LOCUS       gnlProkkaAGLPHDGH_2    16028 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AGLPHDGH_2.
ACCESSION   gnlProkkaAGLPHDGH_2
VERSION     gnlProkkaAGLPHDGH_2
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 23:56:52
            Original ID  :: gnl|Prokka|AGLPHDGH_2
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 3135
            Orig. end    :: 19163
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16028
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[5000:11028]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..11028
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..16028
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..16028
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             215..1393
                     /NRPS_PKS="Domain: Aminotran_1_2 (32-385). E-value:
                     1.9e-71. Score: 232.9. Matches aSDomain:
                     nrpspksdomains_ctg2_5_Aminotran_1_2.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:aminotransferase (Score: 274.2; E-value:
                     2.9e-83)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_5"
                     /sec_met_domain="Aminotran_1_2 (E-value: 6e-71, bitscore:
                     233.1, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEFEKSEILKNLPKQFFANLVIKVNKKIAEGVDVINLGQGNPDKQ
                     TPEYIVKSTQKWVASPQSHKYSLFRGQSDFKQAVADFYQEKYQTTFDPEKEVAVLGGSK
                     TGLVELPLALMNPGDVFLLPDPGYPDYWSGATLGQVTFEKVPLLKENNFLPDLKSIPEE
                     LAKKAKFFYINYPNNPTGATATREFYEELVAWAKKYEVGIISDFAYGAIGFDGERPLSF
                     MEIPGAKDVGIEFYTFSKTFNMAGWRVAFAVGNADIIDALNLIQDHLFVSIFPALQYAG
                     IDALKAPERDSEINKIVDRYETRRNAFIQAAEKIGWKAFVPKGTFYAWMEVPKGYSSEE
                     FADLLLNEAGVAVAPGNGFGEYGEGYVRIGLLIEPERLEEAVDRIAKLNLFK"
     aSDomain        311..1369
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg2_5_Aminotran_1_2.1"
                     /evalue="1.90E-71"
                     /label="ctg2_5_Aminotran_1_2.1"
                     /locus_tag="ctg2_5"
                     /protein_end="385"
                     /protein_start="32"
                     /score="232.9"
                     /tool="antismash"
                     /translation="DVINLGQGNPDKQTPEYIVKSTQKWVASPQSHKYSLFRGQSDFKQ
                     AVADFYQEKYQTTFDPEKEVAVLGGSKTGLVELPLALMNPGDVFLLPDPGYPDYWSGAT
                     LGQVTFEKVPLLKENNFLPDLKSIPEELAKKAKFFYINYPNNPTGATATREFYEELVAW
                     AKKYEVGIISDFAYGAIGFDGERPLSFMEIPGAKDVGIEFYTFSKTFNMAGWRVAFAVG
                     NADIIDALNLIQDHLFVSIFPALQYAGIDALKAPERDSEINKIVDRYETRRNAFIQAAE
                     KIGWKAFVPKGTFYAWMEVPKGYSSEEFADLLLNEAGVAVAPGNGFGEYGEGYVRIGLL
                     IEPERLEEAVDRI"
     CDS             1561..1827
                     /locus_tag="ctg2_6"
                     /transl_table=11
                     /translation="MDHLVIKAIIWIFFIISAILEVNYKKKYGELDKRARKQVTLGTFL
                     IVTTIFDEGYENKILYIIVLIALLVYVVLVIYRLVMAIKDRKK"
     CDS             1848..2189
                     /locus_tag="ctg2_7"
                     /transl_table=11
                     /translation="MKAIYRGRKVDVWQVSRDNVQPDWVKYAFEHNGLRWLHGSGNKVR
                     IYWPAVTRAKKGIIRTILNGISASFVGIAGGSVSMYDIGFEGDVIDFTNSKVVTAEKFA
                     KKYRIVSEE"
     CDS             complement(2385..3359)
                     /locus_tag="ctg2_8"
                     /transl_table=11
                     /translation="MRYIKFTLLIYSFLLTWGITTNSISADEVTPTTTSETTVTPQSQS
                     TPVDSNDEDAAIEEKFYSHDVTIDEYNENVANFNKVNTDTVKNMVTENSNNLDQVLYIG
                     RPTCYFCRQASPHLRDFNQLINNQLYYYDIDAEPNAHDFAFKEIGIPGTPTTMRLKNGK
                     VISAWIGGEKTGQEFYDFLFSADANKLADSYTIKKTVSTDTSNPVITNNQNIEPTVKPI
                     PTNISQLKEEKTTTELVNTTSQPFKPVKKIQNPATTTNKKNKNSVLPQLGVVPLYHQPL
                     FKLPIPKIPKQLERTIMLITFLVLYLGFLICLWLSWKEINKRK"
     CDS             3584..3901
                     /locus_tag="ctg2_9"
                     /transl_table=11
                     /translation="MKAIFKGKEVQVWQISKTAEQPEWIKEAFKANYLKWSGDKLLFIM
                     NGVKAPVKISAWTNFKTLFNGASGWWATYASGYIGDYLDFTNRKIIPERKFKKKYKIVN
                     K"
     CDS             complement(3940..4203)
                     /locus_tag="ctg2_10"
                     /transl_table=11
                     /translation="MNSFSNNINFSKISVSLITLLLLIWTLVDGNLIHLGILAFSSLVT
                     TMLHFHYFESTDDKHPLNRIDFVLQLLFIFISIIKFFLISGR"
     CDS             4435..4608
                     /locus_tag="ctg2_11"
                     /transl_table=11
                     /translation="MNNNFVQVDKKELAHIIGGRNSYDYIDSGQFGYDIGCTIANTKFF
                     KRLRHSNQNICS"
     CDS             4738..4995
                     /locus_tag="ctg2_12"
                     /transl_table=11
                     /translation="MLKKLWETWLDGGFIRGKKRYVIAPVIWALLIPLGIWLFGNEGMS
                     YLDYIQTPKMIIVTIFCLIGGSTLLYLLDTAMKVNKHMKG"
     CDS             5001..5195
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_13"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 2e-16, bitscore:
                     53.8, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMKEFTVLTECELAKVDGGKRGPNCVGNFLGGLFAGAAAGVPLGP
                     AGIVGGANLGMVGGALTCL"
     CDS             5213..5419
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_14"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 4.1e-11,
                     bitscore: 36.8, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNLDKRFTIMTEDNLASVNGGKNGYGGSGNRWVHCGAGIVGGAL
                     IGAIGGPWSAVAGGISGGFASCH"
     CDS             5556..5651
                     /locus_tag="ctg2_15"
                     /transl_table=11
                     /translation="MIFWVTVIVAYSIFISIYTSKKEDGHLIKEF"
     CDS             5837..5956
                     /locus_tag="ctg2_16"
                     /transl_table=11
                     /translation="MKFEVLTEKKLQVIVGGTTKNWGKSQYKKCLFNFFGTCK"
     CDS             5956..7245
                     /locus_tag="ctg2_17"
                     /transl_table=11
                     /translation="MMSLNSEVDYFISVISLFLGIIFDYVFFYLISPIKKNIKKDSIFI
                     CTTFPLVFIFSGAGDRMAFYTELVEVTLFYFVYKRRIIDYGILGRLLLIQSYSYITYGV
                     ENLFFQLIGKQDTSINSMICGFIFVLIEYILFTKTTVVENLDNEYGKVYFFLILYLYFG
                     SIAVYYLANYVIKIDILAYTIAIIIIIGQLIFSLYIYNSSKKIRQDKLSLQQIKDLKTY
                     TQQLESSQRSLRKFKHDYQNMLLSLKLSAEKNHDKELIDKLAEYSSKILEDKVLWQFND
                     VDNIKDELLKSLFISKLNRIFQDNIQYSFECRDVIDSLSNKYNAFDIIRILGITYDNAI
                     EESLELGDEARIDTMVYRENGELEIEIKNRCRNTDLTIQDMRKSGFTTKKNHDGLGLAN
                     IEELSQPYNDIFINYQIKDGWFTFLMVMSI"
     CDS             7259..8053
                     /locus_tag="ctg2_18"
                     /transl_table=11
                     /translation="MEEYGIIICDDEKDQVRRIHDLVKYAIWSLEDSADSKDKEFKITL
                     EANSYIEVADYLEDNKVDSGVYFLDIELSRDRADKDGIDLAEFIRQRDPNAQIIFITAY
                     ENLAAMTYRRRTGALDFITKNDSDEVIQKRLNETLSLAARRIRESHAIKKMTFSYKMGR
                     RIINENINDILYIITTPKSHRLKIVTVNGMGEFTGDIKKLEVENDFLEKISQSCLANPS
                     NIVEINLSTRVISFKDGYKETFPRRSKAKMKSLIERYNLKTV"
     CDS             8090..8329
                     /locus_tag="ctg2_19"
                     /transl_table=11
                     /translation="MVEIGIIILLIVGFMVISRLKVNFTRNSKYTGFLLLILLNLNGLM
                     RTPMLTVKGLVLLGTLMIFVVMLIKEIKQNRIYS"
     CDS             8869..11028
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 315.2; E-value:
                     1.4e-95)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_20"
                     /sec_met_domain="Peptidase_C39 (E-value: 2.6e-43, bitscore:
                     140.7, seeds: 36, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR01193 (E-value: 0.0, bitscore: 1078.7,
                     seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHKYKKYYIPQVDESDCGVASLAMILKHYGSSLSLAYLRNIAKT
                     TMEGTTALGLVKTAQALGMETQAVKADMSLFEMKDITYPFIVHVVKEETLLHYYVVLKA
                     TPRYILIADPAPDVGITKMSYERFEKEWTGITLFIVLGIEYKPTKETRQSLISLFSKLF
                     KQKQLIVNIVLAALLITIISILGSYFLQGIIDTYIPNGMHSTLAIITLGLLVIYVFNSI
                     FTYARDFLLAILGQRLSIEIILSYIRHIFELPMEFFATRKTGEIVSRFNDASKIIDALA
                     STVVSIFLDVSIVVIMGIILAIQNLKLLGITLISLPIYTIIILTFTKAFERLNNKQMES
                     NAILSSSIIEDIQGIETIKALNSEQMRYRKIDSQFVDYLRKSLAYIKTDSLQQALKLFI
                     QQTLNVTVLWLGANLVISNQLSIGQLMTFNALLSYFVNPLQNIINLQPKLQSARVAHNR
                     LNEVYLVESEFKDRKAVHDVTQLQGNIIVQDVDYRYGYGENVLDKVNLTLKQGEKLTIV
                     GMSGSGKSTLVKLLVNFFAPVSGSIKLNNHDINNIDKHTLRSYINYIPQNPYIFAGTIE
                     DNLRLGNRSNVTDEDILMACKIAMIDTDIAKMPLQLKTELDENANILSGGQKQRITIAR
                     ALLSPAQVLIFDESTSGLDAITEKKLIDNLMKLKSKTIIFIAHRLSIAKRTNNILVLDS
                     GKIVEKGRHDELLAKKGYYYNLVNS"
     CDS             11045..12199
                     /gene_functions="transport (smcogs) SMCOG1029:RND family
                     efflux transporter MFP subunit (Score: 58; E-value:
                     1.3e-17)"
                     /gene_kind="transport"
                     /locus_tag="ctg2_21"
                     /transl_table=11
                     /translation="MEDKFLESSEFYSARFRNFSTMIIIPFTILLLAVVIFSFFGKKEI
                     TIQGAGTLEALGNNPVIQSTVNSPIEKNYLKEGKYVKKGDTLLVYNNVSIQDKGKLYNS
                     QKEILDRQLAALNLLKQGVQDNHDSFGEDDEFGYRNDLKSYLQQRNTYLTENTMIQDKS
                     KNDKAKQSSINNELKKQGASSTSIAEFDSSKYNIEINNQKMSDLQSSKLSSIDQEIIKI
                     KQNISELNANIDENNNTNREYKVKAVRDGILHINDEYSESHYISAGANLAQILPILKNQ
                     KTLKIKAYISTADISSIKVGQKVRFKVTRNVPKPIILTGKIYKISISPVEIGKENYYQI
                     EAKTDIQNTNRDLLKYGMQGQMVVITGKTTFFEYYKNKLFNIKQ"
     CDS             12300..13142
                     /locus_tag="ctg2_22"
                     /transl_table=11
                     /translation="MEEKFLNYDIPNFVKESPNYLKLFEKERIILKNKHDKWGIYFSEE
                     LGHPLEYKENSGKVDYIYDSFFEAYSQADNDGEVWFSDEIAHEVFGEPEDEDFNEKGEF
                     GSLSDDFFWTKNHLIFRHHGDYNVKNLENEYQEWKNLDKKVKEDSFTHENFLLIYEWLR
                     THPNFWKENVHGDRVFWETSHMNLNFMDIYPTSSETNGKVEWWAEGGYHVLDDTDVPYA
                     TTYYHDIALDCGGNTYEQAVLNFAKNIWLQTHGMLKDKEAKRDAIFERWAKDSGCESD"
     CDS             complement(13249..13515)
                     /locus_tag="ctg2_23"
                     /transl_table=11
                     /translation="MKKYLLFILSIVVALLTWIPNTRLFLTDSNIGTILILVLAIFVCV
                     FSVIYNKHSHSLWYIFSFILGLSPILFLIFVGIFLALGMPFAP"
     CDS             complement(13551..14372)
                     /locus_tag="ctg2_24"
                     /transl_table=11
                     /translation="MEYPYREKFLSWAKDVKHYRESTVMLYDYTVNSFYNYFYSQSEHG
                     NDIRLVRPQDITNYLVNIQEQHHIVANTANKYYFHLKKYFTFLYSNHLIDEYPLIDLKT
                     YKVNKYTNITLGWQQYLPEIFKIAELSDDAKLELFLISQNIEPKGLLNITFGQLRNFDT
                     ENTEILLDNIEIKPDNYFVFSLKNDPEKPLNSLNSLLMRVRPDEEILNMTLAPSKLRQS
                     YIYNYLLTNKDKSEIELLDHLHLSIKSLVYYRQNLLNIDFNNFVYETPKEK"
ORIGIN
        1 ctaatgcgta aacgtgttag ttaagtgggt gttgtcaacc acccaatgat gtagccacat
       61 atagtgtggg agcaacaaag ttgcgttatt accactgacc gtaaggtcgt gagttacaag
      121 cctcagtctt tagactgggg cagttgactc aacaaattca tgtatttgaa gatcgtagac
      181 cagaattata cgactaagag agcgaggaaa gacgatggaa tttgagaaat ccgaaattct
      241 aaagaatcta ccaaagcaat tctttgctaa tttggtaatc aaagttaaca aaaaaattgc
      301 agaaggagta gatgttatca atctaggaca aggtaatcct gataaacaaa ctcctgaata
      361 tatcgtcaag agcacacaaa aatgggtagc tagtccgcaa agtcacaagt actcattgtt
      421 tcgtgggcag tcagatttta aacaagctgt ggcagatttc tatcaagaaa agtatcaaac
      481 tacatttgat ccagaaaaag aagttgcagt tcttgggggc tctaaaactg gcttagtcga
      541 actaccacta gcattgatga atcctggtga tgtattttta ttacctgatc ctggttatcc
      601 agattattgg tctggagcta cacttggaca ggttactttt gagaaagttc cgcttttgaa
      661 ggagaataat ttcttaccag atttgaaatc tattccagaa gaacttgcta aaaaagctaa
      721 attcttctat attaactacc ctaataatcc aacgggtgcg accgcaactc gagaatttta
      781 cgaagaatta gttgcttggg caaagaaata tgaagtaggc atcatcagcg attttgctta
      841 tggtgcaatt ggttttgatg gagagcgacc actaagtttt atggagattc cgggagctaa
      901 ggatgttggt atcgaatttt ataccttctc taagactttt aatatggcag gttggcgagt
      961 tgcttttgcg gtaggaaatg ctgatatcat cgatgcttta aatcttatcc aagatcattt
     1021 atttgtaagt atctttccag ctctacaata tgcaggaatt gatgctttga aagctccaga
     1081 acgcgattcc gagatcaata agattgtaga tcgttacgaa actagaagaa atgcgttcat
     1141 ccaagctgct gaaaaaatcg gatggaaagc ttttgtacct aagggaactt tctacgcttg
     1201 gatggaagta ccaaagggat atagtagtga agaatttgca gatttacttt tgaatgaagc
     1261 tggagtagca gtagctcctg ggaatggttt tggcgaatat ggagaaggtt atgtacgaat
     1321 tggtttgtta attgaaccag aacgcttaga agaagcagtt gatagaattg caaaacttaa
     1381 tttatttaaa tagttgggaa tagtggcaag acagcgatgt ttttgtcgct atttttttaa
     1441 acgtacatgg atgtgttgtt aaccaaataa gcagaaaaaa gtgttaatta agaaaataca
     1501 gaattaaatt taattaaaat agtataataa tggcaaaaat agagaatagg tggtggaatg
     1561 atggatcatt tagttattaa ggcaattatt tggatatttt ttataatatc agcaattttg
     1621 gaagttaatt ataagaaaaa atatggtgaa ttagataaac gagctagaaa gcaagtaaca
     1681 ttaggaacat ttctaatagt aactacaata tttgatgaag gttatgagaa taaaatacta
     1741 tatataatag tattaatagc actgttggta tatgtagtat tagtgatata tagattagtt
     1801 atggctatta aggataggaa aaagtaataa gaaaggtgat aaagcaaatg aaagcaattt
     1861 atagaggtag aaaagtagat gtttggcaag tgagtagaga taatgtccag cctgattggg
     1921 ttaaatatgc ttttgagcat aatggattgc gatggctaca tggtagtggt aataaagtca
     1981 gaatttattg gccagcagtt actagagcaa aaaaaggaat aatacgaact attttgaatg
     2041 gtatttcagc ttcttttgtt ggtatagcag gtggtagcgt gtcgatgtat gatattggct
     2101 ttgagggaga tgttattgat tttaccaatt ctaaggttgt tacagccgaa aagttcgcta
     2161 agaaatatcg gatagtgtct gaagagtaaa cggcacatca tctgaagtta gcctcaaaaa
     2221 ataatatgag aaataaaatt gcaaattttg aaaaaagttg aatataaaga taggaccaat
     2281 ttactaattt atgcaaaaat taatgttttg acttagaaaa atcaattatt tgcataaatt
     2341 ttctaattgg tcctgttgct atatcgcata ttttacgttt ttatctattt ccttttattt
     2401 atttctttcc aactcaacca taaacatatt aagaatccca aatatagaac tagaaaagta
     2461 attaacatta tagtacgttc taattgctta ggaattttag gaataggaag tttaaataat
     2521 ggctgatgat aaagagggac aacccctaat tgtggtagaa cagaattttt gtttttctta
     2581 ttagtagttg tagctggatt ctgaattttt ttaacaggtt taaatggttg tgaagtagta
     2641 ttaaccaatt cagtagtagt tttttcctct ttaagttggc ttatatttgt tggtataggc
     2701 ttaacagttg gttcgatatt ttgattattt gtaataacag gatttgaagt atctgtgctt
     2761 acagttttct ttatggtata ggaatctgct aacttgttag catctgcaga aaataaaaag
     2821 tcataaaatt cttgtcctgt tttttcgcca ccaatccaag cactaataac cttaccattc
     2881 ttcaaacgca tagttgtagg tgttccagga attccaattt ctttaaacgc aaaatcatga
     2941 gcattaggtt cagcatcaat atcatagtag taaagctgat tatttattag ttgattaaaa
     3001 tcacgtaggt gtggtgaagc ttgacgacaa aaatagcaag taggacgccc aatgtagaga
     3061 acctggtcta aattgttgct attttcagta accatatttt taacagtatc agtattaact
     3121 ttattgaagt tcgctacatt ttcattatat tcgtcgattg taacatcatg agagtaaaat
     3181 ttttcttcaa ttgcagcatc ttcatcatta gaatcaacag gtgtactttg actttgaggc
     3241 gtaactgttg tttcggaagt tgtagtaggt gtaacttcat ccgctgatat actattcgtg
     3301 gtgattcccc aagttagtaa aaaagaatat attagtaaag taaatttaat gtatctcatt
     3361 ttttcaatcc cccctaatcg tatatatgta attattgcaa ataatgtcta catagtgtga
     3421 taaactgctg gaatggtagc aataactact tatttggact atttaccaaa taagtaagaa
     3481 atagtgctag ttaagaaatt tagcattgga tgtattatga aaatagtata atgaagatgt
     3541 aattaataga gctctttaat tatatgtaga aggtgagatt tctatgaaag cgatttttaa
     3601 aggtaaagaa gtacaagtat ggcagataag caaaacagca gaacaacccg aatggataaa
     3661 agaagcgttt aaagctaact atctaaagtg gtcaggtgat aaattgttat ttattatgaa
     3721 tggagttaag gcaccggtta aaattagtgc ttggacgaac tttaagactt tatttaatgg
     3781 agcttcaggt tggtgggcaa cttatgcaag tgggtatata ggcgattact tggattttac
     3841 taatcgcaaa attataccag aaagaaaatt taaaaagaag tacaaaattg ttaataaata
     3901 agcctatcag gtgtaatttg gtacctgata ggcttattgt tatcttcctg aaatcaagaa
     3961 aaatttaatg atggaaataa aaataaataa taactgtaac acaaaatcaa ttctatttag
     4021 tggatgcttg tcatcagtag attcaaaata gtgaaaatgt agcatggttg taaccaaaga
     4081 agaaaaggct agtataccaa gatgaattag atttccatca actaatgtcc agatcaatag
     4141 gagtaaagta attagtgaaa cagaaatttt gctgaaatta atattattag aaaaactatt
     4201 cataattttt acctcaattc attataaaag tatttttatt attacataga aagtaataaa
     4261 ttgaagagat ttttccaatt tggtaataag tggtgcctat ctggttgaaa aaagagaata
     4321 agaataaaat ttagcaaaat tagaaaaaat agtcaaaaag agcagatgaa gtgaataatt
     4381 ataagtgtaa attatagcta taattaattt ttaaaattat gaggtgttga agttatgaat
     4441 aataattttg tacaagttga taagaaagaa ttggcacata taattggtgg aagaaattct
     4501 tatgattata tagatagcgg acagtttggt tacgatatag gatgtacaat tgctaatact
     4561 aaatttttca aaagattaag acactcaaat caaaatattt gtagttaaaa agaaatgtaa
     4621 ccaactaggt atagaataac gtattttacg ctaaatcgat atttgaatac ggaatgataa
     4681 tacaataaaa gtgtaagtat atgtttcaca agtgttttag agaggatgtg tttttacatg
     4741 ctaaaaaaac tatgggagac ttggttggat ggtggattca ttagaggaaa gaagagatat
     4801 gttattgctc cagttatttg ggcactattg attccactag gaatatggtt gtttggtaat
     4861 gagggaatgt cttatttaga ttatatccag acgcctaaaa tgataatagt tactattttt
     4921 tgtctaatag gtggtagtac actactttat ttattagata ctgcaatgaa ggtaaataaa
     4981 catatgaaag gatgattatc atgatgaagg aatttacagt attgacagaa tgtgaattag
     5041 caaaggttga tggtgggaaa cgtggaccta actgtgtagg taacttctta ggtggtctat
     5101 ttgctggagc agctgcagga gttccacttg gaccagctgg tatcgtaggt ggggcaaatc
     5161 taggaatggt aggcggagcg cttacttgtt tataatatag gagtgattta agatgaaaaa
     5221 tctagataaa agattcacaa ttatgactga agataactta gcatcagtaa atggtggtaa
     5281 aaatggttat ggtggtagcg gaaatcgctg ggttcactgt ggagctggca tcgtaggtgg
     5341 agctttaatt ggagctatcg gtggaccctg gtcagccgta gcgggtggaa tttctggtgg
     5401 atttgcaagt tgccattaat ataaatctaa aaaattagaa attaatctat ttttcttcaa
     5461 gtagtgtcaa gtgtaagtta tagtatatag ctaaatttga cactactttt atttttaata
     5521 gaatacaata tattttaagg ttaggaagtg agtacatgat attttgggtt acagtaatag
     5581 tggcatatag tatctttatc agtatctata ctagtaaaaa agaagatggt catttgataa
     5641 aagaatttta aaatacaata agaaaataag ttatgtgagg gcgtgggtgt taaactttat
     5701 gtggtggtta tggttttaaa aatttcatcc aaccaaataa gcattaaaat gaaccgaata
     5761 tgataaaaga tgaataaagt agattaaaaa atgttaaact atatttgtaa taaagataac
     5821 aaaggagaga ctttttatga aatttgaagt gttaacagaa aagaagttac aagttattgt
     5881 aggtgggacg acaaaaaatt ggggaaaatc acagtataag aagtgcttat ttaatttttt
     5941 tggaacttgt aagtgatgat gtcattgaac agtgaagtag attattttat atcagttatt
     6001 tctttatttt taggcataat ctttgactat gtgttttttt atttaatatc accaattaaa
     6061 aaaaatataa aaaaagatag tatttttata tgtaccacat ttccactagt atttatattt
     6121 agtggtgctg gggataggat ggctttctat acagaattag tggaagttac cctattttat
     6181 tttgtatata aaagaagaat tatagattat ggaatattag gcagattatt attaatacaa
     6241 tcatattcgt atattacata tggagttgaa aatctatttt ttcaacttat aggcaaacag
     6301 gatacaagta ttaattcaat gatatgtgga tttatatttg tattaataga gtatatatta
     6361 tttactaaaa ccactgtcgt agagaattta gataatgagt atggaaaagt ctattttttc
     6421 ctaattttat atttatattt tggctcaata gctgtctatt acttagctaa ctacgttata
     6481 aaaatagata tattagcata tacaatcgct ataataatta ttataggtca attaattttc
     6541 tcactatata tctataatag tagtaaaaaa attagacaag ataaattaag tttacaacaa
     6601 attaaagatt taaagaccta tacgcaacag ttagaaagta gccagcgaag tttacgtaaa
     6661 tttaaacatg actaccaaaa tatgttgtta agcttgaagc ttagtgcaga gaaaaatcat
     6721 gataaagagt taatagataa actggctgaa tattcgagta agatcttaga agataaagta
     6781 ttatggcagt ttaatgatgt tgacaatatt aaagatgaat tgttaaagag tttatttatc
     6841 agtaagttga atagaatctt tcaagataat attcaatact cttttgaatg tcgggatgtg
     6901 atagatagtt tatcgaataa gtataatgca tttgatatca ttagaatatt agggattacg
     6961 tatgataatg caattgaaga aagtcttgaa cttggcgatg aagctaggat agacacaatg
     7021 gtttatcgag agaatggtga gcttgaaata gaaattaaga atcgttgtcg aaatacagac
     7081 ttaacaattc aagatatgag aaaatcaggt tttacaacta agaagaatca tgatggatta
     7141 ggattagcta atatagaaga attaagtcaa ccttataatg atatttttat caattatcag
     7201 attaaagatg gttggtttac tttccttatg gttatgagca tttaaggggt agtttaattt
     7261 ggaagaatat ggaattatta tttgtgacga tgagaaggat caagttagaa ggatacatga
     7321 tttagttaaa tatgctattt ggtctttaga agattctgct gacagtaaag ataaagagtt
     7381 taaaataact ttagaagcta atagttatat tgaagtagct gactatttag aagataacaa
     7441 agtagatagt ggagtttatt ttttagatat cgagcttagt agggatagag cagataaaga
     7501 tggcatagat ttagctgaat ttattagaca aagagatcca aatgcacaga taatttttat
     7561 tacggcttat gaaaatctag cagcaatgac ctatcgacgt cgcacaggag cgttggattt
     7621 tattactaaa aatgatagtg atgaagtgat tcaaaagcga ctaaatgaga ctttatcatt
     7681 agctgcaagg agaattaggg aatctcatgc cataaagaaa atgacattta gctataaaat
     7741 gggcagaaga attattaacg aaaatatcaa tgatattcta tatattatta ccactcctaa
     7801 gtcacataga ttgaaaatag ttacagttaa tggtatgggt gagtttacag gtgatattaa
     7861 gaagttagag gtagaaaatg attttctaga aaaaatatca caatcttgtt tagctaatcc
     7921 aagtaatatt gttgaaatta acctgtcaac aagggttatt tcttttaaag atggatataa
     7981 agagactttt cctagaagaa gtaaggctaa aatgaaaagt ttgattgaaa ggtataattt
     8041 gaaaacagtt taatcttttg tgtttattga tataggtggt gaaaatgaca tggtagaaat
     8101 aggtattatt atattgctaa ttgtagggtt tatggtaatt tcaaggttga aagtgaattt
     8161 tacgagaaat agtaagtata cagggtttct attattaata ttactgaatt taaatgggct
     8221 tatgcgaact cctatgttaa cagtaaaagg tttagtcttg ttgggaacat taatgatttt
     8281 tgtagttatg ttgattaagg aaattaaaca aaatagaata tatagttaat gaagagggtt
     8341 ggaacttagg gtattccaac cctctttata tgacattcta taattatctt tgcaaatgtt
     8401 tattcactct tattaatata tttacaatat aaagtaatgg accgctaaat atgttaaaca
     8461 aaattagata aaagttagaa aatctaaagt tagtattcac ctcttcaatg tagttgcaat
     8521 tatagaaatt aatcccatca tacaaaaaat taaaggatat aagttattac tattaaacaa
     8581 cattaggatt cttgcacata tattggctat accaataaag tagtctattc ttttattcac
     8641 ttttccctca tccttattta agacaattac ctatagttat tgtatttcaa atgaaagata
     8701 ggatgatttt tcaagcctaa tatgaacttt ttaaagcgta tttggttaag ccagatatgt
     8761 attaaaaaag acctaattcg ataatttagg cacgatgatt tgggaacatg atatgcttaa
     8821 taataaaaaa gatgaaagat aataagttta atagggggat attaacttat gatacataaa
     8881 tacaaaaaat attatatccc acaagtagat gaatctgatt gtggcgtagc ttcgttggct
     8941 atgattttga aacactatgg atcatcgcta tcactagcgt atttaagaaa tattgctaag
     9001 acaacaatgg aggggactac agctttaggt ctcgttaaga cagcacaggc tttaggaatg
     9061 gaaacacaag ccgtaaaggc tgatatgtcc ctttttgaaa tgaaagacat tacatatcca
     9121 tttattgtac atgtggttaa agaagaaacg ttattacatt attatgtagt attgaaagca
     9181 acgcctagat atattttaat tgctgatcca gctccagatg tagggataac taaaatgtcg
     9241 tatgaacgtt ttgaaaaaga atggacagga attactttat tcatcgttct aggaattgaa
     9301 tacaagccga caaaagaaac tagacaatca ttaatatcac tatttagtaa attatttaag
     9361 caaaagcaac taatagttaa tattgtattg gcagctttgt taattacaat tattagtata
     9421 ttgggatcat attttttaca gggaataatt gatacatata ttcctaatgg tatgcatagt
     9481 acactggcaa ttattacttt gggattacta gtaatatatg tgttcaattc aatttttaca
     9541 tatgcaaggg attttttatt agcaatttta gggcaacgac tttcgattga aattatttta
     9601 agttatatta gacatatttt tgagttgcct atggaatttt ttgcgaccag aaaaactgga
     9661 gaaatagtct ctcgttttaa tgatgctagt aaaattatag atgctttagc aagtactgtg
     9721 gtatctattt ttttagatgt aagtattgta gttattatgg gaataatctt ggctattcaa
     9781 aatcttaaat tactaggaat aactcttatc tcacttccaa tttacacgat tattattctt
     9841 acatttacaa aggcatttga aagattgaat aataaacaaa tggaaagtaa tgcgatactt
     9901 agttcatcta ttattgaaga tattcaagga atagaaacaa taaaagcctt aaacagcgaa
     9961 caaatgcgtt accgcaaaat tgatagtcaa tttgtggact atttgcgtaa atcgttagca
    10021 tatataaaga cagactcgtt gcaacaagca ttaaagttat ttattcaaca aacattaaat
    10081 gttacagtcc tatggttagg ggcaaatctg gtaattagta atcaactctc tataggacaa
    10141 ttaatgactt ttaacgcact attaagttat tttgtgaatc cattacaaaa tatcataaat
    10201 ttacagccaa aattgcagag tgcaagggta gctcacaatc gtttgaatga ggtttactta
    10261 gttgaaagtg aatttaaaga tagaaaagct gttcatgatg tcactcaact tcaaggaaat
    10321 attatagttc aagatgttga ctatcgctat ggatatggtg aaaatgtttt ggataaggtt
    10381 aatttgactt taaaacaggg agaaaaacta actatagtag gtatgagtgg ctctggcaaa
    10441 tcaacgttag ttaaactatt ggtgaatttt tttgccccag tttcaggtag tataaaacta
    10501 aataatcatg atataaataa cattgataag catactctgc gttcttatat taattacata
    10561 ccacagaatc catatatttt tgctgggaca atagaagata atcttagact aggtaatcga
    10621 tctaatgtga ctgatgagga tattctcatg gcttgcaaaa tagcaatgat tgatacagat
    10681 atagcgaaga tgccactaca attgaaaact gaactagatg aaaatgctaa tattttatca
    10741 ggtggacaaa aacaaagaat tacaattgct agagccttat tatctccagc acaagtattg
    10801 atttttgatg aatctacaag tggattagat gccattacgg agaaaaaact aattgataat
    10861 ttaatgaaat taaagtcaaa aactataatt tttattgcac atagattatc tatagctaag
    10921 cgaacaaata atattctagt attagatagc ggaaaaattg tagaaaaggg tagacatgat
    10981 gaattattag ctaaaaaagg atactactac aatttagtta atagttaggg gggagtattg
    11041 tattatggaa gataaatttt tagaaagcag cgaattttat tcagctagat ttagaaactt
    11101 ttcaactatg attattattc cttttacaat tttattgttg gcggtagtaa tttttagctt
    11161 ttttggaaaa aaagagataa ctatccaagg tgcaggaacg cttgaggcat tgggaaacaa
    11221 tcctgttatt caatcaactg taaatagtcc tattgaaaaa aattatttaa aagagggaaa
    11281 gtatgtaaaa aaaggagata cattacttgt ttataataat gtgagtatac aagataaggg
    11341 gaagctgtat aattcacaaa aagaaatctt agatagacag ttggcagctt tgaacttact
    11401 taaacaaggt gttcaagaca atcatgattc ttttggagaa gatgatgaat ttggttaccg
    11461 taatgattta aagagttacc tacaacaaag gaatacgtat ttaacagaaa atacaatgat
    11521 ccaggataaa tctaaaaacg acaaagccaa acaaagttcg attaataacg agttgaaaaa
    11581 acagggtgca tcctctacaa gtatagctga atttgattcg tctaagtaca atattgagat
    11641 aaacaatcaa aaaatgagtg atttacagtc aagtaagtta agttctattg atcaagaaat
    11701 tataaaaatc aagcaaaata tttcagaatt gaacgctaat attgatgaaa acaataatac
    11761 taacagagaa tataaggtaa aggctgttag agacggaatt ttacatatta acgatgagta
    11821 tagtgaaagt cattatataa gtgcaggggc taatttagct cagatactgc caattttgaa
    11881 aaatcaaaaa actttaaaaa taaaggcata tataagtaca gcagatattt cttccataaa
    11941 agtagggcaa aaagtaagat tcaaagtaac tagaaacgta cctaaaccta ttattttgac
    12001 tggaaaaata tacaagatat ccatttctcc agtagagata gggaaagaga attattatca
    12061 aattgaagct aaaacagata ttcaaaatac caatagggat ttattgaagt atggtatgca
    12121 agggcaaatg gttgtaatta caggtaagac aacatttttt gagtattata agaataagtt
    12181 atttaacatt aaacaataaa agctttttga atattcctta ctattaaact actggtagat
    12241 ttttatttcg taaagattag ggtaggatta ttgtagatta acaagtaagg atgagtgaca
    12301 tggaagaaaa atttttgaat tatgatatac caaattttgt aaaagaatca cctaattatc
    12361 taaaattatt tgaaaaagaa cgtatcatcc taaagaataa acatgataaa tgggggatct
    12421 actttagtga ggaattaggg catccattgg aatataagga aaattcagga aaagtagatt
    12481 atatatatga ttctttcttt gaagcctact ctcaagctga taatgacgga gaagtttggt
    12541 tttcagatga aatagcacat gaagtatttg gtgaacctga agatgaagat tttaatgaaa
    12601 aaggagaatt tgggagtttg agcgatgatt tcttttggac aaagaatcat ctaattttca
    12661 gacaccatgg tgattataat gttaagaatc tagaaaatga gtatcaagaa tggaaaaatt
    12721 tggataaaaa ggttaaagaa gacagtttta cgcatgaaaa ttttctatta atttatgaat
    12781 ggcttaggac acatcctaat ttctggaaag aaaatgttca tggggatagg gtcttctggg
    12841 agacatcaca catgaattta aactttatgg atatttatcc aacttctagt gaaacaaatg
    12901 gaaaagtaga atggtgggct gaaggtggat atcatgtttt agatgatact gatgtcccat
    12961 atgcaacaac ttactatcat gatattgctt tagactgtgg tggtaataca tatgagcaag
    13021 cagtactgaa ttttgcgaaa aacatttggt tacaaacaca tggaatgttg aaggataaag
    13081 aagcaaaacg tgacgctatc tttgaaagat gggctaagga ttctggatgc gaatctgact
    13141 gaatacttaa gataaaattt aatagcttac gccaagtaaa aatcgccaag gattagtgca
    13201 aatctttggc gattttttaa atttttccgg tttctacttg aaagttaatc atggtgcaaa
    13261 aggcattcct aatgctaaaa aaatgccaac gaaaattaaa aatagtatag gacttaatcc
    13321 taatataaaa gaaaatatat accaaagaga atgagagtgt ttattataaa ttacagaaaa
    13381 aacacataca aaaatagcca aaactaatat aagaatagtt cctatattgg aatccgttaa
    13441 aaatagacga gtattcggaa tccaagttag tagtgcaaca acaatagata aaataaataa
    13501 taaatatttt ttcattttaa ttatctcctt atgataagaa agggcaaaaa ctacttttct
    13561 tttggagttt cataaacaaa attattaaag tcaatattga gcaagttttg acgataatat
    13621 actaatgact taatagatag atgaagatga tctagaagtt caatttcgga tttatcttta
    13681 ttagtaagga gataattgta aatgtaactc tgtcttaatt ttgaaggagc tagtgtcata
    13741 ttcaaaattt cttcatcagg tctaactctc attaataatg aatttagcga attcaatggt
    13801 ttctcaggat cgttttttag tgagaatacg aaataattat caggttttat ttcaatatta
    13861 tctagcaaaa tttcagtatt ttctgtatca aaatttcgaa gctgcccaaa agtaatatta
    13921 agtaatccct ttggttcgat attttgagag attagaaaaa gctctaattt ggcatcatca
    13981 gaaagttctg caatcttgaa aatttcaggt agatattgct gccaaccaag tgtaatatta
    14041 gtgtatttat tgactttgta agtttttaaa tcgattaaag gatattcatc aatcaaatga
    14101 ttactataga gaaaagtaaa atactttttc aagtgaaaat agtatttatt agcagtatta
    14161 gcaacaatat gatgttgttc ttgaatattt acaagatagt tagtgatatc ttgaggtcgg
    14221 acaagacgaa tatcattacc atgttctgat tgactataaa aatagttata gaaactattg
    14281 acggtataat cgtacaacat tacggtactt tcgcgataat gtttaacatc tttagcccaa
    14341 gatagaaatt tttcacgata aggatactcc atatataaca cctcactaaa aattacgttg
    14401 caactataac tattcaaatt atatcatata caaaaacttt ctaaaaagaa tcactgaaaa
    14461 taatttttta taaagtatta ttaaggatta atgatcccaa gacgtatata aataagtttt
    14521 aatattttaa aataagtatt tgtaattaaa taattaaaaa atattgacaa aaacatttta
    14581 tgggcgtaat gtaaaagcat attgatgacc ataatatagg ggttgatagc gatgaatttt
    14641 gatgataatg aagaattagt aaataagcaa gttgacatga atgcttattc gcataactta
    14701 ttaaaagaaa aatatcctac gaaacaagat gtgattactg aaattatgaa cttggaagca
    14761 attttgcatc ttccaaaggg aactgaacac tttgtaagtg atttgcatgg ggagtataca
    14821 gcatttgatc acgttttaag aaatggttct ggaagtatta aacagaaaat tcaagactat
    14881 ttttcagata gaatgacgga acaaacgatg caagattttg ctttgctaat ctactatcct
    14941 gaagatgaat tggctctagt aaagaaaaaa ttacgtacag aaaatgagct acaacaatgg
    15001 tacttagata acatttccca cttattagaa tttttagaat tatcaggaag caagtatacg
    15061 cgctcaaagg ttcgtaaagc actaaatcct aattttgtat atataacaga agaattatta
    15121 tataacgatc cacaagaatt taataagaga agttatatta atcaactttt gaagaatatt
    15181 ttgaaattag atcaagcaga taaatttatt attgctacct gttacacaat tcaaagatta
    15241 gtagtagatc acttacatgt tctaggcgat gtttacgata ggggagaaga accagacaaa
    15301 attatggata gattgatgaa ttatcattct gtcgatatgc aatggggaaa tcatgattta
    15361 ctatggttag gtgcaatggc aggctcaaaa ctatgtatgt tgaatttatt gagaatttgt
    15421 gcaagatata ataacttgaa catcatagaa gatgcttatg ggattaactt acgtcacctt
    15481 tcgagatttg ctgaggagca atatgaggat aatcctcaat ttagacctaa attgactaat
    15541 ggtgatgggt atagattcaa cggcgaaaag ctacaaatca cgcaaattca tcaagctgtt
    15601 gcgatgatgc aatttaagct tgaagggcaa gttatagcta gaagaccaga attggaaatg
    15661 gatgatcgag atttacttaa taagatagat tacaagaaaa atgtaattag cttaaatggt
    15721 aaagaatatc cgttacaaaa tacttgtttc aacacagtag accctaaaaa tcctagtgaa
    15781 ttaacagatg aagaaaatgc gattgtagat gaattattaa tttccattca acattctaca
    15841 aaattaaaac gtcatctaga tttcatgatg aataaaggta gtatgtaccg tacgtataat
    15901 ggcaatctcc tattccatgg atgtattcct gcagatgaag aaggaaattt ctgtagctta
    15961 aagattggta gtaaagaata ttctggcaaa aaattgtttg atttttctga aaaaatgatt
    16021 cgaaaagc
//
