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Overview
1.1
1.2
1.3

### Identified secondary metabolite regions using strictness 'relaxed'

gnlProkkaDKBFJBPO_1 (original name was: gnl|Prokka|DKBFJBPO_1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1 | RiPP-like | 1,160,713 | 1,171,108 |
Region 2 | lassopeptide,lanthipeptide-class-iii | 2,529,129 | 2,560,361 |
Region 3 | RiPP-like | 2,581,494 | 2,591,901 |

gnlProkkaDKBFJBPO_1 - Region 1 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,160,713 - 1,171,108 nt. (total: 10,396 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
KnownClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

gnlProkkaDKBFJBPO_1 - Region 2 - lanthipeptide-class-iii,lassopeptide
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,529,129 - 2,560,361 nt. (total: 31,233 nt) Show pHMM detection rules used
lassopeptide: (PF13471 and Asn_synthase or micJ25 or mcjC)
lanthipeptide-class-iii: (micKC and not PKS_KS)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
KnownClusterBlast
Lanthipeptides
Lasso peptides
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Lanthipeptide predictions
Shows the possible core peptides for each biosynthetic enzyme.
Includes CompaRiPPson results for any available databases, with a detailed explanation here.
Lanthipeptides - No core peptides found.
Lasso peptide predictions
Lists the possible core peptides for each biosynthetic enzyme. Each core peptide shows the leader and core peptide sequences.
Includes CompaRiPPson results for any available databases, with a detailed explanation here.

#### Lassopeptide(s) for ctg1_2296

ctg1_2296
Leader:
MKDYVPPAVEVIASFKEATN
Full core:
G V W F G N Y V D V G G A K A P F P W G S N
Putative macrolactam:
G V W F G N Y V D

#### MIBiG 3.1 matches for ctg1_2296

11.8% BGC0000535 (ADJ56352.1): Lanthipeptide: nisin A
12
G A K A P F P W G S N
22
G K G N
10
G C K T G A L M G C N
20

#### antiSMASH-DB 4.0 matches for ctg1_2296

100.0% NZ_CP062951.1 and 1 other:
NZ_CP071248.1 Lassopeptides: BLI009_RS05010_lassopeptide
Lassopeptides: BL1347_RS03935_lassopeptide
1
G V W F G N Y V D V G G A K A P F P W G S N
22
G V W F G N Y V D V G G A K A P F P W G S N
1
G V W F G N Y V D V G G A K A P F P W G S N
22
86.4% NZ_CP006714.1: Lassopeptides: B2258_RS10665_lassopeptide
1
G V W F G N Y V D V G G A K A P F P W G S N
22
G+W F G Y V D+G G A K A P F P W G S N
1
G L W F G K Y V D I G G A K A P F P W G S N
22
45.5% NZ_NGKY01000001.1: Lassopeptides: A5819_RS19010_lassopeptide
1
G V W F G N Y V D V G G A K A
15
G V W F G + D V G K A
1
G V W F G R W K D V F G G K A
15
with 8 more sequence matches
40.9% NZ_JAMDLY010000010.1 and 4 others:
NZ_JAPDMW010000034.1 Lassopeptides: OF778_RS29475_lassopeptide NZ_JMLT01000016.1 Lassopeptides: BP95_RS33025_lassopeptide NZ_LS992241.1 Lassopeptides: PBLR_RS07315_lassopeptide NZ_SADY01000011.1 Lassopeptides: C7Y44_RS26425_lassopeptide
Lassopeptides: M5X04_RS09885_lassopeptide
1
G V W F G N Y V D V G G A K A
15
G+W F G Y D V G +A
1
G I W F G R Y R D V L G G R A
15
36.4% NZ_CP053549.1 and 3 others:
NZ_JADKSM010000003.1 Lassopeptides: ITJ61_RS18070_lassopeptide NZ_PSXX01000017.1 Lassopeptides: C5E05_RS18625_lassopeptide NZ_PSXZ01000003.1 Lassopeptides: C5E07_RS02640_lassopeptide
Lassopeptides: HMI60_RS00570_lassopeptide
1
G V W F G N Y V D V G G A K A
15
G V W F G + D+ G +A
1
G V W F G R W R D I F G G R A
15
36.4% NZ_KI912489.1: Lassopeptides: allorf_513617_513742_lassopeptide
1
G V W F G N Y V D V G G A K A P F
17
G+W+G + D+ G A K F
1
G L W Y G K F R D I F G A K T Y F
17
36.4% NZ_KI912489.1: Lassopeptides: allorf_513868_514041_lassopeptide
1
G V W F G N Y V D V G G A K A
15
G V W F G + D+ G +A
1
G V W F G K W T D I F G G R A
15
34.8% NZ_AULE01000001.1: Lassopeptides: H509_RS27430_lassopeptide
1
G V W F G N Y V D V G G A K A P F P
18
G+W G Y D V G +A
1
G L W T G K Y T D V F G G R A L I K
18
34.8% NZ_JADPFA010000001.1: Lassopeptides: I4U27_RS00440_lassopeptide
1
G V W F G N Y V D V G G A K A
15
G+W G N+ D V G +A
1
G L W T G N F R D V F G G R A
15
34.8% NZ_NCVL01000001.1 and 1 other:
NZ_VMMF01000036.1 Lassopeptides: HT717_RS09510_lassopeptide
Lassopeptides: B7694_RS10650_lassopeptide
1
G V W F G N Y V D V G G A K A P F P
18
G+W F G + D+ G +A F
1
G L W F G K F T D I F G G R A V F Q
18
27.3% NZ_LMUL01000017.1: Lassopeptides: allorf_410478_410597_lassopeptide
5
G N Y V D V G G A K A P F P W G
20
G++V+ K P P G
4
G D F V E T A L T K Q P I P M G
19

#### Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine
Lanthipeptides
Lasso peptides
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists the number of lanthionine bridges, possible molecular weights, and the scores for cleavage site prediction and RODEO.
No core peptides found.
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists the number of disulfide bridges, possible molecular weights, and the scores for cleavage site prediction and RODEO.

ctg1_2296 - Class II
  Cleavage pHMM score: -3.90
  RODEO score: 18
  Monoisotopic mass: 2306.1 Da
  Molecular weight: 2307.5 Da
  Number of bridges: 0

gnlProkkaDKBFJBPO_1 - Region 3 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,581,494 - 2,591,901 nt. (total: 10,408 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
KnownClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.