG0542@2|Bacteria,2GJ73@201174|Actinobacteria,4CZDY@85004|Bifidobacteriales 201174|Actinobacteria O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB - - ko:K03695,ko:K03696 ko01100,ko04213,map01100,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N GGPLMPOG_01924 547043.BIFPSEUDO_04179 1.36e-209 578.0 COG0179@1|root,COG0179@2|Bacteria,2GN2G@201174|Actinobacteria,4CZH5@85004|Bifidobacteriales 201174|Actinobacteria Q Fumarylacetoacetate (FAA) hydrolase family - - - - - - - - - - - - DUF2437,FAA_hydrolase GGPLMPOG_01925 547043.BIFPSEUDO_04178 1.38e-187 522.0 COG0325@1|root,COG0325@2|Bacteria,2GMRJ@201174|Actinobacteria,4CZUY@85004|Bifidobacteriales 201174|Actinobacteria S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis - - - ko:K06997 - - - - ko00000 - - - Ala_racemase_N GGPLMPOG_01926 547043.BIFPSEUDO_04177 2.82e-105 304.0 2AWBM@1|root,31N7D@2|Bacteria,2IP6P@201174|Actinobacteria,4D14B@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01927 547043.BIFPSEUDO_04176 1.82e-266 729.0 COG0008@1|root,COG0008@2|Bacteria,2GKMT@201174|Actinobacteria,4CYRY@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the class-I aminoacyl-tRNA synthetase family gluQ - 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - - tRNA-synt_1c GGPLMPOG_01928 547043.BIFPSEUDO_04175 2.6e-65 201.0 COG5479@1|root,COG5479@2|Bacteria,2GMJR@201174|Actinobacteria,4D0RU@85004|Bifidobacteriales 201174|Actinobacteria M Protein of unknown function (DUF3152) - - - - - - - - - - - - DUF3152 GGPLMPOG_01930 547043.BIFPSEUDO_04172 1.1e-177 494.0 COG0580@1|root,COG0580@2|Bacteria,2GKK3@201174|Actinobacteria,4CZ7F@85004|Bifidobacteriales 201174|Actinobacteria U Belongs to the MIP aquaporin (TC 1.A.8) family glpF - - ko:K02440 - - - - ko00000,ko02000 1.A.8.1,1.A.8.2 - - MIP GGPLMPOG_01932 547043.BIFPSEUDO_04166 1.16e-92 271.0 COG0359@1|root,COG0359@2|Bacteria,2IKX7@201174|Actinobacteria,4D0P9@85004|Bifidobacteriales 201174|Actinobacteria J Binds to the 23S rRNA rplI GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02939 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L9_C,Ribosomal_L9_N GGPLMPOG_01933 547043.BIFPSEUDO_04165 3.05e-48 154.0 COG0238@1|root,COG0238@2|Bacteria,2IQ92@201174|Actinobacteria,4D103@85004|Bifidobacteriales 201174|Actinobacteria J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit rpsR GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02963 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S18 GGPLMPOG_01934 547043.BIFPSEUDO_04164 5.64e-107 313.0 COG0629@1|root,COG0629@2|Bacteria,2GMM3@201174|Actinobacteria,4CZ5V@85004|Bifidobacteriales 201174|Actinobacteria L Single-stranded DNA-binding protein ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB GGPLMPOG_01935 1680.BADO_1535 7.12e-62 189.0 COG0360@1|root,COG0360@2|Bacteria,2IQHD@201174|Actinobacteria,4D10X@85004|Bifidobacteriales 201174|Actinobacteria J Binds together with S18 to 16S ribosomal RNA rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0019843,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071944,GO:0097159,GO:1901363,GO:1990904 - ko:K02990 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S6 GGPLMPOG_01936 547043.BIFPSEUDO_04162 8.85e-243 667.0 COG0462@1|root,COG0462@2|Bacteria,2GJ9S@201174|Actinobacteria,4CZPM@85004|Bifidobacteriales 201174|Actinobacteria F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006015,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046390,GO:0046391,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901576 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran_N GGPLMPOG_01941 547043.BIFPSEUDO_03310 5.49e-93 271.0 29XRD@1|root,30JH2@2|Bacteria,2IT75@201174|Actinobacteria,4D1B3@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01942 547043.BIFPSEUDO_03309 4.77e-38 127.0 COG1476@1|root,COG1476@2|Bacteria,2HZSM@201174|Actinobacteria,4D1JS@85004|Bifidobacteriales 201174|Actinobacteria K Cro/C1-type HTH DNA-binding domain - - - - - - - - - - - - HTH_3 GGPLMPOG_01943 547043.BIFPSEUDO_03308 4.61e-95 279.0 2BIKN@1|root,32CTH@2|Bacteria,2IQ4U@201174|Actinobacteria,4D19Y@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01944 547043.BIFPSEUDO_03307 3.16e-125 357.0 COG0394@1|root,COG0394@2|Bacteria,2GMPR@201174|Actinobacteria,4D0GD@85004|Bifidobacteriales 201174|Actinobacteria T Low molecular weight phosphatase family etp - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - LMWPc GGPLMPOG_01945 547043.BIFPSEUDO_03306 0.0 895.0 COG0489@1|root,COG3944@1|root,COG0489@2|Bacteria,COG3944@2|Bacteria,2GJ1Y@201174|Actinobacteria,4CZKW@85004|Bifidobacteriales 201174|Actinobacteria DM Psort location CytoplasmicMembrane, score wcoI - - - - - - - - - - - AAA_31,CbiA,GNVR,ParA,Wzz GGPLMPOG_01946 547043.BIFPSEUDO_03305 0.0 1864.0 COG1501@1|root,COG1501@2|Bacteria,2GP4V@201174|Actinobacteria,4D005@85004|Bifidobacteriales 201174|Actinobacteria G Belongs to the glycosyl hydrolase 31 family - - - - - - - - - - - - DUF5110,Glyco_hydro_31 GGPLMPOG_01947 547043.BIFPSEUDO_03304 5.43e-189 525.0 COG0395@1|root,COG0395@2|Bacteria,2GK1V@201174|Actinobacteria,4CZVI@85004|Bifidobacteriales 201174|Actinobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02026,ko:K10190 ko02010,map02010 M00199,M00207 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.4 - - BPD_transp_1 GGPLMPOG_01948 547043.BIFPSEUDO_03303 2.74e-209 578.0 COG1175@1|root,COG1175@2|Bacteria,2GKJI@201174|Actinobacteria,4D0GQ@85004|Bifidobacteriales 201174|Actinobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02025 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 GGPLMPOG_01949 547043.BIFPSEUDO_03302 0.0 932.0 COG1653@1|root,COG1653@2|Bacteria,2HZBJ@201174|Actinobacteria,4CZJJ@85004|Bifidobacteriales 201174|Actinobacteria G Bacterial extracellular solute-binding protein - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_1,SBP_bac_8 GGPLMPOG_01950 547043.BIFPSEUDO_03301 8.42e-237 652.0 COG1609@1|root,COG1609@2|Bacteria,2GJBJ@201174|Actinobacteria,4CZ1Y@85004|Bifidobacteriales 201174|Actinobacteria K Psort location Cytoplasmic, score - - - - - - - - - - - - LacI,Peripla_BP_3 GGPLMPOG_01951 547043.BIFPSEUDO_03298 6.38e-233 641.0 COG1609@1|root,COG1609@2|Bacteria,2GJDS@201174|Actinobacteria,4D0SN@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn _helix lactose operon repressor - - - - - - - - - - - - LacI,Peripla_BP_3 GGPLMPOG_01952 547043.BIFPSEUDO_03297 5.09e-283 773.0 COG1653@1|root,COG1653@2|Bacteria,2I3BP@201174|Actinobacteria,4CZDQ@85004|Bifidobacteriales 201174|Actinobacteria G Bacterial extracellular solute-binding protein - - - ko:K02027,ko:K10117 ko02010,map02010 M00196,M00207 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.28 - - SBP_bac_8 GGPLMPOG_01953 547043.BIFPSEUDO_03296 4.31e-207 573.0 COG1175@1|root,COG1175@2|Bacteria,2GJGB@201174|Actinobacteria,4D084@85004|Bifidobacteriales 201174|Actinobacteria G PFAM binding-protein-dependent transport systems inner membrane component - - - ko:K02025 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 GGPLMPOG_01954 547043.BIFPSEUDO_03295 1.49e-185 516.0 COG0395@1|root,COG0395@2|Bacteria,2GNGG@201174|Actinobacteria,4CZP2@85004|Bifidobacteriales 201174|Actinobacteria G Binding-protein-dependent transport system inner membrane component - - - ko:K02026 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 GGPLMPOG_01955 547043.BIFPSEUDO_03294 0.0 1439.0 COG1501@1|root,COG1501@2|Bacteria,2GP4V@201174|Actinobacteria,4D005@85004|Bifidobacteriales 201174|Actinobacteria G Belongs to the glycosyl hydrolase 31 family - - 3.2.1.177 ko:K01811 - - - - ko00000,ko01000 - GH31 - Gal_mutarotas_2,Glyco_hydro_31 GGPLMPOG_01956 547043.BIFPSEUDO_03292 1.61e-73 223.0 COG3304@1|root,COG3304@2|Bacteria,2IKS5@201174|Actinobacteria,4D11K@85004|Bifidobacteriales 201174|Actinobacteria S Inner membrane component domain yccF - - - - - - - - - - - YccF GGPLMPOG_01957 566552.BIFCAT_01244 1.49e-133 379.0 2B5KQ@1|root,31YFR@2|Bacteria,2HZXM@201174|Actinobacteria,4D25N@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01958 1680.BADO_1363 2.84e-51 171.0 COG3274@1|root,COG3274@2|Bacteria,2GITX@201174|Actinobacteria,4D0JX@85004|Bifidobacteriales 201174|Actinobacteria S enterobacterial common antigen metabolic process - - - - - - - - - - - - Acyl_transf_3 GGPLMPOG_01959 566552.BIFCAT_01245 2.98e-147 423.0 COG3274@1|root,COG3274@2|Bacteria,2GITX@201174|Actinobacteria,4D0JX@85004|Bifidobacteriales 201174|Actinobacteria S enterobacterial common antigen metabolic process - - - - - - - - - - - - Acyl_transf_3 GGPLMPOG_01960 1680.BADO_1646 1.79e-254 708.0 COG1035@1|root,COG1035@2|Bacteria,2GM7P@201174|Actinobacteria,4D0N5@85004|Bifidobacteriales 201174|Actinobacteria C Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term - - 1.12.98.1 ko:K00441 ko00680,ko01100,ko01120,map00680,map01100,map01120 - R03025 RC02628 ko00000,ko00001,ko01000 - - - FrhB_FdhB_C,FrhB_FdhB_N GGPLMPOG_01961 1437610.BREU_0821 1.03e-103 314.0 COG0778@1|root,COG0778@2|Bacteria,2IE9H@201174|Actinobacteria,4CZI3@85004|Bifidobacteriales 201174|Actinobacteria C Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - Nitroreductase GGPLMPOG_01962 509191.AEDB02000099_gene3986 9.62e-144 428.0 COG2244@1|root,COG2244@2|Bacteria,1TR1W@1239|Firmicutes,24917@186801|Clostridia,3WJMN@541000|Ruminococcaceae 186801|Clostridia S Psort location CytoplasmicMembrane, score - - - - - - - - - - - - Polysacc_synt_C GGPLMPOG_01963 158189.SpiBuddy_0394 4.13e-59 199.0 COG1216@1|root,COG1216@2|Bacteria 2|Bacteria V Glycosyl transferase, family 2 - - 2.4.1.293 ko:K17250 - - - - ko00000,ko01000,ko01003 - GT2 - Glycos_transf_2 GGPLMPOG_01964 384765.SIAM614_08028 0.000173 52.4 COG3307@1|root,COG3307@2|Bacteria,1R5EX@1224|Proteobacteria,2TTQF@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Lipid A core - O-antigen ligase and related enzymes - - - - - - - - - - - - Wzy_C GGPLMPOG_01965 293826.Amet_0211 2.97e-79 254.0 COG2327@1|root,COG2327@2|Bacteria,1V4VX@1239|Firmicutes,24C2N@186801|Clostridia,36HW6@31979|Clostridiaceae 186801|Clostridia M Polysaccharide pyruvyl transferase - - - - - - - - - - - - PS_pyruv_trans GGPLMPOG_01966 762968.HMPREF9441_01639 9.67e-39 147.0 COG1216@1|root,COG1216@2|Bacteria,4NU3S@976|Bacteroidetes,2G2Z8@200643|Bacteroidia 976|Bacteroidetes S group 2 family protein - - - - - - - - - - - - Glycos_transf_2 GGPLMPOG_01967 1693.BMIN_0958 7.65e-163 464.0 COG3774@1|root,COG3774@2|Bacteria,2ICTC@201174|Actinobacteria,4D0R2@85004|Bifidobacteriales 201174|Actinobacteria M Capsular polysaccharide synthesis protein - - - - - - - - - - - - Caps_synth GGPLMPOG_01968 547043.BIFPSEUDO_03265 2.81e-256 711.0 COG0438@1|root,COG0438@2|Bacteria,2GM53@201174|Actinobacteria,4D0F1@85004|Bifidobacteriales 201174|Actinobacteria M Glycosyl transferase 4-like domain - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 GGPLMPOG_01969 547043.BIFPSEUDO_03264 1.28e-274 751.0 COG0438@1|root,COG0438@2|Bacteria,2IBM0@201174|Actinobacteria,4CZE4@85004|Bifidobacteriales 201174|Actinobacteria M Domain of unknown function (DUF1972) - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 GGPLMPOG_01970 547043.BIFPSEUDO_03262 1.61e-258 709.0 COG0438@1|root,COG0438@2|Bacteria,2GNR8@201174|Actinobacteria,4D0M2@85004|Bifidobacteriales 201174|Actinobacteria M Psort location Cytoplasmic, score 8.87 - - - ko:K19424 - - - - ko00000,ko01000,ko01003 - GT4 - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 GGPLMPOG_01971 547043.BIFPSEUDO_03261 1.8e-310 845.0 COG0438@1|root,COG0438@2|Bacteria,2HZCM@201174|Actinobacteria,4CZSE@85004|Bifidobacteriales 201174|Actinobacteria M Glycosyl transferases group 1 - - - ko:K00713 - - - - ko00000,ko01000,ko01003,ko01005 - - - Glycos_transf_1 GGPLMPOG_01972 547043.BIFPSEUDO_03260 0.0 874.0 COG2244@1|root,COG2244@2|Bacteria,2I9QU@201174|Actinobacteria,4D0AU@85004|Bifidobacteriales 201174|Actinobacteria S Polysaccharide biosynthesis protein - - - - - - - - - - - - Polysacc_synt,Polysacc_synt_C GGPLMPOG_01973 547043.BIFPSEUDO_03259 3.16e-252 691.0 COG1216@1|root,COG1216@2|Bacteria,2I2EQ@201174|Actinobacteria,4D2X1@85004|Bifidobacteriales 201174|Actinobacteria S Glycosyltransferase like family 2 - - 2.7.8.12 ko:K09809,ko:K19427 - - - - ko00000,ko01000 - GT2 - Glycos_transf_2 GGPLMPOG_01974 326426.Bbr_0446 1.37e-141 402.0 COG0110@1|root,COG0110@2|Bacteria,2IKA9@201174|Actinobacteria,4D1Y9@85004|Bifidobacteriales 201174|Actinobacteria H Hexapeptide repeat of succinyl-transferase - - - - - - - - - - - - Hexapep GGPLMPOG_01975 547043.BIFPSEUDO_03257 2.26e-267 731.0 COG2327@1|root,COG2327@2|Bacteria,2IC1G@201174|Actinobacteria,4D09D@85004|Bifidobacteriales 201174|Actinobacteria S Polysaccharide pyruvyl transferase - - - - - - - - - - - - PS_pyruv_trans GGPLMPOG_01976 547043.BIFPSEUDO_03256 1.67e-248 681.0 COG0778@1|root,COG0778@2|Bacteria,2IE9H@201174|Actinobacteria,4CZI3@85004|Bifidobacteriales 201174|Actinobacteria C Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - Nitroreductase GGPLMPOG_01978 326426.Bbr_0450 4.04e-226 626.0 2DR4Q@1|root,33A5I@2|Bacteria,2H1FR@201174|Actinobacteria,4D1P6@85004|Bifidobacteriales 201174|Actinobacteria S EpsG family - - - - - - - - - - - - EpsG GGPLMPOG_01980 547043.BIFPSEUDO_03251 9.52e-86 259.0 COG3274@1|root,COG3274@2|Bacteria,2GITX@201174|Actinobacteria,4D0JX@85004|Bifidobacteriales 201174|Actinobacteria S enterobacterial common antigen metabolic process - - - - - - - - - - - - Acyl_transf_3 GGPLMPOG_01981 547043.BIFPSEUDO_03251 8.84e-87 263.0 COG3274@1|root,COG3274@2|Bacteria,2GITX@201174|Actinobacteria,4D0JX@85004|Bifidobacteriales 201174|Actinobacteria S enterobacterial common antigen metabolic process - - - - - - - - - - - - Acyl_transf_3 GGPLMPOG_01982 1121924.ATWH01000022_gene3180 2e-40 152.0 2DR19@1|root,339RS@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - SIR2_2 GGPLMPOG_01983 33905.BTHE_1830 1.82e-64 198.0 28U4U@1|root,2ZGAR@2|Bacteria,2GZX6@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01984 33905.BTHE_1831 8.14e-72 219.0 2DQVX@1|root,338ZP@2|Bacteria,2GSYV@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01986 158787.BSCA_2306 2.23e-135 395.0 COG1609@1|root,COG1609@2|Bacteria,2GJDS@201174|Actinobacteria,4D0SN@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn _helix lactose operon repressor - - - - - - - - - - - - LacI,Peripla_BP_3 GGPLMPOG_01987 158787.BSCA_2307 0.0 1093.0 COG1501@1|root,COG1501@2|Bacteria,2GP4V@201174|Actinobacteria,4D005@85004|Bifidobacteriales 201174|Actinobacteria G Belongs to the glycosyl hydrolase 31 family - - 3.2.1.177 ko:K01811 - - - - ko00000,ko01000 - GH31 - Gal_mutarotas_2,Glyco_hydro_31 GGPLMPOG_01988 1437600.JDUI01000012_gene1189 2.84e-147 420.0 COG1175@1|root,COG1175@2|Bacteria,2I330@201174|Actinobacteria,4CZJC@85004|Bifidobacteriales 201174|Actinobacteria G Binding-protein-dependent transport system inner membrane component msmF - - ko:K10118 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - BPD_transp_1 GGPLMPOG_01989 518635.BIFANG_02287 1.82e-161 456.0 COG0395@1|root,COG0395@2|Bacteria,2GJNN@201174|Actinobacteria,4CYZ9@85004|Bifidobacteriales 201174|Actinobacteria G ABC transporter permease - - - ko:K02026,ko:K10119 ko02010,map02010 M00196,M00207 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.28 - - BPD_transp_1 GGPLMPOG_01990 158787.BSCA_2308 3.56e-239 667.0 COG1653@1|root,COG1653@2|Bacteria,2GWCY@201174|Actinobacteria,4CYWG@85004|Bifidobacteriales 201174|Actinobacteria G Bacterial extracellular solute-binding protein amyE - - ko:K10117 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - SBP_bac_8 GGPLMPOG_01991 547043.BIFPSEUDO_03248 4.52e-264 729.0 2AZ7Y@1|root,31REU@2|Bacteria,2GPBK@201174|Actinobacteria,4D1AQ@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01992 547043.BIFPSEUDO_03247 0.0 1079.0 COG2148@1|root,COG2148@2|Bacteria,2GK0M@201174|Actinobacteria,4CZ4J@85004|Bifidobacteriales 201174|Actinobacteria M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - - - - - - - - - - Bac_transf,CoA_binding_3 GGPLMPOG_01993 547043.BIFPSEUDO_03246 0.0 1202.0 COG2959@1|root,COG2959@2|Bacteria,2I2HI@201174|Actinobacteria,4CYVN@85004|Bifidobacteriales 201174|Actinobacteria H Protein of unknown function (DUF4012) - - - - - - - - - - - - DUF4012 GGPLMPOG_01994 547043.BIFPSEUDO_03245 1.85e-240 661.0 COG3021@1|root,COG3021@2|Bacteria,2GKXC@201174|Actinobacteria,4CZVK@85004|Bifidobacteriales 201174|Actinobacteria S Endonuclease/Exonuclease/phosphatase family staP - - ko:K18353 ko01502,ko02020,map01502,map02020 M00651 - - ko00000,ko00001,ko00002,ko01504 - - - Exo_endo_phos GGPLMPOG_01995 547043.BIFPSEUDO_03244 2.52e-63 194.0 2AVIH@1|root,31MB1@2|Bacteria,2IMY2@201174|Actinobacteria,4D12K@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - GGPLMPOG_01996 547043.BIFPSEUDO_03243 0.0 990.0 COG0477@1|root,COG2814@2|Bacteria,2GIZX@201174|Actinobacteria,4CZWX@85004|Bifidobacteriales 201174|Actinobacteria U Drug resistance MFS transporter, drug H antiporter-2 family - - - - - - - - - - - - MFS_1 GGPLMPOG_01997 547043.BIFPSEUDO_03242 3.01e-312 850.0 COG5001@1|root,COG5001@2|Bacteria,2HZW6@201174|Actinobacteria,4D20A@85004|Bifidobacteriales 201174|Actinobacteria T Diguanylate cyclase (GGDEF) domain protein - - - - - - - - - - - - GGDEF GGPLMPOG_01998 547043.BIFPSEUDO_03241 3.49e-155 439.0 COG2356@1|root,COG2356@2|Bacteria,2GJ38@201174|Actinobacteria,4CZCY@85004|Bifidobacteriales 201174|Actinobacteria L Protein of unknown function (DUF1524) - - - - - - - - - - - - DUF1524 GGPLMPOG_01999 547043.BIFPSEUDO_03240 2.98e-212 585.0 COG0656@1|root,COG0656@2|Bacteria,2GJQ7@201174|Actinobacteria,4CYUN@85004|Bifidobacteriales 201174|Actinobacteria S Oxidoreductase, aldo keto reductase family protein - - - - - - - - - - - - Aldo_ket_red GGPLMPOG_02000 547043.BIFPSEUDO_03238 5.4e-309 843.0 COG1914@1|root,COG1914@2|Bacteria,2GJSM@201174|Actinobacteria,4CZZB@85004|Bifidobacteriales 201174|Actinobacteria P H( )-stimulated, divalent metal cation uptake system mntH GO:0000041,GO:0006810,GO:0006811,GO:0006812,GO:0006826,GO:0006828,GO:0006829,GO:0008150,GO:0030001,GO:0034220,GO:0034755,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071421,GO:0071577,GO:0071578,GO:0072511,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098739,GO:0099587 - ko:K03322 - - - - ko00000,ko02000 2.A.55.2.6,2.A.55.3 - - Nramp GGPLMPOG_02001 547043.BIFPSEUDO_03236 8.33e-254 696.0 COG1609@1|root,COG1609@2|Bacteria,2GJ5Q@201174|Actinobacteria,4D040@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn _helix lactose operon repressor - - - - - - - - - - - - LacI,Peripla_BP_3 GGPLMPOG_02002 547043.BIFPSEUDO_03235 0.0 1449.0 COG1874@1|root,COG1874@2|Bacteria,2GMDT@201174|Actinobacteria,4CZ38@85004|Bifidobacteriales 201174|Actinobacteria G Psort location Cytoplasmic, score 8.87 bga1 - 3.2.1.23 ko:K12308 ko00052,map00052 - R01105 RC00452 ko00000,ko00001,ko01000 - - - Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M ## 1796 queries scanned ## Total time (seconds): 1.5121665000915527 ## Rate: 1187.70 q/s