## Fri May  2 07:17:19 2025
## emapper-2.1.12
## /home/m128030022/anaconda3/envs/eggnog/bin/emapper.py -i /home/m128030022/prbbiotics_cp/prokka_results/GCA_902505525.1/GCA_902505525.1.faa --temp_dir /home/m128030022/prbbiotics_cp/probiotics_new/databases/probiotics_DB/probiotics_db/GCA_902505525.1/2.eggNOGmapper --output_dir /home/m128030022/prbbiotics_cp/probiotics_new/databases/probiotics_DB/probiotics_db/GCA_902505525.1/2.eggNOGmapper --output eggNOG_out --override --cpu 14 -m diamond --sensmode fast
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
IOLKFBCL_00002	1147128.BAST_0864	2.35e-40	144.0	29W79@1|root,30HSG@2|Bacteria,2IC42@201174|Actinobacteria,4CZCZ@85004|Bifidobacteriales	201174|Actinobacteria	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_36
IOLKFBCL_00003	1147128.BAST_0865	5.14e-112	324.0	2A2Z4@1|root,30RDK@2|Bacteria,2IDG0@201174|Actinobacteria,4D038@85004|Bifidobacteriales	201174|Actinobacteria	S	Transcription factor WhiB	-	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
IOLKFBCL_00004	326426.Bbr_1513	3.57e-130	370.0	COG1192@1|root,COG1192@2|Bacteria,2ICWE@201174|Actinobacteria,4D14U@85004|Bifidobacteriales	201174|Actinobacteria	D	AAA domain	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
IOLKFBCL_00005	326426.Bbr_1514	7.39e-54	168.0	2AYK3@1|root,31QQD@2|Bacteria,2ISGT@201174|Actinobacteria,4D1C9@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00006	216816.GS08_08570	0.0	991.0	COG0488@1|root,COG0488@2|Bacteria,2GKZC@201174|Actinobacteria,4CZ9C@85004|Bifidobacteriales	201174|Actinobacteria	S	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
IOLKFBCL_00007	326426.Bbr_1516	2.17e-122	349.0	COG0454@1|root,COG0456@2|Bacteria,2IQQX@201174|Actinobacteria,4D1CY@85004|Bifidobacteriales	201174|Actinobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
IOLKFBCL_00008	326426.Bbr_1517	2.32e-152	428.0	COG0560@1|root,COG0560@2|Bacteria,2HZV3@201174|Actinobacteria,4D1VN@85004|Bifidobacteriales	201174|Actinobacteria	E	haloacid dehalogenase-like hydrolase	-	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	HAD
IOLKFBCL_00009	326426.Bbr_1518	0.0	2835.0	COG3087@1|root,COG3087@2|Bacteria,2HRQY@201174|Actinobacteria,4CYQ9@85004|Bifidobacteriales	201174|Actinobacteria	D	Cell surface antigen C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Antigen_C
IOLKFBCL_00011	326426.Bbr_1527	7.45e-51	161.0	2EJJI@1|root,33DAG@2|Bacteria,2GW42@201174|Actinobacteria,4D1C7@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00012	326426.Bbr_1528	1.67e-187	522.0	2B0U3@1|root,31T6M@2|Bacteria,2IDXF@201174|Actinobacteria,4D01Y@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TrbL
IOLKFBCL_00013	33905.BTHE_1990	1.99e-303	839.0	COG4584@1|root,COG4584@2|Bacteria,2IBDV@201174|Actinobacteria,4CZS6@85004|Bifidobacteriales	201174|Actinobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_7,IstB_IS21,rve
IOLKFBCL_00014	216816.GS08_06500	1.98e-181	504.0	COG1484@1|root,COG1484@2|Bacteria,2I90G@201174|Actinobacteria,4D05J@85004|Bifidobacteriales	201174|Actinobacteria	L	IstB-like ATP binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
IOLKFBCL_00015	1437609.BCAL_0558	9.69e-45	148.0	29YW1@1|root,30KSH@2|Bacteria,2HZKD@201174|Actinobacteria,4D0T1@85004|Bifidobacteriales	201174|Actinobacteria	S	PrgI family protein	-	-	-	-	-	-	-	-	-	-	-	-	PrgI
IOLKFBCL_00016	1437609.BCAL_0559	0.0	1151.0	COG3451@1|root,COG3451@2|Bacteria,2H6W2@201174|Actinobacteria,4CYWV@85004|Bifidobacteriales	201174|Actinobacteria	U	type IV secretory pathway VirB4	-	-	-	-	-	-	-	-	-	-	-	-	DUF87
IOLKFBCL_00017	326426.Bbr_1530	1.87e-254	706.0	COG0741@1|root,COG3942@1|root,COG0741@2|Bacteria,COG3942@2|Bacteria,2I9VT@201174|Actinobacteria,4D074@85004|Bifidobacteriales	201174|Actinobacteria	M	CHAP domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,SLT
IOLKFBCL_00018	326426.Bbr_1531	1.74e-246	684.0	2AQRU@1|root,31FZM@2|Bacteria,2IABZ@201174|Actinobacteria,4D0HM@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00019	502558.EGYY_18450	3.66e-58	190.0	2B2E5@1|root,31UYQ@2|Bacteria,2HWCJ@201174|Actinobacteria,4CY8Z@84998|Coriobacteriia	84998|Coriobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00020	502558.EGYY_18460	8.15e-183	523.0	COG4637@1|root,COG4637@2|Bacteria	2|Bacteria	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21
IOLKFBCL_00021	326426.Bbr_0024	6.17e-261	715.0	COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria,4D0DN@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase and inactivated derivatives IS30 family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
IOLKFBCL_00023	1235802.C823_03073	4.11e-34	123.0	COG1595@1|root,COG1595@2|Bacteria,1V1AX@1239|Firmicutes,24EM3@186801|Clostridia,25XG2@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r4_2
IOLKFBCL_00024	457412.RSAG_02028	0.0	970.0	COG0577@1|root,COG0577@2|Bacteria,1TRAS@1239|Firmicutes,248SQ@186801|Clostridia,3WGIS@541000|Ruminococcaceae	186801|Clostridia	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
IOLKFBCL_00025	411471.SUBVAR_04489	6.69e-142	402.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,3WH0X@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IOLKFBCL_00026	445335.CBN_0751	4.66e-147	422.0	COG0642@1|root,COG2205@2|Bacteria,1TT7F@1239|Firmicutes,247UJ@186801|Clostridia,36G6U@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
IOLKFBCL_00027	742733.HMPREF9469_03308	1.34e-137	392.0	COG0745@1|root,COG0745@2|Bacteria,1TT12@1239|Firmicutes,24AB1@186801|Clostridia,21XX7@1506553|Lachnoclostridium	186801|Clostridia	K	COG COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
IOLKFBCL_00028	411483.FAEPRAA2165_02038	1.69e-30	108.0	COG2909@1|root,COG2909@2|Bacteria,1VGAF@1239|Firmicutes,24SMP@186801|Clostridia,3WK3Y@541000|Ruminococcaceae	186801|Clostridia	K	trisaccharide binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
IOLKFBCL_00029	216816.GS08_10035	6.49e-57	193.0	COG0477@1|root,COG0477@2|Bacteria,2I3AP@201174|Actinobacteria,4D0YC@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
IOLKFBCL_00030	1394175.AWUN01000008_gene1504	2.62e-152	432.0	COG0845@1|root,COG0845@2|Bacteria,2IFY7@201174|Actinobacteria,4D13B@85004|Bifidobacteriales	201174|Actinobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
IOLKFBCL_00031	1147128.BAST_0870	1.01e-164	461.0	COG1136@1|root,COG1136@2|Bacteria,2GK3I@201174|Actinobacteria,4D0TX@85004|Bifidobacteriales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IOLKFBCL_00032	1147128.BAST_0871	2.94e-224	624.0	COG0577@1|root,COG0577@2|Bacteria,2HXTZ@201174|Actinobacteria,4CZYZ@85004|Bifidobacteriales	201174|Actinobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
IOLKFBCL_00033	1147128.BAST_0872	7.02e-114	327.0	28KKS@1|root,2ZA5I@2|Bacteria,2IM3G@201174|Actinobacteria,4D13X@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00034	762211.BSTEL_0440	3.57e-267	735.0	COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria,4D0ME@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K07485	-	-	-	-	ko00000	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
IOLKFBCL_00036	762211.BSTEL_0160	1.87e-164	464.0	COG5006@1|root,COG5006@2|Bacteria,2GJKB@201174|Actinobacteria,4D03A@85004|Bifidobacteriales	201174|Actinobacteria	S	EamA-like transporter family	-	-	-	ko:K11939	-	-	-	-	ko00000,ko02000	2.A.7.3.6	-	-	EamA
IOLKFBCL_00037	1437610.BREU_1625	1.37e-228	637.0	COG3464@1|root,COG3464@2|Bacteria,2IP45@201174|Actinobacteria,4D04T@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
IOLKFBCL_00038	1134413.ANNK01000144_gene3847	1.19e-14	75.9	2B0KJ@1|root,31SY8@2|Bacteria,1UAIC@1239|Firmicutes,4IKWU@91061|Bacilli,1ZPB1@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00040	1437608.BBIA_0785	7.79e-16	75.9	COG0582@1|root,COG0582@2|Bacteria,2GISN@201174|Actinobacteria,4CZA9@85004|Bifidobacteriales	201174|Actinobacteria	L	Phage integrase family	intA	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
IOLKFBCL_00042	326426.Bbr_1074	1.51e-26	102.0	2B7KG@1|root,320RD@2|Bacteria,2H4J4@201174|Actinobacteria,4D260@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00043	1437609.BCAL_0606	3.87e-95	290.0	COG0582@1|root,COG0582@2|Bacteria,2GISN@201174|Actinobacteria,4CZA9@85004|Bifidobacteriales	201174|Actinobacteria	L	Phage integrase family	intA	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
IOLKFBCL_00044	702459.BBPR_0778	1.95e-195	548.0	COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria,4D0DN@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase and inactivated derivatives IS30 family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
IOLKFBCL_00047	1226325.HMPREF1548_01586	2.32e-212	593.0	2CET6@1|root,2Z92J@2|Bacteria,1TQGV@1239|Firmicutes,24ARS@186801|Clostridia,36RZZ@31979|Clostridiaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 7.50	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00048	1437609.BCAL_0334	8.96e-149	430.0	COG1672@1|root,COG1672@2|Bacteria,2GWBV@201174|Actinobacteria,4CZV8@85004|Bifidobacteriales	201174|Actinobacteria	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
IOLKFBCL_00049	326426.Bbr_0428	0.0	900.0	COG0477@1|root,COG2814@2|Bacteria,2GIZX@201174|Actinobacteria,4CZWX@85004|Bifidobacteriales	201174|Actinobacteria	U	Drug resistance MFS transporter, drug H antiporter-2 family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
IOLKFBCL_00050	216816.GS08_02200	1.29e-266	737.0	COG1914@1|root,COG1914@2|Bacteria,2GJSM@201174|Actinobacteria,4CZZB@85004|Bifidobacteriales	201174|Actinobacteria	P	H( )-stimulated, divalent metal cation uptake system	mntH	GO:0000041,GO:0006810,GO:0006811,GO:0006812,GO:0006826,GO:0006828,GO:0006829,GO:0008150,GO:0030001,GO:0034220,GO:0034755,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071421,GO:0071577,GO:0071578,GO:0072511,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098739,GO:0099587	-	ko:K03322	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	-	Nramp
IOLKFBCL_00051	216816.GS08_02190	2.13e-173	484.0	COG2356@1|root,COG2356@2|Bacteria,2GJ38@201174|Actinobacteria,4CZCY@85004|Bifidobacteriales	201174|Actinobacteria	L	Protein of unknown function (DUF1524)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1524
IOLKFBCL_00052	216816.GS08_02185	5.08e-153	433.0	COG0656@1|root,COG0656@2|Bacteria,2GJQ7@201174|Actinobacteria,4CYUN@85004|Bifidobacteriales	201174|Actinobacteria	S	Oxidoreductase, aldo keto reductase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
IOLKFBCL_00053	762211.BSTEL_0132	0.0	1259.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4CZ04@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter, ATP-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IOLKFBCL_00054	762211.BSTEL_0132	4.02e-140	428.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4CZ04@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter, ATP-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IOLKFBCL_00055	762211.BSTEL_0133	2.59e-213	597.0	COG4585@1|root,COG4585@2|Bacteria,2GJEG@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	tcsS2	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
IOLKFBCL_00056	762211.BSTEL_0134	3.65e-119	346.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4CYQW@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
IOLKFBCL_00057	1121934.AUDX01000068_gene2395	1.27e-112	340.0	COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria,4FMJD@85023|Microbacteriaceae	201174|Actinobacteria	L	Transposase, Mutator family	tnp7109-2	-	-	ko:K07493	-	-	-	-	ko00000	-	-	-	Transposase_mut
IOLKFBCL_00058	1121934.AUDX01000068_gene2395	4.88e-62	204.0	COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria,4FMJD@85023|Microbacteriaceae	201174|Actinobacteria	L	Transposase, Mutator family	tnp7109-2	-	-	ko:K07493	-	-	-	-	ko00000	-	-	-	Transposase_mut
IOLKFBCL_00060	1437610.BREU_2323	4.39e-19	85.1	COG3547@1|root,COG3547@2|Bacteria,2GNQB@201174|Actinobacteria,4D0M5@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
IOLKFBCL_00061	216816.GS08_02175	4.69e-218	606.0	COG1609@1|root,COG1609@2|Bacteria,2GJ5Q@201174|Actinobacteria,4D040@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
IOLKFBCL_00063	216816.GS08_09320	1.71e-31	119.0	COG3464@1|root,COG3464@2|Bacteria,2IP45@201174|Actinobacteria,4D04T@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
IOLKFBCL_00065	1437609.BCAL_1105	2.53e-129	371.0	COG1136@1|root,COG1136@2|Bacteria,2IAY5@201174|Actinobacteria,4D11T@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IOLKFBCL_00066	1437609.BCAL_1106	1.43e-301	840.0	COG4652@1|root,COG4652@2|Bacteria,2ICAU@201174|Actinobacteria,4D1WE@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00067	76636.JOEC01000001_gene1069	1.95e-26	101.0	2EAM0@1|root,334PN@2|Bacteria,2GWMS@201174|Actinobacteria	201174|Actinobacteria	S	Bacteriocin (Lactococcin_972)	-	-	-	-	-	-	-	-	-	-	-	-	Lactococcin_972
IOLKFBCL_00068	158787.BSCA_0364	2.34e-34	129.0	COG2197@1|root,COG2197@2|Bacteria,2IQKB@201174|Actinobacteria,4D0VR@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
IOLKFBCL_00069	1437609.BCAL_1108	5.88e-126	378.0	COG4585@1|root,COG4585@2|Bacteria,2I01E@201174|Actinobacteria,4D2MK@85004|Bifidobacteriales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00070	1437609.BCAL_0907	3.57e-311	878.0	COG0477@1|root,COG2814@2|Bacteria,2GJF6@201174|Actinobacteria,4CZW6@85004|Bifidobacteriales	201174|Actinobacteria	U	Sugar (and other) transporter	-	-	-	ko:K02100	-	-	-	-	ko00000,ko02000	2.A.1.1.2	-	-	Sugar_tr
IOLKFBCL_00071	326426.Bbr_0415	1.21e-142	444.0	COG1132@1|root,COG4988@1|root,COG1132@2|Bacteria,COG4988@2|Bacteria,2GITR@201174|Actinobacteria,4CYSB@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147,ko:K06148,ko:K16013	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.129,3.A.1.21	-	-	ABC_membrane,ABC_tran
IOLKFBCL_00072	326426.Bbr_0415	4.6e-135	423.0	COG1132@1|root,COG4988@1|root,COG1132@2|Bacteria,COG4988@2|Bacteria,2GITR@201174|Actinobacteria,4CYSB@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147,ko:K06148,ko:K16013	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.129,3.A.1.21	-	-	ABC_membrane,ABC_tran
IOLKFBCL_00073	216816.GS08_02140	3.39e-31	111.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	araE	GO:0003674,GO:0005215,GO:0005351,GO:0005402,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008643,GO:0015075,GO:0015077,GO:0015078,GO:0015144,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0016020,GO:0022804,GO:0022857,GO:0022890,GO:0034219,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600	-	ko:K02100	-	-	-	-	ko00000,ko02000	2.A.1.1.2	-	-	Sugar_tr
IOLKFBCL_00074	216816.GS08_02135	0.0	1181.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4CZZP@85004|Bifidobacteriales	201174|Actinobacteria	I	AMP-binding enzyme	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
IOLKFBCL_00075	1416759.AYMR01000006_gene1028	1.33e-171	496.0	COG3669@1|root,COG3669@2|Bacteria,2HUEI@201174|Actinobacteria,4FRB2@85023|Microbacteriaceae	201174|Actinobacteria	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C
IOLKFBCL_00078	326426.Bbr_0263	4.15e-262	721.0	COG0477@1|root,COG2814@2|Bacteria,2HZWA@201174|Actinobacteria,4D211@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
IOLKFBCL_00079	216816.GS08_03840	1.65e-266	731.0	COG4585@1|root,COG4585@2|Bacteria,2IKQ3@201174|Actinobacteria,4D15W@85004|Bifidobacteriales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
IOLKFBCL_00080	216816.GS08_03845	1.53e-138	393.0	COG2197@1|root,COG2197@2|Bacteria,2IF55@201174|Actinobacteria,4D0XW@85004|Bifidobacteriales	201174|Actinobacteria	K	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
IOLKFBCL_00081	1193128.A200_00695	8.13e-93	285.0	COG1131@1|root,COG1131@2|Bacteria,2GJ84@201174|Actinobacteria,4D226@85004|Bifidobacteriales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990,ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC_tran
IOLKFBCL_00082	216816.GS08_03855	3.12e-175	489.0	COG1511@1|root,COG1511@2|Bacteria,2I5GR@201174|Actinobacteria,4D261@85004|Bifidobacteriales	201174|Actinobacteria	S	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
IOLKFBCL_00083	216816.GS08_03860	2.31e-166	465.0	COG1131@1|root,COG1131@2|Bacteria,2GJDP@201174|Actinobacteria,4D00Y@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IOLKFBCL_00084	216816.GS08_03865	1.22e-150	425.0	2B6EF@1|root,31ZCB@2|Bacteria,2H1Z3@201174|Actinobacteria,4D1Z5@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00086	216816.GS08_01275	1.92e-91	268.0	COG0359@1|root,COG0359@2|Bacteria,2IKX7@201174|Actinobacteria,4D0P9@85004|Bifidobacteriales	201174|Actinobacteria	J	Binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
IOLKFBCL_00087	216816.GS08_01270	2.15e-48	154.0	COG0238@1|root,COG0238@2|Bacteria,2IQ92@201174|Actinobacteria,4D103@85004|Bifidobacteriales	201174|Actinobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
IOLKFBCL_00088	216816.GS08_01265	4.24e-97	288.0	COG0629@1|root,COG0629@2|Bacteria,2GMM3@201174|Actinobacteria,4CZ5V@85004|Bifidobacteriales	201174|Actinobacteria	L	Single-stranded DNA-binding protein	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
IOLKFBCL_00089	216816.GS08_01260	2.77e-64	196.0	COG0360@1|root,COG0360@2|Bacteria,2IQHD@201174|Actinobacteria,4D10X@85004|Bifidobacteriales	201174|Actinobacteria	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0019843,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071944,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
IOLKFBCL_00090	216816.GS08_01250	6.23e-243	667.0	COG0462@1|root,COG0462@2|Bacteria,2GJ9S@201174|Actinobacteria,4CZPM@85004|Bifidobacteriales	201174|Actinobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006015,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046390,GO:0046391,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901576	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
IOLKFBCL_00091	216816.GS08_01230	6.88e-171	480.0	COG0325@1|root,COG0325@2|Bacteria,2GMRJ@201174|Actinobacteria,4CZUY@85004|Bifidobacteriales	201174|Actinobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
IOLKFBCL_00092	326426.Bbr_0249	0.0	1144.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,4CZ45@85004|Bifidobacteriales	201174|Actinobacteria	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
IOLKFBCL_00093	216816.GS08_01220	2.4e-51	163.0	COG3937@1|root,COG3937@2|Bacteria,2GS3M@201174|Actinobacteria,4D1FE@85004|Bifidobacteriales	201174|Actinobacteria	S	granule-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Phasin
IOLKFBCL_00094	216816.GS08_01215	1.98e-184	512.0	COG3442@1|root,COG3442@2|Bacteria,2GKPV@201174|Actinobacteria,4CZJ1@85004|Bifidobacteriales	201174|Actinobacteria	S	CobB/CobQ-like glutamine amidotransferase domain	cobQ2	-	-	ko:K07009	-	-	-	-	ko00000	-	-	-	GATase_3
IOLKFBCL_00095	216816.GS08_01210	0.0	937.0	COG0771@1|root,COG0771@2|Bacteria,2GK18@201174|Actinobacteria,4CYTP@85004|Bifidobacteriales	201174|Actinobacteria	M	Domain of unknown function (DUF1727)	murE	-	-	-	-	-	-	-	-	-	-	-	DUF1727,Mur_ligase_M
IOLKFBCL_00096	216816.GS08_01205	0.0	979.0	COG0305@1|root,COG0305@2|Bacteria,2GKXQ@201174|Actinobacteria,4CYY3@85004|Bifidobacteriales	201174|Actinobacteria	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
IOLKFBCL_00097	216816.GS08_01200	0.0	879.0	COG0534@1|root,COG0534@2|Bacteria,2GJE3@201174|Actinobacteria,4CZ75@85004|Bifidobacteriales	201174|Actinobacteria	V	MatE	dinF	-	-	-	-	-	-	-	-	-	-	-	MatE
IOLKFBCL_00098	216816.GS08_01195	0.0	1197.0	COG2844@1|root,COG2844@2|Bacteria,2GMKT@201174|Actinobacteria,4D07P@85004|Bifidobacteriales	201174|Actinobacteria	O	Nucleotidyltransferase domain	glnD	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008773,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0030312,GO:0044464,GO:0070566,GO:0070569,GO:0071944,GO:0140096	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,GlnD_UR_UTase,HD,NTP_transf_2
IOLKFBCL_00099	216816.GS08_01190	7.34e-72	216.0	COG0347@1|root,COG0347@2|Bacteria,2IKN1@201174|Actinobacteria,4D0VD@85004|Bifidobacteriales	201174|Actinobacteria	K	Nitrogen regulatory protein P-II	glnB	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0008150,GO:0016020,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043531,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
IOLKFBCL_00100	326426.Bbr_0241	1.59e-304	831.0	COG0004@1|root,COG0004@2|Bacteria,2GIZK@201174|Actinobacteria,4CZA0@85004|Bifidobacteriales	201174|Actinobacteria	U	Ammonium Transporter Family	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
IOLKFBCL_00101	547043.BIFPSEUDO_02894	1.78e-238	663.0	COG0552@1|root,COG0552@2|Bacteria,2GJQH@201174|Actinobacteria,4CZZX@85004|Bifidobacteriales	201174|Actinobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
IOLKFBCL_00102	518635.BIFANG_02033	3.96e-23	89.4	2B599@1|root,31Y3D@2|Bacteria,2H050@201174|Actinobacteria,4D1S0@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00103	566552.BIFCAT_00158	8.23e-62	189.0	COG3877@1|root,COG3877@2|Bacteria,2INCH@201174|Actinobacteria,4D10P@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF2089)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2089
IOLKFBCL_00104	216816.GS08_01165	5.43e-157	444.0	COG1309@1|root,COG1309@2|Bacteria,2GMBW@201174|Actinobacteria,4CYUD@85004|Bifidobacteriales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	icaR	-	-	-	-	-	-	-	-	-	-	-	TetR_N
IOLKFBCL_00105	566552.BIFCAT_00156	9.5e-239	657.0	COG0463@1|root,COG0463@2|Bacteria,2GMDK@201174|Actinobacteria,4CZIS@85004|Bifidobacteriales	201174|Actinobacteria	M	Glycosyltransferase like family 2	-	-	2.7.8.12	ko:K09809	-	-	-	-	ko00000,ko01000	-	-	-	Glycos_transf_2
IOLKFBCL_00106	566552.BIFCAT_00154	0.0	924.0	COG4690@1|root,COG4690@2|Bacteria,2GM80@201174|Actinobacteria,4CYT0@85004|Bifidobacteriales	201174|Actinobacteria	E	Peptidase family C69	-	-	-	ko:K08659	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C69
IOLKFBCL_00108	405948.SACE_0913	1.64e-12	70.5	2CM5B@1|root,32SDR@2|Bacteria,2IRBQ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00110	216816.GS08_01145	0.0	1030.0	COG0364@1|root,COG0364@2|Bacteria,2GISI@201174|Actinobacteria,4CYQM@85004|Bifidobacteriales	201174|Actinobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
IOLKFBCL_00111	216816.GS08_01140	1.24e-235	649.0	COG3429@1|root,COG3429@2|Bacteria,2GJ1H@201174|Actinobacteria,4CZI4@85004|Bifidobacteriales	201174|Actinobacteria	G	Glucose-6-phosphate dehydrogenase subunit	opcA	-	-	-	-	-	-	-	-	-	-	-	OpcA_G6PD_assem
IOLKFBCL_00112	216816.GS08_01135	2.51e-177	496.0	COG0363@1|root,COG0363@2|Bacteria,2GMQ2@201174|Actinobacteria,4CZRG@85004|Bifidobacteriales	201174|Actinobacteria	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	pgl	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:1901135,GO:1901360,GO:1901564	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
IOLKFBCL_00113	326426.Bbr_0232	0.0	953.0	COG0362@1|root,COG0362@2|Bacteria,2GJ2J@201174|Actinobacteria,4CZFG@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
IOLKFBCL_00114	216816.GS08_01125	1.76e-295	808.0	COG4905@1|root,COG4905@2|Bacteria,2IBSV@201174|Actinobacteria,4D05G@85004|Bifidobacteriales	201174|Actinobacteria	S	Putative ABC-transporter type IV	-	-	-	-	-	-	-	-	-	-	-	-	ABC_trans_CmpB
IOLKFBCL_00115	216816.GS08_01120	0.0	1439.0	COG1511@1|root,COG1511@2|Bacteria,2GKEM@201174|Actinobacteria,4CZ9R@85004|Bifidobacteriales	201174|Actinobacteria	S	YhgE Pip domain protein	-	-	-	ko:K01421	-	-	-	-	ko00000	-	-	-	ABC2_membrane,ABC2_membrane_3
IOLKFBCL_00116	216816.GS08_01115	0.0	1178.0	COG1511@1|root,COG1511@2|Bacteria,2GKEM@201174|Actinobacteria,4CZ2A@85004|Bifidobacteriales	201174|Actinobacteria	S	YhgE Pip domain protein	-	-	-	ko:K01421	-	-	-	-	ko00000	-	-	-	ABC2_membrane,ABC2_membrane_3,DUF3533
IOLKFBCL_00117	216816.GS08_01110	2.34e-135	384.0	COG1309@1|root,COG1309@2|Bacteria,2HZI8@201174|Actinobacteria,4D0IS@85004|Bifidobacteriales	201174|Actinobacteria	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_9,TetR_N
IOLKFBCL_00118	216816.GS08_01105	9.42e-111	320.0	COG3976@1|root,COG3976@2|Bacteria,2IQ4E@201174|Actinobacteria,4D0YM@85004|Bifidobacteriales	201174|Actinobacteria	S	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
IOLKFBCL_00119	216816.GS08_01100	4.85e-188	522.0	COG1136@1|root,COG1136@2|Bacteria,2GK3I@201174|Actinobacteria,4CYTA@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter, ATP-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IOLKFBCL_00120	216816.GS08_01095	3.66e-275	754.0	COG0577@1|root,COG0577@2|Bacteria,2GIRW@201174|Actinobacteria,4CZEZ@85004|Bifidobacteriales	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
IOLKFBCL_00121	216816.GS08_01090	1.66e-287	788.0	COG0577@1|root,COG0577@2|Bacteria,2I91N@201174|Actinobacteria,4CZGK@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter permease	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
IOLKFBCL_00122	216816.GS08_01085	1.28e-294	805.0	COG4393@1|root,COG4393@2|Bacteria,2GMS6@201174|Actinobacteria,4CZ19@85004|Bifidobacteriales	201174|Actinobacteria	S	Predicted membrane protein (DUF2318)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2318
IOLKFBCL_00123	216816.GS08_01080	1.43e-154	435.0	COG3470@1|root,COG3470@2|Bacteria,2GNAD@201174|Actinobacteria,4CZCG@85004|Bifidobacteriales	201174|Actinobacteria	P	Fe2+ transport protein	-	-	-	ko:K07230	-	-	-	-	ko00000,ko02000	2.A.108.2.10,2.A.108.2.4,2.A.108.2.9	-	-	Iron_transport
IOLKFBCL_00124	216816.GS08_01075	0.0	1157.0	COG0672@1|root,COG0672@2|Bacteria,2GJ22@201174|Actinobacteria,4D01C@85004|Bifidobacteriales	201174|Actinobacteria	P	Iron permease FTR1 family	-	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	FTR1
IOLKFBCL_00125	216816.GS08_01070	0.0	1063.0	2E07M@1|root,32VVG@2|Bacteria,2ICM1@201174|Actinobacteria,4D036@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00127	762211.BSTEL_1767	2.21e-218	619.0	2DPXB@1|root,333SX@2|Bacteria,2ITEG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00129	158787.BSCA_0045	1e-82	251.0	28I67@1|root,2ZYMP@2|Bacteria,2H7CN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00130	158787.BSCA_0046	1.31e-288	788.0	COG0863@1|root,COG0863@2|Bacteria,2I9U5@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	-
IOLKFBCL_00131	1437610.BREU_1226	4.49e-238	661.0	COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria,4D0ME@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K07485	-	-	-	-	ko00000	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
IOLKFBCL_00132	216816.GS08_00940	5.06e-178	498.0	COG3619@1|root,COG3619@2|Bacteria,2GKDV@201174|Actinobacteria,4CZC9@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF1275)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1275
IOLKFBCL_00133	216816.GS08_00935	8.81e-103	298.0	29ZFS@1|root,30MFB@2|Bacteria,2ISQI@201174|Actinobacteria,4D189@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00136	1437608.BBIA_0903	7.61e-228	633.0	COG1373@1|root,COG1373@2|Bacteria,2GK1Q@201174|Actinobacteria,4CZNQ@85004|Bifidobacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
IOLKFBCL_00137	1437610.BREU_1315	8e-33	124.0	COG1373@1|root,COG1373@2|Bacteria,2HVUN@201174|Actinobacteria,4CZHJ@85004|Bifidobacteriales	201174|Actinobacteria	S	AAA domain	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
IOLKFBCL_00139	216816.GS08_00920	0.0	1000.0	COG0008@1|root,COG0008@2|Bacteria,2GJJS@201174|Actinobacteria,4CZHK@85004|Bifidobacteriales	201174|Actinobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	iNJ661.Rv2992c	tRNA-synt_1c
IOLKFBCL_00140	216816.GS08_00880	3.96e-197	554.0	COG3152@1|root,COG3152@2|Bacteria,2IQHK@201174|Actinobacteria,4D0Q2@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF805)	-	-	-	-	-	-	-	-	-	-	-	-	DUF805
IOLKFBCL_00141	216816.GS08_00875	8.26e-218	600.0	COG0676@1|root,COG0676@2|Bacteria,2IIUH@201174|Actinobacteria,4CZWN@85004|Bifidobacteriales	201174|Actinobacteria	G	Aldose 1-epimerase	-	-	5.1.3.15	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	-	R02739	RC00563	ko00000,ko00001,ko01000	-	-	-	Aldose_epim
IOLKFBCL_00142	216816.GS08_00870	9.75e-202	560.0	2BR5C@1|root,32K3E@2|Bacteria,2I8T9@201174|Actinobacteria,4CZ8U@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00143	216816.GS08_00865	6.16e-159	445.0	COG0406@1|root,COG0406@2|Bacteria,2GMXF@201174|Actinobacteria,4CZ0Z@85004|Bifidobacteriales	201174|Actinobacteria	G	Phosphoglycerate mutase family	-	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	His_Phos_1
IOLKFBCL_00144	216816.GS08_00860	0.0	924.0	COG0477@1|root,COG2814@2|Bacteria,2GKMQ@201174|Actinobacteria,4CZ6D@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
IOLKFBCL_00145	216816.GS08_00855	1.83e-124	354.0	COG2246@1|root,COG2246@2|Bacteria,2HZBR@201174|Actinobacteria,4CZM6@85004|Bifidobacteriales	201174|Actinobacteria	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
IOLKFBCL_00146	216816.GS08_00850	5.49e-82	242.0	COG1942@1|root,COG1942@2|Bacteria,2II0W@201174|Actinobacteria,4D0VC@85004|Bifidobacteriales	201174|Actinobacteria	S	Macrophage migration inhibitory factor (MIF)	-	-	-	-	-	-	-	-	-	-	-	-	MIF
IOLKFBCL_00147	216816.GS08_00845	0.0	998.0	COG2759@1|root,COG2759@2|Bacteria,2GT0X@201174|Actinobacteria,4CZ7P@85004|Bifidobacteriales	201174|Actinobacteria	F	Formate-tetrahydrofolate ligase	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
IOLKFBCL_00148	216816.GS08_00840	0.0	1073.0	COG4690@1|root,COG4690@2|Bacteria,2GM80@201174|Actinobacteria,4CZI5@85004|Bifidobacteriales	201174|Actinobacteria	E	Peptidase family C69	pepD	-	-	ko:K08659	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C69
IOLKFBCL_00149	326426.Bbr_0186	1.46e-135	383.0	COG1881@1|root,COG1881@2|Bacteria,2I5K1@201174|Actinobacteria,4CZSW@85004|Bifidobacteriales	201174|Actinobacteria	S	Phosphatidylethanolamine-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
IOLKFBCL_00150	326426.Bbr_0183	0.0	1018.0	COG1080@1|root,COG1080@2|Bacteria,2GIZZ@201174|Actinobacteria,4CZ52@85004|Bifidobacteriales	201174|Actinobacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
IOLKFBCL_00151	326426.Bbr_0182	1.47e-50	160.0	COG1925@1|root,COG1925@2|Bacteria,2GQX6@201174|Actinobacteria,4D19B@85004|Bifidobacteriales	201174|Actinobacteria	G	PTS HPr component phosphorylation site	hpr	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
IOLKFBCL_00152	326426.Bbr_0181	1.6e-131	375.0	COG1609@1|root,COG1609@2|Bacteria,2GJRG@201174|Actinobacteria,4CZ05@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
IOLKFBCL_00153	326426.Bbr_0180	2.31e-259	712.0	COG0470@1|root,COG0470@2|Bacteria,2GJ8C@201174|Actinobacteria,4CZ4Y@85004|Bifidobacteriales	201174|Actinobacteria	L	DNA polymerase III	holB	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
IOLKFBCL_00154	216816.GS08_00825	3.65e-158	444.0	COG0125@1|root,COG0125@2|Bacteria,2GNTI@201174|Actinobacteria,4CYQ8@85004|Bifidobacteriales	201174|Actinobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MFS_1,MFS_3,Thymidylate_kin
IOLKFBCL_00155	216816.GS08_00820	0.0	1880.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,2GJU7@201174|Actinobacteria,4CZ85@85004|Bifidobacteriales	201174|Actinobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010605,GO:0016020,GO:0016853,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0040007,GO:0043086,GO:0043167,GO:0043169,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060700,GO:0060701,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0140097	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
IOLKFBCL_00156	216816.GS08_00815	1.81e-212	591.0	COG0671@1|root,COG0671@2|Bacteria,2HIXE@201174|Actinobacteria,4CYS6@85004|Bifidobacteriales	201174|Actinobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
IOLKFBCL_00157	216816.GS08_00810	0.0	1229.0	COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria,4CZQZ@85004|Bifidobacteriales	201174|Actinobacteria	M	Transglycosylase	pbp5	-	-	-	-	-	-	-	-	-	-	-	Transgly,Transpeptidase
IOLKFBCL_00158	326426.Bbr_0175	0.0	1248.0	COG0119@1|root,COG0119@2|Bacteria,2GISX@201174|Actinobacteria,4CZYW@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	GO:0000287,GO:0003674,GO:0003824,GO:0003852,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0019752,GO:0030145,GO:0030955,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0046912,GO:0046914,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
IOLKFBCL_00159	216816.GS08_00800	0.0	1056.0	COG1409@1|root,COG1409@2|Bacteria,2GNKK@201174|Actinobacteria,4CZMC@85004|Bifidobacteriales	201174|Actinobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
IOLKFBCL_00160	216816.GS08_00795	1.25e-147	415.0	2C7PT@1|root,2ZXN2@2|Bacteria,2GM64@201174|Actinobacteria,4CYPY@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00161	216816.GS08_00790	2.54e-267	731.0	COG0136@1|root,COG0136@2|Bacteria,2GJJ8@201174|Actinobacteria,4CZPY@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	GO:0003674,GO:0003824,GO:0004073,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3708c	Semialdhyde_dh,Semialdhyde_dhC
IOLKFBCL_00162	216816.GS08_00785	1.17e-125	358.0	COG0527@1|root,COG0527@2|Bacteria,2GN0G@201174|Actinobacteria,4D00P@85004|Bifidobacteriales	201174|Actinobacteria	E	ACT domain	ask	GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
IOLKFBCL_00163	326426.Bbr_0147	3.35e-169	474.0	COG0527@1|root,COG0527@2|Bacteria,2GN0G@201174|Actinobacteria,4CYSD@85004|Bifidobacteriales	201174|Actinobacteria	E	Amino acid kinase family	ask	GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
IOLKFBCL_00164	1120941.AUBL01000004_gene1708	1.06e-64	210.0	COG1373@1|root,COG1373@2|Bacteria,2GK4E@201174|Actinobacteria,4D3U8@85005|Actinomycetales	201174|Actinobacteria	S	Psort location Cytoplasmic, score	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
IOLKFBCL_00165	216816.GS08_00775	8.03e-257	706.0	COG3764@1|root,COG3764@2|Bacteria,2GNWT@201174|Actinobacteria,4CZMM@85004|Bifidobacteriales	201174|Actinobacteria	M	Sortase family	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
IOLKFBCL_00166	216816.GS08_00770	1.93e-139	394.0	COG0353@1|root,COG0353@2|Bacteria,2GJY0@201174|Actinobacteria,4CZRI@85004|Bifidobacteriales	201174|Actinobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
IOLKFBCL_00167	216816.GS08_00765	0.0	1408.0	COG2812@1|root,COG2812@2|Bacteria,2GJKA@201174|Actinobacteria,4CZMY@85004|Bifidobacteriales	201174|Actinobacteria	L	DNA polymerase III subunit gamma tau	dnaX	GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
IOLKFBCL_00168	216816.GS08_00760	9.91e-137	387.0	COG1309@1|root,COG1309@2|Bacteria,2GND5@201174|Actinobacteria,4CZUU@85004|Bifidobacteriales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
IOLKFBCL_00169	216816.GS08_00755	4.26e-272	744.0	COG1597@1|root,COG1597@2|Bacteria,2GK3P@201174|Actinobacteria,4CZ1S@85004|Bifidobacteriales	201174|Actinobacteria	I	Diacylglycerol kinase catalytic domain protein	-	-	2.7.1.107	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_cat
IOLKFBCL_00170	216816.GS08_00750	4.43e-70	212.0	2DRBM@1|root,33B4F@2|Bacteria,2HZRZ@201174|Actinobacteria,4D1G6@85004|Bifidobacteriales	201174|Actinobacteria	S	TIGRFAM helicase secretion neighborhood TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Tad
IOLKFBCL_00171	216816.GS08_00740	3.54e-53	167.0	2EHCF@1|root,33B4A@2|Bacteria,2GR72@201174|Actinobacteria,4D1FR@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF4244)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4244
IOLKFBCL_00172	216816.GS08_00735	1.63e-131	374.0	COG2064@1|root,COG2064@2|Bacteria,2I2FP@201174|Actinobacteria,4D16W@85004|Bifidobacteriales	201174|Actinobacteria	NU	Type II secretion system (T2SS), protein F	-	-	-	-	-	-	-	-	-	-	-	-	T2SSF
IOLKFBCL_00173	216816.GS08_00730	1.72e-135	385.0	COG4965@1|root,COG4965@2|Bacteria,2GRXU@201174|Actinobacteria,4D1A3@85004|Bifidobacteriales	201174|Actinobacteria	U	Type ii secretion system	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	-
IOLKFBCL_00174	216816.GS08_00725	1.12e-245	676.0	COG4962@1|root,COG4962@2|Bacteria,2GKKJ@201174|Actinobacteria,4CZF2@85004|Bifidobacteriales	201174|Actinobacteria	U	Type II IV secretion system protein	cpaF	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
IOLKFBCL_00175	216816.GS08_00720	7.3e-120	345.0	COG0455@1|root,COG0455@2|Bacteria,2HZIH@201174|Actinobacteria,4D0JG@85004|Bifidobacteriales	201174|Actinobacteria	D	bacterial-type flagellum organization	-	-	-	-	-	-	-	-	-	-	-	-	ParA
IOLKFBCL_00176	216816.GS08_00710	2.59e-171	478.0	COG0586@1|root,COG0586@2|Bacteria,2GKGR@201174|Actinobacteria,4CZ7Y@85004|Bifidobacteriales	201174|Actinobacteria	S	SNARE associated Golgi protein	dedA1	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
IOLKFBCL_00177	216816.GS08_00680	5.91e-159	445.0	COG0637@1|root,COG0637@2|Bacteria,2GJNG@201174|Actinobacteria,4CYZV@85004|Bifidobacteriales	201174|Actinobacteria	S	HAD hydrolase, family IA, variant 3	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
IOLKFBCL_00178	326426.Bbr_0129	9.22e-181	504.0	COG1028@1|root,COG1028@2|Bacteria,2GIX2@201174|Actinobacteria,4D0FH@85004|Bifidobacteriales	201174|Actinobacteria	IQ	Oxidoreductase, short chain dehydrogenase reductase family protein	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
IOLKFBCL_00179	1437610.BREU_1927	3.35e-291	804.0	COG1012@1|root,COG1012@2|Bacteria,2HZAQ@201174|Actinobacteria,4CZDA@85004|Bifidobacteriales	201174|Actinobacteria	C	Acyl-CoA reductase (LuxC)	-	-	-	-	-	-	-	-	-	-	-	-	LuxC
IOLKFBCL_00180	1437610.BREU_1928	6.13e-263	721.0	COG1541@1|root,COG1541@2|Bacteria,2HZHX@201174|Actinobacteria,4D0HV@85004|Bifidobacteriales	201174|Actinobacteria	H	long-chain-fatty-acid--luciferin-component ligase, acyl-protein synthase	-	-	-	-	-	-	-	-	-	-	-	-	LuxE
IOLKFBCL_00181	1437610.BREU_1929	2.88e-270	748.0	COG2233@1|root,COG2233@2|Bacteria,2GV9H@201174|Actinobacteria,4CZYX@85004|Bifidobacteriales	201174|Actinobacteria	F	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	Xan_ur_permease
IOLKFBCL_00182	326426.Bbr_0127	5.09e-128	365.0	COG0789@1|root,COG0789@2|Bacteria,2IQJ4@201174|Actinobacteria,4D0Q7@85004|Bifidobacteriales	201174|Actinobacteria	K	transcriptional regulator, MerR family	hspR	GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
IOLKFBCL_00183	216816.GS08_00670	3.79e-231	637.0	COG0484@1|root,COG0484@2|Bacteria,2GJKK@201174|Actinobacteria,4CZ68@85004|Bifidobacteriales	201174|Actinobacteria	O	DnaJ molecular chaperone homology domain	dnaJ	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
IOLKFBCL_00184	1437609.BCAL_2359	2.8e-95	284.0	COG0576@1|root,COG0576@2|Bacteria,2GP4F@201174|Actinobacteria,4CZJ6@85004|Bifidobacteriales	201174|Actinobacteria	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0017076,GO:0030234,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0044464,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0071496,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
IOLKFBCL_00185	216816.GS08_00660	0.0	1134.0	COG0443@1|root,COG0443@2|Bacteria,2GJTY@201174|Actinobacteria,4CZDX@85004|Bifidobacteriales	201174|Actinobacteria	O	Heat shock 70 kDa protein	dnaK	GO:0000302,GO:0000303,GO:0000305,GO:0001968,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009893,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016310,GO:0019222,GO:0019538,GO:0019899,GO:0030112,GO:0030162,GO:0030312,GO:0030313,GO:0031323,GO:0031325,GO:0031975,GO:0031982,GO:0032268,GO:0032270,GO:0033554,GO:0034599,GO:0034614,GO:0035375,GO:0036211,GO:0040007,GO:0042221,GO:0042603,GO:0043170,GO:0043226,GO:0043227,GO:0043230,GO:0043388,GO:0043412,GO:0044044,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046677,GO:0046688,GO:0046777,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051098,GO:0051099,GO:0051101,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070613,GO:0070887,GO:0071450,GO:0071451,GO:0071704,GO:0071944,GO:0080090,GO:0097691,GO:1901564,GO:1901700,GO:1901701,GO:1903317,GO:1903319,GO:1903561,GO:2000677,GO:2000679	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
IOLKFBCL_00186	1680.BADO_1460	0.0	1102.0	COG1785@1|root,COG1785@2|Bacteria,2GM8A@201174|Actinobacteria,4CYZF@85004|Bifidobacteriales	201174|Actinobacteria	P	Alkaline phosphatase homologues	strK	-	3.1.3.1,3.1.3.39	ko:K01077,ko:K04342	ko00521,ko00730,ko00790,ko01100,ko01130,ko02020,map00521,map00730,map00790,map01100,map01130,map02020	M00126	R02135,R02228,R04620	RC00017,RC00078	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
IOLKFBCL_00187	1437610.BREU_0342	0.0	1460.0	COG1640@1|root,COG1640@2|Bacteria,2GM5Z@201174|Actinobacteria,4CZ0F@85004|Bifidobacteriales	201174|Actinobacteria	G	4-alpha-glucanotransferase	malQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
IOLKFBCL_00188	1437610.BREU_0341	4.02e-238	655.0	COG1609@1|root,COG1609@2|Bacteria,2GJBJ@201174|Actinobacteria,4CZ1Y@85004|Bifidobacteriales	201174|Actinobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
IOLKFBCL_00189	216816.GS08_00585	0.0	1251.0	COG0366@1|root,COG0366@2|Bacteria,2GKS4@201174|Actinobacteria,4CZ1E@85004|Bifidobacteriales	201174|Actinobacteria	G	Alpha-amylase domain	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	Alpha-amylase,DUF3459
IOLKFBCL_00190	216816.GS08_00570	5.06e-260	711.0	COG0059@1|root,COG0059@2|Bacteria,2GKXA@201174|Actinobacteria,4CZBR@85004|Bifidobacteriales	201174|Actinobacteria	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008677,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
IOLKFBCL_00191	218140.BPSY_0937	1.09e-74	229.0	COG1268@1|root,COG1268@2|Bacteria,2GJ53@201174|Actinobacteria,4D0BB@85004|Bifidobacteriales	201174|Actinobacteria	S	BioY family	bioY	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
IOLKFBCL_00192	327277.JHAL01000002_gene49	4.04e-91	275.0	COG1122@1|root,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria,4D23W@85004|Bifidobacteriales	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	bioM	-	-	ko:K16784	ko02010,map02010	M00581	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25.1	-	-	ABC_tran
IOLKFBCL_00193	327277.JHAL01000002_gene48	4.44e-65	206.0	COG0619@1|root,COG0619@2|Bacteria,2IQMQ@201174|Actinobacteria,4D23J@85004|Bifidobacteriales	201174|Actinobacteria	P	Cobalt transport protein	bioN	-	-	ko:K16783	ko02010,map02010	M00581	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25.1	-	-	CbiQ
IOLKFBCL_00194	216816.GS08_00565	8.38e-259	708.0	COG0059@1|root,COG0059@2|Bacteria,2GKXA@201174|Actinobacteria,4CZBR@85004|Bifidobacteriales	201174|Actinobacteria	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008677,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
IOLKFBCL_00195	216816.GS08_00560	0.0	886.0	COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria,4CYY8@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
IOLKFBCL_00197	326426.Bbr_0101	0.0	979.0	COG2211@1|root,COG2211@2|Bacteria,2GJZG@201174|Actinobacteria,4CZ93@85004|Bifidobacteriales	201174|Actinobacteria	G	Transporter major facilitator family protein	scrT	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_2
IOLKFBCL_00198	216816.GS08_00550	0.0	1029.0	COG0366@1|root,COG0366@2|Bacteria,2GNEC@201174|Actinobacteria,4CZ4T@85004|Bifidobacteriales	201174|Actinobacteria	G	Domain of unknown function (DUF1964)	gtfA	-	2.4.1.7	ko:K00690	ko00500,map00500	-	R00803	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF1964
IOLKFBCL_00199	216816.GS08_00545	3.83e-256	702.0	COG1609@1|root,COG1609@2|Bacteria,2GMHV@201174|Actinobacteria,4CZ3G@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K03484	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
IOLKFBCL_00200	216816.GS08_00515	5.18e-81	241.0	COG0239@1|root,COG0239@2|Bacteria,2IC26@201174|Actinobacteria,4D14T@85004|Bifidobacteriales	201174|Actinobacteria	U	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
IOLKFBCL_00201	547043.BIFPSEUDO_04069	4.08e-199	560.0	COG0239@1|root,COG0239@2|Bacteria,2IC26@201174|Actinobacteria,4D0RK@85004|Bifidobacteriales	201174|Actinobacteria	U	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
IOLKFBCL_00202	216816.GS08_00505	0.0	977.0	COG0038@1|root,COG0569@1|root,COG0038@2|Bacteria,COG0569@2|Bacteria,2GPPN@201174|Actinobacteria,4CZQR@85004|Bifidobacteriales	201174|Actinobacteria	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	TrkA_C,Voltage_CLC
IOLKFBCL_00203	216816.GS08_00500	9.71e-317	861.0	COG0104@1|root,COG0104@2|Bacteria,2GMP4@201174|Actinobacteria,4CZ0U@85004|Bifidobacteriales	201174|Actinobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
IOLKFBCL_00204	158787.BSCA_0143	7.23e-263	720.0	COG0191@1|root,COG0191@2|Bacteria,2GM5P@201174|Actinobacteria,4CZJI@85004|Bifidobacteriales	201174|Actinobacteria	G	Fructose-bisphosphate aldolase class-II	fbaA	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
IOLKFBCL_00205	216816.GS08_00475	2.85e-152	429.0	COG3663@1|root,COG3663@2|Bacteria,2GNS5@201174|Actinobacteria,4D132@85004|Bifidobacteriales	201174|Actinobacteria	L	Uracil DNA glycosylase superfamily	mug	-	3.2.2.28	ko:K03649	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
IOLKFBCL_00206	216816.GS08_00470	7.78e-262	719.0	COG0477@1|root,COG2814@2|Bacteria,2HZWA@201174|Actinobacteria,4D211@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
IOLKFBCL_00208	742742.HMPREF9452_02057	1.55e-125	414.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	3.2.1.4	ko:K01179,ko:K21449	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko02000	1.B.40.2	GH5,GH9	-	DUF1929,Laminin_G_3,Metallophos
IOLKFBCL_00209	216816.GS08_00460	5.53e-205	570.0	COG0501@1|root,COG0501@2|Bacteria,2GMJF@201174|Actinobacteria,4CYVY@85004|Bifidobacteriales	201174|Actinobacteria	O	Belongs to the peptidase M48B family	htpX	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
IOLKFBCL_00210	216816.GS08_00455	0.0	928.0	COG0493@1|root,COG0493@2|Bacteria,2GJ4A@201174|Actinobacteria,4CZIT@85004|Bifidobacteriales	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	fprA	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	Pyr_redox_2
IOLKFBCL_00211	398513.BBNG_01398	4.01e-260	729.0	COG4932@1|root,COG4932@2|Bacteria,2IMAM@201174|Actinobacteria,4D2UC@85004|Bifidobacteriales	201174|Actinobacteria	M	LPXTG cell wall anchor motif	-	-	-	-	-	-	-	-	-	-	-	-	GramPos_pilinBB,Gram_pos_anchor
IOLKFBCL_00212	398513.BBNG_01395	6.26e-125	369.0	COG3764@1|root,COG3764@2|Bacteria,2GNWT@201174|Actinobacteria,4CZMM@85004|Bifidobacteriales	201174|Actinobacteria	M	Sortase family	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
IOLKFBCL_00213	1437609.BCAL_2301	1.81e-116	342.0	COG0829@1|root,COG0829@2|Bacteria,2HZI9@201174|Actinobacteria,4D0IT@85004|Bifidobacteriales	201174|Actinobacteria	O	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter	ureD	-	-	ko:K03190	-	-	-	-	ko00000	-	-	-	UreD
IOLKFBCL_00214	1437609.BCAL_2302	3.67e-127	363.0	COG0378@1|root,COG0378@2|Bacteria,2GNUV@201174|Actinobacteria,4D0FK@85004|Bifidobacteriales	201174|Actinobacteria	KO	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG	ureG	-	-	ko:K03189	-	-	-	-	ko00000	-	-	-	cobW
IOLKFBCL_00215	1437609.BCAL_2303	1.13e-101	305.0	COG0830@1|root,COG0830@2|Bacteria,2HZCE@201174|Actinobacteria,4CZRB@85004|Bifidobacteriales	201174|Actinobacteria	J	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter	ureF	-	-	ko:K03188	-	-	-	-	ko00000	-	-	-	UreF
IOLKFBCL_00216	1437609.BCAL_2304	9.64e-113	327.0	COG2371@1|root,COG2371@2|Bacteria,2IDSE@201174|Actinobacteria,4D05Y@85004|Bifidobacteriales	201174|Actinobacteria	O	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly	ureE	-	-	ko:K03187	-	-	-	-	ko00000	-	-	-	UreE_C
IOLKFBCL_00217	1437609.BCAL_2297	0.0	1050.0	COG0804@1|root,COG0804@2|Bacteria,2GM7X@201174|Actinobacteria,4D0G9@85004|Bifidobacteriales	201174|Actinobacteria	E	Urease alpha-subunit, N-terminal domain	ureC	-	3.5.1.5	ko:K01427,ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Urease_alpha
IOLKFBCL_00218	158787.BSCA_0625	6.14e-123	355.0	COG0831@1|root,COG0832@1|root,COG0831@2|Bacteria,COG0832@2|Bacteria,2IKNA@201174|Actinobacteria,4CZA2@85004|Bifidobacteriales	201174|Actinobacteria	E	Urease, gamma subunit	ureA	-	3.5.1.5	ko:K01430,ko:K14048	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Urease_beta,Urease_gamma
IOLKFBCL_00219	1444306.JFZC01000038_gene2861	2.66e-138	403.0	COG2042@1|root,COG3376@2|Bacteria,1TSSI@1239|Firmicutes,4HEUV@91061|Bacilli	91061|Bacilli	U	Belongs to the NiCoT transporter (TC 2.A.52) family	hoxN	-	-	ko:K07241	-	-	-	-	ko00000,ko02000	2.A.52.1	-	-	NicO
IOLKFBCL_00220	1437609.BCAL_2282	8.34e-128	367.0	COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria,4D0EB@85004|Bifidobacteriales	201174|Actinobacteria	E	ABC transporter	urtE	-	-	ko:K11963	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	ABC_tran
IOLKFBCL_00221	158787.BSCA_0633	4.04e-147	422.0	COG4674@1|root,COG4674@2|Bacteria,2GP3Y@201174|Actinobacteria,4D03S@85004|Bifidobacteriales	201174|Actinobacteria	S	Branched-chain amino acid ATP-binding cassette transporter	urtD	-	-	ko:K11962	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	ABC_tran,BCA_ABC_TP_C
IOLKFBCL_00222	1437609.BCAL_2280	2.7e-203	570.0	COG4177@1|root,COG4177@2|Bacteria,2GNZK@201174|Actinobacteria,4CZJ2@85004|Bifidobacteriales	201174|Actinobacteria	U	Branched-chain amino acid transport system / permease component	urtC	-	-	ko:K01998,ko:K11961	ko02010,ko02024,map02010,map02024	M00237,M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4,3.A.1.4.4,3.A.1.4.5	-	-	BPD_transp_2
IOLKFBCL_00223	1437609.BCAL_2279	7.88e-165	466.0	COG0559@1|root,COG0559@2|Bacteria,2GKAR@201174|Actinobacteria,4D0FD@85004|Bifidobacteriales	201174|Actinobacteria	U	Branched-chain amino acid transport system / permease component	urtB	-	-	ko:K11960	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	BPD_transp_2
IOLKFBCL_00224	158787.BSCA_0636	2.77e-247	686.0	COG0683@1|root,COG0683@2|Bacteria,2I8ME@201174|Actinobacteria,4D087@85004|Bifidobacteriales	201174|Actinobacteria	E	Receptor family ligand binding region	urtA	-	-	ko:K11959	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	Peripla_BP_5
IOLKFBCL_00225	216816.GS08_00445	0.0	1123.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4CZ4F@85004|Bifidobacteriales	201174|Actinobacteria	P	E1-E2 ATPase	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hemerythrin,Hydrolase
IOLKFBCL_00226	216816.GS08_00440	0.0	984.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4CZAP@85004|Bifidobacteriales	201174|Actinobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	degP	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
IOLKFBCL_00227	216816.GS08_00435	0.0	889.0	COG0343@1|root,COG0343@2|Bacteria,2GMWY@201174|Actinobacteria,4CZNX@85004|Bifidobacteriales	201174|Actinobacteria	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
IOLKFBCL_00230	1211817.CCAT010000062_gene3991	4.84e-72	224.0	COG0693@1|root,COG0693@2|Bacteria,1TPJK@1239|Firmicutes,24BTV@186801|Clostridia,36DI2@31979|Clostridiaceae	186801|Clostridia	S	PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
IOLKFBCL_00231	1680.BADO_0041	4.14e-93	273.0	COG0071@1|root,COG0071@2|Bacteria,2HZHR@201174|Actinobacteria,4D0H9@85004|Bifidobacteriales	201174|Actinobacteria	O	Hsp20/alpha crystallin family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
IOLKFBCL_00232	326426.Bbr_0087	8.94e-163	460.0	COG1272@1|root,COG1272@2|Bacteria,2HRAC@201174|Actinobacteria,4D0D6@85004|Bifidobacteriales	201174|Actinobacteria	S	Haemolysin-III related	-	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
IOLKFBCL_00233	216816.GS08_00410	5.86e-68	206.0	COG0393@1|root,COG0393@2|Bacteria,2IQNY@201174|Actinobacteria,4D0ZM@85004|Bifidobacteriales	201174|Actinobacteria	S	Putative heavy-metal-binding	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
IOLKFBCL_00234	216816.GS08_00405	1.64e-98	285.0	COG0494@1|root,COG0494@2|Bacteria,2I2GY@201174|Actinobacteria,4D0UJ@85004|Bifidobacteriales	201174|Actinobacteria	L	NUDIX domain	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
IOLKFBCL_00235	326426.Bbr_0085	0.0	2124.0	COG1061@1|root,COG3886@1|root,COG1061@2|Bacteria,COG3886@2|Bacteria,2GJ4Y@201174|Actinobacteria,4CZNN@85004|Bifidobacteriales	201174|Actinobacteria	KL	Domain of unknown function (DUF3427)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3427,Helicase_C,PLDc_2,ResIII
IOLKFBCL_00236	216816.GS08_00395	1.53e-208	576.0	COG1215@1|root,COG1215@2|Bacteria,2I2IF@201174|Actinobacteria,4CYW6@85004|Bifidobacteriales	201174|Actinobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
IOLKFBCL_00237	216816.GS08_00390	5.55e-143	403.0	COG3467@1|root,COG3467@2|Bacteria,2IGUA@201174|Actinobacteria,4D0SF@85004|Bifidobacteriales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
IOLKFBCL_00238	216816.GS08_00385	6.74e-245	671.0	COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,2GJ1S@201174|Actinobacteria,4CZXJ@85004|Bifidobacteriales	201174|Actinobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008113,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0016491,GO:0016667,GO:0016671,GO:0020012,GO:0030682,GO:0033744,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0075136	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
IOLKFBCL_00239	216816.GS08_00380	0.0	1657.0	COG2898@1|root,COG2898@2|Bacteria,2GM2C@201174|Actinobacteria,4CYW5@85004|Bifidobacteriales	201174|Actinobacteria	S	Uncharacterised conserved protein (DUF2156)	lysX	-	-	-	-	-	-	-	-	-	-	-	DUF2156,Rhomboid
IOLKFBCL_00240	216816.GS08_00375	1.47e-285	788.0	COG0627@1|root,COG0627@2|Bacteria,2GP6Q@201174|Actinobacteria,4CYXF@85004|Bifidobacteriales	201174|Actinobacteria	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
IOLKFBCL_00241	216816.GS08_00365	4.22e-188	527.0	COG0697@1|root,COG0697@2|Bacteria,2GM6M@201174|Actinobacteria,4CZPP@85004|Bifidobacteriales	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
IOLKFBCL_00242	216816.GS08_00335	3.04e-262	718.0	COG2267@1|root,COG2267@2|Bacteria,2HZ9U@201174|Actinobacteria,4CZ5E@85004|Bifidobacteriales	201174|Actinobacteria	I	Serine aminopeptidase, S33	pldB	-	3.1.1.5	ko:K01048	ko00564,map00564	-	-	-	ko00000,ko00001,ko01000	-	-	-	Hydrolase_4
IOLKFBCL_00243	216816.GS08_00330	0.0	1528.0	COG1506@1|root,COG1506@2|Bacteria,2GJ6A@201174|Actinobacteria,4CZAE@85004|Bifidobacteriales	201174|Actinobacteria	E	Dipeptidyl peptidase IV (DPP IV) N-terminal region	pepX	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,PD40,Peptidase_S9
IOLKFBCL_00244	216816.GS08_00325	6.12e-166	464.0	COG1716@1|root,COG1716@2|Bacteria,2GNU2@201174|Actinobacteria,4CYUI@85004|Bifidobacteriales	201174|Actinobacteria	T	Protein of unknown function (DUF2662)	fhaA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA,Yop-YscD_cpl
IOLKFBCL_00245	1437610.BREU_0878	1.73e-82	248.0	COG1716@1|root,COG1716@2|Bacteria,2GKA7@201174|Actinobacteria,4D0RN@85004|Bifidobacteriales	201174|Actinobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	fhaB	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
IOLKFBCL_00246	216816.GS08_00315	0.0	919.0	COG0631@1|root,COG0631@2|Bacteria,2GJ3M@201174|Actinobacteria,4CZDN@85004|Bifidobacteriales	201174|Actinobacteria	T	Sigma factor PP2C-like phosphatases	pstP	GO:0000287,GO:0001932,GO:0001933,GO:0003674,GO:0003824,GO:0004647,GO:0004721,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006469,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009892,GO:0009987,GO:0010563,GO:0010605,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019220,GO:0019222,GO:0019538,GO:0030145,GO:0030312,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0032268,GO:0032269,GO:0033673,GO:0036211,GO:0042325,GO:0042326,GO:0042578,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043392,GO:0043412,GO:0043549,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0045859,GO:0045936,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051098,GO:0051100,GO:0051101,GO:0051171,GO:0051172,GO:0051174,GO:0051246,GO:0051248,GO:0051338,GO:0051348,GO:0060255,GO:0065007,GO:0065009,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
IOLKFBCL_00247	216816.GS08_00310	0.0	913.0	COG0772@1|root,COG0772@2|Bacteria,2GJTI@201174|Actinobacteria,4CZ67@85004|Bifidobacteriales	201174|Actinobacteria	D	Belongs to the SEDS family	rodA	GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
IOLKFBCL_00248	216816.GS08_00305	0.0	908.0	COG0768@1|root,COG0768@2|Bacteria,2GJUQ@201174|Actinobacteria,4CYTI@85004|Bifidobacteriales	201174|Actinobacteria	M	penicillin-binding protein	pbpA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
IOLKFBCL_00249	216816.GS08_00300	3.11e-221	610.0	COG0515@1|root,COG0515@2|Bacteria,2GMPZ@201174|Actinobacteria,4CYUK@85004|Bifidobacteriales	201174|Actinobacteria	T	Protein tyrosine kinase	pknA	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
IOLKFBCL_00250	216816.GS08_00295	0.0	1179.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4CZFU@85004|Bifidobacteriales	201174|Actinobacteria	KLT	Protein tyrosine kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
IOLKFBCL_00251	216816.GS08_00290	7.5e-153	429.0	COG0512@1|root,COG0512@2|Bacteria,2GJUX@201174|Actinobacteria,4D09E@85004|Bifidobacteriales	201174|Actinobacteria	EH	para-aminobenzoate synthase glutamine amidotransferase component II	trpG	GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
IOLKFBCL_00252	216816.GS08_00285	1.5e-297	811.0	COG3764@1|root,COG3764@2|Bacteria,2GKT6@201174|Actinobacteria,4CYZ5@85004|Bifidobacteriales	201174|Actinobacteria	M	Sortase family	srtB	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
IOLKFBCL_00253	216816.GS08_00280	1.64e-156	442.0	COG3879@1|root,COG3879@2|Bacteria,2GJ9Y@201174|Actinobacteria,4CZ1A@85004|Bifidobacteriales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF881)	-	-	-	-	-	-	-	-	-	-	-	-	DUF881
IOLKFBCL_00254	216816.GS08_00275	3.01e-106	306.0	2E4NY@1|root,32ZHR@2|Bacteria,2GQPW@201174|Actinobacteria,4D0ZH@85004|Bifidobacteriales	201174|Actinobacteria	D	Involved in cell division	crgA	-	-	-	-	-	-	-	-	-	-	-	CrgA
IOLKFBCL_00255	216816.GS08_00270	9.63e-162	454.0	COG0705@1|root,COG0705@2|Bacteria,2GJYG@201174|Actinobacteria,4CZJ0@85004|Bifidobacteriales	201174|Actinobacteria	S	Rhomboid family	gluP	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid,zf-B_box
IOLKFBCL_00256	216816.GS08_00265	2.06e-46	149.0	2BFAJ@1|root,3293I@2|Bacteria,2ISGB@201174|Actinobacteria,4D185@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00257	326426.Bbr_0060	0.0	1630.0	COG0058@1|root,COG0058@2|Bacteria,2GIVZ@201174|Actinobacteria,4CZ3V@85004|Bifidobacteriales	201174|Actinobacteria	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
IOLKFBCL_00258	216816.GS08_00255	4.68e-99	287.0	COG3255@1|root,COG3255@2|Bacteria,2IQBF@201174|Actinobacteria,4D10H@85004|Bifidobacteriales	201174|Actinobacteria	I	Sterol carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_C,MDMPI_N
IOLKFBCL_00259	216816.GS08_00250	5.79e-306	837.0	COG0477@1|root,COG0477@2|Bacteria,2I3AP@201174|Actinobacteria,4D0YC@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
IOLKFBCL_00260	216816.GS08_00245	2.63e-265	728.0	COG4585@1|root,COG4585@2|Bacteria,2IC0A@201174|Actinobacteria,4D04K@85004|Bifidobacteriales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00261	216816.GS08_00240	5.37e-146	412.0	COG2197@1|root,COG2197@2|Bacteria,2IF55@201174|Actinobacteria,4D0XW@85004|Bifidobacteriales	201174|Actinobacteria	K	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
IOLKFBCL_00262	326426.Bbr_0058	4.19e-58	182.0	2EGRW@1|root,32FNP@2|Bacteria,2HZNH@201174|Actinobacteria,4D120@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3073)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3073
IOLKFBCL_00263	326426.Bbr_0057	4.29e-254	697.0	COG0180@1|root,COG0180@2|Bacteria,2GJ9A@201174|Actinobacteria,4CYXM@85004|Bifidobacteriales	201174|Actinobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
IOLKFBCL_00264	1437608.BBIA_2536	9.06e-136	394.0	COG2253@1|root,COG2253@2|Bacteria,2IHDQ@201174|Actinobacteria,4D0UC@85004|Bifidobacteriales	201174|Actinobacteria	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
IOLKFBCL_00265	1437608.BBIA_2535	8.11e-72	221.0	COG5340@1|root,COG5340@2|Bacteria,2IMTJ@201174|Actinobacteria,4D150@85004|Bifidobacteriales	201174|Actinobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00266	1680.BADO_0016	0.0	988.0	COG0591@1|root,COG0591@2|Bacteria,2I041@201174|Actinobacteria,4CZS2@85004|Bifidobacteriales	201174|Actinobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21.2	-	-	SSF
IOLKFBCL_00267	518635.BIFANG_03609	1.65e-120	363.0	COG0477@1|root,COG2814@2|Bacteria,2I8QF@201174|Actinobacteria,4CZF1@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
IOLKFBCL_00268	1120959.ATXF01000011_gene203	1.48e-14	76.3	COG0640@1|root,COG0640@2|Bacteria,2II9U@201174|Actinobacteria,4FPUJ@85023|Microbacteriaceae	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
IOLKFBCL_00269	216816.GS08_00210	0.0	1217.0	COG2966@1|root,COG3610@1|root,COG2966@2|Bacteria,COG3610@2|Bacteria,2HZ8C@201174|Actinobacteria,4CYR2@85004|Bifidobacteriales	201174|Actinobacteria	S	Threonine/Serine exporter, ThrE	-	-	-	-	-	-	-	-	-	-	-	-	ThrE,ThrE_2
IOLKFBCL_00270	216816.GS08_00205	0.0	1823.0	COG2352@1|root,COG2352@2|Bacteria,2GKDB@201174|Actinobacteria,4CZS0@85004|Bifidobacteriales	201174|Actinobacteria	H	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
IOLKFBCL_00272	649743.HMPREF0972_01148	0.0	948.0	COG3409@1|root,COG3409@2|Bacteria,2GMEN@201174|Actinobacteria,4D3K2@85005|Actinomycetales	201174|Actinobacteria	M	Domain of unknown function (DUF1906)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1906,PG_binding_1
IOLKFBCL_00275	566552.BIFCAT_00531	1.92e-141	414.0	28K0U@1|root,2Z9QP@2|Bacteria,2I8TZ@201174|Actinobacteria,4D22X@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Mrr_cat
IOLKFBCL_00277	566552.BIFCAT_00533	4.51e-198	576.0	COG0419@1|root,COG0419@2|Bacteria	2|Bacteria	L	ATPase involved in DNA repair	-	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_11,AAA_12,AAA_13,AAA_15,AAA_23,DUF3732,SMC_N
IOLKFBCL_00278	216816.GS08_00180	5.6e-45	145.0	COG2352@1|root,COG2352@2|Bacteria,2GKDB@201174|Actinobacteria,4CZS0@85004|Bifidobacteriales	201174|Actinobacteria	H	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
IOLKFBCL_00280	216816.GS08_00195	2.38e-83	254.0	COG3409@1|root,COG3409@2|Bacteria,2GMEN@201174|Actinobacteria,4D1HF@85004|Bifidobacteriales	201174|Actinobacteria	M	Domain of unknown function (DUF1906)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1906,PG_binding_1
IOLKFBCL_00281	864069.MicloDRAFT_00031430	2.49e-186	547.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2TQP0@28211|Alphaproteobacteria,1JSFR@119045|Methylobacteriaceae	28211|Alphaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032,ko:K13892	ko02010,ko02024,map02010,map02024	M00239,M00348	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.11	-	-	ABC_tran,oligo_HPY
IOLKFBCL_00282	272562.CA_C3181	1.73e-121	357.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,36E1E@31979|Clostridiaceae	186801|Clostridia	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N,RCC1_2
IOLKFBCL_00283	1195236.CTER_2894	1.64e-157	449.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	appB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
IOLKFBCL_00284	86416.Clopa_1034	2.76e-239	677.0	COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,25CDM@186801|Clostridia,36EUU@31979|Clostridiaceae	186801|Clostridia	E	family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
IOLKFBCL_00285	78345.BMERY_0419	1.34e-12	70.1	2A2J6@1|root,30QX2@2|Bacteria,2H59P@201174|Actinobacteria,4D29B@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00286	216816.GS08_00175	0.0	1068.0	COG1414@1|root,COG2865@1|root,COG1414@2|Bacteria,COG2865@2|Bacteria,2I3IG@201174|Actinobacteria,4CZRW@85004|Bifidobacteriales	201174|Actinobacteria	K	Putative ATP-dependent DNA helicase recG C-terminal	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4,MarR_2
IOLKFBCL_00287	326426.Bbr_0356	1.62e-294	803.0	COG1373@1|root,COG1373@2|Bacteria,2I96U@201174|Actinobacteria,4CZD7@85004|Bifidobacteriales	201174|Actinobacteria	S	AAA domain	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
IOLKFBCL_00288	326426.Bbr_0355	3.8e-226	624.0	COG0395@1|root,COG0395@2|Bacteria,2GJPZ@201174|Actinobacteria,4CZTQ@85004|Bifidobacteriales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
IOLKFBCL_00289	326426.Bbr_0354	7.54e-211	583.0	COG1175@1|root,COG1175@2|Bacteria,2GMTW@201174|Actinobacteria,4CZW4@85004|Bifidobacteriales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
IOLKFBCL_00290	326426.Bbr_0353	0.0	920.0	COG1653@1|root,COG1653@2|Bacteria,2GJIP@201174|Actinobacteria,4CZWR@85004|Bifidobacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
IOLKFBCL_00292	326426.Bbr_0352	0.0	1041.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria,4D246@85004|Bifidobacteriales	201174|Actinobacteria	P	Domain of unknown function (DUF4976)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
IOLKFBCL_00293	326426.Bbr_0351	2.75e-245	674.0	COG1609@1|root,COG1609@2|Bacteria,2GJ5Q@201174|Actinobacteria,4D041@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
IOLKFBCL_00294	326426.Bbr_0350	0.0	902.0	COG0641@1|root,COG0641@2|Bacteria,2HZTM@201174|Actinobacteria,4D1Q0@85004|Bifidobacteriales	201174|Actinobacteria	C	Iron-sulfur cluster-binding domain	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
IOLKFBCL_00295	326426.Bbr_0349	1.64e-171	481.0	COG0730@1|root,COG0730@2|Bacteria,2I5VT@201174|Actinobacteria,4D23D@85004|Bifidobacteriales	201174|Actinobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
IOLKFBCL_00297	1193128.A200_01736	8.9e-123	370.0	COG0641@1|root,COG0641@2|Bacteria	2|Bacteria	C	radical SAM	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
IOLKFBCL_00298	1437608.BBIA_0501	8.86e-107	316.0	COG1131@1|root,COG1131@2|Bacteria,2I8XU@201174|Actinobacteria,4D1YA@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter, ATP-binding protein	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
IOLKFBCL_00299	1437608.BBIA_0500	8.83e-106	315.0	COG0842@1|root,COG0842@2|Bacteria,2GX65@201174|Actinobacteria,4D1UZ@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
IOLKFBCL_00300	1437610.BREU_1625	3.37e-229	639.0	COG3464@1|root,COG3464@2|Bacteria,2IP45@201174|Actinobacteria,4D04T@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
IOLKFBCL_00301	649764.HMPREF0762_01348	2.54e-183	523.0	COG1373@1|root,COG1373@2|Bacteria,2GK4E@201174|Actinobacteria,4CVEF@84998|Coriobacteriia	84998|Coriobacteriia	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
IOLKFBCL_00302	216816.GS08_00160	2.65e-306	835.0	COG0477@1|root,COG2814@2|Bacteria,2I2ID@201174|Actinobacteria,4CZX9@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	ko:K08177	-	-	-	-	ko00000,ko02000	2.A.1.11	-	-	MFS_1
IOLKFBCL_00303	216816.GS08_00155	0.0	1158.0	COG0492@1|root,COG3634@1|root,COG0492@2|Bacteria,COG3634@2|Bacteria,2GKD2@201174|Actinobacteria,4CZ6G@85004|Bifidobacteriales	201174|Actinobacteria	C	Thioredoxin domain	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Thioredoxin_3
IOLKFBCL_00304	216816.GS08_00150	9.71e-138	389.0	COG0450@1|root,COG0450@2|Bacteria,2GM74@201174|Actinobacteria,4CZXS@85004|Bifidobacteriales	201174|Actinobacteria	O	C-terminal domain of 1-Cys peroxiredoxin	ahpC	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
IOLKFBCL_00305	216816.GS08_00145	1.28e-155	437.0	COG0288@1|root,COG0288@2|Bacteria,2GT5H@201174|Actinobacteria,4D06V@85004|Bifidobacteriales	201174|Actinobacteria	P	Reversible hydration of carbon dioxide	cah	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
IOLKFBCL_00306	762211.BSTEL_0971	5.94e-87	275.0	COG0842@1|root,COG1131@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,2GKEU@201174|Actinobacteria,4D1IQ@85004|Bifidobacteriales	201174|Actinobacteria	V	Forkhead associated domain	-	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0030312,GO:0031224,GO:0042623,GO:0042626,GO:0043492,GO:0044424,GO:0044425,GO:0044444,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	ko:K01990,ko:K21397	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC_tran,FHA,Yop-YscD_cpl
IOLKFBCL_00307	326426.Bbr_0036	5.24e-258	709.0	COG1672@1|root,COG1672@2|Bacteria,2GWBV@201174|Actinobacteria,4CZV8@85004|Bifidobacteriales	201174|Actinobacteria	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
IOLKFBCL_00308	326426.Bbr_0035	3.36e-305	834.0	COG1253@1|root,COG1253@2|Bacteria,2GKN5@201174|Actinobacteria,4CZKA@85004|Bifidobacteriales	201174|Actinobacteria	P	Transporter associated domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
IOLKFBCL_00309	326426.Bbr_0016	5.42e-110	316.0	COG0783@1|root,COG0783@2|Bacteria,2IFDP@201174|Actinobacteria,4CZV3@85004|Bifidobacteriales	201174|Actinobacteria	P	Belongs to the Dps family	dps	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
IOLKFBCL_00310	1437609.BCAL_0397	4.39e-191	533.0	COG1023@1|root,COG1023@2|Bacteria,2I2DH@201174|Actinobacteria,4CZR5@85004|Bifidobacteriales	201174|Actinobacteria	G	6-phosphogluconate dehydrogenase, C-terminal domain	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
IOLKFBCL_00311	1437608.BBIA_2395	8.79e-112	323.0	COG3265@1|root,COG3265@2|Bacteria,2GMW2@201174|Actinobacteria,4D0QX@85004|Bifidobacteriales	201174|Actinobacteria	F	Shikimate kinase	gntK	-	2.7.1.12,2.7.1.71	ko:K00851,ko:K00891	ko00030,ko00400,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00400,map01100,map01110,map01120,map01130,map01200,map01230	M00022	R01737,R02412	RC00002,RC00017,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
IOLKFBCL_00312	1437609.BCAL_0399	5.1e-294	808.0	COG2610@1|root,COG2610@2|Bacteria,2GITQ@201174|Actinobacteria,4CZR3@85004|Bifidobacteriales	201174|Actinobacteria	EG	GntP family permease	gnuT	-	-	ko:K03299	-	-	-	-	ko00000,ko02000	2.A.8	-	-	GntP_permease
IOLKFBCL_00313	1437608.BBIA_2393	5.44e-119	347.0	COG2186@1|root,COG2186@2|Bacteria,2GKBM@201174|Actinobacteria,4CYZS@85004|Bifidobacteriales	201174|Actinobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
IOLKFBCL_00314	216816.GS08_00110	1.24e-187	523.0	COG1451@1|root,COG1451@2|Bacteria,2GMP6@201174|Actinobacteria,4CZF9@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
IOLKFBCL_00315	762211.BSTEL_1913	6.13e-257	710.0	COG1373@1|root,COG1373@2|Bacteria,2ICQ6@201174|Actinobacteria,4D04Z@85004|Bifidobacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
IOLKFBCL_00316	443906.CMM_2194	5.22e-34	129.0	COG1011@1|root,COG1011@2|Bacteria,2I53Y@201174|Actinobacteria,4FTPD@85023|Microbacteriaceae	201174|Actinobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
IOLKFBCL_00317	1123065.ATWL01000002_gene1504	4.19e-24	106.0	COG1737@1|root,COG1737@2|Bacteria,2HY2W@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator, rpir family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
IOLKFBCL_00318	1158608.I583_02323	6.71e-144	414.0	COG3221@1|root,COG3221@2|Bacteria,1TR0H@1239|Firmicutes,4HBJQ@91061|Bacilli,4B0DG@81852|Enterococcaceae	91061|Bacilli	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
IOLKFBCL_00319	1158608.I583_02322	1.7e-104	310.0	COG3638@1|root,COG3638@2|Bacteria,1TQG6@1239|Firmicutes,4HC3N@91061|Bacilli,4B1GW@81852|Enterococcaceae	91061|Bacilli	P	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system	phnC	-	3.6.3.28	ko:K02041	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.9	-	-	ABC_tran
IOLKFBCL_00320	1158609.I586_02120	5.11e-101	302.0	COG3639@1|root,COG3639@2|Bacteria,1TR1S@1239|Firmicutes,4HBT8@91061|Bacilli,4B0SX@81852|Enterococcaceae	91061|Bacilli	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
IOLKFBCL_00321	1158608.I583_02320	8.22e-105	311.0	COG3639@1|root,COG3639@2|Bacteria,1TQ73@1239|Firmicutes,4HBI5@91061|Bacilli,4B6VX@81852|Enterococcaceae	91061|Bacilli	U	Binding-protein-dependent transport system inner membrane component	ptxC	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
IOLKFBCL_00322	1158608.I583_02319	2.19e-74	244.0	COG0737@1|root,COG0737@2|Bacteria,1TVGD@1239|Firmicutes,4I2HX@91061|Bacilli,4AZS9@81852|Enterococcaceae	91061|Bacilli	F	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
IOLKFBCL_00326	356829.BITS_1714	1.49e-48	165.0	292A9@1|root,2ZPUU@2|Bacteria,2GSI5@201174|Actinobacteria,4D2CQ@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00327	702459.BBPR_0068	1.35e-55	195.0	COG4584@1|root,COG4584@2|Bacteria,2IBDV@201174|Actinobacteria,4CZS6@85004|Bifidobacteriales	201174|Actinobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve
IOLKFBCL_00328	1050201.KB913034_gene1271	3.58e-38	129.0	COG3077@1|root,COG3077@2|Bacteria,1VABY@1239|Firmicutes,3VS2P@526524|Erysipelotrichia	526524|Erysipelotrichia	L	RelB antitoxin	-	-	-	-	-	-	-	-	-	-	-	-	RelB
IOLKFBCL_00330	158787.BSCA_0150	1.24e-86	266.0	COG1737@1|root,COG1737@2|Bacteria,2HY2W@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator, rpir family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
IOLKFBCL_00331	158787.BSCA_0149	3.12e-166	474.0	COG1840@1|root,COG1840@2|Bacteria,2I8D6@201174|Actinobacteria	201174|Actinobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_11,SBP_bac_6
IOLKFBCL_00332	158787.BSCA_0148	1.94e-245	691.0	COG1178@1|root,COG1178@2|Bacteria,2GKPT@201174|Actinobacteria	201174|Actinobacteria	P	Binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
IOLKFBCL_00333	158787.BSCA_0147	2.66e-126	375.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4CZPE@85004|Bifidobacteriales	201174|Actinobacteria	E	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
IOLKFBCL_00334	158787.BSCA_0146	2.28e-143	430.0	COG1409@1|root,COG2365@1|root,COG1409@2|Bacteria,COG2365@2|Bacteria	2|Bacteria	T	protein tyrosine phosphatase activity	cpdA	-	2.1.2.2,3.1.3.48,3.1.4.17,3.1.4.53	ko:K01104,ko:K01120,ko:K03651,ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,ko02025,map00230,map00670,map01100,map01110,map01130,map02025	M00048	R00191,R01234,R04325,R04326	RC00026,RC00197,RC00296,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Metallophos,Y_phosphatase3
IOLKFBCL_00335	326426.Bbr_0012	9.28e-317	864.0	COG0334@1|root,COG0334@2|Bacteria,2GKXG@201174|Actinobacteria,4CYTN@85004|Bifidobacteriales	201174|Actinobacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
IOLKFBCL_00336	216816.GS08_00040	0.0	940.0	COG1672@1|root,COG1672@2|Bacteria,2GMAZ@201174|Actinobacteria,4CZTD@85004|Bifidobacteriales	201174|Actinobacteria	S	ATPase domain predominantly from Archaea	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	ATPase_2,DUF234
IOLKFBCL_00337	216816.GS08_00035	1.08e-105	308.0	COG3266@1|root,COG3266@2|Bacteria,2GKZP@201174|Actinobacteria,4D0XB@85004|Bifidobacteriales	201174|Actinobacteria	S	Transmembrane domain of unknown function (DUF3566)	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF3566
IOLKFBCL_00338	216816.GS08_00030	0.0	1689.0	COG0188@1|root,COG0188@2|Bacteria,2GJ2Q@201174|Actinobacteria,4CYRP@85004|Bifidobacteriales	201174|Actinobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0008094,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034335,GO:0042623,GO:0061505,GO:0140097	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
IOLKFBCL_00339	216816.GS08_00025	0.0	1375.0	COG0187@1|root,COG0187@2|Bacteria,2GKGP@201174|Actinobacteria,4CZ47@85004|Bifidobacteriales	201174|Actinobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
IOLKFBCL_00340	216816.GS08_00020	2.31e-105	304.0	COG5512@1|root,COG5512@2|Bacteria,2GNQ4@201174|Actinobacteria,4D157@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
IOLKFBCL_00341	216816.GS08_00015	1.93e-284	778.0	COG1195@1|root,COG1195@2|Bacteria,2GJCS@201174|Actinobacteria,4CZQT@85004|Bifidobacteriales	201174|Actinobacteria	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
IOLKFBCL_00342	216816.GS08_00010	6.2e-264	723.0	COG0592@1|root,COG0592@2|Bacteria,2GJK3@201174|Actinobacteria,4CZTV@85004|Bifidobacteriales	201174|Actinobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
IOLKFBCL_00343	216816.GS08_00005	0.0	981.0	COG0593@1|root,COG0593@2|Bacteria,2GJKI@201174|Actinobacteria,4CZDW@85004|Bifidobacteriales	201174|Actinobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C
IOLKFBCL_00344	1122228.AQXR01000009_gene1328	3.25e-20	80.9	COG0230@1|root,COG0230@2|Bacteria,2GQFY@201174|Actinobacteria,4D1EF@85004|Bifidobacteriales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
IOLKFBCL_00345	216816.GS08_10585	5.81e-45	147.0	COG0594@1|root,COG0594@2|Bacteria,2HZPS@201174|Actinobacteria,4D16S@85004|Bifidobacteriales	201174|Actinobacteria	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
IOLKFBCL_00346	216816.GS08_10580	4.24e-224	619.0	COG0706@1|root,COG0706@2|Bacteria,2GJBU@201174|Actinobacteria,4CYZ2@85004|Bifidobacteriales	201174|Actinobacteria	U	Membrane protein insertase, YidC Oxa1 family	yidC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
IOLKFBCL_00347	216816.GS08_10575	2.13e-118	339.0	COG1847@1|root,COG1847@2|Bacteria,2GPZK@201174|Actinobacteria,4CYQQ@85004|Bifidobacteriales	201174|Actinobacteria	S	Putative single-stranded nucleic acids-binding domain	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	KH_4,R3H
IOLKFBCL_00348	216816.GS08_10570	2.41e-157	441.0	COG0357@1|root,COG0357@2|Bacteria,2GM9Z@201174|Actinobacteria,4CZ29@85004|Bifidobacteriales	201174|Actinobacteria	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
IOLKFBCL_00349	216816.GS08_10565	1.49e-227	627.0	COG1192@1|root,COG1192@2|Bacteria,2GMU7@201174|Actinobacteria,4CZ2D@85004|Bifidobacteriales	201174|Actinobacteria	D	CobQ CobB MinD ParA nucleotide binding domain protein	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
IOLKFBCL_00350	216816.GS08_10560	3.36e-292	801.0	COG1475@1|root,COG1475@2|Bacteria,2GNRN@201174|Actinobacteria,4CYUE@85004|Bifidobacteriales	201174|Actinobacteria	K	Belongs to the ParB family	parB	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005694,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0060187,GO:0071944	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
IOLKFBCL_00351	216816.GS08_10555	3.71e-236	650.0	COG0492@1|root,COG0492@2|Bacteria,2GKD2@201174|Actinobacteria,4CYU9@85004|Bifidobacteriales	201174|Actinobacteria	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
IOLKFBCL_00352	216816.GS08_10550	0.0	1220.0	COG0728@1|root,COG0728@2|Bacteria,2GKN0@201174|Actinobacteria,4CZ8M@85004|Bifidobacteriales	201174|Actinobacteria	KLT	MviN-like protein	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
IOLKFBCL_00353	326426.Bbr_1917	9.77e-269	777.0	COG0728@1|root,COG0728@2|Bacteria,2GKN0@201174|Actinobacteria,4CZ8M@85004|Bifidobacteriales	201174|Actinobacteria	KLT	MviN-like protein	mviN	GO:0003674,GO:0005215,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
IOLKFBCL_00354	216816.GS08_10540	0.0	1275.0	2CETP@1|root,33P5Y@2|Bacteria,2GMJ0@201174|Actinobacteria,4CZCV@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00355	216816.GS08_10535	1.66e-262	724.0	COG0494@1|root,COG0494@2|Bacteria,2GWEB@201174|Actinobacteria,4CZAV@85004|Bifidobacteriales	201174|Actinobacteria	L	Belongs to the Nudix hydrolase family	mutT4	-	-	-	-	-	-	-	-	-	-	-	NUDIX
IOLKFBCL_00356	216816.GS08_10530	0.0	940.0	COG0617@1|root,COG0617@2|Bacteria,2GMT1@201174|Actinobacteria,4CYUH@85004|Bifidobacteriales	201174|Actinobacteria	J	Probable RNA and SrmB- binding site of polymerase A	pcnA	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
IOLKFBCL_00357	216816.GS08_10525	3.83e-139	394.0	2E1BJ@1|root,32WRF@2|Bacteria,2IKG0@201174|Actinobacteria,4D0S1@85004|Bifidobacteriales	201174|Actinobacteria	S	LytR cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C
IOLKFBCL_00358	216816.GS08_10520	1.8e-220	608.0	COG1947@1|root,COG1947@2|Bacteria,2GKXD@201174|Actinobacteria,4CZMW@85004|Bifidobacteriales	201174|Actinobacteria	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0040007,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
IOLKFBCL_00359	216816.GS08_10515	2.74e-213	590.0	COG0030@1|root,COG0030@2|Bacteria,2GKBT@201174|Actinobacteria,4CYS9@85004|Bifidobacteriales	201174|Actinobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
IOLKFBCL_00360	216816.GS08_10510	2.61e-280	775.0	COG3583@1|root,COG3583@2|Bacteria,2H4RU@201174|Actinobacteria,4CYY0@85004|Bifidobacteriales	201174|Actinobacteria	S	G5	rpfB	GO:0005575,GO:0005576,GO:0008150,GO:0009892,GO:0009893,GO:0010468,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019222,GO:0022611,GO:0032502,GO:0040008,GO:0040009,GO:0040010,GO:0044111,GO:0044114,GO:0044115,GO:0044403,GO:0044419,GO:0045927,GO:0048518,GO:0048519,GO:0050789,GO:0051704,GO:0060255,GO:0065007,GO:0085016	-	ko:K21688	-	-	-	-	ko00000	-	-	-	DUF348,G5,Transglycosylas
IOLKFBCL_00362	216816.GS08_10500	6.2e-172	486.0	COG1651@1|root,COG1651@2|Bacteria,2GN3N@201174|Actinobacteria,4CZBD@85004|Bifidobacteriales	201174|Actinobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
IOLKFBCL_00363	216816.GS08_10495	0.0	947.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria,4CYQG@85004|Bifidobacteriales	201174|Actinobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
IOLKFBCL_00364	216816.GS08_10470	1.62e-57	178.0	COG0695@1|root,COG0695@2|Bacteria,2IRCP@201174|Actinobacteria,4D17U@85004|Bifidobacteriales	201174|Actinobacteria	O	Glutaredoxin	nrdH	-	-	ko:K06191	-	-	-	-	ko00000	-	-	-	Glutaredoxin
IOLKFBCL_00365	216816.GS08_10465	1.03e-106	307.0	COG1780@1|root,COG1780@2|Bacteria,2IM4D@201174|Actinobacteria,4D0XV@85004|Bifidobacteriales	201174|Actinobacteria	F	Probably involved in ribonucleotide reductase function	nrdI	-	-	ko:K03647	-	-	-	-	ko00000	-	-	-	Flavodoxin_NdrI
IOLKFBCL_00366	216816.GS08_10460	0.0	1405.0	COG0209@1|root,COG0209@2|Bacteria,2GKX9@201174|Actinobacteria,4CZF3@85004|Bifidobacteriales	201174|Actinobacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdE	GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005971,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016020,GO:0016491,GO:0016725,GO:0016728,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0051063,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0071944,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	RNR_N,Ribonuc_red_lgC,Ribonuc_red_lgN
IOLKFBCL_00368	216816.GS08_10450	7.28e-243	666.0	COG0208@1|root,COG0208@2|Bacteria,2GK46@201174|Actinobacteria,4CYQ2@85004|Bifidobacteriales	201174|Actinobacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0071704,GO:0090304,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990204	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
IOLKFBCL_00369	216816.GS08_10445	3.15e-277	758.0	COG0463@1|root,COG0463@2|Bacteria,2I2GT@201174|Actinobacteria,4CZ0W@85004|Bifidobacteriales	201174|Actinobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
IOLKFBCL_00370	216816.GS08_10440	1.47e-267	733.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4CYU6@85004|Bifidobacteriales	201174|Actinobacteria	E	Belongs to the ABC transporter superfamily	ugpC	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
IOLKFBCL_00371	216816.GS08_10435	0.0	925.0	COG0515@1|root,COG0515@2|Bacteria,2I2F0@201174|Actinobacteria,4CZ2E@85004|Bifidobacteriales	201174|Actinobacteria	KLT	Domain of unknown function (DUF4032)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4032,Kdo
IOLKFBCL_00372	216816.GS08_10430	2.64e-220	609.0	COG0566@1|root,COG0566@2|Bacteria,2GJMR@201174|Actinobacteria,4CZB1@85004|Bifidobacteriales	201174|Actinobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	rlmB	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
IOLKFBCL_00373	326426.Bbr_1881	1.27e-257	710.0	COG0477@1|root,COG2814@2|Bacteria,2GJU2@201174|Actinobacteria,4CZVY@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
IOLKFBCL_00374	216816.GS08_10420	0.0	881.0	COG1373@1|root,COG1373@2|Bacteria,2HJ52@201174|Actinobacteria,4D2TQ@85004|Bifidobacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
IOLKFBCL_00375	1246448.ANAZ01000035_gene168	4.7e-60	203.0	COG1609@1|root,COG1609@2|Bacteria,2GK1X@201174|Actinobacteria,4EHAQ@85012|Streptosporangiales	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
IOLKFBCL_00376	43759.JNWK01000061_gene2644	9.63e-73	242.0	COG1653@1|root,COG1653@2|Bacteria,2GJIP@201174|Actinobacteria	201174|Actinobacteria	G	Extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
IOLKFBCL_00377	266940.Krad_4189	1.39e-95	292.0	COG1175@1|root,COG1175@2|Bacteria,2GMTW@201174|Actinobacteria	201174|Actinobacteria	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
IOLKFBCL_00378	266940.Krad_4190	9.88e-92	282.0	COG0395@1|root,COG0395@2|Bacteria,2GJPZ@201174|Actinobacteria	201174|Actinobacteria	G	Binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
IOLKFBCL_00379	158787.BSCA_0159	4.62e-14	67.8	COG3293@1|root,COG3293@2|Bacteria,2GX1N@201174|Actinobacteria,4D2D5@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_2
IOLKFBCL_00380	158787.BSCA_0158	7.59e-61	190.0	COG3293@1|root,COG3293@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4096
IOLKFBCL_00381	1437610.BREU_0378	4.27e-121	362.0	2BVX8@1|root,30QZQ@2|Bacteria,2HZST@201174|Actinobacteria,4D1KZ@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00382	158787.BSCA_2285	3.02e-281	786.0	COG3934@1|root,COG3934@2|Bacteria,2I5AM@201174|Actinobacteria	201174|Actinobacteria	G	Domain of unknown function (DUF4091)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4091
IOLKFBCL_00383	326426.Bbr_1880	0.0	988.0	COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,2GKPM@201174|Actinobacteria,4D069@85004|Bifidobacteriales	201174|Actinobacteria	G	phosphotransferase system, EIIB	nagE	-	2.7.1.193	ko:K02802,ko:K02803,ko:K02804	ko00520,ko02060,map00520,map02060	M00267	R05199	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7	-	-	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
IOLKFBCL_00384	326426.Bbr_1879	2.15e-110	318.0	COG2190@1|root,COG2190@2|Bacteria,2INQB@201174|Actinobacteria,4D11R@85004|Bifidobacteriales	201174|Actinobacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1	-	-	2.7.1.208	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	M00265,M00266,M00268,M00270,M00272,M00303,M00806	R02738,R02780,R04111,R04394,R05132,R08559	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.1,4.A.1.1.11,4.A.1.1.12	-	-	PTS_EIIA_1
IOLKFBCL_00385	1437609.BCAL_1414	4.12e-21	91.3	COG1609@1|root,COG1609@2|Bacteria,2GJRG@201174|Actinobacteria,4CZ05@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
IOLKFBCL_00386	216816.GS08_10410	0.0	1801.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4CZ1I@85004|Bifidobacteriales	201174|Actinobacteria	P	Cation transporter/ATPase, N-terminus	pacL2	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
IOLKFBCL_00387	1437600.JDUI01000002_gene1568	8.83e-210	597.0	COG3469@1|root,COG3525@1|root,COG3469@2|Bacteria,COG3525@2|Bacteria,2ICVB@201174|Actinobacteria,4D04M@85004|Bifidobacteriales	201174|Actinobacteria	G	Glycosyl hydrolase, family 20, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18
IOLKFBCL_00388	702459.BBPR_1021	2.58e-220	623.0	COG1823@1|root,COG1823@2|Bacteria,2I862@201174|Actinobacteria,4D08P@85004|Bifidobacteriales	201174|Actinobacteria	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	ko:K06956	-	-	-	-	ko00000	-	-	-	SDF
IOLKFBCL_00389	216816.GS08_10405	4.31e-184	535.0	2DDMI@1|root,2ZIJN@2|Bacteria,2ICIR@201174|Actinobacteria,4D00F@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	FIVAR
IOLKFBCL_00390	216816.GS08_10400	4.97e-143	402.0	COG0717@1|root,COG0717@2|Bacteria,2GKQQ@201174|Actinobacteria,4CZEB@85004|Bifidobacteriales	201174|Actinobacteria	F	Belongs to the dCTP deaminase family	dcd	GO:0003674,GO:0003824,GO:0004170,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0019239,GO:0033973,GO:0047429	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	DCD
IOLKFBCL_00391	258533.BN977_00998	1.31e-93	288.0	COG0524@1|root,COG0524@2|Bacteria,2GKQP@201174|Actinobacteria,236N7@1762|Mycobacteriaceae	201174|Actinobacteria	G	pfkB family carbohydrate kinase	scrK	-	-	-	-	-	-	-	-	-	-	-	PfkB
IOLKFBCL_00392	246196.MSMEI_0490	6.76e-114	334.0	COG1349@1|root,COG1349@2|Bacteria,2GMAJ@201174|Actinobacteria,237GP@1762|Mycobacteriaceae	201174|Actinobacteria	K	DeoR C terminal sensor domain	-	-	-	ko:K02444	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
IOLKFBCL_00393	246196.MSMEI_0489	3.76e-233	652.0	COG1486@1|root,COG1486@2|Bacteria,2GK80@201174|Actinobacteria,2355E@1762|Mycobacteriaceae	201174|Actinobacteria	G	Family 4 glycosyl hydrolase	-	-	3.2.1.86	ko:K01222	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT4	-	Glyco_hydro_4,Glyco_hydro_4C
IOLKFBCL_00394	216816.GS08_10190	3.87e-162	472.0	COG1653@1|root,COG1653@2|Bacteria,2I3WZ@201174|Actinobacteria,4D0RG@85004|Bifidobacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
IOLKFBCL_00395	216816.GS08_10185	3.44e-138	398.0	COG1175@1|root,COG1175@2|Bacteria,2GNCE@201174|Actinobacteria,4D168@85004|Bifidobacteriales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
IOLKFBCL_00396	1341695.BBOMB_0780	6.09e-110	327.0	COG0395@1|root,COG0395@2|Bacteria,2HD58@201174|Actinobacteria,4D0TM@85004|Bifidobacteriales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
IOLKFBCL_00397	216816.GS08_10175	0.0	1207.0	COG0383@1|root,COG0383@2|Bacteria,2GM02@201174|Actinobacteria,4D222@85004|Bifidobacteriales	201174|Actinobacteria	G	Alpha mannosidase, middle domain	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
IOLKFBCL_00398	1437609.BCAL_0543	1.81e-153	435.0	COG0363@1|root,COG0363@2|Bacteria,2GK7F@201174|Actinobacteria,4CYYE@85004|Bifidobacteriales	201174|Actinobacteria	G	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
IOLKFBCL_00399	877414.ATWA01000001_gene952	2.85e-50	170.0	COG2364@1|root,COG2364@2|Bacteria,1V7I4@1239|Firmicutes,24IYE@186801|Clostridia	186801|Clostridia	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	YitT_membrane
IOLKFBCL_00400	216816.GS08_10395	1.34e-178	500.0	2BFMF@1|root,329FS@2|Bacteria,2IGC7@201174|Actinobacteria,4D0RD@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00401	216816.GS08_10390	2.07e-187	520.0	COG0400@1|root,COG0400@2|Bacteria,2I5NR@201174|Actinobacteria,4CZJQ@85004|Bifidobacteriales	201174|Actinobacteria	S	Phospholipase/Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
IOLKFBCL_00402	216816.GS08_10385	0.0	1263.0	COG0025@1|root,COG0025@2|Bacteria,2GIUT@201174|Actinobacteria,4CZC4@85004|Bifidobacteriales	201174|Actinobacteria	P	Sodium/hydrogen exchanger family	nhaP	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
IOLKFBCL_00403	216816.GS08_10380	3.4e-106	306.0	COG0590@1|root,COG0590@2|Bacteria,2IM3Z@201174|Actinobacteria,4D0V0@85004|Bifidobacteriales	201174|Actinobacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.1,3.5.4.33	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922,R10223	RC00074,RC00477,RC00514,RC00809	ko00000,ko00001,ko01000,ko03016	-	-	-	MafB19-deam,dCMP_cyt_deam_1
IOLKFBCL_00404	216816.GS08_10375	0.0	1542.0	COG3345@1|root,COG3345@2|Bacteria,2GJJ1@201174|Actinobacteria,4CZJB@85004|Bifidobacteriales	201174|Actinobacteria	G	Glycosyl hydrolase family 36 N-terminal domain	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
IOLKFBCL_00405	326426.Bbr_1868	3.08e-285	780.0	COG1846@1|root,COG1940@1|root,COG1846@2|Bacteria,COG1940@2|Bacteria,2GMBH@201174|Actinobacteria,4CZK4@85004|Bifidobacteriales	201174|Actinobacteria	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	ROK
IOLKFBCL_00406	326426.Bbr_1867	2.68e-311	848.0	COG1653@1|root,COG1653@2|Bacteria,2GN9T@201174|Actinobacteria,4CZ4V@85004|Bifidobacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
IOLKFBCL_00407	326426.Bbr_1866	2.7e-208	578.0	COG1175@1|root,COG1175@2|Bacteria,2GKJI@201174|Actinobacteria,4CZPG@85004|Bifidobacteriales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
IOLKFBCL_00408	326426.Bbr_1865	7.15e-197	546.0	COG0395@1|root,COG0395@2|Bacteria,2GNQW@201174|Actinobacteria,4D02Q@85004|Bifidobacteriales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
IOLKFBCL_00409	1437603.BMON_1839	4.38e-10	63.2	COG3464@1|root,COG3464@2|Bacteria,2IP45@201174|Actinobacteria,4D11E@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
IOLKFBCL_00410	216816.GS08_10310	0.0	1161.0	COG0366@1|root,COG0366@2|Bacteria,2GKS4@201174|Actinobacteria,4CZT7@85004|Bifidobacteriales	201174|Actinobacteria	G	Alpha amylase, catalytic domain protein	-	-	3.2.1.10	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R01718,R01791,R06199	RC00028,RC00059,RC00077,RC00451	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459,Malt_amylase_C
IOLKFBCL_00411	216816.GS08_10305	1.76e-296	810.0	COG1171@1|root,COG1171@2|Bacteria,2GJAG@201174|Actinobacteria,4CYW0@85004|Bifidobacteriales	201174|Actinobacteria	E	Pyridoxal-phosphate dependent enzyme	ilvA	GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0016020,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901605	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1559	PALP,Thr_dehydrat_C
IOLKFBCL_00412	216816.GS08_10300	2.72e-187	519.0	COG0846@1|root,COG0846@2|Bacteria,2GJI3@201174|Actinobacteria,4CYUW@85004|Bifidobacteriales	201174|Actinobacteria	K	Sir2 family	cobB2	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
IOLKFBCL_00413	216816.GS08_04285	8.53e-117	335.0	2E443@1|root,32Z0D@2|Bacteria,2II6X@201174|Actinobacteria,4D0ZD@85004|Bifidobacteriales	201174|Actinobacteria	S	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
IOLKFBCL_00414	216816.GS08_04290	7.62e-138	389.0	COG0560@1|root,COG0560@2|Bacteria,2GMVR@201174|Actinobacteria,4D0CF@85004|Bifidobacteriales	201174|Actinobacteria	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
IOLKFBCL_00415	216816.GS08_04295	2.54e-209	577.0	COG0406@1|root,COG0406@2|Bacteria,2GN7B@201174|Actinobacteria,4CZFM@85004|Bifidobacteriales	201174|Actinobacteria	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
IOLKFBCL_00416	216816.GS08_04300	2.31e-296	810.0	COG2233@1|root,COG2233@2|Bacteria,2GMH6@201174|Actinobacteria,4CZR8@85004|Bifidobacteriales	201174|Actinobacteria	F	Permease family	rutG	-	-	ko:K02824,ko:K03458	-	-	-	-	ko00000,ko02000	2.A.40,2.A.40.1.1,2.A.40.1.2	-	-	Xan_ur_permease
IOLKFBCL_00418	216816.GS08_04305	0.0	1293.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,4CZ4K@85004|Bifidobacteriales	201174|Actinobacteria	JKL	helicase superfamily c-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
IOLKFBCL_00419	216816.GS08_04310	5.27e-37	130.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4D0BX@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
IOLKFBCL_00420	216816.GS08_04310	3.36e-42	144.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4D0BX@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
IOLKFBCL_00421	216816.GS08_04315	0.0	895.0	COG0366@1|root,COG0366@2|Bacteria,2GJUT@201174|Actinobacteria,4D075@85004|Bifidobacteriales	201174|Actinobacteria	G	Alpha amylase, catalytic domain	nplT	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459
IOLKFBCL_00422	216816.GS08_04320	3.63e-69	218.0	COG0306@1|root,COG0306@2|Bacteria,2GJHK@201174|Actinobacteria,4CZM7@85004|Bifidobacteriales	201174|Actinobacteria	P	Phosphate transporter family	pitB	GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	iNJ661.Rv2281	PHO4
IOLKFBCL_00423	216816.GS08_04325	5.51e-147	414.0	COG1392@1|root,COG1392@2|Bacteria,2HNQ5@201174|Actinobacteria,4CZVQ@85004|Bifidobacteriales	201174|Actinobacteria	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
IOLKFBCL_00424	216816.GS08_04330	8.95e-142	401.0	COG2197@1|root,COG2197@2|Bacteria,2IBZ9@201174|Actinobacteria,4D07J@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
IOLKFBCL_00425	216816.GS08_04335	9.07e-283	777.0	COG4585@1|root,COG4585@2|Bacteria,2I9G4@201174|Actinobacteria,4CZHY@85004|Bifidobacteriales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
IOLKFBCL_00426	158787.BSCA_2234	2.12e-14	71.6	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4D20B@85004|Bifidobacteriales	201174|Actinobacteria	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
IOLKFBCL_00427	326426.Bbr_0870	2.07e-236	650.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4CYUQ@85004|Bifidobacteriales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
IOLKFBCL_00428	216816.GS08_04350	2.74e-284	778.0	COG0842@1|root,COG0842@2|Bacteria,2IBJP@201174|Actinobacteria,4CZD5@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
IOLKFBCL_00429	216816.GS08_04355	4.33e-315	861.0	COG0842@1|root,COG0842@2|Bacteria,2H9HW@201174|Actinobacteria,4CZ1J@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
IOLKFBCL_00430	398513.BBNG_00718	0.0	980.0	COG2865@1|root,COG2865@2|Bacteria,2GZ30@201174|Actinobacteria,4CYSX@85004|Bifidobacteriales	201174|Actinobacteria	K	Putative ATP-dependent DNA helicase recG C-terminal	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4,HTH_24,HTH_5
IOLKFBCL_00431	216816.GS08_04365	1.65e-133	379.0	COG1569@1|root,COG1569@2|Bacteria,2IMP1@201174|Actinobacteria,4D13G@85004|Bifidobacteriales	201174|Actinobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
IOLKFBCL_00432	216816.GS08_04370	2.69e-116	333.0	COG3311@1|root,COG3311@2|Bacteria,2IQFY@201174|Actinobacteria,4D15C@85004|Bifidobacteriales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
IOLKFBCL_00434	158787.BSCA_1372	4.71e-31	117.0	COG2755@1|root,COG2755@2|Bacteria,2IPPH@201174|Actinobacteria,4D0X0@85004|Bifidobacteriales	201174|Actinobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
IOLKFBCL_00435	158787.BSCA_1372	1.08e-29	111.0	COG2755@1|root,COG2755@2|Bacteria,2IPPH@201174|Actinobacteria,4D0X0@85004|Bifidobacteriales	201174|Actinobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
IOLKFBCL_00436	158787.BSCA_0879	2.47e-134	388.0	2BE5B@1|root,327W0@2|Bacteria,2GP1A@201174|Actinobacteria,4CZYK@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00437	326426.Bbr_0875	1.67e-259	715.0	2CGVZ@1|root,33209@2|Bacteria,2IEU5@201174|Actinobacteria,4CZAJ@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00438	216816.GS08_04390	2.51e-143	404.0	COG3340@1|root,COG3340@2|Bacteria,2GN35@201174|Actinobacteria,4D10R@85004|Bifidobacteriales	201174|Actinobacteria	E	Peptidase family S51	pepE	GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564	3.4.13.21	ko:K05995	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
IOLKFBCL_00439	216816.GS08_04395	8.75e-138	390.0	COG1335@1|root,COG1335@2|Bacteria,2IFQW@201174|Actinobacteria,4CYTT@85004|Bifidobacteriales	201174|Actinobacteria	Q	Isochorismatase family	pncA	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006769,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0071704,GO:0072524,GO:1901360,GO:1901564	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
IOLKFBCL_00440	216816.GS08_04400	1.37e-95	278.0	COG0346@1|root,COG0346@2|Bacteria,2II51@201174|Actinobacteria,4D0XJ@85004|Bifidobacteriales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	gloA	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
IOLKFBCL_00441	216816.GS08_04405	2.06e-208	578.0	COG0791@1|root,COG0791@2|Bacteria,2I38D@201174|Actinobacteria,4D2XJ@85004|Bifidobacteriales	201174|Actinobacteria	M	pfam nlp p60	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00442	216816.GS08_04410	1.25e-203	562.0	COG2267@1|root,COG2267@2|Bacteria,2GNRY@201174|Actinobacteria,4D02B@85004|Bifidobacteriales	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
IOLKFBCL_00443	326426.Bbr_0880	4.22e-50	159.0	2B2KB@1|root,31V5N@2|Bacteria,2GV1B@201174|Actinobacteria,4D1EE@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF2975)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2975
IOLKFBCL_00444	216816.GS08_04420	5.21e-41	135.0	COG3655@1|root,COG3655@2|Bacteria,2GQZM@201174|Actinobacteria,4D1EQ@85004|Bifidobacteriales	201174|Actinobacteria	K	Cro/C1-type HTH DNA-binding domain	-	-	-	ko:K07727	-	-	-	-	ko00000,ko03000	-	-	-	HTH_26
IOLKFBCL_00445	326426.Bbr_0882	4.08e-305	834.0	COG2233@1|root,COG2233@2|Bacteria,2GMH6@201174|Actinobacteria,4CZ9F@85004|Bifidobacteriales	201174|Actinobacteria	F	Permease family	pbuX	-	-	ko:K03458	-	-	-	-	ko00000	2.A.40	-	-	Xan_ur_permease
IOLKFBCL_00446	216816.GS08_04430	6.02e-135	382.0	COG0503@1|root,COG0503@2|Bacteria,2GJ3S@201174|Actinobacteria,4CYSZ@85004|Bifidobacteriales	201174|Actinobacteria	F	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis	xpt	-	2.4.2.22	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01229,R02142	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
IOLKFBCL_00447	216816.GS08_04435	0.0	1556.0	COG0210@1|root,COG0210@2|Bacteria,2GISS@201174|Actinobacteria,4CYRJ@85004|Bifidobacteriales	201174|Actinobacteria	L	DNA helicase	pcrA	GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
IOLKFBCL_00448	216816.GS08_04440	2.11e-85	252.0	2CBVU@1|root,3324G@2|Bacteria,2IKKE@201174|Actinobacteria,4D106@85004|Bifidobacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4418)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4418
IOLKFBCL_00449	216816.GS08_04445	3.5e-272	747.0	COG0577@1|root,COG0577@2|Bacteria,2H8C2@201174|Actinobacteria,4CZB5@85004|Bifidobacteriales	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
IOLKFBCL_00450	216816.GS08_04450	9.92e-193	540.0	COG1136@1|root,COG1136@2|Bacteria,2IATV@201174|Actinobacteria,4CZMH@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IOLKFBCL_00451	216816.GS08_04455	1.29e-141	400.0	COG0522@1|root,COG0522@2|Bacteria,2GIRX@201174|Actinobacteria,4CYSP@85004|Bifidobacteriales	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
IOLKFBCL_00452	326426.Bbr_0889	1.92e-196	543.0	COG2071@1|root,COG2071@2|Bacteria,2GIV6@201174|Actinobacteria,4D043@85004|Bifidobacteriales	201174|Actinobacteria	S	Peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
IOLKFBCL_00453	216816.GS08_04465	1.43e-115	330.0	COG0295@1|root,COG0295@2|Bacteria,2IMXP@201174|Actinobacteria,4D1XM@85004|Bifidobacteriales	201174|Actinobacteria	F	cytidine deaminase activity	-	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
IOLKFBCL_00454	326426.Bbr_0891	7.72e-70	211.0	COG5658@1|root,COG5658@2|Bacteria,2GWJG@201174|Actinobacteria,4D1RC@85004|Bifidobacteriales	201174|Actinobacteria	S	SdpI/YhfL protein family	-	-	-	-	-	-	-	-	-	-	-	-	SdpI
IOLKFBCL_00455	216816.GS08_04475	5.99e-143	403.0	COG1305@1|root,COG1305@2|Bacteria,2GM42@201174|Actinobacteria,4D0N1@85004|Bifidobacteriales	201174|Actinobacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
IOLKFBCL_00456	216816.GS08_04480	6.1e-85	249.0	COG2337@1|root,COG2337@2|Bacteria,2GZTW@201174|Actinobacteria,4D25G@85004|Bifidobacteriales	201174|Actinobacteria	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PemK_toxin
IOLKFBCL_00457	326426.Bbr_0894	2.55e-65	198.0	COG3077@1|root,COG3077@2|Bacteria,2GRAY@201174|Actinobacteria,4D1J9@85004|Bifidobacteriales	201174|Actinobacteria	L	RelB antitoxin	-	-	-	ko:K07473	-	-	-	-	ko00000,ko02048	-	-	-	RelB
IOLKFBCL_00458	326426.Bbr_0895	2.43e-166	464.0	COG0406@1|root,COG0406@2|Bacteria,2GK2I@201174|Actinobacteria,4CZH2@85004|Bifidobacteriales	201174|Actinobacteria	G	Phosphoglycerate mutase family	-	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
IOLKFBCL_00459	216816.GS08_04500	8.24e-83	245.0	COG4768@1|root,COG4768@2|Bacteria,2II1J@201174|Actinobacteria,4D0VH@85004|Bifidobacteriales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF948)	-	-	-	-	-	-	-	-	-	-	-	-	DUF948
IOLKFBCL_00460	216816.GS08_04505	2.29e-48	154.0	2B9VR@1|root,3238X@2|Bacteria,2IQYT@201174|Actinobacteria,4D16I@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00461	216816.GS08_04510	0.0	1745.0	COG0013@1|root,COG0013@2|Bacteria,2GIUG@201174|Actinobacteria,4CZQN@85004|Bifidobacteriales	201174|Actinobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
IOLKFBCL_00462	216816.GS08_04515	6.41e-103	298.0	COG0816@1|root,COG0816@2|Bacteria,2IQB0@201174|Actinobacteria,4D0WQ@85004|Bifidobacteriales	201174|Actinobacteria	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	ruvX	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
IOLKFBCL_00463	216816.GS08_04520	7.79e-263	722.0	COG1559@1|root,COG1559@2|Bacteria,2GKGQ@201174|Actinobacteria,4CZID@85004|Bifidobacteriales	201174|Actinobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
IOLKFBCL_00464	216816.GS08_04525	2.5e-100	291.0	2B59B@1|root,31Y3G@2|Bacteria,2GRM1@201174|Actinobacteria,4D110@85004|Bifidobacteriales	201174|Actinobacteria	S	Type IV leader peptidase family	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	Peptidase_A24
IOLKFBCL_00465	216816.GS08_04530	7.77e-280	765.0	COG0082@1|root,COG0082@2|Bacteria,2GJJN@201174|Actinobacteria,4CZ43@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2540c	Chorismate_synt
IOLKFBCL_00466	216816.GS08_04535	0.0	1066.0	COG0337@1|root,COG0703@1|root,COG0337@2|Bacteria,COG0703@2|Bacteria,2GIUZ@201174|Actinobacteria,4CZ2G@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	GO:0003674,GO:0003824,GO:0003856,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
IOLKFBCL_00467	216816.GS08_04540	2.09e-104	301.0	COG0757@1|root,COG0757@2|Bacteria,2IMBY@201174|Actinobacteria,4D0Q6@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	GO:0003674,GO:0003824,GO:0003855,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:1901576	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
IOLKFBCL_00468	216816.GS08_04545	0.0	1111.0	COG0504@1|root,COG0504@2|Bacteria,2GJ13@201174|Actinobacteria,4CYWE@85004|Bifidobacteriales	201174|Actinobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1699	CTP_synth_N,GATase
IOLKFBCL_00469	216816.GS08_04550	0.0	1005.0	COG0719@1|root,COG0719@2|Bacteria,2GKCZ@201174|Actinobacteria,4CZPQ@85004|Bifidobacteriales	201174|Actinobacteria	O	FeS assembly protein SufB	sufB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
IOLKFBCL_00470	216816.GS08_04555	5.91e-299	815.0	COG0719@1|root,COG0719@2|Bacteria,2GJNV@201174|Actinobacteria,4CZEE@85004|Bifidobacteriales	201174|Actinobacteria	O	FeS assembly protein SufD	sufD	GO:0008150,GO:0009605,GO:0009607,GO:0040007,GO:0043207,GO:0044403,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
IOLKFBCL_00471	216816.GS08_04560	3.98e-184	512.0	COG0396@1|root,COG0396@2|Bacteria,2GKB7@201174|Actinobacteria,4CZU1@85004|Bifidobacteriales	201174|Actinobacteria	O	FeS assembly ATPase SufC	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
IOLKFBCL_00472	216816.GS08_04565	6.21e-303	826.0	COG0520@1|root,COG0520@2|Bacteria,2GIVK@201174|Actinobacteria,4CZIU@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
IOLKFBCL_00473	216816.GS08_04570	1.18e-132	375.0	COG0822@1|root,COG0822@2|Bacteria,2IHY9@201174|Actinobacteria,4CZU5@85004|Bifidobacteriales	201174|Actinobacteria	C	SUF system FeS assembly protein, NifU family	iscU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
IOLKFBCL_00474	216816.GS08_04575	1e-144	407.0	COG2151@1|root,COG2151@2|Bacteria,2IKUH@201174|Actinobacteria,4CYRH@85004|Bifidobacteriales	201174|Actinobacteria	S	Iron-sulfur cluster assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
IOLKFBCL_00475	216816.GS08_04580	1.79e-306	834.0	COG0448@1|root,COG0448@2|Bacteria,2I2EF@201174|Actinobacteria,4CZ4E@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
IOLKFBCL_00476	216816.GS08_04585	3.08e-209	578.0	COG0566@1|root,COG0566@2|Bacteria,2GJ12@201174|Actinobacteria,4CYQ6@85004|Bifidobacteriales	201174|Actinobacteria	J	SpoU rRNA Methylase family	spoU2	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
IOLKFBCL_00478	216816.GS08_04595	1.28e-183	511.0	COG1385@1|root,COG1385@2|Bacteria,2GTKX@201174|Actinobacteria,4CZAD@85004|Bifidobacteriales	201174|Actinobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
IOLKFBCL_00479	216816.GS08_04600	9.63e-77	228.0	COG0537@1|root,COG0537@2|Bacteria,2IHPT@201174|Actinobacteria,4D130@85004|Bifidobacteriales	201174|Actinobacteria	FG	Scavenger mRNA decapping enzyme C-term binding	hit	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	DcpS_C,HIT
IOLKFBCL_00480	216816.GS08_04605	2.38e-272	746.0	COG1702@1|root,COG1702@2|Bacteria,2GK0W@201174|Actinobacteria,4CZJH@85004|Bifidobacteriales	201174|Actinobacteria	T	PhoH-like protein	phoH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
IOLKFBCL_00481	216816.GS08_04610	1.44e-132	375.0	COG0319@1|root,COG0319@2|Bacteria,2GMUF@201174|Actinobacteria,4CZJF@85004|Bifidobacteriales	201174|Actinobacteria	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
IOLKFBCL_00482	216816.GS08_04615	0.0	874.0	COG1253@1|root,COG1253@2|Bacteria,2GIWR@201174|Actinobacteria,4CZ1W@85004|Bifidobacteriales	201174|Actinobacteria	S	CBS domain	corC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
IOLKFBCL_00483	216816.GS08_04620	1.61e-233	645.0	COG1159@1|root,COG1159@2|Bacteria,2GJJE@201174|Actinobacteria,4CYZH@85004|Bifidobacteriales	201174|Actinobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
IOLKFBCL_00484	216816.GS08_04625	0.0	1329.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4CYYJ@85004|Bifidobacteriales	201174|Actinobacteria	I	AMP-binding enzyme	fadD2	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
IOLKFBCL_00485	216816.GS08_04630	5.23e-258	709.0	COG3288@1|root,COG3288@2|Bacteria,2I2FZ@201174|Actinobacteria,4CZZ3@85004|Bifidobacteriales	201174|Actinobacteria	C	NAD(P) transhydrogenase subunit alpha part 1 K00324	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM
IOLKFBCL_00486	216816.GS08_04635	5.05e-58	180.0	COG3288@1|root,COG3288@2|Bacteria,2IKR9@201174|Actinobacteria,4D12D@85004|Bifidobacteriales	201174|Actinobacteria	C	4TM region of pyridine nucleotide transhydrogenase, mitoch	pntAB	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
IOLKFBCL_00487	216816.GS08_04640	1.43e-308	845.0	COG1282@1|root,COG1282@2|Bacteria,2GNKB@201174|Actinobacteria,4CZF5@85004|Bifidobacteriales	201174|Actinobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
IOLKFBCL_00488	216816.GS08_04645	1.08e-247	680.0	COG1073@1|root,COG1073@2|Bacteria,2HZEB@201174|Actinobacteria,4D02D@85004|Bifidobacteriales	201174|Actinobacteria	S	alpha beta	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_6,Hydrolase_4
IOLKFBCL_00489	216816.GS08_04650	1.54e-112	327.0	COG1825@1|root,COG1825@2|Bacteria,2GJPJ@201174|Actinobacteria,4CZ7W@85004|Bifidobacteriales	201174|Actinobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
IOLKFBCL_00490	326426.Bbr_0927	2.61e-286	780.0	COG0115@1|root,COG0115@2|Bacteria,2GKJ1@201174|Actinobacteria,4CZD9@85004|Bifidobacteriales	201174|Actinobacteria	E	Amino-transferase class IV	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
IOLKFBCL_00492	158787.BSCA_1069	2.02e-32	115.0	2EK5K@1|root,33DW0@2|Bacteria,2GSM4@201174|Actinobacteria,4D1J2@85004|Bifidobacteriales	201174|Actinobacteria	S	Putative phage holin Dp-1	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_Dp1
IOLKFBCL_00493	78345.BMERY_0862	1.43e-74	245.0	COG3757@1|root,COG3757@2|Bacteria,2I2GA@201174|Actinobacteria,4D07F@85004|Bifidobacteriales	201174|Actinobacteria	M	Glycosyl hydrolases family 25	-	-	-	-	-	-	-	-	-	-	-	-	CW_7,Glyco_hydro_25,LysM
IOLKFBCL_00494	158787.BSCA_0721	1.1e-26	102.0	2BJPU@1|root,32E1F@2|Bacteria,2GZ2E@201174|Actinobacteria,4D1PK@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00500	78346.BRUM_0385	4.39e-205	657.0	COG4372@1|root,COG4733@1|root,COG4372@2|Bacteria,COG4733@2|Bacteria,2ICJE@201174|Actinobacteria,4D2VJ@85004|Bifidobacteriales	201174|Actinobacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00502	35760.BCHO_0831	1.16e-180	600.0	COG0840@1|root,COG1196@1|root,COG1511@1|root,COG5412@1|root,COG0840@2|Bacteria,COG1196@2|Bacteria,COG1511@2|Bacteria,COG5412@2|Bacteria,2HZEA@201174|Actinobacteria,4D021@85004|Bifidobacteriales	201174|Actinobacteria	DNT	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00505	1692.BMAGN_1451	1.49e-90	271.0	2BII3@1|root,32CQU@2|Bacteria,2GSSI@201174|Actinobacteria,4D1IC@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00508	1692.BMAGN_1448	1.93e-84	253.0	29R0Q@1|root,30C1U@2|Bacteria,2GVV4@201174|Actinobacteria,4D1KY@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00509	1692.BMAGN_1447	2.76e-52	169.0	2B1US@1|root,31UAS@2|Bacteria,2GTRB@201174|Actinobacteria,4D1FX@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00510	1692.BMAGN_1446	1.54e-150	435.0	2B56X@1|root,31Y0T@2|Bacteria,2HZKE@201174|Actinobacteria,4D0T6@85004|Bifidobacteriales	201174|Actinobacteria	S	Phage major capsid protein E	-	-	-	-	-	-	-	-	-	-	-	-	Phage_cap_E
IOLKFBCL_00511	1692.BMAGN_1445	4.44e-69	217.0	2AVHC@1|root,31M9S@2|Bacteria,2IMWD@201174|Actinobacteria,4D13V@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00512	35760.BCHO_0841	1.04e-07	58.2	2BEGD@1|root,3287Q@2|Bacteria,2HDZS@201174|Actinobacteria,4D2K5@85004|Bifidobacteriales	35760.BCHO_0841|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00513	1692.BMAGN_1443	4.69e-114	342.0	2AYWB@1|root,307JP@2|Bacteria,2IIGR@201174|Actinobacteria,4D0ZW@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00514	1692.BMAGN_1442	1.34e-265	742.0	29W7F@1|root,30HSN@2|Bacteria,2IQFQ@201174|Actinobacteria,4CZHR@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phage_prot_Gp6
IOLKFBCL_00515	1692.BMAGN_1441	0.0	1083.0	COG4626@1|root,COG4626@2|Bacteria,2GNSB@201174|Actinobacteria,4D0MR@85004|Bifidobacteriales	201174|Actinobacteria	S	Terminase	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_1
IOLKFBCL_00524	326426.Bbr_0964	1.32e-168	471.0	COG0819@1|root,COG0819@2|Bacteria,2IA0S@201174|Actinobacteria,4CZUI@85004|Bifidobacteriales	201174|Actinobacteria	K	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway	tenA	-	3.5.99.2	ko:K03707	ko00730,ko01100,map00730,map01100	-	R02133,R09993	RC00224,RC00652,RC02832	ko00000,ko00001,ko01000,ko03000	-	-	-	TENA_THI-4
IOLKFBCL_00525	326426.Bbr_0963	1.5e-102	301.0	COG4186@1|root,COG4186@2|Bacteria,2IRS9@201174|Actinobacteria,4D018@85004|Bifidobacteriales	201174|Actinobacteria	S	phosphoesterase or phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
IOLKFBCL_00526	1437608.BBIA_0952	1.18e-27	107.0	COG4989@1|root,COG4989@2|Bacteria,2GM3C@201174|Actinobacteria,4CZZ2@85004|Bifidobacteriales	201174|Actinobacteria	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
IOLKFBCL_00527	1437608.BBIA_0952	2.77e-15	75.9	COG4989@1|root,COG4989@2|Bacteria,2GM3C@201174|Actinobacteria,4CZZ2@85004|Bifidobacteriales	201174|Actinobacteria	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
IOLKFBCL_00528	326426.Bbr_0961	3.08e-214	592.0	COG0657@1|root,COG0657@2|Bacteria,2GNKU@201174|Actinobacteria,4CZVA@85004|Bifidobacteriales	201174|Actinobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
IOLKFBCL_00529	762211.BSTEL_1237	6.45e-215	620.0	COG4715@1|root,COG4715@2|Bacteria	2|Bacteria	S	zinc ion binding	CP_1020	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N,SNF2_assoc,SWIM
IOLKFBCL_00530	326426.Bbr_0958	1.31e-163	456.0	COG3012@1|root,COG3012@2|Bacteria,2I5YJ@201174|Actinobacteria,4D17C@85004|Bifidobacteriales	201174|Actinobacteria	S	Plasmid pRiA4b ORF-3-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
IOLKFBCL_00531	158787.BSCA_1450	1.4e-43	152.0	COG2962@1|root,COG2962@2|Bacteria,2GKCP@201174|Actinobacteria,4D0PS@85004|Bifidobacteriales	201174|Actinobacteria	S	EamA-like transporter family	rarD	-	-	ko:K05786	-	-	-	-	ko00000,ko02000	2.A.7.7	-	-	EamA
IOLKFBCL_00534	216816.GS08_04890	1.75e-21	100.0	COG0346@1|root,COG4279@1|root,COG0346@2|Bacteria,COG4279@2|Bacteria,2HZT1@201174|Actinobacteria,4D1NI@85004|Bifidobacteriales	201174|Actinobacteria	E	Rard protein	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00535	1435051.BMOU_0078	1.17e-253	725.0	COG3410@1|root,COG3410@2|Bacteria,2HNSJ@201174|Actinobacteria,4CZG3@85004|Bifidobacteriales	201174|Actinobacteria	L	Uncharacterized conserved protein (DUF2075)	-	-	-	ko:K09384	-	-	-	-	ko00000	-	-	-	DUF2075
IOLKFBCL_00536	1341695.BBOMB_1314	9.97e-42	141.0	COG1694@1|root,COG1694@2|Bacteria,2IKRC@201174|Actinobacteria,4D155@85004|Bifidobacteriales	201174|Actinobacteria	S	MazG-like family	-	-	-	-	-	-	-	-	-	-	-	-	MazG-like
IOLKFBCL_00537	1437608.BBIA_0524	1.43e-09	59.3	COG0300@1|root,COG0300@2|Bacteria,2IIVW@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
IOLKFBCL_00538	158787.BSCA_1447	3.63e-76	242.0	COG4279@1|root,COG4715@1|root,COG4279@2|Bacteria,COG4715@2|Bacteria	2|Bacteria	S	zinc ion binding	CP_1020	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N,SWIM
IOLKFBCL_00539	326426.Bbr_0948	9.56e-179	499.0	2ARR4@1|root,31H25@2|Bacteria,2IG5G@201174|Actinobacteria,4D0U6@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00540	326426.Bbr_0947	7.59e-122	348.0	COG1225@1|root,COG1225@2|Bacteria,2IHZ6@201174|Actinobacteria,4D0PN@85004|Bifidobacteriales	201174|Actinobacteria	O	Redoxin	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
IOLKFBCL_00542	216816.GS08_04780	2.96e-206	570.0	COG0561@1|root,COG0561@2|Bacteria,2GNWG@201174|Actinobacteria,4CZY9@85004|Bifidobacteriales	201174|Actinobacteria	S	Sucrose-6F-phosphate phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
IOLKFBCL_00543	216816.GS08_04775	3.44e-201	557.0	COG1119@1|root,COG1119@2|Bacteria,2GIXX@201174|Actinobacteria,4CZDS@85004|Bifidobacteriales	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	ylmA	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
IOLKFBCL_00544	216816.GS08_04770	6.25e-308	838.0	COG0297@1|root,COG0297@2|Bacteria,2I2EE@201174|Actinobacteria,4CZKY@85004|Bifidobacteriales	201174|Actinobacteria	G	Starch synthase catalytic domain	glgA	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901576	2.4.1.342	ko:K16148	ko00500,ko01100,map00500,map01100	-	R02421,R11530	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
IOLKFBCL_00545	216816.GS08_04765	1.98e-105	304.0	2BI32@1|root,32C84@2|Bacteria,2IDD6@201174|Actinobacteria,4D0PC@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PsbJ
IOLKFBCL_00546	216816.GS08_04760	0.0	1341.0	28J61@1|root,2Z91S@2|Bacteria,2HZIR@201174|Actinobacteria,4D0KC@85004|Bifidobacteriales	201174|Actinobacteria	S	Glycosyl hydrolases related to GH101 family, GH129	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_129
IOLKFBCL_00547	216816.GS08_04755	0.0	1078.0	COG4166@1|root,COG4166@2|Bacteria,2GIUH@201174|Actinobacteria,4CZFK@85004|Bifidobacteriales	201174|Actinobacteria	E	ABC transporter, substrate-binding protein, family 5	dppA	-	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
IOLKFBCL_00548	216816.GS08_04750	0.0	1040.0	COG0493@1|root,COG0493@2|Bacteria,2GJ0A@201174|Actinobacteria,4CZ7B@85004|Bifidobacteriales	201174|Actinobacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	gltD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3858c	Fer4_20,Pyr_redox_2
IOLKFBCL_00549	216816.GS08_04745	0.0	3020.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,2GN09@201174|Actinobacteria,4CZB8@85004|Bifidobacteriales	201174|Actinobacteria	E	glutamate synthase NADPH large subunit	gltB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
IOLKFBCL_00550	216816.GS08_04715	7.3e-227	627.0	COG1609@1|root,COG1609@2|Bacteria,2GK1X@201174|Actinobacteria,4CZS8@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
IOLKFBCL_00553	1437609.BCAL_1160	2.78e-176	502.0	COG1929@1|root,COG1929@2|Bacteria,2GKHX@201174|Actinobacteria,4CZRH@85004|Bifidobacteriales	201174|Actinobacteria	G	Belongs to the glycerate kinase type-1 family	glxK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
IOLKFBCL_00554	326426.Bbr_0932	1.17e-226	632.0	COG0635@1|root,COG0635@2|Bacteria,2GJXX@201174|Actinobacteria,4CZ81@85004|Bifidobacteriales	201174|Actinobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	iNJ661.Rv2388c	HemN_C,Radical_SAM
IOLKFBCL_00555	216816.GS08_04675	0.0	1238.0	COG0481@1|root,COG0481@2|Bacteria,2GJAB@201174|Actinobacteria,4CYWI@85004|Bifidobacteriales	201174|Actinobacteria	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
IOLKFBCL_00556	216816.GS08_04670	6.75e-47	151.0	COG0268@1|root,COG0268@2|Bacteria,2IQ73@201174|Actinobacteria,4D18U@85004|Bifidobacteriales	201174|Actinobacteria	J	Binds directly to 16S ribosomal RNA	rpsT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
IOLKFBCL_00557	326426.Bbr_0929	1.98e-162	457.0	COG2860@1|root,COG2860@2|Bacteria,2GMI4@201174|Actinobacteria,4CZ51@85004|Bifidobacteriales	201174|Actinobacteria	S	UPF0126 domain	-	-	-	-	-	-	-	-	-	-	-	-	UPF0126
IOLKFBCL_00558	326426.Bbr_0928	2.55e-148	424.0	COG1694@1|root,COG3956@2|Bacteria,2GNKC@201174|Actinobacteria,4CZ9U@85004|Bifidobacteriales	201174|Actinobacteria	S	Psort location Cytoplasmic, score 8.87	mazG	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0022607,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0035539,GO:0042454,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044464,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0047693,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.6.1.66	ko:K02428,ko:K02499	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG
IOLKFBCL_00559	1437603.BMON_0921	1.38e-130	392.0	COG0582@1|root,COG0582@2|Bacteria,2HZF9@201174|Actinobacteria,4D08E@85004|Bifidobacteriales	201174|Actinobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
IOLKFBCL_00560	1437603.BMON_0174	9.2e-68	208.0	COG3600@1|root,COG3600@2|Bacteria,2IQQG@201174|Actinobacteria,4D1B8@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF4065)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4065
IOLKFBCL_00561	1137268.AZXF01000014_gene78	4.56e-21	90.1	2EJIH@1|root,33D9E@2|Bacteria,2GVQK@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00573	523841.HFX_0150	3.13e-15	82.8	COG0330@1|root,arCOG01915@2157|Archaea,2XTT5@28890|Euryarchaeota,23UP1@183963|Halobacteria	183963|Halobacteria	O	COG0330 Membrane protease subunits, stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
IOLKFBCL_00575	1123065.ATWL01000002_gene1767	0.000157	44.7	COG3599@1|root,COG3599@2|Bacteria,2GMSC@201174|Actinobacteria	201174|Actinobacteria	D	Cell division initiation protein	wag31	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0022603,GO:0022604,GO:0030312,GO:0031647,GO:0040007,GO:0042546,GO:0044085,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0050821,GO:0051128,GO:0060187,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944	-	-	-	-	-	-	-	-	-	-	DivIVA
IOLKFBCL_00576	1687.BCOR_0988	2.52e-85	263.0	2B5FA@1|root,31Y9U@2|Bacteria,2HZSN@201174|Actinobacteria,4D1JW@85004|Bifidobacteriales	201174|Actinobacteria	L	PDDEXK-like domain of unknown function (DUF3799)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3799
IOLKFBCL_00578	883067.HMPREF9237_00388	4.21e-07	55.8	COG0629@1|root,COG0629@2|Bacteria,2GMM3@201174|Actinobacteria,4D497@85005|Actinomycetales	201174|Actinobacteria	L	Single-stranded DNA-binding protein	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
IOLKFBCL_00579	1437603.BMON_1161	6.26e-42	141.0	COG1403@1|root,COG1403@2|Bacteria,2GQKB@201174|Actinobacteria,4D1JQ@85004|Bifidobacteriales	201174|Actinobacteria	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00585	1115632.JAFW01000001_gene426	1.02e-65	204.0	COG1041@1|root,COG1041@2|Bacteria,2I7CG@201174|Actinobacteria,1WBI3@1268|Micrococcaceae	201174|Actinobacteria	L	tRNA (guanine-N2-)-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00594	1089546.AQUI01000001_gene38	3.61e-10	58.2	2DMIE@1|root,32RSG@2|Bacteria,2IQCG@201174|Actinobacteria,40A9Z@622450|Actinopolysporales	201174|Actinobacteria	K	Transcription factor WhiB	whiB	GO:0000302,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0010035,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0015035,GO:0015036,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042221,GO:0042493,GO:0045892,GO:0045934,GO:0047134,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0060255,GO:0065007,GO:0071731,GO:0080090,GO:0097159,GO:0097366,GO:1901363,GO:1901698,GO:1901700,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
IOLKFBCL_00605	1394176.AWUO01000014_gene675	1.81e-50	175.0	2DRSV@1|root,33CWS@2|Bacteria,2GRW4@201174|Actinobacteria,4D1IT@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00606	1437605.BACT_1092	1.45e-32	120.0	2B50E@1|root,31XTI@2|Bacteria,2GZMU@201174|Actinobacteria,4D1QR@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00608	702459.BBPR_0883	1.33e-90	275.0	COG3617@1|root,COG3645@1|root,COG3617@2|Bacteria,COG3645@2|Bacteria,2IMZ0@201174|Actinobacteria,4D0PU@85004|Bifidobacteriales	201174|Actinobacteria	K	BRO family, N-terminal domain	-	-	-	ko:K07741	-	-	-	-	ko00000	-	-	-	ANT,Bro-N
IOLKFBCL_00611	748224.HMPREF9436_03071	8.42e-44	154.0	2F1QX@1|root,33UR3@2|Bacteria,1VUWE@1239|Firmicutes,24HRU@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00616	1394176.AWUO01000014_gene645	1.25e-53	183.0	COG4974@1|root,COG4974@2|Bacteria,2ID5W@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
IOLKFBCL_00621	762211.BSTEL_0268	4.84e-65	199.0	COG2337@1|root,COG2337@2|Bacteria,2ISK5@201174|Actinobacteria,4D1AT@85004|Bifidobacteriales	201174|Actinobacteria	T	Toxic component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00622	762211.BSTEL_0269	5.17e-46	149.0	COG3077@1|root,COG3077@2|Bacteria,2GRAY@201174|Actinobacteria,4D1J9@85004|Bifidobacteriales	201174|Actinobacteria	L	RelB antitoxin	-	-	-	ko:K07473	-	-	-	-	ko00000,ko02048	-	-	-	RelB
IOLKFBCL_00631	762211.BSTEL_0947	1.26e-18	79.0	29ZI4@1|root,30MI7@2|Bacteria,2GWTX@201174|Actinobacteria	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
IOLKFBCL_00633	216816.GS08_09425	2.12e-188	524.0	COG1414@1|root,COG1414@2|Bacteria,2GPS1@201174|Actinobacteria,4D25V@85004|Bifidobacteriales	201174|Actinobacteria	K	Bacterial transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
IOLKFBCL_00634	216816.GS08_09420	1.49e-170	477.0	COG1414@1|root,COG1414@2|Bacteria,2IMT9@201174|Actinobacteria,4D1ZU@85004|Bifidobacteriales	201174|Actinobacteria	K	Sugar-specific transcriptional regulator TrmB	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
IOLKFBCL_00635	216816.GS08_09415	1.32e-177	497.0	COG2508@1|root,COG2508@2|Bacteria,2GN0S@201174|Actinobacteria,4CYXU@85004|Bifidobacteriales	201174|Actinobacteria	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
IOLKFBCL_00636	216816.GS08_09410	0.0	1320.0	2DX0J@1|root,342TV@2|Bacteria,2H683@201174|Actinobacteria,4CZAG@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00637	216816.GS08_09405	2.25e-190	531.0	COG0340@1|root,COG0340@2|Bacteria,2GN8Q@201174|Actinobacteria,4D0R8@85004|Bifidobacteriales	201174|Actinobacteria	H	Biotin/lipoate A/B protein ligase family	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB
IOLKFBCL_00638	216816.GS08_09400	7.91e-19	84.7	COG1268@1|root,COG1268@2|Bacteria,2GJ53@201174|Actinobacteria,4D0BB@85004|Bifidobacteriales	201174|Actinobacteria	S	BioY family	bioY	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
IOLKFBCL_00639	216816.GS08_09395	0.0	1250.0	COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria,4CYU4@85004|Bifidobacteriales	201174|Actinobacteria	I	Carbamoyl-phosphate synthase L chain, ATP binding domain protein	accC	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
IOLKFBCL_00640	216816.GS08_09390	0.0	1032.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4CYSI@85004|Bifidobacteriales	201174|Actinobacteria	I	Carboxyl transferase domain	pccB	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
IOLKFBCL_00641	216816.GS08_09385	0.0	5949.0	COG0304@1|root,COG0331@1|root,COG2030@1|root,COG4981@1|root,COG0304@2|Bacteria,COG0331@2|Bacteria,COG2030@2|Bacteria,COG4981@2|Bacteria,2GIY4@201174|Actinobacteria,4CYXJ@85004|Bifidobacteriales	201174|Actinobacteria	I	Beta-ketoacyl synthase, C-terminal domain	fas	-	-	ko:K11533	ko00061,ko01100,ko01212,ko04931,map00061,map01100,map01212,map04931	M00082,M00083	R01624,R01626,R04355,R04428,R04429,R04533,R04534,R04535,R04536,R04537,R04543,R04544,R04566,R04568,R04724,R04726,R04952,R04953,R04954,R04955,R04957,R04958,R04960,R04961,R04963,R04964,R04965,R04966,R04968,R04969,R07762,R07763,R07764,R07765,R10700	RC00004,RC00029,RC00039,RC00052,RC00076,RC00117,RC00831,RC01095,RC02727,RC02728,RC02729,RC02857,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1,DUF1729,Ketoacyl-synt_C,MaoC_dehydratas,SAT,ketoacyl-synt
IOLKFBCL_00642	216816.GS08_09370	2.89e-123	352.0	COG0736@1|root,COG0736@2|Bacteria,2HZNB@201174|Actinobacteria,4D10J@85004|Bifidobacteriales	201174|Actinobacteria	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
IOLKFBCL_00643	216816.GS08_09365	2.79e-32	112.0	COG0366@1|root,COG0366@2|Bacteria	2|Bacteria	G	hydrolase activity, hydrolyzing O-glycosyl compounds	dexB	-	2.4.1.7,3.2.1.20,3.2.1.51,3.2.1.70,3.2.1.93,3.2.1.97	ko:K00690,ko:K01187,ko:K01206,ko:K01215,ko:K01226,ko:K17624	ko00052,ko00500,ko00511,ko01100,map00052,map00500,map00511,map01100	-	R00028,R00801,R00802,R00803,R00837,R06087,R06088,R06113	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000,ko04147	-	GH101,GH13,GH29,GH31	-	Alpha-amylase,Alpha_L_fucos,CBM_35,F5_F8_type_C,NPCBM_assoc,SLH
IOLKFBCL_00645	326426.Bbr_0363	1.23e-09	58.9	2C89M@1|root,332IE@2|Bacteria,2IPVJ@201174|Actinobacteria,4D133@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00646	326426.Bbr_0363	7.07e-103	300.0	2C89M@1|root,332IE@2|Bacteria,2IPVJ@201174|Actinobacteria,4D133@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00647	216816.GS08_09350	0.0	2154.0	COG1361@1|root,COG1361@2|Bacteria,2GYAW@201174|Actinobacteria,4D2X8@85004|Bifidobacteriales	201174|Actinobacteria	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,FctA,VWA,VWA_2
IOLKFBCL_00648	566552.BIFCAT_00128	2.13e-128	391.0	COG4932@1|root,COG4932@2|Bacteria,2IBAM@201174|Actinobacteria,4D0B6@85004|Bifidobacteriales	201174|Actinobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GramPos_pilinBB,Gram_pos_anchor
IOLKFBCL_00649	746697.Aeqsu_2314	9.61e-120	373.0	COG2159@1|root,COG2159@2|Bacteria,4NSBH@976|Bacteroidetes,1IICU@117743|Flavobacteriia	976|Bacteroidetes	S	AIPR protein	-	-	-	-	-	-	-	-	-	-	-	-	AIPR
IOLKFBCL_00650	326426.Bbr_0368	7.59e-108	311.0	2DNNA@1|root,32Y8E@2|Bacteria,2ISEY@201174|Actinobacteria,4D1A0@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00651	216816.GS08_09325	2.56e-151	426.0	2B37S@1|root,31VVT@2|Bacteria,2IDBE@201174|Actinobacteria,4CZJV@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00652	1437610.BREU_1625	2.49e-231	644.0	COG3464@1|root,COG3464@2|Bacteria,2IP45@201174|Actinobacteria,4D04T@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
IOLKFBCL_00653	326426.Bbr_0966	1.08e-120	348.0	COG0400@1|root,COG0400@2|Bacteria,2GNIF@201174|Actinobacteria,4D0TH@85004|Bifidobacteriales	201174|Actinobacteria	S	Phospholipase/Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
IOLKFBCL_00654	216816.GS08_04905	5.15e-247	679.0	COG2519@1|root,COG2519@2|Bacteria,2GJPD@201174|Actinobacteria,4CYUG@85004|Bifidobacteriales	201174|Actinobacteria	J	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA	trmI	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0031515,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.219,2.1.1.220	ko:K07442	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	GCD14,GCD14_N
IOLKFBCL_00655	216816.GS08_04910	3.11e-124	354.0	COG2062@1|root,COG2062@2|Bacteria,2GJ0I@201174|Actinobacteria,4D05N@85004|Bifidobacteriales	201174|Actinobacteria	T	Phosphoglycerate mutase family	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
IOLKFBCL_00656	326426.Bbr_0969	0.0	1451.0	COG0620@1|root,COG0620@2|Bacteria,2GIXA@201174|Actinobacteria,4CYWM@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	metE	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0040007,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_1,Meth_synt_2
IOLKFBCL_00657	216816.GS08_04920	6.39e-198	549.0	COG0685@1|root,COG0685@2|Bacteria,2GJTN@201174|Actinobacteria,4CZ22@85004|Bifidobacteriales	201174|Actinobacteria	E	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
IOLKFBCL_00658	326426.Bbr_0971	9.88e-239	655.0	COG3049@1|root,COG3049@2|Bacteria,2GK9Z@201174|Actinobacteria,4CZNU@85004|Bifidobacteriales	201174|Actinobacteria	M	Linear amide C-N hydrolase, choloylglycine hydrolase family protein	cbh	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	CBAH
IOLKFBCL_00659	216816.GS08_04930	0.0	1992.0	COG1391@1|root,COG1391@2|Bacteria,2GJ91@201174|Actinobacteria,4CYQE@85004|Bifidobacteriales	201174|Actinobacteria	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
IOLKFBCL_00660	216816.GS08_04935	4.82e-227	625.0	COG0540@1|root,COG0540@2|Bacteria,2GKNA@201174|Actinobacteria,4CYZR@85004|Bifidobacteriales	201174|Actinobacteria	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
IOLKFBCL_00661	216816.GS08_04940	3.7e-96	280.0	COG1781@1|root,COG1781@2|Bacteria,2IFDF@201174|Actinobacteria,4D0QN@85004|Bifidobacteriales	201174|Actinobacteria	F	Aspartate carbamoyltransferase regulatory chain, allosteric domain protein	pyrI	-	-	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002	-	-	-	PyrI,PyrI_C
IOLKFBCL_00662	216816.GS08_04945	0.0	988.0	COG0044@1|root,COG0044@2|Bacteria,2GJ0T@201174|Actinobacteria,4CZIW@85004|Bifidobacteriales	201174|Actinobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
IOLKFBCL_00663	216816.GS08_04950	1.74e-223	616.0	COG0284@1|root,COG0284@2|Bacteria,2GKWK@201174|Actinobacteria,4CZAK@85004|Bifidobacteriales	201174|Actinobacteria	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
IOLKFBCL_00664	216816.GS08_04955	2.74e-203	561.0	COG0543@1|root,COG0543@2|Bacteria,2HQ24@201174|Actinobacteria,4CZC1@85004|Bifidobacteriales	201174|Actinobacteria	C	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
IOLKFBCL_00665	216816.GS08_04960	3.42e-233	641.0	COG0167@1|root,COG0167@2|Bacteria,2GKC6@201174|Actinobacteria,4CYU2@85004|Bifidobacteriales	201174|Actinobacteria	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
IOLKFBCL_00666	216816.GS08_04965	1.33e-159	447.0	COG0461@1|root,COG0461@2|Bacteria,2GM5A@201174|Actinobacteria,4CZHB@85004|Bifidobacteriales	201174|Actinobacteria	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
IOLKFBCL_00667	216816.GS08_04970	1.08e-39	131.0	2B3KJ@1|root,31W9X@2|Bacteria,2GWXF@201174|Actinobacteria,4D1NA@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00668	326426.Bbr_0980	1.51e-259	712.0	COG1073@1|root,COG1073@2|Bacteria,2GMT6@201174|Actinobacteria,4CZ4Q@85004|Bifidobacteriales	201174|Actinobacteria	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF2974
IOLKFBCL_00669	326426.Bbr_0981	2.56e-220	607.0	COG0583@1|root,COG0583@2|Bacteria,2HZCU@201174|Actinobacteria,4CZT8@85004|Bifidobacteriales	201174|Actinobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
IOLKFBCL_00670	1437609.BCAL_0231	1.3e-87	277.0	COG1132@1|root,COG1132@2|Bacteria,2ICTY@201174|Actinobacteria,4D0II@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
IOLKFBCL_00671	216816.GS08_04985	3.74e-155	434.0	COG1011@1|root,COG1011@2|Bacteria,2I8XE@201174|Actinobacteria,4D00B@85004|Bifidobacteriales	201174|Actinobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	3.8.1.2	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
IOLKFBCL_00672	216816.GS08_04990	0.0	1102.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2GJHB@201174|Actinobacteria,4CZC5@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
IOLKFBCL_00673	216816.GS08_04995	3.24e-293	799.0	COG0436@1|root,COG0436@2|Bacteria,2GPM3@201174|Actinobacteria,4CZ6T@85004|Bifidobacteriales	201174|Actinobacteria	E	Psort location Cytoplasmic, score 8.87	-	-	2.6.1.1	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
IOLKFBCL_00674	1437609.BCAL_1839	1.44e-140	433.0	COG1061@1|root,COG4951@1|root,COG1061@2|Bacteria,COG4951@2|Bacteria,2GIR9@201174|Actinobacteria,4D2TF@85004|Bifidobacteriales	201174|Actinobacteria	KL	DEAD-like helicases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Helicase_C,Lsr2,ResIII
IOLKFBCL_00675	1437610.BREU_1592	8.97e-73	245.0	COG1061@1|root,COG4951@1|root,COG1061@2|Bacteria,COG4951@2|Bacteria,2GIR9@201174|Actinobacteria,4D2TF@85004|Bifidobacteriales	201174|Actinobacteria	KL	DEAD-like helicases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Helicase_C,Lsr2,ResIII
IOLKFBCL_00676	216816.GS08_05005	1.92e-58	181.0	COG3189@1|root,COG3189@2|Bacteria,2IQC0@201174|Actinobacteria,4D18P@85004|Bifidobacteriales	201174|Actinobacteria	K	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
IOLKFBCL_00678	450380.JPSY01000001_gene1521	3.89e-05	46.6	COG3654@1|root,COG3943@1|root,COG3654@2|Bacteria,COG3943@2|Bacteria,2IA5J@201174|Actinobacteria,4FQY1@85023|Microbacteriaceae	201174|Actinobacteria	S	Virulence protein RhuM family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Virulence_RhuM
IOLKFBCL_00679	1693.BMIN_1405	1.45e-72	230.0	COG3654@1|root,COG3943@1|root,COG3654@2|Bacteria,COG3943@2|Bacteria,2IA5J@201174|Actinobacteria,4D0WF@85004|Bifidobacteriales	201174|Actinobacteria	S	Virulence protein RhuM family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Virulence_RhuM
IOLKFBCL_00681	326426.Bbr_1095	6.36e-21	88.2	COG3738@1|root,COG3738@2|Bacteria,2IBMJ@201174|Actinobacteria,4CZM2@85004|Bifidobacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF1287)	-	-	-	ko:K09974	-	-	-	-	ko00000	-	-	-	DUF1287
IOLKFBCL_00682	326426.Bbr_1094	1.69e-200	561.0	COG2865@1|root,COG2865@2|Bacteria,2IF0U@201174|Actinobacteria,4D0I9@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00683	326426.Bbr_1093	3.4e-98	285.0	2ATA8@1|root,31IT9@2|Bacteria,2IICV@201174|Actinobacteria,4D0W4@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00684	326426.Bbr_1092	4.1e-84	248.0	COG3189@1|root,COG3189@2|Bacteria,2IQC0@201174|Actinobacteria,4D18P@85004|Bifidobacteriales	201174|Actinobacteria	K	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
IOLKFBCL_00685	326426.Bbr_1091	5.32e-11	60.1	2B5AB@1|root,31YAH@2|Bacteria,2HZT2@201174|Actinobacteria,4D1NJ@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00686	216816.GS08_10280	0.0	1083.0	COG1511@1|root,COG1511@2|Bacteria,2GKEM@201174|Actinobacteria,4CZ2A@85004|Bifidobacteriales	201174|Actinobacteria	S	YhgE Pip domain protein	-	-	-	ko:K01421	-	-	-	-	ko00000	-	-	-	ABC2_membrane,ABC2_membrane_3,DUF3533
IOLKFBCL_00687	216816.GS08_10275	0.0	1426.0	COG1511@1|root,COG1511@2|Bacteria,2GKEM@201174|Actinobacteria,4CZ9R@85004|Bifidobacteriales	201174|Actinobacteria	S	YhgE Pip domain protein	-	-	-	ko:K01421	-	-	-	-	ko00000	-	-	-	ABC2_membrane_3,DUF3533
IOLKFBCL_00688	216816.GS08_10270	6.35e-181	503.0	COG0778@1|root,COG0778@2|Bacteria,2I65Z@201174|Actinobacteria,4CZ5R@85004|Bifidobacteriales	201174|Actinobacteria	C	Nitroreductase family	nfrA	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
IOLKFBCL_00689	216816.GS08_10265	5.29e-78	233.0	2B5DJ@1|root,31Y80@2|Bacteria,2IRRR@201174|Actinobacteria,4D1E6@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF4235)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4235
IOLKFBCL_00690	216816.GS08_10260	3.42e-174	485.0	COG0406@1|root,COG0406@2|Bacteria,2GNRS@201174|Actinobacteria,4CZD2@85004|Bifidobacteriales	201174|Actinobacteria	G	Phosphoglycerate mutase family	gpm2	GO:0003674,GO:0003824,GO:0003993,GO:0005488,GO:0005515,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0042802,GO:0042803,GO:0044237,GO:0046983	3.1.3.73	ko:K02226	ko00860,ko01100,map00860,map01100	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
IOLKFBCL_00691	216816.GS08_10255	3.71e-316	861.0	COG1653@1|root,COG1653@2|Bacteria,2GWCY@201174|Actinobacteria,4CYWG@85004|Bifidobacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	amyE	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_8
IOLKFBCL_00692	216816.GS08_10250	7.73e-233	642.0	COG1609@1|root,COG1609@2|Bacteria,2GJBJ@201174|Actinobacteria,4CZ1Y@85004|Bifidobacteriales	201174|Actinobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
IOLKFBCL_00693	216816.GS08_10245	9.46e-200	553.0	COG1175@1|root,COG1175@2|Bacteria,2I330@201174|Actinobacteria,4CZJC@85004|Bifidobacteriales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	msmF	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
IOLKFBCL_00694	216816.GS08_10240	3.69e-195	541.0	COG0395@1|root,COG0395@2|Bacteria,2GJNN@201174|Actinobacteria,4CYZ9@85004|Bifidobacteriales	201174|Actinobacteria	G	ABC transporter permease	-	-	-	ko:K02026,ko:K10119	ko02010,map02010	M00196,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.28	-	-	BPD_transp_1
IOLKFBCL_00695	216816.GS08_10235	4.7e-136	385.0	COG5578@1|root,COG5578@2|Bacteria,2IBKF@201174|Actinobacteria,4D0E0@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function, DUF624	-	-	-	-	-	-	-	-	-	-	-	-	DUF624
IOLKFBCL_00696	216816.GS08_09320	1.65e-93	278.0	COG3464@1|root,COG3464@2|Bacteria,2IP45@201174|Actinobacteria,4D04T@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
IOLKFBCL_00697	216816.GS08_10225	0.0	949.0	COG1672@1|root,COG1672@2|Bacteria,2GMAZ@201174|Actinobacteria,4D00I@85004|Bifidobacteriales	201174|Actinobacteria	S	ATPase domain predominantly from Archaea	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	ATPase_2,DUF234,HTH_IclR
IOLKFBCL_00698	216816.GS08_10220	0.0	934.0	COG1113@1|root,COG1113@2|Bacteria,2GJ0X@201174|Actinobacteria,4CZ4X@85004|Bifidobacteriales	201174|Actinobacteria	E	aromatic amino acid transport protein AroP K03293	aroP	-	-	ko:K03293,ko:K11732	-	-	-	-	ko00000,ko02000	2.A.3.1,2.A.3.1.1	-	-	AA_permease
IOLKFBCL_00699	216816.GS08_10215	7.06e-132	374.0	COG1309@1|root,COG1309@2|Bacteria,2HZBI@201174|Actinobacteria,4CZJ8@85004|Bifidobacteriales	201174|Actinobacteria	K	Transcriptional regulator C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
IOLKFBCL_00700	216816.GS08_10210	1.44e-164	460.0	COG1136@1|root,COG1136@2|Bacteria,2GJQV@201174|Actinobacteria,4CYT2@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IOLKFBCL_00701	216816.GS08_10205	0.0	1771.0	COG0577@1|root,COG1511@1|root,COG0577@2|Bacteria,COG1511@2|Bacteria,2I2FK@201174|Actinobacteria,4CZJR@85004|Bifidobacteriales	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
IOLKFBCL_00702	216816.GS08_10145	0.0	924.0	COG1113@1|root,COG1113@2|Bacteria,2GJ0X@201174|Actinobacteria,4CZAY@85004|Bifidobacteriales	201174|Actinobacteria	E	Amino acid permease	-	-	-	ko:K03293	-	-	-	-	ko00000	2.A.3.1	-	-	AA_permease
IOLKFBCL_00703	216816.GS08_10120	2.11e-101	296.0	COG1846@1|root,COG1846@2|Bacteria,2IMKE@201174|Actinobacteria,4CYZZ@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_34,MarR
IOLKFBCL_00704	216816.GS08_10115	0.0	1108.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4CYYV@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter, ATP-binding protein	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
IOLKFBCL_00705	216816.GS08_10110	0.0	1143.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4CZTU@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
IOLKFBCL_00706	216816.GS08_10105	4.38e-205	572.0	COG1477@1|root,COG1477@2|Bacteria,2H8YU@201174|Actinobacteria,4CZW7@85004|Bifidobacteriales	201174|Actinobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
IOLKFBCL_00710	326426.Bbr_0152	7.49e-243	674.0	COG4584@1|root,COG4584@2|Bacteria,2IBDV@201174|Actinobacteria,4CZS6@85004|Bifidobacteriales	201174|Actinobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve
IOLKFBCL_00711	356829.BITS_1852	1.93e-17	85.1	2B5EX@1|root,31Y9E@2|Bacteria,2H0ER@201174|Actinobacteria,4D1TB@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00713	402777.KB235903_gene2198	1.22e-18	92.0	COG0331@1|root,COG0331@2|Bacteria,1FZZ5@1117|Cyanobacteria,1H7PP@1150|Oscillatoriales	1117|Cyanobacteria	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
IOLKFBCL_00714	764298.STRMA_1488	1.71e-176	543.0	COG3321@1|root,COG3321@2|Bacteria,1VU8Z@1239|Firmicutes,4HDNB@91061|Bacilli	91061|Bacilli	Q	Ketoacyl-synthetase C-terminal extension	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,KAsynt_C_assoc,Ketoacyl-synt_C,PP-binding,ketoacyl-synt
IOLKFBCL_00715	764298.STRMA_1489	1.62e-143	462.0	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,4HAHU@91061|Bacilli	91061|Bacilli	Q	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,NAD_binding_4,PP-binding
IOLKFBCL_00716	216816.GS08_10090	1.04e-233	644.0	COG0313@1|root,COG0313@2|Bacteria,2GJ9Q@201174|Actinobacteria,4CZ03@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:1901360	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
IOLKFBCL_00717	216816.GS08_10080	1.4e-145	410.0	2AU2N@1|root,31JNZ@2|Bacteria,2IJNI@201174|Actinobacteria,4D047@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00718	216816.GS08_10075	0.0	1248.0	COG0143@1|root,COG0143@2|Bacteria,2GK4S@201174|Actinobacteria,4CZ20@85004|Bifidobacteriales	201174|Actinobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g
IOLKFBCL_00719	326426.Bbr_1819	1.37e-58	181.0	2AWD6@1|root,31N94@2|Bacteria,2IP9F@201174|Actinobacteria,4D137@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00720	1435051.BMOU_0550	8.72e-184	526.0	COG1653@1|root,COG1653@2|Bacteria,2I8SG@201174|Actinobacteria,4CZ4S@85004|Bifidobacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K17318	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	SBP_bac_1,SBP_bac_8
IOLKFBCL_00721	1435051.BMOU_0549	2.2e-192	538.0	COG4209@1|root,COG4209@2|Bacteria,2GKSR@201174|Actinobacteria,4CZIC@85004|Bifidobacteriales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17319	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
IOLKFBCL_00722	1435051.BMOU_0548	1.39e-194	543.0	COG0395@1|root,COG0395@2|Bacteria,2GJPQ@201174|Actinobacteria,4CYTJ@85004|Bifidobacteriales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17320	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
IOLKFBCL_00723	445975.COLSTE_02537	1.18e-35	142.0	2AHMW@1|root,317ZU@2|Bacteria,2HC22@201174|Actinobacteria	201174|Actinobacteria	S	Unextendable partial coding region	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00724	216816.GS08_06950	0.0	1300.0	COG4716@1|root,COG4716@2|Bacteria,2GKZ8@201174|Actinobacteria,4CYZK@85004|Bifidobacteriales	201174|Actinobacteria	S	MCRA family	-	-	4.2.1.53	ko:K10254	-	-	-	-	ko00000,ko01000	-	-	-	MCRA
IOLKFBCL_00725	216816.GS08_06955	1.83e-98	286.0	2DMJC@1|root,32RYJ@2|Bacteria,2IHZV@201174|Actinobacteria,4D0UY@85004|Bifidobacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4186)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4186
IOLKFBCL_00726	216816.GS08_06960	0.0	2366.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4CZKT@85004|Bifidobacteriales	201174|Actinobacteria	L	DNA polymerase III alpha subunit	dnaE	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
IOLKFBCL_00727	216816.GS08_06965	2.75e-166	468.0	COG1295@1|root,COG1295@2|Bacteria,2GN79@201174|Actinobacteria,4CZM4@85004|Bifidobacteriales	201174|Actinobacteria	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
IOLKFBCL_00728	698961.CGSMWGv6119V5_00927	4e-127	402.0	COG4652@1|root,COG4652@2|Bacteria,2I8H1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00729	700015.Corgl_0802	9.81e-68	215.0	COG1136@1|root,COG1136@2|Bacteria,2IAY5@201174|Actinobacteria,4CXQ0@84998|Coriobacteriia	84998|Coriobacteriia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IOLKFBCL_00730	216816.GS08_06970	2.49e-229	631.0	COG0564@1|root,COG0564@2|Bacteria,2GIY1@201174|Actinobacteria,4CYYR@85004|Bifidobacteriales	201174|Actinobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluD	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
IOLKFBCL_00731	216816.GS08_06975	8.56e-116	333.0	COG0597@1|root,COG0597@2|Bacteria,2GKRX@201174|Actinobacteria,4D0WR@85004|Bifidobacteriales	201174|Actinobacteria	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
IOLKFBCL_00732	216816.GS08_06980	6.92e-142	421.0	COG1566@1|root,COG1566@2|Bacteria,2I2G9@201174|Actinobacteria,4CZ5W@85004|Bifidobacteriales	201174|Actinobacteria	V	DivIVA protein	-	-	-	-	-	-	-	-	-	-	-	-	DivIVA
IOLKFBCL_00733	216816.GS08_06985	3.18e-56	176.0	COG0762@1|root,COG0762@2|Bacteria,2GQI1@201174|Actinobacteria,4D17B@85004|Bifidobacteriales	201174|Actinobacteria	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
IOLKFBCL_00734	216816.GS08_06990	2.78e-103	299.0	COG1799@1|root,COG1799@2|Bacteria,2GNVH@201174|Actinobacteria,4D0RJ@85004|Bifidobacteriales	201174|Actinobacteria	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
IOLKFBCL_00735	216816.GS08_06995	1.5e-259	714.0	COG0206@1|root,COG0206@2|Bacteria,2GJWC@201174|Actinobacteria,4CZ10@85004|Bifidobacteriales	201174|Actinobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	GO:0000166,GO:0000287,GO:0000910,GO:0000921,GO:0000935,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022402,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032155,GO:0032185,GO:0032506,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0045787,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051258,GO:0051301,GO:0051726,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
IOLKFBCL_00736	326426.Bbr_1304	1.08e-304	830.0	COG0042@1|root,COG0042@2|Bacteria,2GJ8I@201174|Actinobacteria,4CZFD@85004|Bifidobacteriales	201174|Actinobacteria	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	GO:0008150,GO:0010565,GO:0019216,GO:0019217,GO:0019222,GO:0031323,GO:0050789,GO:0050794,GO:0062012,GO:0065007,GO:0080090	-	-	-	-	-	-	-	-	-	-	Dus
IOLKFBCL_00737	216816.GS08_07005	0.0	1025.0	COG0423@1|root,COG0423@2|Bacteria,2GIT3@201174|Actinobacteria,4CYZU@85004|Bifidobacteriales	201174|Actinobacteria	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
IOLKFBCL_00738	216816.GS08_07010	3.06e-211	585.0	COG2145@1|root,COG2145@2|Bacteria,2IC73@201174|Actinobacteria,4CZU8@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)	thiM	-	2.7.1.50	ko:K00878	ko00730,ko01100,map00730,map01100	M00127	R04448	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HK
IOLKFBCL_00739	216816.GS08_07015	0.0	1816.0	COG0352@1|root,COG0422@1|root,COG0352@2|Bacteria,COG0422@2|Bacteria,2GJ3Y@201174|Actinobacteria,4D2W5@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016020,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0040007,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
IOLKFBCL_00740	216816.GS08_07020	5.8e-290	791.0	COG1222@1|root,COG1222@2|Bacteria,2I5C1@201174|Actinobacteria,4D0DP@85004|Bifidobacteriales	201174|Actinobacteria	O	AAA domain (Cdc48 subfamily)	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA
IOLKFBCL_00741	216816.GS08_07025	1.24e-186	519.0	COG0351@1|root,COG0351@2|Bacteria,2GKZM@201174|Actinobacteria,4CYQA@85004|Bifidobacteriales	201174|Actinobacteria	H	Phosphomethylpyrimidine kinase	thiD	GO:0008150,GO:0040007	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
IOLKFBCL_00742	216816.GS08_07030	2.73e-80	238.0	COG0011@1|root,COG0011@2|Bacteria,2IQ7E@201174|Actinobacteria,4D14E@85004|Bifidobacteriales	201174|Actinobacteria	S	Thiamine-binding protein	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
IOLKFBCL_00743	216816.GS08_07040	3.71e-86	269.0	COG4585@1|root,COG4585@2|Bacteria,2I370@201174|Actinobacteria,4D0JE@85004|Bifidobacteriales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00744	216816.GS08_07050	2.35e-23	98.2	2CK5B@1|root,2ZYDK@2|Bacteria,2HU05@201174|Actinobacteria,4D0JT@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00745	326426.Bbr_1320	0.0	868.0	COG4826@1|root,COG4826@2|Bacteria,2GJ5T@201174|Actinobacteria,4D0C1@85004|Bifidobacteriales	201174|Actinobacteria	O	SERine  Proteinase INhibitors	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
IOLKFBCL_00746	216816.GS08_07060	2.17e-243	669.0	COG1609@1|root,COG1609@2|Bacteria,2GJY9@201174|Actinobacteria,4CYU5@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
IOLKFBCL_00747	1680.BADO_1282	6.47e-303	828.0	COG2807@1|root,COG2807@2|Bacteria,2GJRD@201174|Actinobacteria,4CYTK@85004|Bifidobacteriales	201174|Actinobacteria	P	LacY proton/sugar symporter	lacY	-	-	ko:K02532	-	-	-	-	ko00000,ko02000	2.A.1.5	-	-	LacY_symp
IOLKFBCL_00748	326426.Bbr_1324	0.0	1039.0	COG1621@1|root,COG1621@2|Bacteria,2GJ9T@201174|Actinobacteria,4CZ8W@85004|Bifidobacteriales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 32 family	fosC	-	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32C,Glyco_hydro_32N
IOLKFBCL_00749	216816.GS08_07080	3.12e-177	494.0	COG0600@1|root,COG0600@2|Bacteria,2GKKZ@201174|Actinobacteria,4CZ9Q@85004|Bifidobacteriales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
IOLKFBCL_00750	216816.GS08_07085	1.63e-259	711.0	COG0715@1|root,COG0715@2|Bacteria,2HZ9T@201174|Actinobacteria,4CZ56@85004|Bifidobacteriales	201174|Actinobacteria	P	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
IOLKFBCL_00751	1437610.BREU_0334	2.74e-265	729.0	COG1957@1|root,COG1957@2|Bacteria,2I9SG@201174|Actinobacteria,4CZWE@85004|Bifidobacteriales	201174|Actinobacteria	F	nucleoside hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	IU_nuc_hydro
IOLKFBCL_00752	216816.GS08_07095	4.53e-196	542.0	COG0020@1|root,COG0020@2|Bacteria,2GIXF@201174|Actinobacteria,4CZAR@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008834,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0050347,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617	2.5.1.31,2.5.1.86,2.5.1.88	ko:K00806,ko:K14215,ko:K21273	ko00900,ko01110,map00900,map01110	-	R06447,R09244,R09731	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
IOLKFBCL_00753	216816.GS08_07100	7.4e-145	411.0	COG1381@1|root,COG1381@2|Bacteria,2GK81@201174|Actinobacteria,4CZCN@85004|Bifidobacteriales	201174|Actinobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
IOLKFBCL_00754	216816.GS08_07105	0.0	978.0	COG0657@1|root,COG0657@2|Bacteria,2I2GD@201174|Actinobacteria,4CZUD@85004|Bifidobacteriales	201174|Actinobacteria	I	acetylesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00755	216816.GS08_07110	1.14e-294	804.0	COG0821@1|root,COG0821@2|Bacteria,2GK2S@201174|Actinobacteria,4CYQB@85004|Bifidobacteriales	201174|Actinobacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030312,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
IOLKFBCL_00756	216816.GS08_07115	1.28e-274	752.0	COG0743@1|root,COG0743@2|Bacteria,2GIRV@201174|Actinobacteria,4CZVC@85004|Bifidobacteriales	201174|Actinobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0050897,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2870c	DXPR_C,DXP_redisom_C,DXP_reductoisom
IOLKFBCL_00757	216816.GS08_07120	0.0	951.0	COG3170@1|root,COG3170@2|Bacteria,2I2GE@201174|Actinobacteria,4CZDF@85004|Bifidobacteriales	201174|Actinobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00759	216816.GS08_07135	2.15e-65	202.0	2B57P@1|root,31Y1M@2|Bacteria,2IFRB@201174|Actinobacteria,4D307@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3052)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3052
IOLKFBCL_00760	216816.GS08_07140	4.86e-202	560.0	COG3480@1|root,COG3480@2|Bacteria,2GMFX@201174|Actinobacteria,4CYUP@85004|Bifidobacteriales	201174|Actinobacteria	T	Belongs to the peptidase S16 family	sdrC	-	-	ko:K07177	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	Lon_C
IOLKFBCL_00761	216816.GS08_07145	0.0	1081.0	COG5282@1|root,COG5282@2|Bacteria,2GJ9K@201174|Actinobacteria,4CYU7@85004|Bifidobacteriales	201174|Actinobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_2
IOLKFBCL_00762	216816.GS08_07150	0.0	1000.0	COG0210@1|root,COG0210@2|Bacteria,2GKRW@201174|Actinobacteria,4CZ3A@85004|Bifidobacteriales	201174|Actinobacteria	L	DNA helicase	uvrD2	GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0006996,GO:0008094,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0040007,GO:0042623,GO:0043167,GO:0043169,GO:0046872,GO:0051276,GO:0071103,GO:0071840,GO:0140097	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HRDC,UvrD-helicase,UvrD_C
IOLKFBCL_00763	216816.GS08_07155	0.0	1040.0	COG3173@1|root,COG3173@2|Bacteria,2I8R6@201174|Actinobacteria,4CYPR@85004|Bifidobacteriales	201174|Actinobacteria	S	Aminoglycoside phosphotransferase	mphA	-	-	-	-	-	-	-	-	-	-	-	APH
IOLKFBCL_00764	216816.GS08_07160	1.13e-44	144.0	2AS45@1|root,31HGW@2|Bacteria,2HZSD@201174|Actinobacteria,4D1H9@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3107)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3107
IOLKFBCL_00765	216816.GS08_07165	1.8e-215	594.0	COG0613@1|root,COG0613@2|Bacteria,2GNAP@201174|Actinobacteria,4CYQ5@85004|Bifidobacteriales	201174|Actinobacteria	S	DNA polymerase alpha chain like domain	PPA1328	-	3.1.3.97,3.1.4.57	ko:K07053,ko:K20859	ko00440,map00440	-	R00188,R10972,R10973,R11188	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	PHP
IOLKFBCL_00766	216816.GS08_07170	1.8e-164	461.0	COG4243@1|root,COG4243@2|Bacteria,2GMVK@201174|Actinobacteria,4CZN1@85004|Bifidobacteriales	201174|Actinobacteria	S	Vitamin K epoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	VKOR
IOLKFBCL_00767	216816.GS08_07175	1.93e-210	582.0	COG0253@1|root,COG0253@2|Bacteria,2GKUD@201174|Actinobacteria,4CYQP@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
IOLKFBCL_00768	216816.GS08_07180	1.34e-189	526.0	COG0796@1|root,COG0796@2|Bacteria,2GN4I@201174|Actinobacteria,4CZ54@85004|Bifidobacteriales	201174|Actinobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	GO:0000270,GO:0003674,GO:0003824,GO:0004857,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008657,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010911,GO:0016020,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0030234,GO:0032780,GO:0034645,GO:0036361,GO:0042030,GO:0042546,GO:0043086,GO:0043170,GO:0043462,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0047661,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0072586,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:2000371,GO:2000372	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
IOLKFBCL_00769	216816.GS08_07185	4.89e-201	556.0	COG4667@1|root,COG4667@2|Bacteria,2I8R7@201174|Actinobacteria,4CZUH@85004|Bifidobacteriales	201174|Actinobacteria	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
IOLKFBCL_00770	216816.GS08_07190	5.52e-171	483.0	COG0330@1|root,COG0330@2|Bacteria,2GJ1U@201174|Actinobacteria,4CYTU@85004|Bifidobacteriales	201174|Actinobacteria	O	prohibitin homologues	hflK	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Band_7
IOLKFBCL_00771	216816.GS08_07195	2.37e-143	405.0	COG0765@1|root,COG0765@2|Bacteria,2GJJ9@201174|Actinobacteria,4CZIX@85004|Bifidobacteriales	201174|Actinobacteria	E	Binding-protein-dependent transport system inner membrane component	tcyA/tcyB	-	-	ko:K02029,ko:K02424,ko:K10009	ko02010,map02010	M00234,M00236	-	-	ko00000,ko00001,ko00002,ko02000,ko02035	3.A.1.3,3.A.1.3.10,3.A.1.3.14	-	-	BPD_transp_1,SBP_bac_3
IOLKFBCL_00772	216816.GS08_07200	4.62e-184	513.0	COG0834@1|root,COG0834@2|Bacteria,2GJQW@201174|Actinobacteria,4D0FX@85004|Bifidobacteriales	201174|Actinobacteria	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	ko:K02424	ko02010,map02010	M00234	-	-	ko00000,ko00001,ko00002,ko02000,ko02035	3.A.1.3.10,3.A.1.3.14	-	-	SBP_bac_3
IOLKFBCL_00773	216816.GS08_07205	1.19e-177	495.0	COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria,4D0CN@85004|Bifidobacteriales	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	ehuA	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
IOLKFBCL_00774	216816.GS08_07210	4.77e-306	835.0	COG2873@1|root,COG2873@2|Bacteria,2I8JG@201174|Actinobacteria,4CZ6W@85004|Bifidobacteriales	201174|Actinobacteria	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
IOLKFBCL_00775	216816.GS08_07215	3.12e-293	800.0	COG1473@1|root,COG1473@2|Bacteria,2GK05@201174|Actinobacteria,4D053@85004|Bifidobacteriales	201174|Actinobacteria	S	Peptidase dimerisation domain	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
IOLKFBCL_00776	216816.GS08_07220	0.0	1162.0	COG0410@1|root,COG0411@1|root,COG0410@2|Bacteria,COG0411@2|Bacteria,2GKSQ@201174|Actinobacteria,4CZE0@85004|Bifidobacteriales	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
IOLKFBCL_00777	216816.GS08_07225	0.0	1110.0	COG0559@1|root,COG4177@1|root,COG0559@2|Bacteria,COG4177@2|Bacteria,2GJB3@201174|Actinobacteria,4D2SK@85004|Bifidobacteriales	201174|Actinobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
IOLKFBCL_00778	216816.GS08_07230	1.45e-280	766.0	COG0683@1|root,COG0683@2|Bacteria,2GM00@201174|Actinobacteria,4CZYU@85004|Bifidobacteriales	201174|Actinobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
IOLKFBCL_00779	216816.GS08_07235	5.85e-253	693.0	COG0407@1|root,COG0407@2|Bacteria,2IBXM@201174|Actinobacteria,4D067@85004|Bifidobacteriales	201174|Actinobacteria	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
IOLKFBCL_00780	216816.GS08_07240	4.46e-185	515.0	COG0345@1|root,COG0345@2|Bacteria,2GJ7D@201174|Actinobacteria,4CZK0@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
IOLKFBCL_00781	216816.GS08_07245	2.84e-199	550.0	COG0346@1|root,COG0346@2|Bacteria,2IH7I@201174|Actinobacteria,4D0TJ@85004|Bifidobacteriales	201174|Actinobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_3
IOLKFBCL_00782	216816.GS08_07250	2.28e-57	177.0	COG0695@1|root,COG0695@2|Bacteria,2HZQB@201174|Actinobacteria,4D18H@85004|Bifidobacteriales	201174|Actinobacteria	O	Glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
IOLKFBCL_00783	216816.GS08_07255	9.3e-291	794.0	COG0626@1|root,COG0626@2|Bacteria,2GJ5S@201174|Actinobacteria,4CZKK@85004|Bifidobacteriales	201174|Actinobacteria	E	Cys/Met metabolism PLP-dependent enzyme	metC1	-	4.4.1.8	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
IOLKFBCL_00784	566552.BIFCAT_01775	1.1e-165	469.0	COG0834@1|root,COG0834@2|Bacteria,2GJH8@201174|Actinobacteria,4CZAC@85004|Bifidobacteriales	201174|Actinobacteria	ET	Bacterial periplasmic substrate-binding proteins	glnH	-	-	ko:K02030,ko:K10039	ko02010,map02010	M00228,M00236	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
IOLKFBCL_00785	401473.BDP_0689	2.19e-144	412.0	COG1126@1|root,COG1126@2|Bacteria,2H1ZM@201174|Actinobacteria,4CZTK@85004|Bifidobacteriales	201174|Actinobacteria	E	ATP binding protein of ABC transporter for glutamate aspartate K02028	glnQ	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
IOLKFBCL_00786	518635.BIFANG_02430	1.31e-142	404.0	COG0765@1|root,COG0765@2|Bacteria,2GN44@201174|Actinobacteria,4CZG7@85004|Bifidobacteriales	201174|Actinobacteria	E	Binding-protein-dependent transport system inner membrane component	glnP	-	-	ko:K02029,ko:K10040	ko02010,map02010	M00228,M00236	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
IOLKFBCL_00787	566552.BIFCAT_01772	2.04e-125	360.0	COG0765@1|root,COG0765@2|Bacteria,2GM0I@201174|Actinobacteria,4CZ8E@85004|Bifidobacteriales	201174|Actinobacteria	E	Binding-protein-dependent transport system inner membrane component	glnP2	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
IOLKFBCL_00788	216816.GS08_07260	3.56e-152	427.0	COG0400@1|root,COG0400@2|Bacteria,2I5NR@201174|Actinobacteria,4CZJQ@85004|Bifidobacteriales	201174|Actinobacteria	S	Phospholipase/Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
IOLKFBCL_00789	216816.GS08_07265	0.0	1484.0	COG0480@1|root,COG0480@2|Bacteria,2GJ64@201174|Actinobacteria,4CZM5@85004|Bifidobacteriales	201174|Actinobacteria	J	Elongation factor G, domain IV	tetM	-	-	ko:K18220	-	-	-	-	br01600,ko00000,ko01504	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
IOLKFBCL_00790	216816.GS08_07270	3.16e-169	472.0	COG2176@1|root,COG2176@2|Bacteria,2I2FU@201174|Actinobacteria,4D10C@85004|Bifidobacteriales	201174|Actinobacteria	L	Exonuclease, DNA polymerase III, epsilon subunit family	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	BRCT,RNase_T
IOLKFBCL_00792	216816.GS08_07275	4.38e-134	380.0	COG0194@1|root,COG0194@2|Bacteria,2I2FT@201174|Actinobacteria,4CYUT@85004|Bifidobacteriales	201174|Actinobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
IOLKFBCL_00793	216816.GS08_07280	2.09e-214	592.0	COG0284@1|root,COG0284@2|Bacteria,2GKWK@201174|Actinobacteria,4D2UX@85004|Bifidobacteriales	201174|Actinobacteria	F	Essential for recycling GMP and indirectly, cGMP	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
IOLKFBCL_00794	216816.GS08_07285	0.0	2201.0	COG0458@1|root,COG0458@2|Bacteria,2GK5N@201174|Actinobacteria,4CZJ4@85004|Bifidobacteriales	201174|Actinobacteria	EF	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
IOLKFBCL_00795	216816.GS08_07290	1.05e-303	829.0	COG0505@1|root,COG0505@2|Bacteria,2GKFA@201174|Actinobacteria,4CYQ1@85004|Bifidobacteriales	201174|Actinobacteria	F	Belongs to the CarA family	carA	GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1383	CPSase_sm_chain,GATase
IOLKFBCL_00796	216816.GS08_07295	1.72e-122	350.0	COG0781@1|root,COG0781@2|Bacteria,2IM3D@201174|Actinobacteria,4D0WG@85004|Bifidobacteriales	201174|Actinobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	GO:0008150,GO:0040007	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
IOLKFBCL_00797	216816.GS08_07300	7.09e-136	384.0	COG0231@1|root,COG0231@2|Bacteria,2GJMS@201174|Actinobacteria,4CYY6@85004|Bifidobacteriales	201174|Actinobacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
IOLKFBCL_00798	216816.GS08_07305	1.52e-145	413.0	COG1136@1|root,COG1136@2|Bacteria,2I8QP@201174|Actinobacteria,4CZZG@85004|Bifidobacteriales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02068	-	M00211	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
IOLKFBCL_00799	216816.GS08_07310	4.66e-164	461.0	COG0390@1|root,COG0390@2|Bacteria,2GMHX@201174|Actinobacteria,4CYRQ@85004|Bifidobacteriales	201174|Actinobacteria	V	Uncharacterised protein family (UPF0014)	-	-	-	ko:K02069	-	M00211	-	-	ko00000,ko00002,ko02000	9.B.25.1	-	-	UPF0014
IOLKFBCL_00800	216816.GS08_07345	0.0	1122.0	COG3525@1|root,COG3525@2|Bacteria,2HZCI@201174|Actinobacteria,4CZS1@85004|Bifidobacteriales	201174|Actinobacteria	G	Glycosyl hydrolase family 20, domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_20,Glyco_hydro_20b
IOLKFBCL_00801	216816.GS08_07375	7.45e-257	705.0	COG0489@1|root,COG2151@1|root,COG0489@2|Bacteria,COG2151@2|Bacteria,2GJUZ@201174|Actinobacteria,4CZDC@85004|Bifidobacteriales	201174|Actinobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	GO:0008150,GO:0040007	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
IOLKFBCL_00802	216816.GS08_07380	0.0	1793.0	COG0272@1|root,COG0272@2|Bacteria,2GJUY@201174|Actinobacteria,4CZBC@85004|Bifidobacteriales	201174|Actinobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016874,GO:0016886,GO:0030312,GO:0033554,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2
IOLKFBCL_00803	216816.GS08_07385	0.0	2275.0	COG0457@1|root,COG0457@2|Bacteria,2GWSR@201174|Actinobacteria,4CZ33@85004|Bifidobacteriales	201174|Actinobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
IOLKFBCL_00804	216816.GS08_07390	0.0	1411.0	COG1807@1|root,COG1807@2|Bacteria,2GNXR@201174|Actinobacteria,4CZXK@85004|Bifidobacteriales	201174|Actinobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00805	216816.GS08_07395	1.2e-178	499.0	COG1122@1|root,COG1122@2|Bacteria,2I9PF@201174|Actinobacteria,4D04S@85004|Bifidobacteriales	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K16784	ko02010,map02010	M00581	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25.1	-	-	ABC_tran
IOLKFBCL_00806	216816.GS08_07400	1.25e-284	780.0	COG0436@1|root,COG0436@2|Bacteria,2GNMB@201174|Actinobacteria,4CZ48@85004|Bifidobacteriales	201174|Actinobacteria	E	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
IOLKFBCL_00807	216816.GS08_07405	1.56e-179	500.0	COG1940@1|root,COG1940@2|Bacteria,2GJA0@201174|Actinobacteria,4CYR1@85004|Bifidobacteriales	201174|Actinobacteria	GK	ROK family	ppgK	-	2.7.1.2,2.7.1.63	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786,R02187,R02189	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
IOLKFBCL_00808	216816.GS08_07410	5.22e-257	703.0	COG1216@1|root,COG1216@2|Bacteria,2GMQQ@201174|Actinobacteria,4CZRJ@85004|Bifidobacteriales	201174|Actinobacteria	S	Glycosyltransferase, group 2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
IOLKFBCL_00809	216816.GS08_07415	2.87e-138	392.0	COG3601@1|root,COG3601@2|Bacteria,2IAX0@201174|Actinobacteria,4CZQD@85004|Bifidobacteriales	201174|Actinobacteria	U	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins	-	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
IOLKFBCL_00810	216816.GS08_07420	0.0	1425.0	COG0619@1|root,COG1129@1|root,COG0619@2|Bacteria,COG1129@2|Bacteria,2I2G4@201174|Actinobacteria,4CZJE@85004|Bifidobacteriales	201174|Actinobacteria	GP	ABC transporter, ATP-binding protein	-	-	-	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran,CbiQ
IOLKFBCL_00811	216816.GS08_07425	7.75e-62	190.0	COG1534@1|root,COG1534@2|Bacteria,2IKSS@201174|Actinobacteria,4D10K@85004|Bifidobacteriales	201174|Actinobacteria	J	CRS1_YhbY	-	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
IOLKFBCL_00812	216816.GS08_07430	8.24e-71	214.0	COG1950@1|root,COG1950@2|Bacteria,2HZND@201174|Actinobacteria,4D117@85004|Bifidobacteriales	201174|Actinobacteria	S	Mycobacterial 4 TMS phage holin, superfamily IV	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
IOLKFBCL_00813	216816.GS08_07435	6.5e-106	311.0	COG2314@1|root,COG2314@2|Bacteria,2IQB3@201174|Actinobacteria,4D11Z@85004|Bifidobacteriales	201174|Actinobacteria	J	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	TM2
IOLKFBCL_00814	216816.GS08_07440	9.11e-236	648.0	COG0111@1|root,COG0111@2|Bacteria,2GP09@201174|Actinobacteria,4CZUN@85004|Bifidobacteriales	201174|Actinobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
IOLKFBCL_00815	216816.GS08_07445	8.57e-316	864.0	COG0477@1|root,COG2814@2|Bacteria,2GIZX@201174|Actinobacteria,4CZ0R@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
IOLKFBCL_00816	216816.GS08_07485	1.92e-314	858.0	COG2256@1|root,COG2256@2|Bacteria,2GKDP@201174|Actinobacteria,4CZ2K@85004|Bifidobacteriales	201174|Actinobacteria	L	Recombination factor protein RarA	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
IOLKFBCL_00817	216816.GS08_07490	0.0	1694.0	COG4581@1|root,COG4581@2|Bacteria,2GJSV@201174|Actinobacteria,4CZVX@85004|Bifidobacteriales	201174|Actinobacteria	L	DEAD DEAH box helicase	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,DUF3516,Helicase_C
IOLKFBCL_00818	216816.GS08_07495	7.07e-250	686.0	COG2326@1|root,COG2326@2|Bacteria,2GKRN@201174|Actinobacteria,4CZZU@85004|Bifidobacteriales	201174|Actinobacteria	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
IOLKFBCL_00819	216816.GS08_07505	4.97e-31	122.0	COG0737@1|root,COG3204@1|root,COG0737@2|Bacteria,COG3204@2|Bacteria,2GKC3@201174|Actinobacteria,4D03Y@85004|Bifidobacteriales	201174|Actinobacteria	F	5'-nucleotidase, C-terminal domain	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Exo_endo_phos,LTD,Metallophos
IOLKFBCL_00820	216816.GS08_07510	0.0	975.0	COG0671@1|root,COG0671@2|Bacteria,2I4ZG@201174|Actinobacteria,4CZ80@85004|Bifidobacteriales	201174|Actinobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
IOLKFBCL_00821	216816.GS08_07515	3.82e-238	657.0	COG0765@1|root,COG0765@2|Bacteria,2GNBH@201174|Actinobacteria,4CZB4@85004|Bifidobacteriales	201174|Actinobacteria	E	Binding-protein-dependent transport system inner membrane component	gluD	-	-	ko:K10007	ko02010,map02010	M00233	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.9	-	-	BPD_transp_1
IOLKFBCL_00822	326426.Bbr_1344	3.05e-137	390.0	COG0765@1|root,COG0765@2|Bacteria,2GNUR@201174|Actinobacteria,4CZ5M@85004|Bifidobacteriales	201174|Actinobacteria	E	Binding-protein-dependent transport system inner membrane component	gluC	-	-	ko:K10006	ko02010,map02010	M00233	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.9	-	-	BPD_transp_1
IOLKFBCL_00823	216816.GS08_07525	1.98e-194	540.0	COG0834@1|root,COG0834@2|Bacteria,2GJH8@201174|Actinobacteria,4CZA4@85004|Bifidobacteriales	201174|Actinobacteria	ET	Belongs to the bacterial solute-binding protein 3 family	gluB	-	-	ko:K10005	ko02010,map02010	M00233	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.9	-	-	SBP_bac_3
IOLKFBCL_00824	326426.Bbr_1346	7.84e-181	505.0	COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria,4CYXE@85004|Bifidobacteriales	201174|Actinobacteria	E	ATP-binding protein of ABC transporter for glutamate K02028	gluA	-	-	ko:K10008	ko02010,map02010	M00233	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3.9	-	-	ABC_tran
IOLKFBCL_00825	216816.GS08_07540	3.55e-232	638.0	COG2852@1|root,COG2852@2|Bacteria,2GN40@201174|Actinobacteria,4CZJT@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
IOLKFBCL_00826	216816.GS08_07545	0.0	1203.0	COG0173@1|root,COG0173@2|Bacteria,2GJHU@201174|Actinobacteria,4CYWQ@85004|Bifidobacteriales	201174|Actinobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
IOLKFBCL_00827	216816.GS08_07550	0.0	901.0	COG0124@1|root,COG0124@2|Bacteria,2GIYJ@201174|Actinobacteria,4CYR9@85004|Bifidobacteriales	201174|Actinobacteria	J	Histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
IOLKFBCL_00828	216816.GS08_07555	0.0	869.0	COG3266@1|root,COG3266@2|Bacteria,2I2EC@201174|Actinobacteria,4CYYM@85004|Bifidobacteriales	201174|Actinobacteria	S	Domain of Unknown Function (DUF349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF349
IOLKFBCL_00829	216816.GS08_07560	0.0	1075.0	COG0737@1|root,COG0737@2|Bacteria,2GKC3@201174|Actinobacteria,4D0CZ@85004|Bifidobacteriales	201174|Actinobacteria	F	5'-nucleotidase, C-terminal domain	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
IOLKFBCL_00830	216816.GS08_07565	3.69e-181	504.0	COG1402@1|root,COG1402@2|Bacteria,2HCRK@201174|Actinobacteria,4CZW9@85004|Bifidobacteriales	201174|Actinobacteria	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
IOLKFBCL_00831	216816.GS08_07570	1.82e-316	863.0	COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria,4CYY8@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Sugar (and other) transporter	proP	-	-	ko:K03762	-	-	-	-	ko00000,ko02000	2.A.1.6.4	-	-	MFS_1,Sugar_tr
IOLKFBCL_00832	216816.GS08_07580	0.0	954.0	COG2508@1|root,COG2508@2|Bacteria,2HPPC@201174|Actinobacteria,4D0FM@85004|Bifidobacteriales	201174|Actinobacteria	QT	Purine catabolism regulatory protein-like family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30,PucR
IOLKFBCL_00833	216816.GS08_07585	0.0	880.0	COG0402@1|root,COG0402@2|Bacteria,2GKKM@201174|Actinobacteria,4D07T@85004|Bifidobacteriales	201174|Actinobacteria	F	Amidohydrolase family	codA	-	3.5.4.1,3.5.4.21	ko:K01485,ko:K03365	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922	RC00074,RC00514,RC00809	ko00000,ko00001,ko01000	-	-	-	Amidohydro_3
IOLKFBCL_00834	216816.GS08_07590	0.0	1586.0	COG0542@1|root,COG0542@2|Bacteria,2GJ77@201174|Actinobacteria,4CZCH@85004|Bifidobacteriales	201174|Actinobacteria	O	ATPase family associated with various cellular activities (AAA)	clpC	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
IOLKFBCL_00835	216816.GS08_07595	1.67e-223	617.0	COG0589@1|root,COG0589@2|Bacteria,2IA7S@201174|Actinobacteria,4CZZ0@85004|Bifidobacteriales	201174|Actinobacteria	T	Belongs to the universal stress protein A family	uspA	-	-	-	-	-	-	-	-	-	-	-	Usp
IOLKFBCL_00836	216816.GS08_07630	3.16e-247	683.0	28NWB@1|root,2ZBU7@2|Bacteria,2GJ74@201174|Actinobacteria,4CYW9@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3027)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3027
IOLKFBCL_00837	216816.GS08_07635	1.01e-86	255.0	COG1278@1|root,COG1278@2|Bacteria,2IKXN@201174|Actinobacteria,4D0V4@85004|Bifidobacteriales	201174|Actinobacteria	K	'Cold-shock' DNA-binding domain	cspB	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
IOLKFBCL_00838	216816.GS08_07640	0.0	1247.0	COG2770@1|root,COG5002@1|root,COG2770@2|Bacteria,COG5002@2|Bacteria,2I2DU@201174|Actinobacteria,4CZNF@85004|Bifidobacteriales	201174|Actinobacteria	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	phoR	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
IOLKFBCL_00839	216816.GS08_07645	2.26e-170	476.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4CYPS@85004|Bifidobacteriales	201174|Actinobacteria	KT	Response regulator receiver domain protein	phoP	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
IOLKFBCL_00840	216816.GS08_07650	5.32e-113	329.0	2B59T@1|root,31Y3Y@2|Bacteria,2HZNR@201174|Actinobacteria,4D12Q@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TPM_phosphatase
IOLKFBCL_00841	216816.GS08_07655	2.78e-55	173.0	COG4842@1|root,COG4842@2|Bacteria,2GQI8@201174|Actinobacteria,4D17K@85004|Bifidobacteriales	201174|Actinobacteria	S	Proteins of 100 residues with WXG	-	-	-	-	-	-	-	-	-	-	-	-	WXG100
IOLKFBCL_00842	216816.GS08_07660	0.0	1005.0	COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria,4CZJK@85004|Bifidobacteriales	201174|Actinobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016020,GO:0016465,GO:0022610,GO:0030112,GO:0030312,GO:0030313,GO:0031975,GO:0032991,GO:0036293,GO:0040007,GO:0042026,GO:0042603,GO:0043388,GO:0044093,GO:0044183,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051082,GO:0051098,GO:0051099,GO:0051101,GO:0051704,GO:0061077,GO:0065007,GO:0065009,GO:0070482,GO:0071944,GO:0101031,GO:1990220,GO:2000677,GO:2000679	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
IOLKFBCL_00843	216816.GS08_07665	2.18e-51	162.0	COG1278@1|root,COG1278@2|Bacteria,2GQRU@201174|Actinobacteria,4D1FB@85004|Bifidobacteriales	201174|Actinobacteria	K	'Cold-shock' DNA-binding domain	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
IOLKFBCL_00844	216816.GS08_07670	8.52e-95	283.0	2DP6P@1|root,330SA@2|Bacteria,2GQYA@201174|Actinobacteria,4CZYT@85004|Bifidobacteriales	201174|Actinobacteria	S	LytR cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C
IOLKFBCL_00845	216816.GS08_07675	1.02e-171	478.0	COG0692@1|root,COG0692@2|Bacteria,2GJ9Z@201174|Actinobacteria,4CZ3Y@85004|Bifidobacteriales	201174|Actinobacteria	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
IOLKFBCL_00846	216816.GS08_07680	6.79e-249	684.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4CZ2I@85004|Bifidobacteriales	201174|Actinobacteria	S	ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
IOLKFBCL_00847	216816.GS08_07685	1.04e-219	607.0	COG1721@1|root,COG1721@2|Bacteria,2GKSJ@201174|Actinobacteria,4CYYD@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
IOLKFBCL_00848	216816.GS08_07690	3.68e-117	336.0	2AUTC@1|root,31KGE@2|Bacteria,2IKRN@201174|Actinobacteria,4D134@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00849	216816.GS08_07695	1.51e-237	655.0	COG2304@1|root,COG2304@2|Bacteria,2I9VM@201174|Actinobacteria,4CZ00@85004|Bifidobacteriales	201174|Actinobacteria	S	von Willebrand factor (vWF) type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
IOLKFBCL_00850	216816.GS08_07700	7.86e-224	619.0	COG2304@1|root,COG2304@2|Bacteria,2GJMP@201174|Actinobacteria,4CZ8P@85004|Bifidobacteriales	201174|Actinobacteria	S	von Willebrand factor (vWF) type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
IOLKFBCL_00851	216816.GS08_07705	3.86e-90	268.0	2BG6D@1|root,32A37@2|Bacteria,2IR67@201174|Actinobacteria,4D18W@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00852	216816.GS08_07710	1.33e-69	210.0	2B109@1|root,31TDG@2|Bacteria,2GS74@201174|Actinobacteria,4D1MD@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00853	216816.GS08_07715	0.0	1009.0	COG1075@1|root,COG1075@2|Bacteria,2IHFB@201174|Actinobacteria,4CZ17@85004|Bifidobacteriales	201174|Actinobacteria	S	PGAP1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Abhydrolase_8,PGAP1
IOLKFBCL_00854	216816.GS08_07730	0.0	964.0	COG0015@1|root,COG0015@2|Bacteria,2GM71@201174|Actinobacteria,4CYV6@85004|Bifidobacteriales	201174|Actinobacteria	F	Adenylosuccinate lyase C-terminal	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ASL_C,Lyase_1
IOLKFBCL_00855	216816.GS08_07735	0.0	1506.0	COG0392@1|root,COG0392@2|Bacteria,2GMAV@201174|Actinobacteria,4CYRT@85004|Bifidobacteriales	201174|Actinobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
IOLKFBCL_00856	216816.GS08_07740	3.31e-57	177.0	COG0776@1|root,COG0776@2|Bacteria,2IKQR@201174|Actinobacteria,4D11V@85004|Bifidobacteriales	201174|Actinobacteria	L	Belongs to the bacterial histone-like protein family	hup	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
IOLKFBCL_00859	1437610.BREU_0807	2.38e-77	233.0	28PY9@1|root,2ZCI0@2|Bacteria,2INBV@201174|Actinobacteria,4D13Q@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00860	78344.BIGA_0003	5.58e-317	889.0	COG1484@1|root,COG4584@1|root,COG1484@2|Bacteria,COG4584@2|Bacteria,2IBDV@201174|Actinobacteria,4CZS6@85004|Bifidobacteriales	201174|Actinobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_7,IstB_IS21,rve
IOLKFBCL_00861	547043.BIFPSEUDO_03278	2.33e-49	163.0	COG2801@1|root,COG2801@2|Bacteria,2GKDY@201174|Actinobacteria,4CZQK@85004|Bifidobacteriales	201174|Actinobacteria	L	Integrase core domain	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_Tnp_1,rve,rve_3
IOLKFBCL_00862	216816.GS08_10200	7.6e-53	167.0	COG2963@1|root,COG2963@2|Bacteria,2IRD7@201174|Actinobacteria,4D16D@85004|Bifidobacteriales	201174|Actinobacteria	L	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
IOLKFBCL_00863	762211.BSTEL_1538	2.76e-68	209.0	COG0537@1|root,COG0537@2|Bacteria	2|Bacteria	FG	bis(5'-adenosyl)-triphosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	HIT
IOLKFBCL_00864	762211.BSTEL_1537	3.48e-218	616.0	COG1904@1|root,COG1904@2|Bacteria,2I8PE@201174|Actinobacteria,4D085@85004|Bifidobacteriales	201174|Actinobacteria	G	Glucuronate isomerase	uxaC	-	5.3.1.12	ko:K01812	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	UxaC
IOLKFBCL_00865	762211.BSTEL_1536	5.93e-242	676.0	COG0246@1|root,COG0246@2|Bacteria,2GJ4F@201174|Actinobacteria,4D0F8@85004|Bifidobacteriales	201174|Actinobacteria	G	Mannitol dehydrogenase C-terminal domain	mtlD	-	1.1.1.57,1.1.1.58	ko:K00040,ko:K00041	ko00040,ko01100,map00040,map01100	M00061,M00631	R02454,R02555	RC00085	ko00000,ko00001,ko00002,ko01000	-	-	-	Mannitol_dh,Mannitol_dh_C
IOLKFBCL_00866	762211.BSTEL_1535	1.82e-295	806.0	COG4948@1|root,COG4948@2|Bacteria,2GT81@201174|Actinobacteria	201174|Actinobacteria	M	mandelate racemase muconate lactonizing	-	-	4.2.1.8	ko:K08323	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
IOLKFBCL_00867	1437610.BREU_0418	2.21e-286	797.0	COG0362@1|root,COG0362@2|Bacteria,2GJ2J@201174|Actinobacteria,4CZFG@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
IOLKFBCL_00868	762211.BSTEL_1539	4.05e-89	278.0	COG1609@1|root,COG1609@2|Bacteria,2GMUU@201174|Actinobacteria,4D0SY@85004|Bifidobacteriales	201174|Actinobacteria	K	Periplasmic binding proteins and sugar binding domain of LacI family	-	-	-	ko:K02529,ko:K05499	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
IOLKFBCL_00869	1122933.JNIY01000003_gene198	6.63e-68	223.0	COG1609@1|root,COG1609@2|Bacteria,2GMUU@201174|Actinobacteria,4F1RR@85016|Cellulomonadaceae	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529,ko:K05499	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
IOLKFBCL_00870	158787.BSCA_0378	2.82e-122	375.0	COG2211@1|root,COG2211@2|Bacteria,2IAMT@201174|Actinobacteria,4CZNI@85004|Bifidobacteriales	201174|Actinobacteria	G	MFS/sugar transport protein	-	-	-	ko:K16210	-	-	-	-	ko00000,ko02000	2.A.2.5	-	-	MFS_2,Peripla_BP_3
IOLKFBCL_00871	216816.GS08_00715	0.0	925.0	COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,2GKW1@201174|Actinobacteria,4D05P@85004|Bifidobacteriales	201174|Actinobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,HTH_28,rve,rve_2
IOLKFBCL_00872	1158606.I579_01182	1.12e-182	526.0	COG2211@1|root,COG2211@2|Bacteria,1U037@1239|Firmicutes,4HBZK@91061|Bacilli,4B4RK@81852|Enterococcaceae	91061|Bacilli	G	MFS/sugar transport protein	uxuT	-	-	ko:K03292,ko:K16210	-	-	-	-	ko00000,ko02000	2.A.2,2.A.2.5	-	-	MFS_2
IOLKFBCL_00873	78346.BRUM_0813	7.51e-16	73.6	COG2963@1|root,COG2963@2|Bacteria,2IF4K@201174|Actinobacteria,4D0JP@85004|Bifidobacteriales	201174|Actinobacteria	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_28
IOLKFBCL_00874	1437610.BREU_1897	7.83e-83	258.0	COG2801@1|root,COG3415@1|root,COG2801@2|Bacteria,COG3415@2|Bacteria,2GKW1@201174|Actinobacteria,4D05P@85004|Bifidobacteriales	201174|Actinobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve,rve_2
IOLKFBCL_00875	78344.BIGA_1749	2.28e-58	192.0	COG2963@1|root,COG3328@1|root,COG2963@2|Bacteria,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria,4D023@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
IOLKFBCL_00876	326426.Bbr_0157	8.14e-201	555.0	COG1524@1|root,COG1524@2|Bacteria,2HQI2@201174|Actinobacteria	201174|Actinobacteria	I	type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2,Phosphodiest
IOLKFBCL_00877	326426.Bbr_0156	4.28e-254	698.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4CZPE@85004|Bifidobacteriales	201174|Actinobacteria	E	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	-	ko:K02052	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	ABC_tran,TOBE_2
IOLKFBCL_00878	326426.Bbr_0155	9.99e-198	550.0	COG1177@1|root,COG1177@2|Bacteria,2GM0E@201174|Actinobacteria,4CZ2N@85004|Bifidobacteriales	201174|Actinobacteria	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02053	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
IOLKFBCL_00879	326426.Bbr_0154	4.24e-195	543.0	COG4132@1|root,COG4132@2|Bacteria,2GNDF@201174|Actinobacteria,4CZHE@85004|Bifidobacteriales	201174|Actinobacteria	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02054	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
IOLKFBCL_00880	326426.Bbr_0153	1.28e-256	705.0	COG1840@1|root,COG1840@2|Bacteria,2HG0J@201174|Actinobacteria,4D2IZ@85004|Bifidobacteriales	201174|Actinobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02055	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	SBP_bac_6
IOLKFBCL_00881	216816.GS08_07870	0.0	2221.0	COG0060@1|root,COG0060@2|Bacteria,2GK9M@201174|Actinobacteria,4CYT7@85004|Bifidobacteriales	201174|Actinobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
IOLKFBCL_00882	216816.GS08_07875	9.15e-308	837.0	COG1168@1|root,COG1168@2|Bacteria,2GJFQ@201174|Actinobacteria,4CZFH@85004|Bifidobacteriales	201174|Actinobacteria	E	Aminotransferase, class I II	patB	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
IOLKFBCL_00883	1437603.BMON_1669	8.6e-206	572.0	COG0329@1|root,COG0329@2|Bacteria,2GJDB@201174|Actinobacteria,4D04B@85004|Bifidobacteriales	201174|Actinobacteria	EM	Dihydrodipicolinate synthetase family	nanA	-	4.1.3.3,4.3.3.7	ko:K01639,ko:K01714	ko00261,ko00300,ko00520,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00520,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R01811,R10147	RC00159,RC00600,RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
IOLKFBCL_00884	1437603.BMON_1670	5.48e-181	506.0	COG4608@1|root,COG4608@2|Bacteria,2H4BW@201174|Actinobacteria,4CYR3@85004|Bifidobacteriales	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	oppF	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
IOLKFBCL_00885	1437603.BMON_1671	0.0	1236.0	COG0444@1|root,COG1173@1|root,COG0444@2|Bacteria,COG1173@2|Bacteria,2GIXV@201174|Actinobacteria,4D0C4@85004|Bifidobacteriales	201174|Actinobacteria	EP	Oligopeptide/dipeptide transporter, C-terminal region	oppCD2	-	-	ko:K02031,ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,BPD_transp_1,OppC_N,oligo_HPY
IOLKFBCL_00886	1437603.BMON_1672	9.16e-215	594.0	COG0601@1|root,COG0601@2|Bacteria,2GK0Z@201174|Actinobacteria,4D2RG@85004|Bifidobacteriales	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	oppB6	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
IOLKFBCL_00887	1437603.BMON_1673	0.0	942.0	COG0747@1|root,COG0747@2|Bacteria,2GK4Y@201174|Actinobacteria,4CYSK@85004|Bifidobacteriales	201174|Actinobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	oppA7	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5,TAT_signal
IOLKFBCL_00888	1437603.BMON_1674	0.0	1187.0	COG4409@1|root,COG4409@2|Bacteria,2I0CJ@201174|Actinobacteria,4D02H@85004|Bifidobacteriales	201174|Actinobacteria	G	BNR repeat-like domain	neu	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Laminin_G_3
IOLKFBCL_00889	1437603.BMON_1675	1.59e-147	417.0	COG3010@1|root,COG3010@2|Bacteria,2GTWV@201174|Actinobacteria,4CZK9@85004|Bifidobacteriales	201174|Actinobacteria	G	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)	nanE	-	5.1.3.9	ko:K01788	ko00520,map00520	-	R02087	RC00290	ko00000,ko00001,ko01000	-	-	-	NanE
IOLKFBCL_00890	1437603.BMON_1676	4.56e-153	438.0	COG1940@1|root,COG1940@2|Bacteria,2GJCQ@201174|Actinobacteria,4D0EX@85004|Bifidobacteriales	201174|Actinobacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
IOLKFBCL_00891	1437603.BMON_1677	4.06e-181	508.0	COG0648@1|root,COG0648@2|Bacteria,2I8IU@201174|Actinobacteria,4D0HP@85004|Bifidobacteriales	201174|Actinobacteria	L	Domain of unknown function (DUF4862)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4862
IOLKFBCL_00892	1437603.BMON_1678	9.68e-138	394.0	COG2186@1|root,COG2186@2|Bacteria,2GJ82@201174|Actinobacteria,4D0K7@85004|Bifidobacteriales	201174|Actinobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
IOLKFBCL_00893	216816.GS08_07885	3.08e-222	615.0	COG1609@1|root,COG1609@2|Bacteria,2H5ZG@201174|Actinobacteria,4CZ8A@85004|Bifidobacteriales	201174|Actinobacteria	K	Transcriptional regulator, LacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
IOLKFBCL_00894	158787.BSCA_0810	7.25e-206	576.0	COG0524@1|root,COG0524@2|Bacteria,2I04R@201174|Actinobacteria,4CZIB@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
IOLKFBCL_00895	1437600.JDUI01000011_gene698	1.73e-16	77.4	COG1957@1|root,COG1957@2|Bacteria,2GP6N@201174|Actinobacteria,4CZ0Y@85004|Bifidobacteriales	201174|Actinobacteria	F	Inosine-uridine preferring nucleoside hydrolase	iunH2	-	3.2.2.1	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
IOLKFBCL_00896	547043.BIFPSEUDO_02355	5.61e-240	671.0	COG0477@1|root,COG2814@2|Bacteria,2H8UD@201174|Actinobacteria,4CZ16@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
IOLKFBCL_00897	547043.BIFPSEUDO_02356	7.79e-211	584.0	COG1957@1|root,COG1957@2|Bacteria,2GP6N@201174|Actinobacteria,4CZIN@85004|Bifidobacteriales	201174|Actinobacteria	F	Inosine-uridine preferring nucleoside hydrolase	rihB	-	3.2.2.1,3.2.2.8	ko:K01239,ko:K01250,ko:K10213	ko00230,ko00240,ko00760,ko01100,map00230,map00240,map00760,map01100	-	R01245,R01273,R01677,R01770,R02137,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
IOLKFBCL_00898	216816.GS08_07920	3.06e-173	491.0	COG1609@1|root,COG1609@2|Bacteria,2GNVD@201174|Actinobacteria,4CZNG@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	rbsR	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
IOLKFBCL_00899	216816.GS08_07925	0.0	1279.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4CZPJ@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
IOLKFBCL_00900	216816.GS08_07930	0.0	1138.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4CZMX@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter, ATP-binding protein	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
IOLKFBCL_00901	216816.GS08_07935	0.0	1377.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,2I2FR@201174|Actinobacteria,4D09B@85004|Bifidobacteriales	201174|Actinobacteria	T	Putative diguanylate phosphodiesterase	-	-	3.1.4.52	ko:K14051	ko02024,ko02026,map02024,map02026	-	-	-	ko00000,ko00001,ko01000	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4
IOLKFBCL_00902	326426.Bbr_0048	1.54e-144	409.0	COG1285@1|root,COG1285@2|Bacteria,2HZFV@201174|Actinobacteria,4D0AX@85004|Bifidobacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
IOLKFBCL_00903	216816.GS08_07945	3.07e-200	554.0	COG5036@1|root,COG5036@2|Bacteria,2HZIY@201174|Actinobacteria,4D0MA@85004|Bifidobacteriales	201174|Actinobacteria	P	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
IOLKFBCL_00904	216816.GS08_07950	0.0	1136.0	COG5337@1|root,COG5337@2|Bacteria,2ID5Z@201174|Actinobacteria,4D02F@85004|Bifidobacteriales	201174|Actinobacteria	M	CotH kinase protein	-	-	-	ko:K06330	-	-	-	-	ko00000	-	-	-	CotH
IOLKFBCL_00905	547043.BIFPSEUDO_02522	0.0	917.0	COG4267@1|root,COG4267@2|Bacteria,2IE76@201174|Actinobacteria,4CZ7D@85004|Bifidobacteriales	201174|Actinobacteria	S	Putative exopolysaccharide Exporter (EPS-E)	-	-	-	ko:K21012	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	PelG
IOLKFBCL_00906	326426.Bbr_0044	0.0	962.0	COG0438@1|root,COG0438@2|Bacteria,2GKEA@201174|Actinobacteria,4CZ5G@85004|Bifidobacteriales	201174|Actinobacteria	M	Domain of unknown function (DUF3492)	-	-	-	ko:K21011	ko02025,map02025	-	-	-	ko00000,ko00001,ko01003	-	GT4	-	DUF3492,Glyco_trans_1_4,Glycos_transf_1
IOLKFBCL_00907	216816.GS08_07965	0.0	1201.0	COG4878@1|root,COG4878@2|Bacteria,2IERA@201174|Actinobacteria,4D00K@85004|Bifidobacteriales	201174|Actinobacteria	S	Uncharacterised protein conserved in bacteria (DUF2194)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2194
IOLKFBCL_00908	216816.GS08_07970	9.11e-208	575.0	28H6W@1|root,2Z7J7@2|Bacteria,2ICGP@201174|Actinobacteria,4CZUA@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00909	326426.Bbr_0040	0.0	1360.0	COG0451@1|root,COG0451@2|Bacteria,2ICHN@201174|Actinobacteria,4CYZ7@85004|Bifidobacteriales	201174|Actinobacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
IOLKFBCL_00911	158787.BSCA_0785	0.0	1309.0	COG1472@1|root,COG1472@2|Bacteria,2GJ5H@201174|Actinobacteria,4CZ2P@85004|Bifidobacteriales	201174|Actinobacteria	G	Glycosyl hydrolase family 3 N-terminal domain protein	bglB	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
IOLKFBCL_00912	1437610.BREU_0902	8.03e-110	319.0	COG1309@1|root,COG1309@2|Bacteria,2I8DN@201174|Actinobacteria,4CZXN@85004|Bifidobacteriales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
IOLKFBCL_00913	401473.BDP_0967	1.46e-50	168.0	2B8XW@1|root,3228D@2|Bacteria,2H6J9@201174|Actinobacteria,4D2B4@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00914	216816.GS08_07990	1.5e-296	808.0	COG2730@1|root,COG2730@2|Bacteria,2I8WH@201174|Actinobacteria,4CZV7@85004|Bifidobacteriales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4,3.2.1.58	ko:K01179,ko:K01210	ko00500,ko01100,map00500,map01100	-	R00308,R03115,R06200,R11307,R11308	RC00467	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
IOLKFBCL_00915	216816.GS08_07995	2.55e-91	267.0	COG1669@1|root,COG1669@2|Bacteria,2IJSQ@201174|Actinobacteria,4D0XU@85004|Bifidobacteriales	201174|Actinobacteria	S	Nucleotidyltransferase substrate binding protein like	-	-	-	-	-	-	-	-	-	-	-	-	NTase_sub_bind
IOLKFBCL_00916	216816.GS08_08000	2.9e-61	188.0	COG1669@1|root,COG1669@2|Bacteria,2IMP4@201174|Actinobacteria,4D145@85004|Bifidobacteriales	201174|Actinobacteria	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
IOLKFBCL_00917	216816.GS08_08005	2.14e-76	251.0	COG1472@1|root,COG1472@2|Bacteria,2GJ5H@201174|Actinobacteria,4CZT6@85004|Bifidobacteriales	201174|Actinobacteria	G	Fibronectin type III-like domain	bgl2	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
IOLKFBCL_00918	216816.GS08_08015	0.0	878.0	COG3572@1|root,COG3572@2|Bacteria,2GJPI@201174|Actinobacteria,4CYZP@85004|Bifidobacteriales	201174|Actinobacteria	H	Glutamate-cysteine ligase family 2(GCS2)	egtA	GO:0003674,GO:0003824,GO:0004357,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0044464,GO:0071944	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3704c	GCS2
IOLKFBCL_00919	216816.GS08_08020	0.0	3204.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,2I1VH@201174|Actinobacteria,4CZ6Y@85004|Bifidobacteriales	201174|Actinobacteria	I	CoA enzyme activase uncharacterised domain (DUF2229)	hgdC	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229,HGD-D
IOLKFBCL_00920	326426.Bbr_1446	1.25e-183	509.0	COG0602@1|root,COG0602@2|Bacteria,2H0HA@201174|Actinobacteria,4CYSC@85004|Bifidobacteriales	201174|Actinobacteria	O	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	nrdG	-	1.97.1.4	ko:K04068	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
IOLKFBCL_00921	216816.GS08_08030	0.0	1645.0	COG1328@1|root,COG1328@2|Bacteria,2GMGA@201174|Actinobacteria,4CYV3@85004|Bifidobacteriales	201174|Actinobacteria	F	Anaerobic ribonucleoside-triphosphate reductase	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
IOLKFBCL_00922	216816.GS08_08035	0.0	880.0	COG1570@1|root,COG1570@2|Bacteria,2GJAS@201174|Actinobacteria,4CZU4@85004|Bifidobacteriales	201174|Actinobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
IOLKFBCL_00923	216816.GS08_08040	6.67e-58	180.0	COG1722@1|root,COG1722@2|Bacteria,2GR0U@201174|Actinobacteria,4D18C@85004|Bifidobacteriales	201174|Actinobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
IOLKFBCL_00924	216816.GS08_08045	8.95e-297	808.0	COG3550@1|root,COG3550@2|Bacteria,2GZFV@201174|Actinobacteria,4D1TH@85004|Bifidobacteriales	201174|Actinobacteria	S	peptidyl-serine autophosphorylation	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00925	216816.GS08_08055	1.4e-117	337.0	COG2249@1|root,COG2249@2|Bacteria,2HZE1@201174|Actinobacteria,4D11H@85004|Bifidobacteriales	201174|Actinobacteria	S	Flavodoxin-like fold	ywrO	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_2
IOLKFBCL_00926	216816.GS08_08060	0.0	1206.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4CYYC@85004|Bifidobacteriales	201174|Actinobacteria	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
IOLKFBCL_00927	216816.GS08_08070	8.33e-99	286.0	COG3613@1|root,COG3613@2|Bacteria,2IHGG@201174|Actinobacteria,4D0T2@85004|Bifidobacteriales	201174|Actinobacteria	F	Nucleoside 2-deoxyribosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Nuc_deoxyrib_tr
IOLKFBCL_00929	216816.GS08_08085	1.25e-245	677.0	COG3568@1|root,COG3568@2|Bacteria,2I2GX@201174|Actinobacteria,4CYTX@85004|Bifidobacteriales	201174|Actinobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	ko:K18353	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	Exo_endo_phos
IOLKFBCL_00930	216816.GS08_08090	4.21e-15	73.9	COG0248@1|root,COG0248@2|Bacteria,2GMME@201174|Actinobacteria,4CYW8@85004|Bifidobacteriales	201174|Actinobacteria	FP	Ppx/GppA phosphatase family	ppx1	GO:0003674,GO:0003824,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
IOLKFBCL_00931	326426.Bbr_1455	1.36e-10	61.2	COG0248@1|root,COG0248@2|Bacteria,2GMME@201174|Actinobacteria,4CYW8@85004|Bifidobacteriales	201174|Actinobacteria	FP	Ppx/GppA phosphatase family	ppx1	GO:0003674,GO:0003824,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
IOLKFBCL_00932	216816.GS08_08095	1.14e-294	804.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,4CZQP@85004|Bifidobacteriales	201174|Actinobacteria	E	Aminotransferase class-V	aspB	-	2.6.1.1,2.6.1.2,2.6.1.66	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
IOLKFBCL_00933	216816.GS08_08100	1.61e-252	692.0	COG0673@1|root,COG0673@2|Bacteria,2GKW0@201174|Actinobacteria,4CYXG@85004|Bifidobacteriales	201174|Actinobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
IOLKFBCL_00934	216816.GS08_08105	2.73e-109	315.0	COG3727@1|root,COG3727@2|Bacteria,2IKPY@201174|Actinobacteria,4D0R6@85004|Bifidobacteriales	201174|Actinobacteria	L	May nick specific sequences that contain T G mispairs resulting from m5C-deamination	vsr	-	-	ko:K07458	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Vsr
IOLKFBCL_00935	216816.GS08_08110	2.01e-47	154.0	COG0454@1|root,COG0456@2|Bacteria,2II91@201174|Actinobacteria,4D0SH@85004|Bifidobacteriales	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
IOLKFBCL_00936	216816.GS08_08115	4.04e-46	148.0	2A0ZE@1|root,30P4P@2|Bacteria,2I01I@201174|Actinobacteria,4D2N9@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00937	216816.GS08_08120	2.65e-103	299.0	COG1598@1|root,COG1598@2|Bacteria,2GRYW@201174|Actinobacteria,4D1K1@85004|Bifidobacteriales	201174|Actinobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00938	216816.GS08_08125	0.0	2682.0	COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,2GISC@201174|Actinobacteria,4CZSD@85004|Bifidobacteriales	201174|Actinobacteria	KL	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N,SNF2_assoc,SWIM
IOLKFBCL_00939	216816.GS08_08130	1.72e-268	734.0	COG2378@1|root,COG2378@2|Bacteria,2IAIA@201174|Actinobacteria,4CYRS@85004|Bifidobacteriales	201174|Actinobacteria	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	WYL
IOLKFBCL_00940	216816.GS08_08135	1.65e-223	618.0	COG2171@1|root,COG2171@2|Bacteria,2GIZ9@201174|Actinobacteria,4CYVT@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA	dapD	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008666,GO:0016020,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0030312,GO:0031402,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0048037,GO:0050662,GO:0071944	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1201c	Hexapep_2,THDPS_M
IOLKFBCL_00941	326426.Bbr_1462	3.68e-314	855.0	COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria,4CZ2J@85004|Bifidobacteriales	201174|Actinobacteria	C	Citrate synthase, C-terminal domain	gltA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
IOLKFBCL_00942	216816.GS08_08145	1.07e-193	536.0	COG0024@1|root,COG0024@2|Bacteria,2GKKB@201174|Actinobacteria,4CZAA@85004|Bifidobacteriales	201174|Actinobacteria	E	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
IOLKFBCL_00943	216816.GS08_08150	3.5e-184	518.0	COG3247@1|root,COG3247@2|Bacteria,2H3AT@201174|Actinobacteria,4D00R@85004|Bifidobacteriales	201174|Actinobacteria	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
IOLKFBCL_00944	216816.GS08_08155	0.0	1435.0	COG3590@1|root,COG3590@2|Bacteria,2GNJY@201174|Actinobacteria,4CYVU@85004|Bifidobacteriales	201174|Actinobacteria	O	Peptidase family M13	pepO	-	3.4.24.11,3.4.24.71	ko:K01389,ko:K01415,ko:K07386	ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	Peptidase_M13,Peptidase_M13_N
IOLKFBCL_00945	216816.GS08_08160	1.7e-70	223.0	COG0629@1|root,COG0629@2|Bacteria,2GQIQ@201174|Actinobacteria,4D17E@85004|Bifidobacteriales	201174|Actinobacteria	L	Single-strand binding protein family	ssb2	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
IOLKFBCL_00946	216816.GS08_08165	0.0	1177.0	COG0442@1|root,COG0442@2|Bacteria,2GJ9G@201174|Actinobacteria,4CZ6E@85004|Bifidobacteriales	201174|Actinobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
IOLKFBCL_00947	762211.BSTEL_1367	9.23e-30	120.0	COG3170@1|root,COG3170@2|Bacteria,2HZSX@201174|Actinobacteria,4D1MG@85004|Bifidobacteriales	201174|Actinobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00948	216816.GS08_08180	5.14e-43	153.0	COG1355@1|root,COG2078@1|root,COG1355@2|Bacteria,COG2078@2|Bacteria,2ISCW@201174|Actinobacteria,4D0HC@85004|Bifidobacteriales	201174|Actinobacteria	S	AMMECR1	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
IOLKFBCL_00949	216816.GS08_08180	3.44e-77	246.0	COG1355@1|root,COG2078@1|root,COG1355@2|Bacteria,COG2078@2|Bacteria,2ISCW@201174|Actinobacteria,4D0HC@85004|Bifidobacteriales	201174|Actinobacteria	S	AMMECR1	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
IOLKFBCL_00950	216816.GS08_08185	0.0	924.0	COG0507@1|root,COG0507@2|Bacteria,2HFY1@201174|Actinobacteria,4CZ0C@85004|Bifidobacteriales	201174|Actinobacteria	L	PIF1-like helicase	-	-	-	-	-	-	-	-	-	-	-	-	PIF1
IOLKFBCL_00951	326426.Bbr_1471	3.99e-149	420.0	COG1949@1|root,COG1949@2|Bacteria,2GJR7@201174|Actinobacteria,4CYZY@85004|Bifidobacteriales	201174|Actinobacteria	L	3'-to-5' exoribonuclease specific for small oligoribonucleotides	orn	GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
IOLKFBCL_00952	216816.GS08_08195	0.0	1003.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,2GITZ@201174|Actinobacteria,4CZ2S@85004|Bifidobacteriales	201174|Actinobacteria	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006183,GO:0006195,GO:0006204,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009125,GO:0009126,GO:0009127,GO:0009128,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009154,GO:0009156,GO:0009158,GO:0009161,GO:0009163,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009169,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009261,GO:0009987,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046037,GO:0046039,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:0097292,GO:0097293,GO:1901068,GO:1901070,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901659	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
IOLKFBCL_00953	216816.GS08_08200	2.46e-274	754.0	COG0472@1|root,COG0472@2|Bacteria,2GIT7@201174|Actinobacteria,4CZ4P@85004|Bifidobacteriales	201174|Actinobacteria	M	Glycosyl transferase family 4	rfe	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0034645,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
IOLKFBCL_00954	216816.GS08_08205	1.68e-154	434.0	COG0009@1|root,COG0009@2|Bacteria,2GK2X@201174|Actinobacteria,4CYVA@85004|Bifidobacteriales	201174|Actinobacteria	J	Belongs to the SUA5 family	ywlC	GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
IOLKFBCL_00955	1437610.BREU_1271	1.86e-128	368.0	COG0110@1|root,COG0110@2|Bacteria,2GNUB@201174|Actinobacteria,4CZ5K@85004|Bifidobacteriales	201174|Actinobacteria	S	Bacterial transferase hexapeptide repeat protein	-	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2,Mac
IOLKFBCL_00956	216816.GS08_08215	8.01e-227	624.0	COG2890@1|root,COG2890@2|Bacteria,2GMH1@201174|Actinobacteria,4CZB3@85004|Bifidobacteriales	201174|Actinobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_25,Methyltransf_31
IOLKFBCL_00957	216816.GS08_08220	1.59e-244	673.0	COG0216@1|root,COG0216@2|Bacteria,2GJWG@201174|Actinobacteria,4CYX4@85004|Bifidobacteriales	201174|Actinobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	GO:0008150,GO:0040007	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
IOLKFBCL_00958	216816.GS08_08225	6.44e-49	155.0	COG0254@1|root,COG0254@2|Bacteria,2IQ4I@201174|Actinobacteria,4D17F@85004|Bifidobacteriales	201174|Actinobacteria	J	Binds the 23S rRNA	rpmE	GO:0008150,GO:0040007	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
IOLKFBCL_00960	216816.GS08_08235	5.56e-287	785.0	COG1940@1|root,COG1940@2|Bacteria,2GJIE@201174|Actinobacteria,4CZPD@85004|Bifidobacteriales	201174|Actinobacteria	GK	ROK family	xylR	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,MarR_2,ROK
IOLKFBCL_00961	216816.GS08_08240	0.0	988.0	COG1070@1|root,COG1070@2|Bacteria,2GJDZ@201174|Actinobacteria,4CZH0@85004|Bifidobacteriales	201174|Actinobacteria	G	FGGY family of carbohydrate kinases, C-terminal domain	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
IOLKFBCL_00962	216816.GS08_08250	1.76e-40	137.0	2B0EM@1|root,31VWV@2|Bacteria,2GWC4@201174|Actinobacteria,4D1ED@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00963	1437610.BREU_1237	2.67e-49	159.0	2B5E2@1|root,31Y8I@2|Bacteria,2GQWF@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00964	216816.GS08_00895	1.59e-221	618.0	COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria,4D023@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
IOLKFBCL_00966	216816.GS08_08285	0.0	1311.0	COG1653@1|root,COG1653@2|Bacteria,2HT29@201174|Actinobacteria,4CZ28@85004|Bifidobacteriales	201174|Actinobacteria	G	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF1565
IOLKFBCL_00967	216816.GS08_08290	2.05e-139	395.0	COG0110@1|root,COG0110@2|Bacteria,2GNUB@201174|Actinobacteria,4CZ5K@85004|Bifidobacteriales	201174|Actinobacteria	S	Bacterial transferase hexapeptide repeat protein	maa	-	2.3.1.18,2.3.1.79	ko:K00633,ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2,Mac
IOLKFBCL_00968	216816.GS08_08295	0.0	1186.0	COG3507@1|root,COG3507@2|Bacteria,2GIW3@201174|Actinobacteria,4CZY8@85004|Bifidobacteriales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 43 family	-	-	3.2.1.37,3.2.1.55	ko:K01198,ko:K01209	ko00520,ko01100,map00520,map01100	-	R01433,R01762	RC00467	ko00000,ko00001,ko01000	-	GH43,GH51	-	Glyco_hydro_43
IOLKFBCL_00969	216816.GS08_08320	0.0	1096.0	COG3507@1|root,COG3507@2|Bacteria,2GIW3@201174|Actinobacteria,4CZ5I@85004|Bifidobacteriales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 43 family	-	-	3.2.1.37	ko:K01198	ko00520,ko01100,map00520,map01100	-	R01433	RC00467	ko00000,ko00001,ko01000	-	GH43	-	Glyco_hydro_43
IOLKFBCL_00970	401473.BDP_0567	1.41e-176	496.0	COG0395@1|root,COG0395@2|Bacteria,2GNQW@201174|Actinobacteria,4CZTW@85004|Bifidobacteriales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026,ko:K10119,ko:K17243	ko02010,map02010	M00196,M00207,M00600	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.28,3.A.1.1.39	-	-	BPD_transp_1
IOLKFBCL_00971	401473.BDP_0566	1.13e-188	529.0	COG1175@1|root,COG1175@2|Bacteria,2GKJI@201174|Actinobacteria,4CZQU@85004|Bifidobacteriales	201174|Actinobacteria	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K10118	ko02010,map02010	M00196,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.28	-	-	BPD_transp_1
IOLKFBCL_00972	401473.BDP_0565	9.34e-263	725.0	COG1653@1|root,COG1653@2|Bacteria,2GP9H@201174|Actinobacteria,4D01H@85004|Bifidobacteriales	201174|Actinobacteria	G	ABC transporter periplasmic binding protein YcjN precursor K02027	-	-	-	ko:K02027,ko:K10117	ko02010,map02010	M00196,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
IOLKFBCL_00973	216816.GS08_08340	2.08e-241	664.0	COG1609@1|root,COG1609@2|Bacteria,2GJRG@201174|Actinobacteria,4CZI0@85004|Bifidobacteriales	201174|Actinobacteria	K	Bacterial regulatory proteins, lacI family	-	-	-	ko:K02529,ko:K17640	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
IOLKFBCL_00974	216816.GS08_08345	8.04e-300	816.0	COG1979@1|root,COG1979@2|Bacteria,2IAN0@201174|Actinobacteria,4D02T@85004|Bifidobacteriales	201174|Actinobacteria	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
IOLKFBCL_00975	216816.GS08_08350	0.0	921.0	COG2115@1|root,COG2115@2|Bacteria,2GJCA@201174|Actinobacteria,4CZK8@85004|Bifidobacteriales	201174|Actinobacteria	G	Belongs to the xylose isomerase family	xylA	-	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
IOLKFBCL_00976	216816.GS08_08355	2.82e-44	144.0	COG0477@1|root,COG2814@2|Bacteria,2H8SZ@201174|Actinobacteria,4D2D2@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
IOLKFBCL_00977	1437609.BCAL_0501	3.78e-28	112.0	COG0477@1|root,COG2814@2|Bacteria,2GIZX@201174|Actinobacteria,4CZWX@85004|Bifidobacteriales	201174|Actinobacteria	U	Drug resistance MFS transporter, drug H antiporter-2 family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
IOLKFBCL_00978	216816.GS08_08365	5.51e-199	550.0	2A54I@1|root,30TT6@2|Bacteria,2IETW@201174|Actinobacteria,4CZX3@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00979	216816.GS08_08370	3.05e-95	277.0	COG0242@1|root,COG0242@2|Bacteria,2IJQ5@201174|Actinobacteria,4D14S@85004|Bifidobacteriales	201174|Actinobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins	fms	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
IOLKFBCL_00980	216816.GS08_08375	1.08e-209	578.0	COG0656@1|root,COG0656@2|Bacteria,2GJQ7@201174|Actinobacteria,4CYUN@85004|Bifidobacteriales	201174|Actinobacteria	S	Oxidoreductase, aldo keto reductase family protein	dkg	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
IOLKFBCL_00981	216816.GS08_08380	9.99e-176	491.0	COG0477@1|root,COG2814@2|Bacteria,2GIZX@201174|Actinobacteria,4D2XT@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
IOLKFBCL_00982	216816.GS08_08385	1.53e-118	338.0	COG1846@1|root,COG1846@2|Bacteria,2IHK6@201174|Actinobacteria,4D0T3@85004|Bifidobacteriales	201174|Actinobacteria	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR_2
IOLKFBCL_00983	216816.GS08_08390	1.37e-54	170.0	2B0EM@1|root,31SS1@2|Bacteria,2GR47@201174|Actinobacteria,4D1E7@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_00984	216816.GS08_08395	3.88e-253	699.0	COG4214@1|root,COG4214@2|Bacteria,2GJAH@201174|Actinobacteria,4D0EF@85004|Bifidobacteriales	201174|Actinobacteria	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10547	ko02010,map02010	M00216	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.5	-	-	BPD_transp_2
IOLKFBCL_00985	216816.GS08_08400	0.0	1015.0	COG1129@1|root,COG1129@2|Bacteria,2GJ3F@201174|Actinobacteria,4CZ8Y@85004|Bifidobacteriales	201174|Actinobacteria	G	ATPases associated with a variety of cellular activities	araG	-	3.6.3.17	ko:K10548	ko02010,map02010	M00216	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.5	-	-	ABC_tran
IOLKFBCL_00986	216816.GS08_08405	1.09e-274	751.0	COG4213@1|root,COG4213@2|Bacteria,2GKRE@201174|Actinobacteria,4CZW0@85004|Bifidobacteriales	201174|Actinobacteria	G	Periplasmic binding protein domain	-	-	-	ko:K10546	ko02010,map02010	M00216	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.5	-	-	Peripla_BP_4
IOLKFBCL_00987	216816.GS08_08410	2.47e-273	748.0	COG1940@1|root,COG1940@2|Bacteria,2GJ2S@201174|Actinobacteria,4CYV9@85004|Bifidobacteriales	201174|Actinobacteria	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,MarR_2,ROK
IOLKFBCL_00988	216816.GS08_08415	2.49e-197	548.0	COG1129@1|root,COG1129@2|Bacteria,2GJDV@201174|Actinobacteria,4CZ8T@85004|Bifidobacteriales	201174|Actinobacteria	G	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K02056,ko:K10545	ko02010,map02010	M00215,M00221	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2,3.A.1.2.4	-	-	ABC_tran
IOLKFBCL_00989	216816.GS08_08420	1.96e-224	619.0	COG1940@1|root,COG1940@2|Bacteria,2GJCQ@201174|Actinobacteria,4CZF6@85004|Bifidobacteriales	201174|Actinobacteria	G	ROK family	glkA	GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0051156,GO:0071704,GO:1901135	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
IOLKFBCL_00991	216816.GS08_08430	0.0	1030.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4D0BX@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
IOLKFBCL_00993	401473.BDP_1061	8.16e-78	238.0	COG1695@1|root,COG1695@2|Bacteria,2GNA1@201174|Actinobacteria,4D0ZC@85004|Bifidobacteriales	201174|Actinobacteria	K	Virulence activator alpha C-term	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
IOLKFBCL_00994	401473.BDP_1060	0.0	919.0	COG0577@1|root,COG0577@2|Bacteria,2GN24@201174|Actinobacteria,4D07Y@85004|Bifidobacteriales	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
IOLKFBCL_00995	216816.GS08_06345	3.4e-120	351.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4D06Q@85004|Bifidobacteriales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IOLKFBCL_00996	78346.BRUM_0133	2.41e-46	165.0	COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria,4D023@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
IOLKFBCL_00998	216816.GS08_04795	7.47e-262	720.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
IOLKFBCL_00999	216816.GS08_08435	0.0	1111.0	COG0488@1|root,COG0488@2|Bacteria,2GKBQ@201174|Actinobacteria,4CYWH@85004|Bifidobacteriales	201174|Actinobacteria	S	ATP-binding cassette protein, ChvD family	yjjK	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
IOLKFBCL_01000	216816.GS08_08440	2.56e-217	599.0	COG1946@1|root,COG1946@2|Bacteria,2GJ1B@201174|Actinobacteria,4CZRC@85004|Bifidobacteriales	201174|Actinobacteria	I	Thioesterase-like superfamily	tesB	-	-	ko:K10805	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT_3
IOLKFBCL_01001	216816.GS08_08445	3.16e-119	341.0	2DRQG@1|root,33CMQ@2|Bacteria,2HZP6@201174|Actinobacteria,4D14M@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3180)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3180
IOLKFBCL_01002	216816.GS08_08450	0.0	920.0	COG0801@1|root,COG1539@1|root,COG0801@2|Bacteria,COG1539@2|Bacteria,2H3G6@201174|Actinobacteria,4D0EJ@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folK	-	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB,HPPK
IOLKFBCL_01003	216816.GS08_08455	1.45e-202	561.0	COG0294@1|root,COG0294@2|Bacteria,2GJDQ@201174|Actinobacteria,4CZWW@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
IOLKFBCL_01004	216816.GS08_08460	2.43e-137	389.0	COG0302@1|root,COG0302@2|Bacteria,2GP2P@201174|Actinobacteria,4CZ5S@85004|Bifidobacteriales	201174|Actinobacteria	H	GTP cyclohydrolase	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3609c	GTP_cyclohydroI
IOLKFBCL_01006	216816.GS08_08470	0.0	1324.0	COG0465@1|root,COG0465@2|Bacteria,2GJ4Q@201174|Actinobacteria,4CZ6U@85004|Bifidobacteriales	201174|Actinobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0019538,GO:0030163,GO:0040007,GO:0042623,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
IOLKFBCL_01007	216816.GS08_08475	2.03e-124	355.0	COG0634@1|root,COG0634@2|Bacteria,2GMDZ@201174|Actinobacteria,4CZNJ@85004|Bifidobacteriales	201174|Actinobacteria	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
IOLKFBCL_01008	216816.GS08_08480	1.58e-264	726.0	COG0037@1|root,COG0037@2|Bacteria,2GJR4@201174|Actinobacteria,4CYSY@85004|Bifidobacteriales	201174|Actinobacteria	J	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	GO:0008150,GO:0040007	2.4.2.8,6.3.4.19	ko:K00760,ko:K04075	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245,R09597	RC00063,RC00122,RC02633,RC02634	ko00000,ko00001,ko01000,ko03016	-	-	-	ATP_bind_3,TilS
IOLKFBCL_01009	216816.GS08_08485	0.0	893.0	COG2027@1|root,COG2027@2|Bacteria,2GJPH@201174|Actinobacteria,4CYXQ@85004|Bifidobacteriales	201174|Actinobacteria	M	D-Ala-D-Ala carboxypeptidase 3 (S13) family	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
IOLKFBCL_01010	216816.GS08_08490	0.0	1041.0	2BWH2@1|root,2Z89R@2|Bacteria,2GMNW@201174|Actinobacteria,4CZP3@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
IOLKFBCL_01011	216816.GS08_08495	2.36e-206	573.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4CZ0Q@85004|Bifidobacteriales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	natA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IOLKFBCL_01012	216816.GS08_08500	1.33e-293	801.0	COG1215@1|root,COG1215@2|Bacteria,2HZ9V@201174|Actinobacteria,4CZ5J@85004|Bifidobacteriales	201174|Actinobacteria	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
IOLKFBCL_01013	216816.GS08_08505	0.0	981.0	COG0628@1|root,COG0628@2|Bacteria,2GN4Y@201174|Actinobacteria,4CZD1@85004|Bifidobacteriales	201174|Actinobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
IOLKFBCL_01014	216816.GS08_08510	3.82e-227	625.0	COG1215@1|root,COG1215@2|Bacteria,2GNPU@201174|Actinobacteria,4CZ7E@85004|Bifidobacteriales	201174|Actinobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
IOLKFBCL_01015	216816.GS08_08515	3.91e-267	732.0	COG1454@1|root,COG1454@2|Bacteria,2I2FD@201174|Actinobacteria,4CZ71@85004|Bifidobacteriales	201174|Actinobacteria	C	Iron-containing alcohol dehydrogenase	fucO	-	1.1.1.77,1.1.99.37,1.2.98.1	ko:K00048,ko:K17067	ko00625,ko00630,ko00640,ko00680,ko01120,ko01200,map00625,map00630,map00640,map00680,map01120,map01200	-	R00614,R01781,R02257	RC00034,RC00087,RC00099,RC00188	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
IOLKFBCL_01016	216816.GS08_08520	0.0	895.0	COG2230@1|root,COG2230@2|Bacteria,2GJ94@201174|Actinobacteria,4D016@85004|Bifidobacteriales	201174|Actinobacteria	M	Mycolic acid cyclopropane synthetase	cfa	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
IOLKFBCL_01019	216816.GS08_08535	5.63e-255	697.0	COG1087@1|root,COG1087@2|Bacteria,2GMCW@201174|Actinobacteria,4CZDB@85004|Bifidobacteriales	201174|Actinobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
IOLKFBCL_01020	216816.GS08_08540	8.11e-202	559.0	COG0220@1|root,COG0220@2|Bacteria,2GJ8R@201174|Actinobacteria,4CZKF@85004|Bifidobacteriales	201174|Actinobacteria	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
IOLKFBCL_01022	1437609.BCAL_0537	1.88e-42	143.0	2BH3J@1|root,32B4F@2|Bacteria,2IHK5@201174|Actinobacteria,4D0RP@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01026	1437609.BCAL_0608	5.42e-238	667.0	COG2865@1|root,COG2865@2|Bacteria,2GZ30@201174|Actinobacteria,4D2TR@85004|Bifidobacteriales	201174|Actinobacteria	K	Divergent AAA domain protein	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4
IOLKFBCL_01028	218140.BPSY_0351	9.2e-22	93.2	COG1215@1|root,COG1215@2|Bacteria,2I2IF@201174|Actinobacteria,4CYW6@85004|Bifidobacteriales	201174|Actinobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
IOLKFBCL_01030	78346.BRUM_1709	9.26e-45	146.0	2B5HD@1|root,31YC2@2|Bacteria,2HZU8@201174|Actinobacteria,4D1SC@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1
IOLKFBCL_01031	1437608.BBIA_1938	1.54e-83	258.0	COG4823@1|root,COG4823@2|Bacteria,2IDRD@201174|Actinobacteria,4D0BJ@85004|Bifidobacteriales	201174|Actinobacteria	V	Abi-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abi_2
IOLKFBCL_01032	1437609.BCAL_0716	1.76e-12	67.0	COG4823@1|root,COG4823@2|Bacteria,2IDRD@201174|Actinobacteria,4D0BJ@85004|Bifidobacteriales	201174|Actinobacteria	V	Abi-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abi_2
IOLKFBCL_01033	356851.JOAN01000003_gene1725	2.81e-60	209.0	COG2223@1|root,COG2223@2|Bacteria,2I3Y1@201174|Actinobacteria,4DB4I@85008|Micromonosporales	201174|Actinobacteria	P	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
IOLKFBCL_01035	996637.SGM_0992	8.36e-107	328.0	COG1181@1|root,COG1181@2|Bacteria,2IAF3@201174|Actinobacteria	201174|Actinobacteria	M	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp,ATP-grasp_4,CPSase_L_D2
IOLKFBCL_01037	326426.Bbr_1536	0.0	1088.0	COG3505@1|root,COG3505@2|Bacteria,2HZ9D@201174|Actinobacteria,4CZ1V@85004|Bifidobacteriales	201174|Actinobacteria	U	Type IV secretory system Conjugative DNA transfer	-	-	-	ko:K03205	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	T4SS-DNA_transf,TraG-D_C
IOLKFBCL_01039	326426.Bbr_1538	1.71e-65	199.0	2B4MV@1|root,31XE5@2|Bacteria,2GYVS@201174|Actinobacteria,4D1SI@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01040	326426.Bbr_1539	8.49e-57	186.0	COG4734@1|root,COG4734@2|Bacteria,2ICX2@201174|Actinobacteria,4D0K8@85004|Bifidobacteriales	201174|Actinobacteria	S	Antirestriction protein (ArdA)	-	-	-	-	-	-	-	-	-	-	-	-	ArdA
IOLKFBCL_01041	465515.Mlut_06470	3.01e-75	239.0	COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria,1W7QH@1268|Micrococcaceae	201174|Actinobacteria	L	PFAM Transposase, Mutator family	-	-	-	ko:K07493	-	-	-	-	ko00000	-	-	-	Transposase_mut
IOLKFBCL_01042	764298.STRMA_1492	8.17e-22	98.6	COG3425@1|root,COG3425@2|Bacteria,1UDNN@1239|Firmicutes	1239|Firmicutes	I	3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal	-	-	2.3.3.10	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	M00088,M00095	R01978	RC00004,RC00503	ko00000,ko00001,ko00002,ko01000	-	-	-	ACP_syn_III_C,DUF35_N,OB_aCoA_assoc
IOLKFBCL_01043	216816.GS08_05785	3.47e-229	632.0	COG3677@1|root,COG3677@2|Bacteria,2IEJD@201174|Actinobacteria,4CZTH@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
IOLKFBCL_01044	78344.BIGA_1651	3.44e-302	823.0	COG3464@1|root,COG3464@2|Bacteria,2IP45@201174|Actinobacteria,4D04T@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
IOLKFBCL_01045	216816.GS08_09320	4.62e-62	196.0	COG3464@1|root,COG3464@2|Bacteria,2IP45@201174|Actinobacteria,4D04T@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
IOLKFBCL_01046	216816.GS08_09320	1.27e-74	229.0	COG3464@1|root,COG3464@2|Bacteria,2IP45@201174|Actinobacteria,4D04T@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
IOLKFBCL_01047	1394176.AWUO01000004_gene959	4.25e-09	58.2	COG0477@1|root,COG2814@2|Bacteria,2GMR4@201174|Actinobacteria,4D03I@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
IOLKFBCL_01048	216816.GS08_06925	2.61e-197	546.0	COG0656@1|root,COG0656@2|Bacteria,2GJQ7@201174|Actinobacteria,4CZ1F@85004|Bifidobacteriales	201174|Actinobacteria	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
IOLKFBCL_01049	216816.GS08_06920	1.03e-197	560.0	COG1070@1|root,COG1070@2|Bacteria,2GNCR@201174|Actinobacteria,4D2SW@85004|Bifidobacteriales	201174|Actinobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
IOLKFBCL_01050	216816.GS08_06915	0.0	884.0	COG0141@1|root,COG0141@2|Bacteria,2GKKA@201174|Actinobacteria,4CZ3E@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1599	Histidinol_dh
IOLKFBCL_01051	216816.GS08_06910	1.1e-279	764.0	COG0079@1|root,COG0079@2|Bacteria,2GJ9W@201174|Actinobacteria,4CZDT@85004|Bifidobacteriales	201174|Actinobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
IOLKFBCL_01052	326426.Bbr_1283	2.75e-143	404.0	COG0131@1|root,COG0131@2|Bacteria,2GKMD@201174|Actinobacteria,4CZDD@85004|Bifidobacteriales	201174|Actinobacteria	E	Imidazoleglycerol-phosphate dehydratase	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.15,4.2.1.19	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013,R03457	RC00017,RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
IOLKFBCL_01053	216816.GS08_06900	4.01e-143	409.0	2EKCN@1|root,33E2Y@2|Bacteria,2GNIC@201174|Actinobacteria,4D0B5@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01054	216816.GS08_06895	1.77e-156	438.0	COG0118@1|root,COG0118@2|Bacteria,2GIYS@201174|Actinobacteria,4CZGA@85004|Bifidobacteriales	201174|Actinobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
IOLKFBCL_01055	216816.GS08_06890	1.96e-166	466.0	COG0106@1|root,COG0106@2|Bacteria,2GJ4V@201174|Actinobacteria,4CZEA@85004|Bifidobacteriales	201174|Actinobacteria	E	Histidine biosynthesis protein	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16,5.3.1.24	ko:K01814,ko:K01817	ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230	M00023,M00026	R03509,R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
IOLKFBCL_01056	216816.GS08_06885	3.61e-25	103.0	COG4320@1|root,COG4320@2|Bacteria,2GKEK@201174|Actinobacteria,4CZIY@85004|Bifidobacteriales	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2252
IOLKFBCL_01057	216816.GS08_06880	0.0	914.0	COG0174@1|root,COG0174@2|Bacteria,2GJ2I@201174|Actinobacteria,4CZ0G@85004|Bifidobacteriales	201174|Actinobacteria	E	glutamine synthetase	glnA2	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
IOLKFBCL_01058	216816.GS08_06875	4.72e-241	668.0	COG0477@1|root,COG2814@2|Bacteria,2GK8C@201174|Actinobacteria,4CZH1@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	ko:K18567,ko:K19577	-	-	-	-	ko00000,ko02000	2.A.1.2.25,2.A.1.2.65	-	-	MFS_1,Sugar_tr
IOLKFBCL_01059	158787.BSCA_1773	5.43e-176	495.0	COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria,4D071@85004|Bifidobacteriales	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	appC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
IOLKFBCL_01060	158787.BSCA_1774	3.25e-227	627.0	COG0601@1|root,COG0601@2|Bacteria,2GK0Z@201174|Actinobacteria,4D0MU@85004|Bifidobacteriales	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
IOLKFBCL_01061	158787.BSCA_1775	0.0	1083.0	COG0747@1|root,COG0747@2|Bacteria,2GJXH@201174|Actinobacteria,4D09J@85004|Bifidobacteriales	201174|Actinobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
IOLKFBCL_01062	158787.BSCA_1776	0.0	1037.0	COG1123@1|root,COG4172@2|Bacteria,2H3HY@201174|Actinobacteria,4CYU0@85004|Bifidobacteriales	201174|Actinobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
IOLKFBCL_01063	158787.BSCA_1777	4.56e-221	611.0	COG5479@1|root,COG5479@2|Bacteria,2HYIN@201174|Actinobacteria,4CYU1@85004|Bifidobacteriales	201174|Actinobacteria	M	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01064	216816.GS08_06830	0.0	2640.0	COG1643@1|root,COG1643@2|Bacteria,2GIWX@201174|Actinobacteria,4CZ3C@85004|Bifidobacteriales	201174|Actinobacteria	L	Helicase associated domain (HA2)  Add an annotation	hrpA	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	AAA_19,DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
IOLKFBCL_01065	216816.GS08_06825	3.86e-157	440.0	COG2813@1|root,COG2813@2|Bacteria,2IFG7@201174|Actinobacteria,4CZP1@85004|Bifidobacteriales	201174|Actinobacteria	J	Ribosomal protein L11 methyltransferase (PrmA)	rsmC	-	2.1.1.172	ko:K00564	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	MTS
IOLKFBCL_01066	216816.GS08_06820	0.0	944.0	COG2262@1|root,COG2262@2|Bacteria,2GK55@201174|Actinobacteria,4CZCB@85004|Bifidobacteriales	201174|Actinobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
IOLKFBCL_01067	216816.GS08_06815	4.62e-225	620.0	COG0039@1|root,COG0039@2|Bacteria,2GN5S@201174|Actinobacteria,4CYWK@85004|Bifidobacteriales	201174|Actinobacteria	C	Belongs to the LDH MDH superfamily. LDH family	ldh	-	1.1.1.27,1.1.1.37	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R00703,R01000,R03104,R07136	RC00031,RC00044	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
IOLKFBCL_01068	216816.GS08_06810	6.04e-201	559.0	COG1230@1|root,COG1230@2|Bacteria,2GMRZ@201174|Actinobacteria,4CZAB@85004|Bifidobacteriales	201174|Actinobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux,ZT_dimer
IOLKFBCL_01069	216816.GS08_06805	2.78e-166	465.0	COG1974@1|root,COG1974@2|Bacteria,2GMBN@201174|Actinobacteria,4CZ26@85004|Bifidobacteriales	201174|Actinobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
IOLKFBCL_01070	216816.GS08_06800	2.32e-70	213.0	COG1388@1|root,COG1388@2|Bacteria,2HVH4@201174|Actinobacteria,4D1G8@85004|Bifidobacteriales	201174|Actinobacteria	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
IOLKFBCL_01071	216816.GS08_06795	8.78e-64	196.0	COG1327@1|root,COG1327@2|Bacteria,2IHU9@201174|Actinobacteria,4D0P7@85004|Bifidobacteriales	201174|Actinobacteria	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
IOLKFBCL_01072	216816.GS08_06790	1.31e-289	790.0	COG0111@1|root,COG0111@2|Bacteria,2GJGA@201174|Actinobacteria,4CYPT@85004|Bifidobacteriales	201174|Actinobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
IOLKFBCL_01073	216816.GS08_06785	0.0	1461.0	COG3973@1|root,COG3973@2|Bacteria,2GK30@201174|Actinobacteria,4CYUF@85004|Bifidobacteriales	201174|Actinobacteria	L	DNA helicase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_19,UvrD_C_2,Viral_helicase1
IOLKFBCL_01074	216816.GS08_06780	3.86e-119	340.0	COG2001@1|root,COG2001@2|Bacteria,2IHUB@201174|Actinobacteria,4D0P1@85004|Bifidobacteriales	201174|Actinobacteria	K	Belongs to the MraZ family	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0040007,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
IOLKFBCL_01075	216816.GS08_06775	9.64e-249	684.0	COG0275@1|root,COG0275@2|Bacteria,2GJGK@201174|Actinobacteria,4CYRM@85004|Bifidobacteriales	201174|Actinobacteria	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
IOLKFBCL_01076	216816.GS08_06770	2.74e-96	281.0	COG2919@1|root,COG2919@2|Bacteria,2IKUA@201174|Actinobacteria,4D109@85004|Bifidobacteriales	201174|Actinobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01077	216816.GS08_06765	0.0	1153.0	COG0768@1|root,COG0768@2|Bacteria,2GKHH@201174|Actinobacteria,4CYS8@85004|Bifidobacteriales	201174|Actinobacteria	M	Penicillin-binding protein, transpeptidase domain protein	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
IOLKFBCL_01078	216816.GS08_06760	5.87e-197	547.0	COG0769@1|root,COG0769@2|Bacteria,2GMZF@201174|Actinobacteria,4CYWT@85004|Bifidobacteriales	201174|Actinobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01079	216816.GS08_06755	0.0	874.0	COG0770@1|root,COG0770@2|Bacteria,2GK0Y@201174|Actinobacteria,4CZ7U@85004|Bifidobacteriales	201174|Actinobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
IOLKFBCL_01080	216816.GS08_06750	7.84e-264	723.0	COG0472@1|root,COG0472@2|Bacteria,2GNEH@201174|Actinobacteria,4CYRX@85004|Bifidobacteriales	201174|Actinobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
IOLKFBCL_01081	216816.GS08_06745	0.0	937.0	COG0771@1|root,COG0771@2|Bacteria,2GJZA@201174|Actinobacteria,4CZKI@85004|Bifidobacteriales	201174|Actinobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iNJ661.Rv2155c	AlaDh_PNT_C,Mur_ligase_C,Mur_ligase_M
IOLKFBCL_01082	216816.GS08_06740	6.74e-286	781.0	COG0772@1|root,COG0772@2|Bacteria,2GKXP@201174|Actinobacteria,4CYPZ@85004|Bifidobacteriales	201174|Actinobacteria	D	Belongs to the SEDS family	ftsW	GO:0008150,GO:0040007	2.4.1.227	ko:K02563,ko:K03588	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011,ko02000,ko03036	2.A.103.1	GT28	-	FTSW_RODA_SPOVE
IOLKFBCL_01083	216816.GS08_06735	5.23e-277	758.0	COG0707@1|root,COG0707@2|Bacteria,2GJEM@201174|Actinobacteria,4CYQS@85004|Bifidobacteriales	201174|Actinobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227,6.3.2.8	ko:K01924,ko:K02563	ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112	-	R03193,R05032,R05662	RC00005,RC00049,RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
IOLKFBCL_01084	216816.GS08_06730	0.0	986.0	COG0773@1|root,COG0773@2|Bacteria,2I2E7@201174|Actinobacteria,4CZ3B@85004|Bifidobacteriales	201174|Actinobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
IOLKFBCL_01085	216816.GS08_06725	3.4e-235	649.0	COG1589@1|root,COG1589@2|Bacteria,2H4A4@201174|Actinobacteria,4D04A@85004|Bifidobacteriales	201174|Actinobacteria	D	Cell division protein FtsQ	ftsQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
IOLKFBCL_01087	216816.GS08_00985	1.85e-60	187.0	COG2963@1|root,COG2963@2|Bacteria,2IQ8F@201174|Actinobacteria,4D1BJ@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
IOLKFBCL_01088	398513.BBNG_00723	2.65e-185	519.0	COG2801@1|root,COG2801@2|Bacteria,2GKDY@201174|Actinobacteria,4CZUB@85004|Bifidobacteriales	201174|Actinobacteria	L	Integrase core domain	tnp3521a2	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve,rve_3
IOLKFBCL_01089	883069.HMPREF9238_01632	6.13e-138	399.0	COG1131@1|root,COG1131@2|Bacteria,2GJBF@201174|Actinobacteria,4D63Y@85005|Actinomycetales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IOLKFBCL_01090	883069.HMPREF9238_01633	3.46e-108	318.0	COG0842@1|root,COG0842@2|Bacteria,2HM0S@201174|Actinobacteria,4D65M@85005|Actinomycetales	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane
IOLKFBCL_01091	883069.HMPREF9238_01634	2.98e-46	168.0	COG1944@1|root,COG1944@2|Bacteria,2GKBS@201174|Actinobacteria	201174|Actinobacteria	S	YcaO cyclodehydratase, ATP-ad Mg2+-binding	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	YcaO
IOLKFBCL_01092	1437608.BBIA_1062	6.91e-45	153.0	COG2801@1|root,COG2801@2|Bacteria,2GKDY@201174|Actinobacteria,4CZUB@85004|Bifidobacteriales	201174|Actinobacteria	L	Integrase core domain	tnp3521a2	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve,rve_3
IOLKFBCL_01093	216816.GS08_09870	4.49e-259	709.0	COG4974@1|root,COG4974@2|Bacteria,2I9JH@201174|Actinobacteria,4D2KU@85004|Bifidobacteriales	201174|Actinobacteria	L	Phage integrase, N-terminal SAM-like domain	-	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
IOLKFBCL_01094	216816.GS08_03825	3.08e-244	669.0	COG0582@1|root,COG0582@2|Bacteria,2I9B8@201174|Actinobacteria,4D2Q1@85004|Bifidobacteriales	201174|Actinobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
IOLKFBCL_01095	216816.GS08_02215	1.94e-287	785.0	COG0582@1|root,COG0582@2|Bacteria,2HB7R@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
IOLKFBCL_01096	398513.BBNG_00723	1.73e-45	154.0	COG2801@1|root,COG2801@2|Bacteria,2GKDY@201174|Actinobacteria,4CZUB@85004|Bifidobacteriales	201174|Actinobacteria	L	Integrase core domain	tnp3521a2	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve,rve_3
IOLKFBCL_01097	561180.BIFGAL_04149	2.21e-157	455.0	COG0675@1|root,COG0675@2|Bacteria,2GM6K@201174|Actinobacteria,4D14G@85004|Bifidobacteriales	201174|Actinobacteria	L	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
IOLKFBCL_01098	471855.Shel_27760	9.95e-233	650.0	COG1373@1|root,COG1373@2|Bacteria,2HJ52@201174|Actinobacteria,4CUSM@84998|Coriobacteriia	84998|Coriobacteriia	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
IOLKFBCL_01101	33035.JPJF01000016_gene4117	6.64e-19	86.3	COG0145@1|root,COG0145@2|Bacteria,1TQVB@1239|Firmicutes,24AJ7@186801|Clostridia,3Y0KA@572511|Blautia	186801|Clostridia	EQ	Hydantoinase/oxoprolinase	-	-	-	-	-	-	-	-	-	-	-	-	Hydant_A_N,Hydantoinase_A
IOLKFBCL_01102	479437.Elen_0652	9.77e-35	132.0	COG0145@1|root,COG0145@2|Bacteria,2GIYE@201174|Actinobacteria,4CX45@84998|Coriobacteriia	84998|Coriobacteriia	EQ	Hydantoinase/oxoprolinase N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Hydant_A_N,Hydantoinase_A
IOLKFBCL_01103	518635.BIFANG_03327	7.31e-28	102.0	COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria,4D1MQ@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase and inactivated derivatives IS30 family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
IOLKFBCL_01104	702459.BBPR_0083	1.11e-163	463.0	COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria,4D0DN@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase and inactivated derivatives IS30 family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
IOLKFBCL_01105	398513.BBNG_00837	1.35e-82	247.0	COG1598@1|root,COG1598@2|Bacteria,2IPZP@201174|Actinobacteria,4D0YY@85004|Bifidobacteriales	201174|Actinobacteria	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
IOLKFBCL_01106	216816.GS08_06695	6.8e-110	316.0	COG1490@1|root,COG1490@2|Bacteria,2IKVR@201174|Actinobacteria,4D0VE@85004|Bifidobacteriales	201174|Actinobacteria	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
IOLKFBCL_01107	216816.GS08_06690	0.0	2051.0	COG0383@1|root,COG0383@2|Bacteria,2GM02@201174|Actinobacteria,4CYWB@85004|Bifidobacteriales	201174|Actinobacteria	G	Alpha mannosidase, middle domain	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
IOLKFBCL_01108	216816.GS08_06685	0.0	1876.0	COG0383@1|root,COG0383@2|Bacteria,2GM02@201174|Actinobacteria,4CYWB@85004|Bifidobacteriales	201174|Actinobacteria	G	Alpha mannosidase, middle domain	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
IOLKFBCL_01109	216816.GS08_06600	0.0	905.0	COG0747@1|root,COG0747@2|Bacteria,2GMAX@201174|Actinobacteria,4D2RC@85004|Bifidobacteriales	201174|Actinobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
IOLKFBCL_01110	518635.BIFANG_02623	3.78e-221	614.0	COG0601@1|root,COG0601@2|Bacteria,2GJ2C@201174|Actinobacteria,4CZSV@85004|Bifidobacteriales	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	dppB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
IOLKFBCL_01111	216816.GS08_06590	9.32e-231	641.0	COG1173@1|root,COG1173@2|Bacteria,2GKAW@201174|Actinobacteria,4CZ2Y@85004|Bifidobacteriales	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	dppC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
IOLKFBCL_01112	216816.GS08_06585	0.0	1027.0	COG1123@1|root,COG4172@2|Bacteria,2H3HY@201174|Actinobacteria,4CYU0@85004|Bifidobacteriales	201174|Actinobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
IOLKFBCL_01113	216816.GS08_06645	3.87e-208	582.0	COG1609@1|root,COG1609@2|Bacteria,2GJHF@201174|Actinobacteria,4CZCC@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
IOLKFBCL_01114	326426.Bbr_1140	8.39e-299	815.0	COG2942@1|root,COG2942@2|Bacteria,2GMJ7@201174|Actinobacteria,4CZNY@85004|Bifidobacteriales	201174|Actinobacteria	G	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)	-	-	-	-	-	-	-	-	-	-	-	-	GlcNAc_2-epim
IOLKFBCL_01115	326426.Bbr_1139	0.0	891.0	COG3538@1|root,COG3538@2|Bacteria,2HHAF@201174|Actinobacteria,4CZYN@85004|Bifidobacteriales	201174|Actinobacteria	S	Metal-independent alpha-mannosidase (GH125)	-	-	-	ko:K09704	-	-	-	-	ko00000	-	-	-	Glyco_hydro_125
IOLKFBCL_01116	216816.GS08_06630	1.66e-216	597.0	COG0524@1|root,COG0524@2|Bacteria,2HZB3@201174|Actinobacteria,4CZFC@85004|Bifidobacteriales	201174|Actinobacteria	G	pfkB family carbohydrate kinase	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
IOLKFBCL_01117	216816.GS08_06625	2.83e-282	772.0	COG1940@1|root,COG1940@2|Bacteria,2GJ2S@201174|Actinobacteria,4CYV9@85004|Bifidobacteriales	201174|Actinobacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HTH_24,MarR_2,ROK
IOLKFBCL_01118	216816.GS08_06620	7.17e-205	568.0	COG1940@1|root,COG1940@2|Bacteria,2GZ27@201174|Actinobacteria,4CZII@85004|Bifidobacteriales	201174|Actinobacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
IOLKFBCL_01119	216816.GS08_06615	6.36e-257	706.0	COG1940@1|root,COG1940@2|Bacteria,2GKMZ@201174|Actinobacteria,4CZUF@85004|Bifidobacteriales	201174|Actinobacteria	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	Crp,ROK
IOLKFBCL_01120	216816.GS08_06610	3.84e-192	533.0	COG0363@1|root,COG0363@2|Bacteria,2GK7F@201174|Actinobacteria,4CYYE@85004|Bifidobacteriales	201174|Actinobacteria	G	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
IOLKFBCL_01121	216816.GS08_06605	4.16e-297	811.0	COG1820@1|root,COG1820@2|Bacteria,2GK1E@201174|Actinobacteria,4CZKB@85004|Bifidobacteriales	201174|Actinobacteria	G	Amidohydrolase family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
IOLKFBCL_01122	1341695.BBOMB_1153	1.83e-253	703.0	COG1653@1|root,COG1653@2|Bacteria,2HZAD@201174|Actinobacteria,4CZ9S@85004|Bifidobacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
IOLKFBCL_01123	1341695.BBOMB_1154	1.18e-139	403.0	COG1175@1|root,COG1175@2|Bacteria,2GKJI@201174|Actinobacteria,4CZQU@85004|Bifidobacteriales	201174|Actinobacteria	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K10118	ko02010,map02010	M00196,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.28	-	-	BPD_transp_1
IOLKFBCL_01124	1341695.BBOMB_1155	5.24e-158	450.0	COG0395@1|root,COG0395@2|Bacteria,2I8S0@201174|Actinobacteria	201174|Actinobacteria	G	Binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
IOLKFBCL_01127	33876.JNXY01000003_gene178	1.98e-227	670.0	COG3669@1|root,COG3669@2|Bacteria	2|Bacteria	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,CBM_6,F5_F8_type_C,FIVAR,Glyco_hydro_106,Glyco_hydro_28,Melibiase_2
IOLKFBCL_01128	398513.BBNG_00491	1.47e-98	288.0	COG1051@1|root,COG1051@2|Bacteria,2IKKB@201174|Actinobacteria,4CZS4@85004|Bifidobacteriales	201174|Actinobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
IOLKFBCL_01129	216816.GS08_06575	0.0	1032.0	COG0006@1|root,COG0006@2|Bacteria,2GM7D@201174|Actinobacteria,4CZIA@85004|Bifidobacteriales	201174|Actinobacteria	E	Aminopeptidase P, N-terminal domain	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
IOLKFBCL_01130	216816.GS08_06570	1.3e-202	563.0	COG5340@1|root,COG5340@2|Bacteria,2ICPH@201174|Actinobacteria,4CZJ7@85004|Bifidobacteriales	201174|Actinobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01131	216816.GS08_06565	0.0	993.0	COG0285@1|root,COG0285@2|Bacteria,2GJP2@201174|Actinobacteria,4CZG9@85004|Bifidobacteriales	201174|Actinobacteria	H	Mur ligase middle domain	folC	GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2447c	Mur_ligase_C,Mur_ligase_M
IOLKFBCL_01132	216816.GS08_06560	0.0	2003.0	COG1196@1|root,COG1196@2|Bacteria,2GK93@201174|Actinobacteria,4CZ8Q@85004|Bifidobacteriales	201174|Actinobacteria	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
IOLKFBCL_01133	216816.GS08_06555	1.36e-243	668.0	COG2348@1|root,COG2348@2|Bacteria,2GJUD@201174|Actinobacteria,4CZT9@85004|Bifidobacteriales	201174|Actinobacteria	V	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6,FemAB
IOLKFBCL_01134	216816.GS08_06550	0.0	1008.0	COG0769@1|root,COG0769@2|Bacteria,2GIS2@201174|Actinobacteria,4CZAF@85004|Bifidobacteriales	201174|Actinobacteria	M	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
IOLKFBCL_01135	216816.GS08_06545	1.54e-172	483.0	COG1595@1|root,COG1595@2|Bacteria,2GJ02@201174|Actinobacteria,4CZ09@85004|Bifidobacteriales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigH	GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
IOLKFBCL_01136	216816.GS08_06540	6.7e-72	216.0	29M53@1|root,3082I@2|Bacteria,2GTWX@201174|Actinobacteria,4D1EJ@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01137	216816.GS08_06535	3.18e-238	653.0	COG2017@1|root,COG2017@2|Bacteria,2GJ0H@201174|Actinobacteria,4CYWN@85004|Bifidobacteriales	201174|Actinobacteria	G	Aldose 1-epimerase	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
IOLKFBCL_01138	216816.GS08_06530	4.72e-242	663.0	COG2017@1|root,COG2017@2|Bacteria,2GJ0H@201174|Actinobacteria,4CYWN@85004|Bifidobacteriales	201174|Actinobacteria	G	Aldose 1-epimerase	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
IOLKFBCL_01139	216816.GS08_06525	1.37e-227	628.0	COG0761@1|root,COG0761@2|Bacteria,2GIZ7@201174|Actinobacteria,4CZ8B@85004|Bifidobacteriales	201174|Actinobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
IOLKFBCL_01140	216816.GS08_06430	5.31e-115	330.0	COG2606@1|root,COG2606@2|Bacteria,2IHS8@201174|Actinobacteria,4CZFI@85004|Bifidobacteriales	201174|Actinobacteria	J	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily	ybaK	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
IOLKFBCL_01141	216816.GS08_06425	1.05e-253	696.0	COG0057@1|root,COG0057@2|Bacteria,2GJK4@201174|Actinobacteria,4CZ97@85004|Bifidobacteriales	201174|Actinobacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
IOLKFBCL_01142	216816.GS08_06420	1.82e-171	478.0	COG1564@1|root,COG1564@2|Bacteria,2HQZZ@201174|Actinobacteria,4CZBY@85004|Bifidobacteriales	201174|Actinobacteria	H	Thiamin pyrophosphokinase, vitamin B1 binding domain	-	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
IOLKFBCL_01143	216816.GS08_06415	3.43e-111	323.0	COG0290@1|root,COG0290@2|Bacteria,2GJGT@201174|Actinobacteria,4CZA3@85004|Bifidobacteriales	201174|Actinobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
IOLKFBCL_01144	216816.GS08_06410	1.4e-36	123.0	COG0291@1|root,COG0291@2|Bacteria,2HZRM@201174|Actinobacteria,4D1EV@85004|Bifidobacteriales	201174|Actinobacteria	J	Ribosomal protein L35	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
IOLKFBCL_01145	216816.GS08_06405	7.76e-81	240.0	COG0292@1|root,COG0292@2|Bacteria,2IHTN@201174|Actinobacteria,4D0QF@85004|Bifidobacteriales	201174|Actinobacteria	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016020,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0071944,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
IOLKFBCL_01146	216816.GS08_06400	2.09e-215	595.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4CZ69@85004|Bifidobacteriales	201174|Actinobacteria	D	recombinase XerD	xerD	GO:0008150,GO:0040007	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
IOLKFBCL_01147	216816.GS08_06395	8.08e-193	537.0	COG1192@1|root,COG1192@2|Bacteria,2GJX3@201174|Actinobacteria,4CYV4@85004|Bifidobacteriales	201174|Actinobacteria	D	CobQ CobB MinD ParA nucleotide binding domain protein	soj	GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
IOLKFBCL_01148	216816.GS08_06390	2.2e-199	554.0	COG1354@1|root,COG1354@2|Bacteria,2GN1U@201174|Actinobacteria,4CYRV@85004|Bifidobacteriales	201174|Actinobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
IOLKFBCL_01149	216816.GS08_06385	2.14e-148	420.0	COG1386@1|root,COG1386@2|Bacteria,2GISY@201174|Actinobacteria,4D0QW@85004|Bifidobacteriales	201174|Actinobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
IOLKFBCL_01150	216816.GS08_06380	7.49e-197	545.0	COG1051@1|root,COG1051@2|Bacteria,2GNMT@201174|Actinobacteria,4CZNZ@85004|Bifidobacteriales	201174|Actinobacteria	F	NUDIX hydrolase	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
IOLKFBCL_01151	216816.GS08_06375	0.0	867.0	COG0379@1|root,COG0379@2|Bacteria,2GM59@201174|Actinobacteria,4D0AI@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
IOLKFBCL_01152	216816.GS08_06370	0.0	1036.0	COG0029@1|root,COG0029@2|Bacteria,2I2IJ@201174|Actinobacteria,4D01P@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	GO:0008150,GO:0040007	1.4.3.16,2.4.2.19	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481,R03348	RC00006,RC02566,RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1595	FAD_binding_2,Succ_DH_flav_C
IOLKFBCL_01153	216816.GS08_06365	1.07e-207	575.0	COG0157@1|root,COG0157@2|Bacteria,2GV9P@201174|Actinobacteria,4CZWA@85004|Bifidobacteriales	201174|Actinobacteria	H	Quinolinate phosphoribosyl transferase, N-terminal domain	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
IOLKFBCL_01154	216816.GS08_06360	3.1e-271	745.0	COG1104@1|root,COG1104@2|Bacteria,2GKUT@201174|Actinobacteria,4CZVW@85004|Bifidobacteriales	201174|Actinobacteria	E	Aminotransferase class-V	iscS1	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
IOLKFBCL_01155	216816.GS08_06335	0.0	1262.0	COG1217@1|root,COG1217@2|Bacteria,2GJUJ@201174|Actinobacteria,4CYX3@85004|Bifidobacteriales	201174|Actinobacteria	T	Elongation factor G C-terminus	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
IOLKFBCL_01157	77635.BISU_1622	6.31e-46	162.0	COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,2GKW1@201174|Actinobacteria,4D05P@85004|Bifidobacteriales	201174|Actinobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,HTH_28,rve,rve_2
IOLKFBCL_01158	216816.GS08_06330	2.17e-97	283.0	2E9EF@1|root,333MW@2|Bacteria,2IKWQ@201174|Actinobacteria,4D10T@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01159	216816.GS08_06325	1.52e-243	667.0	COG0077@1|root,COG0077@2|Bacteria,2GJQ5@201174|Actinobacteria,4CZ61@85004|Bifidobacteriales	201174|Actinobacteria	E	Prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDT
IOLKFBCL_01160	216816.GS08_06320	2.47e-240	661.0	COG0287@1|root,COG0287@2|Bacteria,2GKB4@201174|Actinobacteria,4CYV2@85004|Bifidobacteriales	201174|Actinobacteria	E	Prephenate dehydrogenase	tyrA	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.3.1.12	ko:K00210,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
IOLKFBCL_01161	216816.GS08_06315	3.75e-57	177.0	2BGJ3@1|root,32AHC@2|Bacteria,2IR91@201174|Actinobacteria,4D17H@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01162	216816.GS08_06310	6.16e-238	656.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4CZCX@85004|Bifidobacteriales	201174|Actinobacteria	D	Belongs to the 'phage' integrase family. XerC subfamily	xerC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
IOLKFBCL_01163	216816.GS08_06305	0.0	1070.0	COG4166@1|root,COG4166@2|Bacteria,2GIUH@201174|Actinobacteria,4CZFK@85004|Bifidobacteriales	201174|Actinobacteria	E	ABC transporter, substrate-binding protein, family 5	dppA	-	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
IOLKFBCL_01164	216816.GS08_06300	1.89e-202	562.0	COG0601@1|root,COG0601@2|Bacteria,2GJ2C@201174|Actinobacteria,4CZSV@85004|Bifidobacteriales	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	dppB	-	-	ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
IOLKFBCL_01165	326426.Bbr_1203	1.82e-229	633.0	COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria,4CYQF@85004|Bifidobacteriales	201174|Actinobacteria	EP	N-terminal TM domain of oligopeptide transport permease C	dppC	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
IOLKFBCL_01166	326426.Bbr_1202	0.0	1283.0	COG0444@1|root,COG1123@1|root,COG0444@2|Bacteria,COG4172@2|Bacteria,2GIXV@201174|Actinobacteria,4D2V0@85004|Bifidobacteriales	201174|Actinobacteria	EP	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
IOLKFBCL_01167	216816.GS08_06285	1.08e-215	594.0	COG0708@1|root,COG0708@2|Bacteria,2GKIS@201174|Actinobacteria,4CYVB@85004|Bifidobacteriales	201174|Actinobacteria	L	Endonuclease/Exonuclease/phosphatase family	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
IOLKFBCL_01168	216816.GS08_06280	2.45e-186	520.0	28J4D@1|root,30NZ9@2|Bacteria,2I2E9@201174|Actinobacteria,4D2VD@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3710)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3710
IOLKFBCL_01169	216816.GS08_06275	2.19e-156	442.0	2AVV0@1|root,31MNQ@2|Bacteria,2GJKP@201174|Actinobacteria,4CYQX@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3159
IOLKFBCL_01170	216816.GS08_06270	4.96e-308	839.0	COG2265@1|root,COG2265@2|Bacteria,2GIR3@201174|Actinobacteria,4CYYN@85004|Bifidobacteriales	201174|Actinobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
IOLKFBCL_01171	216816.GS08_06265	2.54e-148	419.0	2AVVG@1|root,31MP9@2|Bacteria,2INFG@201174|Actinobacteria,4D12J@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
IOLKFBCL_01172	216816.GS08_06260	0.0	1412.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4CYS1@85004|Bifidobacteriales	201174|Actinobacteria	P	E1-E2 ATPase	ctpE	GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	-	ko:K12952	-	-	-	-	ko00000,ko01000	3.A.3.23	-	-	E1-E2_ATPase,Hydrolase
IOLKFBCL_01173	216816.GS08_06255	0.0	1803.0	COG1048@1|root,COG1048@2|Bacteria,2GJD5@201174|Actinobacteria,4CZ3T@85004|Bifidobacteriales	201174|Actinobacteria	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008198,GO:0009060,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0030312,GO:0030350,GO:0032787,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
IOLKFBCL_01174	216816.GS08_06250	4.99e-76	227.0	COG3077@1|root,COG3077@2|Bacteria,2IT2R@201174|Actinobacteria,4D175@85004|Bifidobacteriales	201174|Actinobacteria	L	RelB antitoxin	-	-	-	-	-	-	-	-	-	-	-	-	RelB
IOLKFBCL_01175	216816.GS08_06245	1.8e-110	318.0	COG2402@1|root,COG2402@2|Bacteria,2I5GT@201174|Actinobacteria,4D2B6@85004|Bifidobacteriales	201174|Actinobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
IOLKFBCL_01176	216816.GS08_06240	0.0	1387.0	COG1479@1|root,COG1479@2|Bacteria,2I99F@201174|Actinobacteria,4CZ4G@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function DUF262	-	-	-	-	-	-	-	-	-	-	-	-	DUF1524,DUF262
IOLKFBCL_01177	216816.GS08_06235	1.11e-152	429.0	COG1246@1|root,COG1246@2|Bacteria,2I61X@201174|Actinobacteria,4D2U1@85004|Bifidobacteriales	201174|Actinobacteria	E	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
IOLKFBCL_01178	216816.GS08_06225	2.62e-189	528.0	COG0670@1|root,COG0670@2|Bacteria,2I98Y@201174|Actinobacteria,4CZIJ@85004|Bifidobacteriales	201174|Actinobacteria	S	Belongs to the BI1 family	-	-	-	ko:K06890	-	-	-	-	ko00000	-	-	-	Bax1-I
IOLKFBCL_01179	216816.GS08_06220	2.77e-226	625.0	COG0697@1|root,COG0697@2|Bacteria,2I8X5@201174|Actinobacteria,4D0BH@85004|Bifidobacteriales	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
IOLKFBCL_01180	216816.GS08_06215	2.32e-174	488.0	COG2357@1|root,COG2357@2|Bacteria,2GKF8@201174|Actinobacteria,4CYXP@85004|Bifidobacteriales	201174|Actinobacteria	S	Region found in RelA / SpoT proteins	ywaC	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
IOLKFBCL_01181	216816.GS08_06210	0.0	952.0	COG0621@1|root,COG0621@2|Bacteria,2GJEV@201174|Actinobacteria,4CZFB@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
IOLKFBCL_01182	216816.GS08_06205	3.56e-233	642.0	COG0324@1|root,COG0324@2|Bacteria,2GKFT@201174|Actinobacteria,4CZNS@85004|Bifidobacteriales	201174|Actinobacteria	F	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
IOLKFBCL_01183	216816.GS08_06200	7.92e-175	487.0	COG2184@1|root,COG2184@2|Bacteria,2IN0D@201174|Actinobacteria,4D03T@85004|Bifidobacteriales	201174|Actinobacteria	D	Fic/DOC family	fic	-	-	ko:K04095	-	-	-	-	ko00000,ko03036	-	-	-	Fic
IOLKFBCL_01184	216816.GS08_06195	0.0	1805.0	COG1674@1|root,COG1674@2|Bacteria,2GK3T@201174|Actinobacteria,4CZ5T@85004|Bifidobacteriales	201174|Actinobacteria	D	FtsK SpoIIIE family protein	ftsK	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
IOLKFBCL_01185	216816.GS08_06190	4.82e-151	424.0	COG0558@1|root,COG0558@2|Bacteria,2GK5D@201174|Actinobacteria,4CZ36@85004|Bifidobacteriales	201174|Actinobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
IOLKFBCL_01186	216816.GS08_06185	2.13e-118	339.0	COG1546@1|root,COG1546@2|Bacteria,2IQ8T@201174|Actinobacteria,4D0CM@85004|Bifidobacteriales	201174|Actinobacteria	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA
IOLKFBCL_01187	216816.GS08_06180	1.06e-106	309.0	COG1426@1|root,COG1426@2|Bacteria,2I2G5@201174|Actinobacteria,4D0PT@85004|Bifidobacteriales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
IOLKFBCL_01188	216816.GS08_06175	4.64e-52	163.0	2EFU9@1|root,339KE@2|Bacteria,2GQJW@201174|Actinobacteria,4D16T@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3046)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3046
IOLKFBCL_01189	216816.GS08_06170	2.91e-260	716.0	COG0468@1|root,COG0468@2|Bacteria,2GJ4P@201174|Actinobacteria,4CYYY@85004|Bifidobacteriales	201174|Actinobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
IOLKFBCL_01190	216816.GS08_06165	3.06e-130	370.0	COG2137@1|root,COG2137@2|Bacteria,2INKM@201174|Actinobacteria,4D0Y4@85004|Bifidobacteriales	201174|Actinobacteria	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
IOLKFBCL_01191	216816.GS08_06160	1.24e-154	434.0	COG1544@1|root,COG1544@2|Bacteria,2GMYF@201174|Actinobacteria,4CZ3H@85004|Bifidobacteriales	201174|Actinobacteria	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
IOLKFBCL_01192	216816.GS08_06155	0.0	1826.0	COG0653@1|root,COG0653@2|Bacteria,2GIRT@201174|Actinobacteria,4CYX6@85004|Bifidobacteriales	201174|Actinobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
IOLKFBCL_01193	1437608.BBIA_0938	3.93e-82	250.0	COG2755@1|root,COG2755@2|Bacteria,2IDIX@201174|Actinobacteria	201174|Actinobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
IOLKFBCL_01194	158787.BSCA_1512	4.3e-219	608.0	COG0547@1|root,COG0547@2|Bacteria,2GM4G@201174|Actinobacteria,4CZKZ@85004|Bifidobacteriales	201174|Actinobacteria	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
IOLKFBCL_01195	326426.Bbr_1176	9.83e-110	321.0	2AP35@1|root,31E4N@2|Bacteria,2IBUY@201174|Actinobacteria,4D0R7@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01196	216816.GS08_06120	1.56e-166	465.0	COG0204@1|root,COG0204@2|Bacteria,2GJ6V@201174|Actinobacteria,4CZBB@85004|Bifidobacteriales	201174|Actinobacteria	I	Phosphate acyltransferases	plsC2	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
IOLKFBCL_01197	216816.GS08_06115	0.0	1371.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4CYTR@85004|Bifidobacteriales	201174|Actinobacteria	KLT	PASTA	pknL	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
IOLKFBCL_01198	216816.GS08_06110	4.54e-243	669.0	COG0142@1|root,COG0142@2|Bacteria,2GJEK@201174|Actinobacteria,4CZQV@85004|Bifidobacteriales	201174|Actinobacteria	H	Belongs to the FPP GGPP synthase family	idsA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
IOLKFBCL_01199	216816.GS08_06105	1.1e-157	442.0	2B5AP@1|root,31Y4U@2|Bacteria,2IF9M@201174|Actinobacteria,4D15J@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4192
IOLKFBCL_01200	216816.GS08_06100	1.03e-243	680.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4CZQC@85004|Bifidobacteriales	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
IOLKFBCL_01201	216816.GS08_06095	0.0	1483.0	COG0187@1|root,COG0187@2|Bacteria,2GM1E@201174|Actinobacteria,4CYXR@85004|Bifidobacteriales	201174|Actinobacteria	L	DNA topoisomerase (ATP-hydrolyzing)	gyrB2	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
IOLKFBCL_01202	216816.GS08_06090	1.29e-264	728.0	COG0738@1|root,COG0738@2|Bacteria,2HWKN@201174|Actinobacteria,4CYRZ@85004|Bifidobacteriales	201174|Actinobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
IOLKFBCL_01203	216816.GS08_06085	2.92e-219	606.0	COG0524@1|root,COG0524@2|Bacteria,2I04R@201174|Actinobacteria,4CZIB@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
IOLKFBCL_01204	216816.GS08_06080	0.0	3012.0	COG1201@1|root,COG1201@2|Bacteria,2GJG3@201174|Actinobacteria,4D01F@85004|Bifidobacteriales	201174|Actinobacteria	L	DEAD DEAH box helicase	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,HTH_42,Helicase_C
IOLKFBCL_01205	216816.GS08_06075	1.05e-160	453.0	COG0745@1|root,COG0745@2|Bacteria,2ISFD@201174|Actinobacteria,4D188@85004|Bifidobacteriales	201174|Actinobacteria	KT	RESPONSE REGULATOR receiver	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
IOLKFBCL_01206	216816.GS08_06070	0.0	1722.0	COG0188@1|root,COG0188@2|Bacteria,2GJ2Q@201174|Actinobacteria,4CYVH@85004|Bifidobacteriales	201174|Actinobacteria	L	DNA topoisomerase (ATP-hydrolyzing)	gyrA2	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
IOLKFBCL_01207	216816.GS08_06065	3.02e-298	814.0	COG1524@1|root,COG1524@2|Bacteria,2GISU@201174|Actinobacteria,4CZCK@85004|Bifidobacteriales	201174|Actinobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
IOLKFBCL_01208	216816.GS08_06060	1.44e-236	653.0	29W72@1|root,30HS9@2|Bacteria,2HZB4@201174|Actinobacteria,4CZFJ@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3071)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3071
IOLKFBCL_01209	216816.GS08_06055	1.42e-62	191.0	2ATJW@1|root,3361K@2|Bacteria,2I80Y@201174|Actinobacteria,4D10Y@85004|Bifidobacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4193)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4193
IOLKFBCL_01210	326426.Bbr_1158	1.62e-106	307.0	COG0756@1|root,COG0756@2|Bacteria,2IHYY@201174|Actinobacteria,4CZUJ@85004|Bifidobacteriales	201174|Actinobacteria	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
IOLKFBCL_01211	216816.GS08_06045	0.0	1507.0	COG0317@1|root,COG0317@2|Bacteria,2GJYQ@201174|Actinobacteria,4CZCW@85004|Bifidobacteriales	201174|Actinobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009259,GO:0009260,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0015969,GO:0015970,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034035,GO:0034036,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042578,GO:0042594,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044419,GO:0044464,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051704,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
IOLKFBCL_01212	326426.Bbr_1156	5.43e-122	348.0	COG0652@1|root,COG0652@2|Bacteria,2IFUE@201174|Actinobacteria,4CZSU@85004|Bifidobacteriales	201174|Actinobacteria	G	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030312,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0071944,GO:0140096,GO:1901564	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
IOLKFBCL_01213	216816.GS08_05970	1.53e-97	283.0	2ATF2@1|root,31IYI@2|Bacteria,2IIKG@201174|Actinobacteria,4D0ZG@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01215	326426.Bbr_1154	5.6e-308	840.0	COG3550@1|root,COG3550@2|Bacteria,2IEM1@201174|Actinobacteria,4CZPH@85004|Bifidobacteriales	201174|Actinobacteria	S	HipA-like C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	HipA_C
IOLKFBCL_01216	216816.GS08_05955	6.19e-145	412.0	COG3177@1|root,COG3177@2|Bacteria,2ICFW@201174|Actinobacteria,4D01T@85004|Bifidobacteriales	201174|Actinobacteria	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
IOLKFBCL_01217	1235799.C818_00076	4.94e-103	300.0	COG1695@1|root,COG1695@2|Bacteria,1V1R5@1239|Firmicutes,24FU3@186801|Clostridia,27MDD@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_34,PadR,Vir_act_alpha_C
IOLKFBCL_01218	553973.CLOHYLEM_07146	1.59e-137	394.0	COG0300@1|root,COG0300@2|Bacteria,1UZHA@1239|Firmicutes,248C8@186801|Clostridia,21YNY@1506553|Lachnoclostridium	186801|Clostridia	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
IOLKFBCL_01219	411461.DORFOR_03070	2.19e-196	556.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
IOLKFBCL_01220	216816.GS08_05955	6.21e-47	158.0	COG3177@1|root,COG3177@2|Bacteria,2ICFW@201174|Actinobacteria,4D01T@85004|Bifidobacteriales	201174|Actinobacteria	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
IOLKFBCL_01222	216816.GS08_06000	5.35e-305	832.0	COG0477@1|root,COG2814@2|Bacteria,2I8QF@201174|Actinobacteria,4CZF1@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
IOLKFBCL_01223	216816.GS08_05995	3.91e-46	149.0	COG3177@1|root,COG3177@2|Bacteria	2|Bacteria	D	Filamentation induced by cAMP protein fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic
IOLKFBCL_01224	78344.BIGA_0334	1.44e-259	714.0	COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria,4D023@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
IOLKFBCL_01225	547043.BIFPSEUDO_03929	3.96e-15	71.6	COG2189@1|root,COG2189@2|Bacteria	2|Bacteria	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.72	ko:K07316	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
IOLKFBCL_01227	547043.BIFPSEUDO_03926	1.53e-35	120.0	2B0NT@1|root,31T0I@2|Bacteria,2GRGK@201174|Actinobacteria,4D1EC@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01228	547043.BIFPSEUDO_03925	8.73e-186	516.0	COG2184@1|root,COG2184@2|Bacteria,2IN0D@201174|Actinobacteria,4D03T@85004|Bifidobacteriales	201174|Actinobacteria	D	Fic/DOC family	fic	-	-	ko:K04095	-	-	-	-	ko00000,ko03036	-	-	-	Fic
IOLKFBCL_01229	547043.BIFPSEUDO_03924	0.0	908.0	COG0582@1|root,COG0582@2|Bacteria,2GISN@201174|Actinobacteria,4CZA9@85004|Bifidobacteriales	201174|Actinobacteria	L	Phage integrase family	intA	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
IOLKFBCL_01230	547043.BIFPSEUDO_03226	4.72e-45	153.0	COG1175@1|root,COG1175@2|Bacteria,2GMTW@201174|Actinobacteria,4CZW4@85004|Bifidobacteriales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
IOLKFBCL_01231	216816.GS08_04275	3.62e-249	687.0	COG4260@1|root,COG4260@2|Bacteria,2HUEV@201174|Actinobacteria,4CZKS@85004|Bifidobacteriales	201174|Actinobacteria	S	Short C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DUF4339,SHOCT
IOLKFBCL_01232	216816.GS08_04270	1.43e-51	162.0	2C3F9@1|root,2ZWBA@2|Bacteria,2H1CK@201174|Actinobacteria,4D1N7@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01233	216816.GS08_04265	2.72e-285	789.0	2DNFW@1|root,32XAQ@2|Bacteria,2IANA@201174|Actinobacteria,4D0ED@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01234	326426.Bbr_0840	2.87e-101	293.0	2E529@1|root,32ZVG@2|Bacteria,2IIU2@201174|Actinobacteria,4D0Z5@85004|Bifidobacteriales	201174|Actinobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
IOLKFBCL_01235	216816.GS08_04255	0.0	987.0	COG0515@1|root,COG0515@2|Bacteria,2IB6I@201174|Actinobacteria,4D0BZ@85004|Bifidobacteriales	201174|Actinobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
IOLKFBCL_01236	216816.GS08_04250	0.0	901.0	COG0477@1|root,COG0477@2|Bacteria,2GK06@201174|Actinobacteria,4D2W9@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	ko:K08217	-	-	-	-	br01600,ko00000,ko01504,ko02000	2.A.1.21.1,2.A.1.21.22	-	-	MFS_1,MFS_3
IOLKFBCL_01237	216816.GS08_04245	0.0	1233.0	COG0477@1|root,COG0517@1|root,COG0517@2|Bacteria,COG2814@2|Bacteria,2GIZX@201174|Actinobacteria,4CZWX@85004|Bifidobacteriales	201174|Actinobacteria	U	Drug resistance MFS transporter, drug H antiporter-2 family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,MFS_1
IOLKFBCL_01238	547043.BIFPSEUDO_04438	2.7e-17	73.6	29G83@1|root,3035W@2|Bacteria,2GQWW@201174|Actinobacteria,4D1G9@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01239	216816.GS08_04235	2.35e-151	426.0	COG1309@1|root,COG1309@2|Bacteria,2HZJX@201174|Actinobacteria,4D0QJ@85004|Bifidobacteriales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
IOLKFBCL_01240	326426.Bbr_0832	1.04e-273	752.0	COG2271@1|root,COG2271@2|Bacteria,2HZ9S@201174|Actinobacteria,4CZ4Z@85004|Bifidobacteriales	201174|Actinobacteria	G	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
IOLKFBCL_01241	216816.GS08_04225	2.19e-309	842.0	COG3550@1|root,COG3550@2|Bacteria,2IEMD@201174|Actinobacteria,4CZ2C@85004|Bifidobacteriales	201174|Actinobacteria	S	HipA-like C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	HipA_C
IOLKFBCL_01242	326426.Bbr_0829	5.09e-51	161.0	COG3077@1|root,COG3077@2|Bacteria,2IRS1@201174|Actinobacteria,4D1BV@85004|Bifidobacteriales	201174|Actinobacteria	L	RelB antitoxin	-	-	-	ko:K07473	-	-	-	-	ko00000,ko02048	-	-	-	RelB
IOLKFBCL_01243	216816.GS08_04215	1.92e-67	204.0	COG2337@1|root,COG2337@2|Bacteria,2IICB@201174|Actinobacteria,4D102@85004|Bifidobacteriales	201174|Actinobacteria	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
IOLKFBCL_01244	326426.Bbr_0827	2.26e-108	316.0	COG1917@1|root,COG1917@2|Bacteria,2IHSV@201174|Actinobacteria,4D0ZF@85004|Bifidobacteriales	201174|Actinobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
IOLKFBCL_01245	326426.Bbr_0826	6.44e-205	567.0	COG0030@1|root,COG0030@2|Bacteria,2I2II@201174|Actinobacteria,4CZIK@85004|Bifidobacteriales	201174|Actinobacteria	J	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
IOLKFBCL_01246	216816.GS08_04200	7.81e-79	236.0	COG3304@1|root,COG3304@2|Bacteria,2IKS5@201174|Actinobacteria,4D11K@85004|Bifidobacteriales	201174|Actinobacteria	S	Inner membrane component domain	yccF	-	-	-	-	-	-	-	-	-	-	-	YccF
IOLKFBCL_01247	216816.GS08_04195	3.18e-299	816.0	COG1510@1|root,COG3177@1|root,COG1510@2|Bacteria,COG3177@2|Bacteria,2HZGJ@201174|Actinobacteria,4D0D3@85004|Bifidobacteriales	201174|Actinobacteria	K	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
IOLKFBCL_01248	216816.GS08_00995	2.25e-31	120.0	COG3677@1|root,COG3677@2|Bacteria,2IEJD@201174|Actinobacteria,4CZTH@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
IOLKFBCL_01249	326426.Bbr_0822	0.0	1474.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,4CYXB@85004|Bifidobacteriales	201174|Actinobacteria	L	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
IOLKFBCL_01250	326426.Bbr_0821	4.79e-307	840.0	COG0534@1|root,COG0534@2|Bacteria,2GXXK@201174|Actinobacteria,4D04E@85004|Bifidobacteriales	201174|Actinobacteria	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
IOLKFBCL_01252	326426.Bbr_0820	2.31e-36	124.0	COG3743@1|root,COG3743@2|Bacteria	2|Bacteria	S	rRNA binding	-	-	-	ko:K02890,ko:K07343	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	TfoX_C
IOLKFBCL_01253	326426.Bbr_0819	2.63e-207	573.0	COG2207@1|root,COG3708@1|root,COG2207@2|Bacteria,COG3708@2|Bacteria,2GVAR@201174|Actinobacteria	201174|Actinobacteria	K	Arac family	tetD	-	-	ko:K13653	-	-	-	-	ko00000,ko03000	-	-	-	GyrI-like,HTH_18
IOLKFBCL_01254	326426.Bbr_0818	4.15e-258	708.0	COG0012@1|root,COG0012@2|Bacteria,2GIXI@201174|Actinobacteria,4CZBU@85004|Bifidobacteriales	201174|Actinobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
IOLKFBCL_01255	216816.GS08_04185	6.51e-181	505.0	COG0345@1|root,COG0345@2|Bacteria,2GJ7D@201174|Actinobacteria,4CZIV@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
IOLKFBCL_01256	216816.GS08_04180	0.0	901.0	COG0596@1|root,COG0596@2|Bacteria,2GK03@201174|Actinobacteria,4CZ9T@85004|Bifidobacteriales	201174|Actinobacteria	S	alpha/beta hydrolase fold	pip	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
IOLKFBCL_01258	216816.GS08_04175	0.0	1393.0	COG4585@1|root,COG4585@2|Bacteria,2GJEG@201174|Actinobacteria,4CZ1M@85004|Bifidobacteriales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
IOLKFBCL_01259	216816.GS08_04170	5.96e-182	509.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4CYQW@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
IOLKFBCL_01260	216816.GS08_04165	0.0	1521.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,2GJTZ@201174|Actinobacteria,4CZUR@85004|Bifidobacteriales	201174|Actinobacteria	MV	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
IOLKFBCL_01261	326426.Bbr_0808	8.85e-184	515.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4CZ04@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter, ATP-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IOLKFBCL_01262	216816.GS08_04155	9.49e-317	862.0	COG2873@1|root,COG2873@2|Bacteria,2I2EB@201174|Actinobacteria,4CZCT@85004|Bifidobacteriales	201174|Actinobacteria	E	Aminotransferase class-V	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
IOLKFBCL_01263	216816.GS08_04150	3.75e-209	578.0	COG2240@1|root,COG2240@2|Bacteria,2HS59@201174|Actinobacteria,4CYQC@85004|Bifidobacteriales	201174|Actinobacteria	H	Phosphomethylpyrimidine kinase	pdxY	-	2.7.1.35	ko:K00868	ko00750,ko01100,map00750,map01100	-	R00174,R01909,R02493	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	Phos_pyr_kin
IOLKFBCL_01264	216816.GS08_04145	3.62e-121	345.0	COG0792@1|root,COG0792@2|Bacteria,2IQ3X@201174|Actinobacteria,4D191@85004|Bifidobacteriales	201174|Actinobacteria	L	Belongs to the UPF0102 family	yraN	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
IOLKFBCL_01265	216816.GS08_04140	0.0	997.0	COG0606@1|root,COG0606@2|Bacteria,2GJIQ@201174|Actinobacteria,4CYUB@85004|Bifidobacteriales	201174|Actinobacteria	O	Magnesium chelatase, subunit ChlI C-terminal	comM	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
IOLKFBCL_01266	216816.GS08_04135	0.0	1061.0	COG0758@1|root,COG0758@2|Bacteria,2GKDA@201174|Actinobacteria,4CYVW@85004|Bifidobacteriales	201174|Actinobacteria	LU	DNA recombination-mediator protein A	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
IOLKFBCL_01267	216816.GS08_04130	0.0	1168.0	COG1053@1|root,COG1053@2|Bacteria,2GJ45@201174|Actinobacteria,4CYT5@85004|Bifidobacteriales	201174|Actinobacteria	C	Succinate dehydrogenase flavoprotein subunit	sdhA	GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363	1.3.5.1,1.3.5.4,1.4.3.16	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00115,M00149,M00173,M00374,M00376	R00357,R00481,R02164	RC00006,RC00045,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
IOLKFBCL_01268	216816.GS08_04125	7.19e-234	643.0	COG0479@1|root,COG0479@2|Bacteria,2GP9C@201174|Actinobacteria,4CZWJ@85004|Bifidobacteriales	201174|Actinobacteria	C	4Fe-4S dicluster domain	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_10,Fer4_8
IOLKFBCL_01269	216816.GS08_04120	2.45e-141	400.0	COG4122@1|root,COG4122@2|Bacteria,2HXV7@201174|Actinobacteria,4CZZN@85004|Bifidobacteriales	201174|Actinobacteria	S	O-methyltransferase	safC	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
IOLKFBCL_01270	216816.GS08_04115	9.06e-208	576.0	COG1611@1|root,COG1611@2|Bacteria,2GKJH@201174|Actinobacteria,4CZ8R@85004|Bifidobacteriales	201174|Actinobacteria	S	Belongs to the LOG family	fmt2	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
IOLKFBCL_01271	216816.GS08_04110	1.54e-306	840.0	COG3004@1|root,COG3004@2|Bacteria,2GKIK@201174|Actinobacteria,4CZES@85004|Bifidobacteriales	201174|Actinobacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
IOLKFBCL_01274	216816.GS08_04095	3.4e-311	850.0	COG1219@1|root,COG1219@2|Bacteria,2GJXQ@201174|Actinobacteria,4CYT6@85004|Bifidobacteriales	201174|Actinobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030312,GO:0030554,GO:0031333,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0044087,GO:0044238,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
IOLKFBCL_01275	216816.GS08_04090	1.81e-158	445.0	COG0740@1|root,COG0740@2|Bacteria,2GKNK@201174|Actinobacteria,4CZVF@85004|Bifidobacteriales	201174|Actinobacteria	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
IOLKFBCL_01276	216816.GS08_04085	4.2e-151	424.0	COG0740@1|root,COG0740@2|Bacteria,2GK5C@201174|Actinobacteria,4CYUU@85004|Bifidobacteriales	201174|Actinobacteria	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP1	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
IOLKFBCL_01277	216816.GS08_04080	2.82e-78	233.0	2A3Y6@1|root,30SGI@2|Bacteria,2IM76@201174|Actinobacteria,4D10Z@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01278	216816.GS08_04075	3e-299	822.0	COG0038@1|root,COG0038@2|Bacteria,2GPPN@201174|Actinobacteria,4CZPX@85004|Bifidobacteriales	201174|Actinobacteria	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	Voltage_CLC
IOLKFBCL_01279	216816.GS08_04070	4.94e-304	832.0	COG0544@1|root,COG0544@2|Bacteria,2GJIG@201174|Actinobacteria,4CZ6P@85004|Bifidobacteriales	201174|Actinobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
IOLKFBCL_01280	216816.GS08_04065	9.6e-317	862.0	COG0349@1|root,COG0349@2|Bacteria,2GKNM@201174|Actinobacteria,4CYUV@85004|Bifidobacteriales	201174|Actinobacteria	J	3'-5' exonuclease	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
IOLKFBCL_01281	216816.GS08_04060	5.5e-154	432.0	2B58P@1|root,31Y2Q@2|Bacteria,2HZMM@201174|Actinobacteria,4D0Y9@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3000)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3000
IOLKFBCL_01282	216816.GS08_04055	1.49e-221	609.0	COG1180@1|root,COG1180@2|Bacteria,2GN2B@201174|Actinobacteria,4CZ5Y@85004|Bifidobacteriales	201174|Actinobacteria	C	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
IOLKFBCL_01283	216816.GS08_04050	0.0	1599.0	COG1882@1|root,COG1882@2|Bacteria,2GTTT@201174|Actinobacteria,4CZ59@85004|Bifidobacteriales	201174|Actinobacteria	C	Pyruvate formate lyase-like	pflB	-	2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
IOLKFBCL_01284	216816.GS08_04045	9.66e-46	147.0	2EHMB@1|root,33BD3@2|Bacteria,2HZRX@201174|Actinobacteria,4D1G1@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01285	216816.GS08_04040	0.0	1098.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2GK2C@201174|Actinobacteria,4CZ14@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
IOLKFBCL_01286	216816.GS08_04035	1.64e-284	776.0	COG1473@1|root,COG1473@2|Bacteria,2GK05@201174|Actinobacteria,4CZC6@85004|Bifidobacteriales	201174|Actinobacteria	S	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
IOLKFBCL_01287	216816.GS08_04030	1.12e-145	412.0	COG2011@1|root,COG2011@2|Bacteria,2GY65@201174|Actinobacteria,4CZWG@85004|Bifidobacteriales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	metI	-	-	ko:K02072	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	BPD_transp_1
IOLKFBCL_01288	216816.GS08_04025	1.5e-276	758.0	COG1135@1|root,COG1135@2|Bacteria,2GJ9P@201174|Actinobacteria,4CZYI@85004|Bifidobacteriales	201174|Actinobacteria	P	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system	metN	-	-	ko:K02071	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	ABC_tran,NIL
IOLKFBCL_01289	216816.GS08_04020	1.22e-223	617.0	COG1464@1|root,COG1464@2|Bacteria,2GMNI@201174|Actinobacteria,4CZNB@85004|Bifidobacteriales	201174|Actinobacteria	P	NLPA lipoprotein	-	-	-	ko:K02073	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	Lipoprotein_9
IOLKFBCL_01290	216816.GS08_03995	0.0	1683.0	COG3957@1|root,COG3957@2|Bacteria,2GN27@201174|Actinobacteria,4CZT5@85004|Bifidobacteriales	201174|Actinobacteria	G	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase	xfp	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
IOLKFBCL_01291	216816.GS08_03990	0.0	1036.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,2GM09@201174|Actinobacteria,4CZC3@85004|Bifidobacteriales	201174|Actinobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
IOLKFBCL_01292	216816.GS08_03980	0.0	945.0	COG1835@1|root,COG1835@2|Bacteria,2GKI5@201174|Actinobacteria,4D0BY@85004|Bifidobacteriales	201174|Actinobacteria	I	Psort location CytoplasmicMembrane, score 9.99	yrhL	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
IOLKFBCL_01293	216816.GS08_03975	1.59e-244	671.0	COG0462@1|root,COG0462@2|Bacteria,2GJ9S@201174|Actinobacteria,4CYRD@85004|Bifidobacteriales	201174|Actinobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006015,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046390,GO:0046391,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901576	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
IOLKFBCL_01295	216816.GS08_03965	0.0	898.0	COG1207@1|root,COG1207@2|Bacteria,2GJS1@201174|Actinobacteria,4CZ4C@85004|Bifidobacteriales	201174|Actinobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030260,GO:0035635,GO:0040007,GO:0043167,GO:0043169,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3,NTP_transferase
IOLKFBCL_01296	216816.GS08_03960	5.2e-82	243.0	COG0799@1|root,COG0799@2|Bacteria,2IKZ3@201174|Actinobacteria,4D11U@85004|Bifidobacteriales	201174|Actinobacteria	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
IOLKFBCL_01297	216816.GS08_03955	2.28e-156	439.0	COG0406@1|root,COG0406@2|Bacteria,2GJYU@201174|Actinobacteria,4CYXK@85004|Bifidobacteriales	201174|Actinobacteria	G	Phosphoglycerate mutase family	gpmB	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0044237	3.1.3.85,5.4.2.11	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
IOLKFBCL_01300	216816.GS08_03940	0.0	1080.0	COG0280@1|root,COG0280@2|Bacteria,2GJ5U@201174|Actinobacteria,4CZE6@85004|Bifidobacteriales	201174|Actinobacteria	C	phosphate acetyltransferase	pta	GO:0005575,GO:0005576	2.3.1.8	ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,DRTGG,PTA_PTB
IOLKFBCL_01301	326426.Bbr_0771	2.87e-289	790.0	COG0282@1|root,COG0282@2|Bacteria,2GJAW@201174|Actinobacteria,4CZ7V@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0409	Acetate_kinase
IOLKFBCL_01302	216816.GS08_03930	6.91e-315	858.0	COG0128@1|root,COG0128@2|Bacteria,2GJKX@201174|Actinobacteria,4CZBG@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:0071944,GO:1901576	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
IOLKFBCL_01303	216816.GS08_03925	1.58e-249	688.0	2DSXT@1|root,32UTZ@2|Bacteria,2GKR7@201174|Actinobacteria,4CZBW@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
IOLKFBCL_01306	216816.GS08_03785	1.21e-18	80.5	COG1476@1|root,COG1476@2|Bacteria,2IGPZ@201174|Actinobacteria,4D0N7@85004|Bifidobacteriales	201174|Actinobacteria	K	Putative zinc ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,TipAS,Zn_ribbon_2
IOLKFBCL_01307	216816.GS08_03775	0.0	1459.0	COG1523@1|root,COG1523@2|Bacteria,2GJ00@201174|Actinobacteria,4CZGR@85004|Bifidobacteriales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 13 family	glgX	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
IOLKFBCL_01308	216816.GS08_03770	2.32e-161	451.0	COG0494@1|root,COG0494@2|Bacteria,2IIY0@201174|Actinobacteria,4D0P8@85004|Bifidobacteriales	201174|Actinobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
IOLKFBCL_01309	216816.GS08_03765	3.98e-228	627.0	COG0327@1|root,COG0327@2|Bacteria,2GKHZ@201174|Actinobacteria,4CYXC@85004|Bifidobacteriales	201174|Actinobacteria	L	NIF3 (NGG1p interacting factor 3)	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	-	-	-	-	-	-	-	-	-	NIF3
IOLKFBCL_01310	216816.GS08_03760	0.0	1855.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2GJY2@201174|Actinobacteria,4CYVK@85004|Bifidobacteriales	201174|Actinobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
IOLKFBCL_01311	216816.GS08_03755	3.04e-164	462.0	COG3707@1|root,COG3707@2|Bacteria,2GK7T@201174|Actinobacteria,4CYS7@85004|Bifidobacteriales	201174|Actinobacteria	T	Response regulator receiver domain protein	pdtaR	GO:0000160,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016020,GO:0023052,GO:0030312,GO:0035556,GO:0040007,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071944	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR,Response_reg
IOLKFBCL_01313	216816.GS08_03740	0.0	946.0	COG0469@1|root,COG0469@2|Bacteria,2GJY8@201174|Actinobacteria,4CZA8@85004|Bifidobacteriales	201174|Actinobacteria	G	Pyruvate kinase	pyk	GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
IOLKFBCL_01314	216816.GS08_03735	1.09e-227	628.0	COG0861@1|root,COG0861@2|Bacteria,2GIWU@201174|Actinobacteria,4CYW2@85004|Bifidobacteriales	201174|Actinobacteria	P	Integral membrane protein, TerC family	terC	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
IOLKFBCL_01315	216816.GS08_03730	0.0	1352.0	COG0556@1|root,COG0556@2|Bacteria,2GJ03@201174|Actinobacteria,4CZR0@85004|Bifidobacteriales	201174|Actinobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	GO:0002682,GO:0002684,GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
IOLKFBCL_01316	78344.BIGA_1187	9.26e-69	231.0	COG4585@1|root,COG4585@2|Bacteria,2I370@201174|Actinobacteria,4D0JE@85004|Bifidobacteriales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01317	78344.BIGA_1188	1.06e-80	247.0	COG2197@1|root,COG2197@2|Bacteria,2IAQ5@201174|Actinobacteria,4D0E3@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
IOLKFBCL_01318	78344.BIGA_1189	4.91e-177	525.0	COG4652@1|root,COG4652@2|Bacteria	2|Bacteria	-	-	XK27_10205	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	DUF1430
IOLKFBCL_01319	78344.BIGA_1190	4.34e-95	283.0	COG1136@1|root,COG1136@2|Bacteria,2IAY5@201174|Actinobacteria,4D0ZP@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IOLKFBCL_01320	547043.BIFPSEUDO_03478	1.79e-93	279.0	COG0237@1|root,COG0237@2|Bacteria,2GN96@201174|Actinobacteria,4D0PG@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE,GrpB
IOLKFBCL_01321	216816.GS08_03720	0.0	895.0	COG0539@1|root,COG0539@2|Bacteria,2GJAK@201174|Actinobacteria,4CZ6S@85004|Bifidobacteriales	201174|Actinobacteria	J	Ribosomal protein S1	rpsA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
IOLKFBCL_01322	216816.GS08_03715	9.81e-201	556.0	COG0190@1|root,COG0190@2|Bacteria,2GJZS@201174|Actinobacteria,4CZ53@85004|Bifidobacteriales	201174|Actinobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0040007,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
IOLKFBCL_01323	216816.GS08_03710	2.9e-258	711.0	COG0803@1|root,COG0803@2|Bacteria,2GM1K@201174|Actinobacteria,4CZ99@85004|Bifidobacteriales	201174|Actinobacteria	P	Zinc-uptake complex component A periplasmic	-	-	-	ko:K02077	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
IOLKFBCL_01324	216816.GS08_03705	5.11e-210	580.0	COG1121@1|root,COG1121@2|Bacteria,2GP3A@201174|Actinobacteria,4CZEV@85004|Bifidobacteriales	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02074	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC_tran
IOLKFBCL_01325	216816.GS08_03700	6.66e-176	493.0	COG1108@1|root,COG1108@2|Bacteria,2GJ7H@201174|Actinobacteria,4CYTG@85004|Bifidobacteriales	201174|Actinobacteria	U	ABC 3 transport family	znuB	-	-	ko:K02075	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC-3
IOLKFBCL_01326	216816.GS08_03695	9.43e-116	332.0	COG0245@1|root,COG0245@2|Bacteria,2II8H@201174|Actinobacteria,4D0X6@85004|Bifidobacteriales	201174|Actinobacteria	H	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
IOLKFBCL_01327	216816.GS08_03690	1.85e-131	374.0	COG1329@1|root,COG1329@2|Bacteria,2GKSU@201174|Actinobacteria,4CZXD@85004|Bifidobacteriales	201174|Actinobacteria	K	CarD-like/TRCF domain	carD	GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0040007,GO:0042594,GO:0044419,GO:0050896,GO:0051704,GO:0051716,GO:0071496	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
IOLKFBCL_01328	216816.GS08_03685	0.0	1543.0	COG0296@1|root,COG0296@2|Bacteria,2GJ5C@201174|Actinobacteria,4CZMD@85004|Bifidobacteriales	201174|Actinobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0055114,GO:0071704,GO:0071944,GO:1901576	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
IOLKFBCL_01329	216816.GS08_03680	8.63e-165	461.0	COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria,4CZS5@85004|Bifidobacteriales	201174|Actinobacteria	T	Response regulator receiver domain protein	cseB	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
IOLKFBCL_01330	216816.GS08_03675	2.36e-248	682.0	COG5002@1|root,COG5002@2|Bacteria,2GIX7@201174|Actinobacteria,4CZNA@85004|Bifidobacteriales	201174|Actinobacteria	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
IOLKFBCL_01331	216816.GS08_03670	2.22e-85	251.0	COG1974@1|root,COG1974@2|Bacteria,2GPJI@201174|Actinobacteria,4D0WP@85004|Bifidobacteriales	201174|Actinobacteria	KT	Peptidase S24-like	umuD	-	-	ko:K03503	-	-	-	-	ko00000,ko01000,ko01002,ko03400	-	-	-	Peptidase_S24
IOLKFBCL_01332	326426.Bbr_0743	2.41e-71	224.0	COG1040@1|root,COG1040@2|Bacteria,2I9PA@201174|Actinobacteria,4D11A@85004|Bifidobacteriales	201174|Actinobacteria	S	Phosphoribosyl transferase domain	pyrE_1	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
IOLKFBCL_01333	216816.GS08_03665	1.29e-193	536.0	COG0561@1|root,COG0561@2|Bacteria,2HZD0@201174|Actinobacteria,4CZ4N@85004|Bifidobacteriales	201174|Actinobacteria	T	Eukaryotic phosphomannomutase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3,PMM
IOLKFBCL_01334	326426.Bbr_0741	3.82e-95	277.0	COG3824@1|root,COG3824@2|Bacteria,2IS6W@201174|Actinobacteria,4D0YK@85004|Bifidobacteriales	201174|Actinobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
IOLKFBCL_01335	216816.GS08_03655	0.0	928.0	2DNQG@1|root,32YJZ@2|Bacteria,2I2FY@201174|Actinobacteria,4CZE9@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01336	216816.GS08_03650	0.0	1935.0	COG1216@1|root,COG5617@1|root,COG1216@2|Bacteria,COG5617@2|Bacteria,2I2FX@201174|Actinobacteria,4CYVM@85004|Bifidobacteriales	201174|Actinobacteria	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3
IOLKFBCL_01337	216816.GS08_03645	7.16e-75	223.0	2CC1Y@1|root,32RUK@2|Bacteria,2IQ4Q@201174|Actinobacteria,4D12I@85004|Bifidobacteriales	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB2	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
IOLKFBCL_01338	216816.GS08_03635	7.26e-207	580.0	COG1316@1|root,COG1316@2|Bacteria,2GJJJ@201174|Actinobacteria,4CYQY@85004|Bifidobacteriales	201174|Actinobacteria	K	Cell envelope-related transcriptional attenuator domain	lytR2	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
IOLKFBCL_01339	216816.GS08_03630	0.0	1095.0	COG1674@1|root,COG1674@2|Bacteria,2GJBR@201174|Actinobacteria,4CYU3@85004|Bifidobacteriales	201174|Actinobacteria	D	FtsK/SpoIIIE family	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_SpoIIIE,Yop-YscD_cpl
IOLKFBCL_01340	1437610.BREU_1071	3.32e-61	187.0	2DMIE@1|root,32RSG@2|Bacteria,2IQCG@201174|Actinobacteria,4D11W@85004|Bifidobacteriales	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB	GO:0000302,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0010035,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0015035,GO:0015036,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042221,GO:0042493,GO:0045892,GO:0045934,GO:0047134,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0060255,GO:0065007,GO:0071731,GO:0080090,GO:0097159,GO:0097366,GO:1901363,GO:1901698,GO:1901700,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
IOLKFBCL_01341	216816.GS08_03620	0.0	957.0	COG3920@1|root,COG3920@2|Bacteria,2GKMP@201174|Actinobacteria,4CYV1@85004|Bifidobacteriales	201174|Actinobacteria	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	pdtaS	GO:0000155,GO:0000160,GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005524,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	2.7.13.3	ko:K00936	-	M00839	-	-	ko00000,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,H_kinase_N,HisKA_2,PAS_4
IOLKFBCL_01342	216816.GS08_03600	7.85e-175	493.0	COG1272@1|root,COG1272@2|Bacteria,2GJGQ@201174|Actinobacteria,4CZGT@85004|Bifidobacteriales	201174|Actinobacteria	S	Haemolysin-III related	hlyIII	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
IOLKFBCL_01343	216816.GS08_03595	7.1e-106	306.0	COG0782@1|root,COG0782@2|Bacteria,2GNZV@201174|Actinobacteria,4D0QM@85004|Bifidobacteriales	201174|Actinobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0071944	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
IOLKFBCL_01344	216816.GS08_03590	5.53e-96	279.0	COG0545@1|root,COG0545@2|Bacteria,2GJK2@201174|Actinobacteria,4D0V6@85004|Bifidobacteriales	201174|Actinobacteria	G	Peptidyl-prolyl cis-trans	fkbP	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
IOLKFBCL_01345	216816.GS08_03585	0.0	960.0	COG1760@1|root,COG1760@2|Bacteria,2GJPA@201174|Actinobacteria,4CZ6I@85004|Bifidobacteriales	201174|Actinobacteria	E	Serine dehydratase alpha chain	sdaA	GO:0003674,GO:0003824,GO:0003941,GO:0016829,GO:0016840,GO:0016841	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha,SDH_beta
IOLKFBCL_01346	216816.GS08_03580	1.35e-120	345.0	2ASIR@1|root,31HZA@2|Bacteria,2IHD9@201174|Actinobacteria,4D0QP@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01348	216816.GS08_03570	9.72e-229	631.0	COG0248@1|root,COG0248@2|Bacteria,2GJBN@201174|Actinobacteria,4CZCS@85004|Bifidobacteriales	201174|Actinobacteria	FP	Ppx/GppA phosphatase family	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
IOLKFBCL_01349	216816.GS08_03565	1.61e-132	375.0	COG1507@1|root,COG1507@2|Bacteria,2I8CS@201174|Actinobacteria,4CZQX@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF501)	-	-	-	ko:K09009	-	-	-	-	ko00000	-	-	-	DUF501
IOLKFBCL_01350	216816.GS08_03560	9.56e-103	301.0	COG2919@1|root,COG2919@2|Bacteria,2IR5G@201174|Actinobacteria,4D0SS@85004|Bifidobacteriales	201174|Actinobacteria	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
IOLKFBCL_01351	216816.GS08_03555	3.54e-313	853.0	COG0148@1|root,COG0148@2|Bacteria,2GJAY@201174|Actinobacteria,4CYT3@85004|Bifidobacteriales	201174|Actinobacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
IOLKFBCL_01352	216816.GS08_03550	2.62e-220	607.0	COG0667@1|root,COG0667@2|Bacteria,2GJ6R@201174|Actinobacteria,4CZ9P@85004|Bifidobacteriales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
IOLKFBCL_01353	216816.GS08_03545	0.0	2298.0	COG1197@1|root,COG1197@2|Bacteria,2GJ42@201174|Actinobacteria,4CZ8X@85004|Bifidobacteriales	201174|Actinobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
IOLKFBCL_01354	216816.GS08_03540	4.23e-147	413.0	COG0193@1|root,COG0193@2|Bacteria,2GKCV@201174|Actinobacteria,4CZBE@85004|Bifidobacteriales	201174|Actinobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
IOLKFBCL_01355	216816.GS08_03535	2.11e-93	273.0	COG5573@1|root,COG5573@2|Bacteria,2INXT@201174|Actinobacteria,4D138@85004|Bifidobacteriales	201174|Actinobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
IOLKFBCL_01356	216816.GS08_03530	3.89e-62	191.0	2AYTE@1|root,31QYR@2|Bacteria,2ISWI@201174|Actinobacteria,4D19M@85004|Bifidobacteriales	201174|Actinobacteria	S	RelB antitoxin	-	-	-	-	-	-	-	-	-	-	-	-	RelB
IOLKFBCL_01357	216816.GS08_03520	3.22e-114	327.0	COG1247@1|root,COG1247@2|Bacteria,2HZCB@201174|Actinobacteria,4CZQI@85004|Bifidobacteriales	201174|Actinobacteria	M	Acetyltransferase (GNAT) domain	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_3,Acetyltransf_4
IOLKFBCL_01358	216816.GS08_03515	0.0	1960.0	COG1615@1|root,COG1615@2|Bacteria,2GMP3@201174|Actinobacteria,4CYW1@85004|Bifidobacteriales	201174|Actinobacteria	S	Uncharacterised protein family (UPF0182)	-	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
IOLKFBCL_01359	216816.GS08_03510	7.51e-265	728.0	COG1472@1|root,COG1472@2|Bacteria,2GM43@201174|Actinobacteria,4CZ6R@85004|Bifidobacteriales	201174|Actinobacteria	G	Glycosyl hydrolase family 3 N-terminal domain protein	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
IOLKFBCL_01360	216816.GS08_03505	5.62e-176	491.0	COG1057@1|root,COG1057@2|Bacteria,2GMFZ@201174|Actinobacteria,4CZ82@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
IOLKFBCL_01361	216816.GS08_03500	6.47e-130	369.0	2A13J@1|root,30P9F@2|Bacteria,2GKGD@201174|Actinobacteria,4D0QR@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01362	216816.GS08_03495	7.42e-294	804.0	COG0014@1|root,COG0014@2|Bacteria,2GISA@201174|Actinobacteria,4CZ2H@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016620,GO:0016903,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2427c	Aldedh
IOLKFBCL_01363	216816.GS08_03485	0.0	866.0	COG0112@1|root,COG0112@2|Bacteria,2GK7U@201174|Actinobacteria,4CZBV@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	GO:0001505,GO:0003674,GO:0003824,GO:0004372,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006544,GO:0006563,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009069,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016742,GO:0017144,GO:0019752,GO:0019842,GO:0020012,GO:0030170,GO:0030312,GO:0030682,GO:0036094,GO:0042133,GO:0042783,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044464,GO:0046983,GO:0048037,GO:0050662,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0065008,GO:0070279,GO:0071704,GO:0071944,GO:0075136,GO:0097159,GO:1901363,GO:1901564,GO:1901605	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
IOLKFBCL_01364	216816.GS08_03480	0.0	973.0	COG0498@1|root,COG0498@2|Bacteria,2GIRY@201174|Actinobacteria,4CYS0@85004|Bifidobacteriales	201174|Actinobacteria	E	Threonine synthase N terminus	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_synth_N
IOLKFBCL_01365	216816.GS08_03475	1.36e-250	690.0	COG4194@1|root,COG4194@2|Bacteria,2IBNS@201174|Actinobacteria,4CZJU@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF1648)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1648
IOLKFBCL_01366	216816.GS08_03470	2e-98	286.0	COG1725@1|root,COG1725@2|Bacteria,2IMER@201174|Actinobacteria,4D16Q@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
IOLKFBCL_01367	762211.BSTEL_0364	8.18e-293	815.0	COG2865@1|root,COG2865@2|Bacteria,2GZ30@201174|Actinobacteria,4CYSX@85004|Bifidobacteriales	201174|Actinobacteria	K	Putative ATP-dependent DNA helicase recG C-terminal	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4,HTH_24,HTH_5,HTH_IclR,TrmB
IOLKFBCL_01368	216816.GS08_03455	1.24e-52	166.0	COG0474@1|root,COG0474@2|Bacteria	2|Bacteria	P	ATPase, P-type transporting, HAD superfamily, subfamily IC	pacL2	-	3.6.3.8	ko:K01537,ko:K12955	-	-	-	-	ko00000,ko01000	3.A.3.2,3.A.3.24	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
IOLKFBCL_01369	216816.GS08_03450	2.8e-91	271.0	2B3RX@1|root,31PYJ@2|Bacteria,2IRDS@201174|Actinobacteria,4D16Y@85004|Bifidobacteriales	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_5
IOLKFBCL_01370	326426.Bbr_0713	1.94e-155	437.0	2ARYF@1|root,31HAF@2|Bacteria,2IK3T@201174|Actinobacteria,4D0YH@85004|Bifidobacteriales	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_5
IOLKFBCL_01371	326426.Bbr_0712	1.32e-222	613.0	COG1131@1|root,COG1131@2|Bacteria,2GRE8@201174|Actinobacteria,4CZBH@85004|Bifidobacteriales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IOLKFBCL_01372	326426.Bbr_0711	3.46e-78	233.0	COG1725@1|root,COG1725@2|Bacteria,2IQEW@201174|Actinobacteria,4D152@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
IOLKFBCL_01373	471856.Jden_0092	1.27e-75	248.0	COG0477@1|root,COG2814@2|Bacteria,2GJPT@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
IOLKFBCL_01375	216816.GS08_03430	1.51e-148	418.0	COG0637@1|root,COG0637@2|Bacteria,2I362@201174|Actinobacteria,4CZ8D@85004|Bifidobacteriales	201174|Actinobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
IOLKFBCL_01376	216816.GS08_03425	0.0	1070.0	COG0497@1|root,COG0497@2|Bacteria,2GIVG@201174|Actinobacteria,4CYYF@85004|Bifidobacteriales	201174|Actinobacteria	L	May be involved in recombinational repair of damaged DNA	recN	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
IOLKFBCL_01377	216816.GS08_03420	8.22e-246	675.0	COG0061@1|root,COG0061@2|Bacteria,2GKM2@201174|Actinobacteria,4CYZ0@85004|Bifidobacteriales	201174|Actinobacteria	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006797,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
IOLKFBCL_01378	216816.GS08_03405	1.12e-125	361.0	2B0CX@1|root,31SQ3@2|Bacteria,2GR13@201174|Actinobacteria,4D1JN@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01379	216816.GS08_03400	2.37e-175	489.0	COG1189@1|root,COG1189@2|Bacteria,2GJVT@201174|Actinobacteria,4CZSS@85004|Bifidobacteriales	201174|Actinobacteria	J	Ribosomal RNA large subunit methyltransferase J	tlyA	GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
IOLKFBCL_01381	216816.GS08_03390	1.22e-249	685.0	COG0647@1|root,COG0647@2|Bacteria,2GK7V@201174|Actinobacteria,4CZ1Z@85004|Bifidobacteriales	201174|Actinobacteria	G	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_6,Hydrolase_like
IOLKFBCL_01382	216816.GS08_03385	6.78e-227	649.0	COG0457@1|root,COG0457@2|Bacteria,2GKX5@201174|Actinobacteria,4CYXN@85004|Bifidobacteriales	201174|Actinobacteria	L	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
IOLKFBCL_01383	216816.GS08_03380	0.0	875.0	COG0162@1|root,COG0162@2|Bacteria,2GJPR@201174|Actinobacteria,4CZKG@85004|Bifidobacteriales	201174|Actinobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0030312,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
IOLKFBCL_01384	216816.GS08_03375	1.67e-174	487.0	COG4905@1|root,COG4905@2|Bacteria,2IA3M@201174|Actinobacteria,4CZY7@85004|Bifidobacteriales	201174|Actinobacteria	S	Putative ABC-transporter type IV	-	-	-	-	-	-	-	-	-	-	-	-	ABC_trans_CmpB
IOLKFBCL_01385	216816.GS08_03370	1.24e-126	360.0	COG1418@1|root,COG1418@2|Bacteria,2IFXP@201174|Actinobacteria,4D0P2@85004|Bifidobacteriales	201174|Actinobacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
IOLKFBCL_01386	326426.Bbr_0696	1.76e-73	221.0	COG0607@1|root,COG0607@2|Bacteria,2ISA2@201174|Actinobacteria,4D2SX@85004|Bifidobacteriales	201174|Actinobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
IOLKFBCL_01387	216816.GS08_03360	1.19e-190	529.0	COG0476@1|root,COG0476@2|Bacteria,2GJB6@201174|Actinobacteria,4D06G@85004|Bifidobacteriales	201174|Actinobacteria	H	ThiF family	thiF	-	2.7.7.73,2.7.7.80,2.8.1.11	ko:K03148,ko:K21147	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
IOLKFBCL_01388	326426.Bbr_0694	1.19e-200	556.0	COG2022@1|root,COG2022@2|Bacteria,2GM62@201174|Actinobacteria,4CZ4A@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG,ThiS
IOLKFBCL_01389	216816.GS08_03350	5.04e-39	129.0	COG2104@1|root,COG2104@2|Bacteria,2GSKM@201174|Actinobacteria,4D1GS@85004|Bifidobacteriales	201174|Actinobacteria	H	ThiS family	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
IOLKFBCL_01390	216816.GS08_03345	0.0	963.0	COG0165@1|root,COG0165@2|Bacteria,2GJ2A@201174|Actinobacteria,4CZ50@85004|Bifidobacteriales	201174|Actinobacteria	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0030312,GO:0040007,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
IOLKFBCL_01391	216816.GS08_03340	4.9e-303	825.0	COG0137@1|root,COG0137@2|Bacteria,2GK96@201174|Actinobacteria,4CZ2R@85004|Bifidobacteriales	201174|Actinobacteria	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0071944,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iNJ661.Rv1658	Arginosuc_synth
IOLKFBCL_01392	216816.GS08_03335	4.34e-110	317.0	COG1438@1|root,COG1438@2|Bacteria,2GKA5@201174|Actinobacteria,4D0VM@85004|Bifidobacteriales	201174|Actinobacteria	K	Regulates arginine biosynthesis genes	argR	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
IOLKFBCL_01393	216816.GS08_03330	7.19e-234	643.0	COG0078@1|root,COG0078@2|Bacteria,2GJ6H@201174|Actinobacteria,4CZGN@85004|Bifidobacteriales	201174|Actinobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0040007,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
IOLKFBCL_01394	216816.GS08_03325	9.37e-313	852.0	COG4992@1|root,COG4992@2|Bacteria,2GKE9@201174|Actinobacteria,4CZGW@85004|Bifidobacteriales	201174|Actinobacteria	E	Aminotransferase class-III	argD	GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0008150,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
IOLKFBCL_01395	216816.GS08_03320	3.68e-212	587.0	COG0548@1|root,COG0548@2|Bacteria,2GKDS@201174|Actinobacteria,4CYYX@85004|Bifidobacteriales	201174|Actinobacteria	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0030312,GO:0031406,GO:0034618,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
IOLKFBCL_01396	216816.GS08_03315	7.94e-271	742.0	COG1364@1|root,COG1364@2|Bacteria,2GIW0@201174|Actinobacteria,4CZQQ@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
IOLKFBCL_01397	216816.GS08_03310	1.02e-257	707.0	COG0002@1|root,COG0002@2|Bacteria,2GKQK@201174|Actinobacteria,4CZNC@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	GO:0000166,GO:0003674,GO:0005488,GO:0008150,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0048037,GO:0050661,GO:0050662,GO:0070401,GO:0097159,GO:1901265,GO:1901363	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
IOLKFBCL_01398	216816.GS08_03305	3.07e-143	406.0	2AHAX@1|root,317M8@2|Bacteria,2IPJ5@201174|Actinobacteria,4D11M@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01399	216816.GS08_03300	0.0	1739.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,2GMFD@201174|Actinobacteria,4CYUM@85004|Bifidobacteriales	201174|Actinobacteria	J	Phenylalanyl-tRNA synthetase beta	pheT	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
IOLKFBCL_01400	216816.GS08_03295	1.83e-258	707.0	COG0016@1|root,COG0016@2|Bacteria,2GJGG@201174|Actinobacteria,4CZ78@85004|Bifidobacteriales	201174|Actinobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
IOLKFBCL_01401	216816.GS08_03290	9.21e-211	582.0	COG0566@1|root,COG0566@2|Bacteria,2GJI6@201174|Actinobacteria,4CYZQ@85004|Bifidobacteriales	201174|Actinobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	tsnR	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
IOLKFBCL_01402	216816.GS08_03285	9.39e-191	530.0	COG0619@1|root,COG0619@2|Bacteria,2IDC9@201174|Actinobacteria,4CZM8@85004|Bifidobacteriales	201174|Actinobacteria	P	Cobalt transport protein	ykoC	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
IOLKFBCL_01403	216816.GS08_03280	0.0	943.0	COG1122@1|root,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria,4CYZ6@85004|Bifidobacteriales	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	ykoD	-	-	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran,CbiQ
IOLKFBCL_01404	216816.GS08_03275	7.57e-141	397.0	COG4721@1|root,COG4721@2|Bacteria,2IDAN@201174|Actinobacteria,4D00D@85004|Bifidobacteriales	201174|Actinobacteria	S	ABC-type cobalt transport system, permease component	ykoE	-	-	ko:K16925	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.30	-	-	ABC_cobalt
IOLKFBCL_01405	216816.GS08_03270	0.0	898.0	COG0624@1|root,COG0624@2|Bacteria,2GM84@201174|Actinobacteria,4CYZT@85004|Bifidobacteriales	201174|Actinobacteria	E	Peptidase dimerisation domain	argE	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
IOLKFBCL_01406	216816.GS08_03265	5.45e-138	391.0	2AN86@1|root,31D67@2|Bacteria,2HWWU@201174|Actinobacteria,4CZZS@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3043)	-	GO:0008150,GO:0009605,GO:0009607,GO:0020012,GO:0030682,GO:0042783,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136	-	-	-	-	-	-	-	-	-	-	DUF3043
IOLKFBCL_01407	216816.GS08_03260	0.0	957.0	COG1249@1|root,COG1249@2|Bacteria,2GIXY@201174|Actinobacteria,4CZEI@85004|Bifidobacteriales	201174|Actinobacteria	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
IOLKFBCL_01408	216816.GS08_03255	7.35e-176	491.0	2AUFS@1|root,2ZBYU@2|Bacteria,2I87Z@201174|Actinobacteria,4CYT8@85004|Bifidobacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4191)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4191
IOLKFBCL_01409	216816.GS08_03250	0.0	968.0	COG0174@1|root,COG0174@2|Bacteria,2GMN1@201174|Actinobacteria,4CZNK@85004|Bifidobacteriales	201174|Actinobacteria	E	glutamine synthetase	glnA	GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
IOLKFBCL_01410	216816.GS08_03245	4.08e-107	309.0	COG3250@1|root,COG3250@2|Bacteria,2GMAT@201174|Actinobacteria,4CZ6B@85004|Bifidobacteriales	201174|Actinobacteria	G	Glycosyl hydrolases family 2, TIM barrel domain	-	-	3.2.1.23,3.2.1.31	ko:K01190,ko:K01195	ko00040,ko00052,ko00511,ko00531,ko00600,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00052,map00511,map00531,map00600,map00860,map00944,map00983,map01100,map01110,map04142	M00014,M00076,M00077,M00078,M00129	R01105,R01478,R01678,R03355,R04783,R04979,R06114,R07818,R08127,R08260,R10830	RC00049,RC00055,RC00171,RC00452,RC00529,RC00530,RC00714,RC01251	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
IOLKFBCL_01411	216816.GS08_03240	2.57e-234	647.0	COG0679@1|root,COG0679@2|Bacteria,2GMWC@201174|Actinobacteria,4D0CA@85004|Bifidobacteriales	201174|Actinobacteria	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
IOLKFBCL_01412	216816.GS08_03230	9.16e-99	291.0	COG0110@1|root,COG0110@2|Bacteria,2GNUB@201174|Actinobacteria,4CZ5H@85004|Bifidobacteriales	201174|Actinobacteria	S	Maltose acetyltransferase	-	-	2.3.1.18,2.3.1.79	ko:K00633,ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2,Mac
IOLKFBCL_01413	158787.BSCA_2016	3.36e-108	313.0	COG1695@1|root,COG1695@2|Bacteria,2I8K2@201174|Actinobacteria,4D0KJ@85004|Bifidobacteriales	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
IOLKFBCL_01415	216816.GS08_03225	1.7e-150	424.0	COG2231@1|root,COG2231@2|Bacteria,2ICDU@201174|Actinobacteria,4D03Q@85004|Bifidobacteriales	201174|Actinobacteria	L	endonuclease III	-	-	-	ko:K07457	-	-	-	-	ko00000	-	-	-	HhH-GPD
IOLKFBCL_01416	216816.GS08_03220	8.96e-308	841.0	COG0534@1|root,COG0534@2|Bacteria,2GXXK@201174|Actinobacteria,4CZU6@85004|Bifidobacteriales	201174|Actinobacteria	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
IOLKFBCL_01417	216816.GS08_03215	0.0	1622.0	COG0178@1|root,COG0178@2|Bacteria,2GNMW@201174|Actinobacteria,4CZ5X@85004|Bifidobacteriales	201174|Actinobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate	uvrA3	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
IOLKFBCL_01418	216816.GS08_03205	0.0	1099.0	COG2959@1|root,COG2959@2|Bacteria,2I2HI@201174|Actinobacteria,4CYVN@85004|Bifidobacteriales	201174|Actinobacteria	H	Protein of unknown function (DUF4012)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4012
IOLKFBCL_01419	356829.BITS_1851	2.79e-38	144.0	2BGGQ@1|root,32AER@2|Bacteria,2GPXC@201174|Actinobacteria,4D1AU@85004|Bifidobacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4913)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4913
IOLKFBCL_01420	1437609.BCAL_0105	1.04e-92	280.0	COG1484@1|root,COG1484@2|Bacteria,2H714@201174|Actinobacteria,4CZRM@85004|Bifidobacteriales	201174|Actinobacteria	L	IstB-like ATP binding protein	istB	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
IOLKFBCL_01421	326426.Bbr_0152	1.73e-60	200.0	COG4584@1|root,COG4584@2|Bacteria,2IBDV@201174|Actinobacteria,4CZS6@85004|Bifidobacteriales	201174|Actinobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve
IOLKFBCL_01422	465515.Mlut_06470	5.34e-76	241.0	COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria,1W7QH@1268|Micrococcaceae	201174|Actinobacteria	L	PFAM Transposase, Mutator family	-	-	-	ko:K07493	-	-	-	-	ko00000	-	-	-	Transposase_mut
IOLKFBCL_01424	216816.GS08_09310	3.58e-198	548.0	COG1131@1|root,COG1131@2|Bacteria,2GKWE@201174|Actinobacteria,4CZUM@85004|Bifidobacteriales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
IOLKFBCL_01425	216816.GS08_09305	6.6e-241	662.0	COG2274@1|root,COG2274@2|Bacteria,2GNB5@201174|Actinobacteria,4D1BI@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran,Peptidase_C39
IOLKFBCL_01426	216816.GS08_09300	1.44e-56	176.0	COG0184@1|root,COG0184@2|Bacteria,2IQA0@201174|Actinobacteria,4D10E@85004|Bifidobacteriales	201174|Actinobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
IOLKFBCL_01427	216816.GS08_09295	0.0	1546.0	COG1185@1|root,COG1185@2|Bacteria,2GIT2@201174|Actinobacteria,4CYSW@85004|Bifidobacteriales	201174|Actinobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
IOLKFBCL_01428	216816.GS08_09290	5.25e-313	855.0	COG2252@1|root,COG2252@2|Bacteria,2GKYD@201174|Actinobacteria,4CZHD@85004|Bifidobacteriales	201174|Actinobacteria	S	Permease family	-	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
IOLKFBCL_01429	216816.GS08_09285	1.65e-180	504.0	COG1073@1|root,COG1073@2|Bacteria,2HZF3@201174|Actinobacteria,4D06X@85004|Bifidobacteriales	201174|Actinobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01430	216816.GS08_09280	2.41e-113	326.0	COG0244@1|root,COG0244@2|Bacteria,2GM0V@201174|Actinobacteria,4CZFP@85004|Bifidobacteriales	201174|Actinobacteria	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
IOLKFBCL_01431	216816.GS08_09275	6.07e-64	197.0	COG0222@1|root,COG0222@2|Bacteria,2IKNW@201174|Actinobacteria,4D0W2@85004|Bifidobacteriales	201174|Actinobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
IOLKFBCL_01432	216816.GS08_09270	6.37e-249	693.0	COG1716@1|root,COG1716@2|Bacteria,2GIT6@201174|Actinobacteria,4CYX9@85004|Bifidobacteriales	201174|Actinobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
IOLKFBCL_01433	216816.GS08_09265	0.0	2298.0	COG1112@1|root,COG1112@2|Bacteria,2GKJW@201174|Actinobacteria,4CYY9@85004|Bifidobacteriales	201174|Actinobacteria	L	Superfamily I DNA and RNA helicases and helicase subunits	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF4011
IOLKFBCL_01434	216816.GS08_09260	2.09e-41	135.0	2B18D@1|root,31TNU@2|Bacteria,2GSR6@201174|Actinobacteria,4D1ET@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01435	216816.GS08_09255	5.03e-121	347.0	COG1261@1|root,COG1261@2|Bacteria,2IIYF@201174|Actinobacteria,4D0YD@85004|Bifidobacteriales	201174|Actinobacteria	NO	SAF	-	-	-	-	-	-	-	-	-	-	-	-	ChapFlgA,SAF
IOLKFBCL_01436	216816.GS08_09250	2.17e-43	140.0	COG2331@1|root,COG2331@2|Bacteria,2IQHE@201174|Actinobacteria,4D1ES@85004|Bifidobacteriales	201174|Actinobacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
IOLKFBCL_01437	216816.GS08_09245	4.56e-166	465.0	COG0212@1|root,COG0212@2|Bacteria,2IKWR@201174|Actinobacteria,4D12B@85004|Bifidobacteriales	201174|Actinobacteria	H	5-formyltetrahydrofolate cyclo-ligase family	ygfA	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
IOLKFBCL_01438	216816.GS08_09240	2.42e-166	464.0	COG1670@1|root,COG1670@2|Bacteria,2HAFI@201174|Actinobacteria,4CZRR@85004|Bifidobacteriales	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	rimJ	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
IOLKFBCL_01439	216816.GS08_09235	6.02e-277	765.0	2E03N@1|root,32VSG@2|Bacteria,2GQE4@201174|Actinobacteria,4CYUX@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01440	216816.GS08_09230	6.02e-64	195.0	COG0234@1|root,COG0234@2|Bacteria,2IKTH@201174|Actinobacteria,4D101@85004|Bifidobacteriales	201174|Actinobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
IOLKFBCL_01441	1437610.BREU_0582	2.94e-51	174.0	COG0626@1|root,COG0626@2|Bacteria,2GNZH@201174|Actinobacteria,4D04I@85004|Bifidobacteriales	201174|Actinobacteria	E	Cys/Met metabolism PLP-dependent enzyme	megL	-	4.4.1.11	ko:K01761	ko00270,ko00450,map00270,map00450	-	R00654,R04770	RC00196,RC00348,RC01209,RC01210	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
IOLKFBCL_01445	1437609.BCAL_1264	1.03e-34	118.0	COG0267@1|root,COG0267@2|Bacteria,2GQFG@201174|Actinobacteria,4D1EA@85004|Bifidobacteriales	201174|Actinobacteria	J	Ribosomal protein L33	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
IOLKFBCL_01446	216816.GS08_09195	1.17e-287	786.0	COG0812@1|root,COG0812@2|Bacteria,2GIV2@201174|Actinobacteria,4CZSJ@85004|Bifidobacteriales	201174|Actinobacteria	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
IOLKFBCL_01447	216816.GS08_09190	0.0	956.0	COG0531@1|root,COG0531@2|Bacteria,2GJ75@201174|Actinobacteria,4CYZA@85004|Bifidobacteriales	201174|Actinobacteria	E	aromatic amino acid transport protein AroP K03293	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
IOLKFBCL_01448	216816.GS08_09185	1.57e-79	235.0	COG1146@1|root,COG1146@2|Bacteria,2IKVN@201174|Actinobacteria,4D11B@85004|Bifidobacteriales	201174|Actinobacteria	C	4Fe-4S binding domain	fdxA	GO:0001666,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0009628,GO:0036293,GO:0043207,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0070482,GO:0075136	-	ko:K05524	-	-	-	-	ko00000	-	-	-	Fer4
IOLKFBCL_01449	216816.GS08_09180	4.38e-285	780.0	COG0436@1|root,COG0436@2|Bacteria,2GJMI@201174|Actinobacteria,4CZ91@85004|Bifidobacteriales	201174|Actinobacteria	E	Aminotransferase class I and II	dapC	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
IOLKFBCL_01450	216816.GS08_09175	3.34e-298	816.0	COG0389@1|root,COG0389@2|Bacteria,2GKBI@201174|Actinobacteria,4CZHT@85004|Bifidobacteriales	201174|Actinobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	HHH_5,IMS,IMS_C,IMS_HHH
IOLKFBCL_01453	216816.GS08_09155	3.58e-238	655.0	COG0111@1|root,COG0111@2|Bacteria,2GKTT@201174|Actinobacteria,4CZRS@85004|Bifidobacteriales	201174|Actinobacteria	EH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	pdxB	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
IOLKFBCL_01454	216816.GS08_09150	5.2e-139	394.0	COG1739@1|root,COG1739@2|Bacteria,2GMM4@201174|Actinobacteria,4CZH8@85004|Bifidobacteriales	201174|Actinobacteria	S	Uncharacterized protein family UPF0029	yigZ	-	-	-	-	-	-	-	-	-	-	-	DUF1949,UPF0029
IOLKFBCL_01455	216816.GS08_09145	3.49e-147	417.0	2BMRI@1|root,32GAY@2|Bacteria,2GMIA@201174|Actinobacteria,4CZFZ@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	LRV
IOLKFBCL_01456	216816.GS08_09140	0.0	1437.0	COG1640@1|root,COG1640@2|Bacteria,2GM5Z@201174|Actinobacteria,4CZC7@85004|Bifidobacteriales	201174|Actinobacteria	G	4-alpha-glucanotransferase	malQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
IOLKFBCL_01457	216816.GS08_09135	3.75e-103	298.0	COG0102@1|root,COG0102@2|Bacteria,2IFG1@201174|Actinobacteria,4D0PV@85004|Bifidobacteriales	201174|Actinobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
IOLKFBCL_01458	216816.GS08_09130	9.6e-106	306.0	COG0103@1|root,COG0103@2|Bacteria,2GNDY@201174|Actinobacteria,4CZ9Y@85004|Bifidobacteriales	201174|Actinobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
IOLKFBCL_01459	216816.GS08_09125	0.0	1715.0	COG1523@1|root,COG1523@2|Bacteria,2GJ00@201174|Actinobacteria,4CYZ1@85004|Bifidobacteriales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 13 family	glgX	-	3.2.1.196,3.2.1.68	ko:K01214,ko:K02438	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02111,R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
IOLKFBCL_01460	1437609.BCAL_1294	1.53e-221	613.0	COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria,4D04X@85004|Bifidobacteriales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	1.1.1.1,1.1.1.287,1.6.5.5	ko:K00001,ko:K00344,ko:K17818	ko00010,ko00040,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R07143,R07144,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00102,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
IOLKFBCL_01461	78346.BRUM_0709	1.1e-283	780.0	COG0477@1|root,COG2814@2|Bacteria,2GPRH@201174|Actinobacteria,4D048@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	csbX	-	-	-	-	-	-	-	-	-	-	-	MFS_1
IOLKFBCL_01462	158787.BSCA_1133	9.69e-87	255.0	COG0346@1|root,COG0346@2|Bacteria,2IHBC@201174|Actinobacteria,4D0P3@85004|Bifidobacteriales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
IOLKFBCL_01463	762211.BSTEL_0575	1.9e-275	757.0	COG0477@1|root,COG2814@2|Bacteria,2GPRH@201174|Actinobacteria,4D048@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	csbX	-	-	-	-	-	-	-	-	-	-	-	MFS_1
IOLKFBCL_01464	762211.BSTEL_0574	1.31e-244	672.0	COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria,4D04X@85004|Bifidobacteriales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	1.1.1.9	ko:K05351	ko00040,ko01100,map00040,map01100	M00014	R01896	RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
IOLKFBCL_01465	762211.BSTEL_0573	3.56e-174	490.0	COG2207@1|root,COG2207@2|Bacteria,2HZE7@201174|Actinobacteria,4D00U@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
IOLKFBCL_01467	216816.GS08_09120	6.5e-280	765.0	COG1940@1|root,COG1940@2|Bacteria,2I7R8@201174|Actinobacteria,4CZZ7@85004|Bifidobacteriales	201174|Actinobacteria	GK	transcriptional repressor of nag (N-acetylglucosamine) operon K02565	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,MarR,ROK
IOLKFBCL_01468	216816.GS08_09115	0.0	1784.0	COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,2GJI2@201174|Actinobacteria,4CZ8F@85004|Bifidobacteriales	201174|Actinobacteria	C	belongs to the iron- containing alcohol dehydrogenase family	adhE	-	1.1.1.1,1.2.1.10,1.2.1.81	ko:K04072,ko:K15515	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	-	R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927	RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195	ko00000,ko00001,ko01000	-	-	-	Aldedh,Fe-ADH
IOLKFBCL_01469	216816.GS08_09110	1.4e-190	533.0	28NT3@1|root,2ZBRV@2|Bacteria,2IIC3@201174|Actinobacteria,4D0MQ@85004|Bifidobacteriales	201174|Actinobacteria	S	YwiC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YwiC
IOLKFBCL_01470	1437600.JDUI01000009_gene364	9.35e-68	205.0	COG0051@1|root,COG0051@2|Bacteria,2IHRA@201174|Actinobacteria,4D0UT@85004|Bifidobacteriales	201174|Actinobacteria	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
IOLKFBCL_01471	216816.GS08_09095	1.57e-149	421.0	COG0087@1|root,COG0087@2|Bacteria,2GJXT@201174|Actinobacteria,4CYQD@85004|Bifidobacteriales	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
IOLKFBCL_01472	216816.GS08_09090	1.97e-150	423.0	COG0088@1|root,COG0088@2|Bacteria,2GJYJ@201174|Actinobacteria,4CZSA@85004|Bifidobacteriales	201174|Actinobacteria	J	Forms part of the polypeptide exit tunnel	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
IOLKFBCL_01473	158787.BSCA_1142	8.86e-62	189.0	COG0089@1|root,COG0089@2|Bacteria,2IQ7V@201174|Actinobacteria,4D11N@85004|Bifidobacteriales	201174|Actinobacteria	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
IOLKFBCL_01474	216816.GS08_09080	1.34e-195	542.0	COG0090@1|root,COG0090@2|Bacteria,2GK7R@201174|Actinobacteria,4CZ5U@85004|Bifidobacteriales	201174|Actinobacteria	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
IOLKFBCL_01475	1437608.BBIA_2303	1.4e-62	191.0	COG0185@1|root,COG0185@2|Bacteria,2IKMS@201174|Actinobacteria,4D105@85004|Bifidobacteriales	201174|Actinobacteria	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016020,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0071944,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
IOLKFBCL_01476	216816.GS08_09070	1.55e-74	223.0	COG0091@1|root,COG0091@2|Bacteria,2IM3J@201174|Actinobacteria,4D0UZ@85004|Bifidobacteriales	201174|Actinobacteria	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
IOLKFBCL_01477	216816.GS08_09065	1.32e-161	456.0	COG0092@1|root,COG0092@2|Bacteria,2GKF1@201174|Actinobacteria,4CYQN@85004|Bifidobacteriales	201174|Actinobacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
IOLKFBCL_01478	216816.GS08_09060	3.85e-98	285.0	COG0197@1|root,COG0197@2|Bacteria,2IFEI@201174|Actinobacteria,4D0Q8@85004|Bifidobacteriales	201174|Actinobacteria	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
IOLKFBCL_01479	216816.GS08_09055	1.97e-49	157.0	COG0255@1|root,COG0255@2|Bacteria,2IQ6V@201174|Actinobacteria,4D181@85004|Bifidobacteriales	201174|Actinobacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
IOLKFBCL_01480	216816.GS08_09050	1.11e-54	171.0	COG0186@1|root,COG0186@2|Bacteria,2IQ68@201174|Actinobacteria,4D10N@85004|Bifidobacteriales	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
IOLKFBCL_01481	216816.GS08_09045	2.55e-79	236.0	COG0093@1|root,COG0093@2|Bacteria,2IHNX@201174|Actinobacteria,4D0VI@85004|Bifidobacteriales	201174|Actinobacteria	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071944,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
IOLKFBCL_01482	216816.GS08_09040	1.09e-68	208.0	COG0198@1|root,COG0198@2|Bacteria,2IKP2@201174|Actinobacteria,4D10I@85004|Bifidobacteriales	201174|Actinobacteria	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
IOLKFBCL_01483	216816.GS08_09035	2.77e-134	380.0	COG0094@1|root,COG0094@2|Bacteria,2GJW7@201174|Actinobacteria,4CZCA@85004|Bifidobacteriales	201174|Actinobacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
IOLKFBCL_01484	1437609.BCAL_1317	7.06e-40	131.0	COG0199@1|root,COG0199@2|Bacteria,2IQ8R@201174|Actinobacteria,4D177@85004|Bifidobacteriales	201174|Actinobacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
IOLKFBCL_01485	1437610.BREU_0623	3.17e-90	264.0	COG0096@1|root,COG0096@2|Bacteria,2IHQZ@201174|Actinobacteria,4D0P6@85004|Bifidobacteriales	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
IOLKFBCL_01486	216816.GS08_09020	7.72e-122	348.0	COG0097@1|root,COG0097@2|Bacteria,2GK35@201174|Actinobacteria,4CYQV@85004|Bifidobacteriales	201174|Actinobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
IOLKFBCL_01487	216816.GS08_09015	3.43e-75	226.0	COG0256@1|root,COG0256@2|Bacteria,2IKTX@201174|Actinobacteria,4D0WE@85004|Bifidobacteriales	201174|Actinobacteria	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0008150,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
IOLKFBCL_01488	216816.GS08_09010	2.82e-128	369.0	COG0098@1|root,COG0098@2|Bacteria,2GJW8@201174|Actinobacteria,4CZCD@85004|Bifidobacteriales	201174|Actinobacteria	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
IOLKFBCL_01489	216816.GS08_09005	4.64e-36	122.0	COG1841@1|root,COG1841@2|Bacteria,2GQV0@201174|Actinobacteria,4D1EZ@85004|Bifidobacteriales	201174|Actinobacteria	J	Ribosomal protein L30p/L7e	rpmD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
IOLKFBCL_01490	216816.GS08_09000	1.52e-98	286.0	COG0200@1|root,COG0200@2|Bacteria,2II6M@201174|Actinobacteria,4D0R9@85004|Bifidobacteriales	201174|Actinobacteria	J	binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
IOLKFBCL_01491	216816.GS08_08995	1.87e-316	862.0	COG0201@1|root,COG0201@2|Bacteria,2GJ26@201174|Actinobacteria,4CYWU@85004|Bifidobacteriales	201174|Actinobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
IOLKFBCL_01492	216816.GS08_08990	7.36e-128	363.0	COG0563@1|root,COG0563@2|Bacteria,2GJ7T@201174|Actinobacteria,4CZ7Z@85004|Bifidobacteriales	201174|Actinobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
IOLKFBCL_01493	1435051.BMOU_1728	6.91e-45	145.0	COG0361@1|root,COG0361@2|Bacteria,2IQ4B@201174|Actinobacteria,4D16H@85004|Bifidobacteriales	201174|Actinobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
IOLKFBCL_01494	158787.BSCA_1163	1.47e-20	81.3	COG0257@1|root,COG0257@2|Bacteria,2GWMH@201174|Actinobacteria,4D1NT@85004|Bifidobacteriales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
IOLKFBCL_01495	326426.Bbr_1617	1.16e-81	242.0	COG0099@1|root,COG0099@2|Bacteria,2IHPN@201174|Actinobacteria,4D0PQ@85004|Bifidobacteriales	201174|Actinobacteria	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
IOLKFBCL_01496	216816.GS08_08970	7.34e-86	253.0	COG0100@1|root,COG0100@2|Bacteria,2IFFC@201174|Actinobacteria,4D0PJ@85004|Bifidobacteriales	201174|Actinobacteria	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
IOLKFBCL_01497	216816.GS08_08965	4.01e-236	649.0	COG0202@1|root,COG0202@2|Bacteria,2GJJ5@201174|Actinobacteria,4CZEN@85004|Bifidobacteriales	201174|Actinobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
IOLKFBCL_01498	326426.Bbr_1614	1.83e-86	258.0	COG0203@1|root,COG0203@2|Bacteria,2IHV2@201174|Actinobacteria,4D0PZ@85004|Bifidobacteriales	201174|Actinobacteria	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
IOLKFBCL_01499	216816.GS08_08955	4.75e-214	591.0	COG0101@1|root,COG0101@2|Bacteria,2GJ6C@201174|Actinobacteria,4CZ8H@85004|Bifidobacteriales	201174|Actinobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0030312,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
IOLKFBCL_01500	216816.GS08_08945	0.0	1431.0	COG2307@1|root,COG2308@1|root,COG2307@2|Bacteria,COG2308@2|Bacteria,2GN0J@201174|Actinobacteria,4D061@85004|Bifidobacteriales	201174|Actinobacteria	S	A circularly permuted ATPgrasp	gcs2	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	Alpha-E,CP_ATPgrasp_1,CP_ATPgrasp_2,GCS2
IOLKFBCL_01501	216816.GS08_08940	2.82e-192	533.0	COG1305@1|root,COG1305@2|Bacteria,2GN5D@201174|Actinobacteria,4CZBJ@85004|Bifidobacteriales	201174|Actinobacteria	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
IOLKFBCL_01502	1437610.BREU_0640	6e-275	756.0	COG1373@1|root,COG1373@2|Bacteria,2GK4E@201174|Actinobacteria,4CZX6@85004|Bifidobacteriales	201174|Actinobacteria	S	Psort location Cytoplasmic, score	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
IOLKFBCL_01504	398513.BBNG_01833	5.07e-18	76.3	COG2801@1|root,COG2801@2|Bacteria,2H9F1@201174|Actinobacteria,4D2FY@85004|Bifidobacteriales	201174|Actinobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve_2
IOLKFBCL_01505	547043.BIFPSEUDO_03226	6.64e-205	568.0	COG1175@1|root,COG1175@2|Bacteria,2GMTW@201174|Actinobacteria,4CZW4@85004|Bifidobacteriales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
IOLKFBCL_01506	547043.BIFPSEUDO_03225	2.54e-220	609.0	COG0395@1|root,COG0395@2|Bacteria,2GJPZ@201174|Actinobacteria,4CZTQ@85004|Bifidobacteriales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
IOLKFBCL_01507	547043.BIFPSEUDO_03224	1.37e-308	844.0	COG1653@1|root,COG1653@2|Bacteria,2I5GP@201174|Actinobacteria,4D2XQ@85004|Bifidobacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1
IOLKFBCL_01508	216816.GS08_08920	3.09e-159	447.0	2B54U@1|root,31XYD@2|Bacteria,2HXKT@201174|Actinobacteria,4D0IH@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01509	216816.GS08_08915	4.19e-241	664.0	COG0195@1|root,COG0195@2|Bacteria,2GJDJ@201174|Actinobacteria,4CYTW@85004|Bifidobacteriales	201174|Actinobacteria	K	Participates in both transcription termination and antitermination	nusA	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0040007,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
IOLKFBCL_01510	216816.GS08_08910	0.0	1566.0	COG0532@1|root,COG0532@2|Bacteria,2GKPH@201174|Actinobacteria,4CZ4B@85004|Bifidobacteriales	201174|Actinobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
IOLKFBCL_01511	216816.GS08_08905	1.05e-95	280.0	COG0858@1|root,COG0858@2|Bacteria,2IKXP@201174|Actinobacteria,4CZZZ@85004|Bifidobacteriales	201174|Actinobacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
IOLKFBCL_01512	216816.GS08_08900	2.64e-267	733.0	COG0130@1|root,COG0130@2|Bacteria,2GJZK@201174|Actinobacteria,4CZED@85004|Bifidobacteriales	201174|Actinobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C,TruB_C_2,TruB_N
IOLKFBCL_01513	216816.GS08_08895	1.68e-277	758.0	COG0196@1|root,COG0196@2|Bacteria,2GKQF@201174|Actinobacteria,4CYXT@85004|Bifidobacteriales	201174|Actinobacteria	H	riboflavin kinase	ribF	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008531,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009124,GO:0009156,GO:0009161,GO:0009165,GO:0009231,GO:0009259,GO:0009260,GO:0009398,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0042364,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046444,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
IOLKFBCL_01514	216816.GS08_08890	0.0	959.0	COG1066@1|root,COG1066@2|Bacteria,2GMQ0@201174|Actinobacteria,4CZE1@85004|Bifidobacteriales	201174|Actinobacteria	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
IOLKFBCL_01515	216816.GS08_08885	5.79e-130	371.0	2EHBK@1|root,33B3F@2|Bacteria,2ICD4@201174|Actinobacteria,4CZY5@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01516	1147128.BAST_1307	5.05e-07	46.6	29UT5@1|root,30G5G@2|Bacteria,2GXCZ@201174|Actinobacteria,4D1N2@85004|Bifidobacteriales	201174|Actinobacteria	S	Mitochondrial domain of unknown function (DUF1713)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1713
IOLKFBCL_01517	216816.GS08_08875	1.44e-159	447.0	COG0120@1|root,COG0120@2|Bacteria,2GMHW@201174|Actinobacteria,4CZDH@85004|Bifidobacteriales	201174|Actinobacteria	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
IOLKFBCL_01518	216816.GS08_08870	1.38e-189	527.0	COG0328@1|root,COG0328@2|Bacteria,2GK53@201174|Actinobacteria,4CZGC@85004|Bifidobacteriales	201174|Actinobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DUF4440,RNase_H
IOLKFBCL_01520	216816.GS08_08860	0.0	980.0	COG1249@1|root,COG1249@2|Bacteria,2GJJK@201174|Actinobacteria,4CZZF@85004|Bifidobacteriales	201174|Actinobacteria	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	merA	-	1.16.1.1	ko:K00520,ko:K21739	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
IOLKFBCL_01521	216816.GS08_08855	1.06e-89	263.0	COG1959@1|root,COG1959@2|Bacteria,2IKDG@201174|Actinobacteria,4D0YZ@85004|Bifidobacteriales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
IOLKFBCL_01522	216816.GS08_08850	7.16e-118	345.0	COG2852@1|root,COG2852@2|Bacteria,2HTNX@201174|Actinobacteria,4D0CP@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01523	216816.GS08_08845	0.0	1128.0	COG0033@1|root,COG0033@2|Bacteria,2H1PI@201174|Actinobacteria,4CZ7X@85004|Bifidobacteriales	201174|Actinobacteria	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II	pgm	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
IOLKFBCL_01524	326426.Bbr_1594	0.0	1248.0	COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,2GK6B@201174|Actinobacteria,4CZR7@85004|Bifidobacteriales	201174|Actinobacteria	G	pts system, glucose-specific IIABC component	ptsG	-	-	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	M00271	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6	-	-	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
IOLKFBCL_01525	326426.Bbr_1593	6.92e-204	565.0	COG3711@1|root,COG3711@2|Bacteria,2I8K8@201174|Actinobacteria,4D08T@85004|Bifidobacteriales	201174|Actinobacteria	K	CAT RNA binding domain	arbG	-	-	ko:K03488	-	-	-	-	ko00000,ko03000	-	-	-	CAT_RBD,PRD,PTS-HPr
IOLKFBCL_01526	216816.GS08_08825	4.92e-266	730.0	COG1597@1|root,COG1597@2|Bacteria,2GJ3K@201174|Actinobacteria,4CYTC@85004|Bifidobacteriales	201174|Actinobacteria	I	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
IOLKFBCL_01527	216816.GS08_08820	9.91e-302	823.0	COG0172@1|root,COG0172@2|Bacteria,2GIWP@201174|Actinobacteria,4CZ40@85004|Bifidobacteriales	201174|Actinobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
IOLKFBCL_01529	216816.GS08_08740	0.0	1525.0	COG5426@1|root,COG5426@2|Bacteria,2GN2A@201174|Actinobacteria,4CYZB@85004|Bifidobacteriales	201174|Actinobacteria	S	Lacto-N-biose phosphorylase C-terminal domain	gnpA	-	2.4.1.211	ko:K15533	-	-	-	-	ko00000,ko01000	-	-	-	LBP_C,LBP_M,Lact_bio_phlase
IOLKFBCL_01530	216816.GS08_08735	2.22e-238	657.0	COG2334@1|root,COG2334@2|Bacteria,2I8JD@201174|Actinobacteria,4D06K@85004|Bifidobacteriales	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	2.7.1.162	ko:K13059	-	-	R08962	RC00002,RC00078	ko00000,ko01000	-	-	-	APH
IOLKFBCL_01531	216816.GS08_08730	0.0	1040.0	COG4468@1|root,COG4468@2|Bacteria,2HNCF@201174|Actinobacteria,4CZT3@85004|Bifidobacteriales	201174|Actinobacteria	G	UDP-glucose--hexose-1-phosphate uridylyltransferase	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
IOLKFBCL_01532	1437610.BREU_1776	9.84e-237	652.0	COG1087@1|root,COG1087@2|Bacteria,2GMCW@201174|Actinobacteria,4CZDB@85004|Bifidobacteriales	201174|Actinobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
IOLKFBCL_01533	326426.Bbr_1584	1.17e-143	407.0	COG2197@1|root,COG2197@2|Bacteria,2GIVA@201174|Actinobacteria,4CZW8@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	tcsR3	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
IOLKFBCL_01534	216816.GS08_08715	1.2e-287	787.0	COG1983@1|root,COG4585@1|root,COG1983@2|Bacteria,COG4585@2|Bacteria,2GJ4J@201174|Actinobacteria,4CZ2U@85004|Bifidobacteriales	201174|Actinobacteria	KT	PspC domain	tcsS3	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_2,PspC
IOLKFBCL_01535	216816.GS08_08710	4.44e-231	650.0	COG1983@1|root,COG1983@2|Bacteria,2GIVS@201174|Actinobacteria,4CZZT@85004|Bifidobacteriales	201174|Actinobacteria	KT	PspC domain	pspC	-	-	-	-	-	-	-	-	-	-	-	DUF2154,PspC
IOLKFBCL_01536	216816.GS08_08705	3.53e-101	300.0	2BIES@1|root,32CM6@2|Bacteria,2GSGC@201174|Actinobacteria,4D1KF@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01537	216816.GS08_08700	0.0	970.0	COG1073@1|root,COG1073@2|Bacteria,2H036@201174|Actinobacteria,4CYRR@85004|Bifidobacteriales	201174|Actinobacteria	S	alpha beta	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	BAAT_C,Hydrolase_4,Peptidase_S9
IOLKFBCL_01538	216816.GS08_08695	1.34e-144	408.0	2DM2Z@1|root,31HGC@2|Bacteria,2GKMX@201174|Actinobacteria,4CZJ9@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF4125)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4125
IOLKFBCL_01539	1437610.BREU_1769	0.0	1002.0	COG0457@1|root,COG0457@2|Bacteria,2I7P1@201174|Actinobacteria,4CZTS@85004|Bifidobacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4037)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4037,TPR_12
IOLKFBCL_01540	1437610.BREU_1768	0.0	2047.0	COG0671@1|root,COG0737@1|root,COG0671@2|Bacteria,COG0737@2|Bacteria,2I4ZG@201174|Actinobacteria,4CZ80@85004|Bifidobacteriales	201174|Actinobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid_C,Metallophos,PAP2
IOLKFBCL_01541	326426.Bbr_1577	2.71e-262	721.0	COG0477@1|root,COG2814@2|Bacteria,2GK8C@201174|Actinobacteria,4CZ46@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	ko:K08156,ko:K19577	-	-	-	-	ko00000,ko02000	2.A.1.2.14,2.A.1.2.65	-	-	MFS_1
IOLKFBCL_01543	216816.GS08_08675	0.0	1098.0	COG1190@1|root,COG1190@2|Bacteria,2GKE0@201174|Actinobacteria,4CZHM@85004|Bifidobacteriales	201174|Actinobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	GO:0008150,GO:0040007	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
IOLKFBCL_01544	216816.GS08_08670	6.97e-216	597.0	COG1575@1|root,COG1575@2|Bacteria,2GJBS@201174|Actinobacteria,4CZHQ@85004|Bifidobacteriales	201174|Actinobacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	GO:0003674,GO:0003824,GO:0004659,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
IOLKFBCL_01545	216816.GS08_08665	3.69e-178	496.0	COG0588@1|root,COG0588@2|Bacteria,2GK8F@201174|Actinobacteria,4CZMF@85004|Bifidobacteriales	201174|Actinobacteria	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmA	GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0031323,GO:0031329,GO:0032787,GO:0032991,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0060255,GO:0062012,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
IOLKFBCL_01546	216816.GS08_08660	2.46e-147	416.0	COG0704@1|root,COG0704@2|Bacteria,2GKAD@201174|Actinobacteria,4CZ9B@85004|Bifidobacteriales	201174|Actinobacteria	P	Plays a role in the regulation of phosphate uptake	phoU	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0016020,GO:0019220,GO:0019222,GO:0022611,GO:0031323,GO:0031324,GO:0032502,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042221,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044444,GO:0044464,GO:0045936,GO:0046677,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:0071944,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
IOLKFBCL_01547	216816.GS08_08655	6.48e-254	700.0	COG5002@1|root,COG5002@2|Bacteria,2GJY7@201174|Actinobacteria,4CZIM@85004|Bifidobacteriales	201174|Actinobacteria	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	senX3	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009405,GO:0009987,GO:0016020,GO:0016310,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0051704,GO:0071704,GO:0071944,GO:1901564	2.7.13.3	ko:K07768	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
IOLKFBCL_01548	216816.GS08_08650	1.97e-50	160.0	2EG1H@1|root,339TH@2|Bacteria,2IQTR@201174|Actinobacteria,4D16E@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2530
IOLKFBCL_01549	216816.GS08_08645	6.07e-274	749.0	COG1932@1|root,COG1932@2|Bacteria,2GKYK@201174|Actinobacteria,4CZ94@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005886,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0040007,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
IOLKFBCL_01550	216816.GS08_08640	1.85e-214	593.0	COG3942@1|root,COG3942@2|Bacteria,2GP2A@201174|Actinobacteria,4CYXV@85004|Bifidobacteriales	201174|Actinobacteria	S	CHAP domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAP
IOLKFBCL_01551	216816.GS08_08635	3.42e-118	343.0	COG0791@1|root,COG0791@2|Bacteria,2IBQZ@201174|Actinobacteria,4CYXI@85004|Bifidobacteriales	201174|Actinobacteria	M	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
IOLKFBCL_01552	216816.GS08_08630	1.81e-137	393.0	COG0791@1|root,COG0791@2|Bacteria,2GJX7@201174|Actinobacteria,4D01Q@85004|Bifidobacteriales	201174|Actinobacteria	M	NlpC/P60 family	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60,PG_binding_1,SLT
IOLKFBCL_01553	216816.GS08_08625	3.06e-238	656.0	COG0589@1|root,COG0589@2|Bacteria,2GMFE@201174|Actinobacteria,4CZ6V@85004|Bifidobacteriales	201174|Actinobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
IOLKFBCL_01554	216816.GS08_08620	9.14e-96	278.0	COG1765@1|root,COG1765@2|Bacteria,2IIK7@201174|Actinobacteria,4D0PB@85004|Bifidobacteriales	201174|Actinobacteria	O	OsmC-like protein	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	OsmC
IOLKFBCL_01555	216816.GS08_08615	8.29e-222	610.0	COG0207@1|root,COG0207@2|Bacteria,2GKY0@201174|Actinobacteria,4CZQ3@85004|Bifidobacteriales	201174|Actinobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009125,GO:0009129,GO:0009130,GO:0009131,GO:0009157,GO:0009159,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009178,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0032259,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042083,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046073,GO:0046078,GO:0046079,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
IOLKFBCL_01557	216816.GS08_08610	6.93e-161	450.0	COG0262@1|root,COG0262@2|Bacteria,2IM1S@201174|Actinobacteria,4CZM1@85004|Bifidobacteriales	201174|Actinobacteria	H	dihydrofolate reductase	folA	GO:0000166,GO:0003674,GO:0003824,GO:0004146,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0070401,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2763c	DHFR_1
IOLKFBCL_01558	216816.GS08_08605	2.08e-127	361.0	COG0394@1|root,COG0394@2|Bacteria,2IM0Q@201174|Actinobacteria,4CZWM@85004|Bifidobacteriales	201174|Actinobacteria	T	low molecular weight	ptpA	GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009405,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0035335,GO:0035821,GO:0036211,GO:0042578,GO:0043170,GO:0043207,GO:0043412,GO:0044003,GO:0044046,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052046,GO:0052047,GO:0052048,GO:0052083,GO:0052155,GO:0052173,GO:0052200,GO:0052212,GO:0052255,GO:0052278,GO:0052294,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0071704,GO:0071944,GO:0075136,GO:0140096,GO:1901564	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
IOLKFBCL_01559	216816.GS08_02130	1.98e-142	402.0	COG1136@1|root,COG1136@2|Bacteria,2I7UV@201174|Actinobacteria,4CZ1C@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter, ATP-binding protein	vex	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IOLKFBCL_01560	326426.Bbr_1559	6.2e-267	734.0	COG0577@1|root,COG0577@2|Bacteria,2IA7B@201174|Actinobacteria,4CZJM@85004|Bifidobacteriales	201174|Actinobacteria	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
IOLKFBCL_01561	702459.BBPR_1469	7.23e-288	791.0	COG0577@1|root,COG0577@2|Bacteria,2I99G@201174|Actinobacteria,4D0H6@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter permease	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
IOLKFBCL_01562	216816.GS08_07805	2.77e-290	793.0	COG0192@1|root,COG0192@2|Bacteria,2GJ4U@201174|Actinobacteria,4CZ5D@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0016740,GO:0016765,GO:0019899,GO:0030312,GO:0035375,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
IOLKFBCL_01563	216816.GS08_07800	1.34e-61	189.0	COG1758@1|root,COG1758@2|Bacteria,2IQHU@201174|Actinobacteria,4D12C@85004|Bifidobacteriales	201174|Actinobacteria	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
IOLKFBCL_01564	216816.GS08_07795	0.0	1181.0	COG0129@1|root,COG0129@2|Bacteria,2GJIJ@201174|Actinobacteria,4CZ1T@85004|Bifidobacteriales	201174|Actinobacteria	H	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
IOLKFBCL_01565	216816.GS08_07790	1.14e-229	633.0	COG0223@1|root,COG0223@2|Bacteria,2GKH5@201174|Actinobacteria,4CZ8C@85004|Bifidobacteriales	201174|Actinobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0040007,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
IOLKFBCL_01566	216816.GS08_07785	1.69e-168	470.0	COG1011@1|root,COG1011@2|Bacteria,2I8XE@201174|Actinobacteria,4CZGV@85004|Bifidobacteriales	201174|Actinobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	3.8.1.2	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
IOLKFBCL_01567	216816.GS08_07780	0.0	1502.0	COG1198@1|root,COG1198@2|Bacteria,2GKES@201174|Actinobacteria,4D04J@85004|Bifidobacteriales	201174|Actinobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
IOLKFBCL_01568	216816.GS08_07775	7.09e-164	459.0	COG0560@1|root,COG0560@2|Bacteria,2GJDH@201174|Actinobacteria,4CYWC@85004|Bifidobacteriales	201174|Actinobacteria	E	haloacid dehalogenase-like hydrolase	serB	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	HAD
IOLKFBCL_01569	216816.GS08_07770	9.02e-163	456.0	COG0586@1|root,COG0586@2|Bacteria,2GN43@201174|Actinobacteria,4CZZA@85004|Bifidobacteriales	201174|Actinobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
IOLKFBCL_01570	216816.GS08_07765	0.0	987.0	COG1222@1|root,COG1222@2|Bacteria,2GMR1@201174|Actinobacteria,4CZ86@85004|Bifidobacteriales	201174|Actinobacteria	O	AAA ATPase forming ring-shaped complexes	arc	GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369	-	ko:K13527	ko03050,map03050	M00342	-	-	ko00000,ko00001,ko00002,ko03051	-	-	-	AAA,Prot_ATP_ID_OB
IOLKFBCL_01571	216816.GS08_07760	0.0	1085.0	COG4122@1|root,COG4122@2|Bacteria,2GJGI@201174|Actinobacteria,4CZAN@85004|Bifidobacteriales	201174|Actinobacteria	S	Pup-ligase protein	dop	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	3.5.1.119	ko:K20814	-	-	-	-	ko00000,ko01000,ko03051	-	-	-	Pup_ligase
IOLKFBCL_01572	216816.GS08_07755	1.94e-215	594.0	COG0483@1|root,COG0483@2|Bacteria,2HGP2@201174|Actinobacteria,4CYWZ@85004|Bifidobacteriales	201174|Actinobacteria	G	Inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
IOLKFBCL_01573	216816.GS08_07750	5.61e-24	92.0	2B5FT@1|root,31YAF@2|Bacteria,2GV5R@201174|Actinobacteria	201174|Actinobacteria	S	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation	pup	-	-	ko:K13570	-	-	-	-	ko00000,ko04121	-	-	-	Pup
IOLKFBCL_01574	216816.GS08_07745	0.0	930.0	COG0638@1|root,COG0638@2|Bacteria,2GMC6@201174|Actinobacteria,4CZ12@85004|Bifidobacteriales	201174|Actinobacteria	O	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine	pafA	GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170	6.3.1.19	ko:K13571	-	M00342	R11207	RC00090,RC00096	ko00000,ko00002,ko01000,ko03051	-	-	-	Pup_ligase
IOLKFBCL_01575	702459.BBPR_0164	0.0	1391.0	COG1874@1|root,COG1874@2|Bacteria,2GMDT@201174|Actinobacteria,4CZ38@85004|Bifidobacteriales	201174|Actinobacteria	G	Psort location Cytoplasmic, score 8.87	bga1	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
IOLKFBCL_01576	398513.BBNG_00086	0.0	1540.0	COG1409@1|root,COG1409@2|Bacteria,2GNU9@201174|Actinobacteria,4CZXA@85004|Bifidobacteriales	201174|Actinobacteria	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,Metallophos
IOLKFBCL_01578	762211.BSTEL_0666	9.03e-200	563.0	COG1672@1|root,COG1672@2|Bacteria,2GWBV@201174|Actinobacteria,4D1CX@85004|Bifidobacteriales	201174|Actinobacteria	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
IOLKFBCL_01579	1437609.BCAL_0001	1.04e-24	98.6	COG3464@1|root,COG3464@2|Bacteria,2I00A@201174|Actinobacteria,4D2GS@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3
IOLKFBCL_01580	1437608.BBIA_1622	3.74e-300	825.0	COG2865@1|root,COG2865@2|Bacteria,2IC6C@201174|Actinobacteria,4D0AE@85004|Bifidobacteriales	201174|Actinobacteria	K	Putative DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4
IOLKFBCL_01581	1437610.BREU_0807	8.3e-78	234.0	28PY9@1|root,2ZCI0@2|Bacteria,2INBV@201174|Actinobacteria,4D13Q@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01583	326426.Bbr_0430	2.15e-291	809.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2GK0M@201174|Actinobacteria,4CZ4J@85004|Bifidobacteriales	201174|Actinobacteria	M	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase	rfbP	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
IOLKFBCL_01584	326426.Bbr_0431	2.45e-139	394.0	COG0394@1|root,COG0394@2|Bacteria,2GMPR@201174|Actinobacteria,4D0GD@85004|Bifidobacteriales	201174|Actinobacteria	T	Low molecular weight phosphatase family	etp	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
IOLKFBCL_01585	1437609.BCAL_0960	5.16e-140	416.0	2C04M@1|root,32Y5W@2|Bacteria,2IBPG@201174|Actinobacteria,4D07E@85004|Bifidobacteriales	201174|Actinobacteria	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01586	401473.BDP_1864	4.79e-210	588.0	COG0438@1|root,COG0438@2|Bacteria,2IBM0@201174|Actinobacteria,4D1CU@85004|Bifidobacteriales	201174|Actinobacteria	M	Domain of unknown function (DUF1972)	-	-	-	ko:K12996	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	DUF1972,Glyco_trans_1_2,Glyco_trans_1_4,Glyco_trans_4_4,Glycos_transf_1
IOLKFBCL_01587	1410638.JHXJ01000010_gene86	1.36e-214	600.0	COG0438@1|root,COG0438@2|Bacteria,1V0JW@1239|Firmicutes,24CKB@186801|Clostridia,3WPMK@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
IOLKFBCL_01588	1423758.BN55_01225	1.14e-63	204.0	COG0110@1|root,COG0110@2|Bacteria,1VFFY@1239|Firmicutes,4HVGV@91061|Bacilli,3F73M@33958|Lactobacillaceae	91061|Bacilli	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
IOLKFBCL_01589	1414720.CBYM010000011_gene2614	8.53e-36	139.0	COG0463@1|root,COG0463@2|Bacteria,1VVRP@1239|Firmicutes,24AI7@186801|Clostridia	186801|Clostridia	M	Glycosyltransferase, group 2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
IOLKFBCL_01590	768710.DesyoDRAFT_4919	5.33e-10	69.3	COG3307@1|root,COG3307@2|Bacteria,1VNEW@1239|Firmicutes,24UU5@186801|Clostridia	186801|Clostridia	M	O-antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
IOLKFBCL_01591	518635.BIFANG_03170	3.78e-172	498.0	COG2244@1|root,COG2244@2|Bacteria,2IA1K@201174|Actinobacteria,4D0KU@85004|Bifidobacteriales	201174|Actinobacteria	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
IOLKFBCL_01592	518635.BIFANG_03173	6.27e-147	428.0	COG1143@1|root,COG1143@2|Bacteria,2I42G@201174|Actinobacteria,4D2WE@85004|Bifidobacteriales	201174|Actinobacteria	C	Polysaccharide pyruvyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
IOLKFBCL_01593	1175629.AJTG01000006_gene498	6.22e-56	189.0	2CEUT@1|root,2Z86D@2|Bacteria,1V5U9@1239|Firmicutes,4HJKI@91061|Bacilli	91061|Bacilli	S	Core-2/I-Branching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Branch
IOLKFBCL_01595	1680.BADO_1356	5.01e-255	698.0	COG1088@1|root,COG1088@2|Bacteria,2GNDU@201174|Actinobacteria,4CZZY@85004|Bifidobacteriales	201174|Actinobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3464	GDP_Man_Dehyd
IOLKFBCL_01596	1035195.HMPREF9997_00461	2.51e-25	107.0	arCOG08992@1|root,30Q1U@2|Bacteria,2GRWJ@201174|Actinobacteria,22MI1@1653|Corynebacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Abi_2
IOLKFBCL_01597	78346.BRUM_1818	0.0	912.0	COG1091@1|root,COG1898@1|root,COG1091@2|Bacteria,COG1898@2|Bacteria,2GNY8@201174|Actinobacteria,4CZ18@85004|Bifidobacteriales	201174|Actinobacteria	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133,5.1.3.13	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777,R06514	RC00182,RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind,dTDP_sugar_isom
IOLKFBCL_01598	78344.BIGA_0353	5.16e-217	598.0	COG1209@1|root,COG1209@2|Bacteria,2GP20@201174|Actinobacteria,4CZ5F@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005996,GO:0006006,GO:0006139,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008879,GO:0009058,GO:0009059,GO:0009117,GO:0009141,GO:0009147,GO:0009200,GO:0009211,GO:0009219,GO:0009225,GO:0009226,GO:0009262,GO:0009394,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019299,GO:0019300,GO:0019305,GO:0019318,GO:0019319,GO:0019438,GO:0019637,GO:0019692,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0045226,GO:0046075,GO:0046364,GO:0046379,GO:0046383,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0334	NTP_transferase
IOLKFBCL_01600	31954.BPSP_0710	4.71e-27	110.0	COG3274@1|root,COG3274@2|Bacteria,2GITX@201174|Actinobacteria,4D0JX@85004|Bifidobacteriales	201174|Actinobacteria	S	enterobacterial common antigen metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
IOLKFBCL_01601	216816.GS08_09885	4.67e-315	863.0	COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,2GKW1@201174|Actinobacteria,4CYXY@85004|Bifidobacteriales	201174|Actinobacteria	L	HTH-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve,rve_2
IOLKFBCL_01602	1437608.BBIA_1061	7.38e-44	145.0	COG2963@1|root,COG2963@2|Bacteria,2IQ8F@201174|Actinobacteria,4D1BJ@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
IOLKFBCL_01603	1437608.BBIA_1062	6.24e-184	516.0	COG2801@1|root,COG2801@2|Bacteria,2GKDY@201174|Actinobacteria,4CZUB@85004|Bifidobacteriales	201174|Actinobacteria	L	Integrase core domain	tnp3521a2	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve,rve_3
IOLKFBCL_01604	699248.SRA_06071	1.2e-60	205.0	2C171@1|root,2Z7ZR@2|Bacteria,1VCWV@1239|Firmicutes,4HNFG@91061|Bacilli	91061|Bacilli	S	SIR2-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2
IOLKFBCL_01605	78345.BMERY_1183	0.0	1192.0	COG0433@1|root,COG0433@2|Bacteria,2INIE@201174|Actinobacteria,4D1JH@85004|Bifidobacteriales	201174|Actinobacteria	S	AAA-like domain	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF87
IOLKFBCL_01606	78346.BRUM_0813	2.27e-64	201.0	COG2963@1|root,COG2963@2|Bacteria,2IF4K@201174|Actinobacteria,4D0JP@85004|Bifidobacteriales	201174|Actinobacteria	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_28
IOLKFBCL_01607	944560.HMPREF9058_1962	2.07e-33	116.0	2E7PK@1|root,33256@2|Bacteria,2ISIC@201174|Actinobacteria,4D6CQ@85005|Actinomycetales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01609	78344.BIGA_0353	1.18e-24	99.0	COG1209@1|root,COG1209@2|Bacteria,2GP20@201174|Actinobacteria,4CZ5F@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005996,GO:0006006,GO:0006139,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008879,GO:0009058,GO:0009059,GO:0009117,GO:0009141,GO:0009147,GO:0009200,GO:0009211,GO:0009219,GO:0009225,GO:0009226,GO:0009262,GO:0009394,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019299,GO:0019300,GO:0019305,GO:0019318,GO:0019319,GO:0019438,GO:0019637,GO:0019692,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0045226,GO:0046075,GO:0046364,GO:0046379,GO:0046383,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0334	NTP_transferase
IOLKFBCL_01611	1680.BADO_1369	8.31e-115	333.0	2B5AK@1|root,31Y4R@2|Bacteria,2IPRY@201174|Actinobacteria,4D15E@85004|Bifidobacteriales	201174|Actinobacteria	S	RloB-like protein	-	-	-	-	-	-	-	-	-	-	-	-	RloB
IOLKFBCL_01612	1680.BADO_1370	5.66e-235	655.0	COG1106@1|root,COG1106@2|Bacteria,2GMVX@201174|Actinobacteria,4CZWP@85004|Bifidobacteriales	201174|Actinobacteria	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K06926	-	-	-	-	ko00000	-	-	-	AAA_21
IOLKFBCL_01613	547043.BIFPSEUDO_03283	3.64e-30	109.0	COG3274@1|root,COG3274@2|Bacteria,2GITX@201174|Actinobacteria,4D0JX@85004|Bifidobacteriales	201174|Actinobacteria	S	enterobacterial common antigen metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
IOLKFBCL_01614	1680.BADO_1363	8.49e-18	82.8	COG3274@1|root,COG3274@2|Bacteria,2GITX@201174|Actinobacteria,4D0JX@85004|Bifidobacteriales	201174|Actinobacteria	S	enterobacterial common antigen metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
IOLKFBCL_01615	326426.Bbr_0472	0.0	904.0	2C04M@1|root,32Y5W@2|Bacteria,2IBPG@201174|Actinobacteria,4D07E@85004|Bifidobacteriales	201174|Actinobacteria	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01616	326426.Bbr_0474	2.32e-314	860.0	COG0489@1|root,COG3944@1|root,COG0489@2|Bacteria,COG3944@2|Bacteria,2GJ1Y@201174|Actinobacteria,4CZKW@85004|Bifidobacteriales	201174|Actinobacteria	DM	Psort location CytoplasmicMembrane, score	wcoI	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,GNVR,ParA,Wzz
IOLKFBCL_01617	216816.GS08_02285	2.28e-258	716.0	2DDMI@1|root,2ZIJN@2|Bacteria,2ICIR@201174|Actinobacteria,4D00F@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	FIVAR
IOLKFBCL_01618	216816.GS08_02295	1.35e-216	600.0	COG3583@1|root,COG3583@2|Bacteria,2I2GH@201174|Actinobacteria,4CYVC@85004|Bifidobacteriales	201174|Actinobacteria	S	G5	-	-	-	ko:K21688	-	-	-	-	ko00000	-	-	-	DUF348,G5,SLT
IOLKFBCL_01619	216816.GS08_02300	5.55e-79	235.0	COG0526@1|root,COG0526@2|Bacteria,2IKP1@201174|Actinobacteria,4D11J@85004|Bifidobacteriales	201174|Actinobacteria	O	Belongs to the thioredoxin family	trxA	-	1.8.1.9	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000,ko03110	-	-	-	Thioredoxin
IOLKFBCL_01620	216816.GS08_02305	1.46e-162	454.0	COG1051@1|root,COG1051@2|Bacteria,2GJGZ@201174|Actinobacteria,4CYT1@85004|Bifidobacteriales	201174|Actinobacteria	F	Domain of unknown function (DUF4916)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4916
IOLKFBCL_01621	216816.GS08_02310	8.16e-206	569.0	COG2267@1|root,COG2267@2|Bacteria,2I2GI@201174|Actinobacteria,4CYXW@85004|Bifidobacteriales	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
IOLKFBCL_01622	216816.GS08_02315	3.25e-292	800.0	COG2816@1|root,COG2816@2|Bacteria,2GJZY@201174|Actinobacteria,4CZE5@85004|Bifidobacteriales	201174|Actinobacteria	L	NADH pyrophosphatase zinc ribbon domain	nudC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.1.22	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	-	R00103,R03004,R11104	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,NUDIX-like,zf-NADH-PPase
IOLKFBCL_01623	216816.GS08_02320	1.66e-93	273.0	COG0509@1|root,COG0509@2|Bacteria,2IKN2@201174|Actinobacteria,4D0W7@85004|Bifidobacteriales	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
IOLKFBCL_01624	216816.GS08_09320	5.43e-152	429.0	COG3464@1|root,COG3464@2|Bacteria,2IP45@201174|Actinobacteria,4D04T@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
IOLKFBCL_01625	641146.HMPREF9020_01335	0.0	1414.0	COG0577@1|root,COG0577@2|Bacteria,2I2FK@201174|Actinobacteria,4CZJR@85004|Bifidobacteriales	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
IOLKFBCL_01626	641146.HMPREF9020_01336	1.33e-160	450.0	COG1136@1|root,COG1136@2|Bacteria,2GJQV@201174|Actinobacteria,4CYT2@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IOLKFBCL_01627	641146.HMPREF9020_01337	1.4e-140	397.0	COG1309@1|root,COG1309@2|Bacteria,2HZES@201174|Actinobacteria,4D04U@85004|Bifidobacteriales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
IOLKFBCL_01628	1437608.BBIA_0139	4.16e-44	155.0	COG1373@1|root,COG1373@2|Bacteria,2HCYQ@201174|Actinobacteria,4D2TP@85004|Bifidobacteriales	201174|Actinobacteria	S	AAA domain	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
IOLKFBCL_01629	216816.GS08_03195	7.11e-172	480.0	COG1304@1|root,COG1304@2|Bacteria,2HHRH@201174|Actinobacteria,4CZI2@85004|Bifidobacteriales	201174|Actinobacteria	C	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01630	216816.GS08_03190	3e-124	357.0	COG1846@1|root,COG1846@2|Bacteria,2GSTZ@201174|Actinobacteria,4D1IE@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
IOLKFBCL_01631	357809.Cphy_0738	5.1e-07	48.9	COG0789@1|root,COG0789@2|Bacteria,1VAAP@1239|Firmicutes,24JJN@186801|Clostridia,220XT@1506553|Lachnoclostridium	186801|Clostridia	K	MerR, DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
IOLKFBCL_01632	326426.Bbr_0616	0.0	891.0	COG1373@1|root,COG1373@2|Bacteria,2HJ52@201174|Actinobacteria,4D2TQ@85004|Bifidobacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
IOLKFBCL_01633	326426.Bbr_0615	2.35e-243	669.0	COG1063@1|root,COG1063@2|Bacteria,2GISW@201174|Actinobacteria,4CZJY@85004|Bifidobacteriales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	adh	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
IOLKFBCL_01634	326426.Bbr_0614	2.34e-21	87.0	COG0789@1|root,COG0789@2|Bacteria,2HZK3@201174|Actinobacteria,4D0RM@85004|Bifidobacteriales	201174|Actinobacteria	K	MerR family regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR_1
IOLKFBCL_01635	326426.Bbr_0614	8.54e-24	93.2	COG0789@1|root,COG0789@2|Bacteria,2HZK3@201174|Actinobacteria,4D0RM@85004|Bifidobacteriales	201174|Actinobacteria	K	MerR family regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR_1
IOLKFBCL_01636	216816.GS08_03135	1.43e-112	324.0	COG0239@1|root,COG0239@2|Bacteria,2IJGQ@201174|Actinobacteria,4D11I@85004|Bifidobacteriales	201174|Actinobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	-	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
IOLKFBCL_01637	326426.Bbr_0612	5.59e-78	232.0	COG0239@1|root,COG0239@2|Bacteria,2IC26@201174|Actinobacteria,4D14T@85004|Bifidobacteriales	201174|Actinobacteria	U	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
IOLKFBCL_01638	158787.BSCA_2006	8.44e-39	135.0	COG2246@1|root,COG2246@2|Bacteria,2II4Y@201174|Actinobacteria,4D0YG@85004|Bifidobacteriales	201174|Actinobacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
IOLKFBCL_01639	326426.Bbr_0610	1.69e-235	650.0	COG2855@1|root,COG2855@2|Bacteria,2GS6E@201174|Actinobacteria,4CZWB@85004|Bifidobacteriales	201174|Actinobacteria	S	Conserved hypothetical protein 698	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
IOLKFBCL_01640	326426.Bbr_0609	1.49e-185	516.0	COG0583@1|root,COG0583@2|Bacteria,2HZCS@201174|Actinobacteria,4CZT1@85004|Bifidobacteriales	201174|Actinobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
IOLKFBCL_01641	326426.Bbr_0608	1.17e-127	365.0	28XY7@1|root,2ZJU4@2|Bacteria,2GN31@201174|Actinobacteria,4CZQG@85004|Bifidobacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4391)	tmp1	-	-	-	-	-	-	-	-	-	-	-	DUF4391
IOLKFBCL_01642	216816.GS08_03105	3.37e-292	797.0	COG0050@1|root,COG0050@2|Bacteria,2GK4T@201174|Actinobacteria,4CYY7@85004|Bifidobacteriales	201174|Actinobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0019899,GO:0030312,GO:0035375,GO:0036293,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
IOLKFBCL_01643	216816.GS08_03100	0.0	1399.0	COG0480@1|root,COG0480@2|Bacteria,2GKB3@201174|Actinobacteria,4CYTB@85004|Bifidobacteriales	201174|Actinobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
IOLKFBCL_01644	1437610.BREU_2069	1.9e-104	302.0	COG0049@1|root,COG0049@2|Bacteria,2GMVW@201174|Actinobacteria,4CZQJ@85004|Bifidobacteriales	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
IOLKFBCL_01645	1437608.BBIA_0395	5.77e-81	240.0	COG0048@1|root,COG0048@2|Bacteria,2IHUF@201174|Actinobacteria,4D0PK@85004|Bifidobacteriales	201174|Actinobacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
IOLKFBCL_01647	216816.GS08_03085	2.07e-240	662.0	COG0385@1|root,COG0385@2|Bacteria,2GMAM@201174|Actinobacteria,4CZ1K@85004|Bifidobacteriales	201174|Actinobacteria	S	SBF-like CPA transporter family (DUF4137)	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
IOLKFBCL_01649	216816.GS08_03075	2.18e-245	674.0	COG2008@1|root,COG2008@2|Bacteria,2GJ0V@201174|Actinobacteria,4CZ7G@85004|Bifidobacteriales	201174|Actinobacteria	E	Beta-eliminating lyase	ltaE	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
IOLKFBCL_01650	216816.GS08_03070	2.78e-273	748.0	COG0438@1|root,COG0438@2|Bacteria,2HEH6@201174|Actinobacteria,4CZSN@85004|Bifidobacteriales	201174|Actinobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
IOLKFBCL_01651	326426.Bbr_0600	1.26e-240	667.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,4CZCF@85004|Bifidobacteriales	201174|Actinobacteria	E	Aminotransferase class I and II	-	-	2.6.1.1,2.6.1.2,2.6.1.66,2.6.1.83	ko:K00812,ko:K08969,ko:K10206,ko:K14260,ko:K14261	ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	M00034,M00527	R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052,R07396,R07613	RC00006,RC00008,RC00036,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
IOLKFBCL_01652	216816.GS08_03065	3.37e-296	812.0	COG0027@1|root,COG0027@2|Bacteria,2GMCS@201174|Actinobacteria,4CZXH@85004|Bifidobacteriales	201174|Actinobacteria	F	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate	purT	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008776,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0044237,GO:0044424,GO:0044444,GO:0044464	2.1.2.2	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0389	ATP-grasp,Epimerase
IOLKFBCL_01653	158787.BSCA_2049	4.25e-82	243.0	COG0346@1|root,COG0346@2|Bacteria,2II51@201174|Actinobacteria,4D0V7@85004|Bifidobacteriales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	gloA	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
IOLKFBCL_01654	326426.Bbr_0598	9.74e-176	490.0	COG0152@1|root,COG0152@2|Bacteria,2GK3H@201174|Actinobacteria,4CZGQ@85004|Bifidobacteriales	201174|Actinobacteria	F	Belongs to the SAICAR synthetase family	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
IOLKFBCL_01655	216816.GS08_03050	0.0	2397.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,2GKG6@201174|Actinobacteria,4CZ7C@85004|Bifidobacteriales	201174|Actinobacteria	F	CobB/CobQ-like glutamine amidotransferase domain	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
IOLKFBCL_01656	216816.GS08_03045	2.5e-235	654.0	COG0657@1|root,COG0657@2|Bacteria,2GKX2@201174|Actinobacteria,4CYYK@85004|Bifidobacteriales	201174|Actinobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
IOLKFBCL_01657	216816.GS08_03040	0.0	888.0	COG1020@1|root,COG1020@2|Bacteria,2H4CN@201174|Actinobacteria,4D0AP@85004|Bifidobacteriales	201174|Actinobacteria	Q	D-alanine [D-alanyl carrier protein] ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01658	216816.GS08_03035	7.04e-140	397.0	COG1020@1|root,COG1020@2|Bacteria,2GIS8@201174|Actinobacteria,4D0BP@85004|Bifidobacteriales	201174|Actinobacteria	Q	D-alanine [D-alanyl carrier protein] ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01659	326426.Bbr_0588	9.34e-130	368.0	COG3663@1|root,COG3663@2|Bacteria,2IGMS@201174|Actinobacteria,4D0QQ@85004|Bifidobacteriales	201174|Actinobacteria	L	Uracil DNA glycosylase superfamily	nnrE	-	-	-	-	-	-	-	-	-	-	-	UDG,YjeF_N
IOLKFBCL_01660	1437610.BREU_0673	1.51e-215	602.0	COG3550@1|root,COG3550@2|Bacteria,2IA5Z@201174|Actinobacteria,4D09R@85004|Bifidobacteriales	201174|Actinobacteria	S	HipA N-terminal domain	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
IOLKFBCL_01661	158787.BSCA_2216	5.22e-13	67.4	COG0667@1|root,COG0667@2|Bacteria,2GMT5@201174|Actinobacteria,4CZ8K@85004|Bifidobacteriales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
IOLKFBCL_01662	1437610.BREU_0675	4.32e-58	188.0	COG0667@1|root,COG0667@2|Bacteria,2GMT5@201174|Actinobacteria,4CZ8K@85004|Bifidobacteriales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
IOLKFBCL_01663	216816.GS08_02985	9.47e-43	139.0	2DTWH@1|root,33MZC@2|Bacteria,2GUGG@201174|Actinobacteria,4D1FM@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01664	216816.GS08_02980	0.0	941.0	COG0389@1|root,COG0389@2|Bacteria,2GQX7@201174|Actinobacteria,4CZ0D@85004|Bifidobacteriales	201174|Actinobacteria	L	DNA-damage repair protein (DNA polymerase IV) K00961	-	-	-	ko:K03502	-	-	-	-	ko00000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
IOLKFBCL_01665	1437610.BREU_0654	2.49e-243	680.0	COG0499@1|root,COG0499@2|Bacteria,2GK2Q@201174|Actinobacteria,4D0FJ@85004|Bifidobacteriales	201174|Actinobacteria	H	S-adenosyl-L-homocysteine hydrolase, NAD binding domain	-	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
IOLKFBCL_01666	1437610.BREU_0653	1.91e-301	825.0	COG0402@1|root,COG0402@2|Bacteria,2HXRT@201174|Actinobacteria,4CZYF@85004|Bifidobacteriales	201174|Actinobacteria	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
IOLKFBCL_01667	1435051.BMOU_1746	7.06e-86	255.0	COG3542@1|root,COG3542@2|Bacteria,2IFG5@201174|Actinobacteria,4D0WA@85004|Bifidobacteriales	201174|Actinobacteria	S	Cupin superfamily (DUF985)	-	-	-	ko:K09705	-	-	-	-	ko00000	-	-	-	Cupin_5,DUF952
IOLKFBCL_01668	1437610.BREU_0651	6.76e-163	461.0	COG0834@1|root,COG0834@2|Bacteria,2GN3G@201174|Actinobacteria,4CZ9E@85004|Bifidobacteriales	201174|Actinobacteria	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	ko:K02030,ko:K02424,ko:K17073	ko02010,map02010	M00234,M00236,M00589	-	-	ko00000,ko00001,ko00002,ko02000,ko02035	3.A.1.3,3.A.1.3.10,3.A.1.3.14,3.A.1.3.20	-	-	SBP_bac_3
IOLKFBCL_01669	1435051.BMOU_1744	3.2e-161	458.0	COG0765@1|root,COG0765@2|Bacteria,2GM0I@201174|Actinobacteria,4D010@85004|Bifidobacteriales	201174|Actinobacteria	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
IOLKFBCL_01670	158787.BSCA_1190	2.57e-153	434.0	COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria,4CZ92@85004|Bifidobacteriales	201174|Actinobacteria	E	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	3.6.3.21	ko:K02028,ko:K02029	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
IOLKFBCL_01671	326426.Bbr_0584	0.0	983.0	COG0034@1|root,COG0034@2|Bacteria,2GK6I@201174|Actinobacteria,4CZ89@85004|Bifidobacteriales	201174|Actinobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	GO:0008150,GO:0040007	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
IOLKFBCL_01672	326426.Bbr_0583	6.44e-240	660.0	COG0150@1|root,COG0150@2|Bacteria,2GJNY@201174|Actinobacteria,4CZ3K@85004|Bifidobacteriales	201174|Actinobacteria	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016874,GO:0016879,GO:0016882,GO:0044424,GO:0044444,GO:0044464	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
IOLKFBCL_01673	216816.GS08_02945	1.15e-297	813.0	COG0151@1|root,COG0151@2|Bacteria,2I2F5@201174|Actinobacteria,4CZ3I@85004|Bifidobacteriales	201174|Actinobacteria	F	Belongs to the GARS family	purD	GO:0008150,GO:0040007	6.3.3.1,6.3.4.13	ko:K01945,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04208	RC00090,RC00166,RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
IOLKFBCL_01674	216816.GS08_02940	0.0	952.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4CZQF@85004|Bifidobacteriales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	aldH	-	1.2.1.3,1.2.99.10	ko:K00128,ko:K22445	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
IOLKFBCL_01675	216816.GS08_02935	0.0	1283.0	COG1368@1|root,COG1368@2|Bacteria,2HVID@201174|Actinobacteria,4CZ6J@85004|Bifidobacteriales	201174|Actinobacteria	M	Psort location CytoplasmicMembrane, score 9.26	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
IOLKFBCL_01676	326426.Bbr_0579	9.67e-200	555.0	COG0803@1|root,COG0803@2|Bacteria,2GM1K@201174|Actinobacteria,4CZ99@85004|Bifidobacteriales	201174|Actinobacteria	P	Zinc-uptake complex component A periplasmic	-	-	-	ko:K02077	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
IOLKFBCL_01677	1437610.BREU_0686	1.13e-127	370.0	COG0523@1|root,COG0523@2|Bacteria,2IB0E@201174|Actinobacteria,4CZVU@85004|Bifidobacteriales	201174|Actinobacteria	S	cobalamin synthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01678	1437610.BREU_0687	8.31e-40	132.0	COG0227@1|root,COG0227@2|Bacteria,2IQAT@201174|Actinobacteria,4D18M@85004|Bifidobacteriales	201174|Actinobacteria	J	Ribosomal L28 family	rpmB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
IOLKFBCL_01679	158787.BSCA_2086	5.79e-28	101.0	COG0267@1|root,COG0267@2|Bacteria,2GQFV@201174|Actinobacteria,4D1IA@85004|Bifidobacteriales	201174|Actinobacteria	J	Ribosomal protein L33	rpmG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
IOLKFBCL_01680	1437610.BREU_0689	1.24e-58	182.0	COG0199@1|root,COG0199@2|Bacteria,2IKN9@201174|Actinobacteria,4D12X@85004|Bifidobacteriales	201174|Actinobacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
IOLKFBCL_01681	77635.BISU_0570	1.72e-45	147.0	COG0254@1|root,COG0254@2|Bacteria,2IQ4I@201174|Actinobacteria,4D18J@85004|Bifidobacteriales	201174|Actinobacteria	J	Ribosomal protein L31	rpmE2	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
IOLKFBCL_01682	158787.BSCA_2089	4.34e-21	82.8	COG0257@1|root,COG0257@2|Bacteria,2GWN0@201174|Actinobacteria,4D1R1@85004|Bifidobacteriales	201174|Actinobacteria	J	Ribosomal protein L36	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
IOLKFBCL_01683	1437610.BREU_0691	1.55e-27	100.0	2B5DR@1|root,31Y86@2|Bacteria,2HZRT@201174|Actinobacteria,4D1FD@85004|Bifidobacteriales	201174|Actinobacteria	J	Ribosomal L32p protein family	-	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
IOLKFBCL_01684	158787.BSCA_2091	1.17e-23	102.0	COG0803@1|root,COG3443@1|root,COG0803@2|Bacteria,COG3443@2|Bacteria,2GM1K@201174|Actinobacteria,4D07D@85004|Bifidobacteriales	201174|Actinobacteria	P	ZinT (YodA) periplasmic lipocalin-like zinc-recruitment	-	-	-	ko:K02077,ko:K09815	ko02010,map02010	M00242,M00244	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ZinT,ZnuA
IOLKFBCL_01685	326426.Bbr_0575	1.89e-254	699.0	COG0701@1|root,COG0701@2|Bacteria,2GJQ0@201174|Actinobacteria,4D057@85004|Bifidobacteriales	201174|Actinobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
IOLKFBCL_01686	326426.Bbr_0574	2.69e-178	496.0	COG3689@1|root,COG3689@2|Bacteria,2I8JS@201174|Actinobacteria,4CZZQ@85004|Bifidobacteriales	201174|Actinobacteria	S	TIGRFAM TIGR03943 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1980
IOLKFBCL_01687	326426.Bbr_0573	8.39e-73	220.0	COG0735@1|root,COG0735@2|Bacteria,2IKS3@201174|Actinobacteria,4D15A@85004|Bifidobacteriales	201174|Actinobacteria	P	Ferric uptake regulator family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
IOLKFBCL_01688	326426.Bbr_0572	3.43e-85	250.0	2AUUP@1|root,31KHW@2|Bacteria,2IKU9@201174|Actinobacteria,4D15K@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01689	158787.BSCA_2101	6.6e-58	183.0	COG1309@1|root,COG1309@2|Bacteria,2HZJ5@201174|Actinobacteria,4D0MY@85004|Bifidobacteriales	201174|Actinobacteria	K	Transcriptional regulator C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
IOLKFBCL_01690	1437608.BBIA_0566	5.88e-90	268.0	COG1136@1|root,COG1136@2|Bacteria,2GJQV@201174|Actinobacteria,4CYT2@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IOLKFBCL_01692	158787.BSCA_2103	2.45e-59	206.0	COG0577@1|root,COG1511@1|root,COG0577@2|Bacteria,COG1511@2|Bacteria,2I2FK@201174|Actinobacteria,4CZJR@85004|Bifidobacteriales	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
IOLKFBCL_01693	326426.Bbr_0569	7.7e-95	276.0	COG0735@1|root,COG0735@2|Bacteria,2IKS3@201174|Actinobacteria,4D0XG@85004|Bifidobacteriales	201174|Actinobacteria	P	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
IOLKFBCL_01694	216816.GS08_02915	4.92e-286	781.0	COG0026@1|root,COG0026@2|Bacteria,2GJCU@201174|Actinobacteria,4CYWP@85004|Bifidobacteriales	201174|Actinobacteria	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
IOLKFBCL_01695	326426.Bbr_0567	8.44e-111	319.0	COG0041@1|root,COG0041@2|Bacteria,2IFFD@201174|Actinobacteria,4CYQZ@85004|Bifidobacteriales	201174|Actinobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	GO:0008150,GO:0040007	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3275c	AIRC
IOLKFBCL_01696	216816.GS08_02905	6.77e-223	616.0	COG0604@1|root,COG0604@2|Bacteria,2GMHR@201174|Actinobacteria,4D00X@85004|Bifidobacteriales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	yogA	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
IOLKFBCL_01697	216816.GS08_02900	0.0	1185.0	COG1154@1|root,COG1154@2|Bacteria,2GMFA@201174|Actinobacteria,4CZ2M@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0008661,GO:0009058,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030145,GO:0030975,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901363,GO:1901576,GO:1901681	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
IOLKFBCL_01698	216816.GS08_02895	0.0	890.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,2GIRW@201174|Actinobacteria,4CZMQ@85004|Bifidobacteriales	201174|Actinobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
IOLKFBCL_01699	216816.GS08_02890	4.06e-185	525.0	COG1361@1|root,COG1361@2|Bacteria,2GP6I@201174|Actinobacteria,4D013@85004|Bifidobacteriales	201174|Actinobacteria	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01700	216816.GS08_02885	3.61e-157	444.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4D2SJ@85004|Bifidobacteriales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	GO:0008150,GO:0009405,GO:0009605,GO:0009607,GO:0043207,GO:0044403,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136	-	ko:K02003,ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,FtsX
IOLKFBCL_01703	216816.GS08_02875	5.97e-267	733.0	COG2865@1|root,COG2865@2|Bacteria,2IBZQ@201174|Actinobacteria,4D03J@85004|Bifidobacteriales	201174|Actinobacteria	K	Putative ATP-dependent DNA helicase recG C-terminal	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4,HTH_27
IOLKFBCL_01704	216816.GS08_02870	8.77e-203	561.0	COG1737@1|root,COG1737@2|Bacteria,2HY2W@201174|Actinobacteria,4D050@85004|Bifidobacteriales	201174|Actinobacteria	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
IOLKFBCL_01705	216816.GS08_02865	0.0	1452.0	COG3534@1|root,COG3534@2|Bacteria,2GP9Z@201174|Actinobacteria,4CZ95@85004|Bifidobacteriales	201174|Actinobacteria	G	Alpha-L-arabinofuranosidase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-L-AF_C,Big_3_5,CBM_4_9,DUF1349,Laminin_G_3
IOLKFBCL_01706	216816.GS08_02860	2.01e-48	155.0	2B4W6@1|root,31XNV@2|Bacteria,2GZB9@201174|Actinobacteria,4D1T7@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01707	216816.GS08_02855	2.61e-19	86.7	COG1055@1|root,COG1055@2|Bacteria,2GP6U@201174|Actinobacteria,4CZ37@85004|Bifidobacteriales	201174|Actinobacteria	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
IOLKFBCL_01708	216816.GS08_02840	0.0	931.0	COG1167@1|root,COG1167@2|Bacteria,2GITW@201174|Actinobacteria,4CZGJ@85004|Bifidobacteriales	201174|Actinobacteria	EK	Alanine-glyoxylate amino-transferase	-	-	-	ko:K03710,ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000,ko03000	-	-	-	Aminotran_1_2,GntR
IOLKFBCL_01709	216816.GS08_02835	4.17e-149	419.0	COG0311@1|root,COG0311@2|Bacteria,2GNYG@201174|Actinobacteria,4CYUS@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
IOLKFBCL_01710	326426.Bbr_0549	1.9e-198	551.0	COG0214@1|root,COG0214@2|Bacteria,2GK1T@201174|Actinobacteria,4CZ5P@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
IOLKFBCL_01711	216816.GS08_02825	0.0	1377.0	COG0358@1|root,COG0358@2|Bacteria,2GJFX@201174|Actinobacteria,4CYZG@85004|Bifidobacteriales	201174|Actinobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_4,Toprim_N,zf-CHC2
IOLKFBCL_01712	216816.GS08_02820	4.87e-313	852.0	COG0232@1|root,COG0232@2|Bacteria,2GJ8F@201174|Actinobacteria,4CYYP@85004|Bifidobacteriales	201174|Actinobacteria	F	Phosphohydrolase-associated domain	dgt	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
IOLKFBCL_01713	216816.GS08_02815	2.12e-315	860.0	COG0787@1|root,COG0787@2|Bacteria,2GM2Y@201174|Actinobacteria,4CZ2Q@85004|Bifidobacteriales	201174|Actinobacteria	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
IOLKFBCL_01714	216816.GS08_02810	0.0	940.0	COG0531@1|root,COG0531@2|Bacteria,2GJ75@201174|Actinobacteria,4CYZA@85004|Bifidobacteriales	201174|Actinobacteria	E	aromatic amino acid transport protein AroP K03293	aap1	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
IOLKFBCL_01715	216816.GS08_02805	1.45e-131	372.0	COG1670@1|root,COG1670@2|Bacteria,2HBE2@201174|Actinobacteria,4CZTR@85004|Bifidobacteriales	201174|Actinobacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	cysE	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01716	216816.GS08_02800	2.77e-119	340.0	COG1854@1|root,COG1854@2|Bacteria,2GJVF@201174|Actinobacteria,4CYZ4@85004|Bifidobacteriales	201174|Actinobacteria	H	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)	luxS	-	4.4.1.21	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	M00609	R01291	RC00069,RC01929	ko00000,ko00001,ko00002,ko01000	-	-	-	LuxS
IOLKFBCL_01717	216816.GS08_02795	0.0	1263.0	COG0514@1|root,COG0514@2|Bacteria,2GJSS@201174|Actinobacteria,4CZ0I@85004|Bifidobacteriales	201174|Actinobacteria	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
IOLKFBCL_01718	216816.GS08_02790	0.0	1035.0	COG1376@1|root,COG1376@2|Bacteria,2GQ7D@201174|Actinobacteria,4CZ5A@85004|Bifidobacteriales	201174|Actinobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
IOLKFBCL_01719	216816.GS08_02785	1.84e-282	772.0	COG0626@1|root,COG0626@2|Bacteria,2GJ5S@201174|Actinobacteria,4CYY2@85004|Bifidobacteriales	201174|Actinobacteria	E	Cys/Met metabolism PLP-dependent enzyme	metB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1079	Cys_Met_Meta_PP
IOLKFBCL_01720	216816.GS08_02780	1.17e-118	347.0	COG0031@1|root,COG0031@2|Bacteria,2GIXE@201174|Actinobacteria,4CYQ4@85004|Bifidobacteriales	201174|Actinobacteria	E	Pyridoxal-phosphate dependent enzyme	cbs	GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0016020,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363	2.5.1.47,4.2.1.22	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00035,M00338	R00891,R00897,R01290,R03601,R04859,R04942	RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
IOLKFBCL_01721	1232436.CAPF01000043_gene330	0.000141	47.0	COG0402@1|root,COG0402@2|Bacteria,2GM63@201174|Actinobacteria,4CV60@84998|Coriobacteriia	84998|Coriobacteriia	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
IOLKFBCL_01722	401473.BDP_2025	7.91e-225	633.0	COG0477@1|root,COG0477@2|Bacteria,2GJV6@201174|Actinobacteria,4CZH3@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	ko:K08168	-	M00704	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.3.16,2.A.1.3.22,2.A.1.3.6	-	-	MFS_1
IOLKFBCL_01723	1437600.JDUI01000011_gene698	8.01e-193	539.0	COG1957@1|root,COG1957@2|Bacteria,2GP6N@201174|Actinobacteria,4CZ0Y@85004|Bifidobacteriales	201174|Actinobacteria	F	Inosine-uridine preferring nucleoside hydrolase	iunH2	-	3.2.2.1	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
IOLKFBCL_01725	216816.GS08_02770	3.28e-154	439.0	COG0444@1|root,COG0444@2|Bacteria,2GIXV@201174|Actinobacteria,4CZ3U@85004|Bifidobacteriales	201174|Actinobacteria	EP	oligopeptide transport protein of the ABC superfamily, ATP-binding component	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran
IOLKFBCL_01726	216816.GS08_02765	1.71e-180	508.0	COG1173@1|root,COG1173@2|Bacteria,2GNQ5@201174|Actinobacteria,4CZ84@85004|Bifidobacteriales	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
IOLKFBCL_01727	216816.GS08_02760	1.38e-206	574.0	COG0601@1|root,COG0601@2|Bacteria,2GK0Z@201174|Actinobacteria,4CYST@85004|Bifidobacteriales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
IOLKFBCL_01728	216816.GS08_02755	0.0	1033.0	COG0747@1|root,COG0747@2|Bacteria,2GJ4B@201174|Actinobacteria,4CYWF@85004|Bifidobacteriales	201174|Actinobacteria	E	ABC transporter, substrate-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
IOLKFBCL_01729	216816.GS08_02750	1.38e-308	842.0	COG0452@1|root,COG0452@2|Bacteria,2GJGJ@201174|Actinobacteria,4D0GJ@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	GO:0003674,GO:0003824,GO:0004633,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
IOLKFBCL_01730	216816.GS08_02745	4.65e-181	504.0	COG1521@1|root,COG1521@2|Bacteria,2GMRQ@201174|Actinobacteria,4CZQS@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
IOLKFBCL_01731	216816.GS08_02740	0.0	913.0	COG1653@1|root,COG1653@2|Bacteria,2GJIP@201174|Actinobacteria,4CYRE@85004|Bifidobacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
IOLKFBCL_01732	326426.Bbr_0529	0.0	1386.0	COG1874@1|root,COG1874@2|Bacteria,2GMDT@201174|Actinobacteria,4CZ38@85004|Bifidobacteriales	201174|Actinobacteria	G	Psort location Cytoplasmic, score 8.87	bga1	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
IOLKFBCL_01733	216816.GS08_02685	7.33e-143	407.0	COG0564@1|root,COG0564@2|Bacteria,2GJ2Z@201174|Actinobacteria,4CZB2@85004|Bifidobacteriales	201174|Actinobacteria	J	RNA pseudouridylate synthase	-	-	5.4.99.28,5.4.99.29	ko:K06177	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
IOLKFBCL_01734	216816.GS08_02680	0.0	1229.0	COG0449@1|root,COG0449@2|Bacteria,2GKH0@201174|Actinobacteria,4CZ1G@85004|Bifidobacteriales	201174|Actinobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iNJ661.Rv3436c	GATase_6,SIS
IOLKFBCL_01735	216816.GS08_02675	2.91e-190	529.0	COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria,4CZSB@85004|Bifidobacteriales	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	tcyC	-	3.6.3.21	ko:K02028,ko:K02029	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
IOLKFBCL_01736	326426.Bbr_0522	2.85e-218	604.0	COG0765@1|root,COG0765@2|Bacteria,2GJJ9@201174|Actinobacteria,4CYSN@85004|Bifidobacteriales	201174|Actinobacteria	E	Binding-protein-dependent transport system inner membrane component	yecS	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
IOLKFBCL_01737	216816.GS08_02665	6.22e-216	597.0	COG0834@1|root,COG0834@2|Bacteria,2GJQW@201174|Actinobacteria,4CZ6H@85004|Bifidobacteriales	201174|Actinobacteria	ET	ABC transporter, substrate-binding protein, family 3	glnH	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
IOLKFBCL_01738	216816.GS08_02660	1.4e-213	591.0	COG0834@1|root,COG0834@2|Bacteria,2GJQW@201174|Actinobacteria,4CZ6H@85004|Bifidobacteriales	201174|Actinobacteria	ET	ABC transporter, substrate-binding protein, family 3	glnH	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
IOLKFBCL_01739	216816.GS08_02655	8.01e-107	308.0	COG0691@1|root,COG0691@2|Bacteria,2GJX1@201174|Actinobacteria,4CZG4@85004|Bifidobacteriales	201174|Actinobacteria	J	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
IOLKFBCL_01740	216816.GS08_02650	5.86e-263	728.0	COG3942@1|root,COG3942@2|Bacteria,2GZG8@201174|Actinobacteria,4CYQJ@85004|Bifidobacteriales	201174|Actinobacteria	D	CHAP domain protein	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	CHAP
IOLKFBCL_01741	216816.GS08_02645	3.68e-204	566.0	COG2177@1|root,COG2177@2|Bacteria,2GJMA@201174|Actinobacteria,4CZSQ@85004|Bifidobacteriales	201174|Actinobacteria	D	Part of the ABC transporter FtsEX involved in cellular division	ftsX	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
IOLKFBCL_01742	216816.GS08_02640	2.61e-234	650.0	COG2884@1|root,COG2884@2|Bacteria,2GJE1@201174|Actinobacteria,4CYYQ@85004|Bifidobacteriales	201174|Actinobacteria	D	Cell division ATP-binding protein FtsE	ftsE	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
IOLKFBCL_01743	216816.GS08_02635	3.59e-263	721.0	COG1186@1|root,COG1186@2|Bacteria,2GJ0F@201174|Actinobacteria,4CZJX@85004|Bifidobacteriales	201174|Actinobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
IOLKFBCL_01744	216816.GS08_02630	0.0	881.0	COG1373@1|root,COG1373@2|Bacteria,2HJ52@201174|Actinobacteria,4D2TQ@85004|Bifidobacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
IOLKFBCL_01745	216816.GS08_02625	0.0	961.0	COG0847@1|root,COG0847@2|Bacteria,2IC59@201174|Actinobacteria,4CZY1@85004|Bifidobacteriales	201174|Actinobacteria	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01746	216816.GS08_02620	1.07e-158	444.0	COG0242@1|root,COG0242@2|Bacteria,2GNZ9@201174|Actinobacteria,4CZ7M@85004|Bifidobacteriales	201174|Actinobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
IOLKFBCL_01747	216816.GS08_02615	0.0	887.0	COG1109@1|root,COG1109@2|Bacteria,2GN87@201174|Actinobacteria,4CYZX@85004|Bifidobacteriales	201174|Actinobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	GO:0008150,GO:0040007	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
IOLKFBCL_01748	216816.GS08_03170	4.07e-131	382.0	COG1175@1|root,COG1175@2|Bacteria,2GKJI@201174|Actinobacteria,4D0GQ@85004|Bifidobacteriales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K05814	ko02010,map02010	M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3	-	-	BPD_transp_1
IOLKFBCL_01749	216816.GS08_03165	7.79e-124	360.0	COG0395@1|root,COG0395@2|Bacteria,2GMTH@201174|Actinobacteria,4D29F@85004|Bifidobacteriales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026,ko:K05815	ko02010,map02010	M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3	-	-	BPD_transp_1
IOLKFBCL_01750	216816.GS08_03160	2.99e-200	568.0	COG1653@1|root,COG1653@2|Bacteria,2HP0P@201174|Actinobacteria	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K05813	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	SBP_bac_8
IOLKFBCL_01751	216816.GS08_03155	2.94e-126	368.0	COG0584@1|root,COG0584@2|Bacteria,2INE1@201174|Actinobacteria	201174|Actinobacteria	C	Domain of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	DUF4996,GDPD
IOLKFBCL_01752	216816.GS08_02585	0.0	1703.0	COG0308@1|root,COG0308@2|Bacteria,2GJJ4@201174|Actinobacteria,4CZH4@85004|Bifidobacteriales	201174|Actinobacteria	E	Peptidase family M1 domain	pepN	-	3.4.11.2	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
IOLKFBCL_01753	216816.GS08_02580	0.0	1211.0	COG0595@1|root,COG0595@2|Bacteria,2GIW7@201174|Actinobacteria,4CZEJ@85004|Bifidobacteriales	201174|Actinobacteria	J	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
IOLKFBCL_01754	216816.GS08_02575	8.94e-213	588.0	COG0329@1|root,COG0329@2|Bacteria,2GJ34@201174|Actinobacteria,4CZ34@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
IOLKFBCL_01755	216816.GS08_02570	1.26e-167	469.0	COG0289@1|root,COG0289@2|Bacteria,2GM2T@201174|Actinobacteria,4CZJ5@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
IOLKFBCL_01756	216816.GS08_02565	6.14e-297	812.0	COG2271@1|root,COG2271@2|Bacteria,2I2GK@201174|Actinobacteria,4CZ0T@85004|Bifidobacteriales	201174|Actinobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
IOLKFBCL_01757	216816.GS08_02560	0.0	2521.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2GM2E@201174|Actinobacteria,4CZ49@85004|Bifidobacteriales	201174|Actinobacteria	L	Belongs to the helicase family. UvrD subfamily	uvrD2	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
IOLKFBCL_01758	216816.GS08_02555	0.0	2574.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2GJD0@201174|Actinobacteria,4CYQU@85004|Bifidobacteriales	201174|Actinobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	AAA_19,PDDEXK_1,UvrD-helicase,UvrD_C
IOLKFBCL_01759	216816.GS08_02550	0.0	917.0	COG0515@1|root,COG0515@2|Bacteria,2GIW5@201174|Actinobacteria,4CZ9N@85004|Bifidobacteriales	201174|Actinobacteria	KLT	Protein tyrosine kinase	pknK	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
IOLKFBCL_01760	216816.GS08_02545	0.0	3615.0	COG4733@1|root,COG4733@2|Bacteria,2GMKC@201174|Actinobacteria,4CZFT@85004|Bifidobacteriales	201174|Actinobacteria	S	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
IOLKFBCL_01761	216816.GS08_02540	3.15e-233	654.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4CZ3M@85004|Bifidobacteriales	201174|Actinobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
IOLKFBCL_01762	216816.GS08_02535	2.52e-282	773.0	COG1721@1|root,COG1721@2|Bacteria,2GIWE@201174|Actinobacteria,4CZWT@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
IOLKFBCL_01763	216816.GS08_02530	0.0	1541.0	COG1305@1|root,COG1305@2|Bacteria,2HQBB@201174|Actinobacteria,4CZ3X@85004|Bifidobacteriales	201174|Actinobacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
IOLKFBCL_01764	216816.GS08_02525	1.54e-05	46.2	COG0631@1|root,COG0631@2|Bacteria,2GJ3M@201174|Actinobacteria,4CZNH@85004|Bifidobacteriales	201174|Actinobacteria	T	Sigma factor PP2C-like phosphatases	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	BofC_C,PP2C,PP2C_2
IOLKFBCL_01765	216816.GS08_02525	1.05e-31	118.0	COG0631@1|root,COG0631@2|Bacteria,2GJ3M@201174|Actinobacteria,4CZNH@85004|Bifidobacteriales	201174|Actinobacteria	T	Sigma factor PP2C-like phosphatases	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	BofC_C,PP2C,PP2C_2
IOLKFBCL_01766	216816.GS08_02520	1.44e-100	296.0	COG5602@1|root,COG5602@2|Bacteria,2GRHT@201174|Actinobacteria,4D0W6@85004|Bifidobacteriales	201174|Actinobacteria	B	Belongs to the OprB family	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01767	216816.GS08_02515	8.85e-117	337.0	COG1716@1|root,COG1716@2|Bacteria,2IIXF@201174|Actinobacteria,4D0UU@85004|Bifidobacteriales	201174|Actinobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
IOLKFBCL_01768	216816.GS08_02450	0.0	2547.0	COG0086@1|root,COG0086@2|Bacteria,2GKWF@201174|Actinobacteria,4CZ1D@85004|Bifidobacteriales	201174|Actinobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
IOLKFBCL_01769	216816.GS08_02445	0.0	2362.0	COG0085@1|root,COG0085@2|Bacteria,2GJ81@201174|Actinobacteria,4CZ3W@85004|Bifidobacteriales	201174|Actinobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
IOLKFBCL_01770	216816.GS08_02440	2.14e-149	422.0	2E5CN@1|root,3304R@2|Bacteria,2I2GJ@201174|Actinobacteria,4D0SD@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01771	216816.GS08_02435	2.52e-235	646.0	COG1194@1|root,COG1194@2|Bacteria,2GJD9@201174|Actinobacteria,4CYRB@85004|Bifidobacteriales	201174|Actinobacteria	L	FES	mutY	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
IOLKFBCL_01772	398513.BBNG_00323	9.47e-149	419.0	COG0219@1|root,COG0219@2|Bacteria,2IHN9@201174|Actinobacteria,4CZ0E@85004|Bifidobacteriales	201174|Actinobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily	spoU	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
IOLKFBCL_01773	33905.BTHE_0898	3.82e-52	164.0	COG2026@1|root,COG2026@2|Bacteria,2GSVC@201174|Actinobacteria,4D1NW@85004|Bifidobacteriales	201174|Actinobacteria	DJ	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
IOLKFBCL_01774	33905.BTHE_0899	1.28e-45	147.0	COG4710@1|root,COG4710@2|Bacteria,2GSB2@201174|Actinobacteria,4D1HJ@85004|Bifidobacteriales	201174|Actinobacteria	S	CopG domain protein DNA-binding domain protein	-	-	-	ko:K18918	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	-
IOLKFBCL_01776	1134445.AJJM01000052_gene2080	1.27e-24	104.0	COG2977@1|root,COG2977@2|Bacteria,2IIA2@201174|Actinobacteria	201174|Actinobacteria	Q	Belongs to the P-Pant transferase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	ACPS
IOLKFBCL_01777	78346.BRUM_1573	3.38e-159	464.0	COG0477@1|root,COG2814@2|Bacteria,2GJF6@201174|Actinobacteria,4CZW6@85004|Bifidobacteriales	201174|Actinobacteria	U	Sugar (and other) transporter	-	-	-	ko:K08369	-	-	-	-	ko00000,ko02000	2.A.1	-	-	MFS_1,MFS_2,Sugar_tr
IOLKFBCL_01778	1680.BADO_1346	2.08e-284	777.0	COG1181@1|root,COG1181@2|Bacteria,2I2GF@201174|Actinobacteria,4D0FN@85004|Bifidobacteriales	201174|Actinobacteria	M	Belongs to the D-alanine--D-alanine ligase family	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01779	1357272.AVEO02000052_gene1154	1.68e-26	124.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,1RPAG@1236|Gammaproteobacteria,1Z6M8@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	Q	COG1020 Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
IOLKFBCL_01780	1123321.KB905817_gene5221	1.25e-41	163.0	COG1020@1|root,COG3321@1|root,COG1020@2|Bacteria,COG3321@2|Bacteria,2GISR@201174|Actinobacteria	201174|Actinobacteria	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	ko:K13611,ko:K13614	-	-	-	-	ko00000,ko01004,ko01008	-	-	-	AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,Thioesterase,ketoacyl-synt
IOLKFBCL_01781	1680.BADO_1345	8.02e-277	759.0	COG0477@1|root,COG2814@2|Bacteria,2IFA0@201174|Actinobacteria,4D0EP@85004|Bifidobacteriales	201174|Actinobacteria	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
IOLKFBCL_01782	78346.BRUM_0033	5.65e-51	173.0	COG1672@1|root,COG1672@2|Bacteria,2GMAZ@201174|Actinobacteria,4CZTD@85004|Bifidobacteriales	201174|Actinobacteria	S	ATPase domain predominantly from Archaea	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	ATPase_2,DUF234
IOLKFBCL_01783	78346.BRUM_0033	7.8e-29	113.0	COG1672@1|root,COG1672@2|Bacteria,2GMAZ@201174|Actinobacteria,4CZTD@85004|Bifidobacteriales	201174|Actinobacteria	S	ATPase domain predominantly from Archaea	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	ATPase_2,DUF234
IOLKFBCL_01784	78346.BRUM_0033	4.31e-168	483.0	COG1672@1|root,COG1672@2|Bacteria,2GMAZ@201174|Actinobacteria,4CZTD@85004|Bifidobacteriales	201174|Actinobacteria	S	ATPase domain predominantly from Archaea	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	ATPase_2,DUF234
IOLKFBCL_01785	216816.GS08_02425	0.0	874.0	COG2848@1|root,COG2848@2|Bacteria,2HHMF@201174|Actinobacteria,4CZGB@85004|Bifidobacteriales	201174|Actinobacteria	S	UPF0210 protein	-	-	-	ko:K09157	-	-	-	-	ko00000	-	-	-	DUF711
IOLKFBCL_01786	216816.GS08_02420	1.13e-58	181.0	COG3830@1|root,COG3830@2|Bacteria,2IKS1@201174|Actinobacteria,4D11D@85004|Bifidobacteriales	201174|Actinobacteria	T	Belongs to the UPF0237 family	-	-	-	ko:K07166	-	-	-	-	ko00000	-	-	-	ACT_6
IOLKFBCL_01787	216816.GS08_02415	0.0	1333.0	COG1621@1|root,COG1621@2|Bacteria,2GJ9T@201174|Actinobacteria,4CZ8W@85004|Bifidobacteriales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 32 family	-	-	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32N
IOLKFBCL_01788	216816.GS08_02410	9.48e-242	666.0	COG1609@1|root,COG1609@2|Bacteria,2GJY9@201174|Actinobacteria,4CYU5@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
IOLKFBCL_01789	216816.GS08_02405	3.11e-130	373.0	COG5578@1|root,COG5578@2|Bacteria,2H1AM@201174|Actinobacteria,4CYSQ@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function, DUF624	-	-	-	-	-	-	-	-	-	-	-	-	DUF624
IOLKFBCL_01790	216816.GS08_02400	2.26e-216	598.0	COG0395@1|root,COG0395@2|Bacteria,2GJPQ@201174|Actinobacteria,4CYTJ@85004|Bifidobacteriales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17320	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
IOLKFBCL_01791	216816.GS08_02395	1.14e-218	604.0	COG4209@1|root,COG4209@2|Bacteria,2GKSR@201174|Actinobacteria,4CZIC@85004|Bifidobacteriales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17319	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
IOLKFBCL_01792	1680.BADO_1396	2.67e-111	333.0	COG1653@1|root,COG1653@2|Bacteria,2I8SG@201174|Actinobacteria,4CZ4S@85004|Bifidobacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K17318	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	SBP_bac_1,SBP_bac_8
IOLKFBCL_01793	216816.GS08_02390	5.28e-204	575.0	COG1653@1|root,COG1653@2|Bacteria,2I8SG@201174|Actinobacteria,4CZ4S@85004|Bifidobacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K17318	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	SBP_bac_1,SBP_bac_8
IOLKFBCL_01794	762211.BSTEL_1427	1.65e-267	745.0	COG0477@1|root,COG2814@2|Bacteria,2GIZX@201174|Actinobacteria,4CZWX@85004|Bifidobacteriales	201174|Actinobacteria	U	Drug resistance MFS transporter, drug H antiporter-2 family	-	-	-	ko:K18926	-	M00715	-	-	ko00000,ko00002,ko02000	2.A.1.3.30	-	-	CBS,MFS_1
IOLKFBCL_01795	326426.Bbr_0492	2.92e-297	811.0	COG0153@1|root,COG0153@2|Bacteria,2GJXI@201174|Actinobacteria,4CZNV@85004|Bifidobacteriales	201174|Actinobacteria	G	Belongs to the GHMP kinase family. GalK subfamily	galK	-	2.7.1.6,2.7.7.12	ko:K00849,ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955,R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
IOLKFBCL_01796	216816.GS08_02370	0.0	866.0	COG1085@1|root,COG1085@2|Bacteria,2I2DM@201174|Actinobacteria,4CYXZ@85004|Bifidobacteriales	201174|Actinobacteria	C	Galactose-1-phosphate uridyl transferase, N-terminal domain	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
IOLKFBCL_01797	216816.GS08_02365	1.03e-157	444.0	COG1349@1|root,COG1349@2|Bacteria,2H5X4@201174|Actinobacteria,4CZMT@85004|Bifidobacteriales	201174|Actinobacteria	K	DeoR C terminal sensor domain	-	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
IOLKFBCL_01798	216816.GS08_02360	1.71e-286	781.0	COG0167@1|root,COG0167@2|Bacteria,2GKC6@201174|Actinobacteria,4CYWW@85004|Bifidobacteriales	201174|Actinobacteria	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.3.5.2,1.3.98.1	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01867,R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
IOLKFBCL_01799	216816.GS08_02355	9.1e-317	864.0	COG1902@1|root,COG1902@2|Bacteria,2GK8E@201174|Actinobacteria,4CZ9Z@85004|Bifidobacteriales	201174|Actinobacteria	C	NADH:flavin oxidoreductase / NADH oxidase family	namA	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
IOLKFBCL_01800	216816.GS08_02350	0.0	1408.0	COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria,4CZAZ@85004|Bifidobacteriales	201174|Actinobacteria	M	Transglycosylase	pon1	-	-	-	-	-	-	-	-	-	-	-	PASTA,Transgly,Transpeptidase
IOLKFBCL_01801	216816.GS08_02345	1.23e-168	472.0	COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria,4CYYW@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn_helix, cAMP Regulatory protein	crp	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
IOLKFBCL_01802	216816.GS08_02340	2.12e-253	696.0	COG0095@1|root,COG0095@2|Bacteria,2GJV5@201174|Actinobacteria,4CZYA@85004|Bifidobacteriales	201174|Actinobacteria	H	Biotin/lipoate A/B protein ligase family	lplA	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
IOLKFBCL_01803	216816.GS08_02335	3.1e-246	676.0	COG0473@1|root,COG0473@2|Bacteria,2GK44@201174|Actinobacteria,4CZ08@85004|Bifidobacteriales	201174|Actinobacteria	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
IOLKFBCL_01804	216816.GS08_02330	0.0	1711.0	COG1770@1|root,COG1770@2|Bacteria,2GNA9@201174|Actinobacteria,4CZ2X@85004|Bifidobacteriales	201174|Actinobacteria	E	Peptidase, S9A B C family, catalytic domain protein	ptrB	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
IOLKFBCL_01805	216816.GS08_02325	0.0	870.0	COG4850@1|root,COG4850@2|Bacteria,2GKPS@201174|Actinobacteria,4CZ13@85004|Bifidobacteriales	201174|Actinobacteria	S	Uncharacterized conserved protein (DUF2183)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2183
IOLKFBCL_01806	216816.GS08_01780	5.99e-274	754.0	COG0675@1|root,COG0675@2|Bacteria,2GM6K@201174|Actinobacteria,4CZ11@85004|Bifidobacteriales	201174|Actinobacteria	L	Helix-turn-helix domain	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
IOLKFBCL_01807	216816.GS08_01775	1.12e-131	374.0	COG2452@1|root,COG2452@2|Bacteria,2IDNQ@201174|Actinobacteria,4CZVV@85004|Bifidobacteriales	201174|Actinobacteria	L	Resolvase, N terminal domain	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K07450	-	-	-	-	ko00000	-	-	-	Resolvase
IOLKFBCL_01808	216816.GS08_05975	9.48e-237	650.0	COG4823@1|root,COG4823@2|Bacteria,2HWAP@201174|Actinobacteria,4D0Z3@85004|Bifidobacteriales	201174|Actinobacteria	V	Abi-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abi_2
IOLKFBCL_01809	702459.BBPR_0778	1.77e-177	503.0	COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria,4D0DN@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase and inactivated derivatives IS30 family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
IOLKFBCL_01810	78344.BIGA_1749	4.57e-11	63.5	COG2963@1|root,COG3328@1|root,COG2963@2|Bacteria,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria,4D023@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
IOLKFBCL_01812	356829.BITS_1882	1.05e-07	54.7	2B29P@1|root,31UTG@2|Bacteria,2GUFB@201174|Actinobacteria,4D1HY@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01814	1121115.AXVN01000064_gene4029	1.71e-42	146.0	28NIV@1|root,2ZBK5@2|Bacteria,1V1U5@1239|Firmicutes,24FW5@186801|Clostridia,3XZXI@572511|Blautia	186801|Clostridia	S	Bacterial protein of unknown function (DUF961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF961
IOLKFBCL_01815	1235793.C809_00152	1.43e-96	281.0	2CI1N@1|root,3025Y@2|Bacteria,1V3PY@1239|Firmicutes,24G0H@186801|Clostridia,27JHG@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01816	742765.HMPREF9457_02042	6.99e-31	119.0	COG1674@1|root,COG1674@2|Bacteria,1TPHE@1239|Firmicutes,249WR@186801|Clostridia,27V96@189330|Dorea	186801|Clostridia	D	COG COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	FtsK_SpoIIIE
IOLKFBCL_01817	1437608.BBIA_0616	2.25e-192	545.0	COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria,4D0DN@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase and inactivated derivatives IS30 family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
IOLKFBCL_01818	525254.HMPREF0072_1942	2.44e-134	382.0	COG1136@1|root,COG1136@2|Bacteria,1V3NN@1239|Firmicutes,24I94@186801|Clostridia,22HGS@1570339|Peptoniphilaceae	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IOLKFBCL_01819	525254.HMPREF0072_1943	4.49e-145	415.0	COG4652@1|root,COG4652@2|Bacteria,1UYA7@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01820	525254.HMPREF0072_1944	4.19e-155	445.0	COG4652@1|root,COG4652@2|Bacteria,1UYA7@1239|Firmicutes,250QA@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01821	401473.BDP_1440	1.81e-30	119.0	COG0842@1|root,COG0842@2|Bacteria,2H9HW@201174|Actinobacteria,4CZ1J@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
IOLKFBCL_01822	332101.JIBU02000012_gene1073	3.66e-114	335.0	COG1131@1|root,COG1131@2|Bacteria,1TP4J@1239|Firmicutes,253U3@186801|Clostridia,36DP9@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter ATP-binding	mutF	-	-	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	M00254,M00817	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.124.1,3.A.1.124.2,3.A.1.124.6	-	-	ABC_tran
IOLKFBCL_01823	457412.RSAG_01608	1.28e-76	239.0	COG4200@1|root,COG4200@2|Bacteria,1V78D@1239|Firmicutes,25D9T@186801|Clostridia	186801|Clostridia	S	ABC-2 family transporter protein	mutE	-	-	ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	M00817	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.124.1,3.A.1.124.2,3.A.1.124.6	-	-	ABC2_membrane_4
IOLKFBCL_01824	1121115.AXVN01000067_gene3467	1.88e-73	231.0	COG4200@1|root,COG4200@2|Bacteria,1V4AY@1239|Firmicutes,24EXR@186801|Clostridia,3Y0KJ@572511|Blautia	186801|Clostridia	S	Lantibiotic protection ABC transporter permease subunit, MutG family	mutG	-	-	ko:K20492	ko02010,ko02020,ko02024,map02010,map02020,map02024	M00817	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.124.1,3.A.1.124.2,3.A.1.124.6	-	-	ABC2_membrane_4
IOLKFBCL_01825	1232447.BAHW02000002_gene32	1.13e-113	334.0	28JBR@1|root,2Z96E@2|Bacteria,1V0A1@1239|Firmicutes,24D16@186801|Clostridia	186801|Clostridia	-	-	-	-	-	ko:K20489	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001	-	-	-	-
IOLKFBCL_01826	1232447.BAHW02000002_gene31	2.79e-126	362.0	COG0745@1|root,COG0745@2|Bacteria,1TQ0D@1239|Firmicutes,248WX@186801|Clostridia,26APR@186813|unclassified Clostridiales	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K20488	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
IOLKFBCL_01827	411459.RUMOBE_02511	7.61e-145	427.0	COG0642@1|root,COG2205@2|Bacteria,1TS1G@1239|Firmicutes,248TF@186801|Clostridia,3Y01W@572511|Blautia	186801|Clostridia	T	subtilin biosynthesis sensor protein SpaK	-	-	2.7.13.3	ko:K20487	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
IOLKFBCL_01828	216816.GS08_05935	1.59e-129	379.0	2E39G@1|root,32Y91@2|Bacteria,2IMAD@201174|Actinobacteria,4D0XM@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01829	216816.GS08_05930	8.67e-205	568.0	COG0697@1|root,COG0697@2|Bacteria,2I8X5@201174|Actinobacteria,4D011@85004|Bifidobacteriales	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
IOLKFBCL_01830	326426.Bbr_1135	3.34e-92	269.0	COG3576@1|root,COG3576@2|Bacteria,2IJK2@201174|Actinobacteria,4D0W8@85004|Bifidobacteriales	201174|Actinobacteria	S	Pfam:Pyridox_oxidase	pdxH	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
IOLKFBCL_01831	216816.GS08_05920	7.16e-297	811.0	COG0742@1|root,COG0742@2|Bacteria,2HZAY@201174|Actinobacteria,4CZEU@85004|Bifidobacteriales	201174|Actinobacteria	L	ribosomal rna small subunit methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth95,Methyltransf_15,PCMT
IOLKFBCL_01832	216816.GS08_05915	1.31e-209	578.0	COG0406@1|root,COG0406@2|Bacteria,2GJYU@201174|Actinobacteria,4CZI8@85004|Bifidobacteriales	201174|Actinobacteria	G	Phosphoglycerate mutase family	gpmB	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0044237	3.1.3.85,5.4.2.11	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
IOLKFBCL_01833	216816.GS08_05910	1.16e-216	599.0	COG0598@1|root,COG0598@2|Bacteria,2HZ8V@201174|Actinobacteria,4CYWX@85004|Bifidobacteriales	201174|Actinobacteria	P	CorA-like Mg2+ transporter protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
IOLKFBCL_01834	216816.GS08_05905	1.56e-192	535.0	COG0834@1|root,COG0834@2|Bacteria,2I9PU@201174|Actinobacteria,4D09U@85004|Bifidobacteriales	201174|Actinobacteria	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	ko:K10005	ko02010,map02010	M00233	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.9	-	-	SBP_bac_3
IOLKFBCL_01835	216816.GS08_05900	0.0	2031.0	COG0495@1|root,COG0495@2|Bacteria,2GJI1@201174|Actinobacteria,4CZHV@85004|Bifidobacteriales	201174|Actinobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
IOLKFBCL_01836	216816.GS08_05895	1.05e-98	291.0	COG1555@1|root,COG1555@2|Bacteria,2IQDC@201174|Actinobacteria,4D176@85004|Bifidobacteriales	201174|Actinobacteria	L	Helix-hairpin-helix motif	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
IOLKFBCL_01837	216816.GS08_05890	0.0	982.0	COG0658@1|root,COG0658@2|Bacteria,2GJGR@201174|Actinobacteria,4CZ6X@85004|Bifidobacteriales	201174|Actinobacteria	S	Competence protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
IOLKFBCL_01838	216816.GS08_05885	2.48e-226	624.0	COG1466@1|root,COG1466@2|Bacteria,2GNMZ@201174|Actinobacteria,4CZ07@85004|Bifidobacteriales	201174|Actinobacteria	L	DNA polymerase III delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
IOLKFBCL_01839	216816.GS08_05880	9.29e-132	374.0	COG0802@1|root,COG0802@2|Bacteria,2IKV2@201174|Actinobacteria,4D0PH@85004|Bifidobacteriales	201174|Actinobacteria	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	tsaE	GO:0008150,GO:0040007	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
IOLKFBCL_01840	216816.GS08_05875	1.29e-191	532.0	COG1214@1|root,COG1214@2|Bacteria,2GMTM@201174|Actinobacteria,4D0A2@85004|Bifidobacteriales	201174|Actinobacteria	O	Glycoprotease family	yeaZ	GO:0002949,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0071944,GO:0090304,GO:1901360	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
IOLKFBCL_01841	216816.GS08_05870	1.52e-127	363.0	COG0454@1|root,COG0456@2|Bacteria,2IM9R@201174|Actinobacteria,4D0Q0@85004|Bifidobacteriales	201174|Actinobacteria	K	FR47-like protein	rimI	GO:0003674,GO:0003824,GO:0004596,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
IOLKFBCL_01842	326426.Bbr_1123	7.64e-249	683.0	COG0533@1|root,COG0533@2|Bacteria,2GJ98@201174|Actinobacteria,4CZ0K@85004|Bifidobacteriales	201174|Actinobacteria	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
IOLKFBCL_01845	1437608.BBIA_0804	2.35e-95	293.0	2AQRU@1|root,31FZM@2|Bacteria,2IABZ@201174|Actinobacteria,4D0HM@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01846	1437609.BCAL_0562	1.01e-199	556.0	2BM4R@1|root,32FN7@2|Bacteria,2HZNA@201174|Actinobacteria,4D0ZT@85004|Bifidobacteriales	201174|Actinobacteria	S	Putative amidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_6
IOLKFBCL_01847	1437610.BREU_2146	4.88e-181	512.0	COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria,4D0DN@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase and inactivated derivatives IS30 family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
IOLKFBCL_01848	78346.BRUM_1693	4.98e-213	598.0	COG3547@1|root,COG3547@2|Bacteria,2GS79@201174|Actinobacteria,4D0H8@85004|Bifidobacteriales	201174|Actinobacteria	K	Transposase IS116 IS110 IS902	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,HTH_3,HTH_31,Transposase_20
IOLKFBCL_01849	762211.BSTEL_0161	4.9e-27	104.0	COG5658@1|root,COG5658@2|Bacteria,2GWJG@201174|Actinobacteria,4D1RC@85004|Bifidobacteriales	201174|Actinobacteria	S	SdpI/YhfL protein family	-	-	-	-	-	-	-	-	-	-	-	-	SdpI
IOLKFBCL_01852	1122994.AUFR01000044_gene440	1.29e-45	167.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF512,Fer4_12,Fer4_14,Radical_SAM,SPASM
IOLKFBCL_01855	435830.HMPREF0045_01142	2e-120	367.0	COG1132@1|root,COG1132@2|Bacteria,2GJYK@201174|Actinobacteria,4D7BF@85005|Actinomycetales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_tran
IOLKFBCL_01856	1437609.BCAL_0563	2.11e-80	253.0	COG3505@1|root,COG3505@2|Bacteria,2HZ9D@201174|Actinobacteria,4CZ1V@85004|Bifidobacteriales	201174|Actinobacteria	U	Type IV secretory system Conjugative DNA transfer	-	-	-	ko:K03205	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	T4SS-DNA_transf,TraG-D_C
IOLKFBCL_01857	641146.HMPREF9020_01339	1.4e-26	104.0	COG0582@1|root,COG4974@1|root,COG0582@2|Bacteria,COG4974@2|Bacteria,2IH6A@201174|Actinobacteria,4CZ62@85004|Bifidobacteriales	201174|Actinobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
IOLKFBCL_01861	216816.GS08_05830	1.86e-72	223.0	COG3177@1|root,COG3177@2|Bacteria,2GW8P@201174|Actinobacteria,4D1U2@85004|Bifidobacteriales	201174|Actinobacteria	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
IOLKFBCL_01863	1437608.BBIA_2328	8.36e-14	68.9	28UG4@1|root,2ZGM1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01864	1437610.BREU_3931	1.7e-46	154.0	2B5NY@1|root,31YIC@2|Bacteria,2H8QI@201174|Actinobacteria,4D2F4@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01865	1437610.BREU_2146	3.52e-221	615.0	COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria,4D0DN@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase and inactivated derivatives IS30 family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
IOLKFBCL_01866	1688.BCUN_0730	3.1e-57	192.0	COG0323@1|root,COG0323@2|Bacteria,2GPWU@201174|Actinobacteria,4CZXB@85004|Bifidobacteriales	201174|Actinobacteria	L	PFAM Relaxase mobilization nuclease family protein	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
IOLKFBCL_01867	216816.GS08_05820	1.55e-252	694.0	COG1131@1|root,COG1131@2|Bacteria,2GN8P@201174|Actinobacteria,4CZMS@85004|Bifidobacteriales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K20459	ko02010,map02010	M00813	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.124.3,3.A.1.124.4,3.A.1.124.5	-	-	ABC_tran
IOLKFBCL_01868	216816.GS08_05815	2.53e-181	506.0	2EIFD@1|root,33C6R@2|Bacteria,2ICFX@201174|Actinobacteria,4D0JQ@85004|Bifidobacteriales	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K20460	ko02010,map02010	M00813	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.124.3,3.A.1.124.4,3.A.1.124.5	-	-	ABC2_membrane_4
IOLKFBCL_01869	216816.GS08_05810	6.95e-183	511.0	2EDR0@1|root,337KK@2|Bacteria,2GM9U@201174|Actinobacteria,4D0B2@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	ko:K20461	ko02010,map02010	M00813	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.124.3,3.A.1.124.4,3.A.1.124.5	-	-	ABC2_membrane_4
IOLKFBCL_01870	216816.GS08_05805	3.84e-91	269.0	28PS7@1|root,33EAY@2|Bacteria,2H508@201174|Actinobacteria,4D281@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01872	216816.GS08_05795	4.55e-303	827.0	COG4585@1|root,COG4585@2|Bacteria,2GVYN@201174|Actinobacteria,4D0I7@85004|Bifidobacteriales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,HisKA_3
IOLKFBCL_01873	216816.GS08_05790	5.21e-155	436.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4D0EU@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
IOLKFBCL_01875	216816.GS08_05775	1.44e-137	392.0	COG0739@1|root,COG0739@2|Bacteria,2IQ64@201174|Actinobacteria,4D199@85004|Bifidobacteriales	201174|Actinobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
IOLKFBCL_01876	216816.GS08_05770	0.0	918.0	COG4213@1|root,COG4213@2|Bacteria,2HZAK@201174|Actinobacteria,4CZCR@85004|Bifidobacteriales	201174|Actinobacteria	G	ABC transporter substrate-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
IOLKFBCL_01877	216816.GS08_05765	1.11e-305	832.0	COG0538@1|root,COG0538@2|Bacteria,2GM3D@201174|Actinobacteria,4CZ8V@85004|Bifidobacteriales	201174|Actinobacteria	C	Belongs to the isocitrate and isopropylmalate dehydrogenases family	icd	GO:0000287,GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006102,GO:0008150,GO:0008152,GO:0008270,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044464,GO:0045333,GO:0046487,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:0072350	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
IOLKFBCL_01878	216816.GS08_05760	1.07e-264	725.0	COG0516@1|root,COG0516@2|Bacteria,2GKVS@201174|Actinobacteria,4CZDK@85004|Bifidobacteriales	201174|Actinobacteria	F	IMP dehydrogenase family protein	guaB3	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	IMPDH
IOLKFBCL_01879	326426.Bbr_1108	1.98e-91	270.0	2BGJW@1|root,32AI7@2|Bacteria,2IR97@201174|Actinobacteria,4D19G@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01880	216816.GS08_05750	0.0	1281.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4CYVD@85004|Bifidobacteriales	201174|Actinobacteria	I	long-chain-fatty acid CoA ligase	fadD3	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
IOLKFBCL_01881	216816.GS08_05745	4.26e-113	324.0	COG0242@1|root,COG0242@2|Bacteria,2GJ87@201174|Actinobacteria,4CZ63@85004|Bifidobacteriales	201174|Actinobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
IOLKFBCL_01882	216816.GS08_05740	1.37e-186	520.0	COG0052@1|root,COG0052@2|Bacteria,2GMYC@201174|Actinobacteria,4CZ96@85004|Bifidobacteriales	201174|Actinobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
IOLKFBCL_01883	216816.GS08_05735	2.17e-184	514.0	COG0264@1|root,COG0264@2|Bacteria,2GK4M@201174|Actinobacteria,4CYVQ@85004|Bifidobacteriales	201174|Actinobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
IOLKFBCL_01884	326426.Bbr_1103	4.09e-166	465.0	COG0528@1|root,COG0528@2|Bacteria,2GKWQ@201174|Actinobacteria,4CZEK@85004|Bifidobacteriales	201174|Actinobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
IOLKFBCL_01885	216816.GS08_05725	1.86e-115	332.0	COG0233@1|root,COG0233@2|Bacteria,2GJ9J@201174|Actinobacteria,4CYTF@85004|Bifidobacteriales	201174|Actinobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
IOLKFBCL_01886	216816.GS08_05720	1.03e-216	600.0	COG0575@1|root,COG0575@2|Bacteria,2I7ZA@201174|Actinobacteria,4CYZM@85004|Bifidobacteriales	201174|Actinobacteria	I	Cytidylyltransferase family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
IOLKFBCL_01887	216816.GS08_05715	7.52e-284	775.0	COG0820@1|root,COG0820@2|Bacteria,2GJ48@201174|Actinobacteria,4CZG2@85004|Bifidobacteriales	201174|Actinobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
IOLKFBCL_01888	216816.GS08_05710	3.87e-96	281.0	COG0693@1|root,COG0693@2|Bacteria,2GMMW@201174|Actinobacteria,4D0H3@85004|Bifidobacteriales	201174|Actinobacteria	S	DJ-1/PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
IOLKFBCL_01889	216816.GS08_05705	5.87e-180	501.0	COG0107@1|root,COG0107@2|Bacteria,2GIRP@201174|Actinobacteria,4CZ8Z@85004|Bifidobacteriales	201174|Actinobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0008150,GO:0016740,GO:0016757,GO:0016763,GO:0040007	4.1.3.27	ko:K01657,ko:K02500	ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023,M00026	R00985,R00986,R04558	RC00010,RC01190,RC01943,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
IOLKFBCL_01890	216816.GS08_05700	2.31e-91	268.0	COG0139@1|root,COG0139@2|Bacteria,2IKKU@201174|Actinobacteria,4D0WW@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	GO:0008150,GO:0040007	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1606	PRA-CH
IOLKFBCL_01891	216816.GS08_05695	0.0	1013.0	COG0147@1|root,COG0147@2|Bacteria,2GKJT@201174|Actinobacteria,4CZHW@85004|Bifidobacteriales	201174|Actinobacteria	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
IOLKFBCL_01892	216816.GS08_05690	8.02e-144	406.0	COG2039@1|root,COG2039@2|Bacteria,2GN39@201174|Actinobacteria,4D03R@85004|Bifidobacteriales	201174|Actinobacteria	O	Removes 5-oxoproline from various penultimate amino acid residues except L-proline	pcp	GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564	3.4.19.3	ko:K01304	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C15
IOLKFBCL_01893	216816.GS08_05685	2.6e-209	580.0	COG3817@1|root,COG3817@2|Bacteria,2I9GU@201174|Actinobacteria,4D0KP@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF979)	-	-	-	-	-	-	-	-	-	-	-	-	DUF979
IOLKFBCL_01894	216816.GS08_05680	7.79e-153	431.0	COG3819@1|root,COG3819@2|Bacteria,2GP03@201174|Actinobacteria,4CZMP@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF969)	-	-	-	-	-	-	-	-	-	-	-	-	DUF969
IOLKFBCL_01895	216816.GS08_05675	0.0	1034.0	COG0488@1|root,COG0488@2|Bacteria,2GKQ4@201174|Actinobacteria,4CYS2@85004|Bifidobacteriales	201174|Actinobacteria	S	ABC transporter	ybiT	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn,DLIC
IOLKFBCL_01896	216816.GS08_05670	1.44e-165	463.0	COG4221@1|root,COG4221@2|Bacteria,2GMGQ@201174|Actinobacteria,4CZA7@85004|Bifidobacteriales	201174|Actinobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
IOLKFBCL_01897	216816.GS08_05665	1.47e-207	573.0	COG2852@1|root,COG2852@2|Bacteria,2IGTN@201174|Actinobacteria,4D0W9@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
IOLKFBCL_01898	216816.GS08_05660	6.76e-84	247.0	COG3824@1|root,COG3824@2|Bacteria,2IKXW@201174|Actinobacteria,4D10G@85004|Bifidobacteriales	201174|Actinobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
IOLKFBCL_01899	1437610.BREU_0058	1.49e-41	159.0	COG1129@1|root,COG1129@2|Bacteria,2I2G1@201174|Actinobacteria,4CZ58@85004|Bifidobacteriales	201174|Actinobacteria	G	ATPases associated with a variety of cellular activities	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
IOLKFBCL_01900	1437610.BREU_0056	1.22e-17	80.9	2BY0N@1|root,321KG@2|Bacteria,2IEYW@201174|Actinobacteria,4CZZD@85004|Bifidobacteriales	201174|Actinobacteria	S	Hypothetical bacterial integral membrane protein (Trep_Strep)	-	-	-	ko:K16926	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.31	-	-	Trep_Strep
IOLKFBCL_01901	1437609.BCAL_1840	4.88e-152	450.0	COG0642@1|root,COG0642@2|Bacteria,2I436@201174|Actinobacteria,4D01R@85004|Bifidobacteriales	201174|Actinobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K18351	ko01502,ko02020,map01502,map02020	M00651,M00658	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HAMP,HATPase_c,HisKA
IOLKFBCL_01902	216816.GS08_05640	2.48e-149	421.0	COG0745@1|root,COG0745@2|Bacteria,2GKYV@201174|Actinobacteria,4D0I8@85004|Bifidobacteriales	201174|Actinobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
IOLKFBCL_01903	216816.GS08_05635	2.39e-187	521.0	2C1Z0@1|root,2ZDUM@2|Bacteria,2IFSE@201174|Actinobacteria,4D0QC@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01904	1437608.BBIA_0748	1.15e-187	530.0	COG3409@1|root,COG3409@2|Bacteria,2I9HW@201174|Actinobacteria,4D007@85004|Bifidobacteriales	201174|Actinobacteria	M	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1
IOLKFBCL_01905	216816.GS08_05625	2.58e-177	494.0	COG1136@1|root,COG1136@2|Bacteria,2GK3I@201174|Actinobacteria,4D0EN@85004|Bifidobacteriales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IOLKFBCL_01906	1437608.BBIA_0746	2.08e-207	583.0	COG0577@1|root,COG0577@2|Bacteria,2GIRW@201174|Actinobacteria,4D000@85004|Bifidobacteriales	201174|Actinobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
IOLKFBCL_01907	216816.GS08_05615	0.0	1024.0	2ETEZ@1|root,33KYW@2|Bacteria,2HXGA@201174|Actinobacteria,4CZSC@85004|Bifidobacteriales	201174|Actinobacteria	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF3375
IOLKFBCL_01908	216816.GS08_05610	5.2e-147	415.0	2APK1@1|root,31EP8@2|Bacteria,2IEAB@201174|Actinobacteria,4D0C3@85004|Bifidobacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4194)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4194
IOLKFBCL_01909	216816.GS08_05605	0.0	2295.0	COG4913@1|root,COG4913@2|Bacteria,2GMIP@201174|Actinobacteria,4CYWR@85004|Bifidobacteriales	201174|Actinobacteria	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA_29,SbcCD_C
IOLKFBCL_01910	1437608.BBIA_0742	2.87e-16	80.1	COG4924@1|root,COG4924@2|Bacteria,2IB33@201174|Actinobacteria,4D02A@85004|Bifidobacteriales	201174|Actinobacteria	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF2220,DUF3322
IOLKFBCL_01911	216816.GS08_05595	0.0	2003.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,4CYRU@85004|Bifidobacteriales	201174|Actinobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	GO:0000018,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0071944,GO:0080090	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
IOLKFBCL_01912	216816.GS08_05590	0.0	1516.0	COG0322@1|root,COG0322@2|Bacteria,2GIS4@201174|Actinobacteria,4CYVX@85004|Bifidobacteriales	201174|Actinobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0040007,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
IOLKFBCL_01913	216816.GS08_05585	2.62e-237	652.0	COG0169@1|root,COG0169@2|Bacteria,2GPQQ@201174|Actinobacteria,4CZCM@85004|Bifidobacteriales	201174|Actinobacteria	E	Shikimate dehydrogenase substrate binding domain	aroE	GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2552c	Shikimate_DH,Shikimate_dh_N
IOLKFBCL_01914	216816.GS08_05580	1.29e-235	648.0	COG1660@1|root,COG1660@2|Bacteria,2GMWB@201174|Actinobacteria,4CZ70@85004|Bifidobacteriales	201174|Actinobacteria	S	Displays ATPase and GTPase activities	yvcJ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
IOLKFBCL_01915	216816.GS08_05575	1.42e-217	601.0	COG1481@1|root,COG1481@2|Bacteria,2GJZU@201174|Actinobacteria,4CYTD@85004|Bifidobacteriales	201174|Actinobacteria	K	May be required for sporulation	whiA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0043937,GO:0044464,GO:0050789,GO:0050793,GO:0065007,GO:0071944	-	ko:K09762	-	-	-	-	ko00000	-	-	-	HTH_WhiA,LAGLIDADG_WhiA,WhiA_N
IOLKFBCL_01916	216816.GS08_05570	1.84e-281	770.0	COG0126@1|root,COG0126@2|Bacteria,2GJC6@201174|Actinobacteria,4CZJ3@85004|Bifidobacteriales	201174|Actinobacteria	F	Phosphoglycerate kinase	pgk	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044464,GO:0071944	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
IOLKFBCL_01917	216816.GS08_05565	7.71e-186	517.0	COG0149@1|root,COG0149@2|Bacteria,2GJXZ@201174|Actinobacteria,4CYSG@85004|Bifidobacteriales	201174|Actinobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
IOLKFBCL_01918	326426.Bbr_0996	2.51e-47	152.0	COG1314@1|root,COG1314@2|Bacteria,2GR31@201174|Actinobacteria,4D16U@85004|Bifidobacteriales	201174|Actinobacteria	U	Preprotein translocase SecG subunit	secG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
IOLKFBCL_01919	216816.GS08_05555	3.95e-224	618.0	COG0039@1|root,COG0039@2|Bacteria,2IASS@201174|Actinobacteria,4CZRT@85004|Bifidobacteriales	201174|Actinobacteria	C	Belongs to the LDH MDH superfamily	ldh	-	1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	-	R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
IOLKFBCL_01920	216816.GS08_05550	2.17e-209	578.0	COG0561@1|root,COG0561@2|Bacteria,2HZYB@201174|Actinobacteria,4CZQW@85004|Bifidobacteriales	201174|Actinobacteria	S	Sucrose-6F-phosphate phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
IOLKFBCL_01921	1437610.BREU_0030	7.96e-317	870.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,4CZVJ@85004|Bifidobacteriales	201174|Actinobacteria	E	Aminotransferase, class I II	aspC	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.6.1.1,2.6.1.2,2.6.1.66	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	iNJ661.Rv0337c	Aminotran_1_2
IOLKFBCL_01922	216816.GS08_05540	2.16e-276	761.0	COG0534@1|root,COG0534@2|Bacteria,2GXXK@201174|Actinobacteria,4D04E@85004|Bifidobacteriales	201174|Actinobacteria	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
IOLKFBCL_01923	326426.Bbr_1001	2.15e-272	751.0	COG1114@1|root,COG1114@2|Bacteria,2GNMD@201174|Actinobacteria,4CZIP@85004|Bifidobacteriales	201174|Actinobacteria	U	Component of the transport system for branched-chain amino acids	brnQ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03311	-	-	-	-	ko00000	2.A.26	-	-	Branch_AA_trans
IOLKFBCL_01924	216816.GS08_05525	3.03e-256	703.0	COG0176@1|root,COG0176@2|Bacteria,2GMF9@201174|Actinobacteria,4CZ3J@85004|Bifidobacteriales	201174|Actinobacteria	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
IOLKFBCL_01925	216816.GS08_05520	0.0	1395.0	COG0021@1|root,COG0021@2|Bacteria,2GJ1K@201174|Actinobacteria,4CZ64@85004|Bifidobacteriales	201174|Actinobacteria	H	Belongs to the transketolase family	tkt	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
IOLKFBCL_01926	216816.GS08_05515	4.28e-238	658.0	COG1420@1|root,COG1420@2|Bacteria,2GKF5@201174|Actinobacteria,4CZK3@85004|Bifidobacteriales	201174|Actinobacteria	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HTH_DeoR,HrcA
IOLKFBCL_01927	216816.GS08_05510	3.8e-273	747.0	COG0484@1|root,COG0484@2|Bacteria,2GK69@201174|Actinobacteria,4D03K@85004|Bifidobacteriales	201174|Actinobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
IOLKFBCL_01928	216816.GS08_05505	1.07e-199	551.0	COG3001@1|root,COG3001@2|Bacteria,2GW7W@201174|Actinobacteria,4CZ4W@85004|Bifidobacteriales	201174|Actinobacteria	G	Fructosamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
IOLKFBCL_01929	216816.GS08_05500	1.14e-196	546.0	COG1968@1|root,COG1968@2|Bacteria,2GJVG@201174|Actinobacteria,4CZ83@85004|Bifidobacteriales	201174|Actinobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
IOLKFBCL_01930	216816.GS08_05495	8.61e-206	568.0	COG1938@1|root,COG1938@2|Bacteria,2GK10@201174|Actinobacteria,4CYSJ@85004|Bifidobacteriales	201174|Actinobacteria	S	PAC2 family	-	-	-	-	-	-	-	-	-	-	-	-	PAC2
IOLKFBCL_01936	326426.Bbr_1009	0.0	1352.0	COG0441@1|root,COG0441@2|Bacteria,2GKTC@201174|Actinobacteria,4CZD3@85004|Bifidobacteriales	201174|Actinobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
IOLKFBCL_01937	326426.Bbr_1010	5.37e-143	402.0	COG0537@1|root,COG0537@2|Bacteria,2GJT5@201174|Actinobacteria,4CZS7@85004|Bifidobacteriales	201174|Actinobacteria	FG	HIT domain	-	GO:0003674,GO:0003824,GO:0003877,GO:0004551,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008796,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009987,GO:0015959,GO:0015961,GO:0015965,GO:0015967,GO:0016020,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070566,GO:0071704,GO:0071944,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
IOLKFBCL_01938	326426.Bbr_1011	3.41e-156	441.0	COG0217@1|root,COG0217@2|Bacteria,2GJ4G@201174|Actinobacteria,4CZ9X@85004|Bifidobacteriales	201174|Actinobacteria	K	transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
IOLKFBCL_01939	326426.Bbr_1012	1.58e-126	361.0	COG0817@1|root,COG0817@2|Bacteria,2GJI5@201174|Actinobacteria,4CZ79@85004|Bifidobacteriales	201174|Actinobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
IOLKFBCL_01940	216816.GS08_05445	4.97e-114	330.0	COG0632@1|root,COG0632@2|Bacteria,2GN17@201174|Actinobacteria,4CZCE@85004|Bifidobacteriales	201174|Actinobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009378,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
IOLKFBCL_01941	216816.GS08_05440	3.32e-242	667.0	COG2255@1|root,COG2255@2|Bacteria,2GJZF@201174|Actinobacteria,4CZGU@85004|Bifidobacteriales	201174|Actinobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
IOLKFBCL_01942	216816.GS08_05435	4.71e-51	166.0	COG1862@1|root,COG1862@2|Bacteria,2IKUJ@201174|Actinobacteria,4D139@85004|Bifidobacteriales	201174|Actinobacteria	U	Preprotein translocase subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
IOLKFBCL_01943	216816.GS08_05430	3.96e-115	332.0	COG0503@1|root,COG0503@2|Bacteria,2IM7C@201174|Actinobacteria,4CZ9H@85004|Bifidobacteriales	201174|Actinobacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
IOLKFBCL_01944	216816.GS08_05425	4.58e-270	741.0	COG0045@1|root,COG0045@2|Bacteria,2GKSB@201174|Actinobacteria,4CZCQ@85004|Bifidobacteriales	201174|Actinobacteria	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
IOLKFBCL_01945	216816.GS08_05420	2.48e-200	556.0	COG0074@1|root,COG0074@2|Bacteria,2GK00@201174|Actinobacteria,4CYX1@85004|Bifidobacteriales	201174|Actinobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
IOLKFBCL_01946	216816.GS08_05415	1.97e-310	848.0	2EKVE@1|root,33EIZ@2|Bacteria,2HZ8H@201174|Actinobacteria,4CYRN@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01947	216816.GS08_05410	0.0	1060.0	COG0138@1|root,COG0138@2|Bacteria,2GJWU@201174|Actinobacteria,4CZ3P@85004|Bifidobacteriales	201174|Actinobacteria	F	Bifunctional purine biosynthesis protein PurH	purH	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
IOLKFBCL_01948	762211.BSTEL_0211	1.69e-41	138.0	2AXAE@1|root,31P9H@2|Bacteria,2IQKC@201174|Actinobacteria,4D18B@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3017
IOLKFBCL_01949	216816.GS08_05405	6.05e-206	572.0	COG0580@1|root,COG0580@2|Bacteria,2HZ9W@201174|Actinobacteria,4CZ5Q@85004|Bifidobacteriales	201174|Actinobacteria	U	Belongs to the MIP aquaporin (TC 1.A.8) family	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
IOLKFBCL_01950	216816.GS08_05400	1.29e-183	510.0	COG1187@1|root,COG1187@2|Bacteria,2GJ4N@201174|Actinobacteria,4CZGG@85004|Bifidobacteriales	201174|Actinobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluB	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
IOLKFBCL_01951	216816.GS08_05395	0.0	1361.0	COG0283@1|root,COG1160@1|root,COG0283@2|Bacteria,COG1160@2|Bacteria,2GJ8J@201174|Actinobacteria,4CYSE@85004|Bifidobacteriales	201174|Actinobacteria	F	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	Cytidylate_kin,KH_dom-like,MMR_HSR1
IOLKFBCL_01953	216816.GS08_05385	0.0	1017.0	COG4284@1|root,COG4284@2|Bacteria,2I2G3@201174|Actinobacteria,4CYTQ@85004|Bifidobacteriales	201174|Actinobacteria	G	UTP-glucose-1-phosphate uridylyltransferase	ugp	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPGP
IOLKFBCL_01954	216816.GS08_05380	0.0	1222.0	COG2378@1|root,COG2378@2|Bacteria,2I8M5@201174|Actinobacteria,4CZWF@85004|Bifidobacteriales	201174|Actinobacteria	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	WYL
IOLKFBCL_01955	216816.GS08_05375	7.59e-64	195.0	2B5BE@1|root,31Y5K@2|Bacteria,2IQT5@201174|Actinobacteria,4D17A@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01956	216816.GS08_05370	0.0	1675.0	COG4581@1|root,COG4581@2|Bacteria,2GJEX@201174|Actinobacteria,4CZEC@85004|Bifidobacteriales	201174|Actinobacteria	L	DEAD DEAH box helicase	helY	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575	-	ko:K03727	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DSHCT,Helicase_C,rRNA_proc-arch
IOLKFBCL_01957	216816.GS08_05365	6.43e-81	239.0	2CNY9@1|root,32SI2@2|Bacteria,2IMK6@201174|Actinobacteria,4D0V5@85004|Bifidobacteriales	201174|Actinobacteria	K	Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters	rbpA	GO:0001000,GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0043167,GO:0043169,GO:0043175,GO:0045893,GO:0045935,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070063,GO:0080090,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	RbpA
IOLKFBCL_01958	326426.Bbr_1030	1.96e-165	463.0	COG0546@1|root,COG0546@2|Bacteria,2HFGX@201174|Actinobacteria,4CYSF@85004|Bifidobacteriales	201174|Actinobacteria	S	HAD-hyrolase-like	nt5e	GO:0003674,GO:0003824,GO:0004672,GO:0004713,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018108,GO:0018193,GO:0018212,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0071704,GO:0140096,GO:1901564	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
IOLKFBCL_01959	326426.Bbr_1031	3.46e-50	158.0	2BB9R@1|root,324SH@2|Bacteria,2H9QN@201174|Actinobacteria,4D2DN@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01960	398513.BBNG_00607	8.45e-96	300.0	COG0582@1|root,COG0582@2|Bacteria,2GMMI@201174|Actinobacteria,4D0E4@85004|Bifidobacteriales	201174|Actinobacteria	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase
IOLKFBCL_01962	1034101.G1D1G4_9CAUD	3.63e-99	307.0	4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses  no RNA stage,4QPQ9@28883|Caudovirales	28883|Caudovirales	S	N-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01963	1123013.AUIC01000006_gene1317	4.85e-42	158.0	COG0675@1|root,COG0675@2|Bacteria,2GM6K@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
IOLKFBCL_01966	1366050.N234_34740	2.65e-30	129.0	COG3550@1|root,COG3550@2|Bacteria,1MVAB@1224|Proteobacteria,2VK2U@28216|Betaproteobacteria,1K0T9@119060|Burkholderiaceae	28216|Betaproteobacteria	S	HipA N-terminal domain protein	hipA	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
IOLKFBCL_01968	702459.BBPR_0778	2.05e-164	470.0	COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria,4D0DN@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase and inactivated derivatives IS30 family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
IOLKFBCL_01970	203267.TWT_175	2.34e-56	185.0	COG1136@1|root,COG1136@2|Bacteria,2GNB3@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	hrtA	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IOLKFBCL_01972	216816.GS08_05350	2.66e-74	225.0	29TZI@1|root,30F8H@2|Bacteria,2ISJH@201174|Actinobacteria,4D0Z6@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01973	216816.GS08_05345	6.65e-145	409.0	COG0789@1|root,COG0789@2|Bacteria,2GM67@201174|Actinobacteria,4CZ0X@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	merR2	-	-	-	-	-	-	-	-	-	-	-	MerR_1
IOLKFBCL_01974	216816.GS08_05340	1.17e-96	281.0	COG1716@1|root,COG1716@2|Bacteria,2GK99@201174|Actinobacteria,4D0R3@85004|Bifidobacteriales	201174|Actinobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	garA	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006110,GO:0006140,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010563,GO:0010675,GO:0010677,GO:0016020,GO:0016310,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0030312,GO:0030808,GO:0030809,GO:0030811,GO:0030812,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031330,GO:0036211,GO:0042325,GO:0042326,GO:0042802,GO:0043170,GO:0043412,GO:0043457,GO:0043467,GO:0043470,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045820,GO:0045912,GO:0045934,GO:0045936,GO:0045980,GO:0046777,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051174,GO:0051193,GO:0051195,GO:0051196,GO:0051198,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1900371,GO:1900372,GO:1900542,GO:1900543,GO:1901564,GO:1903578,GO:1903579,GO:2001169,GO:2001170	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl,zinc_ribbon_2
IOLKFBCL_01975	216816.GS08_05335	1.03e-177	497.0	COG3879@1|root,COG3879@2|Bacteria,2GJ3C@201174|Actinobacteria,4CYYH@85004|Bifidobacteriales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF881)	-	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF881
IOLKFBCL_01976	216816.GS08_05330	7.03e-51	163.0	COG3856@1|root,COG3856@2|Bacteria,2IKJW@201174|Actinobacteria,4D12G@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF1290)	sbp	-	-	-	-	-	-	-	-	-	-	-	DUF1290
IOLKFBCL_01977	216816.GS08_05325	1.5e-196	549.0	COG3879@1|root,COG3879@2|Bacteria,2GMS5@201174|Actinobacteria,4CZ72@85004|Bifidobacteriales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF881)	-	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF881
IOLKFBCL_01978	216816.GS08_05320	7.77e-137	388.0	COG0558@1|root,COG0558@2|Bacteria,2GM3F@201174|Actinobacteria,4CZGD@85004|Bifidobacteriales	201174|Actinobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA2	GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
IOLKFBCL_01979	216816.GS08_05315	1.84e-201	558.0	COG0040@1|root,COG0040@2|Bacteria,2GNAX@201174|Actinobacteria,4CZ66@85004|Bifidobacteriales	201174|Actinobacteria	F	ATP phosphoribosyltransferase	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
IOLKFBCL_01980	216816.GS08_05310	3.56e-56	174.0	COG0140@1|root,COG0140@2|Bacteria,2IQ4D@201174|Actinobacteria,4D108@85004|Bifidobacteriales	201174|Actinobacteria	E	Phosphoribosyl-ATP pyrophosphohydrolase	hisE	GO:0000287,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0009605,GO:0009607,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0043207,GO:0044403,GO:0044419,GO:0044464,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0071944,GO:0075136,GO:0075139	3.6.1.31	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-PH
IOLKFBCL_01981	216816.GS08_05305	4.64e-151	425.0	COG0036@1|root,COG0036@2|Bacteria,2GJZ9@201174|Actinobacteria,4CYX0@85004|Bifidobacteriales	201174|Actinobacteria	G	Ribulose-phosphate 3-epimerase	rpe	GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
IOLKFBCL_01982	216816.GS08_05300	4.02e-237	650.0	COG0682@1|root,COG0682@2|Bacteria,2GKSS@201174|Actinobacteria,4CYV8@85004|Bifidobacteriales	201174|Actinobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	LGT
IOLKFBCL_01983	326426.Bbr_1043	7.76e-202	559.0	COG0159@1|root,COG0159@2|Bacteria,2GN6T@201174|Actinobacteria,4D0A3@85004|Bifidobacteriales	201174|Actinobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
IOLKFBCL_01984	216816.GS08_05290	0.0	1352.0	COG0133@1|root,COG0134@1|root,COG0133@2|Bacteria,COG0134@2|Bacteria,2GM7Z@201174|Actinobacteria,4CZJW@85004|Bifidobacteriales	201174|Actinobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	GO:0000162,GO:0003674,GO:0003824,GO:0004834,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS,PALP
IOLKFBCL_01985	326426.Bbr_1045	1.84e-170	475.0	COG2135@1|root,COG2135@2|Bacteria,2GKY8@201174|Actinobacteria,4CZPW@85004|Bifidobacteriales	201174|Actinobacteria	S	SOS response associated peptidase (SRAP)	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
IOLKFBCL_01986	216816.GS08_05280	1.51e-198	550.0	COG0648@1|root,COG0648@2|Bacteria,2GJJQ@201174|Actinobacteria,4CZ0H@85004|Bifidobacteriales	201174|Actinobacteria	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
IOLKFBCL_01987	216816.GS08_05275	0.0	884.0	COG0833@1|root,COG0833@2|Bacteria,2I2DX@201174|Actinobacteria,4D2V7@85004|Bifidobacteriales	201174|Actinobacteria	E	amino acid	-	-	-	ko:K16235	-	-	-	-	ko00000,ko02000	2.A.3.1.10	-	-	AA_permease
IOLKFBCL_01988	216816.GS08_05270	3.21e-111	321.0	COG0477@1|root,COG2814@2|Bacteria,2I8QF@201174|Actinobacteria,4CZF1@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
IOLKFBCL_01989	326426.Bbr_1049	1.47e-241	664.0	COG4767@1|root,COG4767@2|Bacteria,2H595@201174|Actinobacteria,4CZBZ@85004|Bifidobacteriales	201174|Actinobacteria	V	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	RDD,VanZ
IOLKFBCL_01990	749414.SBI_00921	4.21e-63	208.0	COG0520@1|root,COG0520@2|Bacteria,2GNM2@201174|Actinobacteria	201174|Actinobacteria	E	Aminotransferase, class V	cefD	-	5.1.1.17	ko:K04127	ko00311,ko01100,ko01130,map00311,map01100,map01130	M00673	R04147	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
IOLKFBCL_01991	216816.GS08_05240	7.82e-118	337.0	COG0454@1|root,COG0456@2|Bacteria,2HZQT@201174|Actinobacteria,4D1A5@85004|Bifidobacteriales	201174|Actinobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
IOLKFBCL_01992	326426.Bbr_1054	2.03e-33	116.0	COG4367@1|root,COG4367@2|Bacteria,2IPTA@201174|Actinobacteria,4D10S@85004|Bifidobacteriales	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2316)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2316
IOLKFBCL_01993	216816.GS08_05230	6.4e-129	365.0	COG3981@1|root,COG3981@2|Bacteria,2HEQC@201174|Actinobacteria,4D0EK@85004|Bifidobacteriales	201174|Actinobacteria	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
IOLKFBCL_01994	158787.BSCA_0159	3.82e-36	128.0	COG3293@1|root,COG3293@2|Bacteria,2GX1N@201174|Actinobacteria,4D2D5@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_2
IOLKFBCL_01995	762211.BSTEL_1667	0.0	1107.0	COG0591@1|root,COG0591@2|Bacteria,2GKPW@201174|Actinobacteria,4D21N@85004|Bifidobacteriales	201174|Actinobacteria	E	Sodium:solute symporter family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
IOLKFBCL_01996	762211.BSTEL_1668	9.29e-57	178.0	2C74X@1|root,305RB@2|Bacteria,2HZZ3@201174|Actinobacteria,4D2BV@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_01997	1147128.BAST_1028	4.94e-109	334.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	-	-	-	ko:K02445,ko:K03762	-	-	-	-	ko00000,ko02000	2.A.1.4.3,2.A.1.6.4	-	-	MFS_1
IOLKFBCL_01998	269797.Mbar_A3206	2.1e-09	67.0	COG0585@1|root,arCOG04252@2157|Archaea,2XUTK@28890|Euryarchaeota,2N928@224756|Methanomicrobia	224756|Methanomicrobia	J	Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs	truD	-	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
IOLKFBCL_01999	158787.BSCA_0159	3.1e-59	185.0	COG3293@1|root,COG3293@2|Bacteria,2GX1N@201174|Actinobacteria,4D2D5@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_2
IOLKFBCL_02000	216816.GS08_05225	3.52e-61	189.0	2B0WB@1|root,31T91@2|Bacteria,2GRYR@201174|Actinobacteria,4D1GV@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_02001	326426.Bbr_1057	1.39e-155	438.0	arCOG08992@1|root,333S7@2|Bacteria,2IPD5@201174|Actinobacteria,4CZX8@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Abi_2
IOLKFBCL_02004	158787.BSCA_2269	3.05e-61	203.0	COG4585@1|root,COG4585@2|Bacteria,2GVWR@201174|Actinobacteria,4D03H@85004|Bifidobacteriales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
IOLKFBCL_02005	326426.Bbr_1060	1.82e-258	711.0	COG4585@1|root,COG4585@2|Bacteria,2GVWR@201174|Actinobacteria,4D03H@85004|Bifidobacteriales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
IOLKFBCL_02006	216816.GS08_05195	3.69e-166	464.0	COG2197@1|root,COG2197@2|Bacteria,2IAQ5@201174|Actinobacteria,4D0E3@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
IOLKFBCL_02007	216816.GS08_05190	5.1e-125	355.0	2DCFI@1|root,2ZDXV@2|Bacteria,2GWSG@201174|Actinobacteria,4D1VT@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_02008	216816.GS08_05185	4.14e-200	555.0	COG0845@1|root,COG0845@2|Bacteria,2IFY7@201174|Actinobacteria,4D13B@85004|Bifidobacteriales	201174|Actinobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
IOLKFBCL_02009	326426.Bbr_1064	1.75e-157	442.0	COG4181@1|root,COG4181@2|Bacteria,2I5GS@201174|Actinobacteria,4D2XS@85004|Bifidobacteriales	201174|Actinobacteria	Q	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IOLKFBCL_02010	216816.GS08_05175	3.18e-234	649.0	COG0577@1|root,COG0577@2|Bacteria,2HXTZ@201174|Actinobacteria,4CZYZ@85004|Bifidobacteriales	201174|Actinobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
IOLKFBCL_02011	326426.Bbr_1066	1.49e-53	168.0	COG3077@1|root,COG3077@2|Bacteria,2GV25@201174|Actinobacteria,4D179@85004|Bifidobacteriales	201174|Actinobacteria	L	RelB antitoxin	-	-	-	ko:K07473	-	-	-	-	ko00000,ko02048	-	-	-	RelB
IOLKFBCL_02012	326426.Bbr_1067	2.98e-64	196.0	COG3041@1|root,COG3041@2|Bacteria,2GSX9@201174|Actinobacteria,4D1AZ@85004|Bifidobacteriales	201174|Actinobacteria	S	Bacterial toxin of type II toxin-antitoxin system, YafQ	-	-	-	ko:K19157	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	YafQ_toxin
IOLKFBCL_02013	1687.BCOR_0393	6.23e-35	131.0	COG2211@1|root,COG2211@2|Bacteria,2GJZG@201174|Actinobacteria,4CZ93@85004|Bifidobacteriales	201174|Actinobacteria	G	Transporter major facilitator family protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
IOLKFBCL_02014	326426.Bbr_1090	0.0	989.0	COG0833@1|root,COG0833@2|Bacteria,2I2DX@201174|Actinobacteria,4D2V7@85004|Bifidobacteriales	201174|Actinobacteria	E	amino acid	-	-	-	ko:K16235	-	-	-	-	ko00000,ko02000	2.A.3.1.10	-	-	AA_permease
IOLKFBCL_02016	543734.LCABL_29330	3.35e-116	351.0	COG0477@1|root,COG2814@2|Bacteria,1TQZ7@1239|Firmicutes,4HERG@91061|Bacilli,3F54C@33958|Lactobacillaceae	91061|Bacilli	EGP	Transporter, major facilitator family protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
IOLKFBCL_02017	216816.GS08_02090	2.54e-266	729.0	COG1609@1|root,COG1609@2|Bacteria,2GK1X@201174|Actinobacteria,4CYR6@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
IOLKFBCL_02018	216816.GS08_02085	1.1e-190	530.0	COG0164@1|root,COG0164@2|Bacteria,2GJFN@201174|Actinobacteria,4CZ1U@85004|Bifidobacteriales	201174|Actinobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
IOLKFBCL_02019	216816.GS08_02080	1.23e-188	525.0	COG0681@1|root,COG0681@2|Bacteria,2GIYN@201174|Actinobacteria,4CZEY@85004|Bifidobacteriales	201174|Actinobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
IOLKFBCL_02020	216816.GS08_02075	6.79e-79	234.0	COG0335@1|root,COG0335@2|Bacteria,2IHRT@201174|Actinobacteria,4D0V2@85004|Bifidobacteriales	201174|Actinobacteria	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
IOLKFBCL_02022	216816.GS08_02070	0.0	1139.0	COG4986@1|root,COG4986@2|Bacteria,2GNF7@201174|Actinobacteria,4CZJS@85004|Bifidobacteriales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
IOLKFBCL_02023	216816.GS08_02065	0.0	895.0	COG1116@1|root,COG4754@1|root,COG1116@2|Bacteria,COG4754@2|Bacteria,2GN33@201174|Actinobacteria,4D00C@85004|Bifidobacteriales	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	AAA_assoc_C,ABC_tran
IOLKFBCL_02024	216816.GS08_02060	0.0	1138.0	COG0166@1|root,COG0166@2|Bacteria,2GJG0@201174|Actinobacteria,4CYVV@85004|Bifidobacteriales	201174|Actinobacteria	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
IOLKFBCL_02027	216816.GS08_02045	3.33e-220	609.0	COG0679@1|root,COG0679@2|Bacteria,2GN0R@201174|Actinobacteria,4CZ6C@85004|Bifidobacteriales	201174|Actinobacteria	S	Auxin Efflux Carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
IOLKFBCL_02028	216816.GS08_02040	5.57e-307	837.0	COG2348@1|root,COG2348@2|Bacteria,2HZ91@201174|Actinobacteria,4CYZJ@85004|Bifidobacteriales	201174|Actinobacteria	V	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K12554	ko00550,ko01100,map00550,map01100	-	R08780	RC00055,RC00064	ko00000,ko00001,ko01000,ko01011	-	-	-	FemAB
IOLKFBCL_02029	216816.GS08_02035	3.97e-312	850.0	COG2348@1|root,COG2348@2|Bacteria,2HZ91@201174|Actinobacteria,4CYZJ@85004|Bifidobacteriales	201174|Actinobacteria	V	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K12554	ko00550,ko01100,map00550,map01100	-	R08780	RC00055,RC00064	ko00000,ko00001,ko01000,ko01011	-	-	-	FemAB
IOLKFBCL_02030	216816.GS08_02030	4.58e-288	788.0	COG2348@1|root,COG2348@2|Bacteria,2HZ91@201174|Actinobacteria,4CYZJ@85004|Bifidobacteriales	201174|Actinobacteria	V	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K12554	ko00550,ko01100,map00550,map01100	-	R08780	RC00055,RC00064	ko00000,ko00001,ko01000,ko01011	-	-	-	FemAB
IOLKFBCL_02032	216816.GS08_02020	2.87e-169	474.0	COG0127@1|root,COG0127@2|Bacteria,2GM2B@201174|Actinobacteria,4CZ3F@85004|Bifidobacteriales	201174|Actinobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
IOLKFBCL_02033	216816.GS08_02015	2.22e-185	515.0	COG0689@1|root,COG0689@2|Bacteria,2GJFI@201174|Actinobacteria,4CZBF@85004|Bifidobacteriales	201174|Actinobacteria	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
IOLKFBCL_02034	216816.GS08_02010	5.53e-206	569.0	2B8QT@1|root,3220I@2|Bacteria,2H680@201174|Actinobacteria,4D2CV@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_02035	216816.GS08_02005	1.4e-314	857.0	COG1488@1|root,COG1488@2|Bacteria,2GJAT@201174|Actinobacteria,4CYUR@85004|Bifidobacteriales	201174|Actinobacteria	F	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase
IOLKFBCL_02036	216816.GS08_02000	1.71e-155	435.0	2DSRR@1|root,33H72@2|Bacteria,2I2H5@201174|Actinobacteria,4CZAT@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_02037	326426.Bbr_0399	7.11e-91	266.0	COG0789@1|root,COG0789@2|Bacteria,2HZMI@201174|Actinobacteria,4D0Y1@85004|Bifidobacteriales	201174|Actinobacteria	K	MerR, DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
IOLKFBCL_02038	216816.GS08_01990	4.06e-243	667.0	COG0667@1|root,COG0667@2|Bacteria,2GMT5@201174|Actinobacteria,4CZ25@85004|Bifidobacteriales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
IOLKFBCL_02039	216816.GS08_01985	3.9e-69	208.0	2CAFG@1|root,32ZDZ@2|Bacteria,2I800@201174|Actinobacteria,4D107@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3039)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3039
IOLKFBCL_02040	216816.GS08_01980	2.45e-114	328.0	COG0669@1|root,COG0669@2|Bacteria,2GN1S@201174|Actinobacteria,4CYR5@85004|Bifidobacteriales	201174|Actinobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016043,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0022607,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034214,GO:0034641,GO:0034654,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0055086,GO:0065003,GO:0070566,GO:0071704,GO:0071840,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
IOLKFBCL_02041	216816.GS08_01975	5.73e-175	492.0	2EKTZ@1|root,33EHP@2|Bacteria,2HZD3@201174|Actinobacteria,4CZV9@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_02042	216816.GS08_01970	8.82e-154	431.0	COG1399@1|root,COG1399@2|Bacteria,2GJTS@201174|Actinobacteria,4CZ0J@85004|Bifidobacteriales	201174|Actinobacteria	S	Uncharacterized ACR, COG1399	-	GO:0008150,GO:0040007	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
IOLKFBCL_02043	216816.GS08_01965	3.14e-42	137.0	COG0333@1|root,COG0333@2|Bacteria,2GQP3@201174|Actinobacteria,4D18N@85004|Bifidobacteriales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
IOLKFBCL_02044	216816.GS08_01960	5.2e-167	467.0	COG0571@1|root,COG0571@2|Bacteria,2GKER@201174|Actinobacteria,4CZ98@85004|Bifidobacteriales	201174|Actinobacteria	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
IOLKFBCL_02045	216816.GS08_01955	0.0	1286.0	COG0028@1|root,COG0028@2|Bacteria,2GKU4@201174|Actinobacteria,4CYR0@85004|Bifidobacteriales	201174|Actinobacteria	H	Thiamine pyrophosphate enzyme, central domain	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
IOLKFBCL_02046	216816.GS08_01950	5.15e-118	338.0	COG0440@1|root,COG0440@2|Bacteria,2GJCH@201174|Actinobacteria,4CYXX@85004|Bifidobacteriales	201174|Actinobacteria	E	ACT domain	ilvN	GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0030312,GO:0032991,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
IOLKFBCL_02047	216816.GS08_01945	3.08e-57	177.0	COG4691@1|root,COG4691@2|Bacteria,2GRCV@201174|Actinobacteria,4D1GB@85004|Bifidobacteriales	201174|Actinobacteria	S	Plasmid stability protein	-	-	-	ko:K21495	-	-	-	-	ko00000,ko02048	-	-	-	Arc
IOLKFBCL_02048	1437610.BREU_1819	9.76e-83	246.0	COG1487@1|root,COG1487@2|Bacteria,2IS29@201174|Actinobacteria,4D1D3@85004|Bifidobacteriales	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	-	ko:K07062	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN
IOLKFBCL_02049	216816.GS08_01940	0.0	1453.0	COG0488@1|root,COG0488@2|Bacteria,2GJ5M@201174|Actinobacteria,4CZCU@85004|Bifidobacteriales	201174|Actinobacteria	S	ABC transporter	yjjK	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
IOLKFBCL_02050	216816.GS08_01935	1.07e-174	488.0	COG0518@1|root,COG0518@2|Bacteria,2GNA6@201174|Actinobacteria,4CYR4@85004|Bifidobacteriales	201174|Actinobacteria	F	Peptidase C26	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,Methyltransf_11
IOLKFBCL_02051	216816.GS08_01930	0.0	1062.0	COG0215@1|root,COG0215@2|Bacteria,2GJF2@201174|Actinobacteria,4CZZ9@85004|Bifidobacteriales	201174|Actinobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
IOLKFBCL_02052	216816.GS08_01925	4.51e-207	573.0	COG3965@1|root,COG3965@2|Bacteria,2H4CC@201174|Actinobacteria,4CZ1H@85004|Bifidobacteriales	201174|Actinobacteria	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
IOLKFBCL_02053	326426.Bbr_0383	0.0	998.0	COG0541@1|root,COG0541@2|Bacteria,2GK4R@201174|Actinobacteria,4CYY1@85004|Bifidobacteriales	201174|Actinobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
IOLKFBCL_02054	216816.GS08_01915	8.12e-230	637.0	COG3021@1|root,COG3021@2|Bacteria,2GK2H@201174|Actinobacteria,4CYS3@85004|Bifidobacteriales	201174|Actinobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
IOLKFBCL_02055	216816.GS08_01910	1.76e-104	302.0	COG0054@1|root,COG0054@2|Bacteria,2II1Z@201174|Actinobacteria,4CZPT@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0040007,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
IOLKFBCL_02056	216816.GS08_01905	5.44e-299	814.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,2GIWJ@201174|Actinobacteria,4D0N2@85004|Bifidobacteriales	201174|Actinobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
IOLKFBCL_02057	216816.GS08_01900	2.51e-144	407.0	COG0307@1|root,COG0307@2|Bacteria,2GKC5@201174|Actinobacteria,4D024@85004|Bifidobacteriales	201174|Actinobacteria	H	Lumazine binding domain	ribE	GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
IOLKFBCL_02058	216816.GS08_01895	1.79e-268	734.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,2GKAX@201174|Actinobacteria,4D2XR@85004|Bifidobacteriales	201174|Actinobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
IOLKFBCL_02059	216816.GS08_01890	0.0	934.0	COG0147@1|root,COG0147@2|Bacteria,2GKJT@201174|Actinobacteria,4D20E@85004|Bifidobacteriales	201174|Actinobacteria	EH	chorismate binding enzyme	pabB	-	2.6.1.85,4.1.3.27,4.1.3.38	ko:K01657,ko:K01665,ko:K03342,ko:K13950	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716,R05553	RC00010,RC01418,RC01843,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Anth_synt_I_N,Chorismate_bind,GATase
IOLKFBCL_02060	216816.GS08_01885	1.28e-183	511.0	COG0115@1|root,COG0115@2|Bacteria	2|Bacteria	E	branched-chain-amino-acid transaminase activity	pabC	-	2.6.1.42,2.6.1.85,4.1.3.38	ko:K00826,ko:K01665,ko:K02619,ko:K03342	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R01716,R02199,R05553,R10991	RC00006,RC00010,RC00036,RC01418,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4,Anth_synt_I_N,Chorismate_bind
IOLKFBCL_02061	216816.GS08_01880	1.66e-83	249.0	COG0228@1|root,COG0228@2|Bacteria,2IKU0@201174|Actinobacteria,4D0PE@85004|Bifidobacteriales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
IOLKFBCL_02062	216816.GS08_01875	1.24e-47	152.0	COG1837@1|root,COG1837@2|Bacteria,2IQ4C@201174|Actinobacteria,4D16Z@85004|Bifidobacteriales	201174|Actinobacteria	S	Belongs to the UPF0109 family	-	GO:0008150,GO:0040007	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
IOLKFBCL_02063	216816.GS08_01870	9.5e-142	400.0	COG0806@1|root,COG0806@2|Bacteria,2GK4I@201174|Actinobacteria,4D0C6@85004|Bifidobacteriales	201174|Actinobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	GO:0008150,GO:0040007	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
IOLKFBCL_02064	216816.GS08_01865	3.36e-61	188.0	COG1396@1|root,COG1396@2|Bacteria,2HZR9@201174|Actinobacteria,4D1D2@85004|Bifidobacteriales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
IOLKFBCL_02065	1437610.BREU_1590	3.61e-226	630.0	COG3550@1|root,COG3550@2|Bacteria,2IA5Z@201174|Actinobacteria,4D1XC@85004|Bifidobacteriales	201174|Actinobacteria	S	Pfam:HipA_N	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
IOLKFBCL_02066	1437603.BMON_1239	3.74e-276	781.0	2DC0D@1|root,2ZC7A@2|Bacteria,2GJTX@201174|Actinobacteria,4D0Y0@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_02067	1437603.BMON_1238	7.48e-143	409.0	COG0395@1|root,COG0395@2|Bacteria,2GM2W@201174|Actinobacteria,4D05E@85004|Bifidobacteriales	201174|Actinobacteria	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
IOLKFBCL_02068	1437603.BMON_1237	6.88e-152	434.0	COG1175@1|root,COG1175@2|Bacteria,2GKJI@201174|Actinobacteria,4CZCI@85004|Bifidobacteriales	201174|Actinobacteria	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K10118	ko02010,map02010	M00196,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.28	-	-	BPD_transp_1
IOLKFBCL_02069	1437603.BMON_1236	1.61e-176	506.0	COG1653@1|root,COG1653@2|Bacteria,2HZAD@201174|Actinobacteria,4CZ9S@85004|Bifidobacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
IOLKFBCL_02070	1437609.BCAL_1438	2.08e-153	440.0	COG1609@1|root,COG1609@2|Bacteria,2GJDS@201174|Actinobacteria,4CZR6@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
IOLKFBCL_02071	216816.GS08_01850	4.43e-250	686.0	COG1957@1|root,COG1957@2|Bacteria,2GP6N@201174|Actinobacteria,4CZ0Y@85004|Bifidobacteriales	201174|Actinobacteria	F	Inosine-uridine preferring nucleoside hydrolase	-	-	3.2.2.1	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
IOLKFBCL_02072	216816.GS08_01845	4.08e-216	595.0	COG0667@1|root,COG0667@2|Bacteria,2GJ6R@201174|Actinobacteria,4CZB6@85004|Bifidobacteriales	201174|Actinobacteria	C	Oxidoreductase, aldo keto reductase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
IOLKFBCL_02073	326426.Bbr_0376a	1.32e-24	92.8	29W0J@1|root,30HIU@2|Bacteria,2HBEV@201174|Actinobacteria,4D2JK@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_02074	326426.Bbr_0375	4.95e-210	611.0	COG4907@1|root,COG4907@2|Bacteria,2HZD2@201174|Actinobacteria,4CZV5@85004|Bifidobacteriales	201174|Actinobacteria	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
IOLKFBCL_02075	216816.GS08_01830	1.1e-16	80.9	COG4907@1|root,COG4907@2|Bacteria,2HZD2@201174|Actinobacteria,4CZV5@85004|Bifidobacteriales	201174|Actinobacteria	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
IOLKFBCL_02076	216816.GS08_01830	0.0	1424.0	COG4907@1|root,COG4907@2|Bacteria,2HZD2@201174|Actinobacteria,4CZV5@85004|Bifidobacteriales	201174|Actinobacteria	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
IOLKFBCL_02077	216816.GS08_01825	1.03e-121	348.0	COG1704@1|root,COG1704@2|Bacteria,2GPS4@201174|Actinobacteria,4CZE2@85004|Bifidobacteriales	201174|Actinobacteria	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
IOLKFBCL_02078	216816.GS08_01820	3.17e-190	527.0	COG1117@1|root,COG1117@2|Bacteria,2GJQ3@201174|Actinobacteria,4CYVE@85004|Bifidobacteriales	201174|Actinobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
IOLKFBCL_02079	216816.GS08_01815	2.32e-215	597.0	COG0581@1|root,COG0581@2|Bacteria,2I2F2@201174|Actinobacteria,4D2UW@85004|Bifidobacteriales	201174|Actinobacteria	P	Phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
IOLKFBCL_02080	326426.Bbr_1681	3.53e-207	575.0	COG0573@1|root,COG0573@2|Bacteria,2GJDA@201174|Actinobacteria,4CYV0@85004|Bifidobacteriales	201174|Actinobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
IOLKFBCL_02081	216816.GS08_01805	1.09e-238	660.0	COG0226@1|root,COG0226@2|Bacteria,2GJXD@201174|Actinobacteria,4CYTZ@85004|Bifidobacteriales	201174|Actinobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
IOLKFBCL_02082	326426.Bbr_1683	1.68e-179	500.0	COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria,4CZTX@85004|Bifidobacteriales	201174|Actinobacteria	KT	Transcriptional regulatory protein, C terminal	regX3	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141	-	ko:K07776	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
IOLKFBCL_02083	216816.GS08_01795	1.89e-258	716.0	COG5002@1|root,COG5002@2|Bacteria,2GJY7@201174|Actinobacteria,4CZ42@85004|Bifidobacteriales	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	phoR	-	2.7.13.3	ko:K07636,ko:K07768	ko02020,map02020	M00434,M00443	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_4
IOLKFBCL_02084	216816.GS08_01790	2.91e-294	805.0	COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria,4CZFF@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
IOLKFBCL_02085	216816.GS08_01785	5.79e-157	441.0	COG0775@1|root,COG0775@2|Bacteria,2I8GZ@201174|Actinobacteria,4CYTM@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	mtnN	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
IOLKFBCL_02086	216816.GS08_01770	6.38e-298	812.0	COG0722@1|root,COG0722@2|Bacteria,2GMVF@201174|Actinobacteria,4CZ7I@85004|Bifidobacteriales	201174|Actinobacteria	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroG	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
IOLKFBCL_02087	216816.GS08_01765	1.27e-269	738.0	COG0722@1|root,COG0722@2|Bacteria,2GMVF@201174|Actinobacteria,4CZMR@85004|Bifidobacteriales	201174|Actinobacteria	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroG	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
IOLKFBCL_02088	216816.GS08_01760	0.0	905.0	COG3579@1|root,COG3579@2|Bacteria,2GNYU@201174|Actinobacteria,4CZDZ@85004|Bifidobacteriales	201174|Actinobacteria	E	Peptidase C1-like family	pepC2	-	3.4.22.40	ko:K01372	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C1_2
IOLKFBCL_02089	216816.GS08_01755	7.13e-155	459.0	COG1196@1|root,COG1196@2|Bacteria,2HZ99@201174|Actinobacteria,4CZ0S@85004|Bifidobacteriales	201174|Actinobacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	DivIVA
IOLKFBCL_02090	216816.GS08_01750	1.97e-158	444.0	COG2039@1|root,COG2039@2|Bacteria,2GN39@201174|Actinobacteria,4CZ57@85004|Bifidobacteriales	201174|Actinobacteria	O	Removes 5-oxoproline from various penultimate amino acid residues except L-proline	pcp	-	3.4.19.3	ko:K01304	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C15
IOLKFBCL_02091	216816.GS08_01745	2.62e-205	568.0	COG1211@1|root,COG1211@2|Bacteria,2GNHP@201174|Actinobacteria,4CYVZ@85004|Bifidobacteriales	201174|Actinobacteria	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	1.1.1.405,2.7.7.40,2.7.7.60	ko:K00991,ko:K21681	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	M00096	R01525,R02921,R05633	RC00002,RC00089	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,adh_short
IOLKFBCL_02092	216816.GS08_01740	5.04e-232	639.0	COG1496@1|root,COG1496@2|Bacteria,2GN1M@201174|Actinobacteria,4CZBI@85004|Bifidobacteriales	201174|Actinobacteria	Q	Multi-copper polyphenol oxidoreductase laccase	yfiH	GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
IOLKFBCL_02093	216816.GS08_01735	0.0	1075.0	COG0826@1|root,COG0826@2|Bacteria,2GKTB@201174|Actinobacteria,4CZA1@85004|Bifidobacteriales	201174|Actinobacteria	O	Peptidase family U32 C-terminal domain	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
IOLKFBCL_02094	216816.GS08_01730	4.51e-196	543.0	COG0336@1|root,COG0336@2|Bacteria,2GJ1G@201174|Actinobacteria,4CZ7A@85004|Bifidobacteriales	201174|Actinobacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	Acetyltransf_1,tRNA_m1G_MT
IOLKFBCL_02095	216816.GS08_01725	3.17e-135	384.0	COG0742@1|root,COG0742@2|Bacteria,2GQ3G@201174|Actinobacteria,4D0GU@85004|Bifidobacteriales	201174|Actinobacteria	L	Conserved hypothetical protein 95	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
IOLKFBCL_02096	158787.BSCA_0159	6.25e-74	229.0	COG3293@1|root,COG3293@2|Bacteria,2GX1N@201174|Actinobacteria,4D2D5@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_2
IOLKFBCL_02098	762211.BSTEL_0015	1.98e-34	132.0	COG1002@1|root,COG1002@2|Bacteria,2IA5I@201174|Actinobacteria,4D1CS@85004|Bifidobacteriales	201174|Actinobacteria	V	Type II restriction enzyme, methylase subunits	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
IOLKFBCL_02100	37659.JNLN01000001_gene503	2.19e-250	713.0	COG1874@1|root,COG1874@2|Bacteria,1TT9J@1239|Firmicutes,24CY9@186801|Clostridia,36G14@31979|Clostridiaceae	186801|Clostridia	G	Hypothetical glycosyl hydrolase 6	-	-	-	-	-	-	-	-	-	-	-	-	GHL6,Glyco_hydro_42M
IOLKFBCL_02101	543734.LCABL_29330	7.62e-126	376.0	COG0477@1|root,COG2814@2|Bacteria,1TQZ7@1239|Firmicutes,4HERG@91061|Bacilli,3F54C@33958|Lactobacillaceae	91061|Bacilli	EGP	Transporter, major facilitator family protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
IOLKFBCL_02102	547043.BIFPSEUDO_03223	1.08e-27	110.0	COG4948@1|root,COG4948@2|Bacteria,2GKSK@201174|Actinobacteria,4D0EI@85004|Bifidobacteriales	201174|Actinobacteria	M	Enolase C-terminal domain-like	-	-	4.2.1.68	ko:K18334	ko00051,ko01120,map00051,map01120	-	R03688	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
IOLKFBCL_02103	216816.GS08_01695	1.03e-60	198.0	COG4948@1|root,COG4948@2|Bacteria,2GKSK@201174|Actinobacteria,4D0EI@85004|Bifidobacteriales	201174|Actinobacteria	M	Enolase C-terminal domain-like	-	-	4.2.1.68	ko:K18334	ko00051,ko01120,map00051,map01120	-	R03688	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
IOLKFBCL_02104	216816.GS08_01690	1.07e-204	581.0	COG1653@1|root,COG1653@2|Bacteria,2I5GP@201174|Actinobacteria,4D2XQ@85004|Bifidobacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1
IOLKFBCL_02105	547043.BIFPSEUDO_03225	5.99e-219	605.0	COG0395@1|root,COG0395@2|Bacteria,2GJPZ@201174|Actinobacteria,4CZTQ@85004|Bifidobacteriales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
IOLKFBCL_02106	547043.BIFPSEUDO_03226	3.29e-205	569.0	COG1175@1|root,COG1175@2|Bacteria,2GMTW@201174|Actinobacteria,4CZW4@85004|Bifidobacteriales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
IOLKFBCL_02107	216816.GS08_01675	6.42e-89	269.0	COG1609@1|root,COG1609@2|Bacteria,2GJRG@201174|Actinobacteria,4CZI0@85004|Bifidobacteriales	201174|Actinobacteria	K	Bacterial regulatory proteins, lacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
IOLKFBCL_02108	216816.GS08_01670	0.0	1604.0	COG1200@1|root,COG1200@2|Bacteria,2GKA3@201174|Actinobacteria,4CYTV@85004|Bifidobacteriales	201174|Actinobacteria	L	helicase superfamily c-terminal domain	recG	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge,tRNA_anti-codon
IOLKFBCL_02109	216816.GS08_01665	3.03e-40	132.0	COG0227@1|root,COG0227@2|Bacteria,2GQNU@201174|Actinobacteria,4D17Q@85004|Bifidobacteriales	201174|Actinobacteria	J	Ribosomal L28 family	rpmB	GO:0003674,GO:0003735,GO:0005198	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
IOLKFBCL_02110	216816.GS08_01660	3.78e-249	683.0	COG0524@1|root,COG0524@2|Bacteria,2IA3T@201174|Actinobacteria,4CYSM@85004|Bifidobacteriales	201174|Actinobacteria	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH,PfkB
IOLKFBCL_02111	216816.GS08_01655	5.42e-293	801.0	COG2270@1|root,COG2270@2|Bacteria,2GJCW@201174|Actinobacteria,4CZU3@85004|Bifidobacteriales	201174|Actinobacteria	S	Vacuole effluxer Atg22 like	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
IOLKFBCL_02112	216816.GS08_01630	1.21e-245	676.0	COG1476@1|root,COG1476@2|Bacteria,2IBHI@201174|Actinobacteria,4CZ2T@85004|Bifidobacteriales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
IOLKFBCL_02113	216816.GS08_01625	3.04e-32	112.0	2BSWU@1|root,32N0G@2|Bacteria,2HA44@201174|Actinobacteria,4D2Q5@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_02114	326426.Bbr_1717	5.7e-15	73.2	2DQJC@1|root,33782@2|Bacteria,2I5YK@201174|Actinobacteria	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_02115	216816.GS08_01635	3.73e-33	115.0	COG2270@1|root,COG2270@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	yxiO	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
IOLKFBCL_02120	1437610.BREU_0523	3.38e-15	72.4	COG0431@1|root,COG0431@2|Bacteria,2GMA7@201174|Actinobacteria,4D163@85004|Bifidobacteriales	201174|Actinobacteria	S	NADPH-dependent FMN reductase	-	-	-	ko:K19784	-	-	-	-	ko00000	-	-	-	FMN_red
IOLKFBCL_02121	216816.GS08_01575	2.65e-110	318.0	COG0350@1|root,COG0350@2|Bacteria,2IHXW@201174|Actinobacteria,4D10F@85004|Bifidobacteriales	201174|Actinobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567,ko:K07443	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
IOLKFBCL_02122	216816.GS08_01570	1.93e-305	836.0	COG1073@1|root,COG1073@2|Bacteria,2GMT6@201174|Actinobacteria,4CZ4Q@85004|Bifidobacteriales	201174|Actinobacteria	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF2974
IOLKFBCL_02123	216816.GS08_01565	1.56e-173	484.0	COG1309@1|root,COG1309@2|Bacteria,2I8SX@201174|Actinobacteria,4CZXQ@85004|Bifidobacteriales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
IOLKFBCL_02124	216816.GS08_01560	0.0	928.0	COG1027@1|root,COG1027@2|Bacteria,2I2HG@201174|Actinobacteria,4CZ6N@85004|Bifidobacteriales	201174|Actinobacteria	E	Fumarase C C-terminus	aspA	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1
IOLKFBCL_02125	216816.GS08_01555	1.6e-177	496.0	COG0668@1|root,COG0668@2|Bacteria,2GZI1@201174|Actinobacteria,4CZ0A@85004|Bifidobacteriales	201174|Actinobacteria	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,cNMP_binding
IOLKFBCL_02126	216816.GS08_01550	9.53e-226	624.0	COG1266@1|root,COG1266@2|Bacteria,2I3DW@201174|Actinobacteria,4CZJZ@85004|Bifidobacteriales	201174|Actinobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
IOLKFBCL_02127	216816.GS08_01545	2.79e-292	800.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4CZPE@85004|Bifidobacteriales	201174|Actinobacteria	E	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	-	ko:K02052	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	ABC_tran,TOBE_2
IOLKFBCL_02128	216816.GS08_01540	5.75e-169	476.0	COG1177@1|root,COG1177@2|Bacteria,2GM0E@201174|Actinobacteria,4CZ2N@85004|Bifidobacteriales	201174|Actinobacteria	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02053	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
IOLKFBCL_02129	216816.GS08_01535	1.13e-202	563.0	COG4132@1|root,COG4132@2|Bacteria,2GNDF@201174|Actinobacteria,4CZHE@85004|Bifidobacteriales	201174|Actinobacteria	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02054	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
IOLKFBCL_02130	216816.GS08_01530	7.04e-267	732.0	COG1840@1|root,COG1840@2|Bacteria,2GJFH@201174|Actinobacteria,4CZHC@85004|Bifidobacteriales	201174|Actinobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02055	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	SBP_bac_6
IOLKFBCL_02131	216816.GS08_01525	1.17e-290	793.0	COG1181@1|root,COG1181@2|Bacteria,2GITC@201174|Actinobacteria,4CZ1R@85004|Bifidobacteriales	201174|Actinobacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddl	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008716,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
IOLKFBCL_02132	216816.GS08_01520	3.96e-228	629.0	COG0240@1|root,COG0240@2|Bacteria,2GJSD@201174|Actinobacteria,4CZHP@85004|Bifidobacteriales	201174|Actinobacteria	I	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
IOLKFBCL_02133	216816.GS08_01515	8.32e-229	631.0	COG0204@1|root,COG0204@2|Bacteria,2GKVA@201174|Actinobacteria,4CZG0@85004|Bifidobacteriales	201174|Actinobacteria	I	Phosphate acyltransferases	plsC2	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
IOLKFBCL_02134	216816.GS08_01510	1.33e-82	244.0	COG0251@1|root,COG0251@2|Bacteria,2IFCR@201174|Actinobacteria,4D0QD@85004|Bifidobacteriales	201174|Actinobacteria	J	Endoribonuclease L-PSP	psp1	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
IOLKFBCL_02136	216816.GS08_01500	9.16e-151	423.0	COG2954@1|root,COG2954@2|Bacteria,2GWD8@201174|Actinobacteria,4CZKD@85004|Bifidobacteriales	201174|Actinobacteria	S	CYTH	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_02137	216816.GS08_01495	1.7e-213	592.0	COG3118@1|root,COG3118@2|Bacteria,2GJ7B@201174|Actinobacteria,4CZHU@85004|Bifidobacteriales	201174|Actinobacteria	O	Tetratricopeptide repeat	ybbN	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
IOLKFBCL_02138	216816.GS08_01490	1.44e-231	638.0	28PR0@1|root,2ZCCY@2|Bacteria,2GNNZ@201174|Actinobacteria,4CYX7@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_02139	216816.GS08_01485	3.71e-240	662.0	2DMQ0@1|root,32SYI@2|Bacteria,2IA0N@201174|Actinobacteria,4CYQ0@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_02140	216816.GS08_01480	1.14e-205	572.0	COG0545@1|root,COG0545@2|Bacteria,2GJK2@201174|Actinobacteria,4CZEF@85004|Bifidobacteriales	201174|Actinobacteria	M	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
IOLKFBCL_02141	216816.GS08_01475	1.27e-174	488.0	COG1637@1|root,COG1637@2|Bacteria,2GIYB@201174|Actinobacteria,4CYXA@85004|Bifidobacteriales	201174|Actinobacteria	L	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures	nucS	-	-	ko:K07503	-	-	-	-	ko00000,ko01000	-	-	-	NucS
IOLKFBCL_02142	216816.GS08_01470	2.55e-65	198.0	COG0355@1|root,COG0355@2|Bacteria,2HZPJ@201174|Actinobacteria,4D16F@85004|Bifidobacteriales	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
IOLKFBCL_02143	216816.GS08_01465	0.0	966.0	COG0055@1|root,COG0055@2|Bacteria,2GIY6@201174|Actinobacteria,4CZGY@85004|Bifidobacteriales	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
IOLKFBCL_02144	216816.GS08_01460	3.68e-204	566.0	COG0224@1|root,COG0224@2|Bacteria,2GJ7Q@201174|Actinobacteria,4CYVJ@85004|Bifidobacteriales	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
IOLKFBCL_02145	216816.GS08_01455	0.0	1056.0	COG0056@1|root,COG0056@2|Bacteria,2GJRJ@201174|Actinobacteria,4CZI7@85004|Bifidobacteriales	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
IOLKFBCL_02146	216816.GS08_01450	6.56e-188	523.0	COG0712@1|root,COG0712@2|Bacteria,2GMJ5@201174|Actinobacteria,4CZ9V@85004|Bifidobacteriales	201174|Actinobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K02109,ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B,OSCP
IOLKFBCL_02147	216816.GS08_01445	1.74e-101	296.0	COG0711@1|root,COG0711@2|Bacteria,2GJS4@201174|Actinobacteria,4CYY5@85004|Bifidobacteriales	201174|Actinobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
IOLKFBCL_02148	1437608.BBIA_0293	4.22e-41	135.0	COG0636@1|root,COG0636@2|Bacteria,2GQI6@201174|Actinobacteria,4D16J@85004|Bifidobacteriales	201174|Actinobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
IOLKFBCL_02149	216816.GS08_01435	7.14e-188	522.0	COG0356@1|root,COG0356@2|Bacteria,2H3PR@201174|Actinobacteria,4CYZD@85004|Bifidobacteriales	201174|Actinobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
IOLKFBCL_02150	216816.GS08_01430	5.46e-261	713.0	COG1897@1|root,COG1897@2|Bacteria,2GK5E@201174|Actinobacteria,4CZRK@85004|Bifidobacteriales	201174|Actinobacteria	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metAA	-	2.3.1.46	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	M00017	R01777	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	HTS
IOLKFBCL_02151	1437610.BREU_0488	3.43e-29	107.0	COG2929@1|root,COG2929@2|Bacteria,2GW9X@201174|Actinobacteria,4D1SS@85004|Bifidobacteriales	201174|Actinobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
IOLKFBCL_02152	1403948.Q618_VCMC00001G0002	7.25e-19	80.9	2E3TC@1|root,32DPP@2|Bacteria,2GU2H@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_02155	1196028.ALEF01000049_gene314	2.34e-31	129.0	COG1874@1|root,COG1874@2|Bacteria,1TT9J@1239|Firmicutes,4HFG2@91061|Bacilli	91061|Bacilli	G	beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	GHL6,Glyco_hydro_42M
IOLKFBCL_02157	158787.BSCA_0159	1.21e-22	93.6	COG3293@1|root,COG3293@2|Bacteria,2GX1N@201174|Actinobacteria,4D2D5@85004|Bifidobacteriales	201174|Actinobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_2
IOLKFBCL_02158	290402.Cbei_2683	1.43e-96	288.0	COG1073@1|root,COG1073@2|Bacteria,1U9AI@1239|Firmicutes,24B6Z@186801|Clostridia,36F9A@31979|Clostridiaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
IOLKFBCL_02159	216816.GS08_01420	0.0	1150.0	COG5624@1|root,COG5624@2|Bacteria,2H7AK@201174|Actinobacteria,4CZMA@85004|Bifidobacteriales	201174|Actinobacteria	K	RNA polymerase II activating transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_02160	216816.GS08_01415	0.0	1462.0	COG0366@1|root,COG0366@2|Bacteria,2GJKR@201174|Actinobacteria,4CZSK@85004|Bifidobacteriales	201174|Actinobacteria	G	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB	glgE	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.4.99.16	ko:K16147	ko00500,ko01100,map00500,map01100	-	R09994	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3416
IOLKFBCL_02161	216816.GS08_01410	9.28e-118	336.0	COG0221@1|root,COG0221@2|Bacteria,2GM7F@201174|Actinobacteria,4CYWS@85004|Bifidobacteriales	201174|Actinobacteria	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	GO:0000287,GO:0003674,GO:0003824,GO:0004427,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0071944	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3628	Pyrophosphatase
IOLKFBCL_02162	326426.Bbr_0294	1.93e-126	360.0	COG1971@1|root,COG1971@2|Bacteria,2GNBU@201174|Actinobacteria,4D01X@85004|Bifidobacteriales	201174|Actinobacteria	P	Probably functions as a manganese efflux pump	mntP	-	-	-	-	-	-	-	-	-	-	-	Mntp
IOLKFBCL_02163	216816.GS08_01400	4.85e-120	348.0	2A0I6@1|root,30NNB@2|Bacteria,2GJ8M@201174|Actinobacteria,4D0ZN@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_02164	216816.GS08_01395	5.65e-177	494.0	COG0745@1|root,COG0745@2|Bacteria,2GJGU@201174|Actinobacteria,4CZB9@85004|Bifidobacteriales	201174|Actinobacteria	KT	Transcriptional regulatory protein, C terminal	glnR	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
IOLKFBCL_02165	216816.GS08_01390	2.81e-164	459.0	COG0177@1|root,COG0177@2|Bacteria,2GJ01@201174|Actinobacteria,4CZ31@85004|Bifidobacteriales	201174|Actinobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
IOLKFBCL_02166	216816.GS08_01385	0.0	963.0	COG0747@1|root,COG0747@2|Bacteria,2GM5G@201174|Actinobacteria,4CYUZ@85004|Bifidobacteriales	201174|Actinobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
IOLKFBCL_02167	216816.GS08_01380	0.0	1852.0	COG0525@1|root,COG0525@2|Bacteria,2GK8H@201174|Actinobacteria,4CYVG@85004|Bifidobacteriales	201174|Actinobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
IOLKFBCL_02168	216816.GS08_01375	0.0	1086.0	COG1511@1|root,COG1511@2|Bacteria,2I9PN@201174|Actinobacteria,4CZC2@85004|Bifidobacteriales	201174|Actinobacteria	S	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_02169	216816.GS08_01370	6.34e-81	240.0	COG1605@1|root,COG1605@2|Bacteria,2IQ46@201174|Actinobacteria,4D12A@85004|Bifidobacteriales	201174|Actinobacteria	E	Chorismate mutase type II	tyrA	-	5.4.99.5	ko:K04092	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2
IOLKFBCL_02170	216816.GS08_01360	0.0	1055.0	COG1158@1|root,COG1158@2|Bacteria,2GIWY@201174|Actinobacteria,4CZ2Z@85004|Bifidobacteriales	201174|Actinobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006360,GO:0006363,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
IOLKFBCL_02171	216816.GS08_01355	0.0	1100.0	COG1232@1|root,COG1232@2|Bacteria,2HZ9K@201174|Actinobacteria,4CZ3Z@85004|Bifidobacteriales	201174|Actinobacteria	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
IOLKFBCL_02172	1437610.BREU_0470	0.0	946.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	3.1.3.2,3.6.1.27	ko:K09474,ko:K12685,ko:K19302	ko00550,ko00740,ko01100,ko02020,map00550,map00740,map01100,map02020	-	R00548,R05627	RC00002,RC00017	ko00000,ko00001,ko01000,ko01011,ko02000,ko02044	1.B.12.5.1,1.B.12.5.3	-	-	Autotransporter,LssY_C,PAP2,PATR,YjbH
IOLKFBCL_02173	216816.GS08_01350	2.66e-68	206.0	2AFXT@1|root,3161G@2|Bacteria,2IKPZ@201174|Actinobacteria,4D0UV@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF2469)	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF2469
IOLKFBCL_02174	216816.GS08_01345	6.53e-249	684.0	COG1670@1|root,COG1670@2|Bacteria,2I2GV@201174|Actinobacteria,4CYPW@85004|Bifidobacteriales	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
IOLKFBCL_02175	216816.GS08_01340	0.0	985.0	COG0064@1|root,COG0064@2|Bacteria,2GJJH@201174|Actinobacteria,4CYUY@85004|Bifidobacteriales	201174|Actinobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
IOLKFBCL_02176	216816.GS08_01335	0.0	990.0	COG0154@1|root,COG0154@2|Bacteria,2GJK5@201174|Actinobacteria,4CZ1X@85004|Bifidobacteriales	201174|Actinobacteria	F	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	GO:0008150,GO:0040007	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
IOLKFBCL_02177	398513.BBNG_01427	1.47e-67	205.0	COG0721@1|root,COG0721@2|Bacteria,2IQJN@201174|Actinobacteria,4D10U@85004|Bifidobacteriales	201174|Actinobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
IOLKFBCL_02178	216816.GS08_01325	4.69e-235	646.0	COG5340@1|root,COG5340@2|Bacteria,2ICPH@201174|Actinobacteria,4CZJ7@85004|Bifidobacteriales	201174|Actinobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_02179	216816.GS08_01320	8.81e-204	563.0	COG0566@1|root,COG0566@2|Bacteria,2GM1A@201174|Actinobacteria,4CZE8@85004|Bifidobacteriales	201174|Actinobacteria	J	RNA methyltransferase TrmH family	trmH	-	2.1.1.34	ko:K00556	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
IOLKFBCL_02180	1437610.BREU_0461	4.22e-127	363.0	COG0461@1|root,COG0461@2|Bacteria,2HZDS@201174|Actinobacteria,4CZZ6@85004|Bifidobacteriales	201174|Actinobacteria	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE1	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_02181	216816.GS08_01310	1.29e-279	771.0	COG1322@1|root,COG1322@2|Bacteria,2GP4U@201174|Actinobacteria,4CZA5@85004|Bifidobacteriales	201174|Actinobacteria	S	RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
IOLKFBCL_02182	216816.GS08_01305	5.5e-56	174.0	COG1937@1|root,COG1937@2|Bacteria,2IQAC@201174|Actinobacteria,4D1A2@85004|Bifidobacteriales	201174|Actinobacteria	S	Metal-sensitive transcriptional repressor	csoR	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010035,GO:0010038,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0042221,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0046688,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
IOLKFBCL_02183	216816.GS08_01300	0.0	1645.0	COG2217@1|root,COG4633@1|root,COG2217@2|Bacteria,COG4633@2|Bacteria,2GIRF@201174|Actinobacteria,4CZ24@85004|Bifidobacteriales	201174|Actinobacteria	P	E1-E2 ATPase	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	Cupredoxin_1,E1-E2_ATPase,HMA,Hydrolase,YHS
IOLKFBCL_02184	326426.Bbr_0267	2.03e-165	463.0	COG0580@1|root,COG0580@2|Bacteria,2GKK3@201174|Actinobacteria,4CZ7F@85004|Bifidobacteriales	201174|Actinobacteria	U	Belongs to the MIP aquaporin (TC 1.A.8) family	glpF	-	-	ko:K02440	-	-	-	-	ko00000,ko02000	1.A.8.1,1.A.8.2	-	-	MIP
IOLKFBCL_02185	1206741.BAFX01000049_gene2152	3.79e-09	59.7	COG0629@1|root,COG0629@2|Bacteria,2HWSA@201174|Actinobacteria,4G24N@85025|Nocardiaceae	201174|Actinobacteria	L	Single-strand binding protein family	-	-	-	-	-	-	-	-	-	-	-	-	SSB
IOLKFBCL_02186	1416759.AYMR01000006_gene1028	4.61e-94	292.0	COG3669@1|root,COG3669@2|Bacteria,2HUEI@201174|Actinobacteria,4FRB2@85023|Microbacteriaceae	201174|Actinobacteria	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C
IOLKFBCL_02187	216816.GS08_10065	5.18e-218	603.0	COG2852@1|root,COG2852@2|Bacteria,2HTNX@201174|Actinobacteria,4D0CP@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_02188	1437610.BREU_2276	0.0	957.0	COG3579@1|root,COG3579@2|Bacteria,2HCVR@201174|Actinobacteria,4CZD8@85004|Bifidobacteriales	201174|Actinobacteria	E	Peptidase C1-like family	-	-	3.4.22.40	ko:K01372	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C1_2
IOLKFBCL_02189	216816.GS08_10055	1.23e-228	630.0	COG0601@1|root,COG0601@2|Bacteria,2GJ2C@201174|Actinobacteria,4CYS5@85004|Bifidobacteriales	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	oppB1	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
IOLKFBCL_02190	1437610.BREU_2279	7.07e-226	624.0	COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria,4CYQF@85004|Bifidobacteriales	201174|Actinobacteria	EP	N-terminal TM domain of oligopeptide transport permease C	oppC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
IOLKFBCL_02191	1437610.BREU_2280	0.0	1387.0	COG1123@1|root,COG4172@2|Bacteria,2H3HY@201174|Actinobacteria,4CYU0@85004|Bifidobacteriales	201174|Actinobacteria	P	Belongs to the ABC transporter superfamily	oppD	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
IOLKFBCL_02192	216816.GS08_10040	0.0	1115.0	COG0747@1|root,COG0747@2|Bacteria,2GJ9N@201174|Actinobacteria,4CZ3S@85004|Bifidobacteriales	201174|Actinobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	oppA	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
IOLKFBCL_02194	216816.GS08_10035	0.0	881.0	COG0477@1|root,COG0477@2|Bacteria,2I3AP@201174|Actinobacteria,4D0YC@85004|Bifidobacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
IOLKFBCL_02195	216816.GS08_10030	0.0	915.0	COG1373@1|root,COG1373@2|Bacteria,2HCYQ@201174|Actinobacteria,4D2TP@85004|Bifidobacteriales	201174|Actinobacteria	S	AAA domain	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
IOLKFBCL_02196	216816.GS08_10025	0.0	1425.0	COG1874@1|root,COG1874@2|Bacteria,2GMDT@201174|Actinobacteria,4CZ6K@85004|Bifidobacteriales	201174|Actinobacteria	G	Beta-galactosidase trimerisation domain	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
IOLKFBCL_02197	216816.GS08_10020	5.34e-245	673.0	COG1609@1|root,COG1609@2|Bacteria,2GJ5Q@201174|Actinobacteria,4D041@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
IOLKFBCL_02198	216816.GS08_10015	4.55e-305	831.0	COG1653@1|root,COG1653@2|Bacteria,2HZAD@201174|Actinobacteria,4CZ9S@85004|Bifidobacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_8
IOLKFBCL_02199	1437610.BREU_2296	9.38e-229	630.0	COG1175@1|root,COG1175@2|Bacteria,2GKJI@201174|Actinobacteria,4CZCI@85004|Bifidobacteriales	201174|Actinobacteria	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K10118	ko02010,map02010	M00196,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.28	-	-	BPD_transp_1
IOLKFBCL_02200	1437610.BREU_2297	2.58e-196	545.0	COG0395@1|root,COG0395@2|Bacteria,2GM2W@201174|Actinobacteria,4D05E@85004|Bifidobacteriales	201174|Actinobacteria	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
IOLKFBCL_02201	216816.GS08_10000	6.08e-247	676.0	COG3507@1|root,COG3507@2|Bacteria,2I2H2@201174|Actinobacteria,4CZDP@85004|Bifidobacteriales	201174|Actinobacteria	G	Glycosyl hydrolases family 43	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
IOLKFBCL_02202	326426.Bbr_1812	0.0	872.0	COG1373@1|root,COG1373@2|Bacteria,2GM3Y@201174|Actinobacteria,4CZTJ@85004|Bifidobacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
IOLKFBCL_02203	216816.GS08_09990	0.0	923.0	COG1672@1|root,COG1672@2|Bacteria,2GMAZ@201174|Actinobacteria,4CZTD@85004|Bifidobacteriales	201174|Actinobacteria	S	ATPase domain predominantly from Archaea	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	ATPase_2,DUF234
IOLKFBCL_02204	1437610.BREU_1221	0.0	1231.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4D028@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
IOLKFBCL_02205	1437610.BREU_1220	0.0	1149.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4CZ32@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
IOLKFBCL_02206	1437610.BREU_1219	2.28e-250	687.0	COG3177@1|root,COG3177@2|Bacteria,2IAAQ@201174|Actinobacteria,4CZAM@85004|Bifidobacteriales	201174|Actinobacteria	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
IOLKFBCL_02207	216816.GS08_09855	2.72e-237	651.0	COG0084@1|root,COG0084@2|Bacteria,2GMJJ@201174|Actinobacteria,4CYZI@85004|Bifidobacteriales	201174|Actinobacteria	L	TatD related DNase	tatD	GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
IOLKFBCL_02208	216816.GS08_09850	0.0	1556.0	COG3158@1|root,COG3158@2|Bacteria,2GMPQ@201174|Actinobacteria,4CZM3@85004|Bifidobacteriales	201174|Actinobacteria	P	Transport of potassium into the cell	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
IOLKFBCL_02209	216816.GS08_09845	1.2e-203	563.0	COG0121@1|root,COG0121@2|Bacteria,2IBFV@201174|Actinobacteria,4CYX2@85004|Bifidobacteriales	201174|Actinobacteria	S	Glutamine amidotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	GATase_6
IOLKFBCL_02210	216816.GS08_09840	1.57e-173	483.0	COG2206@1|root,COG2206@2|Bacteria,2GNQR@201174|Actinobacteria,4CYT9@85004|Bifidobacteriales	201174|Actinobacteria	T	HD domain	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
IOLKFBCL_02212	216816.GS08_09830	8.74e-243	670.0	COG1136@1|root,COG1136@2|Bacteria,2GNFW@201174|Actinobacteria,4CZAW@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IOLKFBCL_02213	216816.GS08_09825	1.17e-300	827.0	COG0577@1|root,COG0577@2|Bacteria,2GMGJ@201174|Actinobacteria,4CZBN@85004|Bifidobacteriales	201174|Actinobacteria	V	ABC transporter permease	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
IOLKFBCL_02214	216816.GS08_09820	0.0	1312.0	COG2976@1|root,COG2976@2|Bacteria,2GNIS@201174|Actinobacteria,4D2V4@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF4012)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4012
IOLKFBCL_02215	216816.GS08_09815	4.18e-245	678.0	COG1835@1|root,COG1835@2|Bacteria,2H65A@201174|Actinobacteria,4D2BH@85004|Bifidobacteriales	201174|Actinobacteria	I	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_02216	702459.BBPR_0050	3.27e-256	701.0	COG1088@1|root,COG1088@2|Bacteria,2GNDU@201174|Actinobacteria,4CZZY@85004|Bifidobacteriales	201174|Actinobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3464	GDP_Man_Dehyd
IOLKFBCL_02217	518635.BIFANG_02121	0.0	1103.0	COG1216@1|root,COG1216@2|Bacteria,2GM9N@201174|Actinobacteria,4CZ30@85004|Bifidobacteriales	201174|Actinobacteria	S	Glycosyltransferase like family 2	glfT	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0006139,GO:0006629,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008378,GO:0008610,GO:0008653,GO:0008921,GO:0009058,GO:0009059,GO:0009103,GO:0009225,GO:0009273,GO:0009987,GO:0010383,GO:0016020,GO:0016043,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0022607,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0035250,GO:0035496,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045229,GO:0046483,GO:0052573,GO:0055086,GO:0070589,GO:0070592,GO:0071554,GO:0071555,GO:0071704,GO:0071766,GO:0071769,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901576,GO:1903509	2.4.1.288	ko:K16650	-	-	-	-	ko00000,ko01000,ko01003	-	GT2	iNJ661.Rv3808c	Glyco_tranf_2_3
IOLKFBCL_02218	1437605.BACT_1233	2.37e-213	600.0	COG1134@1|root,COG1134@2|Bacteria,2GIVF@201174|Actinobacteria,4CZ1B@85004|Bifidobacteriales	201174|Actinobacteria	GM	ABC transporter, ATP-binding protein	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,Wzt_C
IOLKFBCL_02219	1437600.JDUI01000010_gene163	1.48e-131	380.0	COG1682@1|root,COG1682@2|Bacteria,2GP5K@201174|Actinobacteria,4CZ73@85004|Bifidobacteriales	201174|Actinobacteria	U	Transport permease protein	tagG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
IOLKFBCL_02220	1437605.BACT_1237	9.53e-166	470.0	COG1216@1|root,COG1216@2|Bacteria,2GMQQ@201174|Actinobacteria,4CZRJ@85004|Bifidobacteriales	201174|Actinobacteria	S	Glycosyltransferase, group 2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
IOLKFBCL_02221	1437606.BBOH_0850	6.94e-229	652.0	COG0438@1|root,COG0438@2|Bacteria,2HZC4@201174|Actinobacteria,4CZPF@85004|Bifidobacteriales	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
IOLKFBCL_02222	43354.JOIJ01000002_gene4232	5.8e-70	232.0	COG2327@1|root,COG2327@2|Bacteria,2H0DT@201174|Actinobacteria,4E1Q8@85010|Pseudonocardiales	201174|Actinobacteria	S	Polysaccharide pyruvyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
IOLKFBCL_02223	216816.GS08_09745	2.38e-215	596.0	COG0463@1|root,COG0463@2|Bacteria,2I2GR@201174|Actinobacteria,4CZTN@85004|Bifidobacteriales	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
IOLKFBCL_02224	1437606.BBOH_0859	9.1e-234	672.0	COG5617@1|root,COG5617@2|Bacteria,2HKW0@201174|Actinobacteria	201174|Actinobacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_02225	1680.BADO_1514	3.47e-197	555.0	COG3274@1|root,COG3274@2|Bacteria,2I2GS@201174|Actinobacteria,4D1N3@85004|Bifidobacteriales	201174|Actinobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
IOLKFBCL_02226	216816.GS08_09745	1.43e-06	50.8	COG0463@1|root,COG0463@2|Bacteria,2I2GR@201174|Actinobacteria,4CZTN@85004|Bifidobacteriales	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
IOLKFBCL_02227	158787.BSCA_1802	4.13e-220	617.0	COG1653@1|root,COG1653@2|Bacteria,2GJSR@201174|Actinobacteria,4D08C@85004|Bifidobacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
IOLKFBCL_02228	158787.BSCA_1685	1.67e-154	442.0	COG1175@1|root,COG1175@2|Bacteria,2GKJI@201174|Actinobacteria,4D0DM@85004|Bifidobacteriales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K17330	ko02010,map02010	M00207,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.33	-	-	BPD_transp_1
IOLKFBCL_02229	158787.BSCA_1686	9.45e-161	454.0	COG0395@1|root,COG0395@2|Bacteria,2GMTH@201174|Actinobacteria,4D014@85004|Bifidobacteriales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
IOLKFBCL_02230	1437600.JDUI01000013_gene970	1.15e-231	646.0	COG3934@1|root,COG3934@2|Bacteria,2GNN6@201174|Actinobacteria,4CZEH@85004|Bifidobacteriales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
IOLKFBCL_02231	326426.Bbr_1786	2.26e-283	774.0	COG0562@1|root,COG0562@2|Bacteria,2GK2Z@201174|Actinobacteria,4CZ2W@85004|Bifidobacteriales	201174|Actinobacteria	M	UDP-galactopyranose mutase	glf	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008767,GO:0009273,GO:0009987,GO:0016020,GO:0016853,GO:0016866,GO:0030312,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071766,GO:0071840,GO:0071944	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3809c	GLF,NAD_binding_8
IOLKFBCL_02232	216816.GS08_09690	9.89e-201	555.0	COG0179@1|root,COG0179@2|Bacteria,2GN2G@201174|Actinobacteria,4CZH5@85004|Bifidobacteriales	201174|Actinobacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
IOLKFBCL_02233	1235793.C809_03973	5.77e-94	279.0	COG0454@1|root,COG0456@2|Bacteria,1V125@1239|Firmicutes,24J9E@186801|Clostridia,27NET@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	2.3.1.57	ko:K03826,ko:K22441	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
IOLKFBCL_02234	216816.GS08_09670	0.0	1607.0	COG0542@1|root,COG0542@2|Bacteria,2GJ73@201174|Actinobacteria,4CZDY@85004|Bifidobacteriales	201174|Actinobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
IOLKFBCL_02235	216816.GS08_09665	2.77e-198	556.0	COG0008@1|root,COG0008@2|Bacteria,2GKMT@201174|Actinobacteria,4CYRY@85004|Bifidobacteriales	201174|Actinobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	gluQ	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
IOLKFBCL_02236	1437610.BREU_1166	3.69e-200	561.0	COG0584@1|root,COG0584@2|Bacteria,2GNM5@201174|Actinobacteria,4CYS4@85004|Bifidobacteriales	201174|Actinobacteria	C	Glycerophosphoryl diester phosphodiesterase family	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,Laminin_G_3
IOLKFBCL_02237	1437608.BBIA_0149	2.38e-167	474.0	COG1175@1|root,COG1175@2|Bacteria,2GKJI@201174|Actinobacteria,4D0GQ@85004|Bifidobacteriales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K05814	ko02010,map02010	M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3	-	-	BPD_transp_1
IOLKFBCL_02238	1437608.BBIA_0148	1.02e-162	462.0	COG0395@1|root,COG0395@2|Bacteria,2GMTH@201174|Actinobacteria,4D29F@85004|Bifidobacteriales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026,ko:K05815	ko02010,map02010	M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3	-	-	BPD_transp_1
IOLKFBCL_02239	1437608.BBIA_0147	4.61e-262	726.0	COG1653@1|root,COG1653@2|Bacteria,2GNYN@201174|Actinobacteria,4D08X@85004|Bifidobacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027,ko:K17329	ko02010,map02010	M00207,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.33	-	-	SBP_bac_1,SBP_bac_8
IOLKFBCL_02240	216816.GS08_09660	1.47e-129	375.0	COG0584@1|root,COG0584@2|Bacteria,2GNM5@201174|Actinobacteria,4CYS4@85004|Bifidobacteriales	201174|Actinobacteria	C	Glycerophosphoryl diester phosphodiesterase family	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,Laminin_G_3
IOLKFBCL_02241	518635.BIFANG_02077	1.31e-92	272.0	COG1576@1|root,COG1576@2|Bacteria,2IJE0@201174|Actinobacteria,4D0P5@85004|Bifidobacteriales	201174|Actinobacteria	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
IOLKFBCL_02242	326426.Bbr_1777	2.23e-149	420.0	COG0035@1|root,COG0035@2|Bacteria,2GPJE@201174|Actinobacteria,4CYVS@85004|Bifidobacteriales	201174|Actinobacteria	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
IOLKFBCL_02243	1437610.BREU_1163	2.48e-272	762.0	COG0671@1|root,COG0671@2|Bacteria,2I4ZG@201174|Actinobacteria,4CZ80@85004|Bifidobacteriales	201174|Actinobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2,Phytase-like
IOLKFBCL_02244	561180.BIFGAL_03114	3.19e-53	172.0	COG2452@1|root,COG2452@2|Bacteria,2IDNQ@201174|Actinobacteria,4CZVV@85004|Bifidobacteriales	201174|Actinobacteria	L	Resolvase, N terminal domain	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K07450	-	-	-	-	ko00000	-	-	-	Resolvase
IOLKFBCL_02245	1437610.BREU_0047	1.8e-168	484.0	COG0675@1|root,COG0675@2|Bacteria,2GM6K@201174|Actinobacteria,4CZ11@85004|Bifidobacteriales	201174|Actinobacteria	L	Helix-turn-helix domain	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
IOLKFBCL_02246	326426.Bbr_1322	9.87e-122	347.0	COG4283@1|root,COG4283@2|Bacteria,2IGS2@201174|Actinobacteria,4D14I@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF1706)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1706
IOLKFBCL_02247	1280689.AUJC01000006_gene2766	1.73e-161	463.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,36DYU@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10112,ko:K17240	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00599,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.38	-	-	ABC_tran,TOBE_2
IOLKFBCL_02248	1415775.U729_2176	8.36e-130	378.0	COG1175@1|root,COG1175@2|Bacteria,1TREE@1239|Firmicutes,24B75@186801|Clostridia,36HHS@31979|Clostridiaceae	186801|Clostridia	G	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
IOLKFBCL_02249	1415775.U729_2175	8.5e-128	370.0	COG0395@1|root,COG0395@2|Bacteria,1TRCP@1239|Firmicutes,25C50@186801|Clostridia,36WPD@31979|Clostridiaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026,ko:K05815	ko02010,map02010	M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3	-	-	BPD_transp_1
IOLKFBCL_02250	1280692.AUJL01000016_gene1145	1.43e-144	426.0	COG0595@1|root,COG0595@2|Bacteria,1V0AV@1239|Firmicutes,24AT4@186801|Clostridia,36EN7@31979|Clostridiaceae	186801|Clostridia	S	Metallo-beta-lactamase superfamily	-	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B_2,RMMBL
IOLKFBCL_02251	1415775.U729_2173	1.21e-174	501.0	COG1653@1|root,COG1653@2|Bacteria,1TS64@1239|Firmicutes,249GC@186801|Clostridia,36DXR@31979|Clostridiaceae	186801|Clostridia	G	Extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_8
IOLKFBCL_02252	595593.JREV01000021_gene1745	8.77e-38	139.0	COG0546@1|root,COG0546@2|Bacteria,2IQ6G@201174|Actinobacteria	201174|Actinobacteria	S	phosphoglycolate phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	HAD
IOLKFBCL_02253	1437609.BCAL_0598	2.27e-153	455.0	COG3525@1|root,COG3525@2|Bacteria,2HZCI@201174|Actinobacteria,4CZS1@85004|Bifidobacteriales	201174|Actinobacteria	G	Glycosyl hydrolase family 20, domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_20,Glyco_hydro_20b
IOLKFBCL_02254	326426.Bbr_1556	7.69e-60	207.0	COG3525@1|root,COG3525@2|Bacteria,2HZCI@201174|Actinobacteria,4CZS1@85004|Bifidobacteriales	201174|Actinobacteria	G	Glycosyl hydrolase family 20, domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_20,Glyco_hydro_20b
IOLKFBCL_02255	1435051.BMOU_0550	1.04e-279	776.0	COG1653@1|root,COG1653@2|Bacteria,2I8SG@201174|Actinobacteria,4CZ4S@85004|Bifidobacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K17318	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	SBP_bac_1,SBP_bac_8
IOLKFBCL_02256	1435051.BMOU_0550	6.43e-284	787.0	COG1653@1|root,COG1653@2|Bacteria,2I8SG@201174|Actinobacteria,4CZ4S@85004|Bifidobacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K17318	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	SBP_bac_1,SBP_bac_8
IOLKFBCL_02257	1435051.BMOU_0550	7.8e-314	863.0	COG1653@1|root,COG1653@2|Bacteria,2I8SG@201174|Actinobacteria,4CZ4S@85004|Bifidobacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K17318	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	SBP_bac_1,SBP_bac_8
IOLKFBCL_02258	1688.BCUN_0027	5.84e-172	486.0	COG0329@1|root,COG0329@2|Bacteria,2GJDB@201174|Actinobacteria,4D04B@85004|Bifidobacteriales	201174|Actinobacteria	EM	Dihydrodipicolinate synthetase family	nanA	-	4.1.3.3,4.3.3.7	ko:K01639,ko:K01714	ko00261,ko00300,ko00520,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00520,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R01811,R10147	RC00159,RC00600,RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
IOLKFBCL_02259	398513.BBNG_01313	4.24e-149	450.0	COG1470@1|root,COG4409@1|root,COG1470@2|Bacteria,COG4409@2|Bacteria,2I0CJ@201174|Actinobacteria,4D02H@85004|Bifidobacteriales	201174|Actinobacteria	G	BNR repeat-like domain	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,CW_binding_1,F5_F8_type_C,NPCBM_assoc
IOLKFBCL_02260	1435051.BMOU_0550	1.56e-295	816.0	COG1653@1|root,COG1653@2|Bacteria,2I8SG@201174|Actinobacteria,4CZ4S@85004|Bifidobacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K17318	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	SBP_bac_1,SBP_bac_8
IOLKFBCL_02261	1435051.BMOU_0549	2.2e-192	538.0	COG4209@1|root,COG4209@2|Bacteria,2GKSR@201174|Actinobacteria,4CZIC@85004|Bifidobacteriales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17319	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
IOLKFBCL_02262	1435051.BMOU_0548	1.39e-194	543.0	COG0395@1|root,COG0395@2|Bacteria,2GJPQ@201174|Actinobacteria,4CYTJ@85004|Bifidobacteriales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17320	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
IOLKFBCL_02263	1435051.BMOU_0546	2.97e-123	355.0	COG5578@1|root,COG5578@2|Bacteria,2H1AM@201174|Actinobacteria,4CYSQ@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function, DUF624	-	-	-	-	-	-	-	-	-	-	-	-	DUF624
IOLKFBCL_02264	547043.BIFPSEUDO_03223	5.38e-309	842.0	COG4948@1|root,COG4948@2|Bacteria,2GKSK@201174|Actinobacteria,4D0EI@85004|Bifidobacteriales	201174|Actinobacteria	M	Enolase C-terminal domain-like	-	-	4.2.1.68	ko:K18334	ko00051,ko01120,map00051,map01120	-	R03688	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
IOLKFBCL_02265	216816.GS08_01700	1.05e-181	506.0	COG1028@1|root,COG1028@2|Bacteria,2GJGM@201174|Actinobacteria,4CZXI@85004|Bifidobacteriales	201174|Actinobacteria	IQ	KR domain	-	-	1.1.1.100,1.1.1.413	ko:K00059,ko:K18333,ko:K22322	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R08926,R10116,R10120,R11671	RC00029,RC00066,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
IOLKFBCL_02266	216816.GS08_01705	2.56e-195	543.0	COG0329@1|root,COG0329@2|Bacteria,2GJDB@201174|Actinobacteria,4D04B@85004|Bifidobacteriales	201174|Actinobacteria	EM	Dihydrodipicolinate synthetase family	-	-	4.1.2.28	ko:K22397	ko00040,map00040	-	R01782	RC00307,RC00572	ko00000,ko00001,ko01000	-	-	-	DHDPS
IOLKFBCL_02267	216816.GS08_01710	1.8e-90	266.0	COG4154@1|root,COG4154@2|Bacteria,2INSY@201174|Actinobacteria,4D122@85004|Bifidobacteriales	201174|Actinobacteria	G	RbsD / FucU transport protein family	fucU	-	5.1.3.29	ko:K02431	-	-	R10764	RC00563	ko00000,ko01000	-	-	-	RbsD_FucU
IOLKFBCL_02268	216816.GS08_01715	0.0	888.0	COG3669@1|root,COG3669@2|Bacteria,2I650@201174|Actinobacteria,4CZPN@85004|Bifidobacteriales	201174|Actinobacteria	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,F5_F8_type_C
IOLKFBCL_02269	216816.GS08_01720	0.0	1287.0	COG1554@1|root,COG1554@2|Bacteria,2GJXJ@201174|Actinobacteria,4CZZK@85004|Bifidobacteriales	201174|Actinobacteria	G	Glycosyl hydrolase family 65, N-terminal domain	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	Big_2,Big_3,Glyco_hyd_65N_2
IOLKFBCL_02270	216816.GS08_03895	0.0	2101.0	COG3250@1|root,COG3250@2|Bacteria,2GMAT@201174|Actinobacteria,4CYYS@85004|Bifidobacteriales	201174|Actinobacteria	G	Psort location Cytoplasmic, score 8.87	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Laminin_G_3
IOLKFBCL_02271	216816.GS08_03900	0.0	935.0	COG2211@1|root,COG2211@2|Bacteria,2HD4Y@201174|Actinobacteria,4CZRA@85004|Bifidobacteriales	201174|Actinobacteria	G	Psort location CytoplasmicMembrane, score 10.00	gph	-	-	ko:K16209	-	-	-	-	ko00000,ko02000	2.A.2.2	-	-	MFS_2
IOLKFBCL_02272	216816.GS08_03905	0.0	903.0	COG2211@1|root,COG2211@2|Bacteria,2HD4Y@201174|Actinobacteria,4CZRA@85004|Bifidobacteriales	201174|Actinobacteria	G	Psort location CytoplasmicMembrane, score 10.00	gph	-	-	ko:K16209	-	-	-	-	ko00000,ko02000	2.A.2.2	-	-	MFS_2
IOLKFBCL_02273	216816.GS08_09640	2.33e-174	488.0	28MMU@1|root,2ZAXG@2|Bacteria,2HAD5@201174|Actinobacteria,4CZ1Q@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IOLKFBCL_02274	216816.GS08_09635	1.53e-288	788.0	COG0494@1|root,COG2062@1|root,COG0494@2|Bacteria,COG2062@2|Bacteria,2GNRV@201174|Actinobacteria,4CZ90@85004|Bifidobacteriales	201174|Actinobacteria	LT	Phosphoglycerate mutase family	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	His_Phos_1,NUDIX
IOLKFBCL_02275	216816.GS08_09630	0.0	1462.0	COG0855@1|root,COG0855@2|Bacteria,2GJ0B@201174|Actinobacteria,4CYXH@85004|Bifidobacteriales	201174|Actinobacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
IOLKFBCL_02276	216816.GS08_09625	5.29e-307	838.0	COG1409@1|root,COG1409@2|Bacteria,2HRDZ@201174|Actinobacteria,4CYQR@85004|Bifidobacteriales	201174|Actinobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
IOLKFBCL_02277	216816.GS08_09620	5.17e-179	499.0	COG1414@1|root,COG1414@2|Bacteria,2GKB0@201174|Actinobacteria,4CZ9D@85004|Bifidobacteriales	201174|Actinobacteria	K	Transcriptional regulator, IclR family, C-terminal domain protein	ltbR	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
IOLKFBCL_02278	216816.GS08_09615	0.0	924.0	COG0065@1|root,COG0065@2|Bacteria,2GKT7@201174|Actinobacteria,4CYUC@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
IOLKFBCL_02279	326426.Bbr_1766	2.22e-169	472.0	COG0066@1|root,COG0066@2|Bacteria,2GJ8Z@201174|Actinobacteria,4CZ2F@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
IOLKFBCL_02280	216816.GS08_09605	1.4e-264	725.0	COG0167@1|root,COG0167@2|Bacteria,2GJMN@201174|Actinobacteria,4CZKM@85004|Bifidobacteriales	201174|Actinobacteria	F	Dihydroorotate dehydrogenase	pyr	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
IOLKFBCL_02281	216816.GS08_09600	0.0	879.0	COG0446@1|root,COG0446@2|Bacteria,2H7WY@201174|Actinobacteria,4CZXP@85004|Bifidobacteriales	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	nox	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,Reductase_C
IOLKFBCL_02282	216816.GS08_09595	0.0	883.0	COG0766@1|root,COG0766@2|Bacteria,2GJPW@201174|Actinobacteria,4CZN7@85004|Bifidobacteriales	201174|Actinobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
IOLKFBCL_02283	216816.GS08_09590	4.96e-310	843.0	COG1168@1|root,COG1168@2|Bacteria,2GJFQ@201174|Actinobacteria,4CZFH@85004|Bifidobacteriales	201174|Actinobacteria	E	Aminotransferase, class I II	-	-	4.4.1.8	ko:K00842,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
IOLKFBCL_02284	216816.GS08_09585	2.18e-218	603.0	COG0583@1|root,COG0583@2|Bacteria,2GKT0@201174|Actinobacteria,4D04F@85004|Bifidobacteriales	201174|Actinobacteria	K	LysR substrate binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
IOLKFBCL_02285	326426.Bbr_1756	3.57e-179	508.0	COG2271@1|root,COG2271@2|Bacteria,2HZ9S@201174|Actinobacteria,4CZ4Z@85004|Bifidobacteriales	201174|Actinobacteria	G	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
IOLKFBCL_02286	326426.Bbr_1755	2.83e-154	434.0	COG1309@1|root,COG1309@2|Bacteria,2HZJX@201174|Actinobacteria,4D0QJ@85004|Bifidobacteriales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
IOLKFBCL_02287	77635.BISU_0092	1.73e-238	667.0	COG2723@1|root,COG2723@2|Bacteria,2GJAF@201174|Actinobacteria,4CYPX@85004|Bifidobacteriales	201174|Actinobacteria	G	Glycosyl hydrolase family 1	bglA	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
IOLKFBCL_02288	1680.BADO_0078	0.0	1092.0	COG3250@1|root,COG3250@2|Bacteria,2GM69@201174|Actinobacteria,4D09M@85004|Bifidobacteriales	201174|Actinobacteria	G	beta-mannosidase	-	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2
IOLKFBCL_02289	77635.BISU_0091	2.58e-155	444.0	COG0395@1|root,COG0395@2|Bacteria,2GK1V@201174|Actinobacteria,4CZF7@85004|Bifidobacteriales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026,ko:K10242	ko02010,map02010	M00206,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.23	-	-	BPD_transp_1
IOLKFBCL_02290	401473.BDP_0138	9.88e-171	486.0	COG1175@1|root,COG1175@2|Bacteria,2GMV4@201174|Actinobacteria,4D0C0@85004|Bifidobacteriales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10189,ko:K10241	ko02010,map02010	M00199,M00206	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.23,3.A.1.1.4	-	-	BPD_transp_1
IOLKFBCL_02291	327277.JHAL01000001_gene1434	1.4e-205	581.0	COG1653@1|root,COG1653@2|Bacteria,2GJIP@201174|Actinobacteria,4D068@85004|Bifidobacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10240	ko02010,map02010	M00206	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.23	-	-	SBP_bac_8
IOLKFBCL_02292	356829.BITS_0288	2.46e-138	403.0	COG1609@1|root,COG1609@2|Bacteria,2GMHV@201174|Actinobacteria,4CZ3G@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K03484	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
IOLKFBCL_02293	216816.GS08_09580	0.0	1213.0	COG0018@1|root,COG0018@2|Bacteria,2GKQ3@201174|Actinobacteria,4CZ9J@85004|Bifidobacteriales	201174|Actinobacteria	J	Arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
IOLKFBCL_02294	216816.GS08_09575	0.0	1008.0	COG0019@1|root,COG0019@2|Bacteria,2GKAI@201174|Actinobacteria,4CYRG@85004|Bifidobacteriales	201174|Actinobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
IOLKFBCL_02295	216816.GS08_09570	1.9e-295	808.0	COG0460@1|root,COG0460@2|Bacteria,2GIX9@201174|Actinobacteria,4CZVD@85004|Bifidobacteriales	201174|Actinobacteria	E	Homoserine dehydrogenase	hom	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	1.1.1.3,2.7.2.4	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1294	ACT,Homoserine_dh,NAD_binding_3
IOLKFBCL_02296	216816.GS08_09565	3.57e-261	716.0	COG0083@1|root,COG0083@2|Bacteria,2GKIW@201174|Actinobacteria,4CZN0@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
IOLKFBCL_02297	216816.GS08_09560	0.0	958.0	COG0424@1|root,COG1051@1|root,COG0424@2|Bacteria,COG1051@2|Bacteria,2GNI0@201174|Actinobacteria,4CZXF@85004|Bifidobacteriales	201174|Actinobacteria	DF	Maf-like protein	maf	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf,NUDIX
IOLKFBCL_02298	326426.Bbr_1748	3.14e-11	60.8	COG0454@1|root,COG0454@2|Bacteria,2IC6K@201174|Actinobacteria,4D0SR@85004|Bifidobacteriales	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
IOLKFBCL_02299	1437608.BBIA_1347	2.92e-23	90.1	2B12Y@1|root,30DWC@2|Bacteria,2GWJ2@201174|Actinobacteria,4D1TU@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF1778)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1778
IOLKFBCL_02301	216816.GS08_09545	2.74e-166	469.0	COG1136@1|root,COG1136@2|Bacteria,2GM25@201174|Actinobacteria,4D0FV@85004|Bifidobacteriales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	lolD	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IOLKFBCL_02302	216816.GS08_09540	0.0	881.0	COG0577@1|root,COG0577@2|Bacteria,2GKF3@201174|Actinobacteria,4D03X@85004|Bifidobacteriales	201174|Actinobacteria	V	Efflux ABC transporter, permease protein	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
IOLKFBCL_02303	326426.Bbr_1745	2.48e-231	638.0	COG1609@1|root,COG1609@2|Bacteria,2GJRG@201174|Actinobacteria,4CZI0@85004|Bifidobacteriales	201174|Actinobacteria	K	Bacterial regulatory proteins, lacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
IOLKFBCL_02304	216816.GS08_09530	6.85e-313	852.0	COG4948@1|root,COG4948@2|Bacteria,2GKSK@201174|Actinobacteria,4D0EI@85004|Bifidobacteriales	201174|Actinobacteria	M	Enolase C-terminal domain-like	-	-	4.2.1.68	ko:K18334	ko00051,ko01120,map00051,map01120	-	R03688	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
IOLKFBCL_02305	216816.GS08_09525	2.47e-180	503.0	COG1028@1|root,COG1028@2|Bacteria,2GJGM@201174|Actinobacteria,4CZXI@85004|Bifidobacteriales	201174|Actinobacteria	IQ	KR domain	-	-	1.1.1.100,1.1.1.413	ko:K00059,ko:K18333,ko:K22322	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R08926,R10116,R10120,R11671	RC00029,RC00066,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
IOLKFBCL_02306	1437609.BCAL_2120	1.47e-262	724.0	COG0738@1|root,COG0738@2|Bacteria,2GJ5D@201174|Actinobacteria,4D02K@85004|Bifidobacteriales	201174|Actinobacteria	G	Major Facilitator Superfamily	fucP	-	-	ko:K02429	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
IOLKFBCL_02307	216816.GS08_09515	1.91e-189	525.0	COG3618@1|root,COG3618@2|Bacteria,2HRH9@201174|Actinobacteria,4CZX0@85004|Bifidobacteriales	201174|Actinobacteria	S	Amidohydrolase	-	-	-	ko:K07046	ko00051,ko01120,map00051,map01120	-	R10689	RC00537	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
IOLKFBCL_02308	1437609.BCAL_2123	9.59e-101	292.0	COG4154@1|root,COG4154@2|Bacteria,2INSY@201174|Actinobacteria,4D122@85004|Bifidobacteriales	201174|Actinobacteria	G	RbsD / FucU transport protein family	fucU	-	5.1.3.29	ko:K02431	-	-	R10764	RC00563	ko00000,ko01000	-	-	-	RbsD_FucU
IOLKFBCL_02309	216816.GS08_09505	7.19e-210	582.0	COG0679@1|root,COG0679@2|Bacteria,2GNIA@201174|Actinobacteria,4CZFX@85004|Bifidobacteriales	201174|Actinobacteria	S	Transporter, auxin efflux carrier (AEC) family protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
IOLKFBCL_02310	216816.GS08_09500	6.43e-288	787.0	COG0624@1|root,COG0624@2|Bacteria,2GK09@201174|Actinobacteria,4CZ9K@85004|Bifidobacteriales	201174|Actinobacteria	E	Peptidase dimerisation domain	dapE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
IOLKFBCL_02311	216816.GS08_09495	0.0	1345.0	COG1530@1|root,COG1530@2|Bacteria,2GMM5@201174|Actinobacteria,4CYQT@85004|Bifidobacteriales	201174|Actinobacteria	J	Ribonuclease E/G family	rne	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	IF2_N,RNase_E_G,S1
IOLKFBCL_02312	216816.GS08_09490	4.13e-62	191.0	COG0261@1|root,COG0261@2|Bacteria,2IQ9A@201174|Actinobacteria,4D10B@85004|Bifidobacteriales	201174|Actinobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
IOLKFBCL_02313	216816.GS08_09485	3.99e-53	166.0	COG0211@1|root,COG0211@2|Bacteria,2IQDI@201174|Actinobacteria,4D19N@85004|Bifidobacteriales	201174|Actinobacteria	J	Ribosomal L27 protein	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
IOLKFBCL_02314	216816.GS08_09480	0.0	1083.0	COG0536@1|root,COG0536@2|Bacteria,2GISB@201174|Actinobacteria,4CYWD@85004|Bifidobacteriales	201174|Actinobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	GO:0000287,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0032991,GO:0036211,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0046872,GO:0071704,GO:0071944,GO:1901564,GO:1990904	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
IOLKFBCL_02315	216816.GS08_09475	5.06e-260	714.0	COG0263@1|root,COG0263@2|Bacteria,2GM8U@201174|Actinobacteria,4CZ2B@85004|Bifidobacteriales	201174|Actinobacteria	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
IOLKFBCL_02316	216816.GS08_09470	3.78e-290	792.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,4CZFY@85004|Bifidobacteriales	201174|Actinobacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	aspC	-	2.6.1.1,2.6.1.2,2.6.1.66	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
IOLKFBCL_02318	1437610.BREU_2304	1.95e-41	136.0	COG0690@1|root,COG0690@2|Bacteria,2HZQC@201174|Actinobacteria,4D18K@85004|Bifidobacteriales	201174|Actinobacteria	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
IOLKFBCL_02319	216816.GS08_09455	2.53e-190	531.0	COG0250@1|root,COG0250@2|Bacteria,2GJFW@201174|Actinobacteria,4CYSH@85004|Bifidobacteriales	201174|Actinobacteria	K	Participates in transcription elongation, termination and antitermination	nusG	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusG
IOLKFBCL_02320	216816.GS08_09450	4.11e-95	277.0	COG0080@1|root,COG0080@2|Bacteria,2IFCK@201174|Actinobacteria,4D0PA@85004|Bifidobacteriales	201174|Actinobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
IOLKFBCL_02321	326426.Bbr_1726	1.75e-159	447.0	COG0081@1|root,COG0081@2|Bacteria,2GM51@201174|Actinobacteria,4CZFR@85004|Bifidobacteriales	201174|Actinobacteria	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
## 2075 queries scanned
## Total time (seconds): 4.4375505447387695
## Rate: 467.60 q/s