GCA_902387655.1 - 4 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

gnlProkkaEEPAIMML_26 (original name was: gnl|Prokka|EEPAIMML_26)

Region	Type	From	To	Most similar known cluster		Similarity
Region 14.1	ranthipeptide	82,298	103,905

gnlProkkaEEPAIMML_54 (original name was: gnl|Prokka|EEPAIMML_54)

Region	Type	From	To	Most similar known cluster		Similarity
Region 41.1	cyclic-lactone-autoinducer	1	11,844

gnlProkkaEEPAIMML_63 (original name was: gnl|Prokka|EEPAIMML_63)

Region	Type	From	To	Most similar known cluster		Similarity
Region 49.1	RRE-containing	22,058	42,321

gnlProkkaEEPAIMML_69 (original name was: gnl|Prokka|EEPAIMML_69)

Region	Type	From	To	Most similar known cluster		Similarity
Region 55.1	NRPS,HR-T2PKS	13,584	76,221

Region	Type	From	To	Similarity
Region 14.1	ranthipeptide	82,298	103,905
Region 41.1	cyclic-lactone-autoinducer	1	11,844
Region 49.1	RRE-containing	22,058	42,321
Region 55.1	NRPS,HR-T2PKS	13,584	76,221

No secondary metabolite regions were found in these records:: gnlProkkaEEPAIMML_4 (original name was: gnl|Prokka|EEPAIMML_4); gnlProkkaEEPAIMML_6 (original name was: gnl|Prokka|EEPAIMML_6); gnlProkkaEEPAIMML_8 (original name was: gnl|Prokka|EEPAIMML_8); gnlProkkaEEPAIMML_10 (original name was: gnl|Prokka|EEPAIMML_10); gnlProkkaEEPAIMML_12 (original name was: gnl|Prokka|EEPAIMML_12); gnlProkkaEEPAIMML_13 (original name was: gnl|Prokka|EEPAIMML_13); gnlProkkaEEPAIMML_16 (original name was: gnl|Prokka|EEPAIMML_16); gnlProkkaEEPAIMML_18 (original name was: gnl|Prokka|EEPAIMML_18); gnlProkkaEEPAIMML_19 (original name was: gnl|Prokka|EEPAIMML_19); gnlProkkaEEPAIMML_20 (original name was: gnl|Prokka|EEPAIMML_20); gnlProkkaEEPAIMML_23 (original name was: gnl|Prokka|EEPAIMML_23); gnlProkkaEEPAIMML_24 (original name was: gnl|Prokka|EEPAIMML_24); gnlProkkaEEPAIMML_25 (original name was: gnl|Prokka|EEPAIMML_25); gnlProkkaEEPAIMML_27 (original name was: gnl|Prokka|EEPAIMML_27); gnlProkkaEEPAIMML_28 (original name was: gnl|Prokka|EEPAIMML_28); gnlProkkaEEPAIMML_29 (original name was: gnl|Prokka|EEPAIMML_29); gnlProkkaEEPAIMML_30 (original name was: gnl|Prokka|EEPAIMML_30); gnlProkkaEEPAIMML_31 (original name was: gnl|Prokka|EEPAIMML_31); gnlProkkaEEPAIMML_32 (original name was: gnl|Prokka|EEPAIMML_32); gnlProkkaEEPAIMML_33 (original name was: gnl|Prokka|EEPAIMML_33); gnlProkkaEEPAIMML_35 (original name was: gnl|Prokka|EEPAIMML_35); gnlProkkaEEPAIMML_36 (original name was: gnl|Prokka|EEPAIMML_36); gnlProkkaEEPAIMML_37 (original name was: gnl|Prokka|EEPAIMML_37); gnlProkkaEEPAIMML_38 (original name was: gnl|Prokka|EEPAIMML_38); gnlProkkaEEPAIMML_39 (original name was: gnl|Prokka|EEPAIMML_39); gnlProkkaEEPAIMML_40 (original name was: gnl|Prokka|EEPAIMML_40); gnlProkkaEEPAIMML_41 (original name was: gnl|Prokka|EEPAIMML_41); gnlProkkaEEPAIMML_42 (original name was: gnl|Prokka|EEPAIMML_42); gnlProkkaEEPAIMML_43 (original name was: gnl|Prokka|EEPAIMML_43); gnlProkkaEEPAIMML_44 (original name was: gnl|Prokka|EEPAIMML_44); gnlProkkaEEPAIMML_45 (original name was: gnl|Prokka|EEPAIMML_45); gnlProkkaEEPAIMML_46 (original name was: gnl|Prokka|EEPAIMML_46); gnlProkkaEEPAIMML_47 (original name was: gnl|Prokka|EEPAIMML_47); gnlProkkaEEPAIMML_48 (original name was: gnl|Prokka|EEPAIMML_48); gnlProkkaEEPAIMML_49 (original name was: gnl|Prokka|EEPAIMML_49); gnlProkkaEEPAIMML_50 (original name was: gnl|Prokka|EEPAIMML_50); gnlProkkaEEPAIMML_51 (original name was: gnl|Prokka|EEPAIMML_51); gnlProkkaEEPAIMML_52 (original name was: gnl|Prokka|EEPAIMML_52); gnlProkkaEEPAIMML_53 (original name was: gnl|Prokka|EEPAIMML_53); gnlProkkaEEPAIMML_55 (original name was: gnl|Prokka|EEPAIMML_55); gnlProkkaEEPAIMML_56 (original name was: gnl|Prokka|EEPAIMML_56); gnlProkkaEEPAIMML_57 (original name was: gnl|Prokka|EEPAIMML_57); gnlProkkaEEPAIMML_58 (original name was: gnl|Prokka|EEPAIMML_58); gnlProkkaEEPAIMML_60 (original name was: gnl|Prokka|EEPAIMML_60); gnlProkkaEEPAIMML_61 (original name was: gnl|Prokka|EEPAIMML_61); gnlProkkaEEPAIMML_62 (original name was: gnl|Prokka|EEPAIMML_62); gnlProkkaEEPAIMML_64 (original name was: gnl|Prokka|EEPAIMML_64); gnlProkkaEEPAIMML_65 (original name was: gnl|Prokka|EEPAIMML_65); gnlProkkaEEPAIMML_66 (original name was: gnl|Prokka|EEPAIMML_66); gnlProkkaEEPAIMML_67 (original name was: gnl|Prokka|EEPAIMML_67); gnlProkkaEEPAIMML_68 (original name was: gnl|Prokka|EEPAIMML_68); gnlProkkaEEPAIMML_70 (original name was: gnl|Prokka|EEPAIMML_70); gnlProkkaEEPAIMML_71 (original name was: gnl|Prokka|EEPAIMML_71); gnlProkkaEEPAIMML_72 (original name was: gnl|Prokka|EEPAIMML_72); gnlProkkaEEPAIMML_73 (original name was: gnl|Prokka|EEPAIMML_73); gnlProkkaEEPAIMML_74 (original name was: gnl|Prokka|EEPAIMML_74)

Compact view

gnlProkkaEEPAIMML_26 - Region 1 - ranthipeptide

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Location: 82,298 - 103,905 nt. (total: 21,608 nt) Show pHMM detection rules used

ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or (YcaO or TIGR03604))))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene overview

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaEEPAIMML_54 - Region 1 - cyclic-lactone-autoinducer

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Location: 1 - 11,844 nt. (total: 11,844 nt) Show pHMM detection rules used

Region on contig edge.

cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaEEPAIMML_63 - Region 1 - RRE-containing

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Location: 22,058 - 42,321 nt. (total: 20,264 nt) Show pHMM detection rules used

RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaEEPAIMML_69 - Region 1 - HR-T2PKS,NRPS

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Location: 13,584 - 76,221 nt. (total: 62,638 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))
HR-T2PKS: (hr-t2pks-ksa and (t2fas or APE_KS2 or ketoacyl-synt))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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NRPS/PKS domains

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters from MIBiG 3.1

No matches found.

Module view

Legend

NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 13583 - 76221:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Ile - X)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 2, location 13583 - 60915:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Ile - X)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 3, location 34022 - 76221:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Ile - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg55_31

Search NORINE for peptide: strict or relaxed

AMP-binding (457..845): Ile

nrpys: Ile

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DASFLGGVYK
Nearest Stachelhaus code(s):: Ile DALFMGGVYK (56% 8Å match)
Stachelhaus code match:: 80% (moderate)

AMP-binding (1479..1869): X

nrpys: Asp, Asn, Glu, Gln, Aad

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DMKNLGTVSK
Nearest Stachelhaus code(s):: Asp DMKDLGMVDK (53% 8Å match)
Stachelhaus code match:: 70% (weak)