LOCUS       gnlProkkaKPLPNPMH_1    16283 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KPLPNPMH_1.
ACCESSION   gnlProkkaKPLPNPMH_1
VERSION     gnlProkkaKPLPNPMH_1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 23:17:26
            Original ID  :: gnl|Prokka|KPLPNPMH_1
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 242261
            Orig. end    :: 258544
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16283
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:11283]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..11283
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..16283
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..16283
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="2"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             98..304
                     /locus_tag="ctg1_229"
                     /transl_table=11
                     /translation="MRERGQVWSYSEVKRESQLANYNTDGRYLSETTNFELYNFVREYK
                     TSDEIRRIWNPKKDESVIHDKDN"
     CDS             492..2249
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 390.1; E-value:
                     3e-118)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_230"
                     /transl_table=11
                     /translation="MFFKESIIAKLWWFFKLEKRRYIVGILALSLVSVLNLLPPMVMGR
                     VIDAITSGKLTNQILLLNLVYLLLAALGMYYLRYVWRMYILATSYRLGQIMRSRLFEHF
                     TKMSPSFYQKYRTGDLMAHATNDINSLTRLAGGGVMSAVDASITALVTLITMFFSISWQ
                     MTLVAVLPLPFMAFATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQEA
                     ELQSFQETNKMTFEKNMHTMKYDSLFDPLVLLFVGSSYVLTLLVGAFMIQAGQITVGNL
                     VTFITYLDMLVWPLMAIGFLFNITQRGNVSYQRIETLLEQESDVQDPAYPLPSIKNGRL
                     DFAIDRFAFEDEDTLRDIHFTLDKGQTLGLVGPTGSGKTALVKLLLREHDVNQGAIYLN
                     GHDIRDYRLSDLRSLIGYVPQDQFLFASSILDNVRFGNPDFSIDKVEEATKLAQVYDDI
                     KDMPEGFETIIGEKGVSLSGGQKQRLAMSRAMILNPEILILDDSLSAVDAKTEHAIIDN
                     LKHTRKNKTTIITAHRLSAVVHADLILVMQDGRIIERGRHDDLLAQGGWYAKTYGSQQL
                     EMEGGEAHA"
     CDS             2242..3987
                     /gene_functions="resistance (resist) ABC_efflux (Score:
                     283.7; E-value: 1.8e-86)"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 310.5; E-value:
                     3.9e-94)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_231"
                     /transl_table=11
                     /translation="MPNQNQWSVFKRLLTYLKPYKFLTFLALTFLLSTTVIKSIIPLVA
                     SYFIDHYLHDMNQAASMILIGYYGLYLLQTLVQYLGNLFFARVSYSIVRDIRRDAFANM
                     EKLGMSYFDKTPAGSIVSRLTNDTETISEMFSGILSSFISAIFIFVTTLYTMMILDIRL
                     TGLIVLFLPLIVLLVNLYRKKSVVIIEKTRALLSDINAKLSESIEGIHIIQAFNQEKRL
                     KKEFDAINEEHLIYASRSISLDSLFLRPAMSLLKLLAYAVLMAYFGYRGIYLGITAGTM
                     YAFIQYVNRLFDPLIEVTQNFSTLQTSMVSAGRVFALIDERTYEPEQRDTAAKVTEGNI
                     RFENVSFSYDGKHQILDNISFSVNKGETIAFVGSTGSGKSYIINVLMRFYEFQSGRVLL
                     DGVDIRDYSQAELRKNIGLVLQDPFLYHGTIKSNIAMYQDLTDEEIKAAAEFVDANHFI
                     DKLPEGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANIDSETEAIVQNS
                     LAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIEHGSHEELLVLGGTYHKMYSLQAG
                     TMEGE"
     CDS             5001..7154
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 305.7; E-value:
                     1.1e-92)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_232"
                     /sec_met_domain="Peptidase_C39 (E-value: 7.2e-43, bitscore:
                     142.4, seeds: 36, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR01193 (E-value: 0.0, bitscore: 1101.1,
                     seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFRFRRTFVPQIDMRNCGVAALALVAKYYGSDYSLAHLRELAKTN
                     KEGTTALGLVEAAKKIGFETRAIKAEMSLFEMEDVPYPFIAHVNKDGKLQHYYVIYKST
                     KDYLIIGDPDPSVKVTKMTKERFEKEWTGVTLFMGPEPSYKPHKDKKNGLWDFLPLIFK
                     QRSLIANIVFASLLVTLINILGSYYLQGILDEYVPNQMKSTLGIISIGLVVTYVLQQMM
                     TFARDYLLTILSQRLTIDVILSYIRHIFELPMSFFATRRTGEVISRFSDANSIIDALAS
                     TILSLFLDFSIVIIVGGVLLIQNSNLFKLVLCSVPIYTLIVFAFMKPFELMNHDVMQSN
                     AMVNSAIIEDINGIETIKSLTSEEVCYQKIDGEFVDYLDNSFRLSKLSILQTSLKQGAQ
                     LILNVLILWTGAQLVMGNTISIGQLITFNMLLSYFTNPLENIINLQTKLQSAKVANTRL
                     NEVYLIESEFGQSDDTYQEGIADGDITVTDLSYKYGFGRDTLTDVSLTIRQGEKISFVG
                     VSGSGKTTLAKMLVNFYQPYKGHIDFNGQNISRIDKKTLRQHINYLPQQSYIFSGSVLE
                     NLTLGAARGITQADILKACEIAEIRQDIENMPMGFQTELSDGAGLSGGQKQRIALARAL
                     LTKSPVLILDEATSGLDVLTEKQVIDNLLALKDKTIIFVAHRLSIAERTDRIVVIDQGR
                     VVETGSHQDLMSYPGFYYQLFRK"
     CDS             7170..7505
                     /locus_tag="ctg1_233"
                     /transl_table=11
                     /translation="MNPQLFKSTEFYHRRYHNMSTVLITPLILLVIFLFLFAFFAKKEV
                     TVTSRGSIEPTKVIAVIQSTSDNTIIDNQLVANKVVKKGDTLVQYSETMEASQKEGLQK
                     QLELLKR"
     CDS             7633..8538
                     /locus_tag="ctg1_234"
                     /transl_table=11
                     /translation="MGVAKTNTEVNNQAAIASNTGSAIDNQISQLQTQVSEYEALSQAI
                     TNHETTLPEGNPHQATLNAYNSQYATTPDASVTDQYLSQVNTNISSLNASIGNLEIQKA
                     GTGTAVTYDNSDSTKKEALKNQFLQNAGQQLSSVETQITDTESKINQADVLLTNTLIQS
                     PEDGILHLSQADKKATMAATGTELAQLYPDMTQTQEVAITYYVNSDYVPKLQKGQSVRL
                     TLDKVGNHGTTIIGKLESIDNSATETERGNVFRVTARASISEKEAQNLRYGLEGRVTSV
                     IDQKTYFNYFKDKLLNLQDQ"
     CDS             8553..8714
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_235"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 3e-07, bitscore:
                     27.5, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANNTINNFETLDNHALEQVVGGSGWMDYINGFLKGFGGQRTLPT
                     KDYNIPQV"
     CDS             complement(8732..10075)
                     /locus_tag="ctg1_236"
                     /transl_table=11
                     /translation="MMLTTLWLLFLTLLSAGLEIILFLYLMGQKIRLRYFFLLLIFNLA
                     FNFIYNHSSWFIIKFWGEDIYYLLLSFLLSTKTKKPLKIKIFNGLFPDILNNLSLRLIT
                     FFIFPFFNISITDYKSSLLISIPSSIAPLCLSFLFIKLFKESFTILQKQKSNSPIQHII
                     IVANFFMFGYTLLLQSLMYLENTTHSSTLELRKLCVVISLVLFFIMIVFLERNIREMIQ
                     GQLDFQKNLQLENLYTYNKHIECLYNSVRSFRHDYSNLLVTLRLGIDKDDMDIVKEVYD
                     SVLQESDKRLNTRNFDLARLVNIQDNTLKSLLSAKVLQAEEEGIEAQISIPEPIHLIGM
                     EILDFIIVTSIFLDNAIEGAIQTQNHKITISFWEDHRSQLLSISNTISEEQTETKTIFE
                     RGVSNKGRERGIGLANVTEILDNYINVNLETQSNNFSFTQQLTITKKA"
     CDS             complement(10072..10803)
                     /locus_tag="ctg1_237"
                     /transl_table=11
                     /translation="MKIYLLEDNSIQMGRLEEAVAHELKSFGKDLSCVQSFDKPDQLLS
                     AITSNTSDQIFFLDIEIKGEDKKGLDIAKIVRQNNPYAIIAFVTTHIEFMPQAFGVTAY
                     KYINKTLDEASFRKEIGETIAQVFPINATTTDEFFLYKTESQLINLPMDQILYLSTSDI
                     KHHVHLQTIHTLMDIRANLADFKKIHKKLYPCHRSYIVNTDMIISVNKTNYEATLINGQ
                     VLPVSRMKIGKIAQIVEERGR"
     CDS             11053..11283
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_238"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 3.2e-17,
                     bitscore: 59.5, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATQTIENFNTLDLETLASVEGGGCSWGGFAKQGVATGVGNGLRL
                     GIKTRTWQGAVAGAAGGAIVGGVGYGATCWW"
     CDS             11290..11415
                     /locus_tag="ctg1_239"
                     /transl_table=11
                     /translation="MFDLKSYILGMVSMAVMSFLDKPIMSFLEKHKATNSVKKKS"
     CDS             11773..11940
                     /locus_tag="ctg1_240"
                     /transl_table=11
                     /translation="MFKNSKPYLLATILIVMGLANLFRSLDAVHHTINLLGLTVLLYSL
                     LFKKWVQFQK"
     CDS             12270..12671
                     /locus_tag="ctg1_241"
                     /transl_table=11
                     /translation="MKLKNISSSVLRSFRTITAALAVFLISISLSLYKSKISPGTWLAV
                     GALAFVVIFVNGLLYRMLKKRPDSVNLLTIRQSFIVFPVITFLVLSVEFYTLLTFSDTT
                     DRIVLAVLMLLLILCDFLSYLQVKKYFKQ"
     CDS             12922..13062
                     /locus_tag="ctg1_242"
                     /transl_table=11
                     /translation="MATQTIENLTPLTSKHLLVLKEVDVVGEAQVERLFKELSEERLEV
                     M"
     CDS             complement(13309..14178)
                     /gene_functions="other (smcogs) SMCOG1026:transposase
                     (Score: 247.8; E-value: 1.9e-75)"
                     /gene_kind="other"
                     /locus_tag="ctg1_243"
                     /transl_table=11
                     /translation="METFQAIKEYADEYEEVSISHLCHILKVSRSGYYKWLQHQETTSE
                     QENLGLMDIIKKLHSQHNGILGYRRMTLFVNRKLETNYNKKRIRRLMHILGLRSIIRRA
                     KGYCTKTSFVNVEDNILNRNFTATAPNQKWCTDVTFLKYGFSCKAYLSAIKDLYDGSIV
                     AYVVGQFNDNELVLETLRKAQKANPNATPLIHSDRGSQYTSKDYYRLTTQYQMTRSMSR
                     VGKCIDNAPIESFFGHFKTECYDLKKYKTFEELVSDIDAYIYFYNHQRFQERNNGLAPL
                     EMRNKAVA"
     CDS             complement(14193..14879)
                     /gene_functions="other (smcogs) SMCOG1164:transposase
                     IS3/IS911 family protein (Score: 25.1; E-value: 2.3e-07)"
                     /gene_kind="other"
                     /locus_tag="ctg1_244"
                     /transl_table=11
                     /translation="MSKRSPKSVSEKLEIVLLHLEEGKSLSWLTRNQGISKDTLSNWVR
                     KYKEAGVDGLEESRQWKKYSKELKEQAVSDYLNGLGSLKDLTKKYGISDPYVLRSWIKS
                     YTSGKELKATSKGMRRMKQGRKTTFEERIEIVNFTLAHEKDYQGAVEKYGVSYQQIYSW
                     VRKFEKDGSNGLLDRRGKGLTSKPNLTPEEELRLKIKQQEERIKYLEMENGLLKKLEEI
                     KRRNRR"
     CDS             15073..16002
                     /locus_tag="ctg1_245"
                     /transl_table=11
                     /translation="MKKRTLTLWMMSSALLLNLSVGTALADEVVETGADNSPKVEATES
                     TPVEQPSDSQEQSLPEDKEAPAATESVTLAESEEETAKNDIPAVSREEYDANVADLPKI
                     SLDDVRNAFTEDGQAHTIYFGRGTCYYCRQFSPELKVLNQLMDGRLEYYDIDREDFDRN
                     YVFGEIGIPGTPTLLYLENGQLLSGWVGGGPAQTVYDHLASSSPRFMTLNQEQTTISEP
                     QTKTVRPTRVTEESTKEKSLPTVQPQPMSTVQKELNAQTGQMAPMTDKVADTKEFPKTN
                     DGEQSLVSFVGALAILASLMLALRYYIK"
ORIGIN
        1 acacttaatg tgacagtagt cactgtattg acactatgag caacaatgac agcggttaaa
       61 gcagatactt atcaaaagtg gccgtgatgc cgatattatg cgagaaagag gtcaggtttg
      121 gagctattct gaggttaaaa gagagtctca attagctaac tacaacactg atggtcgcta
      181 tctcagtgag acaactaact tcgaattgta caattttgtc agagagtata agacatctga
      241 tgaaatcaga cgtatttgga accctaagaa ggacgaatca gttatccacg ataaggataa
      301 ctgattctat tgatgatggg cacaaggtct ataattttga ctcctttgct tatcaattgc
      361 cagagtctac tgattttgga aaattgactt atattggtca ctttcagtta gaagatggta
      421 caatttatcg ctattggaaa taactttcat tagacttata atcatccttt tgtagggata
      481 gggggaataa cttgtttttt aaagaatcaa tcattgcaaa actttggtgg tttttcaagt
      541 tagaaaaacg ccgttatatt gtcgggatat tggcactgag tttggtttcg gttctcaatc
      601 tgcttcctcc tatggttatg ggtcgggtca ttgatgctat cacatcggga aaattgacca
      661 atcagatctt gcttttgaat ctcgtttatt tgcttttggc ggctttagga atgtactatt
      721 tgcgctatgt ttggcggatg tatatcttgg caacgtctta tcgcttggga cagattatgc
      781 gttcgcggct ttttgagcat tttaccaaga tgtcgccttc tttttaccaa aagtaccgaa
      841 ctggtgatct catggcccat gccaccaatg atatcaactc tctaacccgt ttggctggtg
      901 ggggtgtcat gtcagccgtg gatgcgtcta tcacagcctt ggtgacttta atcaccatgt
      961 tcttcagcat ttcctggcag atgaccctgg tggcagtctt acctctacct ttcatggctt
     1021 ttgcgactag tcgtttggga cgtaagaccc acaaagcttt tggagaatcc caggcagctt
     1081 tttctgaact taataataag gtacaagaat cggtgtcagg tatcaaggta accaagtctt
     1141 ttggctatca ggaggctgag ctccagtcct tccaagagac caataagatg acttttgaaa
     1201 agaatatgca taccatgaag tatgacagcc tttttgatcc tttggtcttg ctctttgttg
     1261 gctcatctta tgttttgacc ctccttgtcg gggcctttat gattcaggcc ggtcagataa
     1321 cggtcggaaa tttggtaacc tttattacct atttggacat gctggtttgg cccctaatgg
     1381 ccattggctt cctctttaat atcacgcaga ggggaaatgt gtcctaccaa cgtatcgaga
     1441 ctcttttaga gcaggaatca gatgttcaag atcctgctta tcctcttcca agcattaaaa
     1501 atggtcgttt agactttgcg attgaccgct ttgcttttga ggatgaggat actttgcgag
     1561 atattcattt caccttggac aaggggcaaa cccttggttt ggttggaccg actggctcag
     1621 gaaagacggc tcttgtcaag ttgctcttgc gggagcacga tgtcaatcaa ggagctatct
     1681 atttgaatgg acatgacatc cgagactatc gcctatcaga cttgcgtagc ttgattggtt
     1741 atgttcctca agaccagttt ctctttgcta gttctatttt agacaatgtc cgctttggta
     1801 atccagattt ctccattgat aaggtggaag aagcgactaa gttagctcaa gtttatgatg
     1861 atatcaagga tatgcctgaa ggctttgaaa caatcattgg tgaaaagggt gtcagcctat
     1921 caggtggtca aaaacaacgt ctggctatga gccgggccat gattttgaat ccagaaattt
     1981 tgattttgga tgactcctta tctgcggttg atgctaagac agaacatgcc attattgata
     2041 atcttaagca tactcgcaag aacaaaacaa ctattattac cgcccaccgt ctcagtgcgg
     2101 tggtgcacgc tgacctcatc ctggtcatgc aagatggtcg tatcattgaa cgtgggcgtc
     2161 atgacgactt actagctcaa ggtggttggt atgccaagac ctatgggtct caacagttag
     2221 aaatggaagg aggagaagct catgcctaat caaaaccaat ggtctgtgtt taagcgtctc
     2281 ttgacctatc tcaagcctta caagttcttg acctttctag ctttgacctt cctcttgtcc
     2341 acaacggtta tcaagagtat cattcccttg gtggcctctt attttattga tcactatctt
     2401 catgatatga atcaggcggc aagtatgatt ctgattggct actatggtct ctacctcttg
     2461 cagacactag tccagtatct gggaaatctc ttctttgcgc gtgtgtccta tagcattgtc
     2521 agagatattc gtcgagatgc ctttgccaat atggaaaaac tgggtatgtc ttactttgac
     2581 aagaccccag caggttccat cgtttcccgc ttgaccaatg atactgagac cattagcgag
     2641 atgttctcag gaattctgtc tagttttatt tcggctatct ttatctttgt taccaccctt
     2701 tacaccatga tgatcttgga cattcgtctg accgggctta ttgtcctctt tcttcctctg
     2761 attgtccttt tggttaacct ttatcgcaaa aaatcagtgg tcatcattga aaagaccaga
     2821 gccttgcttt cagatataaa tgccaaactg tcagagagta tcgaagggat tcacatcatt
     2881 caggccttta accaggagaa gcgtcttaaa aaagagtttg atgccattaa tgaggaacac
     2941 ctgatttatg ccagccgttc tatatcactg gattctctct ttctacgccc agccatgagt
     3001 ctactgaagc tcctggctta tgctgttctc atggcctatt ttggctaccg aggtatctat
     3061 ctgggtatca cagcaggtac catgtatgcc tttatccagt atgttaatcg cctctttgat
     3121 cccttgattg aagtgacaca aaacttctcg actctacaaa cctctatggt ctcagcaggt
     3181 cgggtctttg ccttgattga cgagcgtacc tatgagcctg aacagagaga cacagctgcc
     3241 aaggttactg aggggaatat tcgctttgag aatgtctcct tctcctatga tggcaagcac
     3301 cagattttgg ataatatttc cttctctgtc aataaaggtg aaaccatcgc ctttgtggga
     3361 tctacaggct ctggaaaatc ctatattatc aacgtgctca tgcgattcta tgagttccaa
     3421 tcaggacgag ttctcctaga cggtgtggat attcgtgatt atagtcaggc agagctgcgc
     3481 aagaatattg gtcttgtcct tcaggacccc ttcctctatc atggcacaat caaatccaat
     3541 attgccatgt atcaagattt aactgatgaa gagattaaag ctgctgctga gtttgtcgat
     3601 gccaatcact ttattgataa acttcctgaa ggctatgatt ccccagtttc cgaacgtggt
     3661 tcaagtttct caaccggtca acgccagctt ctagcctttg ctagaaccgt tgctagccag
     3721 cctaaaatct tgattttgga tgaagcgaca gccaatattg attcggagac agaggctatt
     3781 gttcaaaact ctcttgcaaa aatgcgtcaa ggccgtacaa ccattgccat tgcccaccgc
     3841 ctatcaacaa tccaagatgc taactgcatc tatgtcttag acaagggccg catcattgaa
     3901 cacggtagcc acgaagagct cctagtcctc ggcggcacct atcacaagat gtacagccta
     3961 caagcaggca ccatggaagg agagtaagct aatctagacc atagcttcta tattcgaaaa
     4021 gatttcttaa aaatcaaaat cgagtagtga catttatgtc actacttttt tgttggctac
     4081 caccctataa taaaatcata gcttgagaga aaaagctaaa aataatttag gaggttgtta
     4141 gaatgacaag gcaaacaaat aatacatttg aaacactcga tctcgaggta cttgcaaacg
     4201 ttgaggtagt gtaaaataag ttgtgtaaac acaaaaagga ataaatccgt tatagtagag
     4261 ttgcaaaaca ttactagaaa gagatttatt cctatgactc agtttaccac agaactactt
     4321 aacttcggct ctataatttc tgtagtggga aaaaccactg tagagattat agagcttttt
     4381 gagatggtgc cacctcaagg ttgagtaaat caaaagatag aaggcacaat tactcaaggt
     4441 ggaaataagg tgggcattaa ggaagggaac ccctctagtg acgctaaaaa tagcattgac
     4501 agtgataaca aatacactta caaagctaag gaaaattaaa ccgataattg agtaatcgaa
     4561 tctcaagagg ctgatttagc cttttttgat aggatttttt gagatatgga ttgacgtttt
     4621 tcataatgtt atcccttttc ggaataaaaa taatcaaatt atgacatcat acgatagaga
     4681 taggctccga ggctatcagc agtcatggtt tcctttggaa ataccagggc tggcacagta
     4741 ataatggtta gatcaaatac gtatgcttgt aggactattt tagaatgttt ccttctaata
     4801 actattgtat aactttgaaa tcgatttcaa tgaacttgtc ctaaatgacc ccaaatacgg
     4861 cttaagtggt aatagtggag atgactttaa gatttttctt accgtttggg acgtatggca
     4921 actttttggg acgctggctc tttttatcct gaaaatatga catactaatc atatgataat
     4981 ttgtgatgaa agggtttggt atgtttcgtt ttcgtaggac ttttgtccct caaatagaca
     5041 tgaggaattg tggagttgct gccttggcat tagtggccaa gtactatggt tcagattatt
     5101 cattagcaca tctgcgtgag ttggcgaaga ccaataaaga agggacaact gccttaggtc
     5161 ttgtagaggc tgctaaaaaa attggctttg aaacgagagc tataaaggct gaaatgtcgc
     5221 tctttgagat ggaagatgtt ccttatcctt ttattgctca tgttaataaa gatgggaagc
     5281 ttcaacatta ttatgttatt tataaaagca ccaaggatta tctgataatt ggagaccctg
     5341 atccaagtgt aaaagtaact aaaatgacta aagagcgttt tgagaaagag tggacaggtg
     5401 ttactctttt tatgggaccg gaacccagtt ataaaccaca taaggataag aaaaatggac
     5461 tctgggactt tctccctttg atctttaaac aaaggtcctt gatagctaat attgtctttg
     5521 ccagtctctt ggttacttta ataaatattt taggttccta ttatttacaa ggtattctag
     5581 acgaatatgt ccctaatcaa atgaagtcta ccttaggaat tatctcaatt ggattagttg
     5641 tgacctatgt tttacaacaa atgatgactt ttgcaagaga ttatctctta accatactga
     5701 gtcagcgatt gaccattgac gttatcttgt cctacatacg acatatcttt gaactcccaa
     5761 tgtctttttt tgccacaaga cgtacagggg aggttatctc acgttttagt gatgctaact
     5821 ctattatcga tgctctggct tcgacgatat tatcactttt ccttgatttc tctattgtga
     5881 ttatcgtagg aggcgtgtta ttgatacaaa atagcaatct cttcaagcta gttctttgtt
     5941 cggttccaat ttataccctt atcgtctttg cctttatgaa accttttgag ctaatgaatc
     6001 atgacgtcat gcagagtaat gctatggtta attcagccat cattgaggac attaatggga
     6061 ttgaaaccat aaagtcacta accagcgaag aagtatgcta tcaaaagatt gatggtgagt
     6121 ttgttgacta tctagacaat tcttttcgcc tttctaagtt atctatacta caaacatcat
     6181 tgaaacaagg tgctcaactt attttaaatg tacttatcct ctggacaggt gctcagttgg
     6241 tgatgggaaa taccatttcg ataggacaat tgattacttt taatatgttg ctttcttact
     6301 tcacgaatcc tttggaaaat atcattaacc tgcaaaccaa gttacagtct gctaaggtag
     6361 ctaatactag gctcaatgag gtctatctga ttgaatcaga gtttggacaa agtgatgata
     6421 cctatcaaga aggcattgcg gatggagata tcactgttac ggatttatct tataaatatg
     6481 gttttggtcg tgatactttg actgatgtca gtttgacgat tagacaagga gaaaaaatca
     6541 gttttgttgg tgtcagtgga tctggtaaga ctactctagc taaaatgttg gtcaattttt
     6601 atcaaccata taaggggcac atagatttta atggtcaaaa tattagtcgc atagacaaga
     6661 aaactcttcg tcaacatatt aactatctcc ctcagcaatc ctatatattt agtggtagtg
     6721 ttttagaaaa tcttacttta ggtgcagcac ggggtattac gcaagctgat attttgaaag
     6781 cttgtgaaat agcagaaatt cgtcaagata ttgaaaacat gcctatgggg tttcagacag
     6841 agctgtctga tggagcaggt ctgtctggag ggcaaaagca acgtatcgct ttggcgcgtg
     6901 cactactaac gaaatctcct gtactaatct tagatgaagc aactagcgga ttggatgttt
     6961 tgacagaaaa gcaggttatt gataacctcc tagcactaaa agataaaacg atcatctttg
     7021 tagcacacag gcttagtatc gctgagcgga ccgaccgtat cgtagtcatt gatcagggac
     7081 gcgtagtgga gacaggttct catcaagacc tgatgtctta tccaggtttc tattatcaat
     7141 tatttagaaa gtgaggaaaa ggaaacacga tgaatccaca gttgtttaaa agcacagagt
     7201 tttaccatcg tcgctaccac aatatgtcta ctgttttgat tactcccttg attttgttag
     7261 ttattttcct ttttcttttc gctttttttg ctaagaagga agttacagtc acgtctagag
     7321 gaagtataga gccaaccaag gttatcgcag taatccaatc aaccagtgac aataccatca
     7381 tagataatca actggttgct aataaggttg ttaaaaaagg ggacacctta gttcagtatt
     7441 cagagaccat ggaggcatcg caaaaagagg ggcttcaaaa gcaactagaa cttttaaaaa
     7501 gataggaatc aggtttgaag accttgcaat ctagcctaac gcagggaacc aatcttttcc
     7561 aagaacagga agacgagttt ggttatcaga gtacttttaa cacctaccta agtcaggcac
     7621 aggattattg acttgggtgt ggctaaaaca aatacagagg ttaataacca agcagcaatt
     7681 gcgagtaata ccggttctgc tattgataac cagattagtc aattgcagac tcaggtctca
     7741 gagtatgagg cgctctctca agctattacc aatcatgaaa cgactttacc tgaaggcaat
     7801 cctcatcagg caaccttaaa tgcctataac agtcagtatg ctacgacacc ggatgccagt
     7861 gtaacagacc aatacctatc tcaagttaat accaatattt cgagcttgaa tgcttccata
     7921 ggtaatctag aaatccaaaa ggctgggaca ggcacagctg taacttatga caatagtgat
     7981 agcactaaaa aagaagctct aaaaaatcaa ttcttgcaaa atgcaggaca gcaattgagc
     8041 tcagtggaaa cacaaattac cgataccgag agtaaaatca atcaggcaga tgtccttctg
     8101 actaataccc tcatccagtc accagaagat ggaatcttac acttgagtca agctgataaa
     8161 aaagcaacca tggctgcgac aggaactgag ttggcccagc tttatcccga tatgactcaa
     8221 acccaggaag ttgccattac ttattatgtg aattcggatt atgtgccaaa actgcaaaaa
     8281 ggccagtcag ttcgactgac cttggataag gttggtaatc acggtaccac aattattgga
     8341 aaacttgaga gtattgataa ttctgccacg gaaacagaaa gggggaatgt gtttagagta
     8401 actgctaggg caagtatttc agaaaaagaa gcccaaaatc tacgttacgg tctagaaggt
     8461 cgtgtgacaa gcgttattga ccaaaagacc tacttcaatt actttaaaga caagttacta
     8521 aacttgcaag accaatagga ggagaattac tgatggctaa caatacgatt aataactttg
     8581 aaacacttga taaccacgct cttgaacaag tcgtaggtgg aagtgggtgg atggattata
     8641 taaatggttt cctaaaagga ttcggagggc aaagaacgct tccaacaaaa gactataaca
     8701 ttcctcaagt ttaggtatag aaaaaaggct gttaggcctt tttagttatt gttaattgtt
     8761 gtgtgaatga gaaattgtta ctctgtgttt ctaagtttac attgatatag ttatctaaga
     8821 tttctgtgac attagcaagg ccaatgcctc gctctcgtcc cttgttggag acacctcttt
     8881 caaatatggt tttagtttct gtttgttctt cacttatggt attgctaata gataatagct
     8941 gtgaacgatg atcttcccaa aagctaatag taattttatg gttttgagtt tgaatggcac
     9001 cttcaatagc gttatctaaa aaaatagaag tgacgataat gaagtccaga atctccatcc
     9061 caatcaagtg gatgggttct gggatgctaa tctgagcttc aataccttct tcttctgctt
     9121 gtaaaacttt tgcggacaga aggcttttca aagtattatc ctgaatatta acgagtctag
     9181 ctaagtcaaa gtttcttgta tttaatcgtt tatcggattc ttgaagcaca ctatcataga
     9241 cttctttgac aatatccata tcgtctttat ctatccccaa tcgtaatgtg actaagagat
     9301 tactataatc gtgtctaaaa ctacgaacag aattgtagag acattcaata tgtttattgt
     9361 aggtgtagag attctctagc tggagatttt tctggaagtc caattgtcct tgaatcattt
     9421 cacgaatgtt tctttctaaa aagacaatca taatgaagaa gaggacaagt gaaataacaa
     9481 cacagagttt tcgaagctcc aaagttgaag agtgagtagt gttttcaaga tacatgaggg
     9541 actgtaacag tagggtgtac ccaaacataa aaaagttagc aactataata atatgttgaa
     9601 tcggagaatt tgatttctgc ttttgaagta tggtaaaact ctccttgaat aatttaataa
     9661 agagaaatga tagacaaaga ggtgcgatag atgaagggat ggatattaat agagagcttt
     9721 tataatcggt gatactaata ttaaaaaaag gaaagataaa aaaagtaatc agtcttaaac
     9781 taaggttgtt gaggatatca gggaagagac cattgaaaat ctttattttt aatggttttt
     9841 tagtcttagt ggataaaagg aaggagagca gaagatagta gatatcctca ccccagaatt
     9901 taatgataaa ccaagaagag tggttataaa taaaattaaa ggctaaatta aaaataagga
     9961 gtaggaaaaa atacctcaga cgaatcttct gtcccattaa ataaaggaaa agaataattt
    10021 ctaggcctgc acttaaaagg gtgagaaaaa gtagccataa cgttgttaac atcatctgcc
    10081 tctttcctca acaatctgtg caatctttcc tatcttcata cgggatactg gtagaacttg
    10141 accattaatt aaggtagctt cataattggt cttgttgaca gagatgatca tatctgtatt
    10201 gacgatatag gaccgatggc atgggtagag ctttttgtgt atctttttaa agtctgccag
    10261 atttgctcgg atatccatga gggtatggat agtctggagg tgaacatggt gtttgatatc
    10321 tgatgtggat aggtatagaa tttgatccat aggaaggttt attaattgag actctgtttt
    10381 gtagagaaaa aactcatccg tggtagttgc gttaataggg aagacttgag caatggtttc
    10441 ccctatttct tttctaaagc tagcttcatc taaggtttta ttgatgtatt tataggctgt
    10501 aacgccaaaa gcttgaggca tgaactctat atgtgtagtg acaaaggcaa tgatagcata
    10561 agggttattt tgacgtacga ttttagcgat atcaagtccc ttcttatctt cacctttaat
    10621 ttcaatatca agaaagaaaa tctgatcgct tgtattagaa gtgatagctg ataacaactg
    10681 gtcaggtttg tcaaaagact ggacacaaga tagatctttt ccgaaggatt taagttcatg
    10741 tgccacagcc tcttccaagc gacccatctg aatagaatta tcttctaata ggtaaatctt
    10801 caaggtctag tcctctcttt tatgacgaat actgtttatt gaaaaattgt aacataaaga
    10861 aaacggtttt tcattttttt atgagtataa aatgagattt ttttctgaat tttagaaata
    10921 atatacatta ggaattacca ttcgggacat atagccactt tttgggacgc tagctctgat
    10981 agagacaatt gaatgctata ctaaagatgt gattgagaga tcacacgata aaaattttag
    11041 gaggtagttg ccatggcaac tcaaacaatt gaaaacttta acacccttga cctcgaaaca
    11101 cttgctagtg ttgaaggtgg tggatgtagc tggggaggtt ttgctaaaca aggagtagct
    11161 acaggagttg gtaatggttt acgactaggt atcaaaacac gtacttggca aggtgctgtc
    11221 gcaggagcag ctggaggtgc tatcgtaggt ggtgttggtt atggagcaac atgctggtgg
    11281 tgatggatta tgtttgattt gaaaagttat attttaggga tggtttccat ggctgttatg
    11341 agttttttag ataagccaat tatgtcattt cttgaaaaac acaaggctac caattccgtt
    11401 aagaagaaat cctaactgaa atgtcttgtc aattgctggt ctgtgaatag catgtgaatt
    11461 atgattgaaa atttcgatat aagagaagag gtatttgtaa tcatgaccaa aaaacgccta
    11521 gtgtctctaa tgatgtctat gggcttcgtc cttgttgcct tacataactt tggagaaaaa
    11581 ctgaattttg gacttcaatg cctaaatctt atcgggttat gtttatttct ttttcttatg
    11641 tgtacggtta tcaaggatat aaggtcagac aagtagtgac atttatgtca ctactttttt
    11701 atcggcttcc aatctataat aaaattcata gattatgcac agactagcta aaaacacttt
    11761 aaggagaaaa gtatgtttaa aaactcaaaa ccgtatttac tggctaccat tctcatcgta
    11821 atgggcctcg ctaatctatt tagaagcttg gatgcagttc accataccat taacttgcta
    11881 gggctaacgg tgcttcttta tagcttactt tttaaaaagt gggtacagtt tcaaaagtaa
    11941 cctttggtca ctttgaacgt aagatgcttg caaatgctta tttttgatgt tcccgaagta
    12001 aaattattct tgctaatgat agcggagatt atattatatt tgattgcata tctttgtaat
    12061 agagaaaaca aagatatgta tattcgccta tttaaagtat cagtactaat gacactactg
    12121 tattacatct ccagtagaat ttaatcgcta agggcttact tgaaatctta cagctgtata
    12181 ataaaataca gagaggaata gagttaaatg taatagctta ttaggtttgc aagactgact
    12241 gaggttattc atagtttagg tgttttatca tgaagttaaa gaatattagt tcgagtgtat
    12301 tgcgatcttt tagaaccatc actgctgcgt tggcagtttt ccttataagt atcagccttt
    12361 ctctctacaa aagcaagatc tcgccaggaa cttggctagc agtcggagca ctagctttcg
    12421 tagtcatttt tgttaatgga ctgctctacc gtatgcttaa gaagcgtcca gattcagtaa
    12481 atctgttaac aatacggcag tccttcattg tctttcctgt catcacattt ctagtgctta
    12541 gtgtagagtt ttacacatta ctaacattca gtgataccac agaccgtata gtactagccg
    12601 tattaatgct tttgttaatc ctctgtgatt ttctatctta ccttcaagtc aaaaaatatt
    12661 ttaaacaata aacgcatttg cttgattatt ctgtaagcaa tctataagat atttgcataa
    12721 aagtgttata ataagaaagt gattaagtaa atatgtgaaa attagaggaa gatttccaat
    12781 gattgaagga tgttctttag gaattaccat tcgggacata tagccacttt ttgggacgct
    12841 agctctgata gagacacttg aatgctatac taaagatgtg attgagagat cacacgataa
    12901 aaattttagg aggtagttgc catggcaact caaacaattg aaaacttaac acccttgacc
    12961 tcgaaacact tgctagtgtt gaaggaggtg gatgtagttg gagaggcgca ggtggagcga
    13021 ctgttcaagg agctatcgga ggagcgtttg gaggtaatgt agttttacca gttgtaggct
    13081 cagttcctgg ttatctagct ggtggtgttc taggtggtgc aggtggtact gttgcctatg
    13141 gagcaacctg ctggtggagc taatctatgg tatattttat tataggtttt gttgttgctt
    13201 tgttaggtaa tatctttttc aaaaaggtca ataaaaataa acataaaaaa taatcttgaa
    13261 catatactga acagctccct gtcaagtgga caatgaaata ataaaatatt aggcgacggc
    13321 cttgttcctc atttcaagag gggcaaggcc gttattgcgc tcttgaaaac gttgatgatt
    13381 gtaaaaatag atgtaggcat caatatctga aactagctcc tcaaaagtct tatacttctt
    13441 caaatcatag cactccgtct taaagtgccc aaagaaactc tcaattggtg cattgtcaat
    13501 acacttacca acacgagaca tggagcgggt catctgatac tgggtagtta aacggtaata
    13561 atctttcgaa gtatactgcg aacctcggtc gctgtgaatt aatggtgtcg cattaggatt
    13621 agctttttgt gctttacgaa gtgtttccaa taccaattcg ttatcattaa attgaccaac
    13681 tacataggcg acaattgagc cgtcgtaaag atccttaata gcactcaaat aggctttaca
    13741 gctgaaaccg tacttcaaga aagtcacatc tgtacaccat ttctgatttg gagcagtggc
    13801 tgtaaaatta cgattgagaa tgttgtcctc tacattgaca aagctagttt tagtacaata
    13861 gcccttggct cttctgataa tggaacgtag acctagaatg tgcatcaagc gtcgaatccg
    13921 cttcttgttg tagtttgttt caagcttgcg attgacaaat agcgtcatac gacgataacc
    13981 aagaatacca ttatgctggc tatgaagttt cttgatgata tccatcaagc ctaaattttc
    14041 ctgttcagaa gttgtttctt gatgttgtaa ccacttgtaa tagcctgagc gagatacctt
    14101 tagaatatgg cacaagtggc tgatagaaac ctcttcatac tcatccgcat attctttaat
    14161 cgcttggaag gtttccaagt gccgaccaag tcttaccgtc ggtttcgtcg tttgatttct
    14221 tctaactttt ttagcaggcc gttctccatt tcaagatact taatccgctc ttcctgttgc
    14281 ttgattttga ggcgtaactc ttcttctgga gtaaggtttg gtttacttgt aagacctttt
    14341 ccacgacgat ctaggagacc gttagaaccg tccttctcga actttctgac ccaagaatag
    14401 atctgctggt aggaaacacc atacttctca acagcccctt ggtaatcttt ctcgtgggca
    14461 agggtaaaat tgacaatctc aattcgttct tcaaatgttg tcttgcgtcc ttgcttcatg
    14521 cgtctcattc ctttactagt agctttcagt tctttaccac tagtataact ttttatccat
    14581 gatctgagaa cataagggtc agaaattcca tattttttgg tcagatcttt gagacttccc
    14641 aagccattaa gatagtcgga aacagcttgt tcctttagtt ccttactata cttcttccat
    14701 tgacggcttt cctctagccc atcaacacca gcttctttgt acttccgaac ccagttcgat
    14761 agggtgtctt tagagatacc ttggtttcta gttaaccaac taagtgattt accttcttcc
    14821 aagtgaagca gaacaatttc tagtttctca gatacagatt ttggacttct tttggacata
    14881 ataagactcc ccttatagtt tctagtgaaa atttttattt tttcactgtc cactataagg
    14941 ggagtatatc atggtgatag tgggattttt tatattctta ccattcggga cgtatagtca
    15001 ctttttggga cgttagcttc tatgagagtt gtaaattgtt aaactagact aagtaatcga
    15061 aaggagttta tgatgaaaaa aaggacatta acgctatgga tgatgagttc agccttgtta
    15121 ctgaatctat cggtaggaac tgctttagcg gatgaggtgg tagaaacggg agctgataat
    15181 tctccaaagg ttgaagcaac cgaatctact ccagtagaac aaccatcaga tagtcaggag
    15241 cagtcgcttc ctgaagataa agaggcacca gcagcgactg aatcagtaac cttggctgag
    15301 tctgaggagg agactgcaaa aaatgatatc ccagcagtat ctcgtgagga atacgacgct
    15361 aacgttgctg atttacctaa aataagttta gatgatgtgc gtaatgcctt taccgaggat
    15421 ggtcaggcac atacgattta ttttggacgt ggaacctgtt actattgtcg tcaattttca
    15481 ccagagttga aggtcttgaa ccaactgatg gatggtcgtt tagagtatta cgatatagat
    15541 cgtgaggatt ttgaccgaaa ctatgtgttt ggtgagattg gtattccagg tacacctaca
    15601 ctactttatc tggaaaatgg tcagctatta tcaggatggg ttggtggtgg acctgctcaa
    15661 acagtttatg accatttagc cagctctagt ccacgtttta tgactttgaa tcaggaacaa
    15721 acaaccatct ctgaacctca aactaaaact gttcgtccta cacgagtaac cgaagagagt
    15781 acgaaagaga aatctttgcc aactgttcaa ccacagccga tgtcaacggt tcagaaggaa
    15841 ctgaacgctc aaacagggca aatggcacca atgactgata aagtagcaga cacaaaagaa
    15901 ttccctaaaa caaatgacgg tgagcaatca cttgtctctt ttgtgggggc attagcaatc
    15961 ttagcttcac tcatgttagc actgagatat tatattaaat aggttaaaag attgagtatc
    16021 tccctcaatt tttttcattt tgtatatgaa tgaccattca ggacgtatag ccactttttg
    16081 tgacgctggc ttttaaatga ctatcagtgt gctatactaa agatgtgatt gaaaaattag
    16141 ttgaaagaaa taaggaggtt ttcttaatga aaggacttaa atggtttgca ggaggcaaag
    16201 agagacaaga acaagcagta gctatcatcg atgaggtaat tgaaactatt ggagataagc
    16261 cagattatgc tgatttgaag cag
//
