LOCUS gnlProkkaNBMDOCCE_165 13052 bp DNA linear UNK 01-JAN-1980 DEFINITION gnl|Prokka|NBMDOCCE_165. ACCESSION gnlProkkaNBMDOCCE_165 VERSION gnlProkkaNBMDOCCE_165 KEYWORDS . SOURCE ORGANISM . COMMENT ##antiSMASH-Data-START## Version :: 7.1.0 Run date :: 2025-04-28 23:38:06 Original ID :: gnl|Prokka|NBMDOCCE_165 NOTE: This is a single region extracted from a larger record! Orig. start :: 0 Orig. end :: 13052 ##antiSMASH-Data-END## FEATURES Location/Qualifiers protocluster 1..13052 /aStool="rule-based-clusters" /category="RiPP" /contig_edge="True" /core_location="[2346:3052]" /cutoff="20000" /detection_rule="(TIGR04223 or AgrB)" /neighbourhood="10000" /product="cyclic-lactone-autoinducer" /protocluster_number="1" /tool="antismash" proto_core 2347..3052 /aStool="rule-based-clusters" /tool="antismash" /cutoff="20000" /detection_rule="(TIGR04223 or AgrB)" /neighbourhood="10000" /product="cyclic-lactone-autoinducer" /protocluster_number="1" cand_cluster 1..13052 /candidate_cluster_number="1" /contig_edge="True" /detection_rules="(TIGR04223 or AgrB)" /kind="single" /product="cyclic-lactone-autoinducer" /protoclusters="1" /tool="antismash" region 1..13052 /candidate_cluster_numbers="1" /contig_edge="True" /product="cyclic-lactone-autoinducer" /region_number="1" /rules="(TIGR04223 or AgrB)" /tool="antismash" CDS complement(339..1082) /locus_tag="ctg125_1" /transl_table=11 /translation="MISVYICEDDPKQLQQIRQIITKVIVDQQLDISICLACQDPHELL DKVNAQQPQKAIYVLDIALNSDINGIQLASQIRDMGRRSKIIFITTHTELSLMVFQYQV EALDFILKDFPDSLYERFSKVLHVAQDRFQTDENDQDDYVQIKIGETVRSINVKSIIFF ESSTSPHKIVVHLDDGELEYYGLLKDVPDLSPNFYRCHKSYVVNLKRIKSLDKHLRRLT MANGEKVLCSAQANRYLAKWLAKKS" CDS complement(1075..2337) /locus_tag="ctg125_2" /transl_table=11 /translation="MLMIVFQELSIYLIIKSLLRNIFFVRLFDVIFLSVCMLMSYIFLA KLGISFSFLMLMMFIFFTWWYVRVLSGALCITFQVFIWSIMVDHICDILTRLMKVPNGY VVVFVILSVVSLIFLNIVMDRTNFSPTFSNQSLNRITALLLMIIYLYIMLSEGLENQFQ VILSNLIILSVVMGLVLVIYNEYLRNVRAKYEVQKQRIQIQNDTRYMNEIEAHYNELRR FRHDYQNMLISIDEYLKTDDLEGLQEYYQKNLAPVSNRVLKEKYNLEDLSRVKVKSIKS ILFSKLSYAQSQEIEVHFDLKEPLIDITVNELDLDIALGIMLDNAIEASVGHADGEIMS AIFIEKNSTVFLIQNNVFEQLPPLWKLKEAGYSTKGKNRGIGLNSLSKIVNRNENMILE TRVLGAVFLQRLTVKRVSQND" CDS complement(2347..2475) /gene_functions="biosynthetic (rule-based-clusters) cyclic-lactone-autoinducer: TIGR04223" /gene_kind="biosynthetic" /locus_tag="ctg125_3" /sec_met_domain="TIGR04223 (E-value: 1e-08, bitscore: 25.3, seeds: 127, tool: rule-based-clusters)" /transl_table=11 /translation="MKEKMYKVLSHLFQYVGTKQLVMCCHGILFETKIPDELKSKD" CDS complement(2456..3052) /gene_functions="biosynthetic (rule-based-clusters) cyclic-lactone-autoinducer: AgrB" /gene_kind="biosynthetic" /locus_tag="ctg125_4" /sec_met_domain="AgrB (E-value: 1.7e-34, bitscore: 108.7, seeds: 181, tool: rule-based-clusters)" /transl_table=11 /translation="MEKPEQKLLLYKLSDRLFAAIQKNLQLERRQALLVKLGIDTVLNV IPKLIITIILALLLHELVPVLVFMGSFLVLRGFAYGRHLKSDLLCTILTIFVFVGVPYV IGTGISEVYRLLLSLIFVIIISIFAPADTVKNPITLKSLRKKLKRRAIGLSLILSLLQI VSNNYFGTIILIAMALAALLLMPYERRENYERKNV" CDS complement(3420..5534) /gene_functions="other (smcogs) SMCOG1223:ATPase (Score: 961.7; E-value: 5.4e-291)" /gene_kind="other" /locus_tag="ctg125_5" /transl_table=11 /translation="MANFYGNDPFFNNDMDDVFNQLFRRMDNQNSERARYLVNGQSLTP DEFAQYRATGKLPQNNKTIEVSKDGKQAVKKGGILEKLGTNLTEQARDGLLDPVIGREN EIQETAEILSRRTKNNPILVGDAGVGKTAVVEGLAQAIVAGKVPETIQDKEIYSIDLSS LEAGTQYRGSFEENIKQLVKEVKAAGNIILFFDEIHQIIGTGATGGEDGGKGLADIIKP ALSRGELTVIGATTQDEYRNTILKNAALARRFNDVVINEPTAADTLRILQGVKKLYEKH HHVVLPDDVLKAAVDYSIQYIPQRTLPDKAIDLIDMTAAHLAAKNSQTDVETLDQRVKK LEAAKEAAVKSEDFTKAADIKKSIEETKQKIKKTDQKEKITATIDDVAQSVERLTGIPV ADMGANDIEHLKNLDKRLKSKVIGQDEAVEMVAKAIRRNRAGFSEGDQPIGSFLFVGPT GVGKTELAKQLALDMFGNKNAIIRLDMSEYADRTAVSKLIGTSAGYVGYEDNANTLTER VRRNPYSIVLLDEIEKADPQVLTLLLQVMDDGRLTDGQGNVINFKNTIIIATSNAGFGN EALSGDKQRDQSLMDKLAPFFRPEFLNRFNGIVEFSHLTKQDLSQIVDLMLADVQKTLA KKSIKLEVTKAAKDWLMEQGYDEAMGARPLRRVIEQQIRDKVTDFYLDHLDVKNLKADL VDAEIVISAA" CDS complement(5925..6158) /locus_tag="ctg125_6" /transl_table=11 /translation="MSVENNYCKLQQAHDQKCRVSLRFYKTNGQMAETVGYVTTIVPKA IAFMAITGHRHLIQLNRIITVSLQSQDRRYVM" CDS complement(6787..7887) /locus_tag="ctg125_7" /transl_table=11 /translation="MTVINGYEQSDREQKLTILNLPSLEAAAKKIIPSGGFGYISGGSE DEWTLKQNTMAFNHVQIVPRALTDMEQPSTQTQAFGIDLKTPIMMAPAAAQGLAHARGE AATAEGMAQVGALMAQSTYSSTSIADTAAAGKGAPQFFQLYMSKDWDFNQSLLDEAVKA GAKAIILTVDATVDGYREADIINNFQFPIPMANLTKFSEGDGKGKGIMEIYAAAAQKIS PADVRRITEYTNLPVIVKGIQSPEDALLAIGAGAQGIYVSNHGGRQLNGGPASFDVLHE IAQAVNGRVPIIFDSGVRRGSHVFKALANGADLVALARPIIYGLALGGAQGVASIVSHL NDELLIDMQLAGTKTIEDVKRAKLLR" CDS complement(7914..9662) /gene_functions="biosynthetic-additional (rule-based-clusters) TPP_enzyme_N" /gene_functions="biosynthetic-additional (rule-based-clusters) TPP_enzyme_C" /gene_functions="biosynthetic-additional (smcogs) SMCOG1055:pyruvate oxidase/decarboxylase (Score: 472.1; E-value: 4.2e-143)" /gene_kind="biosynthetic-additional" /locus_tag="ctg125_8" /sec_met_domain="TPP_enzyme_N (E-value: 7.5e-42, bitscore: 132.8, seeds: 75, tool: rule-based-clusters)" /sec_met_domain="TPP_enzyme_C (E-value: 1.5e-32, bitscore: 102.5, seeds: 323, tool: rule-based-clusters)" /transl_table=11 /translation="MTKIKAGQALAQVLVDWNIDHIYGITADSINNTVDGFYQEKNHLK YIQVRHEEVGALAAAADAKLTGTIGVSFGSAGPGAVHLLNGLYDAKMDHVPVLALVGQS ATSIMNTNFFQEMNQDPIFADVAEFHKQVTTAEQIPYVVDEAIRSAYATRSVSVVIIPD DLCGQDIEFDGFKTASLSGSQQVLMPKLDDVQQTIAALKAAQHPVLWIGKGAYNARQEV IAVSEKFSLPVLSTAPATGIMPTDHPNFMGSRGRLGTKPAFEVSQAADLVLFVGTNFPF ARYLPQGIKFIQVNNNLADLGKQHDADITVLADAKEFFQALLQSEVTIKPTKFLKAAQR DKQNWNRWLKTIATDDQGGLTAEGVLEAIKDNATDDAVFGLDVGNNTEWAIRQLPLNKQ QTFTMSAWYGTMGFGLPAGLAAQLNYPKKQVWSISGDGGYAMVMPDLLTEVKYHLPVIN VVLENKVLGFIQHEKLLANQAPYGIDLIGADWAKMADNMGAIGFKVTNLKELKATFQKV TQLQQNGNQLPIVIDAKIKNVDPIDTSFVPVDPENFDADTIAKYRERYGIAEADQPALS QLLNEL" CDS complement(9750..10175) /locus_tag="ctg125_9" /transl_table=11 /translation="MANTQLSDATHIMAYIALHTDDQLKSEHIASSLNTDPTMVRRMMS KLRKAGLLTSVRGVARPTLACSPNDITLKDIYVAVVAKRSFLNVDHNTSETCPVGSVIP RVMEKYYCDIQNSAEARMSRVTLQDIIDDISAVQQQA" CDS complement(10348..12159) /gene_functions="biosynthetic-additional (rule-based-clusters) TPP_enzyme_N" /gene_functions="biosynthetic-additional (rule-based-clusters) TPP_enzyme_C" /gene_functions="biosynthetic-additional (smcogs) SMCOG1055:pyruvate oxidase/decarboxylase (Score: 494.2; E-value: 8.6e-150)" /gene_kind="biosynthetic-additional" /locus_tag="ctg125_10" /sec_met_domain="TPP_enzyme_N (E-value: 6.4e-45, bitscore: 142.8, seeds: 75, tool: rule-based-clusters)" /sec_met_domain="TPP_enzyme_C (E-value: 7.1e-39, bitscore: 123.1, seeds: 323, tool: rule-based-clusters)" /transl_table=11 /translation="MVMKQTKQTNILAGAAVIKVLEAWGVDHLYGIPGGSINSIMDALS AERDRIHYIQVRHEEVGAMAAAADAKLTGKIGVCFGSAGPGGTHLMNGLYDAREDHVPV LALIGQFGTTGMNMDTFQEMNENPIYADVADYNVTAVNAATLPHVIDEAIRRAYAHQGV AVVQIPVDLPWQQIPAEDWYASANSYQTPLLPEPDVQAVTRLTQTLLAAERPLIYYGIG ARKAGKELEQLSKTLKIPLMSTYPAKGIVADRYPAYLGSANRVAQKPANEALAQADVVL FVGNNYPFAEVSKAFKNTRYFLQIDIDPAKLGKRHKTDIAVLADAQKTLAAILAQVSER ESTPWWQANLANVKNWRAYLASLEDKQEGPLQAYQVLRAVNKIAEPDAIYSIDVGDINL NANRHLKLTPSNRHITSNLFATMGVGIPGAIAAKLNYPERQVFNLAGDGGASMTMQDLA TQVQYHLPVINVVFTNCQYGFIKDEQEDTNQNDFIGVEFNDIDFSKIADGVHMQAFRVN KIEQLPDVFEQAKAIAQHEPVLIDAVITGDRPLPAEKLRLDSAMSSAADIEAFKQRYEA QDLQPLSTYLKQFGLDDLQHQIGQGGF" CDS complement(12477..12887) /locus_tag="ctg125_11" /transl_table=11 /translation="MQGKRPDLDQRIQNAVFGLPLVRPDEQHRCLGTFYERIELRISFA EALKYNCSDVLQRLLKENSKYQLLINGQLDMDIMGQYIQSAKQNGVLFAIRNSQYYRAD SNSAAVILCADHDLNRDTVDVLERYPQLNKDV" ORIGIN 1 ctcgttaaaa ttcatcacag cgtattgatc gacattaact tctgcctgtc acaacatcct 61 ttaaactaaa cgcattcgtt actgtcatga ccaatccaat accccgtgaa cacatcttta 121 ttataggctc tgaacaaggg acataccgac cgttttaaga cgaataatct gaggataatc 181 gttttaagta cacttttaaa cggtttagga aagaacgaac ccagtacacg taatgctgac 241 aaataccact gcaatttcta atcgaataac gctgaatttt catcacgtag cacataaaaa 301 gtcgcctact aatttggcag gcgacttcct tggaactatt atgacttttt agcaagccat 361 ttagctagat aacgattagc ttgtgcagaa caaagcactt tttcaccatt tgccatggtt 421 aatcgtcgca agtgcttgtc caatgactta atgcgtttca agttaacaac atatgactta 481 tgacatctat agaaattagg actcaaatca ggaacgtcct ttaacagtcc atagtattct 541 aattcaccat catccaaatg gactacgatt ttatggggac tggttgaact ttcaaaaaat 601 ataatgcttt taacattaat tgatctgacc gtctcaccaa tttttatttg aacatagtcg 661 tcttggtcat tttcatcggt ttgaaaacga tcttgtgcca cgtgtaaaac cttgctaaat 721 cgctcataca aggaatctgg aaaatcctta agaataaaat ctaatgcctc aacttgatat 781 tgaaacacca tcaaagataa ctccgtgtgt gtcgtgataa aaataatctt gctgcgccgg 841 cccatgtcac gaatctggct agctagttga ataccattaa tatctgaatt aagggcaata 901 tctaacacat agattgcctt ttgaggctgc tgtgcattaa ccttgtctaa caattcgtgg 961 ggatcttggc atgctaaaca gatacttatg tctagctgtt gatcgacgat taccttagta 1021 atgatttgcc gtatttgttg taattgtttc ggatcatctt cgcaaatata gacactaatc 1081 attctgagat actcgcttca ccgtcaagcg ttgtaagaat accgctccta agactctggt 1141 ttcgagtatc atgttctcat tgcgattaac aatcttactt aaactattca atccaatccc 1201 ccgattcttg cccttagtgg aataacctgc ctctttcagc ttccataagg gtggtaactg 1261 ttcaaaaaca ttgttttgaa tcaagaacac cgtactattt ttttcgataa aaatggcact 1321 cataatctct ccatcagcat gtcctaccga tgcttcaatt gcattatcca acataattcc 1381 taatgcaatg tctaaatcca attcattaac agtaatgtca attaatggtt cctttaaatc 1441 aaaatgaact tcaatctctt gcgattgtgc atagctcaac ttactaaata ggatactctt 1501 aatcgacttc actttgaccc gactcaaatc ttcaagatta tatttttctt ttaacacccg 1561 atttgaaacc ggtgcaagat tcttttgata atattcttgt aaaccttcta aatcatcagt 1621 tttcaaatat tcatctatcg aaatcaacat attctgatag tcatgtctga aacgtcgcaa 1681 ctcattatag tgagcttcga tttcattcat atagcgagta tcattttgta tttgtattct 1741 ttgcttttgg acttcatatt tggctcttac atttcttaaa tattcgttat aaatcaccaa 1801 tactaacccc attacaactg acaatataat taaattactt aatataacct ggaactgatt 1861 ttccagacct tcactcaaca taatatacaa gtatattatc attaataata gtgcggttat 1921 gcgatttaag ctctgattac taaacgtggg actgaaattc gtgcgatcca ttacaatatt 1981 aagaaaaatt aagcttacga cactcaatat gacaaacact accacatacc cattaggaac 2041 tttcattaaa cgagttaata tatcacaaat atggtcaacc ataatcgacc atatgaacac 2101 ttgaaatgtt atacatagtg caccgcttag aactcgtaca taccaccaag tgaaaaatat 2161 aaacatcatt aacattaaaa aagaaaaact aattcctaac tttgctaaaa aaatataact 2221 catcagcata cagacggata aaaatataac atcaaaaagt ctcacaaaaa atatatttct 2281 caacaaagat ttaattatca aatagataga taattcttgg aagacaatca ttaacatata 2341 tctacactaa tccttgcttt ttaattcatc aggaatttta gtttcgaata atatcccatg 2401 gcagcacata accaactgtt tagtacctac gtattgaaaa agatggctaa gtactttata 2461 cattttttct ttcataattt tccctccttt catagggcat tagtaataaa gcggctaatg 2521 ccatcgcaat taaaatgatt gtgccaaaat aattattact aactatttgt aacaaactca 2581 aaattaatga caatccaatt gcccgtcgct ttaatttttt tctcaatgac ttcaatgtaa 2641 taggattctt taccgtatca gctggagcaa aaatacttat gattattaca aatattaaac 2701 ttaataacaa tctgtatact tcagaaatac cagttccaat cacatacggc acacccacaa 2761 acacaaagat agttaatatc gtacataaca aatccgattt caagtgacgt ccataggcaa 2821 agccacgcaa aactaaaaaa ctacccataa aaactaacac tgggaccaac tcgtgtagca 2881 gcaacgctaa gataatagta attatcagct taggaataac atttaataca gtatcaatgc 2941 ctagtttaac tagtaatgcc tgccgtcttt ctagttgaag attcttttga atcgcagcga 3001 ataaccggtc gcttaattta taaagcaata gtttttgttc tggcttttcc atatcccact 3061 cctataatgc tcaaatacat acctgtatca acagtttaaa acagtattaa ttaattgaaa 3121 agaatacata aatagattaa ttattcaata ttgttttaag actagaaata aacatttaaa 3181 gatacatcag tttaattatt catacgaaac taaagtttca tataaaaaga tcgttaatat 3241 aaatcagttt catcgatact cccccttaat ttttccttag attacaagtc aaactagact 3301 taatttcact aattcacatt actcaataga ttaatatcaa atggtgaaaa tcaacgaaaa 3361 aaggagatct atcaagcaat ctcctcttac ataaagttat ttatgaacac tgatttaagc 3421 taagctgccg atatcacaat ctcagcatcc actaaatcag ccttcaagtt tttgacatct 3481 aagtggtcaa ggtagaaatc cgttaccttg tcacgaattt gttgttcaat tactcgccgt 3541 aatggccgcg cacccattgc ttcatcatag ccttgttcca tcagccaatc tttggccgct 3601 ttagttacct caagtttgat ggattttttg gctaacgttt tttgtacatc cgccaacatc 3661 aaatcgacaa tttgacttaa gtcttgctta gtcagatgtg aaaattccac gattccatta 3721 aatcggttca gaaattctgg gcggaaaaat ggtgctaatt tatccattaa tgactgatct 3781 cgttgcttgt caccacttaa tgcttcatta ccaaagccag cattagaagt agcgataata 3841 atcgtatttt tgaaattaat gacattgcct tgtccatccg ttaagcgccc atcatccatc 3901 acttgtaaca gtaacgttaa tacttgtgga tcagcctttt caatttcatc taataataca 3961 atggaatatg gattacgccg aacccgttca gttagagtat tagcattatc ttcatagcct 4021 acgtatccag ccgaggtacc aattaatttc gacacagctg tacgatcagc atattcactc 4081 atatctagcc gaataatcgc atttttattt ccaaacatat ctaaggctaa ttgcttagct 4141 aattcagtct ttcctacgcc agttgggccc acaaacagaa aacttccaat tggctgatca 4201 ccctctgaaa agcccgcacg gttacgccga attgccttcg ctaccatttc aaccgcttca 4261 tcttgaccga ttaccttact tttcagacgc ttatcaagat ttttcaagtg ctcaatatca 4321 ttagcgccca tatcagcaac tggtatacca gttaaacgtt caaccgattg tgccacatca 4381 tcaatcgtgg cagtgatttt ttctttttga tccgtttttt taattttttg cttggtttcc 4441 tcgatcgact tcttgatatc agcggctttt gtaaagtcct ccgatttaac ggcggcctcc 4501 ttagctgcct ctaatttttt aacgcgttga tccaatgtct caacatcagt ttgcgaattt 4561 ttagccgcta aatgagccgc agtcatgtcg atcaaatcga tagctttatc tggcaaagtg 4621 cgttgtggta tatattggat tgaataatcc acagccgcct tcaaaacatc atctggtaat 4681 acaacatgat gatgcttttc gtacagcttt ttaacacctt gtaatatacg taaagtgtca 4741 gcggccgtcg gttcattaat cacaacatca ttgaatcgcc gtgccaaagc cgcatttttc 4801 aaaatagtat tgcgatattc atcttgagtc gtagccccga ttacagtcag ctcgccacgt 4861 gacaaagcag gtttaatgat atcagccaat cctttgccac catcttcacc accagtggcg 4921 cccgtgccga taatctgatg aatttcatcg aagaatagaa taatattacc agctgcttta 4981 acttccttta ctagctgttt aatattttct tcaaaagaac cgcgatattg agttcctgct 5041 tccaaagacg ataaatcaat cgaatagatt tctttatctt gaatcgtttc tggaacttta 5101 ccagccacaa ttgcttgtgc cagaccttcg acgactgcag ttttacctac accagcatca 5161 ccaactaaga ttggattatt tttcgtccta cgactcaaaa tttctgcagt ttcttgaatc 5221 tcattctcac gtccaatcac tggatctagt aatccatcac gagcctgttc cgtcaaatta 5281 gtccctaact tttctaaaat cccccctttt ttaacagcct gtttaccatc tttagatact 5341 tctattgttt tattattttg gggtagctta ccagttgctc ggtattgagc aaactcatcc 5401 ggtgtcagcg attgtccatt aactaaatac cgtgcacgct ccgaattttg attatccatg 5461 cgccgaaata attgattgaa aacatcatcc atatcattgt tgaaaaaagg atcatttccg 5521 tagaaatttg ccatattaca acacctccat aaaaatttat atgtgtaact tagtgaccat 5581 aatatccttt aaaactacaa ctgaatcgta tcacgatttt tatgtatcgt taagtaaagt 5641 gcttatagaa tcaattagaa ataattagaa taattttgtt taaacaaaag agaaatcaat 5701 ttcataaaat gaattgattt ccctacaagg ttccctattt aatagccctt gataaagaac 5761 ttgaattaac aagttacttt ccagaccaat tttaatttaa gagactgcga ctcaaaaagc 5821 acacccagta tcaagttaag gccaactagt tatcgttaat attgccactt aaatatcaat 5881 actagcaatc atgatacacg tgcaaaatca taaaccaaaa catattacat gacgtaacgg 5941 cggtcttggg actgtaaact cacagtaatg attctattga gttggataag gtgccgatga 6001 ccagtaattg ccataaatgc aattgctttc ggtacaatcg tagtgacata gccaactgtc 6061 tcggccatct gcccatttgt tttataaaac cgtaatgaga ctcgacattt ttgatcatgc 6121 gcttgttgta atttacaata attattttca acactcaaat taaagtctcc cgttcaaaga 6181 attcaggttt atttattcgt cagtgaatct atgtgtttgt ttttctcatt gttgacggcg 6241 taagtccaca ttaaggagtc agctattcag taaaaactaa ataactagta ttcatgttca 6301 gctcagtata atatgcattg atggttacta atcaaaaatc gatctctaaa tatcctaatt 6361 actatgaaac tttgaagtta atttatgaga aaaataactc acaacaaaac tcatgattac 6421 aaccttgtca tcataactag attatgaaac attcagcctc ctaaataaaa ctggtatgcg 6481 cgcatgtgta cagtatacta ttgccaagta tgtctgaata accgttttaa gacttgaaaa 6541 actcagctgg gtgctttagg acgctttttg tgcattttaa gacaatatcc taacttcaac 6601 gccggcatag cttcaattcg tcaatcagtg tcttagtttc tcagctattt ctgttcagaa 6661 catcttccta ttacaataaa aagcgttgat ctcagcagaa tttacttcca ccaaaaccaa 6721 cgctaaagtg ttattatatc aggtatttta aattcatttc agacattata ttcagcatta 6781 cttctactac ctaagtaatt tagcacgttt aacatcttca atcgtcttag ttcccgctag 6841 ttgcatatcg atcaacagct catcattaag gtgactcact atggaagcga caccctgcgc 6901 accacccaat gctaatccat agataatcgg ccgagcaagt gccaccagat ctgcaccatt 6961 ggctaacgcc ttaaagacat gggagccacg ccgaacaccg ctatcaaaaa ttattgggac 7021 gcgcccatta acggcttgcg caatctcgtg taaaacatca aaggaagctg gaccaccatt 7081 taattgccga ccgccatggt ttgaaacata gataccttga gcaccagccc cgattgctaa 7141 caaggcatct tctggtgact ggatcccctt cacaataact ggtaaattcg tatattccgt 7201 aatacgccga acatcagccg ggctaatctt ttgcgccgca gcagcataga tttccatgat 7261 acctttccct ttaccatccc cttcgctgaa cttagtcaag ttagccattg ggattggaaa 7321 ctggaaattg ttgataatat cagcttcacg ataaccgtca actgttgcat caactgtcaa 7381 aatgattgcc ttagcaccag ccttcactgc ttcatccagt aaactctgat taaaatccca 7441 atctttgctc atatataatt ggaaaaattg gggcgcacct ttaccagctg cggcagtatc 7501 tgcaattgac gttgaagagt aagtactctg agccataagt gccccaactt gagccatccc 7561 ttcagcagtc gcagcttcac cccgtgcatg tgccaatcct tgagcggccg ctggagccat 7621 cataataggc gttttgagat ctatgccaaa agcttgagtc tgtgtgcttg gctgttccat 7681 atccgtcaat gctcgtggca caatttgaac atggttaaag gccattgtat tctgctttaa 7741 agtccattcg tcttctgacc caccactaat ataaccaaag cctccgctcg ggatgatctt 7801 tttagcagct gcttccaatg atggtaaatt taaaatcgtt aacttttgct cacgatcact 7861 ctgttcatat ccattaataa ctgtcattat actaatctcc tttacataac cctttataat 7921 tcatttaata attggctaag tgccggttga tccgcttcag cgataccata tcgttcacga 7981 tacttagcaa tcgtatctgc atcaaagttt tctggatcta ctggaacaaa actagtatca 8041 attggatcaa catttttaat ttttgcatca atcacaattg gtagttgatt accattctgc 8101 tgtagttgag taactttctg aaacgttgct ttcaactctt taaggttagt cactttaaaa 8161 ccaatcgcac ccatgttgtc tgccatcttg gcccaatcag caccaatcaa gtcaatccca 8221 tacggcgcct gattagcgag taacttttca tgttgaataa agcctaatac tttgttttct 8281 aaaaccacgt taatgactgg caaatgatat ttaacttccg ttagtaagtc tggcatcacc 8341 atggcataac caccatcacc agaaatactc caaacctgct tcttaggata attcaattga 8401 gcggccaaac ctgctggcaa accaaaaccc atcgtgccat accaagccga catcgtaaaa 8461 gtctgttgct tattcaatgg taactgtcgg attgcccatt ccgtattatt cccaacatcc 8521 agaccaaaga cggcatcatc agtagcattg tctttaatag cttctagcac cccttcagcc 8581 gtcaaccctc cttgatcatc agtagcaatt gtcttgagcc accggttcca gttttgctta 8641 tcacgttgag cagctttcaa gaacttagtt ggcttaattg tcacttcgga ttgaagtaat 8701 gcttggaaaa attcttttgc atctgcaaga acagtaatat cagcatcatg ttgtttgcct 8761 aaatctgcta aattgttatt gacttgaata aacttaattc cttgtggcaa gtaacgtgca 8821 aacggaaagt tagtaccaac aaacaaaact agatctgccg cttgcgagac ttcaaaggcg 8881 ggtttagttc ctagtcgacc gcgagagccc atgaaattag gatggtcagt tggcataata 8941 ccagttgctg gagccgtcga caaaaccggc aaactaaatt tttcagaaac tgcgataact 9001 tcttgacgcg cattataggc acccttacca atccataaaa cagggtgttg agcagctttc 9061 aaagccgcta tcgtctgctg aacgtcatct aatttcggca ttaagacctg ttgactgccg 9121 ctaagtgaag ccgttttaaa accatcaaac tcaatatctt gaccacacaa atcatctgga 9181 ataataacaa cagaaaccga acgggtcgcg tatgctgatc taattgcttc atcaaccacg 9241 tatggaatct gttcagccgt tgtcacttgt ttatgaaatt cggctacatc tgcaaaaatt 9301 ggatcttggt tcatttcttg aaagaagttc gtattcataa tggatgttgc tgattgaccg 9361 actaaagcta gcaccggtac gtgatccatc ttggcatcgt ataatccgtt caagagatga 9421 acggcgcccg gtcctgctga accaaagcta acaccaatcg tccccgttaa tttagcatct 9481 gccgcggcag ctaaagcacc aacttcttca tgacgtactt gaatatactt caagtggttt 9541 ttctcttggt agaacccatc taccgtgtta ttaatcgagt cagctgtaat accatagata 9601 tgatcaatgt tccagtcgac caacacttgt gccaatgctt gtcctgcttt aattttagtc 9661 atttccatta ccctcttttt gttgttactt tttttagcac aactatatcc taaataaaaa 9721 cttgaccctt gtcaagtctt tatcttaaat tatgcttgtt gttgaacagc gctaatgtca 9781 tcaataatat cttgcagcgt cactcgcgac atacgtgcct cagcactatt ctgaatatca 9841 caatagtatt tttccatcac tcgcggaatt accgacccga ccggacacgt ctccgaagta 9901 ttatgatcaa cgtttaaaaa actacgctta gccaccactg ctacatagat atctttcaag 9961 gtaatatcat tgggcgaaca agctaatgtt ggtctagcaa cgccacgaac cgaagttaac 10021 aagcctgctt ttcttaactt actcatcatt cttctgacca tggtaggatc cgtatttaaa 10081 ctactagcaa tatgttcact tttcagctgg tcatcagtat gcaacgcaat atatgccata 10141 atatgcgtcg catcacttaa ttgtgtatta gccatctaga cacctcccat atccatctct 10201 attgttactt attttagcac atctaacgtg aacataaaag cgattaagga aataagttag 10261 gcttctttcc ctaatcgcaa cataagatta tttgataatc tccattaatt caatcaaact 10321 tattcaagac accgatagta gctgaattta aaacccaccc tgtccaattt gatgttgcaa 10381 atcatctaag ccaaattgtt ttaaataagt tgaaagtggt tgtaaatctt gagcttcata 10441 ccgttgttta aatgcttcaa tatcagctgc cgaactcatt gccgaatcta aacgaagctt 10501 ttcagcaggc agtggccgat ctcctgtaat caccgcatca atcagaactg gttcatgctg 10561 agcgattgct ttggcttgtt caaaaacatc aggtaattgc tcaatcttat taactcgaaa 10621 agcttgcatg tgcacgccat cggcaatctt actaaaatca atatcattga attcaacgcc 10681 aataaaatca ttctgattag tatcttcctg ctcatctttg ataaatccat attggcagtt 10741 ggtgaaaaca acattaatca ctggtaaatg gtattgaact tgcgtcgcca aatcttgcat 10801 tgtcatcgaa gcgccaccat caccagccag attaaacacc tgccgctcag gataattaag 10861 tttggcagca attgctcccg gaataccaac tcccatcgta gcaaataagt tagaagtaat 10921 gtgccgattg gatggcgtta atttcaaatg tcgattcgca ttcaaattga tatcaccaac 10981 atcaatcgaa tagattgcat caggctccgc aattttatta accgcacgta gcacttgata 11041 tgcttgtaaa ggcccttcct gcttatcttc taatgaagct agataagccc gccaattttt 11101 aacattggct aaattggctt gccaccaagg tgtcgactcc cgttcagata cctgtgctaa 11161 aattgcagcc agcgtctttt gtgcatcagc aagtaccgca atatctgttt tatgtcgttt 11221 acctaactta gccggatcaa tatcaatttg taagaaataa cgcgtatttt taaacgcttt 11281 ggaaacttct gcaaacggat aattattacc aacaaataaa acaacgtcgg cttgcgcaag 11341 tgcctcattc gccggttttt gtgccacccg attagcagaa cccaaatagg ctggataacg 11401 atccgcgaca atacccttag ctggatacgt actcattaat ggaattttca acgttttact 11461 caattgttcg agttctttac cagccttacg agctccaatg ccatagtaaa taagtggccg 11521 ttcagctgcg agtaaagtct gtgtcaatct cgtcactgct tgaacgtcgg gttctggtaa 11581 taacggcgtt tgataactat tagcggaagc ataccaatct tcagctggaa tctgttgcca 11641 tggtaaatcg actggaattt gcacaaccgc aacaccttgg tgcgcgtagg cgcgtcgaat 11701 tgcttcgtca ataacatgtg gcaacgtggc agcattgacg gctgttacat tataatctgc 11761 aacgtccgca taaatcggat tctcattcat ttcttggaac gtatccatgt tcatcccagt 11821 agttccaaat tgaccaataa gtgctagaac agggacatgg tcttcacgcg catcatataa 11881 cccattcata agatgagtgc caccaggtcc cgctgagccg aagcaaaccc cgattttacc 11941 cgttagctta gcgtcagcag cggcggccat tgcaccaact tcttcatgcc gtacttgaat 12001 ataatggatt cgatcccttt ctgctgataa tgcgtccata attgaattaa ttgaacctcc 12061 aggaatacca tacaaatgat ctactcccca agcttctaaa actttaataa ctgctgcacc 12121 tgctagtatg ttagtttgtt ttgtttgttt cataaccata ataaagcccc catttcatgc 12181 acaatttaat tacgcacaat ttaataaacg aatattacca tagcaaacgc ttacattcaa 12241 gtggtcataa actcatgctt tttaccactt aatcacgatt caaacgcatt gtagatcaac 12301 aacagcgcta gtctgcttgc cttgatgaac caccatcgct gttgaaaatt agtatctcat 12361 acattcattt tttaaacaat tttagtaatt agtgtatgtt ttacaggggc atacttccaa 12421 caatgtctgc aagtttagaa gctagccatt cttcgcctca cactactatt ttcgtttcat 12481 acgtccttat ttaattgtgg atagcgctct agcacatcta ctgtatcccg attcaaatca 12541 tgatcagcac ataaaataac tgcagcacta ttcgaatctg cacggtaata ctgactgttt 12601 ctaattgcaa ataacacacc attttgtttt gcagattgaa tatattgccc catgatatcc 12661 atatcaagct gaccatttat taacaattga tatttgctgt tttctttcaa aaggcgctgt 12721 aagacgtcac tacagttata ctttaacgct tcagcaaacg aaattcgcaa ctcaatacgt 12781 tcataaaaag tacctaaaca acgatgctgt tcatcgggtc tcactaaggg taacccaaac 12841 actgcattct gaattcgttg atctaaatct ggtcgtttac cttgcatact cacacctcat 12901 taagcaaaaa tttctgttct aaaagacaaa agaagatcca aacctcgcca agagattcag 12961 acccccattt aaaaatcaat tacgttgcat cgtatctaat ccgtaatgct ttaaattaag 13021 aaagatatgt ttatcgaaga aaccaatgaa cg //