LOCUS       gnlProkkaAODEHLID_90   13601 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AODEHLID_90.
ACCESSION   gnlProkkaAODEHLID_90
VERSION     gnlProkkaAODEHLID_90
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 17:52:50
            Original ID  :: gnl|Prokka|AODEHLID_90
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 30350
            Orig. end    :: 43951
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13601
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:10351]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10351
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..13601
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13601
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             2126..3160
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg55_20"
                     /sec_met_domain="PF04055 (E-value: 3.3e-18, bitscore: 57.7,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKYPLLGMTLVELQSLTKRLGMPGFAAKQIASWLYEKKVASIDD
                     MTNLSLKHRELLKQNYEVGAEAPVDEMRSVDGTVKYLYKVGENHFVESVYIPDDDRATL
                     CVSSQVGCKMNCKFCMTGKQGYTANLTASQIMNQIHSLPERDKLTNVVMMGMGEPLDNL
                     DEVLKALELLTATYGYAWSPKRITLSTVGLRKGLQRFIEENDCHLAISLHSPLTVQRAE
                     LMPAEKAFSITEMVELLKNYDFSKQRRLSFEYIVFKGLNDSQVYAKELLKLLRGLDCRV
                     NLIRFHAIPGVDLEGADMDTMTRFRDYLTSHGLFTTIRSSRGEDIFAACGMLSTAKQEK
                     NNES"
     CDS             3179..4219
                     /locus_tag="ctg55_21"
                     /transl_table=11
                     /translation="MKKYSFILCIALVAFVVASCGLKGNHTSSGRAYELLVVVDHGVWD
                     RAAGRALHDALDADMPGLPQSEPSFRIMYTSPKDYDSTLKLIRNIIIVDIQDIYTKASF
                     KYAKDVYANPQMILTIQAPNEEEFEKFVEENKKTIVDFFTRAEMNRQITFLEGKHSNFI
                     SQKVDSLFGCDIWVDAELANSKTGDDFFWASTNTGSADRNFVMYSYPYTDKDTFTKEYF
                     VHKRDSVMKANIPGFKEGVYMSTDSLLTDVRPINVQNSYTMEARGLWRMKGDFMGGPYV
                     SHTRLDEKNQRIITAEIFVYSPDKMKRNLVRQMEASLYTLKLPNEVQQKQIPLGEASKE
                     AEQTNK"
     CDS             4224..5318
                     /locus_tag="ctg55_22"
                     /transl_table=11
                     /translation="MEDNKIRIGITQGDINGVGYEVILKTFSDPTMLELCTPIIYGSPK
                     VAAYHRKALDIQANFSIVNSATEAGYNRLSVVNCTDDEVKVEFSKPDPEAGKAALGALE
                     RAIEEYREGLIDVIVTAPINKHTIQSEEFSFPGHTEYIEERLGNGDKSLMILMKNDFRV
                     ALVTTHIPVREIATTITKELIQEKLMIFHRCLKQDFGIGAPRIAVLSLNPHAGDGGLLG
                     MEEQEVIIPAMKEMEEKGILCYGPYAADGFMGSGNYTHFDGILAMYHDQGLAPFKALAM
                     EDGVNYTAGLPVVRTSPAHGTAYDIAGKGVACEDSFRQAIYVAIDVFRNRQREKVARAN
                     PLRKQYYEKRDDSDKLKLDTVDED"
     CDS             5328..6569
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 390.2; E-value:
                     2.3e-118)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg55_23"
                     /transl_table=11
                     /translation="MTKAEIQQVKQRFGIIGNTEALSRAIDVAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EADGGTIFLDEVGELPMSTQARLLRVLESGEFMKVGSSKVQKTDVRVVAATNVNLTQAI
                     AEGRFREDLYYRLNTVPIQIPPLRERGDDVLLLFRKFSADFAEKYRMPAIQLTEDAKKE
                     LLAYPWPGNVRQLKNITEQISIIETNREISAAILQNYLPAQNTQRLPALMGTRESKGFE
                     SEREILYSVLFDMRQEVAELKKMVHNLMAERAGQVGQVGQMGTVVTTPVVTAHQPSVPA
                     IIHTMQPTVCKDDDDIQDTEEYVEESPLSLDEVEKEMIRKALERHHGKRKSAAKDLNIS
                     ERTLYRKIKEYELD"
     CDS             6556..7083
                     /locus_tag="ctg55_24"
                     /transl_table=11
                     /translation="MNWIKKIIRPLLLFGLPLVVIACTVSYKFNGSSINYDKVKTISIA
                     DFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPNQNADLQIDGEITGYNQYNQAVS
                     ADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTYDSSQLLTAVQDGLIAEMSKEI
                     TDQIFNATVANW"
     CDS             7089..7862
                     /locus_tag="ctg55_25"
                     /transl_table=11
                     /translation="MTSVNFQQWIQHPETLNRDTLYELRNLLARYPYFQSLRLLYLKNL
                     YILHDISFGGELRKAVLYIADRRQLFRLIEGDRYDVQARKKGVPLTEVLKDEPSVDRTL
                     ALIDAFLSTVPEEVTARTSFDYSMDYTSYLLEETPATEQPAEETPKLKGFELIDDFIEK
                     SESDSPLCMKPLREEMPSSPTSSDELTEEETMKEEEEDDSCFTETLAKIYVKQQRYSKA
                     LEIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
     CDS             8049..8264
                     /locus_tag="ctg55_26"
                     /transl_table=11
                     /translation="MVVMSIATAYVVPRSAVAKDAVLEQAQKEQQTNPYNLPAGTAAPQ
                     TEAPATNAPATETPAPATETPAPAAE"
     CDS             8515..9903
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 92.3; E-value: 4.1e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg55_27"
                     /transl_table=11
                     /translation="MTEHLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AISTTFPEGAMLFGFKTQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGTFHTNIPAPILFCLIMLCVGTIAFFLYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMIIGSVMLIFVHTMFAL
                     PILNIWWFATIIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNTYCKGPVVDGAQTYDYTLPMTIFALFGVLALIVALMLKAENKKKGYGLEEA
                     NIQK"
     CDS             10001..10351
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg55_28"
                     /sec_met_domain="PqqD_RRE (E-value: 2.4e-11, bitscore:
                     34.4, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 8.7e-18, bitscore: 55.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAKEKINLLEVIPCRSEHITAEREGETIVLSFPRFKYPWMQRFL
                     VPKGMSKELHVKLEEHGTAVWELIDGKRNVREIIEKLADHFQNEEGYESRVSAYLSQMQ
                     KDGFIKLVIPVV"
     CDS             complement(10370..10654)
                     /locus_tag="ctg55_29"
                     /transl_table=11
                     /translation="MVGEGHAFDMIRRIKEGREASRLRRERANDKLKHLNRANEPYPLP
                     NTTPEEMERIIHDSEKKKEKDSNYFVWGTLIIMGVLIAIAVILWAVFIK"
     CDS             complement(10691..11758)
                     /locus_tag="ctg55_30"
                     /transl_table=11
                     /translation="MKKLIIAAGLLMTTSAYAQTEVLTGVTRGKDYGVVYSLPKTQIEL
                     EIKANKVNYTPGEFSKYADRYLRLTNVSADPEEYWELASVKVKSVGVPNSETTYFVKLK
                     DKTVAPLMELTEDGIVKTINVPYSNSSAGKKAAPAPAVLQKKANPREFLTEEILMASST
                     AKMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNAQEEAMTQMFSGTCN
                     KEERTFTVRLTPDKEFNNEVAFRFSKKLGVVANNDLAGTPFYISLKDLKSVKIPQEDGK
                     KKKDLDGIAYNVPGQAMVTLTDGKKKLYEGELPITQFGVIEYLAPVLFNKNSTIKVYFD
                     PNTGGLLKVDREEGK"
     CDS             complement(11831..13342)
                     /locus_tag="ctg55_31"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIENEPIASIDLMERAATVLTKAITDRWNT
                     ETPVTIFAGPGNNGGDALAVARMMAEKGYKIEVFLFNTKGELSPDCQTNKELVEMMEEV
                     KFHEISTQFVPPALTPDHLVIDGLFGSGLNKPLSGGFAAVVKYINSSPAMVVAIDIPSG
                     LMGEENTFNVKANIIRADVTFSLQLPKLAFLFAENTEFVGEWEVLDIQLSEDGIEEMET
                     NYEMLEIEQIRSLIKPRKQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPMCNNDILQTSIPEAIVETDINETCFAVPTDTDDYQAVGIGPGLGRNEETEAALLEQ
                     LEHCQTPVVVDADALNILANHRHALTHLPKGSILTPHPKELERLTGKCQDSYERLMKAC
                     ELARAAHVHIILKGAYSAIITPEGKCFFNPTGNPGMATGGSGDVLTGVILALLAQGYPT
                     EEAAKIGTYIHGLAGDVAQKKQGMIGMIASDIITCLPTAWRLVSE"
     CDS             13524..13601
                     /locus_tag="ctg55_32"
                     /transl_table=11
                     /translation="MQHHYELTFISPEKDFWFFVKFGGTS"
ORIGIN
        1 gctcatttcc agttgaatgg tttttcgcag gcggatgcca agtcgttctc aaagcaatat
       61 ttgtctactt actccaaggc tttgtccgca caacaggaag atattcttgc ttcgtgggtg
      121 ctggctaaac aaccgcgctg tttaagtgta ttgctcaacg agctggtttc attcggtcag
      181 tacgatgctc tcaatgaata tatgagtgga tattgccggc tcaatgaggt tgggcaattc
      241 tatgacagtg tgcttcggcg tttgtcggct gattatggtt tcgaagagat tggaagaacg
      301 cttctgatgc tttcacttac tttagaagga tttaccgaag atgaagtgaa gagcatggca
      361 gacattaatc agatactttg gtcgcagttg agagtggaaa tgagcagctg gctcaccaac
      421 aaaggagggc gatattgcat tggtgacaca caaatggtag aggcaatcga acgctatttc
      481 gctcaagatg acgaatgtat agatgatagt cgccatgaaa ttatttccgc tttgctggat
      541 gaggaagaga ttctttccca tccgttgact tttgccgatt ataactatcg catgaaacag
      601 ttctgctacc atgattcgta tcgctataaa gtggagatta cctatcaatg ctataagatg
      661 caagaatggg atatattgaa ggattggatt tgtgatgtgg agattttcga gattctgtat
      721 cgcacgaatc gttctctgtt ggaagatagc tggaaggcga tcatgaacga caatcctgaa
      781 gttacgcctg aagtctatgc cgaattggac tttgatgaga tcgattcttt tttaattcct
      841 gtcattgcta atgatatggc tactttcttg agcagttctt tccatctgac gaaggcggca
      901 gctgctgtga gtgagaagag tatggaaggt gctgccatgc cactcattgc caagtcggta
      961 ttgaagatga atgagggatg ccggtatgcc cgtaatgaag aatacgaaac ggcatgcgac
     1021 tgttttctga aagcattggt gatgcaggaa aacattgtac cgactccgga actggagatt
     1081 gccaacacct gccgaaatct agctctggca tattactaca atgagcaata caatgaagca
     1141 gtgacctatt tgaatagggc gcttgattat catgcggctt ctgctgatga gaagagtcag
     1201 gcagaagtca ttgaactttc cgaatatctg gcttattgtg attactataa ggatgaggaa
     1261 gagagtgctg ccgagaaatt ccggaaagta gctgaaatgc acgagtcgtt gaatggtagg
     1321 ctgtccggtg gagtggctaa atgtttgcgt atgcagggta aatgtcttta ttatatcaaa
     1381 cgatacgatg aagcatggat gctgatgaat caggcgttgg acattgctat acagatagac
     1441 agcaaaaaac agatcgtcgc ttgtcataaa cagttgtatt atctatgcag ggaattcaaa
     1501 cggatgatga atgaacgtgg cgatgagcag gcgtctactt tattcttccg tgagtctctt
     1561 ctgcatgaaa tgtatttcag cgaaaaaccg cgtctggcgg aactgactgt ccgctacgag
     1621 gcattgagat gtgatattat gcagcagtat tacatgaata aagactatga taacgtgatt
     1681 cgtattgcaa cgtctttgga ttttcacgat gatgctgacc ctaatgcttc ctgtctggta
     1741 tattattaca aagcacaggc ttatgtgaag ttggagaatt atccaatggc gaaagaggct
     1801 ttcttcagag aacttgaact gcgaaagaag tatttgggat gggaggaaga agatacgatt
     1861 ctggcttgtc agaacctagg ggttttgcac agcttttgta atgaacggga agaggcgctg
     1921 gcttgtttcc gtgaggcgta cggtcatgaa gtgaaaaaga atggcgagga ttctgaaatg
     1981 gcgcaaaagc tacttcaata tatcagcgtg gttgaatcat aacggaggca tacttccctt
     2041 ttttgttaac ttttacattc ctgctatacg gaaatcgact ttatttcctt acatttgcag
     2101 atataaacta tcaacagaaa gaagaatgtc taaatatccc cttttaggaa tgactcttgt
     2161 agagcttcaa tcattgacaa aaagactggg tatgcccggc tttgctgcca agcagattgc
     2221 atcctggctt tacgaaaaga aggtagcctc gattgatgat atgactaatt tgtcattgaa
     2281 acaccgggag ttgctcaagc agaactatga ggtgggagcg gaagctccgg tagatgaaat
     2341 gcgctctgta gatggtacgg tgaagtatct ttataaagtg ggtgagaacc attttgtaga
     2401 gtcggtttat ataccggatg atgaccgggc aacgttgtgc gtgtcgtcac aagtaggttg
     2461 caagatgaac tgtaagttct gtatgaccgg taaacagggg tataccgcta acctgaccgc
     2521 cagccagatc atgaatcaga ttcattcgct gccggaacgg gacaaactga ctaatgtcgt
     2581 aatgatggga atgggcgagc cgctcgataa cctggatgag gtattgaagg cattggaact
     2641 actgaccgct acctacggtt acgcatggag tccgaagcgt atcacgcttt ctactgtcgg
     2701 gctacggaaa ggattgcagc gttttattga agaaaacgac tgccaccttg ccatcagcct
     2761 tcactctccg ctgaccgttc agcgtgctga attaatgccg gcggaaaagg cgttttcaat
     2821 caccgaaatg gtggaactgt taaaaaacta tgattttagt aaacaacgtc gactttcgtt
     2881 tgaatatatt gtttttaaag ggctcaatga ttcgcaggtc tatgccaaag agttgctgaa
     2941 acttcttcgc gggctggatt gcagggtgaa tctgattcgt tttcatgcca taccgggggt
     3001 agaccttgag ggggcggaca tggatacgat gacccgtttt cgtgattatc tgacatcaca
     3061 cggacttttc accactatcc gttcatccag gggcgaagat atttttgccg cttgcggtat
     3121 gctgtcgaca gcgaaacagg agaaaaataa tgaaagttaa tatataaaac cgaacatcat
     3181 gaaaaagtac tcttttattt tatgcatcgc tttggtagcc tttgtcgttg catcttgtgg
     3241 tctgaaagga aatcacacct ctagtggtcg tgcttacgag cttttggttg tagtagatca
     3301 cggtgtttgg gatcgtgctg ccggaagggc tttacatgat gcgctcgatg ctgatatgcc
     3361 cggtttgccg cagtcggaac cttctttccg gattatgtat acttcgccga aagattatga
     3421 ttctacgctg aagttgatac gtaacattat tattgtagat atacaggata tatatacgaa
     3481 agcctcgttc aaatatgcga aggacgtgta tgccaatccg cagatgatat tgactatcca
     3541 ggctccgaac gaagaagagt ttgagaagtt tgtggaagag aacaaaaaga cgattgtcga
     3601 cttctttacc cgtgcggaaa tgaaccgtca gattacgttc ctggaaggga agcatagtaa
     3661 cttcatttcg cagaaagtgg acagtttgtt cggatgcgac atctgggtgg atgccgaact
     3721 ggctaattca aagaccgggg atgatttctt ttgggcttct accaacacag gtagtgccga
     3781 ccgtaacttt gtgatgtact cttatccgta cactgacaag gatacgttta ccaaagaata
     3841 ttttgtgcac aaacgtgact ccgtgatgaa agccaatatc cccggattca aggaaggcgt
     3901 ttatatgtca accgatagtt tgctgaccga tgtccgtccg atcaatgtgc agaacagcta
     3961 cacaatggaa gcacgtggcc tgtggcgtat gaagggcgac tttatgggtg gtccgtatgt
     4021 atctcatact cgtctggacg agaaaaacca acgaattatt acagcagaaa tatttgttta
     4081 ttcacctgat aaaatgaaac gcaacctggt acgccagatg gaagcatctc tgtatacact
     4141 gaaacttccg aatgaagttc agcagaagca gattccattg ggagaagcat ctaaggaagc
     4201 ggaacaaact aataaataaa aacatggaag ataacaagat aaggataggt atcacccaag
     4261 gagatattaa cggggtgggc tatgaggtga ttcttaagac attttccgac cctacgatgt
     4321 tggaactatg tactccgatc atttatggct caccgaaagt agcggcttat catcgcaaag
     4381 cgctggatat acaggctaat ttcagcattg tcaactctgc taccgaagcg gggtacaacc
     4441 gtttgagcgt ggtgaactgt acggatgatg aggtgaaagt ggaattttcc aaacccgacc
     4501 ccgaagccgg taaagctgcg ttgggggctt tggaacgtgc catcgaagaa tatcgcgaag
     4561 ggttgataga cgttatcgta acagctccga tcaacaaaca tacgattcag tcggaagagt
     4621 tctccttccc cggacatacg gaatatatcg aagaacgtct gggcaatggt gataagtcat
     4681 tgatgatttt gatgaagaat gacttccggg tggctttggt tacgacacat atccctgtca
     4741 gagagatcgc gactacgatt accaaagaac tgattcagga gaaactgatg atattccacc
     4801 gttgcctgaa acaggatttc ggtatcggcg ctccgcgtat tgcggtgctc tctctcaatc
     4861 ctcatgccgg agacggtggt ttgttgggaa tggaagagca ggaagtgatt atccctgcca
     4921 tgaaagaaat ggaagagaaa ggaatccttt gctacggtcc ttatgcggcc gacggcttta
     4981 tgggttcagg caattatact cattttgacg gtatcctggc gatgtatcac gatcagggac
     5041 tggctccgtt caaggccttg gctatggaag acggggtgaa ctatacggca ggcctgccgg
     5101 tagtacgtac ttctccggct catggaacgg catacgatat tgcaggcaag ggagtggctt
     5161 gtgaagattc tttccgtcag gcaatctatg ttgccatcga cgtgttccgt aatcgtcagc
     5221 gggaaaaagt ggctcgtgcc aatccgttgc gtaaacagta ttacgagaaa cgtgacgata
     5281 gtgataaact gaagctggat acagtagacg aagattaaaa acgagtgatg acgaaagcag
     5341 agatacaaca agtgaaacag cgtttcggta ttattggaaa tactgaagca ttgtcgcgcg
     5401 ccatagatgt tgccattcag gtagctccta ccgatttgtc tgtgctgatt accggagaaa
     5461 gtggagtcgg aaaagaaagt tttccgcaga ttattcatca atatagccgg aggaagcacg
     5521 ggcagtatat tgctgtcaac tgtggcgcta ttccggaagg tacgattgat tccgaactgt
     5581 tcggacatga gaaaggtgcg tttaccggtg cgattggcga acggaaaggg tactttggcg
     5641 aagccgacgg cggtactatt tttcttgatg aagtagggga gttgccgatg tctacccagg
     5701 cacgtttgct ccgtgtactg gagagtggcg agtttatgaa agtaggttcg tccaaagtac
     5761 aaaaaacgga tgtgcgtgtg gtggcggcta ccaatgtcaa tctgacacaa gcgattgcag
     5821 aaggacgttt ccgtgaagat ttatattacc ggttgaatac ggtgcctatc caaataccgc
     5881 ctttgcgtga acgtggtgac gatgtacttt tgttgttccg taagttttcc gcagactttg
     5941 cagagaaata ccggatgcct gctattcagt tgacggagga tgcgaagaaa gagttgttgg
     6001 cttacccgtg gcccggaaac gtgcgccagt tgaagaacat caccgagcaa atatctatca
     6061 ttgaaaccaa cagggagatc tctgctgcta tcttgcagaa ttatcttcct gcacaaaata
     6121 cgcaacgtct tcccgcgttg atgggaacgc gtgagagtaa aggctttgag agcgaacggg
     6181 agattcttta ttccgttctg ttcgatatgc gccaggaagt ggcggagctg aagaagatgg
     6241 tgcacaacct gatggcggaa cgtgccggac aggtggggca ggtaggacaa atgggaacgg
     6301 tggttactac tccggtagtg acggcgcatc aaccttcggt acctgctatt attcacacca
     6361 tgcagcctac ggtttgcaag gatgatgatg acatacaaga cacggaagaa tatgtagaag
     6421 aatctccttt gtcactggat gaagtggaga aagaaatgat acgcaaggca cttgagaggc
     6481 atcatggaaa gcggaagagt gcggccaagg acttgaatat ttccgagcgt acactttata
     6541 gaaaaataaa agaatatgaa ttggattaag aaaataatac gccctttgtt actgttcggc
     6601 ttgccgttgg tagtcattgc gtgcactgtt tcctataagt ttaacggatc gtctatcaat
     6661 tatgataagg taaagaccat ttcgatagcc gacttcccga tcaagtcgga gtatgtatat
     6721 gctccgttgg caaccaaatt caatgaggac ctgaaagata tcttcatccg gcagacccgt
     6781 ctgcaactgc tcaagccgaa tcagaatgcg gacttgcaga ttgacggaga aatcacagga
     6841 tacaatcagt acaaccaggc agtatctgcc gacggttatt cttcggagac gaagttgact
     6901 attaccgtca atgtacgttt tgtcaacaac accaatcatg ccgaagactt tgaacaacag
     6961 ttttctgcgt tccgtaccta cgactctagc cagttgctga ctgccgtaca ggacggattg
     7021 attgctgaaa tgtctaaaga gatcaccgac caaattttta atgcaactgt agcaaactgg
     7081 taatataaat gacttctgtt aactttcaac aatggattca gcatcccgag acgctgaata
     7141 gggatacttt gtacgaactg cgcaatcttc ttgcgaggta tccgtatttt cagtcacttc
     7201 gtctgctgta tctgaagaat ctgtatattc tccatgatat tagtttcggt ggagaactgc
     7261 ggaaagcagt tctttacatt gcagacagac ggcagttgtt ccggttgatt gaaggtgacc
     7321 gctatgatgt gcaagcacgg aaaaagggag tacctctcac ggaggtactg aaagacgaac
     7381 cgtccgtaga ccgcacatta gcattgatcg acgctttctt gtccacagta cccgaagagg
     7441 tgactgcccg caccagcttc gactattcga tggattacac ttcttatctt ttggaagaga
     7501 ctccggccac ggaacagcca gccgaagaaa cgcccaaact caaaggcttc gaactgattg
     7561 acgactttat agaaaagagc gagagcgact ctcccctctg catgaaacct ttaagagaag
     7621 aaatgccatc ttcgccaacc tcttcggacg aacttaccga agaagaaacg atgaaagaag
     7681 aagaggaaga tgacagctgt tttacggaaa ctttggcaaa aatctatgtt aaacagcaac
     7741 gatattcaaa agctcttgaa ataattaaaa aattaagctt gaaatatcca aaaaaaaatg
     7801 cttactttgc agaccaaatc agatttttgg agaaattgat tattaacgct aattcaaaat
     7861 aactaaaaat gtacttatta ttcgttatct taatggttat tgcagccttg ttgatgtgtt
     7921 tcatcgtgct gattcagaac tcaaaaggag gcggacttgc ttctggtttc tcttcatcta
     7981 acgccatcat gggcgtgcgc aagactacag attttctgga aaaagcaaca tggggcttag
     8041 ctatcttcat ggtggtaatg agcattgcta ctgcttatgt agttcctcgc tctgctgttg
     8101 ctaaagacgc agtgttggaa caggcacaga aagaacaaca gactaacccg tataacttac
     8161 ccgcaggtac ggctgcgccg caaactgaag ctcctgctac caatgcacct gctacagaaa
     8221 ctccggcacc ggctactgaa actcctgctc ctgcagcaga gtaattcact ccgtcgtcag
     8281 gtaagacttt gggggtaaaa ccattaatgg gaaggtgcag acggatgctg catttctttg
     8341 atatttaagt gcggattacg cagattacac ggattttcaa tcttccgtgt ggtcagtgta
     8401 atccgcactt aactttttct tgtaaaaaca atctcttttt gatagaaaca aacgagattt
     8461 aactaccttt gttggtcgta tgaagattat taactactat ttttaaatat aacaatgaca
     8521 gaacatttga aacagaaatt gaatgactcc gccgtactcc gatggagtgt tctagcatta
     8581 gtcgcattta ctatgctatg cggctatttc ctcaccgacg taatgtctcc tctaaaaccc
     8641 atgcttgaga aagaactact atgggacagt cttgattatg gtttcttcac aagcgcttac
     8701 gggtggttta atgtattcct attgatgctg attttcggtg gtatcatttt ggataagatg
     8761 ggagttcgtt tcaccggaat gggggcttgc ttattgatgg tgtttggttg tggattgaaa
     8821 tactatgcga tttctactac ttttccggaa ggtgccatgc tcttcggatt caaaacacag
     8881 gtaaccctgg ctgcattggg gtatgctatc ttcggtgtag gtgtggaaat tgccggtatc
     8941 acagtttcca aaattatcgt gaaatggttc aaaggtaagg aaatggcatt ggctatggga
     9001 cttgaaatgg ctacggcacg tattggaaca actctggcaa tggtgcttac ggttcctttg
     9061 gccgactttt tcggatctac ggatgagagt ggcacattcc ataccaatat tcctgctccg
     9121 attctgtttt gtctgattat gttgtgcgtg ggtacgattg ctttcttcct ttatactttc
     9181 tatgataaga agttggatgc ttctttggat gcagagggat tggaaccgga agagccgttc
     9241 cgtatgaaag atattgtgta tatcattacc aataaaggat tctggctgat tgcattacta
     9301 tgtgtattgt tctactcggc tgtattcccc tttatcaagt atgctgccga cttgatggtg
     9361 cagaaatata acgtagatcc gaagttggcg ggaacgattc ccggattgtt gccgattggt
     9421 gcgattattc tgactccgtt gttcggctcg ctttatgacc gtattggtaa gggagccaca
     9481 ttgatgataa tcggatcagt gatgcttatt tttgtgcata cgatgtttgc tctgcctata
     9541 ctgaatatat ggtggtttgc tactattatc atgattatat tgggatttgc cttctcgttg
     9601 gtgccttcag ctatgtggcc gtctgttccg aagattattc cggaaaaaca gttgggtacc
     9661 gcatacgcat tgattttctg ggtacagaac tggggattga tgggtgttcc tttgttgatc
     9721 ggatgggtgt tgaatactta ttgcaaaggt ccggtagtag acggtgcaca gacttatgac
     9781 tacacgttgc cgatgactat ttttgctctt tttggtgtac ttgctctgat tgtggctttg
     9841 atgttaaagg cagagaacaa gaagaaggga tacggtctgg aagaggcgaa tattcaaaag
     9901 taactgggaa attcaatacc taaagtaaca aaggaatttt gtatcaaggt gtaaacaaaa
     9961 gggtatcagt atgaatactc tgaaataaaa aataagaagt atggctgcca aagagaaaat
    10021 caacctgtta gaggtcattc cctgtcgcag tgaacatatt acagcagaaa gggaagggga
    10081 gacaattgtg ctctcctttc cccgttttaa atatccgtgg atgcaacgct tccttgtgcc
    10141 gaaaggaatg tcgaaagaac ttcatgtgaa attggaagaa cacggtacgg ctgtatggga
    10201 actgatagat ggaaaacgca atgttcgtga gattatagaa aaactcgcag accactttca
    10261 aaatgaagag ggctacgagt cgcgtgtatc ggcttatctt tctcaaatgc agaaagatgg
    10321 atttataaaa ctggtgatac cagtcgtata aataggaact tattattatt tatttgataa
    10381 atacagccca aagtatgacg gcaattgcta tcaggacccc catgataata agcgttcccc
    10441 aaacaaaata attgctgtct ttctctttct ttttctccga gtcgtggatg atacgttcca
    10501 tttcttcggg ggtggtgttg ggtagtggat aaggttcgtt tgcacggttt agatgcttca
    10561 acttatcgtt agcacgttca cgacgtaggc gggaagcttc ccgtccctct tttattcggc
    10621 gtatcatgtc gaatgcatgt ccttcaccaa ccatattctt tgttttttag aagttcactt
    10681 cctcgttttt ctatttccct tcttctctgt ccactttgag caatcctccc gtatttggat
    10741 caaaataaac tttgatggta gaattcttgt tgaacaaaac cggagccaga tattctatca
    10801 caccaaattg agtaatagga agttcacctt cgtaaagttt ctttttgccg tcggtcagtg
    10861 taaccatagc ttgtccgggt acgttgtagg cgattccatc caaatctttc ttcttcttac
    10921 cgtcttcctg tggtatcttg accgatttca ggtctttcag actgatataa aacggagttc
    10981 ctgccaaatc attgttggca actacaccta acttcttcga gaagcggaag gcaacttcat
    11041 tgttgaattc cttgtcaggg gtaaggcgga cagtgaatgt tctctcttct ttgttgcagg
    11101 tgccggagaa catttgtgtc atggcttctt cctgtgcatt cagattgtcg agcataatct
    11161 taagctgtgc cccatctgaa ggcatattat cagcttgtcc gcgcaataag gcatttttgc
    11221 tttcgcggat gttatagatt tctttagcca ccagctcggc catcttggcg gtagaactag
    11281 ccatcagaat ctcttcggtc aggaattcgc gaggattcgc tttcttttgg aggactgcgg
    11341 gggcgggagc agcttttttg cctgcactgc tattgctgta aggaacattg atcgttttca
    11401 caatgccatc ctctgtcagt tccatgagcg gtgctactgt cttatccttc aattttacga
    11461 aatacgtagt ttcgctgttg ggcacaccta cggatttcac ttttacgcta gccagttccc
    11521 agtactcttc agggtcggcg gagacgttgg tcagtcgtag gtaacgatca gcatatttgc
    11581 tgaattctcc gggagtatag ttgactttgt tggcttttat ttcaagttct atttgggttt
    11641 tgggaagact gtaaaccact ccatagtctt ttcctcgggt aacccccgtc agtacttcgg
    11701 tttgtgcata ggcggacgtt gtcataagta gtcctgctgc tataatcaac tttttcatat
    11761 tcggttcttt ttaactggtt ttgaaaacaa agttaatgaa gttattgaaa aaagggtaag
    11821 ttcttaactt ttattcgctt acaagtcgcc atgctgtcgg cagacaggtg ataatatcgc
    11881 ttgcgatcat tccgatcatt ccttgcttct tttgagcgac atcgcccgcc agtccgtgaa
    11941 tgtaagtgcc gattttagcg gcttcctcgg tggggtaacc ttgggcaagc agtgccagga
    12001 ttactccggt cagtacgtca ccgctacctc cggttgccat tcccggattt ccggttgggt
    12061 tgaagaaaca tttaccttcg ggggtgataa tggcggagta ggctcctttt aaaataatgt
    12121 gaacatgggc ggcacgggcc agttcgcaag ccttcatcag acgttcgtaa gagtcctggc
    12181 atttgccggt cagacgttcc agttctttcg gatgcggggt gaggatggaa cccttcggca
    12241 ggtgggtaag ggcatggcgg tggttggcaa ggatattaag tgcgtcggca tccaccacaa
    12301 caggagtctg gcagtgttcc agttgttcca acaaggcagc ttccgtttcc tcgtttcgtc
    12361 ccagtcccgg accgatgccg actgcttgat agtcgtccgt gtcggtaggt acggcaaaac
    12421 aggtttcgtt gatgtcggtt tctacgattg cttcgggtat ggaggtttgc aagatgtcgt
    12481 tgttgcacat tggtgcatga acagtcagta atcctactcc cgaacggagg caggcgcggg
    12541 cagcgagaac agaggctcct gccattcctt ttgaaccggc aatcaatagt gcatggccga
    12601 agttcccctt gtgggcaaac tgtttgcgtg gcttgatgag tgaacggatt tgctctattt
    12661 ccaacatttc gtagttagtc tccatttctt caataccgtc ttcgctcaat tggatatcca
    12721 gcacttccca ttctccgaca aattccgtgt tctctgcgaa aagaaaggcg agcttcggca
    12781 gttgaagact gaaagttacg tcggcacgga taatattagc ttttacgttg aatgtgtttt
    12841 cttctcccat cagtccggaa ggaatgtcga tggctactac catggcaggg gaggaattga
    12901 tgtatttcac tacggcagcg aatccgccgc tcaacggttt gttcaggcct gaaccgaata
    12961 atccgtcgat taccagatgg tcgggcgtca gggcgggagg tacgaattgg gtactgatct
    13021 cgtggaattt tacttcttcc atcatttcta ccagttcttt attggtctgg cagtcgggtg
    13081 aaagttctcc tttcgtgttg aagagaaata cctcgatttt atatcctttt tcagccatca
    13141 tgcgggctac ggcgagagcg tctccgccat tattccccgg tccggcaaag atagtgaccg
    13201 gcgtttccgt attccatctg tctgtgatgg cttttgttaa tacggttgct gcacgttcca
    13261 tcagatcgat tgatgcaata ggttcgttct caatggtata agcgtccaat ttcttgatac
    13321 tgctgcttgg aaatattttc attgcgatgt tcttttagtt ttcggattac aaatgtacat
    13381 gattcttctg acttttcccg tttgttgtgg gaagaaaacc ataattgcaa cttttaattc
    13441 atcattagtt ctatctttgg gtcagagaaa tatctgcttt tgaactatta agtgttagaa
    13501 taactccgcc aaaaaataat tcaatgcagc accattatga acttactttt atttctcctg
    13561 aaaaagattt ctggttcttc gtcaaatttg gtggtacttc t
//
