LOCUS       c00016_gnlPro..        25340 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HBDJLCNB_16.
ACCESSION   c00016_gnlPro..
VERSION     c00016_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 00:26:58
            Original ID  :: gnl|Prokka|HBDJLCNB_16
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 171393
            Orig. end    :: 196733
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..25340
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[181393:186733]"
                     /cutoff="10000"
                     /detection_rule="(minimum(3, [Amidohydro_1, Amidohydro_3,
                     Arginase, FGase, Urocanase]) and Lyase_aromatic and
                     Urocanase_C)"
                     /neighbourhood="10000"
                     /product="histidine2glutamate_hutHGIU_operon"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..15340
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(3, [Amidohydro_1, Amidohydro_3,
                     Arginase, FGase, Urocanase]) and Lyase_aromatic and
                     Urocanase_C)"
                     /neighbourhood="10000"
                     /product="histidine2glutamate_hutHGIU_operon"
                     /protocluster_number="1"
     cand_cluster    1..25340
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(3, [Amidohydro_1, Amidohydro_3,
                     Arginase, FGase, Urocanase]) and Lyase_aromatic and
                     Urocanase_C)"
                     /kind="single"
                     /product="histidine2glutamate_hutHGIU_operon"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..25340
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="histidine2glutamate_hutHGIU_operon"
                     /region_number="1"
                     /rules="(minimum(3, [Amidohydro_1, Amidohydro_3, Arginase,
                     FGase, Urocanase]) and Lyase_aromatic and Urocanase_C)"
                     /tool="gutsmash"
     CDS             524..1861
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MmgE_PrpD"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_195"
                     /sec_met_domain="MmgE_PrpD (E-value: 9.5e-96, bitscore:
                     316.8, seeds: 231, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKQGLTAGLAEAVRTSQPEHSVDAIHEAKKGLLDFTAASFAGRE
                     DKGIQKLLRLIEDEGGRPLVPVIGQGKKAAPLQSAMLNGFIAHALDFDDVHSDVRGHPS
                     AVIVPALIASAARGHDERLLGAYVVGVEVMARLGESIGSRHYEKGWHNTGTLGAIAAAC
                     AVGYAEELTQEELEKAIGFAATQSAGMRVQFGTEMKPLHAGLAAQAGLLAVKLAQSEFG
                     GSRTALDGETGFFSLYGDVEKAQHTLLNDWGAPWRIVQPGLWFKIYPFCSAAHHAADAV
                     RQLISEETISAANTERIEVIFPPGGDAALTERSPKAGEEGRFSVEYVIALALHGHGLTV
                     EHFSSQPIPNGVQTTMGRIQRVYDNAIQPAPHAVPKGRFTIVRAYLSDGRICEARVDCP
                     KGAPGNELSEEDIIEKLTLTVPQEKARRIITAVEKADIKEFLAHIE"
     CDS             1931..3043
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) EutH"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_196"
                     /sec_met_domain="EutH (E-value: 8.5e-141, bitscore: 465.0,
                     seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVNDAVVFILAAFLLWGAADYCLGNRWGLGERFADGFKAMGPLA
                     LSMIGIVSLAPVLAAILIPIVAPFYTAIGADPSSFANTILAIDMGGYALAGEMAKDPQA
                     GLFSWVFLGTMMGPAIVFTIPVALGIIEKEDHPYFAKGILIGLCTVPIGCLIGGLCAGF
                     DIGMIGKNLLIPSLLSAVIAFGLWRYTDRMIQLFHLFGKAVSMVAIIGLAAVSVETMTG
                     IVLIPGMENVETGIQTTGTIAIALAGAFPMTAFITKTFKKPLQALGKCLHLDETATAGL
                     VTSLAHHIPMLASLKDMTPRGKVINVAFAVSGAFVLGSHLGFVAGMKKEMAAAMIIGKL
                     AGGVTAAAAAAWMTPAQSAKQQKRISASHS"
     CDS             3116..3943
                     /locus_tag="ctg16_197"
                     /transl_table=11
                     /translation="MAVKDRYMSKIKQETKPWIKRFGRLGYFAFGGVFILLGVLAFMTA
                     AGAGRAKDSSGALQTLSRMPYGSLLLFFIGIGLIGYVIWMVLSAIKDTEGHGNSRRGLS
                     RRIGNFFSAAVYTSIAWNALRFVFGQGDGGTSEQTWSAYVLAQPFGQWLTGLTGAGFIV
                     FAIVQFMKGVRAAFMKEFDTSKMNKQMICITKNTGRAGNIARAIIFSAIGYFLIKTAMT
                     ADPDDTRGFDGALAELAQQPHGKLILSILALGLILYGMYAIMKGIYQHMTWEK"
     CDS             4077..5018
                     /locus_tag="ctg16_198"
                     /transl_table=11
                     /translation="MDREKQQLSIEAARLYYQSDYSQQQIAEQLNISRPTVSRLLQYAK
                     EKGYVQIRVMDPFEDLDALGSILEEKYGLLEAHVVFSPTPDYAGITHDLSRYGAEYMHE
                     TVKDGDIVGVSWGTTMYQIAQNMQPKQVKGVEVVQLKGGISHSRVNTYSAETIQLFAEA
                     FQTMPRYLPLPVVFDNADVKRMVEKDRHIERIIEMGKQANIALFTVGTVRDEALLFRLG
                     YFNEEEKALLKKQAVGDICSRFFDAKGNICSSAINDRTIGVELQDLRLKERSILVAGGS
                     RKVSSIHGALTGKYANVLIIDQHTARALVNDL"
     CDS             5124..5795
                     /locus_tag="ctg16_199"
                     /transl_table=11
                     /translation="MSLANIIDHTALKPHTQKADILKLIEEAKTYKFASVCVNPTWVEL
                     AAKELKGTGVDVCTVIGFPLGANTTETKAFETKDAISKGATEVDMVINIAALKDKEDDV
                     VEADIRGVVEAVAGKALVKVIIETCLLTDEEKERACRLAVSAGADFVKTSTGFSTGGAT
                     KEDIALMRKTVGPDIGVKASGGVRTKEDVDTMVEAGASRIGASAGVSIVKGENASGGDN
                     Y"
     CDS             5876..7057
                     /locus_tag="ctg16_200"
                     /transl_table=11
                     /translation="MKYLIGIIGLIVFLGLAWIASSGKKRIKIRPIVVMLILQFILGYI
                     LLNTGIGNFLVGGFAKGFGYLLEYAAEGINFVFGGLVNADQTTFFMNVLLPIVFISALI
                     GILQKWKVLPFIIRYIGLALSKVNGMGRLESYNAVASAILGQSEVFISLKKELGLLNQQ
                     RLYTLCASAMSTVSMSIVGAYMTMLKPEYVVTALVLNLFGGFIIASIINPYEVAKEEDM
                     LRVEEEEKQSFFEVLGEYILDGFKVAVVVAAMLIGFVAIIALINGIFNAVFGISFQGIL
                     GYVFAPFAFLVGIPWNEAVNAGSIMATKMVSNEFVAMTSLTQNGFHFSGRTTAIVSVFL
                     VSFANFSSIGIIAGAVKGLNEKQGNVVARFGLKLLYGATLVSFLSAAIVGLIY"
     CDS             7087..8388
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_trans_3N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_3"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_201"
                     /sec_met_domain="Glycos_trans_3N (E-value: 2.4e-22,
                     bitscore: 74.5, seeds: 1422, tool: rule-based-clusters)"
                     /sec_met_domain="Glycos_transf_3 (E-value: 2.3e-53,
                     bitscore: 177.3, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRMVDIIIKKQNGKELTTEEIQFFVNGYTDGSIPDYQASALAMAI
                     FFQDMSDRERADLTMAMVNSGETIDLSAIEGIKVDKHSTGGVGDTTTLVLAPLVAALDV
                     PVAKMSGRGLGHTGGTIDKLEAIMGFHVELTKDEFIKLVNRDKVAVIGQSGNLTPADKK
                     LYALRDVTGTVNSIPLIASSIMSKKIAAGADAIVLDVKTGAGAFMKTEEDAAELAKAMV
                     RIGNNVGRQTMAVISDMSQPLGFAIGNALEVKEAIDTLKGEGPEDLHELVLTLGSQMVV
                     LAKKADTLDEARAKLEEVMKNGKALEKFKDFLKNQGGDSSIVDDPSKLPQAAYQIDVPA
                     KEAGVVSEIVADEIGVAAMLLGAGRATKEDEIDLAVGIMLRKKVGDKVEKGEPLVTLYA
                     NRENVDEVIAKVYDNIRIAAEAKAPKLIHTLITE"
     CDS             complement(8432..9046)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AA_permease"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_202"
                     /sec_met_domain="AA_permease (E-value: 5.5e-47, bitscore:
                     156.3, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VIESPFVAVFAEIGIPYAADIMNFVILTALLSVANSGLYASTRMM
                     WSLANENMISSRFKKVTSKGIPLNALMISMAVSCLSLVSSIVAPGTVYVVMVAIAGFAG
                     VVVWMSIALSQLLFRKRFLKKGGDVKDLTFRTPLYPLMPIAALLLCSASCIGLAFDPNQ
                     RIALFCGVPCIILCYLIYHFKRNVTKAKKISQEEYPADHIL"
     CDS             complement(9067..9795)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AA_permease"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_203"
                     /sec_met_domain="AA_permease (E-value: 6e-82, bitscore:
                     271.6, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISLGGVIGTGLFLSTGYTLHQAGPGGTILAYVIGGLMMYLVMQC
                     LGELSVAMPVTGSFQKYATTFIGPSTGFMVGIMYWINWVVTVGSEFTASGILMQRWFPD
                     SSVWMWSAIFAALLFICNAFSVKLFAETEFWFSSVKIVTIILFIILGGAAMFGLISLNG
                     TADAPMLSNFTDHGGLFPNGFLAVFIAMISVSFAFSGTELIGVTAGESANPQKDIPRSI
                     RNVAWRTVIFFIGAVFILSG"
     CDS             complement(10001..10345)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     histidine2glutamate_hutHGIU_operon: Arginase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_204"
                     /sec_met_domain="Arginase (E-value: 1.1e-21, bitscore:
                     73.5, seeds: 235, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LIQLGIREFSNSQAYEAYAKKHNVNIHTMDMIREKGLIPTIKEIL
                     PVVQDKTDFIFISVDMDVLDQSHAPGCPAIGPGGLYTDELLEAVKYIAQQPMLPGLKLL
                     KSTLPSIFEI"
     CDS             complement(10596..10889)
                     /locus_tag="ctg16_205"
                     /transl_table=11
                     /translation="LDKYPFLREAGSSFKDRDVTKMSDLIATWDGQDIKGPALIGVPLS
                     KSSISHSGASFAPGTIRQALKHSSAYSAELGEHVVSELLYDLGISIFMSLIS"
     CDS             complement(10882..12147)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     histidine2glutamate_hutHGIU_operon: Amidohydro_1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_206"
                     /sec_met_domain="Amidohydro_1 (E-value: 2.8e-19, bitscore:
                     65.5, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPKQIDTILINIGQLLTMESSGPRAGKSMQDLHVIEDAVVGIHEQ
                     KIVFAGQKGAEAGYEADEIIDCSGRLVTPGLVDPHTHLVFGGSREKEMNLKLQGISYLD
                     ILAQGGGILSTVKDTRAASEEELLQKAHFHLQRMLSYGTTTAEVKSGYGLEKETELKQL
                     RVAKKLHESQPVDLVSTFMGAHAIPPEYQNDPDDFLDQMLSLLPEIKEQELASFADIFT
                     ETGVFTVSQSRRYLQKAAEAGFGLKIHADEIDPLGGAELAGKLKAVSADHLVGTSDEGI
                     KKLAEAGTIAVLLPGTTFYLGKSTYARARAMIDEGVCVSLATDFNPGSSPTENIQLIMS
                     IAALHLKMTAEEIWHAVTVNAAYAIGKGEEAGQLKAGRSADLVIWQAPNYMYIPYHYGV
                     NHVHQVMKNGTIVVNREGAILG"
     CDS             complement(12160..13818)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     histidine2glutamate_hutHGIU_operon: Urocanase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     histidine2glutamate_hutHGIU_operon: Urocanase_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Urocanase_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_207"
                     /sec_met_domain="Urocanase (E-value: 2e-90, bitscore:
                     297.9, seeds: 148, tool: rule-based-clusters)"
                     /sec_met_domain="Urocanase_C (E-value: 7.2e-96, bitscore:
                     315.2, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="Urocanase_N (E-value: 1.8e-62, bitscore:
                     204.6, seeds: 71, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDVKKSIRANRGTELECLGWEQEAVLRMLRNNLDPEVAEKPEDL
                     IVYGGIGKAARDWDAFHAIEHSLKTLKNDETLLVQSGKPVGMFRTHPQAPRVLLANSVL
                     VPKWADWEHFHELEKKGLMMYGQMTAGSWIYIGSQGILQGTYETFAELARQHFGGSLKG
                     TLTLTAGLGGMGGAQPLSVTMNEGVVIAVEVDEKRIDKRIETKYCDRKTASIEEALAWA
                     EEAKLAGKPLSIALLGNAAEVHHTLLNRGVKIDIVTDQTSAHDPLIGYVPEGYSLDEAD
                     RLRQDTPELYVRLAKQSMKKHVEAMLAFQQKGSIVFDYGNNIRQVAKDEGLENAFDFPG
                     FVPAYIRPLFCEGKGPFRWAALSGDPADIYRTDALLKELFPTNKALHRWIDMAQEKVTF
                     QGLPSRICWLGYGERKKMGLAINELVRTGELKAPVVIGRDHLDCGSVASPNRETEAMKD
                     GSDAVGDWAVLNALVNTAAGASWVSFHHGGGVGMGYSLHAGMVAVADGSELADERLARV
                     LTSDPGMGIIRHADAGYERAVEVAKEQDIIVPMQK"
     CDS             complement(13886..15340)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     histidine2glutamate_hutHGIU_operon: Lyase_aromatic"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_208"
                     /sec_met_domain="Lyase_aromatic (E-value: 6.1e-197,
                     bitscore: 650.7, seeds: 479, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVTLDGSSLTTADVARVLFDFEEAAASEESMERVKKSRAAVERIV
                     RDEKTIYGINTGFGKFSDVLIQKEDSAALQLNLILSHACGVGDPFPECVSRAMLLLRAN
                     ALLKGFSGVRAELIEQLLAFLNKRVHPVIPQQGSLGASGDLAPLSHLALALIGQGEVFF
                     EGERMPAMTGLKKAGIQPVTLTSKEGLALINGTQAMTAMGVVAYIEAEKLAYQTERIAS
                     LTIEGLQGIIDAFDEDIHLARGYQEQIDVAERIRFYLSDSGLTTSQGELRVQDAYSLRC
                     IPQVHGATWQTLGYVKEKLEIEMNAATDNPLIFNDGDKVISGGNFHGQPIAFAMDFLKI
                     AISELANIAERRIERLVNPQLNDLPPFLSPHPGLQSGAMIMQYAAASLVSENKTLAHPA
                     SVDSIPSSANQEDHVSMGTIAARHAYQVIANTRRVIAIEAICALQAVEYRGIEHAASYT
                     KQLFQEMRKVVPSIQQDRVFSYDIDA"
     CDS             complement(15453..15908)
                     /locus_tag="ctg16_209"
                     /transl_table=11
                     /translation="VIHMTLHKERRIGRLSVLLLLNEAEESTQVEELERDGWKVCLGKV
                     GSMDAHKVVAAIETASKKSGVIQSEGYRESHALYHATMEALHGVTRGEMLLGSLLRTVG
                     LRFAVLRGNPYESEAEGDWIAVSLYGTIGAPIKGLEHETFGVGINHI"
     CDS             16515..17924
                     /locus_tag="ctg16_210"
                     /transl_table=11
                     /translation="MFNRLFRVCFLAALIMAFTLPNSVYAQKPIFKEVSVHDPSIIETN
                     GTFYVFGSHLASAKSNDLMQWQQLTTSVSNDNPLIPNVYEELKETFEWAQSDTLWAADV
                     TQLADGKYYMYYNACRGDSPRSAMGVAVADNIEGPYKNKGIFLKSGMEGTSSDGTPYDA
                     TKHPNVVDPHTFFDKDGKLWMVYGSYSGGIFILEMNPKTGFPLPGQGYGKKLLGGNHSR
                     IEGPYVLYNPDTQYYYLYLSYGGLDATGGYNIRVARSKKPDGPYYDAEGNPMLDVRGKG
                     GTFFDDRSIEPYGVKLMGSYTFETENEKGTGYVSPGHNSAYYDEKTGRSYLIFHTRFPG
                     RGEEHEVRVHQLFMNKDGWPVAAPYRYAGETLKEVKQKDITGTYKLIQHGKDISADIKQ
                     TINIQLNKNHTISGEMTGTWRKTGKNTADITLAGKKYNGVFLRQWDSVREKNVMTFSVL
                     NTSGEAVWGSK"
     CDS             18231..18596
                     /locus_tag="ctg16_211"
                     /transl_table=11
                     /translation="MHSEMLLHSVKADLHEKQEQIHQLKRVLHEIRQIKHDFSEAQHLI
                     HRPHLNREAWRGTHAERFEDIREGMNKAYQQIKSDQVSGIIESIEGKIHSLEGDVYSIR
                     RQITRIEHEIEKEKHKK"
     CDS             18608..18877
                     /locus_tag="ctg16_212"
                     /transl_table=11
                     /translation="MAQEIKMVYDTVKQGLSQLKNSAELKSSLPGHLSGRNHLNVVKSI
                     EQLNKDIKELTEAYASVLAKHIAQTESAVNAMKETDENISSSMK"
     CDS             18897..20606
                     /locus_tag="ctg16_213"
                     /transl_table=11
                     /translation="LKTLDVHALHEGIQHTIEKLDKQKQQLEKLEKSVEHLAGMKDALK
                     GKGGDAIRTFYEECHKPFLLFFGIFIDEYKKVLKQTQHAISSVESNSHGMIAEAFLSHD
                     ARHGVKHAREVTEQLTDAVNRQTSAIDHIVSLPTVNDSFFRMETEQAERLISDTLNKLF
                     QFDGQQTQALEAAKSDFQTMKKYIDQLETMYTGPKIEITGYKSGSILKSQEEENINQIF
                     GAINPQMKQADDSPMEMMLKKLAENEKSKVDSVVKTGDSKKVSKNIIVINGKVYNTSEH
                     REHIKTDFSNAEVKQVVYNDTLYNVYISGNDMKLEPVVSLSDIKVDENGYVKILETAVE
                     LTGVYDLFKAATGRDPVSGEKVTGKDRVVASINSVPFAKIAKLEKLIDINKLINNGKKA
                     KKASEVKNVAKDKGKIANDVSGSANKINSDLIKKYARDIEQRTGRELPKNQIDKLKEAL
                     RNKEYKKMSPIETAKHRTKFDKVKNKVIKEWEENTGQKWPVYKENVVSEKTGKIIRKKG
                     DKYDAHHIIENTFGGEHEWWNMHPAKFPNEHQAGIHGTGSPANELFKGGKKK"
     CDS             20603..21046
                     /locus_tag="ctg16_214"
                     /transl_table=11
                     /translation="MSYNFIKSNKENDFYPVNQSEIEEVEKNLNLKLPSELVNFYLEVG
                     YGFIKGSEFNTNRILDPYSVRDFRLRINDFEFYPDIEIYDEFENDKLIFFEGSESALMS
                     IELNDNNKNPIYYYDIQIATSLTEFLRKIEENDQYYLDLLDDE"
     CDS             21092..21400
                     /locus_tag="ctg16_215"
                     /transl_table=11
                     /translation="MLLINKQKDPVFQFLAGTFHQDIETPDDAIQELLIEESKEYLEDA
                     IVFLTDFIESEHSDNKKNDYIQSCADGVYLPAFNLEPIDWLKNVIVQIKKSLKKFKR"
     CDS             21783..23612
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTS_EIIC"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_216"
                     /sec_met_domain="PTS_EIIC (E-value: 1.2e-38, bitscore:
                     128.8, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYDKLSKDILQLVGGEENVQRVIHCMTRLRFNLHDNAKADRSQL
                     EQLPGVMGTNISGEQFQIIIGNDVPKVYQAIVRHSNLSDEKSAGSSSQKKNVLSAVFDV
                     ISGVFTPILPAIAGAGMIKGLVALAVTFGWMAEKSQVHVILTAVGDGAFYFLPLLLAMS
                     AARKFGSNPYVAAAIAAAILHPDLTALLGAGKPISFIGLPVTAATYSSTVIPILLSIWI
                     ASYVEKWIDRFTHASLKLIVVPTFTLLIVVPLTLITVGPLGAILGEYLSSGVNYLFDHA
                     GLVAMILLAGTFSLIIMTGMHYAFVPIMINNIAQNGHDYLLPAMFLANMGQAGASFAVF
                     LRSRNKKFKSLALTTSITALMGITEPAMYGVNMRLKKPFAAALIGGAAGGAFYGMTGVA
                     SYIVGGNAGLPSIPVFIGPTFIYAMIGLVIAFAAGTAAAYLLGFEDVPSDGSQQPAVHE
                     GSREIIHSPIKGEVKALSEVKDGVFSAGVMGKGFAIEPEEGEVVSPVRGSVTTIFKTKH
                     AIGITSDQGAEILIHIGLDTVKLEGQWFTAHIKEGDKVAPGDPLVSFDLEQIKAAGYDV
                     ITPVIVTNTDQYSFSPVKEIGKVQPKEALLALS"
     CDS             23645..25045
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_217"
                     /sec_met_domain="Glyco_hydro_1 (E-value: 1.2e-146,
                     bitscore: 484.6, seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNDFQKDFYGGGAVAANQVEGAYNEGGKGLSTADVSPNGIMSPF
                     DESMTSLNLYHNGIDFYHRYKEDIALFAEMGFKAFRTSIAWTRIFPNGDEEEPNEEGLR
                     FYDDLFDELLKHHIEPVVTISHYEMPLGLVKNYGGWKNRKVIEFYERYAKTVFKRYQHK
                     VKYWMTFNEINVVLHAPFTGGGLVFEEGENKLNAMYQAAHHQFVASALAVKAGHDIIPD
                     SKIGCMIAATTTYPMTSKPEDVFAAMENERKTLFFSDVQARGAYPGYMKRYLAENNIEI
                     EMAEGDEELLKEHTVDYIGFSYYMSMAASTDPEELAKSGGNLLGGVKNPYLKSSEWGWQ
                     IDPKGLRITLNTLYDRYQKPLFIVENGLGAVDKVEEDGTIQDDYRINYLRDHLIEAREA
                     IADGVELIGYTSWGPIDLVSASTAEMKKRYGFIYVDRDNEGNGTFNRIKKKSFNWYQQV
                     IATNGESL"
ORIGIN
        1 ccggacaaat catcagcggg ctgcaatctg tggtcagccg caatatcagc tcactgcaaa
       61 acgcagtcgt cagtatcaca agagtacagg cgggcacctc gtggaacgta attccagacc
      121 aagctgaaat ggaggggacg gttcgaacct ttcaaaaaga agcgaggcag gctgttcccg
      181 agcatatgag acgagtggct gaaggaattg cagcgggcta tggggcacaa gcagaattca
      241 agtggtttcc ttatttgcct tccgttcaga atgacggcac atttttgaat gcggcatccg
      301 aagctgcggc acggcttggc tatcaaaccg ttcacgctga gcagtctccg ggcggagaag
      361 acttcgctct gtatcaagag aagattccgg gattttttgt ctggatggga acgaacggga
      421 cggaggagtg gcatcatccg gcctttacac tggatgaaga agcccttacg gttgcctctc
      481 aatactttgc ggagctggcg gttattgtat tggagaccat caaatgagca aacaagggct
      541 gacagcaggt cttgcagagg ctgtgagaac gtcacaacct gagcattcag ttgacgcgat
      601 tcacgaagca aaaaagggat tacttgattt tactgccgct tcattcgcag gaagagaaga
      661 taaaggaatt caaaagctcc tccgtctgat agaggatgaa ggaggccggc cccttgttcc
      721 tgttatcgga cagggcaaaa aggccgcgcc attacaatcc gcgatgctca atggatttat
      781 cgcccatgca ttggattttg atgatgtcca ctccgatgta agaggacacc ccagtgcagt
      841 catcgtaccg gcccttattg cttctgccgc tcgcggacat gacgagcggc ttcttggcgc
      901 ttatgttgtt ggtgttgaag tgatggcacg gctgggagaa tcaattggca gccgccacta
      961 tgagaagggc tggcataata caggtacgct tggtgccatc gctgctgcct gcgccgtagg
     1021 ttatgctgag gagctgactc aggaagagtt ggaaaaagca attggttttg cggctacgca
     1081 atctgctggg atgagggtgc aatttggaac agaaatgaaa ccgctgcacg ccggtttggc
     1141 ggctcaggct ggcttgctgg ccgttaagct ggcccaatca gaatttggcg ggtcccgcac
     1201 ggcacttgat ggagaaactg gtttcttcag tctgtacggt gacgttgaga aagcacaaca
     1261 cactttgcta aacgattggg gggcaccgtg gagaattgtg cagccgggtc tatggtttaa
     1321 aatctatcca ttttgttccg cggcacacca tgctgcagat gcggtacgac agcttatctc
     1381 cgaagaaacc atttctgctg ccaataccga acgtattgaa gtgatatttc cgccaggcgg
     1441 agatgctgca ttgacggaaa gatctccaaa agctggagag gaaggccgtt tcagcgttga
     1501 atatgtgatt gctcttgctt tgcatggaca cggcctgacc gttgaacatt tcagcagcca
     1561 gccgatccca aacggggttc aaacgacaat ggggcgaatt cagcgcgtat atgacaatgc
     1621 tattcagccg gctcctcatg ccgttccaaa aggccgtttc acgattgtcc gggcctattt
     1681 atcagacggc cggatttgcg aagcgcgtgt ggactgccca aaaggggcac caggaaatga
     1741 gctgtctgaa gaagacataa tagaaaaatt gacattaacg gtcccgcaag aaaaagcgcg
     1801 acgcattata acagccgttg aaaaagccga tataaaagaa tttttagctc atattgaata
     1861 agatcaactc tattcggtga tttcagatga tatgataaaa ccaatcatac gtttgaaaaa
     1921 ggagaaaacc atgacggtga atgacgcggt tgtattcatt ttggctgcct ttttactatg
     1981 gggagcagcg gattattgtt tgggaaacag atgggggcta ggcgagcggt ttgcggacgg
     2041 ctttaaggct atggggccgc tggcgctgtc catgatcgga attgtatcgc tggcgcccgt
     2101 gctggcagca atcttgattc ccattgttgc tccgttttac acagcgattg gcgcggatcc
     2161 ttcttccttt gcgaacacca ttttggcgat tgatatggga ggatatgcgc tggctggaga
     2221 aatggcgaaa gatccgcagg ccgggctgtt ttcatgggtg tttttaggaa caatgatggg
     2281 gccggcaatc gtcttcacga ttcccgtcgc tcttggcatc atcgaaaaag aggatcatcc
     2341 gtattttgcg aaaggcatat taatcgggct gtgcacagtg ccgatcggtt gcttaatcgg
     2401 cggattatgc gcaggctttg acatcggcat gataggtaaa aatcttctga tcccgagtct
     2461 gttatctgct gtcatcgctt ttgggttatg gcgatacacc gacagaatga ttcagttgtt
     2521 tcatctcttc gggaaagcgg tcagtatggt tgcgattatc gggcttgcag ctgtttctgt
     2581 tgaaacgatg accggcattg tgctgattcc gggaatggag aatgtcgaga cagggataca
     2641 aacgacaggg accatcgcca ttgctctggc aggggcgttc ccgatgacgg catttattac
     2701 aaaaaccttt aaaaaaccgc ttcaggctct ggggaaatgc cttcatttag atgagacagc
     2761 aacagcaggc ttagtgacct ctttggcgca tcatatccca atgctggctt cattaaagga
     2821 tatgacgccg agaggaaagg tcatcaatgt cgcgtttgcg gtcagcggcg cctttgtact
     2881 cggcagccat ctcggttttg tagctggaat gaaaaaagaa atggcggcgg ccatgatcat
     2941 tgggaaatta gcaggcggag tcacagctgc cgcagcggct gcttggatga cacctgcaca
     3001 atcagctaaa cagcaaaaac gtatctcagc cagccatagc tgaggcagga gctgtttcaa
     3061 ctttgttcaa tcgggaatgt tacagtaaag atttctgtga aagagggttg gacacatggc
     3121 ggtgaaagac cggtacatgt caaaaataaa acaggaaacc aagccttgga tcaaacgatt
     3181 cgggaggctt ggttattttg cattcggcgg cgtttttatt ctgcttgggg ttttggcttt
     3241 tatgacggct gccggggcag gccgcgccaa agattcgagc ggagctctcc aaacgctatc
     3301 acgcatgccg tatgggtcac tattgctttt ttttataggc atcggcctta tcggctatgt
     3361 gatctggatg gtgttaagcg cgatcaagga cacggagggg cacggaaaca gcaggcgagg
     3421 cctgtcgcgg agaataggaa actttttcag tgccgctgtt tacacatcca tcgcttggaa
     3481 tgccttgcga tttgtgtttg gccaagggga cggcggcact tcagaacaga cgtggtccgc
     3541 ttatgtattg gcgcagccgt tcggccaatg gctcacaggg cttacgggtg cgggttttat
     3601 cgtatttgcg attgttcaat ttatgaaagg cgttcgggct gcttttatga aagaattcga
     3661 tacatcaaaa atgaacaaac agatgatatg catcacgaaa aacacaggac gcgcaggcaa
     3721 tatcgcccgg gccattattt tctcggctat cggctatttt ctcatcaaga cagccatgac
     3781 cgctgatccc gacgacacaa gaggctttga cggcgcgctc gcagaactcg cgcagcagcc
     3841 gcatggcaaa ttgattctgt ctatattggc attaggcctg atcctatatg gaatgtacgc
     3901 cattatgaaa ggcatttatc agcatatgac ttgggagaag taagctctgg gcaggtccgc
     3961 gcccagagcg tttttcagtt tcttagaaat caggtggatg aaagccggcg ccagcctgta
     4021 taataaaagc aaatcaaaag cagttttatc aggactgatc cacagggagg tgcagaatgg
     4081 atcgggaaaa acagcaatta agcatagaag cggcaaggct ttactatcag tctgactaca
     4141 gtcagcagca aattgctgag cagctcaaca tttcaaggcc aaccgtttcc cggctgctgc
     4201 aatatgcaaa ggaaaaaggg tatgtccaga ttcgcgtcat ggaccctttt gaggatttgg
     4261 atgcgctcgg ttccatactt gaagagaaat acgggctcct tgaggcgcat gttgtgtttt
     4321 ccccgacacc cgattatgca ggaattacac atgacctaag ccgctatggt gcagaatata
     4381 tgcatgaaac ggtaaaagac ggcgacattg tcggcgtcag ctggggaacc accatgtatc
     4441 aaatcgcgca aaacatgcag ccgaagcagg taaaaggcgt cgaggtcgtc cagctgaaag
     4501 gcggcatcag ccattcccgg gtaaacacgt attcggctga aacgattcag ctgtttgcag
     4561 aggcttttca aacgatgccg cgctatctcc cgcttcccgt cgtgtttgat aatgcggatg
     4621 tgaagcgaat ggtggagaaa gaccgtcata ttgaacggat cattgagatg ggcaagcagg
     4681 cgaatatcgc tctctttacg gtcgggactg tccgtgatga agcgctgttg tttcggctcg
     4741 gatattttaa cgaagaagag aaagccctgc tgaaaaaaca ggccgtcggg gatatttgtt
     4801 cacgcttttt tgatgcgaaa gggaatattt gcagcagcgc catcaatgac cggaccatcg
     4861 gtgttgagct tcaagacctt agactgaagg aacgctccat tttagttgcc ggcggaagca
     4921 gaaaagtatc ttccattcac ggagcattaa ccggaaaata tgccaacgtt ttaatcattg
     4981 accagcatac cgcgagggcg cttgttaatg atttgtgaca cgttcaaacc tttcattgaa
     5041 caaaatttca attaccaatt tacatatgtt caaaagtcgg ttatgctaaa aaatatctta
     5101 acaaaaaagg aagtgtgcga aggatgtcat tagccaacat aattgatcat acagctttga
     5161 aaccgcatac acaaaaagcg gacattctaa aactaattga agaagcgaaa acatacaaat
     5221 ttgcttcagt atgtgtcaat ccgacatggg tggagcttgc tgcaaaagag cttaagggaa
     5281 ctggagtcga cgtttgtacg gtcatcggct tcccgctcgg tgccaataca actgaaacaa
     5341 aagcgttcga aacaaaagac gccatttcaa aaggcgccac tgaagtggat atggtcatta
     5401 atattgccgc tttaaaagac aaggaagacg atgtggtgga agctgatatc cgcggtgtag
     5461 tggaagctgt agccggaaaa gcgcttgtca aagtcattat cgaaacgtgc cttctgactg
     5521 atgaagaaaa agaacgtgca tgccgtttag cggtgtctgc gggagcggat ttcgtaaaaa
     5581 catcaacagg cttttctaca ggcggcgcaa cgaaggaaga tatcgcctta atgcgcaaaa
     5641 cagtagggcc tgatatcggc gtgaaagcat ctggcggcgt cagaacgaaa gaagatgtag
     5701 acacaatggt agaggccgga gcaagccgaa ttggcgccag cgcaggcgtt tctatcgtaa
     5761 aaggagaaaa tgcatcaggc ggagacaact attaagagct gacggaaggc agactgcttt
     5821 ccgttttctg aggaaacagt aattgtaagc gaatacaaat aaaggagaaa cacatatgaa
     5881 gtatttgatt gggattatcg gtttaatcgt gtttttaggc ctcgcgtgga tcgcgagcag
     5941 cggcaaaaaa agaattaaga tccgcccaat tgttgttatg ctcattttgc aatttattct
     6001 tggctacatt ctcctcaata ccggaatagg gaatttcctc gtgggaggat ttgcaaaagg
     6061 attcggttac ctgcttgaat acgcggcaga gggaattaac tttgtgtttg gcggcttggt
     6121 gaatgcggac caaacgacat tctttatgaa tgttctcttg ccaatcgtgt ttatttccgc
     6181 tctgatcggg attctgcaaa agtggaaagt cctcccgttt atcattagat atatcggcct
     6241 tgccctcagc aaggtaaacg gtatgggaag attggaatcg tataacgcag tggcttctgc
     6301 gattttaggg cagtcagaag tatttatctc cttgaagaaa gaactcggtc ttttaaatca
     6361 gcagcgcttg tacacgcttt gcgcatctgc gatgtcaact gtatcaatgt cgattgtcgg
     6421 tgcgtatatg acaatgctga aaccggaata tgttgtaaca gcgcttgttt tgaacttatt
     6481 tggcggtttc attatcgctt ctattatcaa tccgtacgag gttgcaaaag aagaggatat
     6541 gcttcgtgtt gaggaagaag aaaaacaatc cttcttcgaa gtgctcggag aatacattct
     6601 tgacggtttc aaagtagcgg ttgtcgtcgc tgcgatgctg attggatttg tcgcgattat
     6661 tgcattgatc aatggcattt ttaatgcagt attcggtatt tcgttccaag gcattcttgg
     6721 atatgtgttt gctccattcg cttttcttgt cggtatccca tggaatgaag ctgttaatgc
     6781 gggaagcatt atggcaacaa aaatggtatc gaatgaattt gtcgccatga cgtcgcttac
     6841 gcaaaacggt ttccatttca gcggccgtac aacagcgatc gtatcggtat tccttgtgtc
     6901 atttgcgaac ttctcctcaa tcggaatcat tgccggtgcc gtaaaaggac tgaatgaaaa
     6961 gcaaggaaat gtcgtcgctc gtttcggctt gaaattatta tacggtgcta cgcttgtcag
     7021 ctttttatca gcagcaattg tgggcttgat ttactgaact taatcgaaaa ggatcggtga
     7081 ccaaacatga gaatggtaga tatcatcatc aaaaaacaaa acggaaaaga actcaccact
     7141 gaagaaattc aattttttgt gaacggctat acagatggaa gcattcctga ttatcaggca
     7201 agcgcgcttg ctatggcgat tttcttccag gatatgagtg accgtgaacg cgcggacttg
     7261 acgatggcta tggtgaactc cggtgaaacg attgatcttt ctgccattga aggaattaaa
     7321 gtggataaac actctaccgg cggcgtcggc gacacgacaa cgctcgttct cgctccgctt
     7381 gttgcggctc ttgatgtgcc ggttgctaag atgtccggcc gcggcctcgg ccatacgggc
     7441 ggcacgattg ataagttaga ggcaatcatg ggcttccacg tggaactgac gaaggatgaa
     7501 tttattaaac ttgtgaaccg cgacaaggtt gcggtcatcg gccaaagcgg caatttaacg
     7561 ccggctgata aaaaactgta cgcgcttcgt gatgtaacgg gaacggtcaa ttccattccg
     7621 ctcattgcaa gctcgattat gagcaaaaaa atcgctgccg gggcggacgc catcgtgctt
     7681 gacgtaaaaa cgggagcggg cgccttcatg aaaacagaag aagacgcagc tgaacttgcc
     7741 aaagcgatgg tacgcatcgg aaataacgtc ggccgtcaaa caatggctgt catttcagac
     7801 atgtcccagc cactcggctt tgcgatcgga aatgcgcttg aagtcaaaga agcgatcgac
     7861 acgctcaaag gcgaggggcc tgaggatctt catgagcttg tcttaacgct cggcagccag
     7921 atggttgtgc ttgcgaaaaa agccgataca ttggacgaag cgagagcgaa gctggaagaa
     7981 gtcatgaaaa acggcaaagc acttgagaaa ttcaaggatt tcctgaaaaa ccaaggcggc
     8041 gacagctcaa ttgttgacga tccgtctaag cttccgcaag ccgcatatca aattgatgtg
     8101 cctgccaaag aagcgggtgt cgtctctgaa atcgtcgcgg acgaaatcgg cgtcgcggcg
     8161 atgctgttag gtgccggccg cgccacaaaa gaagacgaaa tcgatttagc cgtcggcatc
     8221 atgctccgca aaaaggtcgg cgacaaagta gaaaaagggg aaccgctcgt aacgctttac
     8281 gctaaccgag aaaacgtcga tgaagtcatc gcaaaagtct atgacaacat ccgcatcgcc
     8341 gcggaagcga aggcgccgaa gctgattcat acgttaatta cagaataaaa aataaagcac
     8401 atcccatgct gagcggggtg tgctttttta attataggat gtgatcggct ggatattcct
     8461 cttggctgat ttttttcgct tttgtaacat ttcttttgaa atggtagatg agatagcaaa
     8521 ggatgataca aggaactccg cagaaaagtg cgattctttg attgggatca aaagcaagac
     8581 cgatacaaga agcagaacat aataagagag cggctatagg cataagagga taaagcggcg
     8641 tgcgaaatgt cagatctttt acatcccccc cttttttcaa aaatctcttt cgaaacaaga
     8701 gttgggacaa ggcaatgctc atccagacca cgactcctgc aaatccagca attgcgacca
     8761 tcaccacata gacagttcca ggggccacga tactggaaac gagagataaa caagatacag
     8821 ccatactgat cattaaggca tttaaaggaa tgcctttaga tgtcactttc ttaaaacggg
     8881 agctgatcat gttttcattt gctaaagacc acatcatacg ggtcgaagca tataagcctg
     8941 agttggcgac agacagcaag gctgttaata ttacgaaatt cataatatca gcagcgtaag
     9001 gaattccgat ctccgcaaat acggcgacaa acgggctttc aatcacgcct gcgtccttcc
     9061 atgaaatcaa ccggataata tgaagacagc gccaatgaaa aaaatcacgg ttctccatgc
     9121 gacattacgg atggatcgcg gtatatcctt ttgaggattt gctgattctc ctgctgtaac
     9181 gccgattaac tctgtaccgg aaaaggcgaa gctcacagat atcatcgcga taaaaacggc
     9241 gagaaagcca tttggaaaca acccgccatg atctgtgaag tttgacaaca taggagcatc
     9301 cgccgttccg tttaaagaga tcaggccaaa catggcggct cctcctaaaa tgataaataa
     9361 aataatggtg acaatcttta cgctggaaaa ccaaaattca gtttccgcaa ataacttaac
     9421 tgaaaatgcg ttgcatataa aaagaagggc tgcaaaaatc gcactccaca tccatacact
     9481 gctgtcaggg aaccagcgct gcatgagaat accggatgcg gtaaactcag agcctaccgt
     9541 caccacccaa ttgatccagt acatgatgcc gaccataaaa ccggtagatg gaccgataaa
     9601 tgttgtagca tatttttgaa aagagccggt caccggcatg gcaaccgaca attcgccgag
     9661 acattgcatg acgaggtaca tcatcaaccc gccgattaca taagcgagta tcgtaccgcc
     9721 gggtccggct tgatgtagcg tatagcccgt actgaggaaa agtcctgtgc ctatgacgcc
     9781 tcccaatgag atcataaata ggtgcctgct tttcattgtg cgttttagct gttggctgct
     9841 gttctcctga agattcactg tctcgccctc cttttagctg ccattcctta ggcagatgag
     9901 tttcttatac ccaaaataca acctgccaga agatcacttg aatgggagag tttcattcct
     9961 tttaatgcgt gtaacagaac atgagctgca gctctgcttg tcatatctcg aaaatcgagg
    10021 gtagggtcga cttcaacaat ttcaatcccg gcaacattgg ctgttgtgcg atgtacttga
    10081 ctgcttcaag caattcgtct gtatagaggc cgcccgggcc aatcgctgga cagccgggtg
    10141 catgggactg gtctaagaca tccatgtcaa cagatataaa aatgaaatct gttttatctt
    10201 gaacaacagg caaaatctct tttatcgttg ggattagtcc tttttcccgg atcatgtcca
    10261 tcgtgtgaat gttcacgtta tgtttttttg catatgcttc ataggcctgg ctgttgctga
    10321 attctctgat acccagctgg atcaaatgtt gaccttcaat gatctcttca tccaaaaggc
    10381 ggcggaaggg ggtgccgttt gtcggccccc gtcctccgta ttgcgaacat cgtgatgggc
    10441 atcaaattga atcaccgctg tcgttccttt tgtttgtgct atcgctttta ttgtggagta
    10501 gctgatagag ttatctcccc caagtatgag cggcacccaa tccggatgat ccgaaagcag
    10561 agcgtgcatg gtttggaaaa tgtgatgatg tgactttacg atatcagtga catgaatatc
    10621 gatatcccca ggtcatatag aagctctgat acgacgtgct ctccaagctc agcagaatag
    10681 gctgatgaat gtttcagagc ctggcgtatt gttccgggtg caaaggaagc gcctgaatga
    10741 ctgatggagg attttgatag ggggacacct atcaacgccg gtcccttaat gtcctggccg
    10801 tcccatgttg cgatcaggtc gctcattttt gtgacatccc ggtctttaaa cgaagatccg
    10861 gcctctctga gaaaagggta cttatccaag aatggctccc tccctgttga caacaattgt
    10921 tccatttttc atgacttgat gtacatgatt gaccccgtag tgatacggaa tatacatata
    10981 gttcggggct tgccaaatga caagatcagc tgagcggcca gctttgagct gaccggcttc
    11041 ttctcctttt cctatggcat atgcggcatt gactgtgacc gcgtgccata tttcttctgc
    11101 agtcattttc agatgaagcg cggcaatgga cataatcagc tggatatttt cagtcggcga
    11161 gctgccagga ttaaaatccg ttgccaagct gacacataca ccttcatcaa tcatagctct
    11221 tgccctggcg tatgtgcttt tgccaagata aaatgtcgtg cccggcaaga ggacggcgat
    11281 cgttcctgcc tcagccaatt tctttatgcc ttcgtccgat gtacctacca aatggtcggc
    11341 tgagacggcc tttagcttac ctgctaattc agcacctcca agcggatcga tttcatctgc
    11401 gtgtattttt aatccgaagc ctgcctcagc tgctttttgt aaataacggc gggattggct
    11461 gactgtaaaa acgcctgttt ctgtaaaaat atcagcaaag ctggcgagct cctgctcttt
    11521 gatttccggc aaaagggaaa gcatttgatc cagaaaatca tctggatcgt tttgatattc
    11581 gggaggaatc gcatgggctc ccataaatgt ggaaacaagg tcaacaggct ggctttcatg
    11641 cagtttcttt gcgacacgca actgtttgag ctctgtctct ttttccaagc cgtagccgct
    11701 tttcacttct gctgtggttg tgccgtagga cagcattctt tgcagatgaa aatgggcttt
    11761 ttgcagcagc tcttcttctg aagccgccct ggtatccttg actgtagaca gaatcccgcc
    11821 gccctgcgcc agaatatcca aatatgaaat gccctgaagc ttaaggttca tctccttttc
    11881 acgagatccg ccaaatacaa gatgggtgtg cggatcaacg aggccaggcg ttacaaggcg
    11941 tcccgaacag tcaatgattt cgtctgcctc gtaaccggct tcagcccctt tttgtccggc
    12001 gaacacaatt ttctgttcat ggatgccgac aacagcgtct tcgatcacat gaagatcctg
    12061 catgcttttg cctgcccgcg gaccgctgct ttccatcgtc aaaagctgac cgatgttgat
    12121 gagaatcgta tcaatttgct ttggcatgtc atcactcctt tatttttgca tcggcacgat
    12181 aatgtcctgt tccttcgcta cttcaacggc acgttcataa cccgcatccg catgacggat
    12241 aatgcccatt cctgggtcgc tcgttaagac ccgcgcgagc cgctcgtcag ccagctcact
    12301 tccatcggcc actgcaacca tgccggcatg aagggaatag cccattccga cgccgccgcc
    12361 atggtggaag gaaacccagc ttgcacccgc cgccgtgttg acaagcgcat ttagcacagc
    12421 ccaatcaccg acagcgtcac ttccatcctt catcgcttct gtttcccggt ttggagaggc
    12481 gacagacccg cagtccaaat gatctctccc aataacgaca ggcgctttta gctccccggt
    12541 tctaaccagc tcgttaatgg cgaggcccat cttttttcgt tctccatatc caagccagca
    12601 gatacgggac ggcaagcctt ggaaggtgac tttttcctgt gccatatcaa tccagcggtg
    12661 aagggcttta tttgtcggga acagctcttt taataacgca tccgtacggt aaatatctgc
    12721 cggatctccg gaaagcgccg cccagcggaa cggccctttt ccttcacaga ataaggggcg
    12781 gatgtaggca gggacaaacc ccggaaaatc gaaggcattc tccagccctt catcctttgc
    12841 gacttgccgg atattgttgc cgtagtcaaa tacaatagag cccttttgct gaaaggccag
    12901 catggcttcg acatgttttt tcatgctttg cttcgcaagg cgcacgtaaa gctctggagt
    12961 gtcttgacgc aaacggtcag cttcatcaag ggaatagccc tcgggaacat aaccgattaa
    13021 agggtcatgg gcagatgtct gatctgtcac aatatcaatt ttgacgcctc ggttcaaaag
    13081 tgtgtgatgc acctcagctg cgtttccgag aagtgcaatg gacaaaggtt ttcctgccag
    13141 ctttgcctct tcagcccaag ctaaggcttc ctcaatcgat gctgtttttc gatcgcagta
    13201 ttttgtttcg atccgcttgt cgatgcgttt ctcgtcaacc tcgacggcaa tcacgacgcc
    13261 ttcattcatc gtgactgaca gcggctgggc gcctcccatt ccgccgagac ccgctgtcag
    13321 cgtcaacgtt ccttttaagc tgcccccgaa gtgctgtcgc gccagctcag cgaaggtttc
    13381 ataggttcct tgcaatatgc cttgtgagcc aatgtaaatc cagctgccag ccgtcatctg
    13441 tccgtacatc attaaccctt ttttctcaag ttcgtggaaa tgctcccagt ctgcccactt
    13501 cggaacaaga acagaatttg ctaggagcac gcgaggggcc tgcgggtgtg tacggaacat
    13561 gccaacgggc tttccggatt gcacgagcaa tgtttcatca ttttttaatg ttttcaagga
    13621 atgctcaatg gcgtgaaaag cgtcccaatc ccgtgcggct ttgccaatcc cgccatatac
    13681 gatgaggtcc tccggcttct cggcgacttc tggatcaagg ttgtttcgaa gcatccgaag
    13741 cactgcctct tgctcccatc ctaagcattc aagctctgtt cctctgttgg cacggattga
    13801 tttttttaca tcagtcatat gttcatcccc cttagttctt tattctgatg atcaggtatt
    13861 aaagattctt tcttcagcca gtcagtcaag cgtcaatgtc ataggaaaaa acacggtcct
    13921 gctgaatgga cggcacgact tttctcattt cttgaaaaag ctgtttcgta taggacgctg
    13981 catgttctat gcctctgtat tcaacagcct gcaatgcgca aatggcttcg atcgcaatga
    14041 ctctccttgt atttgcgatc acctgataag catgccgagc ggcgatggtt cccatgctga
    14101 catggtcctc ttggttggcg gatgacggaa tggaatccac acttgcagga tgggccagtg
    14161 ttttattttc agaaacgagt gaggccgcgg cgtactgcat gatcattgca ccggattgca
    14221 gaccgggatg agggctcagg aacggcggca ggtcattcag ctgcggattc acaagtcgtt
    14281 cgatcctacg ctctgcgata ttcgcaagct ctgatattgc gattttcaga aaatccatgg
    14341 caaaggcgat tggctgtccg tgaaagtttc cgccggaaat cactttgtca ccgtcattga
    14401 aaatgagtgg attgtctgta gctgcgttca tttcaatctc taatttttct ttgacatatc
    14461 ctagtgtctg ccaagtcgca ccgtgtactt gcggaataca gcgcaatgaa taggcatcct
    14521 gtacccgcag ttctccctgg gaggttgtca ggccgctgtc agatagataa aagcgaattc
    14581 gttctgcgac atcgatctgc tcctgatagc cgcgggctaa gtgaatatcc tcgtcaaatg
    14641 catcgataat tccctgcaac ccctcaatcg ttaagctggc aattcgttct gtttgatagg
    14701 ctagtttctc agcttcgatg taggcgacca cccccattgc agtcatggcc tgagtcccgt
    14761 taatcaaggc aagcccttcc ttggatgtca gcgttaccgg ttgaatacct gcttttttca
    14821 agcctgtcat tgccggcatt ctttccccct caaaaaagac ttctccttgt ccgatcagcg
    14881 caagcgccaa gtgggaaagc ggcgccagat ctccgcttgc gccaagtgat ccttgctgag
    14941 ggatgacagg atggacgcgt ttatttaaaa aagcaagcaa ctgctcgatc agctcagcgc
    15001 gtacaccgga aaagcctttt aacagcgcat tggcgcgcaa aagcagcatt gccctggaaa
    15061 cacactcagg aaaagggtcg ccgactccgc aggcatgaga aaggattaaa ttcagctgca
    15121 gcgccgccga gtcttctttc tgaatcagga catcgctgaa tttgccaaat ccggtgttga
    15181 tgccgtagat tgtcttttcg tcgcgtacaa tccgttccac tgctgctctg ctttttttca
    15241 cgcgctccat actttcctca gaagccgctg cctcctcaaa atcaaacagc acacgagcga
    15301 cgtcggctgt tgtcaatgaa gaaccgtcta aagtcaccat aagcccaact cctttttctt
    15361 tactttggta aagcgcccat acaaaaagga gctatgctgt gaacttctgt tttcacgcat
    15421 agccccctat cgtctaagat ctatgggctg tttcatatgt gattaattcc aacgccgaat
    15481 gtttcatgct caagaccttt aatcggcgcc ccgattgttc cgtaaagcga gacagcgatc
    15541 caatcgcctt ccgcttcact ttcataagga tttcccctca aaacggcaaa cctcaatccc
    15601 accgtccgaa gcagcgatcc cagcagcatt tcacctctgg tcacgccatg caaagcctcc
    15661 atcgtcgcat gataaagcgc atgtgactcc cgataaccct cagattgaat gacaccgctc
    15721 tttttggaag cggtttcaat tgcggctact actttatgtg cgtccattga tcctaccttg
    15781 ccaagacaga ccttccatcc gtctcgctcc agctcctcaa cctgcgtact ttcttccgcc
    15841 tcattcagca gcaggagaac agacagccgg ccgatccgac gctctttatg cagtgtcata
    15901 tgaatcactc aattcctaaa aattctgata actattaact gagtattata ttaattggtt
    15961 cagcagcaga agtcaaaagg ttttttatag tctttaacaa gttagattgc tattgtaata
    16021 gcgtgacgca gaaagcagaa caggtttttt cagcgattgc acacgatatc cagacaagga
    16081 ggcaagcgcc gctgtctaac tctcaatatg cgtttactaa gtcgtatttt tcgcaaggcg
    16141 ttttataaag agccagccga atgactctgg tgttgacggg caatcaggca tcatcttaaa
    16201 aaacgccgac aacgaaatgg ctgtatcaca gttgatgcaa aacctgacaa agcagttatt
    16261 acatgtacgc gaaagaaaaa cagacgtgat gcaagaagga gaaacagcaa aagagttgaa
    16321 ctatgaagga gaggatatgc aagcaacaag ttctgcgcaa aacagacaga catcagtctg
    16381 actatgtaag tgaagtgaga aatcacctat ctggatgaat atgaaaacat tcggctgttt
    16441 taataggccg gggtatcttc atagagaaat gtaagcgttt aaaatttaat aaaaaagaga
    16501 ggcgaattgt ttagatgttc aaccgattgt tccgtgtatg ttttcttgca gctcttatca
    16561 tggccttcac cctcccaaac tccgtctatg cacaaaaacc tatatttaaa gaagtcagcg
    16621 tccatgaccc ttccatcatt gaaacaaacg gcacttttta tgtttttgga tctcatctcg
    16681 cttcagctaa atcgaatgac ctcatgcaat ggcagcagct gaccaccagc gtaagcaatg
    16741 acaacccact tatcccgaat gtctatgaag aattaaaaga aaccttcgaa tgggcgcaat
    16801 ccgatactct ttgggcggct gacgtcacgc agctggcgga cggcaaatac tacatgtact
    16861 acaacgcctg ccgcggcgat tcgccaagat ccgccatggg tgttgccgtt gctgacaaca
    16921 tcgaaggccc atacaaaaac aaaggcatct ttttgaaatc aggaatggaa ggcacaagca
    16981 gcgatggaac accgtatgat gcaaccaaac atccgaatgt cgtcgacccg cataccttct
    17041 ttgataaaga cggcaagctg tggatggtgt acggatcata ctcaggcggc attttcatac
    17101 ttgaaatgaa tccgaaaacg ggcttcccgc ttcctggaca gggatatggg aaaaaactgc
    17161 tcggcggcaa ccacagcaga atcgaaggcc cgtatgttct ctacaatcca gacacccaat
    17221 actactactt atacctatca tatggcggtc tcgatgcaac aggcggctac aacatccgtg
    17281 tggcccgctc caagaaaccg gacggccctt actatgatgc agaaggcaat ccaatgctcg
    17341 acgtccgcgg caagggaggc acattcttcg acgaccgttc catcgaacca tacggcgtca
    17401 aactcatggg cagctacact tttgaaacag aaaatgaaaa aggcaccggg tacgtctcac
    17461 caggccacaa ctccgcatac tatgatgaaa aaaccgggcg ttcctattta atcttccaca
    17521 cccgcttccc gggcaggggt gaagaacacg aagtcagagt ccaccaattg ttcatgaaca
    17581 aagacggctg gccggtagca gcaccatatc gttatgcggg cgaaacattg aaagaagtaa
    17641 aacaaaaaga catcacagga acatacaaac ttatccagca cggaaaagac atctcagccg
    17701 acatcaaaca aaccatcaac atccagctca acaaaaacca caccatttcc ggggaaatga
    17761 ccggaacatg gaggaaaacc ggaaaaaaca ccgccgacat cacgttagca ggcaagaagt
    17821 ataacggggt atttttacgc cagtgggatt cggtgagaga gaagaacgtc atgacgttta
    17881 gtgtgctgaa taccagcggt gaggctgtat ggggatctaa ataagatgga gaagcgcctt
    17941 cgagggaagg tgttttttta tgagctttat tgactataag aaacagttaa gtgggaggaa
    18001 aaattagaac tggaggagag attaaaggct taaataaaaa gtccctacta tgattgtttt
    18061 ctcctttcat agggtgatga gatcgtattt ttagcaattt agaaccagtt ctatacctct
    18121 caagacaatc ctttttacct atttatccaa tatgacccat catgtaatat gaaaatagtc
    18181 tgtattgtaa agaatttaca cagtttgata gaaacacgag gtgttgcggc atgcatagtg
    18241 aaatgttgtt acattcggta aaagccgact tacatgaaaa gcaggaacag atccatcaat
    18301 taaaacgagt gctgcacgaa attaggcaaa tcaaacacga tttctctgag gcccagcatc
    18361 tcattcaccg gcctcatctt aaccgggagg catggagagg aacacatgct gagcggtttg
    18421 aagatattcg tgaaggaatg aacaaagcat atcagcaaat caaaagcgat caagtcagcg
    18481 gaatcatcga aagcatagaa ggaaaaatcc actcattaga gggcgatgtg tattctataa
    18541 gacgccaaat cacgaggata gagcatgaaa tagagaagga aaaacataaa aagtgaggtg
    18601 agcacaaatg gcacaggaaa ttaaaatggt gtatgacaca gtgaagcaag ggctttctca
    18661 gctcaagaat tcagctgaac tcaagtcctc attgcccggt catctctcag gcagaaacca
    18721 tttgaatgtt gtgaagtcca tcgagcaatt aaataaggac atcaaagagc tcactgaagc
    18781 atatgcgtct gttctggcca agcatatcgc acaaacggaa agcgcggtaa acgccatgaa
    18841 ggaaacggac gaaaacatat catcttccat gaaataaagc gcgggaggac aagggattga
    18901 aaacattaga tgtccacgct cttcacgagg gcattcagca tacgattgag aaactggaca
    18961 agcaaaaaca acagctggag aagctggaaa aaagcgttga gcatctggca ggcatgaagg
    19021 atgcgctgaa aggaaaaggc ggagatgcca tccggacctt ttacgaggag tgccacaagc
    19081 cttttctcct tttctttggc atatttatcg acgaatacaa aaaagtgctg aaacaaacac
    19141 agcatgcgat ttcctctgta gaatctaact cccacggcat gatcgcagag gcttttctct
    19201 cacacgatgc gagacatggg gtcaagcatg cacgagaagt gacagagcag ctcactgacg
    19261 cagtcaatcg ccagacatca gccatagatc acatcgtcag cctgccgaca gtcaatgatt
    19321 ccttttttcg gatggaaaca gaacaggctg agcggctgat ttcagacacc ctgaataagc
    19381 tctttcaatt tgacggccag caaacccaag cactagaagc cgcaaaatca gattttcaaa
    19441 cgatgaaaaa atacattgat cagctcgaaa ccatgtacac cggcccgaaa attgaaatca
    19501 caggctacaa aagcggctcc atcctgaaat cacaggaaga agaaaacatc aaccaaatct
    19561 tcggcgcgat taacccgcaa atgaagcagg cggatgattc accgatggag atgatgctga
    19621 agaaattagc cgagaatgaa aagtctaaag tggattcagt tgtcaaaacg ggtgattcta
    19681 aaaaggtaag taaaaatatc atcgttatca atggtaaagt gtataatacg agtgaacata
    19741 gagaacatat aaaaactgat ttctcaaatg cagaggttaa gcaagtcgtt tataatgata
    19801 cactttacaa tgtatacata tctggtaatg acatgaagct tgaacctgtc gtctcgcttt
    19861 cggacattaa agtggatgag aatggatatg tgaaaatttt agagacggct gtagaactta
    19921 ccggcgtgta tgatctattt aaagcagcca cgggcagaga tccggtatca ggcgaaaaag
    19981 tcacagggaa agaccgtgtt gttgcctcca taaactcagt accatttgcc aaaatagcta
    20041 agttagaaaa gttaatagat attaataaac ttattaataa tgggaaaaag gctaagaagg
    20101 cttcggaagt taaaaacgtt gctaaggata aagggaaaat tgcgaatgat gtaagtggat
    20161 ctgctaataa aattaattct gatttaataa aaaagtatgc tagagatata gaacaacgca
    20221 caggtagaga attacctaaa aatcaaatag ataaattaaa ggaagcatta agaaataaag
    20281 aatataaaaa aatgtcacca atagagactg caaaacacag gactaaattt gataaagtaa
    20341 aaaataaagt tataaaagaa tgggaagaaa acactggaca aaaatggcct gtttataagg
    20401 aaaatgttgt atctgaaaaa acaggtaaaa ttattagaaa aaaaggggat aagtatgatg
    20461 ctcaccatat aattgaaaat acttttggcg gagaacatga atggtggaat atgcatccag
    20521 caaaatttcc taacgagcat caagctggga ttcatggtac aggctcacca gcaaatgaat
    20581 tatttaaagg aggcaaaaaa aaatgagtta taattttata aaatcaaaca aagaaaatga
    20641 tttttatcca gtgaatcaaa gtgagattga agaggttgaa aaaaatttaa acttaaaatt
    20701 acctagtgaa ttagtgaatt tttatttaga agttggctat gggtttatta aaggatcaga
    20761 gtttaatact aatcgcattt tggatccata ttctgtaaga gactttcgat tgaggataaa
    20821 tgactttgaa ttttatcctg acatagaaat atatgatgag tttgagaatg ataaattaat
    20881 attttttgaa ggtagtgaat cggcattaat gtcaattgaa ttaaatgata ataataaaaa
    20941 tccgatttac tattatgata ttcaaattgc aacttctctt accgagttct taagaaaaat
    21001 agaagagaat gatcagtatt atcttgattt attagatgat gaatgatttt aacattatcc
    21061 cgttacctct cccttaaagg agcaagatga catgttattg atcaataaac agaaggaccc
    21121 tgtttttcag tttttagctg gaacattcca tcaagatatt gaaactcctg atgacgctat
    21181 acaagagtta ttaatagagg aaagtaagga atatttggag gatgctattg tctttttaac
    21241 ggattttatt gaaagtgagc attcagacaa taagaaaaac gattacattc aatcttgcgc
    21301 agatggcgtg tatcttcctg cgtttaattt agaaccaata gattggctaa agaatgtaat
    21361 agtacagata aagaagtctt taaaaaaatt taaacggtaa cgattcataa ccttgattgg
    21421 aaaaaatgcc tttcaaggtt tttaattaca ataatttttt attgaagtta atactaagtt
    21481 caaatcttta tgattacttt tgttctagaa acgatagtca acaccaaaaa tgaaagcgtt
    21541 gacatctcac gaatctagtg ctaaagtata cctacaaaca aataaaacga cccgtcagga
    21601 ttgttactgc gaaagcaggc aaaacctaaa tggtgcaggt gcaggaggag actctcgcaa
    21661 tctgtgtcat ttaggttttt ttattctctt ttaggaggtg atgcagcatt tgatacaaaa
    21721 aaagctggtg aaaggcggcc acctttcatc cagcagtccc cccataaaaa ggaggtatac
    21781 acatggatta tgataaatta tcgaaggaca tattacaact cgtaggcggt gaagaaaacg
    21841 ttcagcgcgt gatccactgc atgacgaggc tgcgttttaa tcttcatgac aacgcgaagg
    21901 cggatcgcag tcagctggag cagctgcctg gagtgatggg caccaatatc agcggcgagc
    21961 agtttcaaat cattatcgga aacgatgtgc cgaaggtgta tcaggcgatt gtgcggcaca
    22021 gcaatctcag tgatgaaaag agcgctggtt catcctctca gaaaaagaat gtgctgagtg
    22081 cggtctttga tgtgatttct ggggtgttta cccctattct gcctgcgatt gcgggagcgg
    22141 ggatgatcaa aggacttgtg gcgctggcag tcacgtttgg ctggatggcg gagaagagcc
    22201 aggttcatgt cattttgacg gctgtcggtg acggtgcgtt ctacttcctg ccgctcctgc
    22261 tagcgatgag tgcggcgaga aaattcggaa gcaatccgta cgtagcggct gccattgcgg
    22321 cggcgatcct gcatccggat ttgacagccc tgctcggtgc ggggaaaccg atttccttta
    22381 tcgggcttcc tgtaaccgct gccacttatt cgtcaacggt catcccgatt ttgctgtcga
    22441 tttggattgc ttcatacgtg gaaaaatgga ttgaccgttt tacacacgca tctctcaaat
    22501 tgattgtggt tccgacattc acgctattga ttgtcgtgcc gctgacattg attacagtcg
    22561 gtccgcttgg cgctatttta ggagaatact tgtcttctgg ggtcaattat ttgtttgatc
    22621 atgcagggct tgtggcaatg attttgctgg cgggtacatt ctctttaatc attatgacgg
    22681 gcatgcacta tgcctttgtg ccgatcatga tcaacaacat cgctcaaaac ggccacgatt
    22741 atttactgcc ggctatgttt ttggcgaata tggggcaggc gggagcatca tttgccgtct
    22801 tccttcgctc tagaaacaaa aaatttaaat cactcgcgct taccacaagc atcacggcgc
    22861 tgatggggat cacagaacct gcgatgtacg gcgtgaatat gcgattgaaa aagccgtttg
    22921 cggccgcttt gattggcggt gcagccggtg gcgcgtttta cggcatgacg ggtgttgctt
    22981 cctatatcgt cggggggaat gcaggtctgc cgagcatccc tgtctttatc ggcccaacgt
    23041 ttatttacgc gatgatcggc cttgtgattg cgtttgcggc gggaacagca gctgcgtatt
    23101 tgcttggatt cgaggatgtg ccttctgacg gcagccagca gccggcagtg catgaaggca
    23161 gcagagagat cattcacagc ccgattaagg gagaagtgaa agccttaagt gaagtcaaag
    23221 acggagtgtt ttctgctggg gtcatgggaa aaggatttgc cattgagcct gaagaaggag
    23281 aagttgtttc gcctgttcgt ggaagcgtta ccaccatttt taaaacaaaa cacgcaattg
    23341 gcattacgag tgatcaggga gctgaaatac tcatacacat tggattggac acggtaaagc
    23401 tggagggaca atggttcacg gctcacatca aagaaggcga caaggtcgca ccgggagatc
    23461 cgctcgtgtc ctttgatctg gagcaaatca aagccgcggg atatgacgtc attaccccgg
    23521 tgattgtgac caacacagac caatattcgt tttcgccggt gaaagagatc ggtaaagtgc
    23581 agccaaaaga agcgctgctt gctttatctt gaaaaaacta atggggtgat caatatgagt
    23641 tcaaatgaaa aacgatttcc agaaggattt ttatgggggc ggcgcagttg ctgccaacca
    23701 agtggagggt gcttataacg agggtggtaa ggggctttcg acagctgacg tatcgccgaa
    23761 cgggatcatg tctccatttg atgaatcaat gacttccttg aatctgtatc acaacgggat
    23821 tgacttttat catcgttata aagaggatat cgccttattt gcagaaatgg gatttaaggc
    23881 gttccgcaca tcgattgcgt ggacgagaat ttttccgaat ggcgatgaag aggagcccaa
    23941 tgaagaaggc ctcagatttt atgatgatct gtttgatgag ctgttaaagc atcatattga
    24001 gcctgtcgta accatctctc attatgagat gccgctcggt ttagtgaaaa attatggcgg
    24061 ctggaagaat cgcaaagtca tagagtttta tgaacgctat gccaaaacgg ttttcaaacg
    24121 ctatcaacac aaagtgaagt attggatgac gtttaatgaa attaacgtag tgctccatgc
    24181 gccatttacc ggaggcggtc ttgtttttga agaaggagaa aacaaattaa acgcgatgta
    24241 ccaggcggca caccaccaat ttgtggccag tgctcttgct gtcaaagcgg gtcacgacat
    24301 cattcctgat tcgaaaatcg gctgtatgat agcggcaacg acaacctatc cgatgacttc
    24361 taagccggag gatgtcttcg cggcaatgga gaatgagcgc aaaacacttt tcttctcaga
    24421 tgttcaggca agaggcgcat acccgggata tatgaaacgc tatctggcag aaaacaatat
    24481 tgaaattgaa atggctgaag gcgatgaaga gctcttgaaa gaacatacgg tggattatat
    24541 tggatttagc tactacatgt cgatggcggc gagcacagat ccggaagagc ttgcaaaatc
    24601 agggggcaac ctgctgggcg gagtcaaaaa cccttacctc aaatcatcag aatggggctg
    24661 gcagattgat ccgaaaggct tgcgcatcac gctcaacacc ttatacgacc gttaccagaa
    24721 gccgctgttc atcgttgaaa acggccttgg cgctgtagac aaggttgaag aggacggcac
    24781 gattcaggac gattacagaa tcaactatct gcgtgatcat ttaattgaag cgcgcgaagc
    24841 cattgcggac ggcgttgaat taatcggata cacatcatgg gggccaattg accttgtcag
    24901 cgcatctact gcggaaatga aaaagcgcta cggcttcatt tatgtagacc gggacaatga
    24961 aggaaatgga acatttaacc gcatcaagaa aaaaagcttc aactggtatc agcaggttat
    25021 cgccacaaac ggagagagtc tctgacaatt ttttgaaaac tcatgcgctt caattgacaa
    25081 taacgaaatg caggcggaca ataaaagaga aagatgaacc acccacagtc cgaaaggcgg
    25141 gaagagcatg tttaacaaaa tgttagtagc gattgacgga tcagacatga gtgcaaaagc
    25201 gcttgatgcc gcagtgcatt tggcaaaaga gcaacaagcg gaactaagca ttcttcatgt
    25261 ggggagagaa gccgtcgtca cgacttcttc tctgacggga attgtctatg tgcctgaaca
    25321 ctttattgat gaaatcagga
//
