LOCUS       c00231_gnlPro..        11017 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BGDDINPK_231.
ACCESSION   c00231_gnlPro..
VERSION     c00231_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-05-01 01:05:50
            Original ID  :: gnl|Prokka|BGDDINPK_231
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11017
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11017
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[5834:9126]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      5835..9126
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..11017
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..11017
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             2..811
                     /locus_tag="ctg231_1"
                     /transl_table=11
                     /translation="PKSESTAKQALEYLVQGGPVSEILPNGFRAVLPADTTVNVDIKKD
                     GTAIADFSNEFKNYKKEDEQKIVQSVTWTLTQFSSIDKVKLRINGHELKEMPVGGTPIS
                     DDLSRKDGINLETAGVNDLTATHPLTVYYLAENEDSEYYVPVTKRIDNSEKDDVTAAIN
                     ELAKGPSKVSGLLTDFSEDVKLVSKPKIKDGRVTLDFNQSIFGSADEKTKMISSEVLNS
                     IVLTLTEQPDIKGVSVKVNGKSELVNEKGEKLTEPVSRPSQVNTGSF"
     CDS             922..1659
                     /locus_tag="ctg231_2"
                     /transl_table=11
                     /translation="MRHDGRQHDELRPITFDLDFISHPEGSVLITAGNTKVICNASVED
                     RVPPFLRGGGKGWITAEYSMLPRATNQRTIRESSKGKISGRTMEIQRLIGRALRAVVDL
                     EKLGERTIWIDCDVIQADGGTRTASITGAFLAMAIAIGKLIKAGTIKTNPITDFLAAIS
                     VGIDKEQGILLDLNYEEDSSAEVDMNVIMTGSGRFVELQGTGEEATFSREDLNGLLGLA
                     EKGIQELIDKQKEVLGDSLPELK"
     CDS             1681..2268
                     /locus_tag="ctg231_3"
                     /transl_table=11
                     /translation="MKEAIIATHNPGKVKEFKEILEPRGYDVKSLAEIGFTEEIEETGH
                     TFEENAILKAEAVAKAVNKMVIADDSGLSIDNLGGRPGVYSARYAGEQKDDQANIEKVL
                     SELKGIEKEQRTARFRCALAVSIPGEETKTVEGHVEGYIAEEPRGEYGFGYDPIFIVKD
                     KDKTMAELTSDEKNKISHRADALKKLSKLLEA"
     CDS             2284..2793
                     /locus_tag="ctg231_4"
                     /transl_table=11
                     /translation="MNVLIISDSHGLEEELQTIAKRHEAEVDLMIHCGDSELETRHPAL
                     EPYAVVKGNCDFAGDFKDELLLTAGSRKILVTHGHLHGIKQTLLNVYYRAEELGADVIC
                     FGHSHIAGSEVLRGKLMINPGSIRLPRVRRTESYAILTLENDAATVRFYDQAGNEIEDL
                     QNRVTL"
     CDS             complement(3061..3885)
                     /locus_tag="ctg231_5"
                     /transl_table=11
                     /translation="MKSIVGVYETPQETIAAIEGLLTKGYDSDDISVVTSRRDTDYLES
                     RTGTEVNQAIDAHQDESESFFDKLKDYFTMDDTATHSKALSDLDIKTDEIDKYQEDLDD
                     GKLLVAVDTDADVIAPVDNGNALSSGFSGTNELDYTTKEEKTMPLREEQLKVDKEDVQT
                     GEVEIGKEVKTEKRDMDIPVRHDEIYVERRPVDENKTDAAPVNDSEEIRVPIVEEKLEV
                     TKKPVVTDEVVVGKRTVEENEHISETVKKEEPRLNKEGKVDGLDDDDPLNNK"
     CDS             complement(4069..4455)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg231_6"
                     /sec_met_domain="Acetyltransf_1 (E-value: 2e-15, bitscore:
                     46.8, seeds: 223, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLMSPPESIHALGLEKLRGPGITFWSAWEGDELAGCGALKELDS
                     WHGEVKSMRTSASHLRKGVAKQVLQHIIEEAEKRGYERLSLETGSMASFEPARKLYESF
                     GFQYCEPFADYDEDPNSVFMKKEL"
     CDS             5583..5771
                     /locus_tag="ctg231_7"
                     /transl_table=11
                     /translation="MTVGLGRVNLIHSLLKRIEISMRRPTKAVNKGGTAERKAFSPLLA
                     IAVTARLIVGGRAFFIE"
     CDS             5835..7559
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg231_8"
                     /sec_met_domain="TPP_enzyme_C (E-value: 9e-55, bitscore:
                     174.4, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTNVQVDSASAKCTQTMSGALMLIESLKKEKVEMIFGYPGGAVL
                     PIYDKLYNSGLVHILPRHEQGAIHAAEGYARVSGKPGVVIATSGPGATNLVTGLADAMI
                     DSLPLVVFTGQVATSVIGSDAFQEADILGITMPVTKHSYQVRQPEDLPRIIKEAFHIAT
                     TGRPGPVLIDIPKDVATIEGEFSYDHEMNLPGYQPTTEPNYLQIRKLVEAVSSAKKPVI
                     LAGAGVLHGKASEELKNYAEQQQIPVAHTLLGLGGFPADHPLFLGMAGMHGTYTANMAL
                     HECDLLISIGARFDDRVTGNLKHFARNAKIAHIDIDPAEIGKIMKTQIPVVGDSKIVLQ
                     ELIKQDGKQSDSSEWKKQLAEWKEEYPLWYVDNEEEGFKPQKLIEYIHQFTKGEAIVAT
                     DVGQHQMWSAQFYPFQKADKWVTSGGLGTMGFGLPAAIGAQLAEKDATVVAVVGDGGFQ
                     MTLQELDVIRELNLPVKVVILNNACLGMVRQWQEIFYEERYSESKFASQPDFVKLSEAY
                     GIKGIRISSEAEAKVKLEEALTSREPVVIDVRVASEEKVFPMVAPGKGLHEMVGVKP"
     CDS             7556..8074
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg231_9"
                     /sec_met_domain="ALS_ss_C (E-value: 2.1e-32, bitscore:
                     101.0, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LKRIITLTVVNRSGVLNRITGLFTKRHYNIESITVGHTETAGVSR
                     ITFVVHVEGENDVEQLTKQLNKQIDVLKVTDITNQSIVQRELALIKVVSAPSTRTEING
                     IIEPFRASVVDVSRDSIVVQVTGESNKIEALIELLKPYGIKEIARTGTTAFARGTQQKA
                     SSNKTISIV"
     CDS             8098..9126
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg231_10"
                     /sec_met_domain="IlvN (E-value: 1e-78, bitscore: 252.3,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 3.7e-69, bitscore: 221.3,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKVYYNGDIKENVLAGKTVAVIGYGSQGHAHALNLKESGVDVIV
                     GVRQGKSFTQAQEDGHKVFSVKEAAAQAEIIMVLLPDEQQQKVYEAEIKDELTAGKSLV
                     FAHGFNVHFHQIVPPADVDVFLVAPKGPGHLVRRTYEQGAGVPALFAIYQDVTGEARDK
                     ALAYAKGIGGARAGVLETTFKEETETDLFGEQAVLCGGLSALVKAGFETLTEAGYQPEL
                     AYFECLHELKLIVDLMYEEGLAGMRYSISDTAQWGDFVSGPRVVDAKVKESMKEVLKDI
                     QNGTFAKEWIVENQVNRPRFNAINASENEHQIEVVGRKLREMMPFVKQGKKKEAVVSVA
                     QN"
     CDS             9113..10669
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg231_11"
                     /sec_met_domain="HMGL-like (E-value: 1.2e-100, bitscore:
                     326.0, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LRKINFFDTTLRDGEQSPGVNLNTQEKLAIAKQLERLGADIIEAG
                     FPASSRGDFLAVQEIARTIKNCSVTGLARCVKGDIDAAWEALKDGAYPRIHVFIATSDI
                     HLKHKLKMTREQVIERAVEMVTYAKERFPVVQWSAEDACRTELPFLAEIVEKVIDAGAS
                     VINLPDTVGYLAPAEYGNIFKYMKENVPNIHKAKLSAHCHDDLGMAVANSLAAIENGAD
                     QIECAVNGIGERAGNAALEEIAVALHTRKDFYQVETGITLNEIKRTSDLVSKLTGMAVP
                     RNKAVVGDNAFAHESGIHQDGFLKEKSTYEIISPELVGVTADALVLGKHSGRHAFKDRL
                     TALGFQFDSEEINKFFTMFKELTEKKKEITDEDLVSLILEEKVTDRKIGYEFLSLQVHY
                     GTSQVPTATLSLKNQENAELIQEAATGAGSVEAIYNTLERCIDKDVELLDYRIQSNRKG
                     EDAFAQVYVRVLVNGKESAGRGIAQDVLEASAKAYLNAVNRQLVFQSNMSGLKNHTAVG
                     S"
     CDS             10690..11016
                     /locus_tag="ctg231_12"
                     /transl_table=11
                     /translation="LKKRIALLPGDGIGPEVLESATDVLKSVAERFNHEFEFEYGLIGG
                     AAIDEHHNPLPEETVAACKNADAILLGAVGGPKWDQNPSELRPEKGLLSIRKQLDLFAN
                     LRPVK"
ORIGIN
        1 ccctaaaagt gagagcacgg ctaagcaggc gcttgaatac ctcgtacagg gcgggcctgt
       61 gtctgaaatt cttccgaatg gcttcagagc tgtattgccg gctgacacca ccgttaacgt
      121 tgacatcaaa aaagatggaa ccgcgatagc tgatttctct aatgagttca aaaattataa
      181 gaaagaagac gaacagaaaa tcgttcaatc tgtgacgtgg acgctgacgc aatttagttc
      241 gatagataaa gtgaagctga gaataaacgg gcatgaactg aaggagatgc ctgtaggagg
      301 gacgccgatc tcagatgatt taagccgcaa agacggcatt aatttggaaa cagccggtgt
      361 aaatgatctc actgctaccc atccgctgac agtctactat ttggcggaaa atgaagacag
      421 tgaatactac gtgccggtga ccaaacgaat cgacaattcg gaaaaagacg acgttacggc
      481 agccatcaat gaattggcta aaggtccaag caaggtgagc gggctgttaa cagacttcag
      541 tgaagatgta aagctggtca gcaaaccaaa aatcaaagac gggcgcgtga cgttggattt
      601 caatcaatct atattcggca gcgccgatga gaagacgaaa atgatttctt cagaagtgct
      661 gaacagcatt gtgctcacgt taacggagca gccggatata aaaggcgtgt ctgttaaagt
      721 gaacggaaaa tcagagctgg taaatgaaaa aggcgaaaag ctcacagaac cggtctccag
      781 accatctcaa gtgaatacgg gtagttttta aattgggatt tttgatatac tagaaagaaa
      841 gaggttagcg ttccggctgc ctctttcttt attcaattcc gggacaaaaa tggtttatgt
      901 acatacaatc ggaggtaaaa catgagacat gacggaagac aacacgatga gctgcgtcca
      961 atcacattcg atttggattt tatcagccat ccggaaggtt ctgttctaat aacagcggga
     1021 aatacaaagg taatctgcaa cgcgtctgtt gaggaccgcg taccgccgtt tttgcggggc
     1081 ggagggaaag gctggattac agcagagtac agcatgctgc cgcgggcaac aaaccaaaga
     1141 acaatcagag aatcttctaa ggggaaaatt tccggcagaa caatggagat ccaacgcctg
     1201 atcggccgcg cgcttcgagc tgttgtagat ctggaaaagc tcggtgaacg gacgatttgg
     1261 attgactgtg atgtcattca agctgatgga ggaactagaa cagcttccat tacaggcgca
     1321 tttcttgcta tggcgattgc gattggcaag ctgatcaaag caggaacaat caagacaaat
     1381 ccgatcactg attttcttgc tgcaatctct gttggaattg ataaggaaca gggaattttg
     1441 ttagatttaa attatgaaga agattcctct gctgaagttg acatgaatgt catcatgaca
     1501 ggcagcggcc gttttgtgga attgcaggga accggggaag aggcaacttt ttctagagag
     1561 gatctgaacg gtcttctggg tcttgcggaa aaaggaatcc aagagctgat tgacaagcaa
     1621 aaagaagtgc tgggtgattc tctgccagaa ctgaaataaa gacagaaagg cttgatcatc
     1681 atgaaagaag caattattgc aacacataat ccgggaaaag tgaaggaatt caaagaaatt
     1741 cttgagccaa gaggctatga tgtcaaatct ttagctgaaa ttggattcac agaggaaatt
     1801 gaagaaacag gccatacatt tgaagaaaat gccattctga aagcggaagc tgttgccaaa
     1861 gcagtgaaca aaatggtgat tgcggatgac tccggactat ccatcgataa tcttggcggc
     1921 agacccgggg tttattcagc ccgctatgca ggggaacaga aagacgacca ggcaaatatc
     1981 gaaaaagtgc tcagcgagct gaaaggtatc gaaaaagaac agcgcaccgc ccgtttccgc
     2041 tgcgcactgg ccgtgagtat tcccggagag gaaacaaaaa cagtcgaagg ccatgttgaa
     2101 gggtatattg ctgaagaacc gagaggagaa tatggctttg gctatgaccc aatttttatc
     2161 gtgaaagata aagataagac aatggctgaa ctgacaagtg atgaaaaaaa taaaatcagc
     2221 catagggctg acgcgcttaa aaagctgtct aagcttttgg aggcataagg aggaagcttg
     2281 tacatgaacg tgctgattat cagtgacagc catgggcttg aagaagaact ccaaaccatt
     2341 gcgaaacggc atgaggcaga agttgatctc atgattcatt gcggggactc tgagcttgag
     2401 acgaggcatc ctgcattgga gccttatgcg gttgtaaaag gcaattgcga ttttgccggc
     2461 gattttaagg acgagcttct tctgactgcc ggctcaagaa aaatactagt cacacacggc
     2521 caccttcacg gtataaaaca gaccttgtta aacgtatact atcgtgcaga ggagctcggg
     2581 gcggatgtta tctgcttcgg gcattcgcac atcgcgggaa gcgaagtgct gcgcggaaaa
     2641 ctgatgatta acccaggcag catccggctt ccgagggtgc gcaggacaga aagctatgct
     2701 atactgacat tagaaaatga tgctgcgaca gtccgttttt acgaccaagc aggcaatgaa
     2761 attgaggatc tgcaaaatcg agtcacacta tgaaaatgtc atgaggaaga aaattttctt
     2821 cctcatgaaa aaaattctaa aaaaccgttg acttattatt gcatcccata tataataaat
     2881 cttgtcgctg atagttaaag cgaaaaacaa aaaaacaaaa cgtgtcccag tagctcagct
     2941 ggatagagca acggccttct aagccgtcgg tcgggagttc gaatctctcc tgggacgtac
     3001 caaaagaaaa acctcaaatc catttaggat ttgaggtttt ttgttgtcgg tctatgattt
     3061 ttatttatta tttaacggat catcatcatc caagccgtca acttttcctt ctttattcag
     3121 acgaggttct tcttttttca cagtttcaga aatatgttca ttttcttcaa cagtgcgttt
     3181 gccgacaacc acttcatcag tgacaaccgg ttttttagtc acttcaagct tttcctcaac
     3241 gattggaact ctgatctctt ccgaatcgtt gacgggagca gcgtccgttt tattttcatc
     3301 cactggacgg cgttcgacat aaatttcatc atgtctcaca ggaatgtcca tatctctttt
     3361 ttctgttttc acttcttttc ctatttctac ttcgccggtt tgaacgtctt ccttatcgac
     3421 cttcagctgt tcttctcgga gcggcatcgt tttttcttct tttgttgtat agtccaattc
     3481 atttgtgcct gaaaagccgc ttgaaagggc attgccgtta tcaacaggag caattacatc
     3541 tgcatctgta tcgacggcta ccaaaagttt tccgtcatcc aaatcttctt gatacttgtc
     3601 tatttcatca gttttaatat ccaagtcgga taatgctttg ctgtgtgtag cagtatcatc
     3661 cattgtgaaa taatctttca gtttatcgaa aaaagattca gattcgtcct gatgtgcatc
     3721 gatggcttga ttgacttctg ttcctgtacg tgactccaaa taatctgtat ctcgccggct
     3781 tgtcacaaca gaaatgtcat cagaatcata gccttttgtg agtaagcctt caatcgctgc
     3841 gatggtttcc tgcggagttt catatacacc aactatgctt ttcatatcaa tctcctcctt
     3901 tatgaatttg catgatatcg ttcatgtcgt ttgtaattcc cgctgttctt tgaattaaac
     3961 aaaattgaaa acattggcgt gtatcataaa ggtgaaaaat gtgtgaaaat aaaaaaagat
     4021 agataagaca gaccttcccc tgcacttatc tatccttata aaatcgtctc acaattcctt
     4081 cttcataaac acactgtttg gatcttcatc gtagtctgca aacggttcac aatactggaa
     4141 accgaagctt tcatacaatt ttcttgccgg ctcaaatgaa gccattgaac ccgtttctaa
     4201 gcttagtcgc tcatagcctc gcttctcggc ttcttcaatg atatgctgga gaacttgttt
     4261 ggcaacgcct tttcttaaat gtgatgcaga tgttcgcatt gatttgactt ctccgtgcca
     4321 gctgtccagt tcttttagcg ctccgcaacc ggctagttca tcaccctccc atgcactcca
     4381 aaatgttatt ccagggcctc ttagtttctc taaacctaag gcatggatgc tttccggcgg
     4441 ggacataagc gtcatgctag taaatgctca ttcaccagtg aaaccacctg atgtccagtt
     4501 aaatcatcta tttttatatg cattttattc ctcctcaaac attcatctta atcatattcc
     4561 atcctgtttc caactataaa gacagaaaat ctgacagtat tgaagcactt ttggaatgta
     4621 tgagttgcaa aagatgcttg aaagcaacaa agaggccgaa atcgtgttcg gcccttgcag
     4681 ttttctttaa tatctaaagc ctccatgcac accggctgtt ccgctaaaac cgccgacatg
     4741 tgtcgccgga atactgaacc cgccgctatg gccgctgaag ccagtgcctg aaaattgctg
     4801 cccgaaaaaa tctgaagtgt atggataaga ggagtacata gcagagggag tggttaacgg
     4861 gctatatgcc tggctgaacg gctgtccgta tccgtagcct ccaaatggct gatggctttg
     4921 ctggtaaaag ggagggacag caggataata ctgctgcgga aagctcggga agcttggaaa
     4981 gcctgcaggg aatccttgca tgtctgctaa tgatttattc atcgtatcac cttttctttg
     5041 caagatacca ttaatgtatg ccggggaata atagtggtgc ctatccgaac ttgaaatgga
     5101 ttgcaagttg atctgtcaga ctcaatccat atacgaacca tagcgtgtta taaaatctta
     5161 catgtttata taaaattaaa taattctggt gtattcttga tagattaata aaaaaattat
     5221 aaaaactttt aacatttgca attccttttg taccaataat gaaagcgtat acaatataga
     5281 ttgattaatc aaaattgtct aataatttta aaaaatgctg ttgacactgc gtccaaagcg
     5341 gcgtaatatg agttcaacaa aagataaacg caagcttcac aagcgaaaat catcgcagta
     5401 tgattctaaa aaaatgaaaa acaaacgacc ttcttgaaca gctggaaagc cgttctgaag
     5461 ggtgaatatg aaaagcgcag atgaggataa gtagccttga taaagctttc cacagagaac
     5521 cgggttagct gagaaccggt gaagctttac aaggtgaact cgcctcagag tgccagtctg
     5581 aaatgacagt aggacttggc cgggtgaact tgattcactc gttactaaag cggatagaaa
     5641 tatccatgag acggccgact aaggccgtaa acaagggtgg taccgcggaa agaaaagcct
     5701 tttcgcccct tttagctatc gcagttactg cgcggctgat tgtgggtgga agggcttttt
     5761 ttattgaata atcagctatc tagctaataa aaagatgatc tttaaaggat gaaaatccaa
     5821 aaggaggaac taaaatgagg actaatgtac aggtggattc agcatctgcc aaatgtacac
     5881 agacgatgag cggagcatta atgctgattg aatcattaaa aaaagagaaa gtagaaatga
     5941 ttttcggtta tccgggcggg gctgtgcttc cgatttacga taagctatac aattcagggt
     6001 tggtacatat ccttccccgt cacgaacaag gagcaattca tgcagcggag ggatacgcaa
     6061 gggtctccgg aaaaccgggt gtcgtcattg ccacgtcagg gccgggagcg acaaaccttg
     6121 ttacaggcct tgctgatgcc atgattgatt cattgccgtt agttgtcttt acagggcagg
     6181 tagcaacctc tgtaatcggg agcgatgcat ttcaggaagc agacatttta gggattacga
     6241 tgccagtaac aaaacacagc taccaggttc gccagccgga agatctgccg cgcatcatta
     6301 aagaagcgtt ccatattgca acaactggaa gacccggacc tgtattgatt gatattccga
     6361 aagatgtagc aacaattgaa ggagaattca gctacgatca tgagatgaat ctcccgggat
     6421 accagccgac aacagagccg aattatttgc agatccgcaa gcttgtggaa gccgtgagca
     6481 gtgcgaaaaa accggtgatc ctggcgggtg cgggcgtatt gcacggaaaa gcgtcagaag
     6541 aattaaaaaa ttatgctgaa cagcagcaaa tccctgtggc acacaccctt ttggggctcg
     6601 gaggcttccc ggctgaccat ccgcttttcc tagggatggc gggaatgcac ggtacttata
     6661 cagccaatat ggctcttcat gaatgtgatc tattaatcag tatcggcgcc cgttttgatg
     6721 accgtgtcac aggaaacctg aaacactttg ccagaaacgc aaagatagcc cacatcgata
     6781 ttgatccagc tgaaatcgga aaaatcatga aaacacagat tcctgtagtc ggagacagca
     6841 aaattgtcct gcaggagctg atcaaacaag acggcaaaca aagcgattca agcgaatgga
     6901 aaaaacagct cgccgaatgg aaagaagagt atccgctctg gtatgtagat aatgaagaag
     6961 aaggttttaa acctcagaaa ttgattgaat atattcatca atttacaaaa ggagaggcca
     7021 ttgtcgcaac agatgtaggc cagcatcaaa tgtggtcagc gcaattttat ccgttccaaa
     7081 aagcagataa atgggtcacg tcaggcggac ttggaacgat gggattcggt cttccggcgg
     7141 cgatcggcgc acagctggcc gaaaaagatg ctactgttgt cgcggttgtc ggagacggcg
     7201 gattccaaat gacgcttcaa gaactcgatg ttattcgcga attaaatctt ccggtcaagg
     7261 tagtgatttt aaataacgct tgtctcggaa tggtcagaca gtggcaggaa attttctatg
     7321 aagaacgtta ttcagaatct aaattcgctt ctcagcctga cttcgtcaaa ttgtccgaag
     7381 catacggcat taaaggcatc agaatttcat cagaagcgga agcaaaggta aagctggaag
     7441 aggcattaac atcaagagaa cctgttgtca ttgacgtgcg ggttgccagc gaagaaaaag
     7501 tattcccgat ggtggctccg gggaaagggc tgcatgaaat ggtgggggtg aaaccttgaa
     7561 aagaattatc acattgactg tggtgaaccg ctccggggtg ttaaaccgga tcaccggtct
     7621 attcacaaaa aggcattaca acattgaaag cattacagtt ggacacacag aaacagccgg
     7681 cgtttccaga atcaccttcg tcgttcatgt tgaaggagaa aatgatgttg aacagttaac
     7741 gaaacagctc aacaaacaga ttgatgtact gaaagtcaca gacatcacaa atcaatcgat
     7801 tgtccagagg gagctggcct taatcaaggt tgtctccgca ccttcaacga gaacagagat
     7861 taatggaatc atagaaccgt ttagagcctc tgtcgttgat gtcagcagag acagcatcgt
     7921 tgttcaggtg acaggcgaat ctaacaaaat tgaagcgctt attgaattgt tgaaacctta
     7981 tggcattaaa gaaatcgcga gaacaggtac aacggctttt gcgaggggta cccagcaaaa
     8041 ggcgtcatcc aataaaacaa tatctattgt ataaaacata acaagggaga gattgaaatg
     8101 gtaaaagtat attataacgg tgatatcaaa gagaacgtat tggcaggcaa aacagtagcg
     8161 gttatcggat acggttcgca aggccacgca catgccctga accttaaaga aagcggagta
     8221 gacgtgatcg tcggtgttag acaaggaaaa tctttcacgc aagcccaaga agacggacat
     8281 aaagtttttt cagtaaaaga agcggcagcc caagctgaaa tcatcatggt tctgcttcct
     8341 gatgaacagc agcaaaaagt atacgaagct gaaatcaaag atgaattgac agcaggaaaa
     8401 tcattagtat ttgctcacgg atttaacgtg catttccatc aaattgttcc tccggcggat
     8461 gttgatgtat tcttggtagc gcctaaaggt ccgggacact tggtcagaag aacatatgag
     8521 caaggagccg gcgtacctgc attgttcgca atctatcaag atgtgactgg agaagcaaga
     8581 gacaaagctc tcgcatatgc aaaaggaatc ggtggcgcaa gagcgggagt attagaaacg
     8641 acatttaaag aagaaacaga aacagatttg ttcggtgagc aagcggttct ttgcggcgga
     8701 ttaagcgcgc ttgtcaaagc aggatttgaa acattaactg aagcaggtta tcagcctgaa
     8761 cttgcatact tcgagtgtct gcatgagctg aaattaatcg tagaccttat gtacgaagaa
     8821 ggacttgcag gaatgagata ttcaatttct gacacagcac agtggggaga tttcgtatca
     8881 ggccctcgcg ttgtggatgc taaagtaaaa gaatcgatga aagaagtatt aaaagatatc
     8941 caaaacggta cattcgcaaa agaatggatc gtcgaaaacc aagtaaaccg tcctcgtttc
     9001 aacgctatca atgcgagcga gaacgaacat caaatcgaag tagtgggaag aaagcttcgt
     9061 gaaatgatgc cgtttgtgaa acaaggcaag aagaaggaag cggtggtctc cgttgcgcaa
     9121 aattaatttt ttcgatacga cgcttcgtga tggtgaacag tcccctggag tgaacttgaa
     9181 tacacaggag aaacttgcca tagctaagca gctcgaaaga ctcggggcag atatcattga
     9241 agcgggattt cccgcttcgt cccgaggtga ctttttagct gttcaggaaa tcgctagaac
     9301 cattaaaaat tgttcagtga ctggtctggc ccgttgtgta aaaggtgata ttgatgctgc
     9361 ttgggaagcg ttaaaggatg gtgcttaccc gagaattcat gtttttatcg ccacatcgga
     9421 cattcatttg aaacacaagc tgaaaatgac acgtgagcaa gtcattgaaa gagcagttga
     9481 aatggtgaca tacgcaaaag aacgttttcc ggttgtgcaa tggtcagctg aagatgcctg
     9541 ccgcactgag ctgccgtttc tggcagaaat cgtcgagaaa gtgattgacg caggcgccag
     9601 tgttatcaat cttccagaca ctgtcggcta cctggctcca gcggaatacg gaaatatctt
     9661 taaatatatg aaggaaaacg ttccgaacat tcacaaagca aagctttcag cccactgtca
     9721 tgatgattta ggaatggcag ttgcaaactc tcttgctgcg attgaaaatg gcgctgatca
     9781 aatcgaatgc gctgtgaacg ggatcggtga aagagccgga aacgcggcat tagaggaaat
     9841 tgccgtagcc ctccatacca gaaaagattt ctaccaagtc gaaacaggca ttacactgaa
     9901 cgagattaag agaacaagtg atttagtaag caaactgaca ggcatggctg tcccacgcaa
     9961 caaagcggtt gttggagata atgcatttgc tcatgaatca ggcatccatc aggacggctt
    10021 tttaaaggaa aaatcgactt atgaaattat ttcaccggag cttgtcggcg taaccgcaga
    10081 tgcgcttgtc ctaggtaaac attccggacg ccacgcattt aaagaccggc tgactgcttt
    10141 aggattccaa tttgacagtg aagagattaa taaattcttt acgatgttca aagagttgac
    10201 tgagaagaaa aaagaaatca ctgatgagga tcttgtttct cttattttag aagaaaaagt
    10261 aacagatcgc aagattgggt atgaatttct ttctctgcaa gtacattacg gaacaagtca
    10321 ggtccctacg gctactcttt cgttgaaaaa tcaagaaaat gcagagctta ttcaggaagc
    10381 tgcaactgga gctggaagtg tggaagcaat ctacaatacg cttgagcgct gcatcgataa
    10441 ggacgtggag cttttagact accgcattca gtctaacaga aaaggcgaag atgcatttgc
    10501 ccaggtgtat gtaagagttt tggtgaacgg aaaagaatca gcaggtcggg gcatagcgca
    10561 agacgtatta gaagcatcag cgaaagccta tttgaacgca gtcaaccgtc aattggtttt
    10621 ccagtcgaat atgagcggat tgaaaaacca cacagctgtc ggatcataaa agaaaggaga
    10681 acggttaact tgaagaaacg tattgctcta ttgcccggag acgggatcgg ccctgaagta
    10741 ttagaatcag cgacagacgt actgaaaagt gttgccgaac gctttaacca tgaatttgaa
    10801 tttgaatatg gcctgattgg aggggcggct attgatgaac atcataaccc cctcccggag
    10861 gaaaccgttg ctgcttgtaa aaatgcagac gcgatattgc ttggtgctgt cggcggaccg
    10921 aaatgggatc aaaatccttc ggaactgaga ccggaaaaag ggctgctcag catcagaaaa
    10981 cagcttgatt tgtttgcgaa tttacggcct gtgaagg
//
