## Wed Jul 10 04:02:51 2024
## emapper-2.1.12
## /d223NFS/m128030022/anaconda3/envs/eggnog/bin/emapper.py -i /d223NFS/m128030014/NGP/gene_list/prokka_results/GCA_902364815.1/GCA_902364815.1.faa --temp_dir /d223NFS/m128030022/NGPs/NGPs_new/databases/NGPs_DB/NGPs_db/GCA_902364815.1/2.eggNOGmapper --output_dir /d223NFS/m128030022/NGPs/NGPs_new/databases/NGPs_DB/NGPs_db/GCA_902364815.1/2.eggNOGmapper --output eggNOG_out --override --cpu 20 -m diamond --sensmode fast
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
HLKFIFDC_00001	411469.EUBHAL_03030	1.5e-297	811.0	COG1004@1|root,COG1004@2|Bacteria,1TQFN@1239|Firmicutes,25B1W@186801|Clostridia,25VF9@186806|Eubacteriaceae	186801|Clostridia	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
HLKFIFDC_00002	411469.EUBHAL_03031	4.48e-273	747.0	COG0562@1|root,COG0562@2|Bacteria,1TQB9@1239|Firmicutes,249BR@186801|Clostridia,25UYR@186806|Eubacteriaceae	186801|Clostridia	M	UDP-galactopyranose mutase	glf	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	GLF,NAD_binding_8
HLKFIFDC_00003	411469.EUBHAL_03032	8.65e-275	751.0	COG1216@1|root,COG1216@2|Bacteria,1UZWY@1239|Firmicutes,24A9S@186801|Clostridia,25ZP8@186806|Eubacteriaceae	186801|Clostridia	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HLKFIFDC_00004	411469.EUBHAL_03033	1.57e-197	550.0	COG1216@1|root,COG1216@2|Bacteria,1VATJ@1239|Firmicutes,24H9J@186801|Clostridia,25ZUQ@186806|Eubacteriaceae	186801|Clostridia	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HLKFIFDC_00005	411469.EUBHAL_03034	2.56e-187	533.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HLKFIFDC_00006	411469.EUBHAL_03035	3.02e-255	701.0	COG3274@1|root,COG3274@2|Bacteria	2|Bacteria	S	Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
HLKFIFDC_00007	411469.EUBHAL_03036	0.0	1194.0	29ZI5@1|root,30MI8@2|Bacteria,1V4FB@1239|Firmicutes,25FNW@186801|Clostridia,25ZQI@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00008	411469.EUBHAL_03037	2e-268	738.0	COG0463@1|root,COG0463@2|Bacteria,1VVRP@1239|Firmicutes,24GDS@186801|Clostridia,25ZK9@186806|Eubacteriaceae	186801|Clostridia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,PS_pyruv_trans
HLKFIFDC_00009	411469.EUBHAL_03038	4.22e-181	504.0	COG2197@1|root,COG2203@1|root,COG2197@2|Bacteria,COG2203@2|Bacteria,1V0Q0@1239|Firmicutes,2495W@186801|Clostridia,25Z4B@186806|Eubacteriaceae	186801|Clostridia	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
HLKFIFDC_00010	411469.EUBHAL_03040	8.42e-299	815.0	COG1649@1|root,COG1649@2|Bacteria,1TRTG@1239|Firmicutes,24B2F@186801|Clostridia,25W6I@186806|Eubacteriaceae	186801|Clostridia	S	lipoprotein YddW precursor K01189	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,GHL10,SLH
HLKFIFDC_00012	411469.EUBHAL_03041	3.19e-37	125.0	COG1918@1|root,COG1918@2|Bacteria,1VEYA@1239|Firmicutes,24QKX@186801|Clostridia,25X97@186806|Eubacteriaceae	186801|Clostridia	P	Fe2 transport system protein A	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
HLKFIFDC_00013	411469.EUBHAL_03042	2.54e-53	169.0	2E5VW@1|root,330JY@2|Bacteria,1VEZ5@1239|Firmicutes,24R14@186801|Clostridia,25X8R@186806|Eubacteriaceae	186801|Clostridia	S	H( )-transporting two-sector ATPase subunit H.a (A-type ATP synthase) K02121	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00014	411469.EUBHAL_03043	0.0	1328.0	COG2217@1|root,COG2217@2|Bacteria,1TPB8@1239|Firmicutes,247RZ@186801|Clostridia,25UW5@186806|Eubacteriaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	copA_1	-	-	ko:K12950	-	-	-	-	ko00000,ko01000	3.A.3.32	-	-	E1-E2_ATPase,Hydrolase
HLKFIFDC_00015	411469.EUBHAL_03044	5.08e-142	401.0	2BYWB@1|root,32SGE@2|Bacteria,1VAZ2@1239|Firmicutes,24J86@186801|Clostridia,25WJA@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3793
HLKFIFDC_00016	411469.EUBHAL_03045	1.5e-96	281.0	COG0716@1|root,COG0716@2|Bacteria,1V6D7@1239|Firmicutes,24J7W@186801|Clostridia,25WIN@186806|Eubacteriaceae	186801|Clostridia	C	flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1
HLKFIFDC_00017	411469.EUBHAL_03046	9.16e-301	822.0	COG0534@1|root,COG0534@2|Bacteria,1TP5P@1239|Firmicutes,247PQ@186801|Clostridia,25VG0@186806|Eubacteriaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HLKFIFDC_00019	411469.EUBHAL_00295	1.65e-93	273.0	COG1959@1|root,COG1959@2|Bacteria,1V3QB@1239|Firmicutes,24JIV@186801|Clostridia,25WZC@186806|Eubacteriaceae	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
HLKFIFDC_00020	411469.EUBHAL_00297	1.71e-283	775.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,25URE@186806|Eubacteriaceae	186801|Clostridia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
HLKFIFDC_00021	411469.EUBHAL_00298	1.9e-99	288.0	COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,24HDD@186801|Clostridia,25WT1@186806|Eubacteriaceae	186801|Clostridia	C	Fe-S iron-sulfur cluster assembly protein, NifU family	nifU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
HLKFIFDC_00022	411469.EUBHAL_00003	7.45e-150	422.0	COG0176@1|root,COG0176@2|Bacteria,1TP4Q@1239|Firmicutes,248KZ@186801|Clostridia,25V2P@186806|Eubacteriaceae	186801|Clostridia	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
HLKFIFDC_00023	411469.EUBHAL_00004	9.91e-204	563.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,25VDM@186806|Eubacteriaceae	186801|Clostridia	G	Transketolase, thiamine diphosphate binding domain protein	tktA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
HLKFIFDC_00024	411469.EUBHAL_00005	3e-222	613.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia,25USA@186806|Eubacteriaceae	186801|Clostridia	G	Transketolase, pyridine binding domain protein	tktB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
HLKFIFDC_00025	411469.EUBHAL_00795	0.0	2529.0	COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,247J1@186801|Clostridia,25V1J@186806|Eubacteriaceae	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
HLKFIFDC_00026	411469.EUBHAL_00794	0.0	2377.0	COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia,25V18@186806|Eubacteriaceae	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
HLKFIFDC_00027	411469.EUBHAL_00793	4.93e-90	264.0	COG0048@1|root,COG0048@2|Bacteria,1V1FJ@1239|Firmicutes,24FQT@186801|Clostridia,25W0M@186806|Eubacteriaceae	186801|Clostridia	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
HLKFIFDC_00028	411469.EUBHAL_00792	3.28e-105	304.0	COG0049@1|root,COG0049@2|Bacteria,1V1GG@1239|Firmicutes,24FQN@186801|Clostridia,25UQI@186806|Eubacteriaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
HLKFIFDC_00029	411469.EUBHAL_00791	0.0	1417.0	COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,25VFH@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
HLKFIFDC_00030	411469.EUBHAL_00790	1.67e-291	795.0	COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,25V5M@186806|Eubacteriaceae	186801|Clostridia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
HLKFIFDC_00031	658086.HMPREF0994_03843	8.9e-52	177.0	2E72M@1|root,331M8@2|Bacteria,1W0VG@1239|Firmicutes,24PYZ@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF2971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2971
HLKFIFDC_00032	411469.EUBHAL_00789	2.87e-107	311.0	COG1396@1|root,COG1396@2|Bacteria,1UZN9@1239|Firmicutes,24APP@186801|Clostridia,25XW6@186806|Eubacteriaceae	186801|Clostridia	K	Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HLKFIFDC_00033	411469.EUBHAL_00788	1.98e-39	130.0	2E5UB@1|root,330IM@2|Bacteria,1VI5J@1239|Firmicutes,24RAY@186801|Clostridia,25XIV@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TrmB
HLKFIFDC_00034	411469.EUBHAL_00787	2.3e-252	694.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,25VHA@186806|Eubacteriaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
HLKFIFDC_00035	411469.EUBHAL_00786	2.44e-244	672.0	COG3598@1|root,COG3598@2|Bacteria,1UIBK@1239|Firmicutes,24K1Q@186801|Clostridia,25W4E@186806|Eubacteriaceae	186801|Clostridia	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_25,Prim-Pol
HLKFIFDC_00036	411469.EUBHAL_00785	1.98e-47	153.0	2CIZU@1|root,3323B@2|Bacteria,1VF1D@1239|Firmicutes,24QPV@186801|Clostridia,25XPH@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00037	411469.EUBHAL_00784	6.14e-43	140.0	2DQEK@1|root,32UNY@2|Bacteria,1VCGS@1239|Firmicutes,24MR4@186801|Clostridia,25YZW@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF5348
HLKFIFDC_00038	411469.EUBHAL_00783	1.45e-226	636.0	COG3206@1|root,COG3206@2|Bacteria,1TR5K@1239|Firmicutes,24ARC@186801|Clostridia,25VZP@186806|Eubacteriaceae	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Mob_Pre
HLKFIFDC_00039	411469.EUBHAL_00782	1.97e-30	110.0	2C5R4@1|root,32R5C@2|Bacteria,1V57Y@1239|Firmicutes,24HAA@186801|Clostridia,25ZH5@186806|Eubacteriaceae	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
HLKFIFDC_00040	411469.EUBHAL_00781	1.07e-107	310.0	COG3727@1|root,COG3727@2|Bacteria,1V3S8@1239|Firmicutes,24MYE@186801|Clostridia,25WIB@186806|Eubacteriaceae	186801|Clostridia	L	DNA mismatch endonuclease Vsr	vsr	-	-	ko:K07458	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DUF559,Vsr
HLKFIFDC_00041	411469.EUBHAL_00780	0.0	908.0	COG3066@1|root,COG3066@2|Bacteria,1TS3J@1239|Firmicutes,249BA@186801|Clostridia	186801|Clostridia	L	DNA mismatch repair	-	-	-	-	-	-	-	-	-	-	-	-	MutH
HLKFIFDC_00042	1216932.CM240_0840	7.71e-77	252.0	28IUV@1|root,2Z8TI@2|Bacteria,1TSS1@1239|Firmicutes,24ESU@186801|Clostridia,36IE9@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00043	411469.EUBHAL_00778	0.0	877.0	COG0270@1|root,COG0270@2|Bacteria,1TS3G@1239|Firmicutes,249Q9@186801|Clostridia,25VMQ@186806|Eubacteriaceae	186801|Clostridia	H	Psort location Cytoplasmic, score	dcm	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
HLKFIFDC_00044	397287.C807_00260	0.0	1133.0	COG0846@1|root,COG0846@2|Bacteria,1UE4Y@1239|Firmicutes,24ADB@186801|Clostridia	186801|Clostridia	K	SIR2-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2
HLKFIFDC_00045	411469.EUBHAL_00774	1.18e-193	538.0	COG1284@1|root,COG1284@2|Bacteria,1TYTP@1239|Firmicutes,25CBP@186801|Clostridia,25ZSI@186806|Eubacteriaceae	186801|Clostridia	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
HLKFIFDC_00046	411469.EUBHAL_00773	0.0	863.0	28K19@1|root,2Z9R2@2|Bacteria,1TT42@1239|Firmicutes,249G4@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	zf-ribbon_3
HLKFIFDC_00047	411467.BACCAP_01435	7.17e-296	811.0	COG1775@1|root,COG1775@2|Bacteria,1TPEF@1239|Firmicutes,24A11@186801|Clostridia,26ANJ@186813|unclassified Clostridiales	186801|Clostridia	E	2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
HLKFIFDC_00048	411467.BACCAP_02456	1.48e-176	503.0	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,249CS@186801|Clostridia,267VY@186813|unclassified Clostridiales	186801|Clostridia	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
HLKFIFDC_00049	411469.EUBHAL_00771	2.37e-175	489.0	COG1924@1|root,COG1924@2|Bacteria,1TQSD@1239|Firmicutes,2481W@186801|Clostridia,25WB2@186806|Eubacteriaceae	186801|Clostridia	I	BadF/BadG/BcrA/BcrD ATPase family	hgdC	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
HLKFIFDC_00050	411469.EUBHAL_00770	4.41e-51	161.0	29XBV@1|root,30J1M@2|Bacteria,1U4VY@1239|Firmicutes,25NV8@186801|Clostridia,25Z8B@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3343
HLKFIFDC_00051	411469.EUBHAL_00769	4.31e-141	399.0	COG0425@1|root,COG0425@2|Bacteria,1V6BY@1239|Firmicutes,24JW8@186801|Clostridia,25X3M@186806|Eubacteriaceae	186801|Clostridia	O	DsrE/DsrF-like family	yedF	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE,TusA
HLKFIFDC_00052	411469.EUBHAL_00768	3.29e-236	650.0	COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,247NS@186801|Clostridia,25VSG@186806|Eubacteriaceae	186801|Clostridia	H	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
HLKFIFDC_00053	411469.EUBHAL_00767	3.9e-213	589.0	COG0583@1|root,COG0583@2|Bacteria,1TSA6@1239|Firmicutes,24BM8@186801|Clostridia,25X2I@186806|Eubacteriaceae	186801|Clostridia	K	LysR substrate binding domain	cmpR	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
HLKFIFDC_00054	411469.EUBHAL_00766	3.4e-152	428.0	COG0745@1|root,COG0745@2|Bacteria,1TR32@1239|Firmicutes,249TG@186801|Clostridia,25V3T@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K19082	ko02020,map02020	M00734,M00737	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HLKFIFDC_00055	411469.EUBHAL_00765	2.89e-214	595.0	COG0642@1|root,COG2205@2|Bacteria,1TSIC@1239|Firmicutes,248W8@186801|Clostridia,25VYA@186806|Eubacteriaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	2.7.13.3	ko:K19081	ko02020,map02020	M00734,M00737	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c
HLKFIFDC_00056	411469.EUBHAL_00764	4.59e-172	481.0	COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,247JX@186801|Clostridia,25V99@186806|Eubacteriaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HLKFIFDC_00057	411469.EUBHAL_00763	0.0	949.0	COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,2481J@186801|Clostridia,25V5H@186806|Eubacteriaceae	186801|Clostridia	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
HLKFIFDC_00058	1121115.AXVN01000064_gene4022	0.0	1184.0	COG0642@1|root,COG0784@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria,1TSDF@1239|Firmicutes,250SJ@186801|Clostridia	1239|Firmicutes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
HLKFIFDC_00059	411469.EUBHAL_02914	1.35e-284	786.0	COG4277@1|root,COG4277@2|Bacteria,1TRT2@1239|Firmicutes,247UD@186801|Clostridia,25V6I@186806|Eubacteriaceae	186801|Clostridia	L	DNA modification repair radical SAM protein	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3,Radical_SAM
HLKFIFDC_00060	411469.EUBHAL_02915	1.07e-197	547.0	2DBGV@1|root,2Z969@2|Bacteria,1UI0Y@1239|Firmicutes,25E9X@186801|Clostridia,25WGR@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4130
HLKFIFDC_00061	411902.CLOBOL_00012	1.45e-10	62.0	2DRY9@1|root,33DNC@2|Bacteria,1V1G6@1239|Firmicutes,24VHG@186801|Clostridia,2241W@1506553|Lachnoclostridium	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00062	397288.C806_04196	4.92e-118	348.0	COG2207@1|root,COG2207@2|Bacteria,1V0Z0@1239|Firmicutes,24BNN@186801|Clostridia,27K76@186928|unclassified Lachnospiraceae	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
HLKFIFDC_00063	1235790.C805_02902	8.01e-268	741.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,247VA@186801|Clostridia,25ZNV@186806|Eubacteriaceae	186801|Clostridia	G	Vacuole effluxer Atg22 like	lacS	-	-	ko:K03292,ko:K11104,ko:K16209	-	-	-	-	ko00000,ko02000	2.A.2,2.A.2.1,2.A.2.2	-	-	MFS_2
HLKFIFDC_00064	622312.ROSEINA2194_02196	0.0	1273.0	COG3345@1|root,COG3345@2|Bacteria,1TQF4@1239|Firmicutes,2489F@186801|Clostridia	186801|Clostridia	G	alpha-galactosidase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
HLKFIFDC_00065	1235802.C823_02796	1.86e-81	249.0	COG2364@1|root,COG2364@2|Bacteria,1V358@1239|Firmicutes,24GPN@186801|Clostridia,25XEB@186806|Eubacteriaceae	186801|Clostridia	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	YitT_membrane
HLKFIFDC_00066	411469.EUBHAL_02917	1.89e-227	626.0	COG0523@1|root,COG0523@2|Bacteria,1TQRE@1239|Firmicutes,24B0I@186801|Clostridia,25VJT@186806|Eubacteriaceae	186801|Clostridia	S	CobW/HypB/UreG, nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
HLKFIFDC_00067	411469.EUBHAL_02918	0.0	1041.0	COG1672@1|root,COG1672@2|Bacteria,1TQQ5@1239|Firmicutes,24918@186801|Clostridia,25VWZ@186806|Eubacteriaceae	186801|Clostridia	S	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
HLKFIFDC_00068	411469.EUBHAL_02919	0.0	924.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,2489V@186801|Clostridia,25V57@186806|Eubacteriaceae	186801|Clostridia	G	Pyruvate kinase	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
HLKFIFDC_00069	411469.EUBHAL_02920	7.17e-296	809.0	COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,248MU@186801|Clostridia,25VIR@186806|Eubacteriaceae	186801|Clostridia	E	homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
HLKFIFDC_00070	411469.EUBHAL_02922	0.0	1035.0	COG0369@1|root,COG1151@2|Bacteria,1TP8X@1239|Firmicutes,247IN@186801|Clostridia,25V33@186806|Eubacteriaceae	186801|Clostridia	C	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O	hcp	-	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	-	DUF1858,Prismane
HLKFIFDC_00071	411469.EUBHAL_02923	3.38e-72	217.0	COG1917@1|root,COG1917@2|Bacteria,1V6IB@1239|Firmicutes,24JTU@186801|Clostridia,25WYX@186806|Eubacteriaceae	186801|Clostridia	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
HLKFIFDC_00072	411469.EUBHAL_02924	5.59e-150	423.0	COG0664@1|root,COG0664@2|Bacteria,1TSP9@1239|Firmicutes,24FRD@186801|Clostridia,25WQ1@186806|Eubacteriaceae	186801|Clostridia	K	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
HLKFIFDC_00073	411469.EUBHAL_02925	7.83e-127	362.0	COG1825@1|root,COG1825@2|Bacteria,1VA38@1239|Firmicutes,24N24@186801|Clostridia,25YJ5@186806|Eubacteriaceae	186801|Clostridia	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
HLKFIFDC_00074	411469.EUBHAL_02926	2.77e-78	233.0	2CK1N@1|root,32SBC@2|Bacteria,1VCBF@1239|Firmicutes,24P0H@186801|Clostridia,25XRV@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00075	411469.EUBHAL_02927	7.88e-78	232.0	2E6A2@1|root,330XY@2|Bacteria,1VISZ@1239|Firmicutes	1239|Firmicutes	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
HLKFIFDC_00076	411469.EUBHAL_02928	0.0	1138.0	COG1297@1|root,COG1297@2|Bacteria,1TQJP@1239|Firmicutes,247JY@186801|Clostridia,25VSY@186806|Eubacteriaceae	186801|Clostridia	S	oligopeptide transporter, OPT family	-	-	-	-	-	-	-	-	-	-	-	-	OPT
HLKFIFDC_00077	411469.EUBHAL_02929	1.93e-101	294.0	2CAVT@1|root,304CC@2|Bacteria,1V4J6@1239|Firmicutes,24HQA@186801|Clostridia,25WNZ@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2798
HLKFIFDC_00078	411469.EUBHAL_02930	0.0	1326.0	COG0659@1|root,COG0659@2|Bacteria,1TPI4@1239|Firmicutes,24978@186801|Clostridia,25VMT@186806|Eubacteriaceae	186801|Clostridia	P	COG0659 Sulfate permease and related transporters (MFS superfamily)	sulP	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
HLKFIFDC_00079	411469.EUBHAL_02931	1.88e-291	796.0	COG0665@1|root,COG0665@2|Bacteria,1TR1R@1239|Firmicutes,24A67@186801|Clostridia,25WB3@186806|Eubacteriaceae	186801|Clostridia	CE	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO,Rieske
HLKFIFDC_00080	411469.EUBHAL_02933	0.0	1190.0	COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia,25UXD@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
HLKFIFDC_00081	411469.EUBHAL_01798	0.0	909.0	COG2199@1|root,COG2199@2|Bacteria,1U78Z@1239|Firmicutes,24BM3@186801|Clostridia,25ZE8@186806|Eubacteriaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_1
HLKFIFDC_00082	411469.EUBHAL_01799	3.38e-128	364.0	COG1309@1|root,COG1309@2|Bacteria,1V73E@1239|Firmicutes,25B5N@186801|Clostridia,25XHD@186806|Eubacteriaceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HLKFIFDC_00083	411469.EUBHAL_01800	0.0	1024.0	COG1757@1|root,COG1757@2|Bacteria,1TP8A@1239|Firmicutes,247V4@186801|Clostridia,25V8F@186806|Eubacteriaceae	186801|Clostridia	C	Na H antiporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
HLKFIFDC_00084	411469.EUBHAL_01801	8.34e-178	495.0	COG1349@1|root,COG1349@2|Bacteria,1UZ6T@1239|Firmicutes,24B16@186801|Clostridia,25XAU@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K02081	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
HLKFIFDC_00085	411469.EUBHAL_01802	1.35e-193	536.0	COG0561@1|root,COG0561@2|Bacteria,1V2JE@1239|Firmicutes,25B80@186801|Clostridia,25ZHT@186806|Eubacteriaceae	186801|Clostridia	S	Sucrose-6F-phosphate phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
HLKFIFDC_00086	411469.EUBHAL_01803	2.08e-284	780.0	COG1879@1|root,COG1879@2|Bacteria,1TT3I@1239|Firmicutes,247SI@186801|Clostridia,25UXG@186806|Eubacteriaceae	186801|Clostridia	G	Periplasmic binding protein domain	mglB	-	-	ko:K10540	ko02010,ko02030,map02010,map02030	M00214	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.3	-	-	Peripla_BP_4
HLKFIFDC_00087	411469.EUBHAL_01804	0.0	988.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,25VXF@186806|Eubacteriaceae	186801|Clostridia	G	ATPases associated with a variety of cellular activities	mglA	-	3.6.3.17	ko:K10441,ko:K10542	ko02010,map02010	M00212,M00214	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.3	-	-	ABC_tran
HLKFIFDC_00088	411469.EUBHAL_01805	0.0	1029.0	COG3064@1|root,COG4211@1|root,COG3064@2|Bacteria,COG4211@2|Bacteria,1UI1K@1239|Firmicutes,25EAQ@186801|Clostridia,25VS7@186806|Eubacteriaceae	186801|Clostridia	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10541	ko02010,map02010	M00214	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.3	-	-	BPD_transp_2
HLKFIFDC_00089	411469.EUBHAL_01806	0.0	1041.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TQCS@1239|Firmicutes,248SC@186801|Clostridia,25V1U@186806|Eubacteriaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
HLKFIFDC_00090	411469.EUBHAL_01807	0.0	1204.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,247XB@186801|Clostridia,25V5G@186806|Eubacteriaceae	186801|Clostridia	T	K07718 two-component system, sensor histidine kinase YesM	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,His_kinase,dCache_1
HLKFIFDC_00091	411469.EUBHAL_01813	3.64e-224	619.0	COG1879@1|root,COG1879@2|Bacteria,1UD4W@1239|Firmicutes,24AYQ@186801|Clostridia,25W6Y@186806|Eubacteriaceae	186801|Clostridia	G	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
HLKFIFDC_00092	411469.EUBHAL_01814	4.05e-242	665.0	COG1879@1|root,COG1879@2|Bacteria,1TQW5@1239|Firmicutes,249PS@186801|Clostridia,25VXK@186806|Eubacteriaceae	186801|Clostridia	G	Periplasmic binding protein domain	-	-	-	ko:K10540	ko02010,ko02030,map02010,map02030	M00214	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.3	-	-	Peripla_BP_4
HLKFIFDC_00093	411469.EUBHAL_01815	3.67e-231	637.0	COG2017@1|root,COG2017@2|Bacteria,1TQGJ@1239|Firmicutes,249DZ@186801|Clostridia,25V4H@186806|Eubacteriaceae	186801|Clostridia	G	Converts alpha-aldose to the beta-anomer	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
HLKFIFDC_00094	697329.Rumal_3660	1.82e-216	603.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia,3WJ00@541000|Ruminococcaceae	186801|Clostridia	L	transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
HLKFIFDC_00095	411469.EUBHAL_03049	0.0	919.0	COG1350@1|root,COG1350@2|Bacteria,1UI01@1239|Firmicutes,25E8Q@186801|Clostridia,25V5J@186806|Eubacteriaceae	186801|Clostridia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
HLKFIFDC_00096	411469.EUBHAL_03051	3.8e-200	556.0	COG0530@1|root,COG0530@2|Bacteria,1TRX0@1239|Firmicutes,24ABZ@186801|Clostridia,25V4F@186806|Eubacteriaceae	186801|Clostridia	P	K -dependent Na Ca exchanger family protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
HLKFIFDC_00097	411469.EUBHAL_03053	6.18e-187	524.0	COG3595@1|root,COG3595@2|Bacteria,1VA9V@1239|Firmicutes,24QYE@186801|Clostridia,25XYB@186806|Eubacteriaceae	186801|Clostridia	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
HLKFIFDC_00098	411469.EUBHAL_03054	6.08e-129	368.0	COG4709@1|root,COG4709@2|Bacteria,1VBG6@1239|Firmicutes,24N6S@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1700
HLKFIFDC_00099	411469.EUBHAL_03055	6.11e-74	221.0	COG1695@1|root,COG1695@2|Bacteria,1VA8W@1239|Firmicutes,24NE2@186801|Clostridia	186801|Clostridia	K	transcriptional regulator, PadR family	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
HLKFIFDC_00100	411469.EUBHAL_03056	4.56e-78	233.0	COG1725@1|root,COG1725@2|Bacteria,1VFD0@1239|Firmicutes,24MTU@186801|Clostridia,25X79@186806|Eubacteriaceae	186801|Clostridia	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
HLKFIFDC_00101	411469.EUBHAL_03057	5.53e-211	583.0	COG1131@1|root,COG1131@2|Bacteria,1TPQW@1239|Firmicutes,248F7@186801|Clostridia,25VUY@186806|Eubacteriaceae	186801|Clostridia	V	ABC-type multidrug transport system, ATPase component	ytrB	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HLKFIFDC_00102	411469.EUBHAL_03058	0.0	1201.0	COG1277@1|root,COG1277@2|Bacteria,1TRJ8@1239|Firmicutes,24EMN@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
HLKFIFDC_00104	622312.ROSEINA2194_00364	0.00031	45.4	COG4767@1|root,COG4767@2|Bacteria,1VKIA@1239|Firmicutes,24RR9@186801|Clostridia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
HLKFIFDC_00105	411469.EUBHAL_03060	4.46e-296	812.0	COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,2483Q@186801|Clostridia,25UX9@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	pbuG	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
HLKFIFDC_00106	411469.EUBHAL_03061	1.96e-151	426.0	COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,248FV@186801|Clostridia,25V9I@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
HLKFIFDC_00107	411469.EUBHAL_00104	1.63e-37	125.0	COG1476@1|root,COG1476@2|Bacteria,1VERT@1239|Firmicutes,24QJJ@186801|Clostridia,25X7F@186806|Eubacteriaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
HLKFIFDC_00109	411469.EUBHAL_01696	4.68e-182	506.0	COG3022@1|root,COG3022@2|Bacteria,1TR33@1239|Firmicutes,248N1@186801|Clostridia,25VSE@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the UPF0246 family	-	-	-	ko:K09861	-	-	-	-	ko00000	-	-	-	H2O2_YaaD
HLKFIFDC_00110	411469.EUBHAL_01697	7.9e-288	786.0	COG4286@1|root,COG4286@2|Bacteria,1V2PW@1239|Firmicutes,248SR@186801|Clostridia,25YHB@186806|Eubacteriaceae	186801|Clostridia	S	Uncharacterised protein family (UPF0160)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0160
HLKFIFDC_00111	411469.EUBHAL_01698	1.29e-234	646.0	COG0310@1|root,COG0310@2|Bacteria,1TPEN@1239|Firmicutes,248S9@186801|Clostridia,25V9E@186806|Eubacteriaceae	186801|Clostridia	P	cobalamin biosynthesis protein	cbiM2	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM,PDGLE
HLKFIFDC_00112	411469.EUBHAL_01699	5.66e-192	533.0	COG0619@1|root,COG0619@2|Bacteria,1V7YC@1239|Firmicutes,25D5P@186801|Clostridia	186801|Clostridia	P	cobalt transport protein	-	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
HLKFIFDC_00113	411469.EUBHAL_01700	1.02e-158	444.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia	186801|Clostridia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	-	-	-	ko:K02006,ko:K16787	ko02010,map02010	M00245,M00246,M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.18,3.A.1.22,3.A.1.23,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
HLKFIFDC_00114	411469.EUBHAL_01701	2.23e-245	677.0	2DBN5@1|root,2ZA1Y@2|Bacteria,1UZYG@1239|Firmicutes,249F5@186801|Clostridia,25Z5P@186806|Eubacteriaceae	186801|Clostridia	S	Domain of unknown function (DUF4179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4179
HLKFIFDC_00115	411469.EUBHAL_01702	5.78e-139	392.0	COG1595@1|root,COG1595@2|Bacteria,1V55A@1239|Firmicutes,24GME@186801|Clostridia,25X6S@186806|Eubacteriaceae	186801|Clostridia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HLKFIFDC_00116	411469.EUBHAL_01703	0.0	1199.0	COG0122@1|root,COG0561@1|root,COG0122@2|Bacteria,COG0561@2|Bacteria,1TQAF@1239|Firmicutes,2495X@186801|Clostridia,25WET@186806|Eubacteriaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	alkA	-	4.2.99.18	ko:K03660	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD,OGG_N
HLKFIFDC_00117	411469.EUBHAL_01704	4.11e-222	611.0	COG1307@1|root,COG1307@2|Bacteria,1TQDI@1239|Firmicutes,25B4M@186801|Clostridia,25VYJ@186806|Eubacteriaceae	186801|Clostridia	S	EDD domain protein, DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
HLKFIFDC_00118	411469.EUBHAL_01705	0.0	1060.0	COG2340@1|root,COG2340@2|Bacteria,1VQ1W@1239|Firmicutes,24W63@186801|Clostridia	186801|Clostridia	S	Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
HLKFIFDC_00119	411469.EUBHAL_01706	0.0	1868.0	2DB7E@1|root,2Z7KT@2|Bacteria,1V0PC@1239|Firmicutes,24D3B@186801|Clostridia,25VZ1@186806|Eubacteriaceae	186801|Clostridia	S	Penicillin-binding protein Tp47 domain a	-	-	-	-	-	-	-	-	-	-	-	-	DUF1533,PBP-Tp47_a,PBP-Tp47_c
HLKFIFDC_00120	411469.EUBHAL_01707	3.15e-257	706.0	COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,248KJ@186801|Clostridia,25WF5@186806|Eubacteriaceae	186801|Clostridia	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
HLKFIFDC_00121	411469.EUBHAL_01708	2.36e-295	821.0	COG3976@1|root,COG3976@2|Bacteria,1TR5A@1239|Firmicutes,25E6J@186801|Clostridia,25WV2@186806|Eubacteriaceae	186801|Clostridia	S	FMN-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind,Fer4_5
HLKFIFDC_00122	411469.EUBHAL_01709	6.97e-99	288.0	COG3976@1|root,COG3976@2|Bacteria,1VENM@1239|Firmicutes,24RRX@186801|Clostridia,25YW3@186806|Eubacteriaceae	186801|Clostridia	S	FMN-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
HLKFIFDC_00123	411469.EUBHAL_01710	6.23e-182	508.0	COG0348@1|root,COG0348@2|Bacteria,1TPHF@1239|Firmicutes,247KH@186801|Clostridia,25WT0@186806|Eubacteriaceae	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
HLKFIFDC_00124	411469.EUBHAL_01711	7.89e-217	600.0	COG0714@1|root,COG0714@2|Bacteria,1TPKR@1239|Firmicutes,248IM@186801|Clostridia,25UR5@186806|Eubacteriaceae	186801|Clostridia	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
HLKFIFDC_00125	411469.EUBHAL_01712	1.33e-276	757.0	COG1721@1|root,COG1721@2|Bacteria,1UZHY@1239|Firmicutes,24FIT@186801|Clostridia,25XDN@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
HLKFIFDC_00126	411469.EUBHAL_01713	0.0	1396.0	COG1305@1|root,COG1305@2|Bacteria,1TP8K@1239|Firmicutes,24CZV@186801|Clostridia,25X9J@186806|Eubacteriaceae	186801|Clostridia	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
HLKFIFDC_00127	411469.EUBHAL_01714	3.64e-219	603.0	COG1092@1|root,COG1092@2|Bacteria,1TPUD@1239|Firmicutes,2480X@186801|Clostridia,25VPS@186806|Eubacteriaceae	186801|Clostridia	H	S-adenosylmethionine-dependent methyltransferase	rlmL_1	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
HLKFIFDC_00128	411469.EUBHAL_01715	2.55e-92	272.0	COG4769@1|root,COG4769@2|Bacteria,1V1M0@1239|Firmicutes,24MZC@186801|Clostridia,25WXG@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	Hpre_diP_synt_I
HLKFIFDC_00130	411469.EUBHAL_01717	2.65e-216	597.0	COG0583@1|root,COG0583@2|Bacteria,1TRJK@1239|Firmicutes,24AY4@186801|Clostridia,25VY5@186806|Eubacteriaceae	186801|Clostridia	K	Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
HLKFIFDC_00131	411469.EUBHAL_01718	9.72e-156	437.0	COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,24A6Q@186801|Clostridia,25VMP@186806|Eubacteriaceae	186801|Clostridia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
HLKFIFDC_00132	411469.EUBHAL_01719	5.78e-30	107.0	COG0636@1|root,COG0636@2|Bacteria,1V8SD@1239|Firmicutes,24QMQ@186801|Clostridia,25X8S@186806|Eubacteriaceae	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iHN637.CLJU_RS01165	ATP-synt_C
HLKFIFDC_00133	411469.EUBHAL_01720	1.7e-63	198.0	COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,24RWR@186801|Clostridia,25X82@186806|Eubacteriaceae	186801|Clostridia	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
HLKFIFDC_00134	411469.EUBHAL_01721	4.18e-118	338.0	COG0712@1|root,COG0712@2|Bacteria,1UI0C@1239|Firmicutes,24G5C@186801|Clostridia,25XIU@186806|Eubacteriaceae	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
HLKFIFDC_00135	411469.EUBHAL_01722	0.0	959.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia,25V5E@186806|Eubacteriaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N,OSCP
HLKFIFDC_00136	411469.EUBHAL_01723	5.26e-203	563.0	COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,2486Q@186801|Clostridia,25VH1@186806|Eubacteriaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
HLKFIFDC_00137	411469.EUBHAL_01724	0.0	902.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia,25UUG@186806|Eubacteriaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
HLKFIFDC_00138	411469.EUBHAL_01725	8.7e-91	266.0	COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,24ND7@186801|Clostridia,25WUT@186806|Eubacteriaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
HLKFIFDC_00140	411469.EUBHAL_01728	3.53e-217	602.0	COG5464@1|root,COG5464@2|Bacteria,1UA0N@1239|Firmicutes,247X9@186801|Clostridia,25WKX@186806|Eubacteriaceae	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
HLKFIFDC_00141	411469.EUBHAL_01729	7.21e-146	410.0	COG0622@1|root,COG0622@2|Bacteria,1V1X1@1239|Firmicutes,24GA4@186801|Clostridia,25WG0@186806|Eubacteriaceae	186801|Clostridia	S	Cytoplasmic, score	yfcE	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
HLKFIFDC_00143	411469.EUBHAL_01731	1.9e-108	312.0	2CV0R@1|root,32SWK@2|Bacteria,1VDAN@1239|Firmicutes,24K0G@186801|Clostridia	186801|Clostridia	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
HLKFIFDC_00144	411469.EUBHAL_01732	2.1e-264	730.0	COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,248KJ@186801|Clostridia,25WF5@186806|Eubacteriaceae	186801|Clostridia	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
HLKFIFDC_00145	411469.EUBHAL_01733	2.75e-66	201.0	COG0051@1|root,COG0051@2|Bacteria,1V6C9@1239|Firmicutes,24JDC@186801|Clostridia,25WIW@186806|Eubacteriaceae	186801|Clostridia	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
HLKFIFDC_00146	411469.EUBHAL_01734	8.75e-145	408.0	COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,247NH@186801|Clostridia,25VIA@186806|Eubacteriaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
HLKFIFDC_00147	411469.EUBHAL_01735	1.26e-127	364.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,25VEH@186806|Eubacteriaceae	186801|Clostridia	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
HLKFIFDC_00148	411469.EUBHAL_01736	8.14e-63	192.0	COG0089@1|root,COG0089@2|Bacteria,1VA4W@1239|Firmicutes,24MN8@186801|Clostridia,25WX7@186806|Eubacteriaceae	186801|Clostridia	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
HLKFIFDC_00149	411469.EUBHAL_01737	6.81e-192	533.0	COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,247XY@186801|Clostridia,25UQE@186806|Eubacteriaceae	186801|Clostridia	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
HLKFIFDC_00150	411469.EUBHAL_01738	6.15e-62	189.0	COG0185@1|root,COG0185@2|Bacteria,1V6CX@1239|Firmicutes,24JN3@186801|Clostridia,25WMJ@186806|Eubacteriaceae	186801|Clostridia	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
HLKFIFDC_00151	411469.EUBHAL_01739	7.74e-86	253.0	COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,24JF4@186801|Clostridia,25WWP@186806|Eubacteriaceae	186801|Clostridia	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
HLKFIFDC_00152	411469.EUBHAL_01740	2.14e-155	436.0	COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,24833@186801|Clostridia,25VHR@186806|Eubacteriaceae	186801|Clostridia	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
HLKFIFDC_00153	411469.EUBHAL_01741	1.22e-102	296.0	COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,24FQX@186801|Clostridia,25W3Z@186806|Eubacteriaceae	186801|Clostridia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
HLKFIFDC_00154	411469.EUBHAL_01742	1.3e-36	124.0	COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,24QV1@186801|Clostridia,25XGM@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
HLKFIFDC_00155	411469.EUBHAL_01743	2.67e-52	164.0	COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,24MSW@186801|Clostridia,25WUN@186806|Eubacteriaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
HLKFIFDC_00156	411469.EUBHAL_01744	4.41e-80	238.0	COG0093@1|root,COG0093@2|Bacteria,1V3N0@1239|Firmicutes,24H98@186801|Clostridia,25WCX@186806|Eubacteriaceae	186801|Clostridia	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
HLKFIFDC_00157	411469.EUBHAL_01745	3.67e-65	198.0	COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,24MY0@186801|Clostridia,25WQ0@186806|Eubacteriaceae	186801|Clostridia	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
HLKFIFDC_00158	411469.EUBHAL_01746	1.39e-124	355.0	COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,247X0@186801|Clostridia,25V67@186806|Eubacteriaceae	186801|Clostridia	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
HLKFIFDC_00159	411469.EUBHAL_01747	2.83e-28	102.0	COG0199@1|root,COG0199@2|Bacteria,1VEF6@1239|Firmicutes,24QR1@186801|Clostridia,25X7N@186806|Eubacteriaceae	186801|Clostridia	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
HLKFIFDC_00160	411469.EUBHAL_01748	3.49e-89	261.0	COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,24HCP@186801|Clostridia,25W8Y@186806|Eubacteriaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
HLKFIFDC_00161	411469.EUBHAL_01749	1.54e-120	345.0	COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,2496R@186801|Clostridia,25UZ9@186806|Eubacteriaceae	186801|Clostridia	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
HLKFIFDC_00162	411469.EUBHAL_01750	4.07e-76	228.0	COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,24JCS@186801|Clostridia,25WB4@186806|Eubacteriaceae	186801|Clostridia	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
HLKFIFDC_00163	411469.EUBHAL_01751	3.15e-109	315.0	COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,25WCN@186806|Eubacteriaceae	186801|Clostridia	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
HLKFIFDC_00164	411469.EUBHAL_01752	1.24e-35	120.0	COG1841@1|root,COG1841@2|Bacteria,1VEG4@1239|Firmicutes,24QKC@186801|Clostridia,25X9Q@186806|Eubacteriaceae	186801|Clostridia	J	COG1841 Ribosomal protein L30 L7E	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
HLKFIFDC_00165	411469.EUBHAL_01753	1.12e-94	276.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia,25WJV@186806|Eubacteriaceae	186801|Clostridia	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
HLKFIFDC_00166	411469.EUBHAL_01754	1.87e-306	836.0	COG0201@1|root,COG0201@2|Bacteria,1TPHB@1239|Firmicutes,248T9@186801|Clostridia,25USD@186806|Eubacteriaceae	186801|Clostridia	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
HLKFIFDC_00167	411469.EUBHAL_01755	0.0	965.0	COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia,25V7H@186806|Eubacteriaceae	186801|Clostridia	P	FAD dependent oxidoreductase	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD
HLKFIFDC_00168	411469.EUBHAL_01756	1.86e-304	830.0	COG0446@1|root,COG0446@2|Bacteria,1TQH5@1239|Firmicutes,247YR@186801|Clostridia,25VR2@186806|Eubacteriaceae	186801|Clostridia	C	Pyridine nucleotide-disulfide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_3
HLKFIFDC_00169	411469.EUBHAL_01757	3.93e-78	233.0	COG3862@1|root,COG3862@2|Bacteria,1VA4U@1239|Firmicutes,24MN9@186801|Clostridia,25WVW@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF1667)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1667
HLKFIFDC_00171	411469.EUBHAL_00631	2.94e-154	432.0	COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,247YN@186801|Clostridia,25UWE@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS20110	ADK,ADK_lid
HLKFIFDC_00172	411469.EUBHAL_00632	9.27e-60	184.0	COG1669@1|root,COG1669@2|Bacteria,1VEWI@1239|Firmicutes,25DNH@186801|Clostridia,25XNX@186806|Eubacteriaceae	186801|Clostridia	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
HLKFIFDC_00173	411469.EUBHAL_00633	8.91e-87	256.0	COG1669@1|root,COG1669@2|Bacteria,1V7CK@1239|Firmicutes,25DJI@186801|Clostridia,25X02@186806|Eubacteriaceae	186801|Clostridia	S	Nucleotidyltransferase substrate binding protein like	-	-	-	-	-	-	-	-	-	-	-	-	NTase_sub_bind
HLKFIFDC_00174	411469.EUBHAL_00634	4.17e-191	530.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia,25V68@186806|Eubacteriaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
HLKFIFDC_00175	411469.EUBHAL_00635	6.08e-63	192.0	2A0AP@1|root,30NE4@2|Bacteria,1UHB1@1239|Firmicutes,25Q15@186801|Clostridia,25Y02@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00176	411469.EUBHAL_00636	3.42e-45	145.0	COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,24MQE@186801|Clostridia,25WYK@186806|Eubacteriaceae	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
HLKFIFDC_00177	411469.EUBHAL_00637	7.32e-79	234.0	COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia,25WK3@186806|Eubacteriaceae	186801|Clostridia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
HLKFIFDC_00178	411469.EUBHAL_00638	2.85e-69	211.0	COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,24HIK@186801|Clostridia,25W9E@186806|Eubacteriaceae	186801|Clostridia	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
HLKFIFDC_00179	411469.EUBHAL_00639	1.72e-136	386.0	COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia,25VYW@186806|Eubacteriaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
HLKFIFDC_00180	411469.EUBHAL_00640	8.86e-218	602.0	COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,248DS@186801|Clostridia,25UT6@186806|Eubacteriaceae	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
HLKFIFDC_00181	411469.EUBHAL_00641	5.2e-115	330.0	COG0203@1|root,COG0203@2|Bacteria,1V6JQ@1239|Firmicutes,24J9T@186801|Clostridia,25W4B@186806|Eubacteriaceae	186801|Clostridia	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
HLKFIFDC_00182	411469.EUBHAL_00642	0.0	1326.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia,25URB@186806|Eubacteriaceae	186801|Clostridia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfA2	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
HLKFIFDC_00183	411469.EUBHAL_00643	2.86e-178	498.0	COG0619@1|root,COG0619@2|Bacteria,1TQ0E@1239|Firmicutes,248AB@186801|Clostridia,25UR8@186806|Eubacteriaceae	186801|Clostridia	P	Cobalt transport protein	ecfT	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
HLKFIFDC_00184	411469.EUBHAL_00644	1.01e-177	495.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,248W2@186801|Clostridia,25US1@186806|Eubacteriaceae	186801|Clostridia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
HLKFIFDC_00185	411469.EUBHAL_00645	7.13e-100	289.0	COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,24HD9@186801|Clostridia,25WEH@186806|Eubacteriaceae	186801|Clostridia	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
HLKFIFDC_00186	411469.EUBHAL_00646	3.13e-86	254.0	COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia,25W96@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
HLKFIFDC_00187	411469.EUBHAL_00647	0.0	1019.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia,25V8V@186806|Eubacteriaceae	186801|Clostridia	S	of ABC transporters with duplicated ATPase	yfmM	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
HLKFIFDC_00188	411469.EUBHAL_00648	8.65e-202	560.0	COG0679@1|root,COG0679@2|Bacteria,1V28G@1239|Firmicutes,24H5F@186801|Clostridia	186801|Clostridia	S	auxin efflux carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
HLKFIFDC_00189	411469.EUBHAL_00649	1.81e-157	442.0	COG2186@1|root,COG2186@2|Bacteria,1V2TU@1239|Firmicutes,24GA8@186801|Clostridia,25VX8@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
HLKFIFDC_00190	411469.EUBHAL_00650	3.11e-217	597.0	COG0726@1|root,COG0726@2|Bacteria,1VA2Q@1239|Firmicutes,24B9K@186801|Clostridia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
HLKFIFDC_00191	411469.EUBHAL_00651	5.57e-213	586.0	COG0726@1|root,COG0726@2|Bacteria,1VA2Q@1239|Firmicutes,24FN0@186801|Clostridia	186801|Clostridia	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
HLKFIFDC_00192	411469.EUBHAL_00652	0.0	937.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,25VM4@186806|Eubacteriaceae	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	Na_Ala_symp
HLKFIFDC_00193	768710.DesyoDRAFT_2772	6.34e-48	156.0	COG3576@1|root,COG3576@2|Bacteria,1VI61@1239|Firmicutes,24T5M@186801|Clostridia	186801|Clostridia	S	5'-phosphate oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
HLKFIFDC_00194	428126.CLOSPI_00516	8.24e-164	476.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,3VP4Q@526524|Erysipelotrichia	526524|Erysipelotrichia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HLKFIFDC_00195	1504823.CCMM01000013_gene2391	1.16e-23	90.9	COG1733@1|root,COG1733@2|Bacteria	2|Bacteria	K	regulation of RNA biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	HxlR,Replic_Relax
HLKFIFDC_00196	411469.EUBHAL_00045	4.95e-250	686.0	COG3093@1|root,COG3093@2|Bacteria,1V0AU@1239|Firmicutes,24BH5@186801|Clostridia,25WYN@186806|Eubacteriaceae	186801|Clostridia	K	antidote protein	higA	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_3,Peptidase_M78
HLKFIFDC_00197	411469.EUBHAL_00046	6.9e-129	365.0	COG1247@1|root,COG1247@2|Bacteria,1V6X5@1239|Firmicutes,24IB5@186801|Clostridia,25W9H@186806|Eubacteriaceae	186801|Clostridia	M	Acetyltransferase (GNAT) family	pat	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
HLKFIFDC_00198	411469.EUBHAL_00047	2.73e-293	801.0	COG0205@1|root,COG0205@2|Bacteria,1TRJQ@1239|Firmicutes,247IV@186801|Clostridia,25VUF@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
HLKFIFDC_00199	411469.EUBHAL_00048	3.98e-184	512.0	COG1348@1|root,COG1348@2|Bacteria,1TPXR@1239|Firmicutes,247KJ@186801|Clostridia,25W01@186806|Eubacteriaceae	186801|Clostridia	P	Belongs to the NifH BchL ChlL family	-	-	1.18.6.1	ko:K02588	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_NifH
HLKFIFDC_00200	411469.EUBHAL_00049	0.0	897.0	COG2710@1|root,COG2710@2|Bacteria,1U1IK@1239|Firmicutes,25DHB@186801|Clostridia,25VXR@186806|Eubacteriaceae	186801|Clostridia	C	Nitrogenase component 1 type Oxidoreductase	-	-	-	ko:K02587	-	-	-	-	ko00000	-	-	-	Oxidored_nitro
HLKFIFDC_00201	411469.EUBHAL_00050	3.99e-251	690.0	COG2710@1|root,COG2710@2|Bacteria,1TSY8@1239|Firmicutes,24BHA@186801|Clostridia,25VXY@186806|Eubacteriaceae	186801|Clostridia	C	Nitrogenase component 1 type Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_nitro
HLKFIFDC_00202	411469.EUBHAL_00051	0.0	1526.0	COG0068@1|root,COG0068@2|Bacteria,1TQM7@1239|Firmicutes,2494A@186801|Clostridia,25VWK@186806|Eubacteriaceae	186801|Clostridia	O	HypF finger	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
HLKFIFDC_00203	411469.EUBHAL_00052	4.29e-40	132.0	COG0298@1|root,COG0298@2|Bacteria,1VEMQ@1239|Firmicutes,24RN2@186801|Clostridia	186801|Clostridia	O	Hydrogenase assembly chaperone hypC hupF	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	iHN637.CLJU_RS11355	HupF_HypC
HLKFIFDC_00204	411469.EUBHAL_00053	5.7e-262	716.0	COG0409@1|root,COG0409@2|Bacteria,1TPM7@1239|Firmicutes,248EX@186801|Clostridia,25UTZ@186806|Eubacteriaceae	186801|Clostridia	O	hydrogenase expression formation protein HypD	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
HLKFIFDC_00205	411469.EUBHAL_00054	4.54e-241	662.0	COG0309@1|root,COG0309@2|Bacteria,1TQP4@1239|Firmicutes,24963@186801|Clostridia,25VSI@186806|Eubacteriaceae	186801|Clostridia	O	AIR synthase related protein, N-terminal domain	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
HLKFIFDC_00206	411469.EUBHAL_00055	5.27e-49	156.0	COG0864@1|root,COG0864@2|Bacteria,1VF9M@1239|Firmicutes,24QVJ@186801|Clostridia,25XEG@186806|Eubacteriaceae	186801|Clostridia	K	iron-only hydrogenase system regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00207	411469.EUBHAL_00056	1.32e-169	474.0	COG1348@1|root,COG1348@2|Bacteria,1TPXR@1239|Firmicutes,247KJ@186801|Clostridia,25VIN@186806|Eubacteriaceae	186801|Clostridia	P	Belongs to the NifH BchL ChlL family	nifH1	-	1.18.6.1	ko:K02588	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_NifH
HLKFIFDC_00208	411469.EUBHAL_00057	0.0	928.0	COG2710@1|root,COG2710@2|Bacteria,1TS4H@1239|Firmicutes,24BC1@186801|Clostridia,25VYK@186806|Eubacteriaceae	186801|Clostridia	C	Nitrogenase component 1 type Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_nitro
HLKFIFDC_00209	411469.EUBHAL_00058	2.12e-291	797.0	COG2710@1|root,COG2710@2|Bacteria,1TRSJ@1239|Firmicutes,24AEW@186801|Clostridia,25VUX@186806|Eubacteriaceae	186801|Clostridia	C	Nitrogenase component 1 type Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_nitro
HLKFIFDC_00210	411469.EUBHAL_00059	9.96e-141	397.0	COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249VD@186801|Clostridia,25WCD@186806|Eubacteriaceae	186801|Clostridia	F	Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
HLKFIFDC_00211	411469.EUBHAL_00060	0.0	1187.0	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,247SG@186801|Clostridia,25V8P@186806|Eubacteriaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	pepQ	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
HLKFIFDC_00212	411469.EUBHAL_00061	1.49e-165	463.0	COG1028@1|root,COG1028@2|Bacteria,1TZY6@1239|Firmicutes,248QZ@186801|Clostridia,25WC1@186806|Eubacteriaceae	186801|Clostridia	IQ	Oxidoreductase, short chain dehydrogenase reductase family protein	fabG2	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
HLKFIFDC_00213	411469.EUBHAL_00063	5.16e-310	850.0	2E2WU@1|root,32XY0@2|Bacteria,1VDG4@1239|Firmicutes,24NB8@186801|Clostridia,25ZB6@186806|Eubacteriaceae	186801|Clostridia	S	LytR cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
HLKFIFDC_00214	411469.EUBHAL_00064	5.87e-193	536.0	COG1922@1|root,COG1922@2|Bacteria,1V3QV@1239|Firmicutes,24AQ3@186801|Clostridia,25XW7@186806|Eubacteriaceae	186801|Clostridia	M	Glycosyl transferase WecB/TagA/CpsF family	tagA	-	2.4.1.187	ko:K05946	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT26	-	Glyco_tran_WecB
HLKFIFDC_00215	411469.EUBHAL_00066	6.1e-171	477.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,25V1F@186806|Eubacteriaceae	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
HLKFIFDC_00216	411469.EUBHAL_02341	1.94e-254	699.0	COG2508@1|root,COG2508@2|Bacteria,1TTA0@1239|Firmicutes,248HN@186801|Clostridia,25V2S@186806|Eubacteriaceae	186801|Clostridia	QT	Psort location Cytoplasmic, score	cdaR_3	-	-	ko:K02647	-	-	-	-	ko00000,ko03000	-	-	-	HTH_30
HLKFIFDC_00217	411469.EUBHAL_02343	1.81e-291	797.0	COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,248HZ@186801|Clostridia,25VR7@186806|Eubacteriaceae	186801|Clostridia	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
HLKFIFDC_00218	411469.EUBHAL_02344	7.24e-112	321.0	2C2B5@1|root,32RA4@2|Bacteria,1V6P1@1239|Firmicutes,24N51@186801|Clostridia,25X7Z@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00219	411469.EUBHAL_02345	8.04e-315	856.0	COG1362@1|root,COG1362@2|Bacteria,1TQ3Z@1239|Firmicutes,248UP@186801|Clostridia,25VMC@186806|Eubacteriaceae	186801|Clostridia	E	M18 family aminopeptidase	apeB	-	3.4.11.21	ko:K01267	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	Peptidase_M18
HLKFIFDC_00220	411469.EUBHAL_02346	0.0	954.0	COG0699@1|root,COG0699@2|Bacteria,1TPPG@1239|Firmicutes,24829@186801|Clostridia,25VU1@186806|Eubacteriaceae	186801|Clostridia	S	ATPase. Has a role at an early stage in the morphogenesis of the spore coat	spoIVA	GO:0000003,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0008144,GO:0008150,GO:0009653,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019954,GO:0030154,GO:0030312,GO:0030435,GO:0030436,GO:0030554,GO:0031160,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0034301,GO:0035639,GO:0036094,GO:0042601,GO:0042763,GO:0043167,GO:0043168,GO:0043934,GO:0043936,GO:0044464,GO:0048646,GO:0048856,GO:0048869,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K06398	-	-	-	-	ko00000	-	-	-	Spore_IV_A
HLKFIFDC_00221	411469.EUBHAL_02347	3.69e-188	523.0	COG2357@1|root,COG2357@2|Bacteria,1TQ2F@1239|Firmicutes,249FE@186801|Clostridia,25VVW@186806|Eubacteriaceae	186801|Clostridia	S	RelA SpoT domain protein	yjbM	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
HLKFIFDC_00222	411469.EUBHAL_02348	0.0	991.0	COG0144@1|root,COG0144@2|Bacteria,1TPGQ@1239|Firmicutes,247N0@186801|Clostridia,25V2B@186806|Eubacteriaceae	186801|Clostridia	J	NOL1 NOP2 sun family	rsmF	-	-	-	-	-	-	-	-	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA,RsmF_methylt_CI
HLKFIFDC_00223	411469.EUBHAL_02350	2.37e-163	458.0	COG1187@1|root,COG1187@2|Bacteria,1TQZ2@1239|Firmicutes,248HC@186801|Clostridia,25W6P@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rsuA	-	5.4.99.19	ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
HLKFIFDC_00224	411469.EUBHAL_02352	0.0	1347.0	COG1032@1|root,COG1032@2|Bacteria,1TQ8X@1239|Firmicutes,248IW@186801|Clostridia,25VRA@186806|Eubacteriaceae	186801|Clostridia	C	UPF0313 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
HLKFIFDC_00225	411469.EUBHAL_02353	5e-175	488.0	COG0300@1|root,COG0300@2|Bacteria,1V3UX@1239|Firmicutes,25B0Y@186801|Clostridia,25WEG@186806|Eubacteriaceae	186801|Clostridia	S	Enoyl-(Acyl carrier protein) reductase	sdh	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
HLKFIFDC_00226	411469.EUBHAL_02354	9.86e-269	739.0	COG0564@1|root,COG0564@2|Bacteria,1TR1M@1239|Firmicutes,248W3@186801|Clostridia,25VUW@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the pseudouridine synthase RluA family	rluC	-	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
HLKFIFDC_00227	411469.EUBHAL_02355	1.1e-131	373.0	COG3331@1|root,COG3331@2|Bacteria,1V3S4@1239|Firmicutes,24G7S@186801|Clostridia,25W2C@186806|Eubacteriaceae	186801|Clostridia	L	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation	recU	-	-	ko:K03700	-	-	-	-	ko00000,ko03400	-	-	-	RecU
HLKFIFDC_00228	411469.EUBHAL_02356	5.91e-197	547.0	COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,24824@186801|Clostridia,25VXT@186806|Eubacteriaceae	186801|Clostridia	S	TIGR00255 family	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
HLKFIFDC_00229	411469.EUBHAL_02357	5.85e-56	174.0	COG2052@1|root,COG2052@2|Bacteria,1VA40@1239|Firmicutes,24MXV@186801|Clostridia,25X81@186806|Eubacteriaceae	186801|Clostridia	S	Domain of unknown function (DUF370)	NPD7_560	-	-	ko:K09777	-	-	-	-	ko00000	-	-	-	DUF370
HLKFIFDC_00230	411469.EUBHAL_02358	3.4e-145	410.0	COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,24HEX@186801|Clostridia,25WGB@186806|Eubacteriaceae	186801|Clostridia	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
HLKFIFDC_00231	411469.EUBHAL_02359	1.98e-60	186.0	COG1758@1|root,COG1758@2|Bacteria,1VF65@1239|Firmicutes,25Q91@186801|Clostridia,25X3H@186806|Eubacteriaceae	186801|Clostridia	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	-	-	-	-	-	-	-	-	-	-	RNA_pol_Rpb6
HLKFIFDC_00232	411469.EUBHAL_02360	7.94e-172	481.0	COG5652@1|root,COG5652@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	VanZ
HLKFIFDC_00233	411469.EUBHAL_02361	0.0	973.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia,25VGR@186806|Eubacteriaceae	186801|Clostridia	M	to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HLKFIFDC_00234	411469.EUBHAL_02362	0.0	1466.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,248EI@186801|Clostridia,25V1S@186806|Eubacteriaceae	186801|Clostridia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
HLKFIFDC_00235	411469.EUBHAL_02363	1.75e-110	317.0	COG0242@1|root,COG0242@2|Bacteria,1V70B@1239|Firmicutes,24JET@186801|Clostridia,25WDW@186806|Eubacteriaceae	186801|Clostridia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
HLKFIFDC_00236	411469.EUBHAL_02364	1.55e-223	616.0	COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,248ED@186801|Clostridia,25UWW@186806|Eubacteriaceae	186801|Clostridia	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
HLKFIFDC_00237	411469.EUBHAL_02365	0.0	885.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1TP3N@1239|Firmicutes,248CS@186801|Clostridia,25VS9@186806|Eubacteriaceae	186801|Clostridia	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
HLKFIFDC_00238	411469.EUBHAL_02366	5.02e-255	699.0	COG0820@1|root,COG0820@2|Bacteria,1TPVF@1239|Firmicutes,248BC@186801|Clostridia,25UW3@186806|Eubacteriaceae	186801|Clostridia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
HLKFIFDC_00239	411469.EUBHAL_02367	1.05e-171	479.0	COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,24JD4@186801|Clostridia,25W72@186806|Eubacteriaceae	186801|Clostridia	T	phosphatase	stp	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
HLKFIFDC_00240	411469.EUBHAL_02368	0.0	1305.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,25VI6@186806|Eubacteriaceae	186801|Clostridia	KLT	Psort location CytoplasmicMembrane, score	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
HLKFIFDC_00241	411469.EUBHAL_02369	1.49e-216	597.0	COG1162@1|root,COG1162@2|Bacteria,1TPSQ@1239|Firmicutes,248R5@186801|Clostridia,25VS5@186806|Eubacteriaceae	186801|Clostridia	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
HLKFIFDC_00242	411469.EUBHAL_02370	2.8e-159	446.0	COG1564@1|root,COG1564@2|Bacteria,1VA0W@1239|Firmicutes,24NG6@186801|Clostridia,25WFR@186806|Eubacteriaceae	186801|Clostridia	H	thiamine pyrophosphokinase	thiN	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
HLKFIFDC_00243	411469.EUBHAL_02371	1.2e-208	581.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,LRR_5
HLKFIFDC_00244	411469.EUBHAL_02372	7.43e-256	702.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,2482Z@186801|Clostridia,25V14@186806|Eubacteriaceae	186801|Clostridia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
HLKFIFDC_00245	411469.EUBHAL_02374	4.08e-217	598.0	COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,24APG@186801|Clostridia,25WDQ@186806|Eubacteriaceae	186801|Clostridia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
HLKFIFDC_00246	411469.EUBHAL_02375	3.39e-181	504.0	COG1682@1|root,COG1682@2|Bacteria,1UZ1K@1239|Firmicutes,24DBF@186801|Clostridia,25UVJ@186806|Eubacteriaceae	186801|Clostridia	U	ABC-2 type transporter	-	-	-	ko:K09692	ko02010,map02010	M00251	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.104	-	-	ABC2_membrane
HLKFIFDC_00247	411469.EUBHAL_02376	3.38e-169	473.0	COG1134@1|root,COG1134@2|Bacteria,1TQKK@1239|Firmicutes,24A5V@186801|Clostridia,25VYR@186806|Eubacteriaceae	186801|Clostridia	GM	ATPases associated with a variety of cellular activities	-	-	3.6.3.40	ko:K09693	ko02010,map02010	M00251	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.104	-	-	ABC_tran
HLKFIFDC_00248	411469.EUBHAL_02377	4.98e-222	612.0	COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,248B5@186801|Clostridia,25UQQ@186806|Eubacteriaceae	186801|Clostridia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
HLKFIFDC_00249	411469.EUBHAL_02379	5.01e-106	307.0	2E3U8@1|root,32YRK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
HLKFIFDC_00250	411469.EUBHAL_02380	0.0	1275.0	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,248KB@186801|Clostridia,25V2F@186806|Eubacteriaceae	186801|Clostridia	M	Penicillin-binding protein, transpeptidase domain protein	-	-	-	ko:K08384	ko00550,map00550	-	-	-	ko00000,ko00001,ko01011	-	-	-	PBP_dimer,Transpeptidase
HLKFIFDC_00251	411469.EUBHAL_02381	0.0	1097.0	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,248KB@186801|Clostridia,25V2F@186806|Eubacteriaceae	186801|Clostridia	M	Penicillin-binding protein, transpeptidase domain protein	spoVD	-	3.4.16.4	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
HLKFIFDC_00252	411469.EUBHAL_02382	3.92e-220	608.0	COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,247S7@186801|Clostridia,25V83@186806|Eubacteriaceae	186801|Clostridia	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
HLKFIFDC_00253	411469.EUBHAL_02383	0.0	880.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,248GS@186801|Clostridia,25V78@186806|Eubacteriaceae	186801|Clostridia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
HLKFIFDC_00254	411469.EUBHAL_02384	3.3e-260	714.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,25VQI@186806|Eubacteriaceae	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
HLKFIFDC_00255	411469.EUBHAL_02385	4.82e-180	501.0	COG1589@1|root,COG1589@2|Bacteria,1V34X@1239|Firmicutes,248RF@186801|Clostridia,25WR4@186806|Eubacteriaceae	186801|Clostridia	M	COG1589 Cell division septal protein	-	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
HLKFIFDC_00256	411469.EUBHAL_02386	1.65e-263	723.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,25UZZ@186806|Eubacteriaceae	186801|Clostridia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
HLKFIFDC_00258	411469.EUBHAL_02388	1.48e-164	461.0	COG1191@1|root,COG1191@2|Bacteria,1TP3T@1239|Firmicutes,24A4T@186801|Clostridia,25UXX@186806|Eubacteriaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigE	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
HLKFIFDC_00259	411469.EUBHAL_02389	8.22e-177	494.0	COG1191@1|root,COG1191@2|Bacteria,1TPDD@1239|Firmicutes,24A1H@186801|Clostridia,25VP9@186806|Eubacteriaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigG	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
HLKFIFDC_00260	411469.EUBHAL_02391	1.44e-184	513.0	COG1058@1|root,COG1058@2|Bacteria,1UHPB@1239|Firmicutes,25FNU@186801|Clostridia	186801|Clostridia	S	Probable molybdopterin binding domain	cinA	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
HLKFIFDC_00261	411469.EUBHAL_02392	7.1e-275	754.0	COG3633@1|root,COG3633@2|Bacteria,1TPD2@1239|Firmicutes,25CGY@186801|Clostridia,25UX3@186806|Eubacteriaceae	186801|Clostridia	E	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)	sstT	-	-	ko:K07862	-	-	-	-	ko00000,ko02000	2.A.23.4	-	-	SDF
HLKFIFDC_00262	411469.EUBHAL_02393	5.65e-119	340.0	COG1396@1|root,COG1396@2|Bacteria,1V1K5@1239|Firmicutes,24FTC@186801|Clostridia,25WE3@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	puuR	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_19,HTH_3
HLKFIFDC_00263	411469.EUBHAL_02394	5.23e-257	704.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,25V7Z@186806|Eubacteriaceae	186801|Clostridia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.30,3.6.3.31	ko:K02010,ko:K11072	ko02010,map02010	M00190,M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10,3.A.1.11.1	-	-	ABC_tran,TOBE_2
HLKFIFDC_00264	411469.EUBHAL_02395	9.79e-191	530.0	COG1176@1|root,COG1176@2|Bacteria,1TQ7Z@1239|Firmicutes,247Y8@186801|Clostridia,25VTT@186806|Eubacteriaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	potB	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
HLKFIFDC_00265	411469.EUBHAL_02396	4.95e-177	494.0	COG1177@1|root,COG1177@2|Bacteria,1V0VD@1239|Firmicutes,25E3C@186801|Clostridia,25VEB@186806|Eubacteriaceae	186801|Clostridia	E	Binding-protein-dependent transport system inner membrane component	potC	-	-	ko:K02053,ko:K11070	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11,3.A.1.11.1	-	-	BPD_transp_1
HLKFIFDC_00266	411469.EUBHAL_02397	1.04e-268	735.0	COG0687@1|root,COG0687@2|Bacteria,1TPY1@1239|Firmicutes,2483K@186801|Clostridia,25UV9@186806|Eubacteriaceae	186801|Clostridia	P	Bacterial extracellular solute-binding protein	potD	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1,SBP_bac_6,SBP_bac_8
HLKFIFDC_00267	411469.EUBHAL_02398	4.94e-109	314.0	COG0782@1|root,COG0782@2|Bacteria,1V1G3@1239|Firmicutes,24FRJ@186801|Clostridia,25W6D@186806|Eubacteriaceae	186801|Clostridia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA_2	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
HLKFIFDC_00268	1121115.AXVN01000109_gene2346	8.09e-111	319.0	2CAVT@1|root,304CC@2|Bacteria,1V4J6@1239|Firmicutes,24HQA@186801|Clostridia,3Y07W@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2798
HLKFIFDC_00269	742765.HMPREF9457_02927	2.99e-10	57.4	2F3XK@1|root,33WPP@2|Bacteria,1VWC7@1239|Firmicutes	1239|Firmicutes	S	Protein of unknown function (DUF3847)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3847
HLKFIFDC_00270	518637.EUBIFOR_00773	9.27e-14	70.5	COG0358@1|root,COG3598@1|root,COG0358@2|Bacteria,COG3598@2|Bacteria,1TQKP@1239|Firmicutes,3VNYB@526524|Erysipelotrichia	526524|Erysipelotrichia	L	Protein of unknown function (DUF3991)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_25,DUF3991,Toprim_2
HLKFIFDC_00271	411469.EUBHAL_02399	4.42e-249	684.0	COG1609@1|root,COG1609@2|Bacteria,1UYY5@1239|Firmicutes,24C8C@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
HLKFIFDC_00272	411469.EUBHAL_02401	1.39e-255	701.0	COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,248JT@186801|Clostridia,25VIF@186806|Eubacteriaceae	186801|Clostridia	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
HLKFIFDC_00273	411469.EUBHAL_02402	0.0	1119.0	COG1069@1|root,COG1069@2|Bacteria,1TP8T@1239|Firmicutes,248QY@186801|Clostridia,25VIH@186806|Eubacteriaceae	186801|Clostridia	H	Belongs to the ribulokinase family	araB	-	2.7.1.16	ko:K00853	ko00040,ko01100,map00040,map01100	-	R01526,R02439	RC00002,RC00538	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
HLKFIFDC_00274	411469.EUBHAL_02403	1.04e-134	381.0	COG1051@1|root,COG1051@2|Bacteria,1V1P7@1239|Firmicutes,24FSG@186801|Clostridia,25WRZ@186806|Eubacteriaceae	186801|Clostridia	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
HLKFIFDC_00277	471875.RUMLAC_00710	2.7e-71	224.0	COG2963@1|root,COG2963@2|Bacteria,1V4FD@1239|Firmicutes,24GUY@186801|Clostridia,3WPU5@541000|Ruminococcaceae	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_Tnp_1
HLKFIFDC_00278	411469.EUBHAL_03196	0.0	895.0	COG4905@1|root,COG4905@2|Bacteria,1TQUM@1239|Firmicutes,25CKD@186801|Clostridia,25VTI@186806|Eubacteriaceae	186801|Clostridia	S	Putative ABC-transporter type IV	-	-	-	-	-	-	-	-	-	-	-	-	ABC_trans_CmpB
HLKFIFDC_00279	411469.EUBHAL_03195	1.23e-175	490.0	COG2966@1|root,COG2966@2|Bacteria,1TSE8@1239|Firmicutes,24A25@186801|Clostridia,25WXU@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ThrE,ThrE_2
HLKFIFDC_00280	411469.EUBHAL_03194	3.65e-94	275.0	COG3610@1|root,COG3610@2|Bacteria	2|Bacteria	H	response to peptide	-	-	-	-	-	-	-	-	-	-	-	-	ThrE,ThrE_2
HLKFIFDC_00281	411469.EUBHAL_03137	0.0	1527.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25VH6@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	pflB	-	2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
HLKFIFDC_00282	411469.EUBHAL_03138	7.76e-182	505.0	COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,247NA@186801|Clostridia,25VM2@186806|Eubacteriaceae	186801|Clostridia	C	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
HLKFIFDC_00284	1514668.JOOA01000002_gene3162	7.19e-91	290.0	COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,247SB@186801|Clostridia,3WHA6@541000|Ruminococcaceae	186801|Clostridia	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
HLKFIFDC_00285	411469.EUBHAL_01122	0.0	1046.0	COG4108@1|root,COG4108@2|Bacteria,1TPYT@1239|Firmicutes,247X3@186801|Clostridia,25VDE@186806|Eubacteriaceae	186801|Clostridia	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
HLKFIFDC_00286	411469.EUBHAL_01123	1.36e-268	737.0	COG0477@1|root,COG2814@2|Bacteria,1TQXU@1239|Firmicutes,24MJI@186801|Clostridia	186801|Clostridia	EGP	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K08159,ko:K08164	-	-	-	-	ko00000,ko02000	2.A.1.2,2.A.1.2.15,2.A.1.2.18	-	-	MFS_1,Sugar_tr
HLKFIFDC_00288	411469.EUBHAL_01126	0.0	961.0	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1UVHK@1239|Firmicutes,24DE9@186801|Clostridia,25YAP@186806|Eubacteriaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_1
HLKFIFDC_00289	411469.EUBHAL_01127	0.0	945.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia,25UR4@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
HLKFIFDC_00290	411469.EUBHAL_01128	1.4e-234	644.0	COG3481@1|root,COG3481@2|Bacteria,1TPIU@1239|Firmicutes,248SS@186801|Clostridia,25VNH@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	yhaM	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD,tRNA_anti-codon
HLKFIFDC_00291	411469.EUBHAL_01129	1.17e-65	199.0	COG1254@1|root,COG1254@2|Bacteria,1VEM9@1239|Firmicutes,24QXB@186801|Clostridia,25XUI@186806|Eubacteriaceae	186801|Clostridia	C	Belongs to the acylphosphatase family	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
HLKFIFDC_00292	411469.EUBHAL_01130	0.0	1391.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,248YK@186801|Clostridia,25UUQ@186806|Eubacteriaceae	186801|Clostridia	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
HLKFIFDC_00293	411469.EUBHAL_01132	2.88e-116	332.0	COG0219@1|root,COG0219@2|Bacteria,1V3GW@1239|Firmicutes,24HVV@186801|Clostridia,25W60@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
HLKFIFDC_00294	411469.EUBHAL_01133	8.79e-284	775.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,25VAD@186806|Eubacteriaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	aspC	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
HLKFIFDC_00295	411469.EUBHAL_01134	1.18e-109	316.0	COG1522@1|root,COG1522@2|Bacteria,1V3PB@1239|Firmicutes,24I3N@186801|Clostridia,25WGY@186806|Eubacteriaceae	186801|Clostridia	K	Transcriptional regulator, AsnC family	Lrp	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
HLKFIFDC_00296	411469.EUBHAL_01135	1.15e-223	620.0	COG0309@1|root,COG0309@2|Bacteria,1TQP4@1239|Firmicutes,24963@186801|Clostridia,25UTJ@186806|Eubacteriaceae	186801|Clostridia	O	Psort location Cytoplasmic, score	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
HLKFIFDC_00297	411469.EUBHAL_01136	0.0	873.0	COG2720@1|root,COG2720@2|Bacteria,1TSH8@1239|Firmicutes,2493X@186801|Clostridia,25VPP@186806|Eubacteriaceae	186801|Clostridia	V	VanW like protein	-	-	-	ko:K18346	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	G5,PG_binding_4,VanW
HLKFIFDC_00299	411469.EUBHAL_01137	0.0	1303.0	COG1032@1|root,COG1032@2|Bacteria,1TPGT@1239|Firmicutes,247JS@186801|Clostridia,25V6C@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,DUF4080,Radical_SAM
HLKFIFDC_00304	411469.EUBHAL_03220	1.89e-294	803.0	COG4857@1|root,COG4857@2|Bacteria,1TPHY@1239|Firmicutes,249RB@186801|Clostridia,25VMG@186806|Eubacteriaceae	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	mtnK	-	2.7.1.100	ko:K00899	ko00270,ko01100,map00270,map01100	M00034	R04143	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
HLKFIFDC_00306	411469.EUBHAL_03222	6e-59	182.0	COG0640@1|root,COG0640@2|Bacteria,1VEER@1239|Firmicutes,24QZK@186801|Clostridia,25XAB@186806|Eubacteriaceae	186801|Clostridia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	arsR	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
HLKFIFDC_00307	411469.EUBHAL_03223	7.12e-227	625.0	COG1045@1|root,COG1045@2|Bacteria,1TR42@1239|Firmicutes,249SF@186801|Clostridia,25V8W@186806|Eubacteriaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
HLKFIFDC_00308	411469.EUBHAL_03224	0.0	875.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia,25V84@186806|Eubacteriaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HLKFIFDC_00309	411469.EUBHAL_03226	7.46e-85	249.0	2E8UY@1|root,3335C@2|Bacteria,1VI3A@1239|Firmicutes,24RP2@186801|Clostridia	186801|Clostridia	S	TerY-C metal binding domain	-	-	-	-	-	-	-	-	-	-	-	-	TerY_C
HLKFIFDC_00310	411469.EUBHAL_03227	7.99e-193	535.0	COG0631@1|root,COG0631@2|Bacteria,1V75W@1239|Firmicutes,24KMZ@186801|Clostridia	186801|Clostridia	T	Protein phosphatase 2C	-	-	-	-	-	-	-	-	-	-	-	-	PP2C_2
HLKFIFDC_00311	411469.EUBHAL_03228	5.89e-186	517.0	COG4245@1|root,COG4245@2|Bacteria,1V3ER@1239|Firmicutes,24GIK@186801|Clostridia	186801|Clostridia	S	Von Willebrand factor	-	-	-	-	-	-	-	-	-	-	-	-	VWA
HLKFIFDC_00312	411469.EUBHAL_03229	2.2e-296	807.0	COG4248@1|root,COG4248@2|Bacteria,1UZ2E@1239|Firmicutes,24E7G@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00313	411469.EUBHAL_03230	0.0	926.0	COG4248@1|root,COG4248@2|Bacteria,1UZ2E@1239|Firmicutes,24E7G@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
HLKFIFDC_00314	411469.EUBHAL_03231	6.17e-204	565.0	COG4245@1|root,COG4245@2|Bacteria,1V3ER@1239|Firmicutes,24GIK@186801|Clostridia	186801|Clostridia	S	Von Willebrand factor	-	-	-	-	-	-	-	-	-	-	-	-	VWA
HLKFIFDC_00315	411469.EUBHAL_03232	0.0	925.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,2484D@186801|Clostridia,25V9C@186806|Eubacteriaceae	186801|Clostridia	J	Psort location Cytoplasmic, score 10.00	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
HLKFIFDC_00317	411469.EUBHAL_03234	8.24e-43	139.0	2E7X8@1|root,332BT@2|Bacteria,1VG5Y@1239|Firmicutes,24RJD@186801|Clostridia,25ZBZ@186806|Eubacteriaceae	186801|Clostridia	S	Ferredoxin thioredoxin reductase catalytic beta chain	-	-	-	-	-	-	-	-	-	-	-	-	FeThRed_B
HLKFIFDC_00318	411469.EUBHAL_03235	3.69e-231	636.0	COG1102@1|root,COG1102@2|Bacteria,1TSIF@1239|Firmicutes,24BT4@186801|Clostridia,25WSP@186806|Eubacteriaceae	186801|Clostridia	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
HLKFIFDC_00319	411469.EUBHAL_03236	3.03e-187	520.0	2EAC2@1|root,334G5@2|Bacteria,1UK4Q@1239|Firmicutes,24R61@186801|Clostridia,25ZJJ@186806|Eubacteriaceae	186801|Clostridia	S	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,NLPC_P60
HLKFIFDC_00321	411469.EUBHAL_03238	1.18e-139	394.0	COG4186@1|root,COG4186@2|Bacteria,1V40P@1239|Firmicutes,24D6T@186801|Clostridia,25WCV@186806|Eubacteriaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
HLKFIFDC_00322	411469.EUBHAL_03239	2.82e-154	433.0	28PTU@1|root,2ZCEZ@2|Bacteria,1U95M@1239|Firmicutes,247W6@186801|Clostridia,25WSY@186806|Eubacteriaceae	186801|Clostridia	S	Domain of unknown function (DUF4867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4867
HLKFIFDC_00323	411469.EUBHAL_03240	0.0	898.0	COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,247V0@186801|Clostridia,25VHE@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
HLKFIFDC_00324	411469.EUBHAL_03241	1.03e-243	670.0	COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,247W9@186801|Clostridia,25VDT@186806|Eubacteriaceae	186801|Clostridia	C	phosphate acetyltransferase	pta	-	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
HLKFIFDC_00325	411469.EUBHAL_03242	0.0	1038.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,247KT@186801|Clostridia,25V23@186806|Eubacteriaceae	186801|Clostridia	P	Na Pi-cotransporter II-like protein	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
HLKFIFDC_00326	411469.EUBHAL_03243	8.88e-216	596.0	COG0564@1|root,COG0564@2|Bacteria,1TS1T@1239|Firmicutes,249AH@186801|Clostridia,25W73@186806|Eubacteriaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD_2	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
HLKFIFDC_00327	411469.EUBHAL_03244	4.45e-110	318.0	COG0671@1|root,COG0671@2|Bacteria,1VB7J@1239|Firmicutes,24JDD@186801|Clostridia,25X3Y@186806|Eubacteriaceae	186801|Clostridia	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
HLKFIFDC_00330	411469.EUBHAL_03250	0.0	1476.0	COG0366@1|root,COG0366@2|Bacteria,1TNZ0@1239|Firmicutes,247YM@186801|Clostridia,25UWY@186806|Eubacteriaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 13 family	tvaI	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Alpha-amylase_C,Alpha-amylase_N
HLKFIFDC_00331	411469.EUBHAL_03251	0.0	1018.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,247IT@186801|Clostridia,25VHD@186806|Eubacteriaceae	186801|Clostridia	L	Belongs to the DEAD box helicase family	cshA	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
HLKFIFDC_00332	411469.EUBHAL_03252	8.83e-204	563.0	COG0388@1|root,COG0388@2|Bacteria,1TQDK@1239|Firmicutes,24AWV@186801|Clostridia,25VVY@186806|Eubacteriaceae	186801|Clostridia	S	Carbon-nitrogen hydrolase	-	-	3.5.1.3	ko:K13566	ko00250,map00250	-	R00269,R00348	RC00010	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
HLKFIFDC_00333	411469.EUBHAL_03254	4.67e-154	432.0	COG1272@1|root,COG1272@2|Bacteria,1TSFK@1239|Firmicutes,24CPT@186801|Clostridia,25W4H@186806|Eubacteriaceae	186801|Clostridia	S	CytoplasmicMembrane, score 9.99	yqfA	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
HLKFIFDC_00334	411469.EUBHAL_03255	6.86e-60	184.0	COG2827@1|root,COG2827@2|Bacteria,1VEZF@1239|Firmicutes,24QYU@186801|Clostridia,25XBE@186806|Eubacteriaceae	186801|Clostridia	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
HLKFIFDC_00335	411469.EUBHAL_03257	3.55e-160	458.0	COG0739@1|root,COG0739@2|Bacteria,1VATR@1239|Firmicutes,24N76@186801|Clostridia,25WHT@186806|Eubacteriaceae	186801|Clostridia	M	Peptidase, M23 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
HLKFIFDC_00336	457412.RSAG_03136	1.98e-122	359.0	COG5464@1|root,COG5464@2|Bacteria,1TYQI@1239|Firmicutes,24FIE@186801|Clostridia,3WRZY@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_31
HLKFIFDC_00337	411469.EUBHAL_03258	2.62e-218	607.0	COG2385@1|root,COG2385@2|Bacteria,1TQSI@1239|Firmicutes,249H0@186801|Clostridia,25WP6@186806|Eubacteriaceae	186801|Clostridia	D	Stage II sporulation protein	spoIID	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
HLKFIFDC_00338	1235790.C805_01703	1e-32	115.0	2EE4Q@1|root,337ZC@2|Bacteria,1VFIA@1239|Firmicutes,24QTE@186801|Clostridia,25X7R@186806|Eubacteriaceae	186801|Clostridia	S	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
HLKFIFDC_00339	1122172.KB890259_gene1149	2.04e-32	114.0	COG4115@1|root,COG4115@2|Bacteria,37CEK@32066|Fusobacteria	32066|Fusobacteria	S	YoeB-like toxin of bacterial type II toxin-antitoxin system	-	-	-	ko:K19158	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	YoeB_toxin
HLKFIFDC_00340	411469.EUBHAL_03259	1.64e-81	241.0	COG4810@1|root,COG4810@2|Bacteria,1VB54@1239|Firmicutes,24JK9@186801|Clostridia,25WUX@186806|Eubacteriaceae	186801|Clostridia	E	BMC	pduU	-	-	ko:K04031	-	-	-	-	ko00000	-	-	-	BMC
HLKFIFDC_00341	411469.EUBHAL_03260	1.75e-115	330.0	COG4917@1|root,COG4917@2|Bacteria,1VAYC@1239|Firmicutes,24SP8@186801|Clostridia,25YNZ@186806|Eubacteriaceae	186801|Clostridia	E	Ethanolamine utilisation - propanediol utilisation	-	-	-	ko:K04029	-	-	-	-	ko00000	-	-	-	PduV-EutP
HLKFIFDC_00342	411469.EUBHAL_03261	1.4e-303	827.0	COG4857@1|root,COG4857@2|Bacteria,1TPHY@1239|Firmicutes,249RB@186801|Clostridia,25VMG@186806|Eubacteriaceae	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	mtnK	-	2.7.1.100	ko:K00899	ko00270,ko01100,map00270,map01100	M00034	R04143	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
HLKFIFDC_00343	411469.EUBHAL_03262	3.86e-302	823.0	COG4857@1|root,COG4857@2|Bacteria,1TPHY@1239|Firmicutes,249RB@186801|Clostridia,25VMG@186806|Eubacteriaceae	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	mtnK	-	2.7.1.100	ko:K00899	ko00270,ko01100,map00270,map01100	M00034	R04143	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
HLKFIFDC_00344	411469.EUBHAL_00508	5e-20	81.6	2B2ZF@1|root,31VKJ@2|Bacteria,1V9FC@1239|Firmicutes,24P43@186801|Clostridia,25YS1@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00345	411469.EUBHAL_00509	0.0	888.0	COG2340@1|root,COG2340@2|Bacteria	2|Bacteria	S	peptidase inhibitor activity	-	-	-	-	-	-	-	-	-	-	-	-	CAP,Flg_new,LRR_5,SLH,fn3
HLKFIFDC_00347	411469.EUBHAL_00512	1.37e-104	305.0	COG4577@1|root,COG4577@2|Bacteria,1UKDS@1239|Firmicutes,24IS5@186801|Clostridia,25WBX@186806|Eubacteriaceae	186801|Clostridia	CQ	BMC	csoS1C	-	-	-	-	-	-	-	-	-	-	-	BMC
HLKFIFDC_00348	411469.EUBHAL_00513	0.0	888.0	COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24805@186801|Clostridia,25URU@186806|Eubacteriaceae	186801|Clostridia	C	RnfC Barrel sandwich hybrid domain	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_51K,Fer4_17,RnfC_N,SLBB
HLKFIFDC_00349	411469.EUBHAL_00514	0.0	913.0	COG1012@1|root,COG1012@2|Bacteria,1TRGK@1239|Firmicutes,2480V@186801|Clostridia,25UXF@186806|Eubacteriaceae	186801|Clostridia	C	Aldehyde dehydrogenase (NAD) family protein	pduP	-	1.2.1.87	ko:K13922	ko00640,map00640	-	R09097	RC00004,RC00184	ko00000,ko00001,ko01000	-	-	-	Aldedh
HLKFIFDC_00350	411469.EUBHAL_00515	1.24e-233	644.0	COG2096@1|root,COG3193@1|root,COG2096@2|Bacteria,COG3193@2|Bacteria,1V3PI@1239|Firmicutes,24C7G@186801|Clostridia,25VCA@186806|Eubacteriaceae	186801|Clostridia	S	Cobalamin adenosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Cob_adeno_trans,Haem_degrading
HLKFIFDC_00351	411469.EUBHAL_00516	7.91e-55	171.0	COG4576@1|root,COG4576@2|Bacteria,1VEI4@1239|Firmicutes,24QJA@186801|Clostridia,25WU3@186806|Eubacteriaceae	186801|Clostridia	CQ	Ethanolamine utilisation protein EutN/carboxysome	eutN	-	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
HLKFIFDC_00352	411469.EUBHAL_00517	1.34e-201	559.0	COG0452@1|root,COG0452@2|Bacteria,1V24V@1239|Firmicutes,24F67@186801|Clostridia,25W9C@186806|Eubacteriaceae	186801|Clostridia	H	Flavoprotein	-	-	-	-	-	-	-	-	-	-	-	-	Flavoprotein
HLKFIFDC_00353	411469.EUBHAL_00518	2.39e-187	521.0	COG4820@1|root,COG4820@2|Bacteria,1TQVV@1239|Firmicutes,249HD@186801|Clostridia,25VHK@186806|Eubacteriaceae	186801|Clostridia	E	Type IV pilus assembly protein PilM;	eutJ	-	-	ko:K04024	-	-	-	-	ko00000	-	-	-	FtsA,MreB_Mbl,PilM_2
HLKFIFDC_00354	411469.EUBHAL_00519	6.6e-103	307.0	COG3087@1|root,COG4577@1|root,COG3087@2|Bacteria,COG4577@2|Bacteria,1VEIA@1239|Firmicutes,24JTP@186801|Clostridia,25XFB@186806|Eubacteriaceae	186801|Clostridia	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
HLKFIFDC_00355	411469.EUBHAL_00520	3.8e-80	238.0	2EB43@1|root,3354T@2|Bacteria,1VC2J@1239|Firmicutes,24R33@186801|Clostridia,25X32@186806|Eubacteriaceae	186801|Clostridia	S	Dehydratase medium subunit	-	-	-	-	-	-	-	-	-	-	-	-	Dehydratase_MU
HLKFIFDC_00356	411469.EUBHAL_00521	0.0	1151.0	COG0849@1|root,COG0849@2|Bacteria,1TQMU@1239|Firmicutes,24840@186801|Clostridia,25UW8@186806|Eubacteriaceae	186801|Clostridia	D	Diol dehydratase reactivase ATPase-like domain	dhaB4	-	-	-	-	-	-	-	-	-	-	-	DDR
HLKFIFDC_00357	411469.EUBHAL_00522	3.92e-110	317.0	COG4910@1|root,COG4910@2|Bacteria,1V5ZV@1239|Firmicutes,24KHN@186801|Clostridia,25W9N@186806|Eubacteriaceae	186801|Clostridia	Q	Dehydratase small subunit	pduE	-	4.2.1.28,4.2.1.30	ko:K06122,ko:K13920	ko00561,ko00640,map00561,map00640	-	R01047,R02376	RC00429,RC00707	ko00000,ko00001,ko01000	-	-	-	Dehydratase_SU
HLKFIFDC_00358	411469.EUBHAL_00523	3.16e-152	428.0	COG4909@1|root,COG4909@2|Bacteria,1UT3J@1239|Firmicutes,24GDN@186801|Clostridia,25VQS@186806|Eubacteriaceae	186801|Clostridia	Q	Dehydratase medium subunit	pduD	-	4.2.1.28,4.2.1.30	ko:K06121,ko:K13919	ko00561,ko00640,map00561,map00640	-	R01047,R02376	RC00429,RC00707	ko00000,ko00001,ko01000	-	-	-	Dehydratase_MU
HLKFIFDC_00359	411469.EUBHAL_00524	0.0	1092.0	COG4909@1|root,COG4909@2|Bacteria,1TPU7@1239|Firmicutes,24AFR@186801|Clostridia,25V3Z@186806|Eubacteriaceae	186801|Clostridia	Q	Dehydratase large subunit	dhaB	-	4.2.1.28,4.2.1.30	ko:K01699,ko:K06120	ko00561,ko00640,map00561,map00640	-	R01047,R02376	RC00429,RC00707	ko00000,ko00001,ko01000	-	-	-	Dehydratase_LU
HLKFIFDC_00360	411469.EUBHAL_00525	2.39e-186	518.0	COG4816@1|root,COG4816@2|Bacteria,1TTAA@1239|Firmicutes,2498G@186801|Clostridia,25UYN@186806|Eubacteriaceae	186801|Clostridia	E	BMC	pduB	-	-	-	-	-	-	-	-	-	-	-	BMC
HLKFIFDC_00361	411469.EUBHAL_00526	1.01e-52	166.0	COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,25WKA@186806|Eubacteriaceae	186801|Clostridia	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
HLKFIFDC_00362	411469.EUBHAL_00527	2.38e-273	748.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,25US3@186806|Eubacteriaceae	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	-	-	-	ko:K13921	ko00640,map00640	-	R02377	RC00087	ko00000,ko00001	-	-	-	Fe-ADH
HLKFIFDC_00363	411469.EUBHAL_00528	2.26e-245	675.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TSKR@1239|Firmicutes,24AFC@186801|Clostridia,25V1K@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
HLKFIFDC_00364	411469.EUBHAL_00529	4.43e-293	800.0	COG2972@1|root,COG4936@1|root,COG2972@2|Bacteria,COG4936@2|Bacteria,1TPVR@1239|Firmicutes,247XB@186801|Clostridia,25VDS@186806|Eubacteriaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HATPase_c,His_kinase,PocR,dCache_1
HLKFIFDC_00365	411469.EUBHAL_00530	1.24e-154	434.0	COG5012@1|root,COG5012@2|Bacteria,1V1P0@1239|Firmicutes,24G08@186801|Clostridia,25WHI@186806|Eubacteriaceae	186801|Clostridia	S	B12 binding domain	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2
HLKFIFDC_00366	411469.EUBHAL_00532	0.0	1633.0	COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,248E1@186801|Clostridia,25VB4@186806|Eubacteriaceae	186801|Clostridia	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
HLKFIFDC_00367	411469.EUBHAL_00533	0.0	2179.0	COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,247XX@186801|Clostridia,25UTF@186806|Eubacteriaceae	186801|Clostridia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
HLKFIFDC_00369	411469.EUBHAL_00536	0.0	940.0	COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,247NY@186801|Clostridia,25URI@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase,QRPTase_C,QRPTase_N
HLKFIFDC_00370	411469.EUBHAL_00539	3.32e-160	447.0	COG4845@1|root,COG4845@2|Bacteria,1UY81@1239|Firmicutes,24853@186801|Clostridia,25WWG@186806|Eubacteriaceae	186801|Clostridia	V	Chloramphenicol acetyltransferase	cat	-	2.3.1.28	ko:K19271	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	CAT
HLKFIFDC_00371	411469.EUBHAL_00540	4.32e-105	303.0	2AUVQ@1|root,31KJ2@2|Bacteria,1V1UV@1239|Firmicutes,25CWU@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00372	411469.EUBHAL_00541	2.62e-114	327.0	296XG@1|root,2ZU65@2|Bacteria,1V0MN@1239|Firmicutes,24GI1@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3990
HLKFIFDC_00373	411469.EUBHAL_02047	7.43e-295	806.0	COG2851@1|root,COG2851@2|Bacteria,1TQQH@1239|Firmicutes,24A61@186801|Clostridia	186801|Clostridia	C	Citrate transporter	-	-	-	ko:K03300	-	-	-	-	ko00000	2.A.11	-	-	CitMHS
HLKFIFDC_00374	411469.EUBHAL_02048	3.12e-221	610.0	COG0657@1|root,COG0657@2|Bacteria,1V1UH@1239|Firmicutes,248MF@186801|Clostridia,25X98@186806|Eubacteriaceae	186801|Clostridia	I	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
HLKFIFDC_00375	411469.EUBHAL_02050	1.46e-186	519.0	COG0789@1|root,COG0789@2|Bacteria,1UFKB@1239|Firmicutes,24NU1@186801|Clostridia	186801|Clostridia	K	transcriptional regulator, MerR family	-	-	-	-	-	-	-	-	-	-	-	-	MerR
HLKFIFDC_00376	411469.EUBHAL_02052	1.64e-114	328.0	COG1827@1|root,COG1827@2|Bacteria,1V6EY@1239|Firmicutes,24JF2@186801|Clostridia,25WMB@186806|Eubacteriaceae	186801|Clostridia	S	HTH domain protein	niaR	-	-	ko:K07105	-	-	-	-	ko00000	-	-	-	3H,HTH_11
HLKFIFDC_00377	411469.EUBHAL_02053	2.06e-190	530.0	COG0157@1|root,COG0157@2|Bacteria,1TPQC@1239|Firmicutes,248P2@186801|Clostridia,25USE@186806|Eubacteriaceae	186801|Clostridia	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12010	QRPTase_C,QRPTase_N
HLKFIFDC_00378	411469.EUBHAL_02054	6.35e-298	811.0	COG0029@1|root,COG0029@2|Bacteria,1UHSP@1239|Firmicutes,25E6F@186801|Clostridia,25VP8@186806|Eubacteriaceae	186801|Clostridia	H	FAD binding domain	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
HLKFIFDC_00379	411469.EUBHAL_02055	5.81e-219	603.0	COG0379@1|root,COG0379@2|Bacteria,1TP6R@1239|Firmicutes,247IJ@186801|Clostridia,25VC8@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12020	NadA
HLKFIFDC_00380	411469.EUBHAL_02056	5e-138	393.0	2AE9J@1|root,3143R@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00381	411469.EUBHAL_02057	1.3e-157	442.0	COG0745@1|root,COG0745@2|Bacteria,1TPU2@1239|Firmicutes,24B71@186801|Clostridia,25VM1@186806|Eubacteriaceae	186801|Clostridia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HLKFIFDC_00382	411469.EUBHAL_02058	1.08e-305	836.0	COG5002@1|root,COG5002@2|Bacteria,1TPSK@1239|Firmicutes,24A2N@186801|Clostridia,25WC3@186806|Eubacteriaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
HLKFIFDC_00383	411469.EUBHAL_02060	9.07e-55	179.0	2EG7Q@1|root,339ZJ@2|Bacteria,1VJ82@1239|Firmicutes,24SZS@186801|Clostridia,25WVV@186806|Eubacteriaceae	186801|Clostridia	S	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
HLKFIFDC_00384	411469.EUBHAL_02062	0.0	1173.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia,25UZC@186806|Eubacteriaceae	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
HLKFIFDC_00385	411469.EUBHAL_02063	3.15e-135	383.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia,25WMX@186806|Eubacteriaceae	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
HLKFIFDC_00386	411469.EUBHAL_02064	0.0	993.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,248TY@186801|Clostridia,25VVD@186806|Eubacteriaceae	186801|Clostridia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
HLKFIFDC_00387	411469.EUBHAL_02065	0.0	944.0	COG2208@1|root,COG2208@2|Bacteria,1TQ92@1239|Firmicutes,247XG@186801|Clostridia,25VSC@186806|Eubacteriaceae	186801|Clostridia	KT	Serine phosphatase RsbU, regulator of sigma subunit	spoIIE	-	3.1.3.16	ko:K06382	-	-	-	-	ko00000,ko01000	-	-	-	SpoIIE
HLKFIFDC_00391	411469.EUBHAL_02070	1.3e-58	182.0	2E3ZZ@1|root,32YWW@2|Bacteria,1VEIW@1239|Firmicutes,24QNQ@186801|Clostridia,25X2A@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	yabP	-	-	-	-	-	-	-	-	-	-	-	YabP
HLKFIFDC_00392	411469.EUBHAL_02071	2.36e-56	175.0	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,24MM0@186801|Clostridia,25WUG@186806|Eubacteriaceae	186801|Clostridia	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
HLKFIFDC_00393	411469.EUBHAL_02072	1.18e-46	150.0	COG1188@1|root,COG1188@2|Bacteria,1VEI5@1239|Firmicutes,24QNF@186801|Clostridia,25XAD@186806|Eubacteriaceae	186801|Clostridia	J	S4 domain protein	hslR	-	-	-	-	-	-	-	-	-	-	-	S4
HLKFIFDC_00394	411469.EUBHAL_02073	1.14e-119	342.0	COG2002@1|root,COG2002@2|Bacteria,1V02A@1239|Firmicutes,248XR@186801|Clostridia,25WA1@186806|Eubacteriaceae	186801|Clostridia	K	stage V sporulation protein T	spoVT	-	-	ko:K04769	-	-	-	-	ko00000,ko03000	-	-	-	MazE_antitoxin,SpoVT_C
HLKFIFDC_00395	411469.EUBHAL_02074	3.6e-267	731.0	COG0657@1|root,COG0657@2|Bacteria,1UZ7B@1239|Firmicutes,25B2C@186801|Clostridia,25VCD@186806|Eubacteriaceae	186801|Clostridia	I	Pfam:DUF2424	-	-	3.1.1.83	ko:K14731	ko00903,ko00930,ko01220,map00903,map00930,map01220	-	R03751,R06390,R06391,R06392,R06393	RC00713,RC00983,RC01505	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_3
HLKFIFDC_00396	411469.EUBHAL_02075	3.16e-184	512.0	2B3FQ@1|root,31W4P@2|Bacteria,1V6XF@1239|Firmicutes,24KDR@186801|Clostridia,25X3I@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00397	411469.EUBHAL_02076	3.23e-307	837.0	COG4908@1|root,COG4908@2|Bacteria,1TQXH@1239|Firmicutes,24B2C@186801|Clostridia,25VYV@186806|Eubacteriaceae	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	AATase
HLKFIFDC_00398	411469.EUBHAL_01728	7.55e-133	389.0	COG5464@1|root,COG5464@2|Bacteria,1UA0N@1239|Firmicutes,247X9@186801|Clostridia,25WKX@186806|Eubacteriaceae	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
HLKFIFDC_00402	411469.EUBHAL_02077	6.85e-180	501.0	COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,247WW@186801|Clostridia,25V8K@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K05833	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
HLKFIFDC_00403	411469.EUBHAL_02078	1.17e-198	553.0	COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,249P1@186801|Clostridia,25WB6@186806|Eubacteriaceae	186801|Clostridia	S	Branched-chain amino acid ABC transporter, permease protein	-	-	-	ko:K05832	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	BPD_transp_2
HLKFIFDC_00404	411469.EUBHAL_02079	3.53e-231	638.0	COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,248X3@186801|Clostridia,25VZ9@186806|Eubacteriaceae	186801|Clostridia	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
HLKFIFDC_00405	411469.EUBHAL_02080	7.85e-214	591.0	COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,248DH@186801|Clostridia,25UQH@186806|Eubacteriaceae	186801|Clostridia	C	Belongs to the LDH MDH superfamily. LDH family	ldh	-	1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	-	R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
HLKFIFDC_00406	411469.EUBHAL_02082	6.34e-81	240.0	COG3682@1|root,COG3682@2|Bacteria,1VHDV@1239|Firmicutes,25HPH@186801|Clostridia,25Z8X@186806|Eubacteriaceae	1239|Firmicutes	K	Transcriptional regulator, BlaI MecI CopY family	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
HLKFIFDC_00407	411469.EUBHAL_02083	0.0	2254.0	COG4485@1|root,COG4485@2|Bacteria,1TPVY@1239|Firmicutes,24A98@186801|Clostridia,25WP9@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
HLKFIFDC_00408	411469.EUBHAL_02084	0.0	1096.0	COG1376@1|root,COG4733@1|root,COG1376@2|Bacteria,COG4733@2|Bacteria,1V6QN@1239|Firmicutes,24IAP@186801|Clostridia,25XWN@186806|Eubacteriaceae	186801|Clostridia	G	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,SH3_3,YkuD
HLKFIFDC_00409	411469.EUBHAL_02085	1.07e-280	767.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia,25VYN@186806|Eubacteriaceae	186801|Clostridia	E	Belongs to the DegT DnrJ EryC1 family	wecE	-	2.6.1.59	ko:K02805	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	DegT_DnrJ_EryC1
HLKFIFDC_00410	411469.EUBHAL_02086	7.53e-240	659.0	COG0463@1|root,COG0463@2|Bacteria,1TRFA@1239|Firmicutes,249CR@186801|Clostridia,25W1K@186806|Eubacteriaceae	186801|Clostridia	M	Glycosyltransferase like family 2	-	-	2.4.2.53	ko:K10012	ko00520,ko01503,map00520,map01503	M00721,M00761	R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.8	GT2	-	Glycos_transf_2
HLKFIFDC_00411	411469.EUBHAL_02087	6.75e-289	788.0	COG0151@1|root,COG0151@2|Bacteria,1UINU@1239|Firmicutes,25EPG@186801|Clostridia,25ZUJ@186806|Eubacteriaceae	186801|Clostridia	F	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
HLKFIFDC_00412	411469.EUBHAL_02089	0.0	919.0	COG2244@1|root,COG2244@2|Bacteria,1TRRI@1239|Firmicutes,24EFD@186801|Clostridia,25WI4@186806|Eubacteriaceae	186801|Clostridia	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
HLKFIFDC_00413	411469.EUBHAL_02090	0.0	879.0	COG1541@1|root,COG1541@2|Bacteria,1TUII@1239|Firmicutes,25876@186801|Clostridia,25Z2B@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	-
HLKFIFDC_00414	411469.EUBHAL_02091	7.68e-98	289.0	2CA85@1|root,343NM@2|Bacteria,1VPNT@1239|Firmicutes,24V7K@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00415	411469.EUBHAL_02092	6.54e-152	429.0	COG0489@1|root,COG0489@2|Bacteria,1TS4R@1239|Firmicutes,24B0Z@186801|Clostridia,25WFQ@186806|Eubacteriaceae	186801|Clostridia	D	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA
HLKFIFDC_00416	411469.EUBHAL_02093	1.48e-182	509.0	COG3944@1|root,COG3944@2|Bacteria,1UZCR@1239|Firmicutes,24HS8@186801|Clostridia,25WNV@186806|Eubacteriaceae	186801|Clostridia	M	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
HLKFIFDC_00417	411469.EUBHAL_02094	2.72e-238	655.0	COG1316@1|root,COG1316@2|Bacteria,1UY3P@1239|Firmicutes,24H37@186801|Clostridia,25WMN@186806|Eubacteriaceae	186801|Clostridia	K	Cell envelope-related transcriptional attenuator domain	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
HLKFIFDC_00419	411469.EUBHAL_02096	1.01e-164	461.0	COG4464@1|root,COG4464@2|Bacteria,1TQ1T@1239|Firmicutes,24JQU@186801|Clostridia,25XCI@186806|Eubacteriaceae	186801|Clostridia	GM	Capsular polysaccharide biosynthesis protein	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	-
HLKFIFDC_00420	411469.EUBHAL_02098	2.26e-203	564.0	COG0679@1|root,COG0679@2|Bacteria,1UY4N@1239|Firmicutes,24ACC@186801|Clostridia,25XFD@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
HLKFIFDC_00421	411469.EUBHAL_02996	6.1e-82	243.0	2E5GB@1|root,33080@2|Bacteria,1VF18@1239|Firmicutes,24R5R@186801|Clostridia,25XG3@186806|Eubacteriaceae	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	CorC_HlyC
HLKFIFDC_00422	411469.EUBHAL_02998	3.02e-255	698.0	COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,247M9@186801|Clostridia,25USC@186806|Eubacteriaceae	186801|Clostridia	M	UDP-glucose 4-epimerase	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
HLKFIFDC_00423	411469.EUBHAL_03001	2.76e-216	596.0	COG1234@1|root,COG1234@2|Bacteria,1TVEQ@1239|Firmicutes,24FE1@186801|Clostridia	186801|Clostridia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
HLKFIFDC_00424	411469.EUBHAL_03002	2.69e-316	863.0	COG1757@1|root,COG1757@2|Bacteria,1TQ3B@1239|Firmicutes,248WN@186801|Clostridia,25W03@186806|Eubacteriaceae	186801|Clostridia	C	Psort location CytoplasmicMembrane, score 10.00	nhaC	-	-	ko:K03315	-	-	-	-	ko00000,ko02000	2.A.35	-	-	Na_H_antiporter
HLKFIFDC_00425	1121115.AXVN01000077_gene2642	1.02e-20	84.0	2C9RV@1|root,32UDR@2|Bacteria,1VD3D@1239|Firmicutes,24NEV@186801|Clostridia,3Y1XJ@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00426	483218.BACPEC_00200	1.7e-99	292.0	2E73X@1|root,331NC@2|Bacteria,1VI8I@1239|Firmicutes,24R6Z@186801|Clostridia,26BYZ@186813|unclassified Clostridiales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00427	411459.RUMOBE_00600	2.26e-35	135.0	COG1669@1|root,COG4227@1|root,COG4734@1|root,COG1669@2|Bacteria,COG4227@2|Bacteria,COG4734@2|Bacteria,1TQN4@1239|Firmicutes,2482H@186801|Clostridia,3XYTM@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	ArdA,DUF3849,DUF4316,Peptidase_M78,YodL,zf-CHC2
HLKFIFDC_00428	411469.EUBHAL_02513	5.82e-163	457.0	2CJZW@1|root,2ZC29@2|Bacteria,1V2Z2@1239|Firmicutes,24H6F@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00429	500632.CLONEX_02026	1.56e-132	377.0	2BVMK@1|root,32QXV@2|Bacteria,1V9D0@1239|Firmicutes,24K6Z@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
HLKFIFDC_00430	411461.DORFOR_00584	4.2e-157	448.0	COG1209@1|root,COG1209@2|Bacteria,1TPR2@1239|Firmicutes,2490F@186801|Clostridia,27V32@189330|Dorea	186801|Clostridia	M	Psort location Cytoplasmic, score	GalU	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
HLKFIFDC_00432	1235802.C823_02856	5.58e-136	415.0	COG4938@1|root,COG4938@2|Bacteria,1V5VH@1239|Firmicutes,25DQK@186801|Clostridia	186801|Clostridia	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15
HLKFIFDC_00433	1235802.C823_02855	4.03e-45	151.0	COG3600@1|root,COG3600@2|Bacteria,1VARQ@1239|Firmicutes,24UZZ@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF4065)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4065
HLKFIFDC_00434	411469.EUBHAL_02513	2.27e-160	450.0	2CJZW@1|root,2ZC29@2|Bacteria,1V2Z2@1239|Firmicutes,24H6F@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00435	457412.RSAG_01007	8.75e-71	221.0	2BVMK@1|root,32QXV@2|Bacteria,1V9D0@1239|Firmicutes,24K6Z@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
HLKFIFDC_00436	1226325.HMPREF1548_03503	4.51e-206	571.0	COG1209@1|root,COG1209@2|Bacteria,1TPR2@1239|Firmicutes,2490F@186801|Clostridia,36FMD@31979|Clostridiaceae	186801|Clostridia	M	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
HLKFIFDC_00437	411474.COPEUT_00562	3.3e-43	140.0	COG1143@1|root,COG1143@2|Bacteria,1VKVR@1239|Firmicutes,24TV1@186801|Clostridia	186801|Clostridia	C	NADH dehydrogenase subunit I K00338	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_21,Fer4_4,Fer4_7
HLKFIFDC_00438	411474.COPEUT_00563	4.16e-201	561.0	COG1035@1|root,COG1035@2|Bacteria,1TQGA@1239|Firmicutes,249BE@186801|Clostridia	186801|Clostridia	C	Coenzyme F420-reducing hydrogenase beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7,FrhB_FdhB_C,FrhB_FdhB_N
HLKFIFDC_00439	411474.COPEUT_00564	2.28e-205	571.0	COG1035@1|root,COG1035@2|Bacteria,1TQGA@1239|Firmicutes,249BE@186801|Clostridia	186801|Clostridia	C	Coenzyme F420-reducing hydrogenase beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7,FrhB_FdhB_C,FrhB_FdhB_N
HLKFIFDC_00440	411474.COPEUT_00566	1.95e-114	352.0	COG2244@1|root,COG2244@2|Bacteria,1TR7A@1239|Firmicutes,24C7V@186801|Clostridia	186801|Clostridia	S	membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
HLKFIFDC_00441	1183438.GKIL_0284	5.93e-15	83.2	COG2327@1|root,COG2327@2|Bacteria,1G44W@1117|Cyanobacteria	1117|Cyanobacteria	S	Polysaccharide pyruvyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
HLKFIFDC_00442	411474.COPEUT_00570	2.5e-49	180.0	COG3307@1|root,COG3307@2|Bacteria,1VGVE@1239|Firmicutes,24SDV@186801|Clostridia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
HLKFIFDC_00444	1444310.JANV01000021_gene2131	1.49e-39	149.0	COG1216@1|root,COG1216@2|Bacteria,1VATJ@1239|Firmicutes,4IQJ8@91061|Bacilli,1ZRK5@1386|Bacillus	91061|Bacilli	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HLKFIFDC_00445	545243.BAEV01000056_gene205	8.47e-126	375.0	COG1035@1|root,COG1143@1|root,COG1035@2|Bacteria,COG1143@2|Bacteria,1TQGA@1239|Firmicutes,249BE@186801|Clostridia,36GHE@31979|Clostridiaceae	186801|Clostridia	C	hydrogenase beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7,FrhB_FdhB_C,FrhB_FdhB_N
HLKFIFDC_00446	545243.BAEV01000056_gene205	6.47e-83	259.0	COG1035@1|root,COG1143@1|root,COG1035@2|Bacteria,COG1143@2|Bacteria,1TQGA@1239|Firmicutes,249BE@186801|Clostridia,36GHE@31979|Clostridiaceae	186801|Clostridia	C	hydrogenase beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7,FrhB_FdhB_C,FrhB_FdhB_N
HLKFIFDC_00447	457412.RSAG_01019	3.46e-92	288.0	COG0438@1|root,COG0438@2|Bacteria,1TRCM@1239|Firmicutes,24B86@186801|Clostridia,3WIQ7@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyltransferase, group 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
HLKFIFDC_00448	545243.BAEV01000056_gene206	4.89e-129	383.0	COG2327@1|root,COG2327@2|Bacteria,1V4VX@1239|Firmicutes,24C2N@186801|Clostridia,36HW6@31979|Clostridiaceae	186801|Clostridia	M	Polysaccharide pyruvyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
HLKFIFDC_00449	1125712.HMPREF1316_1229	6.02e-54	184.0	COG0438@1|root,COG0438@2|Bacteria,2IJ3Q@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glycos_transf_1
HLKFIFDC_00450	1125712.HMPREF1316_1229	3.61e-80	252.0	COG0438@1|root,COG0438@2|Bacteria,2IJ3Q@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glycos_transf_1
HLKFIFDC_00451	742740.HMPREF9474_01720	0.0	1009.0	COG0438@1|root,COG0535@1|root,COG0438@2|Bacteria,COG0535@2|Bacteria,1UXWS@1239|Firmicutes,247NG@186801|Clostridia,21Y9U@1506553|Lachnoclostridium	186801|Clostridia	C	Iron-sulfur cluster-binding domain	-	-	-	ko:K22227	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
HLKFIFDC_00452	633697.EubceDRAFT1_2494	9.93e-92	283.0	2AIZ3@1|root,319H1@2|Bacteria,1VJ0F@1239|Firmicutes,24QV6@186801|Clostridia	186801|Clostridia	S	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
HLKFIFDC_00453	411463.EUBVEN_01489	1.57e-225	626.0	COG0438@1|root,COG0438@2|Bacteria,1TR0Y@1239|Firmicutes,24B5E@186801|Clostridia,25ZDW@186806|Eubacteriaceae	186801|Clostridia	M	Domain of unknown function (DUF1972)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
HLKFIFDC_00454	500632.CLONEX_02045	8.66e-212	600.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,24870@186801|Clostridia	186801|Clostridia	M	sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
HLKFIFDC_00456	411469.EUBHAL_00221	5.31e-55	172.0	COG2002@1|root,COG2002@2|Bacteria,1VA3H@1239|Firmicutes,24MN7@186801|Clostridia,25XG6@186806|Eubacteriaceae	186801|Clostridia	K	SpoVT / AbrB like domain	abrB	-	-	ko:K06284	-	-	-	-	ko00000,ko03000	-	-	-	MazE_antitoxin
HLKFIFDC_00457	411469.EUBHAL_00222	2.97e-208	575.0	COG1209@1|root,COG1209@2|Bacteria,1V301@1239|Firmicutes,247XE@186801|Clostridia,25UUW@186806|Eubacteriaceae	186801|Clostridia	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
HLKFIFDC_00458	411469.EUBHAL_00223	0.0	1102.0	COG1887@1|root,COG1887@2|Bacteria,1TSTN@1239|Firmicutes,24AA5@186801|Clostridia,25VZJ@186806|Eubacteriaceae	186801|Clostridia	M	teichoic acid biosynthesis protein B	-	-	2.7.8.14,2.7.8.47	ko:K18704	-	-	R11614,R11621	-	ko00000,ko01000	-	-	-	Glycos_transf_2,Glyphos_transf
HLKFIFDC_00459	411469.EUBHAL_00224	0.0	911.0	COG0768@1|root,COG0768@2|Bacteria,1UJPW@1239|Firmicutes,25F83@186801|Clostridia,25XIT@186806|Eubacteriaceae	186801|Clostridia	M	Papain-like cysteine protease AvrRpt2	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2,Peptidase_C70
HLKFIFDC_00460	411469.EUBHAL_00225	3.14e-165	462.0	COG1694@1|root,COG3956@2|Bacteria,1TPK1@1239|Firmicutes,247XM@186801|Clostridia,25VUV@186806|Eubacteriaceae	186801|Clostridia	S	MazG family	mazG	-	3.6.1.66	ko:K02428,ko:K02499	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG,TP_methylase
HLKFIFDC_00461	411469.EUBHAL_00227	6.28e-106	306.0	COG1846@1|root,COG1846@2|Bacteria,1V8EW@1239|Firmicutes,24RW7@186801|Clostridia,25XTG@186806|Eubacteriaceae	186801|Clostridia	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
HLKFIFDC_00462	411469.EUBHAL_00228	0.0	908.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,24865@186801|Clostridia,25VD8@186806|Eubacteriaceae	186801|Clostridia	C	citrate synthase	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
HLKFIFDC_00463	411469.EUBHAL_00229	0.0	966.0	COG0260@1|root,COG0260@2|Bacteria,1TPJZ@1239|Firmicutes,248KF@186801|Clostridia,25Y17@186806|Eubacteriaceae	186801|Clostridia	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
HLKFIFDC_00464	411469.EUBHAL_02503	5.88e-232	639.0	COG2866@1|root,COG2866@2|Bacteria,1TP3K@1239|Firmicutes,249MT@186801|Clostridia,25WZ3@186806|Eubacteriaceae	186801|Clostridia	E	Zn_pept	-	-	3.4.19.11	ko:K01308	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M14
HLKFIFDC_00466	411469.EUBHAL_02502	4.67e-127	361.0	COG1787@1|root,COG1787@2|Bacteria,1VBYF@1239|Firmicutes,24R49@186801|Clostridia,25Z5M@186806|Eubacteriaceae	186801|Clostridia	V	Restriction endonuclease	-	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	Ftsk_gamma,Mrr_cat,zf-C4_Topoisom
HLKFIFDC_00467	411469.EUBHAL_02775	0.0	1098.0	COG0004@1|root,COG0347@1|root,COG0004@2|Bacteria,COG0347@2|Bacteria,1TQYG@1239|Firmicutes,247W1@186801|Clostridia,25VN5@186806|Eubacteriaceae	186801|Clostridia	P	Belongs to the P(II) protein family	amt	-	-	ko:K03320,ko:K06580	-	-	-	-	ko00000,ko02000,ko04090	1.A.11,1.A.11.4	-	-	Ammonium_transp,P-II
HLKFIFDC_00469	411469.EUBHAL_02773	0.0	1096.0	COG0144@1|root,COG3270@1|root,COG0144@2|Bacteria,COG3270@2|Bacteria,1TPGQ@1239|Firmicutes,247N0@186801|Clostridia,25V2B@186806|Eubacteriaceae	186801|Clostridia	J	NOL1 NOP2 sun family	rsmF	-	-	-	-	-	-	-	-	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA,RsmF_methylt_CI
HLKFIFDC_00470	411469.EUBHAL_02772	1.03e-109	317.0	COG0517@1|root,COG0517@2|Bacteria,1V7XE@1239|Firmicutes,24HF5@186801|Clostridia,25XGE@186806|Eubacteriaceae	186801|Clostridia	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
HLKFIFDC_00471	411469.EUBHAL_02770	4.23e-141	398.0	COG1443@1|root,COG1443@2|Bacteria,1V6SB@1239|Firmicutes,24H4F@186801|Clostridia	186801|Clostridia	I	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
HLKFIFDC_00472	411469.EUBHAL_02768	3.26e-88	259.0	2DSCR@1|root,33FK0@2|Bacteria,1VKCD@1239|Firmicutes,24QWS@186801|Clostridia,25XT6@186806|Eubacteriaceae	186801|Clostridia	S	Domain of unknown function (DUF3783)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3783
HLKFIFDC_00473	411469.EUBHAL_02500	2.83e-216	604.0	COG0760@1|root,COG0760@2|Bacteria,1V1WU@1239|Firmicutes,24G3V@186801|Clostridia,25WBW@186806|Eubacteriaceae	186801|Clostridia	O	Parvulin-like peptidyl-prolyl isomerase	-	-	5.2.1.8	ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,SurA_N_3
HLKFIFDC_00474	411469.EUBHAL_02499	0.0	2251.0	COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,248D8@186801|Clostridia,25V0T@186806|Eubacteriaceae	186801|Clostridia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
HLKFIFDC_00475	411469.EUBHAL_02498	0.0	1381.0	COG0193@1|root,COG1887@1|root,COG0193@2|Bacteria,COG1887@2|Bacteria,1V3NB@1239|Firmicutes,24HMC@186801|Clostridia,25W6U@186806|Eubacteriaceae	186801|Clostridia	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
HLKFIFDC_00476	411469.EUBHAL_02496	9.52e-62	189.0	COG2088@1|root,COG2088@2|Bacteria,1V9ZG@1239|Firmicutes,24MVQ@186801|Clostridia,25WUP@186806|Eubacteriaceae	186801|Clostridia	D	Could be involved in septation	spoVG	-	-	ko:K06412	-	-	-	-	ko00000	-	-	-	SpoVG
HLKFIFDC_00477	411469.EUBHAL_02495	5e-254	698.0	COG0448@1|root,COG0448@2|Bacteria,1TPZ3@1239|Firmicutes,2482Q@186801|Clostridia,25V03@186806|Eubacteriaceae	186801|Clostridia	H	Belongs to the bacterial plant glucose-1-phosphate adenylyltransferase family	glgD	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
HLKFIFDC_00478	411469.EUBHAL_02494	2.73e-283	776.0	COG0448@1|root,COG0448@2|Bacteria,1TNZW@1239|Firmicutes,24943@186801|Clostridia,25UUP@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
HLKFIFDC_00479	411469.EUBHAL_02493	0.0	892.0	COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,2484K@186801|Clostridia,25UQR@186806|Eubacteriaceae	186801|Clostridia	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HLKFIFDC_00480	1042156.CXIVA_19120	3.9e-102	357.0	COG4886@1|root,COG5492@1|root,COG4886@2|Bacteria,COG5492@2|Bacteria,1UNG8@1239|Firmicutes,25H2Q@186801|Clostridia	186801|Clostridia	N	Listeria-Bacteroides repeat domain (List_Bact_rpt)	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new
HLKFIFDC_00481	1121897.AUGO01000003_gene2023	4.51e-07	57.8	COG3279@1|root,COG3279@2|Bacteria,4NIYZ@976|Bacteroidetes,1HWVK@117743|Flavobacteriia,2NUPU@237|Flavobacterium	976|Bacteroidetes	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
HLKFIFDC_00482	411469.EUBHAL_02490	3.34e-243	675.0	COG3935@1|root,COG3935@2|Bacteria,1TPR5@1239|Firmicutes,248E7@186801|Clostridia,25VMK@186806|Eubacteriaceae	186801|Clostridia	L	Replication initiation and membrane attachment	dnaD	-	-	-	-	-	-	-	-	-	-	-	DnaB_2
HLKFIFDC_00483	411469.EUBHAL_02489	2.32e-236	650.0	COG1484@1|root,COG1484@2|Bacteria,1TPKM@1239|Firmicutes,2483D@186801|Clostridia,25V61@186806|Eubacteriaceae	186801|Clostridia	L	DNA replication protein	dnaC	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
HLKFIFDC_00484	411469.EUBHAL_02488	2.53e-290	792.0	COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,248ZN@186801|Clostridia,25V08@186806|Eubacteriaceae	186801|Clostridia	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran,Pribosyltran_N
HLKFIFDC_00485	411469.EUBHAL_03211	7.85e-126	364.0	COG5464@1|root,COG5464@2|Bacteria,1V3CA@1239|Firmicutes,24H4R@186801|Clostridia,25ZQ3@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_31
HLKFIFDC_00486	411469.EUBHAL_03211	5.57e-09	55.8	COG5464@1|root,COG5464@2|Bacteria,1V3CA@1239|Firmicutes,24H4R@186801|Clostridia,25ZQ3@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_31
HLKFIFDC_00489	1121098.HMPREF1534_00587	2.26e-89	281.0	COG0641@1|root,COG0641@2|Bacteria,4NVVA@976|Bacteroidetes,2FRE1@200643|Bacteroidia,4ANKC@815|Bacteroidaceae	976|Bacteroidetes	C	radical SAM domain protein	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
HLKFIFDC_00492	877414.ATWA01000150_gene1	8.47e-87	262.0	COG1961@1|root,COG1961@2|Bacteria,1TQAX@1239|Firmicutes,24B05@186801|Clostridia,26AYY@186813|unclassified Clostridiales	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Resolvase
HLKFIFDC_00493	1120998.AUFC01000012_gene468	2.11e-28	104.0	COG3655@1|root,COG3655@2|Bacteria,1VGZ2@1239|Firmicutes,24TD9@186801|Clostridia	186801|Clostridia	K	DNA-binding helix-turn-helix protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26,HTH_3
HLKFIFDC_00494	411469.EUBHAL_02487	0.0	1315.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,248A4@186801|Clostridia,25UUN@186806|Eubacteriaceae	186801|Clostridia	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
HLKFIFDC_00495	411469.EUBHAL_02486	6.3e-174	486.0	2AYHW@1|root,31QMC@2|Bacteria,1V6S7@1239|Firmicutes,24NBV@186801|Clostridia,25WUH@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	TraX
HLKFIFDC_00496	411469.EUBHAL_02485	0.0	1636.0	28IKE@1|root,2Z8M5@2|Bacteria,1TP2B@1239|Firmicutes,248C2@186801|Clostridia,25VUN@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	GcvP	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
HLKFIFDC_00497	411469.EUBHAL_02484	4.5e-280	766.0	COG2263@1|root,COG2263@2|Bacteria,1TQUZ@1239|Firmicutes,248AM@186801|Clostridia,25VBV@186806|Eubacteriaceae	186801|Clostridia	J	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_32
HLKFIFDC_00499	411469.EUBHAL_02482	2.92e-145	410.0	COG0637@1|root,COG0637@2|Bacteria,1VA5Z@1239|Firmicutes,24JNY@186801|Clostridia,25WYY@186806|Eubacteriaceae	186801|Clostridia	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
HLKFIFDC_00500	411469.EUBHAL_02480	1.08e-05	52.0	COG4932@1|root,COG4932@2|Bacteria,1VQ5U@1239|Firmicutes	1239|Firmicutes	M	Cna protein B-type domain	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00502	411469.EUBHAL_02478	1.55e-115	331.0	COG0454@1|root,COG0456@2|Bacteria,1V4FY@1239|Firmicutes,25E88@186801|Clostridia,25WX0@186806|Eubacteriaceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_9
HLKFIFDC_00503	411469.EUBHAL_02476	3.09e-88	259.0	COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,24ND7@186801|Clostridia,25WYB@186806|Eubacteriaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iHN637.CLJU_RS01195	ATP-synt_DE,ATP-synt_DE_N
HLKFIFDC_00504	411469.EUBHAL_02475	0.0	905.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia,25UUG@186806|Eubacteriaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
HLKFIFDC_00505	411469.EUBHAL_02474	2.47e-191	532.0	COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,2486Q@186801|Clostridia,25VH1@186806|Eubacteriaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
HLKFIFDC_00506	411469.EUBHAL_02473	0.0	964.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia,25V5E@186806|Eubacteriaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
HLKFIFDC_00507	411469.EUBHAL_02472	5.1e-121	347.0	COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,24MSA@186801|Clostridia,25WJZ@186806|Eubacteriaceae	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
HLKFIFDC_00508	411469.EUBHAL_02471	2.09e-83	251.0	COG0711@1|root,COG0711@2|Bacteria,1V74H@1239|Firmicutes,25CRV@186801|Clostridia,25ZJA@186806|Eubacteriaceae	186801|Clostridia	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
HLKFIFDC_00509	411469.EUBHAL_02470	2.82e-49	157.0	COG0636@1|root,COG0636@2|Bacteria,1V8SD@1239|Firmicutes,24QMQ@186801|Clostridia,25XKI@186806|Eubacteriaceae	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
HLKFIFDC_00510	411469.EUBHAL_02469	2.59e-161	452.0	COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,24A6Q@186801|Clostridia,25VMP@186806|Eubacteriaceae	186801|Clostridia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
HLKFIFDC_00511	411469.EUBHAL_02468	5.27e-91	266.0	2CFN0@1|root,32RUQ@2|Bacteria,1VD5D@1239|Firmicutes,24MN1@186801|Clostridia,25XZ4@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_I
HLKFIFDC_00512	658088.HMPREF0987_01956	3.31e-05	45.1	2DR0U@1|root,339Q9@2|Bacteria	2|Bacteria	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	atpZ	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
HLKFIFDC_00514	411469.EUBHAL_02465	3.12e-251	689.0	COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,248HS@186801|Clostridia,25UZS@186806|Eubacteriaceae	186801|Clostridia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	sua	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
HLKFIFDC_00515	411469.EUBHAL_02464	3.11e-163	457.0	COG0860@1|root,COG0860@2|Bacteria,1TQ74@1239|Firmicutes,24FT2@186801|Clostridia,25WGE@186806|Eubacteriaceae	186801|Clostridia	M	N-acetylmuramoyl-L-alanine amidase	cwlD	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
HLKFIFDC_00516	411469.EUBHAL_02463	4.23e-178	500.0	COG4862@1|root,COG4862@2|Bacteria,1UZ7D@1239|Firmicutes,24BWV@186801|Clostridia,25WD2@186806|Eubacteriaceae	186801|Clostridia	NOT	Negative regulator of genetic competence	mecB	-	-	ko:K16511	-	-	-	-	ko00000	-	-	-	MecA
HLKFIFDC_00517	411469.EUBHAL_02462	3.36e-42	138.0	COG2846@1|root,COG2846@2|Bacteria,1VET8@1239|Firmicutes,24QPY@186801|Clostridia,25X8I@186806|Eubacteriaceae	186801|Clostridia	D	Hydrid cluster protein-associated redox disulfide domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1858
HLKFIFDC_00518	411469.EUBHAL_02459	2.26e-109	315.0	COG0054@1|root,COG0054@2|Bacteria,1V1DA@1239|Firmicutes,24FRS@186801|Clostridia,25W25@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
HLKFIFDC_00519	411469.EUBHAL_02458	2.77e-292	797.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,248B0@186801|Clostridia,25UWS@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10830	DHBP_synthase,GTP_cyclohydro2
HLKFIFDC_00520	411469.EUBHAL_02457	3.4e-164	459.0	COG0307@1|root,COG0307@2|Bacteria,1V1EP@1239|Firmicutes,24FVK@186801|Clostridia,25W1I@186806|Eubacteriaceae	186801|Clostridia	H	riboflavin synthase, alpha subunit	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
HLKFIFDC_00521	411469.EUBHAL_02456	2.24e-303	826.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia,25V85@186806|Eubacteriaceae	186801|Clostridia	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
HLKFIFDC_00522	411469.EUBHAL_02455	1.34e-136	389.0	COG1033@1|root,COG1033@2|Bacteria,1VHSF@1239|Firmicutes	1239|Firmicutes	P	YARHG	-	-	-	-	-	-	-	-	-	-	-	-	YARHG
HLKFIFDC_00523	411469.EUBHAL_02454	1.69e-18	77.4	COG1148@1|root,COG1148@2|Bacteria,1UI0M@1239|Firmicutes,25E99@186801|Clostridia,25ZK7@186806|Eubacteriaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
HLKFIFDC_00524	411469.EUBHAL_02453	3.55e-162	459.0	COG0789@1|root,COG0789@2|Bacteria,1V4F1@1239|Firmicutes,24NFY@186801|Clostridia,25WJ7@186806|Eubacteriaceae	186801|Clostridia	K	MerR HTH family regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
HLKFIFDC_00525	411469.EUBHAL_02452	3.83e-312	852.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,25VE8@186806|Eubacteriaceae	186801|Clostridia	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
HLKFIFDC_00526	411469.EUBHAL_02451	3.33e-92	270.0	COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,24MT6@186801|Clostridia,25WIG@186806|Eubacteriaceae	186801|Clostridia	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
HLKFIFDC_00527	411469.EUBHAL_02450	0.0	1307.0	COG3887@1|root,COG3887@2|Bacteria,1TPGP@1239|Firmicutes,2484R@186801|Clostridia,25V55@186806|Eubacteriaceae	186801|Clostridia	T	signaling protein consisting of a modified GGDEF domain and a DHH domain	yybT	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
HLKFIFDC_00528	411469.EUBHAL_02449	7.16e-236	650.0	COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,249FA@186801|Clostridia,25WRW@186806|Eubacteriaceae	186801|Clostridia	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10440,ko:K17203	ko02010,map02010	M00212,M00590	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.11,3.A.1.2.13,3.A.1.2.16,3.A.1.2.19	-	-	BPD_transp_2
HLKFIFDC_00529	411469.EUBHAL_02448	0.0	1000.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,25ZMX@186806|Eubacteriaceae	186801|Clostridia	G	ATPases associated with a variety of cellular activities	-	-	-	ko:K17204	ko02010,map02010	M00590	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.11,3.A.1.2.16	-	-	ABC_tran
HLKFIFDC_00530	411469.EUBHAL_02447	2.69e-145	411.0	COG5618@1|root,COG5618@2|Bacteria,1V221@1239|Firmicutes,24G1Q@186801|Clostridia	186801|Clostridia	S	Predicted periplasmic lipoprotein (DUF2291)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2291
HLKFIFDC_00531	411469.EUBHAL_02446	1.81e-230	636.0	COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,247K8@186801|Clostridia,25XEF@186806|Eubacteriaceae	186801|Clostridia	G	Periplasmic binding protein domain	-	-	-	ko:K10439,ko:K17202	ko02010,ko02030,map02010,map02030	M00212,M00590	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.11,3.A.1.2.13,3.A.1.2.16,3.A.1.2.19	-	-	Peripla_BP_4
HLKFIFDC_00532	411469.EUBHAL_02445	0.0	986.0	COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,25VA2@186806|Eubacteriaceae	186801|Clostridia	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
HLKFIFDC_00533	411469.EUBHAL_02444	1.08e-218	603.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia,25USA@186806|Eubacteriaceae	186801|Clostridia	G	Transketolase, pyridine binding domain protein	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
HLKFIFDC_00534	411469.EUBHAL_02443	3.45e-202	559.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,25VDM@186806|Eubacteriaceae	186801|Clostridia	G	Transketolase, thiamine diphosphate binding domain protein	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
HLKFIFDC_00535	411469.EUBHAL_02442	0.0	978.0	COG2407@1|root,COG2407@2|Bacteria,1TQDX@1239|Firmicutes,247N8@186801|Clostridia,25UY7@186806|Eubacteriaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Arabinose_Isome,Fucose_iso_C
HLKFIFDC_00536	411469.EUBHAL_02441	1.53e-245	674.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,25X36@186806|Eubacteriaceae	186801|Clostridia	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
HLKFIFDC_00537	411469.EUBHAL_01065	2.01e-315	860.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,25VJ5@186806|Eubacteriaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HLKFIFDC_00538	411469.EUBHAL_01064	2.74e-213	590.0	COG3965@1|root,COG3965@2|Bacteria,1UZ78@1239|Firmicutes,24BM7@186801|Clostridia,25WR8@186806|Eubacteriaceae	186801|Clostridia	P	cation diffusion facilitator family transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
HLKFIFDC_00540	411469.EUBHAL_01061	4.41e-270	741.0	COG0786@1|root,COG0786@2|Bacteria,1TQA4@1239|Firmicutes,247WX@186801|Clostridia,25V8Y@186806|Eubacteriaceae	186801|Clostridia	P	Catalyzes the sodium-dependent transport of glutamate	gltS	-	-	ko:K03312	-	-	-	-	ko00000,ko02000	2.A.27	-	-	Glt_symporter,NMT1_3
HLKFIFDC_00541	411469.EUBHAL_01060	3.84e-224	619.0	COG2358@1|root,COG2358@2|Bacteria,1TPXW@1239|Firmicutes,2489U@186801|Clostridia,25VC0@186806|Eubacteriaceae	186801|Clostridia	S	TRAP transporter solute receptor, TAXI family	bcsP	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
HLKFIFDC_00542	411469.EUBHAL_01059	0.0	970.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,247SH@186801|Clostridia,25VH2@186806|Eubacteriaceae	186801|Clostridia	O	Psort location Cytoplasmic, score	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA
HLKFIFDC_00543	411469.EUBHAL_01058	5.34e-289	788.0	COG0037@1|root,COG0607@1|root,COG0037@2|Bacteria,COG0607@2|Bacteria,1TQ0Y@1239|Firmicutes,247RP@186801|Clostridia,25VQH@186806|Eubacteriaceae	186801|Clostridia	H	Belongs to the TtcA family	ttcA	-	-	-	-	-	-	-	-	-	-	-	ATP_bind_3,Rhodanese
HLKFIFDC_00544	411469.EUBHAL_01057	4.45e-83	245.0	COG2033@1|root,COG2033@2|Bacteria,1VA34@1239|Firmicutes,24J9I@186801|Clostridia,25WZB@186806|Eubacteriaceae	186801|Clostridia	C	superoxide reductase	dfx	-	1.15.1.2	ko:K05919	-	-	-	-	ko00000,ko01000	-	-	-	Desulfoferrod_N,Desulfoferrodox
HLKFIFDC_00545	411469.EUBHAL_01054	1.52e-103	299.0	COG1846@1|root,COG1846@2|Bacteria,1VBT5@1239|Firmicutes,24MVP@186801|Clostridia,25XI2@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,HTH_27,MarR,MarR_2
HLKFIFDC_00546	411469.EUBHAL_01053	1.63e-300	822.0	COG0534@1|root,COG0534@2|Bacteria,1TPPJ@1239|Firmicutes,25AZE@186801|Clostridia,25V6E@186806|Eubacteriaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HLKFIFDC_00547	411469.EUBHAL_03193	3.76e-275	755.0	COG1301@1|root,COG1301@2|Bacteria,1TP4N@1239|Firmicutes,2494N@186801|Clostridia,25V3F@186806|Eubacteriaceae	186801|Clostridia	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
HLKFIFDC_00548	411469.EUBHAL_00708	5.31e-151	425.0	COG0671@1|root,COG0671@2|Bacteria,1V2PZ@1239|Firmicutes,24DHR@186801|Clostridia,25WT5@186806|Eubacteriaceae	186801|Clostridia	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
HLKFIFDC_00549	411469.EUBHAL_00709	1.64e-201	557.0	COG0688@1|root,COG0688@2|Bacteria,1TR34@1239|Firmicutes,248VU@186801|Clostridia,25VQW@186806|Eubacteriaceae	186801|Clostridia	I	phosphatidylserine decarboxylase	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
HLKFIFDC_00550	411469.EUBHAL_00710	3.63e-159	447.0	COG1183@1|root,COG1183@2|Bacteria,1TTB7@1239|Firmicutes,24GPU@186801|Clostridia,25WGS@186806|Eubacteriaceae	186801|Clostridia	I	Psort location CytoplasmicMembrane, score	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
HLKFIFDC_00551	411469.EUBHAL_00711	1.39e-236	653.0	COG0392@1|root,COG0392@2|Bacteria,1TXG8@1239|Firmicutes,24A1A@186801|Clostridia,25VXA@186806|Eubacteriaceae	186801|Clostridia	S	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
HLKFIFDC_00552	411469.EUBHAL_00713	7.35e-153	432.0	2AYHW@1|root,2Z7XM@2|Bacteria,1UPEA@1239|Firmicutes,25BDY@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	TraX
HLKFIFDC_00553	411469.EUBHAL_00714	6.91e-281	767.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia,25V28@186806|Eubacteriaceae	186801|Clostridia	H	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	tRNA_U5-meth_tr
HLKFIFDC_00554	411469.EUBHAL_00715	2.78e-70	213.0	COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,25WHU@186806|Eubacteriaceae	186801|Clostridia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
HLKFIFDC_00555	411469.EUBHAL_00716	3.86e-114	328.0	COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,24G9R@186801|Clostridia,25W5X@186806|Eubacteriaceae	186801|Clostridia	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
HLKFIFDC_00556	411469.EUBHAL_00718	0.0	901.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,247M5@186801|Clostridia,25UX6@186806|Eubacteriaceae	186801|Clostridia	O	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
HLKFIFDC_00557	411469.EUBHAL_00719	0.0	940.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,248WV@186801|Clostridia,25ZX3@186806|Eubacteriaceae	186801|Clostridia	M	CoA-binding domain	-	-	2.7.8.6	ko:K00996	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	Bac_transf,CoA_binding_3
HLKFIFDC_00558	411469.EUBHAL_00720	3.31e-302	826.0	COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,248RH@186801|Clostridia,25WDT@186806|Eubacteriaceae	186801|Clostridia	K	function transcriptional attenuator common domain	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
HLKFIFDC_00559	411469.EUBHAL_00721	0.0	1949.0	COG0305@1|root,COG0305@2|Bacteria,1W6Y2@1239|Firmicutes,25M5M@186801|Clostridia,25ZAD@186806|Eubacteriaceae	186801|Clostridia	L	Participates in initiation and elongation during chromosome replication	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00560	411469.EUBHAL_00722	1.35e-206	571.0	COG0613@1|root,COG0613@2|Bacteria,1TPI5@1239|Firmicutes,248H2@186801|Clostridia,25VVK@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
HLKFIFDC_00561	411469.EUBHAL_02084	1.05e-50	188.0	COG1376@1|root,COG4733@1|root,COG1376@2|Bacteria,COG4733@2|Bacteria,1V6QN@1239|Firmicutes,24IAP@186801|Clostridia,25XWN@186806|Eubacteriaceae	186801|Clostridia	G	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,SH3_3,YkuD
HLKFIFDC_00562	411469.EUBHAL_00725	1.11e-265	726.0	COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,247YV@186801|Clostridia,25VKX@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
HLKFIFDC_00563	411469.EUBHAL_00726	2.05e-153	431.0	COG3619@1|root,COG3619@2|Bacteria,1V1VQ@1239|Firmicutes,24DUE@186801|Clostridia,25WCR@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1275
HLKFIFDC_00564	411469.EUBHAL_00655	3.64e-306	837.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,25VVF@186806|Eubacteriaceae	186801|Clostridia	V	MATE efflux family protein	mepA_2	-	-	-	-	-	-	-	-	-	-	-	MatE
HLKFIFDC_00565	411469.EUBHAL_00656	5.53e-77	229.0	COG0640@1|root,COG0640@2|Bacteria,1VINN@1239|Firmicutes,24S2F@186801|Clostridia	186801|Clostridia	K	transcriptional regulator, ArsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
HLKFIFDC_00566	411469.EUBHAL_00658	5.06e-254	699.0	COG0628@1|root,COG0628@2|Bacteria,1TQBF@1239|Firmicutes,25CCK@186801|Clostridia,25VHJ@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
HLKFIFDC_00567	411469.EUBHAL_00659	2.87e-217	600.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,25VWS@186806|Eubacteriaceae	186801|Clostridia	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
HLKFIFDC_00568	411469.EUBHAL_00660	1.85e-69	209.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,25Z86@186806|Eubacteriaceae	186801|Clostridia	O	Thioredoxin-like domain	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
HLKFIFDC_00569	411469.EUBHAL_00661	0.0	1347.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,25WJ1@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	1.6.99.1	ko:K00354	-	-	R00282	RC00001	ko00000,ko01000	-	-	-	Oxidored_FMN,Pyr_redox_2
HLKFIFDC_00570	411469.EUBHAL_00662	3.56e-113	324.0	COG1051@1|root,COG1051@2|Bacteria,1V3IM@1239|Firmicutes,24HEA@186801|Clostridia,25WKI@186806|Eubacteriaceae	186801|Clostridia	F	NUDIX domain	mutX	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
HLKFIFDC_00571	411469.EUBHAL_00663	2.74e-196	547.0	COG0679@1|root,COG0679@2|Bacteria,1UYFH@1239|Firmicutes,24AI3@186801|Clostridia,25ZPN@186806|Eubacteriaceae	186801|Clostridia	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
HLKFIFDC_00572	411462.DORLON_01306	6.52e-89	265.0	COG1853@1|root,COG1853@2|Bacteria,1UYJS@1239|Firmicutes,25KHT@186801|Clostridia,27WY0@189330|Dorea	186801|Clostridia	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
HLKFIFDC_00573	1232453.BAIF02000008_gene3011	6.7e-299	823.0	COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,247NR@186801|Clostridia,2690R@186813|unclassified Clostridiales	186801|Clostridia	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
HLKFIFDC_00574	568816.Acin_2029	7.88e-158	465.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,4H2AM@909932|Negativicutes	909932|Negativicutes	E	amino acid carrier protein	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
HLKFIFDC_00575	1232452.BAIB02000008_gene1891	3.79e-74	235.0	COG1143@1|root,COG1143@2|Bacteria,1TQ16@1239|Firmicutes,24D0I@186801|Clostridia	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_BFD,Fer4,Fer4_10
HLKFIFDC_00576	1449126.JQKL01000044_gene1997	3.3e-138	405.0	COG0446@1|root,COG0446@2|Bacteria,1TQH5@1239|Firmicutes,247YR@186801|Clostridia,267Z9@186813|unclassified Clostridiales	186801|Clostridia	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Pyr_redox_2,Pyr_redox_3
HLKFIFDC_00577	1449126.JQKL01000044_gene1996	2.79e-41	138.0	COG3383@1|root,COG3383@2|Bacteria,1VAVK@1239|Firmicutes,24MYJ@186801|Clostridia	186801|Clostridia	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4
HLKFIFDC_00578	511.JT27_05250	7.89e-41	155.0	COG0665@1|root,COG0665@2|Bacteria,1MXM0@1224|Proteobacteria,2VPM8@28216|Betaproteobacteria,3T2WK@506|Alcaligenaceae	28216|Betaproteobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
HLKFIFDC_00579	1232452.BAIB02000008_gene1889	8.36e-81	253.0	COG0329@1|root,COG0329@2|Bacteria,1TPVS@1239|Firmicutes,24DC8@186801|Clostridia	186801|Clostridia	E	Dihydrodipicolinate synthetase family	-	-	-	-	-	-	-	-	-	-	-	-	DHDPS
HLKFIFDC_00580	1232453.BAIF02000008_gene3010	1.26e-85	259.0	COG2070@1|root,COG2070@2|Bacteria,1V4I9@1239|Firmicutes,24IN1@186801|Clostridia	186801|Clostridia	S	2-Nitropropane dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00581	1232453.BAIF02000008_gene3007	2.45e-55	184.0	COG1349@1|root,COG1349@2|Bacteria,1VXPJ@1239|Firmicutes	1239|Firmicutes	GK	DeoR C terminal sensor domain	-	-	-	-	-	-	-	-	-	-	-	-	DeoRC
HLKFIFDC_00582	411469.EUBHAL_00666	1.43e-129	368.0	COG4636@1|root,COG4636@2|Bacteria,1V8DJ@1239|Firmicutes,24G93@186801|Clostridia,25WD7@186806|Eubacteriaceae	186801|Clostridia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
HLKFIFDC_00583	411469.EUBHAL_00667	3.75e-243	668.0	COG1638@1|root,COG1638@2|Bacteria,1TP3I@1239|Firmicutes,248MN@186801|Clostridia,25XCE@186806|Eubacteriaceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein, family 7	siaP	-	-	ko:K21395	-	-	-	-	ko00000,ko02000	2.A.56.1	-	-	DctP
HLKFIFDC_00584	411469.EUBHAL_00668	8.81e-285	781.0	COG1593@1|root,COG1593@2|Bacteria,1TPNU@1239|Firmicutes,248BY@186801|Clostridia,25VRS@186806|Eubacteriaceae	186801|Clostridia	G	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DctM,DctQ
HLKFIFDC_00585	411469.EUBHAL_00669	4.94e-109	314.0	COG3090@1|root,COG3090@2|Bacteria,1V3PZ@1239|Firmicutes,24HA7@186801|Clostridia	186801|Clostridia	G	COG COG3090 TRAP-type C4-dicarboxylate transport system, small permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
HLKFIFDC_00586	411469.EUBHAL_00670	6.36e-295	806.0	COG0477@1|root,COG2814@2|Bacteria,1UNUP@1239|Firmicutes,25FJG@186801|Clostridia	186801|Clostridia	EGP	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HLKFIFDC_00587	411469.EUBHAL_00671	3.88e-207	573.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia,25UXV@186806|Eubacteriaceae	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI,Shikimate_DH,Shikimate_dh_N
HLKFIFDC_00588	411469.EUBHAL_00672	0.0	1301.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,25VG3@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
HLKFIFDC_00589	411469.EUBHAL_00673	7.27e-206	568.0	COG1082@1|root,COG1082@2|Bacteria,1TT50@1239|Firmicutes,248RM@186801|Clostridia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
HLKFIFDC_00590	411469.EUBHAL_00674	1.57e-217	601.0	COG0583@1|root,COG0583@2|Bacteria,1TRVX@1239|Firmicutes,24B1W@186801|Clostridia,25XB8@186806|Eubacteriaceae	186801|Clostridia	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
HLKFIFDC_00591	411469.EUBHAL_00676	1.68e-227	626.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia,25UXV@186806|Eubacteriaceae	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI,Shikimate_DH,Shikimate_dh_N
HLKFIFDC_00592	411469.EUBHAL_00677	8.21e-159	446.0	COG1811@1|root,COG1811@2|Bacteria,1TQWV@1239|Firmicutes,25CHE@186801|Clostridia,25ZSU@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF554)	-	-	-	ko:K07150	-	-	-	-	ko00000	-	-	-	DUF554
HLKFIFDC_00593	411469.EUBHAL_00679	2.56e-122	351.0	2EH19@1|root,33AT9@2|Bacteria,1VKP2@1239|Firmicutes,24VHB@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00594	411469.EUBHAL_00680	9.14e-148	418.0	2D319@1|root,33MQT@2|Bacteria,1VFT6@1239|Firmicutes,24SFU@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF1700)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1700
HLKFIFDC_00595	411469.EUBHAL_00681	2.03e-67	204.0	COG1695@1|root,COG1695@2|Bacteria,1VAKA@1239|Firmicutes,24MVF@186801|Clostridia,25X5I@186806|Eubacteriaceae	186801|Clostridia	K	Transcriptional regulator PadR-like family	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
HLKFIFDC_00596	411469.EUBHAL_01556	1.23e-175	490.0	COG0710@1|root,COG0710@2|Bacteria,1TSPN@1239|Firmicutes,249EX@186801|Clostridia,25WDC@186806|Eubacteriaceae	186801|Clostridia	E	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate	aroD	-	4.2.1.10	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I,SKI
HLKFIFDC_00597	411469.EUBHAL_01555	5.54e-209	577.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia,25UXV@186806|Eubacteriaceae	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI,Shikimate_DH,Shikimate_dh_N
HLKFIFDC_00598	411469.EUBHAL_01554	2.91e-183	510.0	COG0703@1|root,COG1605@1|root,COG0703@2|Bacteria,COG1605@2|Bacteria,1VA6Z@1239|Firmicutes,24MQY@186801|Clostridia,25WIY@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,SKI
HLKFIFDC_00599	411469.EUBHAL_01549	2.78e-139	395.0	COG1802@1|root,COG1802@2|Bacteria,1TS3S@1239|Firmicutes,24DBG@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
HLKFIFDC_00600	411469.EUBHAL_01548	2.5e-139	394.0	COG1802@1|root,COG1802@2|Bacteria,1VH73@1239|Firmicutes,24SWG@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
HLKFIFDC_00601	411469.EUBHAL_03197	1.3e-95	278.0	COG1310@1|root,COG1310@2|Bacteria,1V6TY@1239|Firmicutes,24JI8@186801|Clostridia,25X1S@186806|Eubacteriaceae	186801|Clostridia	S	metal-dependent protease of the PAD1 JAB1 superfamily	-	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
HLKFIFDC_00602	411469.EUBHAL_03198	2.3e-187	521.0	COG0476@1|root,COG0476@2|Bacteria,1TQ3U@1239|Firmicutes,25CJC@186801|Clostridia,25V2C@186806|Eubacteriaceae	186801|Clostridia	H	ThiF family	moeB	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
HLKFIFDC_00603	411469.EUBHAL_03199	1.69e-37	126.0	COG2104@1|root,COG2104@2|Bacteria,1VFJR@1239|Firmicutes,24SEU@186801|Clostridia,25XIY@186806|Eubacteriaceae	186801|Clostridia	H	THIamine biosynthesis	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
HLKFIFDC_00604	411469.EUBHAL_03200	1.48e-65	199.0	COG0526@1|root,COG0526@2|Bacteria,1TTVH@1239|Firmicutes,25N66@186801|Clostridia,25Z55@186806|Eubacteriaceae	186801|Clostridia	CO	Thioredoxin	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
HLKFIFDC_00605	411469.EUBHAL_03201	1.61e-52	165.0	COG0425@1|root,COG0425@2|Bacteria,1VBET@1239|Firmicutes,24NV0@186801|Clostridia,25XMJ@186806|Eubacteriaceae	186801|Clostridia	O	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	TusA
HLKFIFDC_00606	411469.EUBHAL_03202	9.01e-195	541.0	COG2221@1|root,COG2221@2|Bacteria,1TR7P@1239|Firmicutes,2493K@186801|Clostridia,25UZE@186806|Eubacteriaceae	186801|Clostridia	C	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,NIR_SIR,NIR_SIR_ferr
HLKFIFDC_00607	411469.EUBHAL_03203	6.04e-291	795.0	COG2873@1|root,COG2873@2|Bacteria,1TXZ1@1239|Firmicutes,248M7@186801|Clostridia,25VC2@186806|Eubacteriaceae	186801|Clostridia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
HLKFIFDC_00608	411469.EUBHAL_03204	0.0	1026.0	COG2895@1|root,COG2895@2|Bacteria,1UI8R@1239|Firmicutes,249BX@186801|Clostridia,25VWU@186806|Eubacteriaceae	186801|Clostridia	H	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
HLKFIFDC_00609	411469.EUBHAL_03205	1.81e-221	610.0	COG0175@1|root,COG0175@2|Bacteria,1U1VN@1239|Firmicutes,248Y9@186801|Clostridia,25VBR@186806|Eubacteriaceae	186801|Clostridia	H	Psort location Cytoplasmic, score	cysD	-	1.8.4.10,1.8.4.8,2.7.7.4	ko:K00390,ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R02021,R04929	RC00007,RC02809,RC02862,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
HLKFIFDC_00610	411469.EUBHAL_03206	7.29e-75	223.0	COG1146@1|root,COG1146@2|Bacteria,1VADW@1239|Firmicutes,24MQA@186801|Clostridia,25X48@186806|Eubacteriaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	1.8.99.2	ko:K00395	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_9
HLKFIFDC_00611	411469.EUBHAL_03207	0.0	1139.0	COG1053@1|root,COG1053@2|Bacteria,1TRE8@1239|Firmicutes,247TH@186801|Clostridia,25VSD@186806|Eubacteriaceae	186801|Clostridia	C	FAD binding domain	aprA	-	1.8.99.2	ko:K00394	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
HLKFIFDC_00612	411469.EUBHAL_03208	9.54e-97	282.0	COG1959@1|root,COG1959@2|Bacteria,1VAW8@1239|Firmicutes,24PEY@186801|Clostridia,25WXX@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
HLKFIFDC_00613	411469.EUBHAL_03209	1.32e-219	606.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,2497G@186801|Clostridia,25UVD@186806|Eubacteriaceae	186801|Clostridia	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
HLKFIFDC_00614	411469.EUBHAL_03212	8.06e-96	279.0	COG1959@1|root,COG1959@2|Bacteria,1V3QB@1239|Firmicutes,24JIV@186801|Clostridia,25WZC@186806|Eubacteriaceae	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
HLKFIFDC_00615	411469.EUBHAL_03213	1.03e-205	570.0	COG0583@1|root,COG0583@2|Bacteria,1TP6T@1239|Firmicutes,24970@186801|Clostridia,25WDP@186806|Eubacteriaceae	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
HLKFIFDC_00616	411469.EUBHAL_03214	9.43e-139	393.0	COG2059@1|root,COG2059@2|Bacteria,1V22C@1239|Firmicutes,24G7P@186801|Clostridia,25WRC@186806|Eubacteriaceae	186801|Clostridia	P	Chromate transporter	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
HLKFIFDC_00617	411469.EUBHAL_03215	1.09e-123	353.0	COG2059@1|root,COG2059@2|Bacteria,1V42U@1239|Firmicutes,24HA0@186801|Clostridia,25WPT@186806|Eubacteriaceae	186801|Clostridia	P	CytoplasmicMembrane, score 9.99	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
HLKFIFDC_00618	411469.EUBHAL_03216	9.01e-197	546.0	COG1760@1|root,COG1760@2|Bacteria,1TP79@1239|Firmicutes,2480J@186801|Clostridia,25V22@186806|Eubacteriaceae	186801|Clostridia	E	L-serine dehydratase, iron-sulfur-dependent, alpha subunit	sdaAA	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha
HLKFIFDC_00619	411469.EUBHAL_03217	5.04e-155	435.0	COG1760@1|root,COG1760@2|Bacteria,1U8TZ@1239|Firmicutes,24AEE@186801|Clostridia,25VBT@186806|Eubacteriaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	sdaAB	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	ACT,SDH_beta
HLKFIFDC_00620	411469.EUBHAL_00110	2.84e-150	422.0	COG1309@1|root,COG1309@2|Bacteria,1UR73@1239|Firmicutes,25BIY@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HLKFIFDC_00621	411469.EUBHAL_00108	1.11e-52	166.0	COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,24QIP@186801|Clostridia,25X7H@186806|Eubacteriaceae	186801|Clostridia	G	PTS HPr component phosphorylation site	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
HLKFIFDC_00622	411469.EUBHAL_00107	0.0	866.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,25V7V@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
HLKFIFDC_00623	411469.EUBHAL_02658	4.64e-171	478.0	COG1116@1|root,COG1116@2|Bacteria,1TSW5@1239|Firmicutes,25AZG@186801|Clostridia,25ZHW@186806|Eubacteriaceae	186801|Clostridia	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
HLKFIFDC_00624	411469.EUBHAL_02657	5.01e-254	696.0	COG0715@1|root,COG0715@2|Bacteria,1TPAD@1239|Firmicutes,24A2V@186801|Clostridia,25V0S@186806|Eubacteriaceae	186801|Clostridia	P	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
HLKFIFDC_00625	411469.EUBHAL_02656	1.36e-144	410.0	COG0600@1|root,COG0600@2|Bacteria,1TRFD@1239|Firmicutes,25C7Z@186801|Clostridia,25WH8@186806|Eubacteriaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
HLKFIFDC_00626	411469.EUBHAL_02655	1.86e-63	194.0	COG0011@1|root,COG0011@2|Bacteria,1VC4R@1239|Firmicutes,24MY3@186801|Clostridia,25XHN@186806|Eubacteriaceae	186801|Clostridia	S	Thiamine-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
HLKFIFDC_00627	411469.EUBHAL_02654	0.0	885.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,25UUS@186806|Eubacteriaceae	186801|Clostridia	E	amino acid carrier protein	agcS_2	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
HLKFIFDC_00628	411469.EUBHAL_02653	8.29e-294	806.0	COG0534@1|root,COG0534@2|Bacteria,1TQ56@1239|Firmicutes,248YU@186801|Clostridia,25VSM@186806|Eubacteriaceae	186801|Clostridia	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HLKFIFDC_00629	1504823.CCMM01000008_gene974	0.0	897.0	COG1132@1|root,COG1132@2|Bacteria,2NNVD@2323|unclassified Bacteria	2|Bacteria	V	ABC transporter	-	-	3.6.3.25	ko:K06020,ko:K06147	-	-	-	-	ko00000,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HLKFIFDC_00630	483218.BACPEC_01216	0.0	892.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247VZ@186801|Clostridia,268EH@186813|unclassified Clostridiales	186801|Clostridia	V	COG COG1132 ABC-type multidrug transport system, ATPase and permease components	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HLKFIFDC_00631	411489.CLOL250_01725	1.07e-84	256.0	COG1309@1|root,COG1309@2|Bacteria,1TT2J@1239|Firmicutes,24A5X@186801|Clostridia,36IPI@31979|Clostridiaceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HLKFIFDC_00632	411469.EUBHAL_02651	3.59e-153	429.0	COG2315@1|root,COG3695@1|root,COG2315@2|Bacteria,COG3695@2|Bacteria,1VVT6@1239|Firmicutes,25EAU@186801|Clostridia,25VHV@186806|Eubacteriaceae	186801|Clostridia	H	6-O-methylguanine DNA methyltransferase, DNA binding domain	ogt	-	-	-	-	-	-	-	-	-	-	-	DNA_binding_1,YjbR
HLKFIFDC_00633	411469.EUBHAL_02650	4.62e-107	331.0	COG1879@1|root,COG2199@1|root,COG1879@2|Bacteria,COG3706@2|Bacteria,1UK20@1239|Firmicutes,25FNV@186801|Clostridia	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
HLKFIFDC_00634	411469.EUBHAL_02650	2.08e-156	451.0	COG1879@1|root,COG2199@1|root,COG1879@2|Bacteria,COG3706@2|Bacteria,1UK20@1239|Firmicutes,25FNV@186801|Clostridia	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
HLKFIFDC_00635	411469.EUBHAL_02649	4.68e-153	430.0	COG2304@1|root,COG2304@2|Bacteria,1TRPP@1239|Firmicutes,249HV@186801|Clostridia,25VGG@186806|Eubacteriaceae	186801|Clostridia	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00636	411469.EUBHAL_02993	5.53e-242	665.0	COG2110@1|root,COG2110@2|Bacteria,1TPCU@1239|Firmicutes,24ARG@186801|Clostridia,25UV0@186806|Eubacteriaceae	186801|Clostridia	S	phosphatase homologous to the C-terminal domain of histone macroH2A1	-	-	-	-	-	-	-	-	-	-	-	-	Macro
HLKFIFDC_00637	411469.EUBHAL_02145	2.28e-125	357.0	2C2RJ@1|root,33VFU@2|Bacteria,1VV8Z@1239|Firmicutes,250DV@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00638	411461.DORFOR_03054	4.65e-13	68.6	COG4823@1|root,COG4823@2|Bacteria,1V4ZD@1239|Firmicutes,24IEC@186801|Clostridia,27VHG@189330|Dorea	186801|Clostridia	V	COG COG4823 Abortive infection bacteriophage resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	Abi_2
HLKFIFDC_00639	411469.EUBHAL_02143	1.52e-240	660.0	COG0846@1|root,COG0846@2|Bacteria,1TQB7@1239|Firmicutes,247UN@186801|Clostridia,25VAE@186806|Eubacteriaceae	186801|Clostridia	K	COG COG0846 NAD-dependent protein deacetylases, SIR2 family	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00640	411469.EUBHAL_02142	6.2e-204	564.0	COG0846@1|root,COG0846@2|Bacteria,1TQB7@1239|Firmicutes,247UN@186801|Clostridia,25VAE@186806|Eubacteriaceae	186801|Clostridia	K	COG COG0846 NAD-dependent protein deacetylases, SIR2 family	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00641	1280698.AUJS01000042_gene3263	2.56e-99	288.0	COG1959@1|root,COG1959@2|Bacteria,1V34F@1239|Firmicutes,24H42@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
HLKFIFDC_00642	397288.C806_00111	2.81e-40	142.0	COG4823@1|root,COG4823@2|Bacteria,1V4ZD@1239|Firmicutes,24IEC@186801|Clostridia,27THJ@186928|unclassified Lachnospiraceae	186801|Clostridia	V	Abi-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abi_2
HLKFIFDC_00643	411469.EUBHAL_02136	3.91e-224	618.0	COG4823@1|root,COG4823@2|Bacteria,1UY67@1239|Firmicutes,24CBG@186801|Clostridia,25X3C@186806|Eubacteriaceae	186801|Clostridia	V	Abi-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abi_2
HLKFIFDC_00644	411463.EUBVEN_00921	3.42e-10	55.5	2E3ZC@1|root,32YWA@2|Bacteria,1VHZW@1239|Firmicutes,24SMN@186801|Clostridia,25XQP@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00645	1280698.AUJS01000077_gene3305	5.06e-138	399.0	COG1668@1|root,COG1668@2|Bacteria,1UY5S@1239|Firmicutes,24DP3@186801|Clostridia,27VKC@189330|Dorea	186801|Clostridia	CP	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
HLKFIFDC_00646	411490.ANACAC_00756	2.65e-46	165.0	COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,2487V@186801|Clostridia	186801|Clostridia	L	DNA polymerase	-	-	2.7.7.7	ko:K02334	-	-	-	-	ko00000,ko01000	-	-	-	DNA_pol_A
HLKFIFDC_00648	411490.ANACAC_00758	7.32e-124	353.0	28J2E@1|root,2Z8YX@2|Bacteria,1TRF9@1239|Firmicutes,249U3@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF2815)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2815
HLKFIFDC_00649	1235802.C823_01496	4.22e-53	177.0	COG2887@1|root,COG2887@2|Bacteria,1TPIC@1239|Firmicutes,247TB@186801|Clostridia,25V8B@186806|Eubacteriaceae	186801|Clostridia	L	Protein of unknown function (DUF2800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2800
HLKFIFDC_00650	411490.ANACAC_00759	5.93e-170	481.0	COG2887@1|root,COG2887@2|Bacteria,1TPIC@1239|Firmicutes,247TB@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2800
HLKFIFDC_00651	476272.RUMHYD_01446	3.48e-08	52.4	2A43P@1|root,30SNR@2|Bacteria,1UFAS@1239|Firmicutes,25NPR@186801|Clostridia,3Y0WV@572511|Blautia	186801|Clostridia	S	COG NOG23194 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00653	1121342.AUCO01000004_gene616	3.24e-23	90.5	2E1NS@1|root,32WZM@2|Bacteria,1VACR@1239|Firmicutes,24Q9G@186801|Clostridia,36UGA@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00654	1345695.CLSA_c09130	4.88e-47	157.0	COG1595@1|root,COG1595@2|Bacteria,1V1E8@1239|Firmicutes,24FSF@186801|Clostridia,36I93@31979|Clostridiaceae	186801|Clostridia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4,Sigma70_r4_2
HLKFIFDC_00655	397288.C806_04955	0.0	1025.0	COG5635@1|root,COG5635@2|Bacteria,1V0NR@1239|Firmicutes,24890@186801|Clostridia,27S3F@186928|unclassified Lachnospiraceae	186801|Clostridia	T	Nacht domain	-	-	-	-	-	-	-	-	-	-	-	-	NACHT
HLKFIFDC_00656	397288.C806_04954	1.6e-32	113.0	COG3655@1|root,COG3655@2|Bacteria,1VEM0@1239|Firmicutes,24QPN@186801|Clostridia,27PYV@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
HLKFIFDC_00657	397288.C806_04953	8.46e-236	653.0	2CXRX@1|root,32T2G@2|Bacteria,1VQWD@1239|Firmicutes,24988@186801|Clostridia,27RXR@186928|unclassified Lachnospiraceae	186801|Clostridia	L	NgoFVII restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	RE_NgoFVII
HLKFIFDC_00658	397288.C806_04952	0.0	1025.0	COG0610@1|root,COG0610@2|Bacteria,1UIN3@1239|Firmicutes,25ENP@186801|Clostridia	186801|Clostridia	V	Z1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Z1
HLKFIFDC_00659	397288.C806_04951	2.51e-84	249.0	COG3727@1|root,COG3727@2|Bacteria,1VA1Q@1239|Firmicutes,25AZ7@186801|Clostridia,27TYF@186928|unclassified Lachnospiraceae	186801|Clostridia	L	DNA mismatch endonuclease Vsr	vsr	-	-	ko:K07458	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Vsr
HLKFIFDC_00660	1235799.C818_01497	4.8e-183	517.0	COG0270@1|root,COG0270@2|Bacteria,1TSNX@1239|Firmicutes,2490C@186801|Clostridia,27IIV@186928|unclassified Lachnospiraceae	186801|Clostridia	H	C-5 cytosine-specific DNA methylase	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
HLKFIFDC_00661	1341151.ASZU01000010_gene2027	0.000182	47.0	COG0457@1|root,COG0457@2|Bacteria,1UPG8@1239|Firmicutes,4I1WG@91061|Bacilli,27DBK@186824|Thermoactinomycetaceae	1341151.ASZU01000010_gene2027|-	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00662	411463.EUBVEN_00919	0.0	1113.0	COG1961@1|root,COG2265@1|root,COG1961@2|Bacteria,COG2265@2|Bacteria,1TPUG@1239|Firmicutes,25B03@186801|Clostridia,25VPH@186806|Eubacteriaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
HLKFIFDC_00663	1121115.AXVN01000119_gene3272	5.43e-35	119.0	2BJ3C@1|root,32DC9@2|Bacteria,1V88B@1239|Firmicutes,25A9I@186801|Clostridia,3Y20E@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00664	1121115.AXVN01000119_gene3273	4.04e-142	401.0	COG0454@1|root,COG0456@2|Bacteria,1UHW4@1239|Firmicutes,24I24@186801|Clostridia,3Y1FU@572511|Blautia	186801|Clostridia	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00665	1280698.AUJS01000077_gene3303	1.95e-21	84.0	2E3ZC@1|root,32YWA@2|Bacteria,1VHZW@1239|Firmicutes,24SMN@186801|Clostridia,27X8Q@189330|Dorea	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00666	585394.RHOM_13325	0.0	1441.0	COG0457@1|root,COG3903@1|root,COG0457@2|Bacteria,COG3903@2|Bacteria,1TY16@1239|Firmicutes,24A3H@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12
HLKFIFDC_00667	742765.HMPREF9457_01994	1.71e-205	568.0	COG1131@1|root,COG1131@2|Bacteria,1TRJH@1239|Firmicutes,247XQ@186801|Clostridia,27WF2@189330|Dorea	186801|Clostridia	V	COG COG1131 ABC-type multidrug transport system, ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
HLKFIFDC_00668	742765.HMPREF9457_01995	1.76e-153	431.0	2B7SS@1|root,320Z4@2|Bacteria,1V805@1239|Firmicutes,24IU3@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00669	457412.RSAG_01814	1.8e-247	680.0	COG1277@1|root,COG1277@2|Bacteria,1UYRU@1239|Firmicutes,24A07@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
HLKFIFDC_00670	457412.RSAG_01815	5.65e-276	755.0	COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,1TRZX@1239|Firmicutes,249AI@186801|Clostridia,3WIVN@541000|Ruminococcaceae	186801|Clostridia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K20487	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
HLKFIFDC_00671	411469.EUBHAL_02113	2.75e-158	444.0	COG0745@1|root,COG0745@2|Bacteria,1TQ0D@1239|Firmicutes,248WX@186801|Clostridia,25YCG@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K20488	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HLKFIFDC_00672	585394.RHOM_15595	2.97e-72	227.0	COG3505@1|root,COG3505@2|Bacteria,1UVIR@1239|Firmicutes,24E4K@186801|Clostridia	186801|Clostridia	U	COG3505 Type IV secretory pathway, VirD4 components	-	-	-	-	-	-	-	-	-	-	-	-	T4SS-DNA_transf
HLKFIFDC_00673	397291.C804_02972	1.59e-74	225.0	28I1B@1|root,30E9T@2|Bacteria,1V4JB@1239|Firmicutes,24ZUA@186801|Clostridia,27UDH@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Protein of unknown function (DUF3801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3801
HLKFIFDC_00674	1469948.JPNB01000001_gene1410	2e-232	655.0	COG3316@1|root,COG3316@2|Bacteria,1VZPC@1239|Firmicutes,251Y5@186801|Clostridia,36UP2@31979|Clostridiaceae	186801|Clostridia	L	Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
HLKFIFDC_00675	397287.C807_03578	2.01e-46	152.0	COG3436@1|root,COG3436@2|Bacteria,1V7U9@1239|Firmicutes,24K4W@186801|Clostridia,27M9T@186928|unclassified Lachnospiraceae	186801|Clostridia	L	IS66 Orf2 like protein	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
HLKFIFDC_00676	411468.CLOSCI_00172	5.27e-42	143.0	2EBVR@1|root,335V5@2|Bacteria,1VIRS@1239|Firmicutes,24KM5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00677	1195236.CTER_1477	1.17e-134	399.0	28MDA@1|root,2ZAR4@2|Bacteria,1VVTG@1239|Firmicutes,24Z8N@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00678	536227.CcarbDRAFT_1707	9.4e-69	239.0	2FAT1@1|root,34309@2|Bacteria,1VWQB@1239|Firmicutes,251IU@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00679	1378168.N510_00828	2.21e-148	434.0	2DSZA@1|root,33I0U@2|Bacteria,1VMKU@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00680	1378168.N510_00828	1.81e-87	275.0	2DSZA@1|root,33I0U@2|Bacteria,1VMKU@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00681	1504823.CCMM01000012_gene1949	8.12e-08	52.0	28KJ2@1|root,2ZA47@2|Bacteria	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00682	483218.BACPEC_02561	1.07e-204	566.0	COG4974@1|root,COG4974@2|Bacteria,1TR57@1239|Firmicutes,24ACW@186801|Clostridia,26AN9@186813|unclassified Clostridiales	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
HLKFIFDC_00683	1235802.C823_01098	2.05e-142	411.0	COG0517@1|root,COG0517@2|Bacteria,1TQ4J@1239|Firmicutes,24B68@186801|Clostridia,25YB7@186806|Eubacteriaceae	186801|Clostridia	S	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
HLKFIFDC_00684	1280698.AUJS01000077_gene3305	1.31e-267	734.0	COG1668@1|root,COG1668@2|Bacteria,1UY5S@1239|Firmicutes,24DP3@186801|Clostridia,27VKC@189330|Dorea	186801|Clostridia	CP	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
HLKFIFDC_00685	742765.HMPREF9457_01254	2.53e-209	578.0	COG1131@1|root,COG1131@2|Bacteria,1TRJH@1239|Firmicutes,247XQ@186801|Clostridia,27VFX@189330|Dorea	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HLKFIFDC_00686	411461.DORFOR_03049	1.01e-177	496.0	29NVG@1|root,309TJ@2|Bacteria,1V4I1@1239|Firmicutes,24AMS@186801|Clostridia,27VTC@189330|Dorea	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00687	411461.DORFOR_03048	2.67e-113	326.0	COG1595@1|root,COG1595@2|Bacteria,1VBJI@1239|Firmicutes,24NKR@186801|Clostridia,27W9M@189330|Dorea	186801|Clostridia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HLKFIFDC_00688	679192.HMPREF9013_0725	1.14e-25	97.4	2DQMH@1|root,337M4@2|Bacteria,1VIHD@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00689	904296.HMPREF9124_0278	1.12e-224	622.0	COG3943@1|root,COG3943@2|Bacteria,1TPH4@1239|Firmicutes,248NI@186801|Clostridia,2PRPD@265975|Oribacterium	186801|Clostridia	S	Virulence protein RhuM family	-	-	-	-	-	-	-	-	-	-	-	-	Virulence_RhuM
HLKFIFDC_00690	1280698.AUJS01000056_gene1441	1.46e-223	619.0	COG1502@1|root,COG1502@2|Bacteria,1TRJE@1239|Firmicutes,248ZE@186801|Clostridia	186801|Clostridia	I	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
HLKFIFDC_00691	483218.BACPEC_00295	1.93e-51	163.0	2BRTE@1|root,32FAJ@2|Bacteria,1V9NY@1239|Firmicutes,24KVU@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_7
HLKFIFDC_00693	575593.HMPREF0491_01567	2.95e-18	75.9	2ES5P@1|root,33JQG@2|Bacteria,1VN2Z@1239|Firmicutes,24V4V@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00697	1235798.C817_05806	2.63e-223	622.0	2DBVV@1|root,2ZBDB@2|Bacteria,1VI63@1239|Firmicutes,25EZE@186801|Clostridia	186801|Clostridia	S	Transposase zinc-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
HLKFIFDC_00698	742765.HMPREF9457_03068	5.66e-29	103.0	2EI8P@1|root,332BW@2|Bacteria,1VFSF@1239|Firmicutes,25E0X@186801|Clostridia,27XDD@189330|Dorea	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00700	693746.OBV_41840	2.75e-100	304.0	2CAII@1|root,347M4@2|Bacteria,1W0F7@1239|Firmicutes,254G9@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00701	97139.C824_04778	1.51e-08	57.8	COG1475@1|root,COG1475@2|Bacteria,1TR7C@1239|Firmicutes,247TW@186801|Clostridia,36HAM@31979|Clostridiaceae	186801|Clostridia	K	Belongs to the ParB family	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
HLKFIFDC_00702	689781.AUJX01000047_gene2710	1.41e-68	215.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,247R1@186801|Clostridia	186801|Clostridia	D	CobQ CobB MinD ParA nucleotide binding domain protein	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
HLKFIFDC_00703	1235802.C823_01701	1.85e-66	223.0	COG0577@1|root,COG0577@2|Bacteria,1TRAS@1239|Firmicutes,248SQ@186801|Clostridia,25UYY@186806|Eubacteriaceae	186801|Clostridia	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
HLKFIFDC_00704	742765.HMPREF9457_02143	0.0	1342.0	COG0419@1|root,COG1121@1|root,COG0419@2|Bacteria,COG1121@2|Bacteria,1V0RJ@1239|Firmicutes,24EJF@186801|Clostridia	186801|Clostridia	L	ATPase involved in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	AAA_23
HLKFIFDC_00706	742733.HMPREF9469_01135	1.48e-274	754.0	2D2CR@1|root,32TCH@2|Bacteria,1VZ3Z@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00707	1256908.HMPREF0373_02451	1.65e-62	192.0	2C5R4@1|root,2ZRGD@2|Bacteria,1V4WH@1239|Firmicutes,24HA6@186801|Clostridia,25WJJ@186806|Eubacteriaceae	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
HLKFIFDC_00708	1341157.RF007C_12385	9.57e-11	69.7	COG1705@1|root,COG1705@2|Bacteria,1V7JY@1239|Firmicutes,24C0T@186801|Clostridia	186801|Clostridia	NU	mannosyl-glycoprotein	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_3,Glucosaminidase
HLKFIFDC_00711	888743.HMPREF9141_2430	5.46e-75	241.0	COG4974@1|root,COG4974@2|Bacteria,4NHEY@976|Bacteroidetes,2FM00@200643|Bacteroidia	976|Bacteroidetes	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
HLKFIFDC_00715	476272.RUMHYD_00002	3.52e-19	100.0	29QQP@1|root,30BQG@2|Bacteria,1W45N@1239|Firmicutes,2566N@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00717	1235798.C817_02568	4.65e-194	578.0	COG2885@1|root,COG4926@1|root,COG2885@2|Bacteria,COG4926@2|Bacteria,1UZUG@1239|Firmicutes,25B8B@186801|Clostridia	186801|Clostridia	M	Prophage endopeptidase tail	-	-	-	-	-	-	-	-	-	-	-	-	Prophage_tail
HLKFIFDC_00718	1235798.C817_04593	1.97e-76	237.0	COG4722@1|root,COG4722@2|Bacteria,1V6VK@1239|Firmicutes,24SWE@186801|Clostridia	186801|Clostridia	S	phage tail	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00719	1235798.C817_04592	2.1e-156	490.0	COG5280@1|root,COG5412@1|root,COG5280@2|Bacteria,COG5412@2|Bacteria,1V0FN@1239|Firmicutes,25B5M@186801|Clostridia	186801|Clostridia	D	Phage-related minor tail protein	-	-	-	-	-	-	-	-	-	-	-	-	PhageMin_Tail
HLKFIFDC_00721	1235798.C817_04591	6.77e-49	160.0	2DZ02@1|root,34BYF@2|Bacteria,1W0WX@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00722	33035.JPJF01000039_gene278	4.25e-61	196.0	29WCU@1|root,30HYH@2|Bacteria,1TUNP@1239|Firmicutes,25JIB@186801|Clostridia,3Y232@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00723	1235798.C817_04589	1.15e-75	229.0	29VFV@1|root,30GX6@2|Bacteria,1UGTY@1239|Firmicutes,24QD1@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00724	1235798.C817_04588	3.74e-36	125.0	2CIFU@1|root,3478B@2|Bacteria,1VZ1H@1239|Firmicutes,24RZN@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00725	33035.JPJF01000039_gene275	2.93e-38	131.0	2FGWY@1|root,348S8@2|Bacteria,1VYZY@1239|Firmicutes,24UBY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00726	1235798.C817_04586	8.43e-22	88.6	2EAYR@1|root,334ZP@2|Bacteria,1VHJ5@1239|Firmicutes,24W8P@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00727	1235798.C817_04585	6.68e-131	393.0	COG4653@1|root,COG4653@2|Bacteria,1UZMH@1239|Firmicutes,24AT9@186801|Clostridia	186801|Clostridia	G	phage major capsid protein, HK97 family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_capsid
HLKFIFDC_00728	1232446.BAIE02000002_gene825	4.04e-82	248.0	COG3740@1|root,COG3740@2|Bacteria,1V1UF@1239|Firmicutes,24HKG@186801|Clostridia	186801|Clostridia	S	Phage prohead protease, HK97 family	-	-	-	ko:K06904	-	-	-	-	ko00000	-	-	-	Peptidase_S78
HLKFIFDC_00729	1232446.BAIE02000002_gene824	6.16e-183	520.0	COG4695@1|root,COG4695@2|Bacteria,1TPB9@1239|Firmicutes,24BAK@186801|Clostridia	186801|Clostridia	S	Phage portal protein, HK97 family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_portal
HLKFIFDC_00730	1235798.C817_04582	1.88e-230	655.0	COG4626@1|root,COG4626@2|Bacteria,1TPU1@1239|Firmicutes,24DKT@186801|Clostridia	186801|Clostridia	S	Phage Terminase	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_1
HLKFIFDC_00732	908340.HMPREF9406_2583	1.22e-52	166.0	COG1403@1|root,COG1403@2|Bacteria,1VERX@1239|Firmicutes,24PII@186801|Clostridia	186801|Clostridia	V	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH
HLKFIFDC_00734	1211817.CCAT010000008_gene935	4.72e-62	197.0	COG0582@1|root,COG0582@2|Bacteria,1V2RX@1239|Firmicutes,24DD0@186801|Clostridia,36J61@31979|Clostridiaceae	186801|Clostridia	L	integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
HLKFIFDC_00737	397290.C810_01505	1.45e-34	120.0	2FF4R@1|root,326J1@2|Bacteria,1UFPG@1239|Firmicutes,25PPK@186801|Clostridia,27T5V@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00740	411469.EUBHAL_00354	5.67e-172	488.0	COG3081@1|root,COG3081@2|Bacteria,1TSR5@1239|Firmicutes,25CG3@186801|Clostridia,25WHK@186806|Eubacteriaceae	186801|Clostridia	S	37-kD nucleoid-associated bacterial protein	-	-	-	-	-	-	-	-	-	-	-	-	NA37
HLKFIFDC_00741	642492.Clole_0798	6.48e-19	91.3	COG3935@1|root,COG3935@2|Bacteria,1V6IW@1239|Firmicutes,24FSU@186801|Clostridia	186801|Clostridia	L	Domain of unknown function (DUF4373)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4373,DnaB_2
HLKFIFDC_00744	1232453.BAIF02000028_gene2716	1.61e-70	237.0	COG1475@1|root,COG1475@2|Bacteria,1TPT0@1239|Firmicutes,25D1Y@186801|Clostridia	186801|Clostridia	K	ParB-like nuclease domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3850,ParBc
HLKFIFDC_00745	411468.CLOSCI_01475	7.45e-76	238.0	COG1192@1|root,COG1192@2|Bacteria,1TRXR@1239|Firmicutes,24E98@186801|Clostridia,220RU@1506553|Lachnoclostridium	186801|Clostridia	D	Cellulose biosynthesis protein BcsQ	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
HLKFIFDC_00750	1449343.JQLQ01000002_gene686	4.87e-12	66.2	2E5YK@1|root,330N9@2|Bacteria,1VHAM@1239|Firmicutes,4HR0A@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00756	1151292.QEW_4373	4.31e-13	63.9	2EJ02@1|root,33CR7@2|Bacteria,1VPEQ@1239|Firmicutes,24WQH@186801|Clostridia	186801|Clostridia	S	Arc-like DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Arc
HLKFIFDC_00759	411470.RUMGNA_00191	3.58e-40	137.0	COG1396@1|root,COG1396@2|Bacteria,1VEU8@1239|Firmicutes,24QN0@186801|Clostridia	186801|Clostridia	K	DNA-binding helix-turn-helix protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
HLKFIFDC_00761	411461.DORFOR_01128	4.87e-15	69.3	2FEHX@1|root,346HE@2|Bacteria,1W0NE@1239|Firmicutes,24WRC@186801|Clostridia,27X6I@189330|Dorea	186801|Clostridia	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26,HTH_3
HLKFIFDC_00763	536233.CLO_1870	7.89e-110	334.0	COG1396@1|root,COG2856@1|root,COG1396@2|Bacteria,COG2856@2|Bacteria,1TSEK@1239|Firmicutes,249G9@186801|Clostridia,36FH5@31979|Clostridiaceae	186801|Clostridia	K	IrrE N-terminal-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,Peptidase_M78
HLKFIFDC_00764	1408823.AXUS01000009_gene1981	1.93e-20	92.4	COG3064@1|root,COG3064@2|Bacteria,1VASR@1239|Firmicutes,24IM3@186801|Clostridia,25TC4@186804|Peptostreptococcaceae	186801|Clostridia	M	Host cell surface-exposed lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_Ltp
HLKFIFDC_00765	1304866.K413DRAFT_0813	2.35e-12	62.4	2ER7G@1|root,33IT2@2|Bacteria,1VPWQ@1239|Firmicutes,24RB1@186801|Clostridia,36TVU@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00766	411902.CLOBOL_02558	1.08e-155	452.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,25C3T@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
HLKFIFDC_00767	411469.EUBHAL_02103	0.0	881.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia,25UTK@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
HLKFIFDC_00768	411469.EUBHAL_02102	7.23e-124	352.0	COG0622@1|root,COG0622@2|Bacteria,1VA0U@1239|Firmicutes,24MMK@186801|Clostridia,25WR2@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	yfcE1	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
HLKFIFDC_00769	411469.EUBHAL_02101	1.75e-131	374.0	COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,249GK@186801|Clostridia,25V8Q@186806|Eubacteriaceae	186801|Clostridia	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
HLKFIFDC_00770	411469.EUBHAL_02100	2.08e-289	789.0	COG0116@1|root,COG0116@2|Bacteria,1TP0X@1239|Firmicutes,248MA@186801|Clostridia,25V1E@186806|Eubacteriaceae	186801|Clostridia	L	Belongs to the methyltransferase superfamily	ypsC	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
HLKFIFDC_00771	411469.EUBHAL_02099	6.56e-80	238.0	COG0607@1|root,COG0607@2|Bacteria,1VGXK@1239|Firmicutes,24R46@186801|Clostridia,25XUH@186806|Eubacteriaceae	186801|Clostridia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
HLKFIFDC_00772	411469.EUBHAL_02851	9.45e-300	817.0	COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,247QC@186801|Clostridia,25URF@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
HLKFIFDC_00774	411469.EUBHAL_02168	0.0	1355.0	COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,247WH@186801|Clostridia,25V82@186806|Eubacteriaceae	186801|Clostridia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
HLKFIFDC_00775	411469.EUBHAL_02167	2.83e-264	722.0	COG0115@1|root,COG0115@2|Bacteria,1TQQI@1239|Firmicutes,2480D@186801|Clostridia,25V2T@186806|Eubacteriaceae	186801|Clostridia	E	Branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42,4.1.3.38	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R05553,R10991	RC00006,RC00036,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
HLKFIFDC_00776	411469.EUBHAL_02166	0.0	870.0	COG5492@1|root,COG5492@2|Bacteria,1V4A5@1239|Firmicutes	1239|Firmicutes	N	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
HLKFIFDC_00777	411469.EUBHAL_02165	6.42e-154	432.0	COG2755@1|root,COG2755@2|Bacteria,1VEMX@1239|Firmicutes,24R36@186801|Clostridia	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_lke
HLKFIFDC_00778	411469.EUBHAL_02164	2.73e-206	570.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,247ST@186801|Clostridia,25YT5@186806|Eubacteriaceae	186801|Clostridia	S	Uncharacterised protein, DegV family COG1307	-	-	-	-	-	-	-	-	-	-	-	-	DegV
HLKFIFDC_00779	411469.EUBHAL_02163	0.0	1141.0	COG0849@1|root,COG0849@2|Bacteria,1TQMU@1239|Firmicutes,24840@186801|Clostridia,25UW8@186806|Eubacteriaceae	186801|Clostridia	D	Diol dehydratase reactivase ATPase-like domain	dhaB4	-	-	-	-	-	-	-	-	-	-	-	DDR
HLKFIFDC_00780	411469.EUBHAL_02162	1.74e-222	613.0	2BHVM@1|root,32BZG@2|Bacteria,1UK71@1239|Firmicutes,25FNR@186801|Clostridia,25Z6A@186806|Eubacteriaceae	411469.EUBHAL_02162|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00781	411469.EUBHAL_02161	0.0	1205.0	2DGTK@1|root,2ZX8T@2|Bacteria,1V4M1@1239|Firmicutes,24HP5@186801|Clostridia,25ZQH@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00782	411469.EUBHAL_02160	0.0	1324.0	2DGTK@1|root,2ZX8T@2|Bacteria,1V4M1@1239|Firmicutes,24HP5@186801|Clostridia,25ZQH@186806|Eubacteriaceae	1239|Firmicutes	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00783	411469.EUBHAL_02159	1.48e-226	624.0	COG0463@1|root,COG0463@2|Bacteria,1UI8D@1239|Firmicutes,247P4@186801|Clostridia,25V3J@186806|Eubacteriaceae	186801|Clostridia	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HLKFIFDC_00784	411469.EUBHAL_02157	7.21e-236	648.0	COG0523@1|root,COG3689@1|root,COG0523@2|Bacteria,COG3689@2|Bacteria,1TS8P@1239|Firmicutes,248DY@186801|Clostridia,25V7X@186806|Eubacteriaceae	186801|Clostridia	S	CobW/HypB/UreG, nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cobW
HLKFIFDC_00785	411469.EUBHAL_02156	2.71e-218	609.0	COG0523@1|root,COG0523@2|Bacteria,1TPCG@1239|Firmicutes,248XD@186801|Clostridia,25VUJ@186806|Eubacteriaceae	186801|Clostridia	S	CobW P47K family protein	cobW	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
HLKFIFDC_00786	411469.EUBHAL_02154	4.46e-42	137.0	2EHCX@1|root,31TEV@2|Bacteria,1TUTI@1239|Firmicutes,258C7@186801|Clostridia,25XS1@186806|Eubacteriaceae	186801|Clostridia	S	Spore coat associated protein JA (CotJA)	-	-	-	-	-	-	-	-	-	-	-	-	CotJA
HLKFIFDC_00787	411469.EUBHAL_02153	3.17e-59	184.0	2E34J@1|root,32Y4N@2|Bacteria,1VESM@1239|Firmicutes,24QZX@186801|Clostridia,25XSD@186806|Eubacteriaceae	186801|Clostridia	S	CotJB protein	cotJB	-	-	ko:K06333	-	-	-	-	ko00000	-	-	-	CotJB
HLKFIFDC_00788	411469.EUBHAL_02152	5.9e-46	147.0	COG3546@1|root,COG3546@2|Bacteria,1TQVQ@1239|Firmicutes,247YJ@186801|Clostridia,25X7P@186806|Eubacteriaceae	186801|Clostridia	P	Manganese containing catalase	cotJC	-	-	ko:K06334	-	-	-	-	ko00000	-	-	-	Mn_catalase
HLKFIFDC_00789	411469.EUBHAL_02150	3.01e-189	526.0	COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,247WV@186801|Clostridia,25V3Q@186806|Eubacteriaceae	186801|Clostridia	M	Belongs to the nlpA lipoprotein family	metQ	-	-	ko:K02073	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	Lipoprotein_9
HLKFIFDC_00790	411469.EUBHAL_02822	5.78e-139	394.0	COG2011@1|root,COG2011@2|Bacteria,1TRSY@1239|Firmicutes,24AZ9@186801|Clostridia,25UWJ@186806|Eubacteriaceae	186801|Clostridia	P	ABC transporter, permease protein	metI	-	-	ko:K02072	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	BPD_transp_1
HLKFIFDC_00791	411469.EUBHAL_02823	2.62e-240	661.0	COG1135@1|root,COG1135@2|Bacteria,1TPPN@1239|Firmicutes,248PZ@186801|Clostridia,25VBJ@186806|Eubacteriaceae	186801|Clostridia	P	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system	metN	-	-	ko:K02071	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	ABC_tran,NIL
HLKFIFDC_00792	1122217.KB899568_gene830	4.94e-14	68.6	2DQGJ@1|root,336QW@2|Bacteria,1VJEV@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00793	1232447.BAHW02000027_gene1806	2.04e-173	486.0	COG3716@1|root,COG3716@2|Bacteria,1UNST@1239|Firmicutes,25C3B@186801|Clostridia	186801|Clostridia	G	system, mannose fructose sorbose family IID component	-	-	-	-	-	-	-	-	-	-	-	-	EIID-AGA
HLKFIFDC_00794	1232447.BAHW02000027_gene1807	2.03e-152	433.0	COG3715@1|root,COG3715@2|Bacteria,1U8TN@1239|Firmicutes,24AR4@186801|Clostridia	186801|Clostridia	G	PTS system sorbose-specific iic component	-	-	-	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.6.1	-	-	EII-Sor
HLKFIFDC_00795	1232447.BAHW02000027_gene1808	1.78e-102	298.0	COG3444@1|root,COG3444@2|Bacteria,1UZRR@1239|Firmicutes,24G18@186801|Clostridia	186801|Clostridia	G	system sorbose subfamily IIB component	-	-	2.7.1.191	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1	-	-	PTSIIB_sorb
HLKFIFDC_00796	1232447.BAHW02000027_gene1809	1.63e-60	190.0	COG2893@1|root,COG2893@2|Bacteria,1VBC1@1239|Firmicutes,24PAX@186801|Clostridia	186801|Clostridia	G	PTS system fructose IIA component	-	-	-	ko:K02744	ko00052,ko02060,map00052,map02060	M00277,M00287	R08366,R08367	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1.4,4.A.6.1.5	-	-	EIIA-man
HLKFIFDC_00797	1232447.BAHW02000027_gene1810	4.01e-169	489.0	COG1653@1|root,COG1653@2|Bacteria,1TPX9@1239|Firmicutes,24DGD@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
HLKFIFDC_00798	1232447.BAHW02000027_gene1811	7.36e-98	291.0	COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,24FZX@186801|Clostridia,269AP@186813|unclassified Clostridiales	186801|Clostridia	T	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
HLKFIFDC_00799	1232447.BAHW02000027_gene1812	1.06e-135	403.0	COG4585@1|root,COG4585@2|Bacteria,1TQI3@1239|Firmicutes,249R9@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,dCache_1
HLKFIFDC_00800	1232447.BAHW02000027_gene1813	1.83e-121	359.0	COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,249ZI@186801|Clostridia	186801|Clostridia	G	COG COG1879 ABC-type sugar transport system, periplasmic component	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
HLKFIFDC_00802	411469.EUBHAL_02825	7.9e-293	797.0	COG0727@1|root,COG0727@2|Bacteria,1TSB6@1239|Firmicutes,24AQ9@186801|Clostridia,25WKM@186806|Eubacteriaceae	186801|Clostridia	S	Cytoplasmic, score 8.87	fliU	-	-	ko:K18475	-	-	-	-	ko00000,ko01000,ko02035	-	-	-	-
HLKFIFDC_00803	411469.EUBHAL_02827	8.18e-215	594.0	COG1961@1|root,COG1961@2|Bacteria,1TPBH@1239|Firmicutes,248J7@186801|Clostridia,25VYY@186806|Eubacteriaceae	186801|Clostridia	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
HLKFIFDC_00804	411469.EUBHAL_02828	1.78e-106	306.0	COG3546@1|root,COG3546@2|Bacteria,1TQVQ@1239|Firmicutes,247YJ@186801|Clostridia,25WC5@186806|Eubacteriaceae	186801|Clostridia	P	Psort location Cytoplasmic, score	cotJC	-	-	ko:K06334	-	-	-	-	ko00000	-	-	-	Mn_catalase
HLKFIFDC_00805	411459.RUMOBE_00398	1.44e-307	858.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,Response_reg
HLKFIFDC_00806	411469.EUBHAL_02831	3.02e-144	407.0	2ECC3@1|root,336AG@2|Bacteria,1UK74@1239|Firmicutes	1239|Firmicutes	S	Spy0128-like isopeptide containing domain	-	-	-	-	-	-	-	-	-	-	-	-	FctA
HLKFIFDC_00807	411469.EUBHAL_02832	1.57e-184	513.0	COG4509@1|root,COG4509@2|Bacteria,1V2EF@1239|Firmicutes,24CIH@186801|Clostridia,25W42@186806|Eubacteriaceae	186801|Clostridia	S	sortase, SrtB family	-	-	3.4.22.70	ko:K08600	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
HLKFIFDC_00808	411469.EUBHAL_02833	2.88e-224	619.0	29C84@1|root,2ZZ6N@2|Bacteria,1V3W7@1239|Firmicutes,24IZR@186801|Clostridia	186801|Clostridia	S	Pilin isopeptide linkage domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FctA
HLKFIFDC_00809	411469.EUBHAL_02834	4.28e-125	356.0	COG0681@1|root,COG0681@2|Bacteria,1V954@1239|Firmicutes,24JWF@186801|Clostridia	186801|Clostridia	U	Belongs to the peptidase S26 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S26
HLKFIFDC_00810	411469.EUBHAL_02835	1.9e-89	263.0	2DRVZ@1|root,33DC6@2|Bacteria,1VPFD@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00811	411469.EUBHAL_02836	3.48e-305	853.0	2DWUM@1|root,341YW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00812	411469.EUBHAL_02839	4.89e-203	562.0	COG4974@1|root,COG4974@2|Bacteria,1TY7M@1239|Firmicutes,24BN9@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
HLKFIFDC_00813	411469.EUBHAL_02840	6.69e-238	654.0	COG1712@1|root,COG1712@2|Bacteria,1TQ4R@1239|Firmicutes,2499V@186801|Clostridia,25ZUP@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate	ddh	-	1.4.1.16	ko:K03340	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	M00526	R02755	RC00006	ko00000,ko00001,ko00002,ko01000	-	-	-	DAPDH_C,DapB_N
HLKFIFDC_00814	411469.EUBHAL_02842	7.78e-201	556.0	COG1578@1|root,COG1578@2|Bacteria,1UURD@1239|Firmicutes,2492C@186801|Clostridia,25WJF@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function DUF89	-	-	-	ko:K09116	-	-	-	-	ko00000	-	-	-	DUF89
HLKFIFDC_00815	411469.EUBHAL_02843	6.7e-124	352.0	COG4917@1|root,COG4917@2|Bacteria,1VAYC@1239|Firmicutes,24F8T@186801|Clostridia,25W1X@186806|Eubacteriaceae	186801|Clostridia	E	ethanolamine utilization protein EutP	eutP	-	-	ko:K04029	-	-	-	-	ko00000	-	-	-	PduV-EutP
HLKFIFDC_00816	411469.EUBHAL_02844	1.45e-85	252.0	COG4810@1|root,COG4810@2|Bacteria,1V452@1239|Firmicutes,25DMT@186801|Clostridia,25ZJH@186806|Eubacteriaceae	186801|Clostridia	E	BMC	-	-	-	ko:K04031	-	-	-	-	ko00000	-	-	-	BMC
HLKFIFDC_00817	411469.EUBHAL_02845	4.07e-212	585.0	COG0685@1|root,COG0685@2|Bacteria,1TQFE@1239|Firmicutes,247ZK@186801|Clostridia,25VP5@186806|Eubacteriaceae	186801|Clostridia	C	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
HLKFIFDC_00818	1232453.BAIF02000127_gene128	2.71e-47	152.0	arCOG05874@1|root,2ZJ01@2|Bacteria,1VARV@1239|Firmicutes,24NY6@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00820	411469.EUBHAL_01265	3.33e-215	595.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,25VK1@186806|Eubacteriaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
HLKFIFDC_00821	411469.EUBHAL_01266	7.58e-184	513.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,25WAU@186806|Eubacteriaceae	186801|Clostridia	P	ABC transporter, permease protein	-	-	-	ko:K15586	ko02010,map02010	M00440	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
HLKFIFDC_00822	411469.EUBHAL_01267	0.0	1040.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,248A3@186801|Clostridia,25VZ3@186806|Eubacteriaceae	186801|Clostridia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
HLKFIFDC_00823	411469.EUBHAL_01268	7.14e-184	511.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,25VM8@186806|Eubacteriaceae	186801|Clostridia	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
HLKFIFDC_00824	411469.EUBHAL_01269	8.68e-229	630.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,25VRJ@186806|Eubacteriaceae	186801|Clostridia	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
HLKFIFDC_00825	411469.EUBHAL_01270	4.23e-293	799.0	COG1887@1|root,COG1887@2|Bacteria,1TSTN@1239|Firmicutes,24AA5@186801|Clostridia,25X6Z@186806|Eubacteriaceae	186801|Clostridia	M	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase	-	-	2.7.8.14,2.7.8.47	ko:K18704	-	-	R11614,R11621	-	ko00000,ko01000	-	-	-	Glycos_transf_2,Glyphos_transf
HLKFIFDC_00826	411469.EUBHAL_01271	3.69e-153	432.0	2AY35@1|root,31Q4Y@2|Bacteria,1U59V@1239|Firmicutes,25P9A@186801|Clostridia,25ZAU@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00828	411469.EUBHAL_01273	8.27e-223	615.0	COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,247W9@186801|Clostridia,25VDT@186806|Eubacteriaceae	186801|Clostridia	C	phosphate acetyltransferase	pta	-	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
HLKFIFDC_00829	411469.EUBHAL_01274	8.44e-262	717.0	COG0371@1|root,COG0371@2|Bacteria,1TQFU@1239|Firmicutes,248KH@186801|Clostridia,25UX8@186806|Eubacteriaceae	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	dhaD	-	1.1.1.6	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	-	R01034,R10715,R10717	RC00029,RC00117,RC00670	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
HLKFIFDC_00830	411469.EUBHAL_01275	0.0	2037.0	COG0419@1|root,COG0419@2|Bacteria,1TPCS@1239|Firmicutes,24A22@186801|Clostridia,25V5I@186806|Eubacteriaceae	186801|Clostridia	L	Putative exonuclease SbcCD, C subunit	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,AAA_29,SbcCD_C
HLKFIFDC_00831	411469.EUBHAL_01276	8.63e-295	803.0	COG0420@1|root,COG0420@2|Bacteria,1TQY6@1239|Firmicutes,248VE@186801|Clostridia,25VTM@186806|Eubacteriaceae	186801|Clostridia	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,SbcD_C
HLKFIFDC_00832	411469.EUBHAL_01278	1.77e-212	588.0	COG0697@1|root,COG0697@2|Bacteria,1TRH8@1239|Firmicutes,24B85@186801|Clostridia,25VJC@186806|Eubacteriaceae	186801|Clostridia	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HLKFIFDC_00833	573063.Metin_0897	1.12e-27	109.0	COG1437@1|root,arCOG01723@2157|Archaea,2XYQS@28890|Euryarchaeota,23R09@183939|Methanococci	183939|Methanococci	F	PFAM Adenylate cyclase	-	GO:0003674,GO:0003824,GO:0004016,GO:0009975,GO:0016829,GO:0016849	4.6.1.1	ko:K05873	ko00230,map00230	-	R00089,R00434	RC00295	ko00000,ko00001,ko01000	-	-	-	CYTH
HLKFIFDC_00835	411469.EUBHAL_01280	5.45e-171	477.0	COG3363@1|root,COG3363@2|Bacteria,1TRA7@1239|Firmicutes,249ZW@186801|Clostridia,25V2N@186806|Eubacteriaceae	186801|Clostridia	F	IMP cyclohydrolase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	IMP_cyclohyd
HLKFIFDC_00836	411469.EUBHAL_01281	6.02e-291	793.0	COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,24AB8@186801|Clostridia,25VKE@186806|Eubacteriaceae	186801|Clostridia	F	COG0138 AICAR transformylase IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful)	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas
HLKFIFDC_00837	411469.EUBHAL_01282	2.87e-43	140.0	2EIFH@1|root,33C6V@2|Bacteria,1VNPG@1239|Firmicutes,24V5E@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00838	411469.EUBHAL_01283	3.2e-143	404.0	COG0118@1|root,COG0118@2|Bacteria,1TQT0@1239|Firmicutes,248SH@186801|Clostridia,25V5D@186806|Eubacteriaceae	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
HLKFIFDC_00839	411469.EUBHAL_01284	1.68e-177	494.0	COG0107@1|root,COG0107@2|Bacteria,1TP0W@1239|Firmicutes,24900@186801|Clostridia,25UY6@186806|Eubacteriaceae	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
HLKFIFDC_00840	411469.EUBHAL_01286	3.37e-222	613.0	COG1619@1|root,COG1619@2|Bacteria,1TRBB@1239|Firmicutes,24ABA@186801|Clostridia,25W50@186806|Eubacteriaceae	186801|Clostridia	V	LD-carboxypeptidase	-	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
HLKFIFDC_00841	411469.EUBHAL_01287	9.42e-28	100.0	COG0828@1|root,COG0828@2|Bacteria,1VEHU@1239|Firmicutes,24QP9@186801|Clostridia,25XHW@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
HLKFIFDC_00842	411469.EUBHAL_01288	8.62e-233	641.0	COG2376@1|root,COG2376@2|Bacteria,1TP92@1239|Firmicutes,2488D@186801|Clostridia,25VWW@186806|Eubacteriaceae	186801|Clostridia	H	Dihydroxyacetone kinase, DhaK subunit	dhaK	-	2.7.1.121	ko:K05878	ko00561,ko01100,map00561,map01100	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000	-	-	-	Dak1
HLKFIFDC_00843	411469.EUBHAL_01289	1.96e-137	390.0	COG1461@1|root,COG1461@2|Bacteria,1V4FH@1239|Firmicutes,24FUX@186801|Clostridia,25VQY@186806|Eubacteriaceae	186801|Clostridia	S	Dihydroxyacetone kinase, L subunit	dhaL	-	2.7.1.121	ko:K05879	ko00561,ko01100,map00561,map01100	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000	-	-	-	Dak2
HLKFIFDC_00844	411469.EUBHAL_01290	5.47e-76	228.0	COG3412@1|root,COG3412@2|Bacteria,1VF32@1239|Firmicutes,24N8B@186801|Clostridia,25WYV@186806|Eubacteriaceae	186801|Clostridia	H	PTS system fructose IIA component	-	-	2.7.1.121	ko:K05881	ko00561,map00561	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000,ko02000	-	-	-	EIIA-man
HLKFIFDC_00845	1235802.C823_05160	4.99e-10	70.9	COG3210@1|root,COG3210@2|Bacteria,1V6R1@1239|Firmicutes,24RZ9@186801|Clostridia,25X8N@186806|Eubacteriaceae	186801|Clostridia	U	Leucine rich repeats (6 copies)	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
HLKFIFDC_00847	411469.EUBHAL_01292	5.18e-280	767.0	COG0561@1|root,COG0561@2|Bacteria,1TR3N@1239|Firmicutes,24ACD@186801|Clostridia,25W4V@186806|Eubacteriaceae	186801|Clostridia	S	sporulation protein	yqfD	-	-	ko:K06438	-	-	-	-	ko00000	-	-	-	YqfD
HLKFIFDC_00848	411469.EUBHAL_01293	2.52e-237	653.0	COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,247ZJ@186801|Clostridia,25V1W@186806|Eubacteriaceae	186801|Clostridia	T	phosphate starvation-inducible protein	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
HLKFIFDC_00849	411469.EUBHAL_01294	1.65e-118	338.0	COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,24MQZ@186801|Clostridia,25WKQ@186806|Eubacteriaceae	186801|Clostridia	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	3.5.4.5	ko:K01489,ko:K07042	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000,ko03009	-	-	-	UPF0054
HLKFIFDC_00850	411469.EUBHAL_01295	0.0	1030.0	COG2081@1|root,COG2081@2|Bacteria,1TR7U@1239|Firmicutes,2497W@186801|Clostridia,25VNR@186806|Eubacteriaceae	186801|Clostridia	S	Flavoprotein family	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
HLKFIFDC_00851	411469.EUBHAL_01296	0.0	1109.0	COG2509@1|root,COG2509@2|Bacteria,1TPBW@1239|Firmicutes,247TR@186801|Clostridia,25UTR@186806|Eubacteriaceae	186801|Clostridia	S	'oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	HI0933_like,NAD_binding_8,Pyr_redox_2
HLKFIFDC_00852	411469.EUBHAL_01297	3.8e-43	140.0	COG4224@1|root,COG4224@2|Bacteria,1UQR0@1239|Firmicutes,258HB@186801|Clostridia,25XM2@186806|Eubacteriaceae	186801|Clostridia	S	Bacterial protein of unknown function (DUF896)	-	-	-	-	-	-	-	-	-	-	-	-	DUF896
HLKFIFDC_00853	411469.EUBHAL_01298	2.71e-130	370.0	COG0212@1|root,COG0212@2|Bacteria,1VA91@1239|Firmicutes,24N7H@186801|Clostridia,25WW2@186806|Eubacteriaceae	186801|Clostridia	H	5-formyltetrahydrofolate cyclo-ligase	fthC	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
HLKFIFDC_00854	411469.EUBHAL_01299	4.54e-144	406.0	COG1309@1|root,COG1309@2|Bacteria,1V3ZS@1239|Firmicutes,24H9U@186801|Clostridia,25WHX@186806|Eubacteriaceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HLKFIFDC_00855	411469.EUBHAL_01300	0.0	1311.0	COG1033@1|root,COG1033@2|Bacteria,1VSWA@1239|Firmicutes,247R6@186801|Clostridia,25UQF@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
HLKFIFDC_00856	411469.EUBHAL_01301	5.51e-286	816.0	COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,24A8K@186801|Clostridia,25VC5@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cellwall, score	-	-	-	ko:K01421	-	-	-	-	ko00000	-	-	-	-
HLKFIFDC_00857	411469.EUBHAL_01302	1.15e-101	295.0	COG0779@1|root,COG0779@2|Bacteria,1V6KT@1239|Firmicutes,24N1G@186801|Clostridia,25WA4@186806|Eubacteriaceae	186801|Clostridia	J	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
HLKFIFDC_00858	411469.EUBHAL_01303	5.78e-271	744.0	COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,247W8@186801|Clostridia,25URA@186806|Eubacteriaceae	186801|Clostridia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
HLKFIFDC_00859	411469.EUBHAL_01304	2.01e-57	178.0	COG2740@1|root,COG2740@2|Bacteria,1VEJS@1239|Firmicutes,24QSJ@186801|Clostridia,25X7A@186806|Eubacteriaceae	186801|Clostridia	K	nucleic-acid-binding protein implicated in transcription termination	ylxR	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
HLKFIFDC_00860	411469.EUBHAL_01305	8.74e-64	195.0	COG1358@1|root,COG1358@2|Bacteria,1VEYG@1239|Firmicutes,24QP3@186801|Clostridia,25XF8@186806|Eubacteriaceae	186801|Clostridia	J	ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_L7Ae
HLKFIFDC_00861	411469.EUBHAL_01306	0.0	1337.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia,25V39@186806|Eubacteriaceae	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
HLKFIFDC_00862	411469.EUBHAL_01307	3.41e-80	238.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,24MPB@186801|Clostridia,25WPN@186806|Eubacteriaceae	186801|Clostridia	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
HLKFIFDC_00863	411469.EUBHAL_01308	2.12e-254	697.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,248R3@186801|Clostridia,25VIX@186806|Eubacteriaceae	186801|Clostridia	J	DHHA1 domain protein	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
HLKFIFDC_00864	411469.EUBHAL_01309	1.63e-242	667.0	COG0130@1|root,COG0130@2|Bacteria,1TP9Y@1239|Firmicutes,24B46@186801|Clostridia,25VJZ@186806|Eubacteriaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
HLKFIFDC_00865	411469.EUBHAL_01310	5.18e-221	609.0	COG0196@1|root,COG0196@2|Bacteria,1TPKS@1239|Firmicutes,2484A@186801|Clostridia,25VWI@186806|Eubacteriaceae	186801|Clostridia	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
HLKFIFDC_00866	411469.EUBHAL_01311	3.59e-147	414.0	COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249Z9@186801|Clostridia,25W68@186806|Eubacteriaceae	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin2
HLKFIFDC_00867	411469.EUBHAL_02195	3.85e-159	451.0	28JN4@1|root,2Z9EJ@2|Bacteria,1TRQI@1239|Firmicutes,24E4X@186801|Clostridia,25WQJ@186806|Eubacteriaceae	186801|Clostridia	S	Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_31
HLKFIFDC_00868	411469.EUBHAL_02718	1.02e-34	122.0	2DQDG@1|root,3363Y@2|Bacteria,1VFB3@1239|Firmicutes,24S14@186801|Clostridia,25YVI@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00870	742735.HMPREF9467_00122	1.66e-74	233.0	COG3039@1|root,COG3039@2|Bacteria,1TPFS@1239|Firmicutes,249JM@186801|Clostridia	186801|Clostridia	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
HLKFIFDC_00871	180332.JTGN01000021_gene1465	6.44e-157	450.0	COG3039@1|root,COG3039@2|Bacteria,1TPFS@1239|Firmicutes,249JM@186801|Clostridia	186801|Clostridia	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
HLKFIFDC_00872	411469.EUBHAL_01312	8.72e-174	484.0	COG0655@1|root,COG0655@2|Bacteria,1TT84@1239|Firmicutes,248W0@186801|Clostridia,25WIS@186806|Eubacteriaceae	186801|Clostridia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
HLKFIFDC_00873	411469.EUBHAL_01313	1.06e-183	511.0	COG4816@1|root,COG4816@2|Bacteria,1TTAA@1239|Firmicutes,2498G@186801|Clostridia,25UYN@186806|Eubacteriaceae	186801|Clostridia	E	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
HLKFIFDC_00874	411469.EUBHAL_01314	0.0	2342.0	COG1038@1|root,COG1038@2|Bacteria,1UHP9@1239|Firmicutes,25E5B@186801|Clostridia,25ZK1@186806|Eubacteriaceae	186801|Clostridia	C	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second	pyc	-	6.4.1.1	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS18410	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA
HLKFIFDC_00875	411469.EUBHAL_01315	6.5e-306	834.0	COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,248HT@186801|Clostridia,25XFF@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
HLKFIFDC_00876	411469.EUBHAL_01316	0.0	904.0	COG1362@1|root,COG1362@2|Bacteria,1TP6G@1239|Firmicutes,2486Y@186801|Clostridia,25V89@186806|Eubacteriaceae	186801|Clostridia	E	M18 family aminopeptidase	apeA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M18
HLKFIFDC_00877	411469.EUBHAL_01317	7.42e-64	196.0	2DQ36@1|root,334JH@2|Bacteria,1VF6I@1239|Firmicutes,24TEH@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
HLKFIFDC_00878	411469.EUBHAL_01318	0.0	1676.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia,25UTU@186806|Eubacteriaceae	186801|Clostridia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
HLKFIFDC_00879	411469.EUBHAL_01319	1.63e-145	410.0	COG0237@1|root,COG0237@2|Bacteria,1V6FS@1239|Firmicutes,24GFQ@186801|Clostridia,25WR0@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
HLKFIFDC_00880	411469.EUBHAL_01320	6.15e-190	527.0	COG1235@1|root,COG1235@2|Bacteria,1TQ8E@1239|Firmicutes,249U2@186801|Clostridia,25VQ5@186806|Eubacteriaceae	186801|Clostridia	S	Metallo-beta-lactamase domain protein	yycJ	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2
HLKFIFDC_00881	411469.EUBHAL_01321	1.62e-58	181.0	COG3830@1|root,COG3830@2|Bacteria,1VENW@1239|Firmicutes,24QNV@186801|Clostridia,25X1Y@186806|Eubacteriaceae	186801|Clostridia	T	Belongs to the UPF0237 family	-	-	-	ko:K07166	-	-	-	-	ko00000	-	-	-	ACT_6
HLKFIFDC_00882	411469.EUBHAL_01322	0.0	879.0	COG2848@1|root,COG2848@2|Bacteria,1TQG8@1239|Firmicutes,247K4@186801|Clostridia,25V7Y@186806|Eubacteriaceae	186801|Clostridia	S	UPF0210 protein	-	-	-	ko:K09157	-	-	-	-	ko00000	-	-	-	DUF711
HLKFIFDC_00883	411469.EUBHAL_01324	1.14e-159	447.0	COG0745@1|root,COG0745@2|Bacteria,1TT12@1239|Firmicutes,24AB1@186801|Clostridia,25VWN@186806|Eubacteriaceae	186801|Clostridia	K	Response regulator receiver domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HLKFIFDC_00884	411469.EUBHAL_01325	1.19e-294	805.0	COG0642@1|root,COG2205@2|Bacteria,1TR7T@1239|Firmicutes,24CJ8@186801|Clostridia,25V38@186806|Eubacteriaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
HLKFIFDC_00885	1280698.AUJS01000027_gene2301	1.68e-154	434.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,27W3S@189330|Dorea	186801|Clostridia	V	COG COG1136 ABC-type antimicrobial peptide transport system, ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HLKFIFDC_00886	411461.DORFOR_00152	0.0	1529.0	COG0577@1|root,COG0577@2|Bacteria,1TQ8P@1239|Firmicutes,25E38@186801|Clostridia,27WB8@189330|Dorea	186801|Clostridia	V	COG COG0577 ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
HLKFIFDC_00889	411469.EUBHAL_01334	7.09e-135	385.0	COG1413@1|root,COG1413@2|Bacteria,1TXJS@1239|Firmicutes,25340@186801|Clostridia	186801|Clostridia	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
HLKFIFDC_00890	411469.EUBHAL_01335	5.58e-63	192.0	COG0457@1|root,COG0457@2|Bacteria,1VDUM@1239|Firmicutes,24NK8@186801|Clostridia	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00892	411469.EUBHAL_01337	9.92e-142	400.0	COG2357@1|root,COG2357@2|Bacteria,1UZBZ@1239|Firmicutes,24FD2@186801|Clostridia,25YFI@186806|Eubacteriaceae	186801|Clostridia	S	Region found in RelA / SpoT proteins	-	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
HLKFIFDC_00893	411469.EUBHAL_01338	2.01e-39	138.0	28KQ0@1|root,2ZA7Z@2|Bacteria,1V4X7@1239|Firmicutes,24E87@186801|Clostridia,25XIQ@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF3990)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3990
HLKFIFDC_00894	411469.EUBHAL_01339	1.29e-149	421.0	COG1396@1|root,COG1396@2|Bacteria,1V61Y@1239|Firmicutes,24E94@186801|Clostridia,25ZQF@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HLKFIFDC_00895	411469.EUBHAL_01340	1.39e-166	465.0	COG4912@1|root,COG4912@2|Bacteria,1TQII@1239|Firmicutes,248N8@186801|Clostridia,25W83@186806|Eubacteriaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
HLKFIFDC_00896	411469.EUBHAL_01341	0.0	991.0	COG0507@1|root,COG0507@2|Bacteria,1TR2Y@1239|Firmicutes,24B2Q@186801|Clostridia,25WMI@186806|Eubacteriaceae	186801|Clostridia	L	Uncharacterized conserved protein (DUF2075)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2075
HLKFIFDC_00897	411469.EUBHAL_01343	3.23e-247	678.0	COG2008@1|root,COG2008@2|Bacteria,1TPZI@1239|Firmicutes,248TR@186801|Clostridia,25V44@186806|Eubacteriaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	ltaE	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
HLKFIFDC_00898	411469.EUBHAL_01345	4.26e-291	795.0	COG0486@1|root,COG0486@2|Bacteria,1TQA8@1239|Firmicutes,247M4@186801|Clostridia,25UXB@186806|Eubacteriaceae	186801|Clostridia	S	Hydrogenase maturation GTPase HydF	hydF	-	-	-	-	-	-	-	-	-	-	-	MMR_HSR1
HLKFIFDC_00899	411469.EUBHAL_01348	0.0	872.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,25UUS@186806|Eubacteriaceae	186801|Clostridia	E	amino acid carrier protein	agcS	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
HLKFIFDC_00900	411469.EUBHAL_01350	1.86e-244	671.0	COG1975@1|root,COG1975@2|Bacteria,1UZDB@1239|Firmicutes,25D6N@186801|Clostridia,25WH9@186806|Eubacteriaceae	186801|Clostridia	O	XdhC and CoxI family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
HLKFIFDC_00901	411469.EUBHAL_01351	1.31e-245	674.0	COG0303@1|root,COG0303@2|Bacteria,1TP7F@1239|Firmicutes,247TZ@186801|Clostridia,25VS2@186806|Eubacteriaceae	186801|Clostridia	H	Probable molybdopterin binding domain	moeA2	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
HLKFIFDC_00902	411469.EUBHAL_01352	5.09e-124	353.0	COG0315@1|root,COG0315@2|Bacteria,1V3J4@1239|Firmicutes,24H9F@186801|Clostridia,25WTI@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
HLKFIFDC_00903	411469.EUBHAL_01353	0.0	1211.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia,25Y3P@186806|Eubacteriaceae	186801|Clostridia	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
HLKFIFDC_00904	411469.EUBHAL_01354	1.62e-115	330.0	COG1896@1|root,COG1896@2|Bacteria,1UIAE@1239|Firmicutes,25EFH@186801|Clostridia,25ZK2@186806|Eubacteriaceae	186801|Clostridia	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
HLKFIFDC_00905	411469.EUBHAL_01355	0.0	936.0	COG0366@1|root,COG0366@2|Bacteria,1TQFJ@1239|Firmicutes,249Y3@186801|Clostridia,25UUK@186806|Eubacteriaceae	186801|Clostridia	G	Alpha amylase, catalytic domain	-	-	3.2.1.133,3.2.1.135,3.2.1.54,3.5.4.33	ko:K01208,ko:K11991	ko00500,ko01100,map00500,map01100	-	R02112,R03122,R10223,R11262	RC00477	ko00000,ko00001,ko01000,ko03016	-	GH13	-	Alpha-amylase,Alpha-amylase_C,DUF1653,Malt_amylase_C
HLKFIFDC_00906	411469.EUBHAL_01356	1.61e-48	154.0	COG1925@1|root,COG1925@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	-	-	-	-	-	-	-	-	-	-	-	-	PTS-HPr
HLKFIFDC_00907	411469.EUBHAL_01357	1.28e-182	508.0	COG0834@1|root,COG0834@2|Bacteria,1TQUG@1239|Firmicutes,248UZ@186801|Clostridia,25ZFJ@186806|Eubacteriaceae	186801|Clostridia	ET	ABC transporter, substrate-binding protein, family 3	glnH1	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
HLKFIFDC_00908	411469.EUBHAL_01358	4.38e-140	397.0	COG0765@1|root,COG0765@2|Bacteria,1TPM3@1239|Firmicutes,24BKA@186801|Clostridia,25ZFK@186806|Eubacteriaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02029,ko:K02030,ko:K10009	ko02010,map02010	M00234,M00236	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.10,3.A.1.3.14	-	-	BPD_transp_1
HLKFIFDC_00909	411469.EUBHAL_01359	1.13e-168	472.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia,25VT5@186806|Eubacteriaceae	186801|Clostridia	E	Psort location CytoplasmicMembrane, score	glnQ1	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
HLKFIFDC_00910	411469.EUBHAL_01360	9.01e-180	501.0	COG0263@1|root,COG0263@2|Bacteria,1TPG6@1239|Firmicutes,2486P@186801|Clostridia,25W15@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
HLKFIFDC_00911	411469.EUBHAL_01361	2.88e-289	791.0	COG0014@1|root,COG0014@2|Bacteria,1TQ9V@1239|Firmicutes,248NX@186801|Clostridia,25VEY@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
HLKFIFDC_00913	411469.EUBHAL_01363	3.2e-305	831.0	2DCT9@1|root,2ZF90@2|Bacteria,1W3HQ@1239|Firmicutes,2577Y@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00914	411469.EUBHAL_01364	4.07e-175	489.0	COG2357@1|root,COG2357@2|Bacteria,1TSC9@1239|Firmicutes,25CET@186801|Clostridia,25ZIZ@186806|Eubacteriaceae	186801|Clostridia	S	RelA SpoT domain protein	-	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
HLKFIFDC_00915	411469.EUBHAL_01365	3.68e-216	600.0	COG0530@1|root,COG0530@2|Bacteria,1TRX0@1239|Firmicutes,24ABZ@186801|Clostridia,25V4F@186806|Eubacteriaceae	186801|Clostridia	P	K -dependent Na Ca exchanger family protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
HLKFIFDC_00916	411469.EUBHAL_01366	1.96e-194	540.0	2BHVM@1|root,32BZG@2|Bacteria,1UK71@1239|Firmicutes,25FNR@186801|Clostridia,25Z6A@186806|Eubacteriaceae	411469.EUBHAL_01366|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00917	411469.EUBHAL_01367	9.77e-198	554.0	COG0484@1|root,COG0484@2|Bacteria,1TS44@1239|Firmicutes,24A9N@186801|Clostridia,25Y6V@186806|Eubacteriaceae	186801|Clostridia	O	Psort location Cytoplasmic, score	CbpA	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
HLKFIFDC_00918	1160721.RBI_II00626	3.28e-109	320.0	COG0655@1|root,COG0655@2|Bacteria,1UI36@1239|Firmicutes,247R8@186801|Clostridia,3WGNE@541000|Ruminococcaceae	186801|Clostridia	S	PFAM NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
HLKFIFDC_00919	411469.EUBHAL_01369	0.0	2823.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1TPU5@1239|Firmicutes,2481F@186801|Clostridia,25VEA@186806|Eubacteriaceae	186801|Clostridia	I	CoA-substrate-specific enzyme activase	hgdC2	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229,HGD-D
HLKFIFDC_00920	411469.EUBHAL_01370	9.2e-87	254.0	COG1388@1|root,COG1388@2|Bacteria,1VKXM@1239|Firmicutes,24VM6@186801|Clostridia,25XS7@186806|Eubacteriaceae	186801|Clostridia	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
HLKFIFDC_00921	411469.EUBHAL_01371	5.51e-213	589.0	COG0598@1|root,COG0598@2|Bacteria,1TPI8@1239|Firmicutes,24956@186801|Clostridia,25VH3@186806|Eubacteriaceae	186801|Clostridia	P	CorA-like Mg2+ transporter protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
HLKFIFDC_00922	411469.EUBHAL_01373	2.92e-192	533.0	COG0705@1|root,COG0705@2|Bacteria,1TSBP@1239|Firmicutes,249D8@186801|Clostridia,25VBB@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
HLKFIFDC_00924	411469.EUBHAL_01375	1.56e-160	456.0	2E3Z2@1|root,32YW0@2|Bacteria,1VGF4@1239|Firmicutes,24PIY@186801|Clostridia,25X7D@186806|Eubacteriaceae	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	DUF2953
HLKFIFDC_00925	411469.EUBHAL_01376	1.21e-93	274.0	COG3874@1|root,COG3874@2|Bacteria,1V99U@1239|Firmicutes,24K00@186801|Clostridia,25WRI@186806|Eubacteriaceae	186801|Clostridia	S	Sporulation protein YtfJ (Spore_YtfJ)	-	-	-	-	-	-	-	-	-	-	-	-	Spore_YtfJ
HLKFIFDC_00926	1410632.JHWW01000001_gene1355	3.15e-34	117.0	COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes,24QNA@186801|Clostridia,27PS5@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Ribosomal L28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
HLKFIFDC_00927	411469.EUBHAL_01379	5.23e-77	229.0	COG1302@1|root,COG1302@2|Bacteria,1V731@1239|Firmicutes,24JIA@186801|Clostridia,25WQ4@186806|Eubacteriaceae	186801|Clostridia	S	Asp23 family, cell envelope-related function	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
HLKFIFDC_00928	411469.EUBHAL_01380	0.0	1070.0	COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,247XI@186801|Clostridia,25VT6@186806|Eubacteriaceae	186801|Clostridia	S	DAK2 domain fusion protein YloV	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
HLKFIFDC_00929	411469.EUBHAL_01381	0.0	1321.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia,25VDR@186806|Eubacteriaceae	186801|Clostridia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
HLKFIFDC_00930	411469.EUBHAL_01382	1.19e-171	479.0	COG2365@1|root,COG2365@2|Bacteria,1V851@1239|Firmicutes,24GVA@186801|Clostridia,25XEM@186806|Eubacteriaceae	186801|Clostridia	T	Tyrosine phosphatase family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	Y_phosphatase3
HLKFIFDC_00931	411469.EUBHAL_01383	1.05e-126	360.0	COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,24JHR@186801|Clostridia,25W9D@186806|Eubacteriaceae	186801|Clostridia	L	RNA methyltransferase, RsmD family	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
HLKFIFDC_00932	411469.EUBHAL_01384	4.43e-105	304.0	COG0669@1|root,COG0669@2|Bacteria,1V3MR@1239|Firmicutes,24HC3@186801|Clostridia,25WCF@186806|Eubacteriaceae	186801|Clostridia	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
HLKFIFDC_00933	411469.EUBHAL_01385	1.92e-98	291.0	COG0711@1|root,COG0711@2|Bacteria,1V97P@1239|Firmicutes,24JGQ@186801|Clostridia,25W81@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00934	411469.EUBHAL_01386	8.41e-201	559.0	COG3314@1|root,COG3314@2|Bacteria,1TR0V@1239|Firmicutes,247XA@186801|Clostridia	186801|Clostridia	S	Sporulation integral membrane protein YlbJ	ylbJ	-	-	-	-	-	-	-	-	-	-	-	Gate
HLKFIFDC_00935	411469.EUBHAL_01387	7.83e-123	350.0	COG1399@1|root,COG1399@2|Bacteria,1VEXU@1239|Firmicutes,24RKT@186801|Clostridia,25X1X@186806|Eubacteriaceae	186801|Clostridia	S	Cytoplasmic, score 8.87	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
HLKFIFDC_00936	411469.EUBHAL_01388	1.2e-37	125.0	COG0333@1|root,COG0333@2|Bacteria,1VEFI@1239|Firmicutes,24QM0@186801|Clostridia,25X9Z@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
HLKFIFDC_00937	411469.EUBHAL_01390	1.62e-170	478.0	COG1691@1|root,COG1691@2|Bacteria,1TP0Z@1239|Firmicutes,24815@186801|Clostridia,25UW6@186806|Eubacteriaceae	186801|Clostridia	S	AIR carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
HLKFIFDC_00938	411469.EUBHAL_01391	1.02e-268	743.0	COG1641@1|root,COG1641@2|Bacteria,1TPAV@1239|Firmicutes,247ZH@186801|Clostridia,25UX5@186806|Eubacteriaceae	186801|Clostridia	S	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
HLKFIFDC_00939	411469.EUBHAL_01392	4.14e-279	762.0	COG2768@1|root,COG2768@2|Bacteria,1TQAW@1239|Firmicutes,247IS@186801|Clostridia,25V4G@186806|Eubacteriaceae	186801|Clostridia	C	Domain of unknown function (DUF362)	-	-	-	ko:K07138	-	-	-	-	ko00000	-	-	-	DUF362,Fer4,Fer4_21,Fer4_6,Fer4_7,Fer4_9
HLKFIFDC_00940	411469.EUBHAL_01393	2.97e-41	135.0	COG2104@1|root,COG2104@2|Bacteria,1UQJ3@1239|Firmicutes,258AR@186801|Clostridia,25XPZ@186806|Eubacteriaceae	186801|Clostridia	H	ThiS family	-	-	-	-	-	-	-	-	-	-	-	-	ThiS
HLKFIFDC_00941	411469.EUBHAL_01394	2.29e-177	494.0	COG2022@1|root,COG2022@2|Bacteria,1TQZ1@1239|Firmicutes,247TJ@186801|Clostridia,25VDI@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
HLKFIFDC_00942	411469.EUBHAL_01395	2.64e-305	832.0	COG0502@1|root,COG0502@2|Bacteria,1TPEX@1239|Firmicutes,248PF@186801|Clostridia,25VR3@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	thiH	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
HLKFIFDC_00943	411469.EUBHAL_01396	1.21e-164	462.0	COG0352@1|root,COG0352@2|Bacteria,1V4SE@1239|Firmicutes,24JTR@186801|Clostridia,25WPB@186806|Eubacteriaceae	186801|Clostridia	H	Psort location Cytoplasmic, score	tenI	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06600	TMP-TENI
HLKFIFDC_00944	411469.EUBHAL_01397	3.19e-170	478.0	COG2510@1|root,COG2510@2|Bacteria,1V3VG@1239|Firmicutes,247SX@186801|Clostridia,25WFN@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K08978	-	-	-	-	ko00000,ko02000	2.A.7.2	-	-	EamA
HLKFIFDC_00945	411469.EUBHAL_01399	1.99e-295	808.0	COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,25CEM@186801|Clostridia,25UXU@186806|Eubacteriaceae	186801|Clostridia	F	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	Xan_ur_permease
HLKFIFDC_00946	411469.EUBHAL_01401	2.83e-81	242.0	COG1846@1|root,COG1846@2|Bacteria,1VEYN@1239|Firmicutes,24S21@186801|Clostridia,25XH4@186806|Eubacteriaceae	186801|Clostridia	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
HLKFIFDC_00947	411469.EUBHAL_01402	0.0	1091.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia,25UVM@186806|Eubacteriaceae	186801|Clostridia	V	ABC-type multidrug transport system, ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HLKFIFDC_00948	411469.EUBHAL_01403	0.0	1210.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,25UTB@186806|Eubacteriaceae	186801|Clostridia	V	ABC-type multidrug transport system, ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HLKFIFDC_00949	411469.EUBHAL_01404	0.0	903.0	COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,248ZB@186801|Clostridia,25V40@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
HLKFIFDC_00950	411469.EUBHAL_01405	2.49e-276	757.0	COG1457@1|root,COG1457@2|Bacteria,1TTBN@1239|Firmicutes,248EP@186801|Clostridia,25VIK@186806|Eubacteriaceae	186801|Clostridia	F	Psort location CytoplasmicMembrane, score 10.00	cytX	-	-	-	-	-	-	-	-	-	-	-	Transp_cyt_pur
HLKFIFDC_00951	411469.EUBHAL_01406	2.84e-155	435.0	COG0494@1|root,COG0494@2|Bacteria,1V42T@1239|Firmicutes,24ICB@186801|Clostridia	186801|Clostridia	L	NUDIX domain	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
HLKFIFDC_00952	411469.EUBHAL_01407	3.88e-123	350.0	COG4917@1|root,COG4917@2|Bacteria,1VAYC@1239|Firmicutes,24F8T@186801|Clostridia,25W1X@186806|Eubacteriaceae	186801|Clostridia	E	ethanolamine utilization protein EutP	eutP	-	-	ko:K04029	-	-	-	-	ko00000	-	-	-	PduV-EutP
HLKFIFDC_00953	411469.EUBHAL_01408	1.63e-208	578.0	COG0530@1|root,COG0530@2|Bacteria,1TRX0@1239|Firmicutes,24ABZ@186801|Clostridia,25V4F@186806|Eubacteriaceae	186801|Clostridia	P	K -dependent Na Ca exchanger family protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
HLKFIFDC_00954	411469.EUBHAL_01409	3.78e-205	570.0	COG0791@1|root,COG3103@1|root,COG0791@2|Bacteria,COG3103@2|Bacteria	2|Bacteria	T	Sh3 type 3 domain protein	iap	-	-	-	-	-	-	-	-	-	-	-	LysM,NLPC_P60,SH3_3
HLKFIFDC_00955	411469.EUBHAL_01410	5.98e-265	725.0	2DBS4@1|root,2ZAPG@2|Bacteria,1V2EV@1239|Firmicutes,24F58@186801|Clostridia,25W4K@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00956	411469.EUBHAL_01412	8.08e-154	432.0	COG4816@1|root,COG4816@2|Bacteria,1TPAQ@1239|Firmicutes,248W6@186801|Clostridia,25W9Z@186806|Eubacteriaceae	186801|Clostridia	E	BMC	-	-	-	ko:K04026	-	-	-	-	ko00000	-	-	-	BMC
HLKFIFDC_00957	411469.EUBHAL_01413	5.5e-161	450.0	COG4816@1|root,COG4816@2|Bacteria,1TPAQ@1239|Firmicutes,248W6@186801|Clostridia,25W9Z@186806|Eubacteriaceae	186801|Clostridia	E	BMC	-	-	-	ko:K04026	-	-	-	-	ko00000	-	-	-	BMC
HLKFIFDC_00958	411469.EUBHAL_01414	0.0	1170.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,247Z3@186801|Clostridia,25V6K@186806|Eubacteriaceae	186801|Clostridia	J	L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
HLKFIFDC_00959	411469.EUBHAL_01416	0.0	1180.0	COG3808@1|root,COG3808@2|Bacteria,1TNZI@1239|Firmicutes,248KS@186801|Clostridia,25V7G@186806|Eubacteriaceae	186801|Clostridia	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
HLKFIFDC_00960	411469.EUBHAL_01417	1.61e-88	259.0	2D9FD@1|root,32TT6@2|Bacteria,1VA9S@1239|Firmicutes,24NGK@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_00961	411469.EUBHAL_01419	3.53e-130	381.0	COG3757@1|root,COG3757@2|Bacteria,1UK1T@1239|Firmicutes,25FHH@186801|Clostridia,25ZDX@186806|Eubacteriaceae	186801|Clostridia	M	Glycosyl hydrolase family 25	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CW_binding_1,Glyco_hydro_25,fn3
HLKFIFDC_00962	411469.EUBHAL_01421	5.07e-125	355.0	COG4917@1|root,COG4917@2|Bacteria,1VAYC@1239|Firmicutes,24F8T@186801|Clostridia,25W1X@186806|Eubacteriaceae	186801|Clostridia	E	ethanolamine utilization protein EutP	eutP	-	-	ko:K04029	-	-	-	-	ko00000	-	-	-	PduV-EutP
HLKFIFDC_00964	411469.EUBHAL_01423	3.24e-162	456.0	COG5523@1|root,COG5523@2|Bacteria,1V6FC@1239|Firmicutes,24JPX@186801|Clostridia,25WP4@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	DUF975
HLKFIFDC_00966	411469.EUBHAL_01425	0.0	1247.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,1TPYV@1239|Firmicutes,248XC@186801|Clostridia,25VCF@186806|Eubacteriaceae	186801|Clostridia	H	Cytoplasmic, score	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
HLKFIFDC_00967	411469.EUBHAL_01426	0.0	1561.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1TPYV@1239|Firmicutes,248JB@186801|Clostridia,25VQ1@186806|Eubacteriaceae	186801|Clostridia	H	Psort location Cytoplasmic, score	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Pterin_bind,S-methyl_trans
HLKFIFDC_00968	411469.EUBHAL_01427	2.3e-227	625.0	COG1216@1|root,COG1216@2|Bacteria,1TSXW@1239|Firmicutes,2499G@186801|Clostridia,25XA3@186806|Eubacteriaceae	186801|Clostridia	S	Glycosyl transferase family 2	-	-	-	ko:K12992	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01005	-	GT2	-	Glycos_transf_2
HLKFIFDC_00969	411469.EUBHAL_01429	1.09e-253	697.0	COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,248RH@186801|Clostridia,25WXJ@186806|Eubacteriaceae	186801|Clostridia	K	Cell envelope-related transcriptional attenuator domain	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
HLKFIFDC_00970	411469.EUBHAL_01430	4.98e-105	304.0	COG0440@1|root,COG0440@2|Bacteria,1V2AJ@1239|Firmicutes,24HZM@186801|Clostridia,25WE8@186806|Eubacteriaceae	186801|Clostridia	E	acetolactate synthase, small	ilvN	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10025	ACT,ACT_5,ALS_ss_C
HLKFIFDC_00971	411469.EUBHAL_01432	2.76e-247	678.0	COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,25VBQ@186806|Eubacteriaceae	186801|Clostridia	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
HLKFIFDC_00972	411469.EUBHAL_01433	4.56e-244	671.0	2C2TA@1|root,2Z7T7@2|Bacteria,1TS53@1239|Firmicutes,248BA@186801|Clostridia,25VUC@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	FUSC_2
HLKFIFDC_00973	411469.EUBHAL_01435	1.2e-96	281.0	COG0394@1|root,COG0394@2|Bacteria,1V6SG@1239|Firmicutes,24MMZ@186801|Clostridia,25X28@186806|Eubacteriaceae	186801|Clostridia	T	Low molecular weight phosphotyrosine protein phosphatase	yfkJ	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
HLKFIFDC_00974	411469.EUBHAL_01436	6.61e-231	638.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	ko:K03220	-	M00332	-	-	ko00000,ko00002,ko02044	3.A.6.1	-	-	DUF4123,FHA,Trans_reg_C,Yop-YscD_cpl
HLKFIFDC_00975	411469.EUBHAL_01437	2.76e-131	387.0	COG1033@1|root,COG1033@2|Bacteria,1VHSF@1239|Firmicutes,24R7H@186801|Clostridia,25XTN@186806|Eubacteriaceae	186801|Clostridia	M	YARHG domain	-	-	-	-	-	-	-	-	-	-	-	-	YARHG,zinc_ribbon_2
HLKFIFDC_00977	1235802.C823_03166	1.29e-138	432.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,24BJ8@186801|Clostridia,25W9R@186806|Eubacteriaceae	186801|Clostridia	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,PASTA,PDZ_2,Pkinase,YARHG
HLKFIFDC_00978	658655.HMPREF0988_01687	6.35e-40	166.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,24BJ8@186801|Clostridia,27IRK@186928|unclassified Lachnospiraceae	186801|Clostridia	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PASTA,Pkinase,YARHG
HLKFIFDC_00979	515620.EUBELI_20117	1.89e-06	60.1	COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,2481P@186801|Clostridia,25YIY@186806|Eubacteriaceae	186801|Clostridia	G	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	pulA	-	3.2.1.41	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	-	R02111	-	ko00000,ko00001,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
HLKFIFDC_00980	1458462.JNLK01000001_gene1059	5.29e-106	345.0	COG0515@1|root,COG0515@2|Bacteria,1UZ08@1239|Firmicutes,24EK0@186801|Clostridia,27KFX@186928|unclassified Lachnospiraceae	186801|Clostridia	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
HLKFIFDC_00982	397290.C810_03518	2.44e-240	696.0	COG1131@1|root,COG1131@2|Bacteria,1V0ED@1239|Firmicutes,24BB5@186801|Clostridia,27IN8@186928|unclassified Lachnospiraceae	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran,FHA
HLKFIFDC_00983	397290.C810_03511	1.2e-79	246.0	COG0631@1|root,COG0631@2|Bacteria,1V5HX@1239|Firmicutes,24IV0@186801|Clostridia,27MRE@186928|unclassified Lachnospiraceae	186801|Clostridia	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PP2C_2
HLKFIFDC_00984	1235799.C818_01945	2.76e-34	129.0	COG1716@1|root,COG1716@2|Bacteria,1UZ57@1239|Firmicutes,24PC6@186801|Clostridia,27MIP@186928|unclassified Lachnospiraceae	186801|Clostridia	T	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
HLKFIFDC_00985	1120980.JQKH01000016_gene1916	2.88e-07	62.4	COG1716@1|root,COG1716@2|Bacteria,1PUHS@1224|Proteobacteria,2WAU3@28216|Betaproteobacteria,2KQST@206351|Neisseriales	206351|Neisseriales	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Trypsin_2
HLKFIFDC_00986	397290.C810_03514	7.01e-102	319.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,24BJ8@186801|Clostridia,27R6V@186928|unclassified Lachnospiraceae	186801|Clostridia	KLT	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,PASTA,PDZ_2,Pkinase,YARHG
HLKFIFDC_00987	1410626.JHXB01000001_gene2104	2.82e-65	212.0	COG0631@1|root,COG0631@2|Bacteria,1V094@1239|Firmicutes,24N9G@186801|Clostridia,27NCW@186928|unclassified Lachnospiraceae	186801|Clostridia	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2,SpoIIE
HLKFIFDC_00988	397290.C810_03516	1.56e-45	161.0	COG1716@1|root,COG1716@2|Bacteria,1UZ57@1239|Firmicutes,24PC6@186801|Clostridia,27MIP@186928|unclassified Lachnospiraceae	186801|Clostridia	T	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
HLKFIFDC_00989	411469.EUBHAL_01020	2.87e-107	347.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,24BJ8@186801|Clostridia,25W9R@186806|Eubacteriaceae	186801|Clostridia	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
HLKFIFDC_00990	411469.EUBHAL_01020	2.43e-104	336.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,24BJ8@186801|Clostridia,25W9R@186806|Eubacteriaceae	186801|Clostridia	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
HLKFIFDC_00991	411469.EUBHAL_01440	1.05e-219	612.0	COG0860@1|root,COG0860@2|Bacteria,1UZ49@1239|Firmicutes,25F7R@186801|Clostridia,25X2G@186806|Eubacteriaceae	186801|Clostridia	M	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,Big_2,GBS_Bsp-like,Glucosaminidase,RicinB_lectin_2,fn3
HLKFIFDC_00992	411469.EUBHAL_01450	7.9e-305	832.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,25URS@186806|Eubacteriaceae	186801|Clostridia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
HLKFIFDC_00993	411469.EUBHAL_01452	1.61e-96	282.0	COG4894@1|root,COG4894@2|Bacteria,1V3WA@1239|Firmicutes,24MB0@186801|Clostridia,25WX5@186806|Eubacteriaceae	186801|Clostridia	S	LURP-one-related	-	-	-	-	-	-	-	-	-	-	-	-	LOR
HLKFIFDC_00994	411469.EUBHAL_01453	4.77e-181	504.0	COG0300@1|root,COG0300@2|Bacteria,1UZHA@1239|Firmicutes,248C8@186801|Clostridia,25VB0@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
HLKFIFDC_00995	411469.EUBHAL_01454	0.0	905.0	COG0569@1|root,COG0569@2|Bacteria,1TPNS@1239|Firmicutes,24830@186801|Clostridia,25V3H@186806|Eubacteriaceae	186801|Clostridia	P	Potassium transporter peripheral membrane component	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
HLKFIFDC_00996	411469.EUBHAL_01455	0.0	950.0	COG0168@1|root,COG0168@2|Bacteria,1TPAF@1239|Firmicutes,248K4@186801|Clostridia,25US6@186806|Eubacteriaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
HLKFIFDC_00997	411469.EUBHAL_01456	5.03e-39	130.0	COG1918@1|root,COG1918@2|Bacteria,1VEYA@1239|Firmicutes,24QKX@186801|Clostridia,25X97@186806|Eubacteriaceae	186801|Clostridia	P	Fe2 transport system protein A	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
HLKFIFDC_00998	411469.EUBHAL_01457	5.03e-43	140.0	COG1918@1|root,COG1918@2|Bacteria,1VEHC@1239|Firmicutes,24QKE@186801|Clostridia,25XAZ@186806|Eubacteriaceae	186801|Clostridia	P	Fe2 transport system protein A	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
HLKFIFDC_00999	411469.EUBHAL_01458	0.0	1419.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,24885@186801|Clostridia,25V92@186806|Eubacteriaceae	186801|Clostridia	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
HLKFIFDC_01001	411469.EUBHAL_01460	1.02e-108	313.0	COG0735@1|root,COG0735@2|Bacteria,1V6DP@1239|Firmicutes,24K9H@186801|Clostridia,25X0Q@186806|Eubacteriaceae	186801|Clostridia	P	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
HLKFIFDC_01002	1121115.AXVN01000065_gene686	1.63e-45	150.0	COG0239@1|root,COG0239@2|Bacteria,1TTU1@1239|Firmicutes,259CY@186801|Clostridia,3Y0J4@572511|Blautia	186801|Clostridia	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
HLKFIFDC_01003	411469.EUBHAL_02984	4.35e-301	825.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,25UUS@186806|Eubacteriaceae	186801|Clostridia	E	amino acid carrier protein	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
HLKFIFDC_01004	411469.EUBHAL_02983	4.59e-247	678.0	COG1063@1|root,COG1063@2|Bacteria,1TQSR@1239|Firmicutes,248KM@186801|Clostridia,25VBS@186806|Eubacteriaceae	186801|Clostridia	C	Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate	-	-	1.1.1.405	ko:K05352	ko00040,ko01100,map00040,map01100	-	R01525	RC00089	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N,Glu_dehyd_C
HLKFIFDC_01005	411469.EUBHAL_02982	1.21e-166	466.0	COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,248E6@186801|Clostridia,25W5N@186806|Eubacteriaceae	186801|Clostridia	I	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate	-	-	2.7.7.40,2.7.7.60	ko:K00991,ko:K21030	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	M00096	R02921,R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,adh_short
HLKFIFDC_01006	411469.EUBHAL_02981	0.0	949.0	COG0169@1|root,COG1418@1|root,COG0169@2|Bacteria,COG1418@2|Bacteria,1V70P@1239|Firmicutes,24JTJ@186801|Clostridia,25WKW@186806|Eubacteriaceae	186801|Clostridia	E	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
HLKFIFDC_01007	411469.EUBHAL_02980	3.13e-160	449.0	COG2323@1|root,COG2323@2|Bacteria,1TRWQ@1239|Firmicutes,24CFP@186801|Clostridia,25ZH3@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF421
HLKFIFDC_01008	411469.EUBHAL_02978	1.86e-19	81.6	COG1013@1|root,COG1013@2|Bacteria,1TPF0@1239|Firmicutes,24BE5@186801|Clostridia,25VQ8@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	porB	-	1.2.7.1	ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
HLKFIFDC_01009	903814.ELI_2787	3.02e-183	513.0	COG1013@1|root,COG1013@2|Bacteria,1TPF0@1239|Firmicutes,24BE5@186801|Clostridia,25VQ8@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	porB	-	1.2.7.1	ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
HLKFIFDC_01010	411469.EUBHAL_02976	5.79e-92	270.0	COG1610@1|root,COG1610@2|Bacteria,1V6F2@1239|Firmicutes,24JB0@186801|Clostridia,25WJB@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
HLKFIFDC_01011	411469.EUBHAL_02972	0.0	1665.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,2484Y@186801|Clostridia,25V0K@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
HLKFIFDC_01012	411469.EUBHAL_02971	2.93e-198	553.0	COG1376@1|root,COG1376@2|Bacteria,1UK0I@1239|Firmicutes,249X8@186801|Clostridia,25W21@186806|Eubacteriaceae	186801|Clostridia	V	L,D-transpeptidase catalytic domain	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	DUF5011,YkuD
HLKFIFDC_01013	411469.EUBHAL_02970	3.36e-88	258.0	COG0346@1|root,COG0346@2|Bacteria,1V6K3@1239|Firmicutes,24J94@186801|Clostridia,25WTG@186806|Eubacteriaceae	186801|Clostridia	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	gloA	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
HLKFIFDC_01014	411469.EUBHAL_02969	0.0	1627.0	COG5009@1|root,COG5009@2|Bacteria,1UI0H@1239|Firmicutes,25E95@186801|Clostridia,25ZU7@186806|Eubacteriaceae	186801|Clostridia	M	Psort location Extracellular, score 9.55	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
HLKFIFDC_01015	411469.EUBHAL_02964	3.27e-71	215.0	2ANER@1|root,315MJ@2|Bacteria,1V6SU@1239|Firmicutes,24JBZ@186801|Clostridia,25WI2@186806|Eubacteriaceae	186801|Clostridia	S	Stage V sporulation protein AE	spoVAE	-	-	ko:K06407	-	-	-	-	ko00000	-	-	-	SpoVAC_SpoVAEB
HLKFIFDC_01016	411469.EUBHAL_02963	9.97e-245	672.0	COG0332@1|root,COG0332@2|Bacteria,1TPDE@1239|Firmicutes,25EAS@186801|Clostridia,25ZU6@186806|Eubacteriaceae	186801|Clostridia	I	Stage V sporulation protein AD (SpoVAD)	spoVAD	-	-	ko:K06406	-	-	-	-	ko00000	-	-	-	SpoVAD
HLKFIFDC_01017	411469.EUBHAL_02962	3.17e-187	519.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,248GJ@186801|Clostridia,25V81@186806|Eubacteriaceae	186801|Clostridia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA1	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
HLKFIFDC_01019	411469.EUBHAL_02960	1.37e-187	524.0	COG0526@1|root,COG0526@2|Bacteria,1UY9A@1239|Firmicutes,24C03@186801|Clostridia,25VZK@186806|Eubacteriaceae	186801|Clostridia	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
HLKFIFDC_01020	411469.EUBHAL_02959	1.64e-203	563.0	COG0348@1|root,COG0348@2|Bacteria,1TPHF@1239|Firmicutes,247KH@186801|Clostridia,25V01@186806|Eubacteriaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5
HLKFIFDC_01021	411469.EUBHAL_02957	1.1e-155	437.0	COG0745@1|root,COG0745@2|Bacteria,1TSRR@1239|Firmicutes,24AG3@186801|Clostridia,25W0I@186806|Eubacteriaceae	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	cutR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HLKFIFDC_01022	411469.EUBHAL_02956	8.71e-259	711.0	COG0642@1|root,COG2205@2|Bacteria,1UHQC@1239|Firmicutes,2496X@186801|Clostridia,25V5C@186806|Eubacteriaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	arlS	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
HLKFIFDC_01023	411469.EUBHAL_02955	4.56e-104	300.0	2ANER@1|root,31DDD@2|Bacteria,1V46U@1239|Firmicutes,24JDI@186801|Clostridia,25WKZ@186806|Eubacteriaceae	186801|Clostridia	S	stage V sporulation protein AC	spoVAC	-	-	ko:K06405	-	-	-	-	ko00000	-	-	-	SpoVAC_SpoVAEB
HLKFIFDC_01024	411469.EUBHAL_02954	3.98e-230	633.0	COG1893@1|root,COG1893@2|Bacteria,1UM1M@1239|Firmicutes,249J4@186801|Clostridia,25W78@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
HLKFIFDC_01025	411469.EUBHAL_02953	8.51e-137	387.0	COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,24836@186801|Clostridia,25VE4@186806|Eubacteriaceae	186801|Clostridia	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
HLKFIFDC_01026	411469.EUBHAL_02952	0.0	1450.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,247SH@186801|Clostridia,25VQG@186806|Eubacteriaceae	186801|Clostridia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
HLKFIFDC_01027	411469.EUBHAL_02951	2.67e-308	840.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,2481T@186801|Clostridia,25VCR@186806|Eubacteriaceae	186801|Clostridia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
HLKFIFDC_01028	411469.EUBHAL_02950	8.86e-133	377.0	COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,247QY@186801|Clostridia,25VNY@186806|Eubacteriaceae	186801|Clostridia	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
HLKFIFDC_01029	411469.EUBHAL_02949	2.05e-295	808.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,25VD0@186806|Eubacteriaceae	186801|Clostridia	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
HLKFIFDC_01030	411469.EUBHAL_02948	1.69e-41	136.0	2BX75@1|root,32YCI@2|Bacteria,1VEDY@1239|Firmicutes,24QPW@186801|Clostridia,25XFP@186806|Eubacteriaceae	186801|Clostridia	S	NOG16862 non supervised orthologous group	sasP	-	-	ko:K06421	-	-	-	-	ko00000	-	-	-	SASP
HLKFIFDC_01031	411469.EUBHAL_02947	9.08e-157	439.0	COG0546@1|root,COG0546@2|Bacteria,1V3YI@1239|Firmicutes,24CRF@186801|Clostridia,25WBF@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
HLKFIFDC_01032	411469.EUBHAL_02946	4.37e-249	683.0	COG1304@1|root,COG1304@2|Bacteria,1TPC4@1239|Firmicutes,249TX@186801|Clostridia,25W2N@186806|Eubacteriaceae	186801|Clostridia	C	FMN-dependent dehydrogenase	lldD	-	-	-	-	-	-	-	-	-	-	-	FMN_dh
HLKFIFDC_01033	411469.EUBHAL_02945	1.16e-268	737.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,248FS@186801|Clostridia,25VIQ@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
HLKFIFDC_01035	411469.EUBHAL_02941	1.68e-316	865.0	COG2239@1|root,COG2239@2|Bacteria,1TP4V@1239|Firmicutes,2481R@186801|Clostridia,25VPU@186806|Eubacteriaceae	186801|Clostridia	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
HLKFIFDC_01036	411469.EUBHAL_02939	1.26e-122	349.0	COG1443@1|root,COG1443@2|Bacteria,1V41D@1239|Firmicutes,24KU4@186801|Clostridia,25WM3@186806|Eubacteriaceae	186801|Clostridia	I	NUDIX domain	idi	-	-	-	-	-	-	-	-	-	-	-	NUDIX
HLKFIFDC_01037	411469.EUBHAL_02707	2.61e-303	825.0	COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,24969@186801|Clostridia,25UU2@186806|Eubacteriaceae	186801|Clostridia	E	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	dapL	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
HLKFIFDC_01038	411469.EUBHAL_02706	2.6e-207	573.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,24AGY@186801|Clostridia,25VMV@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
HLKFIFDC_01039	411469.EUBHAL_02705	1.17e-117	338.0	COG3707@1|root,COG3707@2|Bacteria,1V2S1@1239|Firmicutes,24EWG@186801|Clostridia,25WNT@186806|Eubacteriaceae	186801|Clostridia	K	ANTAR domain	-	-	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR
HLKFIFDC_01040	411469.EUBHAL_02704	0.0	905.0	COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,2489S@186801|Clostridia,25VDK@186806|Eubacteriaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
HLKFIFDC_01041	411469.EUBHAL_02703	0.0	2108.0	COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,2498I@186801|Clostridia,25UTY@186806|Eubacteriaceae	186801|Clostridia	F	carbamoylphosphate synthase large subunit	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,DAP_epimerase,MGS
HLKFIFDC_01042	411469.EUBHAL_02702	9.52e-265	724.0	COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,247Q8@186801|Clostridia,25V65@186806|Eubacteriaceae	186801|Clostridia	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
HLKFIFDC_01043	411469.EUBHAL_02701	7.3e-143	402.0	COG3409@1|root,COG3409@2|Bacteria,1TS29@1239|Firmicutes,247SQ@186801|Clostridia,25VVN@186806|Eubacteriaceae	186801|Clostridia	M	Peptidoglycan binding domain protein	sleC	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,SpoIID
HLKFIFDC_01044	411469.EUBHAL_02700	0.0	1127.0	COG1961@1|root,COG1961@2|Bacteria,1TRVQ@1239|Firmicutes,249AZ@186801|Clostridia,25VK9@186806|Eubacteriaceae	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
HLKFIFDC_01047	411469.EUBHAL_02694	5.84e-163	484.0	COG3378@1|root,2ZVRZ@2|Bacteria,1V48K@1239|Firmicutes,25DUJ@186801|Clostridia	186801|Clostridia	KL	Phage plasmid primase P4 family	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01048	411469.EUBHAL_02675	5.02e-34	122.0	28PM6@1|root,2Z8J4@2|Bacteria,1UXZE@1239|Firmicutes,24B7N@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01050	411469.EUBHAL_02673	2.11e-170	479.0	28HEE@1|root,2Z7QU@2|Bacteria,1TVQR@1239|Firmicutes,248QB@186801|Clostridia,25Y88@186806|Eubacteriaceae	186801|Clostridia	S	Domain of unknown function (DUF932)	-	-	-	-	-	-	-	-	-	-	-	-	DUF932
HLKFIFDC_01051	411469.EUBHAL_02672	1.89e-158	444.0	COG1961@1|root,COG1961@2|Bacteria,1U31Z@1239|Firmicutes,249GR@186801|Clostridia	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Resolvase
HLKFIFDC_01052	411469.EUBHAL_01615	5.46e-168	473.0	COG5464@1|root,COG5464@2|Bacteria,1TS6U@1239|Firmicutes,24A2X@186801|Clostridia,25WK9@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
HLKFIFDC_01053	411469.EUBHAL_01615	3.28e-32	119.0	COG5464@1|root,COG5464@2|Bacteria,1TS6U@1239|Firmicutes,24A2X@186801|Clostridia,25WK9@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
HLKFIFDC_01054	1280698.AUJS01000094_gene604	2e-89	269.0	COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,248UI@186801|Clostridia,27W2F@189330|Dorea	186801|Clostridia	L	Transposase, Mutator family	-	-	-	ko:K07493	-	-	-	-	ko00000	-	-	-	Transposase_mut
HLKFIFDC_01055	1256908.HMPREF0373_00353	6.98e-184	518.0	COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,248UI@186801|Clostridia,25VGM@186806|Eubacteriaceae	186801|Clostridia	L	Transposase, Mutator family	-	-	-	ko:K07493	-	-	-	-	ko00000	-	-	-	Transposase_mut
HLKFIFDC_01056	411469.EUBHAL_02836	1.32e-155	463.0	2DWUM@1|root,341YW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01057	411469.EUBHAL_00399	3.28e-12	70.5	COG1653@1|root,COG1653@2|Bacteria,1VE90@1239|Firmicutes,24Q7Y@186801|Clostridia	186801|Clostridia	G	transport	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01058	1410624.JNKK01000065_gene1264	1.12e-74	238.0	2BJ9Z@1|root,32DJR@2|Bacteria,1UP8S@1239|Firmicutes,25H90@186801|Clostridia,27Q6K@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01059	500632.CLONEX_00782	1.48e-63	197.0	COG1959@1|root,COG1959@2|Bacteria,1V6U4@1239|Firmicutes,25CBZ@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
HLKFIFDC_01061	500632.CLONEX_00778	2.67e-183	513.0	COG4509@1|root,COG4509@2|Bacteria,1V2EF@1239|Firmicutes,24CIH@186801|Clostridia	186801|Clostridia	S	sortase, SrtB family	-	-	3.4.22.70	ko:K08600	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
HLKFIFDC_01062	500632.CLONEX_00777	1.31e-165	476.0	2E0JX@1|root,32W5D@2|Bacteria,1VC57@1239|Firmicutes,24QG1@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01063	500632.CLONEX_00776	1.08e-104	305.0	COG0681@1|root,COG0681@2|Bacteria,1V954@1239|Firmicutes,24JWF@186801|Clostridia	186801|Clostridia	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S26
HLKFIFDC_01064	411470.RUMGNA_02926	0.0	3576.0	2C0GX@1|root,33PQ2@2|Bacteria,1VSSZ@1239|Firmicutes,24YT4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01065	500632.CLONEX_00784	9.94e-186	538.0	COG2508@1|root,COG2508@2|Bacteria,1TTA0@1239|Firmicutes,248HN@186801|Clostridia	186801|Clostridia	QT	Psort location Cytoplasmic, score	-	-	-	ko:K09684	-	-	-	-	ko00000,ko03000	-	-	-	HTH_30,PucR
HLKFIFDC_01066	1280698.AUJS01000004_gene2869	1.19e-44	156.0	2EFPH@1|root,339FG@2|Bacteria,1V4NH@1239|Firmicutes,24X74@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01067	1280698.AUJS01000004_gene2868	4.7e-139	402.0	COG3764@1|root,COG3764@2|Bacteria,1UN9R@1239|Firmicutes,24CEQ@186801|Clostridia,27WSA@189330|Dorea	186801|Clostridia	M	Sortase family	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
HLKFIFDC_01068	1280698.AUJS01000004_gene2867	2.94e-200	578.0	COG4932@1|root,COG4932@2|Bacteria,1UXYC@1239|Firmicutes,25MH3@186801|Clostridia,27X03@189330|Dorea	186801|Clostridia	M	Gram-positive pilin backbone subunit 2, Cna-B-like domain	-	-	-	-	-	-	-	-	-	-	-	-	GramPos_pilinBB
HLKFIFDC_01069	1280698.AUJS01000004_gene2866	0.0	4137.0	2CBRJ@1|root,2Z7W0@2|Bacteria,1TS6M@1239|Firmicutes,24XT3@186801|Clostridia	186801|Clostridia	S	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Cna_B
HLKFIFDC_01070	500632.CLONEX_00785	1.25e-304	835.0	COG1959@1|root,COG3437@1|root,COG1959@2|Bacteria,COG3437@2|Bacteria	2|Bacteria	T	response regulator, receiver	-	-	-	ko:K13771	ko05132,map05132	-	-	-	ko00000,ko00001,ko03000	-	-	-	GGDEF,HD,HD_5,Rrf2
HLKFIFDC_01071	500632.CLONEX_00772	0.0	897.0	COG2508@1|root,COG2508@2|Bacteria,1TTA0@1239|Firmicutes,248HN@186801|Clostridia	186801|Clostridia	QT	Psort location Cytoplasmic, score	-	-	-	ko:K09684	-	-	-	-	ko00000,ko03000	-	-	-	HTH_30,PucR
HLKFIFDC_01072	411469.EUBHAL_03142	3.38e-88	259.0	2DMPJ@1|root,32SWG@2|Bacteria,1V7RA@1239|Firmicutes,24NGU@186801|Clostridia,25XF2@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01074	411469.EUBHAL_01728	1.37e-25	103.0	COG5464@1|root,COG5464@2|Bacteria,1UA0N@1239|Firmicutes,247X9@186801|Clostridia,25WKX@186806|Eubacteriaceae	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
HLKFIFDC_01075	1321782.HMPREF1986_00390	1.4e-31	111.0	2EC10@1|root,33609@2|Bacteria,1VIKS@1239|Firmicutes,24Q57@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF3791)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3791
HLKFIFDC_01076	1095750.HMPREF9970_0730	9.33e-44	142.0	2DMVX@1|root,32U0C@2|Bacteria,1VBJ1@1239|Firmicutes,25PPR@186801|Clostridia,1HWFN@1164882|Lachnoanaerobaculum	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01077	610130.Closa_3692	8.86e-96	280.0	2DMYF@1|root,32UDM@2|Bacteria,1V0JJ@1239|Firmicutes,24DJ4@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF3990)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3990
HLKFIFDC_01078	411469.EUBHAL_01599	3.39e-167	468.0	COG3409@1|root,COG3409@2|Bacteria,1TS29@1239|Firmicutes,247SQ@186801|Clostridia,25W6G@186806|Eubacteriaceae	186801|Clostridia	M	Peptidoglycan binding domain protein	sleC	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,SpoIID
HLKFIFDC_01079	411469.EUBHAL_01598	1.22e-160	451.0	COG0539@1|root,COG0539@2|Bacteria,1UYC5@1239|Firmicutes,24AJ1@186801|Clostridia,25WEN@186806|Eubacteriaceae	186801|Clostridia	J	Ribosomal protein S1-like RNA-binding domain	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
HLKFIFDC_01080	411469.EUBHAL_01597	1.83e-173	483.0	COG1636@1|root,COG1636@2|Bacteria,1TT7H@1239|Firmicutes,248EA@186801|Clostridia,25W0V@186806|Eubacteriaceae	186801|Clostridia	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queH	-	1.17.99.6	ko:K09765	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF208
HLKFIFDC_01081	411469.EUBHAL_01596	9.89e-76	226.0	COG2198@1|root,COG2198@2|Bacteria,1V7T6@1239|Firmicutes,25CZG@186801|Clostridia	186801|Clostridia	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
HLKFIFDC_01082	411469.EUBHAL_01595	0.0	1298.0	COG2199@1|root,COG3437@1|root,COG2199@2|Bacteria,COG3437@2|Bacteria,1UQJH@1239|Firmicutes,248UM@186801|Clostridia,25V1R@186806|Eubacteriaceae	186801|Clostridia	T	Psort location Cytoplasmic, score	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GGDEF,HD,HD_5,Response_reg
HLKFIFDC_01083	1293054.HSACCH_00252	3.13e-10	60.5	COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia	186801|Clostridia	CQ	Carbon dioxide concentrating mechanism carboxysome shell protein	-	-	-	-	-	-	-	-	-	-	-	-	BMC
HLKFIFDC_01084	411469.EUBHAL_01592	0.0	897.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,25VBX@186806|Eubacteriaceae	186801|Clostridia	P	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
HLKFIFDC_01085	411469.EUBHAL_01591	0.0	2076.0	COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,2491S@186801|Clostridia,25V9F@186806|Eubacteriaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 10.00	czcA	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
HLKFIFDC_01086	411469.EUBHAL_01590	3.65e-221	608.0	COG2816@1|root,COG2816@2|Bacteria,1TRMF@1239|Firmicutes,24AXA@186801|Clostridia,25W43@186806|Eubacteriaceae	186801|Clostridia	L	NADH pyrophosphatase zinc ribbon domain	nudC	-	3.6.1.22	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	-	R00103,R03004,R11104	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,NUDIX-like,zf-NADH-PPase
HLKFIFDC_01087	411469.EUBHAL_01589	4.98e-273	749.0	COG1301@1|root,COG1301@2|Bacteria,1TPME@1239|Firmicutes,247UX@186801|Clostridia,25UR9@186806|Eubacteriaceae	186801|Clostridia	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
HLKFIFDC_01088	411469.EUBHAL_01588	1.18e-72	218.0	2DSE8@1|root,33FSA@2|Bacteria,1UK72@1239|Firmicutes,25FNS@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HLKFIFDC_01090	411469.EUBHAL_01586	4.65e-194	539.0	COG0348@1|root,COG0348@2|Bacteria,1TRZZ@1239|Firmicutes,24A2P@186801|Clostridia	186801|Clostridia	C	4Fe-4S binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_9
HLKFIFDC_01091	411469.EUBHAL_01583	2.63e-57	179.0	COG0348@1|root,COG0348@2|Bacteria,1UHUA@1239|Firmicutes,24BED@186801|Clostridia	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
HLKFIFDC_01092	411469.EUBHAL_01582	7.74e-26	96.7	COG1245@1|root,COG1245@2|Bacteria	2|Bacteria	C	4Fe-4S binding domain	napG	-	1.8.99.2	ko:K00395,ko:K02572,ko:K02573,ko:K02574	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Fer4_5,Fer4_7
HLKFIFDC_01094	1280698.AUJS01000017_gene1832	6.52e-218	601.0	2BCDC@1|root,325YT@2|Bacteria,1VD8M@1239|Firmicutes,24MU9@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01095	411469.EUBHAL_01579	3.46e-151	426.0	COG0664@1|root,COG0664@2|Bacteria,1V2MV@1239|Firmicutes,24B7K@186801|Clostridia,25WMM@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
HLKFIFDC_01096	411469.EUBHAL_01578	0.0	1103.0	COG0446@1|root,COG0607@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,1TPWW@1239|Firmicutes,2484C@186801|Clostridia,25UZM@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	cdr	-	-	-	-	-	-	-	-	-	-	-	DrsE_2,Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA
HLKFIFDC_01097	411469.EUBHAL_01577	7.75e-62	190.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,25WU9@186806|Eubacteriaceae	186801|Clostridia	O	Belongs to the thioredoxin family	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
HLKFIFDC_01098	411469.EUBHAL_01576	4.63e-24	90.5	2BA71@1|root,2ZUYK@2|Bacteria,1W3C7@1239|Firmicutes,24S22@186801|Clostridia	186801|Clostridia	-	-	-	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	-
HLKFIFDC_01099	411469.EUBHAL_01575	2.22e-67	210.0	COG2865@1|root,COG2865@2|Bacteria,1TRTZ@1239|Firmicutes,25CHW@186801|Clostridia,25WTS@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4,HTH_11,HTH_24
HLKFIFDC_01100	1280698.AUJS01000017_gene1837	1.75e-93	285.0	COG1522@1|root,COG2865@1|root,COG1522@2|Bacteria,COG2865@2|Bacteria,1TRTZ@1239|Firmicutes,25CHW@186801|Clostridia,27W54@189330|Dorea	186801|Clostridia	K	Putative ATP-dependent DNA helicase recG C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4,HTH_11,HTH_24
HLKFIFDC_01101	411469.EUBHAL_01573	1.13e-307	840.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia	186801|Clostridia	V	Mate efflux family protein	mepA_10	-	-	-	-	-	-	-	-	-	-	-	MatE
HLKFIFDC_01102	411469.EUBHAL_01572	7.31e-40	133.0	COG2723@1|root,COG2723@2|Bacteria	2|Bacteria	G	beta-glucosidase activity	-	-	3.2.1.86	ko:K01223	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT1	-	Glyco_hydro_1
HLKFIFDC_01103	397288.C806_01701	1.47e-31	111.0	COG3655@1|root,COG3655@2|Bacteria,1VM6P@1239|Firmicutes,24UWM@186801|Clostridia,27SJI@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
HLKFIFDC_01104	1121115.AXVN01000176_gene3753	5.44e-06	47.0	2APSG@1|root,31EWH@2|Bacteria,1V7XT@1239|Firmicutes,24JQX@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Tn7_Tnp_TnsA_N
HLKFIFDC_01105	411469.EUBHAL_00499	3.99e-12	60.8	COG2405@1|root,COG2405@2|Bacteria,1TYRS@1239|Firmicutes,259XH@186801|Clostridia,25Z26@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01106	936596.HMPREF1495_1952	8.55e-41	136.0	2E6G2@1|root,3313C@2|Bacteria,1VIYK@1239|Firmicutes,24V8K@186801|Clostridia,1HVU9@1164882|Lachnoanaerobaculum	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	UPF0175
HLKFIFDC_01107	511680.BUTYVIB_02249	3.73e-283	774.0	2E4RQ@1|root,32ZK7@2|Bacteria,1VI66@1239|Firmicutes,24TZR@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01108	511680.BUTYVIB_02250	3.91e-125	357.0	COG1595@1|root,COG1595@2|Bacteria,1UZ1M@1239|Firmicutes,24AUS@186801|Clostridia	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HLKFIFDC_01109	428125.CLOLEP_03205	7.47e-69	209.0	2C5R4@1|root,31VPY@2|Bacteria,1V8EP@1239|Firmicutes,24JPJ@186801|Clostridia,3WJKA@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
HLKFIFDC_01110	428125.CLOLEP_03206	2.67e-275	756.0	COG1196@1|root,COG1196@2|Bacteria,1UQCD@1239|Firmicutes,24AY9@186801|Clostridia,3WN2G@541000|Ruminococcaceae	186801|Clostridia	D	Plasmid recombination enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Mob_Pre
HLKFIFDC_01111	428125.CLOLEP_03207	7.66e-224	617.0	COG3598@1|root,COG3598@2|Bacteria,1UIBK@1239|Firmicutes,24K1Q@186801|Clostridia,3WGEM@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_25,Prim-Pol
HLKFIFDC_01113	428125.CLOLEP_03209	1.01e-68	208.0	2AQJ5@1|root,31FRY@2|Bacteria,1V6TG@1239|Firmicutes,24JD1@186801|Clostridia,3WJXJ@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01114	428125.CLOLEP_03210	6.21e-158	450.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,3WHJS@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
HLKFIFDC_01115	1232446.BAIE02000064_gene3615	1.58e-70	212.0	COG3070@1|root,COG3070@2|Bacteria,1V42M@1239|Firmicutes,24JNV@186801|Clostridia,26CQF@186813|unclassified Clostridiales	186801|Clostridia	K	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
HLKFIFDC_01116	1504823.CCMM01000012_gene1965	1.2e-98	288.0	2CEH6@1|root,32RZW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
HLKFIFDC_01117	658088.HMPREF0987_01846	9.3e-122	346.0	COG0617@1|root,COG0617@2|Bacteria,1V1W2@1239|Firmicutes,24FII@186801|Clostridia,27KJU@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Aminoglycoside-2''-adenylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminoglyc_resit
HLKFIFDC_01118	537007.BLAHAN_04059	2.16e-05	45.4	2EHNJ@1|root,33BEC@2|Bacteria,1VQF0@1239|Firmicutes,24V53@186801|Clostridia,3Y1V8@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01119	1121115.AXVN01000105_gene591	6.85e-113	323.0	COG3695@1|root,COG3695@2|Bacteria,1TPJI@1239|Firmicutes,249H6@186801|Clostridia,3XZ1A@572511|Blautia	186801|Clostridia	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DNA_binding_1
HLKFIFDC_01120	1121115.AXVN01000105_gene592	1.76e-160	449.0	COG1476@1|root,COG1476@2|Bacteria,1VEKB@1239|Firmicutes,24DSY@186801|Clostridia,3Y29A@572511|Blautia	186801|Clostridia	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HLKFIFDC_01121	1235799.C818_02643	4.49e-265	728.0	COG2946@1|root,COG2946@2|Bacteria,1UYFS@1239|Firmicutes,24FME@186801|Clostridia,27IW6@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Replication initiation factor	-	-	-	-	-	-	-	-	-	-	-	-	Rep_trans
HLKFIFDC_01122	411460.RUMTOR_01829	3.87e-42	137.0	2CCB2@1|root,32S7G@2|Bacteria,1VABI@1239|Firmicutes,24MZT@186801|Clostridia,3Y0CD@572511|Blautia	186801|Clostridia	L	Excisionase from transposon Tn916	-	-	-	-	-	-	-	-	-	-	-	-	Tn916-Xis
HLKFIFDC_01123	1235799.C818_02646	5.25e-279	763.0	COG0582@1|root,COG0582@2|Bacteria,1TPCB@1239|Firmicutes,2485Y@186801|Clostridia,27IJX@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_DNA,Phage_int_SAM_5,Phage_integrase
HLKFIFDC_01124	411468.CLOSCI_03087	6.78e-122	355.0	2ACJG@1|root,3125V@2|Bacteria,1V64X@1239|Firmicutes,24HPE@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01126	411468.CLOSCI_03088	4.68e-165	467.0	COG1396@1|root,COG1396@2|Bacteria,1V7ID@1239|Firmicutes,24DIG@186801|Clostridia	186801|Clostridia	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007,HTH_3
HLKFIFDC_01127	411459.RUMOBE_03331	1.94e-94	277.0	COG3695@1|root,COG3695@2|Bacteria,1TPJI@1239|Firmicutes,249H6@186801|Clostridia,3XZ1A@572511|Blautia	186801|Clostridia	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DNA_binding_1
HLKFIFDC_01128	411468.CLOSCI_03090	8.66e-96	280.0	2DQY6@1|root,339C9@2|Bacteria,1UI7Q@1239|Firmicutes,25ECW@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01129	768704.Desmer_4470	1.99e-79	247.0	29USN@1|root,30G4X@2|Bacteria,1V47A@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01130	411468.CLOSCI_03094	1.64e-48	169.0	COG3206@1|root,COG3206@2|Bacteria,1TR5K@1239|Firmicutes,24ARC@186801|Clostridia	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Mob_Pre
HLKFIFDC_01131	411468.CLOSCI_03094	4.37e-159	460.0	COG3206@1|root,COG3206@2|Bacteria,1TR5K@1239|Firmicutes,24ARC@186801|Clostridia	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Mob_Pre
HLKFIFDC_01132	471875.RUMLAC_01418	1.2e-70	213.0	2BXTH@1|root,2ZZ52@2|Bacteria,1V3TU@1239|Firmicutes,24I3V@186801|Clostridia,3WJS5@541000|Ruminococcaceae	186801|Clostridia	S	Bacterial protein of unknown function (DUF961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF961
HLKFIFDC_01133	411459.RUMOBE_02491	9.82e-84	247.0	28NIV@1|root,2ZBK5@2|Bacteria,1V1U5@1239|Firmicutes,24IAF@186801|Clostridia,3Y1IN@572511|Blautia	186801|Clostridia	S	COG NOG13239 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF961
HLKFIFDC_01134	411459.RUMOBE_02492	1.73e-128	376.0	COG1674@1|root,COG1674@2|Bacteria,1TPHE@1239|Firmicutes,249WR@186801|Clostridia,3Y1AZ@572511|Blautia	186801|Clostridia	D	COG COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	FtsK_SpoIIIE
HLKFIFDC_01135	457412.RSAG_00812	5.26e-127	374.0	28IGH@1|root,2Z8HY@2|Bacteria,1TQX2@1239|Firmicutes,249TA@186801|Clostridia,3WI6V@541000|Ruminococcaceae	186801|Clostridia	S	Conjugative transposon protein TcpC	-	-	-	-	-	-	-	-	-	-	-	-	TpcC
HLKFIFDC_01136	1256908.HMPREF0373_02452	1.43e-162	457.0	COG1396@1|root,COG1396@2|Bacteria,1VF0W@1239|Firmicutes,24R43@186801|Clostridia,25XB4@186806|Eubacteriaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HLKFIFDC_01137	411459.RUMOBE_03331	6.33e-109	313.0	COG3695@1|root,COG3695@2|Bacteria,1TPJI@1239|Firmicutes,249H6@186801|Clostridia,3XZ1A@572511|Blautia	186801|Clostridia	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DNA_binding_1
HLKFIFDC_01138	742765.HMPREF9457_03737	5.01e-80	237.0	COG1396@1|root,COG1396@2|Bacteria,1V4ZE@1239|Firmicutes,24J34@186801|Clostridia,27X28@189330|Dorea	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
HLKFIFDC_01139	471875.RUMLAC_01446	6.01e-93	272.0	COG1595@1|root,COG1595@2|Bacteria,1TSMC@1239|Firmicutes,24FTZ@186801|Clostridia,3WSS6@541000|Ruminococcaceae	186801|Clostridia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4_2
HLKFIFDC_01140	411459.RUMOBE_02513	8.9e-51	160.0	2AJW5@1|root,32RUV@2|Bacteria,1UHK2@1239|Firmicutes,24TE6@186801|Clostridia	186801|Clostridia	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_16
HLKFIFDC_01141	471875.RUMLAC_01449	1.6e-36	123.0	2DPW7@1|root,333NJ@2|Bacteria,1TUXF@1239|Firmicutes,25NXH@186801|Clostridia,3WQNR@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF3173)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3173
HLKFIFDC_01142	471875.RUMLAC_01450	7.52e-283	773.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,24EQM@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
HLKFIFDC_01144	457412.RSAG_01255	2.87e-139	417.0	COG0577@1|root,COG0577@2|Bacteria,1TRAS@1239|Firmicutes,248SQ@186801|Clostridia,3WH8W@541000|Ruminococcaceae	186801|Clostridia	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
HLKFIFDC_01145	457412.RSAG_01255	0.0	1116.0	COG0577@1|root,COG0577@2|Bacteria,1TRAS@1239|Firmicutes,248SQ@186801|Clostridia,3WH8W@541000|Ruminococcaceae	186801|Clostridia	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
HLKFIFDC_01146	457412.RSAG_01256	2.47e-156	439.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,3WG7X@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter, ATP-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HLKFIFDC_01147	457412.RSAG_01268	1.91e-190	533.0	COG0642@1|root,COG2205@2|Bacteria,1TR7T@1239|Firmicutes,24B3F@186801|Clostridia,3WRJK@541000|Ruminococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
HLKFIFDC_01148	457412.RSAG_01269	6.65e-81	244.0	COG0745@1|root,COG0745@2|Bacteria,1TQRT@1239|Firmicutes,248JM@186801|Clostridia,3WHTF@541000|Ruminococcaceae	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HLKFIFDC_01149	457412.RSAG_01269	3.48e-41	140.0	COG0745@1|root,COG0745@2|Bacteria,1TQRT@1239|Firmicutes,248JM@186801|Clostridia,3WHTF@541000|Ruminococcaceae	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HLKFIFDC_01150	742765.HMPREF9457_02460	2.21e-108	339.0	28HPA@1|root,2Z7XB@2|Bacteria,1TRBX@1239|Firmicutes,24AUG@186801|Clostridia,27W3E@189330|Dorea	186801|Clostridia	S	MobA/MobL family	-	-	-	-	-	-	-	-	-	-	-	-	MobA_MobL
HLKFIFDC_01151	1256908.HMPREF0373_01966	1.69e-192	549.0	COG5545@1|root,COG5545@2|Bacteria,1TQNX@1239|Firmicutes,2495S@186801|Clostridia,25VCP@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	VirE
HLKFIFDC_01152	742723.HMPREF9477_01326	1.7e-67	213.0	COG0358@1|root,COG0358@2|Bacteria,1UZ28@1239|Firmicutes,248N2@186801|Clostridia,27PAG@186928|unclassified Lachnospiraceae	186801|Clostridia	L	CHC2 zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-CHC2
HLKFIFDC_01153	1123075.AUDP01000004_gene796	3.78e-42	141.0	2AQJ5@1|root,31FRY@2|Bacteria,1V6TG@1239|Firmicutes,24JD1@186801|Clostridia,3WJXJ@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01154	1235793.C809_03881	1.21e-190	537.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,27IQ7@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
HLKFIFDC_01155	552396.HMPREF0863_00296	5.13e-09	54.3	2A77X@1|root,30W47@2|Bacteria,1TUDN@1239|Firmicutes,3VU8Z@526524|Erysipelotrichia	526524|Erysipelotrichia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01156	397287.C807_03059	3.91e-83	250.0	COG1396@1|root,COG1396@2|Bacteria,1V1JY@1239|Firmicutes,24HXG@186801|Clostridia,27JX0@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
HLKFIFDC_01157	411469.EUBHAL_00404	0.0	1023.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,2487F@186801|Clostridia,25V72@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
HLKFIFDC_01158	411469.EUBHAL_00402	1.84e-50	160.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	eamA	-	-	-	-	-	-	-	-	-	-	-	EamA
HLKFIFDC_01159	411469.EUBHAL_01051	4.56e-78	233.0	COG1725@1|root,COG1725@2|Bacteria,1VA2B@1239|Firmicutes,24N57@186801|Clostridia,25WY8@186806|Eubacteriaceae	186801|Clostridia	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	GntR
HLKFIFDC_01160	411469.EUBHAL_01050	9.69e-158	443.0	COG1131@1|root,COG1131@2|Bacteria,1TPUP@1239|Firmicutes,249FR@186801|Clostridia,25V9M@186806|Eubacteriaceae	186801|Clostridia	V	ABC-type multidrug transport system, ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HLKFIFDC_01161	411469.EUBHAL_01049	1.15e-174	489.0	COG1131@1|root,COG1131@2|Bacteria,1VF25@1239|Firmicutes,248Y7@186801|Clostridia,25XMF@186806|Eubacteriaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01162	411469.EUBHAL_01048	3.48e-304	830.0	COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,248IU@186801|Clostridia,25V8Z@186806|Eubacteriaceae	186801|Clostridia	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
HLKFIFDC_01163	411469.EUBHAL_01046	3e-88	260.0	2AF43@1|root,3152T@2|Bacteria,1VFMI@1239|Firmicutes,24RBI@186801|Clostridia,25WZR@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K06404	-	-	-	-	ko00000	-	-	-	SpoVAB
HLKFIFDC_01164	411469.EUBHAL_01045	3.84e-155	436.0	28PNE@1|root,2ZCB6@2|Bacteria,1V214@1239|Firmicutes,24DN2@186801|Clostridia,25WBQ@186806|Eubacteriaceae	186801|Clostridia	S	Stage V sporulation protein AA	spoVAA	-	-	ko:K06403	-	-	-	-	ko00000	-	-	-	SporV_AA
HLKFIFDC_01165	411469.EUBHAL_01044	1.72e-162	456.0	COG1191@1|root,COG1191@2|Bacteria,1TP3Q@1239|Firmicutes,2487Z@186801|Clostridia,25W1Y@186806|Eubacteriaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigF	-	-	ko:K03090,ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
HLKFIFDC_01166	411469.EUBHAL_01043	7.2e-103	298.0	COG2172@1|root,COG2172@2|Bacteria,1V6V2@1239|Firmicutes,24JPT@186801|Clostridia,25WSM@186806|Eubacteriaceae	186801|Clostridia	F	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition	spoIIAB	-	2.7.11.1	ko:K06379	-	-	-	-	ko00000,ko01000	-	-	-	HATPase_c_2
HLKFIFDC_01167	411469.EUBHAL_01042	8e-75	225.0	COG1366@1|root,COG1366@2|Bacteria,1VENG@1239|Firmicutes,24R0X@186801|Clostridia,25XEZ@186806|Eubacteriaceae	186801|Clostridia	T	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	spoIIAA	-	-	ko:K06378	-	-	-	-	ko00000	-	-	-	STAS
HLKFIFDC_01168	411469.EUBHAL_01041	0.0	920.0	COG3063@1|root,COG3063@2|Bacteria,1UY48@1239|Firmicutes,24AGF@186801|Clostridia,25VCT@186806|Eubacteriaceae	186801|Clostridia	NU	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
HLKFIFDC_01169	411489.CLOL250_02873	8.4e-05	42.4	2EGDA@1|root,33A54@2|Bacteria,1VKC8@1239|Firmicutes,24UDV@186801|Clostridia,36P6U@31979|Clostridiaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01170	411469.EUBHAL_01039	3.79e-308	840.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,25V6Z@186806|Eubacteriaceae	186801|Clostridia	H	Folylpolyglutamate synthase	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
HLKFIFDC_01171	411469.EUBHAL_01038	0.0	1748.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia,25UXK@186806|Eubacteriaceae	186801|Clostridia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
HLKFIFDC_01172	411469.EUBHAL_01037	2.23e-194	539.0	2B4WY@1|root,31XPQ@2|Bacteria,1V739@1239|Firmicutes,24D1P@186801|Clostridia,25X9K@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
HLKFIFDC_01173	411469.EUBHAL_01036	5.32e-266	728.0	28MVQ@1|root,2ZB38@2|Bacteria,1UUTH@1239|Firmicutes,24AV8@186801|Clostridia,25WAM@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01174	411469.EUBHAL_01035	0.0	2320.0	2C1EE@1|root,2Z86R@2|Bacteria,1TS39@1239|Firmicutes,24ABS@186801|Clostridia,25VE6@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	Rnd	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01175	411469.EUBHAL_01034	0.0	912.0	COG1055@1|root,COG1055@2|Bacteria,1TT1V@1239|Firmicutes,24ART@186801|Clostridia,25VHN@186806|Eubacteriaceae	186801|Clostridia	P	CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS_2
HLKFIFDC_01176	411469.EUBHAL_01032	2.07e-149	420.0	COG1896@1|root,COG1896@2|Bacteria,1V3MK@1239|Firmicutes,24IBW@186801|Clostridia,25W41@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K07023	-	-	-	-	ko00000	-	-	-	HD_3
HLKFIFDC_01177	411469.EUBHAL_01031	0.0	1296.0	COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,24CD5@186801|Clostridia	186801|Clostridia	O	Belongs to the peptidase S8 family	-	-	-	ko:K13274,ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Big_2,CW_binding_2,ChW,Peptidase_S8,SLH
HLKFIFDC_01178	411469.EUBHAL_01030	1.03e-237	653.0	COG0042@1|root,COG0042@2|Bacteria,1TRJM@1239|Firmicutes,247R5@186801|Clostridia,25V74@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
HLKFIFDC_01179	411469.EUBHAL_01029	0.0	968.0	COG2195@1|root,COG2195@2|Bacteria,1TQBS@1239|Firmicutes,24860@186801|Clostridia,25UY0@186806|Eubacteriaceae	186801|Clostridia	E	dipeptidase	pepD	-	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
HLKFIFDC_01180	411469.EUBHAL_01028	9.46e-177	491.0	COG1720@1|root,COG1720@2|Bacteria,1TSBR@1239|Firmicutes,247X5@186801|Clostridia,25W3S@186806|Eubacteriaceae	186801|Clostridia	S	Methyltransferase, YaeB family	tsaA	-	-	-	-	-	-	-	-	-	-	-	UPF0066
HLKFIFDC_01181	411469.EUBHAL_01027	1.76e-101	295.0	COG2246@1|root,COG2246@2|Bacteria,1VESW@1239|Firmicutes,24QSN@186801|Clostridia,25XGV@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
HLKFIFDC_01182	411469.EUBHAL_01025	0.0	1219.0	COG4690@1|root,COG5492@1|root,COG4690@2|Bacteria,COG5492@2|Bacteria,1TQ0F@1239|Firmicutes,248K3@186801|Clostridia,25YIC@186806|Eubacteriaceae	186801|Clostridia	E	Peptidase family C69	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C69,SLH
HLKFIFDC_01184	411469.EUBHAL_01023	1.03e-211	586.0	COG0860@1|root,COG0860@2|Bacteria,1UY5Q@1239|Firmicutes,247Y6@186801|Clostridia,25VWY@186806|Eubacteriaceae	186801|Clostridia	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,SH3_3
HLKFIFDC_01185	411469.EUBHAL_01022	1.05e-207	582.0	2DISP@1|root,3042D@2|Bacteria,1VKA2@1239|Firmicutes,24W6M@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01186	411469.EUBHAL_03264	5.41e-145	409.0	COG2801@1|root,COG2801@2|Bacteria,1TQEG@1239|Firmicutes,25B5A@186801|Clostridia	186801|Clostridia	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,HTH_28,rve,rve_2
HLKFIFDC_01187	411469.EUBHAL_02861	4.75e-304	831.0	COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,247Q3@186801|Clostridia,25V0E@186806|Eubacteriaceae	186801|Clostridia	P	Potassium uptake protein	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
HLKFIFDC_01188	411469.EUBHAL_02862	1.63e-152	428.0	COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,249C2@186801|Clostridia,25VKV@186806|Eubacteriaceae	186801|Clostridia	P	TrkA N-terminal domain protein	ktrA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
HLKFIFDC_01190	411469.EUBHAL_02864	0.0	1018.0	COG0642@1|root,COG2205@2|Bacteria,1TQHB@1239|Firmicutes,247S4@186801|Clostridia,25UXP@186806|Eubacteriaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA,KdpD
HLKFIFDC_01191	411469.EUBHAL_02865	4.83e-163	456.0	COG0745@1|root,COG0745@2|Bacteria,1UDAQ@1239|Firmicutes,249RQ@186801|Clostridia,25VEC@186806|Eubacteriaceae	186801|Clostridia	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HLKFIFDC_01192	411469.EUBHAL_02866	1.71e-210	582.0	COG0826@1|root,COG0826@2|Bacteria,1TRX5@1239|Firmicutes,24CTG@186801|Clostridia,25VZE@186806|Eubacteriaceae	186801|Clostridia	O	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01193	411469.EUBHAL_02867	6.45e-206	570.0	COG1387@1|root,COG1387@2|Bacteria,1TRKS@1239|Firmicutes,249TM@186801|Clostridia,25VDW@186806|Eubacteriaceae	186801|Clostridia	E	histidinol phosphate phosphatase, HisJ family	hisK	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
HLKFIFDC_01194	411469.EUBHAL_02868	2.63e-240	660.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,25VFF@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
HLKFIFDC_01195	411469.EUBHAL_02869	7.32e-289	789.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,25V9X@186806|Eubacteriaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	pgk	-	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
HLKFIFDC_01196	411469.EUBHAL_02870	1.82e-175	489.0	COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia,25UQW@186806|Eubacteriaceae	186801|Clostridia	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS19265	TIM
HLKFIFDC_01197	411469.EUBHAL_02871	0.0	1036.0	COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,247JG@186801|Clostridia,25V4A@186806|Eubacteriaceae	186801|Clostridia	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
HLKFIFDC_01198	411469.EUBHAL_02872	8.67e-153	432.0	COG3786@1|root,COG3786@2|Bacteria,1VA00@1239|Firmicutes,24HTX@186801|Clostridia,25XDS@186806|Eubacteriaceae	186801|Clostridia	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
HLKFIFDC_01199	411469.EUBHAL_02873	1.13e-223	614.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia,25VYS@186806|Eubacteriaceae	186801|Clostridia	J	Metallopeptidase family M24	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24,SEC-C
HLKFIFDC_01200	411469.EUBHAL_02875	6.03e-270	740.0	COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,248H1@186801|Clostridia,25WFS@186806|Eubacteriaceae	186801|Clostridia	E	Periplasmic binding protein	braC	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
HLKFIFDC_01201	411469.EUBHAL_02876	6.9e-187	522.0	COG0559@1|root,COG0559@2|Bacteria,1TR24@1239|Firmicutes,2480A@186801|Clostridia,25VFQ@186806|Eubacteriaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
HLKFIFDC_01202	411469.EUBHAL_02877	1.83e-238	658.0	COG4177@1|root,COG4177@2|Bacteria,1TPMZ@1239|Firmicutes,248WH@186801|Clostridia,25WAG@186806|Eubacteriaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	livM	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
HLKFIFDC_01203	411469.EUBHAL_02878	3.8e-174	486.0	COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,2490B@186801|Clostridia,25VQJ@186806|Eubacteriaceae	186801|Clostridia	E	Psort location CytoplasmicMembrane, score	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
HLKFIFDC_01204	411469.EUBHAL_02879	7.95e-159	446.0	COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,247PN@186801|Clostridia,25VVG@186806|Eubacteriaceae	186801|Clostridia	E	Psort location CytoplasmicMembrane, score	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
HLKFIFDC_01205	411469.EUBHAL_02880	9.53e-147	413.0	COG1102@1|root,COG1102@2|Bacteria,1V1PJ@1239|Firmicutes,24GMN@186801|Clostridia,25WQM@186806|Eubacteriaceae	186801|Clostridia	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
HLKFIFDC_01206	411469.EUBHAL_02881	3.83e-308	841.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,25URS@186806|Eubacteriaceae	186801|Clostridia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
HLKFIFDC_01207	411469.EUBHAL_02882	1.97e-266	731.0	COG1744@1|root,COG1744@2|Bacteria,1UZEP@1239|Firmicutes,25C7C@186801|Clostridia	186801|Clostridia	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
HLKFIFDC_01208	411469.EUBHAL_02884	0.0	983.0	COG3845@1|root,COG3845@2|Bacteria,1UYQA@1239|Firmicutes,24XN8@186801|Clostridia,25UYU@186806|Eubacteriaceae	186801|Clostridia	P	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
HLKFIFDC_01209	411469.EUBHAL_02885	5.27e-260	712.0	COG4603@1|root,COG4603@2|Bacteria,1TP1F@1239|Firmicutes,2494C@186801|Clostridia,25W0W@186806|Eubacteriaceae	186801|Clostridia	P	Branched-chain amino acid transport system / permease component	tsgB13	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
HLKFIFDC_01210	411469.EUBHAL_02886	8.8e-217	600.0	COG1079@1|root,COG1079@2|Bacteria,1TP8Y@1239|Firmicutes,2486N@186801|Clostridia,25WA2@186806|Eubacteriaceae	186801|Clostridia	U	Branched-chain amino acid transport system / permease component	tsgC13	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
HLKFIFDC_01211	411469.EUBHAL_02887	3.06e-299	817.0	COG1744@1|root,COG1744@2|Bacteria,1UZEP@1239|Firmicutes,25C7C@186801|Clostridia	186801|Clostridia	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
HLKFIFDC_01212	411469.EUBHAL_02888	3.46e-40	133.0	COG1314@1|root,COG1314@2|Bacteria,1VG46@1239|Firmicutes,24QMG@186801|Clostridia,25X7Y@186806|Eubacteriaceae	186801|Clostridia	U	Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
HLKFIFDC_01213	411469.EUBHAL_02889	0.0	1561.0	COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,247ZS@186801|Clostridia,25URR@186806|Eubacteriaceae	186801|Clostridia	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
HLKFIFDC_01214	411469.EUBHAL_02890	6.11e-106	306.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,24HD6@186801|Clostridia,25W1A@186806|Eubacteriaceae	186801|Clostridia	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
HLKFIFDC_01215	411469.EUBHAL_01204	4.61e-135	382.0	COG0860@1|root,COG0860@2|Bacteria,1V0RH@1239|Firmicutes,24DWG@186801|Clostridia	186801|Clostridia	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
HLKFIFDC_01216	411469.EUBHAL_01205	1.44e-275	760.0	COG4915@1|root,COG4915@2|Bacteria,1U2SU@1239|Firmicutes,24B5W@186801|Clostridia,25W62@186806|Eubacteriaceae	186801|Clostridia	S	5-bromo-4-chloroindolyl phosphate hydrolysis protein	-	-	-	-	-	-	-	-	-	-	-	-	Halogen_Hydrol
HLKFIFDC_01217	411469.EUBHAL_01206	7.52e-246	678.0	COG3853@1|root,COG3853@2|Bacteria,1TQVX@1239|Firmicutes,24A2H@186801|Clostridia,25V4B@186806|Eubacteriaceae	186801|Clostridia	P	Toxic anion resistance protein (TelA)	-	-	-	-	-	-	-	-	-	-	-	-	TelA
HLKFIFDC_01218	411469.EUBHAL_01207	6.08e-153	430.0	COG0791@1|root,COG0791@2|Bacteria,1TRKG@1239|Firmicutes,249Y4@186801|Clostridia,25W7X@186806|Eubacteriaceae	186801|Clostridia	MT	Psort location Extracellular, score	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60,SH3_3
HLKFIFDC_01219	411469.EUBHAL_01208	0.0	1946.0	COG1401@1|root,COG1401@2|Bacteria,1TPIP@1239|Firmicutes,249RD@186801|Clostridia	186801|Clostridia	V	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K07452	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	AAA_5
HLKFIFDC_01220	411469.EUBHAL_01209	2.95e-283	778.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,25V1G@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
HLKFIFDC_01221	411469.EUBHAL_01210	0.0	1148.0	COG0546@1|root,COG0673@1|root,COG0546@2|Bacteria,COG0673@2|Bacteria,1V1FQ@1239|Firmicutes,24G1U@186801|Clostridia,25WHJ@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	nt5e	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
HLKFIFDC_01222	411469.EUBHAL_01212	2.24e-170	478.0	COG0568@1|root,COG0568@2|Bacteria,1W6ZA@1239|Firmicutes,25MJC@186801|Clostridia,25Z13@186806|Eubacteriaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3
HLKFIFDC_01223	411469.EUBHAL_01213	0.0	886.0	COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,2480W@186801|Clostridia,25V6T@186806|Eubacteriaceae	186801|Clostridia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
HLKFIFDC_01224	411469.EUBHAL_01215	1.21e-267	736.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,25URK@186806|Eubacteriaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
HLKFIFDC_01225	411469.EUBHAL_01216	2.29e-185	516.0	COG2384@1|root,COG2384@2|Bacteria,1V3I4@1239|Firmicutes,24BJI@186801|Clostridia,25WR5@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	trmK	-	2.1.1.217	ko:K06967	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_18,TrmK
HLKFIFDC_01226	411469.EUBHAL_01217	2e-205	568.0	COG1387@1|root,COG1387@2|Bacteria,1TRKS@1239|Firmicutes,249TM@186801|Clostridia,25VDW@186806|Eubacteriaceae	186801|Clostridia	E	histidinol phosphate phosphatase, HisJ family	-	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
HLKFIFDC_01227	411469.EUBHAL_03171	5.09e-165	463.0	COG1145@1|root,COG1145@2|Bacteria,1TPAZ@1239|Firmicutes,249NJ@186801|Clostridia,25V1Y@186806|Eubacteriaceae	186801|Clostridia	C	4Fe-4S binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6
HLKFIFDC_01228	411469.EUBHAL_03172	1.95e-45	146.0	2DQDV@1|root,33675@2|Bacteria,1VITX@1239|Firmicutes,24S3U@186801|Clostridia,25Z8I@186806|Eubacteriaceae	186801|Clostridia	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
HLKFIFDC_01231	411469.EUBHAL_00285	7.86e-286	781.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,24855@186801|Clostridia,25V11@186806|Eubacteriaceae	186801|Clostridia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
HLKFIFDC_01235	411469.EUBHAL_01899	0.0	965.0	COG0621@1|root,COG0621@2|Bacteria,1TNYN@1239|Firmicutes,2482Y@186801|Clostridia,25V1A@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
HLKFIFDC_01236	411469.EUBHAL_01900	0.0	1701.0	COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,248GI@186801|Clostridia,25V4T@186806|Eubacteriaceae	186801|Clostridia	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
HLKFIFDC_01237	411469.EUBHAL_01901	0.0	1338.0	COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,24902@186801|Clostridia,25VTD@186806|Eubacteriaceae	186801|Clostridia	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
HLKFIFDC_01238	411469.EUBHAL_01902	5.81e-224	618.0	COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,248HB@186801|Clostridia,25UWA@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
HLKFIFDC_01239	411469.EUBHAL_01903	0.0	879.0	COG4100@1|root,COG4100@2|Bacteria,1TQ88@1239|Firmicutes,247Y4@186801|Clostridia,25UWK@186806|Eubacteriaceae	186801|Clostridia	P	Aluminum resistance protein	ynbB	-	-	-	-	-	-	-	-	-	-	-	Met_gamma_lyase
HLKFIFDC_01240	411469.EUBHAL_01904	1.07e-161	453.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,2498Z@186801|Clostridia,25WDH@186806|Eubacteriaceae	186801|Clostridia	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
HLKFIFDC_01241	411469.EUBHAL_01905	1.69e-242	667.0	COG1077@1|root,COG1077@2|Bacteria,1TPVU@1239|Firmicutes,248CM@186801|Clostridia,25VAP@186806|Eubacteriaceae	186801|Clostridia	D	Cell shape determining protein, MreB Mrl family	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
HLKFIFDC_01242	411469.EUBHAL_01906	1.6e-189	528.0	COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,249M3@186801|Clostridia,25WBY@186806|Eubacteriaceae	186801|Clostridia	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
HLKFIFDC_01243	411469.EUBHAL_01907	5.08e-114	327.0	COG2891@1|root,COG2891@2|Bacteria,1V1EJ@1239|Firmicutes,24GF4@186801|Clostridia,25W90@186806|Eubacteriaceae	186801|Clostridia	M	rod shape-determining protein MreD	mreD	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
HLKFIFDC_01244	411469.EUBHAL_01908	0.0	1875.0	COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,2480Z@186801|Clostridia,25VGU@186806|Eubacteriaceae	186801|Clostridia	M	Penicillin-binding protein, transpeptidase domain protein	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
HLKFIFDC_01245	411469.EUBHAL_01909	2.01e-163	459.0	COG0850@1|root,COG0850@2|Bacteria,1VAPC@1239|Firmicutes,24MV1@186801|Clostridia,25WSB@186806|Eubacteriaceae	186801|Clostridia	D	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization	minC	-	-	ko:K03610	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinC_C
HLKFIFDC_01246	411469.EUBHAL_01910	1.95e-177	495.0	COG2894@1|root,COG2894@2|Bacteria,1TP6P@1239|Firmicutes,249BB@186801|Clostridia,25VVP@186806|Eubacteriaceae	186801|Clostridia	D	Belongs to the ParA family	minD	-	-	ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
HLKFIFDC_01247	411469.EUBHAL_01911	7.29e-60	184.0	COG0851@1|root,COG0851@2|Bacteria,1VFST@1239|Firmicutes,24QT6@186801|Clostridia,25WUI@186806|Eubacteriaceae	186801|Clostridia	D	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell	minE	-	-	ko:K03608	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinE
HLKFIFDC_01248	411469.EUBHAL_01912	2.59e-256	704.0	COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,247WS@186801|Clostridia,25VRW@186806|Eubacteriaceae	186801|Clostridia	D	Belongs to the SEDS family	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
HLKFIFDC_01249	411469.EUBHAL_01913	1.88e-92	270.0	COG1803@1|root,COG1803@2|Bacteria,1V3KQ@1239|Firmicutes,24FUQ@186801|Clostridia,25WBS@186806|Eubacteriaceae	186801|Clostridia	G	methylglyoxal synthase	mgsA	-	4.2.3.3	ko:K01734	ko00640,ko01120,map00640,map01120	-	R01016	RC00424	ko00000,ko00001,ko01000	-	-	-	MGS
HLKFIFDC_01250	411469.EUBHAL_01914	2.03e-224	619.0	COG1686@1|root,COG1686@2|Bacteria,1TU06@1239|Firmicutes,25B23@186801|Clostridia,25V87@186806|Eubacteriaceae	186801|Clostridia	M	Beta-lactamase enzyme family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
HLKFIFDC_01251	411469.EUBHAL_01915	1.11e-92	271.0	COG0593@1|root,COG0593@2|Bacteria,1VAFE@1239|Firmicutes,25E3U@186801|Clostridia,25ZUI@186806|Eubacteriaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01252	411469.EUBHAL_01916	3.04e-232	638.0	COG1242@1|root,COG1242@2|Bacteria,1TQ57@1239|Firmicutes,247U3@186801|Clostridia,25V7W@186806|Eubacteriaceae	186801|Clostridia	S	radical SAM protein, TIGR01212 family	-	-	-	ko:K07139	-	-	-	-	ko00000	-	-	-	Radical_SAM,Radical_SAM_C
HLKFIFDC_01253	411469.EUBHAL_01917	0.0	875.0	2DBI9@1|root,2Z9F5@2|Bacteria,1UI10@1239|Firmicutes,25E9Z@186801|Clostridia,25VX9@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01254	411469.EUBHAL_01918	4.48e-162	454.0	COG0325@1|root,COG0325@2|Bacteria,1TRDN@1239|Firmicutes,248R6@186801|Clostridia,25VJK@186806|Eubacteriaceae	186801|Clostridia	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	ylmE	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
HLKFIFDC_01255	411469.EUBHAL_01919	3.86e-105	305.0	COG1799@1|root,COG1799@2|Bacteria,1VER3@1239|Firmicutes,24I9Y@186801|Clostridia,25WZ4@186806|Eubacteriaceae	186801|Clostridia	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	-	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
HLKFIFDC_01256	411469.EUBHAL_01920	3.83e-256	702.0	COG0337@1|root,COG0337@2|Bacteria,1TPKZ@1239|Firmicutes,248H4@186801|Clostridia,25VI1@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
HLKFIFDC_01257	411469.EUBHAL_01921	6.23e-113	324.0	COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,24QPP@186801|Clostridia,25WRT@186806|Eubacteriaceae	186801|Clostridia	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
HLKFIFDC_01258	411469.EUBHAL_01922	1.76e-233	642.0	COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,247Y2@186801|Clostridia,25VQR@186806|Eubacteriaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
HLKFIFDC_01259	411469.EUBHAL_01923	1.91e-55	174.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,25WWJ@186806|Eubacteriaceae	186801|Clostridia	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
HLKFIFDC_01260	411469.EUBHAL_01924	5.9e-152	427.0	COG0457@1|root,COG0457@2|Bacteria,1V4J9@1239|Firmicutes,24VUT@186801|Clostridia	186801|Clostridia	S	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_8
HLKFIFDC_01261	411469.EUBHAL_01925	3.56e-56	174.0	COG1925@1|root,COG1925@2|Bacteria,1VA23@1239|Firmicutes,24N32@186801|Clostridia,25XB7@186806|Eubacteriaceae	186801|Clostridia	G	PTS HPr component phosphorylation site	ptsH	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
HLKFIFDC_01262	411469.EUBHAL_01926	0.0	1076.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,25UYQ@186806|Eubacteriaceae	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
HLKFIFDC_01263	411469.EUBHAL_01927	0.0	1320.0	COG0210@1|root,COG0210@2|Bacteria,1TPVG@1239|Firmicutes,2484I@186801|Clostridia,25UV4@186806|Eubacteriaceae	186801|Clostridia	L	DNA helicase	yjcD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
HLKFIFDC_01264	411469.EUBHAL_01928	1.67e-183	511.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,249KK@186801|Clostridia,25VRX@186806|Eubacteriaceae	186801|Clostridia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
HLKFIFDC_01265	411469.EUBHAL_01929	3.35e-131	372.0	COG2263@1|root,COG2263@2|Bacteria,1UK73@1239|Firmicutes,25FNT@186801|Clostridia,25ZK4@186806|Eubacteriaceae	186801|Clostridia	J	Putative rRNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7,rRNA_methylase
HLKFIFDC_01266	411469.EUBHAL_01930	4.76e-182	507.0	COG0543@1|root,COG0543@2|Bacteria,1TQ5D@1239|Firmicutes,24AY2@186801|Clostridia,25V0Z@186806|Eubacteriaceae	186801|Clostridia	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
HLKFIFDC_01267	411469.EUBHAL_01931	4.09e-218	601.0	COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,248CQ@186801|Clostridia,25USG@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
HLKFIFDC_01268	411469.EUBHAL_01932	2.47e-159	447.0	COG0461@1|root,COG0461@2|Bacteria,1TREW@1239|Firmicutes,248WM@186801|Clostridia,25V0N@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
HLKFIFDC_01269	1235798.C817_02915	6.38e-08	50.8	2DRBT@1|root,33B4Z@2|Bacteria,1VMZQ@1239|Firmicutes,24UIT@186801|Clostridia,27VXW@189330|Dorea	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01270	411469.EUBHAL_01935	1.9e-105	305.0	COG4767@1|root,COG4767@2|Bacteria,1VAH6@1239|Firmicutes,24MQR@186801|Clostridia,25XKJ@186806|Eubacteriaceae	186801|Clostridia	V	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
HLKFIFDC_01272	411469.EUBHAL_01937	0.0	1403.0	COG2309@1|root,COG2309@2|Bacteria,1TSPE@1239|Firmicutes,24A6S@186801|Clostridia,25UZY@186806|Eubacteriaceae	186801|Clostridia	E	Leucyl aminopeptidase (Aminopeptidase T)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M29
HLKFIFDC_01273	411469.EUBHAL_01938	4.96e-308	839.0	COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,247V2@186801|Clostridia,25VA4@186806|Eubacteriaceae	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
HLKFIFDC_01274	411469.EUBHAL_01939	3.14e-226	622.0	COG0284@1|root,COG0284@2|Bacteria,1TQ7P@1239|Firmicutes,247SZ@186801|Clostridia,25VM9@186806|Eubacteriaceae	186801|Clostridia	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS17585	OMPdecase
HLKFIFDC_01275	411469.EUBHAL_01940	4.52e-112	322.0	COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,24HCB@186801|Clostridia,25WPU@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
HLKFIFDC_01276	411469.EUBHAL_01941	6.51e-247	677.0	COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,248BT@186801|Clostridia,25UWB@186806|Eubacteriaceae	186801|Clostridia	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
HLKFIFDC_01277	411469.EUBHAL_01942	1.15e-144	408.0	COG0299@1|root,COG0299@2|Bacteria,1V3RJ@1239|Firmicutes,249JC@186801|Clostridia,25VE7@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS04225	Formyl_trans_N
HLKFIFDC_01278	411469.EUBHAL_01943	1.44e-313	853.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,25E76@186801|Clostridia,25V1T@186806|Eubacteriaceae	186801|Clostridia	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
HLKFIFDC_01279	411469.EUBHAL_01944	9.22e-152	428.0	COG1296@1|root,COG1296@2|Bacteria,1TSXD@1239|Firmicutes,24CRN@186801|Clostridia,25W54@186806|Eubacteriaceae	186801|Clostridia	E	AzlC protein	ygaZ	-	-	-	-	-	-	-	-	-	-	-	AzlC
HLKFIFDC_01280	411469.EUBHAL_01945	7.57e-55	172.0	COG4392@1|root,COG4392@2|Bacteria,1VAKN@1239|Firmicutes,24N0I@186801|Clostridia,25ZWZ@186806|Eubacteriaceae	186801|Clostridia	S	Branched-chain amino acid transport protein (AzlD)	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
HLKFIFDC_01281	411469.EUBHAL_02918	3.98e-292	807.0	COG1672@1|root,COG1672@2|Bacteria,1TQQ5@1239|Firmicutes,24918@186801|Clostridia,25VWZ@186806|Eubacteriaceae	186801|Clostridia	S	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
HLKFIFDC_01282	411469.EUBHAL_01947	0.0	2927.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1TPU5@1239|Firmicutes,2481F@186801|Clostridia,25VEA@186806|Eubacteriaceae	186801|Clostridia	I	CoA-substrate-specific enzyme activase	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
HLKFIFDC_01283	411469.EUBHAL_01948	0.0	1123.0	COG1069@1|root,COG1069@2|Bacteria,1TP8T@1239|Firmicutes,248QY@186801|Clostridia,25VIH@186806|Eubacteriaceae	186801|Clostridia	H	Belongs to the ribulokinase family	araB	-	2.7.1.16	ko:K00853	ko00040,ko01100,map00040,map01100	-	R01526,R02439	RC00002,RC00538	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
HLKFIFDC_01284	411469.EUBHAL_01949	0.0	884.0	COG0371@1|root,COG0371@2|Bacteria,1TR6W@1239|Firmicutes,25MU6@186801|Clostridia,25WIT@186806|Eubacteriaceae	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	-	-	1.1.1.261	ko:K00096	ko00564,map00564	-	R05679,R05680	RC00029	ko00000,ko00001,ko01000	-	-	-	Fe-ADH_2
HLKFIFDC_01285	411469.EUBHAL_01950	4.93e-286	782.0	COG1609@1|root,COG1609@2|Bacteria,1UYY5@1239|Firmicutes,24C8C@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
HLKFIFDC_01286	411469.EUBHAL_01951	1.27e-110	318.0	COG1607@1|root,COG1607@2|Bacteria,1V3S2@1239|Firmicutes,24JIT@186801|Clostridia,25Z21@186806|Eubacteriaceae	186801|Clostridia	I	Thioesterase superfamily	yciA	-	-	-	-	-	-	-	-	-	-	-	4HBT
HLKFIFDC_01287	411469.EUBHAL_01953	0.0	942.0	COG1620@1|root,COG1620@2|Bacteria,1TQNM@1239|Firmicutes,2482V@186801|Clostridia,25VC4@186806|Eubacteriaceae	186801|Clostridia	C	L-lactate permease	lctP	-	-	ko:K03303	-	-	-	-	ko00000,ko02000	2.A.14	-	-	Lactate_perm
HLKFIFDC_01288	411469.EUBHAL_01954	0.0	919.0	COG0277@1|root,COG0277@2|Bacteria,1TPBC@1239|Firmicutes,24A99@186801|Clostridia,25VPQ@186806|Eubacteriaceae	186801|Clostridia	C	glycolate oxidase, subunit GlcD	glcD	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
HLKFIFDC_01289	411469.EUBHAL_01955	3.27e-187	520.0	COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,25UTI@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
HLKFIFDC_01290	411469.EUBHAL_01956	1.16e-241	664.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,25UTQ@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	etfA	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016627,GO:0016628,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363	1.3.1.108	ko:K03522,ko:K22432	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	ETF,ETF_alpha,Fer4
HLKFIFDC_01291	411469.EUBHAL_01957	3.51e-273	747.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,25USM@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	bcd	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HLKFIFDC_01292	411469.EUBHAL_01958	7.1e-311	847.0	COG3875@1|root,COG3875@2|Bacteria,1TQ1C@1239|Firmicutes,247PH@186801|Clostridia,25V9P@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	5.1.2.1	ko:K22373	ko00620,map00620	-	R01450	RC00519	ko00000,ko00001,ko01000	-	-	-	DUF2088
HLKFIFDC_01293	411469.EUBHAL_01959	8.3e-171	477.0	COG2186@1|root,COG2186@2|Bacteria,1V2TU@1239|Firmicutes,24GA8@186801|Clostridia,25VX8@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
HLKFIFDC_01294	411469.EUBHAL_01960	9.17e-54	168.0	COG1609@1|root,COG1609@2|Bacteria,1VADF@1239|Firmicutes,24MXI@186801|Clostridia,25X1K@186806|Eubacteriaceae	186801|Clostridia	K	sporulation transcriptional regulator SpoIIID	spoIIID	-	-	ko:K06283	-	-	-	-	ko00000,ko03000	-	-	-	SpoIIID
HLKFIFDC_01295	411469.EUBHAL_01963	2.75e-101	293.0	COG1762@1|root,COG1762@2|Bacteria,1UVGM@1239|Firmicutes,25NTI@186801|Clostridia,25Z34@186806|Eubacteriaceae	186801|Clostridia	H	PTS system, fructose-specific IIA component K02768	-	-	-	-	-	-	-	-	-	-	-	-	PTS_EIIA_2
HLKFIFDC_01296	411469.EUBHAL_01965	8.44e-213	601.0	COG1299@1|root,COG1299@2|Bacteria,1TPKU@1239|Firmicutes,248V6@186801|Clostridia,25VG4@186806|Eubacteriaceae	186801|Clostridia	G	Psort location CytoplasmicMembrane, score	-	-	2.7.1.191	ko:K02793,ko:K02794,ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
HLKFIFDC_01297	411469.EUBHAL_01966	0.0	1216.0	COG1762@1|root,COG3711@1|root,COG1762@2|Bacteria,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,248PT@186801|Clostridia	186801|Clostridia	GKT	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	-	-	-	ko:K02538	-	-	-	-	ko00000,ko03000	-	-	-	HTH_11,Mga,PRD,PTS_EIIA_2
HLKFIFDC_01298	411469.EUBHAL_01967	3.53e-229	632.0	COG2893@1|root,COG3444@1|root,COG2893@2|Bacteria,COG3444@2|Bacteria,1TQJ4@1239|Firmicutes,24GRK@186801|Clostridia,25XKT@186806|Eubacteriaceae	186801|Clostridia	G	Psort location Cytoplasmic, score 9.98	-	-	2.7.1.191	ko:K02745,ko:K02793,ko:K02794	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	M00276,M00277	R02630,R08366	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1,4.A.6.1.4	-	-	PTSIIB_sorb
HLKFIFDC_01299	411469.EUBHAL_01968	7.3e-155	438.0	COG3715@1|root,COG3715@2|Bacteria,1TPKK@1239|Firmicutes,25M5N@186801|Clostridia,25XYY@186806|Eubacteriaceae	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.6.1	-	-	EII-Sor
HLKFIFDC_01300	411469.EUBHAL_01969	1.35e-209	580.0	COG3716@1|root,COG3716@2|Bacteria,1TQA3@1239|Firmicutes,24A0K@186801|Clostridia,25WYQ@186806|Eubacteriaceae	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K02795,ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.6.1	-	-	EII-Sor,EIID-AGA
HLKFIFDC_01301	411469.EUBHAL_01970	8.65e-81	239.0	COG4687@1|root,COG4687@2|Bacteria,1V6KV@1239|Firmicutes,24IA4@186801|Clostridia	186801|Clostridia	S	hmm pf06115	manO	-	-	-	-	-	-	-	-	-	-	-	DUF956
HLKFIFDC_01302	411469.EUBHAL_01971	1.89e-226	624.0	COG1482@1|root,COG1482@2|Bacteria,1V0PH@1239|Firmicutes,25EPT@186801|Clostridia,25VNC@186806|Eubacteriaceae	186801|Clostridia	G	Cytoplasmic, score 8.87	manA	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase,PMI_typeI
HLKFIFDC_01303	658655.HMPREF0988_00635	1.7e-55	185.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1URF2@1239|Firmicutes,24BBP@186801|Clostridia,27K82@186928|unclassified Lachnospiraceae	186801|Clostridia	T	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC,Response_reg
HLKFIFDC_01304	180332.JTGN01000005_gene2903	3.05e-73	249.0	COG2972@1|root,COG2972@2|Bacteria,1U6WN@1239|Firmicutes,24CTB@186801|Clostridia	186801|Clostridia	T	K07718 two-component system, sensor histidine kinase YesM	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,His_kinase
HLKFIFDC_01305	180332.JTGN01000005_gene2902	5.98e-153	451.0	COG1653@1|root,COG1653@2|Bacteria,1TPWV@1239|Firmicutes,24AWQ@186801|Clostridia	186801|Clostridia	G	solute-binding protein	-	-	-	ko:K17318	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	DUF3502,SBP_bac_8
HLKFIFDC_01306	411469.EUBHAL_00265	3.24e-299	839.0	COG1231@1|root,COG5492@1|root,COG1231@2|Bacteria,COG5492@2|Bacteria,1VUQN@1239|Firmicutes,24CDA@186801|Clostridia,25XH0@186806|Eubacteriaceae	186801|Clostridia	N	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF4430,F5_F8_type_C,FIVAR,Flg_new,RHS_repeat,SH3_3,SLH,fn3
HLKFIFDC_01307	1211844.CBLM010000095_gene49	7.15e-43	172.0	COG0683@1|root,COG4412@1|root,COG0683@2|Bacteria,COG4412@2|Bacteria,1V38C@1239|Firmicutes,3VSZQ@526524|Erysipelotrichia	526524|Erysipelotrichia	N	M6 family metalloprotease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,ChW,Glug
HLKFIFDC_01308	1280664.AUIX01000039_gene2391	1.96e-17	93.2	COG3209@1|root,COG3210@1|root,COG3266@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,COG3266@2|Bacteria,1V1ZH@1239|Firmicutes,24GIV@186801|Clostridia,4BWZF@830|Butyrivibrio	186801|Clostridia	U	Leucine rich repeats (6 copies)	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
HLKFIFDC_01309	411469.EUBHAL_01973	0.0	903.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,24946@186801|Clostridia,25VN2@186806|Eubacteriaceae	186801|Clostridia	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
HLKFIFDC_01310	411469.EUBHAL_01974	2.37e-134	380.0	COG0512@1|root,COG0512@2|Bacteria,1TT9R@1239|Firmicutes,24FR0@186801|Clostridia,25VZ2@186806|Eubacteriaceae	186801|Clostridia	EH	Peptidase C26	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
HLKFIFDC_01311	411469.EUBHAL_01975	1.49e-180	503.0	COG0134@1|root,COG0134@2|Bacteria,1TR94@1239|Firmicutes,249ZY@186801|Clostridia,25UVS@186806|Eubacteriaceae	186801|Clostridia	E	Belongs to the TrpC family	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
HLKFIFDC_01312	411469.EUBHAL_01976	1.45e-161	452.0	COG0135@1|root,COG0135@2|Bacteria,1V6Y0@1239|Firmicutes,24HBQ@186801|Clostridia,25WH6@186806|Eubacteriaceae	186801|Clostridia	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
HLKFIFDC_01313	411469.EUBHAL_01977	3.55e-278	761.0	COG0133@1|root,COG0133@2|Bacteria,1TPI3@1239|Firmicutes,24881@186801|Clostridia,25VIZ@186806|Eubacteriaceae	186801|Clostridia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20,5.3.1.24	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722,R03509	RC00209,RC00210,RC00700,RC00701,RC00945,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,PRAI
HLKFIFDC_01314	411469.EUBHAL_01978	2.27e-176	493.0	COG0159@1|root,COG0159@2|Bacteria,1TPXA@1239|Firmicutes,248M2@186801|Clostridia,25VB7@186806|Eubacteriaceae	186801|Clostridia	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
HLKFIFDC_01315	411469.EUBHAL_00036	2.57e-104	302.0	COG2606@1|root,COG2606@2|Bacteria,1V6JF@1239|Firmicutes,24I4E@186801|Clostridia,25WMS@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily	ybaK	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
HLKFIFDC_01316	411469.EUBHAL_00038	0.0	907.0	COG4145@1|root,COG4145@2|Bacteria,1UJ00@1239|Firmicutes,25F28@186801|Clostridia,25VC3@186806|Eubacteriaceae	186801|Clostridia	H	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	panF	-	-	ko:K11928,ko:K14392	-	-	-	-	ko00000,ko02000	2.A.21.1,2.A.21.2	-	-	SSF
HLKFIFDC_01317	411469.EUBHAL_00039	1.49e-58	181.0	2E3UX@1|root,32YS7@2|Bacteria,1VIM3@1239|Firmicutes,24THX@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF997)	-	-	-	-	-	-	-	-	-	-	-	-	DUF997
HLKFIFDC_01318	1121115.AXVN01000017_gene244	3.33e-274	765.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,247KA@186801|Clostridia,3Y18R@572511|Blautia	186801|Clostridia	NU	Type II secretion system (T2SS), protein E, N-terminal domain	xcpR	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
HLKFIFDC_01319	1121115.AXVN01000017_gene243	2.51e-193	543.0	COG2805@1|root,COG2805@2|Bacteria,1TQ5F@1239|Firmicutes,249H9@186801|Clostridia,3XYY6@572511|Blautia	186801|Clostridia	NU	Type II/IV secretion system protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
HLKFIFDC_01320	1121115.AXVN01000017_gene242	1.11e-186	530.0	COG1459@1|root,COG1459@2|Bacteria,1TQRZ@1239|Firmicutes,249FV@186801|Clostridia,3Y1N8@572511|Blautia	186801|Clostridia	NU	Type II secretion system (T2SS), protein F	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
HLKFIFDC_01322	1121115.AXVN01000017_gene240	1.28e-26	105.0	COG4968@1|root,COG4968@2|Bacteria,1VD7G@1239|Firmicutes,25FI2@186801|Clostridia,3Y0V4@572511|Blautia	186801|Clostridia	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
HLKFIFDC_01323	1121115.AXVN01000017_gene239	2.35e-81	246.0	COG1989@1|root,COG1989@2|Bacteria,1TQY4@1239|Firmicutes,24HC0@186801|Clostridia,3Y0V5@572511|Blautia	186801|Clostridia	NOU	Type IV leader peptidase family	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
HLKFIFDC_01324	1121115.AXVN01000017_gene238	2.65e-167	492.0	COG4972@1|root,COG4972@2|Bacteria,1V3TN@1239|Firmicutes,24ASH@186801|Clostridia	186801|Clostridia	NU	Type IV pilus assembly protein PilM	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2,PilN
HLKFIFDC_01325	1410632.JHWW01000009_gene2462	1.37e-05	53.1	29Y5S@1|root,31E01@2|Bacteria,1V6MG@1239|Firmicutes,258CY@186801|Clostridia,27JVB@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01326	1121115.AXVN01000017_gene236	1.77e-131	401.0	COG4967@1|root,COG4967@2|Bacteria,1VKH2@1239|Firmicutes,24UHG@186801|Clostridia	186801|Clostridia	NU	type IV pilus modification protein PilV	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
HLKFIFDC_01327	1121115.AXVN01000017_gene235	2.26e-225	664.0	2EAGJ@1|root,334JU@2|Bacteria,1VH9K@1239|Firmicutes,24IKS@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01328	1121115.AXVN01000017_gene234	1.31e-35	132.0	COG4970@1|root,COG4970@2|Bacteria	2|Bacteria	NU	protein transport across the cell outer membrane	ppdA	-	-	ko:K02679,ko:K08084,ko:K08085	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
HLKFIFDC_01329	1121115.AXVN01000017_gene233	2.36e-15	82.8	COG2165@1|root,COG2165@2|Bacteria,1W06U@1239|Firmicutes	1239|Firmicutes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
HLKFIFDC_01330	1121115.AXVN01000017_gene232	1.75e-277	871.0	COG5492@1|root,COG5492@2|Bacteria,1TT7E@1239|Firmicutes,24J1K@186801|Clostridia	186801|Clostridia	N	Domain of unknown function (DUF5057)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5057
HLKFIFDC_01331	511680.BUTYVIB_00432	3.67e-210	589.0	COG1106@1|root,COG1106@2|Bacteria,1TSBY@1239|Firmicutes,249DS@186801|Clostridia,4BZF1@830|Butyrivibrio	186801|Clostridia	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K06926	-	-	-	-	ko00000	-	-	-	AAA_21
HLKFIFDC_01332	511680.BUTYVIB_00431	5.29e-108	317.0	2DMNB@1|root,32SNM@2|Bacteria,1VB2J@1239|Firmicutes,25CZZ@186801|Clostridia,4BYU6@830|Butyrivibrio	186801|Clostridia	S	RloB-like protein	-	-	-	-	-	-	-	-	-	-	-	-	RloB
HLKFIFDC_01333	411469.EUBHAL_00040	7.84e-194	540.0	COG2017@1|root,COG2017@2|Bacteria,1U26T@1239|Firmicutes,24AQ8@186801|Clostridia,25W6R@186806|Eubacteriaceae	186801|Clostridia	G	Aldose 1-epimerase	lacX	-	-	-	-	-	-	-	-	-	-	-	Aldose_epim
HLKFIFDC_01334	411469.EUBHAL_00041	6.25e-230	644.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	3.2.1.8	ko:K01181,ko:K02027,ko:K17315,ko:K17318	ko02010,map02010	M00207,M00603,M00605	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1,3.A.1.1.24,3.A.1.1.29,3.A.1.1.30,3.A.1.1.9	-	-	CBM_4_9,Cu_amine_oxidN1,Flg_new,Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,SBP_bac_1
HLKFIFDC_01336	411469.EUBHAL_02044	1.06e-193	538.0	COG2201@1|root,COG2201@2|Bacteria,1VQS3@1239|Firmicutes,25E3X@186801|Clostridia,25VY0@186806|Eubacteriaceae	186801|Clostridia	NT	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process	-	-	-	ko:K03413,ko:K07699	ko02020,ko02024,ko02030,map02020,map02024,map02030	M00485,M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg,Spo0A_C
HLKFIFDC_01337	411469.EUBHAL_02045	1.5e-190	529.0	COG2201@1|root,COG2201@2|Bacteria,1VQS3@1239|Firmicutes,25E3X@186801|Clostridia,25VY0@186806|Eubacteriaceae	186801|Clostridia	NT	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process	spo0A	-	-	ko:K03413,ko:K07699	ko02020,ko02024,ko02030,map02020,map02024,map02030	M00485,M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg,Spo0A_C
HLKFIFDC_01338	411469.EUBHAL_01177	0.0	952.0	COG0591@1|root,COG0591@2|Bacteria,1TPVE@1239|Firmicutes,248NQ@186801|Clostridia,25UVQ@186806|Eubacteriaceae	186801|Clostridia	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307,ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21,2.A.21.2	-	-	SSF
HLKFIFDC_01339	411469.EUBHAL_01176	7.04e-218	601.0	COG0535@1|root,COG0535@2|Bacteria,1UZQ5@1239|Firmicutes,24AC1@186801|Clostridia,25ZA6@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01340	411469.EUBHAL_01175	0.0	1118.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248JC@186801|Clostridia,25UTE@186806|Eubacteriaceae	186801|Clostridia	IQ	AMP-binding enzyme C-terminal domain	lcfB	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
HLKFIFDC_01341	411469.EUBHAL_01174	2.16e-291	795.0	COG0436@1|root,COG0436@2|Bacteria,1TP36@1239|Firmicutes,248ZV@186801|Clostridia,25VQ3@186806|Eubacteriaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	yhdR	-	2.6.1.1	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
HLKFIFDC_01342	411469.EUBHAL_01173	3.34e-208	575.0	COG2159@1|root,COG2159@2|Bacteria,1TRU0@1239|Firmicutes,248VZ@186801|Clostridia,25W8X@186806|Eubacteriaceae	186801|Clostridia	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
HLKFIFDC_01343	411469.EUBHAL_01171	0.0	1044.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	2.4.1.10,3.5.1.28	ko:K00692,ko:K01448,ko:K13730	ko00500,ko01100,ko01503,ko02020,ko05100,map00500,map01100,map01503,map02020,map05100	M00727	R04112,R05140	RC00064,RC00077,RC00141	ko00000,ko00001,ko00002,ko01000,ko01003,ko01011,ko03036	-	GH68	-	Big_2,CW_binding_2,ChW,LRR_4,LRR_5,fn3
HLKFIFDC_01344	411469.EUBHAL_01170	6.52e-31	120.0	2DBD7@1|root,2Z8II@2|Bacteria,1UZG0@1239|Firmicutes,249JD@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HLKFIFDC_01345	411469.EUBHAL_01170	0.0	961.0	2DBD7@1|root,2Z8II@2|Bacteria,1UZG0@1239|Firmicutes,249JD@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HLKFIFDC_01346	411469.EUBHAL_01169	0.0	882.0	COG1541@1|root,COG1541@2|Bacteria,1TQA1@1239|Firmicutes,248G9@186801|Clostridia,25VPD@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	paaK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
HLKFIFDC_01347	411469.EUBHAL_01168	3.78e-132	375.0	COG1014@1|root,COG1014@2|Bacteria,1V1DT@1239|Firmicutes,24HIC@186801|Clostridia,25VMY@186806|Eubacteriaceae	186801|Clostridia	C	indolepyruvate ferredoxin oxidoreductase, beta subunit	iorB	-	1.2.7.8	ko:K00180	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR
HLKFIFDC_01348	411469.EUBHAL_01167	0.0	1158.0	COG4231@1|root,COG4231@2|Bacteria,1TNY3@1239|Firmicutes,247U1@186801|Clostridia,25UZ3@186806|Eubacteriaceae	186801|Clostridia	C	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates	iorA	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,POR_N,TPP_enzyme_C
HLKFIFDC_01349	411469.EUBHAL_01166	1.36e-66	202.0	COG4496@1|root,COG4496@2|Bacteria,1VA04@1239|Firmicutes,24S4A@186801|Clostridia	186801|Clostridia	S	Trp repressor protein	-	-	-	-	-	-	-	-	-	-	-	-	Trp_repressor
HLKFIFDC_01350	411469.EUBHAL_01165	4.36e-109	315.0	COG0671@1|root,COG0671@2|Bacteria,1VB2R@1239|Firmicutes,24MQ9@186801|Clostridia,25X1V@186806|Eubacteriaceae	186801|Clostridia	I	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
HLKFIFDC_01351	411469.EUBHAL_01687	0.0	1214.0	COG0539@1|root,COG0761@1|root,COG0539@2|Bacteria,COG0761@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia,25UQX@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,S1
HLKFIFDC_01352	411469.EUBHAL_01686	4.3e-151	425.0	COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,24HEF@186801|Clostridia,25W10@186806|Eubacteriaceae	186801|Clostridia	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
HLKFIFDC_01353	411469.EUBHAL_01685	4e-298	813.0	COG2081@1|root,COG2081@2|Bacteria,1TQ6E@1239|Firmicutes,247S5@186801|Clostridia,25VHS@186806|Eubacteriaceae	186801|Clostridia	S	Flavoprotein family	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
HLKFIFDC_01354	411469.EUBHAL_01684	3.55e-197	548.0	COG1737@1|root,COG1737@2|Bacteria,1TP7H@1239|Firmicutes,248ZD@186801|Clostridia,25V47@186806|Eubacteriaceae	186801|Clostridia	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
HLKFIFDC_01355	411469.EUBHAL_01682	2.04e-129	367.0	COG0503@1|root,COG0503@2|Bacteria,1V1BV@1239|Firmicutes,24HGX@186801|Clostridia,25W4A@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
HLKFIFDC_01356	411469.EUBHAL_01681	1.64e-203	563.0	COG0561@1|root,COG0561@2|Bacteria,1U3W2@1239|Firmicutes,2486H@186801|Clostridia,25WWV@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
HLKFIFDC_01357	411469.EUBHAL_01680	0.0	1169.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,247NU@186801|Clostridia,25V6B@186806|Eubacteriaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
HLKFIFDC_01358	411469.EUBHAL_01679	0.0	934.0	COG0641@1|root,COG0641@2|Bacteria,1TQPS@1239|Firmicutes,248DD@186801|Clostridia,25UU0@186806|Eubacteriaceae	186801|Clostridia	C	Six-Cys-in-45 modification radical SAM protein	scfB	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
HLKFIFDC_01360	411469.EUBHAL_01677	1.51e-82	244.0	2E3KV@1|root,32YJ5@2|Bacteria,1VEHD@1239|Firmicutes,24RP3@186801|Clostridia,25X93@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF3792)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3792
HLKFIFDC_01361	411469.EUBHAL_01676	1.35e-57	179.0	COG1862@1|root,COG1862@2|Bacteria,1VEMC@1239|Firmicutes,24MMT@186801|Clostridia,25WYU@186806|Eubacteriaceae	186801|Clostridia	U	Preprotein translocase, YajC subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
HLKFIFDC_01362	411469.EUBHAL_01675	1.41e-288	786.0	COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,247NJ@186801|Clostridia,25VIT@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
HLKFIFDC_01363	411469.EUBHAL_01674	3.79e-251	691.0	COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,24998@186801|Clostridia,25URP@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
HLKFIFDC_01364	411469.EUBHAL_01673	1.05e-169	474.0	COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,249VK@186801|Clostridia,25VA3@186806|Eubacteriaceae	186801|Clostridia	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
HLKFIFDC_01365	411469.EUBHAL_01857	0.0	866.0	COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,2481N@186801|Clostridia,25VMW@186806|Eubacteriaceae	186801|Clostridia	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
HLKFIFDC_01366	411469.EUBHAL_01855	1.19e-194	540.0	COG1737@1|root,COG1737@2|Bacteria,1TR5E@1239|Firmicutes,247Z7@186801|Clostridia,25VC6@186806|Eubacteriaceae	186801|Clostridia	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
HLKFIFDC_01367	411469.EUBHAL_01854	3.25e-158	444.0	COG3010@1|root,COG3010@2|Bacteria,1TSR7@1239|Firmicutes,24AVB@186801|Clostridia,25VTY@186806|Eubacteriaceae	186801|Clostridia	G	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)	nanE	-	5.1.3.9	ko:K01788	ko00520,map00520	-	R02087	RC00290	ko00000,ko00001,ko01000	-	-	-	NanE
HLKFIFDC_01368	411469.EUBHAL_01853	6.9e-176	489.0	COG0363@1|root,COG0363@2|Bacteria,1TP10@1239|Firmicutes,248HK@186801|Clostridia,25VFM@186806|Eubacteriaceae	186801|Clostridia	G	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
HLKFIFDC_01369	411469.EUBHAL_01852	7.46e-259	709.0	COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,248RC@186801|Clostridia,25V0U@186806|Eubacteriaceae	186801|Clostridia	J	Psort location Cytoplasmic, score	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
HLKFIFDC_01371	411469.EUBHAL_01850	4.13e-229	631.0	COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,247VY@186801|Clostridia,25UY1@186806|Eubacteriaceae	186801|Clostridia	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
HLKFIFDC_01372	411469.EUBHAL_01849	6.17e-231	642.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,248EM@186801|Clostridia,25UX4@186806|Eubacteriaceae	186801|Clostridia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
HLKFIFDC_01373	411469.EUBHAL_01848	0.0	1178.0	COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,25VH9@186806|Eubacteriaceae	186801|Clostridia	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
HLKFIFDC_01374	411469.EUBHAL_01847	8.63e-122	349.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,24MQK@186801|Clostridia,25W35@186806|Eubacteriaceae	186801|Clostridia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
HLKFIFDC_01375	411469.EUBHAL_01846	1.12e-242	667.0	COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,247K2@186801|Clostridia,25VB3@186806|Eubacteriaceae	186801|Clostridia	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
HLKFIFDC_01376	411469.EUBHAL_01845	5.9e-279	762.0	COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,247P8@186801|Clostridia,25VFR@186806|Eubacteriaceae	186801|Clostridia	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
HLKFIFDC_01377	411469.EUBHAL_01842	0.0	1176.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,247V8@186801|Clostridia,25UV2@186806|Eubacteriaceae	186801|Clostridia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
HLKFIFDC_01378	411469.EUBHAL_01840	1.1e-231	639.0	COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,247WY@186801|Clostridia,25V4D@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase,Glycos_trans_3N,Glycos_transf_3
HLKFIFDC_01379	411469.EUBHAL_01839	2.39e-296	808.0	COG0860@1|root,COG0860@2|Bacteria,1TSFS@1239|Firmicutes,2488U@186801|Clostridia,25UTM@186806|Eubacteriaceae	186801|Clostridia	M	stage II sporulation protein P	spoIIP	-	-	ko:K06385	-	-	-	-	ko00000	-	-	-	SpoIIP
HLKFIFDC_01380	411469.EUBHAL_01838	9.28e-221	609.0	COG0680@1|root,COG0680@2|Bacteria,1TPFY@1239|Firmicutes,248TE@186801|Clostridia,25V3S@186806|Eubacteriaceae	186801|Clostridia	C	Initiates the rapid degradation of small, acid-soluble proteins during spore germination	gpr	-	3.4.24.78	ko:K06012	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_A25
HLKFIFDC_01381	411469.EUBHAL_01837	7.93e-47	151.0	COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,24QNX@186801|Clostridia,25XFI@186806|Eubacteriaceae	186801|Clostridia	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
HLKFIFDC_01382	411469.EUBHAL_01836	2.48e-228	629.0	COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,24ASN@186801|Clostridia,25UZW@186806|Eubacteriaceae	186801|Clostridia	L	DNA polymerase III, delta' subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
HLKFIFDC_01383	411469.EUBHAL_01835	0.0	1566.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia,25VY4@186806|Eubacteriaceae	186801|Clostridia	S	DNA internalization competence protein ComEC Rec2-like protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
HLKFIFDC_01384	411469.EUBHAL_01834	2.08e-218	605.0	COG5401@1|root,COG5401@2|Bacteria,1UXYS@1239|Firmicutes,24EK4@186801|Clostridia,25W13@186806|Eubacteriaceae	186801|Clostridia	S	Sporulation and spore germination	-	-	-	ko:K06298	-	-	-	-	ko00000	-	-	-	Germane
HLKFIFDC_01385	411469.EUBHAL_01833	0.0	874.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,25UZG@186806|Eubacteriaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
HLKFIFDC_01386	411469.EUBHAL_01832	6.13e-164	458.0	COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,248Z4@186801|Clostridia,25VA8@186806|Eubacteriaceae	186801|Clostridia	T	response regulator	yycF	-	-	ko:K07668	ko02020,map02020	M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HLKFIFDC_01387	411469.EUBHAL_01831	1.47e-132	377.0	COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,24MQF@186801|Clostridia,25WWR@186806|Eubacteriaceae	186801|Clostridia	L	Psort location CytoplasmicMembrane, score	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
HLKFIFDC_01388	411469.EUBHAL_01830	6.52e-98	285.0	COG3238@1|root,COG3238@2|Bacteria,1V6J0@1239|Firmicutes,24JM9@186801|Clostridia,25WI3@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K09936	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.7.21	-	-	DMT_YdcZ
HLKFIFDC_01389	411469.EUBHAL_01829	5.18e-292	796.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,248C9@186801|Clostridia,25V0D@186806|Eubacteriaceae	186801|Clostridia	E	acetylornithine aminotransferase	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
HLKFIFDC_01390	411469.EUBHAL_01828	2.35e-209	580.0	COG0548@1|root,COG0548@2|Bacteria,1TP0N@1239|Firmicutes,2486J@186801|Clostridia,25UYD@186806|Eubacteriaceae	186801|Clostridia	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
HLKFIFDC_01391	411469.EUBHAL_01827	6.82e-292	797.0	COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,2497Q@186801|Clostridia,25V9D@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
HLKFIFDC_01392	411469.EUBHAL_01826	3.5e-252	691.0	COG0002@1|root,COG0002@2|Bacteria,1TPVI@1239|Firmicutes,247R3@186801|Clostridia,25V2D@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
HLKFIFDC_01393	411469.EUBHAL_01825	5.98e-307	835.0	COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,247MF@186801|Clostridia,25UVK@186806|Eubacteriaceae	186801|Clostridia	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
HLKFIFDC_01395	411469.EUBHAL_01817	6.53e-89	267.0	COG1396@1|root,COG1396@2|Bacteria,1VF0W@1239|Firmicutes,24R43@186801|Clostridia,25XCU@186806|Eubacteriaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HLKFIFDC_01396	411469.EUBHAL_01816	8.5e-91	266.0	COG4905@1|root,COG4905@2|Bacteria,1VA0H@1239|Firmicutes,2584X@186801|Clostridia,25Z4M@186806|Eubacteriaceae	186801|Clostridia	S	Putative ABC-transporter type IV	-	-	-	-	-	-	-	-	-	-	-	-	ABC_trans_CmpB
HLKFIFDC_01398	411469.EUBHAL_03299	5.42e-168	469.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia,25VT5@186806|Eubacteriaceae	186801|Clostridia	E	Psort location CytoplasmicMembrane, score	glnQ	-	3.6.3.21	ko:K02028,ko:K10041	ko02010,map02010	M00228,M00236	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
HLKFIFDC_01399	411469.EUBHAL_03300	2.16e-155	438.0	COG0765@1|root,COG0765@2|Bacteria,1TPM3@1239|Firmicutes,248UY@186801|Clostridia,25W65@186806|Eubacteriaceae	186801|Clostridia	P	ABC transporter, permease protein	ArtM	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1,SBP_bac_3
HLKFIFDC_01400	411469.EUBHAL_03029	9.99e-177	494.0	COG0834@1|root,COG0834@2|Bacteria,1TT16@1239|Firmicutes,24CEZ@186801|Clostridia,25W31@186806|Eubacteriaceae	186801|Clostridia	ET	Belongs to the bacterial solute-binding protein 3 family	artP	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
HLKFIFDC_01401	411469.EUBHAL_03028	2.04e-192	538.0	COG0697@1|root,COG0697@2|Bacteria,1TPUW@1239|Firmicutes,247X1@186801|Clostridia,25WBA@186806|Eubacteriaceae	186801|Clostridia	EG	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HLKFIFDC_01402	411469.EUBHAL_03026	0.0	916.0	COG0165@1|root,COG0165@2|Bacteria,1TNZ6@1239|Firmicutes,2489H@186801|Clostridia,25VGK@186806|Eubacteriaceae	186801|Clostridia	E	argininosuccinate lyase	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
HLKFIFDC_01403	411469.EUBHAL_03025	0.0	865.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,25V7V@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
HLKFIFDC_01404	411469.EUBHAL_03024	1.74e-252	692.0	COG0275@1|root,COG0275@2|Bacteria,1TP5R@1239|Firmicutes,248PH@186801|Clostridia,25VWE@186806|Eubacteriaceae	186801|Clostridia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH2	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
HLKFIFDC_01405	411469.EUBHAL_03023	1.71e-301	824.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,249Q3@186801|Clostridia,25VNG@186806|Eubacteriaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HLKFIFDC_01406	411469.EUBHAL_03022	2.56e-190	530.0	COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,24CAG@186801|Clostridia,25W19@186806|Eubacteriaceae	186801|Clostridia	M	Small conductance mechanosensitive ion channel, MscS family	mscS	-	-	ko:K03442,ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.2,1.A.23.3	-	-	MS_channel,TM_helix
HLKFIFDC_01407	411469.EUBHAL_03021	8.77e-262	717.0	COG0136@1|root,COG0136@2|Bacteria,1TPC6@1239|Firmicutes,248ZR@186801|Clostridia,25V5Z@186806|Eubacteriaceae	186801|Clostridia	E	Belongs to the aspartate-semialdehyde dehydrogenase family	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
HLKFIFDC_01408	411469.EUBHAL_03020	2.14e-278	761.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,248H9@186801|Clostridia,25VFK@186806|Eubacteriaceae	186801|Clostridia	C	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	pdxB	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
HLKFIFDC_01409	411469.EUBHAL_03019	0.0	1108.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,2480U@186801|Clostridia,25VJ7@186806|Eubacteriaceae	186801|Clostridia	H	Acetolactate synthase	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
HLKFIFDC_01410	411469.EUBHAL_03018	0.0	1101.0	COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,247UC@186801|Clostridia,25VFE@186806|Eubacteriaceae	186801|Clostridia	H	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
HLKFIFDC_01411	411469.EUBHAL_03017	2.39e-254	698.0	COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,24A63@186801|Clostridia,25VC9@186806|Eubacteriaceae	186801|Clostridia	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
HLKFIFDC_01412	411469.EUBHAL_03016	1.63e-185	515.0	COG5632@1|root,COG5632@2|Bacteria,1V3JT@1239|Firmicutes,24D7K@186801|Clostridia,25W7P@186806|Eubacteriaceae	186801|Clostridia	M	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01447	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Amidase_2
HLKFIFDC_01413	411469.EUBHAL_03015	0.0	939.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia,25UQN@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
HLKFIFDC_01414	1121333.JMLH01000005_gene521	1.01e-316	951.0	COG1196@1|root,COG3250@1|root,COG1196@2|Bacteria,COG3250@2|Bacteria,1TPK7@1239|Firmicutes,3VR8V@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Domain of unknown function (DUF4982)	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Big_4,DUF4982,F5_F8_type_C,FIVAR,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
HLKFIFDC_01416	411469.EUBHAL_00265	0.0	1268.0	COG1231@1|root,COG5492@1|root,COG1231@2|Bacteria,COG5492@2|Bacteria,1VUQN@1239|Firmicutes,24CDA@186801|Clostridia,25XH0@186806|Eubacteriaceae	186801|Clostridia	N	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF4430,F5_F8_type_C,FIVAR,Flg_new,RHS_repeat,SH3_3,SLH,fn3
HLKFIFDC_01417	411469.EUBHAL_00263	0.0	919.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,25UR0@186806|Eubacteriaceae	186801|Clostridia	C	NADPH-dependent glutamate synthase beta chain and related oxidoreductases	gltA	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
HLKFIFDC_01418	411469.EUBHAL_00262	1.92e-200	555.0	COG0543@1|root,COG0543@2|Bacteria,1TP6D@1239|Firmicutes,247YB@186801|Clostridia,25US8@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	nfnA	-	1.18.1.2,1.19.1.1	ko:K00528,ko:K16951	ko00920,ko01120,map00920,map01120	-	R00858,R10146,R10159	RC00065	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
HLKFIFDC_01419	411469.EUBHAL_00261	0.0	1133.0	COG0008@1|root,COG0008@2|Bacteria,1TP8G@1239|Firmicutes,247Y0@186801|Clostridia,25V0C@186806|Eubacteriaceae	186801|Clostridia	J	Psort location Cytoplasmic, score	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
HLKFIFDC_01420	411469.EUBHAL_00260	1.19e-151	426.0	COG3773@1|root,COG3773@2|Bacteria,1VN9A@1239|Firmicutes,25PXG@186801|Clostridia,25XWP@186806|Eubacteriaceae	186801|Clostridia	M	Cell Wall Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF348,G5,Hydrolase_2
HLKFIFDC_01421	411469.EUBHAL_02166	1.44e-47	172.0	COG5492@1|root,COG5492@2|Bacteria,1V4A5@1239|Firmicutes	1239|Firmicutes	N	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
HLKFIFDC_01423	411469.EUBHAL_00257	0.0	1197.0	COG1762@1|root,COG3711@1|root,COG1762@2|Bacteria,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,249R8@186801|Clostridia,25XAI@186806|Eubacteriaceae	186801|Clostridia	GKT	Psort location	-	-	-	ko:K03491	-	-	-	-	ko00000,ko03000	-	-	-	HTH_11,Mga,PRD,PTS_EIIA_2
HLKFIFDC_01424	411469.EUBHAL_00256	4.73e-82	243.0	COG3731@1|root,COG3731@2|Bacteria,1VG8V@1239|Firmicutes,24QUT@186801|Clostridia,25XAW@186806|Eubacteriaceae	186801|Clostridia	G	PTS system glucitol/sorbitol-specific IIA component	-	-	2.7.1.198	ko:K02781	ko00051,ko02060,map00051,map02060	M00280	R05820	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.4.1	-	-	PTSIIA_gutA
HLKFIFDC_01425	411469.EUBHAL_00255	2.41e-235	648.0	COG3732@1|root,COG3732@2|Bacteria,1TQ8F@1239|Firmicutes,2491P@186801|Clostridia,25VDV@186806|Eubacteriaceae	186801|Clostridia	G	Sorbitol phosphotransferase enzyme II N-terminus	srlE	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0090563	2.7.1.198	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	M00280	R05820	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.4.1	-	-	EIIBC-GUT_C,EIIBC-GUT_N
HLKFIFDC_01426	411469.EUBHAL_00254	1.49e-126	360.0	COG3730@1|root,COG3730@2|Bacteria,1URER@1239|Firmicutes,24DNG@186801|Clostridia,25W6B@186806|Eubacteriaceae	186801|Clostridia	G	PTS system enzyme II sorbitol-specific factor	srlA	-	-	ko:K02783	ko00051,ko02060,map00051,map02060	M00280	R05820	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.4.1	-	-	EII-GUT
HLKFIFDC_01427	411469.EUBHAL_00253	9.85e-99	287.0	COG4578@1|root,COG4578@2|Bacteria,1VHYU@1239|Firmicutes,24P6V@186801|Clostridia	186801|Clostridia	K	Glucitol operon activator	-	-	-	ko:K02466	-	-	-	-	ko00000	-	-	-	GutM
HLKFIFDC_01428	411469.EUBHAL_00252	1.82e-186	518.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,25VA9@186806|Eubacteriaceae	186801|Clostridia	IQ	Psort location Cytoplasmic, score	-	-	1.1.1.100,1.1.1.140	ko:K00059,ko:K00068	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R05607,R07759,R07763,R10116,R10120,R11671	RC00029,RC00085,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
HLKFIFDC_01429	411469.EUBHAL_00251	5.7e-114	328.0	COG0703@1|root,COG0703@2|Bacteria,1V3W6@1239|Firmicutes,24HKA@186801|Clostridia,25WG3@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
HLKFIFDC_01430	411469.EUBHAL_00250	5.42e-258	713.0	COG2333@1|root,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia,25WQW@186806|Eubacteriaceae	186801|Clostridia	N	Metallo-beta-lactamase superfamily	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Ada_Zn_binding,Lactamase_B
HLKFIFDC_01432	411469.EUBHAL_00240	6.04e-174	485.0	COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,247SC@186801|Clostridia,25VRV@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	yacO	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
HLKFIFDC_01433	411469.EUBHAL_00239	6.86e-98	284.0	COG1939@1|root,COG1939@2|Bacteria,1VA5V@1239|Firmicutes,24MR1@186801|Clostridia,25XH2@186806|Eubacteriaceae	186801|Clostridia	J	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)	mrnC	-	-	ko:K11145	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Ribonuclease_3
HLKFIFDC_01434	411469.EUBHAL_00238	0.0	919.0	COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,247KS@186801|Clostridia,25V4E@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
HLKFIFDC_01435	411469.EUBHAL_02778	6.51e-313	859.0	COG4552@1|root,COG4552@2|Bacteria,1V7PR@1239|Firmicutes,24A86@186801|Clostridia,25XCT@186806|Eubacteriaceae	186801|Clostridia	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9,SCP2_2
HLKFIFDC_01436	411469.EUBHAL_02779	1.75e-128	365.0	COG0245@1|root,COG0245@2|Bacteria,1V3P0@1239|Firmicutes,24HCM@186801|Clostridia,25WBC@186806|Eubacteriaceae	186801|Clostridia	H	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
HLKFIFDC_01439	411469.EUBHAL_02782	1.07e-285	780.0	COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,248AH@186801|Clostridia,25VU9@186806|Eubacteriaceae	186801|Clostridia	E	Peptidase dimerisation domain	dapL	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
HLKFIFDC_01440	411469.EUBHAL_02783	9.55e-96	280.0	2E4RH@1|root,32ZK1@2|Bacteria,1VEUS@1239|Firmicutes,24QIW@186801|Clostridia	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	DUF1700
HLKFIFDC_01441	411469.EUBHAL_02784	2.74e-266	728.0	COG5279@1|root,COG5279@2|Bacteria,1V8TE@1239|Firmicutes,24CI3@186801|Clostridia,25XC1@186806|Eubacteriaceae	186801|Clostridia	D	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CW_binding_2,Cu_amine_oxidN1,Transglut_core
HLKFIFDC_01442	411469.EUBHAL_02785	0.0	986.0	COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,25V1N@186806|Eubacteriaceae	186801|Clostridia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
HLKFIFDC_01443	411469.EUBHAL_02786	1.43e-52	166.0	COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,24MMM@186801|Clostridia,25X0R@186806|Eubacteriaceae	186801|Clostridia	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
HLKFIFDC_01445	411469.EUBHAL_02788	0.0	869.0	COG4219@1|root,COG4219@2|Bacteria,1TP3Z@1239|Firmicutes,249NV@186801|Clostridia,25VWV@186806|Eubacteriaceae	186801|Clostridia	KT	BlaR1 peptidase M56	-	-	-	ko:K02172	ko01501,map01501	M00627	-	-	ko00000,ko00001,ko00002,ko01002,ko01504	-	-	-	Peptidase_M23,Peptidase_M56,Transpeptidase
HLKFIFDC_01446	411469.EUBHAL_02789	1.21e-82	244.0	COG3682@1|root,COG3682@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
HLKFIFDC_01447	411469.EUBHAL_02791	9.07e-199	551.0	COG0697@1|root,COG0697@2|Bacteria,1TRKD@1239|Firmicutes,248I1@186801|Clostridia,25UV5@186806|Eubacteriaceae	186801|Clostridia	EG	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HLKFIFDC_01448	411469.EUBHAL_02792	2.85e-249	687.0	COG0726@1|root,COG0726@2|Bacteria,1V6DN@1239|Firmicutes,24MJ1@186801|Clostridia,25WI5@186806|Eubacteriaceae	186801|Clostridia	G	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Big_2,CW_binding_1,Cu_amine_oxidN1,DUF3298,Polysacc_deac_1,SH3_3
HLKFIFDC_01449	411469.EUBHAL_02793	6.33e-133	376.0	COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,249DV@186801|Clostridia,25UWQ@186806|Eubacteriaceae	186801|Clostridia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
HLKFIFDC_01450	411469.EUBHAL_02794	9.56e-121	345.0	COG2179@1|root,COG2179@2|Bacteria,1V6KM@1239|Firmicutes,24KK7@186801|Clostridia,25WAD@186806|Eubacteriaceae	186801|Clostridia	S	HAD-hyrolase-like	yqeG	-	-	ko:K07015	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase,Hydrolase_like,PGP_phosphatase
HLKFIFDC_01451	411469.EUBHAL_02795	4.86e-142	401.0	COG1191@1|root,COG1191@2|Bacteria,1TPJ5@1239|Firmicutes,247XH@186801|Clostridia,25WCT@186806|Eubacteriaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigK	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
HLKFIFDC_01452	411469.EUBHAL_02796	2.11e-271	744.0	COG0826@1|root,COG0826@2|Bacteria,1TPRE@1239|Firmicutes,248I3@186801|Clostridia,25V88@186806|Eubacteriaceae	186801|Clostridia	O	Peptidase, U32 family	yhbU_1	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
HLKFIFDC_01453	411469.EUBHAL_02797	6.39e-150	422.0	COG4122@1|root,COG4122@2|Bacteria,1UF4M@1239|Firmicutes,24B70@186801|Clostridia,25VZD@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	yrrM	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
HLKFIFDC_01455	411474.COPEUT_02945	2.17e-07	53.5	2ERJI@1|root,33J51@2|Bacteria,1VMP2@1239|Firmicutes	1239|Firmicutes	S	Control of competence regulator ComK, YlbF/YmcA	-	-	-	-	-	-	-	-	-	-	-	-	Com_YlbF
HLKFIFDC_01456	411469.EUBHAL_02800	0.0	1093.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,2488J@186801|Clostridia,25V02@186806|Eubacteriaceae	186801|Clostridia	J	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
HLKFIFDC_01457	411469.EUBHAL_02801	3.97e-59	182.0	2E3Y4@1|root,32YV4@2|Bacteria,1VFRH@1239|Firmicutes,24QXW@186801|Clostridia,25XRD@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF1292)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1292
HLKFIFDC_01458	411469.EUBHAL_02802	1.17e-95	279.0	COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,24JGP@186801|Clostridia,25X7S@186806|Eubacteriaceae	186801|Clostridia	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yrrK	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
HLKFIFDC_01459	411469.EUBHAL_02803	2.54e-55	172.0	COG4472@1|root,COG4472@2|Bacteria,1VAC4@1239|Firmicutes,24QVQ@186801|Clostridia,25XIM@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the UPF0297 family	yrzL	-	-	-	-	-	-	-	-	-	-	-	DUF965
HLKFIFDC_01460	411469.EUBHAL_02804	0.0	884.0	COG0621@1|root,COG0621@2|Bacteria,1TPBR@1239|Firmicutes,247IX@186801|Clostridia,25V0X@186806|Eubacteriaceae	186801|Clostridia	J	Psort location Cytoplasmic, score	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
HLKFIFDC_01461	411469.EUBHAL_02805	3.46e-47	152.0	COG1925@1|root,COG1925@2|Bacteria,1VAQP@1239|Firmicutes,24N19@186801|Clostridia,25X2B@186806|Eubacteriaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	PTS-HPr
HLKFIFDC_01462	411469.EUBHAL_02807	1.6e-285	781.0	COG0301@1|root,COG0301@2|Bacteria,1TPNW@1239|Firmicutes,247Y5@186801|Clostridia,25UQG@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	thiI	-	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	-	THUMP,ThiI
HLKFIFDC_01463	411469.EUBHAL_02808	3.15e-277	758.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,25V3Y@186806|Eubacteriaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
HLKFIFDC_01465	411469.EUBHAL_02630	0.0	926.0	COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia,25V0R@186806|Eubacteriaceae	186801|Clostridia	C	Conserved carboxylase domain	pycB	-	4.1.1.3	ko:K01571	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	HMGL-like,PYC_OADA
HLKFIFDC_01466	411469.EUBHAL_02631	5.11e-247	681.0	COG1883@1|root,COG1883@2|Bacteria,1TPEP@1239|Firmicutes,248ET@186801|Clostridia,25V7P@186806|Eubacteriaceae	186801|Clostridia	C	decarboxylase, beta subunit	gcdB	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
HLKFIFDC_01467	411469.EUBHAL_02632	1.08e-71	216.0	COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,25WYH@186806|Eubacteriaceae	186801|Clostridia	I	Biotin-requiring enzyme	gcdC	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
HLKFIFDC_01468	411469.EUBHAL_02633	1.25e-27	104.0	2DMIV@1|root,32RW6@2|Bacteria,1VAMW@1239|Firmicutes,24DVC@186801|Clostridia	186801|Clostridia	P	decarboxylase gamma	-	-	-	-	-	-	-	-	-	-	-	-	DUF3887,OAD_gamma
HLKFIFDC_01469	411469.EUBHAL_02634	0.0	902.0	COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia,25VP1@186806|Eubacteriaceae	186801|Clostridia	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
HLKFIFDC_01470	411469.EUBHAL_02635	3.07e-156	437.0	COG0461@1|root,COG0461@2|Bacteria,1V23H@1239|Firmicutes,24FTS@186801|Clostridia,25WAA@186806|Eubacteriaceae	186801|Clostridia	F	orotate phosphoribosyltransferase K00762	-	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	-
HLKFIFDC_01471	357809.Cphy_0955	5.83e-82	258.0	COG1082@1|root,COG1082@2|Bacteria,1U2VB@1239|Firmicutes,24EE7@186801|Clostridia	186801|Clostridia	G	PFAM Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
HLKFIFDC_01472	138119.DSY3851	8.06e-86	283.0	COG1129@1|root,COG4720@1|root,COG1129@2|Bacteria,COG4720@2|Bacteria,1TQRP@1239|Firmicutes,24YCF@186801|Clostridia,267B9@186807|Peptococcaceae	186801|Clostridia	G	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran,ECF-ribofla_trS,ECF_trnsprt
HLKFIFDC_01473	903814.ELI_3900	1.91e-266	747.0	COG1129@1|root,COG1129@2|Bacteria,1TQRP@1239|Firmicutes,24YCF@186801|Clostridia,25VMB@186806|Eubacteriaceae	186801|Clostridia	G	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran,ECF-ribofla_trS
HLKFIFDC_01474	931626.Awo_c30600	2.97e-118	350.0	COG0619@1|root,COG0619@2|Bacteria,1TSB5@1239|Firmicutes,24AN7@186801|Clostridia,25WAW@186806|Eubacteriaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
HLKFIFDC_01475	1121115.AXVN01000071_gene3940	3.06e-94	297.0	COG2247@1|root,COG2247@2|Bacteria,1UNK1@1239|Firmicutes,25H40@186801|Clostridia	186801|Clostridia	M	Domain of unknown function (DUF4430)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4430
HLKFIFDC_01476	1121115.AXVN01000071_gene3941	4.89e-99	332.0	COG1657@1|root,COG5492@1|root,COG1657@2|Bacteria,COG5492@2|Bacteria,1UZVS@1239|Firmicutes,24DV2@186801|Clostridia,3Y094@572511|Blautia	186801|Clostridia	IN	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF4430,Prenyltrans,SLH,SQHop_cyclase_C
HLKFIFDC_01477	903814.ELI_3905	1.4e-42	169.0	COG1520@1|root,COG5492@1|root,COG1520@2|Bacteria,COG5492@2|Bacteria,1UYNK@1239|Firmicutes,24C3F@186801|Clostridia,25XE2@186806|Eubacteriaceae	186801|Clostridia	M	Cadherin-like beta sandwich domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Big_3,CW_binding_2,Cadherin-like,DUF4430,PEGA,PQQ_2,PQQ_3
HLKFIFDC_01478	33035.JPJF01000054_gene1633	2.85e-273	843.0	COG2340@1|root,COG2340@2|Bacteria,1V1IM@1239|Firmicutes,24PYX@186801|Clostridia	186801|Clostridia	N	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01480	1395513.P343_11555	5.6e-18	93.2	COG2207@1|root,COG3708@1|root,COG2207@2|Bacteria,COG3708@2|Bacteria,1TPI9@1239|Firmicutes,4IQDH@91061|Bacilli	91061|Bacilli	K	Bacterial transcription activator, effector binding domain	-	-	-	ko:K13653	-	-	-	-	ko00000,ko03000	-	-	-	Cass2,HTH_18
HLKFIFDC_01481	768704.Desmer_0587	3.16e-45	161.0	COG2207@1|root,COG3708@1|root,COG2207@2|Bacteria,COG3708@2|Bacteria,1V5FF@1239|Firmicutes,25B27@186801|Clostridia,263FB@186807|Peptococcaceae	186801|Clostridia	K	Bacterial transcription activator, effector binding domain	-	-	-	ko:K13653	-	-	-	-	ko00000,ko03000	-	-	-	Cass2,HTH_18
HLKFIFDC_01482	411469.EUBHAL_02642	6.23e-56	174.0	2E0EA@1|root,32W0W@2|Bacteria,1VB0V@1239|Firmicutes,24R8X@186801|Clostridia,25YX0@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01490	411469.EUBHAL_00596	0.0	1003.0	COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,247RA@186801|Clostridia,25VF6@186806|Eubacteriaceae	186801|Clostridia	E	Orn Lys Arg decarboxylase, major domain	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C
HLKFIFDC_01491	411469.EUBHAL_00595	1.24e-144	408.0	COG0125@1|root,COG0125@2|Bacteria,1V1HE@1239|Firmicutes,24HHC@186801|Clostridia,25WNR@186806|Eubacteriaceae	186801|Clostridia	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
HLKFIFDC_01492	411469.EUBHAL_00594	2.26e-242	666.0	COG2812@1|root,COG2812@2|Bacteria,1VCQC@1239|Firmicutes,248U4@186801|Clostridia,25VT1@186806|Eubacteriaceae	186801|Clostridia	L	DNA polymerase III	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
HLKFIFDC_01493	411469.EUBHAL_00593	3.58e-207	573.0	COG1774@1|root,COG1774@2|Bacteria,1TP1V@1239|Firmicutes,247Q6@186801|Clostridia,25VAY@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	yaaT	-	-	-	-	-	-	-	-	-	-	-	PSP1
HLKFIFDC_01494	411469.EUBHAL_00592	1.98e-179	499.0	COG4123@1|root,COG4123@2|Bacteria,1TQ25@1239|Firmicutes,249UH@186801|Clostridia,25UWI@186806|Eubacteriaceae	186801|Clostridia	S	Methyltransferase small domain	yfiC	-	2.1.1.223	ko:K15460	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MTS,Methyltransf_31
HLKFIFDC_01495	411469.EUBHAL_00591	2.71e-197	547.0	COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,24864@186801|Clostridia,25V9Q@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
HLKFIFDC_01496	411469.EUBHAL_00590	1.99e-129	379.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF4430,LRR_5
HLKFIFDC_01497	411469.EUBHAL_00589	0.0	1269.0	COG1315@1|root,COG1315@2|Bacteria,1TRQX@1239|Firmicutes,24BWZ@186801|Clostridia	186801|Clostridia	L	Psort location Cellwall, score	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind,SLH
HLKFIFDC_01498	411469.EUBHAL_00588	2.08e-275	753.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,2480T@186801|Clostridia,25VRF@186806|Eubacteriaceae	186801|Clostridia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
HLKFIFDC_01499	1232453.BAIF02000111_gene617	3.01e-10	63.5	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4,PAS_9
HLKFIFDC_01500	411469.EUBHAL_00586	3.23e-144	407.0	COG2715@1|root,COG2715@2|Bacteria,1V1E2@1239|Firmicutes,249G0@186801|Clostridia,25W3R@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	spmA	-	-	ko:K06373	-	-	-	-	ko00000	-	-	-	Gate
HLKFIFDC_01501	411469.EUBHAL_00585	2.98e-111	321.0	COG0700@1|root,COG0700@2|Bacteria,1V45M@1239|Firmicutes,24HSJ@186801|Clostridia,25WAH@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	spmB	-	-	ko:K06374	-	-	-	-	ko00000	-	-	-	Gate
HLKFIFDC_01502	411469.EUBHAL_00584	4.34e-177	492.0	2A0UZ@1|root,30NZW@2|Bacteria,1V4U0@1239|Firmicutes,24F0B@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01504	411469.EUBHAL_00583	3.14e-138	390.0	COG1443@1|root,COG1443@2|Bacteria,1UIPC@1239|Firmicutes,25EQ3@186801|Clostridia	186801|Clostridia	I	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
HLKFIFDC_01506	411469.EUBHAL_00581	0.0	894.0	COG1376@1|root,COG1376@2|Bacteria,1TQMA@1239|Firmicutes,248H0@186801|Clostridia,25VRN@186806|Eubacteriaceae	186801|Clostridia	M	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
HLKFIFDC_01507	411469.EUBHAL_00580	1.26e-244	672.0	COG1609@1|root,COG1609@2|Bacteria,1UK1H@1239|Firmicutes,249XN@186801|Clostridia,25WAY@186806|Eubacteriaceae	186801|Clostridia	K	Bacterial regulatory proteins, lacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
HLKFIFDC_01508	411469.EUBHAL_00579	3.48e-223	617.0	COG0715@1|root,COG0715@2|Bacteria,1TT2F@1239|Firmicutes,249M2@186801|Clostridia,25XCS@186806|Eubacteriaceae	186801|Clostridia	P	Substrate binding domain of ABC-type glycine betaine transport system	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1_2,Phosphonate-bd
HLKFIFDC_01509	411469.EUBHAL_00578	5.44e-176	490.0	COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,248CG@186801|Clostridia,25W8W@186806|Eubacteriaceae	186801|Clostridia	P	ABC-type nitrate sulfonate bicarbonate transport system, ATPase component	-	-	3.6.3.36	ko:K02049,ko:K10831	ko00920,ko02010,map00920,map02010	M00188,M00435	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.1,3.A.1.17.4	-	-	ABC_tran
HLKFIFDC_01510	411469.EUBHAL_00577	4.1e-177	494.0	COG0600@1|root,COG0600@2|Bacteria,1TR6A@1239|Firmicutes,247VM@186801|Clostridia,25X9W@186806|Eubacteriaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050,ko:K15552	ko00920,ko02010,map00920,map02010	M00188,M00435	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.1,3.A.1.17.4	-	-	BPD_transp_1
HLKFIFDC_01511	658086.HMPREF0994_00423	1.63e-55	185.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1URF2@1239|Firmicutes,24BBP@186801|Clostridia,27K82@186928|unclassified Lachnospiraceae	186801|Clostridia	T	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC,Response_reg
HLKFIFDC_01512	180332.JTGN01000005_gene2903	8.28e-90	295.0	COG2972@1|root,COG2972@2|Bacteria,1U6WN@1239|Firmicutes,24CTB@186801|Clostridia	186801|Clostridia	T	K07718 two-component system, sensor histidine kinase YesM	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,His_kinase
HLKFIFDC_01513	180332.JTGN01000005_gene2902	5.97e-203	579.0	COG1653@1|root,COG1653@2|Bacteria,1TPWV@1239|Firmicutes,24AWQ@186801|Clostridia	186801|Clostridia	G	solute-binding protein	-	-	-	ko:K17318	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	DUF3502,SBP_bac_8
HLKFIFDC_01514	180332.JTGN01000005_gene2900	3.14e-265	805.0	COG1231@1|root,COG5492@1|root,COG1231@2|Bacteria,COG5492@2|Bacteria,1TQW0@1239|Firmicutes,24CW5@186801|Clostridia	186801|Clostridia	E	Protein of unknown function (DUF1593)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1593
HLKFIFDC_01515	697329.Rumal_3660	1.15e-217	606.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia,3WJ00@541000|Ruminococcaceae	186801|Clostridia	L	transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
HLKFIFDC_01516	411469.EUBHAL_02860	1.68e-11	64.7	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,25V1G@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
HLKFIFDC_01517	411469.EUBHAL_00576	0.0	1347.0	COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,1TPJD@1239|Firmicutes,24810@186801|Clostridia,25VB6@186806|Eubacteriaceae	186801|Clostridia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topB	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim
HLKFIFDC_01518	411469.EUBHAL_00575	0.0	1045.0	COG4990@1|root,COG4990@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_3,Lysozyme_like,Peptidase_C39_2,SH3_3
HLKFIFDC_01519	411469.EUBHAL_00574	0.0	1095.0	COG3044@1|root,COG3044@2|Bacteria,1TPJ9@1239|Firmicutes,248G5@186801|Clostridia,25URY@186806|Eubacteriaceae	186801|Clostridia	S	Predicted ATPase of the ABC class	-	-	-	-	-	-	-	-	-	-	-	-	ABC_ATPase
HLKFIFDC_01520	411469.EUBHAL_02574	1.35e-11	60.5	2DXIG@1|root,3455C@2|Bacteria,1VYKU@1239|Firmicutes,2542Y@186801|Clostridia,25Z6G@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01521	411469.EUBHAL_00572	4.56e-246	677.0	COG0544@1|root,COG0544@2|Bacteria,1V21F@1239|Firmicutes,24G64@186801|Clostridia,25YV8@186806|Eubacteriaceae	186801|Clostridia	O	Bacterial trigger factor protein (TF) C-terminus	-	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	Trigger_C
HLKFIFDC_01522	411469.EUBHAL_00571	1.97e-183	510.0	COG0149@1|root,COG0149@2|Bacteria,1UYUE@1239|Firmicutes,248TQ@186801|Clostridia,25WD9@186806|Eubacteriaceae	186801|Clostridia	G	Triosephosphate isomerase	-	-	5.3.1.1,5.3.1.33	ko:K01803,ko:K21910	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
HLKFIFDC_01523	411469.EUBHAL_00570	2.87e-83	246.0	COG3412@1|root,COG3412@2|Bacteria,1VF32@1239|Firmicutes,24N8B@186801|Clostridia,25X2F@186806|Eubacteriaceae	186801|Clostridia	S	Dihydroxyacetone kinase, phosphotransfer subunit	-	-	2.7.1.121	ko:K05881	ko00561,map00561	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000,ko02000	-	-	-	EIIA-man
HLKFIFDC_01524	411469.EUBHAL_00569	1.42e-244	671.0	COG2376@1|root,COG2376@2|Bacteria,1TP92@1239|Firmicutes,2488D@186801|Clostridia,25V93@186806|Eubacteriaceae	186801|Clostridia	G	Dak1 domain	-	-	2.7.1.121	ko:K05878	ko00561,ko01100,map00561,map01100	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000	-	-	-	Dak1
HLKFIFDC_01525	411469.EUBHAL_00568	2.41e-150	423.0	COG1461@1|root,COG1461@2|Bacteria,1V1ZG@1239|Firmicutes,24CF0@186801|Clostridia,25VWQ@186806|Eubacteriaceae	186801|Clostridia	S	Dak2	-	-	2.7.1.121	ko:K05879	ko00561,ko01100,map00561,map01100	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000	-	-	-	Dak2
HLKFIFDC_01526	411469.EUBHAL_00567	0.0	999.0	COG0554@1|root,COG0554@2|Bacteria,1V02F@1239|Firmicutes,24C5X@186801|Clostridia,25UZV@186806|Eubacteriaceae	186801|Clostridia	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	-	-	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
HLKFIFDC_01527	411469.EUBHAL_00566	0.0	954.0	COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia,25VVU@186806|Eubacteriaceae	186801|Clostridia	C	BFD-like [2Fe-2S] binding domain	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD
HLKFIFDC_01528	411469.EUBHAL_00565	4.26e-308	840.0	COG0446@1|root,COG0446@2|Bacteria,1TQH5@1239|Firmicutes,247YR@186801|Clostridia,25VE0@186806|Eubacteriaceae	186801|Clostridia	C	HI0933-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
HLKFIFDC_01529	411469.EUBHAL_00564	1.76e-63	195.0	COG3862@1|root,COG3862@2|Bacteria,1VHQB@1239|Firmicutes,24T0T@186801|Clostridia,25XGU@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF1667)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1667
HLKFIFDC_01530	411469.EUBHAL_00563	2.87e-132	375.0	COG1954@1|root,COG1954@2|Bacteria,1V4IE@1239|Firmicutes,24I8Z@186801|Clostridia,25WCP@186806|Eubacteriaceae	186801|Clostridia	K	Glycerol-3-phosphate responsive antiterminator	-	-	-	ko:K02443	-	-	-	-	ko00000,ko03000	-	-	-	G3P_antiterm
HLKFIFDC_01532	411469.EUBHAL_00561	9.28e-89	260.0	COG1476@1|root,COG1476@2|Bacteria,1VCHW@1239|Firmicutes,24TP0@186801|Clostridia,25ZDY@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01534	411469.EUBHAL_00560	0.0	1098.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,25VNK@186806|Eubacteriaceae	186801|Clostridia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_2
HLKFIFDC_01535	411469.EUBHAL_00559	2.68e-252	691.0	COG0722@1|root,COG0722@2|Bacteria,1TQI4@1239|Firmicutes,24842@186801|Clostridia,25V2I@186806|Eubacteriaceae	186801|Clostridia	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroH	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS07240	DAHP_synth_1
HLKFIFDC_01536	411469.EUBHAL_00558	1.42e-159	447.0	COG0745@1|root,COG0745@2|Bacteria,1V2HA@1239|Firmicutes,24G2X@186801|Clostridia	186801|Clostridia	K	Response regulator receiver domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HLKFIFDC_01537	411469.EUBHAL_00557	2.47e-241	667.0	COG0860@1|root,COG0860@2|Bacteria,1UYPW@1239|Firmicutes,24BHU@186801|Clostridia,25XJU@186806|Eubacteriaceae	186801|Clostridia	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,Cu_amine_oxidN1
HLKFIFDC_01538	411469.EUBHAL_00556	0.0	1450.0	COG1328@1|root,COG1328@2|Bacteria,1TR9K@1239|Firmicutes,247WF@186801|Clostridia,25UVA@186806|Eubacteriaceae	186801|Clostridia	F	Psort location Cytoplasmic, score	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
HLKFIFDC_01539	411469.EUBHAL_00555	6.18e-130	368.0	COG0602@1|root,COG0602@2|Bacteria,1V1HG@1239|Firmicutes,24HIJ@186801|Clostridia,25W8H@186806|Eubacteriaceae	186801|Clostridia	O	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	nrdG	-	1.97.1.4	ko:K04068	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
HLKFIFDC_01541	411469.EUBHAL_00553	1.05e-144	410.0	2E6QY@1|root,331B3@2|Bacteria,1VGA3@1239|Firmicutes,24QJZ@186801|Clostridia,25ZD3@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4203
HLKFIFDC_01542	411469.EUBHAL_00552	0.0	978.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,25UWV@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
HLKFIFDC_01545	411469.EUBHAL_00934	0.0	1090.0	COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia,25VDG@186806|Eubacteriaceae	186801|Clostridia	H	Formyltetrahydrofolate synthetase	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
HLKFIFDC_01546	411469.EUBHAL_00933	2.21e-311	849.0	2DBS2@1|root,2ZAP4@2|Bacteria,1V6HV@1239|Firmicutes,24K80@186801|Clostridia,25WP5@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01547	411469.EUBHAL_00932	1.86e-213	590.0	COG0524@1|root,COG0524@2|Bacteria,1TQRC@1239|Firmicutes,249QQ@186801|Clostridia,25X4Z@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
HLKFIFDC_01549	411469.EUBHAL_00927	5.96e-271	742.0	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,249CS@186801|Clostridia,25UZN@186806|Eubacteriaceae	186801|Clostridia	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
HLKFIFDC_01552	411469.EUBHAL_02975	3.83e-233	644.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia,25VBA@186806|Eubacteriaceae	186801|Clostridia	L	Probable transposase	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
HLKFIFDC_01553	411469.EUBHAL_00925	6.19e-53	167.0	2C8M8@1|root,2ZGT2@2|Bacteria,1W4A3@1239|Firmicutes,24TMV@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01554	1280673.AUJJ01000020_gene1343	2.05e-19	85.5	COG1669@1|root,COG1669@2|Bacteria,1UQZM@1239|Firmicutes,25JKR@186801|Clostridia,4C0HW@830|Butyrivibrio	186801|Clostridia	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
HLKFIFDC_01555	411469.EUBHAL_00923	0.0	1075.0	COG1866@1|root,COG1866@2|Bacteria,1TPQV@1239|Firmicutes,248JE@186801|Clostridia,25VG1@186806|Eubacteriaceae	186801|Clostridia	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
HLKFIFDC_01556	411469.EUBHAL_00922	0.0	1189.0	COG4805@1|root,COG4805@2|Bacteria,1TREN@1239|Firmicutes,249U9@186801|Clostridia,25VWB@186806|Eubacteriaceae	186801|Clostridia	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
HLKFIFDC_01557	411469.EUBHAL_00921	0.0	1305.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,248AU@186801|Clostridia,25VBG@186806|Eubacteriaceae	186801|Clostridia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
HLKFIFDC_01558	411469.EUBHAL_00920	1.1e-184	513.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,248HE@186801|Clostridia,25V0F@186806|Eubacteriaceae	186801|Clostridia	L	hydrolase, TatD family	ycfH	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
HLKFIFDC_01559	411469.EUBHAL_00918	1.23e-200	556.0	COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,248RY@186801|Clostridia,25V9W@186806|Eubacteriaceae	186801|Clostridia	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
HLKFIFDC_01560	411469.EUBHAL_00917	3.09e-236	661.0	2BZEU@1|root,30VT8@2|Bacteria,1V54M@1239|Firmicutes,24SSI@186801|Clostridia,25X67@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01561	411469.EUBHAL_00916	2.19e-117	336.0	COG0590@1|root,COG0590@2|Bacteria,1V3HZ@1239|Firmicutes,24JM2@186801|Clostridia,25W7A@186806|Eubacteriaceae	186801|Clostridia	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
HLKFIFDC_01563	411469.EUBHAL_00911	0.0	1353.0	COG0073@1|root,COG1384@1|root,COG0073@2|Bacteria,COG1384@2|Bacteria,1TR1T@1239|Firmicutes,24DBQ@186801|Clostridia	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04566	ko00970,map00970	M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1f,tRNA_bind
HLKFIFDC_01564	411469.EUBHAL_00910	1.35e-102	297.0	COG0369@1|root,COG1151@2|Bacteria,1VM38@1239|Firmicutes,24WM1@186801|Clostridia	186801|Clostridia	P	hydroxylamine reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01566	411469.EUBHAL_00908	0.0	1171.0	COG5279@1|root,COG5492@1|root,COG5279@2|Bacteria,COG5492@2|Bacteria,1VQT7@1239|Firmicutes	1239|Firmicutes	D	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
HLKFIFDC_01567	411469.EUBHAL_00907	0.0	1192.0	COG1164@1|root,COG1164@2|Bacteria,1TP4P@1239|Firmicutes,248TP@186801|Clostridia,25VGD@186806|Eubacteriaceae	186801|Clostridia	E	oligoendopeptidase F	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
HLKFIFDC_01569	411469.EUBHAL_00905	0.0	868.0	COG2607@1|root,COG2607@2|Bacteria,1TQDJ@1239|Firmicutes,2483S@186801|Clostridia,25VCM@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K06923	-	-	-	-	ko00000	-	-	-	DUF815
HLKFIFDC_01570	537007.BLAHAN_06407	5.97e-13	64.3	2EIJI@1|root,33CAV@2|Bacteria,1VK5E@1239|Firmicutes,24MMQ@186801|Clostridia,3Y0TE@572511|Blautia	186801|Clostridia	S	COG NOG17864 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	SASP
HLKFIFDC_01572	411469.EUBHAL_00902	9.42e-174	484.0	COG1216@1|root,COG1216@2|Bacteria,1V3IY@1239|Firmicutes,24GIC@186801|Clostridia,25WHC@186806|Eubacteriaceae	186801|Clostridia	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HLKFIFDC_01573	411469.EUBHAL_00901	0.0	1776.0	COG4485@1|root,COG4485@2|Bacteria,1TRR1@1239|Firmicutes,24BHM@186801|Clostridia,25V75@186806|Eubacteriaceae	186801|Clostridia	S	CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	GtrA,YfhO
HLKFIFDC_01574	411469.EUBHAL_00900	1.04e-192	536.0	COG4086@1|root,COG4086@2|Bacteria,1TR2I@1239|Firmicutes,24C10@186801|Clostridia,25W3K@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF1002)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1002
HLKFIFDC_01577	411469.EUBHAL_00897	2.61e-280	767.0	COG4962@1|root,COG4962@2|Bacteria,1TQ0Z@1239|Firmicutes,249VS@186801|Clostridia,25US5@186806|Eubacteriaceae	186801|Clostridia	U	Type II IV secretion system protein	ptlH	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
HLKFIFDC_01578	411469.EUBHAL_00896	6.98e-111	323.0	COG4965@1|root,COG4965@2|Bacteria	2|Bacteria	U	Type ii secretion system	tadB	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
HLKFIFDC_01579	411469.EUBHAL_00895	3.42e-297	813.0	COG2064@1|root,COG2064@2|Bacteria,1V2C3@1239|Firmicutes,24AN4@186801|Clostridia,25WIH@186806|Eubacteriaceae	186801|Clostridia	NU	Psort location CytoplasmicMembrane, score	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
HLKFIFDC_01580	658086.HMPREF0994_06764	2.59e-11	60.5	2EHSI@1|root,33BI9@2|Bacteria,1VK7K@1239|Firmicutes,24UF9@186801|Clostridia,27QCR@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Putative Flagellin, Flp1-like, domain	-	-	-	-	-	-	-	-	-	-	-	-	Flp1_like
HLKFIFDC_01581	411469.EUBHAL_00893	0.0	968.0	2BXNJ@1|root,2ZC8M@2|Bacteria,1UYM5@1239|Firmicutes,24ASZ@186801|Clostridia,25WG5@186806|Eubacteriaceae	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01582	411469.EUBHAL_00892	6.93e-220	607.0	COG4961@1|root,COG4961@2|Bacteria,1V9E1@1239|Firmicutes,24ET0@186801|Clostridia,25XBZ@186806|Eubacteriaceae	186801|Clostridia	U	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TadE
HLKFIFDC_01584	411469.EUBHAL_00890	0.0	1045.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	ko:K08777	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	FHA
HLKFIFDC_01585	411469.EUBHAL_00889	2.15e-237	654.0	COG0705@1|root,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,247PT@186801|Clostridia,25X44@186806|Eubacteriaceae	186801|Clostridia	S	Rhomboid family	gluP	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
HLKFIFDC_01586	411469.EUBHAL_00888	6.88e-257	704.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,249AM@186801|Clostridia,25VKJ@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
HLKFIFDC_01587	411469.EUBHAL_00887	2.17e-140	396.0	COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,2487H@186801|Clostridia,25UW1@186806|Eubacteriaceae	186801|Clostridia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
HLKFIFDC_01588	411469.EUBHAL_00886	1.57e-57	181.0	COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,24MXH@186801|Clostridia,25WJP@186806|Eubacteriaceae	186801|Clostridia	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
HLKFIFDC_01589	411469.EUBHAL_00884	0.0	1097.0	COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,247J7@186801|Clostridia,25V0H@186806|Eubacteriaceae	186801|Clostridia	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
HLKFIFDC_01590	411469.EUBHAL_00883	2.01e-242	665.0	COG2334@1|root,COG2334@2|Bacteria,1TTBS@1239|Firmicutes,2483F@186801|Clostridia,25W8P@186806|Eubacteriaceae	186801|Clostridia	S	Spore coat protein	cotS	-	-	ko:K06331,ko:K06337	-	-	-	-	ko00000	-	-	-	APH,Choline_kinase
HLKFIFDC_01591	411469.EUBHAL_00882	0.0	888.0	COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,247XC@186801|Clostridia,25VGZ@186806|Eubacteriaceae	186801|Clostridia	H	tRNA nucleotidyltransferase poly(A) polymerase	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
HLKFIFDC_01592	411469.EUBHAL_00881	1.6e-109	316.0	2DD3J@1|root,32U0T@2|Bacteria,1VB00@1239|Firmicutes,24N49@186801|Clostridia,25X54@186806|Eubacteriaceae	186801|Clostridia	S	PrcB C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PrcB_C
HLKFIFDC_01593	411469.EUBHAL_00880	0.0	1013.0	COG1388@1|root,COG1388@2|Bacteria,1TSVC@1239|Firmicutes,248VQ@186801|Clostridia,25VZU@186806|Eubacteriaceae	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3794,LysM
HLKFIFDC_01594	657322.FPR_05110	3.9e-18	85.9	2EMVY@1|root,31QVD@2|Bacteria,1TV7K@1239|Firmicutes,259W4@186801|Clostridia,3WQSZ@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01596	748224.HMPREF9436_02795	1.57e-88	265.0	COG0681@1|root,COG0681@2|Bacteria,1V542@1239|Firmicutes,24I8N@186801|Clostridia,3WIUD@541000|Ruminococcaceae	186801|Clostridia	U	Signal peptidase, peptidase S26	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
HLKFIFDC_01597	1235796.C815_01374	2.07e-15	89.7	COG4932@1|root,COG4932@2|Bacteria,1V456@1239|Firmicutes	1239|Firmicutes	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GramPos_pilinBB,Gram_pos_anchor
HLKFIFDC_01598	411469.EUBHAL_00758	1.7e-119	350.0	COG5464@1|root,COG5464@2|Bacteria,1V263@1239|Firmicutes,25FNN@186801|Clostridia,25ZUE@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
HLKFIFDC_01600	411469.EUBHAL_00876	4.96e-07	52.4	COG3764@1|root,COG3764@2|Bacteria,1UN9R@1239|Firmicutes,24CEQ@186801|Clostridia,25WDG@186806|Eubacteriaceae	186801|Clostridia	M	Sortase family	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
HLKFIFDC_01601	411469.EUBHAL_00876	7.29e-50	166.0	COG3764@1|root,COG3764@2|Bacteria,1UN9R@1239|Firmicutes,24CEQ@186801|Clostridia,25WDG@186806|Eubacteriaceae	186801|Clostridia	M	Sortase family	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
HLKFIFDC_01602	411469.EUBHAL_00876	1.52e-61	197.0	COG3764@1|root,COG3764@2|Bacteria,1UN9R@1239|Firmicutes,24CEQ@186801|Clostridia,25WDG@186806|Eubacteriaceae	186801|Clostridia	M	Sortase family	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
HLKFIFDC_01603	411469.EUBHAL_00875	1.28e-148	419.0	COG1802@1|root,COG1802@2|Bacteria,1TSV2@1239|Firmicutes,24C0U@186801|Clostridia,25V16@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	ydfH_4	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
HLKFIFDC_01604	411469.EUBHAL_00874	1.63e-232	640.0	COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,24898@186801|Clostridia,25VAB@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
HLKFIFDC_01605	411469.EUBHAL_00873	0.0	1006.0	COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,248Q8@186801|Clostridia,25V1Z@186806|Eubacteriaceae	186801|Clostridia	EG	Psort location CytoplasmicMembrane, score	gerA	-	-	ko:K06310,ko:K06408	-	-	-	-	ko00000	-	-	-	GerA
HLKFIFDC_01606	411469.EUBHAL_00872	0.0	1187.0	COG0531@1|root,COG0531@2|Bacteria,1TZQ6@1239|Firmicutes,24EQ1@186801|Clostridia	186801|Clostridia	E	TIGRFAM Spore germination	-	-	-	ko:K06296,ko:K06311	-	-	-	-	ko00000,ko02000	2.A.3.9.3,2.A.3.9.4	-	-	Spore_permease
HLKFIFDC_01607	411469.EUBHAL_02407	1.89e-138	392.0	2AUKD@1|root,31K93@2|Bacteria,1V6PK@1239|Firmicutes,24J91@186801|Clostridia,25WIU@186806|Eubacteriaceae	186801|Clostridia	S	stage II sporulation protein R	spoIIR	-	-	ko:K06387	-	-	-	-	ko00000	-	-	-	Spore_II_R
HLKFIFDC_01608	411469.EUBHAL_02408	5.48e-233	640.0	COG1305@1|root,COG1305@2|Bacteria,1TP7G@1239|Firmicutes,24BSB@186801|Clostridia,25WBZ@186806|Eubacteriaceae	186801|Clostridia	E	Transglutaminase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
HLKFIFDC_01609	411469.EUBHAL_02409	1.36e-229	634.0	COG1459@1|root,COG1459@2|Bacteria,1TQRZ@1239|Firmicutes,249FV@186801|Clostridia,25WG2@186806|Eubacteriaceae	186801|Clostridia	U	Type II secretory pathway, component PulF	gspF	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
HLKFIFDC_01610	411469.EUBHAL_02410	1.6e-75	225.0	2E4EX@1|root,32ZA3@2|Bacteria,1VEQT@1239|Firmicutes,24QUI@186801|Clostridia,25XR7@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01611	411469.EUBHAL_02411	2.47e-107	310.0	2E9V5@1|root,33410@2|Bacteria,1VEQY@1239|Firmicutes,24J21@186801|Clostridia,25XVQ@186806|Eubacteriaceae	186801|Clostridia	S	Domain of unknown function (DUF4860)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4860
HLKFIFDC_01612	411469.EUBHAL_02412	1.06e-90	266.0	2EJ1P@1|root,33CSV@2|Bacteria,1VMCT@1239|Firmicutes,24Q8Q@186801|Clostridia,25XUC@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01613	411469.EUBHAL_02413	6.55e-79	239.0	2EIJK@1|root,33CAX@2|Bacteria,1VKEQ@1239|Firmicutes,24WKC@186801|Clostridia,25XZC@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01614	411469.EUBHAL_02414	5.43e-236	651.0	COG2805@1|root,COG2805@2|Bacteria,1TQ5F@1239|Firmicutes,249H9@186801|Clostridia,25UZ2@186806|Eubacteriaceae	186801|Clostridia	NU	twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
HLKFIFDC_01615	411469.EUBHAL_02415	6.13e-80	245.0	2DKGK@1|root,309ED@2|Bacteria,1UGM0@1239|Firmicutes,25P3S@186801|Clostridia,25Z2H@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01617	411469.EUBHAL_02417	9.56e-208	573.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,25VGY@186806|Eubacteriaceae	186801|Clostridia	G	Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
HLKFIFDC_01618	411469.EUBHAL_02418	8.71e-234	642.0	COG3958@1|root,COG3958@2|Bacteria,1UYH1@1239|Firmicutes,247K7@186801|Clostridia,25V70@186806|Eubacteriaceae	186801|Clostridia	G	Transketolase, pyrimidine binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
HLKFIFDC_01619	411469.EUBHAL_02419	3.42e-176	490.0	COG0274@1|root,COG0274@2|Bacteria,1U9YR@1239|Firmicutes,24CDQ@186801|Clostridia,25ZPR@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	-	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
HLKFIFDC_01620	411469.EUBHAL_02420	5.45e-173	482.0	COG0274@1|root,COG0274@2|Bacteria,1V0GG@1239|Firmicutes,24ESZ@186801|Clostridia,25UZI@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	-	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
HLKFIFDC_01621	411469.EUBHAL_02421	0.0	1044.0	COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,247NR@186801|Clostridia,25UR1@186806|Eubacteriaceae	186801|Clostridia	H	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
HLKFIFDC_01622	411469.EUBHAL_02422	1.23e-164	461.0	COG2188@1|root,COG2188@2|Bacteria,1UYBW@1239|Firmicutes,24N1N@186801|Clostridia,25VIU@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
HLKFIFDC_01623	411469.EUBHAL_02424	3.99e-195	541.0	COG0191@1|root,COG0191@2|Bacteria,1V28V@1239|Firmicutes,24GYP@186801|Clostridia,25WBM@186806|Eubacteriaceae	186801|Clostridia	H	Fructose-bisphosphate aldolase class-II	-	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
HLKFIFDC_01624	411469.EUBHAL_02425	2.5e-230	633.0	COG0613@1|root,COG0613@2|Bacteria,1UH35@1239|Firmicutes,248HV@186801|Clostridia,25V59@186806|Eubacteriaceae	186801|Clostridia	G	DNA polymerase alpha chain like domain	-	-	3.1.3.97,4.1.2.13	ko:K01624,ko:K07053	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R00188,R01068,R01070,R01829,R02568,R11188	RC00078,RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase,PHP
HLKFIFDC_01625	411469.EUBHAL_02426	8.01e-254	696.0	COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,248CR@186801|Clostridia,25V8G@186806|Eubacteriaceae	186801|Clostridia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
HLKFIFDC_01626	411469.EUBHAL_02427	9.04e-98	284.0	COG4506@1|root,COG4506@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF1934)	ywiB	-	-	-	-	-	-	-	-	-	-	-	DUF1934
HLKFIFDC_01627	411469.EUBHAL_02428	5.8e-291	793.0	COG2508@1|root,COG2508@2|Bacteria,1TTA0@1239|Firmicutes,248HN@186801|Clostridia,25X5H@186806|Eubacteriaceae	186801|Clostridia	QT	Purine catabolism regulatory protein-like family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30,PucR
HLKFIFDC_01628	1196322.A370_02993	1.6e-71	230.0	COG0160@1|root,COG0160@2|Bacteria,1VS6F@1239|Firmicutes,24YI0@186801|Clostridia,36ED9@31979|Clostridiaceae	186801|Clostridia	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	gabT	-	2.6.1.19,2.6.1.22	ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iHN637.CLJU_RS10045	Aminotran_3
HLKFIFDC_01629	411469.EUBHAL_02430	5.33e-266	729.0	COG1454@1|root,COG1454@2|Bacteria,1UY3E@1239|Firmicutes,25E9A@186801|Clostridia,25W00@186806|Eubacteriaceae	186801|Clostridia	C	Cytoplasmic, score 9.98	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
HLKFIFDC_01630	411469.EUBHAL_02431	1.33e-301	822.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,248C9@186801|Clostridia,25YEH@186806|Eubacteriaceae	186801|Clostridia	H	Aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
HLKFIFDC_01631	411469.EUBHAL_02432	4.2e-139	393.0	COG1102@1|root,COG1102@2|Bacteria,1V74C@1239|Firmicutes,24EKT@186801|Clostridia	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
HLKFIFDC_01632	411469.EUBHAL_02433	0.0	978.0	COG0531@1|root,COG0531@2|Bacteria,1TQ4K@1239|Firmicutes,25E7A@186801|Clostridia,25ZUM@186806|Eubacteriaceae	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
HLKFIFDC_01633	411469.EUBHAL_02434	1.27e-133	378.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,1V5G6@1239|Firmicutes,24928@186801|Clostridia,25X33@186806|Eubacteriaceae	186801|Clostridia	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
HLKFIFDC_01634	411469.EUBHAL_00717	8.65e-26	97.1	2DXIG@1|root,3455C@2|Bacteria,1VYKU@1239|Firmicutes,2542Y@186801|Clostridia,25Z6G@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01635	411469.EUBHAL_02435	2.26e-54	175.0	2C83V@1|root,2Z99X@2|Bacteria,1TQYC@1239|Firmicutes,24E4W@186801|Clostridia,25WKJ@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF3990)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3990,HTH_3
HLKFIFDC_01636	411469.EUBHAL_02435	3.94e-55	177.0	2C83V@1|root,2Z99X@2|Bacteria,1TQYC@1239|Firmicutes,24E4W@186801|Clostridia,25WKJ@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF3990)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3990,HTH_3
HLKFIFDC_01637	411469.EUBHAL_02436	2.13e-108	313.0	29H8K@1|root,30465@2|Bacteria,1V42R@1239|Firmicutes,24H9W@186801|Clostridia,25YFS@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01638	411469.EUBHAL_02437	7.98e-86	254.0	2AE00@1|root,313SJ@2|Bacteria,1V6FJ@1239|Firmicutes,24JFA@186801|Clostridia,25X4A@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01639	411469.EUBHAL_02438	2.78e-152	429.0	COG0204@1|root,COG0204@2|Bacteria,1UMJA@1239|Firmicutes,249AV@186801|Clostridia,25VQ7@186806|Eubacteriaceae	186801|Clostridia	I	1-acyl-sn-glycerol-3-phosphate acyltransferase	plsC_1	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
HLKFIFDC_01640	411469.EUBHAL_02439	0.0	1047.0	COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia,25UZT@186806|Eubacteriaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
HLKFIFDC_01641	411469.EUBHAL_02327	0.0	978.0	COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,249PY@186801|Clostridia,25VM7@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
HLKFIFDC_01642	411469.EUBHAL_02326	8.07e-173	481.0	COG0564@1|root,COG0564@2|Bacteria,1TX59@1239|Firmicutes,24HTV@186801|Clostridia,25WSE@186806|Eubacteriaceae	186801|Clostridia	J	RNA pseudouridylate synthase	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
HLKFIFDC_01643	411469.EUBHAL_02325	1.82e-173	484.0	COG0745@1|root,COG0745@2|Bacteria,1TPRU@1239|Firmicutes,24843@186801|Clostridia,25VEM@186806|Eubacteriaceae	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	srrA_2	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HLKFIFDC_01644	411469.EUBHAL_02323	7.21e-281	768.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,247J3@186801|Clostridia,25USF@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
HLKFIFDC_01645	411469.EUBHAL_02322	3.49e-89	261.0	COG0853@1|root,COG0853@2|Bacteria,1V6NQ@1239|Firmicutes,24JVN@186801|Clostridia,25W85@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
HLKFIFDC_01646	411469.EUBHAL_02321	5.47e-197	546.0	COG0414@1|root,COG0414@2|Bacteria,1TP7A@1239|Firmicutes,248AN@186801|Clostridia,25URM@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
HLKFIFDC_01647	411469.EUBHAL_02319	1.69e-193	537.0	COG0413@1|root,COG0413@2|Bacteria,1TPZA@1239|Firmicutes,248RR@186801|Clostridia,25V3K@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
HLKFIFDC_01648	411469.EUBHAL_02318	2.16e-204	565.0	COG5495@1|root,COG5495@2|Bacteria,1UZZU@1239|Firmicutes,249YF@186801|Clostridia,25W39@186806|Eubacteriaceae	186801|Clostridia	S	Domain of unknown function (DUF2520)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,F420_oxidored,Rossmann-like
HLKFIFDC_01649	411469.EUBHAL_02317	8.44e-285	778.0	COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,248QF@186801|Clostridia,25V3W@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
HLKFIFDC_01650	411469.EUBHAL_02316	3.24e-307	838.0	COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,2488W@186801|Clostridia,25URW@186806|Eubacteriaceae	186801|Clostridia	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
HLKFIFDC_01651	411469.EUBHAL_02315	3.63e-141	398.0	COG1853@1|root,COG1853@2|Bacteria,1V1EA@1239|Firmicutes,24FWS@186801|Clostridia,25W2D@186806|Eubacteriaceae	186801|Clostridia	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
HLKFIFDC_01652	411469.EUBHAL_02314	4.57e-97	282.0	COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,24JCW@186801|Clostridia,25WUY@186806|Eubacteriaceae	186801|Clostridia	FG	Psort location Cytoplasmic, score	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
HLKFIFDC_01653	411469.EUBHAL_02313	0.0	1304.0	COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,247WH@186801|Clostridia	186801|Clostridia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
HLKFIFDC_01654	411469.EUBHAL_02311	0.0	1215.0	COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,248V6@186801|Clostridia,25VG4@186806|Eubacteriaceae	186801|Clostridia	G	Psort location CytoplasmicMembrane, score	fruA	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
HLKFIFDC_01655	411469.EUBHAL_02310	2.96e-212	587.0	COG1105@1|root,COG1105@2|Bacteria,1TQ36@1239|Firmicutes,249RK@186801|Clostridia,25VK7@186806|Eubacteriaceae	186801|Clostridia	H	Belongs to the carbohydrate kinase PfkB family. LacC subfamily	pfkB	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
HLKFIFDC_01656	411469.EUBHAL_02309	0.0	864.0	COG1653@1|root,COG1653@2|Bacteria,1TPX9@1239|Firmicutes,24DGD@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
HLKFIFDC_01657	411469.EUBHAL_02308	2.48e-151	426.0	COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,24FZX@186801|Clostridia,25ZQZ@186806|Eubacteriaceae	186801|Clostridia	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
HLKFIFDC_01658	411469.EUBHAL_02307	1.82e-316	863.0	COG4585@1|root,COG4585@2|Bacteria,1TQI3@1239|Firmicutes,249R9@186801|Clostridia,25XET@186806|Eubacteriaceae	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K07777	ko02020,map02020	M00478	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3,dCache_1
HLKFIFDC_01659	411469.EUBHAL_02306	1.92e-222	614.0	COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,249ZI@186801|Clostridia	186801|Clostridia	G	COG COG1879 ABC-type sugar transport system, periplasmic component	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
HLKFIFDC_01661	411469.EUBHAL_02304	9.86e-54	168.0	COG1925@1|root,COG1925@2|Bacteria,1TTT4@1239|Firmicutes,25N1G@186801|Clostridia,25XST@186806|Eubacteriaceae	186801|Clostridia	G	PTS HPr component phosphorylation site	-	-	-	ko:K11184	-	-	-	-	ko00000	-	-	-	PTS-HPr
HLKFIFDC_01662	411469.EUBHAL_02303	1.74e-223	616.0	COG1481@1|root,COG1481@2|Bacteria,1TP2X@1239|Firmicutes,2484M@186801|Clostridia,25VF1@186806|Eubacteriaceae	186801|Clostridia	K	May be required for sporulation	whiA	-	-	ko:K09762	-	-	-	-	ko00000	-	-	-	HTH_WhiA,LAGLIDADG_WhiA,WhiA_N
HLKFIFDC_01663	411469.EUBHAL_02302	1.07e-204	566.0	COG1660@1|root,COG1660@2|Bacteria,1TPS4@1239|Firmicutes,248KQ@186801|Clostridia,25UUB@186806|Eubacteriaceae	186801|Clostridia	S	Displays ATPase and GTPase activities	yvcJ	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
HLKFIFDC_01664	411469.EUBHAL_02301	2.48e-212	590.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,247IU@186801|Clostridia,25UUJ@186806|Eubacteriaceae	186801|Clostridia	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
HLKFIFDC_01665	411469.EUBHAL_02299	3.79e-222	616.0	COG1493@1|root,COG1493@2|Bacteria,1TP5Z@1239|Firmicutes,24999@186801|Clostridia,25UYM@186806|Eubacteriaceae	186801|Clostridia	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
HLKFIFDC_01666	411469.EUBHAL_02297	0.0	1231.0	COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,247TQ@186801|Clostridia,25VJV@186806|Eubacteriaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
HLKFIFDC_01667	411469.EUBHAL_02296	0.0	1190.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia,25UYJ@186806|Eubacteriaceae	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
HLKFIFDC_01668	411469.EUBHAL_02295	2.32e-196	544.0	COG0489@1|root,COG0489@2|Bacteria,1TQ34@1239|Firmicutes,24817@186801|Clostridia,25VN4@186806|Eubacteriaceae	186801|Clostridia	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	-	-	-	-	-	-	-	-	-	ParA
HLKFIFDC_01669	411469.EUBHAL_02294	1.46e-153	434.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,248AR@186801|Clostridia,25W6C@186806|Eubacteriaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
HLKFIFDC_01670	411469.EUBHAL_02293	2.15e-260	714.0	COG1454@1|root,COG1454@2|Bacteria,1UGWW@1239|Firmicutes,24A5G@186801|Clostridia,25VNW@186806|Eubacteriaceae	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
HLKFIFDC_01671	411469.EUBHAL_02292	2.15e-235	647.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,248PB@186801|Clostridia,25USZ@186806|Eubacteriaceae	186801|Clostridia	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
HLKFIFDC_01672	411469.EUBHAL_02291	0.0	2278.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,25V2U@186806|Eubacteriaceae	186801|Clostridia	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
HLKFIFDC_01673	411469.EUBHAL_02290	1.96e-277	758.0	COG1775@1|root,COG1775@2|Bacteria,1TPEF@1239|Firmicutes,24A11@186801|Clostridia,25V17@186806|Eubacteriaceae	186801|Clostridia	E	2-hydroxyglutaryl-CoA dehydratase, D-component	yjiM	-	-	-	-	-	-	-	-	-	-	-	HGD-D
HLKFIFDC_01674	411469.EUBHAL_02289	4.6e-169	473.0	COG1349@1|root,COG1349@2|Bacteria,1TNYH@1239|Firmicutes,24BT5@186801|Clostridia,25ZNQ@186806|Eubacteriaceae	186801|Clostridia	K	DeoR C terminal sensor domain	-	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
HLKFIFDC_01675	553973.CLOHYLEM_06653	6.07e-10	59.7	2DNCY@1|root,32WUK@2|Bacteria,1VDD9@1239|Firmicutes,24Q9T@186801|Clostridia,220TN@1506553|Lachnoclostridium	186801|Clostridia	S	Protein of unknown function (DUF2877)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2877
HLKFIFDC_01676	411469.EUBHAL_02287	0.0	1342.0	COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,2480C@186801|Clostridia,25VK6@186806|Eubacteriaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
HLKFIFDC_01677	411469.EUBHAL_02286	3.44e-122	348.0	COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,247XN@186801|Clostridia,25W2U@186806|Eubacteriaceae	186801|Clostridia	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
HLKFIFDC_01678	411469.EUBHAL_00706	6.58e-226	622.0	COG0561@1|root,COG0561@2|Bacteria,1V1JB@1239|Firmicutes,24AY8@186801|Clostridia,25ZQY@186806|Eubacteriaceae	186801|Clostridia	S	Sucrose-6F-phosphate phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
HLKFIFDC_01679	411469.EUBHAL_00705	9.13e-262	717.0	COG1118@1|root,COG1118@2|Bacteria,1UI1E@1239|Firmicutes,25EAE@186801|Clostridia,25VJJ@186806|Eubacteriaceae	186801|Clostridia	P	ATPases associated with a variety of cellular activities	modC	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran
HLKFIFDC_01680	411469.EUBHAL_00704	4.78e-149	420.0	COG4149@1|root,COG4149@2|Bacteria,1TRNA@1239|Firmicutes,24BR9@186801|Clostridia,25WH2@186806|Eubacteriaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	modB	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
HLKFIFDC_01681	411469.EUBHAL_00703	1.27e-174	489.0	COG0725@1|root,COG0725@2|Bacteria,1U9U3@1239|Firmicutes,249VA@186801|Clostridia,25WJQ@186806|Eubacteriaceae	186801|Clostridia	P	Bacterial extracellular solute-binding protein	modA	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	iHN637.CLJU_RS12820	SBP_bac_11
HLKFIFDC_01682	411469.EUBHAL_00702	1e-226	627.0	COG1910@1|root,COG1910@2|Bacteria,1TRH3@1239|Firmicutes,24ATZ@186801|Clostridia,25W1E@186806|Eubacteriaceae	186801|Clostridia	P	Helix-turn-helix domain	-	-	-	ko:K07219	-	-	-	-	ko00000	-	-	-	HTH_17,PBP_like
HLKFIFDC_01683	411469.EUBHAL_00701	2.99e-316	859.0	COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,247X7@186801|Clostridia,25VS8@186806|Eubacteriaceae	186801|Clostridia	E	diaminopimelate decarboxylase	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
HLKFIFDC_01684	411469.EUBHAL_00700	1.72e-163	459.0	COG1378@1|root,COG1378@2|Bacteria,1V2DD@1239|Firmicutes,24BVS@186801|Clostridia,25YNY@186806|Eubacteriaceae	186801|Clostridia	K	Sugar-specific transcriptional regulator TrmB	-	-	-	-	-	-	-	-	-	-	-	-	Regulator_TrmB,TrmB
HLKFIFDC_01685	411469.EUBHAL_00281	1.13e-126	361.0	COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,24JRN@186801|Clostridia,25WJI@186806|Eubacteriaceae	186801|Clostridia	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
HLKFIFDC_01686	411469.EUBHAL_00279	3.63e-288	787.0	COG2230@1|root,COG2230@2|Bacteria,1TSG4@1239|Firmicutes,248GV@186801|Clostridia,25V3G@186806|Eubacteriaceae	186801|Clostridia	M	Mycolic acid cyclopropane synthetase	cfa	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
HLKFIFDC_01687	411469.EUBHAL_00276	0.0	1014.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,2490X@186801|Clostridia,25V9Y@186806|Eubacteriaceae	186801|Clostridia	E	glutamate synthase	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
HLKFIFDC_01688	411469.EUBHAL_00275	0.0	3002.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1TQ0B@1239|Firmicutes,248IB@186801|Clostridia,25UVR@186806|Eubacteriaceae	186801|Clostridia	E	glutamate synthase	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
HLKFIFDC_01690	411470.RUMGNA_01788	7.88e-181	526.0	COG2865@1|root,COG2865@2|Bacteria,1TSPK@1239|Firmicutes,24B9Q@186801|Clostridia,3XZHR@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4
HLKFIFDC_01691	411469.EUBHAL_00273	0.0	2360.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,25USH@186806|Eubacteriaceae	186801|Clostridia	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
HLKFIFDC_01692	411469.EUBHAL_00271	3.75e-93	273.0	COG1989@1|root,COG1989@2|Bacteria,1VEVI@1239|Firmicutes	1239|Firmicutes	NOU	Type IV leader peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_A24
HLKFIFDC_01693	411469.EUBHAL_00270	1.15e-314	859.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,25VM4@186806|Eubacteriaceae	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
HLKFIFDC_01694	411469.EUBHAL_00269	6.36e-54	168.0	2E9QS@1|root,333X3@2|Bacteria,1VHZY@1239|Firmicutes,24S7Q@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01695	411469.EUBHAL_00267	8.47e-317	867.0	COG1559@1|root,COG1559@2|Bacteria,1TS48@1239|Firmicutes,2493B@186801|Clostridia,25VD2@186806|Eubacteriaceae	186801|Clostridia	M	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
HLKFIFDC_01696	411469.EUBHAL_00266	6.24e-219	605.0	COG1670@1|root,COG1670@2|Bacteria,1V4FZ@1239|Firmicutes,24PF4@186801|Clostridia	186801|Clostridia	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
HLKFIFDC_01697	411459.RUMOBE_01118	2.58e-49	162.0	COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,24HF9@186801|Clostridia,3XZWB@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
HLKFIFDC_01706	411461.DORFOR_01144	7.44e-80	262.0	COG1475@1|root,COG1475@2|Bacteria,1UXYV@1239|Firmicutes,24F88@186801|Clostridia	186801|Clostridia	K	Belongs to the ParB family	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
HLKFIFDC_01707	411459.RUMOBE_01110	4.46e-23	92.0	2CIZQ@1|root,33BCN@2|Bacteria,1VXAK@1239|Firmicutes,24VGW@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01710	445972.ANACOL_01830	1.3e-120	355.0	COG4227@1|root,COG4227@2|Bacteria,1TQN4@1239|Firmicutes,2482H@186801|Clostridia,3WNCC@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4316,Peptidase_M78,YodL
HLKFIFDC_01711	411459.RUMOBE_01107	1.83e-256	705.0	2F7JT@1|root,3400E@2|Bacteria,1VN25@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01720	1123075.AUDP01000031_gene2144	2.29e-10	61.2	COG2963@1|root,COG2963@2|Bacteria,1UWW1@1239|Firmicutes,25KV2@186801|Clostridia,3WR6W@541000|Ruminococcaceae	186801|Clostridia	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
HLKFIFDC_01722	476272.RUMHYD_01764	1.17e-11	65.1	2E3F3@1|root,32YE0@2|Bacteria,1VJVH@1239|Firmicutes,24TV2@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01727	411490.ANACAC_00704	1.64e-12	63.5	2E4T7@1|root,32ZMK@2|Bacteria,1VGFK@1239|Firmicutes,24RBQ@186801|Clostridia	186801|Clostridia	S	Putative lactococcus lactis phage r1t holin	-	-	-	-	-	-	-	-	-	-	-	-	Phage_r1t_holin
HLKFIFDC_01729	357809.Cphy_3715	5.17e-50	164.0	COG4905@1|root,COG4905@2|Bacteria,1VA0H@1239|Firmicutes,24NAK@186801|Clostridia,2210T@1506553|Lachnoclostridium	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.26	-	-	-	-	-	-	-	-	-	-	-	-	ABC_trans_CmpB
HLKFIFDC_01730	608534.GCWU000341_02274	2.9e-29	116.0	2E905@1|root,3339K@2|Bacteria,1VEY9@1239|Firmicutes,24RWX@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01733	1235793.C809_02277	3.77e-38	132.0	2EAW6@1|root,30MCH@2|Bacteria,1U2JW@1239|Firmicutes,259QN@186801|Clostridia,27PID@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Phage tail-collar fibre protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3751
HLKFIFDC_01735	411459.RUMOBE_01070	1.06e-188	535.0	COG3299@1|root,COG3299@2|Bacteria,1TQZU@1239|Firmicutes,249WP@186801|Clostridia	186801|Clostridia	S	baseplate J-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
HLKFIFDC_01736	411459.RUMOBE_01069	6.1e-46	153.0	COG3628@1|root,COG3628@2|Bacteria	2|Bacteria	-	-	xkdS	-	-	-	-	-	-	-	-	-	-	-	DUF2634
HLKFIFDC_01738	411459.RUMOBE_01067	5.38e-149	431.0	COG4193@1|root,COG4193@2|Bacteria,1VAT1@1239|Firmicutes	1239|Firmicutes	G	NLP P60 protein	xkdQ	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01739	411459.RUMOBE_01066	3.72e-65	209.0	COG1652@1|root,COG1652@2|Bacteria	2|Bacteria	S	positive regulation of growth rate	-	-	-	ko:K02030,ko:K16291	-	M00236	-	-	ko00000,ko00002,ko01002,ko01011,ko02000	3.A.1.3	-	-	LysM,SBP_bac_3,SH3_3
HLKFIFDC_01740	411459.RUMOBE_01065	0.0	1102.0	COG5283@1|root,COG5283@2|Bacteria,1UHQM@1239|Firmicutes,25E9Q@186801|Clostridia	186801|Clostridia	M	phage tail tape measure protein	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23,PhageMin_Tail
HLKFIFDC_01744	411459.RUMOBE_01062	1.51e-239	668.0	28IGV@1|root,2Z8I6@2|Bacteria,1TP1Y@1239|Firmicutes,24AS0@186801|Clostridia	186801|Clostridia	S	PFAM Phage tail sheath protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_sheath_1,Phage_sheath_1C,Phage_sheath_1N
HLKFIFDC_01747	411459.RUMOBE_01058	5.66e-88	261.0	2EFQM@1|root,339GM@2|Bacteria,1VIMT@1239|Firmicutes,253HR@186801|Clostridia	186801|Clostridia	S	Bacteriophage HK97-gp10, putative tail-component	-	-	-	-	-	-	-	-	-	-	-	-	HK97-gp10_like
HLKFIFDC_01749	411459.RUMOBE_01056	1.4e-50	164.0	2ESBD@1|root,33JW4@2|Bacteria,1VP51@1239|Firmicutes	1239|Firmicutes	S	Protein of unknown function (DUF3199)	yqbG	-	-	-	-	-	-	-	-	-	-	-	DUF3199
HLKFIFDC_01752	411459.RUMOBE_01053	9.06e-192	536.0	COG4653@1|root,COG4653@2|Bacteria,1V0XG@1239|Firmicutes	1239|Firmicutes	S	Phage capsid family	xkdG	-	-	-	-	-	-	-	-	-	-	-	Phage_capsid
HLKFIFDC_01753	411459.RUMOBE_01052	3.8e-182	523.0	COG0338@1|root,COG0338@2|Bacteria,1V1FT@1239|Firmicutes,250FC@186801|Clostridia	186801|Clostridia	L	Putative phage serine protease XkdF	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S78_2
HLKFIFDC_01754	411459.RUMOBE_01051	1.09e-177	503.0	COG2369@1|root,COG2369@2|Bacteria,1V2XJ@1239|Firmicutes,2535G@186801|Clostridia	186801|Clostridia	S	Phage Mu protein F like protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_Mu_F
HLKFIFDC_01755	411459.RUMOBE_01050	5.56e-260	726.0	COG5518@1|root,COG5518@2|Bacteria,1TT5R@1239|Firmicutes,24XUM@186801|Clostridia	186801|Clostridia	S	Bacteriophage capsid portal protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01756	411459.RUMOBE_01049	3.53e-311	851.0	COG0507@1|root,COG0507@2|Bacteria,1TQWH@1239|Firmicutes,24A8I@186801|Clostridia	186801|Clostridia	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01757	173707.Q938L4_9CAUD	1.41e-10	63.9	4QBA4@10239|Viruses,4QX0W@35237|dsDNA viruses  no RNA stage,4QU0X@28883|Caudovirales,4QM8F@10699|Siphoviridae	10699|Siphoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01758	411459.RUMOBE_01047	2.67e-145	419.0	COG0535@1|root,COG0535@2|Bacteria,1UY09@1239|Firmicutes,24D8R@186801|Clostridia	186801|Clostridia	S	Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
HLKFIFDC_01761	411459.RUMOBE_01044	3.23e-121	352.0	COG1475@1|root,COG1475@2|Bacteria,1TPHP@1239|Firmicutes,249MR@186801|Clostridia,3XZ5Y@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase,ParBc
HLKFIFDC_01762	411459.RUMOBE_01043	1.09e-60	191.0	2DS6F@1|root,33ESA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1492
HLKFIFDC_01763	610130.Closa_0723	2.7e-18	77.8	294B7@1|root,2ZRRE@2|Bacteria,1W6D4@1239|Firmicutes,24W5H@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01767	411459.RUMOBE_01038	1.11e-63	197.0	COG4570@1|root,COG4570@2|Bacteria,1VF2H@1239|Firmicutes,25IC3@186801|Clostridia,3Y26N@572511|Blautia	186801|Clostridia	L	COG COG4570 Holliday junction resolvase	rusA	-	-	-	-	-	-	-	-	-	-	-	RusA
HLKFIFDC_01768	1497679.EP56_07600	2.1e-10	61.2	2EC8I@1|root,33670@2|Bacteria,1VENI@1239|Firmicutes,4HR98@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01769	395964.KE386496_gene2146	3.46e-07	52.4	COG1476@1|root,COG1476@2|Bacteria,1N1NK@1224|Proteobacteria,2UBVZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HLKFIFDC_01770	411459.RUMOBE_01035	3.08e-149	426.0	COG1484@1|root,COG1484@2|Bacteria,1TPZX@1239|Firmicutes,248F0@186801|Clostridia,3XZBX@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
HLKFIFDC_01771	411459.RUMOBE_01034	1.92e-95	286.0	COG3935@1|root,COG3935@2|Bacteria,1TQT6@1239|Firmicutes,24I78@186801|Clostridia,3Y0JU@572511|Blautia	186801|Clostridia	L	DnaD domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01772	411459.RUMOBE_01032	2.18e-291	805.0	COG0433@1|root,COG0433@2|Bacteria,1TPQN@1239|Firmicutes,249YI@186801|Clostridia,3Y1HW@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853,DUF87,HAS-barrel
HLKFIFDC_01773	411459.RUMOBE_01031	5.66e-152	429.0	COG1074@1|root,COG1074@2|Bacteria,1V1UQ@1239|Firmicutes,24CGP@186801|Clostridia,3Y1HR@572511|Blautia	186801|Clostridia	L	PDDEXK-like domain of unknown function (DUF3799)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3799
HLKFIFDC_01774	411459.RUMOBE_01030	3.48e-149	426.0	28KIJ@1|root,2ZA3S@2|Bacteria,1TSCG@1239|Firmicutes,24DNK@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01777	411459.RUMOBE_01027	2.31e-54	177.0	COG3773@1|root,COG3773@2|Bacteria,1UFDA@1239|Firmicutes,24QV4@186801|Clostridia	186801|Clostridia	M	Cell Wall Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_2
HLKFIFDC_01779	411459.RUMOBE_01025	7.04e-72	221.0	COG1813@1|root,COG1813@2|Bacteria,1V6NP@1239|Firmicutes,25CXJ@186801|Clostridia	186801|Clostridia	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01780	411459.RUMOBE_01024	2.13e-30	108.0	298NB@1|root,2ZVSX@2|Bacteria,1W4VN@1239|Firmicutes,254UN@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01781	411459.RUMOBE_01022	1.52e-41	139.0	COG1476@1|root,COG1476@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	espR	GO:0002791,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009605,GO:0009607,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0032879,GO:0032880,GO:0032991,GO:0032993,GO:0042802,GO:0043207,GO:0043565,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050708,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051049,GO:0051171,GO:0051223,GO:0051252,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070201,GO:0071944,GO:0075136,GO:0080090,GO:0090087,GO:0097159,GO:1901363,GO:1903506,GO:1903530,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	HTH_3
HLKFIFDC_01783	411459.RUMOBE_01020	1.08e-315	872.0	COG1961@1|root,COG1961@2|Bacteria,1TS5B@1239|Firmicutes,248MZ@186801|Clostridia,3Y0NN@572511|Blautia	186801|Clostridia	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
HLKFIFDC_01784	411469.EUBHAL_00123	2.56e-249	684.0	COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,247NT@186801|Clostridia,25UV7@186806|Eubacteriaceae	186801|Clostridia	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
HLKFIFDC_01785	411469.EUBHAL_00122	0.0	1611.0	COG0072@1|root,COG0072@2|Bacteria,1TP98@1239|Firmicutes,248BJ@186801|Clostridia,25UVH@186806|Eubacteriaceae	186801|Clostridia	J	phenylalanyl-tRNA synthetase (beta subunit)	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA-synt_2d,tRNA_bind
HLKFIFDC_01786	411469.EUBHAL_00121	1.37e-247	679.0	COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,2486E@186801|Clostridia,25VAC@186806|Eubacteriaceae	186801|Clostridia	J	Phenylalanyl-tRNA synthetase alpha subunit	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
HLKFIFDC_01787	411469.EUBHAL_00120	3.17e-149	420.0	COG1434@1|root,COG1434@2|Bacteria,1V32X@1239|Firmicutes,24ATY@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
HLKFIFDC_01788	411469.EUBHAL_00119	2.97e-219	606.0	COG1295@1|root,COG1295@2|Bacteria,1U7HM@1239|Firmicutes,24A2Q@186801|Clostridia,25WIZ@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the UPF0761 family	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
HLKFIFDC_01789	411469.EUBHAL_00118	2.7e-145	409.0	2943S@1|root,2ZRIE@2|Bacteria,1V3J6@1239|Firmicutes,24HEP@186801|Clostridia,25WD5@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	KatE	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01790	411469.EUBHAL_00116	3.05e-227	627.0	COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,248Q5@186801|Clostridia,25VN8@186806|Eubacteriaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
HLKFIFDC_01791	411469.EUBHAL_00115	9.2e-101	292.0	COG0720@1|root,COG0720@2|Bacteria,1VAJX@1239|Firmicutes,24JS9@186801|Clostridia,25WPS@186806|Eubacteriaceae	186801|Clostridia	H	6-pyruvoyl tetrahydropterin synthase	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
HLKFIFDC_01792	411469.EUBHAL_00114	5.49e-163	455.0	COG0602@1|root,COG0602@2|Bacteria,1TQ58@1239|Firmicutes,2499R@186801|Clostridia,25W1R@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_12,Fer4_14,Radical_SAM
HLKFIFDC_01793	411469.EUBHAL_00113	2.17e-134	381.0	COG0302@1|root,COG0302@2|Bacteria,1TRNM@1239|Firmicutes,24867@186801|Clostridia,25W67@186806|Eubacteriaceae	186801|Clostridia	H	GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
HLKFIFDC_01794	411469.EUBHAL_00112	6.68e-164	457.0	COG0603@1|root,COG0603@2|Bacteria,1TP4Z@1239|Firmicutes,2497A@186801|Clostridia,25VE2@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
HLKFIFDC_01795	411469.EUBHAL_01502	3e-157	442.0	COG3341@1|root,COG3341@2|Bacteria,1UIS0@1239|Firmicutes,25EQZ@186801|Clostridia,25ZK3@186806|Eubacteriaceae	186801|Clostridia	L	Caulimovirus viroplasmin	rnhA	-	-	ko:K06993	-	-	-	-	ko00000	-	-	-	Cauli_VI,RNase_H
HLKFIFDC_01796	411469.EUBHAL_01501	5.23e-160	448.0	COG2964@1|root,COG2964@2|Bacteria,1V2VD@1239|Firmicutes,24GH7@186801|Clostridia,25WMD@186806|Eubacteriaceae	186801|Clostridia	S	YheO-like PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_22,PAS_6
HLKFIFDC_01798	411469.EUBHAL_01498	0.0	1254.0	2EHRG@1|root,33BH8@2|Bacteria,1VMCE@1239|Firmicutes,25D54@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01799	411469.EUBHAL_01497	1.15e-147	415.0	COG3757@1|root,COG3757@2|Bacteria	2|Bacteria	M	lysozyme activity	XK27_00880	-	3.5.1.28	ko:K01447,ko:K07273	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Glyco_hydro_25
HLKFIFDC_01800	411469.EUBHAL_01672	4.08e-85	259.0	COG5263@1|root,COG5263@2|Bacteria	2|Bacteria	S	dextransucrase activity	-	-	3.2.1.78	ko:K19355	ko00051,map00051	-	R01332	RC00467	ko00000,ko00001,ko01000	-	-	-	DUF1735,SLH
HLKFIFDC_01801	411469.EUBHAL_01671	4.66e-143	409.0	2EIHX@1|root,33C99@2|Bacteria,1VUXS@1239|Firmicutes,24WII@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01802	411469.EUBHAL_01670	1.28e-298	813.0	COG0624@1|root,COG0624@2|Bacteria,1TPMJ@1239|Firmicutes,24BEY@186801|Clostridia,25W8U@186806|Eubacteriaceae	186801|Clostridia	E	Peptidase dimerisation domain	-	-	3.5.1.16,3.5.1.18	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00669,R02734,R09107	RC00064,RC00090,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
HLKFIFDC_01803	411469.EUBHAL_01669	0.0	944.0	COG0044@1|root,COG0044@2|Bacteria,1TP8C@1239|Firmicutes,249W6@186801|Clostridia,25VQD@186806|Eubacteriaceae	186801|Clostridia	F	Amidohydrolase family	hydA	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
HLKFIFDC_01804	411469.EUBHAL_01668	8.7e-83	245.0	COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,24J8Y@186801|Clostridia,25WVB@186806|Eubacteriaceae	186801|Clostridia	J	Psort location Cytoplasmic, score	TdcF	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
HLKFIFDC_01805	411469.EUBHAL_01667	2.26e-217	600.0	COG0549@1|root,COG0549@2|Bacteria,1TP9H@1239|Firmicutes,2482W@186801|Clostridia,25V49@186806|Eubacteriaceae	186801|Clostridia	E	carbamate kinase	arcC	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
HLKFIFDC_01806	411469.EUBHAL_01666	1.28e-296	808.0	COG0078@1|root,COG0078@2|Bacteria,1TNY4@1239|Firmicutes,249P4@186801|Clostridia,25VGX@186806|Eubacteriaceae	186801|Clostridia	E	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	ygeW	-	-	-	-	-	-	-	-	-	-	-	OTCace,OTCace_N
HLKFIFDC_01807	411469.EUBHAL_01665	0.0	945.0	COG0624@1|root,COG0624@2|Bacteria,1TR99@1239|Firmicutes,248DC@186801|Clostridia,25UT4@186806|Eubacteriaceae	186801|Clostridia	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
HLKFIFDC_01808	411469.EUBHAL_01664	1.1e-299	816.0	COG1171@1|root,COG1171@2|Bacteria,1TR70@1239|Firmicutes,2485T@186801|Clostridia,25VGS@186806|Eubacteriaceae	186801|Clostridia	E	Pyridoxal-phosphate dependent enzyme	dpaL	-	4.3.1.15	ko:K01751	-	-	-	-	ko00000,ko01000	-	-	-	PALP
HLKFIFDC_01809	411469.EUBHAL_01663	8.98e-225	619.0	COG2005@1|root,COG2068@1|root,COG2005@2|Bacteria,COG2068@2|Bacteria,1VFW6@1239|Firmicutes,24QTV@186801|Clostridia,25XEN@186806|Eubacteriaceae	186801|Clostridia	S	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	ko:K02019	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,NTP_transf_3
HLKFIFDC_01810	411469.EUBHAL_01981	0.0	1732.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,25VMN@186806|Eubacteriaceae	186801|Clostridia	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	mop	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
HLKFIFDC_01811	411469.EUBHAL_01982	6.41e-89	265.0	COG2878@1|root,COG2878@2|Bacteria,1TQGD@1239|Firmicutes,24904@186801|Clostridia,25VDB@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	rnfB	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4,Fer4_13,Fer4_4,Fer4_9
HLKFIFDC_01812	411469.EUBHAL_01983	0.0	1977.0	COG0493@1|root,COG1145@1|root,COG0493@2|Bacteria,COG1145@2|Bacteria,1TPR4@1239|Firmicutes,248TM@186801|Clostridia,25W02@186806|Eubacteriaceae	186801|Clostridia	C	FAD binding domain	-	-	1.97.1.9	ko:K12527	ko00450,map00450	-	R07229	RC02420	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2,Pyr_redox_3
HLKFIFDC_01813	411469.EUBHAL_01984	0.0	913.0	COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,248IX@186801|Clostridia,25V58@186806|Eubacteriaceae	186801|Clostridia	F	Amidohydrolase family	ssnA	-	3.5.4.40	ko:K20810	ko00130,ko01110,map00130,map01110	-	R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
HLKFIFDC_01814	411469.EUBHAL_01985	1.06e-149	421.0	COG2964@1|root,COG2964@2|Bacteria,1TSI2@1239|Firmicutes,249X6@186801|Clostridia,25YG5@186806|Eubacteriaceae	186801|Clostridia	S	YheO-like PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_22,PAS_6
HLKFIFDC_01815	411469.EUBHAL_01986	3.78e-306	837.0	COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,25CEM@186801|Clostridia,25UXU@186806|Eubacteriaceae	186801|Clostridia	F	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K03458	-	-	-	-	ko00000	2.A.40	-	-	Xan_ur_permease
HLKFIFDC_01816	411469.EUBHAL_01987	2.67e-131	372.0	COG1954@1|root,COG1954@2|Bacteria,1V4IE@1239|Firmicutes,24I8Z@186801|Clostridia,25WCP@186806|Eubacteriaceae	186801|Clostridia	K	Glycerol-3-phosphate responsive antiterminator	-	-	-	ko:K02443	-	-	-	-	ko00000,ko03000	-	-	-	G3P_antiterm
HLKFIFDC_01817	411469.EUBHAL_01988	0.0	1018.0	COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,247NR@186801|Clostridia,25W0C@186806|Eubacteriaceae	186801|Clostridia	H	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.53	ko:K00880	ko00040,ko00053,map00040,map00053	-	R01901,R07127	RC00002,RC00017,RC00538	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
HLKFIFDC_01818	411469.EUBHAL_01989	7.26e-209	577.0	COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,25C7M@186801|Clostridia,25Y7Z@186806|Eubacteriaceae	186801|Clostridia	H	Fructose-bisphosphate aldolase class-II	-	-	-	-	-	-	-	-	-	-	-	-	F_bP_aldolase
HLKFIFDC_01819	411469.EUBHAL_01990	5.21e-177	493.0	COG1028@1|root,COG1028@2|Bacteria,1TRND@1239|Firmicutes,2490V@186801|Clostridia,25VTF@186806|Eubacteriaceae	186801|Clostridia	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
HLKFIFDC_01820	411469.EUBHAL_01991	1.26e-285	781.0	COG5441@1|root,COG5441@2|Bacteria,1TQ3W@1239|Firmicutes,24A9D@186801|Clostridia,25W0H@186806|Eubacteriaceae	186801|Clostridia	S	Uncharacterised protein family (UPF0261)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0261
HLKFIFDC_01821	411469.EUBHAL_01992	5.29e-197	545.0	COG1234@1|root,COG1234@2|Bacteria,1TPSW@1239|Firmicutes,249RR@186801|Clostridia,25V4U@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
HLKFIFDC_01822	411469.EUBHAL_01993	5.71e-53	166.0	COG1396@1|root,COG1396@2|Bacteria,1VN7C@1239|Firmicutes,24X6U@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HLKFIFDC_01823	411469.EUBHAL_01994	9.88e-69	210.0	COG1974@1|root,COG1974@2|Bacteria,1VNN1@1239|Firmicutes,25PST@186801|Clostridia,25Z0X@186806|Eubacteriaceae	186801|Clostridia	KT	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01824	411469.EUBHAL_01995	1.37e-45	147.0	COG2026@1|root,COG2026@2|Bacteria,1VCJ7@1239|Firmicutes,24Q49@186801|Clostridia,25XS6@186806|Eubacteriaceae	186801|Clostridia	DJ	Addiction module toxin, RelE StbE family	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
HLKFIFDC_01825	411469.EUBHAL_01996	1.57e-46	149.0	2EVPB@1|root,33P3A@2|Bacteria,1VN4M@1239|Firmicutes,24W8T@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01826	272563.CD630_29510	7.59e-09	55.1	COG2856@1|root,COG2856@2|Bacteria,1V4N6@1239|Firmicutes,24JDG@186801|Clostridia	186801|Clostridia	E	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
HLKFIFDC_01828	411469.EUBHAL_02001	9.61e-207	575.0	COG0172@1|root,COG0172@2|Bacteria,1TPSA@1239|Firmicutes,24CTC@186801|Clostridia,25WRY@186806|Eubacteriaceae	186801|Clostridia	J	T5orf172	-	-	-	-	-	-	-	-	-	-	-	-	DUF4041,T5orf172
HLKFIFDC_01829	411469.EUBHAL_02003	6.93e-164	464.0	COG4748@1|root,COG4748@2|Bacteria,1TQE6@1239|Firmicutes,24AIE@186801|Clostridia,25W45@186806|Eubacteriaceae	186801|Clostridia	S	Type I restriction enzyme R protein N terminus (HSDR_N)	-	-	-	ko:K07504	-	-	-	-	ko00000	-	-	-	HSDR_N,HSDR_N_2
HLKFIFDC_01830	428125.CLOLEP_01345	9.68e-148	431.0	COG0582@1|root,COG0582@2|Bacteria,1TSN5@1239|Firmicutes,248E3@186801|Clostridia,3WHUU@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase,zinc_ribbon_2
HLKFIFDC_01831	411469.EUBHAL_02006	1.3e-239	659.0	2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia,25VPV@186806|Eubacteriaceae	186801|Clostridia	S	Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	GGGtGRT
HLKFIFDC_01832	411469.EUBHAL_02007	1.19e-168	471.0	COG0822@1|root,COG0822@2|Bacteria,1TQEQ@1239|Firmicutes,248ID@186801|Clostridia,25V1D@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	NifU_N
HLKFIFDC_01833	411469.EUBHAL_01896	8.28e-173	487.0	2EFM6@1|root,339DD@2|Bacteria,1VJGN@1239|Firmicutes,24TDK@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01834	411469.EUBHAL_01895	2.58e-146	414.0	COG1207@1|root,COG1207@2|Bacteria,1UH6D@1239|Firmicutes,25PV6@186801|Clostridia,25VNM@186806|Eubacteriaceae	186801|Clostridia	M	Bacterial transferase hexapeptide	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
HLKFIFDC_01835	411469.EUBHAL_01893	0.0	1417.0	COG0550@1|root,COG0550@2|Bacteria,1TPJD@1239|Firmicutes,24810@186801|Clostridia,25V1M@186806|Eubacteriaceae	186801|Clostridia	L	Bacterial DNA topoisomerase I DNA-binding domain	topB1	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
HLKFIFDC_01836	411469.EUBHAL_01891	4.89e-153	429.0	COG1139@1|root,COG1139@2|Bacteria,1TP90@1239|Firmicutes,249B6@186801|Clostridia,25W6X@186806|Eubacteriaceae	186801|Clostridia	C	LUD domain	-	-	-	-	-	-	-	-	-	-	-	-	LUD_dom
HLKFIFDC_01837	411469.EUBHAL_01890	0.0	1177.0	COG0642@1|root,COG0642@2|Bacteria,1UYZX@1239|Firmicutes,25E9T@186801|Clostridia,25ZJZ@186806|Eubacteriaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C,HATPase_c,HisKA,PilJ,Response_reg,SBP_bac_3
HLKFIFDC_01838	411469.EUBHAL_01889	2.39e-304	830.0	COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,248W5@186801|Clostridia,25V9H@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
HLKFIFDC_01839	411469.EUBHAL_01888	0.0	892.0	COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,247TA@186801|Clostridia,25UVU@186806|Eubacteriaceae	186801|Clostridia	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
HLKFIFDC_01840	411469.EUBHAL_01887	2.12e-88	261.0	2AU16@1|root,31JM9@2|Bacteria,1V6CJ@1239|Firmicutes,24JBF@186801|Clostridia,25X56@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01841	411469.EUBHAL_01886	0.0	1250.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,25VNK@186806|Eubacteriaceae	186801|Clostridia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpC	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
HLKFIFDC_01842	411469.EUBHAL_01884	3.47e-81	241.0	COG1725@1|root,COG1725@2|Bacteria,1V743@1239|Firmicutes,24J7Q@186801|Clostridia,25WXV@186806|Eubacteriaceae	186801|Clostridia	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
HLKFIFDC_01843	411469.EUBHAL_02717	3.19e-111	320.0	COG1546@1|root,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,249WC@186801|Clostridia,25VBH@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
HLKFIFDC_01844	411469.EUBHAL_02716	1.73e-123	353.0	COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,24J7Y@186801|Clostridia,25W8B@186806|Eubacteriaceae	186801|Clostridia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
HLKFIFDC_01845	411469.EUBHAL_02715	0.0	910.0	COG0621@1|root,COG0621@2|Bacteria,1TP2W@1239|Firmicutes,2487D@186801|Clostridia,25UQB@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
HLKFIFDC_01846	411469.EUBHAL_02714	1.96e-200	555.0	COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,248DB@186801|Clostridia,25V5T@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
HLKFIFDC_01847	411469.EUBHAL_02713	0.0	1772.0	COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,247KM@186801|Clostridia,25UYI@186806|Eubacteriaceae	186801|Clostridia	D	FtsK SpoIIIE family protein	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
HLKFIFDC_01848	411469.EUBHAL_02712	2.11e-154	434.0	COG0740@1|root,COG0740@2|Bacteria,1TPX2@1239|Firmicutes,249QX@186801|Clostridia,25VH4@186806|Eubacteriaceae	186801|Clostridia	OU	COG0740 Protease subunit of ATP-dependent Clp proteases	tepA	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
HLKFIFDC_01849	411469.EUBHAL_02711	2.2e-172	481.0	COG0834@1|root,COG0834@2|Bacteria	2|Bacteria	ET	amino acid transport	fliY	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
HLKFIFDC_01850	411469.EUBHAL_02710	0.0	901.0	COG0286@1|root,COG0286@2|Bacteria,1TPGZ@1239|Firmicutes,247RY@186801|Clostridia	186801|Clostridia	V	type I restriction-modification system	hsdM	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
HLKFIFDC_01851	411469.EUBHAL_02709	8.07e-131	372.0	COG0732@1|root,COG0732@2|Bacteria,1VDI7@1239|Firmicutes,24WRY@186801|Clostridia,25XVN@186806|Eubacteriaceae	186801|Clostridia	V	type I restriction modification DNA specificity domain	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01852	411469.EUBHAL_02708	0.0	1339.0	COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia,25V7M@186806|Eubacteriaceae	186801|Clostridia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
HLKFIFDC_01853	411469.EUBHAL_00869	1.33e-225	620.0	COG0560@1|root,COG0560@2|Bacteria,1TRRS@1239|Firmicutes,249NX@186801|Clostridia,25X3V@186806|Eubacteriaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HAD
HLKFIFDC_01854	411469.EUBHAL_00866	6.38e-193	535.0	COG1606@1|root,COG1606@2|Bacteria,1TPB2@1239|Firmicutes,2485J@186801|Clostridia,25V64@186806|Eubacteriaceae	186801|Clostridia	S	TIGR00268 family	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	ATP_bind_3,NAD_synthase,QueC
HLKFIFDC_01855	411469.EUBHAL_00865	5.03e-95	277.0	COG1661@1|root,COG1661@2|Bacteria,1VBWE@1239|Firmicutes,24HQ2@186801|Clostridia,25XHZ@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K06934	-	-	-	-	ko00000	-	-	-	DUF296
HLKFIFDC_01856	411469.EUBHAL_00864	1.06e-149	421.0	COG0176@1|root,COG0176@2|Bacteria,1TP4Q@1239|Firmicutes,248KZ@186801|Clostridia,25V2P@186806|Eubacteriaceae	186801|Clostridia	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
HLKFIFDC_01857	411469.EUBHAL_00862	1.73e-176	493.0	COG1349@1|root,COG1349@2|Bacteria,1UZ6T@1239|Firmicutes,24B16@186801|Clostridia,25XH8@186806|Eubacteriaceae	186801|Clostridia	K	Transcriptional regulator, DeoR family	-	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
HLKFIFDC_01858	411469.EUBHAL_00860	5.9e-313	854.0	COG2233@1|root,COG2233@2|Bacteria,1TQKX@1239|Firmicutes,2485Z@186801|Clostridia,25VSJ@186806|Eubacteriaceae	186801|Clostridia	F	Psort location CytoplasmicMembrane, score 10.00	uraA	-	-	ko:K02824	-	-	-	-	ko00000,ko02000	2.A.40.1.1,2.A.40.1.2	-	-	Xan_ur_permease
HLKFIFDC_01859	411469.EUBHAL_00859	6.42e-128	363.0	COG0655@1|root,COG0655@2|Bacteria,1TQKC@1239|Firmicutes,24H9P@186801|Clostridia,25WUC@186806|Eubacteriaceae	186801|Clostridia	S	Flavodoxin-like fold	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
HLKFIFDC_01860	411469.EUBHAL_00858	4.38e-102	295.0	COG1671@1|root,COG1671@2|Bacteria,1V9Z0@1239|Firmicutes,24HPW@186801|Clostridia,25WGU@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the UPF0178 family	-	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
HLKFIFDC_01861	697329.Rumal_3660	8.07e-218	607.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia,3WJ00@541000|Ruminococcaceae	186801|Clostridia	L	transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
HLKFIFDC_01863	411469.EUBHAL_00698	4.19e-42	139.0	COG3950@1|root,COG3950@2|Bacteria,1UK6W@1239|Firmicutes,25FNK@186801|Clostridia,25XQN@186806|Eubacteriaceae	186801|Clostridia	L	AAA domain	-	-	-	ko:K07459	-	-	-	-	ko00000	-	-	-	AAA_15
HLKFIFDC_01864	411469.EUBHAL_00697	4.78e-111	320.0	28P26@1|root,2ZBYA@2|Bacteria,1V1VU@1239|Firmicutes,24GBU@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01865	411469.EUBHAL_00696	2.83e-240	660.0	COG4637@1|root,COG4637@2|Bacteria,1V0EX@1239|Firmicutes,24B14@186801|Clostridia,25YTB@186806|Eubacteriaceae	186801|Clostridia	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21,AAA_23
HLKFIFDC_01866	1121115.AXVN01000043_gene3376	0.0	1256.0	COG1061@1|root,COG3886@1|root,COG1061@2|Bacteria,COG3886@2|Bacteria,1TQ62@1239|Firmicutes,249TK@186801|Clostridia	186801|Clostridia	L	helicase	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,PLDc_2,ResIII
HLKFIFDC_01867	1121115.AXVN01000043_gene3375	3.45e-98	290.0	COG2227@1|root,COG2227@2|Bacteria,1V1MT@1239|Firmicutes,24FTN@186801|Clostridia,3Y29B@572511|Blautia	186801|Clostridia	H	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25,NUDIX
HLKFIFDC_01869	1256908.HMPREF0373_02490	3.98e-195	553.0	COG2865@1|root,COG2865@2|Bacteria,1U8FY@1239|Firmicutes,24B8W@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4,HTH_24
HLKFIFDC_01870	1256908.HMPREF0373_02490	6.76e-32	122.0	COG2865@1|root,COG2865@2|Bacteria,1U8FY@1239|Firmicutes,24B8W@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4,HTH_24
HLKFIFDC_01871	411469.EUBHAL_00685	3.49e-48	153.0	2E3HI@1|root,32YG4@2|Bacteria,1VHJH@1239|Firmicutes,24V52@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01872	411469.EUBHAL_00684	3.03e-56	184.0	COG0846@1|root,COG0846@2|Bacteria,1TQB7@1239|Firmicutes,247UN@186801|Clostridia,25VAE@186806|Eubacteriaceae	186801|Clostridia	K	COG COG0846 NAD-dependent protein deacetylases, SIR2 family	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01873	411469.EUBHAL_00683	2.91e-183	509.0	COG2110@1|root,COG2110@2|Bacteria,1TQSZ@1239|Firmicutes,24935@186801|Clostridia,25VSH@186806|Eubacteriaceae	186801|Clostridia	T	Macro domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Macro
HLKFIFDC_01874	1235790.C805_01254	5.22e-90	271.0	COG1802@1|root,COG1802@2|Bacteria,1V6ZD@1239|Firmicutes,24IW5@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
HLKFIFDC_01875	411469.EUBHAL_02754	1.48e-218	603.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,25VAS@186806|Eubacteriaceae	186801|Clostridia	GK	ROK family	glcK	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
HLKFIFDC_01876	411469.EUBHAL_02753	3.83e-257	704.0	COG0502@1|root,COG0502@2|Bacteria,1TPYQ@1239|Firmicutes,248H8@186801|Clostridia,25UZ7@186806|Eubacteriaceae	186801|Clostridia	C	Iron-only hydrogenase maturation rSAM protein HydE	hydE	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
HLKFIFDC_01877	411469.EUBHAL_02752	2.06e-38	128.0	COG1983@1|root,COG1983@2|Bacteria,1VKBQ@1239|Firmicutes,24QU9@186801|Clostridia,25XUP@186806|Eubacteriaceae	186801|Clostridia	KT	PspC domain	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
HLKFIFDC_01878	411469.EUBHAL_02751	0.0	1008.0	COG1686@1|root,COG1686@2|Bacteria,1V50I@1239|Firmicutes,24I5G@186801|Clostridia,25YWM@186806|Eubacteriaceae	186801|Clostridia	M	Beta-lactamase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S11
HLKFIFDC_01879	411469.EUBHAL_02750	1.11e-198	549.0	COG0770@1|root,COG0770@2|Bacteria,1V1NG@1239|Firmicutes,24GE1@186801|Clostridia,25XC0@186806|Eubacteriaceae	186801|Clostridia	M	Zinc dependent phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
HLKFIFDC_01880	411469.EUBHAL_02749	7.86e-304	828.0	COG4198@1|root,COG4198@2|Bacteria,1TQ52@1239|Firmicutes,24985@186801|Clostridia,25VHP@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
HLKFIFDC_01881	411469.EUBHAL_02748	0.0	1151.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247Q9@186801|Clostridia,25V5B@186806|Eubacteriaceae	186801|Clostridia	S	of ABC transporters with duplicated ATPase	yfmR	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
HLKFIFDC_01883	411469.EUBHAL_02745	0.0	2482.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1TPAS@1239|Firmicutes,247W2@186801|Clostridia,25V77@186806|Eubacteriaceae	186801|Clostridia	F	Psort location Cytoplasmic, score	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
HLKFIFDC_01884	411469.EUBHAL_02744	3.15e-229	630.0	COG3608@1|root,COG3608@2|Bacteria,1UXZC@1239|Firmicutes,24BEB@186801|Clostridia,25W4G@186806|Eubacteriaceae	186801|Clostridia	S	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
HLKFIFDC_01885	411469.EUBHAL_02743	1.76e-232	639.0	COG3608@1|root,COG3608@2|Bacteria,1TSBT@1239|Firmicutes,24A92@186801|Clostridia,25W37@186806|Eubacteriaceae	186801|Clostridia	S	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
HLKFIFDC_01886	411469.EUBHAL_02742	7.13e-115	328.0	COG1854@1|root,COG1854@2|Bacteria,1V1CH@1239|Firmicutes,24G3R@186801|Clostridia,25WAK@186806|Eubacteriaceae	186801|Clostridia	H	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)	luxS	-	4.4.1.21	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	M00609	R01291	RC00069,RC01929	ko00000,ko00001,ko00002,ko01000	-	-	-	LuxS
HLKFIFDC_01887	411469.EUBHAL_02741	3.94e-41	135.0	2C4UR@1|root,33E7U@2|Bacteria,1W1BJ@1239|Firmicutes,24V2B@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01889	411469.EUBHAL_02737	6.34e-183	509.0	COG2768@1|root,COG2768@2|Bacteria,1V2K1@1239|Firmicutes,24FX2@186801|Clostridia,25VW2@186806|Eubacteriaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4,Flavodoxin_5
HLKFIFDC_01892	411469.EUBHAL_02734	5.11e-243	669.0	COG1705@1|root,COG1705@2|Bacteria,1V7JY@1239|Firmicutes,24C0T@186801|Clostridia,25ZAN@186806|Eubacteriaceae	186801|Clostridia	NU	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,Amidase_3,CW_7,CW_binding_1,Cu_amine_oxidN1,Glucosaminidase,PG_binding_1
HLKFIFDC_01893	411469.EUBHAL_02733	8.04e-72	216.0	COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,24JBJ@186801|Clostridia,25WAZ@186806|Eubacteriaceae	186801|Clostridia	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
HLKFIFDC_01894	411469.EUBHAL_02732	1.19e-33	116.0	COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,24QJD@186801|Clostridia,25X8W@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
HLKFIFDC_01895	411469.EUBHAL_02731	4.22e-105	304.0	COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes,24FUS@186801|Clostridia,25WSI@186806|Eubacteriaceae	186801|Clostridia	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
HLKFIFDC_01896	411469.EUBHAL_02730	7.41e-117	333.0	COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,24HF0@186801|Clostridia,25W7R@186806|Eubacteriaceae	186801|Clostridia	F	Psort location Cytoplasmic, score	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
HLKFIFDC_01897	411469.EUBHAL_02729	8.1e-281	768.0	COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,24811@186801|Clostridia,25V9Z@186806|Eubacteriaceae	186801|Clostridia	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
HLKFIFDC_01898	411469.EUBHAL_02728	1.72e-286	783.0	COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,248MU@186801|Clostridia,25VIR@186806|Eubacteriaceae	186801|Clostridia	E	homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
HLKFIFDC_01899	411469.EUBHAL_02727	6.75e-96	280.0	COG4492@1|root,COG4492@2|Bacteria,1VAJ9@1239|Firmicutes,24MTS@186801|Clostridia,25X4F@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the UPF0735 family	pheB	-	5.4.99.5	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_4
HLKFIFDC_01900	411469.EUBHAL_02725	4.12e-128	364.0	COG0317@1|root,COG0317@2|Bacteria,1VAH0@1239|Firmicutes,24MVX@186801|Clostridia,25X2U@186806|Eubacteriaceae	186801|Clostridia	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_4
HLKFIFDC_01901	411469.EUBHAL_02724	0.0	1354.0	COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia,25V6M@186806|Eubacteriaceae	186801|Clostridia	J	Psort location Cytoplasmic, score	fusA2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
HLKFIFDC_01902	411469.EUBHAL_02723	1.53e-265	727.0	COG0287@1|root,COG0287@2|Bacteria,1TPXG@1239|Firmicutes,248KX@186801|Clostridia,25V6J@186806|Eubacteriaceae	186801|Clostridia	E	prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDH
HLKFIFDC_01903	411469.EUBHAL_03103	1.94e-305	833.0	COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,2488G@186801|Clostridia,25VR8@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
HLKFIFDC_01904	411469.EUBHAL_03102	2.16e-265	729.0	COG5434@1|root,COG5434@2|Bacteria,1UK75@1239|Firmicutes,25FNX@186801|Clostridia	186801|Clostridia	M	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01905	411469.EUBHAL_01467	0.0	2637.0	COG5492@1|root,COG5492@2|Bacteria,1V32P@1239|Firmicutes,25FDC@186801|Clostridia,25ZTW@186806|Eubacteriaceae	186801|Clostridia	N	Psort location Cellwall, score	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
HLKFIFDC_01906	411469.EUBHAL_00757	1.24e-154	439.0	COG5464@1|root,COG5464@2|Bacteria,1V263@1239|Firmicutes,25FNN@186801|Clostridia,25ZUE@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
HLKFIFDC_01909	411469.EUBHAL_00753	6.71e-93	271.0	COG0242@1|root,COG0242@2|Bacteria,1V73T@1239|Firmicutes,24FT0@186801|Clostridia,25WFJ@186806|Eubacteriaceae	186801|Clostridia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins	def2	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
HLKFIFDC_01910	411469.EUBHAL_00752	0.0	1679.0	COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,248M3@186801|Clostridia,25V3M@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
HLKFIFDC_01912	411469.EUBHAL_00750	6.87e-170	477.0	COG1606@1|root,COG1606@2|Bacteria,1TPB2@1239|Firmicutes,2485J@186801|Clostridia,25V64@186806|Eubacteriaceae	186801|Clostridia	S	TIGR00268 family	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	ATP_bind_3,NAD_synthase,QueC
HLKFIFDC_01913	411469.EUBHAL_00749	3.8e-76	227.0	COG0139@1|root,COG0139@2|Bacteria,1UYNA@1239|Firmicutes,247RS@186801|Clostridia,25VEX@186806|Eubacteriaceae	186801|Clostridia	E	Belongs to the	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS05760	His_biosynth,PRA-CH,PRA-PH
HLKFIFDC_01914	411469.EUBHAL_00748	6.01e-141	397.0	COG0131@1|root,COG0131@2|Bacteria,1TRH7@1239|Firmicutes,247WC@186801|Clostridia,25VZA@186806|Eubacteriaceae	186801|Clostridia	E	imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
HLKFIFDC_01915	411469.EUBHAL_00747	2.63e-294	806.0	COG0141@1|root,COG0141@2|Bacteria,1TPAW@1239|Firmicutes,248X8@186801|Clostridia,25UT7@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
HLKFIFDC_01916	411469.EUBHAL_00746	7.17e-146	411.0	COG0040@1|root,COG0040@2|Bacteria,1TSVZ@1239|Firmicutes,249AR@186801|Clostridia,25VPN@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
HLKFIFDC_01917	411469.EUBHAL_00745	5.49e-300	818.0	COG3705@1|root,COG3705@2|Bacteria,1TPZZ@1239|Firmicutes,248CB@186801|Clostridia,25VEV@186806|Eubacteriaceae	186801|Clostridia	E	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
HLKFIFDC_01918	411469.EUBHAL_02670	2.28e-89	264.0	COG3428@1|root,COG3428@2|Bacteria,1V9YB@1239|Firmicutes,24MQT@186801|Clostridia,25XEW@186806|Eubacteriaceae	186801|Clostridia	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
HLKFIFDC_01919	411469.EUBHAL_02669	0.0	1134.0	COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,248RK@186801|Clostridia,25V20@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	FbpA	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
HLKFIFDC_01920	411469.EUBHAL_02667	0.0	965.0	COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,248G1@186801|Clostridia,25UT1@186806|Eubacteriaceae	186801|Clostridia	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
HLKFIFDC_01921	411469.EUBHAL_02663	2e-160	452.0	COG2145@1|root,COG2145@2|Bacteria,1V1R6@1239|Firmicutes,248AC@186801|Clostridia,25VP7@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)	thiM	-	2.7.1.50	ko:K00878	ko00730,ko01100,map00730,map01100	M00127	R04448	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HK
HLKFIFDC_01922	411469.EUBHAL_02664	4.39e-110	321.0	COG0352@1|root,COG0352@2|Bacteria,1V3ZR@1239|Firmicutes,24DG3@186801|Clostridia,25VF2@186806|Eubacteriaceae	186801|Clostridia	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
HLKFIFDC_01923	411469.EUBHAL_02665	0.0	943.0	COG0351@1|root,COG0637@1|root,COG0351@2|Bacteria,COG0637@2|Bacteria,1TQ4A@1239|Firmicutes,2483H@186801|Clostridia,25VDZ@186806|Eubacteriaceae	186801|Clostridia	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
HLKFIFDC_01924	411469.EUBHAL_02666	0.0	876.0	COG0422@1|root,COG0422@2|Bacteria,1TNZ3@1239|Firmicutes,247JE@186801|Clostridia,25V8T@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC_Rad_SAM
HLKFIFDC_01925	471875.RUMLAC_02264	9.57e-96	294.0	COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,249B3@186801|Clostridia,3WHE1@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	dacF	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
HLKFIFDC_01926	411469.EUBHAL_00948	4.89e-203	562.0	COG1307@1|root,COG1307@2|Bacteria,1TSKD@1239|Firmicutes,24AE9@186801|Clostridia,25W8S@186806|Eubacteriaceae	186801|Clostridia	S	Uncharacterised protein, DegV family COG1307	-	-	-	-	-	-	-	-	-	-	-	-	DegV
HLKFIFDC_01927	411469.EUBHAL_00949	2.62e-108	312.0	COG0789@1|root,COG0789@2|Bacteria,1V7Z4@1239|Firmicutes,24IDK@186801|Clostridia	186801|Clostridia	K	Domain of unknown function (DUF1836)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1836
HLKFIFDC_01928	411469.EUBHAL_00950	3.56e-189	525.0	COG1342@1|root,COG1433@1|root,COG1342@2|Bacteria,COG1433@2|Bacteria,1TRMQ@1239|Firmicutes,25E8C@186801|Clostridia,25W3Q@186806|Eubacteriaceae	186801|Clostridia	S	Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	DUF134,Nitro_FeMo-Co
HLKFIFDC_01929	411469.EUBHAL_00951	2.15e-104	301.0	COG1846@1|root,COG1846@2|Bacteria,1V3G1@1239|Firmicutes,24G8T@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
HLKFIFDC_01930	411469.EUBHAL_00952	4.48e-160	448.0	2DB6M@1|root,2Z7HS@2|Bacteria,1U8V8@1239|Firmicutes,249IN@186801|Clostridia,25X1G@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2871
HLKFIFDC_01932	411469.EUBHAL_00954	0.0	1034.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,25VGV@186806|Eubacteriaceae	186801|Clostridia	L	Domain of unknown function (DUF4368)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
HLKFIFDC_01933	411469.EUBHAL_00955	7.46e-121	348.0	COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,249B3@186801|Clostridia,25V0A@186806|Eubacteriaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	dacF	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
HLKFIFDC_01934	411469.EUBHAL_00956	0.0	1341.0	COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,247WH@186801|Clostridia,25UX0@186806|Eubacteriaceae	186801|Clostridia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
HLKFIFDC_01935	411469.EUBHAL_00957	1.31e-162	456.0	COG1354@1|root,COG1354@2|Bacteria,1TRW3@1239|Firmicutes,249VW@186801|Clostridia,25VKF@186806|Eubacteriaceae	186801|Clostridia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
HLKFIFDC_01936	411469.EUBHAL_00958	6.44e-127	362.0	COG1386@1|root,COG1386@2|Bacteria,1V6HI@1239|Firmicutes,24JW7@186801|Clostridia,25WUM@186806|Eubacteriaceae	186801|Clostridia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
HLKFIFDC_01937	411469.EUBHAL_00959	5.37e-312	852.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,25UUM@186806|Eubacteriaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HLKFIFDC_01938	1121115.AXVN01000069_gene2308	6.7e-09	55.8	COG0737@1|root,COG1653@1|root,COG0737@2|Bacteria,COG1653@2|Bacteria,1V2W6@1239|Firmicutes,249GG@186801|Clostridia	186801|Clostridia	FG	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	5_nucleotid_C,SBP_bac_8,TAT_signal
HLKFIFDC_01939	1121115.AXVN01000069_gene2309	2.5e-16	79.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,3XZ5S@572511|Blautia	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg
HLKFIFDC_01940	742765.HMPREF9457_03028	4.79e-16	77.4	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,27W33@189330|Dorea	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
HLKFIFDC_01941	411459.RUMOBE_03989	9.65e-182	507.0	COG0834@1|root,COG0834@2|Bacteria,1UYKY@1239|Firmicutes,24C0B@186801|Clostridia,3Y14K@572511|Blautia	186801|Clostridia	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
HLKFIFDC_01942	1256908.HMPREF0373_00503	0.0	1243.0	COG0642@1|root,COG0784@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria,1TSDF@1239|Firmicutes,250SJ@186801|Clostridia,25ZJN@186806|Eubacteriaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
HLKFIFDC_01943	411469.EUBHAL_00966	0.0	1218.0	COG0737@1|root,COG1653@1|root,COG0737@2|Bacteria,COG1653@2|Bacteria,1U6YH@1239|Firmicutes,24ENB@186801|Clostridia,25X3S@186806|Eubacteriaceae	186801|Clostridia	P	Bacterial extracellular solute-binding protein	-	-	3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SBP_bac_1,SBP_bac_8
HLKFIFDC_01944	411469.EUBHAL_00967	0.0	1815.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,25V53@186806|Eubacteriaceae	186801|Clostridia	T	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg,SBP_bac_3,dCache_1
HLKFIFDC_01945	411469.EUBHAL_00968	0.0	1550.0	COG0642@1|root,COG0834@1|root,COG0642@2|Bacteria,COG0834@2|Bacteria,1UYZX@1239|Firmicutes,25E9T@186801|Clostridia,25ZJZ@186806|Eubacteriaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C,HATPase_c,HisKA,Response_reg,SBP_bac_3,dCache_1
HLKFIFDC_01946	411469.EUBHAL_00969	4.07e-172	481.0	COG0428@1|root,COG0428@2|Bacteria,1TP7J@1239|Firmicutes,247Q2@186801|Clostridia,25V37@186806|Eubacteriaceae	186801|Clostridia	P	Metal cation transporter, ZIP family	zupT	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
HLKFIFDC_01947	457412.RSAG_02488	1.72e-15	74.7	COG1609@1|root,COG1609@2|Bacteria,1UM0E@1239|Firmicutes,25B2H@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
HLKFIFDC_01948	742765.HMPREF9457_02049	0.0	1919.0	COG4932@1|root,COG4932@2|Bacteria,1TS9Q@1239|Firmicutes,24AX1@186801|Clostridia	186801|Clostridia	M	Psort location Cellwall, score	-	-	-	-	-	-	-	-	-	-	-	-	Gram_pos_anchor
HLKFIFDC_01949	1504823.CCMM01000013_gene2508	1.57e-71	215.0	2BXTH@1|root,2ZZ52@2|Bacteria	2|Bacteria	S	COG NOG10998 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF961
HLKFIFDC_01950	742765.HMPREF9457_02046	6.14e-87	255.0	28NIV@1|root,2ZBK5@2|Bacteria,1V1U5@1239|Firmicutes,24FW5@186801|Clostridia,27WXP@189330|Dorea	186801|Clostridia	S	Bacterial protein of unknown function (DUF961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF961
HLKFIFDC_01951	585501.HMPREF6123_2233	5.23e-21	92.4	2BETB@1|root,328IX@2|Bacteria,1UUGM@1239|Firmicutes,256QI@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01952	742723.HMPREF9477_00865	0.0	927.0	COG1674@1|root,COG1674@2|Bacteria,1TPHE@1239|Firmicutes,249WR@186801|Clostridia,27K03@186928|unclassified Lachnospiraceae	186801|Clostridia	D	COG COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF87,FtsK_SpoIIIE
HLKFIFDC_01953	658659.HMPREF0983_00908	6.29e-292	796.0	COG2946@1|root,COG2946@2|Bacteria,1UHNT@1239|Firmicutes,3VP4X@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Replication initiation factor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Rep_trans
HLKFIFDC_01954	658659.HMPREF0983_00907	4.47e-18	75.5	2E3NJ@1|root,32YKN@2|Bacteria,1VIHR@1239|Firmicutes,3VRKR@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Protein of unknown function (DUF3789)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3789
HLKFIFDC_01955	411470.RUMGNA_02421	5.89e-42	137.0	2C9BX@1|root,32RP2@2|Bacteria,1VANR@1239|Firmicutes,24N4I@186801|Clostridia,3Y1X2@572511|Blautia	186801|Clostridia	S	COG NOG13238 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01957	411470.RUMGNA_02424	1.31e-63	194.0	2AJ8P@1|root,319TK@2|Bacteria,1V9F5@1239|Firmicutes,24KKK@186801|Clostridia,3Y1MX@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01958	742765.HMPREF9457_02578	3.66e-113	324.0	COG4734@1|root,COG4734@2|Bacteria,1UX6H@1239|Firmicutes,24AM6@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	ArdA
HLKFIFDC_01959	1235790.C805_01415	6.25e-122	347.0	COG4734@1|root,COG4734@2|Bacteria,1TNY7@1239|Firmicutes,249HA@186801|Clostridia,25WNI@186806|Eubacteriaceae	186801|Clostridia	S	Antirestriction protein (ArdA)	-	-	-	-	-	-	-	-	-	-	-	-	ArdA
HLKFIFDC_01960	665950.HMPREF1025_00443	2.03e-92	270.0	28I70@1|root,2Z89W@2|Bacteria,1V1TC@1239|Firmicutes,24FQV@186801|Clostridia,27NBR@186928|unclassified Lachnospiraceae	186801|Clostridia	S	TcpE family	-	-	-	-	-	-	-	-	-	-	-	-	TcpE
HLKFIFDC_01961	1235790.C805_01413	0.0	1550.0	COG0433@1|root,COG0433@2|Bacteria,1TPVQ@1239|Firmicutes,24AAP@186801|Clostridia,25VYU@186806|Eubacteriaceae	186801|Clostridia	S	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10
HLKFIFDC_01962	469596.HMPREF9488_00503	0.0	1264.0	COG3064@1|root,COG3064@2|Bacteria,1UIYZ@1239|Firmicutes,3VQ0R@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01963	445973.CLOBAR_01099	2.08e-240	660.0	COG0741@1|root,COG0791@1|root,COG0741@2|Bacteria,COG0791@2|Bacteria,1TP24@1239|Firmicutes,247K5@186801|Clostridia,25QMU@186804|Peptostreptococcaceae	186801|Clostridia	M	Lysozyme-like	-	-	-	-	-	-	-	-	-	-	-	-	Lysozyme_like,NLPC_P60
HLKFIFDC_01964	665950.HMPREF1025_00447	1.15e-205	570.0	28IGH@1|root,2Z8HY@2|Bacteria,1TQX2@1239|Firmicutes,249TA@186801|Clostridia,27KG9@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Conjugative transposon protein TcpC	-	-	-	-	-	-	-	-	-	-	-	-	TpcC
HLKFIFDC_01965	500632.CLONEX_02863	1.32e-43	142.0	COG1476@1|root,COG1476@2|Bacteria,1VEGF@1239|Firmicutes,24QPB@186801|Clostridia	186801|Clostridia	K	DNA-binding helix-turn-helix protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HLKFIFDC_01966	500632.CLONEX_02864	3.22e-65	199.0	2E12F@1|root,32WI5@2|Bacteria,1VD2P@1239|Firmicutes,24PDX@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01967	500632.CLONEX_02865	1.25e-67	205.0	2EPDA@1|root,33GZW@2|Bacteria,1W3CC@1239|Firmicutes,256NJ@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01968	1256908.HMPREF0373_00069	1.3e-39	132.0	COG0582@1|root,COG0582@2|Bacteria,1VBGF@1239|Firmicutes,24NRM@186801|Clostridia,25YTQ@186806|Eubacteriaceae	186801|Clostridia	L	viral genome integration into host DNA	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01969	1280685.AUKC01000002_gene2791	1.42e-90	274.0	COG1131@1|root,COG1131@2|Bacteria,1TP4J@1239|Firmicutes,253U3@186801|Clostridia,4BY2W@830|Butyrivibrio	186801|Clostridia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	M00254,M00817	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.124.1,3.A.1.124.2,3.A.1.124.6	-	-	ABC_tran
HLKFIFDC_01970	1501230.ET33_17760	2.29e-21	97.1	COG4200@1|root,COG4200@2|Bacteria,1TRRE@1239|Firmicutes,4HG0V@91061|Bacilli,26TY1@186822|Paenibacillaceae	91061|Bacilli	S	ABC-2 family transporter protein	-	-	-	ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	M00817	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.124.1,3.A.1.124.2,3.A.1.124.6	-	-	ABC2_membrane_4
HLKFIFDC_01972	873447.SPB_1070	2.91e-75	233.0	COG0745@1|root,COG0745@2|Bacteria,1TQ0D@1239|Firmicutes	1239|Firmicutes	KT	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	spaR	-	-	ko:K20488	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HLKFIFDC_01973	1235798.C817_02688	1.15e-29	128.0	COG0642@1|root,COG2205@2|Bacteria,1TS1G@1239|Firmicutes,248TF@186801|Clostridia,27W66@189330|Dorea	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K20487	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
HLKFIFDC_01974	1280698.AUJS01000076_gene3400	1.18e-78	234.0	COG1396@1|root,COG1396@2|Bacteria,1V4ZE@1239|Firmicutes,24J34@186801|Clostridia,27X28@189330|Dorea	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
HLKFIFDC_01975	908340.HMPREF9406_0786	4.31e-86	254.0	COG1191@1|root,COG1191@2|Bacteria,1UJ7B@1239|Firmicutes,24KND@186801|Clostridia,36V54@31979|Clostridiaceae	186801|Clostridia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4,Sigma70_r4_2
HLKFIFDC_01976	908340.HMPREF9406_0785	1.99e-44	144.0	2AJW5@1|root,31AIZ@2|Bacteria,1V7QN@1239|Firmicutes,24JQH@186801|Clostridia,36PDP@31979|Clostridiaceae	186801|Clostridia	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_16
HLKFIFDC_01977	500632.CLONEX_03693	1.4e-36	123.0	2EQGP@1|root,33I2P@2|Bacteria,1VKY1@1239|Firmicutes,24SQ3@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01978	500632.CLONEX_03692	1.95e-293	801.0	COG0582@1|root,COG0582@2|Bacteria,1VRCP@1239|Firmicutes,24BDU@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_DNA,Phage_int_SAM_3,Phage_integrase
HLKFIFDC_01979	411469.EUBHAL_00971	0.0	1558.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,25VNK@186806|Eubacteriaceae	186801|Clostridia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
HLKFIFDC_01980	1304880.JAGB01000002_gene2395	1.95e-17	84.0	COG0745@1|root,COG0745@2|Bacteria,1TPF7@1239|Firmicutes,24916@186801|Clostridia	186801|Clostridia	KT	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process	spo0A	-	-	ko:K07699	ko02020,ko02024,map02020,map02024	M00485	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Spo0A_C
HLKFIFDC_01981	411469.EUBHAL_03100	1.9e-173	483.0	29XBC@1|root,30J12@2|Bacteria,1UGNA@1239|Firmicutes,24WPR@186801|Clostridia,25Z9G@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
HLKFIFDC_01983	411469.EUBHAL_00946	1.11e-307	839.0	COG0038@1|root,COG0038@2|Bacteria,1TPX0@1239|Firmicutes,247R4@186801|Clostridia,25VA0@186806|Eubacteriaceae	186801|Clostridia	P	Chloride transporter, ClC family	clcA	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	TrkA_C,Voltage_CLC
HLKFIFDC_01984	411469.EUBHAL_00944	0.0	1125.0	COG0119@1|root,COG0119@2|Bacteria,1TP4Y@1239|Firmicutes,2485A@186801|Clostridia,25VMR@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13,2.3.3.14	ko:K01649,ko:K02594	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R00271,R01213	RC00004,RC00067,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,HTH_18,LeuA_dimer
HLKFIFDC_01985	411469.EUBHAL_00941	0.0	887.0	COG2199@1|root,COG4684@1|root,COG2199@2|Bacteria,COG4684@2|Bacteria,1UK6Z@1239|Firmicutes,25FNP@186801|Clostridia,25WH7@186806|Eubacteriaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
HLKFIFDC_01987	411469.EUBHAL_00506	0.0	1734.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,25VEG@186806|Eubacteriaceae	186801|Clostridia	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
HLKFIFDC_01988	411470.RUMGNA_02292	2.5e-83	256.0	COG1192@1|root,COG1192@2|Bacteria,1VGAI@1239|Firmicutes,24U38@186801|Clostridia	186801|Clostridia	D	4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
HLKFIFDC_01989	411469.EUBHAL_02340	5.67e-266	731.0	COG1475@1|root,COG1475@2|Bacteria,1V5GZ@1239|Firmicutes,24HAS@186801|Clostridia,25Z6Z@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	ParBc
HLKFIFDC_01990	411469.EUBHAL_00604	2.3e-99	295.0	2DBC6@1|root,2Z8BZ@2|Bacteria,1TQXM@1239|Firmicutes,2484N@186801|Clostridia,25W7W@186806|Eubacteriaceae	186801|Clostridia	S	Replication initiator protein A (RepA) N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	RepA_N
HLKFIFDC_01991	411469.EUBHAL_00606	8.61e-167	467.0	COG4509@1|root,COG4509@2|Bacteria,1TRWN@1239|Firmicutes,24JWH@186801|Clostridia,25ZG9@186806|Eubacteriaceae	186801|Clostridia	S	Sortase family	srtB	-	3.4.22.70	ko:K08600	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
HLKFIFDC_01992	411469.EUBHAL_00608	1.34e-37	131.0	COG3682@1|root,COG3682@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
HLKFIFDC_01993	1392491.JIAE01000001_gene88	5.62e-23	98.2	COG1396@1|root,COG1396@2|Bacteria,1V1JY@1239|Firmicutes,24R5G@186801|Clostridia,3WRJ3@541000|Ruminococcaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HLKFIFDC_01994	411469.EUBHAL_01178	1.66e-91	272.0	2DWIZ@1|root,340JX@2|Bacteria,1VXCR@1239|Firmicutes,2524A@186801|Clostridia	411469.EUBHAL_01178|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01996	742740.HMPREF9474_02076	1e-78	235.0	2BJYY@1|root,32EBR@2|Bacteria,1V8QR@1239|Firmicutes,24M1F@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01997	658086.HMPREF0994_05190	3.45e-128	367.0	291XE@1|root,2ZPH0@2|Bacteria,1V4WP@1239|Firmicutes,24I5M@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_01998	1042156.CXIVA_12710	1.39e-32	121.0	COG1476@1|root,COG1476@2|Bacteria,1TP7T@1239|Firmicutes,24G95@186801|Clostridia,36IIC@31979|Clostridiaceae	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	ko:K07726	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
HLKFIFDC_01999	500632.CLONEX_00012	7.98e-53	180.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia	186801|Clostridia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	tRNA_U5-meth_tr
HLKFIFDC_02000	1256908.HMPREF0373_02451	7.98e-63	193.0	2C5R4@1|root,2ZRGD@2|Bacteria,1V4WH@1239|Firmicutes,24HA6@186801|Clostridia,25WJJ@186806|Eubacteriaceae	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
HLKFIFDC_02001	742765.HMPREF9457_02003	3.93e-150	423.0	COG0745@1|root,COG0745@2|Bacteria,1TSNV@1239|Firmicutes,2493A@186801|Clostridia,27WSY@189330|Dorea	186801|Clostridia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HLKFIFDC_02002	411469.EUBHAL_02127	1.21e-194	542.0	COG0642@1|root,COG2205@2|Bacteria,1TR7T@1239|Firmicutes,24CJ8@186801|Clostridia,25W55@186806|Eubacteriaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
HLKFIFDC_02003	411463.EUBVEN_00936	1.81e-150	424.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,25V30@186806|Eubacteriaceae	186801|Clostridia	V	ABC transporter, ATP-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HLKFIFDC_02004	411463.EUBVEN_00935	0.0	1453.0	COG0577@1|root,COG0577@2|Bacteria,1TRAS@1239|Firmicutes,248SQ@186801|Clostridia,25UYY@186806|Eubacteriaceae	186801|Clostridia	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
HLKFIFDC_02005	500632.CLONEX_01380	3.41e-104	317.0	COG2433@1|root,COG2433@2|Bacteria,1UI5D@1239|Firmicutes,25EHI@186801|Clostridia	186801|Clostridia	S	MobA MobL family protein	-	-	-	-	-	-	-	-	-	-	-	-	MobA_MobL
HLKFIFDC_02006	411469.EUBHAL_01178	9.66e-19	83.6	2DWIZ@1|root,340JX@2|Bacteria,1VXCR@1239|Firmicutes,2524A@186801|Clostridia	411469.EUBHAL_01178|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02008	478749.BRYFOR_07025	1.19e-229	647.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,248FH@186801|Clostridia	186801|Clostridia	L	ImpB MucB SamB family protein	-	-	-	ko:K03502	-	-	-	-	ko00000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
HLKFIFDC_02009	411469.EUBHAL_01567	1e-96	281.0	2DMPJ@1|root,32SWG@2|Bacteria,1V7RA@1239|Firmicutes,24NGU@186801|Clostridia,25XF2@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02011	411469.EUBHAL_00736	8.35e-13	65.1	COG1813@1|root,COG1813@2|Bacteria,1UK6X@1239|Firmicutes,25FNM@186801|Clostridia,25XWR@186806|Eubacteriaceae	2|Bacteria	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_26,HTH_3
HLKFIFDC_02012	1256908.HMPREF0373_02036	0.0	1743.0	COG0642@1|root,COG0784@1|root,COG0834@1|root,COG0784@2|Bacteria,COG0834@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,25VMM@186806|Eubacteriaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg,SBP_bac_3
HLKFIFDC_02014	411461.DORFOR_03058	1.51e-38	132.0	2F9PY@1|root,34204@2|Bacteria,1VY8B@1239|Firmicutes,252B3@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02015	518637.EUBIFOR_02186	2.63e-192	578.0	COG0642@1|root,COG0784@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,1V0S7@1239|Firmicutes,3VQ3Q@526524|Erysipelotrichia	526524|Erysipelotrichia	T	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_9,Response_reg
HLKFIFDC_02016	411461.DORFOR_03057	4.51e-51	181.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,27W78@189330|Dorea	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_9,Response_reg
HLKFIFDC_02017	411469.EUBHAL_01639	4.25e-120	343.0	COG0716@1|root,COG0716@2|Bacteria,1V465@1239|Firmicutes,24DQZ@186801|Clostridia,25W9A@186806|Eubacteriaceae	186801|Clostridia	C	Flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_4
HLKFIFDC_02018	411469.EUBHAL_01640	8.69e-128	363.0	COG0110@1|root,COG0110@2|Bacteria,1UXZQ@1239|Firmicutes,24J2N@186801|Clostridia,25XZ3@186806|Eubacteriaceae	186801|Clostridia	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
HLKFIFDC_02019	411469.EUBHAL_01641	1.54e-26	103.0	COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,248FK@186801|Clostridia,25VWT@186806|Eubacteriaceae	186801|Clostridia	S	Oxidoreductase, aldo keto reductase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red,MerR_1
HLKFIFDC_02020	411469.EUBHAL_01641	9.25e-119	343.0	COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,248FK@186801|Clostridia,25VWT@186806|Eubacteriaceae	186801|Clostridia	S	Oxidoreductase, aldo keto reductase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red,MerR_1
HLKFIFDC_02021	411459.RUMOBE_03454	4.92e-243	666.0	COG3049@1|root,COG3049@2|Bacteria,1TPZS@1239|Firmicutes,24B0E@186801|Clostridia,3Y087@572511|Blautia	186801|Clostridia	M	COG COG3049 Penicillin V acylase and related amidases	cbh	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	CBAH
HLKFIFDC_02022	411469.EUBHAL_01643	5.46e-161	451.0	COG2357@1|root,COG2357@2|Bacteria,1TQ2F@1239|Firmicutes,249FE@186801|Clostridia,25WDM@186806|Eubacteriaceae	186801|Clostridia	T	Psort location Cytoplasmic, score	-	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
HLKFIFDC_02023	585394.RHOM_13755	0.0	1056.0	COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,247UR@186801|Clostridia	186801|Clostridia	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
HLKFIFDC_02024	411463.EUBVEN_02551	0.0	875.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,24865@186801|Clostridia,25VD8@186806|Eubacteriaceae	186801|Clostridia	C	citrate synthase	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
HLKFIFDC_02025	515620.EUBELI_20658	1.69e-93	273.0	28N68@1|root,2ZBB7@2|Bacteria,1UZ5P@1239|Firmicutes,24EZI@186801|Clostridia,25Y5Y@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02026	411462.DORLON_01574	0.0	958.0	COG1502@1|root,COG1502@2|Bacteria,1TSN8@1239|Firmicutes,249G7@186801|Clostridia,27WIC@189330|Dorea	186801|Clostridia	I	COG COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes	-	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
HLKFIFDC_02027	511680.BUTYVIB_02272	5.44e-155	435.0	COG0745@1|root,COG0745@2|Bacteria,1TSWT@1239|Firmicutes,248B6@186801|Clostridia,4C156@830|Butyrivibrio	186801|Clostridia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HLKFIFDC_02028	411469.EUBHAL_01647	1.42e-244	672.0	COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,249HQ@186801|Clostridia,25VS1@186806|Eubacteriaceae	186801|Clostridia	T	CytoplasmicMembrane, score 9.49	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
HLKFIFDC_02029	411469.EUBHAL_01648	6.59e-245	674.0	2C2TA@1|root,2Z7T7@2|Bacteria,1TS53@1239|Firmicutes,248BA@186801|Clostridia,25W0J@186806|Eubacteriaceae	186801|Clostridia	S	CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	FUSC_2
HLKFIFDC_02030	411461.DORFOR_03005	7.32e-130	369.0	COG0558@1|root,COG0558@2|Bacteria,1V4YR@1239|Firmicutes,24FWZ@186801|Clostridia,27W1S@189330|Dorea	186801|Clostridia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.41	ko:K08744	ko00564,ko01100,map00564,map01100	-	R02030	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
HLKFIFDC_02031	411469.EUBHAL_01651	4.2e-190	529.0	COG3666@1|root,COG3666@2|Bacteria,1TQQ9@1239|Firmicutes,24AG9@186801|Clostridia,25VG2@186806|Eubacteriaceae	186801|Clostridia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
HLKFIFDC_02032	411469.EUBHAL_01652	3.55e-62	197.0	29V65@1|root,338VF@2|Bacteria,1VJN2@1239|Firmicutes,24TEP@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02033	411469.EUBHAL_01653	0.0	869.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,25VAA@186806|Eubacteriaceae	186801|Clostridia	V	CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HLKFIFDC_02034	411469.EUBHAL_01654	4.01e-197	546.0	28JZH@1|root,2Z9PI@2|Bacteria,1V0QF@1239|Firmicutes,248FG@186801|Clostridia,25WID@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4866
HLKFIFDC_02035	411469.EUBHAL_01655	3.95e-170	477.0	COG2966@1|root,COG2966@2|Bacteria,1TNZH@1239|Firmicutes,24BQZ@186801|Clostridia,25VJ6@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ThrE,ThrE_2
HLKFIFDC_02036	411459.RUMOBE_03130	1.31e-82	256.0	COG2966@1|root,COG3610@1|root,COG2966@2|Bacteria,COG3610@2|Bacteria,1TNZH@1239|Firmicutes,24BQZ@186801|Clostridia,3Y170@572511|Blautia	186801|Clostridia	S	Putative threonine/serine exporter	-	-	-	-	-	-	-	-	-	-	-	-	ThrE,ThrE_2
HLKFIFDC_02037	411469.EUBHAL_01659	3.16e-60	185.0	COG5001@1|root,COG5001@2|Bacteria	2|Bacteria	T	cyclic-guanylate-specific phosphodiesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,Response_reg,dCache_1
HLKFIFDC_02040	411469.EUBHAL_00380	0.0	1176.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,247Z3@186801|Clostridia,25V6K@186806|Eubacteriaceae	186801|Clostridia	J	L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
HLKFIFDC_02041	411469.EUBHAL_00379	1.16e-139	394.0	COG3437@1|root,COG3437@2|Bacteria,1UHZZ@1239|Firmicutes,25E8P@186801|Clostridia,25ZUA@186806|Eubacteriaceae	186801|Clostridia	KT	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
HLKFIFDC_02042	411469.EUBHAL_00378	0.0	975.0	COG0635@1|root,COG0635@2|Bacteria,1TREM@1239|Firmicutes,247JT@186801|Clostridia,25V7K@186806|Eubacteriaceae	186801|Clostridia	H	Psort location Cytoplasmic, score	hemZ	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
HLKFIFDC_02043	411469.EUBHAL_00377	2.84e-162	453.0	COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,24JGV@186801|Clostridia,25WHB@186806|Eubacteriaceae	186801|Clostridia	S	Metallo-beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HLKFIFDC_02044	411469.EUBHAL_00376	0.0	1482.0	COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,2489A@186801|Clostridia,25V32@186806|Eubacteriaceae	186801|Clostridia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS16615	ACT_4,HD_4,RelA_SpoT,TGS
HLKFIFDC_02045	411469.EUBHAL_00375	8.38e-98	284.0	COG1781@1|root,COG1781@2|Bacteria,1V6U9@1239|Firmicutes,24JJU@186801|Clostridia,25W8D@186806|Eubacteriaceae	186801|Clostridia	F	Aspartate carbamoyltransferase regulatory chain, allosteric domain	pyrI	-	-	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002	-	-	-	PyrI,PyrI_C
HLKFIFDC_02046	411469.EUBHAL_00374	1.48e-220	608.0	COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,2496D@186801|Clostridia,25V8D@186806|Eubacteriaceae	186801|Clostridia	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N,PyrI_C
HLKFIFDC_02047	411469.EUBHAL_00373	1.26e-218	602.0	COG4866@1|root,COG4866@2|Bacteria,1TR2J@1239|Firmicutes,2480E@186801|Clostridia,25WE6@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K01163	-	-	-	-	ko00000	-	-	-	Acetyltransf_3,DUF2156
HLKFIFDC_02048	411469.EUBHAL_00372	9.68e-296	806.0	COG0538@1|root,COG0538@2|Bacteria,1TSKB@1239|Firmicutes,247KX@186801|Clostridia,25VFN@186806|Eubacteriaceae	186801|Clostridia	C	Belongs to the isocitrate and isopropylmalate dehydrogenases family	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
HLKFIFDC_02049	411469.EUBHAL_00371	1.83e-99	289.0	COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,24J90@186801|Clostridia,25WGK@186806|Eubacteriaceae	186801|Clostridia	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
HLKFIFDC_02050	411469.EUBHAL_02821	0.0	1268.0	COG1404@1|root,COG1404@2|Bacteria,1TQK9@1239|Firmicutes,25B1U@186801|Clostridia,25V8C@186806|Eubacteriaceae	186801|Clostridia	O	Belongs to the peptidase S8 family	cspBA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
HLKFIFDC_02051	411469.EUBHAL_02820	0.0	2223.0	COG1038@1|root,COG1038@2|Bacteria,1UHP9@1239|Firmicutes,25E5B@186801|Clostridia,25ZK1@186806|Eubacteriaceae	186801|Clostridia	C	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second	pyc	-	6.4.1.1	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS18410	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA
HLKFIFDC_02052	411469.EUBHAL_02819	3.02e-176	491.0	COG0289@1|root,COG0289@2|Bacteria,1TR9D@1239|Firmicutes,248FY@186801|Clostridia,25VBP@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS17035	DapB_C,DapB_N
HLKFIFDC_02053	411469.EUBHAL_02818	1.72e-212	587.0	COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,247T5@186801|Clostridia,25VPY@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
HLKFIFDC_02054	411469.EUBHAL_02817	2.03e-117	336.0	COG2109@1|root,COG2109@2|Bacteria,1V82Z@1239|Firmicutes,24J8J@186801|Clostridia,25WXD@186806|Eubacteriaceae	186801|Clostridia	H	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP	btuR	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
HLKFIFDC_02055	411469.EUBHAL_02816	4.47e-295	805.0	COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,24852@186801|Clostridia,25V43@186806|Eubacteriaceae	186801|Clostridia	J	Psort location Cytoplasmic, score 10.00	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
HLKFIFDC_02056	411469.EUBHAL_02815	1.19e-158	444.0	COG0629@1|root,COG0629@2|Bacteria,1TRWZ@1239|Firmicutes,248UD@186801|Clostridia,25V4K@186806|Eubacteriaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	ssb1	-	-	-	-	-	-	-	-	-	-	-	SSB
HLKFIFDC_02057	411469.EUBHAL_02814	0.0	1181.0	COG1217@1|root,COG1217@2|Bacteria,1TQ5Y@1239|Firmicutes,248EB@186801|Clostridia,25UUY@186806|Eubacteriaceae	186801|Clostridia	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2
HLKFIFDC_02058	411469.EUBHAL_02813	3.55e-147	415.0	COG1739@1|root,COG1739@2|Bacteria,1V6MQ@1239|Firmicutes,248W7@186801|Clostridia,25W4W@186806|Eubacteriaceae	186801|Clostridia	S	YigZ family	yvyE	-	-	-	-	-	-	-	-	-	-	-	DUF1949,UPF0029
HLKFIFDC_02061	411469.EUBHAL_00125	2.83e-140	400.0	COG5523@1|root,COG5523@2|Bacteria,1V6FC@1239|Firmicutes,24JPX@186801|Clostridia,25WP4@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	DUF975
HLKFIFDC_02062	411469.EUBHAL_00126	8.03e-229	630.0	COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,248DH@186801|Clostridia,25UQH@186806|Eubacteriaceae	186801|Clostridia	C	Belongs to the LDH MDH superfamily. LDH family	ldh	-	1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	-	R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
HLKFIFDC_02063	411469.EUBHAL_00127	1.32e-39	131.0	COG2200@1|root,COG2200@2|Bacteria	2|Bacteria	T	EAL domain	yliE	GO:0003674,GO:0003824,GO:0008081,GO:0016787,GO:0016788,GO:0042578,GO:0071111	-	-	-	-	-	-	-	-	-	-	CHASE9,EAL,GGDEF,PAS_3,PAS_9
HLKFIFDC_02064	411469.EUBHAL_00128	7.29e-160	446.0	COG2129@1|root,COG2129@2|Bacteria,1V0W0@1239|Firmicutes,24A73@186801|Clostridia,25W5S@186806|Eubacteriaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
HLKFIFDC_02065	411469.EUBHAL_00129	0.0	1243.0	COG1744@1|root,COG1744@2|Bacteria,1VJR1@1239|Firmicutes,25C7B@186801|Clostridia,25UT5@186806|Eubacteriaceae	186801|Clostridia	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	-	-	-	-	-	-	-	-	-	Bmp
HLKFIFDC_02066	1120746.CCNL01000016_gene2337	2.05e-06	51.2	COG2723@1|root,COG2723@2|Bacteria,2NPRZ@2323|unclassified Bacteria	2|Bacteria	G	Glycosyl hydrolase family 1	bglA	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
HLKFIFDC_02067	411469.EUBHAL_00131	5.05e-153	430.0	COG0664@1|root,COG0664@2|Bacteria,1UXDW@1239|Firmicutes	1239|Firmicutes	K	crp fnr family	rcfB	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2
HLKFIFDC_02068	411469.EUBHAL_00132	1.39e-302	826.0	COG3875@1|root,COG3875@2|Bacteria,1TQ1C@1239|Firmicutes,247PH@186801|Clostridia,25V9P@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	5.1.2.1	ko:K22373	ko00620,map00620	-	R01450	RC00519	ko00000,ko00001,ko01000	-	-	-	DUF2088
HLKFIFDC_02069	411469.EUBHAL_00133	1.69e-169	473.0	COG0580@1|root,COG0580@2|Bacteria,1TP4T@1239|Firmicutes,248U5@186801|Clostridia,25WC6@186806|Eubacteriaceae	186801|Clostridia	P	Belongs to the MIP aquaporin (TC 1.A.8) family	glpF	-	-	ko:K02440	-	-	-	-	ko00000,ko02000	1.A.8.1,1.A.8.2	-	-	MIP
HLKFIFDC_02070	411469.EUBHAL_01790	0.0	1030.0	COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia,25VI8@186806|Eubacteriaceae	186801|Clostridia	G	Belongs to the GPI family	pgi	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
HLKFIFDC_02071	411469.EUBHAL_01789	3.03e-196	545.0	29Q1W@1|root,30B0G@2|Bacteria,1W3VE@1239|Firmicutes,2551C@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02072	411469.EUBHAL_01788	4.67e-127	361.0	COG0406@1|root,COG0406@2|Bacteria,1V25J@1239|Firmicutes,24FZT@186801|Clostridia,25W5C@186806|Eubacteriaceae	186801|Clostridia	G	Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
HLKFIFDC_02073	411469.EUBHAL_01786	2.71e-190	528.0	COG1028@1|root,COG1028@2|Bacteria,1TRYD@1239|Firmicutes,248RG@186801|Clostridia,25UQZ@186806|Eubacteriaceae	186801|Clostridia	IQ	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
HLKFIFDC_02075	411469.EUBHAL_01784	0.0	3785.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_3,Cna_B,Collagen_bind,DUF5011,Gram_pos_anchor,MucBP,SdrD_B
HLKFIFDC_02076	411469.EUBHAL_01783	1.64e-115	331.0	COG0440@1|root,COG0440@2|Bacteria,1V3PG@1239|Firmicutes,24A0D@186801|Clostridia,25W3D@186806|Eubacteriaceae	186801|Clostridia	E	ACT domain	ilvH_1	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
HLKFIFDC_02077	411469.EUBHAL_01782	0.0	1155.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,2480U@186801|Clostridia,25VT3@186806|Eubacteriaceae	186801|Clostridia	H	Thiamine pyrophosphate enzyme, central domain	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
HLKFIFDC_02078	411469.EUBHAL_01781	0.0	1506.0	COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,25HJM@186801|Clostridia,25UU8@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
HLKFIFDC_02080	411469.EUBHAL_01779	0.0	1298.0	COG3855@1|root,COG3855@2|Bacteria,1TPFU@1239|Firmicutes,248ZC@186801|Clostridia,25VED@186806|Eubacteriaceae	186801|Clostridia	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3	fbp	-	3.1.3.11	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_2
HLKFIFDC_02081	411469.EUBHAL_01778	0.0	929.0	COG1219@1|root,COG1219@2|Bacteria,1TPDI@1239|Firmicutes,24AEG@186801|Clostridia,25V5F@186806|Eubacteriaceae	186801|Clostridia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX_1	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
HLKFIFDC_02082	411469.EUBHAL_01777	1.24e-164	461.0	COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,248E6@186801|Clostridia,25W3X@186806|Eubacteriaceae	186801|Clostridia	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS20335	IspD
HLKFIFDC_02083	411469.EUBHAL_01776	2.09e-244	671.0	COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,247MG@186801|Clostridia,25V7T@186806|Eubacteriaceae	186801|Clostridia	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
HLKFIFDC_02084	411469.EUBHAL_01775	5.96e-207	572.0	COG1234@1|root,COG1234@2|Bacteria,1TRGP@1239|Firmicutes,248EQ@186801|Clostridia,25VP6@186806|Eubacteriaceae	186801|Clostridia	J	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
HLKFIFDC_02085	411469.EUBHAL_01774	2.24e-52	164.0	2EJD6@1|root,33D47@2|Bacteria,1VKED@1239|Firmicutes,24T7S@186801|Clostridia,25XPY@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02086	411469.EUBHAL_01773	7.09e-101	292.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,24J9Z@186801|Clostridia,25XAS@186806|Eubacteriaceae	186801|Clostridia	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
HLKFIFDC_02087	411469.EUBHAL_01772	3.01e-166	465.0	COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,24A0P@186801|Clostridia,25UTC@186806|Eubacteriaceae	186801|Clostridia	O	Universal bacterial protein YeaZ	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
HLKFIFDC_02088	411469.EUBHAL_01771	1.09e-99	289.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,24MSS@186801|Clostridia,25WM6@186806|Eubacteriaceae	186801|Clostridia	S	Hydrolase, P-loop family	ydiB	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
HLKFIFDC_02089	411469.EUBHAL_01770	5.2e-166	464.0	2AZ5D@1|root,31RC2@2|Bacteria,1V74Z@1239|Firmicutes,24KGW@186801|Clostridia,25XQM@186806|Eubacteriaceae	186801|Clostridia	S	YcxB-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YcxB
HLKFIFDC_02090	411469.EUBHAL_01769	0.0	1350.0	COG2183@1|root,COG2183@2|Bacteria,1TPFE@1239|Firmicutes,248P0@186801|Clostridia,25VB8@186806|Eubacteriaceae	186801|Clostridia	K	Tex-like protein N-terminal domain	yhgF	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
HLKFIFDC_02091	411469.EUBHAL_01768	8.85e-267	730.0	COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,247KU@186801|Clostridia,25V7Q@186806|Eubacteriaceae	186801|Clostridia	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
HLKFIFDC_02092	411469.EUBHAL_01766	0.0	1693.0	COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,247N2@186801|Clostridia,25VEZ@186806|Eubacteriaceae	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
HLKFIFDC_02093	411469.EUBHAL_01764	4.68e-121	345.0	COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,24HDH@186801|Clostridia,25W4P@186806|Eubacteriaceae	186801|Clostridia	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
HLKFIFDC_02094	411469.EUBHAL_01763	3.33e-131	373.0	COG0597@1|root,COG0597@2|Bacteria,1VFDG@1239|Firmicutes,24PUH@186801|Clostridia,25XZM@186806|Eubacteriaceae	186801|Clostridia	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	-	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
HLKFIFDC_02095	411469.EUBHAL_01762	1.5e-182	508.0	COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,248CG@186801|Clostridia,25W47@186806|Eubacteriaceae	186801|Clostridia	P	ABC-type nitrate sulfonate bicarbonate transport system, ATPase component	ssuB_2	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
HLKFIFDC_02096	411469.EUBHAL_01761	1.42e-175	491.0	COG0600@1|root,COG0600@2|Bacteria,1TR6A@1239|Firmicutes,247VM@186801|Clostridia,25ZIP@186806|Eubacteriaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	ssuC_2	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
HLKFIFDC_02097	411469.EUBHAL_01759	4.36e-287	785.0	COG3641@1|root,COG3641@2|Bacteria,1TS5F@1239|Firmicutes,247P0@186801|Clostridia,25VPG@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K07035	-	-	-	-	ko00000	-	-	-	PTS_EIIC_2
HLKFIFDC_02100	411469.EUBHAL_00549	2.93e-280	766.0	COG0013@1|root,COG0013@2|Bacteria,1TSBZ@1239|Firmicutes,249VN@186801|Clostridia,25W97@186806|Eubacteriaceae	186801|Clostridia	J	Threonyl and Alanyl tRNA synthetase second additional domain	alaXL	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
HLKFIFDC_02102	411469.EUBHAL_00547	2.16e-100	293.0	COG0663@1|root,COG0663@2|Bacteria,1V6CZ@1239|Firmicutes,24JAK@186801|Clostridia,25W8Q@186806|Eubacteriaceae	186801|Clostridia	S	Bacterial transferase hexapeptide repeat protein	PaaY	-	-	ko:K02617	-	-	-	-	ko00000	-	-	-	Hexapep,Hexapep_2
HLKFIFDC_02103	411469.EUBHAL_00546	0.0	2974.0	COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,248YB@186801|Clostridia,25VFS@186806|Eubacteriaceae	186801|Clostridia	L	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity	polC	-	2.7.7.7	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
HLKFIFDC_02104	411469.EUBHAL_00545	5.9e-87	258.0	COG3976@1|root,COG3976@2|Bacteria,1V72R@1239|Firmicutes,24JFD@186801|Clostridia,25X5Z@186806|Eubacteriaceae	186801|Clostridia	S	FMN-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02105	411469.EUBHAL_00544	0.0	1289.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1TQ38@1239|Firmicutes,2484Z@186801|Clostridia,25UU5@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
HLKFIFDC_02106	411469.EUBHAL_00543	7.3e-248	682.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,25URK@186806|Eubacteriaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
HLKFIFDC_02107	411469.EUBHAL_00542	1.09e-62	192.0	COG0393@1|root,COG0393@2|Bacteria,1VADM@1239|Firmicutes,24J8R@186801|Clostridia,25WII@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the UPF0145 family	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
HLKFIFDC_02108	411469.EUBHAL_02328	0.0	959.0	COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,248YY@186801|Clostridia,25V3D@186806|Eubacteriaceae	186801|Clostridia	E	Threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS16355	PALP,Thr_synth_N
HLKFIFDC_02109	411469.EUBHAL_02329	5.92e-202	560.0	COG1668@1|root,COG1668@2|Bacteria	2|Bacteria	CP	transmembrane transport	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
HLKFIFDC_02110	411469.EUBHAL_02330	9.57e-213	588.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HLKFIFDC_02111	411469.EUBHAL_02331	0.0	1553.0	2DS24@1|root,33E6B@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02112	411469.EUBHAL_02332	2.41e-245	676.0	COG0642@1|root,COG2205@2|Bacteria,1V129@1239|Firmicutes,25EBE@186801|Clostridia,25ZK6@186806|Eubacteriaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
HLKFIFDC_02113	411469.EUBHAL_02333	4.28e-163	457.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,247TK@186801|Clostridia,25VMJ@186806|Eubacteriaceae	186801|Clostridia	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HLKFIFDC_02114	411469.EUBHAL_02335	5.24e-230	632.0	COG1897@1|root,COG1897@2|Bacteria,1TQVR@1239|Firmicutes,247NP@186801|Clostridia,25VBU@186806|Eubacteriaceae	186801|Clostridia	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metAA	-	2.3.1.46	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	M00017	R01777	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS11970	HTS
HLKFIFDC_02115	411469.EUBHAL_02336	0.0	1263.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,248AX@186801|Clostridia,25UXA@186806|Eubacteriaceae	186801|Clostridia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
HLKFIFDC_02116	411469.EUBHAL_02337	7.18e-194	538.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,248UG@186801|Clostridia,25W0T@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rluF	-	5.4.99.21,5.4.99.22	ko:K06178,ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
HLKFIFDC_02117	411469.EUBHAL_02338	3.66e-85	251.0	COG5496@1|root,COG5496@2|Bacteria,1VAZJ@1239|Firmicutes,24MWR@186801|Clostridia,25WV6@186806|Eubacteriaceae	186801|Clostridia	S	THIoesterase	-	-	3.1.2.29	ko:K18700	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
HLKFIFDC_02118	1232453.BAIF02000033_gene2627	1.9e-174	493.0	COG0524@1|root,COG0524@2|Bacteria,1TPGM@1239|Firmicutes,247M1@186801|Clostridia,26A92@186813|unclassified Clostridiales	186801|Clostridia	G	pfkB family carbohydrate kinase	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
HLKFIFDC_02119	1280698.AUJS01000041_gene2525	6.35e-280	773.0	COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,247UU@186801|Clostridia	186801|Clostridia	G	Glycosyl hydrolase family 32	-	-	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32C,Glyco_hydro_32N
HLKFIFDC_02120	397287.C807_02532	1.02e-289	812.0	COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,247WT@186801|Clostridia,27KRQ@186928|unclassified Lachnospiraceae	186801|Clostridia	G	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1	sacP	-	-	-	-	-	-	-	-	-	-	-	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
HLKFIFDC_02121	1052684.PPM_0727	0.0	929.0	COG3345@1|root,COG3345@2|Bacteria,1TQF4@1239|Firmicutes,4HA5R@91061|Bacilli,26RBH@186822|Paenibacillaceae	91061|Bacilli	G	alpha-galactosidase	galA	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
HLKFIFDC_02122	397287.C807_02533	9.4e-120	351.0	COG2207@1|root,COG2207@2|Bacteria,1V0Z0@1239|Firmicutes,24BNN@186801|Clostridia,27KXW@186928|unclassified Lachnospiraceae	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_AraC
HLKFIFDC_02123	411469.EUBHAL_01598	3.13e-148	419.0	COG0539@1|root,COG0539@2|Bacteria,1UYC5@1239|Firmicutes,24AJ1@186801|Clostridia,25WEN@186806|Eubacteriaceae	186801|Clostridia	J	Ribosomal protein S1-like RNA-binding domain	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
HLKFIFDC_02124	411469.EUBHAL_01068	4.95e-225	622.0	COG0385@1|root,COG0385@2|Bacteria,1TP85@1239|Firmicutes,24A3I@186801|Clostridia,25VF4@186806|Eubacteriaceae	186801|Clostridia	S	Bile acid transporter	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
HLKFIFDC_02125	411469.EUBHAL_01069	8.18e-57	176.0	2DQ38@1|root,334JJ@2|Bacteria,1VJ5Z@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02126	411469.EUBHAL_01071	1.36e-241	664.0	COG1609@1|root,COG1609@2|Bacteria,1TPZJ@1239|Firmicutes,248K0@186801|Clostridia,25VZC@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
HLKFIFDC_02127	411469.EUBHAL_01072	5.1e-302	824.0	COG0153@1|root,COG0153@2|Bacteria,1TPD0@1239|Firmicutes,247U8@186801|Clostridia,25VN6@186806|Eubacteriaceae	186801|Clostridia	G	Belongs to the GHMP kinase family	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
HLKFIFDC_02128	411469.EUBHAL_01073	0.0	1020.0	COG4468@1|root,COG4468@2|Bacteria,1TPBN@1239|Firmicutes,247ZN@186801|Clostridia,25VII@186806|Eubacteriaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
HLKFIFDC_02129	411469.EUBHAL_01074	3.08e-166	465.0	COG4816@1|root,COG4816@2|Bacteria,1TTAA@1239|Firmicutes,2498G@186801|Clostridia,25UYN@186806|Eubacteriaceae	186801|Clostridia	E	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
HLKFIFDC_02130	411469.EUBHAL_01075	4.11e-150	423.0	COG2357@1|root,COG2357@2|Bacteria,1VDTE@1239|Firmicutes,24Q2S@186801|Clostridia,25YTP@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	RelA_SpoT
HLKFIFDC_02131	411469.EUBHAL_01076	1.37e-192	536.0	COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,248QU@186801|Clostridia,25W11@186806|Eubacteriaceae	186801|Clostridia	P	COG0226 ABC-type phosphate transport system, periplasmic component	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
HLKFIFDC_02132	411469.EUBHAL_01077	6.29e-189	526.0	COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,249KQ@186801|Clostridia,25VBN@186806|Eubacteriaceae	186801|Clostridia	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
HLKFIFDC_02133	411469.EUBHAL_01078	1.6e-196	547.0	COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,248C4@186801|Clostridia,25W6J@186806|Eubacteriaceae	186801|Clostridia	P	permease protein	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
HLKFIFDC_02134	411469.EUBHAL_01079	1.2e-175	489.0	COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,247RD@186801|Clostridia,25UW4@186806|Eubacteriaceae	186801|Clostridia	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
HLKFIFDC_02135	411469.EUBHAL_01080	2.38e-140	397.0	COG0704@1|root,COG0704@2|Bacteria,1URN3@1239|Firmicutes,24FTM@186801|Clostridia,25WEB@186806|Eubacteriaceae	186801|Clostridia	P	Plays a role in the regulation of phosphate uptake	phoU	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
HLKFIFDC_02136	411469.EUBHAL_01081	0.0	1115.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,247KT@186801|Clostridia,25V23@186806|Eubacteriaceae	186801|Clostridia	P	Na Pi-cotransporter II-like protein	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
HLKFIFDC_02137	411469.EUBHAL_01082	8.05e-157	440.0	COG0745@1|root,COG0745@2|Bacteria,1TQY9@1239|Firmicutes,24D6A@186801|Clostridia,25V2E@186806|Eubacteriaceae	186801|Clostridia	K	Response regulator receiver domain	phoB	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HLKFIFDC_02138	411469.EUBHAL_01083	4.41e-305	833.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,25UT2@186806|Eubacteriaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,sCache_like
HLKFIFDC_02139	411469.EUBHAL_01085	3.04e-201	558.0	COG0214@1|root,COG0214@2|Bacteria,1TPSZ@1239|Firmicutes,248C1@186801|Clostridia,25VF3@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
HLKFIFDC_02140	411469.EUBHAL_01086	2.75e-130	370.0	COG0311@1|root,COG0311@2|Bacteria,1V3I6@1239|Firmicutes,24HRT@186801|Clostridia,25WAX@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	-	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS19495	SNO
HLKFIFDC_02141	411469.EUBHAL_01087	2.14e-258	708.0	COG3608@1|root,COG3608@2|Bacteria,1UZDT@1239|Firmicutes,24BYA@186801|Clostridia,25W1D@186806|Eubacteriaceae	186801|Clostridia	S	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA,Methyltransf_11
HLKFIFDC_02142	411469.EUBHAL_01088	2.17e-302	827.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,25VVF@186806|Eubacteriaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HLKFIFDC_02143	411469.EUBHAL_01089	4.19e-313	855.0	COG2966@1|root,COG3610@1|root,COG2966@2|Bacteria,COG3610@2|Bacteria,1TNZH@1239|Firmicutes,24BQZ@186801|Clostridia,25VJ6@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ThrE,ThrE_2
HLKFIFDC_02144	411469.EUBHAL_01090	7.48e-193	535.0	28JZH@1|root,2Z9PI@2|Bacteria,1V0QF@1239|Firmicutes,248FG@186801|Clostridia,25WID@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4866
HLKFIFDC_02145	411469.EUBHAL_01091	9.93e-267	729.0	COG1902@1|root,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,25VG3@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
HLKFIFDC_02146	411469.EUBHAL_01092	0.0	1053.0	COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,247NR@186801|Clostridia,25Y2B@186806|Eubacteriaceae	186801|Clostridia	H	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
HLKFIFDC_02148	411469.EUBHAL_01094	0.0	1752.0	COG0480@1|root,COG3688@1|root,COG0480@2|Bacteria,COG3688@2|Bacteria,1TPQH@1239|Firmicutes,247X4@186801|Clostridia,25UXM@186806|Eubacteriaceae	186801|Clostridia	J	Elongation factor G, domain IV	tetP	-	-	-	-	-	-	-	-	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,NYN_YacP
HLKFIFDC_02149	411469.EUBHAL_01095	1.14e-163	458.0	COG0396@1|root,COG0396@2|Bacteria,1TQ98@1239|Firmicutes,2489I@186801|Clostridia,25VGE@186806|Eubacteriaceae	186801|Clostridia	O	FeS assembly ATPase SufC	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
HLKFIFDC_02150	411469.EUBHAL_01096	7.04e-217	598.0	COG0719@1|root,COG0719@2|Bacteria,1TQ21@1239|Firmicutes,249IU@186801|Clostridia,25UUX@186806|Eubacteriaceae	186801|Clostridia	O	Psort location Cytoplasmic, score	-	-	-	ko:K07033	-	-	-	-	ko00000	-	-	-	UPF0051
HLKFIFDC_02151	411469.EUBHAL_01097	6.76e-57	176.0	COG1937@1|root,COG1937@2|Bacteria,1V7GT@1239|Firmicutes,25B4K@186801|Clostridia,25XFE@186806|Eubacteriaceae	186801|Clostridia	S	Metal-sensitive transcriptional repressor	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
HLKFIFDC_02153	411469.EUBHAL_01099	2e-134	380.0	COG1309@1|root,COG1309@2|Bacteria,1V5RP@1239|Firmicutes,24I1Z@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
HLKFIFDC_02154	411469.EUBHAL_01100	1.13e-165	464.0	COG0580@1|root,COG0580@2|Bacteria,1TP4T@1239|Firmicutes,248U5@186801|Clostridia,25WC6@186806|Eubacteriaceae	186801|Clostridia	P	Belongs to the MIP aquaporin (TC 1.A.8) family	glpF	-	-	ko:K02440	-	-	-	-	ko00000,ko02000	1.A.8.1,1.A.8.2	-	-	MIP
HLKFIFDC_02157	411469.EUBHAL_01103	7.13e-101	292.0	COG1959@1|root,COG1959@2|Bacteria,1V3QB@1239|Firmicutes,24JIV@186801|Clostridia,25WZC@186806|Eubacteriaceae	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
HLKFIFDC_02158	411469.EUBHAL_01104	1.24e-208	578.0	COG4905@1|root,COG4905@2|Bacteria,1V2HX@1239|Firmicutes,24B3D@186801|Clostridia,25WVD@186806|Eubacteriaceae	186801|Clostridia	S	CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ABC_trans_CmpB
HLKFIFDC_02159	411469.EUBHAL_01105	1.53e-158	445.0	COG0671@1|root,COG0671@2|Bacteria,1V2ZH@1239|Firmicutes,24HRY@186801|Clostridia,25WEE@186806|Eubacteriaceae	186801|Clostridia	I	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	PAP2,PAP2_3
HLKFIFDC_02160	411469.EUBHAL_01106	9.45e-126	357.0	COG4917@1|root,COG4917@2|Bacteria,1VAYC@1239|Firmicutes,24F8T@186801|Clostridia,25W1X@186806|Eubacteriaceae	186801|Clostridia	E	ethanolamine utilization protein EutP	eutP	-	-	ko:K04029	-	-	-	-	ko00000	-	-	-	PduV-EutP
HLKFIFDC_02161	411469.EUBHAL_01108	1.9e-127	362.0	COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,25VDD@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	rbr3A	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
HLKFIFDC_02163	411469.EUBHAL_01110	1.81e-113	325.0	COG0735@1|root,COG0735@2|Bacteria,1V400@1239|Firmicutes,24JS4@186801|Clostridia,25X07@186806|Eubacteriaceae	186801|Clostridia	P	Belongs to the Fur family	perR	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
HLKFIFDC_02164	411469.EUBHAL_01111	8.1e-44	142.0	COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,24QME@186801|Clostridia,25XFQ@186806|Eubacteriaceae	186801|Clostridia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
HLKFIFDC_02165	411469.EUBHAL_01112	4.41e-222	613.0	COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,247RG@186801|Clostridia,25UZP@186806|Eubacteriaceae	186801|Clostridia	D	Psort location Cytoplasmic, score	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
HLKFIFDC_02166	411469.EUBHAL_01113	0.0	1442.0	COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,247R7@186801|Clostridia,25UUZ@186806|Eubacteriaceae	186801|Clostridia	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
HLKFIFDC_02167	411469.EUBHAL_01114	1.9e-201	557.0	COG1040@1|root,COG1040@2|Bacteria,1VF2G@1239|Firmicutes,24IG6@186801|Clostridia,25WN6@186806|Eubacteriaceae	186801|Clostridia	S	ComF family	comF	-	-	ko:K02242	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	Pribosyltran
HLKFIFDC_02168	411469.EUBHAL_01115	9.67e-104	299.0	COG0756@1|root,COG0756@2|Bacteria,1V5PP@1239|Firmicutes,24I3J@186801|Clostridia,25W99@186806|Eubacteriaceae	186801|Clostridia	F	dUTPase	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
HLKFIFDC_02169	411469.EUBHAL_01118	1.23e-35	121.0	COG0690@1|root,COG0690@2|Bacteria,1U4FZ@1239|Firmicutes,25NAF@186801|Clostridia,25XZS@186806|Eubacteriaceae	186801|Clostridia	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
HLKFIFDC_02170	411469.EUBHAL_01119	2.15e-121	346.0	COG0250@1|root,COG0250@2|Bacteria,1TR3P@1239|Firmicutes,248XB@186801|Clostridia,25VW0@186806|Eubacteriaceae	186801|Clostridia	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
HLKFIFDC_02171	411469.EUBHAL_01120	3.98e-92	270.0	COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,24FSQ@186801|Clostridia,25WDI@186806|Eubacteriaceae	186801|Clostridia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
HLKFIFDC_02172	411469.EUBHAL_01121	3.27e-159	446.0	COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,25VN3@186806|Eubacteriaceae	186801|Clostridia	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
HLKFIFDC_02173	411469.EUBHAL_01547	2.23e-154	437.0	COG0860@1|root,COG0860@2|Bacteria,1UY5Q@1239|Firmicutes,247Y6@186801|Clostridia,25VWY@186806|Eubacteriaceae	186801|Clostridia	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,SH3_3
HLKFIFDC_02174	411469.EUBHAL_01546	0.0	898.0	COG1368@1|root,COG1368@2|Bacteria,1UUVI@1239|Firmicutes,24AGB@186801|Clostridia,25VM5@186806|Eubacteriaceae	186801|Clostridia	M	Sulfatase	-	-	2.7.8.20	ko:K01002	ko01100,map01100	-	-	-	ko00000,ko01000	-	-	-	GBS_Bsp-like,Sulfatase
HLKFIFDC_02175	411469.EUBHAL_01544	1.55e-70	232.0	COG1368@1|root,COG1368@2|Bacteria,1UUVI@1239|Firmicutes,24AGB@186801|Clostridia,25VM5@186806|Eubacteriaceae	186801|Clostridia	M	Sulfatase	-	-	2.7.8.20	ko:K01002	ko01100,map01100	-	-	-	ko00000,ko01000	-	-	-	GBS_Bsp-like,Sulfatase
HLKFIFDC_02176	411469.EUBHAL_01544	0.0	1233.0	COG1368@1|root,COG1368@2|Bacteria,1UUVI@1239|Firmicutes,24AGB@186801|Clostridia,25VM5@186806|Eubacteriaceae	186801|Clostridia	M	Sulfatase	-	-	2.7.8.20	ko:K01002	ko01100,map01100	-	-	-	ko00000,ko01000	-	-	-	GBS_Bsp-like,Sulfatase
HLKFIFDC_02177	411469.EUBHAL_01543	0.0	1251.0	COG0326@1|root,COG0326@2|Bacteria,1TQEU@1239|Firmicutes,247ND@186801|Clostridia,25V71@186806|Eubacteriaceae	186801|Clostridia	O	Molecular chaperone	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
HLKFIFDC_02178	411469.EUBHAL_01542	0.0	1003.0	COG0155@1|root,COG0155@2|Bacteria,1TS58@1239|Firmicutes,248DQ@186801|Clostridia,25UXE@186806|Eubacteriaceae	186801|Clostridia	C	Nitrite/Sulfite reductase ferredoxin-like half domain	nirA	-	1.7.7.1,1.8.7.1	ko:K00366,ko:K00392	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00531	R00790,R00859,R03600	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr,TusA
HLKFIFDC_02179	411469.EUBHAL_01541	8.11e-162	458.0	COG3764@1|root,COG3764@2|Bacteria,1UN9R@1239|Firmicutes,24CEQ@186801|Clostridia,25W9V@186806|Eubacteriaceae	186801|Clostridia	M	(sortase) family	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
HLKFIFDC_02180	411469.EUBHAL_01540	1.52e-302	833.0	COG3266@1|root,COG3266@2|Bacteria,1USV4@1239|Firmicutes,24VT3@186801|Clostridia	186801|Clostridia	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02181	411469.EUBHAL_01539	0.0	1269.0	COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,247P7@186801|Clostridia,25VKD@186806|Eubacteriaceae	186801|Clostridia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
HLKFIFDC_02182	411469.EUBHAL_01538	0.0	1880.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,25USS@186806|Eubacteriaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
HLKFIFDC_02183	411469.EUBHAL_02846	1.55e-243	669.0	COG0502@1|root,COG0502@2|Bacteria,1TPQ4@1239|Firmicutes,248J4@186801|Clostridia,25V8X@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
HLKFIFDC_02184	411469.EUBHAL_01876	2.17e-139	394.0	2C6U1@1|root,30XIE@2|Bacteria,1V4EP@1239|Firmicutes,24J3E@186801|Clostridia,25XNY@186806|Eubacteriaceae	186801|Clostridia	S	Zinc dependent phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
HLKFIFDC_02185	411469.EUBHAL_01878	0.0	1080.0	COG1966@1|root,COG1966@2|Bacteria,1TQN8@1239|Firmicutes,248DZ@186801|Clostridia,25V2R@186806|Eubacteriaceae	186801|Clostridia	T	Carbon starvation protein	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
HLKFIFDC_02186	411469.EUBHAL_01880	2.61e-219	606.0	COG2390@1|root,COG2390@2|Bacteria,1TPUB@1239|Firmicutes,24EXD@186801|Clostridia,25VMS@186806|Eubacteriaceae	186801|Clostridia	K	Putative sugar-binding domain	-	-	-	ko:K05346	-	-	-	-	ko00000,ko03000	-	-	-	Sugar-bind
HLKFIFDC_02187	411469.EUBHAL_01881	4.26e-250	709.0	COG2918@1|root,COG3572@1|root,COG2918@2|Bacteria,COG3572@2|Bacteria,1TPGX@1239|Firmicutes,25ER3@186801|Clostridia,25VNV@186806|Eubacteriaceae	186801|Clostridia	H	Belongs to the glutamate--cysteine ligase type 1 family	gshF	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	Glu_cys_ligase,RimK
HLKFIFDC_02188	411469.EUBHAL_01881	1.39e-302	841.0	COG2918@1|root,COG3572@1|root,COG2918@2|Bacteria,COG3572@2|Bacteria,1TPGX@1239|Firmicutes,25ER3@186801|Clostridia,25VNV@186806|Eubacteriaceae	186801|Clostridia	H	Belongs to the glutamate--cysteine ligase type 1 family	gshF	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	Glu_cys_ligase,RimK
HLKFIFDC_02189	411469.EUBHAL_01882	2.39e-187	521.0	COG0121@1|root,COG0121@2|Bacteria,1V636@1239|Firmicutes,24IUW@186801|Clostridia,25WI8@186806|Eubacteriaceae	186801|Clostridia	S	Glutamine amidotransferases class-II	-	-	-	-	-	-	-	-	-	-	-	-	GATase_4
HLKFIFDC_02190	411469.EUBHAL_01883	1.1e-177	495.0	COG1179@1|root,COG1179@2|Bacteria,1TQ7A@1239|Firmicutes,248RA@186801|Clostridia,25VTH@186806|Eubacteriaceae	186801|Clostridia	H	ThiF family	thiF	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
HLKFIFDC_02191	537007.BLAHAN_04955	1.56e-84	254.0	COG4636@1|root,COG4636@2|Bacteria,1V1Q1@1239|Firmicutes,24G9A@186801|Clostridia,3Y058@572511|Blautia	186801|Clostridia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
HLKFIFDC_02192	697329.Rumal_3660	2.2e-215	600.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia,3WJ00@541000|Ruminococcaceae	186801|Clostridia	L	transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
HLKFIFDC_02195	904296.HMPREF9124_1701	2.39e-51	170.0	2DKVF@1|root,30GMW@2|Bacteria,1TTS8@1239|Firmicutes,257R0@186801|Clostridia,2PTM5@265975|Oribacterium	186801|Clostridia	S	Protein of unknown function (DUF3990)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3990
HLKFIFDC_02197	411469.EUBHAL_00990	3.66e-166	465.0	COG1583@1|root,COG1583@2|Bacteria,1VC7U@1239|Firmicutes,24CJS@186801|Clostridia,25YIH@186806|Eubacteriaceae	186801|Clostridia	L	CRISPR associated protein Cas6	cas6	-	-	ko:K19091	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Cas_Cas6
HLKFIFDC_02198	411469.EUBHAL_00991	0.0	1129.0	28HTI@1|root,2Z80D@2|Bacteria,1TPRZ@1239|Firmicutes,24BPP@186801|Clostridia,25Y1S@186806|Eubacteriaceae	186801|Clostridia	S	CRISPR-associated protein (Cas_CXXC_CXXC)	cst1	-	-	ko:K19088	-	-	-	-	ko00000,ko02048	-	-	-	Cas_CXXC_CXXC
HLKFIFDC_02199	411469.EUBHAL_00992	4.35e-204	565.0	COG1857@1|root,COG1857@2|Bacteria,1TRGS@1239|Firmicutes,24CU1@186801|Clostridia,25Y7R@186806|Eubacteriaceae	186801|Clostridia	L	CRISPR-associated negative auto-regulator DevR/Csa2	cst2	-	-	ko:K19075	-	-	-	-	ko00000,ko02048	-	-	-	DevR
HLKFIFDC_02200	411469.EUBHAL_00993	2.15e-183	509.0	COG1688@1|root,COG1688@2|Bacteria,1UYJD@1239|Firmicutes,24BJA@186801|Clostridia,25YDW@186806|Eubacteriaceae	186801|Clostridia	L	CRISPR-associated protein (Cas_Cas5)	cas5	-	-	ko:K19090	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Cas5d
HLKFIFDC_02201	411469.EUBHAL_00994	0.0	1566.0	COG1203@1|root,COG1203@2|Bacteria,1TQ9B@1239|Firmicutes,248UE@186801|Clostridia,25W5E@186806|Eubacteriaceae	186801|Clostridia	L	DEAD-like helicases superfamily	cas3	-	-	ko:K07012	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DEAD,HD,Helicase_C,ResIII
HLKFIFDC_02202	411469.EUBHAL_00995	7.11e-115	329.0	COG1468@1|root,COG1468@2|Bacteria,1V781@1239|Firmicutes,24IBG@186801|Clostridia,25WPK@186806|Eubacteriaceae	186801|Clostridia	L	Domain of unknown function DUF83	cas4	-	3.1.12.1	ko:K07464	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Cas_Cas4
HLKFIFDC_02203	411469.EUBHAL_00997	1.35e-238	655.0	COG1518@1|root,COG1518@2|Bacteria,1TQWG@1239|Firmicutes,24889@186801|Clostridia,25VR4@186806|Eubacteriaceae	186801|Clostridia	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas1	-	-	ko:K15342	-	-	-	-	ko00000,ko02048,ko03400	-	-	-	Cas_Cas1
HLKFIFDC_02204	411469.EUBHAL_00998	1.99e-62	191.0	COG1343@1|root,COG1343@2|Bacteria,1VAV3@1239|Firmicutes,24NM2@186801|Clostridia,25XM3@186806|Eubacteriaceae	186801|Clostridia	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas2	-	-	ko:K09951	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cas2
HLKFIFDC_02205	411469.EUBHAL_00999	8.24e-43	139.0	COG1724@1|root,COG1724@2|Bacteria,1VG73@1239|Firmicutes,24RPN@186801|Clostridia,25Z14@186806|Eubacteriaceae	186801|Clostridia	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
HLKFIFDC_02206	411469.EUBHAL_01000	6.58e-101	292.0	COG1598@1|root,COG1598@2|Bacteria,1V1WA@1239|Firmicutes,24KX5@186801|Clostridia,25XN2@186806|Eubacteriaceae	186801|Clostridia	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
HLKFIFDC_02207	411469.EUBHAL_01002	6.95e-58	179.0	2ETJQ@1|root,33M3G@2|Bacteria,1VMD5@1239|Firmicutes,24WQN@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02208	411469.EUBHAL_01003	6.23e-76	226.0	arCOG09714@1|root,316P9@2|Bacteria,1V7WP@1239|Firmicutes,24K29@186801|Clostridia,25XRA@186806|Eubacteriaceae	186801|Clostridia	S	COG NOG16854 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02209	411469.EUBHAL_01004	4.53e-45	145.0	2EIT0@1|root,33CIB@2|Bacteria,1VNT8@1239|Firmicutes,24WHF@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02210	411469.EUBHAL_01005	2.83e-53	167.0	COG3326@1|root,COG3326@2|Bacteria,1VEJY@1239|Firmicutes,24QJW@186801|Clostridia,25XSB@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF1294)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1294
HLKFIFDC_02211	411469.EUBHAL_01006	2.18e-132	375.0	COG1451@1|root,COG1451@2|Bacteria,1V6WP@1239|Firmicutes,24JGH@186801|Clostridia,25WCZ@186806|Eubacteriaceae	186801|Clostridia	S	WLM domain	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
HLKFIFDC_02212	411469.EUBHAL_01007	3.72e-237	652.0	28K5V@1|root,2Z9UD@2|Bacteria,1V0GM@1239|Firmicutes,24EZ5@186801|Clostridia,25VNB@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3878
HLKFIFDC_02213	411469.EUBHAL_01008	2.43e-130	371.0	COG1595@1|root,COG1595@2|Bacteria,1VCZT@1239|Firmicutes	1239|Firmicutes	K	Belongs to the sigma-70 factor family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HLKFIFDC_02214	411469.EUBHAL_01009	1.98e-314	857.0	2CDM8@1|root,32RY0@2|Bacteria,1VDQE@1239|Firmicutes,24HQE@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Sigma_reg_C
HLKFIFDC_02215	411469.EUBHAL_01011	0.0	1148.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia,25UYJ@186806|Eubacteriaceae	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
HLKFIFDC_02216	411469.EUBHAL_01013	5.94e-161	450.0	COG0177@1|root,COG0177@2|Bacteria,1TRAK@1239|Firmicutes,24899@186801|Clostridia,25V09@186806|Eubacteriaceae	186801|Clostridia	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
HLKFIFDC_02217	411469.EUBHAL_01014	1.31e-217	599.0	COG0152@1|root,COG0152@2|Bacteria,1TP11@1239|Firmicutes,2483I@186801|Clostridia,25VFG@186806|Eubacteriaceae	186801|Clostridia	F	Belongs to the SAICAR synthetase family	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
HLKFIFDC_02218	411469.EUBHAL_01015	0.0	909.0	2A9Y5@1|root,30Z6B@2|Bacteria,1V4NV@1239|Firmicutes,24I4G@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02219	411469.EUBHAL_01016	5.06e-260	712.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,24BJ8@186801|Clostridia,25W9R@186806|Eubacteriaceae	186801|Clostridia	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
HLKFIFDC_02220	411469.EUBHAL_01017	5.51e-255	699.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,24BJ8@186801|Clostridia,25W9R@186806|Eubacteriaceae	186801|Clostridia	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,PASTA,PDZ_2,Pkinase,YARHG
HLKFIFDC_02222	411469.EUBHAL_01019	1.1e-233	645.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new,LRR_5
HLKFIFDC_02223	411469.EUBHAL_01020	1.43e-46	163.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,24BJ8@186801|Clostridia,25W9R@186806|Eubacteriaceae	186801|Clostridia	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
HLKFIFDC_02224	411469.EUBHAL_01020	0.0	971.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,24BJ8@186801|Clostridia,25W9R@186806|Eubacteriaceae	186801|Clostridia	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
HLKFIFDC_02230	411469.EUBHAL_00070	7.43e-277	758.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,25VH5@186806|Eubacteriaceae	186801|Clostridia	I	Belongs to the thiolase family	thlA	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
HLKFIFDC_02231	411469.EUBHAL_00071	9.39e-184	511.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,25UX1@186806|Eubacteriaceae	186801|Clostridia	I	Belongs to the enoyl-CoA hydratase isomerase family	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
HLKFIFDC_02232	411469.EUBHAL_00072	7.19e-197	546.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,25V6P@186806|Eubacteriaceae	186801|Clostridia	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	hbd	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
HLKFIFDC_02233	411469.EUBHAL_00073	7.05e-271	742.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,25USM@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	bcd	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
HLKFIFDC_02234	411469.EUBHAL_00074	9.78e-186	516.0	COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,25UTI@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	etfB	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016627,GO:0016628,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363	1.3.1.108	ko:K03521,ko:K22431	-	-	-	-	ko00000,ko01000	-	-	-	ETF
HLKFIFDC_02235	411469.EUBHAL_00075	1.57e-245	675.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,25UTQ@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	etfA	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016627,GO:0016628,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363	1.3.1.108	ko:K03522,ko:K22432	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	ETF,ETF_alpha,Fer4
HLKFIFDC_02237	411469.EUBHAL_00351	9.23e-65	197.0	COG4842@1|root,COG4842@2|Bacteria,1VGZJ@1239|Firmicutes,24SEZ@186801|Clostridia,25XDQ@186806|Eubacteriaceae	186801|Clostridia	S	Proteins of 100 residues with WXG	-	-	-	-	-	-	-	-	-	-	-	-	WXG100
HLKFIFDC_02238	411469.EUBHAL_00352	2.8e-169	473.0	COG3279@1|root,COG3279@2|Bacteria,1VD3A@1239|Firmicutes,24MP2@186801|Clostridia,25YVR@186806|Eubacteriaceae	186801|Clostridia	K	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR
HLKFIFDC_02239	411469.EUBHAL_00353	0.0	898.0	COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,247V0@186801|Clostridia,25VHE@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	cat	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
HLKFIFDC_02240	411469.EUBHAL_00354	7.55e-242	665.0	COG3081@1|root,COG3081@2|Bacteria,1TSR5@1239|Firmicutes,25CG3@186801|Clostridia,25WHK@186806|Eubacteriaceae	186801|Clostridia	S	37-kD nucleoid-associated bacterial protein	-	-	-	-	-	-	-	-	-	-	-	-	NA37
HLKFIFDC_02241	411469.EUBHAL_00355	0.0	2536.0	COG1674@1|root,COG1716@1|root,COG1674@2|Bacteria,COG1716@2|Bacteria,1TRA4@1239|Firmicutes,249Z1@186801|Clostridia,25V6X@186806|Eubacteriaceae	186801|Clostridia	D	Type VII secretion protein EssC	essC	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FHA,FtsK_SpoIIIE
HLKFIFDC_02243	411469.EUBHAL_00357	0.0	1144.0	COG0515@1|root,COG0515@2|Bacteria,1TPYP@1239|Firmicutes,24ABN@186801|Clostridia,25W8G@186806|Eubacteriaceae	186801|Clostridia	KLT	Kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
HLKFIFDC_02244	411469.EUBHAL_00358	0.0	2192.0	COG3188@1|root,COG3188@2|Bacteria	411469.EUBHAL_00358|-	NU	fimbrial usher porin activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02245	411469.EUBHAL_00360	4.99e-41	135.0	COG4481@1|root,COG4481@2|Bacteria,1VEQ7@1239|Firmicutes,24QKA@186801|Clostridia,25X9G@186806|Eubacteriaceae	186801|Clostridia	S	Bacterial protein of unknown function (DUF951)	-	-	-	-	-	-	-	-	-	-	-	-	DUF951
HLKFIFDC_02246	411469.EUBHAL_00361	4.65e-63	192.0	COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,24QZQ@186801|Clostridia,25WPC@186806|Eubacteriaceae	186801|Clostridia	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
HLKFIFDC_02247	411469.EUBHAL_00362	4.68e-92	271.0	COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,24HF9@186801|Clostridia,25WQN@186806|Eubacteriaceae	186801|Clostridia	L	Single-stranded DNA-binding protein	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
HLKFIFDC_02248	411469.EUBHAL_00363	7.84e-55	171.0	COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,24MQV@186801|Clostridia,25WV7@186806|Eubacteriaceae	186801|Clostridia	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
HLKFIFDC_02249	411469.EUBHAL_00364	1.22e-88	260.0	COG1869@1|root,COG1869@2|Bacteria,1VA2V@1239|Firmicutes,24MPJ@186801|Clostridia,25Z18@186806|Eubacteriaceae	186801|Clostridia	G	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose	rbsD	-	5.4.99.62	ko:K06726	ko02010,map02010	-	R08247	RC02247	ko00000,ko00001,ko01000	-	-	-	RbsD_FucU
HLKFIFDC_02250	411469.EUBHAL_00365	8.99e-201	556.0	COG1451@1|root,COG1451@2|Bacteria	2|Bacteria	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
HLKFIFDC_02251	411469.EUBHAL_00366	0.0	1058.0	COG1194@1|root,COG3663@1|root,COG1194@2|Bacteria,COG3663@2|Bacteria,1TPUT@1239|Firmicutes,25E4K@186801|Clostridia,25VGT@186806|Eubacteriaceae	186801|Clostridia	L	NUDIX domain	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4,SfsA
HLKFIFDC_02252	411469.EUBHAL_00367	8.82e-202	557.0	COG1234@1|root,COG1234@2|Bacteria,1TPSW@1239|Firmicutes,249RR@186801|Clostridia,25V4U@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
HLKFIFDC_02253	411469.EUBHAL_00368	2.13e-183	510.0	COG0106@1|root,COG0106@2|Bacteria,1TPIN@1239|Firmicutes,249HJ@186801|Clostridia,25UWU@186806|Eubacteriaceae	186801|Clostridia	E	Belongs to the HisA HisF family	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
HLKFIFDC_02254	411469.EUBHAL_00369	5.05e-278	761.0	COG2073@1|root,COG2073@2|Bacteria,1TPYM@1239|Firmicutes,247JW@186801|Clostridia,25W84@186806|Eubacteriaceae	186801|Clostridia	H	Cobalamin synthesis G C-terminus	cbiG	-	3.7.1.12	ko:K02189	ko00860,ko01100,map00860,map01100	-	R07772	RC01545,RC02097	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS15705	CbiG_C,CbiG_N,CbiG_mid
HLKFIFDC_02255	411469.EUBHAL_00370	6.55e-115	329.0	COG3760@1|root,COG3760@2|Bacteria,1V29H@1239|Firmicutes,25D4W@186801|Clostridia,25XJ9@186806|Eubacteriaceae	186801|Clostridia	S	YbaK proline--tRNA ligase associated domain protein	-	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
HLKFIFDC_02256	411469.EUBHAL_00035	2.85e-154	434.0	COG3201@1|root,COG3201@2|Bacteria,1V21G@1239|Firmicutes,24CVF@186801|Clostridia	186801|Clostridia	H	nicotinamide mononucleotide transporter	pnuC	-	-	-	-	-	-	-	-	-	-	-	NMN_transporter
HLKFIFDC_02257	411469.EUBHAL_00034	5.01e-126	358.0	COG0778@1|root,COG0778@2|Bacteria,1V4K6@1239|Firmicutes,24B09@186801|Clostridia,25W8E@186806|Eubacteriaceae	186801|Clostridia	C	Nitroreductase family	nfrA2	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
HLKFIFDC_02258	411469.EUBHAL_00033	2.46e-48	154.0	COG1396@1|root,COG1396@2|Bacteria,1VDA0@1239|Firmicutes,24PY4@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
HLKFIFDC_02259	411469.EUBHAL_00032	5.55e-154	431.0	COG1898@1|root,COG1898@2|Bacteria,1TRVB@1239|Firmicutes,248VX@186801|Clostridia,25VZ4@186806|Eubacteriaceae	186801|Clostridia	G	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS02630,iHN637.CLJU_RS02745	dTDP_sugar_isom
HLKFIFDC_02260	411469.EUBHAL_00031	5.47e-234	642.0	COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,247PG@186801|Clostridia,25VU6@186806|Eubacteriaceae	186801|Clostridia	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133,5.1.3.13	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777,R06514	RC00182,RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
HLKFIFDC_02261	411469.EUBHAL_00030	4.49e-262	716.0	COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,247NE@186801|Clostridia,25VJ0@186806|Eubacteriaceae	186801|Clostridia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
HLKFIFDC_02262	411469.EUBHAL_00029	3.5e-218	601.0	COG1209@1|root,COG1209@2|Bacteria,1V301@1239|Firmicutes,247XE@186801|Clostridia,25UUW@186806|Eubacteriaceae	186801|Clostridia	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
HLKFIFDC_02263	411469.EUBHAL_00028	1.2e-208	577.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1TSRS@1239|Firmicutes,24BXX@186801|Clostridia,25VXD@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18,HTH_AraC
HLKFIFDC_02264	411469.EUBHAL_00027	0.0	1479.0	COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,25KHW@186801|Clostridia,25USX@186806|Eubacteriaceae	186801|Clostridia	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
HLKFIFDC_02265	411469.EUBHAL_00026	0.0	1313.0	COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,247ZA@186801|Clostridia,25UY4@186806|Eubacteriaceae	186801|Clostridia	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
HLKFIFDC_02266	411469.EUBHAL_00025	2.11e-310	845.0	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,248II@186801|Clostridia,25VID@186806|Eubacteriaceae	186801|Clostridia	H	Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
HLKFIFDC_02267	411469.EUBHAL_00024	1.62e-174	487.0	COG2875@1|root,COG2875@2|Bacteria,1TP6J@1239|Firmicutes,248IZ@186801|Clostridia,25V19@186806|Eubacteriaceae	186801|Clostridia	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	cobM	-	2.1.1.133,2.1.1.271	ko:K05936	ko00860,ko01100,map00860,map01100	-	R05181,R05810	RC00003,RC01294,RC02049	ko00000,ko00001,ko01000	-	-	-	TP_methylase
HLKFIFDC_02268	411469.EUBHAL_00023	2.5e-279	764.0	COG0373@1|root,COG0373@2|Bacteria,1TQN9@1239|Firmicutes,2496M@186801|Clostridia,25VG7@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
HLKFIFDC_02269	411469.EUBHAL_00022	1.56e-177	494.0	COG1010@1|root,COG1010@2|Bacteria,1TPJ7@1239|Firmicutes,247QS@186801|Clostridia,25V3N@186806|Eubacteriaceae	186801|Clostridia	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	cobJ	-	2.1.1.131,2.1.1.272	ko:K05934,ko:K21479	ko00860,ko01100,map00860,map01100	-	R05180,R05809,R11580	RC00003,RC01293,RC03471,RC03479	ko00000,ko00001,ko01000	-	-	-	TP_methylase
HLKFIFDC_02270	411469.EUBHAL_00021	0.0	1615.0	COG0007@1|root,COG0181@1|root,COG0007@2|Bacteria,COG0181@2|Bacteria,1TQNH@1239|Firmicutes,2487I@186801|Clostridia,25V51@186806|Eubacteriaceae	186801|Clostridia	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	cobA	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS15755	HEM4,Porphobil_deam,Porphobil_deamC,TP_methylase
HLKFIFDC_02271	411469.EUBHAL_00020	9.5e-167	468.0	COG0368@1|root,COG0368@2|Bacteria,1V1QB@1239|Firmicutes,24I0D@186801|Clostridia	186801|Clostridia	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
HLKFIFDC_02272	411469.EUBHAL_00019	3.25e-253	694.0	COG2038@1|root,COG2038@2|Bacteria,1TPC1@1239|Firmicutes,25DH5@186801|Clostridia,25VHG@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	-	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT
HLKFIFDC_02273	411469.EUBHAL_00018	7.22e-149	419.0	COG2082@1|root,COG2082@2|Bacteria,1V1SX@1239|Firmicutes,24B9Z@186801|Clostridia,25W34@186806|Eubacteriaceae	186801|Clostridia	H	Precorrin-8X methylmutase	cobH	-	5.4.99.60,5.4.99.61	ko:K06042	ko00860,ko01100,map00860,map01100	-	R05177,R05814	RC01292,RC01980	ko00000,ko00001,ko01000	-	-	-	CbiC
HLKFIFDC_02274	411469.EUBHAL_00017	7.13e-255	699.0	COG1903@1|root,COG1903@2|Bacteria,1TQ3M@1239|Firmicutes,248AK@186801|Clostridia,25UST@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A	cbiD	-	2.1.1.195	ko:K02188	ko00860,ko01100,map00860,map01100	-	R07773	RC00003,RC02051	ko00000,ko00001,ko01000	-	-	-	CbiD
HLKFIFDC_02275	411469.EUBHAL_00016	1.85e-301	822.0	COG2241@1|root,COG2242@1|root,COG2241@2|Bacteria,COG2242@2|Bacteria,1TS3H@1239|Firmicutes,2483G@186801|Clostridia,25W2I@186806|Eubacteriaceae	186801|Clostridia	H	precorrin-6y C5,15-methyltransferase	cbiT	-	2.1.1.132,2.1.1.196	ko:K00595,ko:K02191	ko00860,ko01100,map00860,map01100	-	R05149,R05813,R07774	RC00003,RC01279,RC02052,RC02054	ko00000,ko00001,ko01000	-	-	-	CbiJ,Cons_hypoth95,MTS,Met_10,Methyltransf_31,Methyltransf_4,PCMT,TP_methylase
HLKFIFDC_02276	411469.EUBHAL_00015	8.47e-186	516.0	COG4822@1|root,COG4822@2|Bacteria,1TQ5V@1239|Firmicutes,24ABG@186801|Clostridia,25W2F@186806|Eubacteriaceae	186801|Clostridia	H	Cobalt chelatase (CbiK)	cbiK	-	4.99.1.3	ko:K02190	ko00860,ko01100,map00860,map01100	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiK
HLKFIFDC_02277	411469.EUBHAL_00014	6.59e-160	448.0	COG2243@1|root,COG2243@2|Bacteria,1TP87@1239|Firmicutes,249DM@186801|Clostridia,25W9U@186806|Eubacteriaceae	186801|Clostridia	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	cobI	-	2.1.1.130,2.1.1.151	ko:K03394	ko00860,ko01100,map00860,map01100	-	R03948,R05808	RC00003,RC01035,RC01662	ko00000,ko00001,ko01000	-	-	-	TP_methylase
HLKFIFDC_02278	411469.EUBHAL_00013	1.49e-164	461.0	COG2099@1|root,COG2099@2|Bacteria,1UHWY@1239|Firmicutes,24GIQ@186801|Clostridia,25W9J@186806|Eubacteriaceae	186801|Clostridia	H	Precorrin-6x reductase CbiJ/CobK	cobK	-	1.3.1.106,1.3.1.54	ko:K05895	ko00860,ko01100,map00860,map01100	-	R05150,R05812	RC01280	ko00000,ko00001,ko01000	-	-	-	CbiJ
HLKFIFDC_02279	411469.EUBHAL_00012	0.0	941.0	COG1797@1|root,COG1797@2|Bacteria,1TNY2@1239|Firmicutes,247PU@186801|Clostridia,25UZ5@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	AAA_26,CbiA,GATase_3
HLKFIFDC_02280	411469.EUBHAL_00011	1.76e-232	640.0	COG1270@1|root,COG1270@2|Bacteria,1TQ3X@1239|Firmicutes,247PR@186801|Clostridia,25UVZ@186806|Eubacteriaceae	186801|Clostridia	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
HLKFIFDC_02281	411469.EUBHAL_00010	5.9e-258	707.0	COG0079@1|root,COG0079@2|Bacteria,1TP5D@1239|Firmicutes,248Q0@186801|Clostridia,25UXQ@186806|Eubacteriaceae	186801|Clostridia	E	Cytoplasmic, score	cobD_2	-	4.1.1.81	ko:K04720	ko00860,map00860	-	R06530	RC00517	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
HLKFIFDC_02282	411469.EUBHAL_00009	0.0	1338.0	COG1492@1|root,COG2109@1|root,COG1492@2|Bacteria,COG2109@2|Bacteria,1TP5E@1239|Firmicutes,248XW@186801|Clostridia,25VJ2@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS15780	AAA_26,CbiA,GATase_3
HLKFIFDC_02283	411469.EUBHAL_00008	1.1e-193	538.0	COG1648@1|root,COG1648@2|Bacteria,1VA2E@1239|Firmicutes,24N6M@186801|Clostridia,25X6M@186806|Eubacteriaceae	186801|Clostridia	H	Putative NAD(P)-binding	cysG	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M
HLKFIFDC_02284	411469.EUBHAL_00007	1.33e-100	291.0	COG0454@1|root,COG0454@2|Bacteria,1VD9I@1239|Firmicutes,24MT9@186801|Clostridia,25X3U@186806|Eubacteriaceae	186801|Clostridia	K	Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
HLKFIFDC_02285	411469.EUBHAL_00006	6.66e-233	641.0	COG0113@1|root,COG0113@2|Bacteria,1TP09@1239|Firmicutes,2496V@186801|Clostridia,25V13@186806|Eubacteriaceae	186801|Clostridia	H	Delta-aminolevulinic acid dehydratase	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS15750	ALAD
HLKFIFDC_02286	411469.EUBHAL_02988	1.83e-49	157.0	COG1918@1|root,COG1918@2|Bacteria,1VEHC@1239|Firmicutes,24QKE@186801|Clostridia,25XJX@186806|Eubacteriaceae	186801|Clostridia	P	FeoA	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
HLKFIFDC_02287	411469.EUBHAL_02989	0.0	1274.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,24885@186801|Clostridia,25V92@186806|Eubacteriaceae	186801|Clostridia	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
HLKFIFDC_02288	411469.EUBHAL_02990	4.29e-89	262.0	COG1585@1|root,COG1585@2|Bacteria,1VAS9@1239|Firmicutes,24MRQ@186801|Clostridia,25XIA@186806|Eubacteriaceae	186801|Clostridia	OU	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
HLKFIFDC_02289	411469.EUBHAL_02991	2.24e-148	426.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia,25VEF@186806|Eubacteriaceae	186801|Clostridia	O	SPFH Band 7 PHB domain protein	qmcA	-	-	-	-	-	-	-	-	-	-	-	Band_7
HLKFIFDC_02290	411469.EUBHAL_02992	0.0	1283.0	COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,2480C@186801|Clostridia,25XJQ@186806|Eubacteriaceae	186801|Clostridia	M	Sulfatase	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
HLKFIFDC_02291	411469.EUBHAL_01220	2.72e-237	652.0	COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,248I5@186801|Clostridia,25UXW@186806|Eubacteriaceae	186801|Clostridia	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12430	OTCace,OTCace_N
HLKFIFDC_02292	411469.EUBHAL_01221	2.05e-231	637.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,248CK@186801|Clostridia,25W5K@186806|Eubacteriaceae	186801|Clostridia	H	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
HLKFIFDC_02293	411469.EUBHAL_01222	7.86e-77	229.0	2CJXG@1|root,32SB0@2|Bacteria,1VAFJ@1239|Firmicutes,24MNI@186801|Clostridia,25WWT@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02294	411469.EUBHAL_01223	3.99e-183	509.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,248PX@186801|Clostridia,25VB2@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
HLKFIFDC_02295	411469.EUBHAL_01224	4.3e-228	628.0	COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,248HD@186801|Clostridia,25VHB@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
HLKFIFDC_02296	411469.EUBHAL_01225	2.76e-99	289.0	COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,24HP9@186801|Clostridia,25W38@186806|Eubacteriaceae	186801|Clostridia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
HLKFIFDC_02297	1410632.JHWW01000006_gene694	2.21e-10	62.0	2DIZ6@1|root,32UC0@2|Bacteria,1VGDB@1239|Firmicutes,24SFK@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02298	411469.EUBHAL_01227	1.42e-223	618.0	28K89@1|root,2Z9W3@2|Bacteria,1V1PZ@1239|Firmicutes,24D2W@186801|Clostridia,25WDJ@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02299	411469.EUBHAL_01228	6.14e-204	565.0	COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,249K8@186801|Clostridia,25V6R@186806|Eubacteriaceae	186801|Clostridia	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
HLKFIFDC_02300	411469.EUBHAL_01229	1.07e-284	779.0	COG4856@1|root,COG4856@2|Bacteria,1TSIV@1239|Firmicutes,24GKC@186801|Clostridia,25W2Z@186806|Eubacteriaceae	186801|Clostridia	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
HLKFIFDC_02301	411469.EUBHAL_01230	4.87e-123	350.0	COG1309@1|root,COG1309@2|Bacteria,1V890@1239|Firmicutes	1239|Firmicutes	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
HLKFIFDC_02302	411469.EUBHAL_01231	1.62e-182	508.0	COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,248DV@186801|Clostridia,25W0K@186806|Eubacteriaceae	186801|Clostridia	J	RNA methyltransferase TrmH family	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
HLKFIFDC_02303	411469.EUBHAL_01232	0.0	1024.0	COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,25VA2@186806|Eubacteriaceae	186801|Clostridia	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
HLKFIFDC_02304	411469.EUBHAL_02039	6.13e-128	363.0	28PZ1@1|root,2ZCII@2|Bacteria,1V2GX@1239|Firmicutes,24IE1@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3877
HLKFIFDC_02305	411469.EUBHAL_02040	5.07e-235	646.0	COG2755@1|root,COG2755@2|Bacteria,1V254@1239|Firmicutes,24J71@186801|Clostridia	186801|Clostridia	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02306	411469.EUBHAL_02041	0.0	1062.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,248V4@186801|Clostridia,25V5N@186806|Eubacteriaceae	186801|Clostridia	M	membrane protein involved in D-alanine export	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
HLKFIFDC_02307	411469.EUBHAL_02042	2.25e-45	146.0	COG0236@1|root,COG0236@2|Bacteria,1VEX6@1239|Firmicutes,24QWP@186801|Clostridia,25X76@186806|Eubacteriaceae	186801|Clostridia	IQ	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
HLKFIFDC_02308	411469.EUBHAL_02043	0.0	1050.0	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,2490U@186801|Clostridia,25V6D@186806|Eubacteriaceae	186801|Clostridia	Q	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
HLKFIFDC_02310	411469.EUBHAL_03105	7.07e-222	612.0	COG2390@1|root,COG2390@2|Bacteria,1TPUB@1239|Firmicutes,25D2S@186801|Clostridia,25V5X@186806|Eubacteriaceae	186801|Clostridia	K	sugar-binding domain protein	sorC1	-	-	-	-	-	-	-	-	-	-	-	HTH_24,HTH_Crp_2,Sigma70_r4,Sugar-bind
HLKFIFDC_02311	411469.EUBHAL_03104	2.16e-289	790.0	COG0371@1|root,COG0371@2|Bacteria,1TR6W@1239|Firmicutes,25CDJ@186801|Clostridia,25VAJ@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	1.1.1.261	ko:K00096	ko00564,map00564	-	R05679,R05680	RC00029	ko00000,ko00001,ko01000	-	-	-	Fe-ADH_2,Hydrolase_6,Hydrolase_like
HLKFIFDC_02312	411469.EUBHAL_02938	3.72e-196	543.0	COG0647@1|root,COG0647@2|Bacteria,1TQGM@1239|Firmicutes,24B6W@186801|Clostridia,25USK@186806|Eubacteriaceae	186801|Clostridia	G	Haloacid dehalogenase-like hydrolase	-	-	3.1.3.41	ko:K01101,ko:K02566	ko00627,ko01120,map00627,map01120	-	R03024	RC00151	ko00000,ko00001,ko01000	-	-	-	Hydrolase_6,Hydrolase_like
HLKFIFDC_02313	411469.EUBHAL_02937	5.17e-99	287.0	COG0698@1|root,COG0698@2|Bacteria,1V2VV@1239|Firmicutes,24GCM@186801|Clostridia,25W2Y@186806|Eubacteriaceae	186801|Clostridia	G	Ribose/Galactose Isomerase	-	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
HLKFIFDC_02314	411469.EUBHAL_02936	0.0	1068.0	COG1069@1|root,COG1069@2|Bacteria,1UHVR@1239|Firmicutes,25E4P@186801|Clostridia,25V3I@186806|Eubacteriaceae	186801|Clostridia	H	Belongs to the FGGY kinase family	-	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
HLKFIFDC_02315	411469.EUBHAL_02935	5.47e-103	298.0	COG0698@1|root,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,24JWT@186801|Clostridia,25WQ2@186806|Eubacteriaceae	186801|Clostridia	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
HLKFIFDC_02316	411469.EUBHAL_02934	8.92e-94	273.0	2DQ52@1|root,334SU@2|Bacteria,1VFI1@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
HLKFIFDC_02317	411469.EUBHAL_00346	3.04e-313	855.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,25UUM@186806|Eubacteriaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HLKFIFDC_02318	411462.DORLON_01191	2.22e-114	338.0	COG0583@1|root,COG0583@2|Bacteria,1UXFR@1239|Firmicutes,25C6Q@186801|Clostridia	186801|Clostridia	K	transcriptional regulator	-	-	-	ko:K21755	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
HLKFIFDC_02320	411469.EUBHAL_01860	3.08e-128	365.0	COG1961@1|root,COG1961@2|Bacteria,1V51N@1239|Firmicutes,24D8I@186801|Clostridia,25XGG@186806|Eubacteriaceae	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_7,Resolvase
HLKFIFDC_02321	411469.EUBHAL_01861	2.04e-277	761.0	COG1301@1|root,COG1301@2|Bacteria,1TPME@1239|Firmicutes,247UX@186801|Clostridia,25UR9@186806|Eubacteriaceae	186801|Clostridia	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltT	-	-	-	-	-	-	-	-	-	-	-	SDF
HLKFIFDC_02322	411469.EUBHAL_01862	3.54e-311	850.0	COG0534@1|root,COG0534@2|Bacteria,1TP5P@1239|Firmicutes,247PQ@186801|Clostridia,25VG0@186806|Eubacteriaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HLKFIFDC_02323	411469.EUBHAL_01863	6.94e-126	359.0	COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249VD@186801|Clostridia,25WCD@186806|Eubacteriaceae	186801|Clostridia	F	Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
HLKFIFDC_02324	411469.EUBHAL_01865	0.0	1321.0	COG0642@1|root,COG3452@1|root,COG0642@2|Bacteria,COG3452@2|Bacteria,1UYZX@1239|Firmicutes,25E9T@186801|Clostridia,25ZJZ@186806|Eubacteriaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,FIST,FIST_C,HATPase_c,HisKA,Response_reg,dCache_1
HLKFIFDC_02325	411469.EUBHAL_01866	4.63e-212	589.0	COG2390@1|root,COG2390@2|Bacteria,1TPUB@1239|Firmicutes,24DHE@186801|Clostridia	186801|Clostridia	K	Putative sugar-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,Sigma70_r4,Sigma70_r4_2,Sugar-bind
HLKFIFDC_02326	457412.RSAG_03473	7.63e-290	803.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,3WHR7@541000|Ruminococcaceae	186801|Clostridia	E	Aminotransferase class I and II	-	-	2.6.1.2,2.6.1.66	ko:K14260	ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230	-	R00258,R01215	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2,HTH_3
HLKFIFDC_02327	411469.EUBHAL_01869	2.2e-172	481.0	COG1434@1|root,COG1434@2|Bacteria,1VA42@1239|Firmicutes,24HKK@186801|Clostridia,25WW5@186806|Eubacteriaceae	186801|Clostridia	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
HLKFIFDC_02328	411469.EUBHAL_01870	1.4e-179	499.0	COG1409@1|root,COG1409@2|Bacteria,1V5YD@1239|Firmicutes,24J79@186801|Clostridia	186801|Clostridia	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
HLKFIFDC_02329	411469.EUBHAL_01871	3.19e-127	361.0	COG3177@1|root,COG3177@2|Bacteria,1TZWX@1239|Firmicutes,247MZ@186801|Clostridia,25WAR@186806|Eubacteriaceae	186801|Clostridia	M	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,HTH_26,HTH_3
HLKFIFDC_02330	411469.EUBHAL_01872	2.49e-82	244.0	COG1937@1|root,COG1937@2|Bacteria,1VEF5@1239|Firmicutes,24QRR@186801|Clostridia,25X0I@186806|Eubacteriaceae	186801|Clostridia	S	Metal-sensitive transcriptional repressor	csoR	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
HLKFIFDC_02331	411469.EUBHAL_01873	0.0	1552.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia,25UXY@186806|Eubacteriaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	actP	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
HLKFIFDC_02332	411469.EUBHAL_01874	0.0	1410.0	COG2340@1|root,COG3210@1|root,COG5263@1|root,COG2340@2|Bacteria,COG3210@2|Bacteria,COG5263@2|Bacteria	2|Bacteria	S	dextransucrase activity	ompC	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	CAP,CAP_assoc_N,SLH
HLKFIFDC_02333	411469.EUBHAL_01875	0.0	907.0	COG1649@1|root,COG1649@2|Bacteria,1TRTG@1239|Firmicutes,24B2F@186801|Clostridia,25W6I@186806|Eubacteriaceae	186801|Clostridia	S	lipoprotein YddW precursor K01189	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,GHL10,SLH
HLKFIFDC_02334	411469.EUBHAL_02910	2.59e-171	478.0	COG0037@1|root,COG0037@2|Bacteria,1TQ0Y@1239|Firmicutes,247RP@186801|Clostridia,25VQH@186806|Eubacteriaceae	186801|Clostridia	H	Belongs to the TtcA family	ttcA2	-	-	-	-	-	-	-	-	-	-	-	ATP_bind_3
HLKFIFDC_02335	411469.EUBHAL_02911	9.52e-249	683.0	COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,25C3N@186801|Clostridia,25V8U@186806|Eubacteriaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	xerS	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
HLKFIFDC_02336	411469.EUBHAL_02913	2.14e-143	405.0	COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,24AXJ@186801|Clostridia,25VX6@186806|Eubacteriaceae	186801|Clostridia	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
HLKFIFDC_02337	411469.EUBHAL_02912	6.29e-70	213.0	COG1388@1|root,COG1388@2|Bacteria,1VK16@1239|Firmicutes,24QWQ@186801|Clostridia,25XQ2@186806|Eubacteriaceae	186801|Clostridia	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
HLKFIFDC_02338	411469.EUBHAL_00220	5.68e-76	227.0	COG0799@1|root,COG0799@2|Bacteria,1VA2Z@1239|Firmicutes,24MVA@186801|Clostridia,25X65@186806|Eubacteriaceae	186801|Clostridia	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
HLKFIFDC_02339	411469.EUBHAL_00219	8.59e-133	376.0	COG1713@1|root,COG1713@2|Bacteria,1V6Y1@1239|Firmicutes,24HN2@186801|Clostridia,25WP2@186806|Eubacteriaceae	186801|Clostridia	H	Hydrolase, HD family	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like,HD
HLKFIFDC_02340	411469.EUBHAL_00218	1.84e-153	431.0	COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,24JFM@186801|Clostridia,25WQX@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
HLKFIFDC_02341	411469.EUBHAL_00217	2.3e-58	181.0	COG1534@1|root,COG1534@2|Bacteria,1VEGM@1239|Firmicutes,24QZB@186801|Clostridia,25WUD@186806|Eubacteriaceae	186801|Clostridia	J	RNA-binding protein containing KH domain, possibly ribosomal protein	yhbY	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
HLKFIFDC_02342	411469.EUBHAL_00216	1.81e-309	843.0	COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,247SP@186801|Clostridia,25UQD@186806|Eubacteriaceae	186801|Clostridia	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
HLKFIFDC_02343	411469.EUBHAL_00215	6.15e-62	189.0	COG0211@1|root,COG0211@2|Bacteria,1V6HW@1239|Firmicutes,24N3D@186801|Clostridia,25WK4@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
HLKFIFDC_02344	411469.EUBHAL_00214	4.5e-71	214.0	COG2868@1|root,COG2868@2|Bacteria,1VCNG@1239|Firmicutes,24R3H@186801|Clostridia,25XCB@186806|Eubacteriaceae	186801|Clostridia	J	Cysteine protease Prp	-	-	-	ko:K07584	-	-	-	-	ko00000	-	-	-	Peptidase_Prp
HLKFIFDC_02345	411469.EUBHAL_00213	3.67e-65	198.0	COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,24MRS@186801|Clostridia,25WX1@186806|Eubacteriaceae	186801|Clostridia	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
HLKFIFDC_02346	411469.EUBHAL_00212	4.06e-286	782.0	COG1530@1|root,COG1530@2|Bacteria,1TQS4@1239|Firmicutes,247QV@186801|Clostridia,25VTU@186806|Eubacteriaceae	186801|Clostridia	J	ribonuclease, Rne Rng family	rng	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1,TRAM
HLKFIFDC_02347	411469.EUBHAL_00211	9.01e-147	414.0	COG3584@1|root,COG5492@1|root,COG3584@2|Bacteria,COG5492@2|Bacteria,1VGG7@1239|Firmicutes,25NR6@186801|Clostridia,25XCK@186806|Eubacteriaceae	186801|Clostridia	N	3D domain	-	-	-	-	-	-	-	-	-	-	-	-	3D
HLKFIFDC_02348	411469.EUBHAL_00210	2.31e-180	502.0	COG5011@1|root,COG5011@2|Bacteria,1V4D0@1239|Firmicutes,249GU@186801|Clostridia,25WF4@186806|Eubacteriaceae	186801|Clostridia	S	Radical SAM-linked protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344
HLKFIFDC_02349	411469.EUBHAL_00209	0.0	1259.0	COG1032@1|root,COG1032@2|Bacteria,1TR2C@1239|Firmicutes,248HM@186801|Clostridia,25VMX@186806|Eubacteriaceae	186801|Clostridia	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
HLKFIFDC_02350	515620.EUBELI_20209	1.91e-100	294.0	28NU7@1|root,2ZBSM@2|Bacteria,1V2N8@1239|Firmicutes,24G4F@186801|Clostridia,25VQU@186806|Eubacteriaceae	186801|Clostridia	S	NOG32933 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02351	1256908.HMPREF0373_01457	0.0	1016.0	COG2199@1|root,COG3452@1|root,COG2199@2|Bacteria,COG3452@2|Bacteria,1TRCK@1239|Firmicutes,24A7A@186801|Clostridia,25XIB@186806|Eubacteriaceae	186801|Clostridia	T	CHASE	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GGDEF,PAS_3,dCache_1
HLKFIFDC_02352	411469.EUBHAL_00194	4.97e-227	625.0	COG0521@1|root,COG2258@1|root,COG0521@2|Bacteria,COG2258@2|Bacteria,1V3XM@1239|Firmicutes,24HG2@186801|Clostridia,25WK8@186806|Eubacteriaceae	186801|Clostridia	H	Probable molybdopterin binding domain	mog	-	-	-	-	-	-	-	-	-	-	-	MOSC,MoCF_biosynth
HLKFIFDC_02353	411469.EUBHAL_00193	1.7e-145	410.0	COG1309@1|root,COG1309@2|Bacteria,1V27T@1239|Firmicutes,24G6P@186801|Clostridia,25XV2@186806|Eubacteriaceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HLKFIFDC_02354	411469.EUBHAL_00192	1.22e-215	596.0	COG2896@1|root,COG2896@2|Bacteria,1TP89@1239|Firmicutes,247PP@186801|Clostridia,25WDY@186806|Eubacteriaceae	186801|Clostridia	H	Molybdenum cofactor biosynthesis protein A	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
HLKFIFDC_02355	411469.EUBHAL_00191	0.0	890.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,25URT@186806|Eubacteriaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HLKFIFDC_02356	411469.EUBHAL_00190	9.04e-78	231.0	COG0347@1|root,COG0347@2|Bacteria,1V9Z5@1239|Firmicutes,24MNA@186801|Clostridia,25X0F@186806|Eubacteriaceae	186801|Clostridia	K	Nitrogen regulatory protein P-II	glnB	-	-	ko:K04751,ko:K04752	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
HLKFIFDC_02357	411469.EUBHAL_00189	1.63e-297	811.0	COG0004@1|root,COG0004@2|Bacteria,1TQYG@1239|Firmicutes,247W1@186801|Clostridia,25V1P@186806|Eubacteriaceae	186801|Clostridia	P	Ammonium Transporter Family	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
HLKFIFDC_02358	411469.EUBHAL_00188	4.06e-93	271.0	COG1433@1|root,COG1433@2|Bacteria,1V7KS@1239|Firmicutes,24MUB@186801|Clostridia,25X0S@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
HLKFIFDC_02360	411469.EUBHAL_00186	1.58e-95	279.0	2BVD7@1|root,32QT8@2|Bacteria,1V6S8@1239|Firmicutes,257S3@186801|Clostridia,25YU5@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02361	411469.EUBHAL_00184	2.81e-178	496.0	COG3279@1|root,COG3279@2|Bacteria,1V0X7@1239|Firmicutes,24EP3@186801|Clostridia,25XIK@186806|Eubacteriaceae	186801|Clostridia	K	Cytoplasmic, score 8.87	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
HLKFIFDC_02362	411469.EUBHAL_00183	7.71e-190	528.0	COG3290@1|root,COG3290@2|Bacteria,1UVHJ@1239|Firmicutes,25KIG@186801|Clostridia,25Z9S@186806|Eubacteriaceae	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
HLKFIFDC_02364	411469.EUBHAL_00181	1.07e-107	310.0	COG0494@1|root,COG0494@2|Bacteria,1UJC7@1239|Firmicutes,25F1K@186801|Clostridia,25W1S@186806|Eubacteriaceae	186801|Clostridia	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
HLKFIFDC_02366	411469.EUBHAL_00179	0.0	1022.0	COG0768@1|root,COG0768@2|Bacteria,1TPER@1239|Firmicutes,2486R@186801|Clostridia,25VFC@186806|Eubacteriaceae	186801|Clostridia	M	Penicillin-binding protein, transpeptidase domain protein	pbpA2	-	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
HLKFIFDC_02367	411469.EUBHAL_00178	4.32e-306	836.0	COG0772@1|root,COG0772@2|Bacteria,1TQ82@1239|Firmicutes,248QS@186801|Clostridia,25VQZ@186806|Eubacteriaceae	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FHA,FTSW_RODA_SPOVE
HLKFIFDC_02368	411469.EUBHAL_00177	0.0	1677.0	COG0826@1|root,COG0826@2|Bacteria,1TQS1@1239|Firmicutes,24909@186801|Clostridia,25UZK@186806|Eubacteriaceae	186801|Clostridia	O	Peptidase, U32 family	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
HLKFIFDC_02369	411469.EUBHAL_00176	1e-83	248.0	COG3027@1|root,COG3027@2|Bacteria,1V4E5@1239|Firmicutes,24HQR@186801|Clostridia,25XHG@186806|Eubacteriaceae	186801|Clostridia	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
HLKFIFDC_02370	411469.EUBHAL_00175	9.8e-234	644.0	COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,247W0@186801|Clostridia,25VC7@186806|Eubacteriaceae	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
HLKFIFDC_02371	411469.EUBHAL_00174	7.03e-150	423.0	COG0632@1|root,COG0632@2|Bacteria,1V3KF@1239|Firmicutes,24JKV@186801|Clostridia,25W9F@186806|Eubacteriaceae	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
HLKFIFDC_02372	411469.EUBHAL_00173	6.17e-284	775.0	COG3359@1|root,COG3359@2|Bacteria,1U725@1239|Firmicutes,24A9V@186801|Clostridia,25WE0@186806|Eubacteriaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
HLKFIFDC_02373	411469.EUBHAL_00172	2.32e-280	766.0	COG0426@1|root,COG0426@2|Bacteria,1TQE9@1239|Firmicutes,249CU@186801|Clostridia,25V9U@186806|Eubacteriaceae	186801|Clostridia	C	Metallo-beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct,Flavodoxin_5,Lactamase_B
HLKFIFDC_02374	411469.EUBHAL_00171	0.0	1120.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,25URG@186806|Eubacteriaceae	186801|Clostridia	V	ABC-type multidrug transport system, ATPase and permease	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HLKFIFDC_02375	411469.EUBHAL_00170	0.0	1078.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia,25V5W@186806|Eubacteriaceae	186801|Clostridia	V	ABC-type multidrug transport system, ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HLKFIFDC_02376	411469.EUBHAL_00169	3.52e-79	236.0	COG1321@1|root,COG1321@2|Bacteria,1V3IS@1239|Firmicutes,24MSE@186801|Clostridia,25WVQ@186806|Eubacteriaceae	186801|Clostridia	K	Iron dependent repressor DNA binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fe_dep_repr_C,Fe_dep_repress
HLKFIFDC_02377	411469.EUBHAL_00168	0.0	1108.0	COG2200@1|root,COG2200@2|Bacteria,1TS8B@1239|Firmicutes,24EZ4@186801|Clostridia,25ZU9@186806|Eubacteriaceae	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_9
HLKFIFDC_02378	411469.EUBHAL_00167	1.33e-245	676.0	COG3480@1|root,COG3480@2|Bacteria,1UI0S@1239|Firmicutes,25E9E@186801|Clostridia,25W6F@186806|Eubacteriaceae	186801|Clostridia	T	Stage IV sporulation protein B	spoIVB	-	3.4.21.116	ko:K06399	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S55
HLKFIFDC_02379	411469.EUBHAL_00166	0.0	1033.0	COG0497@1|root,COG0497@2|Bacteria,1TP99@1239|Firmicutes,247KB@186801|Clostridia,25VF8@186806|Eubacteriaceae	186801|Clostridia	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
HLKFIFDC_02380	411469.EUBHAL_00165	3.72e-100	291.0	COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,24HGQ@186801|Clostridia,25WB7@186806|Eubacteriaceae	186801|Clostridia	K	Regulates arginine biosynthesis genes	argR	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
HLKFIFDC_02381	411469.EUBHAL_00164	5.86e-191	531.0	COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,24BG6@186801|Clostridia,25WA9@186806|Eubacteriaceae	186801|Clostridia	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS05480	NAD_kinase
HLKFIFDC_02382	411469.EUBHAL_00163	4.49e-193	536.0	COG1189@1|root,COG1189@2|Bacteria,1TPE4@1239|Firmicutes,247VH@186801|Clostridia,25VEW@186806|Eubacteriaceae	186801|Clostridia	J	Ribosomal RNA large subunit methyltransferase J	rrmJ	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
HLKFIFDC_02383	411469.EUBHAL_00162	0.0	1227.0	COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,247P1@186801|Clostridia,25UUI@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
HLKFIFDC_02384	411469.EUBHAL_00161	6.9e-202	560.0	COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,248DE@186801|Clostridia,25VS6@186806|Eubacteriaceae	186801|Clostridia	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	iHN637.CLJU_RS05465	polyprenyl_synt
HLKFIFDC_02385	553973.CLOHYLEM_06735	2.19e-06	48.1	COG1722@1|root,COG1722@2|Bacteria,1VK9I@1239|Firmicutes,24UH5@186801|Clostridia,221F7@1506553|Lachnoclostridium	186801|Clostridia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
HLKFIFDC_02386	411469.EUBHAL_00159	1.94e-288	788.0	COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,247KE@186801|Clostridia,25V6S@186806|Eubacteriaceae	186801|Clostridia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
HLKFIFDC_02387	411469.EUBHAL_00158	3.35e-87	256.0	COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,24MQ3@186801|Clostridia,25XA6@186806|Eubacteriaceae	186801|Clostridia	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
HLKFIFDC_02388	411469.EUBHAL_00157	1.39e-79	237.0	COG1302@1|root,COG1302@2|Bacteria,1V4IC@1239|Firmicutes,24JNM@186801|Clostridia,25WSH@186806|Eubacteriaceae	186801|Clostridia	S	Asp23 family, cell envelope-related function	asp	-	-	-	-	-	-	-	-	-	-	-	Asp23
HLKFIFDC_02389	411469.EUBHAL_00155	4.37e-124	357.0	2E3US@1|root,32YS3@2|Bacteria,1VESK@1239|Firmicutes,24R9H@186801|Clostridia,25W2P@186806|Eubacteriaceae	186801|Clostridia	S	non supervised orthologous group	spoIIIAH	-	-	ko:K06397	-	-	-	-	ko00000	1.A.34.1.1	-	-	SpoIIIAH
HLKFIFDC_02390	411469.EUBHAL_00154	5.86e-116	334.0	2E6BB@1|root,330Z5@2|Bacteria,1VF3M@1239|Firmicutes,24RAX@186801|Clostridia,25WYD@186806|Eubacteriaceae	186801|Clostridia	S	stage III sporulation protein AG	spoIIIAG	-	-	ko:K06396	-	-	-	-	ko00000	-	-	-	-
HLKFIFDC_02392	411469.EUBHAL_00152	1.59e-249	687.0	2C2CG@1|root,2Z7PW@2|Bacteria,1TQQ2@1239|Firmicutes,24AH2@186801|Clostridia,25W9Y@186806|Eubacteriaceae	186801|Clostridia	S	stage III sporulation protein AE	spoIIIAE	-	-	ko:K06394	-	-	-	-	ko00000	-	-	-	Spore_III_AE
HLKFIFDC_02393	411469.EUBHAL_00151	3.14e-76	228.0	2CPUI@1|root,32SJW@2|Bacteria,1VA9Y@1239|Firmicutes,24NK6@186801|Clostridia,25XB1@186806|Eubacteriaceae	186801|Clostridia	S	Stage III sporulation protein AC/AD protein family	spoIIIAD	-	-	ko:K06393	-	-	-	-	ko00000	-	-	-	SpoIIIAC
HLKFIFDC_02394	411469.EUBHAL_00150	5.86e-39	130.0	2E555@1|root,32ZY3@2|Bacteria,1VEM4@1239|Firmicutes,24QNR@186801|Clostridia,25X7M@186806|Eubacteriaceae	186801|Clostridia	S	Stage III sporulation protein AC	spoIIIAC	-	-	ko:K06392	-	-	-	-	ko00000	-	-	-	SpoIIIAC
HLKFIFDC_02397	411469.EUBHAL_00147	2.13e-230	634.0	COG3854@1|root,COG3854@2|Bacteria,1TQ23@1239|Firmicutes,248S2@186801|Clostridia,25W44@186806|Eubacteriaceae	186801|Clostridia	S	stage III sporulation protein AA	spoIIIAA	-	-	ko:K06390	-	-	-	-	ko00000	-	-	-	T2SSE
HLKFIFDC_02398	411469.EUBHAL_00146	4.87e-286	783.0	COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,248D5@186801|Clostridia,25UV8@186806|Eubacteriaceae	186801|Clostridia	E	Threonine dehydratase	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PALP
HLKFIFDC_02399	411469.EUBHAL_00145	1.08e-215	596.0	COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,247JD@186801|Clostridia,25USB@186806|Eubacteriaceae	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
HLKFIFDC_02400	411469.EUBHAL_00144	0.0	1682.0	COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,249F4@186801|Clostridia,25V6U@186806|Eubacteriaceae	186801|Clostridia	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
HLKFIFDC_02401	411469.EUBHAL_00143	9.02e-163	456.0	COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,249QD@186801|Clostridia,25UYS@186806|Eubacteriaceae	186801|Clostridia	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
HLKFIFDC_02402	411469.EUBHAL_00142	2.98e-238	657.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia,25VAU@186806|Eubacteriaceae	186801|Clostridia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
HLKFIFDC_02403	1347392.CCEZ01000049_gene1357	1e-20	97.1	COG0407@1|root,COG0407@2|Bacteria,1TSUR@1239|Firmicutes,24ARM@186801|Clostridia,36FQD@31979|Clostridiaceae	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
HLKFIFDC_02412	411469.EUBHAL_03118	3.14e-127	362.0	COG1838@1|root,COG1838@2|Bacteria,1V1CP@1239|Firmicutes,24FRK@186801|Clostridia,25W16@186806|Eubacteriaceae	186801|Clostridia	C	Hydrolyase, tartrate beta subunit fumarate domain protein, Fe-S type	fumB	-	4.2.1.2	ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
HLKFIFDC_02413	411469.EUBHAL_03119	5.94e-201	556.0	COG1951@1|root,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,248T7@186801|Clostridia,25VS3@186806|Eubacteriaceae	186801|Clostridia	C	Hydrolyase, tartrate alpha subunit fumarate domain protein, Fe-S type	fumA	-	4.2.1.2,4.2.1.32	ko:K01677,ko:K03779	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00339,R01082	RC00443,RC01382	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
HLKFIFDC_02414	411469.EUBHAL_03120	0.0	1544.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,2482G@186801|Clostridia,25UZ0@186806|Eubacteriaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
HLKFIFDC_02415	411469.EUBHAL_03121	0.0	1268.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,248AV@186801|Clostridia,25VFV@186806|Eubacteriaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
HLKFIFDC_02416	411469.EUBHAL_03122	2.06e-258	709.0	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,247KY@186801|Clostridia,25V7R@186806|Eubacteriaceae	186801|Clostridia	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
HLKFIFDC_02417	411469.EUBHAL_03123	7.4e-41	134.0	COG2501@1|root,COG2501@2|Bacteria,1VYQT@1239|Firmicutes,24QZU@186801|Clostridia,25XAF@186806|Eubacteriaceae	186801|Clostridia	S	S4 domain	yaaA	-	-	ko:K14761	-	-	-	-	ko00000,ko03009	-	-	-	S4_2
HLKFIFDC_02418	411469.EUBHAL_03124	2.07e-260	714.0	COG0592@1|root,COG0592@2|Bacteria,1TQ7J@1239|Firmicutes,248EG@186801|Clostridia,25UUV@186806|Eubacteriaceae	186801|Clostridia	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
HLKFIFDC_02419	411469.EUBHAL_03125	0.0	876.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,2490S@186801|Clostridia,25UYE@186806|Eubacteriaceae	186801|Clostridia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
HLKFIFDC_02420	411469.EUBHAL_03126	7.96e-21	82.4	COG0230@1|root,COG0230@2|Bacteria,1VK90@1239|Firmicutes,24UGN@186801|Clostridia,25XP8@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
HLKFIFDC_02421	411469.EUBHAL_03127	6.41e-77	229.0	COG0594@1|root,COG0594@2|Bacteria,1VA78@1239|Firmicutes,24QK5@186801|Clostridia,25X1N@186806|Eubacteriaceae	186801|Clostridia	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
HLKFIFDC_02422	411469.EUBHAL_03128	2.09e-45	146.0	COG0759@1|root,COG0759@2|Bacteria,1VEIG@1239|Firmicutes,24QN4@186801|Clostridia,25XH9@186806|Eubacteriaceae	186801|Clostridia	S	Could be involved in insertion of integral membrane proteins into the membrane	yidD	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
HLKFIFDC_02423	411469.EUBHAL_03129	1.35e-299	818.0	COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,247V9@186801|Clostridia,25VNJ@186806|Eubacteriaceae	186801|Clostridia	U	Membrane protein insertase, YidC Oxa1 family	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
HLKFIFDC_02424	411469.EUBHAL_03130	2.14e-141	400.0	COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,249EA@186801|Clostridia,25UVE@186806|Eubacteriaceae	186801|Clostridia	S	R3H domain protein	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
HLKFIFDC_02425	411469.EUBHAL_03131	0.0	887.0	COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,248A9@186801|Clostridia,25URZ@186806|Eubacteriaceae	186801|Clostridia	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
HLKFIFDC_02426	411469.EUBHAL_03132	0.0	1222.0	COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,247U2@186801|Clostridia,25UR2@186806|Eubacteriaceae	186801|Clostridia	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
HLKFIFDC_02427	411469.EUBHAL_03133	1.62e-168	471.0	COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,247WM@186801|Clostridia,25W3T@186806|Eubacteriaceae	186801|Clostridia	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
HLKFIFDC_02429	411469.EUBHAL_03135	0.0	1133.0	COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,248JZ@186801|Clostridia,25VGI@186806|Eubacteriaceae	186801|Clostridia	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
HLKFIFDC_02430	411469.EUBHAL_02624	6.57e-177	493.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,2488C@186801|Clostridia,25URC@186806|Eubacteriaceae	186801|Clostridia	D	CobQ CobB MinD ParA nucleotide binding domain	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
HLKFIFDC_02431	411469.EUBHAL_02623	1.57e-202	563.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,249VV@186801|Clostridia,25UXZ@186806|Eubacteriaceae	186801|Clostridia	K	Belongs to the ParB family	spo0J	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
HLKFIFDC_02432	411469.EUBHAL_02622	8.99e-116	332.0	COG1196@1|root,COG1196@2|Bacteria,1VAV4@1239|Firmicutes,24NPU@186801|Clostridia,25WKE@186806|Eubacteriaceae	186801|Clostridia	D	Protein of unknown function (DUF4446)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4446
HLKFIFDC_02433	411469.EUBHAL_02621	2.85e-209	578.0	28J5A@1|root,2Z916@2|Bacteria,1TSGX@1239|Firmicutes,24AZU@186801|Clostridia,25VBZ@186806|Eubacteriaceae	186801|Clostridia	S	Domain of unknown function, E. rectale Gene description (DUF3881)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3881
HLKFIFDC_02435	500632.CLONEX_02363	4.53e-199	553.0	COG1475@1|root,COG1475@2|Bacteria,1TR7C@1239|Firmicutes,247TW@186801|Clostridia	186801|Clostridia	K	Belongs to the ParB family	-	-	-	-	-	-	-	-	-	-	-	-	ParBc
HLKFIFDC_02436	1121115.AXVN01000113_gene2375	1.54e-174	488.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,247R1@186801|Clostridia,3XZBU@572511|Blautia	186801|Clostridia	D	CobQ CobB MinD ParA nucleotide binding domain protein	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
HLKFIFDC_02437	1121115.AXVN01000113_gene2374	9.11e-191	532.0	COG1475@1|root,COG1475@2|Bacteria,1TR7C@1239|Firmicutes,247TW@186801|Clostridia,3XYKZ@572511|Blautia	186801|Clostridia	K	ParB-like nuclease domain	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
HLKFIFDC_02438	411461.DORFOR_02721	9.13e-238	654.0	2DBC6@1|root,2Z8BZ@2|Bacteria,1TQXM@1239|Firmicutes,2484N@186801|Clostridia,27W7P@189330|Dorea	186801|Clostridia	S	COG NOG34358 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	RepA_N
HLKFIFDC_02439	411461.DORFOR_02720	4.57e-55	172.0	2C39Y@1|root,32RBW@2|Bacteria,1V801@1239|Firmicutes,24JSG@186801|Clostridia,27WV7@189330|Dorea	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02440	411461.DORFOR_02719	2.08e-90	265.0	28PX5@1|root,2ZCH7@2|Bacteria,1V32H@1239|Firmicutes,24GGF@186801|Clostridia,27WRI@189330|Dorea	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02441	411467.BACCAP_02982	9.42e-108	309.0	COG3631@1|root,COG3631@2|Bacteria,1V76Z@1239|Firmicutes,24MNK@186801|Clostridia,2692T@186813|unclassified Clostridiales	186801|Clostridia	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
HLKFIFDC_02442	411461.DORFOR_02716	4.49e-159	446.0	COG0745@1|root,COG0745@2|Bacteria,1TQ0D@1239|Firmicutes,248WX@186801|Clostridia	186801|Clostridia	KT	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K20488	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HLKFIFDC_02443	411461.DORFOR_02715	2.38e-273	749.0	COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,1TRZX@1239|Firmicutes,249AI@186801|Clostridia,27W6U@189330|Dorea	186801|Clostridia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
HLKFIFDC_02444	411461.DORFOR_02714	1.4e-248	683.0	COG1277@1|root,COG1277@2|Bacteria,1UYRU@1239|Firmicutes,24A07@186801|Clostridia,27WQ5@189330|Dorea	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
HLKFIFDC_02445	411461.DORFOR_02713	1.18e-147	416.0	2B7SS@1|root,320Z4@2|Bacteria,1V805@1239|Firmicutes,24IU3@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02446	411461.DORFOR_02712	1.58e-206	571.0	COG1131@1|root,COG1131@2|Bacteria,1TRJH@1239|Firmicutes,247XQ@186801|Clostridia,27WF2@189330|Dorea	186801|Clostridia	V	COG COG1131 ABC-type multidrug transport system, ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
HLKFIFDC_02447	411461.DORFOR_02710	5.28e-23	89.7	2C9RV@1|root,32TR5@2|Bacteria,1VDVS@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02448	411461.DORFOR_02709	1.02e-156	439.0	2DMUC@1|root,32TQR@2|Bacteria,1V9Y3@1239|Firmicutes,24QZE@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	CpXC
HLKFIFDC_02449	411461.DORFOR_02708	6.37e-120	342.0	COG2856@1|root,COG2856@2|Bacteria,1V1KH@1239|Firmicutes,24GHH@186801|Clostridia,27WZE@189330|Dorea	186801|Clostridia	E	Pfam:DUF955	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
HLKFIFDC_02450	411459.RUMOBE_02098	3.45e-88	260.0	COG1476@1|root,COG1476@2|Bacteria,1VAJB@1239|Firmicutes,24N2Z@186801|Clostridia,3Y1IE@572511|Blautia	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
HLKFIFDC_02451	411461.DORFOR_02706	3.64e-314	855.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,248FH@186801|Clostridia,27WI2@189330|Dorea	186801|Clostridia	L	impB/mucB/samB family	-	-	-	ko:K03502	-	-	-	-	ko00000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
HLKFIFDC_02452	411459.RUMOBE_02100	5.9e-78	232.0	2CD9B@1|root,2ZC0J@2|Bacteria,1V2HS@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02453	411459.RUMOBE_02101	2.98e-48	154.0	2E0R5@1|root,32W9G@2|Bacteria,1VE1B@1239|Firmicutes,24PQS@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02454	411461.DORFOR_02702	2.35e-17	73.6	2924K@1|root,2ZPPK@2|Bacteria,1W5V4@1239|Firmicutes,256EY@186801|Clostridia	186801|Clostridia	S	Psort location Extracellular, score 7.50	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02455	411459.RUMOBE_02104	2.69e-136	387.0	COG1595@1|root,COG1595@2|Bacteria,1TQ1Q@1239|Firmicutes,25JVV@186801|Clostridia,3Y1NW@572511|Blautia	186801|Clostridia	K	Putative helix-turn-helix protein, YlxM / p13 like	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02456	411461.DORFOR_02699	0.0	3325.0	COG4932@1|root,COG4932@2|Bacteria,1TRG6@1239|Firmicutes,2492K@186801|Clostridia,27V8U@189330|Dorea	186801|Clostridia	M	Cna protein B-type domain	-	-	-	-	-	-	-	-	-	-	-	-	Gram_pos_anchor
HLKFIFDC_02457	411459.RUMOBE_02107	2.14e-20	81.6	2ECWX@1|root,336U4@2|Bacteria,1VGNU@1239|Firmicutes,252ZY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02458	411459.RUMOBE_02108	3.28e-70	210.0	2AESW@1|root,314PS@2|Bacteria,1V7GZ@1239|Firmicutes,24S9C@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02459	518637.EUBIFOR_00804	6.9e-97	285.0	28I1B@1|root,2Z93C@2|Bacteria,1UIR3@1239|Firmicutes,3VQT2@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Protein of unknown function (DUF3801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3801
HLKFIFDC_02460	411459.RUMOBE_02110	0.0	1185.0	COG3505@1|root,COG3505@2|Bacteria,1TPCF@1239|Firmicutes,2489C@186801|Clostridia,3XYP3@572511|Blautia	186801|Clostridia	U	COG COG3505 Type IV secretory pathway, VirD4 components	-	-	-	ko:K03205	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	T4SS-DNA_transf,TraG-D_C
HLKFIFDC_02461	411459.RUMOBE_02111	8.52e-41	134.0	2CDEH@1|root,32RXK@2|Bacteria,1VA17@1239|Firmicutes,24MPR@186801|Clostridia,3Y0UR@572511|Blautia	186801|Clostridia	S	Maff2 family	-	-	-	-	-	-	-	-	-	-	-	-	Maff2
HLKFIFDC_02462	411459.RUMOBE_02112	1.96e-195	543.0	28HUM@1|root,2Z81B@2|Bacteria,1TNZ2@1239|Firmicutes,248SU@186801|Clostridia,3XYX7@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02463	411459.RUMOBE_02113	2.21e-81	241.0	COG3451@1|root,COG3451@2|Bacteria,1V74G@1239|Firmicutes,24GFI@186801|Clostridia,3Y0CF@572511|Blautia	186801|Clostridia	U	PrgI family protein	-	-	-	-	-	-	-	-	-	-	-	-	PrgI
HLKFIFDC_02464	411461.DORFOR_02689	0.0	1542.0	COG3451@1|root,COG3451@2|Bacteria,1TPDR@1239|Firmicutes,248ND@186801|Clostridia	186801|Clostridia	U	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10
HLKFIFDC_02465	411461.DORFOR_02688	4.89e-114	326.0	2DBSF@1|root,2ZARZ@2|Bacteria,1TR8R@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	YozE_SAM_like
HLKFIFDC_02466	411461.DORFOR_02687	0.0	1439.0	COG0791@1|root,COG3064@1|root,COG3584@1|root,COG0791@2|Bacteria,COG3064@2|Bacteria,COG3584@2|Bacteria,1TP24@1239|Firmicutes,247K5@186801|Clostridia,27WB3@189330|Dorea	186801|Clostridia	M	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
HLKFIFDC_02467	411461.DORFOR_02686	2.91e-62	191.0	2DMK1@1|root,32S39@2|Bacteria,1VADK@1239|Firmicutes	1239|Firmicutes	S	Domain of unknown function (DUF4315)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4315
HLKFIFDC_02468	411461.DORFOR_02685	1.57e-153	433.0	COG2433@1|root,COG2433@2|Bacteria,1UVG6@1239|Firmicutes,24TWC@186801|Clostridia,27WQI@189330|Dorea	186801|Clostridia	S	Domain of unknown function (DUF4366)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4366
HLKFIFDC_02469	411461.DORFOR_02684	0.0	1380.0	COG0550@1|root,COG0550@2|Bacteria,1TPJD@1239|Firmicutes,24XJJ@186801|Clostridia	186801|Clostridia	L	Bacterial DNA topoisomerase I DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Topoisom_bac,Toprim
HLKFIFDC_02470	411461.DORFOR_02683	3.06e-240	661.0	28PM6@1|root,2Z8J4@2|Bacteria,1UXZE@1239|Firmicutes,25MCD@186801|Clostridia,27VPH@189330|Dorea	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02471	411459.RUMOBE_02121	1.89e-28	102.0	2C2RI@1|root,344Z0@2|Bacteria,1W0Y1@1239|Firmicutes,253WR@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02472	411461.DORFOR_02681	0.0	1675.0	COG2003@1|root,COG4227@1|root,COG2003@2|Bacteria,COG4227@2|Bacteria,1TQN4@1239|Firmicutes,2482H@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1738,DUF4316,Peptidase_M78,RadC,YodL
HLKFIFDC_02473	411459.RUMOBE_02127	7.28e-51	161.0	2C2HG@1|root,32RAG@2|Bacteria,1V8H6@1239|Firmicutes,252A1@186801|Clostridia,3Y0M3@572511|Blautia	186801|Clostridia	S	Putative tranposon-transfer assisting protein	-	-	-	-	-	-	-	-	-	-	-	-	TTRAP
HLKFIFDC_02474	411459.RUMOBE_02128	2.79e-197	548.0	28MJQ@1|root,2ZAW4@2|Bacteria,1UF72@1239|Firmicutes,24YQA@186801|Clostridia,3XZNI@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF4316)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4316,YodL
HLKFIFDC_02475	1235798.C817_05092	3.82e-83	253.0	COG3279@1|root,COG3279@2|Bacteria,1UYV2@1239|Firmicutes,24F5U@186801|Clostridia	186801|Clostridia	KT	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
HLKFIFDC_02476	1235798.C817_05094	5.25e-84	268.0	COG3290@1|root,COG3290@2|Bacteria,1V2Z1@1239|Firmicutes,24GVB@186801|Clostridia	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
HLKFIFDC_02477	1069533.Sinf_0929	5.42e-40	142.0	COG1131@1|root,COG1131@2|Bacteria,1V3UQ@1239|Firmicutes,4HIDP@91061|Bacilli	91061|Bacilli	V	abc transporter atp-binding protein	-	-	-	ko:K16917	ko02010,map02010	M00583	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.133.1	-	-	ABC_tran
HLKFIFDC_02478	1499689.CCNN01000006_gene529	2.64e-62	201.0	2BK2W@1|root,32EG8@2|Bacteria,1U0KW@1239|Firmicutes,253E5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02479	478749.BRYFOR_08936	8.51e-24	96.7	COG0745@1|root,COG0745@2|Bacteria,1VH87@1239|Firmicutes,24KDC@186801|Clostridia	186801|Clostridia	KT	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
HLKFIFDC_02480	518637.EUBIFOR_00742	2.84e-44	145.0	2DE2W@1|root,2ZKAM@2|Bacteria,1V3EH@1239|Firmicutes,3VTHV@526524|Erysipelotrichia	526524|Erysipelotrichia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02481	411459.RUMOBE_02142	3.19e-59	182.0	COG1396@1|root,COG1396@2|Bacteria,1V921@1239|Firmicutes,250UR@186801|Clostridia	186801|Clostridia	K	Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HLKFIFDC_02482	411461.DORFOR_02674	2.81e-74	222.0	COG0756@1|root,COG0756@2|Bacteria,1VGM6@1239|Firmicutes,24G06@186801|Clostridia,27VWJ@189330|Dorea	186801|Clostridia	F	dUTPase	-	-	-	-	-	-	-	-	-	-	-	-	dUTPase
HLKFIFDC_02483	518637.EUBIFOR_00739	5.9e-186	516.0	COG1351@1|root,COG1351@2|Bacteria	2|Bacteria	F	thymidylate synthase (FAD) activity	-	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
HLKFIFDC_02484	411461.DORFOR_02672	2.81e-74	222.0	2A2ID@1|root,30QVY@2|Bacteria,1V4BJ@1239|Firmicutes,25E0Y@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02485	658088.HMPREF0987_02297	0.0	941.0	COG1196@1|root,COG1196@2|Bacteria,1UHVD@1239|Firmicutes,25E44@186801|Clostridia,27UCV@186928|unclassified Lachnospiraceae	186801|Clostridia	D	COG COG3843 Type IV secretory pathway, VirD2 components (relaxase)	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
HLKFIFDC_02486	518637.EUBIFOR_00736	1.34e-86	254.0	2C2YH@1|root,2ZBKZ@2|Bacteria,1V3N8@1239|Firmicutes,3VTF7@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	MobC
HLKFIFDC_02487	742765.HMPREF9457_03295	1.1e-98	286.0	COG0454@1|root,COG0456@2|Bacteria,1VAFS@1239|Firmicutes,24MUI@186801|Clostridia,27VXG@189330|Dorea	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	ko:K03826	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_10,Acetyltransf_7
HLKFIFDC_02488	1121115.AXVN01000065_gene680	8.86e-35	119.0	2CHQ1@1|root,3240C@2|Bacteria,1UQE2@1239|Firmicutes,25855@186801|Clostridia,3Y1Z3@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02489	665950.HMPREF1025_00894	1.43e-73	220.0	2C9NK@1|root,32RPI@2|Bacteria,1V7S6@1239|Firmicutes,25CVV@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF3784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3784
HLKFIFDC_02491	742765.HMPREF9457_00664	1.95e-85	252.0	2DRY9@1|root,33DNC@2|Bacteria,1V1G6@1239|Firmicutes,24GGT@186801|Clostridia,27WZD@189330|Dorea	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02492	742765.HMPREF9457_03230	5.87e-62	191.0	295RU@1|root,2ZT35@2|Bacteria,1V63F@1239|Firmicutes,24TPB@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF3784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3784
HLKFIFDC_02493	1410624.JNKK01000001_gene670	1.38e-163	464.0	COG3547@1|root,COG3547@2|Bacteria,1TPSP@1239|Firmicutes,24AH4@186801|Clostridia,27TFA@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
HLKFIFDC_02494	1123314.AUIO01000002_gene1893	2.96e-88	258.0	2C5R4@1|root,2ZC1N@2|Bacteria,1V292@1239|Firmicutes	1239|Firmicutes	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
HLKFIFDC_02495	1154860.SAG0136_11695	0.0	1274.0	COG0480@1|root,COG0480@2|Bacteria,1TPQH@1239|Firmicutes,4HAS9@91061|Bacilli	91061|Bacilli	J	elongation factor G	tetM	-	-	ko:K18220	-	-	-	-	br01600,ko00000,ko01504	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
HLKFIFDC_02496	411461.DORFOR_02101	5.09e-238	654.0	COG0820@1|root,COG0820@2|Bacteria,1TPVF@1239|Firmicutes,248BC@186801|Clostridia,27V1T@189330|Dorea	186801|Clostridia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	-	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
HLKFIFDC_02497	411461.DORFOR_02102	3.57e-39	129.0	2DP5Q@1|root,330MY@2|Bacteria,1VFAQ@1239|Firmicutes,24R7E@186801|Clostridia,27VWT@189330|Dorea	186801|Clostridia	S	Cysteine-rich KTR	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_KTR
HLKFIFDC_02498	861454.HMPREF9099_02776	3.64e-68	207.0	COG1396@1|root,COG1396@2|Bacteria,1V58U@1239|Firmicutes,24HKI@186801|Clostridia,27N4I@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HLKFIFDC_02499	518637.EUBIFOR_00728	3.11e-35	119.0	COG3311@1|root,COG3311@2|Bacteria,1V8AE@1239|Firmicutes,3VU5J@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
HLKFIFDC_02500	518637.EUBIFOR_00727	1.75e-229	632.0	29YMG@1|root,30KGY@2|Bacteria,1V4T3@1239|Firmicutes,3VR5D@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
HLKFIFDC_02501	411459.RUMOBE_02159	0.0	902.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,3Y03I@572511|Blautia	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase
HLKFIFDC_02502	411459.RUMOBE_02146	7.73e-14	70.9	COG1196@1|root,COG1196@2|Bacteria,1UHVD@1239|Firmicutes,25E44@186801|Clostridia,3Y28J@572511|Blautia	186801|Clostridia	D	Relaxase/Mobilisation nuclease domain	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
HLKFIFDC_02503	518637.EUBIFOR_00736	1.29e-84	249.0	2C2YH@1|root,2ZBKZ@2|Bacteria,1V3N8@1239|Firmicutes,3VTF7@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	MobC
HLKFIFDC_02504	411469.EUBHAL_00855	0.0	879.0	COG3225@1|root,COG3225@2|Bacteria,1TT1J@1239|Firmicutes,24BC2@186801|Clostridia,25VKY@186806|Eubacteriaceae	186801|Clostridia	N	ABC-type uncharacterized transport system	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3,ABC_transp_aux
HLKFIFDC_02505	411469.EUBHAL_00854	5.03e-197	547.0	COG1277@1|root,COG1277@2|Bacteria,1UZXS@1239|Firmicutes,248ME@186801|Clostridia,25ZDN@186806|Eubacteriaceae	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_2,ABC2_membrane_3,ABC2_membrane_5
HLKFIFDC_02506	411469.EUBHAL_00853	5.92e-238	657.0	COG1131@1|root,COG1131@2|Bacteria,1TQUS@1239|Firmicutes,25AZ1@186801|Clostridia,25VR0@186806|Eubacteriaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HLKFIFDC_02507	411469.EUBHAL_00852	0.0	894.0	COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,25UY5@186806|Eubacteriaceae	186801|Clostridia	C	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.2,1.4.1.3,1.4.1.4	ko:K00260,ko:K00261,ko:K00262	ko00220,ko00250,ko00430,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00430,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
HLKFIFDC_02508	411469.EUBHAL_00850	1.9e-109	315.0	COG1522@1|root,COG1522@2|Bacteria,1V3MI@1239|Firmicutes,24I1I@186801|Clostridia,25WEA@186806|Eubacteriaceae	186801|Clostridia	K	Cytoplasmic, score 8.87	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
HLKFIFDC_02509	411469.EUBHAL_00848	1.72e-98	286.0	COG1576@1|root,COG1576@2|Bacteria	2|Bacteria	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	MDMPI_N,SPOUT_MTase
HLKFIFDC_02511	411469.EUBHAL_00846	1.48e-289	790.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,25URE@186806|Eubacteriaceae	186801|Clostridia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
HLKFIFDC_02512	411469.EUBHAL_00845	0.0	1003.0	COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,2485G@186801|Clostridia,25VGN@186806|Eubacteriaceae	186801|Clostridia	S	Stage V sporulation protein B	spoVB	-	-	ko:K06409	-	-	-	-	ko00000,ko02000	2.A.66.2.14	-	-	Polysacc_synt,Polysacc_synt_C
HLKFIFDC_02513	411469.EUBHAL_00844	2.74e-101	293.0	COG1576@1|root,COG1576@2|Bacteria,1V3JM@1239|Firmicutes,24HED@186801|Clostridia,25WC9@186806|Eubacteriaceae	186801|Clostridia	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
HLKFIFDC_02514	411469.EUBHAL_00843	2.79e-143	407.0	COG2738@1|root,COG2738@2|Bacteria,1TPD3@1239|Firmicutes,2490Y@186801|Clostridia,25VGF@186806|Eubacteriaceae	186801|Clostridia	S	neutral zinc metallopeptidase	yugP	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
HLKFIFDC_02515	411469.EUBHAL_00842	8.17e-124	352.0	COG1853@1|root,COG1853@2|Bacteria,1V41U@1239|Firmicutes,24HTA@186801|Clostridia,25WPF@186806|Eubacteriaceae	186801|Clostridia	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
HLKFIFDC_02516	411469.EUBHAL_00841	1.48e-247	681.0	COG0371@1|root,COG0371@2|Bacteria,1TQFU@1239|Firmicutes,248KH@186801|Clostridia,25VZZ@186806|Eubacteriaceae	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	-	-	1.1.1.6	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	-	R01034,R10715,R10717	RC00029,RC00117,RC00670	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
HLKFIFDC_02517	411469.EUBHAL_00840	1.26e-289	790.0	COG0436@1|root,COG0436@2|Bacteria,1TP36@1239|Firmicutes,248ZV@186801|Clostridia,25VQ3@186806|Eubacteriaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	-	-	2.6.1.1	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
HLKFIFDC_02518	411469.EUBHAL_00839	0.0	1785.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,25ZN2@186806|Eubacteriaceae	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,Peptidase_S51,Response_reg,SBP_bac_3
HLKFIFDC_02519	411469.EUBHAL_00837	3.27e-184	512.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia,25V9G@186806|Eubacteriaceae	186801|Clostridia	E	ABC transporter, ATP-binding protein	glnQ	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
HLKFIFDC_02520	720554.Clocl_3766	2.37e-93	279.0	COG0765@1|root,COG0765@2|Bacteria,1V280@1239|Firmicutes,25C2S@186801|Clostridia,3WHKU@541000|Ruminococcaceae	186801|Clostridia	P	ABC transporter, permease protein	tcyB	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
HLKFIFDC_02521	411469.EUBHAL_00834	6.39e-196	545.0	COG0834@1|root,COG0834@2|Bacteria,1TQNR@1239|Firmicutes,249Y5@186801|Clostridia,25VIV@186806|Eubacteriaceae	186801|Clostridia	ET	ABC transporter, substrate-binding protein, family 3	fliY1	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
HLKFIFDC_02522	411469.EUBHAL_00832	0.0	1037.0	COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,248G1@186801|Clostridia,25UT1@186806|Eubacteriaceae	186801|Clostridia	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
HLKFIFDC_02523	411469.EUBHAL_00831	0.0	1136.0	COG3383@1|root,COG4624@1|root,COG3383@2|Bacteria,COG4624@2|Bacteria,1TP6C@1239|Firmicutes,24897@186801|Clostridia,25VMH@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	hydA1	-	1.12.1.3,1.6.5.3	ko:K00336,ko:K18332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_6,Fer4_7,NADH-G_4Fe-4S_3
HLKFIFDC_02524	411469.EUBHAL_00830	0.0	1290.0	COG1894@1|root,COG1894@2|Bacteria,1TQB0@1239|Firmicutes,2483E@186801|Clostridia,25UYC@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	nuoF2	-	1.12.1.3,1.17.1.11,1.6.5.3	ko:K00335,ko:K18331,ko:K22339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
HLKFIFDC_02525	411469.EUBHAL_00829	2.05e-109	315.0	COG1905@1|root,COG1905@2|Bacteria,1V4IR@1239|Firmicutes,25CD0@186801|Clostridia,25ZIW@186806|Eubacteriaceae	186801|Clostridia	C	Thioredoxin-like [2Fe-2S] ferredoxin	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
HLKFIFDC_02526	411469.EUBHAL_02285	0.0	951.0	COG0119@1|root,COG0119@2|Bacteria,1TP4Y@1239|Firmicutes,2495J@186801|Clostridia,25V5V@186806|Eubacteriaceae	186801|Clostridia	E	HMGL-like	-	GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0036440,GO:0046912,GO:0050450	-	-	-	-	-	-	-	-	-	iHN637.CLJU_RS03250	HMGL-like
HLKFIFDC_02527	411469.EUBHAL_02284	2.51e-145	410.0	COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,24JA2@186801|Clostridia,25WH3@186806|Eubacteriaceae	186801|Clostridia	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
HLKFIFDC_02528	411469.EUBHAL_02283	5.03e-314	856.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,2493T@186801|Clostridia,25VCW@186806|Eubacteriaceae	186801|Clostridia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
HLKFIFDC_02529	411469.EUBHAL_02282	0.0	891.0	COG1625@1|root,COG1625@2|Bacteria,1TSFU@1239|Firmicutes,247JK@186801|Clostridia,25VHQ@186806|Eubacteriaceae	186801|Clostridia	C	FeS-containing Cyanobacterial-specific oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DUF512
HLKFIFDC_02530	411469.EUBHAL_02281	9.49e-207	571.0	COG1496@1|root,COG1496@2|Bacteria,1TS34@1239|Firmicutes,248TD@186801|Clostridia,25VJY@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the multicopper oxidase YfiH RL5 family	yfiH	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
HLKFIFDC_02531	411469.EUBHAL_02280	3.69e-81	240.0	COG0792@1|root,COG0792@2|Bacteria,1VFHQ@1239|Firmicutes,24QNK@186801|Clostridia,25X8A@186806|Eubacteriaceae	186801|Clostridia	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
HLKFIFDC_02532	411469.EUBHAL_02279	5e-174	486.0	COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,248IT@186801|Clostridia,25VNF@186806|Eubacteriaceae	186801|Clostridia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
HLKFIFDC_02533	411469.EUBHAL_02278	3.89e-145	409.0	COG0681@1|root,COG0681@2|Bacteria,1UZ8V@1239|Firmicutes,25CN7@186801|Clostridia,25WUU@186806|Eubacteriaceae	186801|Clostridia	U	Signal peptidase, peptidase S26	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24
HLKFIFDC_02534	411469.EUBHAL_02277	7.28e-138	390.0	COG0681@1|root,COG0681@2|Bacteria,1UZ8V@1239|Firmicutes,25CN7@186801|Clostridia,25WUU@186806|Eubacteriaceae	186801|Clostridia	U	Signal peptidase, peptidase S26	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24
HLKFIFDC_02535	411469.EUBHAL_02276	1.91e-198	550.0	COG1161@1|root,COG1161@2|Bacteria,1TQGK@1239|Firmicutes,2490H@186801|Clostridia,25V2Z@186806|Eubacteriaceae	186801|Clostridia	S	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity	ylqF	-	-	ko:K14540	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1
HLKFIFDC_02536	411469.EUBHAL_02275	5.4e-116	333.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24MVR@186801|Clostridia,25WYS@186806|Eubacteriaceae	186801|Clostridia	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
HLKFIFDC_02537	411469.EUBHAL_02274	4.71e-74	222.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,24J83@186801|Clostridia,25WN4@186806|Eubacteriaceae	186801|Clostridia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
HLKFIFDC_02538	411469.EUBHAL_02273	1.57e-180	502.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,247JF@186801|Clostridia,25V0M@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
HLKFIFDC_02539	411469.EUBHAL_02272	3.33e-118	338.0	COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,24I1G@186801|Clostridia,25X91@186806|Eubacteriaceae	186801|Clostridia	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
HLKFIFDC_02540	411469.EUBHAL_02271	6.22e-43	140.0	COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,24QKN@186801|Clostridia,25X88@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the UPF0109 family	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
HLKFIFDC_02541	411469.EUBHAL_02270	5.2e-52	164.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,24MND@186801|Clostridia,25X5P@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
HLKFIFDC_02542	411469.EUBHAL_02269	7.42e-311	848.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,248EU@186801|Clostridia,25V24@186806|Eubacteriaceae	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
HLKFIFDC_02543	411469.EUBHAL_02268	1.56e-78	233.0	COG2739@1|root,COG2739@2|Bacteria,1VEGP@1239|Firmicutes,24QNM@186801|Clostridia,25X21@186806|Eubacteriaceae	186801|Clostridia	S	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein	-	-	-	ko:K09787	-	-	-	-	ko00000	-	-	-	UPF0122
HLKFIFDC_02544	411469.EUBHAL_02267	8.04e-129	365.0	COG1592@1|root,COG1592@2|Bacteria,1V1FF@1239|Firmicutes,248V2@186801|Clostridia,25W6N@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	rbr	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
HLKFIFDC_02545	1235790.C805_01371	1.01e-05	46.2	2DR14@1|root,339R7@2|Bacteria,1VMNT@1239|Firmicutes,24UVM@186801|Clostridia,25XYD@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02546	411469.EUBHAL_02264	1.38e-311	850.0	COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,247X2@186801|Clostridia,25V48@186806|Eubacteriaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
HLKFIFDC_02547	411469.EUBHAL_02263	1.2e-144	407.0	COG0406@1|root,COG0406@2|Bacteria,1VEMM@1239|Firmicutes,24GJW@186801|Clostridia,25WVH@186806|Eubacteriaceae	186801|Clostridia	G	Phosphoglycerate mutase family	cobC	-	3.1.3.73	ko:K02226	ko00860,ko01100,map00860,map01100	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
HLKFIFDC_02548	411469.EUBHAL_02262	8.19e-46	147.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,24QJE@186801|Clostridia,25X8C@186806|Eubacteriaceae	186801|Clostridia	K	'Cold-shock' DNA-binding domain	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
HLKFIFDC_02549	411469.EUBHAL_02261	6.69e-263	721.0	COG0628@1|root,COG0628@2|Bacteria,1TS4S@1239|Firmicutes,248E5@186801|Clostridia,25WGC@186806|Eubacteriaceae	186801|Clostridia	S	AI-2E family transporter	ytvI	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
HLKFIFDC_02550	411469.EUBHAL_02260	1.13e-229	633.0	28PM6@1|root,2ZCAA@2|Bacteria,1V4NT@1239|Firmicutes,24HIP@186801|Clostridia,25W92@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02551	411469.EUBHAL_02258	6.83e-109	313.0	2E62H@1|root,330RM@2|Bacteria,1VEY2@1239|Firmicutes,24T93@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02552	411469.EUBHAL_02257	1.21e-40	134.0	COG2155@1|root,COG2155@2|Bacteria,1VEQJ@1239|Firmicutes,24QKW@186801|Clostridia,25X9C@186806|Eubacteriaceae	186801|Clostridia	S	Domain of unknown function (DUF378)	-	-	-	ko:K09779	-	-	-	-	ko00000	-	-	-	DUF378
HLKFIFDC_02553	411469.EUBHAL_02255	1.92e-135	384.0	COG4290@1|root,COG4290@2|Bacteria,1V7IV@1239|Firmicutes,24JGG@186801|Clostridia,25XJR@186806|Eubacteriaceae	186801|Clostridia	F	ribonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuclease
HLKFIFDC_02554	1121024.AUCD01000071_gene282	5.01e-10	58.2	COG2732@1|root,COG2732@2|Bacteria,1VM0Z@1239|Firmicutes,4IRYM@91061|Bacilli	91061|Bacilli	K	Barstar (barnase inhibitor)	-	-	-	-	-	-	-	-	-	-	-	-	Barstar
HLKFIFDC_02555	411469.EUBHAL_02253	6.09e-275	752.0	COG3594@1|root,COG3594@2|Bacteria,1V6IX@1239|Firmicutes,25DT9@186801|Clostridia,25XZ1@186806|Eubacteriaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
HLKFIFDC_02565	411469.EUBHAL_02243	2.41e-29	108.0	2E4IR@1|root,32ZDT@2|Bacteria,1VENP@1239|Firmicutes,24RPR@186801|Clostridia,25XFV@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02566	411469.EUBHAL_02242	0.0	1430.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia,25VCX@186806|Eubacteriaceae	186801|Clostridia	L	DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
HLKFIFDC_02567	411469.EUBHAL_02241	7e-198	553.0	COG4260@1|root,COG4260@2|Bacteria,1TRYU@1239|Firmicutes,24901@186801|Clostridia,25VMD@186806|Eubacteriaceae	186801|Clostridia	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DZR,zf-ribbon_3,zinc_ribbon_2
HLKFIFDC_02568	411469.EUBHAL_02240	5.49e-142	401.0	COG0789@1|root,COG0789@2|Bacteria,1V1M9@1239|Firmicutes,24FUE@186801|Clostridia,25W89@186806|Eubacteriaceae	186801|Clostridia	K	Domain of unknown function (DUF1836)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1836
HLKFIFDC_02569	411469.EUBHAL_02239	7.31e-65	197.0	COG4496@1|root,COG4496@2|Bacteria,1VA04@1239|Firmicutes,24MX9@186801|Clostridia,25WVZ@186806|Eubacteriaceae	186801|Clostridia	S	TrpR family protein YerC YecD	-	-	-	-	-	-	-	-	-	-	-	-	Trp_repressor
HLKFIFDC_02570	411469.EUBHAL_02238	1.98e-175	488.0	COG1387@1|root,COG1387@2|Bacteria,1TQ33@1239|Firmicutes,249TZ@186801|Clostridia,25WCW@186806|Eubacteriaceae	186801|Clostridia	E	COG1387 Histidinol phosphatase and related hydrolases of the PHP family	-	-	-	ko:K04477	-	-	-	-	ko00000	-	-	-	PHP
HLKFIFDC_02571	411469.EUBHAL_02237	1.5e-227	626.0	COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,248DH@186801|Clostridia,25UQH@186806|Eubacteriaceae	186801|Clostridia	C	Belongs to the LDH MDH superfamily. LDH family	ldh	-	1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	-	R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
HLKFIFDC_02572	411469.EUBHAL_02236	1.02e-163	457.0	COG0535@1|root,COG0535@2|Bacteria,1V3MC@1239|Firmicutes,24I1P@186801|Clostridia,25ZK5@186806|Eubacteriaceae	186801|Clostridia	S	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM
HLKFIFDC_02573	411469.EUBHAL_02235	6.41e-197	545.0	COG2240@1|root,COG2240@2|Bacteria,1TRCR@1239|Firmicutes,24ABV@186801|Clostridia,25W20@186806|Eubacteriaceae	186801|Clostridia	H	Belongs to the pyridoxine kinase family	-	-	2.7.1.35	ko:K00868	ko00750,ko01100,map00750,map01100	-	R00174,R01909,R02493	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	Phos_pyr_kin
HLKFIFDC_02574	411469.EUBHAL_02234	1.21e-124	354.0	COG0622@1|root,COG0622@2|Bacteria,1VA0U@1239|Firmicutes,24MMK@186801|Clostridia,25WR2@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	yfcE1	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
HLKFIFDC_02575	411469.EUBHAL_02233	1.98e-183	511.0	COG0796@1|root,COG0796@2|Bacteria,1TPPR@1239|Firmicutes,249MB@186801|Clostridia,25W82@186806|Eubacteriaceae	186801|Clostridia	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
HLKFIFDC_02576	411469.EUBHAL_02231	3.59e-226	624.0	COG0715@1|root,COG0715@2|Bacteria,1TQN5@1239|Firmicutes,248IG@186801|Clostridia,25VGQ@186806|Eubacteriaceae	186801|Clostridia	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
HLKFIFDC_02577	411469.EUBHAL_02228	1.09e-169	474.0	COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,247NK@186801|Clostridia,25V1H@186806|Eubacteriaceae	186801|Clostridia	K	Transcriptional regulatory protein	yebC	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
HLKFIFDC_02578	411469.EUBHAL_02227	1.36e-286	782.0	COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,2491B@186801|Clostridia,25USW@186806|Eubacteriaceae	186801|Clostridia	E	Aminotransferase class I and II	dapL2	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
HLKFIFDC_02579	411469.EUBHAL_02226	9.89e-76	226.0	COG2337@1|root,COG2337@2|Bacteria,1V6DK@1239|Firmicutes,24JE1@186801|Clostridia,25WS1@186806|Eubacteriaceae	186801|Clostridia	L	Toxic component of a toxin-antitoxin (TA) module	ndoA	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
HLKFIFDC_02580	411469.EUBHAL_02225	0.0	978.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia,25UYP@186806|Eubacteriaceae	186801|Clostridia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	ACPS,Carb_kinase,YjeF_N
HLKFIFDC_02581	411469.EUBHAL_02223	1.99e-151	426.0	COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,247RQ@186801|Clostridia,25VIM@186806|Eubacteriaceae	186801|Clostridia	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
HLKFIFDC_02582	411469.EUBHAL_02221	0.0	1122.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia,25UY3@186806|Eubacteriaceae	186801|Clostridia	S	of ABC transporters with duplicated ATPase	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
HLKFIFDC_02584	411469.EUBHAL_02219	1.62e-94	276.0	COG3682@1|root,COG3682@2|Bacteria,1VHDV@1239|Firmicutes,25HPH@186801|Clostridia,25Z8X@186806|Eubacteriaceae	1239|Firmicutes	K	Transcriptional regulator, BlaI MecI CopY family	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
HLKFIFDC_02585	411469.EUBHAL_02218	4.92e-209	583.0	COG4219@1|root,COG4219@2|Bacteria,1TP3Z@1239|Firmicutes,249NV@186801|Clostridia,25VWV@186806|Eubacteriaceae	186801|Clostridia	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23,Peptidase_M56
HLKFIFDC_02586	411469.EUBHAL_02217	3.7e-101	293.0	COG1846@1|root,COG1846@2|Bacteria,1V6GY@1239|Firmicutes,24HTB@186801|Clostridia,25WME@186806|Eubacteriaceae	186801|Clostridia	K	Transcriptional regulator, MarR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
HLKFIFDC_02587	1280698.AUJS01000022_gene1305	3.86e-158	454.0	COG2070@1|root,COG2070@2|Bacteria,1TPX1@1239|Firmicutes,247YZ@186801|Clostridia,27V3C@189330|Dorea	186801|Clostridia	S	Nitronate monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
HLKFIFDC_02588	411469.EUBHAL_02214	0.0	1159.0	COG0777@1|root,COG0825@1|root,COG0777@2|Bacteria,COG0825@2|Bacteria,1TP4U@1239|Firmicutes,248QK@186801|Clostridia,25V1B@186806|Eubacteriaceae	186801|Clostridia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS20740	ACCA,Carboxyl_trans
HLKFIFDC_02589	411469.EUBHAL_02213	0.0	892.0	COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,25E48@186801|Clostridia,25V5Q@186806|Eubacteriaceae	186801|Clostridia	I	Acetyl-CoA carboxylase, biotin carboxylase subunit	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
HLKFIFDC_02590	411469.EUBHAL_02212	1.1e-98	286.0	COG0764@1|root,COG0764@2|Bacteria,1V6EX@1239|Firmicutes,24JAW@186801|Clostridia,25WHY@186806|Eubacteriaceae	186801|Clostridia	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
HLKFIFDC_02591	411469.EUBHAL_02211	6.35e-97	284.0	COG0511@1|root,COG0511@2|Bacteria,1VAB7@1239|Firmicutes,24MNP@186801|Clostridia,25XAJ@186806|Eubacteriaceae	186801|Clostridia	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	iHN637.CLJU_RS20755	Biotin_lipoyl
HLKFIFDC_02592	411469.EUBHAL_02210	7.99e-293	800.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,25UYT@186806|Eubacteriaceae	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
HLKFIFDC_02593	411469.EUBHAL_02209	1.19e-154	436.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,25VA9@186806|Eubacteriaceae	186801|Clostridia	IQ	Psort location Cytoplasmic, score	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
HLKFIFDC_02594	411469.EUBHAL_02208	7.61e-218	601.0	COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,247UF@186801|Clostridia,25VUM@186806|Eubacteriaceae	186801|Clostridia	I	Psort location Cytoplasmic, score	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
HLKFIFDC_02595	411469.EUBHAL_02207	6.44e-213	589.0	COG2070@1|root,COG2070@2|Bacteria,1TPC3@1239|Firmicutes,24831@186801|Clostridia,25USN@186806|Eubacteriaceae	186801|Clostridia	S	reductase II	fabK	-	1.3.1.9	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iHN637.CLJU_RS20775	NMO
HLKFIFDC_02596	411469.EUBHAL_02206	1.81e-41	136.0	COG0236@1|root,COG0236@2|Bacteria,1TU8C@1239|Firmicutes,25P5Z@186801|Clostridia,25XX1@186806|Eubacteriaceae	186801|Clostridia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
HLKFIFDC_02597	411469.EUBHAL_02205	2.38e-225	622.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,248V8@186801|Clostridia,25UU4@186806|Eubacteriaceae	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
HLKFIFDC_02598	1280698.AUJS01000008_gene873	2.16e-68	207.0	COG3070@1|root,COG3070@2|Bacteria,1V42M@1239|Firmicutes,24JNV@186801|Clostridia,27WUX@189330|Dorea	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
HLKFIFDC_02599	471875.RUMLAC_01047	4.26e-98	285.0	COG1846@1|root,COG1846@2|Bacteria,1V8KT@1239|Firmicutes,24B99@186801|Clostridia,3WGSA@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulators	mgrA	-	-	-	-	-	-	-	-	-	-	-	MarR
HLKFIFDC_02600	748224.HMPREF9436_03129	1.25e-172	480.0	COG4422@1|root,COG4422@2|Bacteria,1TPRY@1239|Firmicutes,247VT@186801|Clostridia,3WI0I@541000|Ruminococcaceae	186801|Clostridia	F	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5131
HLKFIFDC_02601	471875.RUMLAC_00973	1.38e-226	623.0	COG1533@1|root,COG1533@2|Bacteria,1TRIS@1239|Firmicutes,25CEW@186801|Clostridia,3WGZD@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
HLKFIFDC_02602	411469.EUBHAL_02588	1.47e-134	382.0	COG1309@1|root,COG1309@2|Bacteria,1TSUJ@1239|Firmicutes,25BJ1@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
HLKFIFDC_02603	411469.EUBHAL_02587	1.28e-189	529.0	COG0697@1|root,COG0697@2|Bacteria,1TPST@1239|Firmicutes,248K5@186801|Clostridia,25UWC@186806|Eubacteriaceae	186801|Clostridia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HLKFIFDC_02604	742765.HMPREF9457_03295	4.14e-94	275.0	COG0454@1|root,COG0456@2|Bacteria,1VAFS@1239|Firmicutes,24MUI@186801|Clostridia,27VXG@189330|Dorea	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	ko:K03826	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_10,Acetyltransf_7
HLKFIFDC_02605	411469.EUBHAL_02579	5.83e-155	434.0	COG0847@1|root,COG0847@2|Bacteria	2|Bacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
HLKFIFDC_02606	411469.EUBHAL_02578	3.96e-131	372.0	COG0400@1|root,COG0400@2|Bacteria,1VBK0@1239|Firmicutes,24N89@186801|Clostridia,25XBW@186806|Eubacteriaceae	186801|Clostridia	S	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02607	411469.EUBHAL_02576	1.5e-128	365.0	COG1896@1|root,COG1896@2|Bacteria,1V7E8@1239|Firmicutes,24DNC@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K06952	-	-	-	-	ko00000	-	-	-	DUF429,HD_3
HLKFIFDC_02608	411469.EUBHAL_02575	4.94e-75	224.0	COG1393@1|root,COG1393@2|Bacteria,1V6H8@1239|Firmicutes,24JH6@186801|Clostridia,25WP7@186806|Eubacteriaceae	186801|Clostridia	P	Belongs to the ArsC family	-	-	-	-	-	-	-	-	-	-	-	-	ArsC,Glutaredoxin
HLKFIFDC_02609	411469.EUBHAL_02573	0.0	1030.0	COG2871@1|root,COG3894@1|root,COG2871@2|Bacteria,COG3894@2|Bacteria,1TP0H@1239|Firmicutes,247S0@186801|Clostridia,25UZX@186806|Eubacteriaceae	186801|Clostridia	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
HLKFIFDC_02610	411469.EUBHAL_02572	1.84e-235	647.0	COG1879@1|root,COG1879@2|Bacteria,1TQW5@1239|Firmicutes,249PS@186801|Clostridia,25VXK@186806|Eubacteriaceae	186801|Clostridia	G	Periplasmic binding protein domain	-	-	-	ko:K10540	ko02010,ko02030,map02010,map02030	M00214	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.3	-	-	Peripla_BP_4
HLKFIFDC_02611	411469.EUBHAL_02571	1.83e-148	418.0	2C11U@1|root,33VPV@2|Bacteria,1VVR2@1239|Firmicutes,250UF@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02612	411469.EUBHAL_02569	0.0	1083.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,247XB@186801|Clostridia,25WPE@186806|Eubacteriaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,His_kinase,dCache_1
HLKFIFDC_02613	411469.EUBHAL_02568	0.0	1054.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TQCS@1239|Firmicutes,248SC@186801|Clostridia,25XBG@186806|Eubacteriaceae	186801|Clostridia	T	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Response_reg
HLKFIFDC_02614	411469.EUBHAL_02567	0.0	877.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,247VA@186801|Clostridia,25ZNV@186806|Eubacteriaceae	186801|Clostridia	G	Vacuole effluxer Atg22 like	lacS	-	-	ko:K03292,ko:K11104,ko:K16209	-	-	-	-	ko00000,ko02000	2.A.2,2.A.2.1,2.A.2.2	-	-	MFS_2
HLKFIFDC_02615	411469.EUBHAL_02566	9.98e-146	410.0	COG4123@1|root,COG4123@2|Bacteria,1UK35@1239|Firmicutes,25FHR@186801|Clostridia,25XJC@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
HLKFIFDC_02616	411469.EUBHAL_02565	1.22e-92	276.0	COG1937@1|root,COG1937@2|Bacteria,1VA7S@1239|Firmicutes,24NNH@186801|Clostridia,25XDV@186806|Eubacteriaceae	186801|Clostridia	S	Metal-sensitive transcriptional repressor	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
HLKFIFDC_02617	411469.EUBHAL_02564	3.02e-84	249.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,Lant_dehydr_N,MarR,MarR_2
HLKFIFDC_02618	411469.EUBHAL_02563	3.05e-138	391.0	COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249Z9@186801|Clostridia,25W68@186806|Eubacteriaceae	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
HLKFIFDC_02619	411469.EUBHAL_02562	0.0	1490.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia,25VTE@186806|Eubacteriaceae	186801|Clostridia	P	ABC transporter, ATP-binding protein	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HLKFIFDC_02620	411469.EUBHAL_02561	0.0	1161.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,25URG@186806|Eubacteriaceae	186801|Clostridia	V	ABC-type multidrug transport system, ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HLKFIFDC_02621	411469.EUBHAL_02560	3.74e-59	183.0	COG1396@1|root,COG1396@2|Bacteria,1VARC@1239|Firmicutes,24NFJ@186801|Clostridia,25YZG@186806|Eubacteriaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HLKFIFDC_02622	411469.EUBHAL_02559	3.9e-289	788.0	COG3550@1|root,COG3550@2|Bacteria,1TR9A@1239|Firmicutes,24C9K@186801|Clostridia,25XA1@186806|Eubacteriaceae	186801|Clostridia	S	HipA-like C-terminal domain	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
HLKFIFDC_02623	411469.EUBHAL_02558	5.12e-159	446.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,247TK@186801|Clostridia,25VZY@186806|Eubacteriaceae	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HLKFIFDC_02624	411469.EUBHAL_02557	0.0	934.0	COG0642@1|root,COG2205@2|Bacteria,1UYAJ@1239|Firmicutes,24CIQ@186801|Clostridia,25WG6@186806|Eubacteriaceae	186801|Clostridia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c_5,HisKA
HLKFIFDC_02625	411469.EUBHAL_02555	3.18e-101	293.0	COG0071@1|root,COG0071@2|Bacteria,1VG0E@1239|Firmicutes,24MRZ@186801|Clostridia,25WH5@186806|Eubacteriaceae	186801|Clostridia	O	Belongs to the small heat shock protein (HSP20) family	hsp18	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
HLKFIFDC_02626	411469.EUBHAL_02554	1.33e-95	278.0	COG0071@1|root,COG0071@2|Bacteria,1VG0E@1239|Firmicutes,24MRZ@186801|Clostridia,25WH5@186806|Eubacteriaceae	186801|Clostridia	O	Belongs to the small heat shock protein (HSP20) family	hsp18	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
HLKFIFDC_02627	411469.EUBHAL_02552	1.43e-148	432.0	COG0642@1|root,COG2205@2|Bacteria,1UHQC@1239|Firmicutes,25EVD@186801|Clostridia,25ZUN@186806|Eubacteriaceae	186801|Clostridia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
HLKFIFDC_02628	411469.EUBHAL_02551	1.06e-157	442.0	COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,248XH@186801|Clostridia,25W40@186806|Eubacteriaceae	186801|Clostridia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HLKFIFDC_02629	411469.EUBHAL_02549	4.91e-210	581.0	COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes,249SY@186801|Clostridia,25VM6@186806|Eubacteriaceae	186801|Clostridia	I	lipid kinase, YegS Rv2252 BmrU family	dagK	-	2.7.1.107	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_cat
HLKFIFDC_02630	411469.EUBHAL_00349	1.37e-308	841.0	COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,2485M@186801|Clostridia,25VBF@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
HLKFIFDC_02631	411469.EUBHAL_00799	0.0	869.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,25VW1@186806|Eubacteriaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	dacB_3	-	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	CW_binding_1,PBP5_C,Peptidase_S11
HLKFIFDC_02632	411469.EUBHAL_00800	1.7e-154	433.0	COG0220@1|root,COG0220@2|Bacteria,1TQCA@1239|Firmicutes,248YR@186801|Clostridia,25VT0@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
HLKFIFDC_02633	411469.EUBHAL_00802	1.69e-192	535.0	COG0561@1|root,COG0561@2|Bacteria,1TREF@1239|Firmicutes,24PNN@186801|Clostridia,25ZHR@186806|Eubacteriaceae	186801|Clostridia	S	Sucrose-6F-phosphate phosphohydrolase	yidA	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
HLKFIFDC_02635	1280671.AUJH01000004_gene3009	4.47e-08	63.5	COG4886@1|root,COG4886@2|Bacteria,1W0QU@1239|Firmicutes,253ET@186801|Clostridia,4C1TS@830|Butyrivibrio	186801|Clostridia	M	Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
HLKFIFDC_02637	411469.EUBHAL_00808	4.45e-100	328.0	COG1595@1|root,COG1595@2|Bacteria,1V8Z0@1239|Firmicutes,24KTC@186801|Clostridia	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2,WG_beta_rep,zinc_ribbon_2
HLKFIFDC_02639	411469.EUBHAL_00807	3.05e-170	474.0	COG1011@1|root,COG1011@2|Bacteria,1V3WC@1239|Firmicutes,24J13@186801|Clostridia,25XR4@186806|Eubacteriaceae	186801|Clostridia	S	HAD hydrolase, family IA, variant 1	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
HLKFIFDC_02640	411469.EUBHAL_00808	0.0	1484.0	COG1595@1|root,COG1595@2|Bacteria,1V8Z0@1239|Firmicutes,24KTC@186801|Clostridia	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2,WG_beta_rep,zinc_ribbon_2
HLKFIFDC_02641	411469.EUBHAL_00809	1.61e-184	514.0	COG0619@1|root,COG0619@2|Bacteria,1V0B0@1239|Firmicutes,24A4J@186801|Clostridia,25VX4@186806|Eubacteriaceae	186801|Clostridia	P	Cobalt transport protein	cbiQ	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
HLKFIFDC_02642	411469.EUBHAL_00810	2.94e-200	554.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia,25VQP@186806|Eubacteriaceae	186801|Clostridia	P	Part of an ABC transporter complex. Responsible for energy coupling to the transport system	cbiO	-	-	ko:K02006	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
HLKFIFDC_02643	411460.RUMTOR_00305	1.74e-118	345.0	COG0310@1|root,COG0310@2|Bacteria,1TQVK@1239|Firmicutes,248ZZ@186801|Clostridia,3XYU1@572511|Blautia	186801|Clostridia	P	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import	cbiM	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM
HLKFIFDC_02644	411469.EUBHAL_00813	1.18e-72	218.0	COG1930@1|root,COG1930@2|Bacteria,1VF03@1239|Firmicutes,24MYG@186801|Clostridia,25WWK@186806|Eubacteriaceae	186801|Clostridia	P	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import	cbiN	-	-	ko:K02009	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18	-	-	CbiN
HLKFIFDC_02645	411469.EUBHAL_00814	1.78e-126	360.0	COG1611@1|root,COG1611@2|Bacteria,1UKED@1239|Firmicutes,24DSN@186801|Clostridia,25XES@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the LOG family	yvdD	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
HLKFIFDC_02646	411469.EUBHAL_00815	2.86e-140	396.0	COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249Z9@186801|Clostridia,25W68@186806|Eubacteriaceae	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
HLKFIFDC_02648	411469.EUBHAL_00817	1.27e-221	610.0	COG0175@1|root,COG0175@2|Bacteria,1U1VN@1239|Firmicutes,248Y9@186801|Clostridia,25VBR@186806|Eubacteriaceae	186801|Clostridia	H	Psort location Cytoplasmic, score	cysD	-	1.8.4.10,1.8.4.8,2.7.7.4	ko:K00390,ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R02021,R04929	RC00007,RC02809,RC02862,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
HLKFIFDC_02649	411469.EUBHAL_00818	0.0	1201.0	COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,1TQXK@1239|Firmicutes,25EK3@186801|Clostridia,25ZJY@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.1.25,2.7.7.4	ko:K00955	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU,GTP_EFTU_D3
HLKFIFDC_02650	411469.EUBHAL_00819	0.0	928.0	COG1874@1|root,COG1874@2|Bacteria,1V23M@1239|Firmicutes,24GDA@186801|Clostridia	2|Bacteria	G	Beta-galactosidase	-	-	3.2.1.23	ko:K01190,ko:K12308	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Cellulase,DUF4832,GHL6,Glyco_hydro_42,Glyco_hydro_42M
HLKFIFDC_02651	411469.EUBHAL_00821	0.0	926.0	COG2059@1|root,COG2059@2|Bacteria,1V42U@1239|Firmicutes,24HA0@186801|Clostridia,25WPT@186806|Eubacteriaceae	186801|Clostridia	P	CytoplasmicMembrane, score 9.99	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
HLKFIFDC_02652	411469.EUBHAL_00822	0.0	1053.0	COG0714@1|root,COG0714@2|Bacteria,1U8NZ@1239|Firmicutes,248X1@186801|Clostridia,25V8J@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
HLKFIFDC_02653	411469.EUBHAL_00823	4.86e-316	860.0	COG3864@1|root,COG3864@2|Bacteria,1TSI1@1239|Firmicutes,248YT@186801|Clostridia,25VHT@186806|Eubacteriaceae	186801|Clostridia	S	VWA-like domain (DUF2201)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
HLKFIFDC_02654	411469.EUBHAL_00824	1.25e-282	772.0	28KXK@1|root,2ZADH@2|Bacteria,1V79T@1239|Firmicutes,24K1T@186801|Clostridia,25X00@186806|Eubacteriaceae	186801|Clostridia	S	Leucine rich repeats (6 copies)	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
HLKFIFDC_02655	411469.EUBHAL_00826	7.44e-185	514.0	COG0345@1|root,COG0345@2|Bacteria,1TP1E@1239|Firmicutes,247SR@186801|Clostridia,25V06@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
HLKFIFDC_02657	411469.EUBHAL_00828	1.87e-297	808.0	COG1619@1|root,COG1619@2|Bacteria,1TZSN@1239|Firmicutes,25CIH@186801|Clostridia,25VYX@186806|Eubacteriaceae	186801|Clostridia	V	LD-carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S66
HLKFIFDC_02658	411469.EUBHAL_00328	4.34e-188	521.0	COG0708@1|root,COG0708@2|Bacteria,1TPFB@1239|Firmicutes,24849@186801|Clostridia,25V2W@186806|Eubacteriaceae	186801|Clostridia	L	exodeoxyribonuclease III	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
HLKFIFDC_02659	411469.EUBHAL_00329	9.37e-129	365.0	COG1335@1|root,COG1335@2|Bacteria,1V1CY@1239|Firmicutes,24HQM@186801|Clostridia,25WAI@186806|Eubacteriaceae	186801|Clostridia	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
HLKFIFDC_02660	411469.EUBHAL_00330	1.42e-255	701.0	COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,248IA@186801|Clostridia,25VJ9@186806|Eubacteriaceae	186801|Clostridia	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
HLKFIFDC_02661	411469.EUBHAL_00331	4.44e-55	171.0	2E3FD@1|root,32YE7@2|Bacteria,1VEE4@1239|Firmicutes,24QJ7@186801|Clostridia,25XED@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TSCPD
HLKFIFDC_02662	411469.EUBHAL_00332	7.3e-162	454.0	COG0775@1|root,COG0775@2|Bacteria,1U7WK@1239|Firmicutes,247U5@186801|Clostridia,25W3M@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	mtnN	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
HLKFIFDC_02663	411469.EUBHAL_00333	1.38e-148	419.0	2EICA@1|root,334KH@2|Bacteria,1VIYE@1239|Firmicutes,24T0X@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02664	411469.EUBHAL_00334	1.27e-189	528.0	COG0726@1|root,COG0726@2|Bacteria,1TT1X@1239|Firmicutes,249PF@186801|Clostridia,25VJ8@186806|Eubacteriaceae	186801|Clostridia	G	Polysaccharide deacetylase	pdaA	-	-	ko:K01567	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
HLKFIFDC_02665	411469.EUBHAL_00336	4.06e-127	362.0	COG1971@1|root,COG1971@2|Bacteria,1V4QK@1239|Firmicutes,24FY0@186801|Clostridia,25WMT@186806|Eubacteriaceae	186801|Clostridia	P	Probably functions as a manganese efflux pump	mntP	-	-	-	-	-	-	-	-	-	-	-	Mntp
HLKFIFDC_02666	411469.EUBHAL_00337	1.74e-61	188.0	2CGVU@1|root,32S4Q@2|Bacteria,1V9YX@1239|Firmicutes,24NX8@186801|Clostridia,25X8P@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02667	411469.EUBHAL_00338	3.84e-264	723.0	COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,247SM@186801|Clostridia,25VKP@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
HLKFIFDC_02668	411469.EUBHAL_00339	4.44e-134	379.0	2ADZG@1|root,313RY@2|Bacteria,1V6JT@1239|Firmicutes,24JCA@186801|Clostridia,25XK5@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF1256)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1256
HLKFIFDC_02669	411469.EUBHAL_00341	4.95e-256	706.0	COG1388@1|root,COG1388@2|Bacteria,1V4FJ@1239|Firmicutes,24IPI@186801|Clostridia,25X3B@186806|Eubacteriaceae	186801|Clostridia	M	LysM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LysM
HLKFIFDC_02670	411469.EUBHAL_00342	6.01e-288	786.0	2C3W5@1|root,2ZBIU@2|Bacteria,1UZRE@1239|Firmicutes,24BHB@186801|Clostridia,25VTG@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02671	411469.EUBHAL_02204	4.63e-174	486.0	COG0428@1|root,COG0428@2|Bacteria,1TP7J@1239|Firmicutes,247Q2@186801|Clostridia,25V37@186806|Eubacteriaceae	186801|Clostridia	P	Metal cation transporter, ZIP family	gufA	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
HLKFIFDC_02672	411469.EUBHAL_02901	0.0	1310.0	COG0855@1|root,COG0855@2|Bacteria,1TNZM@1239|Firmicutes,248XY@186801|Clostridia,25UWP@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk1	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
HLKFIFDC_02673	411469.EUBHAL_02900	4.68e-193	535.0	COG3608@1|root,COG3608@2|Bacteria,1TRKT@1239|Firmicutes,2492W@186801|Clostridia,25VIW@186806|Eubacteriaceae	186801|Clostridia	S	Selenium-dependent molybdenum hydroxylase system protein, YqeB family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	NTP_transf_3
HLKFIFDC_02674	411469.EUBHAL_02899	9.11e-198	548.0	COG1763@1|root,COG1763@2|Bacteria,1VAIZ@1239|Firmicutes,24N6J@186801|Clostridia,25XWH@186806|Eubacteriaceae	186801|Clostridia	H	selenium-dependent hydroxylase accessory protein YqeC	yqeC	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02675	411469.EUBHAL_02898	3.82e-141	399.0	COG0503@1|root,COG0503@2|Bacteria,1V1DU@1239|Firmicutes,249VC@186801|Clostridia,25W3I@186806|Eubacteriaceae	186801|Clostridia	F	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis	xpt	-	2.4.2.22	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01229,R02142	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
HLKFIFDC_02676	411469.EUBHAL_02897	2.51e-150	422.0	COG2068@1|root,COG2068@2|Bacteria,1VA0F@1239|Firmicutes,24KIZ@186801|Clostridia,25XFM@186806|Eubacteriaceae	186801|Clostridia	S	MobA-like NTP transferase domain	ygfJ	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
HLKFIFDC_02677	411469.EUBHAL_02896	0.0	1501.0	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,25VMN@186806|Eubacteriaceae	186801|Clostridia	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	xdhD	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
HLKFIFDC_02678	411469.EUBHAL_02895	6.46e-109	313.0	COG2080@1|root,COG2080@2|Bacteria,1V6HE@1239|Firmicutes,24HQN@186801|Clostridia,25WB9@186806|Eubacteriaceae	186801|Clostridia	C	[2Fe-2S] binding domain	hcrC	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
HLKFIFDC_02679	411469.EUBHAL_02894	1.3e-179	500.0	COG1319@1|root,COG1319@2|Bacteria,1TSNH@1239|Firmicutes,24A57@186801|Clostridia,25WAS@186806|Eubacteriaceae	186801|Clostridia	C	FAD binding domain in molybdopterin dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5
HLKFIFDC_02680	411469.EUBHAL_02893	8.05e-127	362.0	2DSF9@1|root,33FXN@2|Bacteria,1VNVI@1239|Firmicutes,24VSH@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02681	411469.EUBHAL_02891	6.99e-303	834.0	COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,248G8@186801|Clostridia,25V9A@186806|Eubacteriaceae	186801|Clostridia	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
HLKFIFDC_02682	411469.EUBHAL_01261	1.63e-133	379.0	COG2137@1|root,COG2137@2|Bacteria,1V72V@1239|Firmicutes,24J7X@186801|Clostridia,25WSX@186806|Eubacteriaceae	186801|Clostridia	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
HLKFIFDC_02683	411469.EUBHAL_01260	2.74e-266	730.0	COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,247SF@186801|Clostridia,25UYG@186806|Eubacteriaceae	186801|Clostridia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
HLKFIFDC_02684	411469.EUBHAL_01259	7.34e-124	352.0	COG0780@1|root,COG0780@2|Bacteria,1TPYC@1239|Firmicutes,24BYP@186801|Clostridia,25VJQ@186806|Eubacteriaceae	186801|Clostridia	S	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
HLKFIFDC_02686	411469.EUBHAL_01257	6.25e-122	347.0	COG0262@1|root,COG0262@2|Bacteria,1VB80@1239|Firmicutes,24FTH@186801|Clostridia,25WEW@186806|Eubacteriaceae	186801|Clostridia	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
HLKFIFDC_02687	411469.EUBHAL_01256	2.01e-206	570.0	COG0207@1|root,COG0207@2|Bacteria,1TSIR@1239|Firmicutes,249QG@186801|Clostridia,25VH7@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
HLKFIFDC_02689	411469.EUBHAL_01254	3.6e-208	575.0	COG1281@1|root,COG1281@2|Bacteria,1TRCH@1239|Firmicutes,24940@186801|Clostridia,25UQP@186806|Eubacteriaceae	186801|Clostridia	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
HLKFIFDC_02690	411469.EUBHAL_01253	8.34e-179	498.0	COG4976@1|root,COG4976@2|Bacteria,1UHZM@1239|Firmicutes,24A6U@186801|Clostridia,25VX0@186806|Eubacteriaceae	186801|Clostridia	S	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
HLKFIFDC_02691	411469.EUBHAL_01252	0.0	1018.0	COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,247UR@186801|Clostridia,25UTH@186806|Eubacteriaceae	186801|Clostridia	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	cls1	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
HLKFIFDC_02692	411469.EUBHAL_01251	0.0	2358.0	COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,248ZF@186801|Clostridia,25VUB@186806|Eubacteriaceae	186801|Clostridia	L	ATP-dependent helicase nuclease subunit A	addA	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
HLKFIFDC_02693	411469.EUBHAL_01250	0.0	2219.0	COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,2487T@186801|Clostridia,25V6H@186806|Eubacteriaceae	186801|Clostridia	L	ATP-dependent helicase deoxyribonuclease subunit B	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
HLKFIFDC_02694	411469.EUBHAL_01249	3.38e-252	692.0	COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,247N1@186801|Clostridia,25UW0@186806|Eubacteriaceae	186801|Clostridia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06430	GcpE
HLKFIFDC_02695	411469.EUBHAL_01248	8.76e-238	655.0	COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,247MT@186801|Clostridia,25VUG@186806|Eubacteriaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
HLKFIFDC_02696	411469.EUBHAL_01247	5.71e-262	719.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,2483M@186801|Clostridia,25UXN@186806|Eubacteriaceae	186801|Clostridia	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06420	DXPR_C,DXP_redisom_C,DXP_reductoisom
HLKFIFDC_02697	411469.EUBHAL_01246	5.12e-176	492.0	COG0575@1|root,COG0575@2|Bacteria,1UPNB@1239|Firmicutes,248BP@186801|Clostridia,25W3G@186806|Eubacteriaceae	186801|Clostridia	I	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
HLKFIFDC_02698	411469.EUBHAL_01245	3.42e-176	490.0	COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,247TE@186801|Clostridia,25VD6@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
HLKFIFDC_02699	411469.EUBHAL_01243	5.83e-118	338.0	COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,24HWS@186801|Clostridia,25WFH@186806|Eubacteriaceae	186801|Clostridia	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
HLKFIFDC_02700	411469.EUBHAL_01242	4.13e-166	464.0	COG0528@1|root,COG0528@2|Bacteria,1TPXN@1239|Firmicutes,247KR@186801|Clostridia,25VEN@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
HLKFIFDC_02702	411469.EUBHAL_03191	5.28e-166	463.0	COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,24J27@186801|Clostridia,25ZN5@186806|Eubacteriaceae	186801|Clostridia	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
HLKFIFDC_02703	411469.EUBHAL_03189	7.38e-252	691.0	COG0544@1|root,COG0544@2|Bacteria,1V3TE@1239|Firmicutes,24AAA@186801|Clostridia,25W8C@186806|Eubacteriaceae	186801|Clostridia	M	COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	tig_1	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C
HLKFIFDC_02705	411469.EUBHAL_03187	5.18e-166	467.0	COG2091@1|root,COG2091@2|Bacteria,1VEYZ@1239|Firmicutes,24RQ3@186801|Clostridia,25XE5@186806|Eubacteriaceae	186801|Clostridia	H	4'-phosphopantetheinyl transferase superfamily	sfp	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
HLKFIFDC_02706	411469.EUBHAL_03186	1.28e-65	199.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,25WU9@186806|Eubacteriaceae	186801|Clostridia	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
HLKFIFDC_02707	411469.EUBHAL_03185	9.52e-65	196.0	COG0675@1|root,COG0675@2|Bacteria	2|Bacteria	L	Transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
HLKFIFDC_02708	411469.EUBHAL_03184	4.81e-210	582.0	COG0697@1|root,COG0697@2|Bacteria,1TR6G@1239|Firmicutes,24AMC@186801|Clostridia,25WT9@186806|Eubacteriaceae	186801|Clostridia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HLKFIFDC_02711	411469.EUBHAL_03181	1.34e-139	397.0	2EJ36@1|root,33CUD@2|Bacteria,1VKX6@1239|Firmicutes,24UYD@186801|Clostridia,25Z0C@186806|Eubacteriaceae	186801|Clostridia	S	Pilin isopeptide linkage domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FctA
HLKFIFDC_02712	411469.EUBHAL_03180	1.92e-184	513.0	COG4509@1|root,COG4509@2|Bacteria,1V2EF@1239|Firmicutes,24CIH@186801|Clostridia,25W42@186806|Eubacteriaceae	186801|Clostridia	S	sortase, SrtB family	-	-	3.4.22.70	ko:K08600	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
HLKFIFDC_02713	411469.EUBHAL_03179	1.31e-233	645.0	2E1Y2@1|root,32X6Y@2|Bacteria,1UK76@1239|Firmicutes,24Q89@186801|Clostridia,25XMQ@186806|Eubacteriaceae	186801|Clostridia	S	Spy0128-like isopeptide containing domain	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02714	411469.EUBHAL_03178	4.98e-112	322.0	COG0681@1|root,COG0681@2|Bacteria,1V954@1239|Firmicutes,24JWF@186801|Clostridia,25WTJ@186806|Eubacteriaceae	186801|Clostridia	U	Belongs to the peptidase S26 family	lepB_2	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24,Peptidase_S26
HLKFIFDC_02715	411469.EUBHAL_03177	0.0	1800.0	COG2304@1|root,COG2304@2|Bacteria,1VAYN@1239|Firmicutes,24NPG@186801|Clostridia,25XQJ@186806|Eubacteriaceae	186801|Clostridia	M	Psort location Cellwall, score	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
HLKFIFDC_02716	411469.EUBHAL_00103	3.37e-272	745.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,25UQC@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	fucO	-	1.1.1.1,1.1.1.77	ko:K00048,ko:K13954	ko00010,ko00071,ko00350,ko00625,ko00626,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00630,map00640,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R01781,R02257,R04880,R05233,R05234,R06917,R06927	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
HLKFIFDC_02717	411469.EUBHAL_00101	1.04e-218	602.0	COG1404@1|root,COG1404@2|Bacteria,1TQRU@1239|Firmicutes,249H1@186801|Clostridia,25W3J@186806|Eubacteriaceae	186801|Clostridia	O	Belongs to the peptidase S8 family	aprX	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S8
HLKFIFDC_02718	411469.EUBHAL_00100	0.0	996.0	COG0457@1|root,COG0457@2|Bacteria,1TTVC@1239|Firmicutes,24ESN@186801|Clostridia,25W86@186806|Eubacteriaceae	186801|Clostridia	S	Domain of unknown function (DUF4037)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4037,DUF4125,TPR_10,TPR_12,TPR_7,TPR_8
HLKFIFDC_02719	1235802.C823_00056	1.96e-09	59.7	COG0069@1|root,COG0069@2|Bacteria,1TPVM@1239|Firmicutes,2487M@186801|Clostridia,25VQC@186806|Eubacteriaceae	186801|Clostridia	E	Conserved region in glutamate synthase	-	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase,Rubredoxin
HLKFIFDC_02720	411469.EUBHAL_00098	6.79e-141	397.0	COG0693@1|root,COG0693@2|Bacteria,1V25E@1239|Firmicutes,24JRD@186801|Clostridia,25ZGG@186806|Eubacteriaceae	186801|Clostridia	S	Intracellular protease, PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
HLKFIFDC_02721	411469.EUBHAL_00097	4.54e-138	390.0	2DM2Z@1|root,31HGC@2|Bacteria,1VAI4@1239|Firmicutes,24N79@186801|Clostridia,25YUX@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF4125)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4125
HLKFIFDC_02723	411469.EUBHAL_00094	3.53e-84	248.0	arCOG10654@1|root,32SVP@2|Bacteria,1VCYZ@1239|Firmicutes,24PR9@186801|Clostridia,25XGK@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02724	411469.EUBHAL_00092	4.01e-236	650.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TRD9@1239|Firmicutes,24CDE@186801|Clostridia	186801|Clostridia	KT	transcriptional regulator (AraC family)	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC,Response_reg
HLKFIFDC_02725	411469.EUBHAL_00091	3.47e-286	783.0	COG3275@1|root,COG4936@1|root,COG3275@2|Bacteria,COG4936@2|Bacteria,1VTXF@1239|Firmicutes,25E5Z@186801|Clostridia	186801|Clostridia	T	Histidine kinase	lytS	-	2.7.13.3	ko:K02478,ko:K07704	ko02020,map02020	M00492	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	5TM-5TMR_LYT,GAF_3,HATPase_c,His_kinase,SpoVT_C
HLKFIFDC_02726	411469.EUBHAL_00090	1.78e-82	243.0	COG0662@1|root,COG0662@2|Bacteria,1UI0P@1239|Firmicutes,24SCP@186801|Clostridia,25XPF@186806|Eubacteriaceae	186801|Clostridia	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
HLKFIFDC_02727	411469.EUBHAL_00089	4.21e-285	779.0	COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,248QF@186801|Clostridia,25V3W@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	-	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
HLKFIFDC_02728	411469.EUBHAL_00088	5.84e-220	607.0	COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,24871@186801|Clostridia,25W5G@186806|Eubacteriaceae	186801|Clostridia	C	glycyl-radical enzyme activating protein family	pflC	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
HLKFIFDC_02729	411469.EUBHAL_00087	0.0	1748.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25YA2@186806|Eubacteriaceae	186801|Clostridia	H	Pyruvate formate lyase-like	-	-	2.3.1.54,4.3.99.4	ko:K00656,ko:K20038	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
HLKFIFDC_02730	411469.EUBHAL_00085	0.0	880.0	COG3383@1|root,COG4624@1|root,COG3383@2|Bacteria,COG4624@2|Bacteria,1TP6C@1239|Firmicutes,25E8M@186801|Clostridia,25ZQA@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer4,Rubrerythrin
HLKFIFDC_02731	411469.EUBHAL_00084	0.0	1310.0	COG0369@1|root,COG1151@2|Bacteria,1TRSC@1239|Firmicutes,248HQ@186801|Clostridia,25UUE@186806|Eubacteriaceae	186801|Clostridia	C	Carbon-monoxide dehydrogenase, catalytic subunit	cooS	-	1.2.7.4	ko:K00198	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	M00377	R07157,R08034	RC00250,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Prismane
HLKFIFDC_02733	411469.EUBHAL_00081	2.31e-243	667.0	COG3049@1|root,COG3049@2|Bacteria,1TPZS@1239|Firmicutes,24B0E@186801|Clostridia,25UVN@186806|Eubacteriaceae	186801|Clostridia	M	Choloylglycine hydrolase	cbh	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	CBAH
HLKFIFDC_02734	411469.EUBHAL_00080	3.58e-162	453.0	29PCB@1|root,30AAJ@2|Bacteria,1V4H2@1239|Firmicutes,24IF4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02736	411469.EUBHAL_01504	2.41e-220	613.0	COG0803@1|root,COG0803@2|Bacteria,1TPG7@1239|Firmicutes,249VZ@186801|Clostridia,25VJF@186806|Eubacteriaceae	186801|Clostridia	P	ABC transporter, substrate-binding protein	-	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
HLKFIFDC_02737	411469.EUBHAL_01505	9.63e-169	472.0	COG1121@1|root,COG1121@2|Bacteria,1TQ68@1239|Firmicutes,248F1@186801|Clostridia,25W5W@186806|Eubacteriaceae	186801|Clostridia	P	ABC transporter, ATP-binding protein	-	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
HLKFIFDC_02738	411469.EUBHAL_01506	8.01e-175	490.0	COG1108@1|root,COG1108@2|Bacteria,1TR79@1239|Firmicutes,24875@186801|Clostridia,25V63@186806|Eubacteriaceae	186801|Clostridia	P	ABC 3 transport family	-	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
HLKFIFDC_02740	411469.EUBHAL_01509	0.0	1923.0	COG1026@1|root,COG1026@2|Bacteria,1TPD1@1239|Firmicutes,25NQ9@186801|Clostridia,25UTS@186806|Eubacteriaceae	186801|Clostridia	S	Peptidase M16 inactive domain	-	-	-	ko:K06972	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M16C_assoc,Peptidase_M16,Peptidase_M16_C
HLKFIFDC_02741	411469.EUBHAL_01510	6.74e-213	588.0	COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,24876@186801|Clostridia,25VJE@186806|Eubacteriaceae	186801|Clostridia	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
HLKFIFDC_02742	411469.EUBHAL_01511	1.9e-175	489.0	COG1381@1|root,COG1381@2|Bacteria,1UZ19@1239|Firmicutes,249TI@186801|Clostridia,25WGP@186806|Eubacteriaceae	186801|Clostridia	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
HLKFIFDC_02743	411469.EUBHAL_01513	0.0	970.0	COG0423@1|root,COG0423@2|Bacteria,1TP94@1239|Firmicutes,248FB@186801|Clostridia,25V91@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
HLKFIFDC_02744	411469.EUBHAL_01514	0.0	1394.0	COG3968@1|root,COG3968@2|Bacteria,1UHUF@1239|Firmicutes,2481B@186801|Clostridia,25V9J@186806|Eubacteriaceae	186801|Clostridia	S	Glutamate--ammonia ligase, catalytic domain protein	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
HLKFIFDC_02745	411469.EUBHAL_01515	5.22e-312	850.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,25V6Z@186806|Eubacteriaceae	186801|Clostridia	H	Folylpolyglutamate synthase	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
HLKFIFDC_02746	411469.EUBHAL_01516	5.05e-192	533.0	COG0294@1|root,COG0294@2|Bacteria,1TPKT@1239|Firmicutes,248BE@186801|Clostridia,25V52@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS03115	Pterin_bind
HLKFIFDC_02747	411469.EUBHAL_01517	4.88e-197	546.0	COG0801@1|root,COG1539@1|root,COG0801@2|Bacteria,COG1539@2|Bacteria,1V6PR@1239|Firmicutes,249YP@186801|Clostridia,25W0A@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folK	-	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB,HPPK
HLKFIFDC_02748	411469.EUBHAL_01518	1.23e-273	748.0	COG0077@1|root,COG0077@2|Bacteria,1TPDN@1239|Firmicutes,248G7@186801|Clostridia,25VRD@186806|Eubacteriaceae	186801|Clostridia	E	Prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
HLKFIFDC_02749	411469.EUBHAL_01519	0.0	1638.0	COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,2480C@186801|Clostridia,25VK6@186806|Eubacteriaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
HLKFIFDC_02750	411469.EUBHAL_01520	0.0	988.0	COG0248@1|root,COG0248@2|Bacteria,1TS3I@1239|Firmicutes,248EW@186801|Clostridia,25VUP@186806|Eubacteriaceae	186801|Clostridia	FP	Ppx/GppA phosphatase family	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
HLKFIFDC_02751	411469.EUBHAL_01521	0.0	1418.0	COG0855@1|root,COG0855@2|Bacteria,1TNZM@1239|Firmicutes,248XY@186801|Clostridia,25UWP@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
HLKFIFDC_02752	411469.EUBHAL_01522	2.64e-285	780.0	COG1472@1|root,COG1472@2|Bacteria,1TP63@1239|Firmicutes,24YIP@186801|Clostridia,25W9X@186806|Eubacteriaceae	186801|Clostridia	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
HLKFIFDC_02753	411469.EUBHAL_01523	0.0	961.0	COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,247RF@186801|Clostridia,25VI2@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
HLKFIFDC_02754	411469.EUBHAL_01524	0.0	932.0	COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia,25V1Q@186806|Eubacteriaceae	186801|Clostridia	F	adenylosuccinate lyase	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
HLKFIFDC_02755	411469.EUBHAL_01525	0.0	1024.0	COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,2485G@186801|Clostridia,25VCU@186806|Eubacteriaceae	186801|Clostridia	S	Membrane protein involved in the export of O-antigen and teichoic acid	spoVB1	-	-	ko:K06409	-	-	-	-	ko00000,ko02000	2.A.66.2.14	-	-	Polysacc_synt,Polysacc_synt_C
HLKFIFDC_02756	411469.EUBHAL_01526	0.0	869.0	COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,247RN@186801|Clostridia,25V6G@186806|Eubacteriaceae	186801|Clostridia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
HLKFIFDC_02757	411469.EUBHAL_01527	5.16e-248	680.0	COG0463@1|root,COG0463@2|Bacteria,1TT6C@1239|Firmicutes,248F2@186801|Clostridia,25V0I@186806|Eubacteriaceae	186801|Clostridia	M	Psort location Cytoplasmic, score	kfoC_2	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HLKFIFDC_02758	411469.EUBHAL_01528	3.16e-85	251.0	COG5341@1|root,COG5341@2|Bacteria,1VEPD@1239|Firmicutes,24QPH@186801|Clostridia,25XN3@186806|Eubacteriaceae	186801|Clostridia	S	NusG domain II	-	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	NusG_II
HLKFIFDC_02759	411469.EUBHAL_01529	2.09e-303	828.0	COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24805@186801|Clostridia,25VI9@186806|Eubacteriaceae	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4,Fer4_10,Fer4_7,Fer4_9,RnfC_N,SLBB
HLKFIFDC_02760	411469.EUBHAL_01530	1.28e-225	622.0	COG4658@1|root,COG4658@2|Bacteria,1TQAY@1239|Firmicutes,247TM@186801|Clostridia,25V0Y@186806|Eubacteriaceae	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfD	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
HLKFIFDC_02761	411469.EUBHAL_01531	2.04e-134	382.0	COG4659@1|root,COG4659@2|Bacteria,1V4CE@1239|Firmicutes,25CQS@186801|Clostridia,25ZJ7@186806|Eubacteriaceae	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfG	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
HLKFIFDC_02762	411469.EUBHAL_01532	1.22e-170	477.0	COG4660@1|root,COG4660@2|Bacteria,1TSE7@1239|Firmicutes,24972@186801|Clostridia,25VAT@186806|Eubacteriaceae	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfE	-	-	ko:K03613	-	-	-	-	ko00000	-	-	iHN637.CLJU_RS05585	Rnf-Nqr
HLKFIFDC_02763	411469.EUBHAL_01533	4.52e-120	344.0	COG4657@1|root,COG4657@2|Bacteria,1TS06@1239|Firmicutes,247UE@186801|Clostridia,25VXE@186806|Eubacteriaceae	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfA	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
HLKFIFDC_02764	411469.EUBHAL_01534	1.1e-183	511.0	COG1148@1|root,COG2878@1|root,COG1148@2|Bacteria,COG2878@2|Bacteria,1TQGD@1239|Firmicutes,24904@186801|Clostridia,25VDB@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	rnfB	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4,Fer4_13,Fer4_4,Fer4_9
HLKFIFDC_02765	411469.EUBHAL_01535	7.22e-239	655.0	COG2267@1|root,COG2267@2|Bacteria,1TRM1@1239|Firmicutes,247J5@186801|Clostridia,25UU9@186806|Eubacteriaceae	186801|Clostridia	I	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4,Peptidase_S9
HLKFIFDC_02766	411469.EUBHAL_01536	4.61e-57	176.0	COG1873@1|root,COG1873@2|Bacteria	2|Bacteria	S	PRC-barrel domain	ylmC	-	-	-	-	-	-	-	-	-	-	-	PRC
HLKFIFDC_02767	411469.EUBHAL_01537	8.12e-104	300.0	COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,24HFT@186801|Clostridia,25WGV@186806|Eubacteriaceae	186801|Clostridia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
HLKFIFDC_02768	411469.EUBHAL_01468	0.0	1050.0	COG0606@1|root,COG0606@2|Bacteria,1TPPB@1239|Firmicutes,248T8@186801|Clostridia,25URN@186806|Eubacteriaceae	186801|Clostridia	O	Mg chelatase-like protein	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
HLKFIFDC_02769	411469.EUBHAL_01469	2.09e-266	729.0	COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,24AS2@186801|Clostridia,25VKT@186806|Eubacteriaceae	186801|Clostridia	LU	DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
HLKFIFDC_02770	411469.EUBHAL_01470	0.0	1362.0	COG0550@1|root,COG0550@2|Bacteria,1TPUS@1239|Firmicutes,248MG@186801|Clostridia,25V5P@186806|Eubacteriaceae	186801|Clostridia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
HLKFIFDC_02771	411469.EUBHAL_01471	1.41e-172	483.0	COG4465@1|root,COG4465@2|Bacteria,1TS7A@1239|Firmicutes,2480R@186801|Clostridia,25VC1@186806|Eubacteriaceae	186801|Clostridia	K	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor	codY	-	-	ko:K03706	-	-	-	-	ko00000,ko03000	-	-	-	CodY,HTH_CodY
HLKFIFDC_02772	411469.EUBHAL_01472	0.0	1163.0	COG1479@1|root,COG3472@1|root,COG1479@2|Bacteria,COG3472@2|Bacteria,1TQ81@1239|Firmicutes,24BX6@186801|Clostridia,25XTX@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function DUF262	-	-	-	-	-	-	-	-	-	-	-	-	DUF262
HLKFIFDC_02773	411469.EUBHAL_01473	1.12e-169	475.0	COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,25UT8@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
HLKFIFDC_02774	411469.EUBHAL_01474	6.37e-207	574.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,25V66@186806|Eubacteriaceae	186801|Clostridia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
HLKFIFDC_02776	411469.EUBHAL_01487	0.0	1897.0	COG4733@1|root,COG4733@2|Bacteria,1VDKU@1239|Firmicutes,24PKK@186801|Clostridia,25XFG@186806|Eubacteriaceae	186801|Clostridia	M	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02777	411469.EUBHAL_01488	3.53e-158	444.0	COG1309@1|root,COG1309@2|Bacteria,1VJYD@1239|Firmicutes,24SNN@186801|Clostridia	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HLKFIFDC_02779	411469.EUBHAL_01490	1.69e-183	521.0	COG0790@1|root,COG0790@2|Bacteria,1TS5X@1239|Firmicutes,248TS@186801|Clostridia,25XQ9@186806|Eubacteriaceae	186801|Clostridia	S	Sel1-like repeats.	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1,TPR_16,TPR_7,TPR_8
HLKFIFDC_02780	411469.EUBHAL_02149	3.63e-55	174.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia,25VBA@186806|Eubacteriaceae	186801|Clostridia	L	Probable transposase	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
HLKFIFDC_02781	411469.EUBHAL_00707	4.18e-122	352.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia,25VBA@186806|Eubacteriaceae	186801|Clostridia	L	Probable transposase	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
HLKFIFDC_02782	411469.EUBHAL_03144	0.0	1306.0	COG0369@1|root,COG1151@2|Bacteria,1TRSC@1239|Firmicutes,248HQ@186801|Clostridia,25UUE@186806|Eubacteriaceae	186801|Clostridia	C	Carbon-monoxide dehydrogenase, catalytic subunit	cooS	-	1.2.7.4	ko:K00198	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	M00377	R07157,R08034	RC00250,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Prismane
HLKFIFDC_02783	411469.EUBHAL_03145	0.0	878.0	COG3383@1|root,COG4624@1|root,COG3383@2|Bacteria,COG4624@2|Bacteria,1TP6C@1239|Firmicutes,25E8M@186801|Clostridia,25ZQA@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer4,Rubrerythrin
HLKFIFDC_02784	411469.EUBHAL_03146	1.09e-20	84.0	2C9RV@1|root,32WXH@2|Bacteria,1VCZ0@1239|Firmicutes,24NC4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02785	411461.DORFOR_00166	1.06e-75	228.0	COG1225@1|root,COG1225@2|Bacteria,1V3N5@1239|Firmicutes,24HP8@186801|Clostridia,27WBZ@189330|Dorea	186801|Clostridia	O	Redoxin	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
HLKFIFDC_02786	1256908.HMPREF0373_00075	2.67e-16	73.6	COG1225@1|root,COG1225@2|Bacteria,1V3N5@1239|Firmicutes,24HP8@186801|Clostridia,25WN0@186806|Eubacteriaceae	186801|Clostridia	O	Antioxidant, AhpC TSA family	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
HLKFIFDC_02787	411469.EUBHAL_03148	6.62e-178	495.0	COG3022@1|root,COG3022@2|Bacteria,1TR33@1239|Firmicutes,248N1@186801|Clostridia,25VSE@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the UPF0246 family	-	-	-	ko:K09861	-	-	-	-	ko00000	-	-	-	H2O2_YaaD
HLKFIFDC_02788	411469.EUBHAL_03150	2.51e-155	436.0	COG1773@1|root,COG1853@1|root,COG1773@2|Bacteria,COG1853@2|Bacteria,1UIB1@1239|Firmicutes,25EG4@186801|Clostridia	186801|Clostridia	C	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
HLKFIFDC_02789	411469.EUBHAL_03151	7.9e-128	363.0	COG1592@1|root,COG1592@2|Bacteria,1V1FF@1239|Firmicutes,248V2@186801|Clostridia,25W6N@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	rbr	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct,Rubrerythrin
HLKFIFDC_02790	411469.EUBHAL_03152	5.5e-93	270.0	COG2033@1|root,COG2033@2|Bacteria,1VA34@1239|Firmicutes,24J9I@186801|Clostridia,25WZB@186806|Eubacteriaceae	186801|Clostridia	C	superoxide reductase	-	-	1.15.1.2	ko:K05919	-	-	-	-	ko00000,ko01000	-	-	-	Desulfoferrod_N,Desulfoferrodox
HLKFIFDC_02791	411459.RUMOBE_03494	2.76e-165	463.0	COG1028@1|root,COG1028@2|Bacteria,1TPIK@1239|Firmicutes,25073@186801|Clostridia,3XYII@572511|Blautia	186801|Clostridia	IQ	Psort location Cytoplasmic, score	baiA	-	1.1.1.100,1.1.1.159	ko:K00059,ko:K00076	ko00061,ko00121,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00121,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
HLKFIFDC_02792	411459.RUMOBE_03495	2.05e-66	201.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,3Y0FX@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
HLKFIFDC_02793	411469.EUBHAL_00729	4.54e-70	211.0	COG0607@1|root,COG0607@2|Bacteria,1U0PW@1239|Firmicutes,24RKU@186801|Clostridia,25WWW@186806|Eubacteriaceae	186801|Clostridia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
HLKFIFDC_02794	411459.RUMOBE_03497	0.0	1105.0	COG0446@1|root,COG0607@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,1TPWW@1239|Firmicutes,2484C@186801|Clostridia,3XZ97@572511|Blautia	186801|Clostridia	P	Psort location Cytoplasmic, score 9.98	cdr	-	-	-	-	-	-	-	-	-	-	-	DrsE_2,Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA
HLKFIFDC_02795	411469.EUBHAL_00731	3.29e-154	433.0	COG0664@1|root,COG0664@2|Bacteria,1V2MV@1239|Firmicutes,24B7K@186801|Clostridia,25WMM@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
HLKFIFDC_02796	411469.EUBHAL_00737	6.8e-190	527.0	COG3649@1|root,COG3649@2|Bacteria,1TQZ8@1239|Firmicutes,248MT@186801|Clostridia,25UYH@186806|Eubacteriaceae	186801|Clostridia	L	CRISPR-associated protein Cas7	-	-	-	ko:K19115,ko:K19118	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Cas7
HLKFIFDC_02797	411469.EUBHAL_00740	7.33e-60	186.0	COG3316@1|root,COG3316@2|Bacteria,1UK6Y@1239|Firmicutes,24RFW@186801|Clostridia	186801|Clostridia	L	IS66 C-terminal element	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C
HLKFIFDC_02798	411469.EUBHAL_00741	3e-88	260.0	COG1595@1|root,COG1595@2|Bacteria,1V22M@1239|Firmicutes,24EDG@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4,Sigma70_r4_2
HLKFIFDC_02799	411469.EUBHAL_00742	6.09e-09	53.1	2AJW5@1|root,32RUV@2|Bacteria,1VA55@1239|Firmicutes,25E1F@186801|Clostridia	186801|Clostridia	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_16
HLKFIFDC_02800	478749.BRYFOR_09542	1.01e-37	129.0	2CFWV@1|root,32S2P@2|Bacteria,1VB1F@1239|Firmicutes,24PZR@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02801	264731.PRU_1733	1.76e-19	81.3	2ENSY@1|root,33GE3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02802	869209.Tresu_0953	1.4e-40	135.0	2DICR@1|root,302SH@2|Bacteria,2J8H7@203691|Spirochaetes	203691|Spirochaetes	S	Domain of unknown function (DUF4160)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
HLKFIFDC_02803	638302.HMPREF0908_1961	3.25e-34	120.0	2DZYH@1|root,32VN8@2|Bacteria,1VB55@1239|Firmicutes	1239|Firmicutes	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
HLKFIFDC_02804	411469.EUBHAL_01558	8.48e-16	71.2	COG4636@1|root,COG4636@2|Bacteria,1U4F6@1239|Firmicutes,259DJ@186801|Clostridia,25YVU@186806|Eubacteriaceae	186801|Clostridia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
HLKFIFDC_02805	411469.EUBHAL_00397	0.0	1440.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,25V53@186806|Eubacteriaceae	186801|Clostridia	T	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg
HLKFIFDC_02806	411469.EUBHAL_00399	0.0	1109.0	COG1653@1|root,COG1653@2|Bacteria,1VE90@1239|Firmicutes,24Q7Y@186801|Clostridia	186801|Clostridia	G	transport	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02807	411459.RUMOBE_02565	0.0	1110.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,3XZ5S@572511|Blautia	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg
HLKFIFDC_02808	411469.EUBHAL_03114	9.18e-53	165.0	2EDSQ@1|root,337N4@2|Bacteria,1VFPQ@1239|Firmicutes,24SX6@186801|Clostridia,25Z99@186806|Eubacteriaceae	186801|Clostridia	S	Restriction alleviation protein Lar	-	-	-	-	-	-	-	-	-	-	-	-	Lar_restr_allev
HLKFIFDC_02812	411469.EUBHAL_03110	0.0	1221.0	COG0642@1|root,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,25UR7@186806|Eubacteriaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HD,HisKA,Hpt,MASE3,Response_reg
HLKFIFDC_02813	411469.EUBHAL_01793	7.54e-107	312.0	COG2197@1|root,COG2197@2|Bacteria,1UQ9Y@1239|Firmicutes,24EZU@186801|Clostridia	186801|Clostridia	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
HLKFIFDC_02814	411469.EUBHAL_01794	1.51e-154	437.0	COG0561@1|root,COG0561@2|Bacteria,1TSZZ@1239|Firmicutes,24B3M@186801|Clostridia,25XGP@186806|Eubacteriaceae	186801|Clostridia	S	Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
HLKFIFDC_02815	1280682.AUKA01000017_gene544	1.52e-20	86.3	COG2452@1|root,COG2452@2|Bacteria,1UZ1U@1239|Firmicutes,24F52@186801|Clostridia,4BYPI@830|Butyrivibrio	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR_1,Resolvase
HLKFIFDC_02816	511680.BUTYVIB_02470	8.49e-238	658.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia,4BYA5@830|Butyrivibrio	186801|Clostridia	L	Putative transposase DNA-binding domain	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
HLKFIFDC_02817	411469.EUBHAL_01795	1.57e-187	521.0	COG0561@1|root,COG0561@2|Bacteria,1V43V@1239|Firmicutes,24AQQ@186801|Clostridia,25X0W@186806|Eubacteriaceae	186801|Clostridia	S	Sucrose-6F-phosphate phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
HLKFIFDC_02818	411469.EUBHAL_01796	3.28e-165	462.0	COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,248Z6@186801|Clostridia,25V4X@186806|Eubacteriaceae	186801|Clostridia	V	ABC-type antimicrobial peptide transport system, ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HLKFIFDC_02819	411469.EUBHAL_01797	0.0	1461.0	COG0577@1|root,COG0577@2|Bacteria,1TPHU@1239|Firmicutes,247QW@186801|Clostridia,25VGB@186806|Eubacteriaceae	186801|Clostridia	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
HLKFIFDC_02820	585394.RHOM_00340	3.42e-13	67.8	COG4302@1|root,COG4302@2|Bacteria,1TSZM@1239|Firmicutes,24A5Y@186801|Clostridia	186801|Clostridia	E	Belongs to the EutC family	eutC	-	4.3.1.7	ko:K03736	ko00564,ko01100,map00564,map01100	-	R00749	RC00370	ko00000,ko00001,ko01000	-	-	-	EutC
HLKFIFDC_02821	411469.EUBHAL_01236	2.51e-42	163.0	2BY06@1|root,32UQI@2|Bacteria,1VDT6@1239|Firmicutes,24V83@186801|Clostridia,25YQ3@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02822	411469.EUBHAL_01235	9.69e-128	363.0	COG1595@1|root,COG1595@2|Bacteria,1UVHN@1239|Firmicutes,25MUX@186801|Clostridia,25YM2@186806|Eubacteriaceae	186801|Clostridia	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HLKFIFDC_02823	411469.EUBHAL_01236	0.0	933.0	2BY06@1|root,32UQI@2|Bacteria,1VDT6@1239|Firmicutes,24V83@186801|Clostridia,25YQ3@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02824	411469.EUBHAL_01237	1.6e-40	134.0	2EIYR@1|root,33CPX@2|Bacteria,1VMV7@1239|Firmicutes,24VGC@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	FeoA
HLKFIFDC_02825	411469.EUBHAL_01238	1.58e-213	593.0	COG1284@1|root,COG1284@2|Bacteria,1TRBT@1239|Firmicutes,248B1@186801|Clostridia,25ZF8@186806|Eubacteriaceae	186801|Clostridia	S	CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
HLKFIFDC_02826	411469.EUBHAL_02854	2.78e-311	848.0	COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,25UVC@186806|Eubacteriaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
HLKFIFDC_02827	411469.EUBHAL_02855	1.66e-217	600.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,2497G@186801|Clostridia,25UVD@186806|Eubacteriaceae	186801|Clostridia	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
HLKFIFDC_02828	411469.EUBHAL_02857	2.38e-76	227.0	2BW9N@1|root,32QZ7@2|Bacteria,1V8SR@1239|Firmicutes,24KPI@186801|Clostridia,25Z72@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02829	411469.EUBHAL_01616	4.61e-141	397.0	COG5423@1|root,COG5423@2|Bacteria,1V8BX@1239|Firmicutes,24JN8@186801|Clostridia,25WSV@186806|Eubacteriaceae	186801|Clostridia	S	Predicted metal-binding protein (DUF2284)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2284
HLKFIFDC_02830	632245.CLP_0435	2.05e-119	348.0	COG1434@1|root,COG1434@2|Bacteria,1TS1Q@1239|Firmicutes,24B02@186801|Clostridia,36DHE@31979|Clostridiaceae	186801|Clostridia	S	Gram-negative-bacterium-type cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
HLKFIFDC_02831	457412.RSAG_03147	1.48e-56	186.0	COG5464@1|root,COG5464@2|Bacteria,1TYQI@1239|Firmicutes,24FIE@186801|Clostridia,3WRZY@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_31
HLKFIFDC_02832	457412.RSAG_03152	2.43e-14	72.0	COG1672@1|root,COG1672@2|Bacteria,1TQQ5@1239|Firmicutes,24918@186801|Clostridia,3WH77@541000|Ruminococcaceae	186801|Clostridia	S	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
HLKFIFDC_02833	411469.EUBHAL_01618	9.88e-152	426.0	COG2755@1|root,COG2755@2|Bacteria,1U5WX@1239|Firmicutes,25BIZ@186801|Clostridia,25WE4@186806|Eubacteriaceae	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
HLKFIFDC_02835	411469.EUBHAL_01620	7.83e-205	566.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1VK50@1239|Firmicutes,25BJ0@186801|Clostridia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	-	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2
HLKFIFDC_02837	411469.EUBHAL_01622	0.0	878.0	COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,25UVC@186806|Eubacteriaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
HLKFIFDC_02838	411469.EUBHAL_01623	4.93e-234	645.0	COG1705@1|root,COG1705@2|Bacteria,1V7JY@1239|Firmicutes,24C0T@186801|Clostridia,25ZAN@186806|Eubacteriaceae	186801|Clostridia	NU	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,Amidase_3,CW_7,CW_binding_1,Cu_amine_oxidN1,Glucosaminidase,PG_binding_1
HLKFIFDC_02839	411469.EUBHAL_01624	3.3e-80	239.0	2E06E@1|root,32VUE@2|Bacteria,1VCMY@1239|Firmicutes,24NKQ@186801|Clostridia,25YVK@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02840	411469.EUBHAL_01626	1.14e-157	442.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,2484X@186801|Clostridia,25UU1@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	srrA_6	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HLKFIFDC_02841	411469.EUBHAL_01627	0.0	987.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,25UVP@186806|Eubacteriaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
HLKFIFDC_02842	411469.EUBHAL_02201	6.9e-298	812.0	COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,25V8H@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
HLKFIFDC_02843	411469.EUBHAL_02200	0.0	893.0	COG1323@1|root,COG1323@2|Bacteria,1TPP2@1239|Firmicutes,247UP@186801|Clostridia,25V00@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the UPF0348 family	-	-	-	-	-	-	-	-	-	-	-	-	HIGH_NTase1
HLKFIFDC_02844	411469.EUBHAL_02198	1.03e-202	561.0	COG4667@1|root,COG4667@2|Bacteria,1TQ9W@1239|Firmicutes,2485C@186801|Clostridia,25VW9@186806|Eubacteriaceae	186801|Clostridia	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
HLKFIFDC_02845	411469.EUBHAL_02197	2.75e-216	597.0	COG0549@1|root,COG0549@2|Bacteria,1TP9H@1239|Firmicutes,2482W@186801|Clostridia,25V49@186806|Eubacteriaceae	186801|Clostridia	E	carbamate kinase	arcC	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
HLKFIFDC_02846	457396.CSBG_03326	3.77e-09	58.9	COG5566@1|root,COG5566@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Mor
HLKFIFDC_02847	1123263.AUKY01000003_gene276	1.99e-45	150.0	COG1396@1|root,COG1396@2|Bacteria,1VGAT@1239|Firmicutes,3VS4H@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HLKFIFDC_02848	1408323.JQKK01000022_gene3232	4.29e-132	385.0	COG2378@1|root,COG2378@2|Bacteria,1TWXW@1239|Firmicutes,247QJ@186801|Clostridia,27IU9@186928|unclassified Lachnospiraceae	186801|Clostridia	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
HLKFIFDC_02852	575593.HMPREF0491_02856	2.28e-44	171.0	COG0790@1|root,COG0790@2|Bacteria,1TS5X@1239|Firmicutes,248TS@186801|Clostridia,27N8B@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Sel1-like repeats.	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1,TPR_16,TPR_7,TPR_8
HLKFIFDC_02853	1410628.JNKS01000002_gene3075	0.0	1109.0	COG0433@1|root,COG0433@2|Bacteria,1TQPR@1239|Firmicutes,249UU@186801|Clostridia,27J8W@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Domain of unknown function DUF87	-	-	-	-	-	-	-	-	-	-	-	-	DUF87
HLKFIFDC_02854	575593.HMPREF0491_01637	1.55e-69	220.0	COG5444@1|root,COG5444@2|Bacteria,1V6QC@1239|Firmicutes,24SZ6@186801|Clostridia	186801|Clostridia	S	DNA/RNA non-specific endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclea_NS_2
HLKFIFDC_02856	411469.EUBHAL_02187	2.28e-129	374.0	COG5464@1|root,COG5464@2|Bacteria,1TS6U@1239|Firmicutes,24A2X@186801|Clostridia,25WK9@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
HLKFIFDC_02857	411469.EUBHAL_02193	4.13e-314	855.0	COG4733@1|root,COG5279@1|root,COG4733@2|Bacteria,COG5279@2|Bacteria,1V2RG@1239|Firmicutes,24GD8@186801|Clostridia	186801|Clostridia	D	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
HLKFIFDC_02858	411469.EUBHAL_02192	1.5e-65	202.0	COG5464@1|root,COG5464@2|Bacteria,1UA0N@1239|Firmicutes,247X9@186801|Clostridia,25WKX@186806|Eubacteriaceae	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
HLKFIFDC_02859	411469.EUBHAL_02192	4.98e-17	76.3	COG5464@1|root,COG5464@2|Bacteria,1UA0N@1239|Firmicutes,247X9@186801|Clostridia,25WKX@186806|Eubacteriaceae	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
HLKFIFDC_02862	411469.EUBHAL_02187	4.79e-223	617.0	COG5464@1|root,COG5464@2|Bacteria,1TS6U@1239|Firmicutes,24A2X@186801|Clostridia,25WK9@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
HLKFIFDC_02863	411469.EUBHAL_02186	5.01e-171	478.0	COG1583@1|root,COG1583@2|Bacteria,1VC7U@1239|Firmicutes,24CJS@186801|Clostridia,25YMK@186806|Eubacteriaceae	186801|Clostridia	L	CRISPR associated protein Cas6	cas6	-	-	ko:K19091	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Cas_Cas6
HLKFIFDC_02864	411469.EUBHAL_02185	0.0	891.0	28MWF@1|root,2ZB3P@2|Bacteria,1TS9V@1239|Firmicutes,24E9P@186801|Clostridia,25Y4Z@186806|Eubacteriaceae	186801|Clostridia	S	CRISPR-associated protein Csx8 (Cas_Csx8)	csx8	-	-	ko:K19088	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Csx8
HLKFIFDC_02865	411469.EUBHAL_02184	8.49e-211	583.0	COG1857@1|root,COG1857@2|Bacteria,1TRGS@1239|Firmicutes,24CU1@186801|Clostridia,25YC9@186806|Eubacteriaceae	186801|Clostridia	L	CRISPR-associated negative auto-regulator DevR/Csa2	cst2	-	-	ko:K19075	-	-	-	-	ko00000,ko02048	-	-	-	DevR
HLKFIFDC_02866	411469.EUBHAL_02183	6.63e-258	707.0	COG1688@1|root,COG1688@2|Bacteria,1UYJD@1239|Firmicutes,24BJA@186801|Clostridia,25Y8R@186806|Eubacteriaceae	186801|Clostridia	L	CRISPR-associated protein Cas5	cas5	-	-	ko:K19090	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Cas5d
HLKFIFDC_02867	411469.EUBHAL_02182	0.0	1269.0	COG1203@1|root,COG1203@2|Bacteria,1TQ9B@1239|Firmicutes,248UE@186801|Clostridia,25W5E@186806|Eubacteriaceae	186801|Clostridia	L	DEAD-like helicases superfamily	cas3	-	-	ko:K07012	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DEAD,HD,Helicase_C
HLKFIFDC_02868	622312.ROSEINA2194_02519	3.34e-11	62.8	COG1672@1|root,COG1672@2|Bacteria,1TQQ5@1239|Firmicutes,24918@186801|Clostridia	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
HLKFIFDC_02869	411469.EUBHAL_02178	2.74e-85	254.0	COG1595@1|root,COG1595@2|Bacteria,1V8A6@1239|Firmicutes,24CUW@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
HLKFIFDC_02870	411469.EUBHAL_02176	1.96e-75	226.0	2EBCY@1|root,335DN@2|Bacteria,1VF9P@1239|Firmicutes,24KM6@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02871	411469.EUBHAL_02175	3.43e-141	399.0	2D2WM@1|root,32TDR@2|Bacteria,1VCUC@1239|Firmicutes,24GMH@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02872	411469.EUBHAL_02174	4.87e-148	417.0	COG2339@1|root,COG2339@2|Bacteria,1V3JI@1239|Firmicutes,24AZQ@186801|Clostridia,25Z06@186806|Eubacteriaceae	186801|Clostridia	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
HLKFIFDC_02874	411469.EUBHAL_02172	0.0	3370.0	COG3210@1|root,COG5492@1|root,COG3210@2|Bacteria,COG5492@2|Bacteria,1UK4Y@1239|Firmicutes,25FK7@186801|Clostridia,25XVC@186806|Eubacteriaceae	186801|Clostridia	U	Leucine rich repeats (6 copies)	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
HLKFIFDC_02875	411469.EUBHAL_02171	0.0	1046.0	2BW99@1|root,2Z7PD@2|Bacteria,1TQFA@1239|Firmicutes,249NB@186801|Clostridia,25UX7@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02876	411469.EUBHAL_00972	0.0	1301.0	COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia,25UXD@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
HLKFIFDC_02877	411469.EUBHAL_02038	0.0	1002.0	COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,248G1@186801|Clostridia,25UT1@186806|Eubacteriaceae	186801|Clostridia	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
HLKFIFDC_02878	411469.EUBHAL_02037	6.64e-259	709.0	COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,24837@186801|Clostridia,25UYK@186806|Eubacteriaceae	186801|Clostridia	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
HLKFIFDC_02879	411469.EUBHAL_02036	2.65e-246	677.0	COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,248CN@186801|Clostridia,25V56@186806|Eubacteriaceae	186801|Clostridia	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
HLKFIFDC_02880	411469.EUBHAL_02035	4.06e-212	586.0	COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,24838@186801|Clostridia,25W1H@186806|Eubacteriaceae	186801|Clostridia	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
HLKFIFDC_02881	411469.EUBHAL_02034	2.7e-216	598.0	COG3872@1|root,COG3872@2|Bacteria,1TPBU@1239|Firmicutes,25C8E@186801|Clostridia,25URQ@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF1385)	prmC	-	-	-	-	-	-	-	-	-	-	-	DUF1385,MTS
HLKFIFDC_02882	411469.EUBHAL_02033	8.41e-46	147.0	COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,24QNZ@186801|Clostridia,25X15@186806|Eubacteriaceae	186801|Clostridia	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
HLKFIFDC_02883	411469.EUBHAL_02032	1.17e-155	438.0	2DMUC@1|root,32TQR@2|Bacteria,1V9Y3@1239|Firmicutes,24QZE@186801|Clostridia,25X8E@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	CpXC
HLKFIFDC_02884	411469.EUBHAL_02031	0.0	5936.0	COG4447@1|root,COG4733@1|root,COG4447@2|Bacteria,COG4733@2|Bacteria,1VMHH@1239|Firmicutes,25KIJ@186801|Clostridia,25YV0@186806|Eubacteriaceae	186801|Clostridia	D	Immunoglobulin	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02885	411469.EUBHAL_02029	1.75e-122	351.0	COG1268@1|root,COG1268@2|Bacteria,1VAY6@1239|Firmicutes,24HPU@186801|Clostridia,25WKC@186806|Eubacteriaceae	186801|Clostridia	S	BioY family	bioY	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
HLKFIFDC_02886	411469.EUBHAL_02028	0.0	1239.0	COG0493@1|root,COG1894@1|root,COG0493@2|Bacteria,COG1894@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,25UR0@186806|Eubacteriaceae	186801|Clostridia	C	NADPH-dependent glutamate synthase beta chain and related oxidoreductases	sfrB	-	1.17.1.10	ko:K15022	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00377	R00134	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,NADH_4Fe-4S,Pyr_redox_2
HLKFIFDC_02887	411469.EUBHAL_02027	0.0	1199.0	COG3383@1|root,COG4624@1|root,COG3383@2|Bacteria,COG4624@2|Bacteria,1TP6C@1239|Firmicutes,24897@186801|Clostridia,25VMH@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	hydC	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_7,NADH-G_4Fe-4S_3
HLKFIFDC_02888	411469.EUBHAL_02026	3.64e-174	489.0	28IBJ@1|root,2Z8XY@2|Bacteria,1UCWW@1239|Firmicutes,24DUG@186801|Clostridia,25V2V@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02889	411469.EUBHAL_02025	8.08e-144	407.0	COG0546@1|root,COG0546@2|Bacteria,1TPPZ@1239|Firmicutes,24GK6@186801|Clostridia,25W2G@186806|Eubacteriaceae	186801|Clostridia	S	HAD-hyrolase-like	ppaX	-	3.1.3.18,3.6.1.1	ko:K01091,ko:K06019	ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
HLKFIFDC_02890	411469.EUBHAL_02024	2.78e-315	858.0	COG0176@1|root,COG0176@2|Bacteria,1UYMX@1239|Firmicutes,249D1@186801|Clostridia,25V8E@186806|Eubacteriaceae	186801|Clostridia	G	Pfam:Transaldolase	-	-	-	-	-	-	-	-	-	-	-	-	TAL_FSA
HLKFIFDC_02891	411469.EUBHAL_02023	9.01e-276	754.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,25V1F@186806|Eubacteriaceae	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	3.6.3.20	ko:K05816,ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00198,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1,3.A.1.1.3	-	-	ABC_tran,TOBE,TOBE_2
HLKFIFDC_02892	411469.EUBHAL_02022	0.0	889.0	COG1653@1|root,COG1653@2|Bacteria,1TQHT@1239|Firmicutes,249J6@186801|Clostridia,25VT8@186806|Eubacteriaceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	amyE	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_8,TAT_signal
HLKFIFDC_02893	411469.EUBHAL_02021	7.77e-197	546.0	COG1175@1|root,COG1175@2|Bacteria,1TP1Q@1239|Firmicutes,24ADV@186801|Clostridia,25UYX@186806|Eubacteriaceae	186801|Clostridia	P	permease	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
HLKFIFDC_02894	411469.EUBHAL_02020	6.61e-192	533.0	COG0395@1|root,COG0395@2|Bacteria,1TR45@1239|Firmicutes,24A48@186801|Clostridia,25UYF@186806|Eubacteriaceae	186801|Clostridia	P	sugar transport system permease	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
HLKFIFDC_02895	411469.EUBHAL_02019	3.77e-245	673.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,25WGG@186806|Eubacteriaceae	186801|Clostridia	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
HLKFIFDC_02896	411469.EUBHAL_02018	0.0	1036.0	COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia,25UZT@186806|Eubacteriaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
HLKFIFDC_02897	1121115.AXVN01000003_gene1579	1.59e-59	184.0	COG1694@1|root,COG1694@2|Bacteria,1VA3E@1239|Firmicutes,24NYY@186801|Clostridia,3Y09V@572511|Blautia	186801|Clostridia	S	MazG-like family	-	-	-	-	-	-	-	-	-	-	-	-	MazG-like
HLKFIFDC_02898	556261.HMPREF0240_02220	1.23e-304	844.0	COG3410@1|root,COG3410@2|Bacteria,1TPQU@1239|Firmicutes,24BAG@186801|Clostridia,36GIX@31979|Clostridiaceae	186801|Clostridia	L	Uncharacterized conserved protein (DUF2075)	-	-	-	ko:K09384	-	-	-	-	ko00000	-	-	-	DUF2075,GIY-YIG
HLKFIFDC_02899	411469.EUBHAL_01057	2.8e-75	225.0	COG2033@1|root,COG2033@2|Bacteria,1VA34@1239|Firmicutes,24J9I@186801|Clostridia,25WZB@186806|Eubacteriaceae	186801|Clostridia	C	superoxide reductase	dfx	-	1.15.1.2	ko:K05919	-	-	-	-	ko00000,ko01000	-	-	-	Desulfoferrod_N,Desulfoferrodox
HLKFIFDC_02900	1232447.BAHW02000019_gene1208	6.57e-181	507.0	COG3177@1|root,COG3177@2|Bacteria,1TZWX@1239|Firmicutes,247MZ@186801|Clostridia	186801|Clostridia	E	Filamentation induced by cAMP protein fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic
HLKFIFDC_02901	411469.EUBHAL_02016	2.85e-208	575.0	COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia,25UWN@186806|Eubacteriaceae	186801|Clostridia	G	Fructose-1,6-bisphosphate aldolase, class II	fba	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
HLKFIFDC_02902	411469.EUBHAL_02015	1.17e-166	467.0	COG0760@1|root,COG0760@2|Bacteria,1V5Q2@1239|Firmicutes,248JQ@186801|Clostridia,25WK2@186806|Eubacteriaceae	186801|Clostridia	O	PPIC-type PPIASE domain	prsA2	-	5.2.1.8	ko:K03769,ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3
HLKFIFDC_02903	411469.EUBHAL_02014	0.0	1105.0	COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,2481Y@186801|Clostridia,25UZH@186806|Eubacteriaceae	186801|Clostridia	G	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II	pgcA	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
HLKFIFDC_02904	411469.EUBHAL_03086	0.0	1691.0	COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,248EH@186801|Clostridia,25V1V@186806|Eubacteriaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	cadA	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
HLKFIFDC_02905	411469.EUBHAL_03085	1.69e-79	236.0	COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,24JCN@186801|Clostridia,25WU6@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	ziaR	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
HLKFIFDC_02906	411469.EUBHAL_03084	2.49e-236	650.0	COG1237@1|root,COG1237@2|Bacteria,1UWI6@1239|Firmicutes,247K3@186801|Clostridia,25WBE@186806|Eubacteriaceae	186801|Clostridia	S	Metallo-beta-lactamase superfamily	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
HLKFIFDC_02907	411469.EUBHAL_03083	2.13e-256	703.0	COG0469@1|root,COG0469@2|Bacteria,1TQC0@1239|Firmicutes,24CHE@186801|Clostridia,25UVY@186806|Eubacteriaceae	186801|Clostridia	H	HpcH/HpaI aldolase/citrate lyase family	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK
HLKFIFDC_02908	411469.EUBHAL_03082	0.0	1442.0	COG0188@1|root,COG0188@2|Bacteria,1TPNX@1239|Firmicutes,24ADK@186801|Clostridia,25UZD@186806|Eubacteriaceae	186801|Clostridia	L	DNA gyrase	gyrA_1	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
HLKFIFDC_02909	411469.EUBHAL_03081	0.0	1264.0	COG0187@1|root,COG0187@2|Bacteria,1TRSZ@1239|Firmicutes,247ZY@186801|Clostridia,25UT9@186806|Eubacteriaceae	186801|Clostridia	L	DNA gyrase	parE	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
HLKFIFDC_02910	411469.EUBHAL_03080	8.11e-166	462.0	COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,24GJJ@186801|Clostridia,25W8M@186806|Eubacteriaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
HLKFIFDC_02911	411469.EUBHAL_03079	0.0	909.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,25100@186801|Clostridia,25VJN@186806|Eubacteriaceae	186801|Clostridia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HLKFIFDC_02912	411469.EUBHAL_03078	4.9e-303	825.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,2484F@186801|Clostridia,25ZMR@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35,4.2.1.85	ko:K01703,ko:K20452	ko00290,ko00660,ko00760,ko00966,ko01100,ko01110,ko01120,ko01210,ko01230,map00290,map00660,map00760,map00966,map01100,map01110,map01120,map01210,map01230	M00432,M00535	R03069,R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00843,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
HLKFIFDC_02913	411469.EUBHAL_03077	1.37e-114	328.0	COG0066@1|root,COG0066@2|Bacteria,1V1I6@1239|Firmicutes,24FR6@186801|Clostridia,25YEW@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
HLKFIFDC_02914	411469.EUBHAL_03076	1.78e-303	827.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,2484F@186801|Clostridia,25ZMR@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35,4.2.1.85	ko:K01703,ko:K20452	ko00290,ko00660,ko00760,ko00966,ko01100,ko01110,ko01120,ko01210,ko01230,map00290,map00660,map00760,map00966,map01100,map01110,map01120,map01210,map01230	M00432,M00535	R03069,R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00843,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
HLKFIFDC_02915	411469.EUBHAL_03075	2.49e-110	317.0	COG0066@1|root,COG0066@2|Bacteria,1V1I6@1239|Firmicutes,24FUI@186801|Clostridia,25W2J@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35,4.2.1.85	ko:K01704,ko:K20453	ko00290,ko00660,ko00760,ko01100,ko01110,ko01120,ko01210,ko01230,map00290,map00660,map00760,map01100,map01110,map01120,map01210,map01230	M00432,M00535	R03069,R03896,R03898,R03968,R04001,R10170	RC00843,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
HLKFIFDC_02916	411469.EUBHAL_03073	1.36e-34	118.0	2EG1V@1|root,339TV@2|Bacteria,1VKAZ@1239|Firmicutes,24UGV@186801|Clostridia,25XSW@186806|Eubacteriaceae	186801|Clostridia	S	Domain of unknown function (DUF4250)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4250
HLKFIFDC_02917	411469.EUBHAL_03071	3.9e-38	127.0	2EGE3@1|root,33A60@2|Bacteria,1VMF7@1239|Firmicutes,24UMV@186801|Clostridia,25XS9@186806|Eubacteriaceae	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02918	411469.EUBHAL_03069	1.88e-222	613.0	COG0248@1|root,COG0248@2|Bacteria,1TS3I@1239|Firmicutes,248EW@186801|Clostridia,25VIC@186806|Eubacteriaceae	186801|Clostridia	FP	Ppx/GppA phosphatase family	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
HLKFIFDC_02920	411469.EUBHAL_03067	0.0	887.0	COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,2499P@186801|Clostridia,25UTX@186806|Eubacteriaceae	186801|Clostridia	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
HLKFIFDC_02921	411469.EUBHAL_03066	4.37e-284	778.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia,25VNE@186806|Eubacteriaceae	186801|Clostridia	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HLKFIFDC_02922	411469.EUBHAL_03065	0.0	1417.0	COG0845@1|root,COG0845@2|Bacteria,1UZ3U@1239|Firmicutes,24BV7@186801|Clostridia,25WXS@186806|Eubacteriaceae	186801|Clostridia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
HLKFIFDC_02923	411469.EUBHAL_03064	6.8e-177	494.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia,25VJW@186806|Eubacteriaceae	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003,ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,FtsX
HLKFIFDC_02924	411469.EUBHAL_03063	5.62e-220	632.0	COG0845@1|root,COG0845@2|Bacteria,1V046@1239|Firmicutes,24ANJ@186801|Clostridia,25W6W@186806|Eubacteriaceae	186801|Clostridia	M	Efflux transporter, RND family, MFP subunit	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
HLKFIFDC_02925	411469.EUBHAL_03062	0.0	921.0	COG2509@1|root,COG2509@2|Bacteria,1TP9I@1239|Firmicutes,247QM@186801|Clostridia,25UQY@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	FAD_binding_2,HI0933_like,Pyr_redox_2,Thi4
HLKFIFDC_02926	411461.DORFOR_03286	1.35e-285	790.0	COG0591@1|root,COG0591@2|Bacteria,1TPVE@1239|Firmicutes,248NQ@186801|Clostridia,27WIN@189330|Dorea	186801|Clostridia	E	Sodium:solute symporter family	putP	-	-	ko:K03307,ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21,2.A.21.2	-	-	SSF
HLKFIFDC_02927	411469.EUBHAL_03168	0.0	1303.0	COG1368@1|root,COG1368@2|Bacteria,1TQYQ@1239|Firmicutes,25CNS@186801|Clostridia,25VAX@186806|Eubacteriaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
HLKFIFDC_02928	411469.EUBHAL_03167	3.37e-142	407.0	COG4509@1|root,COG4509@2|Bacteria,1V7UG@1239|Firmicutes,24KBR@186801|Clostridia,25WQP@186806|Eubacteriaceae	186801|Clostridia	S	sortase, SrtB family	srtB	-	3.4.22.70	ko:K08600	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
HLKFIFDC_02929	411469.EUBHAL_03166	2.1e-122	350.0	COG2087@1|root,COG2087@2|Bacteria,1V6F8@1239|Firmicutes,24JF6@186801|Clostridia,25WWS@186806|Eubacteriaceae	186801|Clostridia	H	Adenosylcobinamide kinase adenosylcobinamide-phosphate guanylyltransferase	cobU	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU
HLKFIFDC_02930	411469.EUBHAL_03165	8.88e-177	494.0	2E4FW@1|root,32ZB1@2|Bacteria,1VES0@1239|Firmicutes,24TIF@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF1189)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1189
HLKFIFDC_02931	411469.EUBHAL_03164	8.3e-123	350.0	COG0693@1|root,COG0693@2|Bacteria,1V3WB@1239|Firmicutes,24HGU@186801|Clostridia,25WM7@186806|Eubacteriaceae	186801|Clostridia	S	DJ-1 family	yajL	-	3.5.1.124	ko:K03152	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
HLKFIFDC_02932	411469.EUBHAL_03163	1.12e-108	313.0	COG2954@1|root,COG2954@2|Bacteria,1V7MS@1239|Firmicutes,24JER@186801|Clostridia,25WPY@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	CYTH
HLKFIFDC_02933	411469.EUBHAL_03162	3.84e-314	860.0	COG1376@1|root,COG1376@2|Bacteria,1TQMA@1239|Firmicutes,248H0@186801|Clostridia,25VRN@186806|Eubacteriaceae	186801|Clostridia	M	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
HLKFIFDC_02934	411469.EUBHAL_03295	4.58e-94	274.0	COG4416@1|root,COG4416@2|Bacteria,1VEMD@1239|Firmicutes,24MRR@186801|Clostridia,25WVJ@186806|Eubacteriaceae	186801|Clostridia	S	COG NOG18757 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02935	411469.EUBHAL_03294	9.55e-101	293.0	COG2426@1|root,COG2426@2|Bacteria,1V3UW@1239|Firmicutes,24HSW@186801|Clostridia,25WA3@186806|Eubacteriaceae	186801|Clostridia	S	small multi-drug export protein	-	-	-	-	-	-	-	-	-	-	-	-	Sm_multidrug_ex
HLKFIFDC_02936	411469.EUBHAL_03293	0.0	874.0	COG1158@1|root,COG1158@2|Bacteria,1TPHZ@1239|Firmicutes,247YK@186801|Clostridia,25V0W@186806|Eubacteriaceae	186801|Clostridia	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
HLKFIFDC_02937	411469.EUBHAL_03292	3.81e-274	750.0	COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,2487U@186801|Clostridia,25UR3@186806|Eubacteriaceae	186801|Clostridia	C	malic enzyme	maeB	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
HLKFIFDC_02938	411469.EUBHAL_03291	1.22e-222	613.0	COG1242@1|root,COG1242@2|Bacteria,1TQ57@1239|Firmicutes,247U3@186801|Clostridia,25V7W@186806|Eubacteriaceae	186801|Clostridia	S	radical SAM protein, TIGR01212 family	ytqA	-	-	ko:K07139	-	-	-	-	ko00000	-	-	-	Radical_SAM,Radical_SAM_C
HLKFIFDC_02939	411469.EUBHAL_03290	2.4e-119	341.0	COG3432@1|root,COG3432@2|Bacteria,1V75P@1239|Firmicutes,24JAZ@186801|Clostridia,25X0E@186806|Eubacteriaceae	186801|Clostridia	K	Domain of unknown function (DUF4364)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4364
HLKFIFDC_02940	411469.EUBHAL_03289	0.0	949.0	COG1142@1|root,COG4624@1|root,COG1142@2|Bacteria,COG4624@2|Bacteria,1TQIR@1239|Firmicutes,248BS@186801|Clostridia,25VE9@186806|Eubacteriaceae	186801|Clostridia	C	4Fe-4S binding domain protein	-	-	1.12.7.2	ko:K00533	-	-	R00019	-	ko00000,ko01000	-	-	-	Fe_hyd_lg_C,Fer4,Fer4_6
HLKFIFDC_02941	411469.EUBHAL_03288	4.28e-313	853.0	COG1167@1|root,COG1167@2|Bacteria,1TPMY@1239|Firmicutes,24986@186801|Clostridia,25URH@186806|Eubacteriaceae	186801|Clostridia	EK	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_MocR
HLKFIFDC_02943	411469.EUBHAL_03283	1.97e-124	355.0	2EACE@1|root,334GC@2|Bacteria,1VJGH@1239|Firmicutes,24T7Y@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02947	411469.EUBHAL_03279	3.06e-303	825.0	COG0515@1|root,COG0515@2|Bacteria,1W0HH@1239|Firmicutes,252VD@186801|Clostridia	186801|Clostridia	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
HLKFIFDC_02948	411469.EUBHAL_03278	1.87e-197	549.0	COG0631@1|root,COG0631@2|Bacteria	2|Bacteria	T	protein serine/threonine phosphatase activity	stp	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
HLKFIFDC_02950	411469.EUBHAL_03276	2.26e-286	782.0	COG0768@1|root,COG0768@2|Bacteria,1TPER@1239|Firmicutes,2486R@186801|Clostridia,25VFC@186806|Eubacteriaceae	186801|Clostridia	M	Penicillin-binding protein, transpeptidase domain protein	ftsI	-	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
HLKFIFDC_02951	411469.EUBHAL_03275	0.0	1004.0	COG0772@1|root,COG0772@2|Bacteria,1UISM@1239|Firmicutes,250R6@186801|Clostridia	186801|Clostridia	D	Cell cycle protein	-	-	-	-	-	-	-	-	-	-	-	-	FTSW_RODA_SPOVE
HLKFIFDC_02952	411469.EUBHAL_03274	1.39e-172	486.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	FHA
HLKFIFDC_02953	411469.EUBHAL_03273	0.0	1048.0	2CSF7@1|root,32SR4@2|Bacteria,1VBPZ@1239|Firmicutes,24NZR@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02955	411469.EUBHAL_03271	0.0	949.0	2DU4N@1|root,33NXD@2|Bacteria,1VNU8@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02957	411469.EUBHAL_03269	1e-221	612.0	COG2207@1|root,COG2207@2|Bacteria,1UYFM@1239|Firmicutes,247WN@186801|Clostridia,25XXS@186806|Eubacteriaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
HLKFIFDC_02958	411469.EUBHAL_03268	9.37e-227	624.0	COG1209@1|root,COG1209@2|Bacteria,1TPR2@1239|Firmicutes,2490F@186801|Clostridia,25VAK@186806|Eubacteriaceae	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
HLKFIFDC_02959	411469.EUBHAL_03267	8.75e-166	466.0	COG2207@1|root,COG2207@2|Bacteria,1TQ2W@1239|Firmicutes,24A5W@186801|Clostridia,25XKS@186806|Eubacteriaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18,HTH_AraC
HLKFIFDC_02960	411469.EUBHAL_03265	0.0	1087.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,2482E@186801|Clostridia,25VE5@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS01075	CTP_synth_N,GATase
HLKFIFDC_02961	411469.EUBHAL_03098	1.12e-245	676.0	COG1266@1|root,COG1266@2|Bacteria,1VF60@1239|Firmicutes,24QSC@186801|Clostridia,25XU8@186806|Eubacteriaceae	186801|Clostridia	S	CAAX amino terminal protease family	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
HLKFIFDC_02962	411469.EUBHAL_03097	1.63e-199	553.0	COG2996@1|root,COG2996@2|Bacteria,1TQ1Z@1239|Firmicutes,2498C@186801|Clostridia,25VSX@186806|Eubacteriaceae	186801|Clostridia	S	S1 domain	cvfB	-	-	ko:K00243	-	-	-	-	ko00000	-	-	-	S1,S1_2
HLKFIFDC_02963	411469.EUBHAL_03096	7.74e-172	479.0	COG3884@1|root,COG3884@2|Bacteria,1TRH5@1239|Firmicutes,24G5K@186801|Clostridia,25WPJ@186806|Eubacteriaceae	186801|Clostridia	I	Acyl-ACP thioesterase	-	-	3.1.2.21	ko:K01071	ko00061,ko01100,map00061,map01100	-	R04014,R08157,R08158	RC00014,RC00039	ko00000,ko00001,ko01000,ko01004	-	-	-	Acyl-ACP_TE
HLKFIFDC_02964	411469.EUBHAL_03095	2.35e-67	204.0	2DQFX@1|root,336KU@2|Bacteria,1VP58@1239|Firmicutes,25HKT@186801|Clostridia	186801|Clostridia	S	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
HLKFIFDC_02974	411469.EUBHAL_00382	4.22e-52	164.0	COG1925@1|root,COG1925@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	-	-	-	-	-	-	-	-	-	-	-	-	PTS-HPr
HLKFIFDC_02975	411469.EUBHAL_00383	0.0	1209.0	COG1404@1|root,COG1404@2|Bacteria,1TQE0@1239|Firmicutes,25B1A@186801|Clostridia,25UW7@186806|Eubacteriaceae	186801|Clostridia	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
HLKFIFDC_02976	411469.EUBHAL_00385	5.07e-292	798.0	COG0500@1|root,COG0789@1|root,COG0789@2|Bacteria,COG2226@2|Bacteria,1TSDZ@1239|Firmicutes,248EY@186801|Clostridia,25ZHQ@186806|Eubacteriaceae	186801|Clostridia	KQ	MerR, DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1,Methyltransf_11,Methyltransf_25,Methyltransf_31
HLKFIFDC_02978	411469.EUBHAL_00387	4.18e-164	460.0	COG0730@1|root,COG0730@2|Bacteria,1TQBK@1239|Firmicutes,24A0G@186801|Clostridia	186801|Clostridia	S	membrane transporter protein	yfcA	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
HLKFIFDC_02979	411469.EUBHAL_00388	6.4e-235	646.0	28M41@1|root,2ZAI3@2|Bacteria,1UZMW@1239|Firmicutes,24ANU@186801|Clostridia,25XMN@186806|Eubacteriaceae	186801|Clostridia	S	Uncharacterized protein conserved in bacteria C-term(DUF2220)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2220
HLKFIFDC_02980	411469.EUBHAL_00389	0.0	1012.0	28I9Q@1|root,2Z8CD@2|Bacteria,1TQ4H@1239|Firmicutes,24B8Q@186801|Clostridia,25XIF@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02981	411469.EUBHAL_00390	7.12e-170	474.0	28MFF@1|root,2ZASX@2|Bacteria,1TQD0@1239|Firmicutes,24996@186801|Clostridia,25YDD@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02982	411469.EUBHAL_00391	0.0	2628.0	COG1196@1|root,COG1196@2|Bacteria,1TR05@1239|Firmicutes,24BXV@186801|Clostridia,25WTM@186806|Eubacteriaceae	186801|Clostridia	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02984	411469.EUBHAL_00392	1.13e-59	184.0	COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,24RIE@186801|Clostridia,25X2Y@186806|Eubacteriaceae	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
HLKFIFDC_02985	411469.EUBHAL_00393	0.0	951.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,24911@186801|Clostridia,25V2X@186806|Eubacteriaceae	186801|Clostridia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
HLKFIFDC_02986	411469.EUBHAL_00394	0.0	941.0	COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,247MS@186801|Clostridia,25VHC@186806|Eubacteriaceae	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
HLKFIFDC_02987	411469.EUBHAL_00395	3.91e-124	355.0	COG2816@1|root,COG2816@2|Bacteria,1VAYJ@1239|Firmicutes,24JR2@186801|Clostridia,25ZFN@186806|Eubacteriaceae	186801|Clostridia	L	NUDIX domain	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
HLKFIFDC_02988	411469.EUBHAL_01466	2.71e-286	783.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,25VW1@186806|Eubacteriaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	dacB2	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
HLKFIFDC_02989	411469.EUBHAL_01465	7.5e-167	465.0	COG0692@1|root,COG0692@2|Bacteria,1TPSN@1239|Firmicutes,247N9@186801|Clostridia,25VRH@186806|Eubacteriaceae	186801|Clostridia	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	-	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
HLKFIFDC_02990	411469.EUBHAL_01464	1.56e-82	243.0	COG1393@1|root,COG1393@2|Bacteria,1VA5Q@1239|Firmicutes,24JGY@186801|Clostridia,25WYC@186806|Eubacteriaceae	186801|Clostridia	P	Transcriptional regulator, Spx MgsR family	spxA	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC,Glutaredoxin
HLKFIFDC_02991	411469.EUBHAL_01462	6.32e-274	750.0	COG1865@1|root,COG1865@2|Bacteria,1TQHV@1239|Firmicutes,24AA4@186801|Clostridia,25UXS@186806|Eubacteriaceae	186801|Clostridia	S	Adenosylcobinamide amidohydrolase	cbiZ	-	-	-	-	-	-	-	-	-	-	-	CbiZ
HLKFIFDC_02992	411469.EUBHAL_01461	3.01e-273	749.0	COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,2491V@186801|Clostridia,25VQM@186806|Eubacteriaceae	186801|Clostridia	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
HLKFIFDC_02993	553973.CLOHYLEM_05677	1.88e-20	91.7	COG3395@1|root,COG3395@2|Bacteria,1TPNP@1239|Firmicutes,24AJF@186801|Clostridia,21Y1I@1506553|Lachnoclostridium	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	2.7.1.219,2.7.1.220	ko:K22129	-	-	-	-	ko00000,ko01000	-	-	-	DUF1357_C,DUF1537
HLKFIFDC_02994	411469.EUBHAL_01203	3.89e-241	662.0	COG1198@1|root,COG1198@2|Bacteria,1UI22@1239|Firmicutes,25EJI@186801|Clostridia,25ZK0@186806|Eubacteriaceae	186801|Clostridia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02995	411469.EUBHAL_01202	1.33e-186	519.0	COG1512@1|root,COG1512@2|Bacteria,1VB4Q@1239|Firmicutes,24PER@186801|Clostridia	186801|Clostridia	S	TPM domain	-	-	-	-	-	-	-	-	-	-	-	-	TPM_phosphatase
HLKFIFDC_02996	411469.EUBHAL_01200	6.74e-165	466.0	COG2888@1|root,COG2888@2|Bacteria,1UK70@1239|Firmicutes,25FNQ@186801|Clostridia,25ZUG@186806|Eubacteriaceae	186801|Clostridia	J	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_02997	411469.EUBHAL_01199	1.65e-176	493.0	COG1512@1|root,COG1512@2|Bacteria,1V8N5@1239|Firmicutes,24H2W@186801|Clostridia,25XZ7@186806|Eubacteriaceae	186801|Clostridia	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
HLKFIFDC_02999	411469.EUBHAL_00310	1.9e-48	161.0	2E7V3@1|root,3329Y@2|Bacteria,1VHFN@1239|Firmicutes,24SN8@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_03000	411469.EUBHAL_00309	3.76e-123	350.0	COG3012@1|root,COG3012@2|Bacteria,1V1CC@1239|Firmicutes,24FYC@186801|Clostridia,25WAC@186806|Eubacteriaceae	186801|Clostridia	S	SEC-C motif	secA_2	-	-	-	-	-	-	-	-	-	-	-	SEC-C
HLKFIFDC_03001	411469.EUBHAL_00308	4.51e-261	715.0	2EF3E@1|root,338WH@2|Bacteria,1VJTP@1239|Firmicutes,24U3K@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_03002	411469.EUBHAL_00307	0.0	1089.0	COG1227@1|root,COG1227@2|Bacteria,1TPH6@1239|Firmicutes,248RQ@186801|Clostridia,25US0@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	ppaC	-	3.6.1.1	ko:K15986	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	CBS,DHH,DHHA2,DRTGG
HLKFIFDC_03003	411469.EUBHAL_00305	0.0	1516.0	COG1199@1|root,COG1199@2|Bacteria,1TPNB@1239|Firmicutes,248ZI@186801|Clostridia,25VNQ@186806|Eubacteriaceae	186801|Clostridia	L	HELICc2	dinG	-	3.1.12.1,3.6.4.12	ko:K07464,ko:K10844	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko02048,ko03021,ko03400	-	-	-	DEAD,DEAD_2,HBB,Helicase_C_2,PDDEXK_1
HLKFIFDC_03004	411469.EUBHAL_00304	5.4e-198	550.0	COG4399@1|root,COG4399@2|Bacteria,1TQDH@1239|Firmicutes,24K94@186801|Clostridia,25WHZ@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
HLKFIFDC_03005	411469.EUBHAL_00303	2.93e-176	490.0	COG0846@1|root,COG0846@2|Bacteria,1TQKD@1239|Firmicutes,2491J@186801|Clostridia,25V15@186806|Eubacteriaceae	186801|Clostridia	K	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
HLKFIFDC_03006	411469.EUBHAL_00302	0.0	1270.0	COG2214@1|root,COG2214@2|Bacteria,1UJW2@1239|Firmicutes,25FBS@186801|Clostridia	186801|Clostridia	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_7,TPR_8
HLKFIFDC_03007	411469.EUBHAL_00301	0.0	1082.0	COG0443@1|root,COG0443@2|Bacteria,1TQ6N@1239|Firmicutes,248UV@186801|Clostridia,25VIB@186806|Eubacteriaceae	186801|Clostridia	O	MreB/Mbl protein	-	-	-	ko:K04045	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
HLKFIFDC_03008	411469.EUBHAL_00300	4.61e-70	219.0	COG1595@1|root,COG1595@2|Bacteria,1VACS@1239|Firmicutes,24KS7@186801|Clostridia,25XZV@186806|Eubacteriaceae	186801|Clostridia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HLKFIFDC_03009	411469.EUBHAL_00300	5.99e-92	283.0	COG1595@1|root,COG1595@2|Bacteria,1VACS@1239|Firmicutes,24KS7@186801|Clostridia,25XZV@186806|Eubacteriaceae	186801|Clostridia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HLKFIFDC_03010	411469.EUBHAL_00299	2.45e-53	167.0	COG2608@1|root,COG2608@2|Bacteria,1VETC@1239|Firmicutes,24QJU@186801|Clostridia,25XFR@186806|Eubacteriaceae	186801|Clostridia	P	mercury ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	HMA
HLKFIFDC_03011	411469.EUBHAL_02860	9.27e-307	840.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,25V1G@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
HLKFIFDC_03012	411469.EUBHAL_02859	2.2e-292	800.0	COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,247Q3@186801|Clostridia,25V0E@186806|Eubacteriaceae	186801|Clostridia	P	Potassium uptake protein	ktrB	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
HLKFIFDC_03013	411469.EUBHAL_02858	1.55e-148	419.0	COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,249C2@186801|Clostridia,25WED@186806|Eubacteriaceae	186801|Clostridia	P	TrkA-N domain	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
HLKFIFDC_03014	411469.EUBHAL_02538	4.32e-100	290.0	COG0735@1|root,COG0735@2|Bacteria,1V970@1239|Firmicutes,24QK7@186801|Clostridia,25ZTA@186806|Eubacteriaceae	186801|Clostridia	L	Ferric uptake regulator family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
HLKFIFDC_03015	411469.EUBHAL_02648	1e-246	677.0	COG0673@1|root,COG0673@2|Bacteria,1TQSS@1239|Firmicutes,249QZ@186801|Clostridia,25ZE9@186806|Eubacteriaceae	186801|Clostridia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	ko:K22230	ko00562,ko01120,map00562,map01120	-	R09954	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA
HLKFIFDC_03016	411469.EUBHAL_02647	4.68e-192	533.0	COG0561@1|root,COG0561@2|Bacteria,1TSGF@1239|Firmicutes,24CTF@186801|Clostridia	186801|Clostridia	S	Sucrose-6F-phosphate phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
HLKFIFDC_03017	411469.EUBHAL_02646	6.12e-183	509.0	COG1349@1|root,COG1349@2|Bacteria,1UZ6T@1239|Firmicutes,24B16@186801|Clostridia,25XAU@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K02081,ko:K02530	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
HLKFIFDC_03018	411469.EUBHAL_02645	6.09e-130	369.0	COG0655@1|root,COG0655@2|Bacteria,1UZH5@1239|Firmicutes,24D03@186801|Clostridia,25ZPE@186806|Eubacteriaceae	186801|Clostridia	S	Flavodoxin-like fold	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
HLKFIFDC_03019	411469.EUBHAL_02644	2.63e-142	401.0	COG0560@1|root,COG0560@2|Bacteria,1TQJY@1239|Firmicutes,2493S@186801|Clostridia,25V04@186806|Eubacteriaceae	186801|Clostridia	E	phosphoserine phosphatase homoserine phosphotransferase bifunctional protein	thrH	-	2.7.1.39,3.1.3.3	ko:K02203	ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00680,map01100,map01110,map01120,map01130,map01230	M00018	R00582,R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD,Hydrolase
HLKFIFDC_03020	411469.EUBHAL_00234	1.2e-205	569.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,248N9@186801|Clostridia,25VXH@186806|Eubacteriaceae	186801|Clostridia	S	Uncharacterised protein, DegV family COG1307	-	-	-	-	-	-	-	-	-	-	-	-	DegV
HLKFIFDC_03021	411469.EUBHAL_00232	1.45e-185	515.0	COG0647@1|root,COG0647@2|Bacteria,1TQGM@1239|Firmicutes,24B6W@186801|Clostridia,25VPM@186806|Eubacteriaceae	186801|Clostridia	G	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K02566	-	-	-	-	ko00000	-	-	-	Hydrolase_6,Hydrolase_like
HLKFIFDC_03022	903814.ELI_0046	7.97e-171	486.0	COG1063@1|root,COG1063@2|Bacteria,1TPWP@1239|Firmicutes,24ATV@186801|Clostridia,25VIJ@186806|Eubacteriaceae	186801|Clostridia	E	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
HLKFIFDC_03023	903814.ELI_0054	1.57e-198	556.0	COG1063@1|root,COG1063@2|Bacteria,1U9ZD@1239|Firmicutes,24EJR@186801|Clostridia,25YI6@186806|Eubacteriaceae	186801|Clostridia	C	COG COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
HLKFIFDC_03024	903814.ELI_0053	1.74e-159	461.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	5.1.3.38	ko:K21909	-	-	-	-	ko00000,ko01000	-	-	-	AP_endonuc_2
HLKFIFDC_03025	903814.ELI_0051	1.08e-257	717.0	COG0579@1|root,COG1251@1|root,COG0579@2|Bacteria,COG1251@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia,25V7H@186806|Eubacteriaceae	186801|Clostridia	P	FAD dependent oxidoreductase	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD
HLKFIFDC_03026	903814.ELI_0050	5.79e-207	583.0	COG0446@1|root,COG0446@2|Bacteria,1TQH5@1239|Firmicutes,247YR@186801|Clostridia,25VR2@186806|Eubacteriaceae	186801|Clostridia	C	Pyridine nucleotide-disulfide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_3
HLKFIFDC_03027	903814.ELI_0049	5.49e-52	167.0	COG3862@1|root,COG3862@2|Bacteria,1VA4U@1239|Firmicutes,24MN9@186801|Clostridia,25WVW@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF1667)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1667
HLKFIFDC_03028	903814.ELI_0048	2.38e-299	825.0	COG1070@1|root,COG1070@2|Bacteria,1U0HE@1239|Firmicutes,24EBF@186801|Clostridia,25UW2@186806|Eubacteriaceae	186801|Clostridia	H	FGGY family of carbohydrate kinases, C-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
HLKFIFDC_03029	411469.EUBHAL_00230	4.33e-153	430.0	COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,249XB@186801|Clostridia,25W3V@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
HLKFIFDC_03030	903814.ELI_1422	9.71e-84	262.0	COG2390@1|root,COG2390@2|Bacteria,1TPUB@1239|Firmicutes,24EXD@186801|Clostridia,25VMS@186806|Eubacteriaceae	186801|Clostridia	K	Putative sugar-binding domain	-	-	-	ko:K05346	-	-	-	-	ko00000,ko03000	-	-	-	Sugar-bind
HLKFIFDC_03031	411469.EUBHAL_00292	3.28e-157	441.0	COG0176@1|root,COG0176@2|Bacteria,1W77Z@1239|Firmicutes,25MNF@186801|Clostridia,25YMU@186806|Eubacteriaceae	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TAL_FSA
HLKFIFDC_03032	411469.EUBHAL_00291	0.0	1587.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25USQ@186806|Eubacteriaceae	186801|Clostridia	C	Pyruvate formate lyase-like	-	-	2.3.1.54,4.3.99.4	ko:K00656,ko:K20038	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
HLKFIFDC_03033	411469.EUBHAL_00290	4.4e-215	594.0	COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,24871@186801|Clostridia,25W5G@186806|Eubacteriaceae	186801|Clostridia	C	glycyl-radical enzyme activating protein family	hpdA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4,Fer4_12,Radical_SAM
HLKFIFDC_03034	411469.EUBHAL_00289	1.05e-169	474.0	COG1349@1|root,COG1349@2|Bacteria,1TNYH@1239|Firmicutes,24BT5@186801|Clostridia,25ZNQ@186806|Eubacteriaceae	186801|Clostridia	K	DeoR C terminal sensor domain	-	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
HLKFIFDC_03035	411469.EUBHAL_00206	1.41e-21	87.8	COG1672@1|root,COG1672@2|Bacteria,1W4XZ@1239|Firmicutes,2551K@186801|Clostridia,25Z7T@186806|Eubacteriaceae	186801|Clostridia	S	Predicted AAA-ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like
HLKFIFDC_03036	411469.EUBHAL_00287	0.0	1669.0	COG0642@1|root,COG2199@1|root,COG2199@2|Bacteria,COG2205@2|Bacteria,1V1A1@1239|Firmicutes,24CYN@186801|Clostridia,25W77@186806|Eubacteriaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
HLKFIFDC_03037	411469.EUBHAL_00343	3.8e-25	94.4	COG2364@1|root,COG2364@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_03038	411469.EUBHAL_00344	5.29e-29	103.0	COG2364@1|root,COG2364@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HLKFIFDC_03039	411469.EUBHAL_00345	2.33e-191	530.0	COG0406@1|root,COG0406@2|Bacteria,1U7UE@1239|Firmicutes,24F5B@186801|Clostridia,25W9Q@186806|Eubacteriaceae	186801|Clostridia	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
HLKFIFDC_03041	411469.EUBHAL_02009	0.0	1206.0	COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,248F8@186801|Clostridia,25VQ0@186806|Eubacteriaceae	186801|Clostridia	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
HLKFIFDC_03042	411469.EUBHAL_00762	2.77e-270	740.0	COG0246@1|root,COG0246@2|Bacteria,1TPZU@1239|Firmicutes,248J5@186801|Clostridia	186801|Clostridia	G	Mannitol dehydrogenase	mtlD	-	1.1.1.17	ko:K00009	ko00051,map00051	-	R02703	RC00085	ko00000,ko00001,ko01000	-	-	-	Mannitol_dh,Mannitol_dh_C
HLKFIFDC_03043	411469.EUBHAL_00761	0.0	1136.0	COG2213@1|root,COG4668@1|root,COG2213@2|Bacteria,COG4668@2|Bacteria,1TPE3@1239|Firmicutes,24A04@186801|Clostridia,25UWX@186806|Eubacteriaceae	186801|Clostridia	G	PTS system, Lactose/Cellobiose specific IIB subunit	mtlA	-	2.7.1.197	ko:K02798,ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	M00274	R02704	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
HLKFIFDC_03044	411469.EUBHAL_00759	0.0	1359.0	COG3711@1|root,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,248PT@186801|Clostridia,25WY5@186806|Eubacteriaceae	186801|Clostridia	GKT	Psort location Cytoplasmic, score	-	-	-	ko:K03483	-	-	-	-	ko00000,ko03000	-	-	-	HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB
HLKFIFDC_03045	1280698.AUJS01000048_gene411	1.09e-62	193.0	COG0454@1|root,COG0456@2|Bacteria,1VAFS@1239|Firmicutes,24MUI@186801|Clostridia	186801|Clostridia	K	Acetyltransferase GNAT family	-	-	-	ko:K03826	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_10,Acetyltransf_7
HLKFIFDC_03046	411469.EUBHAL_02595	3.15e-206	572.0	COG0583@1|root,COG0583@2|Bacteria,1TP77@1239|Firmicutes,248CX@186801|Clostridia,25VMF@186806|Eubacteriaceae	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
HLKFIFDC_03047	411459.RUMOBE_00715	1.39e-106	307.0	COG0716@1|root,COG0716@2|Bacteria,1V45R@1239|Firmicutes,24HDR@186801|Clostridia,3Y09P@572511|Blautia	186801|Clostridia	C	Flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_4
HLKFIFDC_03048	411469.EUBHAL_02593	3.07e-195	540.0	COG0599@1|root,COG1917@1|root,COG0599@2|Bacteria,COG1917@2|Bacteria,1TRVH@1239|Firmicutes,249JY@186801|Clostridia,25VK4@186806|Eubacteriaceae	186801|Clostridia	S	conserved protein, contains double-stranded beta-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	CMD,Cupin_2
HLKFIFDC_03049	411469.EUBHAL_02592	9.94e-243	666.0	COG0667@1|root,COG0667@2|Bacteria,1TQJC@1239|Firmicutes,25B10@186801|Clostridia,25VPB@186806|Eubacteriaceae	186801|Clostridia	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
HLKFIFDC_03050	518637.EUBIFOR_00728	3.11e-35	119.0	COG3311@1|root,COG3311@2|Bacteria,1V8AE@1239|Firmicutes,3VU5J@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
HLKFIFDC_03051	411459.RUMOBE_02158	2.3e-26	104.0	29YMG@1|root,30KGY@2|Bacteria,1V4T3@1239|Firmicutes,24I7T@186801|Clostridia,3Y0BR@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
HLKFIFDC_03052	411469.EUBHAL_02755	4.96e-57	178.0	COG1925@1|root,COG1925@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	ptsH	-	-	ko:K11184,ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
HLKFIFDC_03053	411469.EUBHAL_02756	1.49e-53	167.0	COG1193@1|root,COG1193@2|Bacteria	2|Bacteria	L	negative regulation of DNA recombination	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
HLKFIFDC_03054	411469.EUBHAL_02757	7.5e-83	245.0	COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,24J8Y@186801|Clostridia,25WVB@186806|Eubacteriaceae	186801|Clostridia	J	Psort location Cytoplasmic, score	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
HLKFIFDC_03055	411469.EUBHAL_02758	2.41e-173	483.0	COG2220@1|root,COG2220@2|Bacteria,1V3HY@1239|Firmicutes,24HK9@186801|Clostridia,25WSF@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	folD4	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
HLKFIFDC_03056	411469.EUBHAL_02759	2.18e-220	607.0	COG0648@1|root,COG0648@2|Bacteria,1TP1D@1239|Firmicutes,2499E@186801|Clostridia,25VRZ@186806|Eubacteriaceae	186801|Clostridia	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
HLKFIFDC_03057	1280698.AUJS01000019_gene1692	0.0	1149.0	COG0642@1|root,COG0745@1|root,COG0642@2|Bacteria,COG0745@2|Bacteria,1UYZX@1239|Firmicutes,25E9T@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2,CheB_methylest,CheR,CheR_N,GGDEF,HATPase_c,HisKA,PAS_10,PAS_3,PAS_9,Response_reg,SnoaL_3
HLKFIFDC_03058	1034347.CAHJ01000051_gene23	1.35e-42	161.0	COG3385@1|root,COG3385@2|Bacteria,1UZFU@1239|Firmicutes,4IQYK@91061|Bacilli	91061|Bacilli	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
HLKFIFDC_03059	411469.EUBHAL_01568	2.22e-37	130.0	COG0389@1|root,COG0389@2|Bacteria,1VVTB@1239|Firmicutes,250NY@186801|Clostridia,25ZNI@186806|Eubacteriaceae	2|Bacteria	L	DNA-damage repair protein (DNA polymerase IV) K00961	dinB	-	2.7.7.7	ko:K02346,ko:K03502,ko:K14161	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
## 2727 queries scanned
## Total time (seconds): 306.84917306900024
## Rate: 8.89 q/s