Select genomic region:
Overview
1.1
2.1
11.1
12.1

### Identified secondary metabolite regions using strictness 'relaxed'

gnlProkkaPBECPFDC_1 (original name was: gnl|Prokka|PBECPFDC_1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | lanthipeptide-class-ii,RiPP-like | 2,864 | 35,569 | microvionin | RiPP | 8%

gnlProkkaPBECPFDC_2 (original name was: gnl|Prokka|PBECPFDC_2)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 2.1 | nucleoside | 19,640 | 40,938 |

gnlProkkaPBECPFDC_12 (original name was: gnl|Prokka|PBECPFDC_12)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 11.1 | NRPS-like | 274,059 | 317,070 | nosiheptide | RiPP:Thiopeptide | 7%

gnlProkkaPBECPFDC_23 (original name was: gnl|Prokka|PBECPFDC_23)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 12.1 | RiPP-like | 32,337 | 42,729 |

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | lanthipeptide-class-ii,RiPP-like | 2,864 | 35,569 | microvionin | RiPP | 8%
Region 2.1 | nucleoside | 19,640 | 40,938 |
Region 11.1 | NRPS-like | 274,059 | 317,070 | nosiheptide | RiPP:Thiopeptide | 7%
Region 12.1 | RiPP-like | 32,337 | 42,729 |

No secondary metabolite regions were found in these records:
  gnlProkkaPBECPFDC_3 (original name was: gnl|Prokka|PBECPFDC_3)
  gnlProkkaPBECPFDC_4 (original name was: gnl|Prokka|PBECPFDC_4)
  gnlProkkaPBECPFDC_5 (original name was: gnl|Prokka|PBECPFDC_5)
  gnlProkkaPBECPFDC_6 (original name was: gnl|Prokka|PBECPFDC_6)
  gnlProkkaPBECPFDC_7 (original name was: gnl|Prokka|PBECPFDC_7)
  gnlProkkaPBECPFDC_8 (original name was: gnl|Prokka|PBECPFDC_8)
  gnlProkkaPBECPFDC_9 (original name was: gnl|Prokka|PBECPFDC_9)
  gnlProkkaPBECPFDC_10 (original name was: gnl|Prokka|PBECPFDC_10)
  gnlProkkaPBECPFDC_25 (original name was: gnl|Prokka|PBECPFDC_25)
  gnlProkkaPBECPFDC_26 (original name was: gnl|Prokka|PBECPFDC_26)
  gnlProkkaPBECPFDC_27 (original name was: gnl|Prokka|PBECPFDC_27)
  gnlProkkaPBECPFDC_28 (original name was: gnl|Prokka|PBECPFDC_28)
  gnlProkkaPBECPFDC_29 (original name was: gnl|Prokka|PBECPFDC_29)
  gnlProkkaPBECPFDC_30 (original name was: gnl|Prokka|PBECPFDC_30)

Compact view
gnlProkkaPBECPFDC_1 - Region 1 - RiPP-like,lanthipeptide-class-ii
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,864 - 35,569 nt. (total: 32,706 nt) Show pHMM detection rules used
Region on contig edge.
lanthipeptide-class-ii: cds(LANC_like and DUF4135)
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
KnownClusterBlast
Lanthipeptides
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Lanthipeptide predictions
Shows the possible core peptides for each biosynthetic enzyme.
Includes CompaRiPPson results for any available databases, with a detailed explanation here.

#### Lanthipeptide(s) for ctg1_13

ctg1_21
Leader:
MVTLKNDNVVGDRGDGAAAA
Core:
V G S A R E L V D G L V S S G R W I P C S S G
Core with dehydrations:
V G Dha A R E L V D G L V Dha Dha G R W I P Cys Dha Dha G

#### antiSMASH-DB 4.0 matches for ctg1_21

100.0% NZ_CABWKH010000001.1 and 1 other:
NZ_CP010411.1 Lanthipeptides: RY67_RS05310_lanthipeptide
Lanthipeptides: BIFLH14_RS13125_lanthipeptide
1
V G S A R E L V D G L V S S G R W I P C S S G
23
V G S A R E L V D G L V S S G R W I P C S S G
1
V G S A R E L V D G L V S S G R W I P C S S G
23
18.8% NZ_CP031746.1: Lanthipeptides: allorf_1813979_1814164_lanthipeptide
11
L V S S G R W I P C S
21
+V R W+P C S
4
V V G C A R W V P C S
14
allorf_004703_004852
Leader:
MACSALVVPAA
Core:
R A G M L V S F F L L L A Y R L T C R R E A N V F G D R R Y F L V L G R A A
Core with dehydrations:
R A G M L V Dha F F L L L A Y R L Dhb Cys R R E A N V F G D R R Y F L V L G R A A

#### antiSMASH-DB 4.0 matches for allorf_004703_004852

100.0% NZ_CABWKH010000001.1: Lanthipeptides: allorf_004703_004852_lanthipeptide
1
R A G M L V S F F L L L A Y R L T C R R E A N V F G D R R Y F L V L G R A A
38
R A G M L V S F F L L L A Y R L T C R R E A N V F G D R R Y F L V L G R A A
1
R A G M L V S F F L L L A Y R L T C R R E A N V F G D R R Y F L V L G R A A
38
21.1% NZ_SGWQ01000010.1: Lassopeptides: EV193_RS25540_lassopeptide
22
A N V F G D R R Y F L V L G R A A
38
+G D R F L G R A
1
C T P W G D C R D F L G C G R A P
17
16.7% NZ_CP077072.1: Lanthipeptides: allorf_2556081_2556245_lanthipeptide
24
V F G D R R Y F L V L G R A A
38
V G+R+ +V G R A
8
V S G E R K L S V V P G R A G
22
with 1 more sequence matches
15.1% NZ_CP023466.1: Lanthipeptides: allorf_0909586_0909777_lanthipeptide
1
R A G M L V S F F L L L
12
R A G+ S F L L L
40
R A G V A C S I F L L L
51
allorf_011277_011396
Leader:
MRPAFRVGEPGA
Core:
I T T T S R P T P A T K S S S H C S R A R I C L Q P Q
Core with dehydrations:
I Dhb Dhb Dhb Dha R P Dhb P A Dhb K Dha Dha Dha H Cys Dha R A R I Cys L Q P Q

#### MIBiG 3.1 matches for allorf_011277_011396

18.5% BGC0002110 (QKV49894.1): Lanthipeptide: birimositide
9
P A T K S S S H C
17
P T K +S C
18
P T T K C T S K C
26
13.5% BGC0001229 (SBI_06989): Lanthipeptide: SBI-06990 A1 or SBI-06989 A2
9
P A T K S S S H C
17
P T K +S C
29
P T T K C T S R C
37

#### antiSMASH-DB 4.0 matches for allorf_011277_011396

100.0% NZ_CABWKH010000001.1: Lanthipeptides: allorf_011277_011396_lanthipeptide
1
I T T T S R P T P A T K S S S H C S R A R I C L Q P Q
27
I T T T S R P T P A T K S S S H C S R A R I C L Q P Q
1
I T T T S R P T P A T K S S S H C S R A R I C L Q P Q
27
25.9% NC_018750.1 and 1 other:
NZ_CP029196.1 Lanthipeptides: allorf_0617083_0617295_lanthipeptide
Lanthipeptides: allorf_0633794_0634006_lanthipeptide
2
T T T S R P T P A T K S S S H C S R A
20
R P T P S C R+
1
D D A D R P T P G R N E G S W C P R S
19
14.0% NZ_LT607411.1: Lanthipeptides: allorf_4738370_4738597_lanthipeptide
6
R P T P A T K S S S H C S
18
R P T T+S H C
10
R P T T V T R S R H H C G
22
allorf_021961_022158
Leader:
MHGPIRVIRRDGVTLGG
Core:
P Q H A Q H E Q R G R G G K P V D Q H A A R F P Q F Q R S I A H I S Y P R L R S A Y I A C V S V
Core with dehydrations:
P Q H A Q H E Q R G R G G K P V D Q H A A R F P Q F Q R Dha I A H I Dha Y P R L R Dha A Y I A Cys V Dha V

#### antiSMASH-DB 4.0 matches for allorf_021961_022158

100.0% NZ_CABWKH010000001.1 and 1 other:
NZ_CP010411.1 Lanthipeptides: allorf_1259774_1259971_lanthipeptide
Lanthipeptides: allorf_021961_022158_lanthipeptide
1
P Q H A Q H E Q R G R G G K P V D Q H A A R F P Q F Q R S I A H I S Y P R L R S A Y I A C V S V
48
P Q H A Q H E Q R G R G G K P V D Q H A A R F P Q F Q R S I A H I S Y P R L R S A Y I A C V S V
1
P Q H A Q H E Q R G R G G K P V D Q H A A R F P Q F Q R S I A H I S Y P R L R S A Y I A C V S V
48
17.9% NZ_AP018172.1: Lanthipeptides: allorf_1980623_1980829_lanthipeptide
7
E Q R G R G G K P V D Q H A A R F P Q F Q R S I A H I S Y P R L R S A
41
+Q G G G P +Q F P + ++ P R +
3
K Q C G L G G L P H E Q L P K G F P G L K E A V R C G G S P R C S N C
37
14.6% NZ_JAAZQN010000004.1: Lassopeptides: FHW94_RS14590_lassopeptide
10
G R G G K P V D Q H A A R F
23
G G G P V D++ +F
1
G A G G I P V D E N L G Q F
14
with 1 more sequence matches
13.6% NZ_CP025394.1 and 1 other:
NZ_CP025394.1 Lanthipeptides: allorf_1695292_1695519_lanthipeptide
Lanthipeptides: allorf_1695292_1695519_lanthipeptide
5
Q H E Q R G R G G K P V D Q H A A R F P Q F Q R S I A H I S Y P
36
+ + R G G P Q A R P + ++ P
29
E G D G R G T A G T P T R Q S A V R H P P Q P P N C G P L A A P
60
allorf_022137_022208
Leader:
MPPARTAAASGM
Core:
S T I G V C M A Q Y E
Core with dehydrations:
Dha Dhb I G V Cys M A Q Y E

#### antiSMASH-DB 4.0 matches for allorf_022137_022208

100.0% NZ_CABWKH010000001.1 and 1 other:
NZ_CP010411.1 Lanthipeptides: allorf_1259724_1259795_lanthipeptide
Lanthipeptides: allorf_022137_022208_lanthipeptide
1
S T I G V C M A Q Y E
11
S T I G V C M A Q Y E
1
S T I G V C M A Q Y E
11
allorf_022146_022298
Leader:
MGHAHTNRAHAAGG
Core:
G R P C R W H R A G L A V R E T R M G D G R S A C P R V A A G S C R R G
Core with dehydrations:
G R P Cys R W H R A G L A V R E Dhb R M G D G R Dha A Cys P R V A A G Dha Cys R R G

#### antiSMASH-DB 4.0 matches for allorf_022146_022298

100.0% NZ_CABWKH010000001.1 and 1 other:
NZ_CP010411.1 Lanthipeptides: allorf_1259634_1259786_lanthipeptide
Lanthipeptides: allorf_022146_022298_lanthipeptide
1
G R P C R W H R A G L A V R E T R M G D G R S A C P R V A A G S C R R G
36
G R P C R W H R A G L A V R E T R M G D G R S A C P R V A A G S C R R G
1
G R P C R W H R A G L A V R E T R M G D G R S A C P R V A A G S C R R G
36
30.6% NZ_RYYV01000004.1: Lanthipeptides: allorf_104369_104572_lanthipeptide
6
W H R A G L A V R E T R M G D G R S A C P R V A A G S C
33
W+R L R T G G R+ C R +C
3
W Y R N T L R S R S T-A G K G R N T C L R R Q V H A C
29
26.3% NZ_CP119804.1: Lanthipeptides: P2T57_RS09790_lanthipeptide
1
G R P C R W H R A G L A V R E T R M G D G R S A C P R
27
G C W A G R E G D C
3
G D D C S W C S A G T L A R E E F K G D D A V V C D E
29
with 2 more sequence matches
25.0% NZ_JALBFU010000008.1: Lanthipeptides: allorf_86167_86340_lanthipeptide
4
C R W H R A G L A V R E T R M G D G
21
C R R G L A+ T R+ G
4
C R P A R H G L A L P P T R I A S G
21
16.7% NZ_CP077072.1: Lanthipeptides: allorf_2556044_2556175_lanthipeptide
3
P C R W H R A G
10
P C W R A G
2
P C S W S R A G
9
allorf_024255_024410
Leader:
MGKLPPHGIFTASWMYGS
Core:
R R P N C L V P P I T M F G R L R W S G P G R R F G M T F L P C R
Core with dehydrations:
R R P N Cys L V P P I Dhb M F G R L R W Dha G P G R R F G M Dhb F L P Cys R

#### antiSMASH-DB 4.0 matches for allorf_024255_024410

100.0% NZ_CABWKH010000001.1: Lanthipeptides: allorf_024255_024410_lanthipeptide
1
R R P N C L V P P I T M F G R L R W S G P G R R F G M T F L P C R
33
R R P N C L V P P I T M F G R L R W S G P G R R F G M T F L P C R
1
R R P N C L V P P I T M F G R L R W S G P G R R F G M T F L P C R
33
18.2% NZ_FMUR01000003.1: Lanthipeptides: allorf_188176_188259_lanthipeptide
2
R P N C L V P P I T M F G R L
16
R +C++P I G R+
2
R I S C I L P L I I F M G R I
16
15.2% NZ_CP033875.1: Lassopeptides: allorf_0475837_0476004_lassopeptide
13
F G R L R W S G P G R R F G M
27
F G++ P R+G+
5
F G Q I E A E D P S D R Y G V
19
allorf_025661_025900
Leader:
MHTSFSSLKDHRLTYFRTTWHHFRAISGLQGA
Core:
D L R L S G H L P P F Q G A L H P R K R K Y K R L C F N A I K P F W G R V Y F G N S P L K R R
Core with dehydrations:
D L R L Dha G H L P P F Q G A L H P R K R K Y K R L Cys F N A I K P F W G R V Y F G N Dha P L K R R

#### antiSMASH-DB 4.0 matches for allorf_025661_025900

19.1% NZ_CP017316.1: Lanthipeptides: allorf_6268660_6268842_lanthipeptide
3
R L S G H L P P F Q G A L H P R K R K Y K R L
25
R +G H P Q G H R+ + R
7
R G A G H A P-C Q G V C H Q R E E R A D R A
28
17.0% NZ_CAJHJS010000009.1: Lanthipeptides: allorf_72861_73019_lanthipeptide
17
P R K R K Y K R L C F N A I K P F W G R V Y F G N
41
+ K++ C N I K V F N
1
D K T A K H R N F C V N L I K S E L F L V T F S N
25
17.0% NZ_CP069396.1: Lanthipeptides: allorf_00880550_00880726_lanthipeptide
25
L C F N A I K P F W G R V Y F G N S
42
+C F N+ + G R + G N S
9
V C F N S H R A G N G R A H E G N S
26
with 2 more sequence matches
14.9% NZ_KV815277.1: Lanthipeptides: allorf_240790_240948_lanthipeptide
26
C F N A I K P F W G R V Y F G N S P L K
45
C N++ W G N L K
11
C L N S V I K I W G D T I N F N L S L K
30
12.8% NZ_JAHXMW010000012.1 and 1 other:
NZ_JAHXMW010000012.1 Lanthipeptides: allorf_053850_054050_lanthipeptide
Lanthipeptides: allorf_053850_054050_lanthipeptide
34
W G R V Y F G N S P L K
45
W + Y G N S L
6
W N K A Y V G N S L L N
17

#### Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine
Lanthipeptides
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists the number of lanthionine bridges, possible molecular weights, and the scores for cleavage site prediction and RODEO.

ctg1_21 - Class II
  Cleavage pHMM score: -6.00
  RODEO score: 0
  Monoisotopic mass: 2241.2 Da
  Molecular weight: 2242.5 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    2260.5 Da N = 1
    2278.5 Da N = 2
    2296.6 Da N = 3
    2314.6 Da N = 4
allorf_004703_004852 - Class II
  Cleavage pHMM score: -5.60
  RODEO score: 0
  Monoisotopic mass: 4384.4 Da
  Molecular weight: 4387.2 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    4405.2 Da N = 1
allorf_011277_011396 - Class II
  Cleavage pHMM score: -3.50
  RODEO score: 0
  Monoisotopic mass: 2746.5 Da
  Molecular weight: 2748.1 Da
  Number of bridges: 2
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    2766.1 Da N = 1
    2784.1 Da N = 2
    2802.2 Da N = 3
    2820.2 Da N = 4
    2838.2 Da N = 5
    2856.2 Da N = 6
    2874.2 Da N = 7
    2892.3 Da N = 8
allorf_021961_022158 - Class II
  Cleavage pHMM score: -3.70
  RODEO score: 0
  Monoisotopic mass: 5377.8 Da
  Molecular weight: 5381.0 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    5399.0 Da N = 1
    5417.0 Da N = 2
    5435.1 Da N = 3
allorf_022137_022208 - Class II
  Cleavage pHMM score: -7.30
  RODEO score: 0
  Monoisotopic mass: 1164.5 Da
  Molecular weight: 1165.3 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    1183.3 Da N = 1
allorf_022146_022298 - Class II
  Cleavage pHMM score: -4.40
  RODEO score: 0
  Monoisotopic mass: 3853.9 Da
  Molecular weight: 3856.4 Da
  Number of bridges: 3
allorf_024255_024410 - Class II
  Cleavage pHMM score: -6.90
  RODEO score: 0
  Monoisotopic mass: 3820.0 Da
  Molecular weight: 3822.6 Da
  Number of bridges: 2
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3840.6 Da N = 1
allorf_025661_025900 - Class II
  Cleavage pHMM score: -6.80
  RODEO score: 0
  Monoisotopic mass: 5584.1 Da
  Molecular weight: 5587.6 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    5605.6 Da N = 1

gnlProkkaPBECPFDC_2 - Region 1 - nucleoside
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 19,640 - 40,938 nt. (total: 21,299 nt) Show pHMM detection rules used
nucleoside: (LipM or LipV or LipU or ToyB or TunD or pur6 or pur10 or nikJ or nikO or truD)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
KnownClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

gnlProkkaPBECPFDC_12 - Region 1 - NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 274,059 - 317,070 nt. (total: 43,012 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
NRPS/PKS domains
KnownClusterBlast
NRPS/PKS modules
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A domain glossary is available here, and an explanation of the visualisation is available here.
Selected features only
Show module domains
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Module view
Shows module structures for each candidate cluster in NRPS and PKS regions.
Genes are shown in predicted order, and are only present when containing at least one complete module.
A domain glossary is available here, and an explanation of the visualisation is available here.
Legend
NRPS/PKS products
NRPS/PKS substrates
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 274058 - 317070:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (X)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS substrate predictions
Shows the predicted substrates for each adenylation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg11_266: X
  AMP-binding (14..381): X
  nrpys: (unknown)
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
    Large clusters prediction:
      Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
    Small clusters prediction:
      Tiny, hydrophilic, transition to aliphatic (Gly, Ala)
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DFFTIGIIYK
    Nearest Stachelhaus code(s):
      Ile DFWNIGIIYK (56% 8Å match)
    Stachelhaus code match:
      80% (moderate)

gnlProkkaPBECPFDC_23 - Region 1 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 32,337 - 42,729 nt. (total: 10,393 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
KnownClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.