LOCUS       gnlProkkaMDKIOEFL_2    21612 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MDKIOEFL_2.
ACCESSION   gnlProkkaMDKIOEFL_2
VERSION     gnlProkkaMDKIOEFL_2
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 23:32:13
            Original ID  :: gnl|Prokka|MDKIOEFL_2
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 373220
            Orig. end    :: 394832
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21612
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11612]"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11612
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     cand_cluster    1..21612
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /kind="single"
                     /product="sactipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21612
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="sactipeptide"
                     /region_number="3"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /tool="antismash"
     CDS             complement(421..540)
                     /locus_tag="ctg2_382"
                     /transl_table=11
                     /translation="MKLKSKLLLFCLALSTVFVATTIANAPTHQIEVAQRGMI"
     CDS             complement(524..1669)
                     /locus_tag="ctg2_383"
                     /transl_table=11
                     /translation="MTGVISSSSIGEKINEWYMYIRRFSIPDAEYLRREIKQELDQMEE
                     DQDLHLYYSLMEFRHNLMLEYLEPLEKMRIEEQPRLSDLLLEIDKKQARLTGLLEYYFN
                     FFRGMYELDQREYLSAIKFFKKAESKLIFVKDRIEKAEFFFKMSESYYYMKQTYFSMDY
                     ARQAYEIYKENEAYNIRLLQCHSLFATNFLDLKQYEDAISHFQKAYSMAEAEKQPQLMG
                     RTLYNIGLCKNSQSQYEDAIPYFKRAIAVFEESNILPSLPQAYFLITQIHYKLGKMDKA
                     HEYHSKGMAYSQKAGDVIYLSEFEFLKSLYLSGPDEEAIQGFFNFLESKMLYADLEDFA
                     IDVAKYYHERKNFQKASAYFLKVEQVRQLIQGGVSLYEIEV"
     CDS             1899..3254
                     /locus_tag="ctg2_384"
                     /transl_table=11
                     /translation="MRKNKLSFKEKAGAEQEECLCFCEGEASREAMFQAPIELPEGFVV
                     DPAEAVANVTWNADSLSCVSDRCLIQTGPEPDEVGVQFAVRLQGTVTLLVSVSPVRNQY
                     GQGDGAVSVIHNAEIDQVVYYSDEPDDCPDISDITIENLVVVPPFYGSPLSVTGTIVLV
                     PEPEPVYAFTANPNDQSVSVIDTNTHTVVTTIALPYNPAGIEITPDKSAVFVLHPNNNV
                     ISVIDYDTLTVTATILLDQPPRLIRFIPNHEFAYVFTGTAIYVIGIDTLTVERSIPVEG
                     FDIAIDPNGLFAYVLNFGLVQKVDLSTGEVLGTIERELIVSSIETDSTERYAYVLEQEF
                     LFNYLTVIDLNTFTIRDTQELEPDGLYVMFTSGSEVYLHDSFTGNLYSVSPNGAGVIGN
                     LPQSATDYAFTPNGDFLYATRFIEQSIIVYNTDDYSEETVISLGVSPGAITI"
     CDS             3293..4669
                     /locus_tag="ctg2_385"
                     /transl_table=11
                     /translation="MKKNDLSALQENCFCFCDEEISREAPFQVPIDFPEGFKVDTAEAS
                     AAVTWSTDNLSCISEPCLIQTGPEPEDIGVRYAVRVQGTITLLVSVSPVRNQYGQGNGA
                     VSVIHTEEIDQVVYYAAQSDRCPDFSQMTVEDLLIVPPFYGSPLTVTGTLVLPPSPDPQ
                     SYVFTANTGDSTVSVIDADLNTVVKTIPFSDVPTNLGVTFDKAFTYVLHGNTNLVSVID
                     NKTLTIINTITVGGGPRKIEFDPTDEFAYVMAAGSIYVINTASQSVIDVIPIPGALDFA
                     LDPNGQYVYTANGSSWSVDKYDANTGQLVESIIDSFEFPSLIATPYAGNFAYVLNGELW
                     PKGVTEISLSPLSRGGDFSRLFETLRTIVFSLDSTRAYFLEPYSEPFLINNLYVVNTAR
                     QRIIANVSLPGAFDLAVTPDKQYIYAAQPNDNAVTVYRTSDYTAVTVIPVGAGPSAIAM
                     "
     CDS             complement(4675..5376)
                     /locus_tag="ctg2_386"
                     /transl_table=11
                     /translation="MKKNTVFTLLLLLIGMAAYSFGWVQAVAEAAAQYVQMINNDAVRL
                     GLLACTAALLMLPAFLYLHYVTQSVKNMTAAFQKLTQSHQSCCEFQQHNLCSRYAEDVK
                     SLRDSYKNVRQTYVMAAVLCQVIIFGCMFEIVKAVPFRLHTPPALSMGLAMLLILYLLF
                     CMRTYLRQLFRHGSLFRKVFAGALAAAGIWWMLSFSISELLFLIILATIQQIGSFIYKR
                     FSYRSTASLDL"
     CDS             complement(5373..6653)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_387"
                     /sec_met_domain="Peptidase_M16 (E-value: 6.1e-14, bitscore:
                     48.3, seeds: 24, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKKAFFQQLDERTDIRYTDSGLKIFRLKFPRTHLRLCNLKIDFG
                     SRDVCIRAESGDTLLPYGTAHFLEHLLFWHNGRNLYSDFFAHGALLNAFTTYTDTNFMF
                     TSLPDRLRQTIPILLDALWNHSFDKKIVAQEKAVITSEIQTAHLNHQLSYHYQLISMLS
                     PSSPAAVFPAGRIEDIEALDINDLQKAYKAAYQAHRMTLFLIGGSENTETLLPPHLQLE
                     KRPDYHAERKIIPACPPALSQKMVLGDEERMEDTWTGLQIGALPGQNDLLSIKLYWDIA
                     ARILFQLDSPFFQEIQQTYRLEIDRLSAETYIYEDGGFLILHSQGTHSSAYIDVASYYV
                     TQKKEQVAAWLQYGKDSLTDAIIYDSDYVRKCFEWAAECDRCDCSFLDMYHIIQDMDAQ
                     VFLSLIDAIASSNKAIIHISQKEAIRQ"
     CDS             complement(6658..7842)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_388"
                     /sec_met_domain="Peptidase_M16_C (E-value: 1.3e-05,
                     bitscore: 21.3, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIQAKENGLEVNLLKTHQFSTISIAASFLKPIESAAEPEEETIYF
                     YGAAAYLKEQIIDAFGCAAGSRFMYSANLFFDQQLKTCGTRLIHPLYNGNLHVDALLKT
                     FADLSFPSSLSFEAVEKARNELLLRIEKKFTDPFSYSAARLAEEVFGNPMYGTGMFGRR
                     DRIKAIHPKRFLDATDFIVDLVSQQKQLNILGQVQACDVRGHAPQTSAVTSGRIPVNRH
                     VFETETRSAAGPSVLTLGFDCGEMKDASDYIKIQLIDGLLGKYGHSALFKHFREKDLAV
                     YHVITRYDVMNNLLLVSICTDQLHEIDIPPRVLEAVSAFHTDERELEQAKQFLRNELLL
                     QFDSPEGLLAYMGILRRFSCTKEALLDGISAVTCRDVLQFIATINYIGAHVVRG"
     CDS             complement(7808..9118)
                     /locus_tag="ctg2_389"
                     /transl_table=11
                     /translation="MNNIIPIMSLLFKQLYSRQGKKDAIRIAAGLVILAVFEIGLIRQA
                     GIDESVLRKTYIILALLLMNTYMVFLSVTSQWKESYMKLSCLLPISSRSFWLAQSVVLF
                     VDTCLRRTLFFFILPLFLFGNGTLSGAQTLFWLGRFSFFTVYSIIFGVVLSNHFVKKKN
                     LMFLLHAAIFACVCLCAALMPAATLPLCAVHMLWAVIIDFPVFLQAPPQQGKMHSFMRR
                     SEFSFYKREWNRFISSKAMLLNYAVMAVFSGFFSFQMMNTGIFNQQVIYIVISALLLIC
                     SPIALLYSIEKNDRMLLITLPIKRKMMFWAKYRFYSGLLAGGFLLVVMIVGFISGRPIS
                     VLTFLQCIELLLAGAFIRLTADEKRPSFSWQTEQQLWSGFSKYRSYLFCLPLFLATLAG
                     TAVSLAVIPIAGLVIVYYLQKQEGGFFDTSKRERLGS"
     CDS             complement(9111..9830)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 127; E-value:
                     1.6e-38)"
                     /gene_kind="transport"
                     /locus_tag="ctg2_390"
                     /transl_table=11
                     /translation="MSILDIHDVSVWYERDNVILEQVDLHLEKGAVYGLLGVNGAGKTT
                     LINTLTGVNRNFSGRFTLCGIEAEAGMPQKTSDQLKTHRYFAADYPLLFTEITTKDYVS
                     FVHSLYQKDFSEQQFASLAEAFHFSKYINRRISELSLGNRQKVVLMTGLLLRAPLFILD
                     EPLVGLDVESIEVFYQKMREYCEAGGTILFSSHLLDVVQRFCDYAAILHNKQIQKVIPI
                     GEETDLRREFFEVIGHE"
     CDS             complement(9827..9988)
                     /locus_tag="ctg2_391"
                     /transl_table=11
                     /translation="MSPAQRRILLYILSFIFVIGAVVYFVKSDYLFTLIFIAIAILFGM
                     RARKADSR"
     CDS             complement(10001..11332)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: subtilosin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Subtilosin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_392"
                     /sec_met_domain="subtilosin (E-value: 0.0, bitscore:
                     1072.2, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="Subtilosin_rSAM_RRE (E-value: 1.3e-29,
                     bitscore: 98.5, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 8.3e-08, bitscore: 28.5,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.3e-22, bitscore: 76.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 1.3e-10, bitscore:
                     37.5, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 4.1e-10, bitscore: 36.1,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDLNKTAYE
                     LCMRMDGQKTAEQILAEQCAVYDESPEDHKDWYYDMLNMLQNKQVIQLGNRASRHTITT
                     SGSNEFPMPLHATFELTHRCNLKCAHCYLESSPEALGTVSIEQFKKTADMLFDNGVLTC
                     EITGGEIFVHPNANEILDYVCKKFKKVAVLTNGTLMRKESLELLKAYKQKIIVGISLDS
                     VNSEVHDSFRGRKGSFAQTCKTIKLLSDHGIFVRVAMSVFEKNMWEIHDMAQKVRDLGA
                     KAFSYNWVDDFGRGRDIVHPTKDAEQHRKFMEYEQNVIDEFKDLIPIIPYERKRAANCG
                     AGWKSIVISPFGEVRPCALFPKEFSLGNIFHDSYESIFNSPLVHKLWQAQAPRFSEHCM
                     KDKCPFSGYCGGCYLKGLNSNKYHRKNICSWAKNEQLEDVVQLI"
     CDS             complement(11481..11612)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: Subtilosin_A"
                     /gene_functions="biosynthetic-additional (sactipeptides)
                     predicted sactipeptide"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_393"
                     /sec_met_domain="Subtilosin_A (E-value: 2.3e-29, bitscore:
                     97.4, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKAVIVENKGCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
     CDS_motif       complement(11583..11612)
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MKKAVIVENK"
                     /locus_tag="ctg2_393_sactipeptide"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       complement(11481..11582)
                     /prepeptide="core"
                     /locus_tag="ctg2_393_sactipeptide"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="33.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKAVIVENK"
                     /leader_location="[11582:11612](-)"
     CDS             11925..12353
                     /locus_tag="ctg2_394"
                     /transl_table=11
                     /translation="MKQETPITLHVKSVIEDDGNQEVIEFRTTGFYYVKQNKVYLSYYE
                     EHDLGKVKTIVKVSEGEVLVMRSGAVKMNQRFVTGASTIAKYKMSFGELELKTSTKSIQ
                     SDLDEEKGRISIAYDMHVGDEQEHLHNMTITYEGGTHA"
     CDS             12350..14020
                     /locus_tag="ctg2_395"
                     /transl_table=11
                     /translation="MNIAEQMKDVLKEEIKAAVLKAGLAEESQIPNVVLETPKDKTHGD
                     YSTNMAMQLARVAKKAPRQIAEEIVAHFDKGKASIEKLDIAGPGFINFYMNNQYLTKLI
                     PSVLEAGEAYGETNIGNGERVQVEFVSANPTGDLHLGHARGAAVGDSLCNVLSKAGYDV
                     SREYYINDAGNQINNLALSVEVRYFEALGLEKPMPEDGYRGEDIIAIGKRLAEEYGDRF
                     VNEEESERLAFFREYGLKYELEKLRKDLENFRVPFDVWYSETSLYQNGKIDKALEALRE
                     KGHVYEEDGATWFRSTTFGDDKDRVLIKKDGTYTYLLPDIAYHKDKLDRGFDKLINVWG
                     ADHHGYIPRMKAAIEALGYEKGTLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIEE
                     VGLDAVRYFFAMRSADTHMDFDLDLAVSTSNENPVYYAQYAHARICSMLRQGEEQGLKP
                     AADLDFSHIQSEKEYDLLKTIGGFPEAVAEAAEKRIPHRVTNYIYDLASALHSFYNAEK
                     VIDPENEEKSRARLALMKATQITLNNALQLIGVSAPEKM"
     CDS             14114..15343
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 105.5; E-value: 4.2e-32)"
                     /gene_kind="transport"
                     /locus_tag="ctg2_396"
                     /transl_table=11
                     /translation="MIRLIIESLKGASQMINRQHIQLSLQSLSLVAGFMVWVLISSLIS
                     QITLDIHLSKGEISLVTAIPVILGSLLRIPLGYLTNRFGARLMFMVSFILLLFPVFWIS
                     IADSLFDLIAGGFFLGIGGAVFSIGVTSLPKYYPKEKHGVVNGIYGAGNIGTAVTTFAA
                     PVIAQAVGWKSTVQMYLVLLAVFALLHVLFGDRHEKKVKVSVKTQIKAVYRNHVLWFLS
                     LFYFITFGAFVAFTIYLPNFLVEHFGLNPADAGLRTAGFIAVSTLLRPAGGFLADKMSP
                     LRILMFVFAGLTLSGIILSFSPTIGLYTFGSLTVAVCSGIGNGTVFKLVPFYFSKQAGI
                     ANGIVSAMGGLGGFFPPLILASVFQATGQYAIGFMALSEVALASFVLVIWMYWQERMKT
                     HTERNSQSIN"
     CDS             15442..16158
                     /gene_functions="regulatory (smcogs)
                     SMCOG1133:Transcription regulator, crp (Score: 123.5;
                     E-value: 1.2e-37)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg2_397"
                     /transl_table=11
                     /translation="MNFLSVRPSDSDLISSDLHELLESISTKRKMEKHTYLFREGMDAE
                     ELYLIQSGLIEIGKLTSDGKDLTLRICQKHDIVGELTLFTEEPRYMLSAKVLEDGEVLV
                     INKNKLEKELIQNGALTFEFMKWMSTHLRKIQSKIRDLLLHGKKGALYSTLIRLSNSYG
                     VERSDGILINIVLTNQDLAKFCAAARESINRMLGDLRKKGVISIDESGKIILHKRDYLR
                     CEIECENCPLEICNID"
     CDS             complement(16191..16910)
                     /locus_tag="ctg2_398"
                     /transl_table=11
                     /translation="MKALIPKQHGAWAMLLIPFLLGMAKGGPVIWHIPLFLGWLFLYLA
                     VYPVTLALKKKQSKPYQKWMCYYGFPACCFLMISVFHKPPLIWVGVSLLPLFLIHMYFA
                     RRKNERALLNDVAGVLFFCSGGFASCWLGMGTLDGWAWFIFLQSALFFIGSSFYVKSVI
                     RERKNRTFAYWSWGYHLLLPFLSALFGAGWAFLAFIPSSLRAWFFHGRDWPVKTIGILE
                     ILNACFFLAVMCLFITR"
     CDS             17054..17530
                     /locus_tag="ctg2_399"
                     /transl_table=11
                     /translation="MNQCDYLLFLKQLPMFNEVPLSIVETLLKNGTFIRGSCDQSPSFL
                     HSQSVYIVLKGSVRFVDSRLPEGSKTVALWEKGDVFPIDEKGGLYLSPFISVNATSDIL
                     ILNIPYYIFKKMMSYHPQLQMNFLAMLQQNVFCSYQLFLRYLHTSQDENAEPGS"
     CDS             17749..21435
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1134:flavodoxin (Score: 80; E-value: 1.9e-24)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_400"
                     /transl_table=11
                     /translation="MKKKKRSPLFRRLNYFSPIEHHSNKHSQTTREDRDWENVYRNRWQ
                     YDKVVRSTHGVNCTGSCSWNIYVKNGIVTWEGQNLNYPSTGPDMPDFEPRGCPRGASFS
                     WYIYSPLRVKYPYVRGVLINLWREALQEHQNPLDAWKSIVENPEKAKSYKQARGKGGFV
                     RAEWPEVLKLISASLLYTVMKYGPDRNVGFSPIPAMSMISHASGSRFMSLIGGPMLSFY
                     DWYADLPPASPQIWGDQTDVPESSDWYNSGYIITWGSNVPLTRTPDAHFLAEARYKGAK
                     VISISPDFAESSKFADDWLSIRQGTDGALAMAMGHVILQEFYVNQETERFIEYAKQYTD
                     FPFLVTLSKENGVYTAGRFLHAKDIGRKTKHDQWKPAVWDEQTSSFAIPQGTMGSRWDG
                     QQKWNLHMIDEETGEPIEPRLSVLGIEDEIGTVRIPYFSNDGNKVLERDLPIKKMNLNG
                     EETYITTVFDLILANYGVNRGIGERSAVSYDDPEPFTPAWQEQMTGIKKEAVVKIAREF
                     AQNAIDTDGRSMIIVGAGINHWFNSDTIYRAVLNLVLLVGAQGVNGGGWAHYVGQEKLR
                     PAEGWQTIATAKDWEGVPKLQNGTSFFYFATDQWRYEDQPISDLASPIAASSRYKHHAD
                     YNVLAARLGWLPSYPTFNQNGIDLYKEAEKAGAETPEDVGAYVASQLQEKKLKFAIEDP
                     DNEVNFPRNLFVWRANLISSSGKGHEYFLKHLLGTTNGLMNDDSDSIRPEEIKWREQAP
                     EGKLDLLINLDFRMAGTALYSDIVLPAATWYEKHDLSSTDMHPFIHPFAPAISAPWESK
                     SDWDIFKALSKAVSDLAEEVDMEPVKEVVATPLLHDTMQELAQPFGKINDWSKGECEAI
                     PGKTMPNIQVVERDYKHIFHKMTALGPNAALKPSGTKGMSWSIADEYESLKKRLGEITS
                     DSVAKGCPNISEAKQAAEAILTLSSTSNGKVAVKAWESLENITNLKLKDLAEEREEECF
                     TFEQITAQPKTVITSPAFSGSEKGGRRYSPFTTNVEKLIPWRTLTGRQSYYVDHELMME
                     FGETMATFKPILQHRPFLSKRPDQEGKEIVLNYLTPHNKWSVHSMYFDSLPMLTLFRGG
                     PTVWMNKDDAEDTDIKDNDWIECFNRNGVVVARAVLSHRIPKGMAFMHHAQDRHINVPG
                     TKLTNNRGGTHNSPTRIHVKPTQMIGGYAQLSYGFNYYGPTGNQRDLNVVIRKLKEVDW
                     LED"
ORIGIN
        1 tcgagcagtt gtatagtcgt aagggctgta ccatctgaaa gtaaaatgca cccttgaatc
       61 gctcgtattt gcttttgcat gaaccgcctg tgtaacaccc agtgaggaaa ctgcgatccc
      121 aaacatgatg atgagtaaac taatcctttt tttgaattga actttcaaaa taaatcctcc
      181 atttttaaac tccaattgaa gtgatactga acttaagtca tatatatatt agttcaaaaa
      241 aaaggaaaag taaacatatt tttattttca tataataaaa attatcttgt ttcctatgtt
      301 tgtgggttag gtaaccaatt taaattagtt agtaataata tttagagatt caaaaaataa
      361 aacttttgtc ccgattgtgt atttaacaaa aaaacaaccg gtgaaaaccg gttgttttca
      421 ttaaatcatt cctcgttgtg caacttcaat ttggtgtgta ggtgcatttg caatagttgt
      481 tgccacgaac acagtgctta gagccagaca aaagagtaat agtttagact tcaatttcat
      541 acaaactcac tcctccttga ataagttgcc ttacttgttc caccttcaaa aaataagcag
      601 aagctttttg aaaattttta cgttcatgat aatattttgc cacatcaata gcgaaatctt
      661 caagatcagc atacaacatt ttactttcga gaaaattaaa aaatccttga attgcttctt
      721 catccgggcc tgataagtat aaagatttca aaaattcaaa ctctgataaa tatattacat
      781 ctccggcctt ttgtgaataa gccattccct tactatgata ttcatgagct ttatccattt
      841 ttcctaattt ataatggatc tgtgtaatta aaaaatacgc ttgaggtaag gaaggaagaa
      901 tatttgattc ttcaaaaaca gctattgctc ttttgaaata aggtatggca tcctcatatt
      961 ggctttggct gtttttacaa agcccgatat tgtacaaagt tcttcccatt aattggggct
     1021 gcttttcagc ttctgccata gaataagctt tttgaaaatg tgagatggca tcctcatact
     1081 gttttaaatc taaaaaattg gtggcaaata aagaatgaca ctgcagcaat cttatattat
     1141 aagcttcatt ttctttgtat atttcatatg cttgccgtgc atagtccatt gaaaaatacg
     1201 tttgtttcat atagtaataa gattcagaca tcttaaagaa aaactcagct ttctctatcc
     1261 gatccttaac gaatatcagc ttgctttcgg cctttttgaa aaatttaata gccgacagat
     1321 attcccgctg gtccagctca tacatgcctc tgaagaaatt aaaatagtac tcaagcagac
     1381 cagttaaacg agcctgtttt ttatcaatct caagcagcag atcagacagt ctcggctgtt
     1441 cctcaatcct cattttttct aacggttcaa ggtactcaag cattaggttg tgccgaaact
     1501 ccatcagtga atagtacaaa tgaaggtctt gatcttcttc catttgatcc agctcttgct
     1561 tgatttctcg tcgcaaatat tctgcatcgg gtatgctgaa tcggcgtatg tacatatacc
     1621 attcgttaat cttttctccg atggaagaag aagatatgac acctgtcacg tttgcaaatc
     1681 cctcccttca taattctata tatgtcatat tttatcatca acattcttgt gagaagcgca
     1741 aaaaaaccgc aattttttct ttcgttacac cgcatgttgg aggaaatact ttttaaaaac
     1801 cacttttacc ctcggcaatt tgtacaagca aacacattca ccttccatat tctgttgtat
     1861 ctgcgtgagc agtgtatgtc tgaaaaggaa gtgaaggtat gagaaaaaat aagctttcct
     1921 ttaaagaaaa agcaggagca gaacaagaag agtgcttatg tttttgtgag ggagaagcaa
     1981 gccgagaagc catgtttcaa gcaccgattg aattacctga agggtttgtc gttgatccgg
     2041 ctgaagctgt tgcaaacgtg acgtggaatg cagacagcct ttcttgtgtc agtgaccgtt
     2101 gcttaattca aacggggcca gagcctgatg aggtcggtgt tcaatttgca gtgcgcctgc
     2161 agggaaccgt tacgctactc gtcagtgtct cacctgtgcg aaatcaatat ggacaagggg
     2221 acggggctgt ttccgtcatt cacaatgcag aaatcgatca agtcgtctat tattccgatg
     2281 aaccggatga ttgcccggat atcagtgaca tcacgattga gaaccttgtt gttgttccgc
     2341 cgttttacgg cagtccttta tcggtgacgg ggacgattgt gcttgtaccg gagccggaac
     2401 ccgtctacgc gtttacagcg aatccaaatg atcaatcagt ttctgtgatt gatacaaaca
     2461 cccatactgt tgtgacaacg attgctcttc cgtacaatcc ggcaggtatt gaaattacgc
     2521 cagataaaag cgctgtgttt gtcttacatc ccaacaataa tgtgatttct gtcatcgatt
     2581 atgacacatt aacagtgaca gcaactatat tgctggatca gccgcctcga ttgattagat
     2641 ttatccctaa tcatgagttt gcttatgttt tcaccggtac tgccatttat gtgattggaa
     2701 ttgatacgtt gactgttgag aggtctattc ctgtagaagg ttttgatatt gcaattgacc
     2761 ccaatgggtt gttcgcctat gttcttaatt ttgggttagt gcaaaaagtg gacttatcta
     2821 ccggtgaagt cttaggaacg attgaacgag agcttatcgt atcatccata gaaacagatt
     2881 ctacggagcg gtatgcgtat gtattagaac aagaattctt attcaattat ttgacggtta
     2941 ttgatttaaa tacgtttacg atcagggata cccaagagct ggagcctgac gggctatatg
     3001 taatgtttac gagtggatca gaggtgtatt tacatgacag cttcactggc aatttatatt
     3061 ctgtcagtcc gaatggagca ggtgtaattg gaaatcttcc gcaatcagca acagactatg
     3121 cgtttacccc gaatggcgat tttctgtatg caactcgttt tatagagcag agcatcattg
     3181 tttacaacac agatgattat tctgaggaaa ctgtgatatc tcttggggtt tcaccgggtg
     3241 ccattacgat ttaaccgctg catgttgtgc atttctaaaa ggacgtgaaa tcatgaaaaa
     3301 gaatgatctt tctgctttac aggaaaattg tttctgtttt tgtgatgagg aaattagccg
     3361 ggaagcgccg tttcaagtgc cgatagattt ccctgagggc ttcaaggttg atacggccga
     3421 agcgtcagcg gctgttacat ggagtacaga caatttgtcc tgtatcagtg agccttgctt
     3481 aatccagact gggccggaac cagaagatat cggtgttcga tatgctgtga gagtacaagg
     3541 gaccattacg cttcttgtca gtgtgtcgcc tgtgcgaaat caatatggac aaggcaatgg
     3601 ggcggtttct gtgattcata ctgaagagat tgatcaagtt gtttattatg cagcacagtc
     3661 tgaccgctgt cctgatttta gtcaaatgac agtggaagat ctgctcattg taccgccttt
     3721 ctacggcagt ccgcttacgg tgaccgggac acttgtttta ccgccatcac cagaccctca
     3781 atcgtatgtg tttactgcca atactggaga cagcacggtt tcggttattg atgcagattt
     3841 aaacactgtt gtaaaaacaa tccctttttc tgacgtgcca actaatctag gcgttacttt
     3901 cgataaagca ttcacgtatg tcctccatgg aaataccaac cttgtctcag tgattgataa
     3961 taaaacatta accatcataa ataccattac tgttggagga gggccgagaa agatcgaatt
     4021 tgatccaaca gatgagttcg catacgtgat ggccgccgga tctatatatg tgattaacac
     4081 ggcctctcaa tcggtcattg atgtcattcc gatacccggc gctttagact ttgctcttga
     4141 tccgaatgga cagtatgtct ataccgctaa tggaagcagt tggtcggttg ataaatatga
     4201 tgcaaatact gggcagttgg tagaaagtat catagattca tttgaatttc ccagtttaat
     4261 tgcaactcct tacgctggaa attttgcgta cgtgttgaat ggtgagctgt ggccgaaagg
     4321 tgtaacggag attagtttgt ctccattaag caggggaggg gacttcagcc gtttatttga
     4381 aacgctgagg acgattgtat tttctctcga tagcactaga gcttattttc tagagccata
     4441 tagtgaaccg tttcttatta ataacttata tgtagttaat acggccagac agaggatcat
     4501 tgcaaacgtg tctctccccg gcgcttttga cctcgccgta acgccggaca aacagtatat
     4561 ttatgcggca cagcccaacg acaatgctgt gaccgtgtac cgcacaagtg attatacagc
     4621 cgtgacggtg attccggttg gcgcgggtcc gtctgcgatt gcgatgtagc tattttatag
     4681 atcaagagaa gcggtgctgc gataagagaa tcgtttataa ataaatgatc cgatttgctg
     4741 aatggtagcc aggataatca gaaacagcag ttcacttata gagaaactga gcatccacca
     4801 aatcccggct gctgccagcg ctcccgcaaa cacttttctg aacaggctgc cgtgccggaa
     4861 aagctgccgc aaataagttc gcatgcaaaa caataaatac agaatcagta gcatcgcaag
     4921 tcccattgaa agggcagggg gcgtgtgaag gcggaaaggg acggctttaa cgatttcgaa
     4981 catgcagccg aatatgatga cttggcacaa cacggcagcc atcacgtatg tttggcggac
     5041 gtttttatag ctgtcacgca gcgatttgac gtcttctgca tatcggctgc acaagttgtg
     5101 ttgctgaaat tcacagcagc tttgatgaga ctgtgtgagt ttctgaaaag ctgctgtcat
     5161 gtttttcacg gattgggtga cataatgaag atagagaaaa gcaggcagca tcaggagggc
     5221 agcggtacaa gccagcagcc cgagccgcac agcatcattg ttgatcatct gtacatattg
     5281 ggcggcggct tcggcaacgg cctgaaccca gccgaaggaa taagccgcca tacctataag
     5341 cagcaataaa agggtaaaga cagtgttttt tttcattgtc tgatcgcctc tttctgagaa
     5401 atgtgaatga tcgctttgtt agaagatgca attgcatcaa tgagagacaa gaaaacctgc
     5461 gcatccatat cttgaatgat gtggtacatg tcaagaaacg agcaatcgca cctgtcacac
     5521 tcggctgccc actcgaagca tttacgcaca taatcgctgt cataaatgat cgcgtctgtc
     5581 aaagagtcct tgccgtattg aagccaggcg gcaacctgtt ctttcttctg tgtgacatag
     5641 tatgaagcca catcgatata agctgaagaa tgggtccctt gactgtgaag gatcaagaaa
     5701 ccgccatcct catagatata agtctcggct gacaagcgat cgatttccag acggtacgtt
     5761 tgctgaatct cttgaaaaaa tggtgaatct aattgaaata gaatacgagc cgcgatatcc
     5821 caataaagct ttatcgacaa cagatcgttt tgcccgggaa gtgcgccgat ctgtaatccg
     5881 gtccaggtat cttccatccg ctcctcatca cccagcacca ttttttgtga gagggctgga
     5941 gggcatgccg ggatgatttt tctttcagca tgataatccg gacgcttttc cagctggagg
     6001 tgaggaggca aaagcgtttc tgtattttct gagcccccaa tcaaaaacag tgtcatccga
     6061 tgggcttggt aggcagcctt ataggctttt tgtaaatcat tgatgtccag cgcctcaata
     6121 tcttcgattc tgcctgcggg gaaaacggca gctggtgagg agggagaaag catgctgatc
     6181 agctgataat gatatgagag ctgatggtta aggtgtgctg tttgaatttc gcttgtaatc
     6241 acagcttttt cctgagcgac aatcttcttg tcaaatgagt ggttccataa agcatcaagc
     6301 aggatgggga tcgtttgtct gagccgatcc ggtaatgagg taaacatgaa attggtatcg
     6361 gtgtaggtag tgaatgcgtt taaaagcgcg ccatgcgcaa aaaaatcact gtacagattg
     6421 cggccgttat gccagaagag aagatgctct aaaaaatgtg ctgtgccata cggaagcagt
     6481 gtatcaccgg attctgcccg tatacataca tcccggcttc caaaatcgat ttttaaattg
     6541 cacagccgca ggtgggtgcg ggggaatttc aatctgaata tttttagtcc gctgtctgtg
     6601 tatctgatat cggttcgttc atccagttgt tgaaaaaagg ctttcttttc catctcttca
     6661 tccccttact acatgagctc cgatataatt gatggtcgct atgaattgca atacatcacg
     6721 gcatgtaacc gctgagatgc catccagcaa ggcttctttc gtgcaggaga agcggcgcag
     6781 gatccccata taggccaata gaccttcggg agaatcgaat tgcagcagca attcattgcg
     6841 taaaaactgc tttgcctgtt ctagttcccg ctcatctgta tgaaaagctg agacagcttc
     6901 caaaacgcgc gggggaatgt ctatctcatg aagctgatct gtacatattg aaacaagcag
     6961 caaattgttc atgacatcgt aacgggtgat aacgtgatag actgccagat ccttctctct
     7021 gaagtgcttg aataaagcgg aatggccgta ctttcccagt aatccgtcta ttagctgtat
     7081 tttgatataa tcgctggcat ctttcatctc tccgcagtca aatccgagtg tcaagacgga
     7141 aggacctgca gcgctgcgtg tctctgtttc aaaaacatgc cggtttacgg gtattcttcc
     7201 ggacgttaca gcggacgttt gcggggcatg tccccgaaca tcacatgctt gtacttgtcc
     7261 caatatgttc agctgttttt gctgggacac taaatcaacg ataaagtccg ttgcgtcgag
     7321 aaaccgttta ggatgaatcg cctttatcct gtctctccgg ccaaacatgc ctgtgccgta
     7381 catcgggttt ccgaagacct cctcagccaa gcgcgccgcc gagtaggaga aaggatcagt
     7441 gaatttcttt tcgattctca gcagcagctc attcctggcc ttttcaactg cttcgaatga
     7501 aagagaagaa gggaaagaca agtctgcaaa agttttcagc agggcgtcaa catgaagatt
     7561 cccgttatat aatgggtgaa tcaaacgggt cccgcaggtt ttcagctgct gatcaaaaaa
     7621 gagattcgct gagtacatga aacggctgcc ggcagcacaa ccaaaagcgt caatgatttg
     7681 ctccttcagg tatgcggcgg cgccgtaaaa ataaattgtt tcttcctcag gttccgccgc
     7741 gctttcgatt ggtttcagaa agctcgcggc gattgaaata gttgaaaatt gatgagtctt
     7801 cagcaggtta acttccaagc cgttctcttt tgcttgtatc aaagaaacca ccttcctgtt
     7861 tttgcaggta atagactatg accagaccgg ctatcggaat gaccgccaag gatacagcgg
     7921 tgccggctaa tgtggctaag aataggggaa gacaaaacag ataagaccga tattttgaga
     7981 aaccgctcca tagctgctgc tccgtctgcc agctgaagga gggccttttt tcatccgcag
     8041 ttaacctgat aaaagctccc gccagcagca actcaataca ctgcaaaaaa gtgagaactg
     8101 aaatcggacg gccgctgatg aaacccacaa tcatcacgac aaggagaaat ccgcctgcca
     8161 ataggcctga ataaaagcga tatttcgccc aaaacatcat tttccgcttg atcggaagcg
     8221 tgatgagcag catccggtca tttttttcaa tcgagtacaa aagggcgatc ggcgagcaga
     8281 tgagcaaaag cgcggaaatc acgatataaa tcacttgctg attgaagatg ccggtattca
     8341 tcatctggaa cgaaaagaag ccgctgaata ccgccattac cgcgtaattt aacagcatcg
     8401 ctttagaaga gataaatcgg ttccactctc ttttgtaaaa cgaaaattca gatcgccgca
     8461 taaatgaatg catcttgccc tgctgcggag gcgcctgcag aaagacagga aagtcaatga
     8521 tcaccgccca cagcatatgc accgcgcaaa gcggaagcgt ggcggccggc atcaaagcgg
     8581 cgcagagaca tacacaggcg aatatcgccg catgcagcag aaacatcaag ttcttctttt
     8641 tgacgaagtg gttgcttagc acaactccga aaataatgga gtaaacggta aaaaacgaaa
     8701 acctgccgag ccaaaacaat gtttgcgccc ctgacagcgt tccgtttcca aataagaaca
     8761 gcggtaaaat aaaaaagaat aaagttcttc tcaaacaggt atcgacaaac aaaacgacac
     8821 tctgggcgag ccaaaagctc cgtgaagaaa tcggcaggag gcagctcagt ttcatataag
     8881 attccttcca ttgagatgtc acggaaagaa acaccatata tgtgttcatc aaaagaagcg
     8941 cgagtatgat atacgttttg cgcaacaccg attcatcaat gccggcctgg cggatcagcc
     9001 cgatttcaaa cacggccaga atgacaaggc ctgcggcaat gcggatggcg tcctttttcc
     9061 cttgccggct gtaaagctgt ttgaacagca aagacatgat agggattatg ttattcatgg
     9121 ccgatcacct caaaaaattc ccgccgcaga tcggtctcct ctccaatcgg aatgaccttt
     9181 tgaatctgtt tgttgtgaag aatagccgca taatcacaaa atctttgcac gacatcgagc
     9241 agatgagaag aaaacaaaat ggtcccgcct gcttcacagt actcgcgcat tttctgataa
     9301 aaaacctcta tcgattccac atccaaaccg acgagcggct catccaaaat aaacagggga
     9361 gcgcgcagca ataagcctgt catcaataca accttttgcc tgttccccaa ggacagctcc
     9421 gaaattctcc tgttgatgta tttcgaaaaa tgaaaggcct cggccaaact ggcaaactgc
     9481 tgctctgaaa aatccttttg ataaagcgaa tggacgaaag acacatagtc cttcgtcgta
     9541 atttctgtaa atagcagcgg ataatcggcg gcgaagtaac ggtgagtctt cagctgatct
     9601 gatgttttct gcggcatgcc ggcctccgct tcaattccgc acagtgtaaa gcgcccgctg
     9661 aaattgcggt tcacgcctgt cagcgtatta atcagtgtcg tttttccggc gccgtttacc
     9721 ccaagcaacc cgtaaacggc acctttttct aaatgtaaat ccacttgttc taagatgacg
     9781 ttgtcccgtt cataccaaac ggatacatcg tgtatatcca aaatgctcat cgcgagtcag
     9841 ccttccgcgc gcgcatcccg aacagaatgg caatggcaat gaaaatcagc gtaaacagat
     9901 aatcgctttt gacaaaatag acgactgcgc cgatgacaaa gataaatgaa aggatataca
     9961 gtaaaattct tctttgtgct ggtgacaaat cgtttccctc ctaaataagc tggaccacgt
    10021 cttctaattg ttcatttttc gcccaagagc aaatgttttt ccggtgatat ttgttagagt
    10081 tcagcccttt taagtaacag cctccgcaat agccgctgaa cgggcatttg tctttcatgc
    10141 aatgttcgct gaaccgcggc gcttgcgctt gccacagttt atggacgaga ggggagttaa
    10201 agatgctttc ataggaatca tgaaaaatat ttcccaatga aaattccttt ggaaagaggg
    10261 cgcaaggacg tacttcgccg aacgggctga tcacaatgga cttccagcca gcgccgcaat
    10321 ttgccgcgcg ttttcgttca taaggaataa tcggaatcag atctttaaac tcatcaatca
    10381 cattttgctc gtattccata aacttgcggt gctgctcggc gtctttcgtt ggatggacaa
    10441 tatccctgcc tcttccgaaa tcgtcaaccc aattgtaaga gaacgccttc gccccgagat
    10501 cccgaacctt ttgggccata tcgtggattt cccacatgtt tttttcgaag acagacatgg
    10561 cgactctgac aaatataccg tggtcactca acaattttat cgttttacaa gtttgggcaa
    10621 aagagccttt tctccctcta aaggagtcat ggacctcgga attgacacta tcaagagaaa
    10681 tgccgacaat gattttttgc ttgtaagcct tcaaaagctc caaactctct tttcgcatga
    10741 gtgttccgtt tgttaagaca gcgacttttt tgaacttttt acacacatag tcaagaatct
    10801 cattggcgtt tggatggaca aaaatttctc cgcctgtgat ttcgcatgtc aatacaccgt
    10861 tatcaaacag catatcagct gtttttttga attgctcaat cgacacggtg ccgagcgctt
    10921 caggtgagct ttccaaataa cagtgggcgc atttcaaatt acagcggtgc gtcagttcaa
    10981 aggtggcgtg caggggcatc ggaaattcat tgcttccgct cgtggtgatt gtatggcggc
    11041 tggcccggtt tccaagctga ataacctgct tgttctggag catgttgagc atgtcgtaat
    11101 accaatcttt atggtcttcc ggtgattcat catacactgc acattgctca gctaaaatct
    11161 gctcagctgt tttttggcca tccatgcgca tgcagagctc gtaagccgtt ttgttgagat
    11221 ccaaatactc aaagtcggaa atggagacat tatcgcgcaa gtagtcgatt tctaacacgc
    11281 cgccctcagg aagctggtga actcttacac tttcattaat aaatggaaac atctgctctc
    11341 taaacaaaat accatcccct atacatatga ttcaaatgaa aaacggttgt gtatgtatat
    11401 ccaagaggta gattttagtt aaaaattgta atttacttaa aaagggcata gtagaatgac
    11461 tatgcccttt tgggagatcc ttacccccat agaccgaata gacctgttgc accggcaatt
    11521 tcaaaatcag ggataggacc gtccactaga caagcggctc cgatcgagca tgttgcacaa
    11581 cctttgtttt ctacaatgac agcttttttc ataattgaat cctccctttt tttgtttttc
    11641 tagcagatct atgttgtact tttatcttaa aactatcaaa ttactaattc aatacatata
    11701 atttgaaaaa aatgtgaaaa ggaaatgata gatttcggaa aaatgtaaca tttcctaaag
    11761 gtaattagtg atatgatttt ctcttctata taaggaaatg ctttttatga ggtttatctt
    11821 caaatctgat gagcaatgat ggtaagatag aagcagttga agtttacaaa ccgaatgatt
    11881 atactattca agtcaaagtg gaatgatgaa aaggacgtgt cagaatgaag caagagacac
    11941 cgataacact ccatgtgaag tctgtgatcg aggatgacgg aaaccaagaa gtcatcgaat
    12001 tccgcaccac cggattttac tatgtaaaac aaaataaagt gtatctatct tattatgaag
    12061 aacacgactt aggcaaagtc aaaacgattg tgaaagtaag cgaaggcgaa gtcctggtca
    12121 tgaggtcagg cgctgtcaaa atgaatcagc gtttcgtaac gggagcttcc acaattgcta
    12181 aatataaaat gtcatttggt gagcttgagc tgaaaacaag cacaaaatcg attcaatctg
    12241 atctcgatga agaaaaaggc cgtatcagca tcgcatatga catgcatgtc ggagacgagc
    12301 aggagcattt acataatatg acgatcacgt atgagggagg aactcacgca tgaacattgc
    12361 ggaacaaatg aaggacgtgc tgaaagaaga aattaaagcg gccgttctga aagcgggact
    12421 ggctgaagaa agccagattc ccaatgttgt tttagaaaca ccgaaagata aaacacacgg
    12481 cgactactca acgaatatgg cgatgcagct ggcaagagtg gcaaaaaaag cgccgcgtca
    12541 aatcgctgaa gagattgtcg cccattttga taaaggaaag gcttcgattg aaaaactgga
    12601 tatcgccggc ccgggtttta tcaatttcta tatgaacaat cagtatttaa caaagctgat
    12661 tccgtctgta ctggaagcag gggaagcata cggggaaaca aacatcggaa acggtgaacg
    12721 agttcaggta gaattcgtat cagcgaatcc gacgggagac cttcacctcg ggcatgcgcg
    12781 cggggcggct gtcggcgatt ccttgtgcaa cgtgctttca aaagcgggtt acgatgtaag
    12841 ccgcgaatac tacattaacg atgcgggaaa ccaaatcaac aatctggcgc tttctgttga
    12901 agtccgttac tttgaagcac tcggattgga aaaaccgatg ccggaggatg gctaccgcgg
    12961 cgaggatatc attgcgatcg gaaagcgtct cgctgaggaa tacggtgacc gtttcgttaa
    13021 cgaagaggaa agtgaacgcc tcgcgttttt ccgtgaatac ggcctgaaat acgagctgga
    13081 aaagcttcgc aaggacttgg aaaacttccg tgtgccgttt gatgtgtggt attcagaaac
    13141 ttcactgtac caaaatggaa aaatcgacaa ggcgcttgaa gcgcttcgtg aaaaaggcca
    13201 cgtctatgaa gaagacggcg cgacttggtt ccgttccacg acgttcggcg atgataaaga
    13261 ccgcgtattg atcaagaagg acggcacgta cacgtacctg cttcctgata tcgcgtatca
    13321 taaggacaag cttgaccgcg gctttgataa gctgatcaac gtttggggtg ccgatcacca
    13381 cggctacatc ccgcgtatga aagcggcaat cgaagcgctg ggctatgaaa aaggaacgct
    13441 tgaagtagaa atcattcagc tcgttcacct ttacaaaaac ggcgagaaaa tgaaaatgag
    13501 caaacggacc ggtaaagccg taacgatgcg tgacctgatt gaagaagtcg gcttggatgc
    13561 tgttcgttac ttctttgcga tgcgaagtgc ggacacccat atggattttg acttagatct
    13621 tgctgtatca acatctaacg aaaaccctgt gtattatgca caatacgcgc atgcccgtat
    13681 ttgcagcatg cttcgccaag gggaagagca gggacttaaa ccggcggcag atcttgattt
    13741 cagccatatt caatcagaaa aagaatacga tctgctgaaa acgatcggcg gcttcccaga
    13801 ggcagtggcg gaagcagcag aaaaacgaat tccgcaccgt gtcacaaact atatttatga
    13861 tctggcttct gctctgcaca gcttctacaa cgcagagaaa gtcatcgacc ctgaaaatga
    13921 agagaaaagc cgcgcgcgcc tggctttaat gaaggcaacg caaattacgc tgaacaatgc
    13981 gcttcagctg atcggcgtat cggctccgga aaaaatgtaa tcacgatcaa aaggacaaag
    14041 tcttcgggct ttgtcctttt tttatgagaa aaacgtgtga tgtaattcac aatcctgttt
    14101 ggcgagtttt tgtatgataa gactgattat tgaatcattg aaaggggcaa gccaaatgat
    14161 caaccgtcaa cacattcaat tatcgttaca gtcattaagc ttggtggcag ggtttatggt
    14221 ttgggtgctg atttcatcac tcatttccca aatcacatta gatattcatt taagcaaggg
    14281 cgagatttct ttggtgacgg cgattcccgt tatcctcggg tcgcttctcc gcattccttt
    14341 agggtattta acgaacaggt ttggcgcgcg gctcatgttt atggtcagct tcatcctgct
    14401 tttatttcct gtattttgga tcagtatcgc ggactctctg tttgatttaa tcgcaggcgg
    14461 ctttttctta gggatcgggg gagcggtgtt ttccattgga gtgacctccc tcccgaaata
    14521 ttatccgaaa gaaaagcacg gtgtcgtcaa tgggatttac ggtgcaggaa atatcgggac
    14581 agccgttacg acatttgcag cgccggttat cgctcaagcc gtcgggtgga aatcaaccgt
    14641 gcagatgtat ctggttttgc tggctgtctt tgccttactg cacgttttgt tcggcgacag
    14701 gcatgagaag aaggtcaaag tttctgttaa gactcaaatc aaagccgttt accgaaatca
    14761 tgtgctatgg tttctgagcc tgttttattt tattacgttc ggtgcctttg tcgccttcac
    14821 tatctatctg ccgaactttc tggtcgagca ttttgggctg aatcctgcag atgccggctt
    14881 gcggacggct ggctttattg cggtttctac gctgctcagg cctgcgggtg gattcctggc
    14941 tgataaaatg agcccgctcc gcatcttaat gtttgttttt gccgggctta cattatcagg
    15001 cattatccta tcgttctcgc cgacaattgg cctttatacg tttggatcat taaccgtggc
    15061 cgtctgctca ggcataggaa acgggactgt ttttaaactg gtgcctttct atttttccaa
    15121 gcaagcgggg attgccaatg ggattgtgtc tgccatgggc ggattaggcg gcttttttcc
    15181 tccgctcata ttggcgagtg tgtttcaggc aacaggccag tacgcgatcg ggtttatggc
    15241 gctttcagag gtggcgttag ccagttttgt ccttgtcata tggatgtatt ggcaggaaag
    15301 aatgaaaaca cacacggaga gaaacagcca gagcatcaac taacactggg gcattcacaa
    15361 gattgttagt tttttctcga tgggtacaaa tcaattcacg ttacaataaa cacacaacgt
    15421 gactttcttc gaggtgagct catgaatttt ctctctgttc gaccatctga tagtgatctt
    15481 atttccagcg atctgcatga attgctggaa tcgatcagca cgaaaagaaa aatggaaaaa
    15541 cacacgtatt tgtttcgaga aggaatggat gcagaagagc tttatctgat tcaatcagga
    15601 ctcattgaaa tcggcaagct gacatctgat ggaaaagacc tgacgcttag aatctgccaa
    15661 aagcatgata tcgtcggaga attaacactt ttcactgaag aaccaaggta tatgctcagt
    15721 gcaaaagtgc tagaggatgg cgaggtgctc gtcattaata aaaataagct ggaaaaagaa
    15781 ttaatccaaa acggcgcttt gacatttgag ttcatgaaat ggatgagcac gcacctccgg
    15841 aagattcagt ccaaaatcag ggatctgctt cttcatggca aaaagggggc gctctattct
    15901 acccttatcc gcttatcaaa cagctacgga gtggagcgaa gcgacggcat tctgattaac
    15961 attgtcctga caaatcagga tttggcaaag ttttgcgcgg ctgcacggga aagcatcaac
    16021 cgtatgctgg gagatctccg caaaaaaggg gttatttcga tagacgaatc cggaaaaatt
    16081 attttgcaca agcgggacta tttacgatgt gagattgagt gtgaaaattg cccgctggag
    16141 atttgcaata ttgactgaaa aaaacaagga cagcggtgtc cttgtttttt ttaccttgtg
    16201 ataaacaggc acatgacggc aagaaagaag caggcattca agatttccag aatgccaatc
    16261 gtttttacgg gccaatccct tccatgaaaa aaccatgccc gcaagctgct cgggataaaa
    16321 gcgagaaacg cccatcctgc tccgaaaaga gcggataaaa aggggagcag caggtgatat
    16381 ccccatgacc agtatgcaaa tgtcctgttt tttctttcac gaatcaccga tttcacataa
    16441 aaggaactcc cgataaaaaa taaagcagac tgcaagaaaa taaaccaagc ccagccgtcg
    16501 agggttccca tccccagcca gcagctcgca aacccgcccg aacaaaagaa caagacacct
    16561 gcaacatcat tcaatagggc tcgttcgttt tttctgcggg caaaatacat atgtatgaga
    16621 aacagcggca gtaaagaaac gcccacccag atgagaggcg gcttatgaaa gaccgagatc
    16681 atcaaaaagc agcaggcggg aaaaccgtaa taacacatcc acttttgata tggtttgctt
    16741 tgtttctttt ttaaggcaag cgtaacggga taaaccgcta agtataggaa aagccagcct
    16801 aggaagagcg gaatatgcca aataacgggg cctcccttag ccatgccgag taaaaatggg
    16861 atcagcagca tcgcccacgc gccgtgctgc ttcggaatca gcgccttcat cgaaatcctc
    16921 cttttttctt tcattataaa tgcagtcacc ctcctgataa gtgacattca tcatacaggc
    16981 tgtgaaatac atcactgctg tacaggctca gtcgagctac actaaagcta tccttagcac
    17041 aggaggtttt cctatgaatc agtgtgacta tttattattt ctgaaacaac ttcctatgtt
    17101 taatgaagtg cctctatcca ttgtcgaaac cttgctgaaa aacggcacgt ttatccgcgg
    17161 ctcatgtgat cagtctccat cttttcttca ttctcaatct gtttatattg tattaaaagg
    17221 cagtgtccgt ttcgtggaca gcaggctccc tgaagggtcg aaaaccgttg cgctgtggga
    17281 aaaaggggat gtgtttccga ttgatgaaaa aggcgggctt tatttatcgc cctttatctc
    17341 agtcaatgcc acttcagaca ttctgattct caatatccca tattacatat ttaagaaaat
    17401 gatgtcttac catccgcagc tgcaaatgaa ctttttggct atgcttcagc aaaatgtttt
    17461 ttgttcctat caattatttt tgcggtatct gcatacatca caggatgaga acgctgagcc
    17521 cggttcttaa atagagccgg ttttttttga tctttgaatg aaaggcggct aatgacccaa
    17581 gcgtcctgcc tgaacgcagc cttcctcaca tcctgtgaaa atccttcctt ctcctttgtg
    17641 tgaacatttt gtgaaaaaag cagagtgtgt gacatagttc acaaggaaac acgctgtctc
    17701 tgtttatagt gaacttagca tcacctgact cggaaggagt gaactctcat gaagaaaaag
    17761 aaaaggagtc cgttgtttag gagattgaat tatttctctc ctatcgaaca ccattcaaat
    17821 aaacatagcc aaaccacccg cgaagatcgc gattgggaga atgtatacag aaacagatgg
    17881 cagtacgaca aagtcgttcg ctccacccac ggcgttaact gtacagggtc ttgcagttgg
    17941 aatatttatg tcaaaaacgg aattgtcacg tgggaagggc aaaatttgaa ttatccatca
    18001 acaggcccgg atatgcctga ttttgaaccg agaggctgcc cgcggggggc cagtttttca
    18061 tggtatatct acagcccgct gcgtgtgaaa tatccatacg tgcgcggtgt actgattaat
    18121 ttatggcggg aggcactgca agaacatcaa aatccattgg acgcctggaa atcgatcgtc
    18181 gaaaaccctg aaaaagcgaa gtcctataaa caggcgagag ggaaaggcgg ttttgtgcgc
    18241 gctgaatggc cggaggtgct gaagctgatt tcagcctctc tgctgtatac agtgatgaaa
    18301 tacgggcctg acagaaacgt cggtttttct ccgattccgg ccatgtccat gatcagccat
    18361 gcatcaggct cccggtttat gtcgttaatc ggaggcccta tgctcagttt ttatgactgg
    18421 tatgcggatc ttccaccagc atccccgcaa atttggggtg accagacgga cgttccggaa
    18481 agcagtgatt ggtacaattc cggctatatc atcacatggg gctccaacgt tccgttaacg
    18541 agaacgcctg acgcgcattt tttggcggag gcccgctata aaggcgctaa ggtcatttcg
    18601 atcagtccgg attttgcgga atcctcaaag ttcgcggatg actggctgag tattcgccaa
    18661 gggactgacg gggcacttgc gatggcgatg ggtcatgtca ttctgcagga attttacgtg
    18721 aaccaagaaa ctgaacgttt tattgagtac gcgaagcaat acactgattt tccatttctc
    18781 gtcaccctgt caaaagaaaa tggcgtatac acagcgggac ggtttctgca tgcgaaggac
    18841 atcgggcgga agacaaagca tgatcagtgg aagcctgcgg tttgggatga acagacaagt
    18901 tcatttgcca taccccaagg gacaatgggc tcgcgctggg acgggcagca gaaatggaac
    18961 ctgcacatga ttgatgaaga aaccggggaa ccgattgaac ctcgtctctc tgttctggga
    19021 atagaggacg agatcggcac ggtgcgcatc ccgtattttt caaatgacgg aaacaaagtg
    19081 ctcgagcggg atcttcctat taaaaaaatg aacctgaacg gtgaagaaac gtacatcacg
    19141 accgtgtttg acttgatact ggctaactac ggcgtgaacc ggggtatcgg cgaacgatcg
    19201 gctgtctcct atgatgatcc tgagccgttt acgcctgcct ggcaggaaca aatgacagga
    19261 atcaaaaaag aagctgtcgt taagattgcc agagagtttg cccaaaatgc gatcgataca
    19321 gacggccggt ccatgattat cgtaggggcc ggcattaacc actggttcaa ctccgacacg
    19381 atctaccgag cggtgttaaa tcttgtttta cttgtaggcg cccaaggcgt aaacggcgga
    19441 ggctgggccc attacgtggg gcaggaaaag ctccgacctg ctgaagggtg gcagacgatt
    19501 gcgactgcaa aggactggga aggcgtgccc aagctgcaaa acggcacctc atttttctac
    19561 tttgcgacag atcagtggcg ttatgaggac cagccgatca gtgatttggc atcaccgatt
    19621 gctgcgtcat cccgctacaa gcaccacgct gattacaatg tgctggccgc gcggctgggg
    19681 tggcttccgt cttacccgac tttcaatcaa aatggcatcg atctgtataa agaagctgaa
    19741 aaagcagggg cagaaacacc tgaagacgtt ggtgcgtacg tggcctcaca gctccaagag
    19801 aaaaaactga aattcgcgat tgaagatcct gataatgaag tgaattttcc aagaaatctt
    19861 ttcgtatggc gggcaaatct gatctcaagc tcaggaaaag ggcatgaata ttttctcaag
    19921 catttgctgg ggacgacgaa cggcttgatg aatgacgata gcgacagcat ccgccctgaa
    19981 gaaatcaaat ggcgggagca ggcgccggaa ggaaagctcg acctgttaat caatcttgat
    20041 tttcgaatgg cgggtacggc gctgtattcc gatatcgtgc tgccggcggc gacatggtat
    20101 gaaaaacacg atctcagcag cacagatatg catccgttca ttcatccatt tgctcctgcg
    20161 atctcggctc cgtgggaatc gaagtcagac tgggatattt tcaaggcgct gtcaaaagct
    20221 gtttccgatc tggcagaaga agtcgatatg gagccggtga aagaagtggt tgcgacgccg
    20281 ctcctccatg acaccatgca ggaattggcc cagccattcg gcaaaatcaa tgactggagc
    20341 aaaggcgaat gtgaagccat tccgggaaaa acgatgccga acatccaagt cgttgaacgg
    20401 gattacaaac acatttttca taaaatgacc gcactcggtc ctaacgctgc tttaaagccg
    20461 agcggaacaa aagggatgag ctggtcaata gccgatgaat atgaatcact caaaaagaga
    20521 ctgggagaaa tcacctcaga cagcgtggca aagggatgtc caaatataag tgaagcaaag
    20581 caggctgcag aagcgatttt aaccctatca tccacttcga atggaaaggt cgcagtaaaa
    20641 gcatgggaat cacttgaaaa catcacgaac ctgaagctga aagacctggc ggaagaacgc
    20701 gaggaagaat gctttacgtt cgaacaaatt acagcccagc cgaaaacggt gatcacgtct
    20761 ccagcgtttt ccggctctga aaaaggaggg cgcaggtatt cgccgtttac aacgaatgtt
    20821 gaaaaattaa ttccgtggcg gacgctgaca ggcagacaat cctattatgt cgatcatgaa
    20881 ctgatgatgg aattcggtga aacaatggcg acattcaaac cgatcctcca gcatcgcccg
    20941 tttctgagca agcggcctga tcaagaggga aaagaaatcg tccttaatta tttgacgccg
    21001 cataataaat ggtctgtcca cagcatgtat tttgattccc tgccgatgct gacgctgttc
    21061 cgcggcggac cgaccgtatg gatgaataaa gatgatgcag aggatacgga tatcaaagac
    21121 aacgattgga ttgaatgctt caaccgaaac ggcgttgtcg tcgcgagagc ggttttgtct
    21181 catcggattc ctaaaggaat ggcgtttatg caccatgccc aggaccgcca catcaacgtg
    21241 ccaggcacaa agctaacgaa taaccgcgga ggcacccata acagcccgac aaggattcac
    21301 gtcaagccga cacagatgat cggtggctac gcccagctca gctacggctt taattattac
    21361 ggtccaacgg ggaatcagcg cgacctgaac gtcgtcatcc gcaagctgaa ggaggtcgat
    21421 tggcttgaag attaaagcgc aaatcggtat ggtcatgaac ttggataaat gcatcggctg
    21481 ccacacgtgc agcgtcacct gcaaaaacac gtggacaaac cgttccggtg cggaatatat
    21541 gtacttcaat aatgtagaaa caaagccggg catcggctac ccgaagcaat gggaggacca
    21601 ggacaaatat aa
//
