LOCUS       c00227_gnlPro..        12345 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BGDDINPK_227.
ACCESSION   c00227_gnlPro..
VERSION     c00227_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-05-01 01:05:50
            Original ID  :: gnl|Prokka|BGDDINPK_227
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12345
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..441)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTA_PTB"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg227_1"
                     /sec_met_domain="PTA_PTB (E-value: 1.7e-11, bitscore: 33.7,
                     seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLKDLIGKASIHKNKTIAVAHAEDEEVIRAVKLAAEHLSARFLL
                     TGDSTKLNELTSSMQGHQVEIVHADTPEESANLAVRAVHHKTADVLMKGNVPTSVLLKA
                     VLNRQEGLRSASVLSHVAVFDIPDFDRLMFVTDSAMNIACLLY"
     protocluster    1..12345
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[6581:9811]"
                     /cutoff="10000"
                     /detection_rule="(not (EC1_2-faecali or baiH or baiCD or
                     ECH1_Enoyl_CoA_DH1 or ECH1_Enoyl_CoA_DH2 or
                     ECH1_Enoyl_CoA_DH3 or ECH1_Enoyl_CoA_DH4 or POR or POR_N or
                     PFOR_II) and minimum(4, [AcetylCoA_hyd_C, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, EC1_2-faecali, ECH1_8_CARC, ECH_1, ECH_2,
                     HBT, HCDH, HCDH_N, Thiolase_C, Thiolase_N,
                     ketoacyl-synt]))"
                     /neighbourhood="10000"
                     /product="fatty_acids-unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      6582..9811
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(not (EC1_2-faecali or baiH or baiCD or
                     ECH1_Enoyl_CoA_DH1 or ECH1_Enoyl_CoA_DH2 or
                     ECH1_Enoyl_CoA_DH3 or ECH1_Enoyl_CoA_DH4 or POR or POR_N or
                     PFOR_II) and minimum(4, [AcetylCoA_hyd_C, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, EC1_2-faecali, ECH1_8_CARC, ECH_1, ECH_2,
                     HBT, HCDH, HCDH_N, Thiolase_C, Thiolase_N,
                     ketoacyl-synt]))"
                     /neighbourhood="10000"
                     /product="fatty_acids-unassigned"
                     /protocluster_number="1"
     cand_cluster    1..12345
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(not (EC1_2-faecali or baiH or baiCD or
                     ECH1_Enoyl_CoA_DH1 or ECH1_Enoyl_CoA_DH2 or
                     ECH1_Enoyl_CoA_DH3 or ECH1_Enoyl_CoA_DH4 or POR or POR_N or
                     PFOR_II) and minimum(4, [AcetylCoA_hyd_C, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, EC1_2-faecali, ECH1_8_CARC, ECH_1, ECH_2,
                     HBT, HCDH, HCDH_N, Thiolase_C, Thiolase_N,
                     ketoacyl-synt]))"
                     /kind="single"
                     /product="fatty_acids-unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12345
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="fatty_acids-unassigned"
                     /region_number="1"
                     /rules="(not (EC1_2-faecali or baiH or baiCD or
                     ECH1_Enoyl_CoA_DH1 or ECH1_Enoyl_CoA_DH2 or
                     ECH1_Enoyl_CoA_DH3 or ECH1_Enoyl_CoA_DH4 or POR or POR_N or
                     PFOR_II) and minimum(4, [AcetylCoA_hyd_C, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, EC1_2-faecali, ECH1_8_CARC, ECH_1, ECH_2,
                     HBT, HCDH, HCDH_N, Thiolase_C, Thiolase_N,
                     ketoacyl-synt]))"
                     /tool="gutsmash"
     CDS             complement(566..2644)
                     /locus_tag="ctg227_2"
                     /transl_table=11
                     /translation="MQKVLIVGAGKRGTALLHILIKTAIIDIIAVVDKDPEAPGLKEAE
                     QYGIAVSSDWKPYIQQKPDIVIHTTGDQAVFDELLQRKHEDTIVMPGKMAYIVFQLMEE
                     KQHLIQMLKEQTYKYDRIFNSTHDGMIFIDINEEIILFNHMAEKMVGKKREEVIGRPIK
                     EVIPSTKMPRILKTRVPEYNQKQLLGDHLQIVTTRLPIIDEGGRLLGALCVFKDITDAV
                     ELAEEVTNLKQVRTMLEAIIQSSDEAISVVDENGIGLLINKAYTKMTGLSEKEVIGKPA
                     NTDISEGESMHLKVLETRRPVRGVRMKVGPNEKEVIVNVAPVIVDGILKGSVGVIHDVS
                     EIKMLTAELNRARQIIRTLEAKYTFDDIIGKSEQMLVALEQAKLGAKTPATILLRGESG
                     TGKELFAHAIHNESDRKYNKFIRVNCAALSENLLESELFGYEDGAFSGAKRGGKKGLFE
                     EANNGSIFLDEIGELTQNMQAKLLRVLQEKEIVRVGGTKAIPVNVRVIAATNVNIEKAM
                     ADGTFREDLYYRINRYPISIPPLRQRLEDIEALSVRLIQKINRDYGRNVKGLSQQALRA
                     LSAYHWPGNVRELENVLGRAMIFLNPHMEWIEKDHLPVFELEQKENDTDQGTGFNFPDI
                     EGEKLSVAVEKFEAHLIQQTLEKHHFNRTKTAKALGVSIRNLYYKMDKYGLANEGMQ"
     CDS             complement(3075..3980)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PEP_mutase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg227_3"
                     /sec_met_domain="PEP_mutase (E-value: 1.6e-57, bitscore:
                     184.4, seeds: 82, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSWIVNKQSSQEELAGRFRKLMSAPDILQIPGAHDGMAALLAKEA
                     GFSAIYLSGAAYTASRGLPDLGIITSAEIAERAKDLVRAADLPLLVDIDTGFGGVLNAA
                     RTAREMLEARVAAVQIEDQQLPKKCGHLNGKQLVPIKEMAQKIKAIKQAAPSLIVVART
                     DARAQEGLDAAIKRSEAYIEAGADAIFPEALQAENEFRQFAERIPVPLLANMTEFGKTP
                     YYRADEFEDMGFHMVIYPVTSLRAAAKACERMFGLMKEHGSQKEGLHDMQTRKELYDTI
                     SYYDYEALDKTIAKTVLPDE"
     CDS             complement(3997..5433)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MmgE_PrpD"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg227_4"
                     /sec_met_domain="MmgE_PrpD (E-value: 7.8e-153, bitscore:
                     498.8, seeds: 231, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKGTGRMPKTDRVIEEITDYVLEKEITSAEAYTTAGHVLLDTLGC
                     GILALRYPECTKLLGPIVPGTTVPNGSKVPGTSYVLDPVRAAFNIGCMIRWLDYNDTWL
                     AAEWGHPSDNLGGILAATDYVSRVRLSEGKEPLTVRDVLVMMIKAHEIQGVLALENSLN
                     RVGLDHVLFVKVATTAVAAKLLGGGREEIKNALSNAWIDNAALRTYRHSPNTGSRKSWA
                     AGDATSRGVHLALMSLKGEMGYPTALSAPGWGFQDVLFNKKEIKLARPLDAYVMENVLF
                     KVSYPAEFHAQTAAECAVILHPQVKNRIDEIDRVVIRTHESAIRIIDKKGPLHNPADRD
                     HCLQYITAIGLLFGDITAQHYEAETASDPRIDKLRDKMEVTENKTYTEDYLKPDKRSIS
                     NAVQVHFKDGTSTEMVECEFPLGHRFRREEAVPKLLEKFSDNLKTHYPDKQHKHIYERC
                     TSYETLQTMRVNEFVDMFCM"
     CDS             complement(5430..6548)
                     /locus_tag="ctg227_5"
                     /transl_table=11
                     /translation="MEEKQHYSPGLDGVIAAETHISYLDTQSSQILIRGYDLIELSETK
                     SYLELVHLLLEGRLPEESEMETLERKINSASSLPADHLRLLELLPKDTHPMDSLRTGLS
                     ALAGYDRQIDDRSPSANKERAYQLLGKMPALTAASYRIINKKEPILPLQTLSYSANFLY
                     MMTGKLPSSLEEQIFDRSLVLYSEHEMPNSTFAARVIASTHSDLYGALTGAVASLKGNL
                     HGGANEAVMYLLLEAKTTSDFEQLLQTKLKRKEKIMGFGHRVYMKKMDPRALMMKEALQ
                     QLCDKAGDHRLYEMCEAGERLMEKEKGLYPNLDYYAAPVYWMLGIPIPLYTPIFFSART
                     SGLCAHVIEQHTNNRLFRPRVSYMGPRYQTKP"
     CDS             complement(6582..7058)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: Acyl-CoA_dh_1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg227_6"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 5.2e-59, bitscore:
                     188.6, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LLGKEGDGFHIAMANLNVGRIGIAAQSLGIAEAALEHAVDYAKQR
                     VQFGRPIAANQGISFKLADMATRAEAARDLVYHAADLHNRGLNCGKEASMAKQFASDAA
                     VKAALDAVQIYGGYGYMKDYPVERLLRDAKVTQIYEGTNEIQRLIISKYLLGGT"
     CDS             complement(7256..7714)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg227_7"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 2.8e-42, bitscore:
                     133.8, seeds: 796, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LHVTQEQIMMRKMVRDFARKEIAPAAEIMEKTDEFPFQLIKKMGE
                     HGLMGIPVPEQYGGAGADVVSYILAIHEISRISAAVGVILSVHTSVGTNPILYFGNEEQ
                     KMKYIPKLASGDHLGAFALTEPHSGSDAGSLRTTAIKKNGKYLLKKYS"
     CDS             complement(7742..8605)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: HCDH_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: HCDH"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg227_8"
                     /sec_met_domain="HCDH (E-value: 3.3e-40, bitscore: 126.5,
                     seeds: 68, tool: rule-based-clusters)"
                     /sec_met_domain="HCDH_N (E-value: 4e-70, bitscore: 225.1,
                     seeds: 60, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIKQIMVAGAGQMGSGIAQTAADAGFYVRMYDVNPEAAEAGLKR
                     LKKQLARDAEKGKRTETEVKSVISRISISQTLEEAEHADIVIEAIAENMAAKTEMFKTL
                     DRICPPHTILASNTSSLPITEIAAVTNRPQRVIGMHFMNPVPVMKLVEVIRGLATSEET
                     ALDVMALAEKMGKTAVEVNDFPGFVSNRVLLPMINEAIYCVYEGVAKPEAIDEVMKLGM
                     NHPMGPLALADFIGLDTCLSIMEVLHSGLGDSKYRPCPLLRKYVKAGWLGKKSGRGFYD
                     YEEKTS"
     CDS             complement(8630..9811)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: Thiolase_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: Thiolase_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg227_9"
                     /sec_met_domain="Thiolase_N (E-value: 9e-105, bitscore:
                     339.4, seeds: 30, tool: rule-based-clusters)"
                     /sec_met_domain="Thiolase_C (E-value: 5.9e-52, bitscore:
                     164.3, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKTVIVSAARTPFGKFGGVLKEVKAAELGGMVMKEALQRAGVSG
                     DDVEGNVMGMVVQAGSGQIPSRQAARLAGMPWSVPSETLNKVCASGLRAVTLCDQMIRA
                     QDADILVAGGMESMSNIPYAVPAGRWGARMGDGELRDLMVYDGLTCAFDEVHMAVHGNT
                     AAKEYAISRREQDEWALRSHARAAKAADEGKFQDEIVPVNWIGRKGKPNVVDKDEAIRR
                     DTSLDQLAKLAPIYASDGSITAGNAPGVNDGAGAFVLMSEEKAAELGKRPLATILGFST
                     TGMPAHELAAAPGFAINKLLKKNGLTVQDIDLFEVNEAFASVVLTCEKIVGFDLEKVNV
                     NGGAIALGHPIGASGARILMTLVYELKRRGGGLGVAAICSGAAQGDAVLVQVH"
     CDS             complement(9946..10677)
                     /locus_tag="ctg227_10"
                     /transl_table=11
                     /translation="MTKIFAHRGASGQFPENTMLAFEKGIEAGADGIELDVQLTKDGRI
                     VVIHDERLNRTTSLKGFVKDTTYDEVKTANAAAGHDQAYSDIKVPLLEDVLSWAVKKDF
                     LINIELKNSVIRYEGMEEKVLEAVKRFNVEDRVILSTFNHDSLALCARLAPHIERAVLT
                     SDVLYQADRYIASIPASGYHPKLNSPGVTDEVLKKMRNSSIKVRPYTVNRSEDMKRLIE
                     AGADGMFTDFPEKASALLKNE"
     CDS             complement(10756..11370)
                     /locus_tag="ctg227_11"
                     /transl_table=11
                     /translation="MLWRSLALCGLALTLAPCAQAAEPIEGKTVYIDAGHGGEDSGAVG
                     NGLFEKDINLAVSEHVTDKLKEEGANPVASRSDDHFLTLEERVAKASANQADLFVSIHV
                     NSGVASASGTETYFQSDYEGENSRRLASDIQSQLVSSLQTRDRGVKESDFYVITYSQMP
                     SVLAELGFITNSSDADKLGSEEYQQKAADAIVNGIDSYYDQ"
     CDS             complement(11396..11692)
                     /locus_tag="ctg227_12"
                     /transl_table=11
                     /translation="VKQTVLLLFTALFLSGCSVASADDSVPRFTEEGKYIGSADPHTIA
                     VSLNGEETMIQVPKDKRDECESLPDQTHVLVKYTKKDNGTLQLEDIQLRKNSS"
     CDS             12195..12344
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Oxidored_FMN"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg227_13"
                     /sec_met_domain="Oxidored_FMN (E-value: 8.3e-11, bitscore:
                     31.4, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VRIQTKEDDQMNPKYKPLFEPFTFKSGVTIDNRIAVAPMTHYASN
                     EDGTI"
ORIGIN
        1 gtataagaga caggcaatat tcattgccga atctgtcaca aacatcagcc ggtcaaaatc
       61 cggtatatcg aagacagcca cgtgagaaag gacacttgct gaccgaagcc cctcctgtct
      121 gttcaatacc gctttaagca aaacagaagt cggcacattg cctttcatta aaacgtccgc
      181 tgttttatga tgcacagcac gaaccgctaa attcgccgat tcctcaggag tatcggcatg
      241 gacgatttcc acttgatgcc cttgcatgga tgatgtcagc tcgttcagtt ttgtgctgtc
      301 gcccgttaac aagaaacggg cggataggtg ctcggctgcc agctttacag cccggatcac
      361 ttcctcatcc tcagcatgag caaccgcaat ggtcttattt ttgtgtatcg acgctttgcc
      421 gattaaatct ttcagcttca tctgttacca cctttcttgt ttcgactccg ccttttatta
      481 tgcaagttcc atgccagctc ttaagggtgc tgtcatacca ggtatattga aacattcgtg
      541 cagatgtttg cgtttattct gcaaattatt gcatgccttc atttgcaagg ccatatttat
      601 ccattttgta atataagttc cgaatgctga caccgagagc ttttgctgtt tttgtccggt
      661 taaaatgatg cttttcaagc gtttgctgga tcaaatgtgc ttcaaatttt tctactgcga
      721 cagacagctt ttcgccttca atatccggaa aattaaaacc tgttccctga tctgtgtcat
      781 tttctttttg ctcaagttcg aatacaggca agtgatcttt ttcaatccat tccatatgcg
      841 gattcagaaa aatcatggct cgtccaagga cattttcaag ctcccggaca ttcccaggcc
      901 aatggtaggc agataaggcg cgcaaggctt gctgtgagag cccttttaca ttcctgccgt
      961 aatcccggtt gatcttttgg ataagtctga cgctcaatgc ttcaatgtcc tccaaccgct
     1021 gccgcaaagg cgggatggag atcggatagc ggttgatccg gtaatacagg tcttcccgga
     1081 atgttccgtc cgccatcgcc ttttcaatat ttacatttgt cgccgcgatc actctgacat
     1141 tgacagggat cgctttcgtg ccgcccactc tgacgatttc cttttcttga aggacgcgta
     1201 gcaatttggc ctgcatattt tgtgtcagct caccgatttc atctaagaaa atactgccgt
     1261 tatttgcttc ctcaaataaa ccctttttac cgccgcgctt cgctcctgaa aacgcgccat
     1321 cctcatagcc gaacaattct gattcgagca ggttttcaga aagggctgca caattcacgc
     1381 gaataaattt attgtatttc cggtcacttt cgttatggat ggcatgggcg aacagttctt
     1441 ttcctgttcc tgattccccg cgcagcaaga tggttgccgg tgttttcgca ccgagcttcg
     1501 cctgctcaag cgcaaccagc atttgctcgc ttttgccgat aatgtcgtca aacgtgtatt
     1561 tcgcttcaag cgtgcgaata atttgtctgg cgcgattaag ctccgctgtc agcattttaa
     1621 tttcggaaac atcgtgaatc acgccgacgc tgcctttcaa aatcccgtcc acaatcaccg
     1681 gtgctacatt aacgatcact tctttttcat tcgggccgac cttcattctg acaccgcgga
     1741 caggacgtct tgtttcaagc acctttaaat gcatgctttc gccttcggaa atatcagtgt
     1801 ttgcaggctt gccgatgact tctttttcag aaagccccgt cattttcgta tacgctttat
     1861 tgattagcag gccgatgccg ttttcatcaa cgacagaaat cgcctcatcg gaggattgaa
     1921 taattgcctc cagcatcgta cggacctgct ttaagttggt cacttcctct gccagctcga
     1981 ccgcatcagt gatatcttta aaaacacaaa gagccccgag cagacgtccg ccttcatcaa
     2041 taatcggcag ccttgtggtc acaatttgca aatgatcgcc taacagctgc ttctggttgt
     2101 attcaggcac tcttgttttt aaaatccgcg gcatcttcgt gctcggaatc acttctttta
     2161 ttgggcgccc aatgacttcc tcacgttttt tcccgaccat tttttcggcc atatggttaa
     2221 agagaatgat ttcttcattg atatcaataa aaatcattcc atcatgggtg gaattaaaaa
     2281 ttctgtcata tttataggtt tgctctttta gcatttgaat caggtgctgc ttttcttcca
     2341 tcagctgaaa aacgatgtat gccatttttc ccggcatgac aatggtatct tcatgctttc
     2401 tttgaaggag ctcgtcaaac acggcttgat cgccggtagt atgaatgacg atatccggtt
     2461 tttgttgtat gtaaggtttc caatcagatg atacggcaat cccatactgt tctgcttctt
     2521 tcaatcccgg cgcctcgggg tctttgtcaa ctacggcaat gatatctatg atggctgttt
     2581 taatcagaat atgtaataac gccgttcccc ttttgccggc acctactatc agtacctttt
     2641 gcatcccgat acccctttgt atgaaaaaat ttgcacacct atttattccg ttgcaataat
     2701 ttgcacaacc ctatgttacc acgttttctt ctcttgacaa aatatttttt ccgctggaca
     2761 ataaaggaaa tgaaaagata aaggggtttt ctgaagatga gccgacttct tgcgctttta
     2821 atattagtca tccccggggc tatttctgct ttaggcatta aactgatgag agatacactt
     2881 ttcggccata caatcaagcc attttcagct ctttggctcc aagggttgtc aggattcatc
     2941 ttttttgcga tcggcctcta tgtgctggcc gggttcattt tatacagaga cagaaaacgc
     3001 aatcaagtca gcccgcgatt cagaaaacga tagctgaaaa aaagccggag aatgctccgg
     3061 ctttttttgt tgcattattc gtcaggcaaa acggtcttgg caatcgtttt gtctaacgct
     3121 tcatagtcat aataagaaat cgtatcgtac agttcttttc gtgtctgcat atcatgaagt
     3181 ccttcttttt gtgagccgtg ctccttcatc aaaccaaaca tccgctcaca agcttttgcc
     3241 gccgctcgaa gcgaggtgac aggatatatc accatgtgaa accccatatc ttcgaattca
     3301 tcggcacgat aatatggcgt tttcccaaat tcagtcatat tcgcaaggag cggaacgggg
     3361 atacgctcag caaactggcg gaattcattc tccgcctgca gcgcttccgg gaaaattgcg
     3421 tccgctcccg cctcaatgta agcctctgaa cgttttattg cggcatcaag cccttcctgc
     3481 gccctggcat cagtacgggc aacaacaata agggagggtg ccgcttgttt aatggctttt
     3541 attttttgcg ccatttcctt gatcggaact agctgtttgc catttaaatg tccgcatttt
     3601 tttggaagct gctggtcttc tatttgaacg gctgctaccc ttgcttcaag catctcccgg
     3661 gctgttcggg cggcatttaa gacaccgcca aatcccgtat cgatatccac aagcagaggc
     3721 agatcagctg cacgtacaag atctttggcc cgttcagcta tctctgccga tgtgatgatc
     3781 cctaaatcag gcagccccct gctggctgta taggcagcac cggacaaata aatagcagaa
     3841 aaaccggctt ctttcgcaag caaagcggcc atcccgtcat gggcgccggg aatttgaaga
     3901 atgtccggtg ctgacatcag cttgcggaaa cgcccggcaa gctcctcttg tgacgattgc
     3961 ttattgacga tccacgacat gaaacaaatc ccccttttac atgcagaaca tgtctacgaa
     4021 ttcatttacg cgcatcgttt gtaatgtctc atagctggta cagcgctcat aaatgtgttt
     4081 gtgctgttta tcaggataat gggttttgag attgtcagaa aacttttcca acagtttcgg
     4141 cactgcttcc tctcttcgaa aacgatggcc gaggggaaac tcacattcca ccatttccgt
     4201 gctcgttccg tctttaaaat gaacctgaac ggcatttgag atggaacgtt tatcaggttt
     4261 caaataatcc tcggtatatg ttttattttc agtcacctcc attttatcac gaagtttatc
     4321 tattctcgga tcactcgctg tttcagcttc ataatgctgt gccgtgatat caccaaaaag
     4381 caaaccgatt gctgtaatgt attggaggca gtgatcacgg tctgccggat tgtggagcgg
     4441 gcctttttta tcaatgattc ggatagcgga ttcatgcgtt ctgatgacaa cacggtcaat
     4501 ctcgtcaatc cggttcttta cctgcgggtg aagaatgacg gcgcactccg ccgctgtctg
     4561 ggcgtgaaat tccgcaggat aagacacttt aaataacaca ttttccatga cataagcgtc
     4621 gagaggacgg gcaagcttga tctctttctt attgaataaa acgtcttgga acccccaacc
     4681 cggtgcactc agggctgtcg gataacccat ttcccctttt aacgacatca gcgccaaatg
     4741 aacacctctg cttgttgcgt ctcctgccgc ccatgattta cgcgagcctg tattcggtga
     4801 atggcggtat gtcctcaatg ctgcattgtc aatccatgca ttcgaaagcg catttttgat
     4861 ttcttctctt ccgccgccca aaagctttgc cgcaacagca gttgtcgcaa ctttgacaaa
     4921 cagcacatgg tcaaggccaa ctcgatttaa gctgttttct aacgccagca caccttgaat
     4981 ctcgtgtgct ttgatcatca tcacaagtac gtcgcgtacc gttaacggct cttttccttc
     5041 agacagcctc actcttgata cataatcagt agcggcaagg attcctccca agttatcgga
     5101 tggatgcccc cactccgccg ccagccacgt atcgttgtaa tcgagccagc gaatcatgca
     5161 gccgatatta aacgctgccc tcacaggatc gagaacatat gacgttcccg gcactttgct
     5221 tccattcggc acagtcgttc ctggaacaat cgggccaagc agctttgtgc attccggata
     5281 ccgtagcgcc aagatcccgc agcccagggt atccagcaat acatgccccg ctgttgtata
     5341 cgcttcggca ctagtaatct ctttctcaag cacatagtct gtgatttctt cgataacacg
     5401 atccgttttc ggcattctac cagttccttt catggttttg tttgatatcg cgggcccatg
     5461 taactgacac ggggacggaa gagccgatta ttggtatgct gttcgatcac atgggcgcat
     5521 aaaccggacg ttctcgcgct gaaaaagatc ggcgtatata aaggaatcgg tatgccgagc
     5581 atccaataca ctggggcagc atagtaatcc aaattcgggt aaagcccttt ttccttctcc
     5641 atcagccgct cacccgcttc gcacatctca tataaacgat ggtcaccggc tttatcgcat
     5701 aattgctgca gcgcctcttt catcatgagt gctctcgggt ccattttttt catatacacc
     5761 cggtggccga agcccatgat tttttctttt cttttcagtt ttgtttgcaa aagctgctca
     5821 aaatcagatg tcgtttttgc ctccaaaagc aaatacatca cagcttcgtt tgctcctccg
     5881 tgaagattcc ctttcaggga agcgacagcc ccagtcaaag ccccataaag atctgaatgt
     5941 gtagatgcaa tgaccctggc cgcaaaggtt gaattcggca tctcatgctc actgtacagg
     6001 acgagcgacc ggtcaaaaat ctgttcttcc aatgaagacg gcaatttccc tgtcatcatg
     6061 tagagaaaat tcgcactgta ggatagggtt tgaagcggaa gaatcggttc tttcttatta
     6121 atgatcctgt agctggcagc agtgagggca ggcattttcc caagaagctg ataggcgcgt
     6181 tctttgtttg cggaaggaga ccgatcatca atttgccgat catagccagc aagtgccgac
     6241 aggccggtac gcagactatc cattggatga gtgtccttag ggagcagctc aagcagacgg
     6301 agatgatcag caggcaggct tgaggcactg tttattttac gttccagcgt ttccatttca
     6361 ctttcttctg gcagcctgcc ctccagcaat aaatggacaa gctccagata gctttttgtt
     6421 tcagaaagtt ctattaaatc atagccccgt atcaaaatct ggctggactg ggtgtcaaga
     6481 taagaaatat gagtttctgc cgcaatcaca ccgtccaacc ctggagaata atgctgtttc
     6541 tcctccatat cctcaacctc cgtttttgcg ttttttgtct atcaggttcc gccaagcaaa
     6601 tacttggaaa taatcagtct ttgaatctcg ttcgtccctt cataaatttg cgtcaccttt
     6661 gcatcgcgaa gcaagcgctc aaccggataa tccttcatat agccatatcc tccataaatt
     6721 tgaacggcgt ctaacgctgc cttcacggct gcatcggaag caaattgttt agccatagac
     6781 gcttcttttc cacaatttag gccgcggtta tgaaggtctg cggcgtggta gacaagatct
     6841 cttgccgcct ctgccctagt cgccatgtca gccagcttaa atgatatgcc ttgattggct
     6901 gcgatcggcc ttccaaattg cactcgctgc ttcgcataat caacggcatg ctcaagagcc
     6961 gcctctgcaa ttccgaggga ctgtgccgca atgccgatcc ggccgacatt taaattcgcc
     7021 atggcaatgt gaaagccatc cccctctttg ccaagcaaat tggcttcagg cacttctgca
     7081 ttatcaaaaa tcagttccgt agtattggag ccataaagcc ctagctttct ttcttttttc
     7141 ccaacggtaa aaccgggtgt gtttttttca acaataaaag ccgaaattcc gtgcctgcct
     7201 tgatctggag ctgttaaagc aaatgtgata tagatatcag ctgctccgcc attcgttatg
     7261 aatatttttt taatagatat ttgccgttct ttttgattgc tgttgtgcgg aggctcccgg
     7321 catccgaccc cgagtgaggc tccgttagtg caaacgcgcc caaatggtct cctgacgcga
     7381 gctttggtat atatttcatc ttctgttctt cgttgccgaa atacagaatc ggatttgtgc
     7441 cgactgaggt atgaacggag agaattacgc cgacagccgc actgattcta gaaatctcat
     7501 gaatcgccaa aatataagaa acaacgtccg ccccggcacc gccgtattgt tccggcaccg
     7561 gtattcccat caggccgtgt tcacccattt ttttgatcag ctgaaaggga aattcgtccg
     7621 ttttctccat gatttccgca gcgggagcaa tttcttttcg tgcaaaatca cgcaccattt
     7681 ttcgcatcat gatttgctct tgggttacat gcaactcggc cacccccgga tggaatagac
     7741 ttcaggaagt cttctcctca tagtcataaa aaccgcgtcc gctctttttg ccaagccagc
     7801 ctgctttgac atacttgcgg agcagcgggc aaggacggta tttggaatcg ccaaggcctg
     7861 agtgaagaac ttccataatt gataaacacg tatccagtcc gataaaatcc gctaatgcaa
     7921 gcggacccat cggatgattc atgcccagct tcatcacttc atctattgcc tccggcttcg
     7981 ccactccctc atacacgcaa tagatggctt cattaatcat tggaagaagc acacggttgg
     8041 aaacaaaccc aggaaaatca ttgacttcta ccgctgtttt ccccatcttt tccgctaatg
     8101 ccataacatc taaggccgtt tcttctgatg tagccaagcc tcgaatcact tctaccagct
     8161 tcattacagg gacgggattc ataaaatgca tgccaataac ccgttgaggc cggtttgtta
     8221 cagcagcgat ttctgtaata ggcaaggaag atgtattgct ggccaaaatc gtatgaggcg
     8281 ggcaaatgcg atcaagtgtt ttaaacatct cagtttttgc cgccatgttt tctgcgatag
     8341 cctcaatcac aatgtccgca tgctctgcct cctcaagcgt ttgagaaatc gaaatgcggc
     8401 tgattacgct cttcacttcc gtctcggtcc tttttccttt ctcagcatca cgggccagct
     8461 gtttcttcag ccgtttcaat cctgcctccg cggcctctgg attcacatca tacatccgca
     8521 cataaaagcc tgcgtcggca gctgtttgag caattccgct tcccatctga cctgcgccag
     8581 ctaccatgat ttgtttgatt tccattcaaa tccccttttt catcatgttt taatgaacct
     8641 gcactaagac ggcgtctccc tgtgctgccc cgctgcaaat agcggcaacg cccagacccc
     8701 ctcctcgtcg ctttaattca taaacaagcg tcatgagaat tctcgcaccg ctcgcgccga
     8761 tcgggtgtcc gagcgcgatc gcaccgccat ttacatttac tttttcaaga tcgaaaccta
     8821 cgattttttc acatgtcaaa acaactgaag caaaagcttc atttacttca aacaagtcaa
     8881 tatcttggac agttaaaccg ttctttttca ggagcttgtt aatggcaaac cccggcgctg
     8941 ccgccagctc gtgcgctggc attcccgtag ttgaaaaacc aagaattgta gccagaggcc
     9001 gtttgccaag ctcagcagct ttttcctcag acatcagcac gaacgcgccg gctccgtcat
     9061 tgactccagg agcattgccg gctgtgatag aaccgtcact tgcataaatc ggagcaagtt
     9121 tcgcgagctg atccagactt gtgtcacggc gaatcgcttc atctttatca acaacgtttg
     9181 gttttccttt tcgaccgatc cagttgacgg gaacaatttc atcctgaaac ttcccttcat
     9241 cggcggcctt agctgccctt gcatgacttc tcaacgccca ttcgtcctgc tctcttcgtg
     9301 agattgcata ttccttggca gctgtatttc cgtgaacagc catgtgcacc tcgtcaaatg
     9361 cgcacgttaa tccgtcatac accattaagt ccctaagctc gccgtccccc atccgtgctc
     9421 cccagcgccc ggcgggaacg gcatacggaa tattgctcat gctttccatc ccccccgcaa
     9481 caagtatgtc cgcatcctgc gcccgaatca tttgatcaca taaagtgaca gcgcgaaggc
     9541 cggaagcaca gactttattc agtgtttctg acggcacact ccaaggcatt cccgccagac
     9601 gggcagcttg acgggaaggt atctgccctg agccggcctg gacaaccatg cccatgacgt
     9661 ttccttctac atcatctcca gagactccag cccgttgcag cgcctccttc atcaccatgc
     9721 ccccaagctc agcagctttc acctctttca atactccgcc gaatttgcca aatggcgttc
     9781 ttgcagcact tacaatgact gttttcctca tggtttcacc tcattcagaa gatagacagc
     9841 gcttacaatt tctagttgtc ttctatgaat gtatgctttg aaacgggcat gaatgaatga
     9901 atgaatgaaa aaagaaggct gcgtcaaaca gcctccttct aacaactatt catttttcag
     9961 caatgccgaa gccttttctg gaaagtcggt aaacatgccg tctgctcccg cttcaatgag
    10021 acgcttcata tcttccgaac gattgactgt atacggcctt accttaatcg aactgttcct
    10081 cattttcttc agcacttcat ctgtgacccc tgggctgttt aacttcgggt gatagccgga
    10141 agccggaata gacgcgatat atcgatctgc ctgataaagc acatctgaag ttaatactgc
    10201 ccgttcgata tgcggcgcaa gccgggcgca tagcgccaag ctgtcatgat taaaggtgga
    10261 taggatgact ctgtcctcta cattgaatcg cttcactgcc tccagcactt tttcttccat
    10321 tccctcatag cggatcacgc tgttttttaa ttcaatgttg atgagaaaat ccttttttac
    10381 cgcccacgag agcacatctt ctagcagcgg cacttttata tcgctgtacg cttgatcgtg
    10441 accagcggcc gcattcgcag tctttacctc atcataggtt gtatccttca cgaatccttt
    10501 aagtgatgtc gtgcgattaa gtctttcatc atgaatcaca acaatgcgtc cgtctttcgt
    10561 cagctgtaca tcaagctcta tcccatccgc tccggcttca attccttttt caaatgcaag
    10621 cattgtattt tcgggaaatt gacctgatgc cccccggtgg gcaaaaatct ttgtcatcgt
    10681 ttcacctcaa accctaaagt tttctccatt atacttattt tgtcggctcc actctaggat
    10741 taaggctgta tcaatctact gatcataata agaatcaatg ccgttgacaa tcgcatctgc
    10801 ggccttttgc tggtattctt cacttcccag cttgtccgca tcagaactgt tagtgataaa
    10861 cccaagctcc gccaacacac ttggcatttg tgaatatgta atgacgtaaa agtctgattc
    10921 tttcacgccc ctgtctctcg tttgtaagga agaaacgagc tgtgactgaa tatcggatgc
    10981 cagacgccgg ctgttctccc cttcataatc agattgaaaa tacgtttctg ttcctgaagc
    11041 tgaagcaacc cctgaattca catgaatgct gacaaaaagg tcagcctgat tggcacttgc
    11101 cttagccact ctttcctcca aggtcagaaa atgatcgtca gaccgggatg caacaggatt
    11161 ggctccctcc tcttttagtt tgtctgtcac atgctctgag acagccaaat taatatcctt
    11221 ttcaaagagc ccgtttccga ccgctccact atcttcaccg ccgtgtccgg catcaatata
    11281 cactgttttc ccttctatcg gctctgctgc ctgtgcacaa ggcgcgagcg tcaaagccaa
    11341 tccgcacagc gccaagctcc tccataacat tctcaactta ctccctccgg tctttttatg
    11401 acgagttctt tcgcagctga atatcttcca gctgtaaagt tccattatcc ttctttgtat
    11461 atttcaccag gacatgtgtc tgatctggca gtgattcaca ttcatcacgt ttatccttcg
    11521 gaacttgtat catggtttct tctccattaa gagaaaccgc aatcgtatga ggatcagccg
    11581 agccaatgta ttttccctct tcggtaaacc ttggcactga gtcatccgca cttgcaacac
    11641 tgcaccccga aagaaagagc gcagtaaaca gcaaaagaac cgtttgtttc acatgaccac
    11701 ctcttcctga tgtttggctt ttatctttga ccagaatggc aaatttgtaa agacaacgcg
    11761 aatgcaggcg agcaagttcc atgattttca aaagggctat acgacccgat catttcctgt
    11821 tgttagaaag ataacgagca gatttgtcta tgaggatggc tctaattgag gcgccaatta
    11881 gaaaaaatta gcggaaagaa gcaacttttt attcatttta aaaaatttga gaatagggtg
    11941 agcaaatcgt ttgacgggtg ggtcagccaa gcgtaacctt ttaaaggata tttactttat
    12001 tgaaagaagt taaagccatg aaaaaattcg ttctgctgct ggcggcagct gtcatcacat
    12061 gctccatcgg ccaccaaatc agcggcggct acaaaggccc cgaaaaagag cggcgaaaac
    12121 atcactctgc actcaagata ttcagtcggt aaagcagatc aattgcatta atttttacat
    12181 ataggctaga atatgtgcga atccaaacga aagaagatga tcaaatgaat cctaagtata
    12241 agccactttt tgaaccattt acgtttaaaa gcggcgttac aatcgacaac cggatcgcag
    12301 tagcaccgat gactcattac gcttctaatg aagacggtac aatat
//
