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Overview
1.1
1.2
1.3
3.1
12.1
17.1

### Identified secondary metabolite regions using strictness 'relaxed'

gnlProkkaHDCEGNDM_1 (original name was: gnl|Prokka|HDCEGNDM_1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | lanthipeptide-class-ii | 1 | 15,721 | streptococcin A-FF22 | RiPP:Lanthipeptide | 50%
Region 1.2 | transAT-PKS,NRPS | 16,225 | 74,622 | thermophilin 1277 | RiPP:Lanthipeptide | 10%
Region 1.3 | lanthipeptide-class-ii | 160,394 | 181,216 | salivaricin A | RiPP:Lanthipeptide | 87%

gnlProkkaHDCEGNDM_3 (original name was: gnl|Prokka|HDCEGNDM_3)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 3.1 | RiPP-like | 12,295 | 24,391 | quinolidomicin A | Polyketide | 3%

gnlProkkaHDCEGNDM_13 (original name was: gnl|Prokka|HDCEGNDM_13)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 12.1 | T3PKS | 458,893 | 500,059 | coumermycin A1 | Saccharide:Hybrid/tailoring saccharide+Other:Aminocoumarin | 6%

gnlProkkaHDCEGNDM_21 (original name was: gnl|Prokka|HDCEGNDM_21)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 17.1 | RiPP-like | 116,469 | 135,260 |

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | lanthipeptide-class-ii | 1 | 15,721 | streptococcin A-FF22 | RiPP:Lanthipeptide | 50%
Region 1.2 | transAT-PKS,NRPS | 16,225 | 74,622 | thermophilin 1277 | RiPP:Lanthipeptide | 10%
Region 1.3 | lanthipeptide-class-ii | 160,394 | 181,216 | salivaricin A | RiPP:Lanthipeptide | 87%
Region 3.1 | RiPP-like | 12,295 | 24,391 | quinolidomicin A | Polyketide | 3%
Region 12.1 | T3PKS | 458,893 | 500,059 | coumermycin A1 | Saccharide:Hybrid/tailoring saccharide+Other:Aminocoumarin | 6%
Region 17.1 | RiPP-like | 116,469 | 135,260 |

No secondary metabolite regions were found in these records:
  gnlProkkaHDCEGNDM_2 (original name was: gnl|Prokka|HDCEGNDM_2)
  gnlProkkaHDCEGNDM_5 (original name was: gnl|Prokka|HDCEGNDM_5)
  gnlProkkaHDCEGNDM_6 (original name was: gnl|Prokka|HDCEGNDM_6)
  gnlProkkaHDCEGNDM_7 (original name was: gnl|Prokka|HDCEGNDM_7)
  gnlProkkaHDCEGNDM_8 (original name was: gnl|Prokka|HDCEGNDM_8)
  gnlProkkaHDCEGNDM_9 (original name was: gnl|Prokka|HDCEGNDM_9)
  gnlProkkaHDCEGNDM_10 (original name was: gnl|Prokka|HDCEGNDM_10)
  gnlProkkaHDCEGNDM_11 (original name was: gnl|Prokka|HDCEGNDM_11)
  gnlProkkaHDCEGNDM_12 (original name was: gnl|Prokka|HDCEGNDM_12)
  gnlProkkaHDCEGNDM_15 (original name was: gnl|Prokka|HDCEGNDM_15)
  gnlProkkaHDCEGNDM_17 (original name was: gnl|Prokka|HDCEGNDM_17)
  gnlProkkaHDCEGNDM_19 (original name was: gnl|Prokka|HDCEGNDM_19)
  gnlProkkaHDCEGNDM_20 (original name was: gnl|Prokka|HDCEGNDM_20)
  gnlProkkaHDCEGNDM_22 (original name was: gnl|Prokka|HDCEGNDM_22)
  gnlProkkaHDCEGNDM_23 (original name was: gnl|Prokka|HDCEGNDM_23)
  gnlProkkaHDCEGNDM_24 (original name was: gnl|Prokka|HDCEGNDM_24)
  gnlProkkaHDCEGNDM_25 (original name was: gnl|Prokka|HDCEGNDM_25)
  gnlProkkaHDCEGNDM_26 (original name was: gnl|Prokka|HDCEGNDM_26)
  gnlProkkaHDCEGNDM_27 (original name was: gnl|Prokka|HDCEGNDM_27)
  gnlProkkaHDCEGNDM_28 (original name was: gnl|Prokka|HDCEGNDM_28)
  gnlProkkaHDCEGNDM_29 (original name was: gnl|Prokka|HDCEGNDM_29)
  gnlProkkaHDCEGNDM_30 (original name was: gnl|Prokka|HDCEGNDM_30)
  gnlProkkaHDCEGNDM_31 (original name was: gnl|Prokka|HDCEGNDM_31)
  gnlProkkaHDCEGNDM_32 (original name was: gnl|Prokka|HDCEGNDM_32)
  gnlProkkaHDCEGNDM_33 (original name was: gnl|Prokka|HDCEGNDM_33)
  gnlProkkaHDCEGNDM_34 (original name was: gnl|Prokka|HDCEGNDM_34)

Compact view
gnlProkkaHDCEGNDM_1 - Region 1 - lanthipeptide-class-ii
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1 - 15,721 nt. (total: 15,721 nt) Show pHMM detection rules used
Region on contig edge.
lanthipeptide-class-ii: cds(LANC_like and DUF4135)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
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Lanthipeptides
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
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Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Lanthipeptide predictions
Shows the possible core peptides for each biosynthetic enzyme.
Includes CompaRiPPson results for any available databases, with a detailed explanation here.

#### Lanthipeptide(s) for ctg1_5

ctg1_4
Leader:
MAKQQMNLVEIEAMNSLQELTLEELDNVLGA
Core:
G G G V I Q T I S H E C R M N S W Q F L F T C C S
Core with dehydrations:
G G G V I Q Dhb I Dha H E Cys R M N Dha W Q F L F Dhb Cys Cys Dha

#### MIBiG 3.1 matches for ctg1_4

12.8% BGC0001229 (SBI_06990): Lanthipeptide: SBI-06990 A1 or SBI-06989 A2
7
T I S H E C R M N
15
T+S E C+ N
29
T L S K E C Q P N
37

#### antiSMASH-DB 4.0 matches for ctg1_4

100.0% NZ_VDNV01000006.1: Lanthipeptides: FSV44_RS08765_lanthipeptide
1
G G G V I Q T I S H E C R M N S W Q F L F T C C S
25
G G G V I Q T I S H E C R M N S W Q F L F T C C S
1
G G G V I Q T I S H E C R M N S W Q F L F T C C S
25
80.0% NZ_CP023483.1: Lanthipeptides: CNY62_RS11970_lanthipeptide
1
G G G V I Q T I S H E C R M N S W Q F L F T C C S
25
G G I+T I S H E C M N+W Q F L F T C C S
1
G N G A I R T I S H E C H M N T W Q F L F T C C S
25
80.0% NZ_CP026729.1: Lanthipeptides: BKKJ1_RS07010_lanthipeptide
1
G G G V I Q T I S H E C R M N S W Q F L F T C C
24
G G V+ T I S H E C M N S W Q F L F T C C
1
G N G V V T T I S H E C N M N S W Q F L F T C C
24
with 62 more sequence matches
80.0% NZ_JAEEGA010000010.1: Lanthipeptides: I6N95_RS15660_lanthipeptide
1
G G G V I Q T I S H E C R M N S W Q F L F T C C S
25
G G V I+T I S H E C M N S W Q++F T C C S
1
G N G V I K T I S H E C H M N S W Q W I F T C C S
25
80.0% NZ_JH792236.1 and 1 other:
NZ_JH792236.1 Lanthipeptides: IIM_RS26240_lanthipeptide
Lanthipeptides: IIM_RS26245_lanthipeptide
1
G G G V I Q T I S H E C R M N S W Q F L F T C C S
25
G G V I+T I S H E C M N S W Q +F T C C S
1
G S G V I K T I S H E C H M N S W Q A I F T C C S
25
80.0% NZ_LT732526.1 and 1 other:
NZ_LT732526.1 Lanthipeptides: BQ9856_RS23075_lanthipeptide
Lanthipeptides: BQ9856_RS23080_lanthipeptide
1
G G G V I Q T I S H E C R M N S W Q F L F T C C S
25
G G V I+T I S H E C M N+W Q F+F T C C S
1
G N G V I K T I S H E C A M N T W Q F I F T C C S
25
77.8% NZ_CP069183.1: Lanthipeptides: LLNCDO700_RS13730_lanthipeptide
1
G G G V I Q T I S H E C R M N S W Q F L F T C C S
25
G G V I T I S H E C M N S W Q F+F T C C S
3
G S G V I H T I S H E C N M N S W Q F V F T C C S
27
76.9% NC_012470.1 and 2 others:
NZ_CABY01000005.1 Lanthipeptides: SZBHS5_RS06490_lanthipeptide NZ_CP078012.1 Lanthipeptides: KV238_RS09840_lanthipeptide
Lanthipeptides: SZO_RS04065_lanthipeptide
3
G V I Q T I S H E C R M N S W Q F L F T C C S
25
G I+T I S H E C M N S W Q F L F T C C S
4
G A I K T I S H E C H M N S W Q F L F T C C S
26
76.9% NC_012470.1 and 11 others:
NZ_CABY01000005.1 Lanthipeptides: SZBHS5_RS06485_lanthipeptide NZ_CP029398.1 Lanthipeptides: DF184_RS05185_lanthipeptide NZ_CP029398.1 Lanthipeptides: DF184_RS05180_lanthipeptide NZ_CP078012.1 Lanthipeptides: KV238_RS09835_lanthipeptide NZ_CP078012.1 Lanthipeptides: KV238_RS09830_lanthipeptide NZ_JAFLMI010000009.1 Lanthipeptides: J0638_RS05350_lanthipeptide NZ_JAFLMI010000009.1 Lanthipeptides: J0638_RS05345_lanthipeptide NZ_LR738724.1 Lanthipeptides: GPW69_RS05065_lanthipeptide NZ_LR738724.1 Lanthipeptides: GPW69_RS05060_lanthipeptide NZ_VZNS01000007.1 Lanthipeptides: F6P79_RS05580_lanthipeptide NZ_VZNS01000007.1 Lanthipeptides: F6P79_RS05575_lanthipeptide
Lanthipeptides: SZO_RS04070_lanthipeptide
2
G G V I Q T I S H E C R M N S W Q F L F T C C S
25
G V +T I S H E C M N S W Q F L F T C C S
3
N G V F K T I S H E C H M N S W Q F L F T C C S
26
76.0% NZ_CP084014.1 and 6 others:
NZ_CP084014.1 Lanthipeptides: LCQ72_RS00100_lanthipeptide NZ_CP084014.1 Lanthipeptides: LCQ72_RS00095_lanthipeptide NZ_CP094679.1 Lanthipeptides: K5I24_RS13105_lanthipeptide NZ_JAQEYW010000015.1 Lanthipeptides: PG422_RS12415_lanthipeptide NZ_JAQEYW010000015.1 Lanthipeptides: PG422_RS12410_lanthipeptide NZ_JAQEYW010000015.1 Lanthipeptides: PG422_RS12405_lanthipeptide
Lanthipeptides: LCQ72_RS00105_lanthipeptide
1
G G G V I Q T I S H E C R M N S W Q F L F T C C
24
G G V++T I S H E C M N+W Q F L F T C C
1
G N G V L K T I S H E C N M N T W Q F L F T C C
24
76.0% NZ_GL882519.1: Lanthipeptides: HMPREF9056_RS03330_lanthipeptide
1
G G G V I Q T I S H E C R M N S W Q F L F T C C S
25
G G V T+S H E C M N S W Q F+F T C C S
1
G N G V Y Y T L S H E C H M N S W Q F I F T C C S
25
76.0% NZ_MSRJ01000005.1: Lanthipeptides: BKH06_RS03755_lanthipeptide
3
G V I Q T I S H E C R M N S W Q F L F T C C S
25
G V+ T I S H E C M N S W Q F+F T C C S
2
G V V T T I S H E C N M N S W Q F I F T C C S
24
72.0% NZ_FOZB01000002.1: Lanthipeptides: BM306_RS07850_lanthipeptide
1
G G G V I Q T I S H E C R M N S W Q F L F T C C S
25
G G V +T I S H E C M N+W F+F T C C S
1
G D G V F R T I S H E C H M N T W M F I F T C C S
25
72.0% NZ_QTVL01000002.1 and 5 others:
NZ_QTVL01000002.1 Lanthipeptides: DWZ44_RS04150_lanthipeptide NZ_QTZB01000015.1 Lanthipeptides: DXC15_RS14340_lanthipeptide NZ_QTZB01000015.1 Lanthipeptides: DXC15_RS14335_lanthipeptide NZ_QUKU01000003.1 Lanthipeptides: DXC27_RS02940_lanthipeptide NZ_QUKU01000003.1 Lanthipeptides: DXC27_RS02935_lanthipeptide
Lanthipeptides: DWZ44_RS04155_lanthipeptide
1
G G G V I Q T I S H E C R M N S W Q F L F T C C
24
G G V +T I S H E C M N+W Q F+F T C C
1
G D G V F R T I S H E C N M N T W Q F I F T C C
24
70.4% NZ_CP046629.1 and 3 others:
NZ_FNJX01000002.1 Lanthipeptides: BLR40_RS05025_lanthipeptide NZ_FNZS01000001.1 Lanthipeptides: BMX70_RS03125_lanthipeptide NZ_FOLK01000002.1 Lanthipeptides: BM262_RS05670_lanthipeptide
Lanthipeptides: GPA00_RS05740_lanthipeptide
1
G G G V I Q T I S H E C R M N S W Q F L F T C C S
25
G G V+ T+S H+C M N S W Q F L F T C C S
3
G S G V V P T V S H D C H M N S W Q F L F T C C S
27
69.2% NC_013928.1 and 8 others:
NC_013928.1 Lanthipeptides: SMUNN2025_RS01700_lanthipeptide NZ_CP023477.1 Lanthipeptides: CO204_RS01885_lanthipeptide NZ_CP050270.1 Lanthipeptides: HB753_RS01090_lanthipeptide NZ_CP050270.1 Lanthipeptides: HB753_RS01080_lanthipeptide NZ_CP061071.1 Lanthipeptides: IBL27_RS01745_lanthipeptide NZ_CP061071.1 Lanthipeptides: IBL27_RS01735_lanthipeptide NZ_JALDUN010000005.1 Lanthipeptides: M1F82_RS07575_lanthipeptide NZ_JALDUN010000005.1 Lanthipeptides: M1F82_RS07565_lanthipeptide
Lanthipeptides: SMUNN2025_RS01710_lanthipeptide
1
G G G V I Q T I S H E C R M N S W Q F L F T C C S
25
G G + T I S H E C R N S W F L T C C S
2
G K G A V G T I S H E C R Y N S W A F L A T C C S
26
69.2% NZ_CP023477.1: Lanthipeptides: CO204_RS01875_lanthipeptide
1
G G G V I Q T I S H E C R M N S W Q F L F T C C S
25
G G + T I S H E C R N S W F L T C C S
2
G K G T V G T I S H E C R Y N S W A F L A T C C S
26
69.2% NZ_JAHBEV010000004.1 and 3 others:
NZ_JAHBEX010000010.1 Lanthipeptides: KII86_RS06785_lanthipeptide NZ_JAHBFD010000039.1 Lanthipeptides: KIJ16_RS07340_lanthipeptide NZ_LN890331.1 Lanthipeptides: LEKG_RS02295_lanthipeptide
Lanthipeptides: KII98_RS01100_lanthipeptide
2
G G V I Q T I S H E C R M N S W Q F L F T C C S
25
G V I T+S H E C M N S W Q F+F T C C+
3
S G V I N T V S H E C N M N S W Q F V F T C C A
26
69.2% NZ_NWMU01000024.1 and 3 others:
NZ_NWMU01000024.1 Lanthipeptides: CO197_RS09145_lanthipeptide NZ_VMMF01000004.1 Lanthipeptides: HT717_RS01575_lanthipeptide NZ_VMMF01000004.1 Lanthipeptides: HT717_RS01570_lanthipeptide
Lanthipeptides: CO197_RS09150_lanthipeptide
2
G G V I Q T I S H E C R M N S W Q F L F T C C S
25
G V +T I S H E C M N S+Q F F T C C S
3
N G V F K T I S H E C H M N S F Q F F F T C C S
26
68.0% NZ_AP025017.1: Lanthipeptides: MANAM107_RS05920_lanthipeptide
2
G G V I Q T I S H E C R M N S W Q F L F T C C S
25
G V I T I S H E C +N+W F F T C C S
1
N G V I T T I S H E C H L N T W A F A F T C C S
24
68.0% NZ_CP018188.1 and 17 others:
NZ_CP018188.1 Lanthipeptides: BSR19_RS11175_lanthipeptide NZ_CP066093.1 Lanthipeptides: I6I02_RS07300_lanthipeptide NZ_CP066093.1 Lanthipeptides: I6I02_RS07295_lanthipeptide NZ_JALDUD010000010.1 Lanthipeptides: M1G10_RS09705_lanthipeptide NZ_JALDUD010000010.1 Lanthipeptides: M1G10_RS09700_lanthipeptide NZ_JAQDVH010000019.1 Lanthipeptides: PGU04_RS09300_lanthipeptide NZ_JAQDVH010000019.1 Lanthipeptides: PGU04_RS09295_lanthipeptide NZ_JAQDVH010000019.1 Lanthipeptides: PGU04_RS09300_lanthipeptide NZ_JAQDVH010000019.1 Lanthipeptides: PGU04_RS09295_lanthipeptide NZ_JAQMJT010000006.1 Lanthipeptides: PNU26_RS06585_lanthipeptide NZ_JAQMJT010000006.1 Lanthipeptides: PNU26_RS06580_lanthipeptide NZ_JAQMJT010000006.1 Lanthipeptides: PNU26_RS06585_lanthipeptide NZ_JAQMJT010000006.1 Lanthipeptides: PNU26_RS06580_lanthipeptide NZ_KV832031.1 Lanthipeptides: HMPREF2637_RS05120_lanthipeptide NZ_KV832031.1 Lanthipeptides: HMPREF2637_RS05115_lanthipeptide NZ_PKIA01000004.1 Lanthipeptides: CYK22_RS04335_lanthipeptide NZ_PKIA01000004.1 Lanthipeptides: CYK22_RS04330_lanthipeptide
Lanthipeptides: BSR19_RS11180_lanthipeptide
1
G G G V I Q T I S H E C R M N S W Q F L F T C C S
25
G G V +T I S H E C +N+W F L T C C S
1
G N G V F K T I S H E C H L N T W A F L A T C C S
25
68.0% NZ_CP031746.1: Lanthipeptides: DCC27_RS08165_lanthipeptide
3
G V I Q T I S H E C R M N S W Q F L F T C C S
25
G V I T++H E C M N S W Q L T C C S
2
G V I S T L T H E C H M N S W Q G L L T C C S
24
68.0% NZ_GL985606.1: Lanthipeptides: HMPREF9062_RS00700_lanthipeptide
1
G G G V I Q T I S H E C R M N S W Q F L F T C C
24
G G V T I S H E C N S W F+F T C C
1
G N G V F H T I S H E C Y Y N S W A F I F T C C
24
68.0% NZ_WBPF01000002.1: Lanthipeptides: F8162_RS00195_lanthipeptide
3
G V I Q T I S H E C R M N S W Q F L F T C C S
25
G T I S H E C N+W Q F L F T C C S
3
G Q F D T I S H E C H W N T W Q F L F T C C S
25
64.0% NZ_CP046956.1: Lanthipeptides: ERJ70_RS03695_lanthipeptide
2
G G V I Q T I S H E C R M N S W Q F L F T C C
24
G I T+S H E C M N+W Q F+F T C C
1
D G A I S T V S H E C H M N T W Q F I F T C C
23
64.0% NZ_CP083176.1 and 4 others:
NZ_JABUHD010000002.1 Lanthipeptides: HRR08_RS05415_lanthipeptide NZ_LSLF01000001.1 Lanthipeptides: AXE72_RS04025_lanthipeptide NZ_PNHB01000001.1 Lanthipeptides: CJ210_RS02800_lanthipeptide NZ_QJVA01000001.1 Lanthipeptides: D0T19_RS02755_lanthipeptide
Lanthipeptides: K9E37_RS06280_lanthipeptide
1
G G G V I Q T I S H E C R M N S W Q F L F T C C
24
G G V+ T++H E C M N+W Q F L T C C
1
G D G V M H T L T H E C H M N T W Q F L L T C C
24
63.0% NZ_CP051645.1 and 2 others:
NZ_JAKVFF010000018.1 Lanthipeptides: MKR34_RS11425_lanthipeptide NZ_VDOJ01000018.1 Lanthipeptides: FSV48_RS11975_lanthipeptide
Lanthipeptides: HHJ99_RS13350_lanthipeptide
2
G G V I Q T I S H E C R M N S W Q F L F T C C S
25
G V I T+S H+C M N S+Q F+F T C C S
4
S G V I P T V S H D C H M N S F Q F V F T C C S
27
61.5% NZ_ALSD01000046.1 and 49 others:
NZ_CAAHGW010000010.1 Lanthipeptides: E9435_RS08890_lanthipeptide NZ_CAAHHE010000002.1 Lanthipeptides: E9499_RS02935_lanthipeptide NZ_CAAHHF010000009.1 Lanthipeptides: E9478_RS08685_lanthipeptide NZ_CAAHHF010000009.1 Lanthipeptides: E9478_RS08680_lanthipeptide NZ_CAAHHN010000003.1 Lanthipeptides: E9502_RS05700_lanthipeptide NZ_CAAHHU010000009.1 Lanthipeptides: E9510_RS08730_lanthipeptide NZ_CAAHHU010000009.1 Lanthipeptides: E9510_RS08725_lanthipeptide NZ_CAAHHW010000012.1 Lanthipeptides: E9525_RS08980_lanthipeptide NZ_CAAHHW010000012.1 Lanthipeptides: E9525_RS08975_lanthipeptide NZ_CAAHIB010000001.1 Lanthipeptides: E9539_RS01070_lanthipeptide NZ_CAAHIV010000024.1 Lanthipeptides: E9612_RS09265_lanthipeptide NZ_CAAHIV010000024.1 Lanthipeptides: E9612_RS09260_lanthipeptide NZ_CAAHKK010000019.1 Lanthipeptides: E9649_RS08765_lanthipeptide NZ_CAAHKK010000019.1 Lanthipeptides: E9649_RS08760_lanthipeptide NZ_CAAHKP010000014.1 Lanthipeptides: E9652_RS08915_lanthipeptide NZ_CAAHKP010000014.1 Lanthipeptides: E9652_RS08910_lanthipeptide NZ_CAAHKQ010000003.1 Lanthipeptides: E9664_RS02170_lanthipeptide NZ_CAAHKY010000014.1 Lanthipeptides: E9668_RS09655_lanthipeptide NZ_CAAHLP010000002.1 Lanthipeptides: E9684_RS03455_lanthipeptide NZ_CAAHLP010000002.1 Lanthipeptides: E9684_RS03450_lanthipeptide NZ_CAAHQE010000012.1 Lanthipeptides: E9931_RS08825_lanthipeptide NZ_CAAHQE010000012.1 Lanthipeptides: E9931_RS08820_lanthipeptide NZ_CAAHRY010000002.1 Lanthipeptides: E9986_RS03170_lanthipeptide NZ_CAAIES010000002.1 Lanthipeptides: FAH15_RS02470_lanthipeptide NZ_CAAIIA010000012.1 Lanthipeptides: FAH55_RS08470_lanthipeptide NZ_CAAIIA010000012.1 Lanthipeptides: FAH55_RS08465_lanthipeptide NZ_CAAIJM010000015.1 Lanthipeptides: FAI23_RS09580_lanthipeptide NZ_CAAINV010000013.1 Lanthipeptides: FAI86_RS09035_lanthipeptide NZ_CAAINV010000013.1 Lanthipeptides: FAI86_RS09030_lanthipeptide NZ_CAAIRS010000012.1 Lanthipeptides: FAK24_RS08495_lanthipeptide NZ_CAAIRS010000012.1 Lanthipeptides: FAK24_RS08490_lanthipeptide NZ_CAAJFI010000013.1 Lanthipeptides: FAP60_RS08505_lanthipeptide NZ_CAAJFI010000013.1 Lanthipeptides: FAP60_RS08500_lanthipeptide NZ_CAJHJS010000009.1 Lanthipeptides: JMX87_RS06790_lanthipeptide NZ_CAJHJS010000009.1 Lanthipeptides: JMX87_RS06785_lanthipeptide NZ_CM001076.1 Lanthipeptides: SDD27957_RS04310_lanthipeptide NZ_CM001076.1 Lanthipeptides: SDD27957_RS04305_lanthipeptide NZ_CP035426.1 Lanthipeptides: ETT73_RS02595_lanthipeptide NZ_CP035426.1 Lanthipeptides: ETT73_RS02590_lanthipeptide NZ_CP035428.1 Lanthipeptides: ETT71_RS02815_lanthipeptide NZ_CP035437.1 Lanthipeptides: ETT62_RS06680_lanthipeptide NZ_CP035437.1 Lanthipeptides: ETT62_RS06675_lanthipeptide NZ_CP035443.1 Lanthipeptides: ETT56_RS07265_lanthipeptide NZ_GL636070.1 Lanthipeptides: HMPREF9171_RS105315_lanthipeptide NZ_LR793258.1 Lanthipeptides: HV369_RS03145_lanthipeptide NZ_LR793258.1 Lanthipeptides: HV369_RS03140_lanthipeptide NZ_LS483425.1 Lanthipeptides: DQN36_RS06755_lanthipeptide NZ_LS483425.1 Lanthipeptides: DQN36_RS06750_lanthipeptide NZ_LT545678.1 Lanthipeptides: BJR96_RS07040_lanthipeptide
Lanthipeptides: SAG0161_RS120605_lanthipeptide
3
G V I Q T I S H E C R M N S W Q F L F T C C S
25
G V +T I S H E C +N+W F L T C C S
4
G V F K T I S H E C H L N T W A F L A T C C S
26
61.5% NZ_MSRU01000008.1: Lanthipeptides: BKH03_RS04355_lanthipeptide
1
G G G V I Q T I S H E C R M N S W Q F L F T C C S
25
G G V +I+H E C M N S Q L T C C S
2
G D G V K W S I T H E C Y M N S L Q V L L T C C S
26
60.0% NC_013928.1 and 4 others:
NZ_CP023477.1 Lanthipeptides: CO204_RS01880_lanthipeptide NZ_CP050270.1 Lanthipeptides: HB753_RS01085_lanthipeptide NZ_CP061071.1 Lanthipeptides: IBL27_RS01740_lanthipeptide NZ_JALDUN010000005.1 Lanthipeptides: M1F82_RS07570_lanthipeptide
Lanthipeptides: SMUNN2025_RS01705_lanthipeptide
1
G G G V I Q T I S H E C R M-N S W Q F L F T C
23
G G V I+T I+ C R M N+ Q L F T C
2
G N G V I R T I T Q G C R M P N N M Q V L F T C
25
60.0% NZ_CAAHHE010000002.1 and 13 others:
NZ_CAAHHF010000009.1 Lanthipeptides: E9478_RS08675_lanthipeptide NZ_CAAHHN010000003.1 Lanthipeptides: E9502_RS05705_lanthipeptide NZ_CAAHHU010000009.1 Lanthipeptides: E9510_RS08735_lanthipeptide NZ_CAAHHW010000012.1 Lanthipeptides: E9525_RS08985_lanthipeptide NZ_CAAHIB010000001.1 Lanthipeptides: E9539_RS01075_lanthipeptide NZ_CAAHIV010000024.1 Lanthipeptides: E9612_RS09255_lanthipeptide NZ_CAAHKP010000014.1 Lanthipeptides: E9652_RS08920_lanthipeptide NZ_CAAHKY010000014.1 Lanthipeptides: E9668_RS09650_lanthipeptide NZ_CAAHLP010000002.1 Lanthipeptides: E9684_RS03445_lanthipeptide NZ_CAAHRY010000002.1 Lanthipeptides: E9986_RS03175_lanthipeptide NZ_CAAIES010000002.1 Lanthipeptides: FAH15_RS02475_lanthipeptide NZ_CAAIJM010000015.1 Lanthipeptides: FAI23_RS09585_lanthipeptide NZ_CAAIRS010000012.1 Lanthipeptides: FAK24_RS08485_lanthipeptide
Lanthipeptides: E9499_RS02930_lanthipeptide
1
G G G V I Q T I S H E C R M N S W Q F L F T C C
24
G G + T I S E C R N S Q +F T C C
1
G G H G V N T I S A E C R W N S L Q A I F T C C
24
60.0% NZ_CP072384.1: Lanthipeptides: J5A65_RS01395_lanthipeptide
1
G G G V I Q T I S H E C R M N S W Q F L F T C C
24
G G V+ T++H E C M N S W Q+ F C C
1
G R G V V P T V T H E C H M N S W Q W F F G C C
24
59.3% NZ_CP044492.1 and 1 other:
NZ_CP066294.2 Lanthipeptides: IGS65_RS08185_lanthipeptide
Lanthipeptides: FSA31_RS00605_lanthipeptide
3
G V I Q T I S H E C R M N S W Q F L F T C C
24
G V+ T+S+E C R M N S W Q +F T C C
6
G V V P T V S Y E C R M N S W Q H V F T C C
27
59.3% NZ_CP046304.1: Lanthipeptides: FOC54_RS00030_lanthipeptide
2
G G V I Q T I S H E C R M N S W Q F L F T C C S
25
G V I T+S H+C M N++Q F+F T C C S
4
S G V I P T V S H D C H M N T F Q F M F T C C S
27
59.3% NZ_CP049223.1 and 4 others:
NZ_CP049225.1 Lanthipeptides: G6Z85_RS06555_lanthipeptide NZ_CP049228.1 Lanthipeptides: G6Z83_RS06555_lanthipeptide NZ_JAKWZB010000003.1 Lanthipeptides: MMO78_RS01405_lanthipeptide NZ_PNGO01000002.1 Lanthipeptides: CJ224_RS02730_lanthipeptide
Lanthipeptides: G6Z86_RS06445_lanthipeptide
3
G V I Q T I S H E C R M N S W Q F L F T C C
24
G V+ T+S H E C R M N S+Q +F T C C
6
G V L P T V S H E C R M N S F Q H I F T C C
27
59.3% NZ_FNUH01000004.1 and 1 other:
NZ_FOGM01000011.1 Lanthipeptides: BMX20_RS07220_lanthipeptide
Lanthipeptides: BLU50_RS05815_lanthipeptide
3
G V I Q T I S H E C R M N S W Q F L F T C C
24
G V+ T+S+E C R M N S W Q +F T C C
6
G V V P T V S Y E C R M N S W Q S I F T C C
27
57.7% NZ_CAAHKQ010000003.1: Lanthipeptides: E9664_RS02165_lanthipeptide
3
G V I Q T I S H E C R M N S W Q F L F T C C S
25
G V +T I S H E C +N+W F L C C S
4
G V F K T I S H E C H L N T W A F L A I C C S
26
57.7% NZ_CP060646.1: Lanthipeptides: H7789_RS06845_lanthipeptide
3
G V I Q T I S H E C R M N S W Q F L F T C C S
25
G V +T I S H E C +N+W L T C C S
4
G V F K T I S H E C H L N T W A S L A T C C S
26
56.0% NC_012470.1 and 15 others:
NZ_CABY01000005.1 Lanthipeptides: SZBHS5_RS10120_lanthipeptide NZ_CP018188.1 Lanthipeptides: BSR19_RS11185_lanthipeptide NZ_CP029398.1 Lanthipeptides: DF184_RS05190_lanthipeptide NZ_CP066093.1 Lanthipeptides: I6I02_RS07305_lanthipeptide NZ_CP078012.1 Lanthipeptides: KV238_RS09825_lanthipeptide NZ_JAFLMI010000009.1 Lanthipeptides: J0638_RS05340_lanthipeptide NZ_JALDUD010000010.1 Lanthipeptides: M1G10_RS09695_lanthipeptide NZ_JAQDVH010000019.1 Lanthipeptides: PGU04_RS09305_lanthipeptide NZ_JAQDVH010000019.1 Lanthipeptides: PGU04_RS09305_lanthipeptide NZ_JAQMJT010000006.1 Lanthipeptides: PNU26_RS06590_lanthipeptide NZ_JAQMJT010000006.1 Lanthipeptides: PNU26_RS06590_lanthipeptide NZ_KV832031.1 Lanthipeptides: HMPREF2637_RS10860_lanthipeptide NZ_LR738724.1 Lanthipeptides: GPW69_RS05070_lanthipeptide NZ_PKIA01000004.1 Lanthipeptides: CYK22_RS04325_lanthipeptide NZ_VZNS01000007.1 Lanthipeptides: F6P79_RS05570_lanthipeptide
Lanthipeptides: SZO_RS10260_lanthipeptide
1
G G G V I Q T I S H E C R M N S W Q F L F T C C
24
G + T I S E C R N S Q +F T C C
1
A G H G V N T I S A E C R W N S L Q A I F T C C
24
56.0% NZ_CAAHGW010000010.1 and 10 others:
NZ_CAAHKK010000019.1 Lanthipeptides: E9649_RS08770_lanthipeptide NZ_CAAHKQ010000003.1 Lanthipeptides: E9664_RS02160_lanthipeptide NZ_CAAHQE010000012.1 Lanthipeptides: E9931_RS08815_lanthipeptide NZ_CAAIIA010000012.1 Lanthipeptides: FAH55_RS08475_lanthipeptide NZ_CAAINV010000013.1 Lanthipeptides: FAI86_RS09025_lanthipeptide NZ_CAAJFI010000013.1 Lanthipeptides: FAP60_RS08495_lanthipeptide NZ_CP035426.1 Lanthipeptides: ETT73_RS02600_lanthipeptide NZ_CP035437.1 Lanthipeptides: ETT62_RS06670_lanthipeptide NZ_CP035443.1 Lanthipeptides: ETT56_RS07260_lanthipeptide NZ_LS483425.1 Lanthipeptides: DQN36_RS06745_lanthipeptide
Lanthipeptides: E9435_RS08895_lanthipeptide
2
G G V I Q T I S H E C R M N S W Q F L F T C C
24
G + T I S E C R N S Q +F T C C
2
G H G V N T I S A E C R W N S L Q A I F T C C
24
56.0% NZ_MSRJ01000005.1: Lanthipeptides: BKH06_RS03750_lanthipeptide
1
G G G V I Q T I S H E C R M N S W Q F L F T C C S
25
G G V T +H E C N S+ F T C C S
1
G N G V F Y T F T H E C N T N S F Y V A F T C C S
25
52.0% NC_013928.1 and 4 others:
NZ_CP023477.1 Lanthipeptides: CO204_RS01890_lanthipeptide NZ_CP050270.1 Lanthipeptides: HB753_RS01095_lanthipeptide NZ_CP061071.1 Lanthipeptides: IBL27_RS01750_lanthipeptide NZ_JALDUN010000005.1 Lanthipeptides: M1F82_RS07560_lanthipeptide
Lanthipeptides: SMUNN2025_RS09965_lanthipeptide
1
G G G V I Q T I S H E C R M N S W Q F L F T C C
24
G G T I S +C R N S Q +F+C C
1
G G R A S N T I S S D C R W N S L Q A I F S C C
24
52.0% NZ_ALSD01000046.1 and 5 others:
NZ_CAJHJS010000009.1 Lanthipeptides: JMX87_RS06795_lanthipeptide NZ_CM001076.1 Lanthipeptides: SDD27957_RS10995_lanthipeptide NZ_GL636070.1 Lanthipeptides: HMPREF9171_RS1000000113590_lanthipeptide NZ_LR793258.1 Lanthipeptides: HV369_RS03150_lanthipeptide NZ_LT545678.1 Lanthipeptides: BJR96_RS11590_lanthipeptide
Lanthipeptides: SAG0161_RS1000000124770_lanthipeptide
1
G G G V I Q T I S H E C R M N S W Q F L F T C C
24
G + T I S E C R N S Q +F+C C
1
A G H G V N T I S A E C R W N S L Q A I F S C C
24
52.0% NZ_NWMU01000024.1 and 1 other:
NZ_VMMF01000004.1 Lanthipeptides: HT717_RS01580_lanthipeptide
Lanthipeptides: CO197_RS09155_lanthipeptide
5
I Q T I S H E C R M N S W Q F L F T C C
24
+ T I S E C R N S Q +F T C C
6
V N T I S A E C R W N S L Q A I F T C C
25
51.9% NZ_CP037940.1: Lanthipeptides: EQG49_RS07315_lanthipeptide
1
G G G V I Q T I S H E C R M N S W Q F L F T C C
24
G G V I+T++H E C+M N++Q + T C C
4
G S G V I K T L T H E C K M N T Y Q A I L T C C
27
48.0% NZ_LR134406.1: Lanthipeptides: EL272_RS00695_lanthipeptide
1
G G G V I Q T I S H E C R M N S W Q F L F T C C
24
G G I + +H E C N+ L F T C C
1
G W G S I F S F T H E C N T N T M T Q L F T C C
24
40.7% NZ_CP086142.1 and 3 others:
NZ_CP086142.1 Lanthipeptides: LL065_RS25460_lanthipeptide NZ_CP086142.1 Lanthipeptides: LL065_RS25455_lanthipeptide NZ_CP086142.1 Lanthipeptides: LL065_RS25450_lanthipeptide
Lanthipeptides: LL065_RS25465_lanthipeptide
1
G G G V I Q T I S H E C R M N S
16
G G G V I T +H E C N S
1
G G G V I T T F T H E C Y Y N S
16
40.0% NC_015760.1 and 5 others:
NZ_CAJHJN010000010.1 Lanthipeptides: JMZ68_RS09030_lanthipeptide NZ_JACLQK010000036.1 Lanthipeptides: H7U04_RS11500_lanthipeptide NZ_JADPEB010000003.1 Lanthipeptides: I4U26_RS02800_lanthipeptide NZ_JAQCST010000021.1 Lanthipeptides: PGZ09_RS09470_lanthipeptide NZ_OU540596.1 Lanthipeptides: JQ838_RS05640_lanthipeptide
Lanthipeptides: SALIVB_RS03310_lanthipeptide
1
G G G V I Q T I S H E C R M N S W Q F L F T C C
24
G G V+ T++H E C + +W C C
1
G N G V V L T L T H E C N L A T W T K K L K C C
24
40.0% NZ_CP045267.1 and 1 other:
NZ_CP045267.1 Lanthipeptides: FDZ14_RS00155_lanthipeptide
Lanthipeptides: FDZ14_RS00155_lanthipeptide
1
G G G V I Q T I S H E C R M N S W Q F L F T C C
24
G G V++T + E C + + F F C C
1
G D G V V K T A T S E C Y L G T--F A F A C C
22
40.0% NZ_JAFCGV010000005.1: Lanthipeptides: JQI09_RS04275_lanthipeptide
1
G G G V I Q T I S H E C R M N S W Q F L F T C C
24
G G V++T + E C + + F F C C
1
G D G V V K T A T S E C Y L G T--F A F V C C
22
38.7% NZ_CP034248.1: Lanthipeptides: EIM92_RS14995_lanthipeptide
2
G G V I Q T I S H E C R M N S
16
G G V I T I S H E C N S
7
G G V I C T I S H E C H Y N S
21
37.0% NZ_CP071875.1: Lanthipeptides: J4I02_RS02880_lanthipeptide
2
G G V I Q T I S H E C R M N S W Q F L F T C C
24
G G I T++H E C W ++C C
8
G G A I C T L T H E C A G T H W---Y S C C
27
37.0% NZ_CP077726.1 and 12 others:
NZ_CP077726.1 Lanthipeptides: KTC92_RS18420_lanthipeptide NZ_CP077726.1 Lanthipeptides: KTC92_RS18415_lanthipeptide NZ_CP077726.1 Lanthipeptides: KTC92_RS18410_lanthipeptide NZ_CP077726.1 Lanthipeptides: KTC92_RS18405_lanthipeptide NZ_CP086248.1 Lanthipeptides: LL036_RS19070_lanthipeptide NZ_CP086248.1 Lanthipeptides: LL036_RS19065_lanthipeptide NZ_CP086248.1 Lanthipeptides: LL036_RS19060_lanthipeptide NZ_CP086248.1 Lanthipeptides: LL036_RS19055_lanthipeptide NZ_CP086248.1 Lanthipeptides: LL036_RS19050_lanthipeptide NZ_CP086248.1 Lanthipeptides: LL036_RS19045_lanthipeptide NZ_CP086248.1 Lanthipeptides: LL036_RS19040_lanthipeptide NZ_CP086248.1 Lanthipeptides: LL036_RS19035_lanthipeptide
Lanthipeptides: KTC92_RS18425_lanthipeptide
1
G G G V I Q T I S H E C R M N S
16
G G V I T +H E C N S
1
G N G V I T T F T H E C Y Y N S
16
34.6% NZ_CP117876.1: Lanthipeptides: PQ460_RS01735_lanthipeptide
1
G G G V I Q T I S H E C R M N S W Q F L F T C C
24
G G V++T + E C + + F+ C C
1
G D G V V K T A T S E C Y L G T V A F I--C C
22
32.0% NZ_CP060646.1: Lanthipeptides: H7789_RS06840_lanthipeptide
1
G G G V I Q T I S H E C R
13
G G + T I S E C R
1
G G H G V N T I S A E C R
13
29.4% NZ_CAKMMP010000011.1 and 5 others:
NZ_CP018620.1 Lanthipeptides: BS614_RS05680_lanthipeptide NZ_CP062165.1 Lanthipeptides: JNUCC31_RS16755_lanthipeptide NZ_FMVM01000006.1 Lanthipeptides: BLQ13_RS10365_lanthipeptide NZ_RIAS01000010.1 Lanthipeptides: EC604_RS18225_lanthipeptide NZ_VEJI01000010.1 Lanthipeptides: FS576_RS22075_lanthipeptide
Lanthipeptides: L6H98_RS19925_lanthipeptide
2
G G V I Q T I S H E C R M N S
16
G G V T+S H E C N S
10
G G V F C T V S H E C H Y N S
24
26.9% NZ_JALASB010000016.1 and 3 others:
NZ_JALASR010000012.1 Lanthipeptides: MOD87_RS16305_lanthipeptide NZ_JALAUW010000005.1 Lanthipeptides: MOE83_RS03160_lanthipeptide NZ_JALAXQ010000010.1 Lanthipeptides: MOF24_RS12150_lanthipeptide
Lanthipeptides: MOD42_RS18070_lanthipeptide
1
G G G V I Q T I S H E C
12
G G G + T I+ E C
13
G G G G V C T I T S E C
24
24.0% NZ_AP018365.1: Lanthipeptides: RVR_RS00125_lanthipeptide
16
S W Q F L F T C C
24
S W Q F+C C
5
S W Q G S F S C C
13
24.0% NZ_FONG01000023.1 and 4 others:
NZ_FONG01000023.1 Lanthipeptides: BM076_RS29665_lanthipeptide NZ_FONG01000023.1 Lanthipeptides: BM076_RS29665_lanthipeptide NZ_FONG01000023.1 Lanthipeptides: BM076_RS29665_lanthipeptide NZ_FONG01000023.1 Lanthipeptides: BM076_RS29665_lanthipeptide
Lanthipeptides: BM076_RS29665_lanthipeptide
16
S W Q F L F T C C
24
S W Q+ F+C C
5
S W Q W S F S C C
13
21.2% NZ_AP024169.1: Lanthipeptides: bsdtb5_RS06110_lanthipeptide
3
G V I Q T I S H E C R M N S
16
G T I S+E C N+
15
G G F P T I S Y E C T S N N
28
21.2% NZ_AP024169.1: Lanthipeptides: bsdtb5_RS06105_lanthipeptide
3
G V I Q T I S H E C R M N S
16
G + T I S+E C N+
15
G R M P T I S Y E C T S N N
28
20.0% NZ_AP018365.1: Lanthipeptides: RVR_RS00130_lanthipeptide
14
M N S W Q F L F T C C S
25
+ S W+ F+C C
3
I G S W E G T F S C C D
14
19.4% NZ_CP102975.1 and 1 other:
NZ_FMOE01000002.1 Lanthipeptides: BJT27_RS07805_lanthipeptide
Lanthipeptides: NW953_RS00170_lanthipeptide
3
G V I Q T I S H E C
12
G + T+S H E C
16
G K L C T V S H E C
25
15.2% NZ_AP024169.1: Lanthipeptides: bsdtb5_RS06100_lanthipeptide
3
G V I Q T I S H E C
12
G + T+S+E C
15
G A V P T L S Y E C
24
6.6% NZ_CP110813.1: Lanthipeptides: BV903_RS23420_lanthipeptide
10
H E C R M N S W Q F L F T C
23
++C R +W+ + C
29
Y Q C R G G A W R L I A V C
42

#### Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine
Lanthipeptides
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists the number of lanthionine bridges, possible molecular weights, and the scores for cleavage site prediction and RODEO.

ctg1_4 - Class II
  Cleavage pHMM score: 5.20
  RODEO score: 0
  Monoisotopic mass: 2713.2 Da
  Molecular weight: 2715.1 Da
  Number of bridges: 3
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    2733.1 Da N = 1
    2751.1 Da N = 2

gnlProkkaHDCEGNDM_1 - Region 2 - NRPS,transAT-PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 16,225 - 74,622 nt. (total: 58,398 nt) Show pHMM detection rules used
transAT-PKS: (cds(PKS_AT and not (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) and (cds(ATd and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) or cds(tra_KS and PP-binding)))
NRPS: cds(Condensation and (AMP-binding or A-OX))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
NRPS/PKS domains
KnownClusterBlast
NRPS/PKS modules
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A domain glossary is available here, and an explanation of the visualisation is available here.
Selected features only
Show module domains
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Module view
Shows module structures for each candidate cluster in NRPS and PKS regions.
Genes are shown in predicted order, and are only present when containing at least one complete module.
A domain glossary is available here, and an explanation of the visualisation is available here.
Legend
NRPS/PKS products
NRPS/PKS substrates
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 2, location 16224 - 74622:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (X - mal) + (Cys) + (ohmal)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS substrate predictions
Shows the predicted substrates for each adenylation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg1_38: X
  AMP-binding (11..360): X
  nrpys: Phe, Trp
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
    Large clusters prediction:
      N/A
    Small clusters prediction:
      Unpolar aromatic ring (Phe, Trp)
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      IPWTILDTLK
    Nearest Stachelhaus code(s):
      3,4-dohBza MPWAIGDVLK (47% 8Å match)
    Stachelhaus code match:
      60% (weak)
ctg1_39: Cys
  Search NORINE for peptide: strict or relaxed
  AMP-binding (824..1226): Cys
  nrpys: Cys
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
    Large clusters prediction:
      Polar, uncharged (aliphatic with -SH) (Cys)
    Small clusters prediction:
      Polar, uncharged (aliphatic with -SH) (Cys)
    Single AA prediction:
      Polar, uncharged (aliphatic with -SH) (Cys)
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DLFNLSLVWK
    Nearest Stachelhaus code(s):
      Cys DLFNLSLVWK (76% 8Å match)
    Stachelhaus code match:
      100% (strong)
ctg1_43: mal
  PKS_AT (6..282): mal
  ATSignature: Malonyl-CoA
  Top 3 matches:
    Malonyl-CoA: 79.2%
    inactive: 70.8%
  minowa: Malonyl-CoA
  Prediction, score:
    Malonyl-CoA: 67.0
    inactive: 35.5
    Methoxymalonyl-CoA: 15.9
    Methylmalonyl-CoA: 11.2
    trans-1,2-CPDA: 0.0
    fatty_acid: 0.0
    Propionyl-CoA: 0.0
    Isobutyryl-CoA: 0.0
    Ethylmalonyl-CoA: 0.0
    CHC-CoA: 0.0
    Benzoyl-CoA: 0.0
    Acetyl-CoA: 0.0
    3-Methylbutyryl-CoA: 0.0
    2-Methylbutyryl-CoA: 0.0

gnlProkkaHDCEGNDM_1 - Region 3 - lanthipeptide-class-ii
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 160,394 - 181,216 nt. (total: 20,823 nt) Show pHMM detection rules used
Region on contig edge.
lanthipeptide-class-ii: cds(LANC_like and DUF4135)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
KnownClusterBlast
Lanthipeptides
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Lanthipeptide predictions
Shows the possible core peptides for each biosynthetic enzyme.
Includes CompaRiPPson results for any available databases, with a detailed explanation here.

#### Lanthipeptide(s) for ctg1_160

ctg1_159
Leader:
MKNSKDILNNAIEEVSEKELMEVAGG
Core:
K R G T G W F A T I T D D C P N S V F V C C
Core with dehydrations:
K R G Dhb G W F A Dhb I Dhb D D Cys P N Dha V F V Cys Cys

#### MIBiG 3.1 matches for ctg1_159

13.3% BGC0002110 (QKV49893.1): Lanthipeptide: birimositide
5
G W F A T I T D D C P N
16
G W + P N
17
G W C T L T K E C Q P N
28

#### antiSMASH-DB 4.0 matches for ctg1_159

100.0% NZ_CAJHJN010000010.1 and 4 others:
NZ_CP066093.1 Lanthipeptides: I6I02_RS06995_lanthipeptide NZ_JACLQK010000029.1 Lanthipeptides: H7U04_RS10750_lanthipeptide NZ_JADPEB010000003.1 Lanthipeptides: I4U26_RS02855_lanthipeptide NZ_KV832031.1 Lanthipeptides: HMPREF2637_RS05170_lanthipeptide
Lanthipeptides: JMZ68_RS08975_lanthipeptide
1
K R G T G W F A T I T D D C P N S V F V C C
22
K R G T G W F A T I T D D C P N S V F V C C
1
K R G T G W F A T I T D D C P N S V F V C C
22
90.9% NC_004070.1 and 26 others:
NC_008024.1 Lanthipeptides: MGAS10750_RS08460_lanthipeptide NZ_CAAHHZ010000002.1 Lanthipeptides: E9518_RS02835_lanthipeptide NZ_CAAHIH010000002.1 Lanthipeptides: E9602_RS03585_lanthipeptide NZ_CAAHIO010000002.1 Lanthipeptides: E9584_RS04360_lanthipeptide NZ_CAAHJE010000002.1 Lanthipeptides: E9605_RS03435_lanthipeptide NZ_CAAHJS010000002.1 Lanthipeptides: E9628_RS02300_lanthipeptide NZ_CAAHKC010000012.1 Lanthipeptides: E9636_RS08085_lanthipeptide NZ_CAAHMR010000003.1 Lanthipeptides: E9727_RS05510_lanthipeptide NZ_CAAHQE010000003.1 Lanthipeptides: E9931_RS04945_lanthipeptide NZ_CAAHQG010000004.1 Lanthipeptides: E9903_RS05690_lanthipeptide NZ_CAAIFD010000008.1 Lanthipeptides: FAG63_RS07845_lanthipeptide NZ_CAAJDK010000010.1 Lanthipeptides: FAO79_RS08000_lanthipeptide NZ_CAAJFI010000003.1 Lanthipeptides: FAP60_RS03740_lanthipeptide NZ_CP008926.1 Lanthipeptides: DP15_RS03855_lanthipeptide NZ_CP035434.1 Lanthipeptides: ETT65_RS08240_lanthipeptide NZ_CP035435.1 Lanthipeptides: ETT64_RS07905_lanthipeptide NZ_CP035447.1 Lanthipeptides: ETT52_RS07920_lanthipeptide NZ_CP035449.1 Lanthipeptides: ETT50_RS08255_lanthipeptide NZ_CP035453.1 Lanthipeptides: ETT46_RS08220_lanthipeptide NZ_CP060646.1 Lanthipeptides: H7789_RS07920_lanthipeptide NZ_CP065054.1 Lanthipeptides: I2432_RS09105_lanthipeptide NZ_LRGW01000003.1 Lanthipeptides: AWU01_RS03260_lanthipeptide NZ_LS483298.1 Lanthipeptides: DQM39_RS08650_lanthipeptide NZ_LS483407.1 Lanthipeptides: DQM86_RS08100_lanthipeptide NZ_LS483425.1 Lanthipeptides: DQN36_RS07865_lanthipeptide NZ_LS483430.1 Lanthipeptides: DQN28_RS07600_lanthipeptide
Lanthipeptides: SPYM3_RS08605_lanthipeptide
1
K R G T G W F A T I T D D C P N S V F V C C
22
K+G+G W F A T I T D D C P N S V F V C C
1
K K G S G W F A T I T D D C P N S V F V C C
22
90.9% NZ_PKIA01000004.1: Lanthipeptides: CYK22_RS03780_lanthipeptide
1
K R G T G W F A T I T D D C P N S V F V C C
22
K R G G W A T I T D D C P N S V F V C C
1
K R G P G W I A T I T D D C P N S V F V C C
22
with 60 more sequence matches
86.4% NZ_CAAIJM010000014.1: Lanthipeptides: FAI23_RS09465_lanthipeptide
1
K R G T G W F A T I T D D C P N S V F V C C
22
K+ +G W F A T I T D D C P N S V F V C C
1
K K V S G W F A T I T D D C P N S V F V C C
22
86.4% NZ_CP018188.1 and 1 other:
NZ_VDNV01000006.1 Lanthipeptides: FSV44_RS08680_lanthipeptide
Lanthipeptides: BSR19_RS10820_lanthipeptide
1
K R G T G W F A T I T D D C P N S V F V C C
22
K R G G W A T I T D D C P N S+F V C C
1
K R G P G W I A T I T D D C P N S I F V C C
22
81.8% NZ_JAQDVH010000019.1 and 3 others:
NZ_JAQDVH010000019.1 Lanthipeptides: PGU04_RS09335_lanthipeptide NZ_JAQMJT010000006.1 Lanthipeptides: PNU26_RS06620_lanthipeptide NZ_JAQMJT010000006.1 Lanthipeptides: PNU26_RS06620_lanthipeptide
Lanthipeptides: PGU04_RS09335_lanthipeptide
1
K R G T G W F A T I T D D C P N S V F V C C
22
K+G G W A T I T D D C P N S+F V C C
1
K K G P G W I A T I T D D C P N S I F V C C
22
77.3% NZ_CP048273.1 and 3 others:
NZ_CP048273.1 Lanthipeptides: M654_RS18555_lanthipeptide NZ_LT745776.1 Lanthipeptides: B2C81_RS11280_lanthipeptide NZ_LT745776.1 Lanthipeptides: B2C81_RS11275_lanthipeptide
Lanthipeptides: M654_RS18560_lanthipeptide
3
G T G W F A T I T D D C P N S V F V C C
22
G G W T I T D D C P N S V F V C C
2
G C G W A C T I T D D C P N S V F V C C
21
77.3% NZ_CP048890.1 and 3 others:
NZ_CP071478.1 Lanthipeptides: J0P05_RS32905_lanthipeptide NZ_LUCO01000008.1 Lanthipeptides: BMBG_RS24280_lanthipeptide NZ_NVLN01000014.1 Lanthipeptides: CON11_RS24965_lanthipeptide
Lanthipeptides: BMG_RS30865_lanthipeptide
3
G T G W F A T I T D D C P N S V F V C C
22
G G W T I T D D C P N S V F V C C
2
G C G W S C T I T D D C P N S V F V C C
21
72.7% NZ_CP036073.1 and 11 others:
NZ_CP036073.1 Lanthipeptides: EXW45_RS04930_lanthipeptide NZ_CP036073.1 Lanthipeptides: EXW45_RS04925_lanthipeptide NZ_CP036073.1 Lanthipeptides: EXW45_RS04920_lanthipeptide NZ_CP036073.1 Lanthipeptides: EXW45_RS04915_lanthipeptide NZ_CP036073.1 Lanthipeptides: EXW45_RS04910_lanthipeptide NZ_NUEG01000031.1 Lanthipeptides: CN905_RS18915_lanthipeptide NZ_NUEG01000031.1 Lanthipeptides: CN905_RS18910_lanthipeptide NZ_PVRT01000001.1 Lanthipeptides: C6359_RS05275_lanthipeptide NZ_PVRT01000001.1 Lanthipeptides: C6359_RS05270_lanthipeptide NZ_PVRT01000001.1 Lanthipeptides: C6359_RS05265_lanthipeptide NZ_PVRT01000001.1 Lanthipeptides: C6359_RS05260_lanthipeptide
Lanthipeptides: EXW45_RS04935_lanthipeptide
3
G T G W F A T I T D D C P N S V F V C C
22
G G W T+T D D C P N S V F V C C
2
G C G W L C T V T D D C P N S V F V C C
21
72.7% NZ_JANHJQ010000013.1: Lanthipeptides: NON16_RS14160_lanthipeptide
3
G T G W F A T I T D D C P N S V F V C C
22
G G W T+T D D C P N S V F V C C
2
G C G W S C T V T D D C P N S V F V C C
21
72.7% NZ_MOWR01000001.1: Lanthipeptides: BMI76_RS01705_lanthipeptide
2
R G T G W F A T I T D D C P N S V F V C C
22
R G W T I T D+C P N S V F V C C
1
R W Y G W S F T I T D E C P N S V F V C C
21
72.7% NZ_NIHT01000008.1 and 1 other:
NZ_NIHT01000008.1 Lanthipeptides: CDL23_RS06740_lanthipeptide
Lanthipeptides: CDL23_RS06745_lanthipeptide
2
R G T G W F A T I T D D C P N S V F V C C
22
G+G W T I T D D C P N S+F V C C
2
N G S G W L P T I T D D C P N S I F V C C
22
68.2% NZ_MJEH01000022.1 and 1 other:
NZ_MJEH01000022.1 Lanthipeptides: BFG57_RS18360_lanthipeptide
Lanthipeptides: BFG57_RS18365_lanthipeptide
3
G T G W F A T I T D D C P N S V F V C C
22
G G W +T I T D D C P N S+ V C C
1
G D G W I S T I T D D C P N S I I V C C
20
66.7% NZ_MJEH01000022.1: Lanthipeptides: BFG57_RS09480_lanthipeptide
1
K R G T G W F A T I T D D C P N S V F V C C
22
K G G W +T I T D D C P N S+ V C C
3
K P G D G W I S T I T D D C P N S I I V C C
24
60.9% NZ_BMMB01000007.1 and 1 other:
NZ_BMMB01000007.1 Lanthipeptides: IEX62_RS15675_lanthipeptide
Lanthipeptides: IEX62_RS15680_lanthipeptide
3
G T G W F A T I T D D C P N S V F V C C
22
G G W T+T D D C P N S+ V C C
4
G D G W I T T L T D D C P N S I I V C C
23
50.0% NZ_AULU01000012.1: Lanthipeptides: H580_RS25790_lanthipeptide
1
K R G T G W F A T I T D D C P N S V-F V C C
22
K G G W T T D C P + F C C
2
K D G C G W V C T Y T L D C P G T R W F N C C
24
36.0% NC_013928.1 and 4 others:
NZ_CP023477.1 Lanthipeptides: CO204_RS01880_lanthipeptide NZ_CP050270.1 Lanthipeptides: HB753_RS01085_lanthipeptide NZ_CP061071.1 Lanthipeptides: IBL27_RS01740_lanthipeptide NZ_JALDUN010000005.1 Lanthipeptides: M1F82_RS07570_lanthipeptide
Lanthipeptides: SMUNN2025_RS01705_lanthipeptide
3
G T G W F A T I T D D C--P N S V F V
20
G G T I T C P N++ V
2
G N G V I R T I T Q G C R M P N N M Q V
21
33.3% NZ_CP046629.1 and 3 others:
NZ_FNJX01000002.1 Lanthipeptides: BLR40_RS05025_lanthipeptide NZ_FNZS01000001.1 Lanthipeptides: BMX70_RS03125_lanthipeptide NZ_FOLK01000002.1 Lanthipeptides: BM262_RS05670_lanthipeptide
Lanthipeptides: GPA00_RS05740_lanthipeptide
1
K R G T G W F A T I T D D C P N S----V F V C C
22
K+G+G T++ D C + +F C C
1
K K G S G V V P T V S H D C H M N S W Q F L F T C C
26
33.3% NZ_VATK01000028.1: Lanthipeptides: FDO66_RS19480_lanthipeptide
2
R G T G W F A T I T D D C P N S V F V C
21
R G W + T D C F C
1
R P C G W I C S Y T L D C A W L P F G C
20
32.4% NZ_CM000758.1 and 1 other:
NZ_MOOT01000057.1 Lanthipeptides: BK765_RS20265_lanthipeptide
Lanthipeptides: BTHUR0013_RS15850_lanthipeptide
3
G T G W F A T I T D D C P-N S V F V C
21
G G W A T+T D C P N + C
2
G P G W I A T L T K D C P A N K P Y A C
21
32.4% NZ_CP036100.1 and 1 other:
NZ_CP072062.1 Lanthipeptides: J5V93_RS29280_lanthipeptide
Lanthipeptides: EXW47_RS29185_lanthipeptide
3
G T G W F A T I T D D C P N S V F V C C
22
G G W T+T D C P +V V C
2
G P G W V E T V T K D C P W N V P V A C
21
32.4% NZ_JH792312.1 and 1 other:
NZ_QNRN01000010.1 Lanthipeptides: DET63_RS17570_lanthipeptide
Lanthipeptides: IIG_RS24665_lanthipeptide
3
G T G W F A T I T D D C P N S V F V C C
22
G G W T+T D C P +V V C
2
G P G W V E T L T K D C P W N V P V A C
21
31.8% NZ_AUBN01000022.1: Lanthipeptides: G448_RS16025_lanthipeptide
4
T G W F A T I T D D C P N S V F V C
21
+G W F T+T +C + C
3
S G W F C T L T I E C G T F I C A C
20
31.8% NZ_CP015515.1 and 1 other:
NZ_PSUO01000011.1 Lanthipeptides: C5C18_RS08595_lanthipeptide
Lanthipeptides: A6122_RS12855_lanthipeptide
4
T G W F A T I T D D C P N S V F V C
21
+G W T+T +C V C
3
S G W M C T L T I E C G T V V C A C
20
31.8% NZ_CP036455.1 and 1 other:
NZ_JAODUN010000003.1 Lanthipeptides: BXY51_RS10560_lanthipeptide
Lanthipeptides: EKD16_RS25235_lanthipeptide
4
T G W F A T I T D D C P N S V F V C
21
+G W T+T +C V C
2
S G W V C T L T I E C G T L V C A C
19
31.8% NZ_JAGPXN010000019.1 and 2 others:
NZ_KB895893.1 Lanthipeptides: C569_RS0129325_lanthipeptide NZ_KB900614.1 Lanthipeptides: SALPAC6_RS0114155_lanthipeptide
Lanthipeptides: KBX06_RS22045_lanthipeptide
4
T G W F A T I T D D C P N S V F V C
21
+G W T+T +C V C
2
S G W V C T L T I E C G T V V C A C
19
31.0% NZ_JAGFVL010000062.1: Lanthipeptides: J5J03_RS19425_lanthipeptide
3
G T G W F A T I T D D C P--N S V F V C
21
G G W + T D C N + V C
3
G P G W I P S F T G D C T C D N G I T V C
23
30.0% NZ_CP040409.1 and 4 others:
NZ_CP040414.1 Lanthipeptides: FE331_RS04030_lanthipeptide NZ_CP040415.1 Lanthipeptides: FE330_RS03440_lanthipeptide NZ_CP040417.1 Lanthipeptides: FE328_RS00755_lanthipeptide NZ_CP040424.1 Lanthipeptides: FE321_RS03455_lanthipeptide
Lanthipeptides: FE336_RS03460_lanthipeptide
3
G T G W F A T I T D D C P N S V
18
G G T+T D C P N V
2
G P G L V R T L T K D C P N V V
17
30.0% NZ_CP058255.1: Lanthipeptides: HW369_RS18920_lanthipeptide
9
T I T D D C P N S V F V C C
22
T I T D C P N+V C
4
T I T K D C P N T V S S V C
17
29.4% NZ_CM000748.1 and 1 other:
NZ_JAIPUK010000011.1 Lanthipeptides: K9P71_RS26815_lanthipeptide
Lanthipeptides: BTHUR0003_RS30910_lanthipeptide
3
G T G W F A T I T D D C P N S V F V C C
22
G G W T+T D C P ++ V C
2
G P G W V E T L T K D C P W N M P V A C
21
29.4% NZ_JADNMH010000005.1: Lanthipeptides: I2E99_RS07105_lanthipeptide
1
K R G T G W F A T I T D D C P N S V F V C C
22
K G T I T +C P + V C C
13
K D S C G R R C T I T T E C P I A T V V C C
34
29.4% NZ_KB976276.1: Lanthipeptides: IIC_RS09105_lanthipeptide
3
G T G W F A T I T D D C P N S V F V C C
22
G G W T+T D C P V C
2
G P G W V E T L T K D C P W K Q P V A C
21
28.0% NZ_JHXK01000032.1: Lanthipeptides: T483_RS31035_lanthipeptide
11
T D D C P N S V F V C
21
T C P +V F V C
9
T S L C P T N V F V C
19
27.3% NC_009480.1 and 10 others:
NZ_CP033724.1 Lanthipeptides: EFE39_RS10220_lanthipeptide NZ_CP047051.1 Lanthipeptides: GRD74_RS10365_lanthipeptide NZ_CP047054.1 Lanthipeptides: GRD61_RS10460_lanthipeptide NZ_CP053860.1 Lanthipeptides: DQP62_RS10825_lanthipeptide NZ_CP076352.1 Lanthipeptides: KN218_RS09900_lanthipeptide NZ_CP085137.1 Lanthipeptides: LHJ48_RS10290_lanthipeptide NZ_CP085140.1 Lanthipeptides: LHJ47_RS10305_lanthipeptide NZ_CP095274.1 Lanthipeptides: MU580_RS10460_lanthipeptide NZ_PSTW01000024.1 Lanthipeptides: C5C03_RS09675_lanthipeptide NZ_SISU01000002.1 Lanthipeptides: EOG37_RS09890_lanthipeptide
Lanthipeptides: CMM_RS10575_lanthipeptide
4
T G W F A T I T D D C P N S V F V C
21
+G W T+T +C + C
3
S G W L C T L T I E C G T I I C A C
20
27.3% NC_011900.1 and 3 others:
NZ_CP102135.1 Lanthipeptides: NQZ98_RS01500_lanthipeptide NZ_NCVD01000002.1 Lanthipeptides: B7702_RS00350_lanthipeptide NZ_NCVL01000015.1 Lanthipeptides: B7694_RS04515_lanthipeptide
Lanthipeptides: SPN23F_RS06435_lanthipeptide
1
K R G T G W F A T I T D D C P N S V F V C C
22
+ G T I T +C P F+C C
12
E H S C G R G C T I T T E C P F L T F I C C
33
27.3% NZ_CP028130.1: Lanthipeptides: C7V51_RS14690_lanthipeptide
4
T G W F A T I T D D C P N S V F V C
21
+G W T+T +C + C
3
S G W M C T L T I E C G T I I C A C
20
27.3% NZ_CP061274.1 and 1 other:
NZ_JADKRR010000001.1 Lanthipeptides: ITJ40_RS10085_lanthipeptide
Lanthipeptides: H9X71_RS09850_lanthipeptide
4
T G W F A T I T D D C P N S V F V C
21
+G W T+T +C + C
3
S G W L C T L T I E C G T F I C A C
20
27.3% NZ_FQTY01000002.1: Lanthipeptides: BUB33_RS04605_lanthipeptide
1
K R G T G W F A T I T D D C P N S V F V C C
22
K G T I T +C P + +C C
12
K D S C G H G C T I T T E C P V A T V I C C
33
27.3% NZ_JVCZ01000028.1: Lanthipeptides: ADG88_RS11420_lanthipeptide
5
G W F A T I T D D C P N S V F V C C
22
G T I T +C P F+C C
16
G R G C T I T T E C P F L T F I C C
33
27.3% NZ_LWKZ01000001.1: Lanthipeptides: A6A06_RS41385_lanthipeptide
3
G T G W F A T I T D D C
14
+G+F T I T +C
2
S S G Y F C T I T T E C
13
26.5% NZ_FMVM01000006.1 and 2 others:
NZ_RIAS01000010.1 Lanthipeptides: EC604_RS18225_lanthipeptide NZ_VEJI01000010.1 Lanthipeptides: FS576_RS22075_lanthipeptide
Lanthipeptides: BLQ13_RS10365_lanthipeptide
1
K R G T G W F A T I T D D C------P N S V F V C C
22
K+ G F T++ +C P+S C C
7
K K S G G V F C T V S H E C H Y N S V S P S S W L T C C
34
26.5% NZ_GG666304.1: Lanthipeptides: HMPREF0077_RS09155_lanthipeptide
1
K R G T G W F A T I T D D C P N S V F V C C
22
K G T I T +C P + +C C
13
K D S C G H G C T I T T E C P F A T L I C C
34
26.5% NZ_LR595858.1: Lanthipeptides: FQT45_RS03330_lanthipeptide
1
K R G T G W F A T I T D D C P N S V F V C C
22
K G T I T +C P + +C C
13
K D S C G R G C T I T T E C P I A T I I C C
34
25.9% NZ_CP037940.1: Lanthipeptides: EQG49_RS07315_lanthipeptide
2
R G T G W F A T I T D D C P----N S V F V C C
22
+G+G T+T +C ++ C C
3
K G S G V I K T L T H E C K M N T Y Q A I L T C C
27
25.0% NZ_AXVK01000021.1: Lanthipeptides: K332_RS23905_lanthipeptide
16
N S V F V C C
22
N S+F V C C
5
N S M F V C C
11
24.2% NZ_CP040409.1 and 4 others:
NZ_CP040411.1 Lanthipeptides: FE334_RS06825_lanthipeptide NZ_CP040422.1 Lanthipeptides: FE323_RS09430_lanthipeptide NZ_JH601103.1 Lanthipeptides: HMPREF9703_RS02710_lanthipeptide NZ_NAQX01000046.1 Lanthipeptides: B8A46_RS06295_lanthipeptide
Lanthipeptides: FE336_RS08590_lanthipeptide
1
K R G T G W F A T I T D D C P N S V F V C C
22
+ G T I T +C P C C
12
R H S C G R A C T I T A E C P V F T V A C C
33
23.5% NZ_CM000731.1 and 10 others:
NZ_CP036053.1 Lanthipeptides: EXW64_RS27135_lanthipeptide NZ_CP043834.1 Lanthipeptides: F0362_RS30375_lanthipeptide NZ_JAOPRA010000024.1 Lanthipeptides: OCE16_RS27090_lanthipeptide NZ_KB976667.1 Lanthipeptides: IG5_RS06165_lanthipeptide NZ_LDKD02000003.1 Lanthipeptides: ABH17_RS27060_lanthipeptide NZ_NUAO01000019.1 Lanthipeptides: CN544_RS19345_lanthipeptide NZ_NVFH01000027.1 Lanthipeptides: COL40_RS24675_lanthipeptide NZ_NVHY01000021.1 Lanthipeptides: COM05_RS26660_lanthipeptide NZ_NVOB01000050.1 Lanthipeptides: CON62_RS29235_lanthipeptide NZ_NVOV01000033.1 Lanthipeptides: CON78_RS26470_lanthipeptide
Lanthipeptides: BCERE0020_RS28875_lanthipeptide
3
G T G W F A T I T D D C P
15
G G W T+T D C P
2
G P G W V E T L T K D C P
14
23.5% NZ_CP040409.1 and 4 others:
NZ_CP040414.1 Lanthipeptides: FE331_RS04020_lanthipeptide NZ_CP040415.1 Lanthipeptides: allorf_0721024_0721203_lanthipeptide NZ_CP040417.1 Lanthipeptides: FE328_RS00745_lanthipeptide NZ_CP040424.1 Lanthipeptides: FE321_RS03445_lanthipeptide
Lanthipeptides: FE336_RS03450_lanthipeptide
2
R G T G W F A T I T D D C P N S V
18
+G G T+T D C P +V
1
K G P G L L K T L T K D C P G T V
17
23.5% NZ_JADPCZ010000011.1 and 1 other:
NZ_OW659477.1 Lanthipeptides: NMG62_RS06660_lanthipeptide
Lanthipeptides: I4W03_RS06785_lanthipeptide
1
K R G T G W F A T I T D D C P N S V F V C C
22
K G T+T +C P + +C C
13
K H S C G R A C T V T T E C P I A T I I C C
34
23.5% NZ_KB976165.1: Lanthipeptides: ICC_RS24850_lanthipeptide
3
G T G W F A T I T D D C P N
16
G G W T+T D C P
2
G P G W V E T L T K D C P G
15
23.5% NZ_LMFO01000023.1: Lanthipeptides: allorf_629531_629758_lanthipeptide
1
K R G T G W F A T I T D D C P N S V F V C
21
++ G F T T +C P F C
14
Q K S C G N F C T F T T E C P F L S F C C
34
22.2% NZ_NUQX01000026.1: Lanthipeptides: COE81_RS20200_lanthipeptide
7
F A T I T D-D C P N S V F V C
21
+ T I D D P N S +C
1
Y M T I I D I D P P N S S I I C
16
21.4% NZ_FMXP01000004.1: Lanthipeptides: BLQ04_RS01515_lanthipeptide
5
G W F A T I T D D C P N S V F V C C
22
G W T+T D C P N + C
4
G W I K T L T K D C P N V I S S I C
21
21.2% NC_017621.1 and 16 others:
NZ_CP039462.1 Lanthipeptides: E8M06_RS05390_lanthipeptide NZ_JABTZM010000032.1 Lanthipeptides: HRQ47_RS09675_lanthipeptide NZ_JAEVFQ010000010.1 Lanthipeptides: JNO64_RS06375_lanthipeptide NZ_JAFFHD010000003.1 Lanthipeptides: JN532_RS02075_lanthipeptide NZ_JAGFVG010000007.1 Lanthipeptides: J5581_RS04225_lanthipeptide NZ_JAIJZO010000001.1 Lanthipeptides: K5Q34_RS00965_lanthipeptide NZ_JAIMDS010000024.1 Lanthipeptides: K6V32_RS10650_lanthipeptide NZ_JAJUWV010000001.1 Lanthipeptides: LZF89_RS05505_lanthipeptide NZ_JAMDIS010000017.1 Lanthipeptides: M5P45_RS08180_lanthipeptide NZ_JAMYIU010000001.1 Lanthipeptides: NKE44_RS01780_lanthipeptide NZ_JAMYIX010000001.1 Lanthipeptides: NKE54_RS02675_lanthipeptide NZ_JAMYIY010000001.1 Lanthipeptides: NKE64_RS02785_lanthipeptide NZ_JAMYJP010000014.1 Lanthipeptides: NKE68_RS07350_lanthipeptide NZ_LR738722.1 Lanthipeptides: STREPSUIS_RS03955_lanthipeptide NZ_VZMP01000023.1 Lanthipeptides: F6P50_RS09295_lanthipeptide NZ_VZNS01000007.1 Lanthipeptides: F6P79_RS05700_lanthipeptide
Lanthipeptides: SSUD12_RS06540_lanthipeptide
3
G T G W F A T I T D D C P
15
G+G+ T+T D C P
2
G S G F V K T L T K D C P
14
21.2% NZ_AQQB01000068.1 and 6 others:
NZ_BCEY01000024.1 Lanthipeptides: GOZ53_RS05100_lanthipeptide NZ_BCEZ01000067.1 Lanthipeptides: GOZ55_RS11230_lanthipeptide NZ_BCFC01000053.1 Lanthipeptides: GOZ35_RS07920_lanthipeptide NZ_BCFG01000017.1 Lanthipeptides: GOZ50_RS03220_lanthipeptide NZ_BCFI01000009.1 Lanthipeptides: GOZ54_RS02495_lanthipeptide NZ_CP019557.1 Lanthipeptides: BZG42_RS05725_lanthipeptide
Lanthipeptides: K738_RS01000000110290_lanthipeptide
3
G T G W F A T I T D D C P
15
G+G T+T D C P
2
G S G L V K T L T K D C P
14
20.7% NZ_LMSL01000013.1: Lanthipeptides: allorf_11272_11457_lanthipeptide
3
G T G W F A T I T D D C P N S
17
G G W + T +C S
7
G C G W L C S Y T G E C G C S
21
20.6% NZ_FNYB01000007.1 and 1 other:
NZ_KB976303.1 Lanthipeptides: IGY_RS28100_lanthipeptide
Lanthipeptides: BMZ34_RS15340_lanthipeptide
3
G T G W F A T I T D D C P N
16
G G+ T+T D C P
2
G P G Y I E T L T K D C P R
15
20.6% NZ_JAESIP010000017.1 and 3 others:
NZ_LT907978.1 Lanthipeptides: EHLA_RS12685_lanthipeptide NZ_QRYY01000029.1 Lanthipeptides: DWW21_RS18370_lanthipeptide NZ_SPFW01000044.1 Lanthipeptides: FGQ81_RS16590_lanthipeptide
Lanthipeptides: JMK14_RS12260_lanthipeptide
5
G W F A T I T D D C P N S V F V C C
22
G T T +C P +C C
17
G R L C T G T A E C P I M T I I C C
34
20.0% NZ_CP051884.1 and 2 others:
NZ_CP051884.1 Lanthipeptides: HGK68_RS15125_lanthipeptide NZ_CP051884.1 Lanthipeptides: HGK68_RS15125_lanthipeptide
Lanthipeptides: HGK68_RS15125_lanthipeptide
5
G W F A T I T D D C
14
G W T I T +C
16
G W L C T I T H E C
25
17.5% NZ_CM001792.1 and 1 other:
NZ_CM001792.1 Lanthipeptides: C794_RS17980_lanthipeptide
Lanthipeptides: C794_RS17980_lanthipeptide
5
G W F A T I T D D C
14
G W F T I T +C
24
G W F C T I T K E C
33
16.7% NZ_CP011131.1 and 2 others:
NZ_CP090945.1 Lanthipeptides: L1A79_RS00960_lanthipeptide NZ_JAGGRJ010000002.1 Lanthipeptides: J7J53_RS00860_lanthipeptide
Lanthipeptides: LG3211_RS26005_lanthipeptide
3
G T G W F A T I T D D C
14
G G W + T +C
6
G C G W L C S F T G E C
17
16.7% NZ_JAJAGO010000028.1 and 1 other:
NZ_JAJAGO010000028.1 Lanthipeptides: LHJ74_RS33590_lanthipeptide
Lanthipeptides: LHJ74_RS33590_lanthipeptide
5
G W F A T I T D D C P
15
G W+ T+T +C
16
G W W C T L T K E C Q
26
14.6% NZ_FQZK01000006.1 and 2 others:
NZ_FQZK01000006.1 Lanthipeptides: BUE45_RS13060_lanthipeptide NZ_FQZK01000006.1 Lanthipeptides: BUE45_RS13060_lanthipeptide
Lanthipeptides: BUE45_RS13060_lanthipeptide
1
K R G T G W F A T I T D D C
14
+ T G F T+T +C
21
R N N T G R F C T V T V E C
34

#### Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine
Lanthipeptides
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists the number of lanthionine bridges, possible molecular weights, and the scores for cleavage site prediction and RODEO.

ctg1_159 - Class II
  Cleavage pHMM score: 4.40
  RODEO score: 0
  Monoisotopic mass: 2347.1 Da
  Molecular weight: 2348.7 Da
  Number of bridges: 3
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    2366.7 Da N = 1

gnlProkkaHDCEGNDM_3 - Region 1 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 12,295 - 24,391 nt. (total: 12,097 nt) Show pHMM detection rules used
Region on contig edge.
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
KnownClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
gnlProkkaHDCEGNDM_13 - Region 1 - T3PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 458,893 - 500,059 nt. (total: 41,167 nt) Show pHMM detection rules used
T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
KnownClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
gnlProkkaHDCEGNDM_21 - Region 1 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 116,469 - 135,260 nt. (total: 18,792 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
KnownClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.