LOCUS       c00047_gnlPro..        23514 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JMNGEONE_47.
ACCESSION   c00047_gnlPro..
VERSION     c00047_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 22:47:27
            Original ID  :: gnl|Prokka|JMNGEONE_47
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 21994
            Orig. end    :: 45508
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23514
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[31994:35508]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13514
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..23514
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23514
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             183..1322
                     /locus_tag="ctg47_15"
                     /transl_table=11
                     /translation="MAITIKKVSTKRELKKFIRFNYRMYKGNPYSVPDLYDDMLNTFNK
                     KKNAAFEFCEADYFLAYRDDKIVGRVAAIINNQANEKWECKNVRFGWIDFIDDPEVSSA
                     LIKTVEEWGKERGMTHIAGPLGFTDFDAEGMLVEGFDQLSTMATIYNHPYYPVHMEKLG
                     FEKDADWVEYKIYIPDAIPDKHKRISELIQRKYNLKIKKYTSGRKIAKDYGQKIFELMN
                     EAYSPLYGYSPLTQRQIDQYVKMYLPILDLRMVTLITDANDELVCVGISMPSLAEALQK
                     SHGRLLPLGWFYLLKALFMKRRAKMLDLLLVAVKPEYQNKGVNALLFSDLIPVYQKLGF
                     IFAESNPELELNGKVQAQWDYFETQQHKRRRAFIKEINN"
     CDS             1414..3291
                     /locus_tag="ctg47_16"
                     /transl_table=11
                     /translation="MEENELIPVDNNNAVEYTDDNIRHLSDMEHVRTRPGMYIGRLGDG
                     AHAEDGIYVLLKEVIDNSIDEFKMQAGKKIEITVEENLRVSVRDYGRGIPQGKLIEAVS
                     MLNTGGKYDSKAFKKSVGLNGVGVKAVNALSSRFEVRSYRDGKVRTAIFSKGNLLSDNT
                     QDTEEENGTYIFFEPDNTLFLNYCFKPEFIETMLRNYTYLNTGLAIIYNGHRILSRNGL
                     VDLLNDNMTATGLYPIIHLKGEDIEIAFTHTGQYGEEYYSFVNGQHTTQGGTHQSAFKE
                     HIARTIKEFFNKNMDYTDIRNGLVAAIAVNVEEPIFESQTKTKLGSTNMVPGGVTVNKY
                     VGDFIKQEVDNFLHKNADVAEAIQQKIQESEKERKAIAGVTKLARERAKKANLHNRKLR
                     DCRIHLNDPKGKGLEEDSCIFITEGDSASGSITKSRDVNTQAVFSLRGKPLNSFGLTKK
                     VVYENEEFNLLQAALNIEDGLDGLRYNKVIVATDADVDGMHIRLLLITFFLQFFPDLIK
                     KGHVYILQTPLFRVRNKKKTIYCYSEEERVNAINELSPNPEITRFKGLGEISPDEFKHF
                     IGKDMRLEQVSLRKTDAVKELLEFYMGKNTMERQNFIIDNLVIEEDLAS"
     CDS             3288..3743
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CTP_transf_like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg47_17"
                     /sec_met_domain="CTP_transf_like (E-value: 5.1e-21,
                     bitscore: 66.7, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKAIFPGTFDPFTIGHYSVVERALTFMDEIVIGIGINENKNTYF
                     PIEKREEMIRELYKDEPRIKVMSYDCLTIDFAQEVGARFIVRGIRTVKDFEYEETIADI
                     NRKLAGIETILLFTEPELTCVSSTIVRELLTYNKDISQFIPKGMRIS"
     CDS             3827..5422
                     /locus_tag="ctg47_18"
                     /transl_table=11
                     /translation="MNKIKIYVLLACLWAVSALQAQNFGSEAMRKLQMAEFAISHFYVD
                     KVDEDKLVEEAIIKMLAQLDPHSTYSDAEEVKKMNEPLQGNFEGIGVQFQMIEDTLLVV
                     QPVSNGPSEKVGILAGDRIVAVNDSAIAGVKMSTEDIMKRLRGPKGSKVNLTIVRRGVQ
                     DPLLFTVKRDKIPILSLDASYMIQPKTGYIRINRFGATTAEEFKKAMTSLQKQGMKDLI
                     LDLQGNGGGYLNAAIDLANEFLGQKELIVYTEGRTAKRSDFYAKGNGDFRNGRLIILVD
                     EYTASASEIVSGAVQDWDRGIIVGRRSFGKGLVQRPIDLPDGSMIRLTIARYYTPSGRS
                     IQKPYDSTVDYNKDLIERFNHGELMNADSIHFPDSLKAQTKKLGRTVYGGGGIMPDYFV
                     PIDTTLYTDYHRNLVAKGAVIKFTMQFIEGHRKELKNKYKKFESFDEKFVVDDDMLATL
                     KEIGEKEGVKFNEEQYQKSLPLIKTQLKALIARDLWDMNEYFQVMNTTNESIQKALEIL
                     NSDEYQKKLKQGIQ"
     CDS             6101..6739
                     /locus_tag="ctg47_19"
                     /transl_table=11
                     /translation="MAIQFELYKTPRPKDEEDKEVYHARVVNFQHIDTDYLAKEIQIAT
                     SLTEGDVKSVLESLSHFMGDRLREGQSVHLDGIGYFQIKLNSQEPITSPKLKANQIKLK
                     ANISFKADAKLKRSVSVVHVERSKLKPHSAVLSNDEIDKLLTNYFKSNPVLTRRDFQGL
                     CGFAPTTAARQIKRLKEEEKKLKNINTYYNPIYVPMPGYYGKAEIKTDE"
     CDS             6767..6910
                     /locus_tag="ctg47_20"
                     /transl_table=11
                     /translation="MKSEEIKELFKQFESIVCEYNKVECWSARELYPLLGYSQWRNFLS
                     II"
     CDS             6977..7555
                     /locus_tag="ctg47_21"
                     /transl_table=11
                     /translation="MVILGSGAEREVDNIFLTRYACYLVAQNGDSRKQEIAFAQNYFAI
                     QTRRAELVEQRLIEYERVQARTKLAETEKLLSGVLYERGVDNQGFAIIRSKGDKALFHM
                     DTKMLKRKLDVPDSRPLADFLPTISIKAKDFAAEMTSVNVQQKDLYGQTAIENEHVDNN
                     VAVRDMLVGRGIFPEQIPANEDIAAGVFL"
     CDS             complement(7684..8640)
                     /locus_tag="ctg47_22"
                     /transl_table=11
                     /translation="MLRKIVFFLFVFVGLSLFAQQDYMVSSYVRGNFYNRGRISTESLR
                     ASNDLIFLNVHPNKDGSLSFENPRVFQGKGVTTWEGLIKSVRAKVKGTKVKIRLGASSG
                     EWKAMVADEAARTTFAKNIKTVLEKNKLDGIDLDFEWAENEKEYKDYSLAILKMREVLG
                     DKYLFSVSLHPVCYKISKEAIEAVDFISLQCYGPSPVRFPIEKYCSDIQMVLEYGIPKE
                     KLVAGVPFYGVTKDNSKKTEAYFNFVQNGLVTSPAQNEVIYQGDTYVFDGQDNIRIKTR
                     YAKEQKLKGMMSWDLATDLPLSDSRSLLKTMTEELRE"
     CDS             8920..9789
                     /locus_tag="ctg47_23"
                     /transl_table=11
                     /translation="MPGDSFCIQYTNCTGCPKNVENILVYRNLPKGEHIPKDKCTQNCM
                     LFMIKGELLINSEEHPGITLRERQIVLQAIGSKVEILALTDVEYVVYWFNELPLLCEDR
                     YREMMEQAEAPLTYTPLIMSERLYHLVTSMPEFLAEENPCSKYIDLKCKELVFLITNFY
                     PLPQLSSFFYPISTYTESFHYFVMQNYSKVKNVEEFAHLGGYTTTTFRRLFKNLYGVPV
                     YEWILEKKREGILEDLQHTKMRITEICNRYGFDSLSHFAHFCKDSFGDTPRALRKKAAG
                     GEKIGKVQ"
     CDS             10001..10705
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg47_24"
                     /sec_met_domain="SucD_FumR (E-value: 2.1e-131, bitscore:
                     426.6, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLSNSSVGRKVVMSVTGIALVLFLTFHMAMNLVAIISADGYNMI
                     CEFLGANWYALVATAGLAALFVIHIIYAFWLTMQNRKARGSERYAVVDKPKTVEWASQN
                     MLVLGLIVIVGLGLHLFNFWAKMQLPELMHNMGMHADTLTLAYAANGAYHIQQTFSSPV
                     YVVLYLVWLFALWFHLTHGFWSSMQSLGWNNKVWINRWKCISNIYSTIVVLGFALVVVV
                     FFVKTLICGGAC"
     CDS             10743..12722
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 202.3; E-value:
                     4.6e-62)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg47_25"
                     /sec_met_domain="FAD_binding_2 (E-value: 2.7e-62, bitscore:
                     202.3, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 3.1e-37,
                     bitscore: 118.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKIDSKIPEGPVAEKWTNYKAHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLGEMGFRVFNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTVKG
                     GDYRAREANVYRLAEVSNAIIDQCVAQGVPFAREYGGTLDNRSFGGAQVSRTFYAKGQT
                     GQQLLLGAYSALSRQVNVGTVKLYTRYEMQDVVIVDGRARGIIAKNLVTGELERFAAHA
                     VVIATGGYGNAYFLSTNAMGCNCTAAISCYRKGAVFANPAYVQIHPTCIPVHGDKQSKL
                     TLMSESLRNDGRIWVPKKKEDAVKLQKGEIKGSDIPEEDRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNNTGLAVFLDFSEAINRLGIDVVLQRYGNLFDMYEEITDVNPGE
                     LAKEISGVKYYNPMMIYPAIHYTMGGIWVDYELQTTIKGLFAIGECNFSDHGANRLGAS
                     ALMQGLADGYFVLPYTIQNYLADQITVPRFSTDLPEFAEAEKAVQAKIDKFMSIQGKES
                     VDSIHKKLGHVMWEYVGMGRTAEGLKKGIAELKEIRKEFETNLFIPGSKEGMNVELDKA
                     IRLYDFITMGELVAYDALNRNESCGGHFREEYQTEEGEAKRDDENFFYVACWEYQGDDE
                     KAPVLHKEPLVYEAIKVQTRNYKS"
     CDS             12759..13514
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg47_26"
                     /sec_met_domain="Fer4_7 (E-value: 2.7e-12, bitscore: 38.5,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 1.9e-25, bitscore: 80.3,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.2e-06, bitscore: 20.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKNISFTLKVWRQAGPKAKGAFETYQMKDIPGDTSFLEMLDILN
                     EQLISERKEPVVFDHDCREGICGMCSLYINGHPHGPATGATTCQIYMRRFNDGDTITVE
                     PWRSAGFPVIKDLMVDRTAYDKIMQAGGYVSVRTGAPQDANAILIAKPIADEAMDAASC
                     IGCGACVAACKNGSAMLFVSAKVSQLNLLPQGKPEALRRAKAMLSKMDELGFGNCTNTR
                     ACEAECPKNISISNIARLNRDFIIAKLKD"
     CDS             complement(14139..14978)
                     /locus_tag="ctg47_27"
                     /transl_table=11
                     /translation="MPSICQGTWDCQICPKAVSNAITHVIYQRGFHKPAQKCEENLILF
                     LMKGEILVNSKEYAGTMLKEGEFILQAIGSMFEMLAMTECECIYYRFIQPELFCDFRFN
                     HIMKEVSPPLIYTPLKIIPELQYFLNGSITYLKGDKVCRDLLSLKRKELAFVLGYYYSD
                     YDLSSLVHPLSKYVNSFQYFVIQNYKKVKTVEELAQLGGYTLSTFRRIFNNVFHEPVYE
                     WMLARRKEGILDDLNNSKCSISEICYKYGFESLPHFSNFCKKSFGASPRNLRRQDIS"
     CDS             complement(15194..16192)
                     /locus_tag="ctg47_28"
                     /transl_table=11
                     /translation="MKKILLAVTAALAITGCSQNEEFENAGQNAVINFESIVSNATRAT
                     EMKLDELKTQGFHVYAYNTGDAVVGTGTLNKSIMENEPVSWNSGDNKWTSNNAYYWPSQ
                     GKIQFFAYSSSRSLTLTATDTDQYPTLVNYQIADTAPNQEDLLVAKVTDKTKADLSVNF
                     TFSHVLTQIQFAIKSKLDDKLTYTVSKIEINGVNDKGTYKYADNVWTSLEGSATYIYPL
                     DDITTTNNAVQGTTSKNIGTESLMLLPQTLTTRKMLVSYNVTDKNGDEVYTTGATPKEV
                     DLKDAIWGVGKSIRYTLSLTNDAATIGWDVTDVDKWADEDNQEKDPVAPAV"
     CDS             complement(16247..17221)
                     /locus_tag="ctg47_29"
                     /transl_table=11
                     /translation="VLLSSLLMLTGCSRRDILDDYPVSGVDIKLDWDGVTDQLPEGVRV
                     IFYPKNGDGRKVDKYLSVRGGEMKVPPGRYSVVVYNYNTESIRIRGEESYETIEAYTGN
                     CNGLGIEGTEKMVWSPDSLYVLNIDELEIEKSEEVLRLDWKLESVVKKYSFAVEAKGLE
                     YVATVVGSIDGLSDCYCIGKGRGVCSSQPIYFEVRKGDNKVTASFTAFKQVKEMTMPTR
                     MSTSERETSSEKDAIILILKFIKTDNTVQEATIDVTEIIGTLENAGTGEDGKPTPPPEI
                     ELPPDDKIEVDKPETPPNPDGGGGMGGNVDGWGPEDNVELPVN"
     CDS             complement(17258..18502)
                     /locus_tag="ctg47_30"
                     /transl_table=11
                     /translation="MALLSLPESGYASIPFFAVANDTIRRAVIYFDANEAKVDLSYKDN
                     NQAITILDSLLLGNLNTKYITALNVKTFVSPDGDESYNRSLAARRNDSIKEFLQRYNSD
                     VSVDKIHFFSEGEDWSEFRKLVASDSNLPDREEVLILIDYHKNDVNKRKQLLRKLNRGI
                     AYRYIVRNIFPELRRSVITIVGETSKLGKEAFEPVSSVSGLFVSKQEEALPKDQPDKPV
                     GESEEKQACEVDISEAEGPVKSQTVLAVKNNLLYDLALAPNIEVEIPIGKRWSLNTEYK
                     CPWWLNSKHDFCYQLLSGGMEGRCWLGNRQKRDRLTGHFIGLYAEGGIYDFQLRGDGYQ
                     GKYYGAAGVTYGYARQLARHFSLEFSLGIGYLTTEYKKYTPYEGDIIWTNSGRYNFIGP
                     TKAKVSLVWLITTKK"
     CDS             complement(18783..19352)
                     /locus_tag="ctg47_31"
                     /transl_table=11
                     /translation="MKILQISDTHNQHRQLTDLPAADVIVHCGDFTDNGTEGEVLNFLN
                     WFIELSYPHKIFITGNHDLCLWEAEGIEDLPNNVYFLQDCECEIDGIKFFGLAYNHPET
                     LISNDVDVLITHEPPIMILDESAGIHWGNVLLRNKVYEVKPHYHLFGHAHEGYGTFKDE
                     HIIFSNGAILDDHYNSCHKPKLIIYK"
     CDS             complement(19349..20611)
                     /locus_tag="ctg47_32"
                     /transl_table=11
                     /translation="MNLIIHRGADQIGGCITEISTENCKILIDFGSNLPGCKKEELTEE
                     QVKSIIGNADAVFYTHYHSDHVGLHHLIPTNVLQYIGVGAKEVMLCKYDALRGHGDYSK
                     QIEAIERMETYCAAKRIDVSKKGKIFVTPYFVSHSAFDAYMFLIECEGKKILHTGDFRR
                     HGYIGKGLFPTLKKNVGEVDILITEGTMLGRSQECVISESEIQKNIIKALREHKYVFAL
                     CSSTDLDRLATFHAACKKTGRIFLVDEYQNRVLNVFTKYAGCKSDLFQFNAFKLINYRT
                     VNVRNKLQKEGFLMPIRMSSGYLLKGMLDIYNDEKPWLIYSMWSGYAKEGKDYTNSDVI
                     NIRNLFGDRILDGTMDGVHTSGHADVETLKEVCQTVHPRIGVIPIHKDENSRYDSISGI
                     SSYFIFDEGDVDIHDIHISVK"
     CDS             complement(20608..21633)
                     /locus_tag="ctg47_33"
                     /transl_table=11
                     /translation="MEKLKMVNNYTIRTTYYDRKMDEKLLTQINERFPWIISYVKSHNC
                     LDFQTGNDPKTNRSWFSIYRGTGRILTFRSHSGKVNELCDVAEAYKELMQPDFFRNPTP
                     DQFDTYLTKIASTEKFKRYYEDTKGVRNEGFYQTLIGRRYTFEVKDTDDFILFDKELVI
                     GFKTKDIKDEWNKEIVDQQTLKIEQLRKTYNGTLPEEIKPEYGEFDFLGLNTNGDILIM
                     ELKQNDPAKTALSPIQTSYYYLQFQKLAREDDKLYQRIKAMIEQKIDYGLIDSSYKNKI
                     PLKLSGRIIPCVIVGEDNRLSETICERYRFIRDLFLPEMKAYTYIREEGTLVTSEKLEA
                     E"
     CDS             complement(21694..22449)
                     /locus_tag="ctg47_34"
                     /transl_table=11
                     /translation="MHREAIAELFGVEVECDTSSYEYYISSSSQLKNDKTRQWLLNSFT
                     VSNMIEAGRNMKDRILFEEIPEGTEYLQTVIDAMQRKKELKIDYKPFNGHQSIFHLQPY
                     AMKVYHQRWYVVGYLKEQEGIRNIALDRTLEMELTDDSFILPNDFDAEEYYAHTVGIFV
                     NDKLKPQKVVVRAFGVHVEYMRSLPLHFSQQEIRTEHKEYSDFEYQLCLTPELTSQLLA
                     MGEKIEVMEPIGLREEIRKRLFAAINRYK"
     CDS             22817..23383
                     /locus_tag="ctg47_35"
                     /transl_table=11
                     /translation="MCATFLHTSPLFLHTHFNILFVMAYKKNPKKKDALNIKRAVESLR
                     FQIDWGLKLLGAKKGDLFHQLAKVEVDLISELNLTQDILAIKSLVDGVKQNLQIEPTPE
                     SGDFTHSIVALALGIASISHLNNISLPESWRDQIEKKLLTIYYPEKLRNKIVDWAKANG
                     YSTSNYLGRPIVKFNQLYLIIERTR"
ORIGIN
        1 gtggttttgc gggtaatgtt tattgctttt catcgaagta aactccctct tcactatcat
       61 aatgcataaa ctcaaatggt acataagcac taaaattata tagatacagt ttttgccacc
      121 ccacacgttg taatttaaag attatcacgt atctttgcct gctcaaatca taaatacgag
      181 atatggctat tacaatcaag aaagtctcca caaagagaga acttaagaaa tttatccgtt
      241 tcaattacag aatgtacaag ggtaaccctt actctgtgcc tgacctctat gacgacatgc
      301 tcaacacctt caacaagaag aaaaacgcag cattcgaatt ctgtgaagca gattatttcc
      361 tcgcataccg ggacgataaa atagtaggac gtgtagctgc aatcatcaac aatcaggcga
      421 acgagaagtg ggaatgtaaa aacgttcgtt tcggatggat agacttcatc gacgatcccg
      481 aagtatcatc cgcactcatc aaaacggtgg aagaatgggg aaaagaacga ggcatgactc
      541 acattgccgg tcctctcgga tttactgatt tcgatgcgga aggtatgtta gttgaaggat
      601 tcgaccagct tagtaccatg gctactatct acaaccaccc atactatcct gtacacatgg
      661 aaaagttagg cttcgagaaa gacgccgact gggtggaata caaaatctac ataccggatg
      721 ccattcccga caagcataaa cgtatctccg aactgatcca acgaaaatat aacctcaaga
      781 taaagaaata tacttccgga agaaaaatag ccaaagacta cggacagaag attttcgagc
      841 tgatgaatga agcatacagt cctctttatg gctattctcc gttgacacag cggcaaatcg
      901 accaatacgt gaaaatgtat ctgccgatcc ttgacttacg gatggttaca ctgattactg
      961 atgccaatga cgaactggtc tgtgtaggta tctccatgcc atctctcgcc gaagctttac
     1021 agaaatcaca cgggcgtctg ttgccactcg gatggttcta tctgttaaag gcactattta
     1081 tgaaacgccg tgccaaaatg cttgatctgc tactcgttgc agtgaaaccg gaatatcaaa
     1141 acaaaggtgt taacgctttg ttattttccg atttaattcc agtttatcaa aaattaggtt
     1201 ttatctttgc ggaaagcaac cccgaactgg aactgaacgg aaaagttcag gcacaatggg
     1261 attactttga gactcaacaa cataagcgcc gccgtgcgtt cattaaagaa attaataatt
     1321 aagaatgaag aatgaagaat ttggctgcgc tactacttaa tgccgcatgg caattcttca
     1381 ttctttattc ttcattcttc atttataaca gctatggaag agaacgaatt gatacctgta
     1441 gacaacaaca atgcagtaga gtacactgac gacaacatcc gtcacctaag tgacatggaa
     1501 catgtacgca cacgccccgg tatgtatatc ggaaggctgg gcgacggtgc acatgccgaa
     1561 gacggaatct atgtcctcct gaaagaagta attgacaaca gtattgacga gttcaaaatg
     1621 caagccggta agaaaatcga gattaccgtt gaagaaaacc tccgtgtcag cgtacgcgac
     1681 tacggacgag gcatcccgca gggaaaactc atcgaagccg tcagcatgct gaacaccggt
     1741 ggtaagtacg acagcaaggc atttaagaaa agtgtcggac taaacggtgt cggtgtgaaa
     1801 gccgtcaatg ccttgagctc ccgttttgag gtacgcagtt accgtgacgg taaagtacgt
     1861 accgctattt tctcgaaagg aaacctgctg agtgacaata cgcaagatac cgaagaggaa
     1921 aacggaactt acatcttctt cgaaccggac aatacattat tcctgaatta ctgtttcaag
     1981 cctgaattta ttgagacaat gctacgtaat tacacgtacc tcaataccgg gcttgccatt
     2041 atctataacg gacaccgtat cctgtcgcgt aatggtctgg tagacctttt gaacgacaat
     2101 atgacggcaa ccggacttta cccgatcatc cacctgaaag gggaagacat cgaaatcgcc
     2161 ttcacgcata ccggacaata cggagaagaa tattactcct tcgtcaacgg tcagcatacc
     2221 acccaaggag gtacacatca gagtgctttc aaggaacaca tcgcccgcac tatcaaggag
     2281 ttcttcaaca agaatatgga ctataccgac attcgtaacg gactggttgc tgccattgcc
     2341 gtcaatgtgg aagagcctat ctttgagagt cagacgaaaa cgaagctggg ttctaccaat
     2401 atggttcccg gcggagtgac agtcaataaa tatgtaggcg actttatcaa acaggaagtg
     2461 gacaacttct tgcacaaaaa tgcggatgta gccgaagcga tacaacaaaa gatccaagaa
     2521 tccgagaaag agcgtaaagc cattgcaggt gtaaccaaac ttgcccgtga acgtgcaaag
     2581 aaggcaaacc tgcacaaccg caaattgcgc gactgccgta ttcacctcaa cgacccgaaa
     2641 ggaaaaggac tggaagaaga ctcctgcatc tttatcaccg agggggactc tgcaagtggt
     2701 tccatcacca aaagccgtga tgtgaacacg caagcagtgt tcagtctacg tggtaaaccg
     2761 ctgaattctt tcgggttaac caagaaagtg gtctacgaga acgaagaatt taatctgctt
     2821 caggcagccc tgaatataga agatggcttg gacggactac gctacaacaa agtcatcgta
     2881 gcaaccgatg ccgatgtgga cggtatgcat atccgcctgc tgctaattac tttcttcctg
     2941 caattcttcc ctgaccttat aaaaaaaggc cacgtatata ttctgcaaac gcctttgttc
     3001 cgtgtacgca ataagaaaaa aacaatctat tgttatagtg aagaagagcg tgtcaatgca
     3061 attaacgaac taagcccgaa tccggagatc acgcgattta aaggtttagg agagatttca
     3121 ccggacgagt tcaagcattt catcggtaaa gacatgcgtc tggagcaagt ttctttacga
     3181 aagacggacg cagtgaaaga actacttgaa ttctacatgg gtaaaaatac catggaacga
     3241 cagaacttta ttatagataa tctggttata gaagaagatt tggcatcatg agaaaagcaa
     3301 tattcccggg tacttttgac cccttcacca tcggacatta ttcggtagtg gaacgtgcac
     3361 tcacctttat ggacgaaatc gtgataggaa tcggtatcaa tgagaacaag aatacatact
     3421 ttcccattga gaaaagagaa gaaatgattc gggaacttta caaggatgag cctcgtataa
     3481 aagtgatgtc ctacgactgt ctgaccattg attttgcgca ggaagtaggg gccaggttta
     3541 ttgtccgcgg tatccgtaca gtgaaagatt tcgagtatga agaaacaatt gcggacatca
     3601 accgcaaact ggcaggcatt gaaaccatcc tgctcttcac agaaccggaa ctgacttgcg
     3661 tcagctcaac gattgtacgc gaattattga cttataataa agatatcagc cagtttattc
     3721 ccaaaggaat gaggataagc tgagagttga gaatggagag ttgagaagga tgcaggcgta
     3781 tctgtgcccg gttgttaata ctcggctatt aatataaagt aagattatga ataagattaa
     3841 aatatacgtc cttttggctt gcctgtgggc agtatcagcc ttacaggccc aaaatttcgg
     3901 ttctgaagcc atgcgcaagc tacaaatggc agagttcgca atctcccatt tctatgtaga
     3961 caaagtagat gaagacaagt tggtggaaga agccatcatc aagatgctgg cacaactcga
     4021 cccacactct acctactcgg acgcagaaga agtgaagaaa atgaacgaac ctcttcaagg
     4081 taacttcgaa ggtattggag ttcagtttca gatgattgaa gataccctgt tagtagtgca
     4141 acccgtcagc aacggacctt ccgaaaaagt cggcatcctt gccggtgacc gtattgttgc
     4201 ggtcaatgac agcgccattg ccggagtgaa aatgagtacg gaagatatta tgaagcgtct
     4261 tcgtggtccg aaaggttcta aagtcaacct gactatcgtt cgtcgtggcg tacaagatcc
     4321 tttattgttc acagtgaaaa gagataaaat acctatcctt agcctcgatg cttcttacat
     4381 gattcagcct aaaacaggtt atatccgcat caaccgcttc ggagcaacca ctgccgaaga
     4441 attcaagaaa gcaatgacaa gccttcagaa acaaggtatg aaggacctga ttctcgacct
     4501 gcaaggaaac ggaggaggtt acctgaatgc agccatcgac cttgccaacg aattcctggg
     4561 gcaaaaagaa ttgattgtct acacggaagg acggactgcc aaacgcagtg atttctacgc
     4621 caaaggaaac ggagatttcc gtaatggacg ccttatcatc ctggtagatg aatatacggc
     4681 ttccgccagc gaaattgtca gcggtgcagt gcaggattgg gatagaggaa ttatcgtagg
     4741 acgccgttct ttcggcaaag gattggtgca acgtcctatc gacctgccgg acggttccat
     4801 gattcgtttg actattgcgc gctattatac tccatcggga cgttccatcc agaaaccgta
     4861 cgacagtact gtcgattaca acaaggacct gatagaacgt ttcaaccacg gtgaactgat
     4921 gaatgctgac agtattcact tccctgattc actgaaagca caaaccaaga agctaggacg
     4981 cactgtttat ggcggagggg gtatcatgcc ggattatttc gtacctatcg atactactct
     5041 ttatacggat tatcaccgta atctggtagc taaaggagcc gtgattaaat tcaccatgca
     5101 gtttatcgaa ggacaccgga aagagttgaa aaacaaatat aaaaaattcg aatcgtttga
     5161 tgaaaagttc gtagtcgatg atgatatgct cgctacttta aaagaaatag gagagaaaga
     5221 aggagtgaaa ttcaatgaag aacaatatca gaagtcgctt ccccttatca agacgcagct
     5281 taaagcactg atagcccgtg acctttggga tatgaacgaa tatttccagg taatgaatac
     5341 caccaatgag agtatacaaa aggcgctgga gatactgaat tcggatgagt atcagaagaa
     5401 gctgaaacag ggtattcagt aaacaatcat aagacatcat ttttcagttc ggtggacata
     5461 tatactcact atagtgaaaa aatatctatc ataagtatca ttcattttga tactcttctc
     5521 attatcaaag aaataagtat gatagatagc ttttaaaaaa ggtatctatc atacttttac
     5581 cagcaaaaac aggttatcta tcatctacaa aatagccgaa taaaggccct atatgcataa
     5641 gatagcttgt ttttgttgaa tagtttaatt ctcccctgcc ctatatctat cagatagaac
     5701 aaggcgtata aatacctcaa acaagcagag atagtttgct tttctccctg atatagttta
     5761 tctttgttac cgatatagtt cattcttcat ggccgtggcg aattcctacc acggccgtgg
     5821 aaagatacta ccacagccat gaagagatct ctccacggcc gtgggaaact aatgataaag
     5881 gcaccggaag acaactatcc ctatgcctta gtccaagaat aaaggcagga taacttataa
     5941 aagccgcttg ataacaaaca aacaacagct atataacacc ctccccctaa gtccgaagat
     6001 gatcgattag ctttgcaaca acagaaaaca atgtccttat aggcttgcaa cggtaaatta
     6061 aaggtacgta gtaatgtata aggcaaaaaa caaataaata atggcaatac aatttgaatt
     6121 gtacaagact ccccgtccca aggatgagga agacaaagaa gtgtatcacg cacgtgtagt
     6181 caacttccaa cacattgaca cagactattt ggcaaaagaa atccagatag caacttctct
     6241 aactgaaggg gatgtaaagt cagttctcga atccctaagt cattttatgg gggatcgtct
     6301 tcgggaagga caaagcgtcc atctggatgg catcggttat ttccagataa agctgaatag
     6361 tcaagaacct atcacttcgc ccaaactaaa agcgaatcag ataaaactca aagccaatat
     6421 cagctttaaa gcggatgcca aactaaaaag gtcagtcagt gttgttcatg tggagcgaag
     6481 taaactgaaa ccccattcgg ctgtcctttc aaatgacgag atagacaaat tgctgacaaa
     6541 ctacttcaag agcaaccctg tattaacccg tcgcgacttt caaggattgt gcggctttgc
     6601 ccctaccact gccgcacggc aaatcaaacg gctgaaagag gaggagaaga agttgaagaa
     6661 tatcaatact tattataatc cgatttatgt gccgatgcca ggatattatg gcaaggcgga
     6721 gataaagaca gatgaataaa aggaaccaac ataatacaga aataaaatga aatcagaaga
     6781 aataaaagag ctatttaagc agtttgagag cattgtttgc gaatacaaca aagtggaatg
     6841 ttggagtgcg agagaacttt atccattgtt aggatattct caatggcgta acttcctgtc
     6901 tatcatatag aaagcaaaag atacatgtaa aaatgccgga gaaaatattg cataccattt
     6961 tgctgacgtc agcaaaatgg ttatattagg ttcaggcgct gaaagagaag tagataacat
     7021 ctttctgacc cgttatgcct gctatctggt agcacaaaat ggagattctc gaaagcaaga
     7081 aattgccttt gctcaaaact actttgcaat acaaacgcgc cgtgcagaat tagtagagca
     7141 acgtttaata gaatatgaac gtgtccaagc acgtaccaaa ctagccgaga cagagaaact
     7201 tctctcgggt gttttatatg aaagaggagt tgacaatcaa ggattcgcca ttatacgttc
     7261 caaaggagat aaagcactgt ttcacatgga caccaaaatg ctaaaacgta aacttgacgt
     7321 acctgatagt cgaccattgg ctgattttct tccgaccatc agcataaaag ccaaagactt
     7381 tgccgcagaa atgacctctg tgaatgttca gcaaaaagac ctatacggac aaactgccat
     7441 tgaaaatgaa catgttgaca ataatgtcgc agtcagagat atgcttgttg gtagaggcat
     7501 atttcctgaa caaattcctg caaatgaaga tattgcggca ggggtatttc tctaaagaaa
     7561 aacgttttaa cacattcttt ataaatctga tttataataa aggaggggag gaacctatta
     7621 aaacagagcc tgttaggcag catctataaa aaggatttac aagcagcagt cgtgcaaact
     7681 aagtcattcc ctcaattctt cagtcattgt ttttagtaat gacctgctgt cacttaacgg
     7741 caaatccgta gctaaatccc aactcatcat acctttcagc ttctgttcct ttgcataacg
     7801 ggttttgata cgaatgttat cctgaccgtc aaacacataa gtatctccct gatagatcac
     7861 ttcattctgt gcaggactcg taaccaatcc attctgtaca aaattgaaat aagcctctgt
     7921 cttctttgaa ttatctttgg tcaccccata aaaaggaact cctgccacca gtttttcctt
     7981 cggaatacca tactccaata ccatctgtat atccgaacaa tatttctcta tcggaaagcg
     8041 aaccggtgaa ggaccatagc actgaagtga aataaaatca actgcttcaa tagcttcctt
     8101 actaatctta taacaaacag gatgcagaga tacactgaaa agatacttgt ctcccaacac
     8161 ttcacgcatc ttcaggatag ccaaactata atctttatat tctttctcat tttccgccca
     8221 ctcaaaatca agatcaatgc catccagttt attcttttcc agtacagtct ttatgttctt
     8281 tgcaaacgtc gtacgagcgg cctcatcggc caccatcgct ttccattcgc cactggaagc
     8341 acccaaacgt attttcactt ttgtaccttt tacttttgca cgaaccgatt taatcaaacc
     8401 ttcccaagtg gtcacccctt ttccctgaaa tacacgtgga ttctcaaatg acaatgatcc
     8461 gtctttatta ggatgaacat tcaagaaaat aaggtcgtta cttgcccgca agctttctgt
     8521 agaaatacga ccacggttgt aaaaattacc ccgcacataa gaactgacca tatagtcttg
     8581 ttgtgcaaac aatgataatc caacaaacac aaaaaggaag aatacaattt ttcttagcat
     8641 tagcataatg attgataatt aaaacgttta gatcgcaaaa atacgcatat caaaagcaaa
     8701 cagatgttca aaaacaacta taatacttcc aaaaatcaac ataaagtttt ctattcagaa
     8761 atttaaaaca gataaatatt gaattcttta acatcatcca aagggataag aataatattt
     8821 gcaggtttct actaaaacat aaataaaaga aagagttcca ttttccgcaa aaaaagccta
     8881 tctttgttcc gttaagataa taaatcacgc ataaaactca tgccaggaga ttcattttgc
     8941 atacaatata ccaactgtac gggatgtcca aaaaatgttg agaatatcct tgtatataga
     9001 aacttaccta aaggagagca tatccccaag gataagtgta cgcagaattg tatgcttttt
     9061 atgataaagg gcgaattact tatcaatagc gaagagcatc ccggaataac gttacgcgag
     9121 agacaaattg ttttgcaagc tattggctcc aaggtcgaaa tactggcact gacagatgtt
     9181 gaatacgttg tctactggtt caacgaactg cctttgcttt gcgaagaccg atatagggaa
     9241 atgatggaac aggcggaagc tcctttgacc tacactccac tgattatgag cgaaaggctt
     9301 taccaccttg tcaccagtat gcccgaattc ctcgctgagg aaaacccttg cagcaagtat
     9361 atcgacttaa aatgcaaaga actggttttc ttgattacca acttttatcc gctgccccaa
     9421 ctgagttcat tcttctatcc gatcagcact tatacggaaa gtttccacta tttcgtcatg
     9481 cagaattaca gcaaggtgaa gaacgtggaa gaatttgcgc atctgggagg atatacgacc
     9541 actactttcc gccgactatt caaaaacctc tatggtgtgc ccgtatacga atggatactg
     9601 gaaaagaaac gggaaggaat cctggaagac ctacagcaca ccaaaatgcg aatcactgaa
     9661 atctgtaaca gatacggatt cgactccctg tcgcatttcg cccacttttg taaagactct
     9721 ttcggagata ccccacgcgc tttacgcaag aaagcagccg gcggtgagaa aatcgggaaa
     9781 gtacaataaa cagcctcatc ctactaatgt gccaatcagt tgcaccatgc gcgcatactg
     9841 gctggcatat tgatacatta gcgcattgat tcattattaa agaattattt ctttaattcc
     9901 ttgctcaatc aatctatttc ccctattttt gcagtctgta agaggtgtaa aacgtcgaaa
     9961 ttttagttct aacaattaaa taatttaaat tcaatcattt atgtggttaa gtaattcatc
    10021 tgtaggaagg aaagtggtga tgagcgttac cggtatcgcc cttgtcctgt ttctaacatt
    10081 tcacatggcg atgaacttgg ttgcaatcat ctcggctgat ggttacaaca tgatttgtga
    10141 gttcctggga gcaaactggt atgcgttagt ggctaccgca ggactagccg ctctttttgt
    10201 gattcacatc atctacgcat tctggctgac aatgcagaat cgcaaagcgc gtggtagcga
    10261 acgctatgca gtggttgaca aaccaaaaac tgtagaatgg gcatctcaaa acatgttggt
    10321 gctgggtctg atcgttatcg taggtcttgg tttgcacctc ttcaacttct gggcaaaaat
    10381 gcagttgccg gaactgatgc acaacatggg catgcacgct gatacactga cgctggctta
    10441 tgccgctaac ggtgcttatc acatccagca gactttctct agcccggttt acgtagttct
    10501 ttacctcgtt tggctgtttg ctttgtggtt ccacctgact cacggtttct ggagctctat
    10561 gcaatcactg ggatggaaca acaaagtatg gatcaatcgt tggaaatgta tttctaacat
    10621 ctattctacg attgttgtac tcggtttcgc actggtagta gtggtattct tcgtgaaaac
    10681 actgatttgt ggcggtgctt gctaaatagt aaattgtaaa tgattaaatt gtaaataata
    10741 ttatgatcaa gatagattca aaaattccag aaggcccggt ggctgagaaa tggaccaact
    10801 ataaagctca ccagaaattg gtgaaccccg ctaataaacg tcgtttggac atcatcgttg
    10861 tgggtacggg tctggcaggt gcttctgccg ctgcttcact tggtgaaatg ggtttcagag
    10921 tattcaattt ctgtattcag gattctcccc gtcgtgcaca ctctatcgct gcacagggtg
    10981 gtatcaatgc tgcaaagaat tatcaaaatg acggtgactc cgtttaccgt ctgttctacg
    11041 atactgtaaa aggtggcgac tatcgtgccc gtgaagctaa cgtatatcgt ctggctgaag
    11101 tgtctaacgc tatcatcgac caatgtgtag cgcaaggtgt tcctttcgct cgcgaatatg
    11161 gcggtacact ggataaccgt tctttcggtg gcgcacaggt atcccgtact ttctacgcta
    11221 aaggccagac tggtcagcag ttgctgctgg gtgcttactc tgcattgagc cgtcaggtaa
    11281 acgtaggtac tgttaaactg tatacccgct acgaaatgca ggatgttgtc atcgttgacg
    11341 gacgtgcccg cggtatcatc gcaaaaaatc ttgtaacagg cgaattggaa cgtttcgccg
    11401 ctcacgctgt agtaatcgct actggtggtt atggtaacgc ttacttcctg tctactaacg
    11461 ctatgggttg taactgtaca gctgctatct cttgctaccg caagggtgct gtattcgcaa
    11521 atcctgcata cgttcagatt cacccgactt gtattccggt acatggcgac aagcagtcta
    11581 agctgacttt gatgtctgaa tctctccgta acgacggtcg tatctgggtt ccgaagaaga
    11641 aagaagatgc tgtaaaactc cagaaaggcg aaatcaaagg aagtgatatt ccggaagaag
    11701 accgcgacta ttatttggaa cgccgctatc cggcattcgg taacctggtt ccgcgtgacg
    11761 ttgccagccg tgccgctaaa gaacgttgcg acgctggttt cggtgtaaac aacacaggtt
    11821 tggccgtatt cctcgacttc tctgaagcta tcaaccgttt gggtatcgac gttgttcttc
    11881 aacgttatgg taacctcttc gatatgtacg aagaaatcac tgacgttaat ccgggcgaac
    11941 tggctaaaga aatcagtggt gtgaaatatt ataacccgat gatgatttat ccggctatcc
    12001 actatacaat gggtggtatc tgggtagact acgaactgca aaccactatc aagggtctgt
    12061 tcgctatcgg tgaatgtaac ttctccgacc acggtgcaaa ccgcctcggt gcttctgcat
    12121 tgatgcaagg tttggctgac ggttacttcg tattgcctta cactatccag aactatctgg
    12181 cagaccagat cactgttcct cgtttctcta ccgatcttcc tgaattcgct gaagctgaaa
    12241 aagctgttca agctaagatc gacaagttca tgagcatcca gggtaaagaa tctgttgatt
    12301 ctatccacaa gaaactgggt catgtcatgt gggaatatgt aggtatggga cgtacggcag
    12361 aaggcctgaa gaaaggtatc gccgaactga aagaaatccg caaggaattc gaaacgaact
    12421 tgtttatccc cggttctaag gaaggtatga acgtagagct tgacaaagca atccgtctgt
    12481 acgacttcat cactatgggt gagcttgttg cttacgacgc attgaaccgt aacgaaagtt
    12541 gtggtggtca cttccgtgaa gaataccaga ctgaagaagg agaagcaaaa cgtgatgacg
    12601 aaaacttctt ctatgtagca tgctgggaat atcaaggtga tgatgaaaag gctccggtat
    12661 tgcacaaaga accgctggta tacgaagcta tcaaggttca gactcgtaac tacaagagct
    12721 aatcggtgaa gttaaacatt taaaagaatt agaagaaaat ggataaaaat atatcattta
    12781 cactgaaggt atggcgccaa gctggtccga aagctaaagg tgcttttgaa acctaccaaa
    12841 tgaaagatat ccccggtgat acttccttcc tcgaaatgct ggatattctg aacgaacagc
    12901 tcatcagcga aagaaaagaa ccggttgtat tcgaccacga ctgccgcgaa ggtatctgcg
    12961 gtatgtgttc tctttacatc aacggacacc cgcacggtcc tgcaacaggt gctactactt
    13021 gccagatcta tatgcgtcgt ttcaacgacg gtgacaccat cactgttgaa ccttggcgct
    13081 cggctggttt ccctgtcatc aaagacttga tggtagaccg tactgcatac gacaagatta
    13141 tgcaagctgg tggttatgta agcgtacgca caggtgctcc gcaggatgct aacgctatcc
    13201 tgatcgcgaa acctatcgct gacgaagcta tggatgctgc ttcttgtatc ggttgcggtg
    13261 cttgtgtagc tgcatgtaag aatggttctg ctatgttgtt cgtttctgcc aaagtcagcc
    13321 agttgaactt gctgccgcaa ggtaaaccag aagctttgcg tcgtgcaaaa gctatgttgt
    13381 caaagatgga tgaactggga ttcggtaact gtacaaacac tcgtgcttgt gaagctgaat
    13441 gtccgaagaa tatttctatc agcaacatcg ctcgcttgaa ccgcgacttc atcatcgcaa
    13501 aattaaaaga ctagaaattg ctagatttca atagcgagag cttaatttga ttaatgacag
    13561 aatcccctgc cggctagtcc gacaggggat ttctttatgt atgagtagac cacaattatt
    13621 attaatacgg atcagtaaca tgaactttta attcataagt ttcaccgatt tcaccttata
    13681 gccagaactg ttatgaatga gagaattacg ggtgaaagcg aggattgaaa taaggtaaaa
    13741 tcattcgtta ccgctttcac ctgtcttatt aaaatatccc ttgagctaaa acaattatca
    13801 ttatagctaa tccggatatg cttatagcaa atccgctttc aggtgttaat gagtgaactg
    13861 tgcggatgta gtactttggc cgccaggtct taacacctta gttctcatgt gttaatactt
    13921 gagttgttgc atctatatat ccagcatctt ggagctatat atccaacacc ttggatctat
    13981 atgtccaaca gtcggtatga ataaactcaa taggtgaaac cgggaaggtt cagtttcgcc
    14041 tgaatttctc ccttgctttc acccgctgtt accttattca tcggcattta gagaattggg
    14101 tgaaaccggt gaaccgcagt tattttacat agttgcattt atgaaatgtc ttgcctacgt
    14161 aaattacgtg gagaggcacc aaaagatttc ttgcagaaat tagaaaaatg gggtaaagat
    14221 tcaaaaccat atttatagca tatctccgag atgctacatt tagagttgtt caagtcgtcc
    14281 agaatgccct ctttacgtct cgccagcatc cattcataaa caggttcatg aaagacgtta
    14341 ttgaagatac gacggaatgt actaagggta tatccaccca attgtgccag ttcttccact
    14401 gtctttactt tcttatagtt ttgaataacg aagtattgga aactgtttac atatttagag
    14461 agtggatgca ccaagctcga aagatcataa tcggaataat agtatcccaa tacaaacgcc
    14521 aattcttttc gtttcagaga tagcaaatcc cgacagactt tatctccttt caaataagtg
    14581 atagacccat tgaggaaata ttgcagttct ggaattattt ttaatggagt ataaataagt
    14641 ggaggagata cttccttcat gatatgattg aaacggaaat cacaaaacag ttcgggctga
    14701 ataaaacgat aataaatgca ctcacattca gtcatagcaa gcatctcaaa catagaacca
    14761 atggcctgaa ggataaattc accttcctta agcattgtcc ccgcatattc cttactattg
    14821 accagtattt ctcccttcat caaaaaaagg ataagatttt cttcacactt ttgagccggt
    14881 ttatgaaaac cacgctgata aatcacatga gtaatggcat tactcaccgc ttttggacat
    14941 atttgacaat cccaggttcc ttgacaaata gatggcatac gctgactgtg tttgtttttg
    15001 tttatgctgc cagcaaaaat atatgaaatc tttcatattg ccataaaaaa aaagagaaaa
    15061 gtgaaaaaga ggttagataa gagatactca cttgaacatc ttgaagccta gtttttctga
    15121 tttgaaaaac taggcttcaa gattcttaaa ttaagatatg ttcaagcatt ctacattcct
    15181 atgcaactag ttattacact gcaggagcca caggatcttt ttcctgatta tcctcatcag
    15241 cccatttatc tacatcagta acatcccacc caatagttgc agcatcattt gttagagaca
    15301 atgtataacg tatactttta cctactcccc atatagcatc cttcaaatca acttctttag
    15361 gagtagctcc tgttgtatac acttcatcac cattcttatc agtaacatta tagcttacta
    15421 acattttcct tgttgtcaat gtttgaggca ataacattaa agattcagta ccaatatttt
    15481 tactcgttgt tccctgaact gcattatttg tagtagtaat atcatccaaa ggataaatat
    15541 atgttgcaga tccctccaaa gaagtccaaa cattatcagc atatttatat gttcctttat
    15601 cattcactcc atttatttct attttagata cagtatatgt taacttatca tcaagctttg
    15661 attttatagc aaattgaatc tgtgtaagta catgtgagaa cgtgaaatta acactcaaat
    15721 ctgcttttgt cttatccgta actttagcca caagcaaatc ttcctgatta ggtgccgtat
    15781 cagcaatttg ataattaacc aatgtaggat actgatctgt atcagtagct gttagtgtta
    15841 atgaccgaga agaagaatat gcaaaaaatt ggatttttcc ctgagaaggc cagtaatatg
    15901 cattattaga tgtccattta ttgtcacccg aattccatga aacaggttca ttctccatta
    15961 tcgacttatt taaagttcca gttccaacaa cagcatcacc tgtattatat gcataaacat
    16021 gaaaaccttg agtttttaat tcatcgagct tcatctccgt ggctcttgta gcattactga
    16081 ctatgctctc aaagtttatg actgcattct gtccagcatt ctcaaattct tcattctgtg
    16141 agcaacccgt aattgccaaa gcagctgtaa ctgccaataa aatcttcttc ataactgtat
    16201 ttttttaagt ttataatatt gttatatttt gtttatagct tctatttcaa ttcacgggta
    16261 actcaacatt atcttcgggt ccccatccat caacattgcc gcccattcct ccacctccat
    16321 caggattcgg tggtgtttcc ggcttatcaa cctcaatctt atcatcaggc ggtaactcaa
    16381 tctccggtgg tggggttggt tttccatctt cccctgttcc agcattttca agtgtaccta
    16441 ttatttcagt aacatcaatt gttgcttcct gaactgtatt atctgttttg ataaatttca
    16501 atattaatat tatagcatct ttctcactag aagtttctct ctctgatgtt gacattcgcg
    16561 tcggcattgt catttccttt acttgtttga aagcggtgaa agatgccgtt accttattgt
    16621 ctcccttcct tacctcaaag tagataggtt gtgagctaca tactccacga cctttgccta
    16681 tacagtaaca atcggataat ccatcaatgc ttcctaccac tgttgcaaca tactccaaac
    16741 ctttagcctc tactgcaaaa gaatatttct tcaccacaga ttccaacttc cagtctaagc
    16801 gaagcacttc ttcactcttc tctatttcca gctcatctat attcaacaca tacaatgaat
    16861 ccggtgacca aaccatcttt tccgttcctt caatccctaa accattacag tttcccgtat
    16921 aggcttctat cgtttcataa gactcttcgc ccctgattcg tatagattcc gtgttatagt
    16981 tgtagactac taccgaatac ctccccggag gaactttcat ttctccacct cgtaccgaaa
    17041 ggtatttatc tactttcctg ccatctccgt tcttcggata aaaaatcacc cgaactccct
    17101 ccggcagttg atctgtcact ccatcccaat ccagctttat atctacccca cttacgggat
    17161 aatcatccaa tatatcgcga cggctacatc cagttagcat cagcagcgag gacaaaagca
    17221 caagaaaccc atatcttgta tttcgcatta cgccctccta tttctttgtt gttatcaacc
    17281 ataccaaaga aactttcgcc ttggtaggac caataaagtt ataacgccca ctatttgtcc
    17341 atataatatc tccctcataa ggagtatatt ttttatattc tgttgtcaaa taccctatgc
    17401 caagactgaa ttcaagggaa aaatgccgtg ccaattgccg tgcatatcca taagtcactc
    17461 ccgcagctcc gtaatactta ccttgatagc cgtctccacg cagctggaag tcatatatcc
    17521 cgccttcagc ataaagtccg ataaaatgtc cggtcaatcg gtcgcgtttc tgacggtttc
    17581 ccagccaaca acgtccttcc atccctcccg aaaggagctg atagcagaaa tcatgtttgc
    17641 tattcagcca ccacggacat ttatattcag tattcaaaga ccacctcttg cctatcggaa
    17701 tttccacttc tatatttggc gccaatgcca aatcatataa cagattattc ttcactgcaa
    17761 gtacagtttg gcttttcacc ggcccttctg cctccgatat atcgacctca caggcctgtt
    17821 tttcttcact ttctcccaca ggcttatcag gttgatcttt cggaagcgcc tcttcctgct
    17881 ttgaaacaaa caacccggag acagaagata ccggttcaaa agcctcttta cctaatttcg
    17941 aagtttctcc gacaatcgta ataaccgatc ttcgcagctc cggaaagata ttgcgaacaa
    18001 tgtatcggta agcaattccc cgattcaatt ttcgcaacag ttgtttccgt ttattgacat
    18061 cattcttatg ataatcaatc aatatcagca cttcttcccg atctggcaag ttggagtcgg
    18121 atgccaccaa cttacgaaac tccgaccaat cctctccctc tgaaaaaaaa tgaatcttat
    18181 caacactaac atccgaatta taccgttgta agaattcctt tatcgaatca tttctccgag
    18241 cagccaaact tctattataa gattcatcac catcaggaga aacaaaagtt ttcacattca
    18301 gcgctgttat atatttcgta ttcaaatttc cgagaagcaa agaatctaaa attgtaattg
    18361 cctgattatt atctttataa ctaagatcca ccttcgcttc attcgcatca aaatatatca
    18421 ctgcccgccg gattgtatca ttcgcaacag cgaaaaatgg aatcgaagca tacccacttt
    18481 ctggaaggct taataaagcc ataagaatag tcaatatata gataccatgt ttcattgtcg
    18541 ttcgtttctg atgacaaata tagaagttag aaaacaaatc gaatcatact tttagaacaa
    18601 aaacaaaggc atgaaaggtt ctgtgaaacg attggaacga ttttgcaagt ttgggtaact
    18661 aaagtcagtc ataaataaaa aaagatacac agattatcga ctataaatcg attctctgtg
    18721 tatctactag tcaaaagctt gtcttgtcag tcaacaacta ttgggaaaac tatagtttcg
    18781 acctatttgt agataatcag tttaggttta tggcaagagt tgtagtggtc atcaagtatt
    18841 gccccatttg agaaaatgat gtgctcatcc ttgaatgtac catatccttc gtgagcgtga
    18901 ccgaacaaat gataatgtgg ctttacctcg taaaccttgt ttcgaagtaa tacatttccc
    18961 cagtgaattc ctgctgattc atcaagtatc atgataggag gttcatgggt aatgagcacg
    19021 tcaacatcat ttgatatcaa agtctcagga tggttatatg ccaaaccaaa gaacttaata
    19081 ccatcaatct cacattcaca atcttgaagg aagtatacat tgttaggcaa atcttcaatg
    19141 ccttcagcct cccaaaggca gaggtcatga ttaccagtta tgaagatttt gtgaggatag
    19201 gataattcga tgaaccagtt gagaaagtta agcacttctc cctctgtacc attgtccgta
    19261 aaatcgccac agtgtacaat gacatcagca gctggaagat cggtcaactg ccgatgctga
    19321 ttatgtgtat cagaaatttg aagtattttc attttacaga aatatgaatg tcatgtatgt
    19381 caacatcacc ttcgtcgaat ataaagtatg aagaaattcc actaatgcta tcatatcgtg
    19441 agttctcatc tttatgtata ggtatgactc caatacgagg atgaacagtt tgacagactt
    19501 cttttaatgt ttcaacatca gcgtgtccac ttgtgtgaac accatccatt gttccatcta
    19561 atattctatc gccaaacaga ttacggatat ttataacatc gctgtttgtg tagtctttac
    19621 cctcttttgc atagccactc cacatagaat atatcaacca cggtttttca tcattatata
    19681 tatcgagcat tcccttaagc aaatagccac tactcattcg aattggcatt aagaaccctt
    19741 ccttctgtag cttgtttcta acattgacag ttctataatt gattagcttg aaagcattaa
    19801 actggaataa atcagatttg catcctgcat atttcgtgaa tacattaagg accctatttt
    19861 gatactcatc aactaagaat atacgtccag tctttttaca cgccgcatgg aatgttgcaa
    19921 gccggtcaag gtcagttgac gaacacaagg caaagacata cttgtgttca cgcaatgcct
    19981 ttataatatt cttctgtatt tcgctctctg aaatcacaca ttcttgactt cttcctaaca
    20041 ttgttccttc tgttataagt atgtcaactt ctcccacatt cttcttcaaa gtaggaaaaa
    20101 gacctttgcc aatatagcca tgtctgcgaa aatctcctgt gtgcaatatc ttctttccct
    20161 cacattctat taagaacata tatgcatcaa aagcagaatg actaacaaaa tagggagtaa
    20221 cgaaaatctt ccctttctta ctgacatcaa tacgttttgc cgcacaatag gtttccatac
    20281 gctctattgc ttcaatctgt ttggagtaat ctccgtgccc cctcaaagcg tcatatttgc
    20341 agagcataac ttcttttgct cctactccta tatattgaag gacatttgtt ggtatcagat
    20401 ggtgcaaacc aacatgatca ctatgataat gtgtatagaa tacggcatca gcatttccta
    20461 tgattgattt tacttgttct tctgtcagtt cttctttttt gcaaccagga agattgctac
    20521 cgaagtctat aagaatttta caattctcag tcgatatttc tgtaatacaa ccacctatct
    20581 ggtcagcccc acgatgaata ataagattca ttctgcttct aatttttctg atgtaacgag
    20641 agtaccctcc tcgcgtatgt atgtgtatgc tttcatttcc ggcaaaaata aatcacgaat
    20701 aaatctatat ctttcgcaga ttgtttcaga tagtctattg tcttctccta caattacaca
    20761 cggtattatt cttccggaaa gctttaatgg tattttattt ttgtaactgg aatcgataag
    20821 tccataatct attttttgct cgatcattgc ttttattcgt tggtacaact tatcatcttc
    20881 tctagctaat ttttgaaact gtagatagta atatgaagtt tgaatgggcg acaatgcagt
    20941 cttagcagga tcattttgtt taagttccat tatcaatata tctccattag tatttagacc
    21001 aaggaagtca aattcaccat actcaggttt tatttcttca gggagtgttc cattgtacgt
    21061 ctttcttaat tgttcaattt tcaatgtttg ttggtctacg atttccttat tccattcatc
    21121 ttttatgtct tttgttttaa aaccgataac tagttccttg tcaaaaagaa taaaatcatc
    21181 agtatcttta acttcgaacg tataacgacg tcctattaat gtctgataaa atccttcatt
    21241 gcgaactcct tttgtatcct catagtatct tttgaatttt tccgtggaag cgattttcgt
    21301 taaatatgtg tcaaactgat ccggtgttgg atttctaaaa aaatctggtt gcattaattc
    21361 tttgtaagcc tcggctacat cacataattc attaacttta cccgaatgac tacgaaaggt
    21421 tagtatacgt ccagtacctc tatatataga aaaccaagaa cgattagttt taggatcatt
    21481 tccagtctgg aaatctaaac aattatgtga tttaacataa ctgatgatcc aaggaaaccg
    21541 ctcgtttatt tgggttagca acttttcatc cattttccta tcgtaatagg ttgttcttat
    21601 tgtgtaatta ttaaccattt tcaatttctc cattttagag tttataactg tgtattattg
    21661 atctctgcta agactctgca cgccattatt tttctattta tatctattta tggcagcaaa
    21721 aagtcgtttt ctaatttctt cacgcagccc tattggttcc ataacttcga tcttttcccc
    21781 catagcaagt aactgacttg ttagctctgg agttaagcaa agttggtatt caaagtcgct
    21841 gtactctttg tgttctgtcc ttatctcttg ttgagagaaa tgcagtggca gagaacgcat
    21901 atactccaca tgaacaccga atgcccgaac aactactttc tgtggcttca atttgtcatt
    21961 gacaaatatg ccaactgtat gagcataata ttcttctgca tcaaaatcat tggggagtat
    22021 aaatgagtca tctgtcaatt ccatttccaa agtacgatca agggcaatat tccttattcc
    22081 ttcctgctct ttgagataac cgactacata ccaacgctga tggtaaacct tcatagcgta
    22141 tggctgcaag tgaaatattg actgatgacc attgaaaggt ttataatcaa tcttcaattc
    22201 cttttttcgt tgcattgcat ctatgactgt ttggagatat tcagttcctt caggaatttc
    22261 ctcaaacaaa attcgatctt tcatgttgcg ccctgcttct atcatattag acacagtgaa
    22321 ggagttaagc aaccactgac gagtcttgtc atttttcagt tgactggaag aagaaatata
    22381 atactcatag ctggaggtat cacattcgac ctctacacca aaaagttctg caatagcttc
    22441 tctatgcatg tggaatgtac gtaatgcaag cggtctacca tcaccgagac aactatcttt
    22501 ccatcgacag cttatctctt caaaagttaa tctgcgatgc tgaagcagcg tgttgagcaa
    22561 ccagatatag cggttgaagg ttttacttat cattttctaa acttccgtga ttttcaaaat
    22621 attattacta ttttctatta ttcaattgct taaacccttt ttgtatatct catctaattg
    22681 tttttcctac tttagatatc ttgatagcat gttttatagg gtagaattca taatcttatt
    22741 tagtacaaag ttaacttttt tgtatgcaaa aatactgcat accacctaaa tatattaatt
    22801 tatagcaatt ttttttatgt gtgcaacgtt tctgcatact tcaccattat ttttgcacac
    22861 tcattttaac attctattcg tcatggcata caaaaaaaat ccaaagaaaa aagatgctct
    22921 caatataaag agagctgtag aatctctgcg tttccaaatt gattggggtt taaaactact
    22981 tggcgcaaag aaaggagatc tatttcatca attagcaaaa gtagaggttg atctcatctc
    23041 agagctcaac ctcacccaag atattcttgc tatcaagagc ctcgtggatg gagtgaaaca
    23101 gaatttacag atagaaccta cacccgaaag tggagacttc acccatagta tcgttgctct
    23161 cgctcttggc attgcctcaa ttagccacct taacaacata agtttaccag aatcatggag
    23221 agaccagata gagaaaaagt tgcttacaat ctattatcca gaaaagctgc gtaacaaaat
    23281 cgtagattgg gcaaaagcga acggttacag cacctccaat taccttggcc gtccaatcgt
    23341 gaaattcaac caattatact taattataga aagaacaaga taaatcagcc ttttttgctc
    23401 tgatcttcgc attttttaca aaatacgctc attccatatt aaacattcca ttctactacc
    23461 gataaatatc catccagtta caacaaataa gaactttcat gatcatcttt acat
//
