LOCUS       c00022_gnlPro..        15752 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PPHPDNCN_22.
ACCESSION   c00022_gnlPro..
VERSION     c00022_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 23:08:19
            Original ID  :: gnl|Prokka|PPHPDNCN_22
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15752
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15752
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2635:5752]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2636..5752
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..15752
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15752
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             546..1061
                     /locus_tag="ctg22_1"
                     /transl_table=11
                     /translation="MLAWLPFFLISLMFIVLLYACARSARTNIQRFKQLSLIAFLWVLT
                     AFCYTPTSYNFGTQLVIQYIQWGPVKLNVIPFQQLDIEFWLNVLLTVPLGGLLAWNFPD
                     LPWRRFIWLGFLTGLTLELGQFILDWLVNLKRWVDIDDVITNWAGVIIGAAGYKIARHV
                     PGLRWLQK"
     CDS             complement(1229..2218)
                     /locus_tag="ctg22_2"
                     /transl_table=11
                     /translation="MRMLEQIEQYIDSCIEAGDIYGASFSLITPKGINQYYHGKQGRDE
                     FAVGLDPAMIYDLASVTKVVGTTTRIFQLLSDHTIHLTDSVARSLPGFTHPEITIKNLL
                     LHNSGLPADIDNLDKMQREDLIKAVYDAPLVTAPGTTYVYADLGFILLGWIIRAVDGSL
                     ARSIQDHVCYPLAMTNTGYNLNRPKIRFVPTEFDPRRGQIQGQVHDYKAFLLNGESGHA
                     GLFSTLTDLSVFIEMMLNFGEYQGKRVLDENVFDWLGEYDENGRTLGWERRAGRHQYFH
                     TGFTGPAVAFDLDRQIGLVVLTNRVYPTSDNQVWNQDRKRVFDLFFES"
     CDS             2636..4894
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_3"
                     /sec_met_domain="Gly_radical (E-value: 1.2e-39, bitscore:
                     126.9, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 1.9e-246, bitscore:
                     810.7, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MITSEKTTKPAAWKGFKGGHWQEEINIRDFIQNNFTQYNGDESFL
                     AGPTAATKTLNDKVLELKKQERAAGGVLDADTKVVATITSHGPGYIQKDLEKIVGLQTD
                     KPLKRAFMPFGGIRMADDALKSYGYTPDEENDKIFTEYRKTHNQGVFDVYTPDMRKARH
                     YKIITGLPDAYARGRLIPDLPRVAVYGIDRLMEDKANDFAHIGDGELTDDVIRLREEVQ
                     DQYRALADMKKMAASYGYDISKPATNAQEAIQWMYFAYLAAIKTQNGAAMSVGRIDTTM
                     DIFIQRDLDNGVLDESQAQELIDQFVMKLRMVRFIRTEEYNSLFSGDPIWATLSMCGLG
                     VDGQHHVTKTAFRILKTLDNMGAAPEPNITILWSDRLPEDFKRYATEVSIDSSTIQYEN
                     DDLMRVQWGTDYYGIACCVSAQPIADGIQYFGARANLAKAILYAINGGRDEIAGDQVGP
                     AYEPITSEYIDYDEFMKKLDKQMDWLADTYVNSLNAIHYMHDKYYYEAAQLALKNTDLD
                     RTFATGISGLSHAADSISAIKYGHVKVIRDERGIAVDFKADNDYPRYGNNDDRADDIAK
                     WLVKELYSKMNTHHLYRNAKLSTSVLTITSNVVYGKNTGTTPNGRQKGEPFSPGANPAY
                     GAEKSGALASLLSTAKLPYRYATDGISNTFGVTPNTLGHDLESRKDTLVNMLDGYMKND
                     GMHLNINVFNKDTLIDAQKHPEEYPTLTVRVSGYCVYFADLTKEQQDDVISRTFFESM"
     CDS             4931..5752
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 74.5;
                     E-value: 3.4e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_4"
                     /sec_met_domain="Radical_SAM (E-value: 2.7e-27, bitscore:
                     87.8, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKQVSTTQAAAKEPLIGYVHSIETFGSVDGPGIRYVAFLQGCR
                     MRCQYCHNPDTWKLNVGDQMTADEILEDAAKYRAFWGKTGGITVSGGESLVQIDFILDL
                     FEKAKAMNISTCLDTSGQPFTREQPFFDKFERLMKVTDISLVDIKHIDSAKHKQLTQYG
                     NENILDMIQYMAQHHDDMWIRHVLVPQRTDYDEDLKKLGDYIAKIPNDVVQKVEVLPYH
                     TLGVKKYHEMKIKYRLEGIESPTQDRVANAEKLLHTADYNGYKTWMPLPKL"
     CDS             5768..5953
                     /locus_tag="ctg22_5"
                     /transl_table=11
                     /translation="MTKTPAIQSSTDGCVTGVFLLARRMHVLLAGISTVARKKGAASLN
                     QQRLSLIMPYPMTVSP"
     CDS             complement(5977..6306)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FeS_assembly_P"
                     /gene_functions="other (smcogs) SMCOG1048:Iron-sulfur
                     cluster assembly protein (Score: 66.9; E-value: 4.7e-21)"
                     /gene_kind="other"
                     /locus_tag="ctg22_6"
                     /sec_met_domain="FeS_assembly_P (E-value: 3.7e-21,
                     bitscore: 66.9, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEGRDTMTTTFKDRAFEALGHVIDPELGIDLVNLGLIYDAQLTAE
                     GTAEITMTLTIAGCPLTEWLAKDIHDELIKLPEVNNIEIEIVWEPAWNESMMSREARME
                     LGIHS"
     CDS             7349..8269
                     /locus_tag="ctg22_7"
                     /transl_table=11
                     /translation="LKTINLGHSNIQASSVALGIMRMDALDVAQATKVIDTAVDLGINY
                     VDSADIYGGGQSSTIFGQALKQAHVSRDQLYIQSKGGIVPGKRYDFSKQHILAAVDGEL
                     QRLGVDYLDTFLLHRPDALMEPEEVAAAFDKLQTSGKVRHFGVSNFNPMQVDMLQAALN
                     QRLIINQLQFGIMHTGAIDFGLHTNMQDERSLNHDGEMIEYSRLHKMTIQAWSPYQYGN
                     FAGIFLDNPKFPELNNAMQALADEKQVTKSAIATAWILRHPAHFQVILGTMNPEHLAQN
                     AAGADVTLSRQEWYDIYFAAGNDLP"
     CDS             8439..8963
                     /locus_tag="ctg22_8"
                     /transl_table=11
                     /translation="MTSTCTICERIKLIQAHQNPYFVYELTTGYVVLADSQYFEGYTLF
                     LAKHHVTELHHLPAHEKLRYLEEMSIVQEACAQAFHADKMNIELLGNGDAHVHWHLFPR
                     HNGDTPNPGPVWWTPLETIYGDDVSLDIPRLSRLKRTLSVAIEATLNAREAELQALEAL
                     TRPASHRIDSN"
     CDS             complement(9058..9303)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GlcNAc_2-epim"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_9"
                     /sec_met_domain="GlcNAc_2-epim (E-value: 0.0001, bitscore:
                     13.3, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTAPLSSFEKNIPAVTELLAVDAELQTFFVALTPGYQREWARFI
                     FGTKAQATKERHIEVMKTVFRAGYKSKRAYDSRSDK"
     CDS             9476..9904
                     /locus_tag="ctg22_10"
                     /transl_table=11
                     /translation="MPKFDITLISPERAKAMLTEYKEQRKNSVPHLAHPGRYILPDYKL
                     TRRRAAFKIVKHTFLTPHYKSYVAMDSDNGHTLWFHNFGSLTEALFWLETGLKISDTDS
                     HSNYKEWMAKHTTEIETFKDLLREQKHKQGPKTKKKAK"
     CDS             complement(10007..10681)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lipase_GDSL_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_11"
                     /sec_met_domain="Lipase_GDSL_2 (E-value: 8.4e-20, bitscore:
                     63.5, seeds: 1564, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIAMIVKGGLAMAISNGHVSFKRPAWLGDSITANNGLATVHYHDI
                     LAADWDVERSDNLGISGSTIGSRYDAMAARYQAIPEDADFIAVFGGVNDYGRNQPLGQY
                     GDCDMTTFYGALMVLLTGLQTNWPTVPKLFISAIHIGSDFGGSFSAVTNGLGYRQSDYE
                     AAIAQMTADYGVPHLSLYRDAGMTFAIPAQAAIYSVDTLHPNNAGHRVIARKLQSFLDS
                     HF"
     CDS             complement(11664..13331)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BCCT"
                     /gene_functions="transport (smcogs)
                     SMCOG1001:betaine/carnitine/choline family transporter
                     (Score: 410.4; E-value: 2.8e-125)"
                     /gene_kind="transport"
                     /locus_tag="ctg22_12"
                     /sec_met_domain="BCCT (E-value: 2.2e-125, bitscore: 410.4,
                     seeds: 90, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSSRFIILKSKNIDWWVYLPTIGLFAAASVVLLMGGHSLETSLS
                     GILNWLTNNMSWLYMSVYVITFIFFIYLGFSKLGKTKLGDPDDKPEFSTYHWGSMVYAT
                     GIDASILMLSMVDPLRYLQSPSFGVKPFSTSAYNYAHMLGQFNWGPMAWMMFAPATIAI
                     AYAMYVKHIKVQRLSAAISVLQGPGKGKQIARNTIDFLVIIGIMGGVGTSVGMEIPVIS
                     KVLSAVTGIADTMTLKLGLFALLFVIFAMAVFNGLKKGIGRLSAAHVWLAIGFLIVVLI
                     VGPTLYILNSETNSIGLFVNKFITLSTNTAPNGHATAMQRQTIFYWGWWLSFMPVMGLF
                     IARISRGRTIRQVLGGMLLWGSLGCVSFYAILGGYALYLQRMGIVNLVHILNTQGQAAV
                     IAAVLSTLPLKMIMLALYCLSCFIFLATTVSSFAFITSSFTSKKLAAGEQPSRFNRMSW
                     VVIFLVFSLGLVTVGGFESIQSICAMSGFPLTIVALVLLYSIHHDLTTDPVKEAAKANA
                     KAAELARRKRLARDVEITTKTDYARERRTARKRETEAD"
ORIGIN
        1 agagttcgtt cgacttgcat gtattaggca cgccgccagc gttcgtcctg agccaggatc
       61 aaactctcaa attaatgatg agttctaaaa agctcattta atgttgtact aaaatttatt
      121 tgctagcaaa ttgacttcgc aaatgttttg ctcttgattc aaaaccaaga gaccctacac
      181 atttgattcg tcgaaacttt gttcagtttt caaagatcta attccgtgtg ttaatcgctt
      241 aacacaactt aatcatcata acatcttaat caatatcttg tcaacaactt tttttaagaa
      301 gcaacttgat taatttgtcg tggttgccat tgcgacaaca gaaactatct taccaattac
      361 tgaagaagtt gtcaacaact aattccaata attatttggt ggtgagatgt atctgccgta
      421 gcagcaacgt ttactaatat accaattgaa gtaaaaagtg tcaacacttt ttctgaattt
      481 ctttttatta atagtcaaac cagctttctt tctctatact atttaattaa aggagcgact
      541 aaattatgct agcttggcta ccattctttt tgatttcatt aatgtttatt gttctactat
      601 acgcttgtgc gcgatcagcg cgcacaaata tccagcgttt taagcaactc agtttaattg
      661 cctttctctg ggtcttaact gctttttgct acacacctac cagttacaat tttggtaccc
      721 aactcgttat tcaatatatt caatggggac ccgttaagct gaacgtgatt cctttccaac
      781 aacttgacat tgaattttgg ctcaacgttc tcctcactgt tccattgggc ggtttactgg
      841 catggaattt tcccgacttg ccctggcgtc gttttatttg gttgggattt cttacggggc
      901 taacactcga gctgggacaa ttcatccttg actggttggt taacctcaaa cgttgggttg
      961 atatcgatga tgtcatcaca aattgggctg gtgtcattat cggtgccgct ggttataaaa
     1021 ttgcacgtca tgttcccgga cttcgctggt tgcaaaaata acgtatatat agaagcaaaa
     1081 agcaaaatag cgtttgctta gcacccacaa gtgccaaaca cttcagcggt ctagctgtca
     1141 tgaaatcgta attaaataag cgtcgcagcc ttaagtggct gcgacgctta tttaatttaa
     1201 ctactaacta ttaatgaagc tgccatcatc aggattcaaa aaacagatcg aatactcgct
     1261 tacgatcttg gttccagacc tgattgtcac tagttggata aactcgattt gttaacacaa
     1321 ccagcccaat ttgacgatcc aaatcaaaag caactgccgg gccagtaaaa ccagtatgga
     1381 aatattgatg tcgtcccgca cgtcgttccc aacctaacgt ccggccattt tcgtcatact
     1441 cgcctaacca gtcaaagaca ttttcatcca gcacccgttt gccttgatat tcaccaaagt
     1501 ttaacatcat ttcaataaat acggataaat ccgtcagcgt tgagaacaag cctgcgtgac
     1561 cactctcacc attcaacaaa aaggctttat aatcatgcac ctgtccttga atctgacccc
     1621 gccgcggatc aaactccgtc ggcacaaacc gaatcttcgg acgatttaag ttataacccg
     1681 tattggtcat cgctagtgga tagcaaacgt ggtcttgaat actccgagcc aatgagccgt
     1741 caaccgcacg aataatccat cccaataaaa taaatcccag gtctgcatag acatacgttg
     1801 tccctggtgc cgtgacgagt ggcgcatcat aaaccgcttt gatcagatct tcacgttgca
     1861 tcttatccag gttatcaata tctgccggta gcccactatt atgaagtaac aagtttttaa
     1921 tcgttatttc aggatgagtg aacccaggta aagaccgggc aaccgagtcc gttaaatgaa
     1981 tcgtgtggtc cgataacaac tgaaaaatcc tcgtcgtggt ccctacaacc ttagttaccg
     2041 atgctaggtc ataaatcatc gcaggatcta agcccacggc aaactcatcg cggccctgct
     2101 taccatgata gtattgattg atacctttag gggtgatcaa gctaaacgac gccccataaa
     2161 tgtcgccagc ttcaatacaa ctgtcaatat attgttcaat ttgttcgagc atccgcatta
     2221 cgcccacctt tcactacatt cactagtttc tgcttatctt ctttatgata acgaacttcc
     2281 tcataaaatc aacggcaaac gcttttaaca ccctccacac ctcgttgcac tttttattaa
     2341 ttaactagtt aaacacttgt tacattatgg acaatattcc acttatatat caaaacaagt
     2401 cttgttttta gccgttttct aaatataatt aagtgaatta ccaatgccta tctagctatg
     2461 taagtactgt tatatcaacg ttaatagtca acttttcaat aatagattgc aaaaaaataa
     2521 cccaaacgtg aaataaatcg cctgaaagcg gttacaaatc cagcaaaaaa tgttatgatt
     2581 caaatataga attttatcaa tcatttgatt ggattcaaat tatggaggcg agaaaatgat
     2641 tacatcagaa aagacaacaa aaccagcagc ttggaaaggt ttcaaaggcg ggcactggca
     2701 ggaagaaatc aacattcgtg attttattca aaataacttc acacagtaca atggcgacga
     2761 aagcttcctg gccggaccaa cagccgctac taagaccttg aatgacaaag tcttagaatt
     2821 aaagaaacaa gaacgtgccg ctggtggtgt gttggatgct gatactaaag tcgttgcaac
     2881 gattacttca cacggccctg gttatattca aaaagatctc gaaaagattg ttggtctcca
     2941 gactgacaag cctttgaagc gggccttcat gccatttggt ggtattcgaa tggctgatga
     3001 cgctttgaaa tcatacggtt atacccctga tgaagaaaac gacaagattt tcactgaata
     3061 tcgcaagact cataaccaag gcgtcttcga tgtttatact cctgacatgc ggaaagcacg
     3121 tcactacaag atcatcaccg gactaccaga tgcatacgca cgtggccgtc tcattcctga
     3181 tcttccacgg gtcgctgttt atgggatcga tcgtttaatg gaagacaaag ctaatgactt
     3241 tgcccacatt ggtgatggtg aattgactga tgatgttatt cgcctccgtg aagaagttca
     3301 agatcaatac cgtgctttag cagatatgaa gaagatggct gccagttatg gctacgatat
     3361 tagcaagcct gcaactaatg ctcaagaagc tattcaatgg atgtacttcg cttacttagc
     3421 tgctatcaag acccaaaacg gcgctgcaat gtccgttggc cggattgata caacgatgga
     3481 catcttcatc caacgtgact tggacaatgg tgttctggac gaaagccaag ctcaagaatt
     3541 aattgatcaa ttcgtcatga aactacggat ggttcggttc atccgtactg aagaatacaa
     3601 ttctctcttc tctggtgacc caatctgggc aaccttatca atgtgtggtt taggcgtcga
     3661 cggtcaacac catgtgacta agaccgcttt ccggatttta aagactttgg acaacatggg
     3721 cgccgcacca gaaccaaaca tcacgatttt atggtcagac cgcttaccag aagacttcaa
     3781 acgttacgca actgaagttt caatcgacag ttcaaccatt cagtatgaaa atgatgactt
     3841 gatgcgggta caatggggta ccgattatta tggcattgct tgctgtgttt ccgcacaacc
     3901 aattgctgat ggaatccagt acttcggtgc ccgggcaaac ttagccaaag cgattcttta
     3961 tgccatcaat ggtggccgcg acgaaattgc tggagatcaa gttggccctg cttacgaacc
     4021 aattacttca gaatacatcg attacgacga attcatgaag aaattagaca agcaaatgga
     4081 ttggttagct gacacttacg ttaactcact gaatgcaatt cattatatgc atgataagta
     4141 ctactatgaa gctgcccaat tagctttgaa gaatactgat cttgatcgga cctttgcaac
     4201 tgggatttct ggcttatcac atgccgcgga ttcaatctca gctatcaagt atggtcacgt
     4261 taaagtaatt cgtgacgaac gtggtatcgc cgttgacttc aaagccgaca atgactaccc
     4321 acgttatggg aacaatgacg atcgcgctga tgacattgct aaatggttag tcaaagaatt
     4381 atacagcaag atgaacacgc atcacctcta tcggaatgcc aaactttcaa cttctgtttt
     4441 gacgattacc tccaacgttg tttatggtaa gaacactggt accacaccaa atggccgtca
     4501 aaaaggcgaa ccattctcac caggtgctaa ccctgcatac ggtgctgaaa agagtggtgc
     4561 attagcttca cttctttcaa ctgccaaatt accataccgt tacgcaactg acgggatttc
     4621 caacacgttc ggcgttactc ctaacacgtt aggccatgac ctcgaatcac ggaaagacac
     4681 gttagtaaac atgttagacg gttacatgaa gaacgatggg atgcacttga acatcaacgt
     4741 cttcaataaa gacactttga ttgatgctca gaaacaccct gaagaatacc caacattaac
     4801 ggttcgggtt tctggctact gtgtctactt cgcagattta accaaggaac aacaagatga
     4861 cgttatttca cggacattct tcgaatcaat gtaacattta atctttaata gttaagaagg
     4921 cgaaaggctc atggaaaaca aacaagtttc aacaacgcaa gcggcggcaa aggagccttt
     4981 gataggctac gttcactcca tcgaaacgtt tggctccgtt gacggaccag gtatccgtta
     5041 cgtggcattc cttcaaggat gccgcatgcg ttgccaatac tgtcacaacc ctgatacttg
     5101 gaaactcaac gttggcgatc aaatgacggc cgacgagatt ctcgaagacg cggctaaata
     5161 ccgggctttc tggggcaaga cgggtggcat cacagtcagt ggtggtgaat cactggtaca
     5221 aatcgacttc atcttagact tattcgaaaa agccaaggcg atgaatatca gtacttgtct
     5281 ggatacctct ggacagcctt ttacccgaga acaacctttc tttgacaagt tcgaacgtct
     5341 aatgaaggtc acggacattt cgttggtcga cattaagcac atcgattctg ccaaacacaa
     5401 gcagttgacc cagtatggga acgaaaatat cttggatatg attcagtaca tggcccaaca
     5461 ccacgatgat atgtggattc gtcacgtcct ggttccccaa cggactgatt acgatgaaga
     5521 cttgaagaaa ctcggcgatt acattgctaa gattccaaac gacgtcgttc aaaaagtcga
     5581 agtattgccg taccatactt tgggcgttaa aaaatatcat gaaatgaaga tcaagtaccg
     5641 gcttgaagga atcgagtctc caacccaaga tcgggtggca aatgccgaaa aactactgca
     5701 caccgctgat tacaacgggt acaagacatg gatgccattg ccaaaacttt aaatcggcat
     5761 ttctagcatg actaaaacac cagcgataca atcgtctacg gatggttgtg tcactggtgt
     5821 ttttttgctg gctcgacgca tgcacgtatt gctggctgga attagtacag tggcacgcaa
     5881 aaaaggcgcc gcaagcctaa accagcaacg tctttcctta atcatgccct atccaatgac
     5941 cgtcagccct tgaactagct gcgaacaggc cggccactaa ctatgaatgc ctagttccat
     6001 tcgagcttcg cgggacatca tactttcgtt ccaagcaggt tcccacacaa tctcaatctc
     6061 gatattgtta acttctggta atttgatcag ttcatcgtga atgtccttag ccaaccattc
     6121 ggtcaaagga cagcccgcaa tggtcaacgt catggtaatt tcagcggtcc cctccgccgt
     6181 caattgtgca tcatagatca accccaagtt aactagatca attcctaatt cagggtcaat
     6241 gacatgtcct agcgcctcga aggcccggtc tttaaacgtt gttgtcatcg tatctcgtcc
     6301 ttccatacca gcttgaattc actgattaat cacgccaacg tttcgcggta taagtgccac
     6361 cacacttgat acacgtcatc gttatataaa gcgctttctt gtctacttct attgtaccgt
     6421 atgtcagccc atattcaatc aattattagc gctaattagc cgacttttca aacgatcggt
     6481 caatcagcaa attatgcgac tatttctcga aaaaatttac tataatcccc gatatagcag
     6541 cgttttgagt cactattgat ttttattgcg aattcgcggt tgtttttgtt gtaagcgttt
     6601 gcggtttatg ctattatact aagtgaggaa aggaattaat cctcgattag caaagcttct
     6661 caaaagagtt tggctgtcgc tgtaatgtta gacagctagt atcacagttt gggtcgttat
     6721 cgaaaccgtt ttaagcgccg tgaagcgtta tcggtctagc gagtgtcgtg agatttacgt
     6781 tggatgactg aacgttgacc cttagataaa cgataaccgc aaagaattaa ttggcattag
     6841 aatgacgaac agattttaac taagttttag ttggaaacag gtgtctccga tgaccagttg
     6901 ttagttccac attaccagtt ccatttgtag actcaggtat tacaaagttt aaacggaggt
     6961 gcatgtctgt tacgaagaca ttcccaagtt ttaaacgcga gtttgacttt cgttaaaacc
     7021 cgtctaacga gtcgcaatca agtaacaacc ttactttaga tcgactatag cagatagtta
     7081 caataaatac gggttagtcc gttagaagtt ggacacgcgt aaaattgaat agcatgaagg
     7141 tgtatcatat taacactgaa caatttttca ttgctaatca ggattattcc tcataagtag
     7201 aactcaagta gagaagcctt gggttctatt ttttttgctc taaaatcaga tttaccaaca
     7261 gtcggcacca gtcgtaaccg tttacatcct cttacgaaaa ccgtatactg aatttaaatc
     7321 aagttgcaca ttgaggagga ctttagtttt gaaaacgatt aatttaggtc acagcaatat
     7381 tcaagcttcc agcgtggcgc ttggcatcat gcgcatggac gccttggatg tcgctcaagc
     7441 caccaaggtt atcgataccg ctgttgattt aggcatcaat tacgttgatt cagctgatat
     7501 ctacggtggt ggtcaatcat cgaccatctt cggtcaagca ctcaagcagg ctcacgtatc
     7561 gcgtgatcag ctctatattc agtcaaaagg cggcatcgtt cctggcaagc gttacgactt
     7621 ttccaaacag cacatactgg cagccgtgga tggcgaactt caacgcttag gtgttgatta
     7681 tctcgacacc ttcctcctcc atcgaccgga cgccctgatg gaacccgaag aagttgctgc
     7741 cgcttttgac aagttgcaaa ctagcggcaa ggtgcgccac tttggcgtct ctaacttcaa
     7801 tcccatgcaa gttgacatgc ttcaagcggc actaaaccaa cggctcatca tcaaccaact
     7861 ccaatttggt atcatgcata ccggtgcgat cgactttggc ttgcacacga acatgcagga
     7921 cgaacgtagt cttaaccacg acggcgagat gatcgaatac tcacggctcc ataagatgac
     7981 gattcaagct tggtcgcctt atcaatacgg taacttcgcg ggtatcttct tagacaatcc
     8041 gaagtttcca gaacttaata atgccatgca agcactcgcc gatgagaaac aggtcactaa
     8101 atcagctatt gcgaccgcat ggattctccg gcacccagcc cacttccaag tcatccttgg
     8161 tacgatgaat ccggaacatc tagctcaaaa tgctgctgga gcagacgtta cgctttctcg
     8221 gcaagaatgg tacgacattt actttgcagc aggcaacgat ttaccttaat cacgatcgac
     8281 ctaacagaat tgacgattag tttttacaat caaaacgacg accccaaatc aggattgatt
     8341 ttcaggtcgt cgttttttag acgtttcact aacatttttg atgtactcac cacatctacg
     8401 cgtatactta atcttatcaa gactcaggag gcgagcgaat gacatccact tgcacgatct
     8461 gtgaacgaat caaactaatt caggcacatc agaatcctta tttcgtttac gaactcacaa
     8521 cgggctacgt ggtccttgct gatagccagt actttgaagg ctacacgctc tttttagcca
     8581 aacatcacgt taccgaatta catcatttac cggcacacga gaagttacga taccttgagg
     8641 agatgagtat cgtccaggaa gcttgtgcgc aggcctttca tgcagacaaa atgaacattg
     8701 aactactcgg gaatggtgac gcgcatgttc attggcactt atttcctcgc cataacggtg
     8761 atacgcccaa ccccggtccc gtctggtgga caccgctgga aacaatttat ggtgatgatg
     8821 tcagtctaga cattccccgt ttaagccggt taaagcgcac gctcagcgta gcaattgagg
     8881 ccacgcttaa tgctcgggaa gcagaattgc aggctttaga ggcactcaca aggcctgcta
     8941 gccacagaat tgacagcaat tagaccaaat caggacccag acccgcttag atcttggtgg
     9001 ctacacccca attcttaatc gcaatccgtc accgtatttc aaattgccaa aatccaccta
     9061 tttatccgac cgactatcat acgctcgctt agatttatag ccagctcgaa aaaccgtctt
     9121 cataacttca atgtgccgtt ccttagttgc ttgtgcctta gttccaaaaa taaagcgggc
     9181 ccattcgcgc tgataaccag gtgtcaaagc cacaaagaac gtttgcaatt cagcatcaac
     9241 cgctaacaat tcggttaccg ccggaatatt tttttcaaat gaactgaggg gtgctgtact
     9301 cataatcaaa cctccgatta gttttactta aatttactgt aagaaaggga aaatccctaa
     9361 ttttcaggtt tttatatttc gaattttcat aaaattgcgc tatcattata gtataagtat
     9421 tattatttga ctactataat taaccatact gctattcacc aaggggagcc ctgctatgcc
     9481 aaaatttgat atcaccctca tcagtcccga acgcgctaaa gcgatgttga ctgaatataa
     9541 agaacaacgt aagaactctg tcccacatct ggcccatcct ggccgctata tcttgccgga
     9601 ttacaaatta actcgtcgcc gggccgcatt caaaattgtt aaacatacct ttttaacgcc
     9661 ccactacaag tcttacgttg ccatggactc tgacaacggc cacacactct ggtttcataa
     9721 tttcggttcc ctaaccgaag ctttattctg gttagaaacc ggccttaaaa tcagcgatac
     9781 cgactcccat tctaactaca aggaatggat ggctaagcac actacggaaa tcgaaacctt
     9841 caaagacttg ctgcgcgagc agaagcataa acaagggccc aagactaaga aaaaagccaa
     9901 gtagcccgtt ttgacaccta gattcagata agcagcagta cgcccattag cgtgctgctg
     9961 cttttattta cgatcaactg tgccattcat tactgactag gccaacctaa aagtggctat
    10021 ccaaaaacga ctgcagcttg cgtgcaatca cgcgatgacc ggcattgttc ggatgcaaag
    10081 tatccaccga ataaatggcc gcttgagcgg gaatcgcaaa cgtcattccc gcatcacggt
    10141 acaagctcaa atgtgggacg ccatagtccg cagtcatctg ggcaatcgct gcttcataat
    10201 ctgactgacg atacccgaga ccattagtca ccgcactaaa actgccgcca aaatcagagc
    10261 caatatgaat tgctgaaata aataacttcg gcacggtcgg ccaattcgtc tgtaatcccg
    10321 tcagtaacac cattaacgcg ccataaaatg tcgtcatatc gcaatcaccg tattgcccta
    10381 acggctgatt ccgaccatag tcattgacgc ccccaaagac agcaataaaa tcagcatctt
    10441 caggaatagc ttgatagcgc gccgccatcg catcgtagcg actcccaatc gttgaaccag
    10501 agattcccaa attatcgctc cgctcgacat cccaatcagc cgccaaaata tcatgataat
    10561 gcaccgtcgc caacccatta ttcgccgtaa tcgaatctcc caaccacgcc ggccgcttaa
    10621 aactaacatg cccattacta atcgccatag ccaatcctcc ctttactatc atcgctatca
    10681 ttctaatcca tcccacctga attatggtat aaagatgcct ttatttaaag tcaacagcca
    10741 ccagcttagg cccgctggaa acagttccgg ttagcgtaaa cctgcttagt tcgttcgtcc
    10801 tacgccgccc tccaggcatt tctgccaatt gctggaacgc ggtggacaca gatttaagcc
    10861 gaagaccacg tcttaaatac tggtcttcca ctaaccaagc caaggacgct tgctaagtgg
    10921 aatttcaccg ctgagcattg gccgaaacgc cttccagtcg ggacagtatt cgaatggcgg
    10981 acgaagatgt acccaacttt tgatgaattt gtcattgttc tccataaaca gtaattttgt
    11041 taatcaactg ttaggtcgaa aagatattgg gatagctcgc tatttcggaa ttactatagt
    11101 aataatagaa cacctcaaca aagtggttag ggtaacccta acgtctcgtt taaagttcct
    11161 gtatcaaaat aaccaacgac caattgtgcc gagttaagtg gccgttcatc agccattcga
    11221 gcggcttcct gaaacgtgtt cggtgccact aaagtctgtg cttgctatgc caacggacaa
    11281 atgcccaaac cgcattaatc cgttggctag acaatgctcg gcttcaaccc gtggcttgag
    11341 actggagggg ctgggtgaca atgctcagta gccaaattat tcttagtcgg aagtgatttc
    11401 cttccggctt agaataagac tcgtatttga gatgacgcgg gttattcgtt agctcaaatc
    11461 gatgtcggct gcgttccagc aattgtcacc cagccccgga ggtcggaata ggacgctcac
    11521 tggctgacga acagaaaacc aaccctaaaa ggcatctttc taccattatt tcaaacaggt
    11581 gggccaagct taaaaggctc gtattatgga aatccataat acgagcctag tttaattgat
    11641 atatttagtt caactgagta gcgctaatcg gcttccgttt cacgtttccg tgcagtacgc
    11701 cgttcgcgtg cgtagtcagt tttagttgtg atttcaacgt cacgtgctag ccgtttccgg
    11761 cgtgctaatt cagctgcttt ggcattggct ttcgcagctt ccttgactgg atcagtcgtt
    11821 aagtcgtgat ggatcgagta cagtaagacg agcgcgacaa tcgttaatgg gaagccagac
    11881 atcgcacaga tggactgaat cgattcaaag ccaccgaccg tgacaagccc caatgagaag
    11941 actaggaaga taacgaccca gctcatccga ttgaaacgac ttggttgttc ccccgcggcc
    12001 aactttttac tagtaaatga cgaggtaatg aaggcaaatg aagataccgt cgttgctaag
    12061 aaaataaagc aagataggca gtacaaagcc agcataatca tcttcaatgg taaggtcgac
    12121 aatactgctg caatcacagc ggcttgtcct tgcgtattta agatatgaac taagttaacg
    12181 atgcccatcc gttgcaagta taaggcataa ccacccaaga tggcgtagaa actgacacaa
    12241 cctaatgagc cccatagcaa cataccaccg agtacctgac gaatcgtccg gccccgagaa
    12301 atccgggcaa tgaataagcc catgactggc ataaaggata accaccagcc ccagtagaag
    12361 atcgtctgcc gttgcatggc cgttgcgtga ccatttggtg cagtattcgt gctcaacgta
    12421 ataaacttat tgacaaacaa gccaatacta ttagtttccg agtttaaaat atacaaagtt
    12481 gggccaacaa ttaaaacaac gattaggaag ccaatcgcta accaaacatg ggcagcactt
    12541 agccgaccga ttcccttctt caagccatta aaaacagcca tggcgaaaat tacgaataat
    12601 aaggcaaata accctaactt taaagtcatc gtatcggcaa tcccggtaac ggcactcaaa
    12661 acttttgaaa tgacggggat ttccatcccg actgaagtac caacaccacc cataatccca
    12721 ataataacga gaaaatcaat cgtgttccgg gcaatttgct tacccttacc aggaccttgt
    12781 agtactgaaa ttgcggcact gagccgctga accttgatgt gtttaacata cattgcatag
    12841 gcaattgcaa tcgtggctgg cgcaaacatc atccacgcca ttggtcccca attaaattgt
    12901 cccagcatgt gcgcataatt atatgcagaa gttgaaaacg gcttgacgcc gaatgaaggg
    12961 ctttggaggt accgtaacgg gtcaaccatg ctcaacatta aaatgctggc atcgatcccg
    13021 gtcgcgtaaa ccatactgcc ccagtgatac gttgaaaatt ctggtttgtc atcaggatca
    13081 ccaagtttgg ttttccctaa cttactaaac cctaagtaaa tgaaaaagat aaaagtgatc
    13141 acatataccg acatataaag ccagctcatg ttatttgtga gccagttcaa gatgccactt
    13201 aaactcgtct ccagcgaatg gccccccatt aataaaacaa cggaagccgc cgcaaagagc
    13261 ccaattgttg gtaaatagac ccaccaatca atattcttac tttttaaaat aataaacctg
    13321 ctactgagca tatactctct atatttagat caaattcgtg gttcttccta ccagcaatgg
    13381 tagtccccac gcgtaaattt ccgactagca atcggtacac ccctccgagt taatcctcgg
    13441 agcactcagc accctgactg tatcaggttt gaccggcatt gtcatccgca ttctgtttgt
    13501 gctaactcaa aatcagtagc agaatttcct tctttccgtt ggttgaatcc ggacaacgcc
    13561 atactgacaa atgattttta attgcttaat cgacgttggt gttcatcttg tttagctagt
    13621 gtttctatta ccatcgtgcc tttagcacac gaccgtcgtc acaccacgta acgattaatg
    13681 gttacactgc tcttgctaat agataacccc cttgaatcac cagataagcc caccgcacaa
    13741 ctgttagatt aattgcttgg tgcaccaaaa aagcgcttag taccgggtaa caagttacca
    13801 cctgcacagc gcacgttggc ttatacaaat gctgatttca gtattttctg atatctgatg
    13861 ttcgtttata agtatactag tattaaatca gaagtaaaat caatcatttt gagccgtcga
    13921 ggcctaaccc gtcaaggatt agacgagttt tacacccata ttttttctga aactttttaa
    13981 aagttttcgt aataattagt ttttagttta gaatcattct tatctgtttc aattaaaccg
    14041 atttcatgtt attcttgtaa caagtaaaaa aacgttatca tctaaaagga ggggaactgc
    14101 atgcggcact actataaatt aattttaacg gtcagcgtcg gtatcattgc ggttatttta
    14161 cagtttggtt tgcactacca attggcagca caaatcatca ttacattaat ggggtcactt
    14221 atggccttat caatgttagt tgagatgatc aaaaccttac gttcaggtaa gtacggggtt
    14281 gatttattag caattacggc gattgtggca acactagctg tcggcgaata ttgggctagc
    14341 cttgtcgttc taattatgct cactgggggt gactcgttag aagattatgc ggccaaacga
    14401 gcgaataccg aattgaaagc cttgctcgat aattcaccac gtattgccca ccgctcagtc
    14461 gccggccaat taacagatat tgccgttgaa gatgtccaaa ttggtgatca gctagtcgtc
    14521 aaacctggtg agctagttcc agtagacggt caccttattc aaggaacggc actctttgat
    14581 gaatcttcat tgacgggtga atctaaacca gtcgacaagc acgttggcga tgacattatg
    14641 tctggtgcgg tcaacggcga tagtgccgtt acaatggttg ttgataaatt agccattgat
    14701 agtcaatacc aacagttagt caaattggtt aaagaatccg aatcacgacc agccaaattc
    14761 gtacggctgg ccgatcgcta tgcagtccca ttcaccttgg tagcatacgt cattgccgga
    14821 gtagcttggg cattcagcgg tgatccccac cgatttgcag aagtcctcgt agtggcttca
    14881 ccttgcccgc tgattctcgc cgcacccgtt gcactcgtct cagggatgag ccgaactagt
    14941 cggaacggaa tcgtggtcaa gactggggac atgttggaga agttatctac ggctaagtcc
    15001 gccgcgtttg ataagacggg gaccattacc agtggtcaat taacagtcaa ccaaattgtt
    15061 cctcagcctg gttttactgc cgaacaaatc ttgcacctcg cagcgagcgc tgaacaaaac
    15121 tcaagtcata tcctggcccg ctcactcgtc aagtatgcga gtgccactag cctcagcccg
    15181 gcaacacaat tagcagaagt aacgggtaat ggggtcacgg caacgattga gcagcaacag
    15241 gtcaaagtgg gcaaacttaa attcgtcgca ccgactacaa ccgccaagcc acttgctact
    15301 actgctatct acgtcggcat cgatgaccag tacgcgggtt acatcacgtt tatcgacaat
    15361 gtccgccccg aagcagccgc cacgcttcaa gcactccacg ctgagggcgt tcaaaacgtc
    15421 atgatgctta ctggtgacca acaggcaatt gctgatcata ttgccgccga tgtcggtatc
    15481 gataccgttg ctgccgacct cctacccgca gataagattg cccacttaaa ggctgtacca
    15541 gcggccgaac gccccgttat catggttggt gatggtgtta atgacgcgcc ttccttggct
    15601 gttgctgacg tcggcattgc catgggcgcc catggctcaa ctgctgctag tgaatcggcc
    15661 gacgtcgtca tcttaaaaga cgatctcagt cgcgtggtca cggcggtgcg cattgctaaa
    15721 gataccatgc aagtggctaa acaagccgtt tg
//
