## Wed Jul 10 06:36:32 2024
## emapper-2.1.12
## /d223NFS/m128030022/anaconda3/envs/eggnog/bin/emapper.py -i /d223NFS/m128030014/NGP/gene_list/prokka_results/GCA_905203575.1/GCA_905203575.1.faa --temp_dir /d223NFS/m128030022/NGPs/NGPs_new/databases/NGPs_DB/NGPs_db/GCA_905203575.1/2.eggNOGmapper --output_dir /d223NFS/m128030022/NGPs/NGPs_new/databases/NGPs_DB/NGPs_db/GCA_905203575.1/2.eggNOGmapper --output eggNOG_out --override --cpu 20 -m diamond --sensmode fast
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
HALNLLBL_00001	1280671.AUJH01000021_gene3773	1.07e-13	72.4	2EFW8@1|root,339NG@2|Bacteria,1VI6U@1239|Firmicutes,24UK7@186801|Clostridia,4C05M@830|Butyrivibrio	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_00002	471875.RUMLAC_00869	3.85e-90	268.0	COG0602@1|root,COG0602@2|Bacteria,1V1HG@1239|Firmicutes,24HIJ@186801|Clostridia,3WIIU@541000|Ruminococcaceae	186801|Clostridia	C	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	nrdG	-	1.97.1.4	ko:K04068	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
HALNLLBL_00003	246199.CUS_7762	0.0	1220.0	COG1327@1|root,COG1328@1|root,COG1327@2|Bacteria,COG1328@2|Bacteria,1TR9K@1239|Firmicutes,247WF@186801|Clostridia,3WHPK@541000|Ruminococcaceae	186801|Clostridia	F	Ribonucleoside-triphosphate reductase	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
HALNLLBL_00004	1410617.JHXH01000009_gene1645	2.63e-43	151.0	COG0664@1|root,COG0664@2|Bacteria,1V8K7@1239|Firmicutes,24JZ5@186801|Clostridia,3WPPC@541000|Ruminococcaceae	186801|Clostridia	K	COG COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
HALNLLBL_00005	411467.BACCAP_02217	2.04e-89	272.0	COG1349@1|root,COG1349@2|Bacteria,1TSF8@1239|Firmicutes,2498W@186801|Clostridia,269MK@186813|unclassified Clostridiales	186801|Clostridia	K	DeoR C terminal sensor domain	fruR	-	-	ko:K03436	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
HALNLLBL_00006	1280685.AUKC01000005_gene2039	4.23e-126	369.0	COG1105@1|root,COG1105@2|Bacteria,1TQ36@1239|Firmicutes,249RK@186801|Clostridia,4BW6I@830|Butyrivibrio	186801|Clostridia	G	Phosphomethylpyrimidine kinase	pfkB	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
HALNLLBL_00007	1384065.JAGS01000001_gene468	1.83e-266	752.0	COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,248V6@186801|Clostridia,3WHCI@541000|Ruminococcaceae	186801|Clostridia	G	PTS system	fruA	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
HALNLLBL_00008	1042156.CXIVA_17750	5.87e-35	121.0	COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,24QIP@186801|Clostridia,36KJQ@31979|Clostridiaceae	186801|Clostridia	G	HPr family	ptsH	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
HALNLLBL_00009	1280679.ATVX01000016_gene3315	3.5e-239	677.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,4BXQH@830|Butyrivibrio	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
HALNLLBL_00010	1235793.C809_02170	5.05e-74	230.0	2DXV6@1|root,32V45@2|Bacteria,1VBYR@1239|Firmicutes,24P8R@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_00011	706433.HMPREF9430_00922	9.72e-16	70.5	2C3TZ@1|root,33DSH@2|Bacteria,1VM6H@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_00012	1121296.JONJ01000005_gene1219	3.44e-93	278.0	COG1636@1|root,COG1636@2|Bacteria,1TT7H@1239|Firmicutes,248EA@186801|Clostridia,21YQV@1506553|Lachnoclostridium	186801|Clostridia	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queH	-	1.17.99.6	ko:K09765	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF208
HALNLLBL_00013	428125.CLOLEP_01169	1.3e-58	191.0	COG0546@1|root,COG0546@2|Bacteria,1V3YI@1239|Firmicutes,24HZR@186801|Clostridia,3WJQC@541000|Ruminococcaceae	186801|Clostridia	S	phosphoglycolate phosphatase, bacterial	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
HALNLLBL_00014	556261.HMPREF0240_03532	8.7e-46	156.0	COG1878@1|root,COG1878@2|Bacteria,1VDFH@1239|Firmicutes,25CZC@186801|Clostridia	186801|Clostridia	S	Putative cyclase	-	-	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
HALNLLBL_00016	1160721.RBI_I02050	8.3e-310	847.0	COG0423@1|root,COG0423@2|Bacteria,1TP94@1239|Firmicutes,248FB@186801|Clostridia,3WGTU@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
HALNLLBL_00017	877411.JMMA01000002_gene1429	3.56e-206	579.0	COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,24969@186801|Clostridia,3WGFU@541000|Ruminococcaceae	186801|Clostridia	H	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	dapL	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
HALNLLBL_00018	500632.CLONEX_00534	2.23e-293	812.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,2482E@186801|Clostridia	186801|Clostridia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS01075	CTP_synth_N,GATase
HALNLLBL_00019	428125.CLOLEP_02638	0.0	2135.0	COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,2498I@186801|Clostridia,3WG9X@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,DAP_epimerase,MGS
HALNLLBL_00020	1160721.RBI_II00014	9.3e-185	522.0	COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,247Q8@186801|Clostridia,3WH1G@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
HALNLLBL_00021	445973.CLOBAR_02074	1.79e-34	127.0	COG3707@1|root,COG3707@2|Bacteria,1V9FH@1239|Firmicutes,24JZU@186801|Clostridia	186801|Clostridia	T	ANTAR domain protein	-	-	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR,Response_reg
HALNLLBL_00022	397287.C807_02916	9.43e-265	742.0	COG0004@1|root,COG0347@1|root,COG0004@2|Bacteria,COG0347@2|Bacteria,1TQYG@1239|Firmicutes,247W1@186801|Clostridia,27ITM@186928|unclassified Lachnospiraceae	186801|Clostridia	EP	Ammonium Transporter Family	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp,P-II
HALNLLBL_00023	537013.CLOSTMETH_00827	0.0	984.0	COG3968@1|root,COG3968@2|Bacteria,1UHUF@1239|Firmicutes,2481B@186801|Clostridia,3WHCK@541000|Ruminococcaceae	186801|Clostridia	S	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
HALNLLBL_00024	1160721.RBI_II00513	0.0	2654.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1TQ0B@1239|Firmicutes,248IB@186801|Clostridia,3WHE2@541000|Ruminococcaceae	186801|Clostridia	E	glutamate synthase	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
HALNLLBL_00025	1160721.RBI_II00514	6.68e-306	840.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,2490X@186801|Clostridia,3WGBX@541000|Ruminococcaceae	186801|Clostridia	C	glutamate synthase	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
HALNLLBL_00026	1235835.C814_03363	8.45e-170	487.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia,3WHD5@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	tRNA_U5-meth_tr
HALNLLBL_00030	1336241.JAEB01000024_gene1156	2.96e-287	811.0	COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,25VCN@186806|Eubacteriaceae	186801|Clostridia	L	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N,SNF2_assoc,SWIM
HALNLLBL_00031	397288.C806_03706	8.33e-73	224.0	2BZS9@1|root,2Z92C@2|Bacteria,1UYYZ@1239|Firmicutes,25CHG@186801|Clostridia,27M3R@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_00032	742740.HMPREF9474_03976	1.7e-123	361.0	COG2207@1|root,COG3708@1|root,COG2207@2|Bacteria,COG3708@2|Bacteria,1TPI9@1239|Firmicutes,2496K@186801|Clostridia,223UP@1506553|Lachnoclostridium	186801|Clostridia	K	Bacterial transcription activator, effector binding domain	-	-	-	ko:K13653	-	-	-	-	ko00000,ko03000	-	-	-	Cass2,HTH_18
HALNLLBL_00033	936574.HMPREF1508_1355	4.01e-164	464.0	COG3177@1|root,COG3177@2|Bacteria,1TZWX@1239|Firmicutes,247MZ@186801|Clostridia	186801|Clostridia	E	Filamentation induced by cAMP protein fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic
HALNLLBL_00034	478749.BRYFOR_05591	4.03e-80	241.0	COG0716@1|root,COG0716@2|Bacteria,1V45R@1239|Firmicutes,24HDR@186801|Clostridia	186801|Clostridia	C	flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_4
HALNLLBL_00035	457396.CSBG_03069	2.61e-118	357.0	COG0038@1|root,COG0038@2|Bacteria,1TPX0@1239|Firmicutes,247R4@186801|Clostridia,36FR4@31979|Clostridiaceae	186801|Clostridia	P	Chloride channel	eriC	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
HALNLLBL_00036	585394.RHOM_14915	1.77e-172	488.0	COG3049@1|root,COG3049@2|Bacteria,1TPZS@1239|Firmicutes,24B0E@186801|Clostridia	186801|Clostridia	M	Linear amide C-N hydrolase, choloylglycine hydrolase family protein	cbh	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	CBAH
HALNLLBL_00038	411469.EUBHAL_01061	1.16e-212	595.0	COG0786@1|root,COG0786@2|Bacteria,1TQA4@1239|Firmicutes,247WX@186801|Clostridia,25V8Y@186806|Eubacteriaceae	186801|Clostridia	P	Catalyzes the sodium-dependent transport of glutamate	gltS	-	-	ko:K03312	-	-	-	-	ko00000,ko02000	2.A.27	-	-	Glt_symporter,NMT1_3
HALNLLBL_00039	471875.RUMLAC_02100	1.37e-101	308.0	COG2358@1|root,COG2358@2|Bacteria,1TPXW@1239|Firmicutes,2489U@186801|Clostridia,3WIYW@541000|Ruminococcaceae	186801|Clostridia	S	TRAP transporter solute receptor, TAXI family	bcsP	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
HALNLLBL_00040	428125.CLOLEP_02204	5.15e-159	458.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,3WH3G@541000|Ruminococcaceae	186801|Clostridia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
HALNLLBL_00041	537013.CLOSTMETH_03306	1.51e-15	84.7	COG1589@1|root,COG1589@2|Bacteria,1VKJ9@1239|Firmicutes,24P1N@186801|Clostridia,3WIGZ@541000|Ruminococcaceae	186801|Clostridia	D	Cell division protein FtsQ	-	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
HALNLLBL_00042	428125.CLOLEP_02201	1.61e-181	519.0	COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,2488W@186801|Clostridia,3WG8Y@541000|Ruminococcaceae	186801|Clostridia	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA2	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
HALNLLBL_00043	428125.CLOLEP_02200	4.01e-172	491.0	COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,248IA@186801|Clostridia,3WGFH@541000|Ruminococcaceae	186801|Clostridia	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
HALNLLBL_00044	1121334.KB911066_gene756	1.76e-124	374.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,3WHWW@541000|Ruminococcaceae	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
HALNLLBL_00045	428125.CLOLEP_02197	5.15e-122	361.0	COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,247S7@186801|Clostridia,3WHMP@541000|Ruminococcaceae	186801|Clostridia	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
HALNLLBL_00046	1105031.HMPREF1141_1551	1.74e-234	679.0	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,248KB@186801|Clostridia,36DJT@31979|Clostridiaceae	186801|Clostridia	M	stage V sporulation protein D	spoVD	-	3.4.16.4	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
HALNLLBL_00048	428125.CLOLEP_02193	4.31e-136	394.0	COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,248B5@186801|Clostridia,3WH07@541000|Ruminococcaceae	186801|Clostridia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
HALNLLBL_00049	1462526.BN990_02534	9.42e-30	112.0	COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,4HH23@91061|Bacilli,4C5KK@84406|Virgibacillus	91061|Bacilli	K	MraZ protein, putative antitoxin-like	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
HALNLLBL_00050	1120746.CCNL01000010_gene1105	2.19e-32	119.0	COG0711@1|root,COG0711@2|Bacteria	2|Bacteria	C	ATP synthesis coupled proton transport	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_00051	1120746.CCNL01000010_gene1104	1.79e-69	214.0	COG0669@1|root,COG0669@2|Bacteria,2NPDV@2323|unclassified Bacteria	2|Bacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	GO:0003674,GO:0003824,GO:0004595,GO:0005488,GO:0005515,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046390,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iPC815.YPO0053,iSDY_1059.SDY_4064	CTP_transf_like
HALNLLBL_00052	428125.CLOLEP_02183	6.67e-69	215.0	COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,24JHR@186801|Clostridia,3WJC4@541000|Ruminococcaceae	186801|Clostridia	L	RNA methyltransferase, RsmD family	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
HALNLLBL_00053	1121334.KB911069_gene1763	4.29e-274	769.0	COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,247TQ@186801|Clostridia,3WH2A@541000|Ruminococcaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
HALNLLBL_00054	537013.CLOSTMETH_02429	8.8e-48	153.0	COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,24QIP@186801|Clostridia,3WK5I@541000|Ruminococcaceae	186801|Clostridia	G	phosphocarrier, HPr family	ptsH	-	-	ko:K11184,ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
HALNLLBL_00055	428125.CLOLEP_02178	4.72e-124	358.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,247JF@186801|Clostridia,3WH8Z@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
HALNLLBL_00056	1105031.HMPREF1141_0216	4.94e-59	188.0	COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,24I1G@186801|Clostridia,36IPC@31979|Clostridiaceae	186801|Clostridia	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
HALNLLBL_00057	1105031.HMPREF1141_0222	6.36e-299	847.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,248YK@186801|Clostridia,36EFY@31979|Clostridiaceae	186801|Clostridia	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
HALNLLBL_00058	1120746.CCNL01000010_gene1088	7.54e-80	248.0	COG1381@1|root,COG1381@2|Bacteria	2|Bacteria	L	Involved in DNA repair and RecF pathway recombination	recO	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
HALNLLBL_00060	428125.CLOLEP_02165	7e-148	424.0	COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,24876@186801|Clostridia,3WGJ2@541000|Ruminococcaceae	186801|Clostridia	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
HALNLLBL_00061	877415.JNJQ01000002_gene2441	1.91e-10	62.4	COG0818@1|root,COG0818@2|Bacteria,1TU1J@1239|Firmicutes,3VRKX@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_prokar
HALNLLBL_00062	1121334.KB911069_gene1749	6.79e-82	246.0	COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,24MQZ@186801|Clostridia,3WIDY@541000|Ruminococcaceae	186801|Clostridia	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	3.5.4.5	ko:K01489,ko:K07042	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000,ko03009	-	-	-	UPF0054
HALNLLBL_00063	1105031.HMPREF1141_0230	2.15e-183	516.0	COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,247ZJ@186801|Clostridia,36UI2@31979|Clostridiaceae	186801|Clostridia	T	PhoH-like protein	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
HALNLLBL_00064	1120746.CCNL01000010_gene1094	6.89e-29	108.0	COG2739@1|root,COG2739@2|Bacteria	2|Bacteria	S	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein	ylxM	GO:0003674,GO:0008150,GO:0030234,GO:0030695,GO:0050790,GO:0060589,GO:0065007,GO:0065009,GO:0098772	-	ko:K09787	-	-	-	-	ko00000	-	-	-	UPF0122
HALNLLBL_00065	1120746.CCNL01000010_gene1095	2.17e-221	622.0	COG0541@1|root,COG0541@2|Bacteria,2NNT9@2323|unclassified Bacteria	2|Bacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
HALNLLBL_00066	445972.ANACOL_00448	5.61e-39	130.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,24MND@186801|Clostridia,3WJSQ@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
HALNLLBL_00067	1120746.CCNL01000010_gene1097	7.53e-31	110.0	COG1837@1|root,COG1837@2|Bacteria	2|Bacteria	L	Belongs to the UPF0109 family	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
HALNLLBL_00069	1105031.HMPREF1141_1643	0.0	1051.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,36DF4@31979|Clostridiaceae	186801|Clostridia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
HALNLLBL_00070	1105031.HMPREF1141_1642	2.69e-121	359.0	COG3869@1|root,COG3869@2|Bacteria,1TPBA@1239|Firmicutes,247SS@186801|Clostridia,36DF3@31979|Clostridiaceae	186801|Clostridia	E	Catalyzes the specific phosphorylation of arginine residues in proteins	mcsB	-	2.7.14.1	ko:K19405	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	ATP-gua_Ptrans
HALNLLBL_00071	592015.HMPREF1705_00208	5.98e-33	122.0	COG3880@1|root,COG3880@2|Bacteria,3TBG4@508458|Synergistetes	508458|Synergistetes	S	PFAM UvrB uvrC	-	-	-	ko:K19411	-	-	-	-	ko00000	-	-	-	UVR
HALNLLBL_00072	1105031.HMPREF1141_1640	2.37e-58	185.0	COG4463@1|root,COG4463@2|Bacteria,1VAXT@1239|Firmicutes,24JH3@186801|Clostridia,36JKR@31979|Clostridiaceae	186801|Clostridia	K	Belongs to the CtsR family	ctsR	-	-	ko:K03708	-	-	-	-	ko00000,ko03000	-	-	-	CtsR
HALNLLBL_00079	641112.ACOK01000106_gene700	3e-48	155.0	COG1278@1|root,COG1278@2|Bacteria,1VBBH@1239|Firmicutes,24QK9@186801|Clostridia,3WK5C@541000|Ruminococcaceae	186801|Clostridia	K	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
HALNLLBL_00080	861450.HMPREF0080_01893	2.22e-25	105.0	COG1595@1|root,COG1595@2|Bacteria,1TP55@1239|Firmicutes,4H2TH@909932|Negativicutes	909932|Negativicutes	K	Belongs to the sigma-70 factor family	sigH	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	GerE,Sigma70_r2,Sigma70_r4_2
HALNLLBL_00081	1120746.CCNL01000011_gene1511	1.27e-215	612.0	COG0606@1|root,COG0606@2|Bacteria,2NNW7@2323|unclassified Bacteria	2|Bacteria	O	Magnesium chelatase, subunit ChlI C-terminal	comM	-	-	ko:K06400,ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
HALNLLBL_00082	411467.BACCAP_02043	9.37e-27	99.0	COG1251@1|root,COG1251@2|Bacteria,1W1DD@1239|Firmicutes,25EHF@186801|Clostridia,269MR@186813|unclassified Clostridiales	186801|Clostridia	C	Domain of unknown function (DUF1858)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1858
HALNLLBL_00083	887325.HMPREF0381_1485	9.65e-43	150.0	COG2384@1|root,COG2384@2|Bacteria,1V3I4@1239|Firmicutes,24BJI@186801|Clostridia,1HUFJ@1164882|Lachnoanaerobaculum	186801|Clostridia	J	tRNA (adenine(22)-N(1))-methyltransferase	trmK	-	2.1.1.217	ko:K06967	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_18,TrmK
HALNLLBL_00084	428125.CLOLEP_02680	1.84e-71	226.0	COG0327@1|root,COG0327@2|Bacteria,1TQ27@1239|Firmicutes,248Q2@186801|Clostridia,3WJ9H@541000|Ruminococcaceae	186801|Clostridia	S	dinuclear metal center protein, YbgI	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
HALNLLBL_00085	290402.Cbei_0833	1.87e-87	264.0	COG0220@1|root,COG0220@2|Bacteria,1TQCA@1239|Firmicutes,248YR@186801|Clostridia,36DWU@31979|Clostridiaceae	186801|Clostridia	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
HALNLLBL_00086	428125.CLOLEP_01976	2.32e-39	154.0	COG0457@1|root,COG0457@2|Bacteria,1V0WM@1239|Firmicutes,24D57@186801|Clostridia,3WS6H@541000|Ruminococcaceae	186801|Clostridia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
HALNLLBL_00087	428125.CLOLEP_01977	4.45e-139	396.0	COG0745@1|root,COG0745@2|Bacteria,1TPN8@1239|Firmicutes,248UA@186801|Clostridia,3WGQR@541000|Ruminococcaceae	186801|Clostridia	K	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HALNLLBL_00088	1120746.CCNL01000017_gene3068	2.67e-154	454.0	COG5000@1|root,COG5002@1|root,COG5000@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	yclK	-	2.7.13.3	ko:K07636,ko:K07769	ko02020,map02020	M00434,M00466	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
HALNLLBL_00089	1120746.CCNL01000017_gene3067	2.03e-125	369.0	COG3872@1|root,COG3872@2|Bacteria,2NP59@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF1385)	prmC	-	-	-	-	-	-	-	-	-	-	-	DUF1385
HALNLLBL_00090	1120746.CCNL01000017_gene3066	1.21e-71	229.0	COG2890@1|root,COG2890@2|Bacteria,2NPDN@2323|unclassified Bacteria	2|Bacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006304,GO:0006305,GO:0006306,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009007,GO:0009008,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0032775,GO:0034641,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044728,GO:0046483,GO:0071704,GO:0090304,GO:0140096,GO:0140097,GO:1901360,GO:1901564	2.1.1.297,2.1.1.298	ko:K02493,ko:K07320	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03009,ko03012	-	-	-	MTS
HALNLLBL_00091	428125.CLOLEP_01982	3.3e-196	553.0	COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,247SF@186801|Clostridia,3WGST@541000|Ruminococcaceae	186801|Clostridia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
HALNLLBL_00092	428125.CLOLEP_01983	3.94e-68	214.0	COG2137@1|root,COG2137@2|Bacteria,1VAFI@1239|Firmicutes,25DPI@186801|Clostridia,3WSGY@541000|Ruminococcaceae	186801|Clostridia	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
HALNLLBL_00093	1105031.HMPREF1141_1371	1.28e-199	566.0	COG0621@1|root,COG0621@2|Bacteria,1TP2W@1239|Firmicutes,2487D@186801|Clostridia,36E1K@31979|Clostridiaceae	186801|Clostridia	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
HALNLLBL_00094	428125.CLOLEP_01985	3.64e-56	182.0	COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,24J7Y@186801|Clostridia,3WK01@541000|Ruminococcaceae	186801|Clostridia	I	CDP-alcohol phosphatidyltransferase	pgsA	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
HALNLLBL_00095	428125.CLOLEP_01986	1.36e-90	272.0	COG1045@1|root,COG1045@2|Bacteria,1TR42@1239|Firmicutes,249SF@186801|Clostridia,3WHD9@541000|Ruminococcaceae	186801|Clostridia	E	serine O-acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
HALNLLBL_00096	411467.BACCAP_02437	1.82e-253	705.0	COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,247KS@186801|Clostridia,2684B@186813|unclassified Clostridiales	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
HALNLLBL_00097	1120746.CCNL01000011_gene1653	1.33e-93	282.0	COG0726@1|root,COG0726@2|Bacteria,2NRM5@2323|unclassified Bacteria	2|Bacteria	G	Polysaccharide deacetylase	pdaB	GO:0005575,GO:0005623,GO:0016020,GO:0042763,GO:0044464	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
HALNLLBL_00099	138119.DSY0630	3.24e-08	53.9	COG1476@1|root,COG1476@2|Bacteria,1VEIS@1239|Firmicutes,24R6J@186801|Clostridia,265V1@186807|Peptococcaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
HALNLLBL_00100	573061.Clocel_1295	3.86e-34	141.0	COG1376@1|root,COG1376@2|Bacteria,1TQMA@1239|Firmicutes,248H0@186801|Clostridia,36DSK@31979|Clostridiaceae	186801|Clostridia	S	PFAM ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
HALNLLBL_00102	1341157.RF007C_11315	1.07e-74	238.0	COG3757@1|root,COG3757@2|Bacteria,1V5MP@1239|Firmicutes,24HFV@186801|Clostridia,3WS76@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyl hydrolases family 25	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_25
HALNLLBL_00103	1105031.HMPREF1141_3092	4.89e-66	204.0	COG1854@1|root,COG1854@2|Bacteria,1V1CH@1239|Firmicutes,24G3R@186801|Clostridia,36I3G@31979|Clostridiaceae	186801|Clostridia	H	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)	luxS	-	4.4.1.21	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	M00609	R01291	RC00069,RC01929	ko00000,ko00001,ko00002,ko01000	-	-	-	LuxS
HALNLLBL_00104	1120746.CCNL01000011_gene1617	1.14e-38	156.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	-	-	-	-	-	-	-	-	-	G5,LysM,Peptidase_M23
HALNLLBL_00105	693746.OBV_28270	6.9e-23	89.0	2DQKF@1|root,337FN@2|Bacteria,1VJ5N@1239|Firmicutes,24U9N@186801|Clostridia,2N7W3@216572|Oscillospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_00110	428125.CLOLEP_01125	2.57e-93	275.0	COG0219@1|root,COG0219@2|Bacteria,1V3GW@1239|Firmicutes,24HVV@186801|Clostridia,3WIDH@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
HALNLLBL_00111	1160721.RBI_II00637	2.53e-244	676.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,3WGM9@541000|Ruminococcaceae	186801|Clostridia	G	Phosphoglycerate kinase	pgk	-	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
HALNLLBL_00112	697329.Rumal_0090	2.54e-133	383.0	COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia,3WGWY@541000|Ruminococcaceae	186801|Clostridia	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS19265	TIM
HALNLLBL_00113	428125.CLOLEP_01129	2.45e-292	806.0	COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,247JG@186801|Clostridia,3WGBI@541000|Ruminococcaceae	186801|Clostridia	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
HALNLLBL_00114	428125.CLOLEP_00392	4.73e-243	687.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia,3WGTD@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HALNLLBL_00115	1235835.C814_03374	3.81e-238	675.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,3WGVP@541000|Ruminococcaceae	186801|Clostridia	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HALNLLBL_00116	445972.ANACOL_01687	2.04e-144	422.0	COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,2491V@186801|Clostridia,3WGK3@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
HALNLLBL_00117	411489.CLOL250_00996	8.32e-133	385.0	COG1284@1|root,COG1284@2|Bacteria,1TQTP@1239|Firmicutes,25CBN@186801|Clostridia,36WSY@31979|Clostridiaceae	186801|Clostridia	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
HALNLLBL_00118	428125.CLOLEP_01614	0.0	1060.0	COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia,3WGA7@541000|Ruminococcaceae	186801|Clostridia	J	translation elongation	fusA2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
HALNLLBL_00119	511680.BUTYVIB_01629	0.0	911.0	COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,247UC@186801|Clostridia,4BWZ5@830|Butyrivibrio	186801|Clostridia	EG	Dehydratase family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
HALNLLBL_00120	411468.CLOSCI_01782	7.09e-101	296.0	COG1896@1|root,COG1896@2|Bacteria,1V3MK@1239|Firmicutes,24IBW@186801|Clostridia,21ZZT@1506553|Lachnoclostridium	186801|Clostridia	S	HD domain	-	-	-	ko:K07023	-	-	-	-	ko00000	-	-	-	HD_3
HALNLLBL_00121	1298920.KI911353_gene4569	2.45e-206	585.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,21YBJ@1506553|Lachnoclostridium	186801|Clostridia	E	amino acid carrier protein	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
HALNLLBL_00122	1410617.JHXH01000007_gene1513	3.35e-72	225.0	COG0637@1|root,COG0637@2|Bacteria,1VA5Z@1239|Firmicutes,24JNY@186801|Clostridia,3WI50@541000|Ruminococcaceae	186801|Clostridia	S	IA, variant 3	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2,Mannitol_dh_C
HALNLLBL_00123	180332.JTGN01000002_gene5809	4.2e-77	245.0	COG0697@1|root,COG0697@2|Bacteria,1TRH8@1239|Firmicutes,24B85@186801|Clostridia	186801|Clostridia	EG	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HALNLLBL_00124	641107.CDLVIII_3733	1.85e-89	275.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,36E0J@31979|Clostridiaceae	186801|Clostridia	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
HALNLLBL_00125	1134510.O9A_00313	1.61e-25	99.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,2UCCR@28211|Alphaproteobacteria,48U4U@772|Bartonellaceae	28211|Alphaproteobacteria	O	Thioredoxin	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
HALNLLBL_00126	445973.CLOBAR_01153	1.44e-140	403.0	COG0648@1|root,COG0648@2|Bacteria,1TP1D@1239|Firmicutes,2499E@186801|Clostridia,25SGH@186804|Peptostreptococcaceae	186801|Clostridia	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
HALNLLBL_00129	428125.CLOLEP_01892	0.0	1165.0	COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,248M3@186801|Clostridia,3WGEX@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
HALNLLBL_00130	428125.CLOLEP_01888	2.36e-176	504.0	COG0826@1|root,COG0826@2|Bacteria,1TPRE@1239|Firmicutes,248I3@186801|Clostridia,3WGFB@541000|Ruminococcaceae	186801|Clostridia	O	Peptidase U32	yhbU_1	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
HALNLLBL_00131	1105031.HMPREF1141_2220	6.87e-105	325.0	COG1559@1|root,COG1559@2|Bacteria,1TS48@1239|Firmicutes,2493B@186801|Clostridia,36FDF@31979|Clostridiaceae	186801|Clostridia	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
HALNLLBL_00132	1120746.CCNL01000010_gene1426	6.1e-66	208.0	COG0212@1|root,COG0212@2|Bacteria,2NRKD@2323|unclassified Bacteria	2|Bacteria	H	5-formyltetrahydrofolate cyclo-ligase family	ygfA	GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	iECABU_c1320.ECABU_c31940,iECOK1_1307.ECOK1_3298,iECSF_1327.ECSF_2705,iUTI89_1310.UTI89_C3298	5-FTHF_cyc-lig
HALNLLBL_00133	1410617.JHXH01000001_gene936	7.66e-67	209.0	COG0693@1|root,COG0693@2|Bacteria,1V3WB@1239|Firmicutes,24HGU@186801|Clostridia,3WJ0K@541000|Ruminococcaceae	186801|Clostridia	S	DJ-1 family	yajL	-	3.5.1.124	ko:K03152	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
HALNLLBL_00134	762968.HMPREF9441_00004	2.66e-06	56.6	COG4552@1|root,COG4866@1|root,COG4552@2|Bacteria,COG4866@2|Bacteria,4NGJE@976|Bacteroidetes,2FNB2@200643|Bacteroidia	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	ko:K01163	-	-	-	-	ko00000	-	-	-	Acetyltransf_9,DUF2156
HALNLLBL_00135	1125701.HMPREF1221_00114	2.88e-62	206.0	COG4866@1|root,COG4866@2|Bacteria,2J5HZ@203691|Spirochaetes	203691|Spirochaetes	S	conserved protein (DUF2156)	-	-	-	ko:K01163	-	-	-	-	ko00000	-	-	-	DUF2156
HALNLLBL_00136	1105031.HMPREF1141_2215	1.38e-84	257.0	COG0125@1|root,COG0125@2|Bacteria,1V2D5@1239|Firmicutes,259SU@186801|Clostridia,36F78@31979|Clostridiaceae	186801|Clostridia	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS00680	Thymidylate_kin
HALNLLBL_00137	1384065.JAGS01000001_gene1007	2.55e-95	287.0	COG1351@1|root,COG1351@2|Bacteria,1TRAA@1239|Firmicutes,249DJ@186801|Clostridia,3WGNR@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
HALNLLBL_00138	33035.JPJF01000099_gene3597	3.33e-16	89.7	COG5492@1|root,COG5492@2|Bacteria,1VBT6@1239|Firmicutes,25B2B@186801|Clostridia,3Y2DX@572511|Blautia	186801|Clostridia	N	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Flg_new
HALNLLBL_00139	431943.CKL_3317	3.34e-14	72.4	COG1396@1|root,COG1396@2|Bacteria,1VK84@1239|Firmicutes,24QK6@186801|Clostridia,36MPM@31979|Clostridiaceae	186801|Clostridia	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
HALNLLBL_00140	1235792.C808_02449	1.23e-238	666.0	COG1301@1|root,COG1301@2|Bacteria,1TPME@1239|Firmicutes,247UX@186801|Clostridia,27JSN@186928|unclassified Lachnospiraceae	186801|Clostridia	C	Sodium:dicarboxylate symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
HALNLLBL_00141	1232447.BAHW02000009_gene339	9.29e-76	237.0	COG1349@1|root,COG1349@2|Bacteria,1UZ6T@1239|Firmicutes,24B16@186801|Clostridia	186801|Clostridia	K	transcriptional regulator DeoR family	-	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
HALNLLBL_00142	411460.RUMTOR_00802	6.21e-219	606.0	COG0667@1|root,COG0667@2|Bacteria,1TPIY@1239|Firmicutes,24AVD@186801|Clostridia,3XZZ3@572511|Blautia	186801|Clostridia	C	Aldo/keto reductase family	-	-	-	ko:K18471	ko00640,map00640	-	R10718	RC00739	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
HALNLLBL_00143	411460.RUMTOR_00803	3.51e-159	454.0	COG0524@1|root,COG0524@2|Bacteria,1UYF8@1239|Firmicutes,25MKN@186801|Clostridia,3Y0ZH@572511|Blautia	186801|Clostridia	G	Phosphomethylpyrimidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
HALNLLBL_00144	1232447.BAHW02000009_gene336	1.1e-191	533.0	COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia,268GH@186813|unclassified Clostridiales	186801|Clostridia	G	Fructose-bisphosphate aldolase class-II	-	-	-	-	-	-	-	-	-	-	-	-	F_bP_aldolase
HALNLLBL_00145	1232453.BAIF02000087_gene258	6.03e-216	600.0	COG1063@1|root,COG1063@2|Bacteria,1TPWP@1239|Firmicutes,24FHS@186801|Clostridia	186801|Clostridia	E	Glucose dehydrogenase C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
HALNLLBL_00146	1235792.C808_02440	5.91e-267	738.0	COG2271@1|root,COG2271@2|Bacteria,1UHSG@1239|Firmicutes,249UT@186801|Clostridia,27RBF@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Sugar (and other) transporter	-	-	-	ko:K08369	-	-	-	-	ko00000,ko02000	2.A.1	-	-	MFS_1,Sugar_tr
HALNLLBL_00147	1232447.BAHW02000009_gene333	5.05e-142	403.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,248AR@186801|Clostridia,268XI@186813|unclassified Clostridiales	186801|Clostridia	G	Ribulose-phosphate 3 epimerase family	-	-	5.1.3.1	ko:K01783,ko:K17195	ko00030,ko00040,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529,R09031	RC00540,RC03111	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
HALNLLBL_00148	1235792.C808_02438	8.67e-233	644.0	COG1063@1|root,COG1063@2|Bacteria,1TS6I@1239|Firmicutes,2493N@186801|Clostridia,27TH1@186928|unclassified Lachnospiraceae	186801|Clostridia	E	Glucose dehydrogenase C-terminus	-	-	1.1.1.103,1.1.1.14	ko:K00008,ko:K00060	ko00040,ko00051,ko00260,ko01100,map00040,map00051,map00260,map01100	M00014	R00875,R01465,R01896	RC00085,RC00102,RC00525	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
HALNLLBL_00149	428125.CLOLEP_02484	0.0	1298.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia,3WHFT@541000|Ruminococcaceae	186801|Clostridia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
HALNLLBL_00151	877414.ATWA01000045_gene1862	3.06e-48	156.0	COG0758@1|root,COG0758@2|Bacteria	2|Bacteria	LU	DNA mediated transformation	smf	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,DUF2493,MoCo_carrier
HALNLLBL_00152	1378168.N510_01349	1.61e-19	80.1	2EJ02@1|root,33CR7@2|Bacteria,1VPEQ@1239|Firmicutes	1239|Firmicutes	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Arc
HALNLLBL_00154	1280696.ATVY01000065_gene2588	8.41e-223	631.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia,4BW9U@830|Butyrivibrio	186801|Clostridia	G	Alpha-amylase domain	-	-	3.2.1.1,5.4.99.16	ko:K01176,ko:K05343	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
HALNLLBL_00157	428125.CLOLEP_02293	4.41e-30	111.0	COG1396@1|root,COG1396@2|Bacteria,1VK84@1239|Firmicutes,24SKI@186801|Clostridia,3WRBK@541000|Ruminococcaceae	186801|Clostridia	K	DNA-binding helix-turn-helix protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HALNLLBL_00158	428125.CLOLEP_02533	4.77e-187	560.0	COG2208@1|root,COG2208@2|Bacteria,1TQ92@1239|Firmicutes,247XG@186801|Clostridia,3WH68@541000|Ruminococcaceae	186801|Clostridia	KT	stage II sporulation protein E	spoIIE	-	3.1.3.16	ko:K06382	-	-	-	-	ko00000,ko01000	-	-	-	SpoIIE
HALNLLBL_00159	1105031.HMPREF1141_0112	2.99e-52	169.0	COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,24JGP@186801|Clostridia,36IV4@31979|Clostridiaceae	186801|Clostridia	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yrrK	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
HALNLLBL_00161	1160721.RBI_I00132	2.5e-24	93.6	COG1396@1|root,COG1396@2|Bacteria,1VK84@1239|Firmicutes,252JX@186801|Clostridia,3WKI0@541000|Ruminococcaceae	186801|Clostridia	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HALNLLBL_00162	397287.C807_01888	1.64e-40	139.0	COG3279@1|root,COG3279@2|Bacteria,1VEPW@1239|Firmicutes,24K2U@186801|Clostridia,27PK9@186928|unclassified Lachnospiraceae	186801|Clostridia	K	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR
HALNLLBL_00163	999413.HMPREF1094_04123	2.35e-36	129.0	2AH77@1|root,317H3@2|Bacteria,1V6I2@1239|Firmicutes,3VRJY@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Protein of unknown function (DUF3021)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3021
HALNLLBL_00164	428125.CLOLEP_03943	0.0	1868.0	COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia,3WGVS@541000|Ruminococcaceae	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
HALNLLBL_00165	428125.CLOLEP_03941	0.0	1958.0	COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,247J1@186801|Clostridia,3WH6H@541000|Ruminococcaceae	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
HALNLLBL_00167	641112.ACOK01000025_gene2768	9.29e-192	541.0	COG0037@1|root,COG0607@1|root,COG0037@2|Bacteria,COG0607@2|Bacteria,1TQ0Y@1239|Firmicutes,247RP@186801|Clostridia,3WGZH@541000|Ruminococcaceae	186801|Clostridia	D	Belongs to the TtcA family	ttcA	-	-	-	-	-	-	-	-	-	-	-	ATP_bind_3,Rhodanese
HALNLLBL_00168	515622.bpr_I0245	3.18e-52	194.0	COG2208@1|root,COG2208@2|Bacteria,1TQY5@1239|Firmicutes,249WB@186801|Clostridia,4BWYS@830|Butyrivibrio	186801|Clostridia	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HAMP,SpoIIE,dCache_1
HALNLLBL_00169	596329.HMPREF0631_1601	3.8e-42	169.0	COG2247@1|root,COG4870@1|root,COG2247@2|Bacteria,COG4870@2|Bacteria,1TVCW@1239|Firmicutes,25B7E@186801|Clostridia,25S9K@186804|Peptostreptococcaceae	186801|Clostridia	M	Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_2,CW_binding_2,Flg_new,Peptidase_C1
HALNLLBL_00170	428125.CLOLEP_02521	1.91e-107	320.0	COG0680@1|root,COG0680@2|Bacteria,1TPFY@1239|Firmicutes,248TE@186801|Clostridia,3WGVA@541000|Ruminococcaceae	186801|Clostridia	C	Initiates the rapid degradation of small, acid-soluble proteins during spore germination	gpr	-	3.4.24.78	ko:K06012	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_A25
HALNLLBL_00171	428125.CLOLEP_02523	1.61e-81	261.0	COG0860@1|root,COG0860@2|Bacteria,1TSFS@1239|Firmicutes,2488U@186801|Clostridia,3WGV1@541000|Ruminococcaceae	186801|Clostridia	M	stage II sporulation protein P	spoIIP	-	-	ko:K06385	-	-	-	-	ko00000	-	-	-	SpoIIP
HALNLLBL_00172	509191.AEDB02000087_gene2588	0.0	1398.0	COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3WHK1@541000|Ruminococcaceae	186801|Clostridia	C	belongs to the iron- containing alcohol dehydrogenase family	adhE	-	1.1.1.1,1.2.1.10	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	-	R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927	RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195	ko00000,ko00001,ko01000	-	-	-	Aldedh,Fe-ADH
HALNLLBL_00174	1514668.JOOA01000002_gene3336	5.75e-74	242.0	COG1323@1|root,COG1323@2|Bacteria,1TPP2@1239|Firmicutes,247UP@186801|Clostridia,3WI9X@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the UPF0348 family	-	-	-	-	-	-	-	-	-	-	-	-	HIGH_NTase1
HALNLLBL_00175	428125.CLOLEP_03328	1.15e-185	528.0	COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,3WH48@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
HALNLLBL_00176	1378168.N510_00350	8.77e-28	102.0	COG2155@1|root,COG2155@2|Bacteria,1VEQJ@1239|Firmicutes	1239|Firmicutes	S	Conserved protein	yuzA	-	-	ko:K09779	-	-	-	-	ko00000	-	-	-	DUF378
HALNLLBL_00178	883109.HMPREF0380_00643	2.56e-88	273.0	COG0679@1|root,COG0679@2|Bacteria,1TR9W@1239|Firmicutes,24AQF@186801|Clostridia,3WD6F@538999|Clostridiales incertae sedis	186801|Clostridia	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
HALNLLBL_00179	537007.BLAHAN_04980	2.65e-215	607.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,24865@186801|Clostridia,3XYZV@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
HALNLLBL_00180	1449050.JNLE01000003_gene2028	2.4e-276	792.0	COG0366@1|root,COG3291@1|root,COG0366@2|Bacteria,COG3291@2|Bacteria,1V0U1@1239|Firmicutes,24ZQ4@186801|Clostridia	186801|Clostridia	G	Alpha amylase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
HALNLLBL_00181	500632.CLONEX_02525	2.28e-80	250.0	COG0561@1|root,COG0561@2|Bacteria,1TREF@1239|Firmicutes,24PNN@186801|Clostridia	186801|Clostridia	S	HAD-superfamily hydrolase, subfamily IIB	yidA	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
HALNLLBL_00188	246199.CUS_7883	2.39e-180	523.0	COG1401@1|root,COG1401@2|Bacteria,1TRK1@1239|Firmicutes,24EKG@186801|Clostridia,3WI4A@541000|Ruminococcaceae	186801|Clostridia	V	ATPase associated with various cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_00189	877411.JMMA01000002_gene466	3.26e-28	114.0	COG0681@1|root,COG0681@2|Bacteria,1VH6F@1239|Firmicutes,259NA@186801|Clostridia,3WGDR@541000|Ruminococcaceae	186801|Clostridia	U	Peptidase S24-like	-	-	3.4.21.89	ko:K13280	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
HALNLLBL_00191	1410617.JHXH01000001_gene722	6.36e-41	149.0	2EV14@1|root,33NG8@2|Bacteria,1VU24@1239|Firmicutes,24Z1N@186801|Clostridia,3WHPM@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_00194	411489.CLOL250_01350	5.6e-66	207.0	COG1611@1|root,COG1611@2|Bacteria,1UKED@1239|Firmicutes,24DSN@186801|Clostridia,36GYE@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the LOG family	yvdD	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
HALNLLBL_00195	1415774.U728_1168	1.08e-117	359.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia,36FU2@31979|Clostridiaceae	186801|Clostridia	V	Mate efflux family protein	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
HALNLLBL_00196	562981.HMPREF0428_00382	4.52e-86	264.0	2DKY4@1|root,30URY@2|Bacteria,1V2IU@1239|Firmicutes,4ITR4@91061|Bacilli,3WFCY@539002|Bacillales incertae sedis	91061|Bacilli	S	Domain of unknown function (DUF4037)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4037,NTP_transf_2
HALNLLBL_00197	658086.HMPREF0994_04676	6.98e-41	136.0	COG3620@1|root,COG3620@2|Bacteria,1V77U@1239|Firmicutes,24UZE@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HALNLLBL_00198	658086.HMPREF0994_04675	9.47e-35	121.0	COG4679@1|root,COG4679@2|Bacteria,1VBJ4@1239|Firmicutes,24RVP@186801|Clostridia,27TNR@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Phage derived protein Gp49-like (DUF891)	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
HALNLLBL_00199	1499683.CCFF01000014_gene4056	1.45e-43	164.0	COG4990@1|root,COG4990@2|Bacteria,1V6EZ@1239|Firmicutes,24IBA@186801|Clostridia,36JXE@31979|Clostridiaceae	186801|Clostridia	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
HALNLLBL_00200	1120746.CCNL01000017_gene3268	2.1e-91	281.0	COG0196@1|root,COG0196@2|Bacteria,2NPCV@2323|unclassified Bacteria	2|Bacteria	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
HALNLLBL_00201	428125.CLOLEP_01760	4.68e-83	250.0	COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,24JFS@186801|Clostridia,3WJNN@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
HALNLLBL_00202	428125.CLOLEP_01759	5.44e-105	315.0	COG2866@1|root,COG2866@2|Bacteria,1TP3K@1239|Firmicutes,249MT@186801|Clostridia,3WHJW@541000|Ruminococcaceae	186801|Clostridia	EM	Carboxypeptidase	-	-	3.4.19.11	ko:K01308	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	LysM,PG_binding_1,Peptidase_M14
HALNLLBL_00203	428125.CLOLEP_03720	0.0	978.0	COG0367@1|root,COG0367@2|Bacteria,1TRPB@1239|Firmicutes,247YA@186801|Clostridia,3WGJR@541000|Ruminococcaceae	186801|Clostridia	E	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
HALNLLBL_00204	203119.Cthe_1399	2.24e-52	171.0	COG1433@1|root,COG1433@2|Bacteria,1V7KS@1239|Firmicutes,24J98@186801|Clostridia,3WJY6@541000|Ruminococcaceae	186801|Clostridia	S	TIGRFAM C_GCAxxG_C_C family	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
HALNLLBL_00205	428125.CLOLEP_01451	0.0	988.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,247V8@186801|Clostridia,3WGRU@541000|Ruminococcaceae	186801|Clostridia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
HALNLLBL_00206	658088.HMPREF0987_00851	1.17e-27	105.0	2DSCR@1|root,33FK0@2|Bacteria,1VKCD@1239|Firmicutes,24QWS@186801|Clostridia,27NWD@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Domain of unknown function (DUF3783)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3783
HALNLLBL_00207	471875.RUMLAC_02584	1.6e-42	154.0	COG0561@1|root,COG0561@2|Bacteria,1U3W2@1239|Firmicutes,2486H@186801|Clostridia,3WJGV@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
HALNLLBL_00208	1121334.KB911069_gene1473	2.5e-100	296.0	COG0177@1|root,COG0177@2|Bacteria,1TRAK@1239|Firmicutes,24899@186801|Clostridia,3WGWR@541000|Ruminococcaceae	186801|Clostridia	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
HALNLLBL_00209	999411.HMPREF1092_01739	9.5e-78	241.0	COG1011@1|root,COG1011@2|Bacteria,1UIG9@1239|Firmicutes,25EMR@186801|Clostridia,36G1V@31979|Clostridiaceae	186801|Clostridia	S	HAD-hyrolase-like	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
HALNLLBL_00210	411474.COPEUT_01923	7e-45	150.0	28KJ2@1|root,2ZA47@2|Bacteria,1TSHV@1239|Firmicutes,24CS7@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_00213	545697.HMPREF0216_00274	3.51e-10	68.6	COG1512@1|root,COG1512@2|Bacteria,1V8N5@1239|Firmicutes,24H2W@186801|Clostridia,36IYA@31979|Clostridiaceae	186801|Clostridia	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
HALNLLBL_00214	1235800.C819_00683	9.06e-138	419.0	COG0249@1|root,COG0249@2|Bacteria,1V2NH@1239|Firmicutes,25DRU@186801|Clostridia,27KIH@186928|unclassified Lachnospiraceae	186801|Clostridia	L	ATPase domain of DNA mismatch repair MUTS family	-	-	-	-	-	-	-	-	-	-	-	-	MutS_V
HALNLLBL_00215	1336241.JAEB01000008_gene1005	4.55e-12	62.4	COG4224@1|root,COG4224@2|Bacteria,1TUAX@1239|Firmicutes,24QS9@186801|Clostridia,25XPC@186806|Eubacteriaceae	186801|Clostridia	S	Bacterial protein of unknown function (DUF896)	ynzC	-	-	-	-	-	-	-	-	-	-	-	DUF896
HALNLLBL_00218	428125.CLOLEP_00295	0.0	1333.0	COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,248D8@186801|Clostridia,3WGVW@541000|Ruminococcaceae	186801|Clostridia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
HALNLLBL_00219	1120746.CCNL01000017_gene3208	5.61e-86	259.0	COG0193@1|root,COG0193@2|Bacteria,2NPQ7@2323|unclassified Bacteria	2|Bacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
HALNLLBL_00220	457421.CBFG_05521	2.4e-67	226.0	28JZ6@1|root,2Z9PA@2|Bacteria,1UQ35@1239|Firmicutes,24F3U@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_00221	1120746.CCNL01000017_gene3207	1.74e-171	485.0	COG0462@1|root,COG0462@2|Bacteria,2NNP6@2323|unclassified Bacteria	2|Bacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2848	Pribosyl_synth,Pribosyltran_N
HALNLLBL_00222	428125.CLOLEP_00300	1.7e-90	274.0	COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,248Z3@186801|Clostridia,3WGU5@541000|Ruminococcaceae	186801|Clostridia	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3,NTP_transferase
HALNLLBL_00223	411463.EUBVEN_02242	0.0	1558.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,25VEG@186806|Eubacteriaceae	186801|Clostridia	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
HALNLLBL_00224	1235792.C808_05193	1.63e-113	343.0	28K0P@1|root,2Z9QJ@2|Bacteria,1TSN2@1239|Firmicutes,24YHY@186801|Clostridia,27RCG@186928|unclassified Lachnospiraceae	186801|Clostridia	P	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
HALNLLBL_00225	1235792.C808_05194	1.55e-114	333.0	COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,248Z6@186801|Clostridia,27IBR@186928|unclassified Lachnospiraceae	186801|Clostridia	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
HALNLLBL_00226	1235798.C817_05113	5.91e-70	218.0	COG1309@1|root,COG1309@2|Bacteria,1V2BY@1239|Firmicutes,24PUI@186801|Clostridia	186801|Clostridia	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	WHG
HALNLLBL_00228	428125.CLOLEP_03675	5.59e-67	222.0	COG3299@1|root,COG3299@2|Bacteria,1UYY1@1239|Firmicutes,24FCN@186801|Clostridia,3WJSZ@541000|Ruminococcaceae	186801|Clostridia	S	Baseplate J-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
HALNLLBL_00238	1121334.KB911067_gene269	9.07e-152	436.0	28IS3@1|root,2Z8R9@2|Bacteria,1TSHH@1239|Firmicutes,24CQ6@186801|Clostridia,3WHGD@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Phage_capsid
HALNLLBL_00240	428125.CLOLEP_03662	8.9e-82	258.0	28MWX@1|root,2ZB45@2|Bacteria,1UZ34@1239|Firmicutes,24EV8@186801|Clostridia,3WIEZ@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_00241	428125.CLOLEP_03661	1.5e-115	348.0	28KHP@1|root,2ZA34@2|Bacteria,1TQEJ@1239|Firmicutes,249F6@186801|Clostridia,3WGJX@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Phage_portal
HALNLLBL_00242	1105031.HMPREF1141_0088	2.65e-202	572.0	COG1783@1|root,COG1783@2|Bacteria,1TT2C@1239|Firmicutes,24A7T@186801|Clostridia,36DG1@31979|Clostridiaceae	186801|Clostridia	S	phage terminase, large subunit, PBSX family	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6,Terminase_6C
HALNLLBL_00243	1160721.RBI_II00396	1.18e-17	82.0	2EQ5U@1|root,33HS4@2|Bacteria,1V3H5@1239|Firmicutes,24VF0@186801|Clostridia,3WKPZ@541000|Ruminococcaceae	186801|Clostridia	S	Terminase small subunit	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_2
HALNLLBL_00244	428125.CLOLEP_00407	6.4e-198	564.0	COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,248Q8@186801|Clostridia,3WHDF@541000|Ruminococcaceae	186801|Clostridia	EG	spore germination protein	spoVAF	-	-	ko:K06295,ko:K06408	-	-	-	-	ko00000	-	-	-	GerA
HALNLLBL_00245	140626.JHWB01000013_gene713	1.15e-41	139.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia	186801|Clostridia	O	Belongs to the thioredoxin family	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin
HALNLLBL_00246	428125.CLOLEP_03880	2.64e-162	467.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,248H9@186801|Clostridia,3WGQB@541000|Ruminococcaceae	186801|Clostridia	EH	D-isomer specific 2-hydroxyacid dehydrogenase	pdxB	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
HALNLLBL_00247	428125.CLOLEP_03881	2.28e-209	584.0	COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,247SM@186801|Clostridia,3WGD1@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
HALNLLBL_00248	1160721.RBI_I00681	1.41e-157	449.0	COG0284@1|root,COG0284@2|Bacteria,1TQ7P@1239|Firmicutes,247SZ@186801|Clostridia,3WH6X@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS17585	OMPdecase
HALNLLBL_00249	1336241.JAEB01000005_gene1441	1.68e-157	450.0	COG0119@1|root,COG0119@2|Bacteria,1TS0A@1239|Firmicutes,247MU@186801|Clostridia,25V7F@186806|Eubacteriaceae	186801|Clostridia	E	HMGL-like	-	-	4.1.3.39	ko:K01666	ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map01100,map01120,map01220	M00545,M00569	R00750	RC00307,RC00371	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
HALNLLBL_00250	1120746.CCNL01000017_gene2970	2.44e-188	536.0	COG0044@1|root,COG0044@2|Bacteria,2NNWP@2323|unclassified Bacteria	2|Bacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
HALNLLBL_00252	411473.RUMCAL_01644	8.39e-300	835.0	COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,248F8@186801|Clostridia,3WGUC@541000|Ruminococcaceae	186801|Clostridia	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
HALNLLBL_00253	1410670.JHXF01000001_gene2655	1.16e-245	699.0	COG1086@1|root,COG1086@2|Bacteria,1TR3W@1239|Firmicutes,247PW@186801|Clostridia,3WGZ4@541000|Ruminococcaceae	186801|Clostridia	GM	Polysaccharide biosynthesis protein	capD	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
HALNLLBL_00254	411467.BACCAP_00192	3.12e-49	171.0	COG1408@1|root,COG1408@2|Bacteria,1UU17@1239|Firmicutes,248PS@186801|Clostridia,2699X@186813|unclassified Clostridiales	186801|Clostridia	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
HALNLLBL_00255	1408823.AXUS01000007_gene2970	1.17e-10	70.1	COG2207@1|root,COG3664@1|root,COG2207@2|Bacteria,COG3664@2|Bacteria,1TQGI@1239|Firmicutes,2490Q@186801|Clostridia	186801|Clostridia	G	PFAM glycoside hydrolase family 39	-	-	3.2.1.37	ko:K01198	ko00520,ko01100,map00520,map01100	-	R01433	RC00467	ko00000,ko00001,ko01000	-	GH43	-	AraC_binding,Cupin_2,Glyco_hydro_39,HTH_18
HALNLLBL_00256	1408321.JNJD01000008_gene1949	3.08e-65	210.0	COG0062@1|root,COG0062@2|Bacteria,1VWCC@1239|Firmicutes,2513Y@186801|Clostridia,27UM7@186928|unclassified Lachnospiraceae	186801|Clostridia	G	YjeF-related protein N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	YjeF_N
HALNLLBL_00257	720554.Clocl_2092	6.39e-47	162.0	28RJ8@1|root,2ZDY4@2|Bacteria,1V64R@1239|Firmicutes,24HMT@186801|Clostridia,3WSS9@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_00264	476272.RUMHYD_00816	2.27e-19	101.0	COG1196@1|root,COG5492@1|root,COG1196@2|Bacteria,COG5492@2|Bacteria,1U4RJ@1239|Firmicutes,25K63@186801|Clostridia,3Y24N@572511|Blautia	186801|Clostridia	N	Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
HALNLLBL_00265	1384066.JAGT01000001_gene339	1.97e-37	129.0	COG1396@1|root,COG1396@2|Bacteria,1VGAT@1239|Firmicutes,24QWH@186801|Clostridia,3WK9M@541000|Ruminococcaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,HTH_31
HALNLLBL_00266	411467.BACCAP_02267	3.41e-65	209.0	COG0515@1|root,COG0515@2|Bacteria,1V7U3@1239|Firmicutes,25AZB@186801|Clostridia	186801|Clostridia	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
HALNLLBL_00267	1410617.JHXH01000008_gene2141	2.09e-36	129.0	2E529@1|root,32ZVG@2|Bacteria,1VGFJ@1239|Firmicutes,24R64@186801|Clostridia,3WKP9@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
HALNLLBL_00269	1160721.RBI_I01717	2.84e-67	206.0	COG1598@1|root,COG1598@2|Bacteria,1VAKM@1239|Firmicutes,24K5X@186801|Clostridia,3WKAK@541000|Ruminococcaceae	186801|Clostridia	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	ko:K18843	-	-	-	-	ko00000,ko02048	-	-	-	HicB_lk_antitox
HALNLLBL_00270	428125.CLOLEP_03259	5.39e-250	692.0	COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,248W5@186801|Clostridia,3WGJK@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
HALNLLBL_00271	1120746.CCNL01000004_gene64	4.48e-134	391.0	COG0042@1|root,COG0042@2|Bacteria,2NP3E@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
HALNLLBL_00273	1462527.CCDM010000003_gene3763	1.29e-41	141.0	COG2315@1|root,COG2315@2|Bacteria,1VBCB@1239|Firmicutes,4I30E@91061|Bacilli,23N4Y@182709|Oceanobacillus	1239|Firmicutes	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
HALNLLBL_00274	428125.CLOLEP_01968	4.93e-185	523.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,249AM@186801|Clostridia,3WGG1@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
HALNLLBL_00275	428125.CLOLEP_01967	0.0	935.0	COG0855@1|root,COG0855@2|Bacteria,1TNZM@1239|Firmicutes,248XY@186801|Clostridia,3WGAB@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
HALNLLBL_00276	483218.BACPEC_00627	1.23e-221	623.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,268FU@186813|unclassified Clostridiales	186801|Clostridia	S	Sodium:neurotransmitter symporter family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
HALNLLBL_00277	1160721.RBI_I01468	0.0	1051.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,248AU@186801|Clostridia,3WGEI@541000|Ruminococcaceae	186801|Clostridia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
HALNLLBL_00278	1121334.KB911077_gene2461	8.16e-100	298.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,248HE@186801|Clostridia,3WGAW@541000|Ruminococcaceae	186801|Clostridia	L	Hydrolase, TatD family	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
HALNLLBL_00281	1123288.SOV_3c03190	6.14e-99	291.0	COG1898@1|root,COG1898@2|Bacteria,1V2VG@1239|Firmicutes,4H7IN@909932|Negativicutes	909932|Negativicutes	M	dTDP-4-dehydrorhamnose 3,5-epimerase	-	-	-	-	-	-	-	-	-	-	-	-	dTDP_sugar_isom
HALNLLBL_00282	1230342.CTM_10046	1.25e-65	217.0	COG1442@1|root,COG1442@2|Bacteria,1VD1B@1239|Firmicutes,25BZQ@186801|Clostridia,36WMD@31979|Clostridiaceae	1239|Firmicutes	M	COG1442 Lipopolysaccharide biosynthesis proteins, LPS glycosyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_8
HALNLLBL_00283	180332.JTGN01000005_gene3065	1.19e-144	426.0	COG0438@1|root,COG0438@2|Bacteria,1V0JW@1239|Firmicutes,24CKB@186801|Clostridia	186801|Clostridia	M	Glycosyltransferase, group 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
HALNLLBL_00284	1437608.BBIA_1610	2.7e-43	158.0	COG0110@1|root,COG0438@1|root,COG0110@2|Bacteria,COG0438@2|Bacteria,2GNUB@201174|Actinobacteria,4D2Z2@85004|Bifidobacteriales	201174|Actinobacteria	M	Glycosyltransferase Family 4	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2
HALNLLBL_00285	1506994.JNLQ01000002_gene2912	5.84e-97	300.0	COG2327@1|root,COG2327@2|Bacteria,1V4VX@1239|Firmicutes,24C2N@186801|Clostridia,4C06B@830|Butyrivibrio	186801|Clostridia	S	Polysaccharide pyruvyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
HALNLLBL_00286	471875.RUMLAC_01267	1.03e-105	323.0	COG1035@1|root,COG1143@1|root,COG1035@2|Bacteria,COG1143@2|Bacteria,1TQGA@1239|Firmicutes,249BE@186801|Clostridia,3WIVM@541000|Ruminococcaceae	186801|Clostridia	C	PFAM Coenzyme F420 hydrogenase dehydrogenase, beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7,FrhB_FdhB_C,FrhB_FdhB_N
HALNLLBL_00287	500632.CLONEX_00164	3.16e-62	211.0	COG0438@1|root,COG0438@2|Bacteria,1TRCM@1239|Firmicutes,24B86@186801|Clostridia	186801|Clostridia	M	Glycosyltransferase, group 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
HALNLLBL_00288	1121333.JMLH01000021_gene1582	5.16e-116	376.0	COG1035@1|root,COG1143@1|root,COG1035@2|Bacteria,COG1143@2|Bacteria,1TQGA@1239|Firmicutes,3VTD6@526524|Erysipelotrichia	526524|Erysipelotrichia	C	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_7,FrhB_FdhB_C,FrhB_FdhB_N,PS_pyruv_trans
HALNLLBL_00289	720554.Clocl_2812	1.11e-33	137.0	COG3307@1|root,COG3307@2|Bacteria,1VNEW@1239|Firmicutes,24UU5@186801|Clostridia,3WR0W@541000|Ruminococcaceae	186801|Clostridia	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
HALNLLBL_00290	1449050.JNLE01000003_gene797	3.42e-114	351.0	COG2244@1|root,COG2244@2|Bacteria,1TRRI@1239|Firmicutes,24EFD@186801|Clostridia,36VW7@31979|Clostridiaceae	186801|Clostridia	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
HALNLLBL_00292	1121334.KB911075_gene1783	7.13e-84	254.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,248AR@186801|Clostridia,3WISD@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
HALNLLBL_00293	1384065.JAGS01000001_gene922	4.15e-50	198.0	COG2217@1|root,COG2217@2|Bacteria,1TXSW@1239|Firmicutes,25DZ4@186801|Clostridia,3WSHK@541000|Ruminococcaceae	186801|Clostridia	P	Heavy metal translocating P-type atpase	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_00294	537013.CLOSTMETH_01049	8.81e-103	306.0	COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,247SC@186801|Clostridia,3WGPU@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	yacO	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
HALNLLBL_00296	428125.CLOLEP_01488	5.65e-53	179.0	COG1051@1|root,COG1051@2|Bacteria,1VAMK@1239|Firmicutes,24RHG@186801|Clostridia,3WIE0@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
HALNLLBL_00297	1033737.CAEV01000056_gene3714	1.43e-62	213.0	28IAA@1|root,2Z8CW@2|Bacteria,1TQHP@1239|Firmicutes,248TG@186801|Clostridia,36F51@31979|Clostridiaceae	186801|Clostridia	S	DHHW protein	-	-	-	-	-	-	-	-	-	-	-	-	DHHW
HALNLLBL_00298	428125.CLOLEP_00283	3.87e-203	574.0	COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,248ZB@186801|Clostridia,3WGG5@541000|Ruminococcaceae	186801|Clostridia	EK	Aminotransferase, class I	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
HALNLLBL_00299	428125.CLOLEP_00284	2.89e-183	516.0	COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,248RC@186801|Clostridia,3WGS4@541000|Ruminococcaceae	186801|Clostridia	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
HALNLLBL_00300	1069534.LRC_01320	7.56e-69	229.0	COG5542@1|root,COG5542@2|Bacteria,1W76F@1239|Firmicutes,4II3P@91061|Bacilli,3FAKF@33958|Lactobacillaceae	91061|Bacilli	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_00301	511680.BUTYVIB_01582	1.01e-117	369.0	COG4805@1|root,COG4805@2|Bacteria,1TREN@1239|Firmicutes,249U9@186801|Clostridia	186801|Clostridia	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
HALNLLBL_00302	411483.FAEPRAA2165_01311	4.89e-165	479.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3WGKU@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HALNLLBL_00303	875454.BAEW01000002_gene430	1.18e-15	75.9	COG4416@1|root,COG4416@2|Bacteria,1VEMD@1239|Firmicutes,24MRR@186801|Clostridia,22HV7@1570339|Peptoniphilaceae	186801|Clostridia	S	COG NOG18757 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_00304	246199.CUS_7787	0.0	979.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1TPYV@1239|Firmicutes,248JB@186801|Clostridia,3WH5Y@541000|Ruminococcaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Pterin_bind,S-methyl_trans
HALNLLBL_00305	483218.BACPEC_01013	8.35e-65	207.0	COG1410@1|root,COG1410@2|Bacteria,1V7JJ@1239|Firmicutes,24AE1@186801|Clostridia,269GX@186813|unclassified Clostridiales	186801|Clostridia	E	Vitamin B12 dependent methionine synthase, activation domain	metH2	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Met_synt_B12
HALNLLBL_00306	411473.RUMCAL_02159	9.02e-131	379.0	COG0685@1|root,COG0685@2|Bacteria,1TQFE@1239|Firmicutes,247ZK@186801|Clostridia,3WH1U@541000|Ruminococcaceae	186801|Clostridia	E	5,10-methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
HALNLLBL_00307	1121344.JHZO01000006_gene1882	9.48e-198	563.0	COG2239@1|root,COG2239@2|Bacteria,1TP4V@1239|Firmicutes,2481R@186801|Clostridia,3WHBI@541000|Ruminococcaceae	186801|Clostridia	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
HALNLLBL_00312	702450.CUW_0899	9.83e-41	147.0	COG3764@1|root,COG3764@2|Bacteria,1V3I1@1239|Firmicutes,3VQVN@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Sortase family	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
HALNLLBL_00313	180332.JTGN01000019_gene1322	1.19e-66	217.0	COG3764@1|root,COG3764@2|Bacteria,1UN9R@1239|Firmicutes,24CEQ@186801|Clostridia	186801|Clostridia	M	sortase family	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
HALNLLBL_00314	762211.BSTEL_1717	1.54e-12	78.2	COG4932@1|root,COG4932@2|Bacteria,2H1EY@201174|Actinobacteria,4D00Q@85004|Bifidobacteriales	201174|Actinobacteria	M	LPXTG-motif cell wall anchor domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GramPos_pilinBB,Gram_pos_anchor
HALNLLBL_00315	1437600.JDUI01000010_gene181	5.52e-19	102.0	COG4932@1|root,COG4932@2|Bacteria,2I2FM@201174|Actinobacteria,4CZ4I@85004|Bifidobacteriales	201174|Actinobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cna_B,FctA,PA14,VWA_2
HALNLLBL_00316	428125.CLOLEP_00213	0.0	1320.0	COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,247N2@186801|Clostridia,3WGPN@541000|Ruminococcaceae	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
HALNLLBL_00317	1120746.CCNL01000008_gene473	1.45e-153	451.0	COG0768@1|root,COG0768@2|Bacteria	2|Bacteria	M	penicillin binding	-	-	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
HALNLLBL_00318	428125.CLOLEP_03718	4e-181	528.0	COG0772@1|root,COG0772@2|Bacteria,1TQ82@1239|Firmicutes,248QS@186801|Clostridia,3WI08@541000|Ruminococcaceae	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FHA,FTSW_RODA_SPOVE
HALNLLBL_00319	1035184.HMPREF1042_1246	3.5e-09	60.8	2EAJ6@1|root,334N3@2|Bacteria	2|Bacteria	S	Toxin ToxN, type III toxin-antitoxin system	-	-	-	ko:K19167	-	-	-	-	ko00000,ko02048	-	-	-	ToxN_toxin
HALNLLBL_00321	397287.C807_02623	1.87e-52	172.0	COG1268@1|root,COG1268@2|Bacteria,1VAY6@1239|Firmicutes,24HPU@186801|Clostridia,27NIJ@186928|unclassified Lachnospiraceae	186801|Clostridia	S	BioY family	bioY	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
HALNLLBL_00322	411463.EUBVEN_02660	7.77e-73	221.0	COG1959@1|root,COG1959@2|Bacteria,1V6FK@1239|Firmicutes,24K3Y@186801|Clostridia,25XNW@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
HALNLLBL_00323	641112.ACOK01000103_gene503	3.3e-101	301.0	COG2910@1|root,COG2910@2|Bacteria,1TZ3T@1239|Firmicutes,24DEZ@186801|Clostridia,3WJ0W@541000|Ruminococcaceae	186801|Clostridia	S	NAD(P)H-binding	-	-	-	ko:K07118	-	-	-	-	ko00000	-	-	-	NAD_binding_10
HALNLLBL_00324	500632.CLONEX_01175	9.61e-188	523.0	COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia	186801|Clostridia	G	Fructose-1,6-bisphosphate aldolase, class II	fba	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
HALNLLBL_00325	1120746.CCNL01000017_gene3138	8.67e-76	258.0	COG0265@1|root,COG0265@2|Bacteria,2NNVS@2323|unclassified Bacteria	2|Bacteria	O	smart pdz dhr glgf	htrA	-	3.4.21.107	ko:K04771,ko:K08372	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
HALNLLBL_00326	702459.BBPR_1112	1.84e-87	269.0	COG2865@1|root,COG2865@2|Bacteria,2IF0U@201174|Actinobacteria,4D0I9@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_00327	428125.CLOLEP_02468	1.64e-203	576.0	COG3581@1|root,COG3581@2|Bacteria,1TRVV@1239|Firmicutes,24947@186801|Clostridia,3WH15@541000|Ruminococcaceae	186801|Clostridia	I	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
HALNLLBL_00328	428125.CLOLEP_02467	0.0	1378.0	COG1924@1|root,COG3580@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,1TPU5@1239|Firmicutes,2481F@186801|Clostridia,3WGW6@541000|Ruminococcaceae	186801|Clostridia	I	CoA-substrate-specific enzyme activase	hgdC2	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229,HGD-D
HALNLLBL_00330	410358.Mlab_0596	2.61e-16	82.4	arCOG07861@1|root,arCOG07861@2157|Archaea	2157|Archaea	S	CpXC protein	-	-	-	-	-	-	-	-	-	-	-	-	CpXC
HALNLLBL_00332	428125.CLOLEP_03652	2.52e-167	473.0	COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,248I5@186801|Clostridia,3WG9U@541000|Ruminococcaceae	186801|Clostridia	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
HALNLLBL_00333	1120746.CCNL01000017_gene3121	4.64e-170	487.0	COG4992@1|root,COG4992@2|Bacteria,2NP1Z@2323|unclassified Bacteria	2|Bacteria	E	Aminotransferase class-III	argD	GO:0003674,GO:0003824,GO:0003992,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
HALNLLBL_00334	717606.PaecuDRAFT_2568	6.65e-44	147.0	COG0454@1|root,COG0456@2|Bacteria,1V4GU@1239|Firmicutes,4HQNT@91061|Bacilli,26XKA@186822|Paenibacillaceae	91061|Bacilli	K	GCN5 family acetyltransferase	-	-	2.3.1.1	ko:K22477	ko00220,ko01210,ko01230,map00220,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
HALNLLBL_00335	428125.CLOLEP_03650	8.82e-150	427.0	COG0548@1|root,COG0548@2|Bacteria,1TP0N@1239|Firmicutes,2486J@186801|Clostridia,3WGF0@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10565	AA_kinase
HALNLLBL_00336	428125.CLOLEP_03649	1.73e-180	515.0	COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,2497Q@186801|Clostridia,3WGSI@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
HALNLLBL_00337	428125.CLOLEP_03648	2.02e-183	517.0	COG0002@1|root,COG0002@2|Bacteria,1TPVI@1239|Firmicutes,247R3@186801|Clostridia,3WGZJ@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
HALNLLBL_00338	1120746.CCNL01000017_gene3125	1.62e-230	646.0	COG0165@1|root,COG0165@2|Bacteria,2NP70@2323|unclassified Bacteria	2|Bacteria	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,4.3.2.1	ko:K01755,ko:K14681	ko00220,ko00250,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map01100,map01110,map01130,map01210,map01230	M00028,M00029,M00844,M00845	R00259,R01086	RC00004,RC00064,RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Acetyltransf_1,Lyase_1
HALNLLBL_00339	428125.CLOLEP_03644	2.34e-240	667.0	COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,247MF@186801|Clostridia,3WGG9@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
HALNLLBL_00340	1121335.Clst_0225	1.71e-59	189.0	COG1853@1|root,COG1853@2|Bacteria,1V41U@1239|Firmicutes,24HTA@186801|Clostridia,3WJDN@541000|Ruminococcaceae	186801|Clostridia	S	Conserved protein domain typically associated with flavoprotein oxygenases DIM6 NTAB family	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
HALNLLBL_00341	1216932.CM240_0790	3.03e-178	575.0	COG0366@1|root,COG1501@1|root,COG0366@2|Bacteria,COG1501@2|Bacteria,1TP9E@1239|Firmicutes,248DX@186801|Clostridia,36DSD@31979|Clostridiaceae	186801|Clostridia	G	Alpha-amylase domain	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,CBM26
HALNLLBL_00342	1410633.JHWR01000009_gene1905	2.15e-74	245.0	COG0642@1|root,COG2205@2|Bacteria,1TT7F@1239|Firmicutes,247UJ@186801|Clostridia,27J5S@186928|unclassified Lachnospiraceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
HALNLLBL_00343	1304880.JAGB01000001_gene800	2.59e-74	231.0	COG0745@1|root,COG0745@2|Bacteria,1TT12@1239|Firmicutes,24AB1@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HALNLLBL_00344	742723.HMPREF9477_01003	3.84e-106	354.0	COG0577@1|root,COG0577@2|Bacteria,1TRAS@1239|Firmicutes,248SQ@186801|Clostridia,27K7N@186928|unclassified Lachnospiraceae	186801|Clostridia	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HALNLLBL_00345	1410633.JHWR01000009_gene1908	1.09e-111	326.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,27J1B@186928|unclassified Lachnospiraceae	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HALNLLBL_00346	1120746.CCNL01000017_gene3033	1.54e-144	416.0	COG2264@1|root,COG2264@2|Bacteria,2NPP7@2323|unclassified Bacteria	2|Bacteria	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
HALNLLBL_00347	428125.CLOLEP_00077	7.52e-189	534.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,248EM@186801|Clostridia,3WH82@541000|Ruminococcaceae	186801|Clostridia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
HALNLLBL_00348	1121334.KB911078_gene1162	0.0	941.0	COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,3WGES@541000|Ruminococcaceae	186801|Clostridia	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
HALNLLBL_00349	1120746.CCNL01000017_gene3180	4.64e-45	154.0	COG0576@1|root,COG0576@2|Bacteria,2NPSS@2323|unclassified Bacteria	2|Bacteria	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0017076,GO:0030234,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0044464,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0071496,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
HALNLLBL_00350	428125.CLOLEP_00080	1.81e-82	261.0	COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,247K2@186801|Clostridia,3WI1X@541000|Ruminococcaceae	186801|Clostridia	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
HALNLLBL_00352	1408436.JHXY01000049_gene257	6.91e-113	327.0	COG2184@1|root,COG2184@2|Bacteria,1TPUZ@1239|Firmicutes,248XF@186801|Clostridia,25W8Z@186806|Eubacteriaceae	186801|Clostridia	D	Fic/DOC family	fic	-	-	ko:K04095	-	-	-	-	ko00000,ko03036	-	-	-	Bro-N,Fic
HALNLLBL_00353	428125.CLOLEP_00323	1.22e-86	261.0	COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,24AXJ@186801|Clostridia,3WHGN@541000|Ruminococcaceae	186801|Clostridia	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
HALNLLBL_00354	556261.HMPREF0240_01326	9.21e-52	167.0	COG0494@1|root,COG0494@2|Bacteria,1UHVA@1239|Firmicutes,24PC0@186801|Clostridia,36K2C@31979|Clostridiaceae	186801|Clostridia	L	Nudix hydrolase	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
HALNLLBL_00356	428125.CLOLEP_01479	1.82e-202	565.0	2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia,3WGV8@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	GGGtGRT
HALNLLBL_00357	428125.CLOLEP_01481	1.22e-150	425.0	COG0822@1|root,COG0822@2|Bacteria,1TQEQ@1239|Firmicutes,248ID@186801|Clostridia,3WGYK@541000|Ruminococcaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	NifU_N
HALNLLBL_00358	1408324.JNJK01000043_gene842	3.77e-34	117.0	COG1476@1|root,COG1476@2|Bacteria,1VERT@1239|Firmicutes,24QJJ@186801|Clostridia,27PMY@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
HALNLLBL_00360	1507.HMPREF0262_00298	1.39e-26	98.6	2BRIM@1|root,32KHM@2|Bacteria,1US5F@1239|Firmicutes,24S12@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_00362	428125.CLOLEP_01746	5.37e-64	202.0	COG0779@1|root,COG0779@2|Bacteria,1V6KT@1239|Firmicutes,24N1G@186801|Clostridia,3WJSY@541000|Ruminococcaceae	186801|Clostridia	S	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
HALNLLBL_00363	428125.CLOLEP_01747	5.58e-153	442.0	COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,247W8@186801|Clostridia,3WG8A@541000|Ruminococcaceae	186801|Clostridia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
HALNLLBL_00364	1105031.HMPREF1141_1870	1.57e-38	131.0	COG2740@1|root,COG2740@2|Bacteria,1VEJS@1239|Firmicutes,24QSJ@186801|Clostridia,36KH1@31979|Clostridiaceae	186801|Clostridia	K	Nucleic-acid-binding protein implicated in transcription termination	ylxR	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
HALNLLBL_00365	1196323.ALKF01000205_gene4239	1.2e-06	50.8	COG1358@1|root,COG1358@2|Bacteria,1VEYG@1239|Firmicutes,4HNY7@91061|Bacilli,26Y6Y@186822|Paenibacillaceae	91061|Bacilli	J	ribosomal protein	ylxQ	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_L7Ae
HALNLLBL_00366	428125.CLOLEP_01750	0.0	1013.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia,3WHTD@541000|Ruminococcaceae	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
HALNLLBL_00367	428125.CLOLEP_01751	8.87e-54	171.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,24MPB@186801|Clostridia,3WJYA@541000|Ruminococcaceae	186801|Clostridia	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
HALNLLBL_00368	428125.CLOLEP_01752	1.32e-97	298.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,248R3@186801|Clostridia,3WGKS@541000|Ruminococcaceae	186801|Clostridia	S	domain protein	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
HALNLLBL_00369	1120746.CCNL01000017_gene3269	3.92e-101	305.0	COG0130@1|root,COG0130@2|Bacteria,2NP9J@2323|unclassified Bacteria	2|Bacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177,ko:K03483	-	-	-	-	ko00000,ko01000,ko03000,ko03016	-	-	iSB619.SA_RS06305	TruB-C_2,TruB_C_2,TruB_N
HALNLLBL_00371	720554.Clocl_3558	5.06e-132	382.0	COG0489@1|root,COG0489@2|Bacteria,1TQ34@1239|Firmicutes,24817@186801|Clostridia,3WGBQ@541000|Ruminococcaceae	186801|Clostridia	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	-	-	-	-	-	-	-	-	-	ParA
HALNLLBL_00374	1385514.N782_12495	2.53e-37	131.0	COG1476@1|root,COG1476@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,MazE_antitoxin
HALNLLBL_00375	1408303.JNJJ01000024_gene2951	1.03e-90	274.0	COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,4IPMF@91061|Bacilli,1ZRD4@1386|Bacillus	91061|Bacilli	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
HALNLLBL_00376	642492.Clole_3259	1.13e-96	290.0	COG1511@1|root,COG1511@2|Bacteria,1TPFN@1239|Firmicutes,24DWU@186801|Clostridia	186801|Clostridia	S	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
HALNLLBL_00377	78344.BIGA_0983	9.52e-69	219.0	COG3503@1|root,COG3503@2|Bacteria,2IJR9@201174|Actinobacteria,4D0YX@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
HALNLLBL_00378	428125.CLOLEP_03307	5.47e-60	194.0	2AUKD@1|root,31K93@2|Bacteria,1V6PK@1239|Firmicutes,24J91@186801|Clostridia,3WJSP@541000|Ruminococcaceae	186801|Clostridia	S	stage II sporulation protein R	spoIIR	-	-	ko:K06387	-	-	-	-	ko00000	-	-	-	Spore_II_R
HALNLLBL_00379	428125.CLOLEP_03308	5.63e-73	233.0	COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,24898@186801|Clostridia,3WH6J@541000|Ruminococcaceae	186801|Clostridia	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
HALNLLBL_00380	428125.CLOLEP_03309	3.64e-209	587.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,3WGAJ@541000|Ruminococcaceae	186801|Clostridia	E	Aminotransferase	aspC	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
HALNLLBL_00381	428125.CLOLEP_03310	4.88e-56	180.0	COG1522@1|root,COG1522@2|Bacteria,1V3PB@1239|Firmicutes,24I3N@186801|Clostridia,3WIWV@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulator, AsnC family	Lrp	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
HALNLLBL_00383	641112.ACOK01000112_gene2108	1.14e-282	793.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1TQ38@1239|Firmicutes,2484Z@186801|Clostridia,3WH2R@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
HALNLLBL_00384	428125.CLOLEP_01530	6.37e-51	188.0	COG3307@1|root,COG3307@2|Bacteria,1VK2G@1239|Firmicutes,24S8D@186801|Clostridia	186801|Clostridia	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
HALNLLBL_00385	944565.HMPREF9127_1108	3e-88	267.0	COG2148@1|root,COG2148@2|Bacteria,1TP7V@1239|Firmicutes,25AZD@186801|Clostridia,22JA8@1570339|Peptoniphilaceae	186801|Clostridia	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
HALNLLBL_00386	1121334.KB911074_gene2538	2.36e-31	113.0	COG3906@1|root,COG3906@2|Bacteria,1VF5Z@1239|Firmicutes,24V04@186801|Clostridia	186801|Clostridia	S	Belongs to the UPF0473 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1292
HALNLLBL_00387	357809.Cphy_3205	2.64e-131	383.0	COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,248JT@186801|Clostridia,21Z7T@1506553|Lachnoclostridium	186801|Clostridia	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
HALNLLBL_00388	1410626.JHXB01000001_gene2120	3.07e-36	150.0	COG1807@1|root,COG1807@2|Bacteria,1V6SZ@1239|Firmicutes,24J4S@186801|Clostridia,27PTC@186928|unclassified Lachnospiraceae	186801|Clostridia	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
HALNLLBL_00389	478749.BRYFOR_08717	2.57e-55	187.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,247ST@186801|Clostridia	186801|Clostridia	T	EDD domain protein, DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
HALNLLBL_00390	485916.Dtox_2894	1.7e-56	197.0	28NW3@1|root,2ZBU0@2|Bacteria,1V2IM@1239|Firmicutes,24GA1@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
HALNLLBL_00391	411460.RUMTOR_01012	2.24e-24	99.4	COG0681@1|root,COG0681@2|Bacteria,1VBMP@1239|Firmicutes,25DY3@186801|Clostridia,3Y282@572511|Blautia	186801|Clostridia	U	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_00392	485916.Dtox_2892	2.76e-26	99.4	2E5V7@1|root,330JA@2|Bacteria,1VFNT@1239|Firmicutes,24RD2@186801|Clostridia,2667Z@186807|Peptococcaceae	186801|Clostridia	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
HALNLLBL_00393	1121334.KB911066_gene912	1.76e-300	830.0	COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,3WGUG@541000|Ruminococcaceae	186801|Clostridia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
HALNLLBL_00394	1105031.HMPREF1141_2106	5.68e-45	147.0	COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,24MMM@186801|Clostridia,36KFP@31979|Clostridiaceae	186801|Clostridia	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
HALNLLBL_00395	428125.CLOLEP_02911	3.82e-105	333.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1V4RJ@1239|Firmicutes,24IFN@186801|Clostridia,3WGT2@541000|Ruminococcaceae	186801|Clostridia	KLT	PASTA domain protein	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
HALNLLBL_00397	657322.FPR_30250	6.34e-27	109.0	COG1564@1|root,COG1564@2|Bacteria,1VA0W@1239|Firmicutes,24NG6@186801|Clostridia,3WJUT@541000|Ruminococcaceae	186801|Clostridia	H	thiamine pyrophosphokinase	thiN	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
HALNLLBL_00398	428125.CLOLEP_02345	1.36e-112	334.0	COG1162@1|root,COG1162@2|Bacteria,1TPSQ@1239|Firmicutes,248R5@186801|Clostridia,3WGGY@541000|Ruminococcaceae	186801|Clostridia	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
HALNLLBL_00399	1105031.HMPREF1141_3005	1.06e-223	647.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,36DBS@31979|Clostridiaceae	186801|Clostridia	KLT	serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
HALNLLBL_00400	1120746.CCNL01000011_gene1708	1.63e-77	241.0	COG0631@1|root,COG0631@2|Bacteria,2NR1Q@2323|unclassified Bacteria	2|Bacteria	T	Serine/threonine phosphatases, family 2C, catalytic domain	stp	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
HALNLLBL_00401	1105031.HMPREF1141_3003	3.56e-157	451.0	COG0820@1|root,COG0820@2|Bacteria,1TPVF@1239|Firmicutes,248BC@186801|Clostridia,36E1B@31979|Clostridiaceae	186801|Clostridia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
HALNLLBL_00402	428125.CLOLEP_02341	1.61e-141	419.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1TP3N@1239|Firmicutes,248CS@186801|Clostridia,3WGKM@541000|Ruminococcaceae	186801|Clostridia	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
HALNLLBL_00403	1120746.CCNL01000011_gene1705	2.33e-78	242.0	COG2738@1|root,COG2738@2|Bacteria,2NPB1@2323|unclassified Bacteria	2|Bacteria	S	Putative neutral zinc metallopeptidase	yugP	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
HALNLLBL_00404	1384065.JAGS01000001_gene798	2.99e-112	334.0	COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,248ED@186801|Clostridia,3WGPQ@541000|Ruminococcaceae	186801|Clostridia	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
HALNLLBL_00405	428125.CLOLEP_02338	8.47e-64	199.0	COG0242@1|root,COG0242@2|Bacteria,1V70B@1239|Firmicutes,24JET@186801|Clostridia,3WJGJ@541000|Ruminococcaceae	186801|Clostridia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
HALNLLBL_00406	428125.CLOLEP_02337	0.0	919.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,248EI@186801|Clostridia,3WGTG@541000|Ruminococcaceae	186801|Clostridia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
HALNLLBL_00408	537013.CLOSTMETH_02652	4.55e-60	193.0	COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,24HEX@186801|Clostridia,3WIUW@541000|Ruminococcaceae	186801|Clostridia	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
HALNLLBL_00409	1507.HMPREF0262_02222	3.2e-27	101.0	COG2052@1|root,COG2052@2|Bacteria,1VA40@1239|Firmicutes,24MXV@186801|Clostridia,36JMX@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the UPF0296 family	NPD7_560	-	-	ko:K09777	-	-	-	-	ko00000	-	-	-	DUF370
HALNLLBL_00410	1120746.CCNL01000011_gene1698	1.3e-117	346.0	COG1561@1|root,COG1561@2|Bacteria,2NPG5@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF1732)	yicC	GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009022,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:0140101,GO:1901360,GO:1901361,GO:1901575	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	DUF1732,YicC_N
HALNLLBL_00411	428125.CLOLEP_02910	1.42e-127	368.0	COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,247NK@186801|Clostridia,3WHDN@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulatory protein	yebC	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
HALNLLBL_00413	1120746.CCNL01000011_gene1583	8.47e-281	790.0	COG0539@1|root,COG0761@1|root,COG0539@2|Bacteria,COG0761@2|Bacteria,2NNTP@2323|unclassified Bacteria	2|Bacteria	J	Ribosomal protein S1	ispH	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0042380,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046490,GO:0048037,GO:0051536,GO:0051538,GO:0051540,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.17.7.4,2.7.4.25	ko:K00945,ko:K02945,ko:K03527	ko00240,ko00900,ko01100,ko01110,ko01130,ko03010,map00240,map00900,map01100,map01110,map01130,map03010	M00052,M00096,M00178	R00158,R00512,R01665,R05884,R08210	RC00002,RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	iECIAI1_1343.ECIAI1_0030,iECW_1372.ECW_m0028,iEKO11_1354.EKO11_3884,iEcHS_1320.EcHS_A0031,iEcolC_1368.EcolC_3626,iIT341.HP0400,iLJ478.TM1444,iPC815.YPO0477,iSFV_1184.SFV_0023,iSF_1195.SF0026,iSFxv_1172.SFxv_0027,iS_1188.S0028,iWFL_1372.ECW_m0028,iYL1228.KPN_00024	LYTB,S1
HALNLLBL_00414	428125.CLOLEP_03183	2.06e-43	151.0	COG0204@1|root,COG0204@2|Bacteria,1UMJA@1239|Firmicutes,249AV@186801|Clostridia,3WS6N@541000|Ruminococcaceae	186801|Clostridia	I	Phosphate acyltransferases	plsC_1	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
HALNLLBL_00415	1120746.CCNL01000011_gene1580	7.98e-83	253.0	COG0283@1|root,COG0283@2|Bacteria,2NPCE@2323|unclassified Bacteria	2|Bacteria	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.19,2.7.4.25,6.3.2.1	ko:K00800,ko:K00945,ko:K03977,ko:K13799	ko00240,ko00400,ko00410,ko00770,ko01100,ko01110,ko01130,ko01230,map00240,map00400,map00410,map00770,map01100,map01110,map01130,map01230	M00022,M00052,M00119	R00158,R00512,R01665,R02473,R03460	RC00002,RC00096,RC00141,RC00350	ko00000,ko00001,ko00002,ko01000,ko03009	-	-	-	Cytidylate_kin,Pantoate_ligase
HALNLLBL_00416	1120746.CCNL01000011_gene1579	1.83e-174	500.0	COG2081@1|root,COG2081@2|Bacteria,2NPCB@2323|unclassified Bacteria	2|Bacteria	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
HALNLLBL_00417	428125.CLOLEP_03186	3.16e-127	370.0	COG1737@1|root,COG1737@2|Bacteria,1TP7H@1239|Firmicutes,248ZD@186801|Clostridia,3WGRZ@541000|Ruminococcaceae	186801|Clostridia	K	transcriptional regulator RpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
HALNLLBL_00418	428125.CLOLEP_03235	1.42e-97	289.0	COG0118@1|root,COG0118@2|Bacteria,1TQT0@1239|Firmicutes,248SH@186801|Clostridia,3WGIA@541000|Ruminococcaceae	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
HALNLLBL_00419	428125.CLOLEP_03234	1.31e-128	371.0	COG0107@1|root,COG0107@2|Bacteria,1TP0W@1239|Firmicutes,24900@186801|Clostridia,3WGQE@541000|Ruminococcaceae	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
HALNLLBL_00420	1216932.CM240_0788	7.23e-104	357.0	COG0366@1|root,COG0860@1|root,COG3664@1|root,COG0366@2|Bacteria,COG0860@2|Bacteria,COG3664@2|Bacteria,1TQSE@1239|Firmicutes,24C4V@186801|Clostridia,36GZS@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Big_2,CBM26,CBM53,CW_binding_1,Y_Y_Y
HALNLLBL_00422	511680.BUTYVIB_01595	5.68e-210	611.0	COG0366@1|root,COG0366@2|Bacteria,1TQSE@1239|Firmicutes,24C4V@186801|Clostridia,4BWVW@830|Butyrivibrio	186801|Clostridia	G	Starch-binding module 26	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Big_2,CBM26,CW_binding_1,Y_Y_Y
HALNLLBL_00423	1216932.CM240_2796	5.23e-55	191.0	COG0463@1|root,COG0463@2|Bacteria,1TQ8C@1239|Firmicutes,248MK@186801|Clostridia,36IDZ@31979|Clostridiaceae	186801|Clostridia	M	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,GtrA
HALNLLBL_00424	1235797.C816_01590	1.85e-135	389.0	COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,247WW@186801|Clostridia,2N6JV@216572|Oscillospiraceae	186801|Clostridia	S	ATPases associated with a variety of cellular activities	-	-	-	ko:K05833	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
HALNLLBL_00425	1469948.JPNB01000001_gene2244	7.52e-132	385.0	COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,249P1@186801|Clostridia,36EMV@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K05832	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	BPD_transp_2
HALNLLBL_00426	1469948.JPNB01000001_gene2245	7.27e-136	397.0	COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,248X3@186801|Clostridia,36EB5@31979|Clostridiaceae	186801|Clostridia	S	ABC transporter	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
HALNLLBL_00427	1120746.CCNL01000011_gene1888	0.0	1441.0	COG0587@1|root,COG0587@2|Bacteria,2NNVY@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
HALNLLBL_00428	428125.CLOLEP_03165	3.33e-137	405.0	COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,247KE@186801|Clostridia,3WGCP@541000|Ruminococcaceae	186801|Clostridia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
HALNLLBL_00429	428125.CLOLEP_03166	9.91e-115	341.0	COG0533@1|root,COG0533@2|Bacteria,1TRPY@1239|Firmicutes,24CN4@186801|Clostridia,3WG7R@541000|Ruminococcaceae	186801|Clostridia	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	gcp1	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
HALNLLBL_00430	1121334.KB911066_gene552	2.38e-31	117.0	COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,24MQ3@186801|Clostridia,3WK9U@541000|Ruminococcaceae	186801|Clostridia	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
HALNLLBL_00431	1121344.JHZO01000004_gene1612	7.61e-09	60.5	2E3US@1|root,32YS3@2|Bacteria	2|Bacteria	S	Stage III sporulation protein	spoIIIAH	-	-	ko:K06397	-	-	-	-	ko00000	1.A.34.1.1	-	-	SpoIIIAH
HALNLLBL_00432	428125.CLOLEP_03169	1.14e-14	74.7	2E6BB@1|root,32FH3@2|Bacteria,1V7J4@1239|Firmicutes,24J8Z@186801|Clostridia,3WKIY@541000|Ruminococcaceae	186801|Clostridia	S	stage III sporulation protein AG	spoIIIAG	-	-	ko:K06396	-	-	-	-	ko00000	-	-	-	-
HALNLLBL_00434	1120746.CCNL01000011_gene1594	2.21e-52	185.0	2C2CG@1|root,2Z7PW@2|Bacteria	2|Bacteria	S	stage III sporulation protein AE	spoIIIAE	-	-	ko:K06394	-	-	-	-	ko00000	-	-	-	Spore_III_AE
HALNLLBL_00435	537013.CLOSTMETH_02786	1.37e-18	82.8	2CPUI@1|root,32SJW@2|Bacteria,1VA9Y@1239|Firmicutes,24NK6@186801|Clostridia	186801|Clostridia	S	Stage III sporulation protein AD	spoIIIAD	-	-	ko:K06393	-	-	-	-	ko00000	-	-	-	SpoIIIAC
HALNLLBL_00436	537013.CLOSTMETH_02787	1.35e-23	90.9	2E555@1|root,32ZY3@2|Bacteria,1VEM4@1239|Firmicutes,24QNR@186801|Clostridia,3WKGF@541000|Ruminococcaceae	186801|Clostridia	S	stage III sporulation protein AC	spoIIIAC	-	-	ko:K06392	-	-	-	-	ko00000	-	-	-	SpoIIIAC
HALNLLBL_00438	428125.CLOLEP_03176	8.24e-83	260.0	COG3854@1|root,COG3854@2|Bacteria,1TQ23@1239|Firmicutes,248S2@186801|Clostridia,3WGH3@541000|Ruminococcaceae	186801|Clostridia	S	stage III sporulation protein AA	spoIIIAA	-	-	ko:K06390	-	-	-	-	ko00000	-	-	-	T2SSE
HALNLLBL_00440	428125.CLOLEP_03177	8.6e-295	825.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,248AX@186801|Clostridia,3WGTP@541000|Ruminococcaceae	186801|Clostridia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
HALNLLBL_00441	428125.CLOLEP_00564	4.05e-99	291.0	COG3481@1|root,COG3481@2|Bacteria,1TQEK@1239|Firmicutes,24BRR@186801|Clostridia,3WIKZ@541000|Ruminococcaceae	186801|Clostridia	S	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
HALNLLBL_00443	428125.CLOLEP_03264	1.58e-153	444.0	COG0116@1|root,COG0116@2|Bacteria,1TP0X@1239|Firmicutes,248MA@186801|Clostridia,3WGN5@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the methyltransferase superfamily	ypsC	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
HALNLLBL_00444	1105031.HMPREF1141_2103	1.37e-67	211.0	COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,24HDH@186801|Clostridia,36I5Z@31979|Clostridiaceae	186801|Clostridia	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
HALNLLBL_00445	1120746.CCNL01000011_gene1826	3.03e-43	147.0	COG1098@1|root,COG1098@2|Bacteria	2|Bacteria	J	S1 RNA binding domain	yabR	-	-	ko:K07570,ko:K07571	-	-	-	-	ko00000	-	-	-	S1
HALNLLBL_00446	394503.Ccel_3081	4.93e-06	49.3	COG2919@1|root,COG2919@2|Bacteria,1VKC5@1239|Firmicutes,24KC3@186801|Clostridia,36S1E@31979|Clostridiaceae	186801|Clostridia	D	PFAM Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
HALNLLBL_00448	428125.CLOLEP_03271	4.44e-18	79.0	2E3ZZ@1|root,32YWW@2|Bacteria,1VEIW@1239|Firmicutes,24QNQ@186801|Clostridia,3WKKJ@541000|Ruminococcaceae	186801|Clostridia	S	Sporulation protein YabP	yabP	-	-	-	-	-	-	-	-	-	-	-	YabP
HALNLLBL_00449	411473.RUMCAL_01132	1.47e-34	119.0	COG1188@1|root,COG1188@2|Bacteria,1VEI5@1239|Firmicutes,24QNF@186801|Clostridia,3WKNC@541000|Ruminococcaceae	186801|Clostridia	J	S4 domain protein	hslR	-	-	-	-	-	-	-	-	-	-	-	S4
HALNLLBL_00450	1262915.BN574_01345	6.65e-36	124.0	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,4H539@909932|Negativicutes	909932|Negativicutes	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
HALNLLBL_00451	428125.CLOLEP_03108	1.86e-123	359.0	COG1694@1|root,COG3956@2|Bacteria,1TPK1@1239|Firmicutes,247XM@186801|Clostridia,3WHY1@541000|Ruminococcaceae	186801|Clostridia	S	MazG family	mazG	-	3.6.1.66	ko:K02428,ko:K02499	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG,TP_methylase
HALNLLBL_00452	428125.CLOLEP_03106	2.27e-165	492.0	COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,2485G@186801|Clostridia,3WH0Z@541000|Ruminococcaceae	186801|Clostridia	S	Polysaccharide biosynthesis protein	-	-	-	ko:K06409	-	-	-	-	ko00000,ko02000	2.A.66.2.14	-	-	Polysacc_synt,Polysacc_synt_C
HALNLLBL_00454	428125.CLOLEP_03103	3.77e-180	520.0	COG0635@1|root,COG0635@2|Bacteria,1TREM@1239|Firmicutes,247JT@186801|Clostridia,3WGA8@541000|Ruminococcaceae	186801|Clostridia	C	Coproporphyrinogen dehydrogenase	hemZ	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
HALNLLBL_00455	97138.C820_01432	6.13e-54	178.0	COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,24JGV@186801|Clostridia,36I3Z@31979|Clostridiaceae	186801|Clostridia	S	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HALNLLBL_00456	537013.CLOSTMETH_01174	8.01e-67	207.0	COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,24J90@186801|Clostridia,3WJM2@541000|Ruminococcaceae	186801|Clostridia	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
HALNLLBL_00457	428125.CLOLEP_03100	0.0	890.0	COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,2489A@186801|Clostridia,3WGUK@541000|Ruminococcaceae	186801|Clostridia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS16615	ACT_4,HD_4,RelA_SpoT,TGS
HALNLLBL_00458	428125.CLOLEP_03099	1.85e-234	675.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,247NU@186801|Clostridia,3WI09@541000|Ruminococcaceae	186801|Clostridia	L	exonuclease	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
HALNLLBL_00459	1120746.CCNL01000011_gene1758	3.3e-172	506.0	COG0497@1|root,COG0497@2|Bacteria,2NNUS@2323|unclassified Bacteria	2|Bacteria	L	May be involved in recombinational repair of damaged DNA	recN	GO:0000724,GO:0000725,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009295,GO:0009314,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071944,GO:0090304,GO:1901360	-	ko:K03631,ko:K13582	ko04112,map04112	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_23,SMC_N
HALNLLBL_00460	1121334.KB911066_gene620	1.73e-53	173.0	COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,24HGQ@186801|Clostridia,3WJZ0@541000|Ruminococcaceae	186801|Clostridia	K	Regulates arginine biosynthesis genes	argR	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
HALNLLBL_00461	428125.CLOLEP_03160	1.39e-79	249.0	COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,24BG6@186801|Clostridia,3WHYS@541000|Ruminococcaceae	186801|Clostridia	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS05480	NAD_kinase
HALNLLBL_00462	1120746.CCNL01000011_gene1761	1.01e-129	375.0	COG1189@1|root,COG1189@2|Bacteria,2NPHR@2323|unclassified Bacteria	2|Bacteria	J	FtsJ-like methyltransferase	rrmJ	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
HALNLLBL_00463	428125.CLOLEP_03162	4.04e-264	744.0	COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,247P1@186801|Clostridia,3WGVF@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
HALNLLBL_00464	428125.CLOLEP_03163	6.45e-116	342.0	COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,248DE@186801|Clostridia,3WINP@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	iHN637.CLJU_RS05465	polyprenyl_synt
HALNLLBL_00465	926561.KB900623_gene897	3.48e-05	45.1	COG1722@1|root,COG1722@2|Bacteria,1VK9I@1239|Firmicutes,24UH5@186801|Clostridia,3WC6B@53433|Halanaerobiales	186801|Clostridia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
HALNLLBL_00466	1105031.HMPREF1141_2479	5.74e-84	262.0	COG1481@1|root,COG1481@2|Bacteria,1TP2X@1239|Firmicutes,2484M@186801|Clostridia,36EVX@31979|Clostridiaceae	186801|Clostridia	K	May be required for sporulation	whiA	-	-	ko:K09762	-	-	-	-	ko00000	-	-	-	HTH_WhiA,LAGLIDADG_WhiA,WhiA_N
HALNLLBL_00467	428125.CLOLEP_00068	2.54e-105	315.0	COG1660@1|root,COG1660@2|Bacteria,1TPS4@1239|Firmicutes,248KQ@186801|Clostridia,3WGDD@541000|Ruminococcaceae	186801|Clostridia	S	Displays ATPase and GTPase activities	yvcJ	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
HALNLLBL_00468	428125.CLOLEP_00067	4.62e-100	303.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,247IU@186801|Clostridia,3WGX6@541000|Ruminococcaceae	186801|Clostridia	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
HALNLLBL_00469	1105031.HMPREF1141_2476	1.02e-143	415.0	COG1493@1|root,COG1493@2|Bacteria,1TP5Z@1239|Firmicutes,24999@186801|Clostridia,36F8F@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
HALNLLBL_00472	428125.CLOLEP_01990	1.1e-177	515.0	COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,248Q8@186801|Clostridia,3WHDF@541000|Ruminococcaceae	186801|Clostridia	EG	spore germination protein	-	-	-	ko:K06295	-	-	-	-	ko00000	-	-	-	GerA
HALNLLBL_00473	1120746.CCNL01000012_gene1919	3.8e-75	234.0	COG2323@1|root,COG2323@2|Bacteria	2|Bacteria	K	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF421
HALNLLBL_00475	903814.ELI_0567	2.39e-108	322.0	COG1108@1|root,COG1108@2|Bacteria,1TR79@1239|Firmicutes,24875@186801|Clostridia,25V63@186806|Eubacteriaceae	186801|Clostridia	P	ABC 3 transport family	-	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
HALNLLBL_00476	1232453.BAIF02000051_gene964	2.92e-90	273.0	COG1121@1|root,COG1121@2|Bacteria,1TQ68@1239|Firmicutes,248F1@186801|Clostridia,268SH@186813|unclassified Clostridiales	186801|Clostridia	P	ABC transporter	-	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
HALNLLBL_00477	1292035.H476_2990	4.39e-93	287.0	COG0803@1|root,COG0803@2|Bacteria,1TPG7@1239|Firmicutes,249VZ@186801|Clostridia,25R39@186804|Peptostreptococcaceae	186801|Clostridia	P	Belongs to the bacterial solute-binding protein 9 family	adcA	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
HALNLLBL_00478	428125.CLOLEP_02702	1.55e-101	308.0	COG0341@1|root,COG0341@2|Bacteria,1TSZE@1239|Firmicutes,249A3@186801|Clostridia,3WGWX@541000|Ruminococcaceae	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
HALNLLBL_00479	1105031.HMPREF1141_2471	2.1e-167	487.0	COG0342@1|root,COG0342@2|Bacteria,1TQVT@1239|Firmicutes,247X8@186801|Clostridia,36DYW@31979|Clostridiaceae	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF
HALNLLBL_00480	428125.CLOLEP_02697	5.71e-196	556.0	COG1167@1|root,COG1167@2|Bacteria,1TPMY@1239|Firmicutes,24986@186801|Clostridia,3WGVJ@541000|Ruminococcaceae	186801|Clostridia	EK	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_MocR
HALNLLBL_00481	1301100.HG529225_gene4212	2.06e-41	148.0	COG0489@1|root,COG0489@2|Bacteria,1TS4R@1239|Firmicutes,24B0Z@186801|Clostridia,36DN2@31979|Clostridiaceae	186801|Clostridia	D	Capsular exopolysaccharide family	ywqD	-	-	-	-	-	-	-	-	-	-	-	AAA_31,ParA,Wzz
HALNLLBL_00482	553973.CLOHYLEM_05554	1.15e-10	67.8	COG3944@1|root,COG3944@2|Bacteria,1UZCR@1239|Firmicutes,24G4J@186801|Clostridia,21Y7C@1506553|Lachnoclostridium	186801|Clostridia	M	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzz
HALNLLBL_00483	1120746.CCNL01000010_gene1410	1.78e-200	565.0	COG1883@1|root,COG1883@2|Bacteria,2NP19@2323|unclassified Bacteria	2|Bacteria	C	Na+-transporting oxaloacetate decarboxylase beta subunit	gcdB	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
HALNLLBL_00485	428125.CLOLEP_02350	1.01e-243	682.0	COG5019@1|root,COG5019@2|Bacteria,1UHVS@1239|Firmicutes,25E4Q@186801|Clostridia,3WGJE@541000|Ruminococcaceae	186801|Clostridia	DZ	ATPase. Has a role at an early stage in the morphogenesis of the spore coat	spoIVA	-	-	ko:K06398	-	-	-	-	ko00000	-	-	-	Spore_IV_A
HALNLLBL_00486	1105031.HMPREF1141_3016	4.57e-101	320.0	COG1388@1|root,COG1388@2|Bacteria,1TSVC@1239|Firmicutes,248VQ@186801|Clostridia,36EW2@31979|Clostridiaceae	186801|Clostridia	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3794,LysM
HALNLLBL_00487	1120746.CCNL01000011_gene1772	1.48e-140	407.0	COG0564@1|root,COG0564@2|Bacteria,2NNY5@2323|unclassified Bacteria	2|Bacteria	J	Responsible for synthesis of pseudouridine from uracil	rluC	-	5.4.99.23,5.4.99.24	ko:K06179,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
HALNLLBL_00488	428125.CLOLEP_01578	1.68e-113	335.0	COG1496@1|root,COG1496@2|Bacteria,1TS34@1239|Firmicutes,248TD@186801|Clostridia,3WHV2@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the multicopper oxidase YfiH RL5 family	yfiH	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
HALNLLBL_00490	1235835.C814_00101	2.13e-84	253.0	COG0221@1|root,COG0221@2|Bacteria,1V2DF@1239|Firmicutes,24G1A@186801|Clostridia,3WI3Y@541000|Ruminococcaceae	186801|Clostridia	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
HALNLLBL_00491	411902.CLOBOL_04443	0.0	1134.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia,21XE0@1506553|Lachnoclostridium	186801|Clostridia	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
HALNLLBL_00493	1235835.C814_02088	1.48e-124	363.0	COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,248RY@186801|Clostridia,3WGWE@541000|Ruminococcaceae	186801|Clostridia	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
HALNLLBL_00494	1120746.CCNL01000011_gene1609	9.51e-156	454.0	COG0144@1|root,COG3270@1|root,COG0144@2|Bacteria,COG3270@2|Bacteria,2NPE2@2323|unclassified Bacteria	2|Bacteria	J	N-terminal domain of 16S rRNA methyltransferase RsmF	rsmF	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176,2.1.1.178	ko:K03500,ko:K11392	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA,RsmF_methylt_CI
HALNLLBL_00496	428125.CLOLEP_01590	5.53e-78	240.0	COG1139@1|root,COG1139@2|Bacteria,1TP90@1239|Firmicutes,249B6@186801|Clostridia,3WIFU@541000|Ruminococcaceae	186801|Clostridia	C	LUD domain	-	-	-	-	-	-	-	-	-	-	-	-	LUD_dom
HALNLLBL_00497	428125.CLOLEP_01588	1.74e-83	253.0	COG0860@1|root,COG3103@1|root,COG0860@2|Bacteria,COG3103@2|Bacteria,1TQ50@1239|Firmicutes,249IF@186801|Clostridia,3WIH3@541000|Ruminococcaceae	186801|Clostridia	MT	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,SH3_3,SPOR
HALNLLBL_00498	1408311.JNJM01000023_gene125	7.84e-81	243.0	COG2816@1|root,COG2816@2|Bacteria,1V6WC@1239|Firmicutes,25B2M@186801|Clostridia,2PS6V@265975|Oribacterium	186801|Clostridia	L	NUDIX domain	-	-	3.6.1.22	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	-	R00103,R03004,R11104	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
HALNLLBL_00499	411467.BACCAP_01603	1.91e-137	407.0	COG1134@1|root,COG1134@2|Bacteria,1TQKK@1239|Firmicutes,24A5V@186801|Clostridia,26AB7@186813|unclassified Clostridiales	186801|Clostridia	GM	ATPases associated with a variety of cellular activities	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
HALNLLBL_00500	926569.ANT_26220	5.49e-94	286.0	COG1682@1|root,COG1682@2|Bacteria	2|Bacteria	GM	macromolecule localization	wzm	-	-	ko:K01992,ko:K09690	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC2_membrane
HALNLLBL_00501	1408324.JNJK01000013_gene53	9.95e-83	252.0	COG0652@1|root,COG0652@2|Bacteria,1V1SP@1239|Firmicutes,24G4H@186801|Clostridia,27MJD@186928|unclassified Lachnospiraceae	186801|Clostridia	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Pro_isomerase
HALNLLBL_00502	1163671.JAGI01000002_gene2387	2.54e-65	204.0	COG1671@1|root,COG1671@2|Bacteria,1V9Z0@1239|Firmicutes,24HPW@186801|Clostridia,36J4K@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the UPF0178 family	-	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
HALNLLBL_00503	552398.HMPREF0866_02539	9.73e-131	389.0	COG1472@1|root,COG1472@2|Bacteria,1TP63@1239|Firmicutes,24YIP@186801|Clostridia,3WG7U@541000|Ruminococcaceae	186801|Clostridia	G	Hydrolase Family 3	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
HALNLLBL_00504	180332.JTGN01000007_gene3588	1.5e-06	60.5	COG2304@1|root,COG3942@1|root,COG5492@1|root,COG2304@2|Bacteria,COG3942@2|Bacteria,COG5492@2|Bacteria,1VKTN@1239|Firmicutes,24WKA@186801|Clostridia	186801|Clostridia	KLT	C-type lectin (CTL) or carbohydrate-recognition domain (CRD)	-	-	-	-	-	-	-	-	-	-	-	-	Lectin_C
HALNLLBL_00505	1232449.BAHV02000008_gene601	3.92e-45	152.0	COG1329@1|root,COG1329@2|Bacteria,1V7IF@1239|Firmicutes,25CYY@186801|Clostridia	186801|Clostridia	K	CarD-like/TRCF domain	-	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
HALNLLBL_00506	397290.C810_02057	8.75e-195	550.0	COG0426@1|root,COG0426@2|Bacteria,1TQE9@1239|Firmicutes,249CU@186801|Clostridia,27I60@186928|unclassified Lachnospiraceae	186801|Clostridia	C	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1,Flavodoxin_5,Lactamase_B
HALNLLBL_00507	1235793.C809_03093	3.29e-29	106.0	COG2026@1|root,COG2026@2|Bacteria,1VCRD@1239|Firmicutes,25K0W@186801|Clostridia,27Q6W@186928|unclassified Lachnospiraceae	186801|Clostridia	DJ	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
HALNLLBL_00508	411483.FAEPRAA2165_00683	2.1e-19	80.9	2CBNP@1|root,33J1I@2|Bacteria,1VP33@1239|Firmicutes,24WEX@186801|Clostridia,3WQQK@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_00509	1105031.HMPREF1141_1862	0.0	1135.0	COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia,36DDN@31979|Clostridiaceae	186801|Clostridia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
HALNLLBL_00510	428125.CLOLEP_01061	1.78e-47	152.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,3WK6U@541000|Ruminococcaceae	186801|Clostridia	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
HALNLLBL_00511	1105031.HMPREF1141_0292	3.16e-08	56.2	COG1476@1|root,COG1476@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
HALNLLBL_00513	1105031.HMPREF1141_3054	2.06e-10	68.6	COG5578@1|root,COG5578@2|Bacteria,1V87X@1239|Firmicutes,24PJA@186801|Clostridia	186801|Clostridia	S	Protein of unknown function, DUF624	-	-	-	-	-	-	-	-	-	-	-	-	DUF624
HALNLLBL_00514	665956.HMPREF1032_01809	3.31e-201	571.0	COG1653@1|root,COG1653@2|Bacteria,1TQHT@1239|Firmicutes,249J6@186801|Clostridia,3WICE@541000|Ruminococcaceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	amyE	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_8,TAT_signal
HALNLLBL_00515	1519439.JPJG01000014_gene107	2.52e-126	369.0	COG1175@1|root,COG1175@2|Bacteria,1TP1Q@1239|Firmicutes,24ADV@186801|Clostridia,2N8XU@216572|Oscillospiraceae	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
HALNLLBL_00516	411463.EUBVEN_02432	1.55e-120	354.0	COG0395@1|root,COG0395@2|Bacteria,1TR45@1239|Firmicutes,24A48@186801|Clostridia,25UYF@186806|Eubacteriaceae	186801|Clostridia	P	sugar transport system permease	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
HALNLLBL_00517	428125.CLOLEP_02998	0.0	963.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,2486F@186801|Clostridia,3WGI2@541000|Ruminococcaceae	186801|Clostridia	O	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03697	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small
HALNLLBL_00518	1105031.HMPREF1141_3516	5.1e-42	147.0	COG0558@1|root,COG0558@2|Bacteria,1V4YR@1239|Firmicutes,24FWZ@186801|Clostridia,36VDN@31979|Clostridiaceae	186801|Clostridia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.41	ko:K08744	ko00564,ko01100,map00564,map01100	-	R02030	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
HALNLLBL_00521	428125.CLOLEP_02995	1.64e-126	366.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,248W2@186801|Clostridia,3WIKF@541000|Ruminococcaceae	186801|Clostridia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
HALNLLBL_00522	428125.CLOLEP_02994	9.07e-101	301.0	COG0619@1|root,COG0619@2|Bacteria,1TQ0E@1239|Firmicutes,248AB@186801|Clostridia,3WGYM@541000|Ruminococcaceae	186801|Clostridia	P	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfT	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
HALNLLBL_00523	428125.CLOLEP_02993	1.89e-135	391.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia,3WG8V@541000|Ruminococcaceae	186801|Clostridia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	cbiO	-	-	ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
HALNLLBL_00524	428125.CLOLEP_02992	1.09e-138	399.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia,3WG9K@541000|Ruminococcaceae	186801|Clostridia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
HALNLLBL_00525	1120746.CCNL01000008_gene588	4.36e-170	479.0	COG1092@1|root,COG1092@2|Bacteria	2|Bacteria	J	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
HALNLLBL_00526	428125.CLOLEP_02990	4.03e-212	598.0	COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,2499P@186801|Clostridia,3WGDW@541000|Ruminococcaceae	186801|Clostridia	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
HALNLLBL_00527	428125.CLOLEP_02989	2.52e-199	558.0	COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,247W0@186801|Clostridia,3WGXE@541000|Ruminococcaceae	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
HALNLLBL_00528	1105031.HMPREF1141_3526	3.39e-63	201.0	COG0632@1|root,COG0632@2|Bacteria,1V3KF@1239|Firmicutes,24JKV@186801|Clostridia,36IEQ@31979|Clostridiaceae	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
HALNLLBL_00529	428125.CLOLEP_02987	2.42e-79	239.0	COG0817@1|root,COG0817@2|Bacteria,1V3N9@1239|Firmicutes,24HMI@186801|Clostridia,3WIS5@541000|Ruminococcaceae	186801|Clostridia	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
HALNLLBL_00533	537013.CLOSTMETH_00841	2.79e-218	623.0	COG0366@1|root,COG4728@1|root,COG0366@2|Bacteria,COG4728@2|Bacteria,1TQFJ@1239|Firmicutes,249Y3@186801|Clostridia,3WGMX@541000|Ruminococcaceae	186801|Clostridia	G	Alpha amylase, catalytic domain protein	-	-	3.2.1.133,3.2.1.135,3.2.1.54,3.5.4.33	ko:K01208,ko:K11991	ko00500,ko01100,map00500,map01100	-	R02112,R03122,R10223,R11262	RC00477	ko00000,ko00001,ko01000,ko03016	-	GH13	-	Alpha-amylase,Alpha-amylase_C,DUF1653,Malt_amylase_C
HALNLLBL_00534	1235793.C809_00466	0.0	946.0	COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,2481P@186801|Clostridia,27J01@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Alpha amylase, catalytic domain	glgX	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
HALNLLBL_00537	1121289.JHVL01000010_gene1325	7.25e-72	226.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia,36RTF@31979|Clostridiaceae	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HALNLLBL_00540	537013.CLOSTMETH_01392	4.68e-36	147.0	2CZ00@1|root,32T59@2|Bacteria,1VJ9C@1239|Firmicutes,24NTD@186801|Clostridia,3WPP0@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_00541	622312.ROSEINA2194_02866	9.03e-27	103.0	COG0745@1|root,COG0745@2|Bacteria,1TPU2@1239|Firmicutes,24B71@186801|Clostridia	186801|Clostridia	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	dltR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HALNLLBL_00542	1384065.JAGS01000001_gene1391	1.19e-34	126.0	COG0745@1|root,COG0745@2|Bacteria,1TPU2@1239|Firmicutes,24B71@186801|Clostridia,3WGHT@541000|Ruminococcaceae	186801|Clostridia	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	dltR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HALNLLBL_00546	861454.HMPREF9099_00507	2.15e-116	339.0	COG0639@1|root,COG0639@2|Bacteria,1V1HN@1239|Firmicutes,24G1E@186801|Clostridia,27M10@186928|unclassified Lachnospiraceae	186801|Clostridia	T	Calcineurin-like phosphoesterase	-	-	3.1.3.16	ko:K07313	-	-	-	-	ko00000,ko01000	-	-	-	Metallophos
HALNLLBL_00547	411463.EUBVEN_02483	4.52e-21	84.7	COG4186@1|root,COG4186@2|Bacteria,1V6DG@1239|Firmicutes,24JMS@186801|Clostridia	186801|Clostridia	S	Phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
HALNLLBL_00548	1514668.JOOA01000002_gene886	8.48e-74	224.0	COG0394@1|root,COG0394@2|Bacteria,1V6SG@1239|Firmicutes,24MMZ@186801|Clostridia,3WIXC@541000|Ruminococcaceae	186801|Clostridia	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	yfkJ	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
HALNLLBL_00549	1232449.BAHV02000018_gene1627	1.32e-26	108.0	COG1309@1|root,COG1309@2|Bacteria,1V6CF@1239|Firmicutes,25BKD@186801|Clostridia,26CPB@186813|unclassified Clostridiales	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HALNLLBL_00550	445971.ANASTE_00408	0.0	961.0	COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,2491S@186801|Clostridia,25V9F@186806|Eubacteriaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 10.00	czcA	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
HALNLLBL_00551	411469.EUBHAL_00036	1.23e-73	225.0	COG2606@1|root,COG2606@2|Bacteria,1V6JF@1239|Firmicutes,24I4E@186801|Clostridia,25WMS@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily	ybaK	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
HALNLLBL_00553	742735.HMPREF9467_01607	1.48e-154	468.0	COG1269@1|root,COG1269@2|Bacteria,1TPTE@1239|Firmicutes,249YV@186801|Clostridia,21YR6@1506553|Lachnoclostridium	186801|Clostridia	C	Belongs to the V-ATPase 116 kDa subunit family	ntpI	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
HALNLLBL_00554	1151292.QEW_3577	5.39e-38	134.0	COG0636@1|root,COG0636@2|Bacteria,1V786@1239|Firmicutes,24HBF@186801|Clostridia,25TT6@186804|Peptostreptococcaceae	186801|Clostridia	C	ATP synthase subunit C	ntpK	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
HALNLLBL_00557	1232443.BAIA02000097_gene3411	1.72e-31	114.0	COG1436@1|root,COG1436@2|Bacteria,1VAX7@1239|Firmicutes,24MXC@186801|Clostridia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpF	-	-	ko:K02122	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_F
HALNLLBL_00558	1235835.C814_00049	0.0	877.0	COG1155@1|root,COG1155@2|Bacteria,1TPGS@1239|Firmicutes,24882@186801|Clostridia,3WGBK@541000|Ruminococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit	ntpA	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
HALNLLBL_00559	1232443.BAIA02000097_gene3413	1.07e-288	793.0	COG1156@1|root,COG1156@2|Bacteria,1VSU1@1239|Firmicutes,2496H@186801|Clostridia,267RU@186813|unclassified Clostridiales	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	atpB	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
HALNLLBL_00560	411902.CLOBOL_04981	1.33e-93	280.0	COG1394@1|root,COG1394@2|Bacteria,1TQ1Y@1239|Firmicutes,247TC@186801|Clostridia,21XKD@1506553|Lachnoclostridium	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpD	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
HALNLLBL_00561	1341157.RF007C_12595	9.7e-46	155.0	COG0454@1|root,COG0456@2|Bacteria,1VEW7@1239|Firmicutes,24RBJ@186801|Clostridia,3WJBB@541000|Ruminococcaceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	nnrE	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7,YjeF_N
HALNLLBL_00562	537007.BLAHAN_07107	7.79e-111	341.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3XZQ9@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HALNLLBL_00563	1160721.RBI_I01135	4.65e-279	766.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,3WGBH@541000|Ruminococcaceae	186801|Clostridia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
HALNLLBL_00564	1499683.CCFF01000017_gene1562	2.31e-34	119.0	COG0640@1|root,COG0640@2|Bacteria,1VA3M@1239|Firmicutes,24NEC@186801|Clostridia,36KQM@31979|Clostridiaceae	186801|Clostridia	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
HALNLLBL_00565	511680.BUTYVIB_01772	1.61e-30	119.0	COG5658@1|root,COG5658@2|Bacteria,1VBIT@1239|Firmicutes,24PFZ@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1648,SdpI
HALNLLBL_00566	1160721.RBI_I00794	5.95e-317	885.0	COG2217@1|root,COG2217@2|Bacteria,1TPB8@1239|Firmicutes,247RZ@186801|Clostridia,3WHGR@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	copA_1	-	-	ko:K12950	-	-	-	-	ko00000,ko01000	3.A.3.32	-	-	E1-E2_ATPase,Hydrolase
HALNLLBL_00567	1160721.RBI_I00795	1.07e-33	117.0	2EGCF@1|root,33A48@2|Bacteria,1TV0R@1239|Firmicutes,2586M@186801|Clostridia,3WM1Y@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_00568	1232453.BAIF02000102_gene3647	7.47e-122	355.0	COG0428@1|root,COG0428@2|Bacteria,1TP7J@1239|Firmicutes,247Q2@186801|Clostridia,268BU@186813|unclassified Clostridiales	186801|Clostridia	P	ZIP Zinc transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
HALNLLBL_00569	1131462.DCF50_p716	4.28e-109	372.0	COG0419@1|root,COG0419@2|Bacteria,1TPCS@1239|Firmicutes,24A22@186801|Clostridia,260UM@186807|Peptococcaceae	186801|Clostridia	L	Putative exonuclease SbcCD, C subunit	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,AAA_29,SbcCD_C
HALNLLBL_00570	411474.COPEUT_00675	1.47e-102	315.0	COG0420@1|root,COG0420@2|Bacteria,1TQY6@1239|Firmicutes,248VE@186801|Clostridia	186801|Clostridia	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,SbcD_C
HALNLLBL_00571	657322.FPR_30870	1.65e-38	131.0	2CCD5@1|root,32RVD@2|Bacteria,1UPQI@1239|Firmicutes,25HM0@186801|Clostridia,3WREV@541000|Ruminococcaceae	186801|Clostridia	S	Branched-chain amino acid transport protein (AzlD)	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
HALNLLBL_00572	1121423.JONT01000011_gene178	5.43e-105	311.0	COG1296@1|root,COG1296@2|Bacteria,1TSXD@1239|Firmicutes,24CRN@186801|Clostridia,2650R@186807|Peptococcaceae	186801|Clostridia	E	branched-chain amino acid permease (Azaleucine resistance)	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
HALNLLBL_00575	410358.Mlab_1452	1.46e-22	99.8	COG2172@1|root,arCOG06892@2157|Archaea	2157|Archaea	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2
HALNLLBL_00576	1408324.JNJK01000004_gene2756	1.21e-21	88.6	COG1366@1|root,COG1366@2|Bacteria,1VB77@1239|Firmicutes,24NE7@186801|Clostridia,27NXD@186928|unclassified Lachnospiraceae	186801|Clostridia	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS,STAS_2
HALNLLBL_00577	386456.JQKN01000009_gene1214	1.39e-101	326.0	COG0534@1|root,COG2172@1|root,arCOG01732@2157|Archaea,arCOG06892@2157|Archaea,2XVF5@28890|Euryarchaeota,23PHB@183925|Methanobacteria	183925|Methanobacteria	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HALNLLBL_00578	97139.C824_00379	0.0	2194.0	COG1020@1|root,COG3320@1|root,COG1020@2|Bacteria,COG3320@2|Bacteria,1TPTH@1239|Firmicutes,2490U@186801|Clostridia,36EG3@31979|Clostridiaceae	186801|Clostridia	Q	TIGRFAM amino acid adenylation domain	-	-	6.1.1.13	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	M00725	R02718	RC00037,RC00094	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	AMP-binding,AMP-binding_C,Condensation,NAD_binding_4,PP-binding
HALNLLBL_00579	1002809.SSIL_3198	3.88e-12	68.2	COG4767@1|root,COG4767@2|Bacteria,1VAH6@1239|Firmicutes,4HN8M@91061|Bacilli,26FXF@186818|Planococcaceae	91061|Bacilli	V	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
HALNLLBL_00580	246199.CUS_6290	1.49e-48	166.0	COG3279@1|root,COG3279@2|Bacteria,1TSDB@1239|Firmicutes,24MQ4@186801|Clostridia,3WKJJ@541000|Ruminococcaceae	186801|Clostridia	K	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
HALNLLBL_00581	272563.CD630_05760	5.03e-09	66.6	COG0642@1|root,COG0642@2|Bacteria,1V7G1@1239|Firmicutes,25ER0@186801|Clostridia	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
HALNLLBL_00582	1256908.HMPREF0373_01622	2.55e-81	245.0	COG0350@1|root,COG0350@2|Bacteria,1V2MB@1239|Firmicutes,24HJ0@186801|Clostridia,25W3N@186806|Eubacteriaceae	186801|Clostridia	H	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	-	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
HALNLLBL_00584	1188235.MBVG_3880	1.76e-22	88.2	COG2314@1|root,COG2314@2|Bacteria,3WU5Y@544448|Tenericutes	544448|Tenericutes	S	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	TM2
HALNLLBL_00585	411473.RUMCAL_01843	4.27e-304	841.0	COG2895@1|root,COG2895@2|Bacteria,1UI8R@1239|Firmicutes,249BX@186801|Clostridia,3WSPE@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
HALNLLBL_00586	411473.RUMCAL_01842	1.4e-204	567.0	COG0175@1|root,COG0175@2|Bacteria,1U1VN@1239|Firmicutes,248Y9@186801|Clostridia,3WJJK@541000|Ruminococcaceae	186801|Clostridia	EH	PFAM Phosphoadenosine phosphosulfate reductase	cysD	-	1.8.4.10,1.8.4.8,2.7.7.4	ko:K00390,ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R02021,R04929	RC00007,RC02809,RC02862,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
HALNLLBL_00587	59374.Fisuc_0145	1.94e-52	166.0	COG1146@1|root,COG1146@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	-	-	1.8.99.2	ko:K00395	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_10,Fer4_4,Fer4_9
HALNLLBL_00588	411473.RUMCAL_01840	9.15e-314	865.0	COG1053@1|root,COG1053@2|Bacteria,1TRE8@1239|Firmicutes,247TH@186801|Clostridia,3WNS7@541000|Ruminococcaceae	186801|Clostridia	C	Fumarate reductase flavoprotein C-term	aprA	-	1.8.99.2	ko:K00394	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
HALNLLBL_00589	411473.RUMCAL_01839	7.78e-110	327.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,3WHUP@541000|Ruminococcaceae	186801|Clostridia	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Thioredoxin
HALNLLBL_00590	411473.RUMCAL_01838	1.23e-77	233.0	COG1310@1|root,COG1310@2|Bacteria,1V6TY@1239|Firmicutes,24JI8@186801|Clostridia,3WJ1M@541000|Ruminococcaceae	186801|Clostridia	S	Mov34 MPN PAD-1 family	-	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
HALNLLBL_00591	1160721.RBI_I01805	5.77e-178	497.0	COG0476@1|root,COG0476@2|Bacteria,1TQ3U@1239|Firmicutes,25CJC@186801|Clostridia,3WGRI@541000|Ruminococcaceae	186801|Clostridia	H	PFAM UBA THIF-type NAD FAD binding protein	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
HALNLLBL_00592	1160721.RBI_I01806	4.36e-35	120.0	COG2104@1|root,COG2104@2|Bacteria,1VFJR@1239|Firmicutes,24SEU@186801|Clostridia,3WKGM@541000|Ruminococcaceae	186801|Clostridia	H	TIGRFAM thiamine biosynthesis protein ThiS	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
HALNLLBL_00593	411473.RUMCAL_01835	8.64e-41	137.0	COG0526@1|root,COG0526@2|Bacteria,1UG1U@1239|Firmicutes,24SF7@186801|Clostridia,3WKHR@541000|Ruminococcaceae	186801|Clostridia	O	Thioredoxin-like domain	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
HALNLLBL_00594	1160721.RBI_I01808	4.73e-47	151.0	COG0425@1|root,COG0425@2|Bacteria,1VBET@1239|Firmicutes,24NV0@186801|Clostridia,3WJTK@541000|Ruminococcaceae	186801|Clostridia	O	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	TusA
HALNLLBL_00595	1160721.RBI_I01809	4.39e-172	484.0	COG2221@1|root,COG2221@2|Bacteria,1TR7P@1239|Firmicutes,2493K@186801|Clostridia,3WHZF@541000|Ruminococcaceae	186801|Clostridia	C	PFAM nitrite and sulphite reductase 4Fe-4S	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,NIR_SIR,NIR_SIR_ferr
HALNLLBL_00596	1160721.RBI_I01810	1.35e-224	627.0	COG2873@1|root,COG2873@2|Bacteria,1TXZ1@1239|Firmicutes,248M7@186801|Clostridia,3WH3A@541000|Ruminococcaceae	186801|Clostridia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
HALNLLBL_00597	1384065.JAGS01000001_gene1529	3.16e-36	129.0	COG1959@1|root,COG1959@2|Bacteria,1V6RP@1239|Firmicutes,24KGB@186801|Clostridia,3WKDJ@541000|Ruminococcaceae	186801|Clostridia	K	transcriptional regulator, Rrf2 family	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
HALNLLBL_00598	1160721.RBI_I00187	9.95e-217	608.0	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,248II@186801|Clostridia,3WGHS@541000|Ruminococcaceae	186801|Clostridia	H	PFAM Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
HALNLLBL_00599	1160721.RBI_I00188	1.69e-168	477.0	COG0113@1|root,COG0113@2|Bacteria,1TP09@1239|Firmicutes,2496V@186801|Clostridia,3WGUW@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS15750	ALAD
HALNLLBL_00600	1160721.RBI_I00189	4.2e-159	467.0	COG0007@1|root,COG0007@2|Bacteria,1TQNH@1239|Firmicutes,2487I@186801|Clostridia,3WHWX@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the precorrin methyltransferase family	cobA	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS15755	HEM4,Porphobil_deam,Porphobil_deamC,TP_methylase
HALNLLBL_00601	1160721.RBI_I00190	1.05e-89	275.0	COG0181@1|root,COG0181@2|Bacteria,1TPFQ@1239|Firmicutes,2494Z@186801|Clostridia,3WG89@541000|Ruminococcaceae	186801|Clostridia	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
HALNLLBL_00602	1160721.RBI_I00191	7.37e-44	152.0	COG1648@1|root,COG1648@2|Bacteria,1VA2E@1239|Firmicutes,24N6M@186801|Clostridia,3WKZJ@541000|Ruminococcaceae	186801|Clostridia	H	Putative NAD(P)-binding	cysG	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M
HALNLLBL_00603	610130.Closa_3083	1.96e-102	315.0	COG0373@1|root,COG0373@2|Bacteria,1TQN9@1239|Firmicutes,2496M@186801|Clostridia,220JE@1506553|Lachnoclostridium	186801|Clostridia	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
HALNLLBL_00604	1392491.JIAE01000001_gene1839	1.03e-139	399.0	COG1179@1|root,COG1179@2|Bacteria,1TQ7A@1239|Firmicutes,248RA@186801|Clostridia,3WG8S@541000|Ruminococcaceae	186801|Clostridia	H	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1	thiF	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
HALNLLBL_00605	1514668.JOOA01000001_gene692	2.61e-61	196.0	COG4185@1|root,COG4185@2|Bacteria,1V42Y@1239|Firmicutes,24A28@186801|Clostridia,3WIQX@541000|Ruminococcaceae	186801|Clostridia	S	zeta toxin	-	-	-	-	-	-	-	-	-	-	-	-	Zeta_toxin
HALNLLBL_00606	59374.Fisuc_0152	2.76e-180	510.0	COG3842@1|root,COG3842@2|Bacteria	2|Bacteria	P	ATPase activity	cysA	-	3.6.3.25	ko:K02045	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	ABC_tran,TOBE_2,TOBE_3
HALNLLBL_00607	59374.Fisuc_0151	2.03e-145	415.0	COG4208@1|root,COG4208@2|Bacteria	2|Bacteria	P	ATPase-coupled sulfate transmembrane transporter activity	cysW	-	-	ko:K02047	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
HALNLLBL_00608	411473.RUMCAL_00438	2.32e-150	428.0	COG0555@1|root,COG0555@2|Bacteria,1TQHR@1239|Firmicutes,24ACM@186801|Clostridia,3WIAX@541000|Ruminococcaceae	186801|Clostridia	P	Sulfate ABC transporter, permease protein CysT	cysT	-	-	ko:K02046,ko:K15496	ko00920,ko02010,map00920,map02010	M00185,M00423	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3,3.A.1.6.5	-	-	BPD_transp_1
HALNLLBL_00609	411473.RUMCAL_00439	1.23e-189	533.0	COG1613@1|root,COG1613@2|Bacteria,1TS25@1239|Firmicutes,24B9S@186801|Clostridia,3WGXR@541000|Ruminococcaceae	186801|Clostridia	P	Extracellular solute-binding protein	sbp	-	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	SBP_bac_11
HALNLLBL_00610	411470.RUMGNA_03389	5.79e-111	320.0	COG1592@1|root,COG1592@2|Bacteria,1V1FF@1239|Firmicutes,248V2@186801|Clostridia,3XZBD@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	rbr	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct,Rubrerythrin
HALNLLBL_00611	500633.CLOHIR_01481	1.82e-185	521.0	COG0673@1|root,COG0673@2|Bacteria,1TPT5@1239|Firmicutes,248MV@186801|Clostridia,25T34@186804|Peptostreptococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
HALNLLBL_00612	411463.EUBVEN_00894	3.65e-183	526.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,25VAA@186806|Eubacteriaceae	186801|Clostridia	V	CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HALNLLBL_00613	1280698.AUJS01000006_gene2864	9.54e-98	305.0	COG0038@1|root,COG0038@2|Bacteria,1UZ4F@1239|Firmicutes,24921@186801|Clostridia	186801|Clostridia	P	Voltage gated chloride channel	-	-	-	-	-	-	-	-	-	-	-	-	Voltage_CLC
HALNLLBL_00614	33035.JPJF01000133_gene4526	1.18e-62	195.0	COG1266@1|root,COG1266@2|Bacteria,1TRT7@1239|Firmicutes,24DRE@186801|Clostridia	186801|Clostridia	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
HALNLLBL_00615	1121333.JMLH01000046_gene956	9.9e-97	284.0	COG1670@1|root,COG1670@2|Bacteria,1V6E0@1239|Firmicutes,3VQWF@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
HALNLLBL_00616	1504822.CCNO01000011_gene176	1.18e-197	560.0	COG0366@1|root,COG0366@2|Bacteria,2NPAG@2323|unclassified Bacteria	2|Bacteria	G	PFAM Alpha amylase, catalytic	malS	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
HALNLLBL_00617	556261.HMPREF0240_01392	1.86e-120	348.0	COG0655@1|root,COG0655@2|Bacteria,1UI36@1239|Firmicutes,247R8@186801|Clostridia,36HCH@31979|Clostridiaceae	186801|Clostridia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
HALNLLBL_00618	515622.bpr_IV094	5.38e-12	62.4	COG3077@1|root,COG3077@2|Bacteria,1VEDW@1239|Firmicutes,24QJN@186801|Clostridia,4C0GR@830|Butyrivibrio	186801|Clostridia	L	RelB antitoxin	-	-	-	ko:K07473	-	-	-	-	ko00000,ko02048	-	-	-	RelB
HALNLLBL_00619	411473.RUMCAL_00791	2.52e-258	712.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3WHK1@541000|Ruminococcaceae	186801|Clostridia	C	belongs to the iron- containing alcohol dehydrogenase family	adh	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
HALNLLBL_00620	1123288.SOV_6c02250	1.39e-25	110.0	COG0583@1|root,COG0583@2|Bacteria,1VD3Q@1239|Firmicutes,4H5EE@909932|Negativicutes	909932|Negativicutes	K	LysR substrate binding domain	-	-	-	ko:K09681	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
HALNLLBL_00621	1203606.HMPREF1526_03160	6.96e-170	488.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,36E5Q@31979|Clostridiaceae	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
HALNLLBL_00622	1123405.AUMM01000016_gene2465	3.68e-258	724.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HE02@91061|Bacilli	91061|Bacilli	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
HALNLLBL_00623	476272.RUMHYD_00231	7.21e-33	120.0	COG0824@1|root,COG0824@2|Bacteria,1VAGM@1239|Firmicutes,24NBX@186801|Clostridia,3Y0GI@572511|Blautia	186801|Clostridia	S	Thioesterase-like superfamily	FcbC	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
HALNLLBL_00624	411469.EUBHAL_00190	3.2e-51	165.0	COG0347@1|root,COG0347@2|Bacteria,1V9Z5@1239|Firmicutes,24MNA@186801|Clostridia,25X0F@186806|Eubacteriaceae	186801|Clostridia	K	Nitrogen regulatory protein P-II	glnB	-	-	ko:K04751,ko:K04752	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
HALNLLBL_00625	411473.RUMCAL_00859	7.47e-219	613.0	COG0004@1|root,COG0004@2|Bacteria,1TQYG@1239|Firmicutes,247W1@186801|Clostridia,3WGAK@541000|Ruminococcaceae	186801|Clostridia	U	Ammonium Transporter Family	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
HALNLLBL_00626	428125.CLOLEP_03967	1.15e-232	656.0	COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,248G8@186801|Clostridia,3WGE5@541000|Ruminococcaceae	186801|Clostridia	D	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
HALNLLBL_00627	1160721.RBI_II00643	4.48e-219	607.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae	186801|Clostridia	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
HALNLLBL_00628	428125.CLOLEP_00512	1.02e-279	787.0	COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,247WH@186801|Clostridia,3WGDM@541000|Ruminococcaceae	186801|Clostridia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
HALNLLBL_00629	428125.CLOLEP_00513	8.73e-193	546.0	COG0448@1|root,COG0448@2|Bacteria,1TNZW@1239|Firmicutes,24943@186801|Clostridia,3WGWG@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
HALNLLBL_00630	428125.CLOLEP_00514	1.51e-116	350.0	COG0448@1|root,COG0448@2|Bacteria,1TPZ3@1239|Firmicutes,2482Q@186801|Clostridia,3WGWM@541000|Ruminococcaceae	186801|Clostridia	G	Glucose-1-phosphate adenylyltransferase, GlgD subunit	glgD	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
HALNLLBL_00631	428125.CLOLEP_00515	8.07e-228	640.0	COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,248G1@186801|Clostridia,3WGRA@541000|Ruminococcaceae	186801|Clostridia	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
HALNLLBL_00632	1121335.Clst_2135	1.2e-23	99.4	COG3275@1|root,COG3275@2|Bacteria,1VB87@1239|Firmicutes,24UWN@186801|Clostridia,3WKXZ@541000|Ruminococcaceae	186801|Clostridia	T	Pfam:DUF3816	-	-	-	-	-	-	-	-	-	-	-	-	ECF-ribofla_trS,ECF_trnsprt
HALNLLBL_00633	411902.CLOBOL_02256	1.88e-67	213.0	COG3601@1|root,COG3601@2|Bacteria,1V4BW@1239|Firmicutes,24E4V@186801|Clostridia,21XRD@1506553|Lachnoclostridium	186801|Clostridia	U	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins	ribU	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
HALNLLBL_00634	272563.CD630_16850	2.24e-69	220.0	COG4912@1|root,COG4912@2|Bacteria,1TQII@1239|Firmicutes,248N8@186801|Clostridia,25RFD@186804|Peptostreptococcaceae	186801|Clostridia	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
HALNLLBL_00635	411465.PEPMIC_01366	1.62e-96	292.0	COG3475@1|root,COG3475@2|Bacteria,1TT6A@1239|Firmicutes,249J0@186801|Clostridia	186801|Clostridia	M	LicD family	-	-	-	ko:K07271	-	-	-	-	ko00000,ko01000	-	-	-	LicD
HALNLLBL_00636	500632.CLONEX_00174	1.94e-118	353.0	COG1215@1|root,COG1215@2|Bacteria,1U4ZW@1239|Firmicutes	1239|Firmicutes	M	group 2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HALNLLBL_00638	428125.CLOLEP_02572	3.48e-122	370.0	COG0624@1|root,COG0624@2|Bacteria,1TPEG@1239|Firmicutes,247SK@186801|Clostridia,3WHQP@541000|Ruminococcaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
HALNLLBL_00639	1105031.HMPREF1141_0986	1.17e-241	702.0	COG4485@1|root,COG4485@2|Bacteria,1TPVY@1239|Firmicutes,24C9R@186801|Clostridia,36VYV@31979|Clostridiaceae	186801|Clostridia	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
HALNLLBL_00640	1121334.KB911071_gene1988	7.62e-77	236.0	COG1896@1|root,COG1896@2|Bacteria,1TSDU@1239|Firmicutes,24FT8@186801|Clostridia,3WGMJ@541000|Ruminococcaceae	186801|Clostridia	S	PFAM metal-dependent phosphohydrolase HD sub domain	yfbR	-	3.1.3.89	ko:K07023,ko:K08722	ko00240,ko01100,map00240,map01100	-	R01569,R01664,R01968,R02088,R02102,R10776	RC00017	ko00000,ko00001,ko01000	-	-	-	HD_2,HD_3
HALNLLBL_00641	1410617.JHXH01000001_gene708	8.05e-45	169.0	COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,248RH@186801|Clostridia,3WGW9@541000|Ruminococcaceae	186801|Clostridia	K	Cell envelope-like function transcriptional attenuator common domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
HALNLLBL_00642	140626.JHWB01000009_gene1774	2.65e-54	192.0	COG1316@1|root,COG1316@2|Bacteria,1UY3P@1239|Firmicutes,24H37@186801|Clostridia	186801|Clostridia	K	Cell envelope-like function transcriptional attenuator common domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
HALNLLBL_00643	742818.HMPREF9451_00544	9.69e-59	196.0	COG4509@1|root,COG4509@2|Bacteria	2|Bacteria	S	Sortase family	srtB	-	3.4.22.70	ko:K08600	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
HALNLLBL_00645	1514668.JOOA01000002_gene968	3.62e-154	440.0	COG0379@1|root,COG0379@2|Bacteria,1TP6R@1239|Firmicutes,247IJ@186801|Clostridia,3WGEP@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12020	NadA
HALNLLBL_00646	457412.RSAG_02353	7.62e-167	476.0	COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,247YV@186801|Clostridia,3WGZU@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
HALNLLBL_00647	1499683.CCFF01000014_gene3594	2.99e-177	545.0	COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,2481P@186801|Clostridia,36E5I@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 13 family	pulA	-	3.2.1.41	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	-	R02111	-	ko00000,ko00001,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
HALNLLBL_00649	1120746.CCNL01000010_gene1373	7.54e-105	314.0	COG1313@1|root,COG1313@2|Bacteria,2NP6I@2323|unclassified Bacteria	2|Bacteria	C	Radical SAM superfamily	pflX	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
HALNLLBL_00650	428125.CLOLEP_00277	6.25e-83	246.0	COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia,3WIS1@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
HALNLLBL_00651	1120746.CCNL01000017_gene3292	1.56e-69	213.0	COG0102@1|root,COG0102@2|Bacteria,2NPCI@2323|unclassified Bacteria	2|Bacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
HALNLLBL_00652	1105031.HMPREF1141_2029	1.77e-30	114.0	COG0642@1|root,COG2205@2|Bacteria,1VNVZ@1239|Firmicutes	1239|Firmicutes	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	Usp
HALNLLBL_00656	697329.Rumal_2867	1.12e-133	389.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,3WHCD@541000|Ruminococcaceae	186801|Clostridia	GK	ROK family	glcK	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
HALNLLBL_00657	428125.CLOLEP_01281	4.84e-284	784.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia,3WGWJ@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
HALNLLBL_00659	585394.RHOM_02160	5.48e-29	109.0	2DNQ7@1|root,32YJ2@2|Bacteria,1VFJY@1239|Firmicutes,24S09@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2752
HALNLLBL_00660	585394.RHOM_02155	1.81e-25	99.4	COG4640@1|root,COG4640@2|Bacteria,1VB94@1239|Firmicutes,24N0R@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4234,zinc_ribbon_2
HALNLLBL_00661	483218.BACPEC_02253	5.64e-266	733.0	COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,2485M@186801|Clostridia,268DQ@186813|unclassified Clostridiales	186801|Clostridia	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
HALNLLBL_00662	428125.CLOLEP_01278	1.48e-106	318.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,249VV@186801|Clostridia,3WHV1@541000|Ruminococcaceae	186801|Clostridia	K	Belongs to the ParB family	spo0J	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
HALNLLBL_00663	1120746.CCNL01000007_gene454	1.14e-126	366.0	COG1192@1|root,COG1192@2|Bacteria,2NP2C@2323|unclassified Bacteria	2|Bacteria	D	Cobyrinic acid ac-diamide synthase	soj	GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
HALNLLBL_00664	428125.CLOLEP_01273	9.3e-95	287.0	COG1475@1|root,COG1475@2|Bacteria,1TP0I@1239|Firmicutes,2488X@186801|Clostridia,3WINS@541000|Ruminococcaceae	186801|Clostridia	K	Belongs to the ParB family	noc	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
HALNLLBL_00665	406124.ACPC01000022_gene4284	2.37e-84	258.0	COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,4HAAZ@91061|Bacilli,1ZAWG@1386|Bacillus	91061|Bacilli	J	Specifically methylates the N7 position of guanine in position 535 of 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
HALNLLBL_00666	428125.CLOLEP_01270	0.0	959.0	COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,247U2@186801|Clostridia,3WGGQ@541000|Ruminococcaceae	186801|Clostridia	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
HALNLLBL_00667	428125.CLOLEP_01269	2.73e-196	559.0	COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,248A9@186801|Clostridia,3WGHG@541000|Ruminococcaceae	186801|Clostridia	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
HALNLLBL_00668	428125.CLOLEP_01268	5.94e-92	280.0	COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,249EA@186801|Clostridia,3WHR4@541000|Ruminococcaceae	186801|Clostridia	S	R3H domain protein	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
HALNLLBL_00669	428125.CLOLEP_01267	6.39e-80	254.0	COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,247V9@186801|Clostridia,3WHYT@541000|Ruminococcaceae	186801|Clostridia	U	Membrane protein insertase, YidC Oxa1 family	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
HALNLLBL_00670	428125.CLOLEP_01266	2.43e-35	121.0	COG0759@1|root,COG0759@2|Bacteria,1VEIG@1239|Firmicutes,24QN4@186801|Clostridia,3WKGN@541000|Ruminococcaceae	186801|Clostridia	S	Could be involved in insertion of integral membrane proteins into the membrane	yidD	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
HALNLLBL_00671	428125.CLOLEP_01265	3.37e-39	134.0	COG0594@1|root,COG0594@2|Bacteria,1VA78@1239|Firmicutes,24QK5@186801|Clostridia,3WKGV@541000|Ruminococcaceae	186801|Clostridia	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
HALNLLBL_00672	1105031.HMPREF1141_2304	9.02e-18	74.7	COG0230@1|root,COG0230@2|Bacteria,1VK90@1239|Firmicutes,24UGN@186801|Clostridia,36P8G@31979|Clostridiaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
HALNLLBL_00673	428125.CLOLEP_01262	1.67e-192	548.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,2490S@186801|Clostridia,3WGJH@541000|Ruminococcaceae	186801|Clostridia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
HALNLLBL_00674	428125.CLOLEP_01258	5.79e-135	399.0	COG0592@1|root,COG0592@2|Bacteria,1TQ7J@1239|Firmicutes,248EG@186801|Clostridia,3WGZ2@541000|Ruminococcaceae	186801|Clostridia	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
HALNLLBL_00675	1120746.CCNL01000007_gene443	5.1e-24	92.4	COG2501@1|root,COG2501@2|Bacteria	2|Bacteria	S	S4 domain	yaaA	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K14761	-	-	-	-	ko00000,ko03009	-	-	-	S4_2
HALNLLBL_00676	428125.CLOLEP_01256	7.57e-120	358.0	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,247KY@186801|Clostridia,3WHXU@541000|Ruminococcaceae	186801|Clostridia	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
HALNLLBL_00677	428125.CLOLEP_01255	1.58e-31	113.0	2E36Q@1|root,32Y6E@2|Bacteria,1VEZV@1239|Firmicutes,24MQP@186801|Clostridia,3WKJK@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF370)	-	-	-	-	-	-	-	-	-	-	-	-	DUF370
HALNLLBL_00679	428125.CLOLEP_01253	0.0	996.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,248AV@186801|Clostridia,3WGZ0@541000|Ruminococcaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
HALNLLBL_00680	428125.CLOLEP_01251	3.21e-39	136.0	COG0824@1|root,COG0824@2|Bacteria,1VAGM@1239|Firmicutes,24NBX@186801|Clostridia,3WJ96@541000|Ruminococcaceae	186801|Clostridia	S	acyl-CoA thioester hydrolase	FcbC	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
HALNLLBL_00681	428125.CLOLEP_01250	0.0	1073.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,2482G@186801|Clostridia,3WGW0@541000|Ruminococcaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
HALNLLBL_00683	471875.RUMLAC_00727	4.36e-91	311.0	29URU@1|root,30G3W@2|Bacteria,1UF59@1239|Firmicutes,25K62@186801|Clostridia,3WP2M@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_00684	1160721.RBI_I00554	2.09e-220	629.0	COG2197@1|root,COG2197@2|Bacteria,1U63E@1239|Firmicutes,24F84@186801|Clostridia,3WKYE@541000|Ruminococcaceae	186801|Clostridia	KT	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_00685	428125.CLOLEP_01246	8.35e-220	634.0	COG0366@1|root,COG0366@2|Bacteria,1TNZ0@1239|Firmicutes,247YM@186801|Clostridia,3WGCV@541000|Ruminococcaceae	186801|Clostridia	G	Alpha amylase, catalytic domain protein	apu	-	2.4.1.25,3.2.1.133,3.2.1.135,3.2.1.20,3.2.1.54	ko:K00705,ko:K01187,ko:K01208	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R02112,R03122,R05196,R06087,R06088,R11262	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH13,GH31,GH77	-	Alpha-amylase,Alpha-amylase_N,Glyco_hydro_77,Malt_amylase_C
HALNLLBL_00687	1120746.CCNL01000007_gene399	2e-190	562.0	COG0826@1|root,COG0826@2|Bacteria,2NPQH@2323|unclassified Bacteria	2|Bacteria	O	Evidence 5 No homology to any previously reported sequences	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
HALNLLBL_00688	428125.CLOLEP_01236	2.98e-59	187.0	COG0756@1|root,COG0756@2|Bacteria,1V6HX@1239|Firmicutes,24K3X@186801|Clostridia,3WK0P@541000|Ruminococcaceae	186801|Clostridia	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
HALNLLBL_00689	428125.CLOLEP_01234	8.8e-185	520.0	COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,247RG@186801|Clostridia,3WGF8@541000|Ruminococcaceae	186801|Clostridia	D	Cell shape determining protein, MreB Mrl family	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
HALNLLBL_00690	1120746.CCNL01000007_gene404	1.6e-53	181.0	COG1792@1|root,COG1792@2|Bacteria,2NPNX@2323|unclassified Bacteria	2|Bacteria	M	Cell shape-determining protein MreC	mreC	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0030428,GO:0031224,GO:0031226,GO:0042546,GO:0043621,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944,GO:0071963	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
HALNLLBL_00692	1105031.HMPREF1141_1472	1.07e-175	525.0	COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,2480Z@186801|Clostridia,36DW0@31979|Clostridiaceae	186801|Clostridia	M	Penicillin-binding Protein	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
HALNLLBL_00693	1105031.HMPREF1141_1471	1.67e-58	192.0	COG2894@1|root,COG2894@2|Bacteria,1TP6P@1239|Firmicutes,249BB@186801|Clostridia,36DQ4@31979|Clostridiaceae	186801|Clostridia	D	Belongs to the ParA family	minD	-	-	ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
HALNLLBL_00694	428125.CLOLEP_01229	4.36e-85	251.0	COG1803@1|root,COG1803@2|Bacteria,1V3KQ@1239|Firmicutes,24FUQ@186801|Clostridia,3WII3@541000|Ruminococcaceae	186801|Clostridia	G	methylglyoxal synthase	mgsA	-	4.2.3.3	ko:K01734	ko00640,ko01120,map00640,map01120	-	R01016	RC00424	ko00000,ko00001,ko01000	-	-	-	MGS
HALNLLBL_00695	1105031.HMPREF1141_1469	3.44e-200	567.0	COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,24852@186801|Clostridia,36FA9@31979|Clostridiaceae	186801|Clostridia	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
HALNLLBL_00696	1514668.JOOA01000002_gene3012	0.0	895.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,247Z3@186801|Clostridia,3WGX1@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
HALNLLBL_00697	1408323.JQKK01000025_gene1380	3.97e-45	159.0	2EN4B@1|root,33FSE@2|Bacteria,1VPF9@1239|Firmicutes,24SXK@186801|Clostridia,27NCJ@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Tim44,zinc_ribbon_2
HALNLLBL_00698	397290.C810_03926	7.57e-146	429.0	COG4260@1|root,COG4260@2|Bacteria,1TRYU@1239|Firmicutes,24901@186801|Clostridia,27ICK@186928|unclassified Lachnospiraceae	186801|Clostridia	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1
HALNLLBL_00699	1201292.DR75_1226	3.02e-98	303.0	COG1645@1|root,COG1645@2|Bacteria,1TRYG@1239|Firmicutes,4ISY0@91061|Bacilli,4B06G@81852|Enterococcaceae	91061|Bacilli	S	bacterial-type flagellum-dependent swarming motility	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_00701	411489.CLOL250_01571	2.08e-149	431.0	COG0502@1|root,COG0502@2|Bacteria,1TPYQ@1239|Firmicutes,248H8@186801|Clostridia,36DIQ@31979|Clostridiaceae	186801|Clostridia	C	radical SAM domain protein	hydE	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
HALNLLBL_00702	585394.RHOM_04680	2.34e-273	756.0	COG0502@1|root,COG0502@2|Bacteria,1TPEX@1239|Firmicutes,248PF@186801|Clostridia	186801|Clostridia	C	biosynthesis protein ThiH	hydG	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
HALNLLBL_00703	877411.JMMA01000002_gene1715	3.77e-176	503.0	COG1160@1|root,COG1160@2|Bacteria,1UI84@1239|Firmicutes,25EDI@186801|Clostridia,3WSKW@541000|Ruminococcaceae	186801|Clostridia	S	Ferrous iron transport protein B	hydF	-	-	-	-	-	-	-	-	-	-	-	MMR_HSR1
HALNLLBL_00704	1121344.JHZO01000005_gene259	3.65e-224	637.0	COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,25AZ5@186801|Clostridia,3WH41@541000|Ruminococcaceae	186801|Clostridia	I	AMP-dependent synthetase and ligase	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C,Cupin_2,HTH_3
HALNLLBL_00705	585394.RHOM_02225	6.87e-124	367.0	COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,248CR@186801|Clostridia	186801|Clostridia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
HALNLLBL_00706	397288.C806_02959	2.82e-147	434.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,25100@186801|Clostridia,27K9X@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HALNLLBL_00707	411902.CLOBOL_04492	1.32e-216	614.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,24946@186801|Clostridia,21XU4@1506553|Lachnoclostridium	186801|Clostridia	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
HALNLLBL_00708	1298920.KI911353_gene4141	6.03e-91	271.0	COG0512@1|root,COG0512@2|Bacteria,1TT9R@1239|Firmicutes,24FR0@186801|Clostridia,21YT9@1506553|Lachnoclostridium	186801|Clostridia	EH	Peptidase C26	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
HALNLLBL_00709	913865.DOT_2164	1.95e-142	413.0	COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,247WY@186801|Clostridia,2600U@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
HALNLLBL_00710	1120933.ATUY01000007_gene575	4.81e-112	330.0	COG0134@1|root,COG0134@2|Bacteria,2GIVV@201174|Actinobacteria,4D348@85005|Actinomycetales	201174|Actinobacteria	E	Indole-3-glycerol phosphate synthase	trpC	GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004425,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043167,GO:0043169,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046391,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
HALNLLBL_00711	509191.AEDB02000098_gene3535	5.54e-241	667.0	COG0133@1|root,COG0133@2|Bacteria,1TPI3@1239|Firmicutes,24881@186801|Clostridia,3WGIV@541000|Ruminococcaceae	186801|Clostridia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
HALNLLBL_00712	1298920.KI911353_gene4146	1.27e-126	366.0	COG0159@1|root,COG0159@2|Bacteria,1TPXA@1239|Firmicutes,248M2@186801|Clostridia,21ZDY@1506553|Lachnoclostridium	186801|Clostridia	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
HALNLLBL_00713	1160721.RBI_I01463	2.6e-131	377.0	COG0846@1|root,COG0846@2|Bacteria,1TQKD@1239|Firmicutes,2491J@186801|Clostridia,3WGSY@541000|Ruminococcaceae	186801|Clostridia	K	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
HALNLLBL_00714	1105031.HMPREF1141_0671	4.73e-27	101.0	COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,24QNX@186801|Clostridia,36KIE@31979|Clostridiaceae	186801|Clostridia	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
HALNLLBL_00716	445973.CLOBAR_00924	1.65e-17	77.4	2E7YJ@1|root,33A8K@2|Bacteria,1VQP8@1239|Firmicutes,24QA7@186801|Clostridia,25U19@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_00717	1415774.U728_2869	4.36e-48	173.0	COG0727@1|root,COG0727@2|Bacteria,1TSB6@1239|Firmicutes,24AQ9@186801|Clostridia,36EKJ@31979|Clostridiaceae	186801|Clostridia	S	N-methylation of lysine residues in flagellin K00599	-	-	-	ko:K18475	-	-	-	-	ko00000,ko01000,ko02035	-	-	-	CxxCxxCC
HALNLLBL_00718	1280692.AUJL01000001_gene118	2.11e-143	428.0	COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,24P7E@186801|Clostridia,36UII@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
HALNLLBL_00719	428125.CLOLEP_00265	1.27e-125	363.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,2484X@186801|Clostridia,3WGIQ@541000|Ruminococcaceae	186801|Clostridia	K	response regulator receiver	-	-	-	ko:K07775	ko02020,map02020	M00458	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HALNLLBL_00720	428125.CLOLEP_00267	3.54e-144	413.0	COG1951@1|root,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,248T7@186801|Clostridia,3WH30@541000|Ruminococcaceae	186801|Clostridia	C	Hydrolyase, tartrate alpha subunit fumarate domain protein, Fe-S type	-	-	4.2.1.2	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
HALNLLBL_00721	428125.CLOLEP_00268	1.38e-95	282.0	COG1838@1|root,COG1838@2|Bacteria,1V1CP@1239|Firmicutes,24FRK@186801|Clostridia,3WI2S@541000|Ruminococcaceae	186801|Clostridia	C	Hydrolyase, tartrate beta subunit fumarate domain protein, Fe-S type	fumB	-	4.2.1.2	ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
HALNLLBL_00722	411462.DORLON_01741	1.65e-44	150.0	COG2246@1|root,COG2246@2|Bacteria,1V7CF@1239|Firmicutes,24KKV@186801|Clostridia,27WTT@189330|Dorea	186801|Clostridia	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
HALNLLBL_00723	511680.BUTYVIB_01614	5.22e-130	380.0	COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,248Q5@186801|Clostridia,4BXYN@830|Butyrivibrio	186801|Clostridia	M	Glycosyltransferase like family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
HALNLLBL_00724	411473.RUMCAL_00956	1.05e-167	518.0	COG4485@1|root,COG4485@2|Bacteria,1TRR1@1239|Firmicutes,24BHM@186801|Clostridia,3WHJ5@541000|Ruminococcaceae	186801|Clostridia	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	GtrA,YfhO
HALNLLBL_00725	1007096.BAGW01000011_gene2296	1.89e-47	155.0	2ANER@1|root,315MJ@2|Bacteria,1V6SU@1239|Firmicutes,24JBZ@186801|Clostridia,2N7GP@216572|Oscillospiraceae	186801|Clostridia	S	SpoVAC/SpoVAEB sporulation membrane protein	spoVAE	-	-	ko:K06407	-	-	-	-	ko00000	-	-	-	SpoVAC_SpoVAEB
HALNLLBL_00726	428125.CLOLEP_02434	1.09e-125	370.0	COG1131@1|root,COG1131@2|Bacteria,1TQUS@1239|Firmicutes,25AZ1@186801|Clostridia,3WH5S@541000|Ruminococcaceae	186801|Clostridia	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HALNLLBL_00727	877411.JMMA01000002_gene271	2e-61	199.0	COG1277@1|root,COG1277@2|Bacteria,1V8QD@1239|Firmicutes,25DA1@186801|Clostridia,3WSGA@541000|Ruminococcaceae	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
HALNLLBL_00728	428125.CLOLEP_02436	3.3e-92	298.0	COG3225@1|root,COG3225@2|Bacteria,1V597@1239|Firmicutes,25DA0@186801|Clostridia,3WSG9@541000|Ruminococcaceae	186801|Clostridia	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
HALNLLBL_00730	397291.C804_02485	5.2e-50	171.0	COG3279@1|root,COG3279@2|Bacteria,1UYV2@1239|Firmicutes,24F5U@186801|Clostridia,27M4M@186928|unclassified Lachnospiraceae	186801|Clostridia	K	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
HALNLLBL_00731	411469.EUBHAL_03061	5.12e-117	339.0	COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,248FV@186801|Clostridia,25V9I@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
HALNLLBL_00733	1384066.JAGT01000001_gene1715	7.93e-25	94.7	COG1396@1|root,COG1396@2|Bacteria,1VM7U@1239|Firmicutes,24UJF@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,HTH_31
HALNLLBL_00734	411463.EUBVEN_01765	2.09e-176	510.0	COG2233@1|root,COG2233@2|Bacteria,1TQKX@1239|Firmicutes,2485Z@186801|Clostridia,25VSJ@186806|Eubacteriaceae	186801|Clostridia	F	Psort location CytoplasmicMembrane, score 10.00	uraA	-	-	ko:K02824	-	-	-	-	ko00000,ko02000	2.A.40.1.1,2.A.40.1.2	-	-	Xan_ur_permease
HALNLLBL_00735	428125.CLOLEP_00230	5.11e-249	701.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,2480U@186801|Clostridia,3WHFZ@541000|Ruminococcaceae	186801|Clostridia	H	acetolactate synthase large subunit	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
HALNLLBL_00736	1410631.JHWZ01000014_gene815	4.38e-47	171.0	COG0775@1|root,COG2843@1|root,COG0775@2|Bacteria,COG2843@2|Bacteria,1U7WK@1239|Firmicutes,247U5@186801|Clostridia,27MD3@186928|unclassified Lachnospiraceae	186801|Clostridia	F	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	mtnN	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
HALNLLBL_00737	428125.CLOLEP_00114	1.89e-71	225.0	COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,249VK@186801|Clostridia,3WIFN@541000|Ruminococcaceae	186801|Clostridia	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
HALNLLBL_00738	428125.CLOLEP_00112	1.88e-44	159.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,249WC@186801|Clostridia,3WGRD@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
HALNLLBL_00739	428125.CLOLEP_00110	2.03e-232	654.0	COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia,3WGN6@541000|Ruminococcaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
HALNLLBL_00740	1499683.CCFF01000016_gene781	0.0	937.0	COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,248E1@186801|Clostridia,36E5W@31979|Clostridiaceae	186801|Clostridia	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
HALNLLBL_00741	1105031.HMPREF1141_2200	2.35e-62	196.0	COG1799@1|root,COG1799@2|Bacteria,1VER3@1239|Firmicutes,24I9Y@186801|Clostridia,36I3V@31979|Clostridiaceae	186801|Clostridia	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	-	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
HALNLLBL_00742	1105031.HMPREF1141_2201	1.32e-62	203.0	COG2302@1|root,COG2302@2|Bacteria,1U5V2@1239|Firmicutes,24GDV@186801|Clostridia,36IWC@31979|Clostridiaceae	186801|Clostridia	S	S4 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	S4
HALNLLBL_00743	411471.SUBVAR_05058	6.57e-20	93.6	COG3599@1|root,COG3599@2|Bacteria,1VGCY@1239|Firmicutes,24TVY@186801|Clostridia,3WM0J@541000|Ruminococcaceae	186801|Clostridia	D	DivIVA domain protein	-	-	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
HALNLLBL_00744	428125.CLOLEP_01959	0.0	1391.0	COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,247XX@186801|Clostridia,3WG9B@541000|Ruminococcaceae	186801|Clostridia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
HALNLLBL_00745	428125.CLOLEP_01960	3.69e-54	175.0	COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,24QPP@186801|Clostridia,3WKYD@541000|Ruminococcaceae	186801|Clostridia	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
HALNLLBL_00746	1384066.JAGT01000001_gene2385	4.23e-142	409.0	COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,247Y2@186801|Clostridia,3WGKV@541000|Ruminococcaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
HALNLLBL_00747	428125.CLOLEP_02366	1.41e-59	185.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,24J83@186801|Clostridia,3WJ8U@541000|Ruminococcaceae	186801|Clostridia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
HALNLLBL_00748	428125.CLOLEP_02367	5.78e-56	183.0	COG0681@1|root,COG0681@2|Bacteria,1V6R3@1239|Firmicutes,25CN6@186801|Clostridia,3WKCK@541000|Ruminococcaceae	186801|Clostridia	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
HALNLLBL_00749	428125.CLOLEP_02367	6.46e-52	172.0	COG0681@1|root,COG0681@2|Bacteria,1V6R3@1239|Firmicutes,25CN6@186801|Clostridia,3WKCK@541000|Ruminococcaceae	186801|Clostridia	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
HALNLLBL_00750	428125.CLOLEP_02368	1.9e-142	409.0	COG1161@1|root,COG1161@2|Bacteria,1TQGK@1239|Firmicutes,2490H@186801|Clostridia,3WGB7@541000|Ruminococcaceae	186801|Clostridia	S	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity	ylqF	-	-	ko:K14540	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1
HALNLLBL_00751	428125.CLOLEP_02369	1.98e-93	282.0	COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,248IT@186801|Clostridia,3WIMJ@541000|Ruminococcaceae	186801|Clostridia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
HALNLLBL_00752	938293.CAJU020000013_gene1508	3.23e-27	103.0	COG0792@1|root,COG0792@2|Bacteria,1VFHQ@1239|Firmicutes,24QNK@186801|Clostridia,22HTU@1570339|Peptoniphilaceae	186801|Clostridia	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
HALNLLBL_00753	642492.Clole_0627	5.08e-68	221.0	COG2355@1|root,COG2355@2|Bacteria,1UA7M@1239|Firmicutes,24AE6@186801|Clostridia	186801|Clostridia	E	PFAM Peptidase M19, renal dipeptidase	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
HALNLLBL_00754	428125.CLOLEP_02372	1.75e-228	644.0	COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,248YY@186801|Clostridia,3WGWF@541000|Ruminococcaceae	186801|Clostridia	E	Threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS16355	PALP,Thr_synth_N
HALNLLBL_00755	1121334.KB911066_gene583	8.69e-102	301.0	COG1768@1|root,COG1768@2|Bacteria,1V3XB@1239|Firmicutes,249BN@186801|Clostridia,3WIIA@541000|Ruminococcaceae	186801|Clostridia	S	Ser Thr phosphatase family protein	-	-	-	ko:K07099	-	-	-	-	ko00000	-	-	-	Metallophos
HALNLLBL_00756	428125.CLOLEP_02374	1.87e-154	451.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,3WGS8@541000|Ruminococcaceae	186801|Clostridia	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
HALNLLBL_00757	428125.CLOLEP_02375	1.53e-107	313.0	COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,247QY@186801|Clostridia,3WGQP@541000|Ruminococcaceae	186801|Clostridia	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
HALNLLBL_00758	428125.CLOLEP_02376	9.46e-203	574.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,2481T@186801|Clostridia,3WGYG@541000|Ruminococcaceae	186801|Clostridia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
HALNLLBL_00759	1120746.CCNL01000011_gene1732	1.8e-299	849.0	COG0466@1|root,COG0466@2|Bacteria,2NNNN@2323|unclassified Bacteria	2|Bacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004175,GO:0004176,GO:0004252,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009314,GO:0009408,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0017171,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051603,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
HALNLLBL_00760	1105031.HMPREF1141_3075	2.11e-80	244.0	COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,24836@186801|Clostridia,36EDR@31979|Clostridiaceae	186801|Clostridia	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
HALNLLBL_00761	1105031.HMPREF1141_3074	2.29e-212	598.0	COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,247X7@186801|Clostridia,36FIT@31979|Clostridiaceae	186801|Clostridia	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS18870	Orn_Arg_deC_N,Orn_DAP_Arg_deC
HALNLLBL_00762	1280698.AUJS01000005_gene2807	2.39e-109	320.0	COG3619@1|root,COG3619@2|Bacteria,1V1VQ@1239|Firmicutes,24DUE@186801|Clostridia,27VY4@189330|Dorea	186801|Clostridia	S	Protein of unknown function (DUF1275)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1275
HALNLLBL_00763	537013.CLOSTMETH_00988	2.04e-14	68.9	COG1396@1|root,COG1396@2|Bacteria,1VK84@1239|Firmicutes,252JX@186801|Clostridia,3WKI0@541000|Ruminococcaceae	186801|Clostridia	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HALNLLBL_00764	411461.DORFOR_00781	1.16e-255	708.0	COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,27V70@189330|Dorea	186801|Clostridia	C	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	gdhA	-	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
HALNLLBL_00765	1120746.CCNL01000011_gene1743	7.9e-138	400.0	COG4974@1|root,COG4974@2|Bacteria,2NP4H@2323|unclassified Bacteria	2|Bacteria	L	Phage integrase, N-terminal SAM-like domain	xerC	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
HALNLLBL_00766	1105031.HMPREF1141_3059	4.28e-35	131.0	28NR9@1|root,2ZBQJ@2|Bacteria,1UZEN@1239|Firmicutes,24G0V@186801|Clostridia,36I0Y@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_00767	1120746.CCNL01000011_gene1739	2.87e-227	637.0	COG1066@1|root,COG1066@2|Bacteria,2NNQG@2323|unclassified Bacteria	2|Bacteria	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
HALNLLBL_00768	428125.CLOLEP_03110	5.13e-62	201.0	COG0860@1|root,COG0860@2|Bacteria,1TQ74@1239|Firmicutes,24FT2@186801|Clostridia,3WIGM@541000|Ruminococcaceae	186801|Clostridia	M	N-acetylmuramoyl-L-alanine amidase	cwlD	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
HALNLLBL_00769	1203606.HMPREF1526_02111	2.63e-161	457.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia,36DNY@31979|Clostridiaceae	186801|Clostridia	E	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24,SEC-C
HALNLLBL_00770	411474.COPEUT_02205	9.87e-308	843.0	COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,247RF@186801|Clostridia	186801|Clostridia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF_1	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7,Pribosyltran
HALNLLBL_00771	138119.DSY3851	0.0	951.0	COG1129@1|root,COG4720@1|root,COG1129@2|Bacteria,COG4720@2|Bacteria,1TQRP@1239|Firmicutes,24YCF@186801|Clostridia,267B9@186807|Peptococcaceae	186801|Clostridia	G	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran,ECF-ribofla_trS,ECF_trnsprt
HALNLLBL_00772	138119.DSY3852	4.73e-107	320.0	COG0619@1|root,COG0619@2|Bacteria,1TSB5@1239|Firmicutes,24AN7@186801|Clostridia,2616E@186807|Peptococcaceae	186801|Clostridia	P	PFAM Cobalt transport protein	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
HALNLLBL_00773	1297617.JPJD01000029_gene2334	1.41e-78	248.0	COG1657@1|root,COG1657@2|Bacteria,1VBUR@1239|Firmicutes,24F29@186801|Clostridia,269AC@186813|unclassified Clostridiales	186801|Clostridia	I	Domain of unknown function (DUF4430)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4430
HALNLLBL_00774	411474.COPEUT_00855	6.3e-102	344.0	COG1657@1|root,COG3209@1|root,COG4733@1|root,COG1657@2|Bacteria,COG3209@2|Bacteria,COG4733@2|Bacteria,1UZVS@1239|Firmicutes,24DV2@186801|Clostridia	186801|Clostridia	I	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF4430,Prenyltrans,SLH,SQHop_cyclase_C
HALNLLBL_00775	1232446.BAIE02000048_gene178	8.98e-13	64.7	COG1918@1|root,COG1918@2|Bacteria,1VK8Z@1239|Firmicutes	1239|Firmicutes	P	Fe2 transport system protein A	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
HALNLLBL_00776	203119.Cthe_1404	2.14e-223	645.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,24885@186801|Clostridia,3WH9H@541000|Ruminococcaceae	186801|Clostridia	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB2	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
HALNLLBL_00777	997884.HMPREF1068_02632	9.84e-118	345.0	COG1234@1|root,COG1234@2|Bacteria,4NH9K@976|Bacteroidetes,2FP6X@200643|Bacteroidia,4AP3W@815|Bacteroidaceae	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
HALNLLBL_00778	411483.FAEPRAA2165_01520	1.24e-278	769.0	COG0641@1|root,COG0641@2|Bacteria,1TQPS@1239|Firmicutes,248DD@186801|Clostridia,3WGAH@541000|Ruminococcaceae	186801|Clostridia	C	Radical SAM	scfB	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
HALNLLBL_00779	657322.FPR_28300	3.53e-15	68.6	2EGRK@1|root,33AHS@2|Bacteria,1VK9R@1239|Firmicutes,24UM0@186801|Clostridia,3WMB3@541000|Ruminococcaceae	186801|Clostridia	S	RSAM-modified six-cysteine peptide	scfA	-	-	-	-	-	-	-	-	-	-	-	SCIFF
HALNLLBL_00780	140626.JHWB01000009_gene1099	1.45e-125	380.0	COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,247RA@186801|Clostridia	186801|Clostridia	E	Orn Lys Arg decarboxylase major	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C
HALNLLBL_00781	1105031.HMPREF1141_1128	2.05e-294	813.0	COG4108@1|root,COG4108@2|Bacteria,1TPYT@1239|Firmicutes,247X3@186801|Clostridia,36DUQ@31979|Clostridiaceae	186801|Clostridia	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
HALNLLBL_00782	1105031.HMPREF1141_3229	1.87e-118	354.0	COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,247P8@186801|Clostridia,36DU5@31979|Clostridiaceae	186801|Clostridia	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
HALNLLBL_00785	1121334.KB911073_gene1922	1.17e-28	112.0	2E8BQ@1|root,332QD@2|Bacteria,1VH5U@1239|Firmicutes,24R1P@186801|Clostridia,3WKW8@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_00786	428125.CLOLEP_03843	2.72e-68	209.0	COG3773@1|root,COG3773@2|Bacteria,1V4KW@1239|Firmicutes,24GK5@186801|Clostridia,3WJ6D@541000|Ruminococcaceae	186801|Clostridia	M	cell wall hydrolase	-	-	3.5.1.28	ko:K01449	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Hydrolase_2
HALNLLBL_00789	1384065.JAGS01000001_gene3244	9.82e-154	453.0	COG2865@1|root,COG2865@2|Bacteria,1U8FY@1239|Firmicutes,24B8W@186801|Clostridia,3WJKE@541000|Ruminococcaceae	186801|Clostridia	K	Putative DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4,HTH_24
HALNLLBL_00790	500632.CLONEX_00486	3.64e-308	852.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247PY@186801|Clostridia	186801|Clostridia	V	abc transporter atp-binding protein	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HALNLLBL_00791	411468.CLOSCI_00939	6.18e-262	736.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247VZ@186801|Clostridia,21YU8@1506553|Lachnoclostridium	186801|Clostridia	V	COG COG1132 ABC-type multidrug transport system, ATPase and permease components	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HALNLLBL_00792	999413.HMPREF1094_03665	9.86e-85	256.0	COG1309@1|root,COG1309@2|Bacteria,1TT2J@1239|Firmicutes	1239|Firmicutes	K	Transcriptional regulator, TetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HALNLLBL_00793	1690.BPSG_0058	1.72e-55	177.0	COG0454@1|root,COG0454@2|Bacteria,2I2HV@201174|Actinobacteria,4D1HR@85004|Bifidobacteriales	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
HALNLLBL_00794	428125.CLOLEP_02009	3.01e-38	129.0	COG1396@1|root,COG1396@2|Bacteria,1VJNB@1239|Firmicutes,24TZB@186801|Clostridia	186801|Clostridia	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19
HALNLLBL_00795	428125.CLOLEP_03333	5.3e-71	217.0	COG0698@1|root,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,24JWT@186801|Clostridia,3WJA1@541000|Ruminococcaceae	186801|Clostridia	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
HALNLLBL_00796	428125.CLOLEP_03334	1.7e-74	233.0	COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,24A0P@186801|Clostridia,3WJ9X@541000|Ruminococcaceae	186801|Clostridia	O	Universal bacterial protein YeaZ	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
HALNLLBL_00797	1120746.CCNL01000013_gene1976	9.98e-63	195.0	COG0802@1|root,COG0802@2|Bacteria,2NPU4@2323|unclassified Bacteria	2|Bacteria	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	yjeE	-	2.7.1.221	ko:K06925,ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	TsaE
HALNLLBL_00798	428125.CLOLEP_03336	3.5e-311	858.0	COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia,3WHBU@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
HALNLLBL_00799	428125.CLOLEP_03338	7.1e-117	352.0	COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,247WS@186801|Clostridia,3WJ15@541000|Ruminococcaceae	186801|Clostridia	D	Belongs to the SEDS family	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
HALNLLBL_00800	397290.C810_03794	1.7e-13	80.5	COG4856@1|root,COG4856@2|Bacteria,1UZEV@1239|Firmicutes,25CGI@186801|Clostridia,27U51@186928|unclassified Lachnospiraceae	186801|Clostridia	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
HALNLLBL_00801	428125.CLOLEP_03097	1.63e-80	252.0	COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,249K8@186801|Clostridia,3WGY9@541000|Ruminococcaceae	186801|Clostridia	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
HALNLLBL_00802	428125.CLOLEP_03096	9.23e-135	397.0	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,249CS@186801|Clostridia,3WH06@541000|Ruminococcaceae	186801|Clostridia	E	cysteine desulfurase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
HALNLLBL_00804	428125.CLOLEP_03141	5.68e-107	316.0	COG0289@1|root,COG0289@2|Bacteria,1TR9D@1239|Firmicutes,248FY@186801|Clostridia,3WH3Y@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS17035	DapB_C,DapB_N
HALNLLBL_00805	428125.CLOLEP_03140	1.3e-130	380.0	COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,247T5@186801|Clostridia,3WGWA@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
HALNLLBL_00806	428125.CLOLEP_03139	4.52e-204	571.0	COG0136@1|root,COG0136@2|Bacteria,1TPC6@1239|Firmicutes,248ZR@186801|Clostridia,3WGVU@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the aspartate-semialdehyde dehydrogenase family	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
HALNLLBL_00807	1514668.JOOA01000002_gene3495	2.93e-179	506.0	COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,247NT@186801|Clostridia,3WGMR@541000|Ruminococcaceae	186801|Clostridia	H	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
HALNLLBL_00808	1120746.CCNL01000011_gene1750	1.17e-214	599.0	COG0343@1|root,COG0343@2|Bacteria,2NNQS@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
HALNLLBL_00809	1120746.CCNL01000011_gene1749	2.23e-21	89.4	COG1862@1|root,COG1862@2|Bacteria	2|Bacteria	U	protein transport	yajC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
HALNLLBL_00811	553973.CLOHYLEM_07441	3.34e-15	83.2	COG1033@1|root,COG1033@2|Bacteria,1VHSF@1239|Firmicutes,24R7H@186801|Clostridia,2217G@1506553|Lachnoclostridium	186801|Clostridia	P	YARHG	-	-	-	-	-	-	-	-	-	-	-	-	YARHG,zinc_ribbon_2
HALNLLBL_00813	428125.CLOLEP_02664	2.98e-75	239.0	COG0564@1|root,COG0564@2|Bacteria,1TS1T@1239|Firmicutes,249AH@186801|Clostridia,3WI75@541000|Ruminococcaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD_2	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
HALNLLBL_00814	663278.Ethha_1081	6.57e-19	81.3	COG3326@1|root,COG3326@2|Bacteria	2|Bacteria	L	Membrane	ysdA	-	-	-	-	-	-	-	-	-	-	-	CSD,DUF1294
HALNLLBL_00815	1120746.CCNL01000012_gene1927	2.33e-108	332.0	COG1649@1|root,COG1649@2|Bacteria,2NP67@2323|unclassified Bacteria	2|Bacteria	S	Glycosyl hydrolase-like 10	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,GHL10
HALNLLBL_00816	428125.CLOLEP_02630	4.11e-166	480.0	COG0621@1|root,COG0621@2|Bacteria,1TPBR@1239|Firmicutes,247IX@186801|Clostridia,3WG80@541000|Ruminococcaceae	186801|Clostridia	J	tRNA methylthiotransferase YqeV	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
HALNLLBL_00818	428125.CLOLEP_02974	1.54e-54	172.0	COG0140@1|root,COG0140@2|Bacteria,1VB6S@1239|Firmicutes,24MP1@186801|Clostridia,3WJ8Q@541000|Ruminococcaceae	186801|Clostridia	E	Phosphoribosyl-ATP	hisE	-	3.6.1.31	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-PH
HALNLLBL_00819	1232443.BAIA02000077_gene312	1.36e-60	187.0	COG0139@1|root,COG0139@2|Bacteria,1UYNA@1239|Firmicutes,247RS@186801|Clostridia	186801|Clostridia	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS05760	His_biosynth,PRA-CH,PRA-PH
HALNLLBL_00820	1120998.AUFC01000003_gene1454	8.67e-97	289.0	COG0106@1|root,COG0106@2|Bacteria,1V1IR@1239|Firmicutes,24GBJ@186801|Clostridia,3WDDN@538999|Clostridiales incertae sedis	186801|Clostridia	E	Histidine biosynthesis protein	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
HALNLLBL_00821	428125.CLOLEP_02972	9.27e-88	263.0	COG0131@1|root,COG0131@2|Bacteria,1TRH7@1239|Firmicutes,247WC@186801|Clostridia,3WH5P@541000|Ruminococcaceae	186801|Clostridia	E	Imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
HALNLLBL_00822	428125.CLOLEP_02971	4.77e-123	366.0	COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,24837@186801|Clostridia,3WGEN@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
HALNLLBL_00823	428125.CLOLEP_02970	6.18e-213	599.0	COG0141@1|root,COG0141@2|Bacteria,1TPAW@1239|Firmicutes,248X8@186801|Clostridia,3WGCJ@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
HALNLLBL_00824	1120746.CCNL01000011_gene1779	2.56e-108	316.0	COG0040@1|root,COG0040@2|Bacteria,2NPCD@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
HALNLLBL_00825	428125.CLOLEP_02968	4.3e-135	399.0	COG3705@1|root,COG3705@2|Bacteria,1TPZZ@1239|Firmicutes,248CB@186801|Clostridia,3WGQF@541000|Ruminococcaceae	186801|Clostridia	E	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
HALNLLBL_00826	1280689.AUJC01000010_gene1811	1.08e-72	239.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,248FS@186801|Clostridia,36EE4@31979|Clostridiaceae	186801|Clostridia	S	hmm pf01594	yhhT	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
HALNLLBL_00827	428125.CLOLEP_02966	0.0	1854.0	COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,248YB@186801|Clostridia,3WGJN@541000|Ruminococcaceae	186801|Clostridia	L	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity	polC	-	2.7.7.7	ko:K02342,ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
HALNLLBL_00828	428125.CLOLEP_02965	8.45e-185	521.0	COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,247N1@186801|Clostridia,3WGBA@541000|Ruminococcaceae	186801|Clostridia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06430	GcpE
HALNLLBL_00829	428125.CLOLEP_02964	3.68e-110	337.0	COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,247MT@186801|Clostridia,3WGQW@541000|Ruminococcaceae	186801|Clostridia	M	Metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
HALNLLBL_00830	1120746.CCNL01000011_gene1784	1.12e-168	483.0	COG0743@1|root,COG0743@2|Bacteria,2NNW2@2323|unclassified Bacteria	2|Bacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0050897,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_1814,iECOK1_1307.ECOK1_0174,iECS88_1305.ECS88_0183,iHN637.CLJU_RS06420,iNJ661.Rv2870c,iUMN146_1321.UM146_23670,iUTI89_1310.UTI89_C0188	DXPR_C,DXP_redisom_C,DXP_reductoisom
HALNLLBL_00831	428125.CLOLEP_02962	4.36e-48	168.0	COG0575@1|root,COG0575@2|Bacteria,1UPNB@1239|Firmicutes,248BP@186801|Clostridia,3WH2Z@541000|Ruminococcaceae	186801|Clostridia	I	Psort location CytoplasmicMembrane, score 10.00	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
HALNLLBL_00832	428125.CLOLEP_02961	9.95e-113	330.0	COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,247TE@186801|Clostridia,3WGF5@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
HALNLLBL_00833	428125.CLOLEP_02960	1.19e-77	236.0	COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,24HWS@186801|Clostridia,3WIRX@541000|Ruminococcaceae	186801|Clostridia	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
HALNLLBL_00834	1120746.CCNL01000011_gene1788	4.64e-137	391.0	COG0528@1|root,COG0528@2|Bacteria,2NNRY@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS06240	AA_kinase
HALNLLBL_00835	273068.TTE2589	5.97e-09	65.1	COG0644@1|root,COG0644@2|Bacteria,1TR0D@1239|Firmicutes,24BE3@186801|Clostridia,42EPU@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Glucose-inhibited division protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
HALNLLBL_00836	202752.JL53_07200	1.65e-43	157.0	COG2017@1|root,COG2017@2|Bacteria,1U26T@1239|Firmicutes,4HA4J@91061|Bacilli,26IST@186820|Listeriaceae	91061|Bacilli	G	LacX protein	-	-	-	-	-	-	-	-	-	-	-	-	Aldose_epim
HALNLLBL_00837	1304880.JAGB01000004_gene1385	1.04e-63	207.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1V1IV@1239|Firmicutes,249XP@186801|Clostridia	186801|Clostridia	KT	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Response_reg
HALNLLBL_00838	1235797.C816_00043	3.57e-23	112.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,25KUJ@186801|Clostridia,2N82B@216572|Oscillospiraceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,His_kinase
HALNLLBL_00840	935948.KE386495_gene1902	1.26e-50	183.0	COG1653@1|root,COG1653@2|Bacteria,1TRIH@1239|Firmicutes,248X0@186801|Clostridia,42ESM@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
HALNLLBL_00841	658086.HMPREF0994_05592	1.21e-86	269.0	COG1175@1|root,COG1175@2|Bacteria,1TREE@1239|Firmicutes,24B75@186801|Clostridia,27IN1@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
HALNLLBL_00842	1158610.UC3_03466	2.47e-71	228.0	COG0395@1|root,COG0395@2|Bacteria,1TRCP@1239|Firmicutes,4HBKE@91061|Bacilli,4AZJK@81852|Enterococcaceae	91061|Bacilli	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
HALNLLBL_00843	1400520.LFAB_15160	1.14e-09	67.8	COG1609@1|root,COG1609@2|Bacteria,1TP9Q@1239|Firmicutes,4HARD@91061|Bacilli,3F3ZM@33958|Lactobacillaceae	91061|Bacilli	K	Transcriptional regulator	araR	-	-	ko:K02103	-	-	-	-	ko00000,ko03000	-	-	-	GntR,Peripla_BP_3
HALNLLBL_00846	1267600.JFGT01000002_gene806	2.6e-07	60.5	COG1609@1|root,COG1609@2|Bacteria,1MVUR@1224|Proteobacteria,1RR4P@1236|Gammaproteobacteria,3VXYC@53335|Pantoea	1236|Gammaproteobacteria	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
HALNLLBL_00848	697329.Rumal_2992	2.68e-63	224.0	COG3475@1|root,COG3475@2|Bacteria,1VBSV@1239|Firmicutes,24C5H@186801|Clostridia,3WKAI@541000|Ruminococcaceae	186801|Clostridia	M	LicD family	licD	-	-	ko:K07271	-	-	-	-	ko00000,ko01000	-	-	-	LicD
HALNLLBL_00849	877411.JMMA01000002_gene2599	5.31e-65	217.0	COG0451@1|root,COG0451@2|Bacteria,1TS59@1239|Firmicutes,247JP@186801|Clostridia,3WJ79@541000|Ruminococcaceae	186801|Clostridia	GM	epimerase dehydratase	-	-	4.1.1.35,4.2.1.46	ko:K01710,ko:K08678	ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00793	R01384,R06513	RC00402,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
HALNLLBL_00850	1160721.RBI_I00539	3.06e-108	319.0	COG1134@1|root,COG1134@2|Bacteria,1TQKK@1239|Firmicutes,24A5V@186801|Clostridia,3WHVP@541000|Ruminococcaceae	186801|Clostridia	GM	Psort location CytoplasmicMembrane, score	tagH	-	3.6.3.40	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.103,3.A.1.104	-	-	ABC_tran,Wzt_C
HALNLLBL_00851	1160721.RBI_I00538	4.62e-87	268.0	COG1682@1|root,COG1682@2|Bacteria,1TQZF@1239|Firmicutes,248R0@186801|Clostridia,3WKBW@541000|Ruminococcaceae	186801|Clostridia	GM	ABC-2 type transporter	tagG	-	-	ko:K09692	ko02010,map02010	M00251	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.104	-	-	ABC2_membrane
HALNLLBL_00852	1507.HMPREF0262_00681	3.89e-107	327.0	COG0687@1|root,COG0687@2|Bacteria,1TPY1@1239|Firmicutes,2483K@186801|Clostridia,36DK4@31979|Clostridiaceae	186801|Clostridia	P	Spermidine putrescine-binding periplasmic protein	potD	-	-	ko:K11069,ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1,SBP_bac_6,SBP_bac_8
HALNLLBL_00853	1120746.CCNL01000011_gene1906	2.27e-85	263.0	COG1177@1|root,COG1177@2|Bacteria,2NPND@2323|unclassified Bacteria	2|Bacteria	E	Binding-protein-dependent transport system inner membrane component	potC	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1,SBP_bac_8
HALNLLBL_00854	1105031.HMPREF1141_0440	1.15e-87	268.0	COG1176@1|root,COG1176@2|Bacteria,1TQ7Z@1239|Firmicutes,247Y8@186801|Clostridia,36EF3@31979|Clostridiaceae	186801|Clostridia	P	ABC-type spermidine putrescine transport system, permease component I	potB	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
HALNLLBL_00855	537013.CLOSTMETH_03656	4.55e-165	481.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3WGI6@541000|Ruminococcaceae	186801|Clostridia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
HALNLLBL_00856	1216932.CM240_0788	1.63e-87	318.0	COG0366@1|root,COG0860@1|root,COG3664@1|root,COG0366@2|Bacteria,COG0860@2|Bacteria,COG3664@2|Bacteria,1TQSE@1239|Firmicutes,24C4V@186801|Clostridia,36GZS@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Big_2,CBM26,CBM53,CW_binding_1,Y_Y_Y
HALNLLBL_00859	1120746.CCNL01000011_gene1572	7.04e-112	335.0	COG1077@1|root,COG1077@2|Bacteria,2NNVU@2323|unclassified Bacteria	2|Bacteria	D	MreB/Mbl protein	mbl	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
HALNLLBL_00860	1121334.KB911070_gene1357	1.46e-36	135.0	COG1040@1|root,COG1040@2|Bacteria,1VF2G@1239|Firmicutes,24IG6@186801|Clostridia	186801|Clostridia	S	ComF family	comF	-	-	ko:K02242	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	Pribosyltran
HALNLLBL_00861	428125.CLOLEP_01537	5.39e-286	809.0	COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,247R7@186801|Clostridia,3WGP3@541000|Ruminococcaceae	186801|Clostridia	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
HALNLLBL_00862	428125.CLOLEP_00456	4.46e-66	211.0	COG3442@1|root,COG3442@2|Bacteria,1U7I9@1239|Firmicutes,24A80@186801|Clostridia,3WKVW@541000|Ruminococcaceae	186801|Clostridia	S	glutamine amidotransferase	-	-	-	ko:K07009	-	-	-	-	ko00000	-	-	-	GATase_3
HALNLLBL_00863	428125.CLOLEP_00455	1.33e-194	553.0	COG0769@1|root,COG0769@2|Bacteria,1UHY9@1239|Firmicutes,25E6X@186801|Clostridia,3WHF5@541000|Ruminococcaceae	186801|Clostridia	M	Domain of unknown function (DUF1727)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1727,Mur_ligase_M
HALNLLBL_00867	428125.CLOLEP_01534	3.16e-27	103.0	2CARW@1|root,33CNX@2|Bacteria,1W1RF@1239|Firmicutes,24X6E@186801|Clostridia,3WQR2@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_00868	428125.CLOLEP_02547	7.58e-21	83.6	2C3DI@1|root,33B22@2|Bacteria,1VK4D@1239|Firmicutes,258DN@186801|Clostridia,3WMHB@541000|Ruminococcaceae	186801|Clostridia	S	Domain of Unknown Function (DUF1540)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1540
HALNLLBL_00869	1232446.BAIE02000072_gene3459	1.09e-15	84.0	COG0679@1|root,COG0679@2|Bacteria,1UY4N@1239|Firmicutes,24ACC@186801|Clostridia,26AFB@186813|unclassified Clostridiales	186801|Clostridia	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
HALNLLBL_00870	1232452.BAIB02000006_gene1264	2.3e-65	205.0	COG0778@1|root,COG0778@2|Bacteria,1V3ZT@1239|Firmicutes,25B9N@186801|Clostridia,26CHC@186813|unclassified Clostridiales	186801|Clostridia	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
HALNLLBL_00871	883156.HMPREF9282_01288	1.25e-86	258.0	COG0778@1|root,COG0778@2|Bacteria,1V4K6@1239|Firmicutes,4H4AS@909932|Negativicutes	909932|Negativicutes	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
HALNLLBL_00872	411461.DORFOR_01751	3.97e-146	419.0	COG0583@1|root,COG0583@2|Bacteria,1TP3E@1239|Firmicutes,248HI@186801|Clostridia,27WHM@189330|Dorea	186801|Clostridia	K	Psort location Cytoplasmic, score 9.98	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
HALNLLBL_00873	1160721.RBI_I01026	6.94e-202	566.0	COG0620@1|root,COG0620@2|Bacteria,1TPDQ@1239|Firmicutes,248U0@186801|Clostridia,3WH02@541000|Ruminococcaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Meth_synt_2
HALNLLBL_00874	1408321.JNJD01000009_gene1864	4.35e-68	221.0	COG0842@1|root,COG0842@2|Bacteria,1TSH0@1239|Firmicutes,24BEN@186801|Clostridia,27MHV@186928|unclassified Lachnospiraceae	186801|Clostridia	V	ABC-2 type transporter	-	-	-	ko:K01992,ko:K11051	ko02010,map02010	M00254,M00298	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.130	-	-	ABC2_membrane,ABC2_membrane_3
HALNLLBL_00875	1278311.AUAL01000016_gene1380	1.21e-112	335.0	COG1131@1|root,COG1131@2|Bacteria,3WTDR@544448|Tenericutes	544448|Tenericutes	V	abc transporter atp-binding protein	-	-	-	ko:K11050	ko02010,map02010	M00298	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.130	-	-	ABC_tran
HALNLLBL_00877	1117108.PAALTS15_01857	2.87e-48	159.0	COG3279@1|root,COG3279@2|Bacteria,1VD10@1239|Firmicutes,4HMF3@91061|Bacilli,274DW@186822|Paenibacillaceae	91061|Bacilli	K	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR
HALNLLBL_00879	411467.BACCAP_01651	2.66e-24	117.0	COG1305@1|root,COG1305@2|Bacteria,1TP8K@1239|Firmicutes,24CZV@186801|Clostridia,268P0@186813|unclassified Clostridiales	186801|Clostridia	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129,Transglut_core
HALNLLBL_00880	742738.HMPREF9460_00437	3.34e-18	91.7	COG1721@1|root,COG1721@2|Bacteria,1UZHY@1239|Firmicutes,24FIT@186801|Clostridia,268QJ@186813|unclassified Clostridiales	186801|Clostridia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
HALNLLBL_00881	641112.ACOK01000097_gene920	9.56e-119	351.0	COG0714@1|root,COG0714@2|Bacteria,1TPKR@1239|Firmicutes,248IM@186801|Clostridia,3WGAD@541000|Ruminococcaceae	186801|Clostridia	S	associated with various cellular activities	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
HALNLLBL_00882	1007096.BAGW01000015_gene1041	7.42e-127	370.0	COG0560@1|root,COG0560@2|Bacteria,1TRRS@1239|Firmicutes,249NX@186801|Clostridia,2N6BI@216572|Oscillospiraceae	186801|Clostridia	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
HALNLLBL_00883	1121334.KB911069_gene1717	1.16e-59	200.0	COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,2504A@186801|Clostridia	186801|Clostridia	O	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	-	-	-	-	-	-	-	-	-	-	Pro_isomerase
HALNLLBL_00884	1120746.CCNL01000013_gene1993	3.06e-105	316.0	COG0539@1|root,COG0539@2|Bacteria	2|Bacteria	J	ribosomal small subunit biogenesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,S1
HALNLLBL_00885	545696.HOLDEFILI_01435	2.06e-133	398.0	COG1322@1|root,COG1322@2|Bacteria,1TPWI@1239|Firmicutes,3VQCE@526524|Erysipelotrichia	526524|Erysipelotrichia	S	RmuC domain protein	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
HALNLLBL_00887	645991.Sgly_2182	5.26e-20	99.0	COG4219@1|root,COG4219@2|Bacteria,1VCEX@1239|Firmicutes,24NT6@186801|Clostridia	186801|Clostridia	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
HALNLLBL_00889	1203606.HMPREF1526_02400	6.29e-101	300.0	COG1738@1|root,COG1738@2|Bacteria,1TSAY@1239|Firmicutes,24EFG@186801|Clostridia,36Q0T@31979|Clostridiaceae	186801|Clostridia	S	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
HALNLLBL_00890	1029718.SFBM_1150	9.6e-114	332.0	COG1244@1|root,COG1244@2|Bacteria,1UZ5M@1239|Firmicutes,24AIM@186801|Clostridia,36G6G@31979|Clostridiaceae	186801|Clostridia	S	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_00891	1160721.RBI_II00028	4.94e-37	131.0	COG1399@1|root,COG1399@2|Bacteria,1VEXU@1239|Firmicutes,24RKT@186801|Clostridia,3WJHF@541000|Ruminococcaceae	186801|Clostridia	S	metal-binding, possibly nucleic acid-binding protein	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
HALNLLBL_00892	428125.CLOLEP_00453	2.48e-20	82.4	COG0333@1|root,COG0333@2|Bacteria,1VEFI@1239|Firmicutes,24QM0@186801|Clostridia,3WKID@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
HALNLLBL_00893	428125.CLOLEP_00452	2.26e-171	494.0	COG1625@1|root,COG1625@2|Bacteria,1TSFU@1239|Firmicutes,247JK@186801|Clostridia,3WGI9@541000|Ruminococcaceae	186801|Clostridia	C	FeS-containing Cyanobacterial-specific oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DUF512
HALNLLBL_00894	428125.CLOLEP_00451	8.13e-231	645.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,2493T@186801|Clostridia,3WGNU@541000|Ruminococcaceae	186801|Clostridia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
HALNLLBL_00895	428125.CLOLEP_00450	1.3e-62	202.0	COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,24JA2@186801|Clostridia,3WJFE@541000|Ruminococcaceae	186801|Clostridia	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
HALNLLBL_00896	428125.CLOLEP_01894	8.87e-49	158.0	COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,24JCW@186801|Clostridia,3WJJW@541000|Ruminococcaceae	186801|Clostridia	FG	Psort location Cytoplasmic, score	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
HALNLLBL_00897	428125.CLOLEP_01895	1.05e-83	252.0	COG0503@1|root,COG0503@2|Bacteria,1V1XS@1239|Firmicutes,25QBJ@186801|Clostridia,3WIP6@541000|Ruminococcaceae	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
HALNLLBL_00899	428125.CLOLEP_01896	2.91e-58	219.0	COG0658@1|root,COG0658@2|Bacteria,1VGSX@1239|Firmicutes,249H4@186801|Clostridia,3WKE7@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence
HALNLLBL_00900	1262449.CP6013_2186	1.47e-21	101.0	COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,24ASN@186801|Clostridia,36FMH@31979|Clostridiaceae	186801|Clostridia	L	DNA polymerase III delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
HALNLLBL_00901	663278.Ethha_2087	1.19e-62	199.0	COG1658@1|root,COG1658@2|Bacteria,1V3K3@1239|Firmicutes,24I8W@186801|Clostridia,3WIWX@541000|Ruminococcaceae	186801|Clostridia	L	Ribonuclease M5	rnmV	-	3.1.26.8	ko:K05985	-	-	-	-	ko00000,ko01000	-	-	-	DUF4093,Toprim,Toprim_4
HALNLLBL_00902	748727.CLJU_c42470	7.88e-06	50.4	COG4905@1|root,COG4905@2|Bacteria,1VA0H@1239|Firmicutes,24NAK@186801|Clostridia,36MWU@31979|Clostridiaceae	186801|Clostridia	S	Putative ABC-transporter type IV	-	-	-	-	-	-	-	-	-	-	-	-	ABC_trans_CmpB
HALNLLBL_00903	428125.CLOLEP_02644	2.54e-125	377.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,3WGDS@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
HALNLLBL_00904	428125.CLOLEP_02951	2.17e-105	314.0	COG0740@1|root,COG0740@2|Bacteria,1TPX2@1239|Firmicutes,249QX@186801|Clostridia,3WGED@541000|Ruminococcaceae	186801|Clostridia	OU	Psort location Cytoplasmic, score	tepA	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
HALNLLBL_00905	1105031.HMPREF1141_2936	8.42e-92	282.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,249KK@186801|Clostridia,36EFN@31979|Clostridiaceae	186801|Clostridia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
HALNLLBL_00906	428125.CLOLEP_02952	6.22e-222	659.0	COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,247KM@186801|Clostridia,3WGRB@541000|Ruminococcaceae	186801|Clostridia	D	Belongs to the FtsK SpoIIIE SftA family	spoIIIE	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
HALNLLBL_00907	428125.CLOLEP_02954	1.46e-312	868.0	COG1032@1|root,COG1032@2|Bacteria,1TQ8X@1239|Firmicutes,248IW@186801|Clostridia,3WGM7@541000|Ruminococcaceae	186801|Clostridia	C	UPF0313 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
HALNLLBL_00908	1262449.CP6013_4051	1.16e-43	156.0	COG2333@1|root,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia,36DFY@31979|Clostridiaceae	186801|Clostridia	L	domain protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Ada_Zn_binding,Lactamase_B
HALNLLBL_00909	411459.RUMOBE_01174	6.1e-231	643.0	COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,247QC@186801|Clostridia,3XYHR@572511|Blautia	186801|Clostridia	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
HALNLLBL_00910	592026.GCWU0000282_002789	1.18e-47	157.0	COG1970@1|root,COG1970@2|Bacteria,1VA14@1239|Firmicutes,24JAB@186801|Clostridia	186801|Clostridia	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
HALNLLBL_00911	1499683.CCFF01000017_gene1801	1.4e-265	747.0	COG0367@1|root,COG0367@2|Bacteria,1TRPB@1239|Firmicutes,247YA@186801|Clostridia,36ERR@31979|Clostridiaceae	186801|Clostridia	E	asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
HALNLLBL_00912	693746.OBV_35770	1.9e-23	106.0	COG3314@1|root,COG3314@2|Bacteria,1TR0V@1239|Firmicutes,247XA@186801|Clostridia,2N6DP@216572|Oscillospiraceae	186801|Clostridia	S	Sporulation integral membrane protein YlbJ	ylbJ	-	-	-	-	-	-	-	-	-	-	-	Gate
HALNLLBL_00914	537013.CLOSTMETH_02605	9.48e-44	164.0	COG1589@1|root,COG1589@2|Bacteria,1UHVF@1239|Firmicutes,25E4A@186801|Clostridia,3WIPX@541000|Ruminococcaceae	186801|Clostridia	M	Putative stage IV sporulation protein YqfD	yqfD	-	-	ko:K06438	-	-	-	-	ko00000	-	-	-	YqfD
HALNLLBL_00915	428125.CLOLEP_03966	1.61e-116	341.0	COG1692@1|root,COG1692@2|Bacteria,1TR9P@1239|Firmicutes,24967@186801|Clostridia,3WHB0@541000|Ruminococcaceae	186801|Clostridia	S	metallophosphoesterase	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
HALNLLBL_00916	428125.CLOLEP_03963	7.46e-231	655.0	COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,247XI@186801|Clostridia,3WH9C@541000|Ruminococcaceae	186801|Clostridia	S	DAK2 domain fusion protein YloV	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
HALNLLBL_00917	428125.CLOLEP_03962	6.53e-246	703.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia,3WG7A@541000|Ruminococcaceae	186801|Clostridia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
HALNLLBL_00918	1105031.HMPREF1141_0730	3.17e-127	383.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,36EWK@31979|Clostridiaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	dacF1	-	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
HALNLLBL_00919	1105031.HMPREF1141_1498	1.58e-76	231.0	COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,24HFT@186801|Clostridia,36HY1@31979|Clostridiaceae	186801|Clostridia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
HALNLLBL_00920	1160721.RBI_II00013	3.02e-65	202.0	2CAVT@1|root,304CC@2|Bacteria,1V4J6@1239|Firmicutes,24HQA@186801|Clostridia,3WK7E@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2798
HALNLLBL_00921	1499685.CCFJ01000046_gene3155	7.49e-15	69.3	2DR1Y@1|root,339TZ@2|Bacteria,1VK7M@1239|Firmicutes,4HR6A@91061|Bacilli,1ZKCJ@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF3006)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3006
HALNLLBL_00922	1121423.JONT01000016_gene1171	6.13e-82	258.0	COG2333@1|root,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia,2617G@186807|Peptococcaceae	186801|Clostridia	S	PFAM Metallo-beta-lactamase superfamily	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Ada_Zn_binding,LTD,Lactamase_B
HALNLLBL_00923	622312.ROSEINA2194_02622	0.0	894.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HALNLLBL_00924	622312.ROSEINA2194_02623	3.24e-264	741.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia	186801|Clostridia	V	Abc transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HALNLLBL_00925	1235799.C818_00669	8.26e-38	134.0	COG1846@1|root,COG1846@2|Bacteria,1VEYN@1239|Firmicutes,24S21@186801|Clostridia,27NN2@186928|unclassified Lachnospiraceae	186801|Clostridia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
HALNLLBL_00927	622312.ROSEINA2194_03846	2.44e-57	194.0	COG1295@1|root,COG1295@2|Bacteria,1U7HM@1239|Firmicutes,24A2Q@186801|Clostridia	186801|Clostridia	H	Belongs to the UPF0761 family	yihY	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
HALNLLBL_00928	537013.CLOSTMETH_00229	2.91e-90	274.0	COG0300@1|root,COG0300@2|Bacteria,1UZHA@1239|Firmicutes,248C8@186801|Clostridia,3WHWH@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
HALNLLBL_00929	903814.ELI_2646	1.47e-59	196.0	COG0500@1|root,COG4224@1|root,COG2226@2|Bacteria,COG4224@2|Bacteria,1V53X@1239|Firmicutes,24IQW@186801|Clostridia,25WQC@186806|Eubacteriaceae	186801|Clostridia	Q	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1653,Methyltransf_11,Methyltransf_25
HALNLLBL_00930	1321782.HMPREF1986_02024	2.27e-22	98.6	2E63V@1|root,330SW@2|Bacteria,1VJ4Y@1239|Firmicutes,24U7K@186801|Clostridia,2PSJN@265975|Oribacterium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_00931	1120746.CCNL01000008_gene479	7.08e-186	533.0	COG2265@1|root,COG2265@2|Bacteria,2NNWX@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
HALNLLBL_00932	428125.CLOLEP_01540	3.66e-224	630.0	COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,2484K@186801|Clostridia,3WGQ1@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HALNLLBL_00934	903814.ELI_0802	2.52e-18	96.7	COG3290@1|root,COG3290@2|Bacteria,1VC62@1239|Firmicutes,25FKE@186801|Clostridia,25ZJW@186806|Eubacteriaceae	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
HALNLLBL_00935	545696.HOLDEFILI_02110	2.04e-17	85.9	COG3279@1|root,COG3279@2|Bacteria,1VC9Q@1239|Firmicutes,3VS40@526524|Erysipelotrichia	526524|Erysipelotrichia	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
HALNLLBL_00936	903814.ELI_2078	1.05e-100	318.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,247M5@186801|Clostridia,25UX6@186806|Eubacteriaceae	186801|Clostridia	O	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
HALNLLBL_00938	203119.Cthe_0507	5.61e-17	85.5	COG5018@1|root,COG5018@2|Bacteria,1TQJZ@1239|Firmicutes,24845@186801|Clostridia,3WM2I@541000|Ruminococcaceae	186801|Clostridia	L	Exonuclease	-	-	-	-	-	-	-	-	-	-	-	-	RNase_T
HALNLLBL_00939	428125.CLOLEP_01573	0.0	994.0	COG1217@1|root,COG1217@2|Bacteria,1TQ5Y@1239|Firmicutes,248EB@186801|Clostridia,3WGEU@541000|Ruminococcaceae	186801|Clostridia	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2
HALNLLBL_00940	1410617.JHXH01000004_gene1288	0.0	1006.0	COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,25HJM@186801|Clostridia,3WG9R@541000|Ruminococcaceae	186801|Clostridia	C	aconitate hydratase	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
HALNLLBL_00941	1160721.RBI_I01385	9.29e-246	680.0	COG0538@1|root,COG0538@2|Bacteria,1TSKB@1239|Firmicutes,247KX@186801|Clostridia,3WGXI@541000|Ruminococcaceae	186801|Clostridia	C	Belongs to the isocitrate and isopropylmalate dehydrogenases family	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
HALNLLBL_00942	1120746.CCNL01000013_gene1988	6.02e-87	262.0	COG2344@1|root,COG2344@2|Bacteria,2NPI1@2323|unclassified Bacteria	2|Bacteria	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
HALNLLBL_00943	1499683.CCFF01000014_gene3594	3.15e-186	563.0	COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,2481P@186801|Clostridia,36E5I@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 13 family	pulA	-	3.2.1.41	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	-	R02111	-	ko00000,ko00001,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
HALNLLBL_00944	1499683.CCFF01000014_gene3594	6.41e-195	582.0	COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,2481P@186801|Clostridia,36E5I@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 13 family	pulA	-	3.2.1.41	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	-	R02111	-	ko00000,ko00001,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
HALNLLBL_00945	1123489.AUAN01000002_gene752	5.24e-183	523.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,4H2GC@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
HALNLLBL_00946	1414720.CBYM010000002_gene655	2.19e-22	96.7	COG1388@1|root,COG3757@1|root,COG1388@2|Bacteria,COG3757@2|Bacteria,1V484@1239|Firmicutes,24A8T@186801|Clostridia,36FZK@31979|Clostridiaceae	186801|Clostridia	M	family 25	lyc2	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.2.1.17	ko:K01185,ko:K07273	-	-	-	-	ko00000,ko01000	-	-	-	CW_binding_1,Glyco_hydro_25,LysM,PG_binding_1,SH3_3
HALNLLBL_00947	742738.HMPREF9460_00778	4.45e-20	86.3	COG3824@1|root,COG3824@2|Bacteria,1VFAZ@1239|Firmicutes,24RK0@186801|Clostridia,2693S@186813|unclassified Clostridiales	186801|Clostridia	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Maf,Zincin_1
HALNLLBL_00948	428125.CLOLEP_03935	1.9e-204	572.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,3WGMV@541000|Ruminococcaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
HALNLLBL_00949	1121334.KB911066_gene1111	5.14e-210	604.0	COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,2480W@186801|Clostridia,3WGFW@541000|Ruminococcaceae	186801|Clostridia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
HALNLLBL_00950	1120746.CCNL01000011_gene1555	3.75e-79	242.0	COG1739@1|root,COG1739@2|Bacteria,2NPZP@2323|unclassified Bacteria	2|Bacteria	S	Uncharacterized protein family UPF0029	yigZ	-	2.1.1.45,3.4.13.9	ko:K00560,ko:K01271	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	DUF1949,UPF0029
HALNLLBL_00951	1235797.C816_00840	6.21e-39	129.0	COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,24QNZ@186801|Clostridia,2N7PC@216572|Oscillospiraceae	186801|Clostridia	J	Ribosomal protein L31	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
HALNLLBL_00952	428125.CLOLEP_03927	3.55e-27	114.0	COG1876@1|root,COG1876@2|Bacteria	2|Bacteria	M	D-alanyl-D-alanine carboxypeptidase	vanY	-	3.4.17.14	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	VanY
HALNLLBL_00953	1160721.RBI_I00437	0.0	1054.0	COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia,3WGVM@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
HALNLLBL_00958	180332.JTGN01000001_gene5260	3.4e-185	531.0	COG0534@1|root,COG0534@2|Bacteria,1TP5P@1239|Firmicutes,247PQ@186801|Clostridia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HALNLLBL_00959	1203606.HMPREF1526_01931	5.16e-19	92.4	COG0860@1|root,COG3023@1|root,COG0860@2|Bacteria,COG3023@2|Bacteria,1TRDG@1239|Firmicutes,24ABM@186801|Clostridia,36M5E@31979|Clostridiaceae	186801|Clostridia	MV	N-acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,CW_7,SH3_5,SPOR
HALNLLBL_00961	1232453.BAIF02000059_gene1610	8.21e-13	64.7	2DRAZ@1|root,33B0U@2|Bacteria,1VN37@1239|Firmicutes,24WNH@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_00962	1120746.CCNL01000011_gene1768	0.0	1467.0	COG0178@1|root,COG0178@2|Bacteria,2NNT3@2323|unclassified Bacteria	2|Bacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
HALNLLBL_00963	1105031.HMPREF1141_0307	8.2e-277	780.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia,36DIC@31979|Clostridiaceae	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
HALNLLBL_00964	1120746.CCNL01000013_gene2022	2.91e-71	220.0	COG0634@1|root,COG0634@2|Bacteria,2NPER@2323|unclassified Bacteria	2|Bacteria	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	GO:0003674,GO:0003824,GO:0004422,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006188,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0052657,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.8,6.3.4.19	ko:K00760,ko:K04075,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245,R09597	RC00063,RC00122,RC02633,RC02634	ko00000,ko00001,ko01000,ko03016	-	-	-	Pribosyltran
HALNLLBL_00965	1514668.JOOA01000002_gene3067	3.63e-73	243.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,248TY@186801|Clostridia,3WHDC@541000|Ruminococcaceae	186801|Clostridia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
HALNLLBL_00966	428125.CLOLEP_02597	1.25e-209	593.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,3WH8B@541000|Ruminococcaceae	186801|Clostridia	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
HALNLLBL_00967	428125.CLOLEP_02596	2.1e-63	197.0	COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,24MT6@186801|Clostridia,3WJCC@541000|Ruminococcaceae	186801|Clostridia	J	binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
HALNLLBL_00968	428125.CLOLEP_02595	1.01e-183	541.0	COG3887@1|root,COG3887@2|Bacteria,1TPGP@1239|Firmicutes,2484R@186801|Clostridia,3WH8C@541000|Ruminococcaceae	186801|Clostridia	T	domain protein	yybT	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
HALNLLBL_00969	428125.CLOLEP_02592	5.37e-301	842.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,2488J@186801|Clostridia,3WH9M@541000|Ruminococcaceae	186801|Clostridia	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
HALNLLBL_00970	1105031.HMPREF1141_0314	4.43e-78	234.0	COG0328@1|root,COG0328@2|Bacteria,1V4A0@1239|Firmicutes,24FSS@186801|Clostridia,36IBC@31979|Clostridiaceae	186801|Clostridia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
HALNLLBL_00971	1120746.CCNL01000013_gene2029	5.94e-207	581.0	COG1104@1|root,COG1104@2|Bacteria,2NNVR@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
HALNLLBL_00972	1120746.CCNL01000013_gene2030	1.26e-87	258.0	COG0822@1|root,COG0822@2|Bacteria,2NPRS@2323|unclassified Bacteria	2|Bacteria	C	NifU-like N terminal domain	nifU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
HALNLLBL_00973	471875.RUMLAC_02055	6.65e-55	173.0	COG1917@1|root,COG1917@2|Bacteria,1V6IB@1239|Firmicutes,24JTU@186801|Clostridia,3WJYH@541000|Ruminococcaceae	186801|Clostridia	S	Cupin domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
HALNLLBL_00974	633697.EubceDRAFT1_1847	2.68e-28	114.0	COG4464@1|root,COG4464@2|Bacteria,1TQ1T@1239|Firmicutes,24JQU@186801|Clostridia,25XCI@186806|Eubacteriaceae	186801|Clostridia	GM	Capsular polysaccharide biosynthesis protein	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	-
HALNLLBL_00975	428125.CLOLEP_02914	7.35e-199	557.0	COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,24A63@186801|Clostridia,3WG9H@541000|Ruminococcaceae	186801|Clostridia	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
HALNLLBL_00976	428125.CLOLEP_02913	8.84e-84	255.0	COG0406@1|root,COG0406@2|Bacteria,1V6G1@1239|Firmicutes,24JP4@186801|Clostridia,3WJCY@541000|Ruminococcaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	cobC	-	3.1.3.73	ko:K02226	ko00860,ko01100,map00860,map01100	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
HALNLLBL_00977	428125.CLOLEP_02912	6.16e-55	182.0	COG1396@1|root,COG1396@2|Bacteria,1V2ZX@1239|Firmicutes,24EC9@186801|Clostridia,3WIEA@541000|Ruminococcaceae	186801|Clostridia	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
HALNLLBL_00978	1120746.CCNL01000011_gene1799	1.98e-57	180.0	COG2337@1|root,COG2337@2|Bacteria,2NS2Z@2323|unclassified Bacteria	2|Bacteria	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	ndoA	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
HALNLLBL_00980	411474.COPEUT_01919	3.04e-70	214.0	2DU3D@1|root,32UWH@2|Bacteria,1V6ZJ@1239|Firmicutes,24PSR@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4829
HALNLLBL_00981	1280681.AUJZ01000016_gene2194	2.07e-96	285.0	COG2206@1|root,COG2206@2|Bacteria,1UZ46@1239|Firmicutes,25FEK@186801|Clostridia,4BYSY@830|Butyrivibrio	186801|Clostridia	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HDOD
HALNLLBL_00982	1120746.CCNL01000011_gene1801	4.51e-71	234.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2NNR2@2323|unclassified Bacteria	2|Bacteria	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
HALNLLBL_00984	1514668.JOOA01000002_gene1723	6.43e-192	539.0	COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,2486E@186801|Clostridia,3WGWV@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
HALNLLBL_00985	1280694.AUJQ01000005_gene1380	0.0	1088.0	COG0072@1|root,COG0072@2|Bacteria,1TP98@1239|Firmicutes,248BJ@186801|Clostridia,3NGHV@46205|Pseudobutyrivibrio	186801|Clostridia	J	B3/4 domain	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
HALNLLBL_00986	641112.ACOK01000101_gene411	5.55e-37	125.0	COG4472@1|root,COG4472@2|Bacteria,1VAC4@1239|Firmicutes,24QVQ@186801|Clostridia,3WJXE@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the UPF0297 family	yrzL	-	-	-	-	-	-	-	-	-	-	-	DUF965
HALNLLBL_00987	1120746.CCNL01000011_gene1810	8.58e-36	124.0	2DG94@1|root,337GI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_00988	1121428.DESHY_10081___1	1.47e-29	107.0	COG3077@1|root,COG3077@2|Bacteria,1V8Q7@1239|Firmicutes,24MBT@186801|Clostridia	186801|Clostridia	L	Addiction module antitoxin, RelB DinJ family	-	-	-	-	-	-	-	-	-	-	-	-	RelB
HALNLLBL_00989	478749.BRYFOR_08890	0.0	1092.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	actP	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
HALNLLBL_00990	411462.DORLON_02320	1.21e-47	154.0	COG1937@1|root,COG1937@2|Bacteria,1VEF5@1239|Firmicutes,24QRR@186801|Clostridia,27VQM@189330|Dorea	186801|Clostridia	S	Metal-sensitive transcriptional repressor	csoR	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
HALNLLBL_00991	411468.CLOSCI_01687	2.15e-18	80.5	COG3077@1|root,COG3077@2|Bacteria,1VABY@1239|Firmicutes,24PQZ@186801|Clostridia,220K7@1506553|Lachnoclostridium	186801|Clostridia	L	RelB antitoxin	-	-	-	ko:K07473	-	-	-	-	ko00000,ko02048	-	-	-	RelB
HALNLLBL_00992	411459.RUMOBE_02609	5.62e-35	121.0	COG3041@1|root,COG3041@2|Bacteria,1VENE@1239|Firmicutes,24MW1@186801|Clostridia,3Y0QQ@572511|Blautia	186801|Clostridia	S	Bacterial toxin of type II toxin-antitoxin system, YafQ	-	-	-	ko:K19157	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	YafQ_toxin
HALNLLBL_00993	537013.CLOSTMETH_00061	2.35e-39	131.0	COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,24MQV@186801|Clostridia,3WJU7@541000|Ruminococcaceae	186801|Clostridia	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
HALNLLBL_00994	1121334.KB911069_gene1617	9.1e-50	164.0	COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,24HF9@186801|Clostridia,3WJAP@541000|Ruminococcaceae	186801|Clostridia	L	Single-stranded DNA-binding protein	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
HALNLLBL_00995	428125.CLOLEP_00519	8.44e-42	139.0	COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,24QZQ@186801|Clostridia,3WK85@541000|Ruminococcaceae	186801|Clostridia	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
HALNLLBL_00996	246199.CUS_7705	3.51e-72	224.0	COG0135@1|root,COG0135@2|Bacteria,1V6Y0@1239|Firmicutes,24HBQ@186801|Clostridia,3WM7Q@541000|Ruminococcaceae	186801|Clostridia	E	N-(5'phosphoribosyl)anthranilate (PRA) isomerase	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
HALNLLBL_00997	1160721.RBI_I00675	1.45e-161	459.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,2497G@186801|Clostridia,3WG9Z@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
HALNLLBL_00998	1160721.RBI_I00452	2.78e-246	684.0	COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,3WGNF@541000|Ruminococcaceae	186801|Clostridia	E	O-acetylhomoserine	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
HALNLLBL_00999	246199.CUS_8114	1.27e-59	187.0	COG1959@1|root,COG1959@2|Bacteria,1V3QB@1239|Firmicutes,24JIV@186801|Clostridia,3WJN5@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
HALNLLBL_01000	665956.HMPREF1032_01860	2.93e-173	501.0	COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,2483Q@186801|Clostridia,3WP2F@541000|Ruminococcaceae	186801|Clostridia	S	Permease family	-	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
HALNLLBL_01001	1120746.CCNL01000010_gene1166	4.96e-99	294.0	COG1191@1|root,COG1191@2|Bacteria,2NR0Y@2323|unclassified Bacteria	2|Bacteria	K	Sigma-70 region 2	sigK	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
HALNLLBL_01003	1120746.CCNL01000011_gene1909	3.28e-60	213.0	COG0791@1|root,COG3409@1|root,COG0791@2|Bacteria,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	ydhO	-	3.4.14.13	ko:K20742,ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60,PG_binding_1,YkuD
HALNLLBL_01004	428125.CLOLEP_03258	6.4e-207	586.0	COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,247X2@186801|Clostridia,3WGT0@541000|Ruminococcaceae	186801|Clostridia	L	ATPase, AAA family	yrvN	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
HALNLLBL_01005	1121935.AQXX01000121_gene5516	2.11e-07	63.2	COG0366@1|root,COG1523@1|root,COG0366@2|Bacteria,COG1523@2|Bacteria,1MU90@1224|Proteobacteria,1RQ1S@1236|Gammaproteobacteria,1XN5H@135619|Oceanospirillales	135619|Oceanospirillales	G	Alpha-amylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
HALNLLBL_01006	1449050.JNLE01000003_gene2028	6.09e-215	637.0	COG0366@1|root,COG3291@1|root,COG0366@2|Bacteria,COG3291@2|Bacteria,1V0U1@1239|Firmicutes,24ZQ4@186801|Clostridia	186801|Clostridia	G	Alpha amylase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
HALNLLBL_01008	1160721.RBI_I00653	2.4e-217	605.0	COG0371@1|root,COG0371@2|Bacteria,1TQFU@1239|Firmicutes,248KH@186801|Clostridia,3WMZC@541000|Ruminococcaceae	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	gldA	-	1.1.1.6	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	-	R01034,R10715,R10717	RC00029,RC00117,RC00670	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
HALNLLBL_01009	1519439.JPJG01000055_gene2199	2.59e-265	744.0	COG1001@1|root,COG1001@2|Bacteria,1TP84@1239|Firmicutes,247KN@186801|Clostridia,2N6Y1@216572|Oscillospiraceae	186801|Clostridia	F	Adenine deaminase C-terminal domain	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
HALNLLBL_01011	140626.JHWB01000022_gene2089	5.07e-31	122.0	28KBJ@1|root,2Z9YJ@2|Bacteria,1V10F@1239|Firmicutes,24WPP@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01014	1235799.C818_01939	9.23e-92	274.0	COG1131@1|root,COG1131@2|Bacteria,1V1P4@1239|Firmicutes,249VI@186801|Clostridia,27K3J@186928|unclassified Lachnospiraceae	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HALNLLBL_01016	428125.CLOLEP_03817	7.54e-33	117.0	2DNEB@1|root,32X30@2|Bacteria,1VE4J@1239|Firmicutes,24NUX@186801|Clostridia,3WMF3@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01018	1235792.C808_01828	1.51e-38	132.0	2C5R4@1|root,2ZC1N@2|Bacteria,1V5QY@1239|Firmicutes,24JU0@186801|Clostridia,27N4Y@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
HALNLLBL_01019	1131462.DCF50_p134	1.06e-58	209.0	COG0419@1|root,COG0419@2|Bacteria	2|Bacteria	L	ATPase involved in DNA repair	-	-	-	ko:K02057,ko:K03546,ko:K07459,ko:K10110	ko02010,map02010	M00194,M00221	-	-	ko00000,ko00001,ko00002,ko02000,ko03400	3.A.1.1.1,3.A.1.1.22,3.A.1.2	-	-	AAA_11,AAA_12,AAA_13,AAA_15,AAA_23,DUF3732
HALNLLBL_01020	1235796.C815_01330	1.43e-134	391.0	COG0270@1|root,COG0270@2|Bacteria,1TS3G@1239|Firmicutes	1239|Firmicutes	H	Methyltransferase	dcm	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
HALNLLBL_01021	445971.ANASTE_00885	1.01e-181	527.0	COG0270@1|root,COG0270@2|Bacteria,1TS3G@1239|Firmicutes,249Q9@186801|Clostridia,25VMQ@186806|Eubacteriaceae	186801|Clostridia	H	Psort location Cytoplasmic, score	dcm	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
HALNLLBL_01022	478749.BRYFOR_09017	8.69e-58	185.0	2CJ2T@1|root,32S93@2|Bacteria,1VDGQ@1239|Firmicutes,24W2G@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01023	388919.SSA_1818	3.14e-63	197.0	COG3727@1|root,COG3727@2|Bacteria,1V3S8@1239|Firmicutes,4HJ0T@91061|Bacilli	91061|Bacilli	L	May nick specific sequences that contain T G mispairs resulting from m5C-deamination	vsr	-	-	ko:K07458	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DUF559,Vsr
HALNLLBL_01026	877414.ATWA01000005_gene696	1.68e-117	359.0	COG3843@1|root,COG3843@2|Bacteria,1TPRX@1239|Firmicutes,248VT@186801|Clostridia,267ZY@186813|unclassified Clostridiales	186801|Clostridia	U	Relaxase/Mobilisation nuclease domain	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
HALNLLBL_01027	1507.HMPREF0262_00054	1.8e-88	273.0	COG1475@1|root,COG1475@2|Bacteria,1TR7C@1239|Firmicutes,247TW@186801|Clostridia,36HAM@31979|Clostridiaceae	186801|Clostridia	K	Belongs to the ParB family	-	-	-	-	-	-	-	-	-	-	-	-	ParBc
HALNLLBL_01028	693746.OBV_34800	1.19e-06	48.1	COG3311@1|root,COG3311@2|Bacteria,1VKNA@1239|Firmicutes	1239|Firmicutes	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
HALNLLBL_01029	86416.Clopa_1675	7.55e-40	153.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,36F0S@31979|Clostridiaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_DNA,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase
HALNLLBL_01031	1461577.CCMH01000046_gene870	0.0	924.0	COG0286@1|root,COG0286@2|Bacteria,4NFQR@976|Bacteroidetes,1I0BR@117743|Flavobacteriia	976|Bacteroidetes	V	N-6 DNA Methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
HALNLLBL_01032	1437605.BACT_1132	2.09e-87	274.0	COG0732@1|root,COG0732@2|Bacteria,2IPXW@201174|Actinobacteria,4D0XX@85004|Bifidobacteriales	201174|Actinobacteria	V	Type I restriction modification DNA specificity domain	-	-	-	-	-	-	-	-	-	-	-	-	Methylase_S
HALNLLBL_01034	1122217.KB899613_gene1458	5.23e-274	758.0	COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,4H2WK@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase
HALNLLBL_01035	936596.HMPREF1495_2603	1.17e-50	167.0	COG2109@1|root,COG2109@2|Bacteria,1V70U@1239|Firmicutes,24JNB@186801|Clostridia,1HVMI@1164882|Lachnoanaerobaculum	186801|Clostridia	H	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP	btuR	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
HALNLLBL_01036	1105031.HMPREF1141_0349	1.27e-61	189.0	COG0051@1|root,COG0051@2|Bacteria,1V6C9@1239|Firmicutes,24JDC@186801|Clostridia,36JJY@31979|Clostridiaceae	186801|Clostridia	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
HALNLLBL_01037	428125.CLOLEP_01036	2.11e-116	337.0	COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,247NH@186801|Clostridia,3WHH0@541000|Ruminococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
HALNLLBL_01038	428125.CLOLEP_01035	9.3e-114	330.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,3WGQT@541000|Ruminococcaceae	186801|Clostridia	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
HALNLLBL_01039	428125.CLOLEP_01034	6.01e-39	132.0	COG0089@1|root,COG0089@2|Bacteria,1VA4W@1239|Firmicutes,24MN8@186801|Clostridia,3WJVK@541000|Ruminococcaceae	186801|Clostridia	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
HALNLLBL_01040	428125.CLOLEP_01033	6.52e-168	472.0	COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,247XY@186801|Clostridia,3WGQK@541000|Ruminococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
HALNLLBL_01041	1410617.JHXH01000003_gene549	9.8e-56	174.0	COG0185@1|root,COG0185@2|Bacteria,1V6CX@1239|Firmicutes,24JN3@186801|Clostridia,3WJ9F@541000|Ruminococcaceae	186801|Clostridia	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
HALNLLBL_01042	428125.CLOLEP_01031	2.1e-53	169.0	COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,24JF4@186801|Clostridia,3WJ9K@541000|Ruminococcaceae	186801|Clostridia	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
HALNLLBL_01043	428125.CLOLEP_01030	7.8e-123	354.0	COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,24833@186801|Clostridia,3WGIF@541000|Ruminococcaceae	186801|Clostridia	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
HALNLLBL_01044	428125.CLOLEP_01029	1.13e-86	256.0	COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,24FQX@186801|Clostridia,3WIIZ@541000|Ruminococcaceae	186801|Clostridia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
HALNLLBL_01045	428125.CLOLEP_01028	3.34e-23	90.1	COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,24QV1@186801|Clostridia,3WKVV@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
HALNLLBL_01046	1042156.CXIVA_17980	4.98e-44	144.0	COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,24MSW@186801|Clostridia,36KIV@31979|Clostridiaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
HALNLLBL_01047	428125.CLOLEP_01026	8.22e-76	227.0	COG0093@1|root,COG0093@2|Bacteria,1V3N0@1239|Firmicutes,24H98@186801|Clostridia,3WITX@541000|Ruminococcaceae	186801|Clostridia	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
HALNLLBL_01048	428125.CLOLEP_01025	4.2e-59	183.0	COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,24MY0@186801|Clostridia,3WJBH@541000|Ruminococcaceae	186801|Clostridia	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
HALNLLBL_01049	428125.CLOLEP_01024	3.11e-112	323.0	COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,247X0@186801|Clostridia,3WGYQ@541000|Ruminococcaceae	186801|Clostridia	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
HALNLLBL_01050	1121115.AXVN01000046_gene2971	1.14e-36	123.0	COG0199@1|root,COG0199@2|Bacteria,1VEF6@1239|Firmicutes,24QR1@186801|Clostridia,3Y0DU@572511|Blautia	186801|Clostridia	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
HALNLLBL_01051	1105031.HMPREF1141_0334	2.09e-76	229.0	COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,24HCP@186801|Clostridia,36I6W@31979|Clostridiaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
HALNLLBL_01052	428125.CLOLEP_01021	1.71e-94	279.0	COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,2496R@186801|Clostridia,3WIFT@541000|Ruminococcaceae	186801|Clostridia	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
HALNLLBL_01053	1105031.HMPREF1141_0332	1.46e-54	173.0	COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,24JCS@186801|Clostridia,36JQ0@31979|Clostridiaceae	186801|Clostridia	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
HALNLLBL_01054	1105031.HMPREF1141_0331	1.6e-89	265.0	COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,36DG4@31979|Clostridiaceae	186801|Clostridia	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
HALNLLBL_01055	428125.CLOLEP_01018	1.73e-25	95.1	COG1841@1|root,COG1841@2|Bacteria,1UG5U@1239|Firmicutes,24RUS@186801|Clostridia,3WKJT@541000|Ruminococcaceae	186801|Clostridia	J	ribosomal protein	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
HALNLLBL_01056	428125.CLOLEP_01017	4.38e-69	212.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia,3WIV7@541000|Ruminococcaceae	186801|Clostridia	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
HALNLLBL_01057	1105031.HMPREF1141_0328	4.88e-208	587.0	COG0201@1|root,COG0201@2|Bacteria,1TPHB@1239|Firmicutes,248T9@186801|Clostridia,36F8Y@31979|Clostridiaceae	186801|Clostridia	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
HALNLLBL_01058	1120746.CCNL01000017_gene2994	1.06e-109	320.0	COG0563@1|root,COG0563@2|Bacteria,2NPBU@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004017,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006412,GO:0006518,GO:0006629,GO:0006644,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0010467,GO:0015949,GO:0015950,GO:0015951,GO:0016070,GO:0016208,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019205,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iECH74115_1262.ECH74115_0566,iEKO11_1354.EKO11_3373,iG2583_1286.G2583_0586,iJN746.PP_1506	ADK,ADK_lid
HALNLLBL_01059	428125.CLOLEP_01014	2.39e-142	405.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia,3WGEW@541000|Ruminococcaceae	186801|Clostridia	E	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
HALNLLBL_01060	1160721.RBI_I01921	5.37e-15	70.9	COG2163@1|root,COG2163@2|Bacteria,1VEPA@1239|Firmicutes,24UP0@186801|Clostridia,3WKH3@541000|Ruminococcaceae	186801|Clostridia	J	COG2163 Ribosomal protein L14E L6E L27E	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01061	428125.CLOLEP_01012	1.32e-38	129.0	COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,24MQE@186801|Clostridia,3WK1D@541000|Ruminococcaceae	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
HALNLLBL_01062	888062.HMPREF9083_0929	5.8e-18	74.7	COG0257@1|root,COG0257@2|Bacteria,1VK4F@1239|Firmicutes,4H629@909932|Negativicutes	909932|Negativicutes	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
HALNLLBL_01063	428125.CLOLEP_01010	3.22e-73	220.0	COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia,3WJ08@541000|Ruminococcaceae	186801|Clostridia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
HALNLLBL_01064	428125.CLOLEP_01009	3.7e-73	221.0	COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,24HIK@186801|Clostridia,3WIYT@541000|Ruminococcaceae	186801|Clostridia	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
HALNLLBL_01065	742738.HMPREF9460_02000	1.2e-101	298.0	COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia,267UN@186813|unclassified Clostridiales	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
HALNLLBL_01066	428125.CLOLEP_01007	6.18e-185	519.0	COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,248DS@186801|Clostridia,3WGUM@541000|Ruminococcaceae	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
HALNLLBL_01067	1120746.CCNL01000017_gene2986	1.26e-59	185.0	COG0203@1|root,COG0203@2|Bacteria,2NPYQ@2323|unclassified Bacteria	2|Bacteria	J	Ribosomal protein L17	rplQ	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02879,ko:K16193	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
HALNLLBL_01069	658086.HMPREF0994_01376	1.15e-32	141.0	COG1705@1|root,COG1705@2|Bacteria,1UMKN@1239|Firmicutes,25GKA@186801|Clostridia,27IXC@186928|unclassified Lachnospiraceae	186801|Clostridia	NU	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH
HALNLLBL_01070	1410617.JHXH01000007_gene1515	2.63e-129	390.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,2489V@186801|Clostridia,3WH1A@541000|Ruminococcaceae	186801|Clostridia	G	Pyruvate kinase	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
HALNLLBL_01071	622312.ROSEINA2194_01457	2.76e-51	169.0	COG0703@1|root,COG0703@2|Bacteria,1V3W6@1239|Firmicutes,24HKA@186801|Clostridia	186801|Clostridia	E	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
HALNLLBL_01072	1120746.CCNL01000017_gene3031	1.61e-129	383.0	COG0077@1|root,COG0077@2|Bacteria,2NR2C@2323|unclassified Bacteria	2|Bacteria	E	Prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
HALNLLBL_01073	1121334.KB911071_gene2137	5.16e-158	454.0	COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,24998@186801|Clostridia,3WG94@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
HALNLLBL_01074	1120746.CCNL01000017_gene3029	5.12e-147	431.0	COG0128@1|root,COG0128@2|Bacteria,2NNZ5@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
HALNLLBL_01075	428125.CLOLEP_03744	1.67e-126	374.0	COG0337@1|root,COG0337@2|Bacteria,1TPKZ@1239|Firmicutes,248H4@186801|Clostridia,3WGPK@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
HALNLLBL_01076	428125.CLOLEP_03745	5.31e-119	348.0	COG0287@1|root,COG0287@2|Bacteria,1TPXG@1239|Firmicutes,248KX@186801|Clostridia,3WI06@541000|Ruminococcaceae	186801|Clostridia	E	prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
HALNLLBL_01077	428125.CLOLEP_03746	8.13e-187	525.0	COG2876@1|root,COG2876@2|Bacteria,1TP61@1239|Firmicutes,24812@186801|Clostridia,3WG9J@541000|Ruminococcaceae	186801|Clostridia	E	synthase	aroF	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS14395	DAHP_synth_1
HALNLLBL_01078	428125.CLOLEP_03749	6.55e-56	181.0	COG0703@1|root,COG0703@2|Bacteria,1VA6Z@1239|Firmicutes,24MQY@186801|Clostridia,3WJBW@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,SKI
HALNLLBL_01079	428125.CLOLEP_03750	2.41e-98	296.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia,3WGF4@541000|Ruminococcaceae	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI,Shikimate_DH,Shikimate_dh_N
HALNLLBL_01080	428125.CLOLEP_03751	7.02e-33	115.0	COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,24QME@186801|Clostridia,3WKU1@541000|Ruminococcaceae	186801|Clostridia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
HALNLLBL_01081	428125.CLOLEP_03755	2.89e-262	728.0	COG0441@1|root,COG0441@2|Bacteria,1UHT4@1239|Firmicutes,25E98@186801|Clostridia,3WHAG@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
HALNLLBL_01082	428125.CLOLEP_02491	8.71e-160	454.0	COG1897@1|root,COG1897@2|Bacteria,1TQVR@1239|Firmicutes,247NP@186801|Clostridia,3WGY0@541000|Ruminococcaceae	186801|Clostridia	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metAA	-	2.3.1.46	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	M00017	R01777	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS11970	AA_kinase,HTS
HALNLLBL_01083	428125.CLOLEP_01053	2.36e-118	346.0	COG0263@1|root,COG0263@2|Bacteria,1TPG6@1239|Firmicutes,2486P@186801|Clostridia,3WGZ7@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
HALNLLBL_01084	428125.CLOLEP_01052	4.57e-203	573.0	COG0014@1|root,COG0014@2|Bacteria,1TQ9V@1239|Firmicutes,248NX@186801|Clostridia,3WH60@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
HALNLLBL_01086	428125.CLOLEP_01049	3.38e-12	66.6	2EH2J@1|root,33AUH@2|Bacteria,1VP6D@1239|Firmicutes,24QT3@186801|Clostridia,3WM9M@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01088	1105031.HMPREF1141_1852	2.67e-46	155.0	COG0622@1|root,COG0622@2|Bacteria,1VA0U@1239|Firmicutes,24MMK@186801|Clostridia,36J2K@31979|Clostridiaceae	186801|Clostridia	S	Phosphoesterase	yfcE1	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
HALNLLBL_01089	1511.CLOST_2146	1.34e-15	82.8	COG0470@1|root,COG0470@2|Bacteria,1TRVS@1239|Firmicutes,25E6M@186801|Clostridia,25TBY@186804|Peptostreptococcaceae	186801|Clostridia	L	DNA polymerase III, delta subunit	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
HALNLLBL_01090	428125.CLOLEP_03761	2.8e-148	424.0	COG1774@1|root,COG1774@2|Bacteria,1TP1V@1239|Firmicutes,247Q6@186801|Clostridia,3WHA4@541000|Ruminococcaceae	186801|Clostridia	S	PSP1 C-terminal domain protein	yaaT	-	-	-	-	-	-	-	-	-	-	-	PSP1
HALNLLBL_01091	645991.Sgly_0634	3.55e-11	58.9	COG4231@1|root,COG4231@2|Bacteria,1UIUE@1239|Firmicutes,25ES8@186801|Clostridia,267EQ@186807|Peptococcaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
HALNLLBL_01092	1235835.C814_00280	1.56e-65	211.0	COG4123@1|root,COG4123@2|Bacteria,1TQ25@1239|Firmicutes,24J47@186801|Clostridia,3WRTS@541000|Ruminococcaceae	186801|Clostridia	S	Methyltransferase small domain	-	-	-	-	-	-	-	-	-	-	-	-	MTS
HALNLLBL_01093	1120746.CCNL01000017_gene3223	5.53e-130	376.0	COG0313@1|root,COG0313@2|Bacteria,2NP98@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
HALNLLBL_01094	1120746.CCNL01000014_gene2038	1.06e-135	403.0	COG0285@1|root,COG0285@2|Bacteria,2NP60@2323|unclassified Bacteria	2|Bacteria	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
HALNLLBL_01095	537013.CLOSTMETH_03322	6.94e-28	104.0	COG1366@1|root,COG1366@2|Bacteria,1VENG@1239|Firmicutes,24R0X@186801|Clostridia,3WKRQ@541000|Ruminococcaceae	186801|Clostridia	T	Belongs to the anti-sigma-factor antagonist family	spoIIAA	-	-	ko:K06378	-	-	-	-	ko00000	-	-	-	STAS
HALNLLBL_01096	1235835.C814_00667	1.52e-57	182.0	COG2172@1|root,COG2172@2|Bacteria,1V6V2@1239|Firmicutes,24JPT@186801|Clostridia,3WJC6@541000|Ruminococcaceae	186801|Clostridia	T	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition	spoIIAB	-	2.7.11.1	ko:K06379	-	-	-	-	ko00000,ko01000	-	-	-	HATPase_c_2
HALNLLBL_01097	1410617.JHXH01000005_gene1104	4.17e-73	228.0	COG1191@1|root,COG1191@2|Bacteria,1V296@1239|Firmicutes,24GTU@186801|Clostridia,3WGPV@541000|Ruminococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family	sigF	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
HALNLLBL_01099	1235797.C816_03924	3.34e-22	90.5	COG1476@1|root,COG1476@2|Bacteria,1VEKB@1239|Firmicutes,25F54@186801|Clostridia	186801|Clostridia	K	PFAM helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
HALNLLBL_01100	428125.CLOLEP_02385	4.92e-116	343.0	COG1281@1|root,COG1281@2|Bacteria,1TRCH@1239|Firmicutes,24940@186801|Clostridia,3WHW9@541000|Ruminococcaceae	186801|Clostridia	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
HALNLLBL_01101	428125.CLOLEP_02384	1.32e-89	272.0	COG0500@1|root,COG2226@2|Bacteria,1TQUF@1239|Firmicutes,25E3F@186801|Clostridia,3WIFZ@541000|Ruminococcaceae	186801|Clostridia	Q	Methyltransferase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
HALNLLBL_01102	1195236.CTER_3851	1.63e-33	118.0	COG4496@1|root,COG4496@2|Bacteria,1VA04@1239|Firmicutes,24MX9@186801|Clostridia,3WKB9@541000|Ruminococcaceae	186801|Clostridia	S	protein, YerC YecD	-	-	-	-	-	-	-	-	-	-	-	-	Trp_repressor
HALNLLBL_01103	1105031.HMPREF1141_0185	2.32e-140	401.0	COG1191@1|root,COG1191@2|Bacteria,1TPDD@1239|Firmicutes,24A1H@186801|Clostridia,36E0E@31979|Clostridiaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigG	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
HALNLLBL_01104	411463.EUBVEN_02375	1.69e-37	130.0	COG1725@1|root,COG1725@2|Bacteria,1VFD0@1239|Firmicutes,24MTU@186801|Clostridia,25X79@186806|Eubacteriaceae	186801|Clostridia	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
HALNLLBL_01105	1105031.HMPREF1141_2031	4.91e-109	325.0	COG1131@1|root,COG1131@2|Bacteria,1TPQW@1239|Firmicutes,248F7@186801|Clostridia,36DSS@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter	ytrB	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HALNLLBL_01106	1120746.CCNL01000017_gene2947	1.19e-18	99.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
HALNLLBL_01107	1282887.AUJG01000001_gene1541	8.53e-95	280.0	COG3760@1|root,COG3760@2|Bacteria,1V1JF@1239|Firmicutes,24FVD@186801|Clostridia	186801|Clostridia	J	YbaK proline--tRNA ligase associated domain protein	-	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
HALNLLBL_01109	138119.DSY2434	2.04e-36	151.0	COG0642@1|root,COG2205@2|Bacteria,1VBSG@1239|Firmicutes,24KQZ@186801|Clostridia,263WU@186807|Peptococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
HALNLLBL_01110	138119.DSY2435	1.08e-79	246.0	COG0745@1|root,COG0745@2|Bacteria,1V21C@1239|Firmicutes,24GEM@186801|Clostridia,264DW@186807|Peptococcaceae	186801|Clostridia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HALNLLBL_01111	1226322.HMPREF1545_02484	5.72e-50	163.0	COG0517@1|root,COG0517@2|Bacteria,1V7XE@1239|Firmicutes,24HF5@186801|Clostridia,2N7DV@216572|Oscillospiraceae	186801|Clostridia	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
HALNLLBL_01113	1124982.MSI_13600	1.58e-88	263.0	2DBP0@1|root,2ZA6P@2|Bacteria,2J7V8@203691|Spirochaetes	203691|Spirochaetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01114	1120746.CCNL01000017_gene2958	4.04e-42	158.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
HALNLLBL_01115	585394.RHOM_10215	0.0	952.0	COG0369@1|root,COG1151@2|Bacteria,1TP8X@1239|Firmicutes,247IN@186801|Clostridia	186801|Clostridia	C	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O	hcp	-	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	-	Prismane
HALNLLBL_01116	1121335.Clst_2206	9.26e-72	245.0	COG2898@1|root,COG2898@2|Bacteria,1U5FR@1239|Firmicutes,248XI@186801|Clostridia,3WIHF@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran_2
HALNLLBL_01117	633697.EubceDRAFT1_1554	6.48e-130	374.0	COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,248WG@186801|Clostridia,25W6H@186806|Eubacteriaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HALNLLBL_01118	1160721.RBI_I01635	1.36e-93	280.0	COG1272@1|root,COG1272@2|Bacteria,1TSFK@1239|Firmicutes,24CPT@186801|Clostridia,3WIMP@541000|Ruminococcaceae	186801|Clostridia	S	protein, hemolysin III	-	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
HALNLLBL_01119	357809.Cphy_2825	4.21e-227	648.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,247KT@186801|Clostridia,21XXW@1506553|Lachnoclostridium	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
HALNLLBL_01120	180332.JTGN01000012_gene279	5.04e-124	382.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia	186801|Clostridia	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,sCache_like
HALNLLBL_01121	357809.Cphy_2827	1.48e-89	270.0	COG0745@1|root,COG0745@2|Bacteria,1TQY9@1239|Firmicutes,24D6A@186801|Clostridia,22457@1506553|Lachnoclostridium	186801|Clostridia	K	response regulator receiver	phoB	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HALNLLBL_01122	1232443.BAIA02000126_gene1108	1.33e-63	203.0	COG0704@1|root,COG0704@2|Bacteria,1URN3@1239|Firmicutes,24FTM@186801|Clostridia,268P9@186813|unclassified Clostridiales	186801|Clostridia	P	Plays a role in the regulation of phosphate uptake	phoU	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
HALNLLBL_01123	1121115.AXVN01000010_gene2779	2.61e-146	416.0	COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,247RD@186801|Clostridia,3XYGV@572511|Blautia	186801|Clostridia	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
HALNLLBL_01124	622312.ROSEINA2194_04398	3.82e-124	363.0	COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,248C4@186801|Clostridia	186801|Clostridia	P	phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
HALNLLBL_01125	1232443.BAIA02000126_gene1111	1.7e-135	392.0	COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,249KQ@186801|Clostridia,267YJ@186813|unclassified Clostridiales	186801|Clostridia	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
HALNLLBL_01126	411474.COPEUT_02135	6.48e-101	305.0	COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,248QU@186801|Clostridia	186801|Clostridia	P	phosphate binding protein	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
HALNLLBL_01127	1280679.ATVX01000002_gene807	6.3e-295	809.0	COG1350@1|root,COG1350@2|Bacteria,1UI01@1239|Firmicutes,25E8Q@186801|Clostridia,4BWG1@830|Butyrivibrio	186801|Clostridia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
HALNLLBL_01129	1120746.CCNL01000014_gene2198	9.48e-223	627.0	COG0064@1|root,COG0064@2|Bacteria,2NNPK@2323|unclassified Bacteria	2|Bacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.12,6.3.5.6,6.3.5.7	ko:K01876,ko:K02434	ko00970,ko01100,map00970,map01100	M00359,M00360	R03905,R04212,R05577	RC00010,RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GatB_N,GatB_Yqey
HALNLLBL_01130	1120746.CCNL01000014_gene2197	2.17e-244	683.0	COG0154@1|root,COG0154@2|Bacteria,2NNSD@2323|unclassified Bacteria	2|Bacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
HALNLLBL_01131	1105031.HMPREF1141_0202	3.49e-22	89.4	COG0721@1|root,COG0721@2|Bacteria	2|Bacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	iAF987.Gmet_0076	Glu-tRNAGln
HALNLLBL_01132	1105031.HMPREF1141_0201	2.14e-316	874.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,247Z3@186801|Clostridia,36EHV@31979|Clostridiaceae	186801|Clostridia	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
HALNLLBL_01133	1280689.AUJC01000008_gene2943	1.8e-175	551.0	COG0577@1|root,COG1511@1|root,COG0577@2|Bacteria,COG1511@2|Bacteria,1TPHU@1239|Firmicutes,248RV@186801|Clostridia,36E94@31979|Clostridiaceae	186801|Clostridia	V	Permease	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HALNLLBL_01134	903814.ELI_1949	3.64e-117	340.0	COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,248Z6@186801|Clostridia,25V4X@186806|Eubacteriaceae	186801|Clostridia	V	ABC-type antimicrobial peptide transport system, ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HALNLLBL_01135	428125.CLOLEP_00759	8.79e-107	311.0	COG1573@1|root,COG1573@2|Bacteria,1V267@1239|Firmicutes,24DFW@186801|Clostridia,3WIGX@541000|Ruminococcaceae	186801|Clostridia	L	Uracil-DNA glycosylase	udgA	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
HALNLLBL_01136	428125.CLOLEP_00762	4.62e-96	283.0	COG4869@1|root,COG4869@2|Bacteria,1V242@1239|Firmicutes,24EHP@186801|Clostridia,3WRUR@541000|Ruminococcaceae	186801|Clostridia	Q	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate	-	-	2.3.1.8	ko:K15024	ko00430,ko00620,ko00640,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00720,map01100,map01120,map01200	M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTAC
HALNLLBL_01137	411461.DORFOR_02735	2.63e-23	97.8	2ECPC@1|root,336M5@2|Bacteria,1VIMI@1239|Firmicutes,24QHI@186801|Clostridia	186801|Clostridia	S	YcxB-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YcxB
HALNLLBL_01138	1034807.FBFL15_1362	5.39e-34	130.0	COG2819@1|root,COG2819@2|Bacteria,4NH6C@976|Bacteroidetes,1HY0J@117743|Flavobacteriia,2NUQN@237|Flavobacterium	976|Bacteroidetes	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
HALNLLBL_01139	553973.CLOHYLEM_06959	1.04e-11	66.2	2BVD7@1|root,32QT8@2|Bacteria,1V6S8@1239|Firmicutes,24JJP@186801|Clostridia,2215X@1506553|Lachnoclostridium	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01140	1160721.RBI_II00479	0.0	987.0	COG1866@1|root,COG1866@2|Bacteria,1TPQV@1239|Firmicutes,248JE@186801|Clostridia,3WGXZ@541000|Ruminococcaceae	186801|Clostridia	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
HALNLLBL_01141	699246.HMPREF0868_1272	2.77e-48	157.0	COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,269AI@186813|unclassified Clostridiales	186801|Clostridia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
HALNLLBL_01142	1235835.C814_02957	1.65e-46	157.0	COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,24G9R@186801|Clostridia,3WIH7@541000|Ruminococcaceae	186801|Clostridia	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
HALNLLBL_01143	1121334.KB911074_gene2487	8.24e-136	387.0	COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,3WH4A@541000|Ruminococcaceae	186801|Clostridia	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
HALNLLBL_01144	1105031.HMPREF1141_0709	2.78e-83	247.0	COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,24FSQ@186801|Clostridia,36I00@31979|Clostridiaceae	186801|Clostridia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
HALNLLBL_01145	428125.CLOLEP_02931	2.35e-84	253.0	COG0250@1|root,COG0250@2|Bacteria,1TR3P@1239|Firmicutes,248XB@186801|Clostridia,3WJ0G@541000|Ruminococcaceae	186801|Clostridia	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
HALNLLBL_01146	883.DvMF_1449	0.000318	43.1	COG0690@1|root,COG0690@2|Bacteria,1Q1BI@1224|Proteobacteria,42X4Z@68525|delta/epsilon subdivisions,2WSQ8@28221|Deltaproteobacteria,2MD79@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
HALNLLBL_01147	1105031.HMPREF1141_0706	1.22e-26	97.4	COG0267@1|root,COG0267@2|Bacteria,1VEJ4@1239|Firmicutes,24QK0@186801|Clostridia,36MJQ@31979|Clostridiaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
HALNLLBL_01148	428125.CLOLEP_02928	2.99e-56	188.0	2C2S8@1|root,33RGY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01149	1120746.CCNL01000009_gene1028	3.63e-112	331.0	COG0796@1|root,COG0796@2|Bacteria,2NP3D@2323|unclassified Bacteria	2|Bacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
HALNLLBL_01150	1121335.Clst_2422	3.37e-12	67.4	COG4506@1|root,COG4506@2|Bacteria,1U49U@1239|Firmicutes,259FV@186801|Clostridia,3WKB8@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF1934)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1934
HALNLLBL_01151	1120746.CCNL01000009_gene1026	5.09e-278	775.0	COG0018@1|root,COG0018@2|Bacteria,2NNSE@2323|unclassified Bacteria	2|Bacteria	J	Arginyl tRNA synthetase N terminal dom	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iAF987.Gmet_1434	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
HALNLLBL_01152	1122918.KB907274_gene3468	1.1e-09	66.2	COG2755@1|root,COG5272@1|root,COG5492@1|root,COG2755@2|Bacteria,COG5272@2|Bacteria,COG5492@2|Bacteria,1TS8J@1239|Firmicutes,4IU56@91061|Bacilli,26ZHU@186822|Paenibacillaceae	91061|Bacilli	N	Leucine rich repeats (6 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Big_3,Cadherin-like,DUF5011,Flg_new,LRR_5,SLH,fn3,ubiquitin
HALNLLBL_01153	1232443.BAIA02000055_gene1297	7.21e-25	94.7	COG1396@1|root,COG1396@2|Bacteria,1VF2C@1239|Firmicutes,24RJU@186801|Clostridia,26BTW@186813|unclassified Clostridiales	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
HALNLLBL_01154	877414.ATWA01000083_gene1334	3.6e-19	99.4	COG3209@1|root,COG5492@1|root,COG3209@2|Bacteria,COG5492@2|Bacteria,1UWE7@1239|Firmicutes,25KT8@186801|Clostridia,26BGT@186813|unclassified Clostridiales	2|Bacteria	MN	Fibronectin type 3 domain	-	-	2.4.1.10,3.5.1.28	ko:K00692,ko:K01448,ko:K13730	ko00500,ko01100,ko01503,ko02020,ko05100,map00500,map01100,map01503,map02020,map05100	M00727	R04112,R05140	RC00064,RC00077,RC00141	ko00000,ko00001,ko00002,ko01000,ko01003,ko01011,ko03036	-	GH68	-	ALF,Big_2,ChW,PT-HINT,Ricin_B_lectin
HALNLLBL_01156	641112.ACOK01000055_gene3805	1.18e-42	152.0	COG1434@1|root,COG1434@2|Bacteria,1VA42@1239|Firmicutes,24HKK@186801|Clostridia,3WIGF@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
HALNLLBL_01157	1121115.AXVN01000104_gene843	9.03e-242	679.0	COG0437@1|root,COG4624@1|root,COG0437@2|Bacteria,COG4624@2|Bacteria,1TQIR@1239|Firmicutes,248BS@186801|Clostridia,3XYSR@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Fe_hyd_lg_C,Fer4,Fer4_6
HALNLLBL_01159	511680.BUTYVIB_00741	7.62e-157	441.0	2DGBS@1|root,2ZVBF@2|Bacteria,1W5KM@1239|Firmicutes,2570Z@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01160	428125.CLOLEP_02725	3.28e-131	378.0	COG0825@1|root,COG0825@2|Bacteria,1UHNS@1239|Firmicutes,25E47@186801|Clostridia,3WSKG@541000|Ruminococcaceae	186801|Clostridia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
HALNLLBL_01161	428125.CLOLEP_02724	2.44e-125	367.0	COG0777@1|root,COG0777@2|Bacteria,1TP4U@1239|Firmicutes,248QK@186801|Clostridia,3WGZ8@541000|Ruminococcaceae	186801|Clostridia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
HALNLLBL_01162	1120746.CCNL01000006_gene337	5.53e-221	621.0	COG0439@1|root,COG0439@2|Bacteria,2NNWM@2323|unclassified Bacteria	2|Bacteria	I	acetyl-CoA carboxylase, biotin carboxylase	accC	GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iSF_1195.SF3294	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
HALNLLBL_01163	428125.CLOLEP_02721	2.66e-62	194.0	COG0764@1|root,COG0764@2|Bacteria,1V6EX@1239|Firmicutes,24JAW@186801|Clostridia	186801|Clostridia	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
HALNLLBL_01164	1297581.H919_00735	8.46e-32	118.0	COG0511@1|root,COG0511@2|Bacteria,1VAB7@1239|Firmicutes,4HKCS@91061|Bacilli,21VPM@150247|Anoxybacillus	91061|Bacilli	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
HALNLLBL_01165	1120746.CCNL01000006_gene340	1.09e-187	533.0	COG0304@1|root,COG0304@2|Bacteria,2NNSX@2323|unclassified Bacteria	2|Bacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179,2.3.1.41	ko:K00647,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
HALNLLBL_01166	428125.CLOLEP_02718	1.38e-114	335.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,3WGIW@541000|Ruminococcaceae	186801|Clostridia	IQ	reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
HALNLLBL_01167	428125.CLOLEP_02717	2.51e-125	367.0	COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,247UF@186801|Clostridia,3WGWD@541000|Ruminococcaceae	186801|Clostridia	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
HALNLLBL_01168	1120746.CCNL01000006_gene344	1.59e-142	411.0	COG2070@1|root,COG2070@2|Bacteria,2NPGR@2323|unclassified Bacteria	2|Bacteria	S	Nitronate monooxygenase	fabK	-	1.3.1.9	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iHN637.CLJU_RS20775	NMO
HALNLLBL_01170	1105031.HMPREF1141_1042	1.49e-192	576.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,248A4@186801|Clostridia,36E3C@31979|Clostridiaceae	186801|Clostridia	M	penicillin-binding protein 1A	mrcB	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
HALNLLBL_01171	1121334.KB911073_gene1930	6.37e-181	516.0	COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,248MU@186801|Clostridia,3WGG4@541000|Ruminococcaceae	186801|Clostridia	E	homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
HALNLLBL_01172	428125.CLOLEP_02735	3.84e-222	620.0	COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,24811@186801|Clostridia,3WHC9@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
HALNLLBL_01173	1336241.JAEB01000021_gene1730	1.46e-50	190.0	COG5279@1|root,COG5279@2|Bacteria,1V8TE@1239|Firmicutes,24CI3@186801|Clostridia,25XC1@186806|Eubacteriaceae	186801|Clostridia	D	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CW_binding_2,Cu_amine_oxidN1,Transglut_core
HALNLLBL_01174	428125.CLOLEP_00331	2.6e-33	117.0	COG1609@1|root,COG1609@2|Bacteria,1VADF@1239|Firmicutes,24MXI@186801|Clostridia,3WKHX@541000|Ruminococcaceae	186801|Clostridia	K	sporulation transcriptional regulator SpoIIID	spoIIID	-	-	ko:K06283	-	-	-	-	ko00000,ko03000	-	-	-	SpoIIID
HALNLLBL_01175	435591.BDI_1838	2.04e-192	545.0	COG0399@1|root,COG0399@2|Bacteria,4NFQ8@976|Bacteroidetes,2FMKJ@200643|Bacteroidia,22ZYB@171551|Porphyromonadaceae	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.59	ko:K02805	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	DegT_DnrJ_EryC1
HALNLLBL_01176	1408323.JQKK01000012_gene880	1.31e-05	48.1	2BCWF@1|root,326H8@2|Bacteria,1USE0@1239|Firmicutes,25AD7@186801|Clostridia,27Q7W@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01177	1120746.CCNL01000014_gene2185	1.72e-62	207.0	COG0679@1|root,COG0679@2|Bacteria	2|Bacteria	S	auxin-activated signaling pathway	mleP3	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
HALNLLBL_01178	411468.CLOSCI_03507	2.28e-118	351.0	COG2378@1|root,COG2378@2|Bacteria,1TSA2@1239|Firmicutes,247S2@186801|Clostridia,21Z34@1506553|Lachnoclostridium	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	WYL
HALNLLBL_01179	663952.SDD27957_04550	4.79e-28	117.0	COG2207@1|root,COG2207@2|Bacteria,1UZG6@1239|Firmicutes,4HCQS@91061|Bacilli,1M9XV@119603|Streptococcus dysgalactiae group	91061|Bacilli	K	AraC-type DNA-binding domain-containing proteins	bglC	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
HALNLLBL_01181	702450.CUW_1624	9.31e-66	221.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,3VPKC@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
HALNLLBL_01182	428125.CLOLEP_03715	2.14e-56	194.0	COG0110@1|root,COG0110@2|Bacteria,1V23V@1239|Firmicutes,24GGM@186801|Clostridia,3WJ74@541000|Ruminococcaceae	186801|Clostridia	S	COG COG0110 Acetyltransferase (isoleucine patch superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	ATPgrasp_ST
HALNLLBL_01183	1319815.HMPREF0202_02746	1.99e-10	72.4	COG1479@1|root,COG1479@2|Bacteria	2|Bacteria	U	Protein of unknown function DUF262	-	-	-	-	-	-	-	-	-	-	-	-	DUF1524,DUF262
HALNLLBL_01184	1354300.AUQY01000002_gene562	1.65e-38	155.0	29ZFD@1|root,30MET@2|Bacteria,1V8PZ@1239|Firmicutes,24GM3@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01185	1033737.CAEV01000062_gene2983	6.08e-36	130.0	COG0671@1|root,COG0671@2|Bacteria,1V7XD@1239|Firmicutes,25BF5@186801|Clostridia,36WGI@31979|Clostridiaceae	186801|Clostridia	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
HALNLLBL_01186	428125.CLOLEP_02457	2.63e-139	405.0	COG0183@1|root,COG0183@2|Bacteria,1UHVW@1239|Firmicutes,248BM@186801|Clostridia,3WSI5@541000|Ruminococcaceae	186801|Clostridia	I	Stage V sporulation protein AD	spoVAD	-	-	ko:K06406	-	-	-	-	ko00000	-	-	-	SpoVAD
HALNLLBL_01187	428125.CLOLEP_00382	4.82e-54	199.0	COG2720@1|root,COG2720@2|Bacteria,1TSH8@1239|Firmicutes,2493X@186801|Clostridia,3WRXM@541000|Ruminococcaceae	186801|Clostridia	V	VanW like protein	vanW	-	-	ko:K18346	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	G5,PG_binding_4,VanW
HALNLLBL_01188	1105031.HMPREF1141_1725	4.58e-104	319.0	COG0707@1|root,COG0707@2|Bacteria,1UQ6A@1239|Firmicutes,248FR@186801|Clostridia,36F7T@31979|Clostridiaceae	186801|Clostridia	M	Monogalactosyldiacylglycerol synthase	-	-	2.4.1.315	ko:K03429	ko00561,ko01100,map00561,map01100	-	R02689,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,MGDG_synth
HALNLLBL_01189	509191.AEDB02000042_gene4898	4.92e-22	105.0	COG4826@1|root,COG4826@2|Bacteria,1UYKX@1239|Firmicutes,24B76@186801|Clostridia,3WGCD@541000|Ruminococcaceae	186801|Clostridia	O	Belongs to the serpin family	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Dockerin_1,Serpin
HALNLLBL_01190	428125.CLOLEP_01561	5.87e-281	776.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,3WGJQ@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
HALNLLBL_01191	1120746.CCNL01000011_gene1544	0.0	929.0	COG0008@1|root,COG0008@2|Bacteria,2NNRW@2323|unclassified Bacteria	2|Bacteria	J	tRNA synthetases class I (E and Q), anti-codon binding domain	glnS	GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iECIAI39_1322.ECIAI39_0637	tRNA-synt_1c,tRNA-synt_1c_C
HALNLLBL_01192	1121334.KB911067_gene286	3.59e-92	278.0	COG1028@1|root,COG1028@2|Bacteria,1TZY6@1239|Firmicutes,248QZ@186801|Clostridia,3WIP8@541000|Ruminococcaceae	186801|Clostridia	IQ	Oxidoreductase, short chain dehydrogenase reductase family protein	fabG5	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
HALNLLBL_01193	1121334.KB911077_gene2436	1.43e-205	585.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia,3WHE3@541000|Ruminococcaceae	186801|Clostridia	M	acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HALNLLBL_01194	1410650.JHWL01000013_gene443	8.35e-61	211.0	COG2182@1|root,COG2182@2|Bacteria,1VRPK@1239|Firmicutes,24YZ4@186801|Clostridia,4BX85@830|Butyrivibrio	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K15770	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	SBP_bac_8
HALNLLBL_01195	1499683.CCFF01000016_gene784	1.86e-162	476.0	COG1175@1|root,COG1175@2|Bacteria,1TR2A@1239|Firmicutes,247MA@186801|Clostridia,36E1M@31979|Clostridiaceae	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K15771	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
HALNLLBL_01196	699246.HMPREF0868_0183	5.17e-122	357.0	COG3833@1|root,COG3833@2|Bacteria,1TRB7@1239|Firmicutes,248A7@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K15772	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
HALNLLBL_01197	642492.Clole_2971	1.76e-123	379.0	COG0366@1|root,COG0366@2|Bacteria,1TSEA@1239|Firmicutes,248HJ@186801|Clostridia	186801|Clostridia	G	Alpha amylase catalytic	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459
HALNLLBL_01198	428125.CLOLEP_03944	5.61e-87	256.0	COG0048@1|root,COG0048@2|Bacteria,1V1FJ@1239|Firmicutes,24FQT@186801|Clostridia,3WIHG@541000|Ruminococcaceae	186801|Clostridia	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
HALNLLBL_01199	1105031.HMPREF1141_0841	6.57e-96	280.0	COG0049@1|root,COG0049@2|Bacteria,1V1GG@1239|Firmicutes,24FQN@186801|Clostridia,36DC5@31979|Clostridiaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
HALNLLBL_01200	428125.CLOLEP_03946	0.0	1148.0	COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,3WGEG@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
HALNLLBL_01201	1120746.CCNL01000011_gene1565	2.07e-264	727.0	COG0050@1|root,COG0050@2|Bacteria,2NNQV@2323|unclassified Bacteria	2|Bacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
HALNLLBL_01203	1408323.JQKK01000002_gene1839	8.94e-142	404.0	COG1476@1|root,COG1476@2|Bacteria,1UUSK@1239|Firmicutes,247YW@186801|Clostridia,27KQ6@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Putative zinc ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Zn_ribbon_2
HALNLLBL_01204	428125.CLOLEP_02456	1e-51	169.0	2ANER@1|root,31DDD@2|Bacteria,1V46U@1239|Firmicutes,24JDI@186801|Clostridia,3WJNA@541000|Ruminococcaceae	186801|Clostridia	S	stage V sporulation protein AC	spoVAC	-	-	ko:K06405	-	-	-	-	ko00000	-	-	-	SpoVAC_SpoVAEB
HALNLLBL_01205	1120746.CCNL01000004_gene82	1.08e-134	396.0	COG1104@1|root,COG1104@2|Bacteria	2|Bacteria	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
HALNLLBL_01206	428125.CLOLEP_01204	5.1e-173	495.0	COG0301@1|root,COG0301@2|Bacteria,1TPNW@1239|Firmicutes,247Y5@186801|Clostridia,3WGMK@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	thiI	-	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	-	THUMP,ThiI
HALNLLBL_01207	1120746.CCNL01000004_gene85	7.46e-70	238.0	COG4509@1|root,COG4509@2|Bacteria	2|Bacteria	S	Sortase family	srtB	-	3.4.22.70	ko:K08600	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	CinA,MoCF_biosynth,Sortase,SpoIID
HALNLLBL_01209	411473.RUMCAL_01858	1.08e-255	704.0	COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,25E6I@186801|Clostridia,3WIMR@541000|Ruminococcaceae	186801|Clostridia	E	Cys Met metabolism	megL	-	2.5.1.48,4.4.1.11	ko:K01739,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00999,R01288,R02508,R03217,R03260,R04770,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00420,RC01209,RC01210,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
HALNLLBL_01211	556261.HMPREF0240_03718	3.45e-126	374.0	COG0739@1|root,COG0739@2|Bacteria,1TQMQ@1239|Firmicutes,24B3J@186801|Clostridia,36G4K@31979|Clostridiaceae	186801|Clostridia	M	Peptidase family M23	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
HALNLLBL_01213	742738.HMPREF9460_00707	1.36e-172	499.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,248V4@186801|Clostridia,268JH@186813|unclassified Clostridiales	186801|Clostridia	M	MBOAT, membrane-bound O-acyltransferase family	algI	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
HALNLLBL_01214	1408437.JNJN01000003_gene1583	9.07e-71	233.0	28IAA@1|root,2Z8CW@2|Bacteria,1TQHP@1239|Firmicutes,248TG@186801|Clostridia,25WPI@186806|Eubacteriaceae	186801|Clostridia	S	DHHW protein	-	-	-	-	-	-	-	-	-	-	-	-	DHHW
HALNLLBL_01216	537013.CLOSTMETH_03813	4.51e-116	354.0	COG0534@1|root,COG0534@2|Bacteria,1TPPJ@1239|Firmicutes,25AZE@186801|Clostridia,3WH9E@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HALNLLBL_01217	1321778.HMPREF1982_04469	3.49e-57	187.0	COG0637@1|root,COG0637@2|Bacteria,1VA5Z@1239|Firmicutes,24JNY@186801|Clostridia	186801|Clostridia	G	IA, variant 3	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
HALNLLBL_01218	428125.CLOLEP_02455	0.0	1917.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3WH0Y@541000|Ruminococcaceae	186801|Clostridia	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
HALNLLBL_01219	1449050.JNLE01000005_gene4007	4.27e-62	215.0	COG1376@1|root,COG1376@2|Bacteria,1UK0I@1239|Firmicutes,249X8@186801|Clostridia,36W7I@31979|Clostridiaceae	186801|Clostridia	M	L,D-transpeptidase catalytic domain	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Cu_amine_oxidN1,DUF5011,YkuD
HALNLLBL_01220	1160721.RBI_I00418	5.18e-80	242.0	2943S@1|root,2ZRIE@2|Bacteria,1V3J6@1239|Firmicutes,24HEP@186801|Clostridia,3WICX@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	KatE	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01221	1105031.HMPREF1141_1748	7.98e-64	200.0	COG1418@1|root,COG1418@2|Bacteria,1V70P@1239|Firmicutes,24JTJ@186801|Clostridia,36FE1@31979|Clostridiaceae	186801|Clostridia	S	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
HALNLLBL_01222	1256908.HMPREF0373_02733	0.0	1315.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25VH6@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	pflB	-	2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
HALNLLBL_01223	1256908.HMPREF0373_02731	1.02e-137	394.0	COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,247NA@186801|Clostridia,25VM2@186806|Eubacteriaceae	186801|Clostridia	C	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
HALNLLBL_01225	1408437.JNJN01000019_gene26	5.15e-111	334.0	COG1086@1|root,COG1086@2|Bacteria,1U3RH@1239|Firmicutes,24K9I@186801|Clostridia	186801|Clostridia	GM	methyltransferase FkbM family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
HALNLLBL_01226	428125.CLOLEP_02036	5.95e-150	440.0	COG2607@1|root,COG2607@2|Bacteria,1TQDJ@1239|Firmicutes,2483S@186801|Clostridia,3WH9K@541000|Ruminococcaceae	186801|Clostridia	S	ATPase (AAA superfamily)	-	-	-	ko:K06923	-	-	-	-	ko00000	-	-	-	DUF815
HALNLLBL_01227	1430331.EP10_02930	3.59e-07	60.8	COG0791@1|root,COG3409@1|root,COG0791@2|Bacteria,COG3409@2|Bacteria,1TT2K@1239|Firmicutes,4ISYS@91061|Bacilli,1WF59@129337|Geobacillus	91061|Bacilli	M	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,PG_binding_1
HALNLLBL_01228	1105031.HMPREF1141_0377	4.02e-100	301.0	COG0122@1|root,COG0122@2|Bacteria,1TQAF@1239|Firmicutes,2495X@186801|Clostridia,36DTH@31979|Clostridiaceae	186801|Clostridia	L	8-oxoguanine DNA glycosylase	alkA	-	4.2.99.18	ko:K03660	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD,OGG_N
HALNLLBL_01229	428125.CLOLEP_01608	1.18e-76	239.0	28P0Q@1|root,2ZBX8@2|Bacteria,1V22P@1239|Firmicutes,248XV@186801|Clostridia,3WJK7@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01232	1160721.RBI_II00300	3.08e-308	853.0	COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,247P1@186801|Clostridia,3WH8S@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs1	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
HALNLLBL_01235	1121334.KB911069_gene1487	1.28e-88	266.0	COG1394@1|root,COG1394@2|Bacteria,1TQ4P@1239|Firmicutes,24Z7J@186801|Clostridia,3WH3C@541000|Ruminococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpD	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
HALNLLBL_01236	1120746.CCNL01000013_gene1968	8.62e-278	766.0	COG1156@1|root,COG1156@2|Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	atpB	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
HALNLLBL_01237	428125.CLOLEP_03321	0.0	935.0	COG1155@1|root,COG1155@2|Bacteria,1TPGS@1239|Firmicutes,24882@186801|Clostridia,3WGBK@541000|Ruminococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit	ntpA	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
HALNLLBL_01239	428125.CLOLEP_03319	3.26e-50	160.0	COG1436@1|root,COG1436@2|Bacteria,1VEN1@1239|Firmicutes,24K2E@186801|Clostridia,3WJWV@541000|Ruminococcaceae	186801|Clostridia	C	Archaeal vacuolar-type H -ATPase subunit F	-	-	-	ko:K02122	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_F
HALNLLBL_01240	428125.CLOLEP_03318	2.7e-26	103.0	COG0636@1|root,COG0636@2|Bacteria,1VF4U@1239|Firmicutes,25CR4@186801|Clostridia,3WJIE@541000|Ruminococcaceae	186801|Clostridia	C	ATP synthase subunit C	ntpK	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
HALNLLBL_01241	428125.CLOLEP_03317	4.9e-203	591.0	COG1269@1|root,COG1269@2|Bacteria,1TPTE@1239|Firmicutes,249YV@186801|Clostridia,3WHFQ@541000|Ruminococcaceae	186801|Clostridia	C	Belongs to the V-ATPase 116 kDa subunit family	ntpI	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
HALNLLBL_01242	1120746.CCNL01000013_gene1962	9.03e-83	262.0	COG1527@1|root,COG1527@2|Bacteria	2|Bacteria	C	subunit (C	ntpC	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_AC39
HALNLLBL_01244	1120746.CCNL01000013_gene1960	2.82e-256	711.0	COG2848@1|root,COG2848@2|Bacteria,2NPVH@2323|unclassified Bacteria	2|Bacteria	S	Uncharacterised ACR (DUF711)	-	-	-	ko:K09157	-	-	-	-	ko00000	-	-	-	DUF711
HALNLLBL_01245	428125.CLOLEP_03312	2.19e-33	117.0	COG3830@1|root,COG3830@2|Bacteria,1VENW@1239|Firmicutes,24QNV@186801|Clostridia,3WJVR@541000|Ruminococcaceae	186801|Clostridia	T	Belongs to the UPF0237 family	-	-	-	ko:K07166	-	-	-	-	ko00000	-	-	-	ACT_6
HALNLLBL_01246	1105031.HMPREF1141_2653	3.57e-65	211.0	COG1387@1|root,COG1387@2|Bacteria,1TRKS@1239|Firmicutes,249TM@186801|Clostridia,36FRF@31979|Clostridiaceae	186801|Clostridia	E	Histidinol phosphate phosphatase, HisJ family	-	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
HALNLLBL_01247	663278.Ethha_2193	1.18e-129	377.0	COG1210@1|root,COG1210@2|Bacteria,1TQ24@1239|Firmicutes,25E5A@186801|Clostridia,3WH3P@541000|Ruminococcaceae	186801|Clostridia	M	UTP-glucose-1-phosphate uridylyltransferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
HALNLLBL_01248	1121334.KB911069_gene1620	5.32e-53	186.0	2E0TS@1|root,32WBE@2|Bacteria,1VBFI@1239|Firmicutes,24PTN@186801|Clostridia,3WIIS@541000|Ruminococcaceae	186801|Clostridia	S	Prokaryotic RING finger family 1	-	-	-	-	-	-	-	-	-	-	-	-	DUF2628,Prok-RING_1
HALNLLBL_01249	428125.CLOLEP_00523	1.63e-194	548.0	COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,247KU@186801|Clostridia,3WG91@541000|Ruminococcaceae	186801|Clostridia	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
HALNLLBL_01250	428125.CLOLEP_00764	1.01e-206	581.0	COG3635@1|root,COG3635@2|Bacteria,1TQ5S@1239|Firmicutes,248U6@186801|Clostridia,3WH2J@541000|Ruminococcaceae	186801|Clostridia	G	phosphoglycerate mutase	-	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
HALNLLBL_01251	877411.JMMA01000002_gene1279	8.96e-33	115.0	2E3FD@1|root,32YE7@2|Bacteria,1VEE4@1239|Firmicutes,24QJ7@186801|Clostridia,3WKHY@541000|Ruminococcaceae	186801|Clostridia	S	TSCPD domain	-	-	-	-	-	-	-	-	-	-	-	-	TSCPD
HALNLLBL_01252	428125.CLOLEP_00529	2.62e-76	246.0	COG3935@1|root,COG3935@2|Bacteria,1TPR5@1239|Firmicutes,248E7@186801|Clostridia,3WJJV@541000|Ruminococcaceae	186801|Clostridia	L	DnaD domain protein	dnaD	-	-	-	-	-	-	-	-	-	-	-	DnaB_2
HALNLLBL_01253	428125.CLOLEP_00528	1.32e-86	270.0	COG1484@1|root,COG1484@2|Bacteria,1TPKM@1239|Firmicutes,2483D@186801|Clostridia,3WJBS@541000|Ruminococcaceae	186801|Clostridia	L	DNA replication protein	dnaC	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
HALNLLBL_01257	428125.CLOLEP_01918	2.58e-312	877.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia,3WGKX@541000|Ruminococcaceae	186801|Clostridia	L	ATP-dependent DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
HALNLLBL_01258	545697.HMPREF0216_02333	4.07e-56	197.0	COG1680@1|root,COG1680@2|Bacteria,1TRR5@1239|Firmicutes,249KP@186801|Clostridia,36H4V@31979|Clostridiaceae	186801|Clostridia	V	beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase,Cu_amine_oxidN1,DUF3471
HALNLLBL_01259	428125.CLOLEP_01917	7.34e-70	224.0	28J28@1|root,2Z8YU@2|Bacteria,1UYKD@1239|Firmicutes,24GNR@186801|Clostridia,3WHPZ@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01260	1120746.CCNL01000014_gene2193	3.31e-111	342.0	COG1167@1|root,COG1167@2|Bacteria	2|Bacteria	K	transaminase activity	gabR	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
HALNLLBL_01261	428125.CLOLEP_02021	1.34e-217	615.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,248GS@186801|Clostridia,3WG85@541000|Ruminococcaceae	186801|Clostridia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iHN637.CLJU_RS20420	Mur_ligase_C,Mur_ligase_M
HALNLLBL_01262	428125.CLOLEP_02022	5.72e-94	290.0	COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,24BAN@186801|Clostridia,3WG8E@541000|Ruminococcaceae	186801|Clostridia	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
HALNLLBL_01263	1120746.CCNL01000017_gene3115	3.2e-116	347.0	COG1363@1|root,COG1363@2|Bacteria	2|Bacteria	G	aminopeptidase activity	cel	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Peptidase_M42
HALNLLBL_01265	428125.CLOLEP_02025	1.92e-205	579.0	COG4100@1|root,COG4100@2|Bacteria,1TQ88@1239|Firmicutes,247Y4@186801|Clostridia,3WGF6@541000|Ruminococcaceae	186801|Clostridia	P	Cystathionine beta-lyase family protein involved in aluminum resistance	ynbB	-	-	-	-	-	-	-	-	-	-	-	Met_gamma_lyase
HALNLLBL_01266	1120746.CCNL01000017_gene3202	8.12e-65	201.0	COG0590@1|root,COG0590@2|Bacteria,2NPM7@2323|unclassified Bacteria	2|Bacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.1,3.5.4.33	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922,R10223	RC00074,RC00477,RC00514,RC00809	ko00000,ko00001,ko01000,ko03016	-	-	-	MafB19-deam
HALNLLBL_01267	428125.CLOLEP_00048	1.61e-22	105.0	COG1266@1|root,COG1266@2|Bacteria,1VKW2@1239|Firmicutes,24QJG@186801|Clostridia,3WM89@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
HALNLLBL_01268	877411.JMMA01000002_gene2598	1.34e-155	439.0	COG1211@1|root,COG1211@2|Bacteria,1TS1B@1239|Firmicutes,2484P@186801|Clostridia,3WJ9I@541000|Ruminococcaceae	186801|Clostridia	I	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
HALNLLBL_01269	877411.JMMA01000002_gene2599	8.67e-155	446.0	COG0451@1|root,COG0451@2|Bacteria,1TS59@1239|Firmicutes,247JP@186801|Clostridia,3WJ79@541000|Ruminococcaceae	186801|Clostridia	GM	epimerase dehydratase	-	-	4.1.1.35,4.2.1.46	ko:K01710,ko:K08678	ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00793	R01384,R06513	RC00402,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
HALNLLBL_01270	246199.CUS_7277	1.34e-78	264.0	COG3475@1|root,COG3475@2|Bacteria,1VBSV@1239|Firmicutes,24C5H@186801|Clostridia,3WKAI@541000|Ruminococcaceae	186801|Clostridia	M	LicD family	licD	-	-	ko:K07271	-	-	-	-	ko00000,ko01000	-	-	-	LicD
HALNLLBL_01271	428125.CLOLEP_03303	2.09e-76	232.0	COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes,24FUS@186801|Clostridia,3WIZW@541000|Ruminococcaceae	186801|Clostridia	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
HALNLLBL_01272	428125.CLOLEP_03302	5.89e-34	117.0	COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,24QJD@186801|Clostridia,3WKKQ@541000|Ruminococcaceae	186801|Clostridia	J	Ribosomal protein L35	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
HALNLLBL_01273	428125.CLOLEP_03301	2.22e-66	202.0	COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,24JBJ@186801|Clostridia,3WIYY@541000|Ruminococcaceae	186801|Clostridia	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
HALNLLBL_01274	428125.CLOLEP_03300	5.94e-81	251.0	COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,248DV@186801|Clostridia,3WIQ9@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
HALNLLBL_01275	1105031.HMPREF1141_2666	1.23e-71	238.0	COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,24AS2@186801|Clostridia,36EJZ@31979|Clostridiaceae	186801|Clostridia	LU	DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
HALNLLBL_01276	428125.CLOLEP_03298	0.0	935.0	COG0550@1|root,COG0550@2|Bacteria,1TPUS@1239|Firmicutes,248MG@186801|Clostridia,3WGDZ@541000|Ruminococcaceae	186801|Clostridia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
HALNLLBL_01277	1120746.CCNL01000012_gene1942	3.7e-211	595.0	COG1206@1|root,COG1206@2|Bacteria,2NS4B@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
HALNLLBL_01278	428125.CLOLEP_03296	2.96e-143	414.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia,3WGC6@541000|Ruminococcaceae	186801|Clostridia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
HALNLLBL_01279	428125.CLOLEP_03295	2.82e-108	318.0	COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,249QD@186801|Clostridia,3WG7D@541000|Ruminococcaceae	186801|Clostridia	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
HALNLLBL_01280	1120746.CCNL01000012_gene1939	2.36e-96	295.0	COG1243@1|root,COG1243@2|Bacteria	2|Bacteria	BK	radical SAM domain protein	-	-	2.3.1.48	ko:K07739	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	Acetyltransf_1,Fer4_14,Radical_SAM,Radical_SAM_C
HALNLLBL_01281	1120746.CCNL01000012_gene1938	0.0	969.0	COG1196@1|root,COG1196@2|Bacteria,2NNYZ@2323|unclassified Bacteria	2|Bacteria	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
HALNLLBL_01282	428125.CLOLEP_03292	1.23e-157	449.0	COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,247JD@186801|Clostridia,3WGFT@541000|Ruminococcaceae	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
HALNLLBL_01283	1105031.HMPREF1141_2674	1.22e-78	240.0	COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,249GK@186801|Clostridia,36HYU@31979|Clostridiaceae	186801|Clostridia	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
HALNLLBL_01284	428125.CLOLEP_03289	7.19e-39	132.0	COG1534@1|root,COG1534@2|Bacteria,1VEGM@1239|Firmicutes,24QZB@186801|Clostridia,3WKIM@541000|Ruminococcaceae	186801|Clostridia	J	RNA-binding protein, YhbY family	yhbY	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
HALNLLBL_01285	1105031.HMPREF1141_2676	4.07e-50	168.0	COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,24JFM@186801|Clostridia,36I7Z@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
HALNLLBL_01286	428125.CLOLEP_03287	9.65e-67	209.0	COG1713@1|root,COG1713@2|Bacteria,1V6Y1@1239|Firmicutes,24HN2@186801|Clostridia,3WJZX@541000|Ruminococcaceae	186801|Clostridia	H	HD superfamily hydrolase involved in NAD metabolism	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like,HD
HALNLLBL_01287	428125.CLOLEP_03286	8.26e-44	145.0	COG0799@1|root,COG0799@2|Bacteria,1VA2Z@1239|Firmicutes,24MVA@186801|Clostridia,3WJVU@541000|Ruminococcaceae	186801|Clostridia	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
HALNLLBL_01288	1120746.CCNL01000012_gene1931	0.0	1355.0	COG0495@1|root,COG0495@2|Bacteria,2NNQH@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
HALNLLBL_01289	1105031.HMPREF1141_0762	5.27e-25	94.0	COG0828@1|root,COG0828@2|Bacteria,1VEHU@1239|Firmicutes,24QP9@186801|Clostridia,36MKD@31979|Clostridiaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
HALNLLBL_01290	1120746.CCNL01000011_gene1643	4.13e-75	227.0	COG0757@1|root,COG0757@2|Bacteria,2NPMW@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM0349	DHquinase_II
HALNLLBL_01291	428125.CLOLEP_03279	1.76e-98	303.0	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,247SG@186801|Clostridia,3WGZP@541000|Ruminococcaceae	186801|Clostridia	E	Xaa-Pro aminopeptidase	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
HALNLLBL_01292	1105031.HMPREF1141_0768	6.76e-119	341.0	COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,249DV@186801|Clostridia,36DS4@31979|Clostridiaceae	186801|Clostridia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
HALNLLBL_01293	1105031.HMPREF1141_0769	8.29e-21	90.1	2E3FE@1|root,32YE8@2|Bacteria,1VFR0@1239|Firmicutes,24MNV@186801|Clostridia,36W39@31979|Clostridiaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01294	537013.CLOSTMETH_02581	1.99e-23	101.0	2B51H@1|root,31XUS@2|Bacteria,1V6KA@1239|Firmicutes,24JQP@186801|Clostridia,3WKHP@541000|Ruminococcaceae	186801|Clostridia	S	sporulation protein YunB	yunB	-	-	-	-	-	-	-	-	-	-	-	Spore_YunB
HALNLLBL_01295	1120746.CCNL01000011_gene1865	9.93e-233	652.0	COG0621@1|root,COG0621@2|Bacteria,2NNUN@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
HALNLLBL_01296	1121334.KB911070_gene1301	3.09e-28	107.0	COG3679@1|root,COG3679@2|Bacteria,1VDFJ@1239|Firmicutes,24MY6@186801|Clostridia,3WJJP@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the UPF0342 family	-	-	-	-	-	-	-	-	-	-	-	-	Com_YlbF
HALNLLBL_01297	428125.CLOLEP_01950	0.0	1104.0	COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,248GI@186801|Clostridia,3WGM4@541000|Ruminococcaceae	186801|Clostridia	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
HALNLLBL_01298	1121334.KB911070_gene1299	8.39e-215	625.0	COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,24902@186801|Clostridia,3WHC5@541000|Ruminococcaceae	186801|Clostridia	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
HALNLLBL_01299	1120746.CCNL01000011_gene1860	1.18e-110	330.0	COG0324@1|root,COG0324@2|Bacteria,2NP6D@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
HALNLLBL_01300	428125.CLOLEP_01954	4.72e-93	294.0	COG0845@1|root,COG0845@2|Bacteria,1VE61@1239|Firmicutes,24P4D@186801|Clostridia,3WRFY@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01301	428125.CLOLEP_01955	2.39e-92	278.0	COG0325@1|root,COG0325@2|Bacteria,1TRDN@1239|Firmicutes,248R6@186801|Clostridia,3WGKD@541000|Ruminococcaceae	186801|Clostridia	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	ylmE	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
HALNLLBL_01313	1408436.JHXY01000010_gene886	2.92e-67	207.0	COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,24HDD@186801|Clostridia,25WT8@186806|Eubacteriaceae	186801|Clostridia	C	SUF system FeS assembly protein, NifU family	iscU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
HALNLLBL_01314	742733.HMPREF9469_05810	1.54e-199	563.0	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,249CS@186801|Clostridia,21Z26@1506553|Lachnoclostridium	186801|Clostridia	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
HALNLLBL_01315	742733.HMPREF9469_05809	1.77e-93	291.0	COG0719@1|root,COG0719@2|Bacteria,1TRQJ@1239|Firmicutes,24ANC@186801|Clostridia,220RB@1506553|Lachnoclostridium	186801|Clostridia	O	Uncharacterized protein family (UPF0051)	sufD	-	-	ko:K07033,ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
HALNLLBL_01316	411489.CLOL250_02466	3.37e-295	810.0	COG0719@1|root,COG0719@2|Bacteria,1TQ21@1239|Firmicutes,249IU@186801|Clostridia,36G21@31979|Clostridiaceae	186801|Clostridia	O	FeS assembly protein SufB	sufB	-	-	ko:K07033,ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
HALNLLBL_01317	411474.COPEUT_00642	1.72e-126	365.0	COG0396@1|root,COG0396@2|Bacteria,1TQ98@1239|Firmicutes,2489I@186801|Clostridia	186801|Clostridia	O	FeS assembly ATPase SufC	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
HALNLLBL_01318	742733.HMPREF9469_05806	1.13e-54	174.0	COG1959@1|root,COG1959@2|Bacteria,1V3QB@1239|Firmicutes,24JIV@186801|Clostridia,2208Z@1506553|Lachnoclostridium	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
HALNLLBL_01319	1105031.HMPREF1141_0293	1.69e-42	148.0	COG3432@1|root,COG3432@2|Bacteria,1VDQ8@1239|Firmicutes,24R9Q@186801|Clostridia,36SG2@31979|Clostridiaceae	186801|Clostridia	K	Domain of unknown function (DUF4364)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4364
HALNLLBL_01320	1105031.HMPREF1141_0300	3.57e-17	76.3	2FBQ5@1|root,343V3@2|Bacteria,1W614@1239|Firmicutes,251H7@186801|Clostridia	186801|Clostridia	S	SigmaK-factor processing regulatory protein BofA	-	-	-	-	-	-	-	-	-	-	-	-	BofA
HALNLLBL_01321	1105031.HMPREF1141_0303	5.5e-22	88.2	COG1314@1|root,COG1314@2|Bacteria	2|Bacteria	U	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	secG	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
HALNLLBL_01322	428125.CLOLEP_02604	0.0	1088.0	COG0188@1|root,COG0188@2|Bacteria,1TPPU@1239|Firmicutes,24CU3@186801|Clostridia,3WG8X@541000|Ruminococcaceae	186801|Clostridia	L	PFAM DNA gyrase topoisomerase IV, subunit A	-	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
HALNLLBL_01323	428125.CLOLEP_02601	0.0	1038.0	COG0187@1|root,COG0187@2|Bacteria,1TQ6U@1239|Firmicutes,249NI@186801|Clostridia,3WH8Y@541000|Ruminococcaceae	186801|Clostridia	L	DNA topoisomerase	-	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
HALNLLBL_01324	428125.CLOLEP_03191	0.0	1039.0	COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,247P7@186801|Clostridia,3WGH5@541000|Ruminococcaceae	186801|Clostridia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
HALNLLBL_01325	428125.CLOLEP_03081	3.49e-61	199.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,2498Z@186801|Clostridia,3WJ3Y@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	HHH,RadC
HALNLLBL_01326	476272.RUMHYD_02454	1.69e-142	404.0	COG0461@1|root,COG0461@2|Bacteria,1TREW@1239|Firmicutes,248WM@186801|Clostridia,3XYW9@572511|Blautia	186801|Clostridia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
HALNLLBL_01328	428125.CLOLEP_03536	2.71e-178	510.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,24855@186801|Clostridia,3WGV5@541000|Ruminococcaceae	186801|Clostridia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
HALNLLBL_01329	428125.CLOLEP_02108	1.25e-32	114.0	2E5HW@1|root,33098@2|Bacteria,1VFFD@1239|Firmicutes,24QMD@186801|Clostridia,3WM6E@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01330	1321778.HMPREF1982_00514	7.31e-141	405.0	COG1533@1|root,COG1533@2|Bacteria,1TSS2@1239|Firmicutes,248SB@186801|Clostridia,268M6@186813|unclassified Clostridiales	186801|Clostridia	L	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
HALNLLBL_01333	1304880.JAGB01000002_gene1652	1.57e-07	60.1	COG5578@1|root,COG5578@2|Bacteria,1V3G3@1239|Firmicutes,24H3P@186801|Clostridia	186801|Clostridia	S	Protein of unknown function, DUF624	-	-	-	-	-	-	-	-	-	-	-	-	DUF624
HALNLLBL_01335	428125.CLOLEP_03121	1.2e-87	268.0	COG0345@1|root,COG0345@2|Bacteria,1TP1E@1239|Firmicutes,247SR@186801|Clostridia,3WGT7@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
HALNLLBL_01336	1139996.OMQ_02181	1.85e-10	72.8	COG5492@1|root,COG5492@2|Bacteria,1TT7E@1239|Firmicutes,4HCCG@91061|Bacilli	91061|Bacilli	N	Domain of unknown function (DUF5057)	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF5057
HALNLLBL_01337	290402.Cbei_1413	4.98e-10	63.2	2DQ8Z@1|root,335CG@2|Bacteria,1V9R5@1239|Firmicutes,24JTW@186801|Clostridia,36KXI@31979|Clostridiaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01338	428125.CLOLEP_03188	6.28e-60	193.0	COG0484@1|root,COG0484@2|Bacteria,1V1GK@1239|Firmicutes,2494E@186801|Clostridia,3WITE@541000|Ruminococcaceae	186801|Clostridia	O	DnaJ domain protein	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,TPR_2
HALNLLBL_01339	1105031.HMPREF1141_3135	2.92e-77	244.0	2CC4I@1|root,2Z8PZ@2|Bacteria,1TQTT@1239|Firmicutes,24AJ3@186801|Clostridia,36F6T@31979|Clostridiaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01340	706433.HMPREF9430_01413	2.15e-53	175.0	COG0560@1|root,COG0560@2|Bacteria,1V8Y8@1239|Firmicutes,3VQNW@526524|Erysipelotrichia	526524|Erysipelotrichia	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
HALNLLBL_01341	428125.CLOLEP_02105	6.45e-141	407.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,3WGCR@541000|Ruminococcaceae	186801|Clostridia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
HALNLLBL_01342	428125.CLOLEP_02104	1.91e-145	413.0	COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,3WGT4@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
HALNLLBL_01344	663278.Ethha_1626	5.42e-16	73.9	COG1873@1|root,COG1873@2|Bacteria,1VGWH@1239|Firmicutes,259AU@186801|Clostridia,3WKPN@541000|Ruminococcaceae	186801|Clostridia	S	sporulation protein, YlmC YmxH family	-	-	-	-	-	-	-	-	-	-	-	-	PRC
HALNLLBL_01345	318464.IO99_15925	3.92e-97	294.0	COG1307@1|root,COG1307@2|Bacteria,1TQDI@1239|Firmicutes,24ADT@186801|Clostridia,36EZJ@31979|Clostridiaceae	186801|Clostridia	S	DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
HALNLLBL_01346	1120746.CCNL01000011_gene1798	7.42e-39	144.0	2APHB@1|root,31EKA@2|Bacteria,2NRSM@2323|unclassified Bacteria	2|Bacteria	S	Sporulation factor SpoIIGA	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_U4
HALNLLBL_01347	428125.CLOLEP_02097	1.83e-109	321.0	COG1191@1|root,COG1191@2|Bacteria,1TP3T@1239|Firmicutes,24A4T@186801|Clostridia,3WGM5@541000|Ruminococcaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigE	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
HALNLLBL_01349	1120746.CCNL01000010_gene1198	1.01e-53	182.0	COG0668@1|root,COG0668@2|Bacteria,2NP91@2323|unclassified Bacteria	2|Bacteria	M	Mechanosensitive ion channel	mscS	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022607,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0055082,GO:0055085,GO:0065003,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
HALNLLBL_01351	428125.CLOLEP_00557	1.7e-164	469.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,248PB@186801|Clostridia,3WH67@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
HALNLLBL_01352	1280673.AUJJ01000011_gene1980	4.93e-146	421.0	COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,248Q5@186801|Clostridia,4BYPC@830|Butyrivibrio	186801|Clostridia	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HALNLLBL_01353	386043.lwe1058	2.91e-25	118.0	COG1807@1|root,COG1807@2|Bacteria,1UYWB@1239|Firmicutes,4HE3A@91061|Bacilli,26JE3@186820|Listeriaceae	91061|Bacilli	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
HALNLLBL_01354	500632.CLONEX_00165	4.89e-99	322.0	COG3274@1|root,COG3274@2|Bacteria,1UYCP@1239|Firmicutes,24FH8@186801|Clostridia	186801|Clostridia	S	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
HALNLLBL_01355	428125.CLOLEP_00237	3.48e-252	710.0	COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,2481Y@186801|Clostridia,3WGEY@541000|Ruminococcaceae	186801|Clostridia	G	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain	pgcA	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
HALNLLBL_01356	622312.ROSEINA2194_04006	1.61e-80	244.0	COG1247@1|root,COG1247@2|Bacteria,1V6X5@1239|Firmicutes,24IB5@186801|Clostridia	186801|Clostridia	M	Acetyltransferase GNAT family	pat	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
HALNLLBL_01359	641112.ACOK01000001_gene3581	3.12e-279	775.0	COG0519@1|root,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,2487F@186801|Clostridia,3WGXK@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
HALNLLBL_01360	428125.CLOLEP_03227	6.9e-258	712.0	COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,247RN@186801|Clostridia,3WGUF@541000|Ruminococcaceae	186801|Clostridia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
HALNLLBL_01361	428125.CLOLEP_03228	2.3e-279	771.0	COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia,3WG9P@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
HALNLLBL_01362	428125.CLOLEP_03229	2.21e-248	694.0	COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,247RF@186801|Clostridia,3WH6T@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
HALNLLBL_01363	1121334.KB911072_gene2558	2.84e-133	381.0	COG0152@1|root,COG0152@2|Bacteria,1TP11@1239|Firmicutes,2483I@186801|Clostridia,3WGZE@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the SAICAR synthetase family	purC	-	4.3.2.2,6.3.2.6	ko:K01756,ko:K01923	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559,R04591	RC00064,RC00162,RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
HALNLLBL_01364	552398.HMPREF0866_02083	1.17e-06	57.4	COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,247RF@186801|Clostridia,3WGHD@541000|Ruminococcaceae	186801|Clostridia	F	Glutamine phosphoribosylpyrophosphate amidotransferase	purF_1	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7,Pribosyltran
HALNLLBL_01366	428125.CLOLEP_01062	5.44e-211	594.0	COG4198@1|root,COG4198@2|Bacteria,1TQSW@1239|Firmicutes,249E4@186801|Clostridia,3WK6T@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
HALNLLBL_01367	858215.Thexy_0401	1.3e-38	135.0	COG3467@1|root,COG3467@2|Bacteria,1V7MR@1239|Firmicutes,25B09@186801|Clostridia,42I93@68295|Thermoanaerobacterales	186801|Clostridia	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
HALNLLBL_01368	1235800.C819_00062	1.91e-42	157.0	COG0252@1|root,COG0252@2|Bacteria,1TPP9@1239|Firmicutes,248F3@186801|Clostridia,27IMZ@186928|unclassified Lachnospiraceae	186801|Clostridia	EJ	Asparaginase	ansA	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
HALNLLBL_01370	397287.C807_03443	4.4e-158	459.0	COG0475@1|root,COG0475@2|Bacteria,1TS32@1239|Firmicutes,247XW@186801|Clostridia,27J6N@186928|unclassified Lachnospiraceae	186801|Clostridia	P	Sodium/hydrogen exchanger family	napA	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
HALNLLBL_01371	1226325.HMPREF1548_04369	4.28e-42	146.0	COG1309@1|root,COG1309@2|Bacteria,1V7J5@1239|Firmicutes,24JZZ@186801|Clostridia,36KF2@31979|Clostridiaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HALNLLBL_01372	428125.CLOLEP_00512	1.43e-300	845.0	COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,247WH@186801|Clostridia,3WGDM@541000|Ruminococcaceae	186801|Clostridia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
HALNLLBL_01373	1232453.BAIF02000102_gene3673	3.08e-34	144.0	2AHKI@1|root,317YB@2|Bacteria,1V965@1239|Firmicutes,24MIW@186801|Clostridia,26BP7@186813|unclassified Clostridiales	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
HALNLLBL_01374	545694.TREPR_3601	1.13e-17	89.4	COG1752@1|root,COG1752@2|Bacteria,2J6JW@203691|Spirochaetes	203691|Spirochaetes	M	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Bac_surface_Ag,Patatin
HALNLLBL_01375	698758.AXY_19270	3.26e-42	149.0	28JM5@1|root,2Z9DQ@2|Bacteria,1TS2D@1239|Firmicutes,4HRPU@91061|Bacilli	91061|Bacilli	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01376	411483.FAEPRAA2165_01602	4.4e-25	94.4	COG4481@1|root,COG4481@2|Bacteria,1VEQ7@1239|Firmicutes,24QKA@186801|Clostridia,3WKJ4@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF951
HALNLLBL_01377	428125.CLOLEP_03918	3.23e-177	503.0	COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,248CN@186801|Clostridia,3WGA4@541000|Ruminococcaceae	186801|Clostridia	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
HALNLLBL_01378	428125.CLOLEP_03920	2.03e-134	393.0	COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,248HS@186801|Clostridia,3WGIY@541000|Ruminococcaceae	186801|Clostridia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	sua	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
HALNLLBL_01379	1341157.RF007C_09105	9.01e-53	175.0	COG0237@1|root,COG0237@2|Bacteria,1V6FS@1239|Firmicutes,24GFQ@186801|Clostridia,3WJC8@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
HALNLLBL_01380	537013.CLOSTMETH_03355	1.69e-36	133.0	COG0741@1|root,COG0741@2|Bacteria,1V6K4@1239|Firmicutes,24JB5@186801|Clostridia,3WKAS@541000|Ruminococcaceae	186801|Clostridia	M	Transglycosylase SLT domain	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
HALNLLBL_01381	428125.CLOLEP_03923	6.56e-229	643.0	COG1362@1|root,COG1362@2|Bacteria,1TP6G@1239|Firmicutes,2486Y@186801|Clostridia,3WHAH@541000|Ruminococcaceae	186801|Clostridia	E	M18 family aminopeptidase	apeA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M18
HALNLLBL_01383	1203606.HMPREF1526_02883	6.91e-36	125.0	2CCSR@1|root,32RWC@2|Bacteria,1VHG8@1239|Firmicutes,24N36@186801|Clostridia,36K2K@31979|Clostridiaceae	186801|Clostridia	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
HALNLLBL_01384	552396.HMPREF0863_01358	1.31e-28	126.0	COG3942@1|root,COG5492@1|root,COG3942@2|Bacteria,COG5492@2|Bacteria,1VFAV@1239|Firmicutes	1239|Firmicutes	M	CHAP domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CHAP,CW_binding_1,GBS_Bsp-like,RicinB_lectin_2
HALNLLBL_01385	796940.HMPREF9628_02137	6.19e-60	209.0	COG3290@1|root,COG3290@2|Bacteria,1V0KZ@1239|Firmicutes,25BG0@186801|Clostridia	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
HALNLLBL_01386	1458462.JNLK01000001_gene2795	1.19e-42	152.0	COG3279@1|root,COG3279@2|Bacteria,1VA5A@1239|Firmicutes,24DB9@186801|Clostridia,27TB9@186928|unclassified Lachnospiraceae	186801|Clostridia	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
HALNLLBL_01388	1410617.JHXH01000013_gene6	6.32e-111	331.0	COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,248UR@186801|Clostridia,3WG9C@541000|Ruminococcaceae	186801|Clostridia	CH	D-isomer specific 2-hydroxyacid dehydrogenase	hprA	-	1.1.1.29,1.1.1.399,1.1.1.95	ko:K00018,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00020,M00346	R00717,R01388,R01513	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
HALNLLBL_01389	471875.RUMLAC_01710	6.17e-56	186.0	COG0546@1|root,COG0546@2|Bacteria,1V3MH@1239|Firmicutes,25F06@186801|Clostridia	186801|Clostridia	S	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
HALNLLBL_01390	428125.CLOLEP_01772	0.0	1846.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1TPAS@1239|Firmicutes,247W2@186801|Clostridia,3WGRN@541000|Ruminococcaceae	186801|Clostridia	F	phosphoribosylformylglycinamidine synthase	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
HALNLLBL_01391	428125.CLOLEP_03916	4.65e-100	305.0	COG0340@1|root,COG0340@2|Bacteria,1TQCU@1239|Firmicutes,248CK@186801|Clostridia,3WHDB@541000|Ruminococcaceae	186801|Clostridia	HK	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
HALNLLBL_01392	622312.ROSEINA2194_00831	2.12e-47	161.0	COG4684@1|root,COG4684@2|Bacteria,1V2ZW@1239|Firmicutes	1239|Firmicutes	S	ECF transporter, substrate-specific component	-	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
HALNLLBL_01393	428125.CLOLEP_02571	9.21e-84	258.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,248PX@186801|Clostridia,3WHZV@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
HALNLLBL_01394	1120746.CCNL01000008_gene578	2.45e-137	395.0	COG3959@1|root,COG3959@2|Bacteria,2NP12@2323|unclassified Bacteria	2|Bacteria	G	Transketolase, thiamine diphosphate binding domain	tktA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
HALNLLBL_01395	1120746.CCNL01000008_gene579	6.67e-158	450.0	COG3958@1|root,COG3958@2|Bacteria,2NQFH@2323|unclassified Bacteria	2|Bacteria	G	Transketolase, pyrimidine binding domain	tklB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
HALNLLBL_01397	1120746.CCNL01000017_gene3230	5.77e-209	583.0	COG0012@1|root,COG0012@2|Bacteria,2NNNF@2323|unclassified Bacteria	2|Bacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
HALNLLBL_01398	633697.EubceDRAFT1_1583	2.91e-23	94.7	COG5496@1|root,COG5496@2|Bacteria,1VAZJ@1239|Firmicutes,24MWR@186801|Clostridia,25WV6@186806|Eubacteriaceae	186801|Clostridia	S	THIoesterase	-	-	3.1.2.29	ko:K18700	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
HALNLLBL_01399	742765.HMPREF9457_00274	1.83e-40	144.0	COG0546@1|root,COG0546@2|Bacteria,1V1FQ@1239|Firmicutes,24G1U@186801|Clostridia,27VI1@189330|Dorea	186801|Clostridia	S	HAD-hyrolase-like	nt5e	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
HALNLLBL_01401	428125.CLOLEP_01618	1.6e-74	234.0	COG1187@1|root,COG1187@2|Bacteria,1TQZ2@1239|Firmicutes,248HC@186801|Clostridia,3WHTI@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rsuA	-	5.4.99.19	ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
HALNLLBL_01402	1120746.CCNL01000017_gene3154	3.79e-205	574.0	COG3842@1|root,COG3842@2|Bacteria,2NNU0@2323|unclassified Bacteria	2|Bacteria	E	ATPases associated with a variety of cellular activities	msmX	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
HALNLLBL_01403	428125.CLOLEP_01620	6.44e-216	601.0	COG3835@1|root,COG3835@2|Bacteria,1TQWD@1239|Firmicutes,24ZMW@186801|Clostridia,3WHDV@541000|Ruminococcaceae	186801|Clostridia	KT	Psort location Cytoplasmic, score	-	-	-	ko:K02647	-	-	-	-	ko00000,ko03000	-	-	-	Diacid_rec,HTH_30
HALNLLBL_01404	428125.CLOLEP_01621	4.49e-103	305.0	COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,248HW@186801|Clostridia,3WGK4@541000|Ruminococcaceae	186801|Clostridia	D	cell division ATP-binding protein FtsE	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
HALNLLBL_01405	1120746.CCNL01000017_gene3151	3.31e-88	272.0	COG2177@1|root,COG2177@2|Bacteria	2|Bacteria	D	cell division	ftsX	GO:0000910,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008356,GO:0009274,GO:0009276,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0016020,GO:0016021,GO:0016043,GO:0019221,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0023052,GO:0030312,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0032153,GO:0032506,GO:0034097,GO:0040007,GO:0042173,GO:0042221,GO:0043937,GO:0043938,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0051716,GO:0065007,GO:0070098,GO:0070297,GO:0070887,GO:0071310,GO:0071345,GO:0071840,GO:0071944,GO:0090529,GO:1902531	-	ko:K09811,ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
HALNLLBL_01406	428125.CLOLEP_01623	1.88e-51	187.0	COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,248ZG@186801|Clostridia,3WGCB@541000|Ruminococcaceae	186801|Clostridia	D	Peptidase, M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
HALNLLBL_01408	428125.CLOLEP_01626	1.01e-52	171.0	COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,24HP9@186801|Clostridia,3WIJW@541000|Ruminococcaceae	186801|Clostridia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
HALNLLBL_01409	665950.HMPREF1025_02289	0.0	989.0	COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia,27I57@186928|unclassified Lachnospiraceae	186801|Clostridia	J	tRNA synthetases class II (D, K and N)	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon,tRNA_bind
HALNLLBL_01410	511680.BUTYVIB_02251	2.6e-69	211.0	2C5R4@1|root,2ZC1N@2|Bacteria,1V292@1239|Firmicutes,25CQM@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
HALNLLBL_01411	511680.BUTYVIB_02250	3.45e-119	342.0	COG1595@1|root,COG1595@2|Bacteria,1UZ1M@1239|Firmicutes,24AUS@186801|Clostridia	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HALNLLBL_01412	511680.BUTYVIB_02249	3.07e-229	637.0	2E4RQ@1|root,32ZK7@2|Bacteria,1VI66@1239|Firmicutes,24TZR@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01413	483218.BACPEC_02561	1.04e-155	447.0	COG4974@1|root,COG4974@2|Bacteria,1TR57@1239|Firmicutes,24ACW@186801|Clostridia,26AN9@186813|unclassified Clostridiales	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
HALNLLBL_01414	573061.Clocel_4359	1.28e-36	147.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,36DTR@31979|Clostridiaceae	186801|Clostridia	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
HALNLLBL_01418	428125.CLOLEP_02245	7e-84	249.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,24HD6@186801|Clostridia,3WIZR@541000|Ruminococcaceae	186801|Clostridia	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
HALNLLBL_01419	1120746.CCNL01000010_gene1321	1.08e-104	306.0	COG0353@1|root,COG0353@2|Bacteria,2NP5N@2323|unclassified Bacteria	2|Bacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
HALNLLBL_01420	1121334.KB911072_gene2672	6.23e-50	161.0	COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,24MXH@186801|Clostridia,3WJW1@541000|Ruminococcaceae	186801|Clostridia	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
HALNLLBL_01421	1121334.KB911072_gene2671	2.1e-176	518.0	COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,247J7@186801|Clostridia,3WGA1@541000|Ruminococcaceae	186801|Clostridia	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
HALNLLBL_01422	483218.BACPEC_01832	2.25e-289	795.0	COG2509@1|root,COG2509@2|Bacteria,1TP9I@1239|Firmicutes,247QM@186801|Clostridia,2688C@186813|unclassified Clostridiales	186801|Clostridia	S	'oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	FAD_binding_2,HI0933_like,Pyr_redox_2,Thi4
HALNLLBL_01423	585394.RHOM_08570	4.45e-108	317.0	COG1207@1|root,COG1207@2|Bacteria	2|Bacteria	M	glucosamine-1-phosphate N-acetyltransferase activity	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep
HALNLLBL_01425	1216932.CM240_0432	2.79e-39	139.0	COG0671@1|root,COG0671@2|Bacteria,1VB7J@1239|Firmicutes,24JDD@186801|Clostridia,36JV0@31979|Clostridiaceae	186801|Clostridia	I	Membrane-associated phospholipid phosphatase	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
HALNLLBL_01426	428125.CLOLEP_01459	1.64e-188	536.0	COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,248IU@186801|Clostridia,3WH00@541000|Ruminococcaceae	186801|Clostridia	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
HALNLLBL_01427	1200567.JNKD01000075_gene1090	3.14e-87	262.0	COG0110@1|root,COG0110@2|Bacteria,1RA2T@1224|Proteobacteria,1S3ZZ@1236|Gammaproteobacteria,1Y4GY@135624|Aeromonadales	135624|Aeromonadales	S	Maltose acetyltransferase	-	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2,Mac
HALNLLBL_01429	1469948.JPNB01000001_gene558	1.18e-42	144.0	COG2153@1|root,COG2153@2|Bacteria,1VA2J@1239|Firmicutes,24R8H@186801|Clostridia,36I3D@31979|Clostridiaceae	186801|Clostridia	S	acetyltransferase, GNAT family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
HALNLLBL_01432	1476973.JMMB01000007_gene2253	6.52e-49	158.0	COG1917@1|root,COG1917@2|Bacteria,1VGJQ@1239|Firmicutes,25EGC@186801|Clostridia	186801|Clostridia	S	Cupin domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
HALNLLBL_01433	476272.RUMHYD_00395	4.01e-74	226.0	COG1247@1|root,COG1247@2|Bacteria,1V3XH@1239|Firmicutes,24HCN@186801|Clostridia,3Y0EN@572511|Blautia	186801|Clostridia	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HALNLLBL_01434	428125.CLOLEP_01532	4.06e-220	617.0	COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,248QF@186801|Clostridia,3WGI3@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
HALNLLBL_01435	1160721.RBI_I01660	9.08e-67	204.0	COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,24J8Y@186801|Clostridia,3WJG0@541000|Ruminococcaceae	186801|Clostridia	J	endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
HALNLLBL_01436	411473.RUMCAL_00117	1.89e-210	590.0	COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,248D5@186801|Clostridia,3WH1M@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PALP
HALNLLBL_01437	1121115.AXVN01000004_gene1967	2.23e-68	209.0	COG0716@1|root,COG0716@2|Bacteria,1V6D7@1239|Firmicutes,24J7W@186801|Clostridia,3Y024@572511|Blautia	186801|Clostridia	C	Flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1
HALNLLBL_01438	610130.Closa_0593	1.1e-75	231.0	2BYWB@1|root,32SGE@2|Bacteria,1V4H1@1239|Firmicutes,25CVU@186801|Clostridia,220BR@1506553|Lachnoclostridium	186801|Clostridia	S	Protein of unknown function (DUF3793)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3793
HALNLLBL_01439	610130.Closa_0591	4.29e-101	306.0	COG2207@1|root,COG2207@2|Bacteria,1TSFI@1239|Firmicutes,249B8@186801|Clostridia,22112@1506553|Lachnoclostridium	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
HALNLLBL_01440	742735.HMPREF9467_02854	5.51e-34	121.0	COG2608@1|root,COG2608@2|Bacteria,1VEMB@1239|Firmicutes,24REK@186801|Clostridia,220T7@1506553|Lachnoclostridium	186801|Clostridia	P	Heavy-metal-associated domain	-	-	-	-	-	-	-	-	-	-	-	-	HMA,P12
HALNLLBL_01441	411463.EUBVEN_01416	3.76e-274	780.0	COG0577@1|root,COG0577@2|Bacteria,1TPHU@1239|Firmicutes,247QW@186801|Clostridia,25VGB@186806|Eubacteriaceae	186801|Clostridia	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
HALNLLBL_01442	411463.EUBVEN_01417	2.86e-134	384.0	COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,248Z6@186801|Clostridia,25V4X@186806|Eubacteriaceae	186801|Clostridia	V	ABC-type antimicrobial peptide transport system, ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HALNLLBL_01444	1160721.RBI_I00823	0.0	1236.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,24885@186801|Clostridia,3WGIX@541000|Ruminococcaceae	186801|Clostridia	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
HALNLLBL_01445	877414.ATWA01000007_gene189	1.63e-39	131.0	COG1918@1|root,COG1918@2|Bacteria,1VEHC@1239|Firmicutes,24QKE@186801|Clostridia,269AQ@186813|unclassified Clostridiales	186801|Clostridia	P	FeoA	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
HALNLLBL_01446	588581.Cpap_3464	2.3e-31	110.0	COG1918@1|root,COG1918@2|Bacteria,1VEYA@1239|Firmicutes,24QKX@186801|Clostridia,3WKEV@541000|Ruminococcaceae	186801|Clostridia	P	FeoA	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
HALNLLBL_01447	411467.BACCAP_01257	2.5e-43	145.0	COG1321@1|root,COG1321@2|Bacteria,1V3IS@1239|Firmicutes,24MSE@186801|Clostridia,26931@186813|unclassified Clostridiales	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Fe_dep_repr_C,Fe_dep_repress
HALNLLBL_01448	1121289.JHVL01000064_gene299	1.09e-21	92.8	2ED9K@1|root,33761@2|Bacteria,1VEHV@1239|Firmicutes,24S9B@186801|Clostridia,36MUZ@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01449	1123075.AUDP01000030_gene1813	4.45e-26	103.0	COG3177@1|root,COG3177@2|Bacteria,1TZWX@1239|Firmicutes,247MZ@186801|Clostridia,3WHZR@541000|Ruminococcaceae	186801|Clostridia	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,HTH_17
HALNLLBL_01450	1120746.CCNL01000017_gene3231	0.0	916.0	COG2183@1|root,COG2183@2|Bacteria,2NP2S@2323|unclassified Bacteria	2|Bacteria	K	Tex-like protein N-terminal domain	yhgF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
HALNLLBL_01451	471875.RUMLAC_00382	1.64e-107	320.0	COG2116@1|root,COG2116@2|Bacteria,1TRTT@1239|Firmicutes,24BU5@186801|Clostridia,3WJFS@541000|Ruminococcaceae	186801|Clostridia	P	Formate nitrite	fnt	-	-	ko:K21993	-	-	-	-	ko00000,ko02000	1.A.16.2	-	-	Form_Nir_trans
HALNLLBL_01452	411463.EUBVEN_02418	2.68e-70	224.0	COG3859@1|root,COG3859@2|Bacteria,1V1WX@1239|Firmicutes,24E4Z@186801|Clostridia,25WJ9@186806|Eubacteriaceae	186801|Clostridia	S	proton-coupled thiamine transporter YuaJ	yuaJ	-	-	ko:K16789	-	-	-	-	ko00000,ko02000	2.A.88.3	-	-	Thia_YuaJ
HALNLLBL_01453	411470.RUMGNA_03224	1.59e-08	52.4	2EHCX@1|root,33B4S@2|Bacteria,1VKA0@1239|Firmicutes	1239|Firmicutes	S	Spore coat associated protein JA (CotJA)	-	-	-	-	-	-	-	-	-	-	-	-	CotJA
HALNLLBL_01454	272563.CD630_05970	1.87e-12	64.3	2E34J@1|root,32Y4N@2|Bacteria,1VESM@1239|Firmicutes,24QZX@186801|Clostridia	186801|Clostridia	S	COG NOG18028 non supervised orthologous group	cotJB	-	-	ko:K06333	-	-	-	-	ko00000	-	-	-	CotJB
HALNLLBL_01455	1121335.Clst_2046	3.17e-09	53.5	COG3546@1|root,COG3546@2|Bacteria	2|Bacteria	P	catalase activity	cotJC	-	-	ko:K06334,ko:K07217	-	-	-	-	ko00000	-	-	-	Mn_catalase
HALNLLBL_01456	457412.RSAG_02474	2.14e-139	402.0	COG0583@1|root,COG0583@2|Bacteria,1TRYW@1239|Firmicutes,249AX@186801|Clostridia,3WJR3@541000|Ruminococcaceae	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
HALNLLBL_01457	457412.RSAG_02475	2.02e-277	763.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,3WHBC@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
HALNLLBL_01458	1160721.RBI_II00006	2.42e-14	73.6	COG0454@1|root,COG0456@2|Bacteria,1V77V@1239|Firmicutes,24MDJ@186801|Clostridia,3WSEJ@541000|Ruminococcaceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HALNLLBL_01459	1408323.JQKK01000009_gene1154	3.19e-79	240.0	COG1670@1|root,COG1670@2|Bacteria,1V4F3@1239|Firmicutes,24EZ6@186801|Clostridia,27IX6@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_3
HALNLLBL_01460	411474.COPEUT_02494	1.39e-141	402.0	COG1305@1|root,COG1305@2|Bacteria,1TS2V@1239|Firmicutes,24AFU@186801|Clostridia	186801|Clostridia	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
HALNLLBL_01461	1410624.JNKK01000024_gene1272	7.82e-115	341.0	COG1045@1|root,COG1045@2|Bacteria,1TR42@1239|Firmicutes,249SF@186801|Clostridia,27K96@186928|unclassified Lachnospiraceae	186801|Clostridia	E	Bacterial transferase hexapeptide (six repeats)	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
HALNLLBL_01462	537013.CLOSTMETH_00694	1.64e-62	198.0	COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,24JRN@186801|Clostridia,3WJIZ@541000|Ruminococcaceae	186801|Clostridia	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
HALNLLBL_01463	411463.EUBVEN_00590	1.75e-143	422.0	COG0523@1|root,COG0523@2|Bacteria,1TPCG@1239|Firmicutes,248XD@186801|Clostridia,25VUJ@186806|Eubacteriaceae	186801|Clostridia	S	CobW P47K family protein	-	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
HALNLLBL_01465	97139.C824_02520	2.74e-110	325.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia,36E89@31979|Clostridiaceae	186801|Clostridia	E	ABC transporter	glnQ	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
HALNLLBL_01466	720554.Clocl_3766	2.93e-85	258.0	COG0765@1|root,COG0765@2|Bacteria,1V280@1239|Firmicutes,25C2S@186801|Clostridia,3WHKU@541000|Ruminococcaceae	186801|Clostridia	P	ABC transporter, permease protein	tcyB	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
HALNLLBL_01467	411469.EUBHAL_00834	8.42e-73	232.0	COG0834@1|root,COG0834@2|Bacteria,1TQNR@1239|Firmicutes,249Y5@186801|Clostridia,25VIV@186806|Eubacteriaceae	186801|Clostridia	ET	ABC transporter, substrate-binding protein, family 3	fliY1	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
HALNLLBL_01468	1519439.JPJG01000060_gene1861	7.37e-96	302.0	COG1961@1|root,COG1961@2|Bacteria,1TPBH@1239|Firmicutes,25B5K@186801|Clostridia,2N6BB@216572|Oscillospiraceae	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
HALNLLBL_01469	1105031.HMPREF1141_2503	1.46e-79	240.0	COG3546@1|root,COG3546@2|Bacteria,1TQVQ@1239|Firmicutes,247YJ@186801|Clostridia,36EF8@31979|Clostridiaceae	186801|Clostridia	P	PFAM Manganese containing catalase	cotJC	-	-	ko:K06334	-	-	-	-	ko00000	-	-	-	Mn_catalase
HALNLLBL_01471	411473.RUMCAL_00017	7.59e-22	88.6	COG0615@1|root,COG0615@2|Bacteria,1V3KY@1239|Firmicutes,24HAQ@186801|Clostridia,3WJVF@541000|Ruminococcaceae	186801|Clostridia	IM	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like
HALNLLBL_01472	1280692.AUJL01000001_gene314	1.03e-59	198.0	COG3475@1|root,COG3475@2|Bacteria,1VBSV@1239|Firmicutes,24C5H@186801|Clostridia,36EWJ@31979|Clostridiaceae	186801|Clostridia	M	LICD family	-	-	-	ko:K07271	-	-	-	-	ko00000,ko01000	-	-	-	LicD
HALNLLBL_01473	1396.DJ87_3939	7.66e-43	157.0	COG1216@1|root,COG1216@2|Bacteria,1VATJ@1239|Firmicutes,4HCW0@91061|Bacilli,1ZFI5@1386|Bacillus	91061|Bacilli	S	COG0463 Glycosyltransferases involved in cell wall biogenesis	epsJ	GO:0003674,GO:0003824,GO:0016740,GO:0016757	-	ko:K19425,ko:K19427	-	-	-	-	ko00000,ko01000,ko01003	-	GT2	-	Glycos_transf_2
HALNLLBL_01474	1280668.ATVT01000008_gene587	1.63e-21	96.3	COG1035@1|root,COG3955@1|root,COG1035@2|Bacteria,COG3955@2|Bacteria,1TQGA@1239|Firmicutes,249BE@186801|Clostridia,4BZCS@830|Butyrivibrio	186801|Clostridia	C	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7,FrhB_FdhB_C,FrhB_FdhB_N
HALNLLBL_01476	642492.Clole_0840	4.41e-21	85.1	2EFVX@1|root,339N4@2|Bacteria,1VN74@1239|Firmicutes,24VSA@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01477	696747.NIES39_A05270	3.88e-11	68.6	COG0791@1|root,COG0791@2|Bacteria,1G5E1@1117|Cyanobacteria,1HAUV@1150|Oscillatoriales	1117|Cyanobacteria	M	CHAP domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAP
HALNLLBL_01478	742733.HMPREF9469_02855	7.18e-91	275.0	COG0338@1|root,COG0338@2|Bacteria,1UBIY@1239|Firmicutes,248RN@186801|Clostridia,220NY@1506553|Lachnoclostridium	186801|Clostridia	L	COG COG0338 Site-specific DNA methylase	dam	-	2.1.1.72	ko:K06223	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	-	-	-	MethyltransfD12
HALNLLBL_01479	1487921.DP68_09000	7.62e-31	110.0	COG3655@1|root,COG3655@2|Bacteria,1VHK7@1239|Firmicutes,24R05@186801|Clostridia,36N4H@31979|Clostridiaceae	186801|Clostridia	K	Cro/C1-type HTH DNA-binding domain	-	-	-	ko:K07727	-	-	-	-	ko00000,ko03000	-	-	-	HTH_26
HALNLLBL_01480	1410626.JHXB01000031_gene1709	4.02e-31	118.0	COG2801@1|root,COG2801@2|Bacteria,1TRUP@1239|Firmicutes,24AJD@186801|Clostridia,27KEC@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve,rve_3
HALNLLBL_01481	1410628.JNKS01000056_gene562	1.4e-48	156.0	COG2963@1|root,COG2963@2|Bacteria,1VHFV@1239|Firmicutes,25BV6@186801|Clostridia,27TEF@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
HALNLLBL_01482	1235799.C818_02530	2.1e-170	489.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,27J6E@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Sodium:neurotransmitter symporter family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
HALNLLBL_01483	445972.ANACOL_03243	8.37e-30	117.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,3WHPT@541000|Ruminococcaceae	186801|Clostridia	L	Domain of unknown function (DUF4368)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
HALNLLBL_01484	97139.C824_04658	2.6e-18	84.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,36DU1@31979|Clostridiaceae	186801|Clostridia	L	Psort location Cytoplasmic, score 7.50	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
HALNLLBL_01486	318464.IO99_05385	7.27e-85	258.0	COG1131@1|root,COG1131@2|Bacteria,1V1P4@1239|Firmicutes,249VI@186801|Clostridia,36I6U@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter, ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
HALNLLBL_01489	97139.C824_04415	3.07e-20	94.7	2AIFZ@1|root,32WHS@2|Bacteria,1VBMM@1239|Firmicutes,25HS6@186801|Clostridia,36UA2@31979|Clostridiaceae	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01492	1410617.JHXH01000015_gene95	7.21e-33	116.0	COG2963@1|root,COG2963@2|Bacteria,1VC5D@1239|Firmicutes,24T2A@186801|Clostridia,3WS2S@541000|Ruminococcaceae	186801|Clostridia	L	Transposase	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
HALNLLBL_01493	1235796.C815_02341	4.59e-63	202.0	COG2801@1|root,COG2801@2|Bacteria,1TRV8@1239|Firmicutes	1239|Firmicutes	L	Integrase core domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve
HALNLLBL_01494	1123288.SOV_1c03130	1.46e-182	517.0	COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4H33R@909932|Negativicutes	1239|Firmicutes	L	Transposase, mutator	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
HALNLLBL_01495	523845.AQXV01000040_gene1689	2.85e-171	497.0	arCOG12080@1|root,arCOG12080@2157|Archaea,2Y30S@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01496	1235793.C809_01937	3.77e-23	101.0	COG1396@1|root,COG2932@1|root,COG1396@2|Bacteria,COG2932@2|Bacteria,1TQWX@1239|Firmicutes,24CWA@186801|Clostridia,27MM1@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Peptidase S24-like	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,Peptidase_S24
HALNLLBL_01497	1280664.AUIX01000038_gene2477	1.49e-05	48.1	COG0457@1|root,COG1396@1|root,COG0457@2|Bacteria,COG1396@2|Bacteria,1UJ1K@1239|Firmicutes,25G56@186801|Clostridia,4BW48@830|Butyrivibrio	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HALNLLBL_01501	445972.ANACOL_00518	1.55e-240	687.0	COG2801@1|root,COG2801@2|Bacteria,1UPNA@1239|Firmicutes,25DR7@186801|Clostridia,3WSH1@541000|Ruminococcaceae	186801|Clostridia	L	Mu transposase, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	DDE_2,HTH_Tnp_Mu_2,Mu-transpos_C,rve
HALNLLBL_01502	1160721.RBI_II00554	1.77e-66	217.0	COG2842@1|root,COG2842@2|Bacteria,1UZ2M@1239|Firmicutes,24DN9@186801|Clostridia,3WH73@541000|Ruminococcaceae	186801|Clostridia	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
HALNLLBL_01504	445972.ANACOL_00522	1.33e-31	115.0	2DP5S@1|root,330N4@2|Bacteria,1VH2J@1239|Firmicutes,24RDY@186801|Clostridia,3WM4I@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01508	552398.HMPREF0866_03127	6.7e-36	129.0	2CKR3@1|root,32SCV@2|Bacteria,1VBB0@1239|Firmicutes,24QB4@186801|Clostridia,3WJYD@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1018)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1018
HALNLLBL_01509	1499689.CCNN01000007_gene1847	1.92e-20	85.5	COG5566@1|root,COG5566@2|Bacteria,1VC4T@1239|Firmicutes,24NUM@186801|Clostridia,36VCM@31979|Clostridiaceae	186801|Clostridia	S	Mor transcription activator family	-	-	-	-	-	-	-	-	-	-	-	-	Mor
HALNLLBL_01512	742733.HMPREF9469_02884	7.79e-50	166.0	28J2K@1|root,2Z8Z1@2|Bacteria,1UYFR@1239|Firmicutes,24IKK@186801|Clostridia,221M3@1506553|Lachnoclostridium	186801|Clostridia	S	Protein of unknown function (DUF3486)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3486
HALNLLBL_01515	1105031.HMPREF1141_0088	1.12e-157	458.0	COG1783@1|root,COG1783@2|Bacteria,1TT2C@1239|Firmicutes,24A7T@186801|Clostridia,36DG1@31979|Clostridiaceae	186801|Clostridia	S	phage terminase, large subunit, PBSX family	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6,Terminase_6C
HALNLLBL_01516	411490.ANACAC_00782	2.21e-112	346.0	2BX0Z@1|root,2Z88Q@2|Bacteria,1UYMH@1239|Firmicutes,249U4@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Phage_prot_Gp6
HALNLLBL_01517	641112.ACOK01000073_gene2890	1.73e-125	388.0	COG2369@1|root,COG2369@2|Bacteria,1UZ30@1239|Firmicutes,24D0A@186801|Clostridia,3WHKX@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	ADPrib_exo_Tox,Phage_min_cap2
HALNLLBL_01519	203119.Cthe_2457	3.98e-27	99.8	2EC8I@1|root,33670@2|Bacteria,1VNEP@1239|Firmicutes,25DQM@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01520	1232449.BAHV02000010_gene2713	1.8e-08	59.3	2DQ5Z@1|root,334WJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GP20
HALNLLBL_01521	935836.JAEL01000021_gene1494	1.56e-119	354.0	2DBIJ@1|root,2Z9G2@2|Bacteria,1UXMJ@1239|Firmicutes,4HUNJ@91061|Bacilli,1ZH4G@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01524	883114.HMPREF9709_01190	1.34e-35	125.0	2C38D@1|root,3391N@2|Bacteria,1VIRX@1239|Firmicutes,25E0F@186801|Clostridia,22ISE@1570339|Peptoniphilaceae	186801|Clostridia	S	Minor capsid protein	-	-	-	-	-	-	-	-	-	-	-	-	Minor_capsid_2
HALNLLBL_01525	411473.RUMCAL_01934	1.27e-29	112.0	2D8VZ@1|root,32TS2@2|Bacteria,1VA1V@1239|Firmicutes,24JYY@186801|Clostridia,3WKG6@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Minor_capsid_3
HALNLLBL_01526	931276.Cspa_c07510	5.08e-53	172.0	2E26P@1|root,32XD4@2|Bacteria,1VDPV@1239|Firmicutes,24FU2@186801|Clostridia,36I7R@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01527	931276.Cspa_c07520	3.52e-19	84.0	2DK5T@1|root,308NQ@2|Bacteria,1VPRS@1239|Firmicutes,24PW2@186801|Clostridia,36KPN@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01528	1499683.CCFF01000017_gene2567	1.87e-51	171.0	2DJHU@1|root,32UD1@2|Bacteria,1V9ZS@1239|Firmicutes,24ECK@186801|Clostridia,36FPZ@31979|Clostridiaceae	186801|Clostridia	S	Bacteriophage Gp15 protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_Gp15
HALNLLBL_01530	33035.JPJF01000033_gene2265	2.01e-119	410.0	COG5283@1|root,COG5283@2|Bacteria,1UHQM@1239|Firmicutes,25E9Q@186801|Clostridia,3Y02N@572511|Blautia	186801|Clostridia	S	Phage-related minor tail protein	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23,PhageMin_Tail
HALNLLBL_01531	411459.RUMOBE_00925	5.11e-11	68.6	COG4722@1|root,COG4722@2|Bacteria,1VB56@1239|Firmicutes,24P9X@186801|Clostridia	186801|Clostridia	S	phage tail	-	-	-	-	-	-	-	-	-	-	-	-	Sipho_tail
HALNLLBL_01532	1391647.AVSV01000039_gene1112	1.21e-38	157.0	COG4926@1|root,COG4926@2|Bacteria,1TQHW@1239|Firmicutes,249SU@186801|Clostridia,36FUV@31979|Clostridiaceae	186801|Clostridia	M	Phage minor structural protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74,Prophage_tail
HALNLLBL_01537	1160721.RBI_II00528	9.51e-96	332.0	COG1006@1|root,COG5412@1|root,COG1006@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,247QT@186801|Clostridia,3WH3F@541000|Ruminococcaceae	186801|Clostridia	E	Phage tail tape measure protein, TP901 family	-	-	-	-	-	-	-	-	-	-	-	-	PhageMin_Tail
HALNLLBL_01539	1117108.PAALTS15_13522	2.88e-17	77.0	2EFFA@1|root,33983@2|Bacteria,1VJ6U@1239|Firmicutes,4I8G9@91061|Bacilli,26ZUH@186822|Paenibacillaceae	91061|Bacilli	S	Bacteriophage Gp15 protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_Gp15
HALNLLBL_01540	33035.JPJF01000093_gene2245	1.03e-18	81.3	2E9HP@1|root,333QS@2|Bacteria,1VJM6@1239|Firmicutes,24TQB@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01541	1282664.H354_06691	1.85e-54	175.0	2CPV6@1|root,32SJY@2|Bacteria,1VCAK@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01542	1123263.AUKY01000051_gene1075	5.52e-44	147.0	2EAWI@1|root,334XS@2|Bacteria,1VHTN@1239|Firmicutes,3VSN3@526524|Erysipelotrichia	526524|Erysipelotrichia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01543	742740.HMPREF9474_03509	3.91e-42	142.0	2CEQV@1|root,32S0A@2|Bacteria,1VBZ1@1239|Firmicutes,25D42@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01545	483218.BACPEC_01153	2.01e-22	91.7	2BVG1@1|root,32QV3@2|Bacteria,1V7ZP@1239|Firmicutes,24K5D@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01546	445972.ANACOL_01845	1.08e-131	384.0	2CGZW@1|root,2Z7Z5@2|Bacteria,1UVRJ@1239|Firmicutes,24AW4@186801|Clostridia,3WSER@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01547	552396.HMPREF0863_01634	2.49e-15	78.6	29H3I@1|root,30413@2|Bacteria,1V497@1239|Firmicutes,3VSRH@526524|Erysipelotrichia	526524|Erysipelotrichia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01550	742740.HMPREF9474_03503	7.16e-154	459.0	COG2369@1|root,COG2369@2|Bacteria,1UWB5@1239|Firmicutes,25JJT@186801|Clostridia,222WU@1506553|Lachnoclostridium	186801|Clostridia	S	Phage minor capsid protein 2	-	-	-	-	-	-	-	-	-	-	-	-	Phage_min_cap2
HALNLLBL_01551	742740.HMPREF9474_03501	3.2e-151	450.0	2DB9Q@1|root,2Z7Y9@2|Bacteria,1TRTY@1239|Firmicutes,24ANQ@186801|Clostridia,221T2@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phage_prot_Gp6
HALNLLBL_01552	1282664.H354_06621	1.17e-228	640.0	COG1783@1|root,COG1783@2|Bacteria,1UZSU@1239|Firmicutes	1239|Firmicutes	S	Phage terminase, large subunit, PBSX family	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6
HALNLLBL_01553	469604.HMPREF0946_01094	4.42e-23	94.4	COG3728@1|root,COG3728@2|Bacteria,37B93@32066|Fusobacteria	32066|Fusobacteria	L	terminase small subunit	-	-	-	ko:K07474	-	-	-	-	ko00000	-	-	-	Terminase_2
HALNLLBL_01554	1211035.CD30_08135	4.53e-14	71.6	COG1191@1|root,COG1191@2|Bacteria,1V5CD@1239|Firmicutes,4HMHU@91061|Bacilli	91061|Bacilli	K	Protein of unknown function (DUF1492)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1492
HALNLLBL_01557	1121097.JCM15093_2710	3.04e-13	69.3	2EGZP@1|root,33ART@2|Bacteria,4NYAA@976|Bacteroidetes,2FVRR@200643|Bacteroidia,4AST7@815|Bacteroidaceae	976|Bacteroidetes	S	YopX protein	-	-	-	-	-	-	-	-	-	-	-	-	YopX
HALNLLBL_01560	411462.DORLON_00806	2.03e-67	207.0	COG4570@1|root,COG4570@2|Bacteria,1V7TK@1239|Firmicutes,24JYJ@186801|Clostridia,27WTK@189330|Dorea	186801|Clostridia	L	Endodeoxyribonuclease RusA	rusA	-	-	-	-	-	-	-	-	-	-	-	RusA
HALNLLBL_01562	394503.Ccel_3304	0.0	964.0	COG3598@1|root,COG3598@2|Bacteria,1TP5Q@1239|Firmicutes,24A4I@186801|Clostridia	186801|Clostridia	L	Primase C terminal 2 (PriCT-2)	-	-	-	ko:K07505	-	-	-	-	ko00000	-	-	-	AAA_25,PriCT_2
HALNLLBL_01563	1235798.C817_03499	1.16e-304	840.0	COG1061@1|root,COG1061@2|Bacteria,1TQ62@1239|Firmicutes,249TK@186801|Clostridia,27W7J@189330|Dorea	186801|Clostridia	L	helicase superfamily c-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	HNH,Helicase_C,ResIII
HALNLLBL_01564	742723.HMPREF9477_00927	1.44e-39	139.0	2DHKB@1|root,32U9C@2|Bacteria,1VBER@1239|Firmicutes,24NR8@186801|Clostridia,27PE3@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF669
HALNLLBL_01565	1123304.AQYA01000037_gene196	8.11e-152	439.0	28HHC@1|root,2Z7T2@2|Bacteria,1TR3B@1239|Firmicutes	1239|Firmicutes	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_24
HALNLLBL_01567	645991.Sgly_0320	6.47e-175	503.0	COG1196@1|root,COG1196@2|Bacteria,1TSKM@1239|Firmicutes,24BPD@186801|Clostridia	186801|Clostridia	D	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_23
HALNLLBL_01571	207559.Dde_3430	0.00011	43.1	COG3311@1|root,COG3311@2|Bacteria,1N779@1224|Proteobacteria,42VDM@68525|delta/epsilon subdivisions,2WR6J@28221|Deltaproteobacteria,2MDKV@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	TIGRFAM DNA binding domain protein, excisionase family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
HALNLLBL_01576	663952.SDD27957_09355	4.53e-16	72.4	2EKTV@1|root,33EHJ@2|Bacteria,1VMVS@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
HALNLLBL_01577	1095750.HMPREF9970_1005	5.44e-36	132.0	COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,24AXJ@186801|Clostridia,1HW2Q@1164882|Lachnoanaerobaculum	186801|Clostridia	K	Helix-turn-helix domain	-	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	HTH_19,HTH_3,Peptidase_S24
HALNLLBL_01578	431943.CKL_3226	3.28e-48	175.0	2DZDR@1|root,32V81@2|Bacteria,1V5XJ@1239|Firmicutes,24T48@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01580	930946.AEOP01000001_gene590	5.45e-13	67.4	COG1476@1|root,COG1476@2|Bacteria,1V7I5@1239|Firmicutes,4HY57@91061|Bacilli,4AYAF@81850|Leuconostocaceae	91061|Bacilli	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HALNLLBL_01581	428125.CLOLEP_01329	7.13e-50	179.0	COG4974@1|root,COG4974@2|Bacteria,1VU9F@1239|Firmicutes,25FU1@186801|Clostridia,3WIT0@541000|Ruminococcaceae	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K14059	-	-	-	-	ko00000	-	-	-	Arm-DNA-bind_2,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase
HALNLLBL_01582	642492.Clole_0028	7.02e-25	103.0	COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes,24AMP@186801|Clostridia	186801|Clostridia	L	PFAM Transposase, IS204 IS1001 IS1096 IS1165	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
HALNLLBL_01583	478749.BRYFOR_09340	1.05e-30	119.0	COG0546@1|root,COG0546@2|Bacteria,1V1FQ@1239|Firmicutes,24G1U@186801|Clostridia	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
HALNLLBL_01584	411902.CLOBOL_01408	5.05e-53	196.0	COG3307@1|root,COG3307@2|Bacteria,1UK9W@1239|Firmicutes,25FS0@186801|Clostridia,21YND@1506553|Lachnoclostridium	186801|Clostridia	M	COG NOG20088 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
HALNLLBL_01585	428125.CLOLEP_01587	1.76e-82	257.0	COG0726@1|root,COG0726@2|Bacteria,1V6AW@1239|Firmicutes,24EU8@186801|Clostridia,3WINV@541000|Ruminococcaceae	186801|Clostridia	G	PFAM Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
HALNLLBL_01586	545695.TREAZ_0035	1.95e-40	138.0	COG0735@1|root,COG0735@2|Bacteria	2|Bacteria	P	belongs to the Fur family	fur	-	-	ko:K03711,ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
HALNLLBL_01587	1256908.HMPREF0373_02781	1.32e-95	281.0	COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,25VDD@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	rbr3A	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
HALNLLBL_01588	626939.HMPREF9443_01862	1.87e-29	104.0	COG1773@1|root,COG1773@2|Bacteria,1VEQC@1239|Firmicutes	1239|Firmicutes	C	rubredoxin	rubR2	-	-	-	-	-	-	-	-	-	-	-	Rubredoxin
HALNLLBL_01589	411463.EUBVEN_02011	1.84e-158	446.0	COG0708@1|root,COG0708@2|Bacteria,1TPFB@1239|Firmicutes,24849@186801|Clostridia,25V2W@186806|Eubacteriaceae	186801|Clostridia	L	exodeoxyribonuclease III	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
HALNLLBL_01590	545695.TREAZ_1436	2.88e-97	301.0	COG0400@1|root,COG0400@2|Bacteria,2J6EZ@203691|Spirochaetes	203691|Spirochaetes	S	Protein of unknown function (DUF2974)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2974
HALNLLBL_01591	1033837.WANG_1103	4.58e-48	167.0	COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HAYI@91061|Bacilli,3FB5V@33958|Lactobacillaceae	91061|Bacilli	L	COG2826 Transposase and inactivated derivatives, IS30 family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
HALNLLBL_01592	626939.HMPREF9443_01753	2.9e-46	154.0	COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4H4H0@909932|Negativicutes	909932|Negativicutes	L	Integrase core domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
HALNLLBL_01595	428125.CLOLEP_02625	2.21e-203	591.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia,3WGHX@541000|Ruminococcaceae	186801|Clostridia	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
HALNLLBL_01597	1123263.AUKY01000003_gene284	8.41e-19	80.9	2CF79@1|root,32RHV@2|Bacteria,1V7CD@1239|Firmicutes	1239|Firmicutes	S	Protein of unknown function (DUF1292)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1292
HALNLLBL_01598	428125.CLOLEP_02423	1.19e-38	130.0	2E6AD@1|root,330Y9@2|Bacteria,1VGZN@1239|Firmicutes,2589N@186801|Clostridia,3WM9E@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01600	428125.CLOLEP_02426	1.04e-246	691.0	COG1109@1|root,COG1109@2|Bacteria,1TS6S@1239|Firmicutes,2491F@186801|Clostridia,3WN8S@541000|Ruminococcaceae	186801|Clostridia	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II	-	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III
HALNLLBL_01601	1211844.CBLM010000142_gene3144	2.75e-34	131.0	COG1476@1|root,COG1476@2|Bacteria,1V2HC@1239|Firmicutes,3VQPV@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Bacteriophage CI repressor helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HALNLLBL_01602	357809.Cphy_3785	3e-269	761.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,24A10@186801|Clostridia,222FN@1506553|Lachnoclostridium	186801|Clostridia	G	Galactose mutarotase-like	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	DUF5110,Gal_mutarotas_2,Glyco_hydro_31
HALNLLBL_01603	573061.Clocel_2497	7.85e-64	205.0	COG2323@1|root,COG2323@2|Bacteria,1TRWQ@1239|Firmicutes,24CFP@186801|Clostridia,36EE2@31979|Clostridiaceae	186801|Clostridia	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF421
HALNLLBL_01604	428125.CLOLEP_00361	2.29e-173	488.0	COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,248CQ@186801|Clostridia,3WGC5@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
HALNLLBL_01605	428125.CLOLEP_00362	2.48e-92	279.0	COG0543@1|root,COG0543@2|Bacteria,1TQ5D@1239|Firmicutes,24AY2@186801|Clostridia,3WGW1@541000|Ruminococcaceae	186801|Clostridia	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
HALNLLBL_01606	428125.CLOLEP_00039	2.61e-44	164.0	COG5279@1|root,COG5279@2|Bacteria,1V4SN@1239|Firmicutes,24HXN@186801|Clostridia,3WKJI@541000|Ruminococcaceae	186801|Clostridia	D	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
HALNLLBL_01607	1120746.CCNL01000003_gene10	6.29e-42	161.0	COG5279@1|root,COG5279@2|Bacteria	2|Bacteria	D	protein involved in cytokinesis, contains TGc (transglutaminase protease-like) domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CW_binding_2,Cu_amine_oxidN1,DUF5050,LRR_4,SLH,Transglut_core
HALNLLBL_01608	1195236.CTER_0833	4.5e-147	453.0	COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes	1239|Firmicutes	M	Belongs to the LTA synthase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
HALNLLBL_01609	1226322.HMPREF1545_01173	7.95e-290	810.0	COG0326@1|root,COG0326@2|Bacteria,1TQEU@1239|Firmicutes,247ND@186801|Clostridia,2N70B@216572|Oscillospiraceae	186801|Clostridia	O	Hsp90 protein	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
HALNLLBL_01610	1235835.C814_01774	1.48e-282	794.0	COG3855@1|root,COG3855@2|Bacteria,1TPFU@1239|Firmicutes,248ZC@186801|Clostridia,3WGTB@541000|Ruminococcaceae	186801|Clostridia	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3	fbp	-	3.1.3.11	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_2
HALNLLBL_01612	1122917.KB899659_gene5296	2.53e-37	129.0	COG1695@1|root,COG1695@2|Bacteria,1VAKA@1239|Firmicutes,4IR4T@91061|Bacilli,276N1@186822|Paenibacillaceae	91061|Bacilli	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
HALNLLBL_01613	397291.C804_04364	3.26e-39	154.0	COG5305@1|root,COG5305@2|Bacteria,1UXXF@1239|Firmicutes,25Q2P@186801|Clostridia,27NZC@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
HALNLLBL_01614	411467.BACCAP_02989	1.42e-108	318.0	COG2304@1|root,COG2304@2|Bacteria,1TRPP@1239|Firmicutes,249HV@186801|Clostridia,26AMU@186813|unclassified Clostridiales	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01615	500632.CLONEX_01035	6.26e-150	431.0	COG2110@1|root,COG2110@2|Bacteria,1TPCU@1239|Firmicutes,24ARG@186801|Clostridia	186801|Clostridia	T	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Macro
HALNLLBL_01616	1235799.C818_03070	1.8e-54	188.0	COG3583@1|root,COG3583@2|Bacteria,1UJWV@1239|Firmicutes,25NR5@186801|Clostridia,27MWQ@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Domain of unknown function (DUF348)	-	-	-	-	-	-	-	-	-	-	-	-	DUF348,G5
HALNLLBL_01617	1235799.C818_03069	5.93e-127	384.0	COG0457@1|root,COG0457@2|Bacteria,1V0II@1239|Firmicutes,24C9M@186801|Clostridia,27IVJ@186928|unclassified Lachnospiraceae	186801|Clostridia	S	SGNH hydrolase-like domain, acetyltransferase AlgX	-	-	-	-	-	-	-	-	-	-	-	-	ALGX,DHHW
HALNLLBL_01618	1235799.C818_03068	1.51e-222	627.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,248V4@186801|Clostridia,27I82@186928|unclassified Lachnospiraceae	186801|Clostridia	M	MBOAT, membrane-bound O-acyltransferase family	-	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
HALNLLBL_01619	397290.C810_02690	1.06e-64	236.0	2DM3M@1|root,31JZR@2|Bacteria,1UJWW@1239|Firmicutes,25FCQ@186801|Clostridia,27QCQ@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01620	476272.RUMHYD_00799	2.96e-17	92.8	COG5492@1|root,COG5492@2|Bacteria,1U4RJ@1239|Firmicutes,25K63@186801|Clostridia,3Y24N@572511|Blautia	186801|Clostridia	N	Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
HALNLLBL_01625	428125.CLOLEP_00448	3.37e-34	117.0	COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes,24QNA@186801|Clostridia,3WKM9@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
HALNLLBL_01626	428125.CLOLEP_00447	1.53e-73	229.0	COG1994@1|root,COG1994@2|Bacteria,1V6D4@1239|Firmicutes,24K0D@186801|Clostridia,3WJN0@541000|Ruminococcaceae	186801|Clostridia	S	peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
HALNLLBL_01627	428125.CLOLEP_00446	1.97e-85	261.0	COG1354@1|root,COG1354@2|Bacteria,1TRW3@1239|Firmicutes,249VW@186801|Clostridia,3WJ4D@541000|Ruminococcaceae	186801|Clostridia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
HALNLLBL_01628	1120746.CCNL01000011_gene1689	6.26e-69	215.0	COG1386@1|root,COG1386@2|Bacteria,2NPPM@2323|unclassified Bacteria	2|Bacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
HALNLLBL_01629	428125.CLOLEP_00444	1.2e-26	108.0	2EMWG@1|root,33FIR@2|Bacteria,1VN82@1239|Firmicutes,24UV8@186801|Clostridia,3WR68@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF2953)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2953
HALNLLBL_01630	428125.CLOLEP_00443	6.11e-47	156.0	COG3874@1|root,COG3874@2|Bacteria,1V6H7@1239|Firmicutes,24JJ5@186801|Clostridia,3WJU2@541000|Ruminococcaceae	186801|Clostridia	S	Sporulation protein YtfJ	ytfJ	-	-	-	-	-	-	-	-	-	-	-	Spore_YtfJ
HALNLLBL_01631	428125.CLOLEP_00442	1.55e-101	312.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,3WGET@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
HALNLLBL_01632	877411.JMMA01000002_gene1249	3.54e-103	306.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,248UG@186801|Clostridia,3WHAC@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
HALNLLBL_01633	1120746.CCNL01000011_gene1695	2.08e-117	357.0	COG4799@1|root,COG4799@2|Bacteria	2|Bacteria	I	CoA carboxylase activity	mdcD	-	2.1.3.10,4.1.1.87	ko:K13932,ko:K13933,ko:K20510,ko:K20511	-	-	-	-	ko00000,ko01000,ko02000	3.B.1.1.4	-	-	Carboxyl_trans,MdcE
HALNLLBL_01634	537013.CLOSTMETH_02658	2.73e-15	73.9	COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3WK2X@541000|Ruminococcaceae	186801|Clostridia	I	Biotin-requiring enzyme	gcdC	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
HALNLLBL_01635	428125.CLOLEP_00436	5.66e-277	764.0	COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia,3WH2N@541000|Ruminococcaceae	186801|Clostridia	C	Pyruvate carboxylase, C-terminal domain subunit K01960	oadA	-	4.1.1.3	ko:K01571	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	HMGL-like,PYC_OADA
HALNLLBL_01637	877414.ATWA01000007_gene202	6.71e-51	194.0	COG4733@1|root,COG5279@1|root,COG4733@2|Bacteria,COG5279@2|Bacteria,1VU1V@1239|Firmicutes,24Y5S@186801|Clostridia,26CE8@186813|unclassified Clostridiales	2|Bacteria	G	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core,fn3
HALNLLBL_01638	877414.ATWA01000007_gene202	2.83e-71	253.0	COG4733@1|root,COG5279@1|root,COG4733@2|Bacteria,COG5279@2|Bacteria,1VU1V@1239|Firmicutes,24Y5S@186801|Clostridia,26CE8@186813|unclassified Clostridiales	2|Bacteria	G	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core,fn3
HALNLLBL_01639	500632.CLONEX_01516	1.22e-222	616.0	COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia	186801|Clostridia	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
HALNLLBL_01640	428125.CLOLEP_00059	5.83e-71	218.0	COG0440@1|root,COG0440@2|Bacteria,1V2AJ@1239|Firmicutes,24HZM@186801|Clostridia,3WJ0F@541000|Ruminococcaceae	186801|Clostridia	E	Acetolactate synthase small	ilvN	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
HALNLLBL_01641	428125.CLOLEP_00060	3.44e-280	778.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,2480U@186801|Clostridia,3WHFZ@541000|Ruminococcaceae	186801|Clostridia	H	acetolactate synthase large subunit	ilvI	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
HALNLLBL_01642	537013.CLOSTMETH_03303	3.11e-199	586.0	COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,248EH@186801|Clostridia,3WG9Y@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	cadA	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
HALNLLBL_01643	657322.FPR_17630	7.48e-38	130.0	COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,24JCN@186801|Clostridia,3WK18@541000|Ruminococcaceae	186801|Clostridia	K	regulatory protein, arsR	ziaR	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
HALNLLBL_01644	428125.CLOLEP_02666	1.23e-200	569.0	COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,2488W@186801|Clostridia,3WGXG@541000|Ruminococcaceae	186801|Clostridia	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
HALNLLBL_01645	428125.CLOLEP_02668	1.14e-82	255.0	COG1235@1|root,COG1235@2|Bacteria,1TQ8E@1239|Firmicutes,249U2@186801|Clostridia,3WIBU@541000|Ruminococcaceae	186801|Clostridia	S	Metallo-beta-lactamase domain protein	yycJ	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2
HALNLLBL_01646	537013.CLOSTMETH_01536	1.72e-56	181.0	COG1576@1|root,COG1576@2|Bacteria,1V3JM@1239|Firmicutes,24HED@186801|Clostridia,3WIDB@541000|Ruminococcaceae	186801|Clostridia	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
HALNLLBL_01647	428125.CLOLEP_02682	2.28e-221	633.0	COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,248RK@186801|Clostridia,3WG7T@541000|Ruminococcaceae	186801|Clostridia	K	Fibronectin-binding protein	FbpA	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
HALNLLBL_01648	755731.Clo1100_1250	3.59e-156	482.0	COG1203@1|root,COG1203@2|Bacteria,1TQ9B@1239|Firmicutes,248UE@186801|Clostridia,36GA4@31979|Clostridiaceae	186801|Clostridia	L	CRISPR-associated helicase Cas3	cas3	-	-	ko:K07012	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DEAD,HD,Helicase_C,ResIII
HALNLLBL_01649	1226325.HMPREF1548_04093	4.37e-95	285.0	2DBAF@1|root,2Z82V@2|Bacteria,1TPSR@1239|Firmicutes,24AI1@186801|Clostridia,36EEN@31979|Clostridiaceae	186801|Clostridia	S	CRISPR-associated protein Cas5	cas5d	-	-	ko:K19119	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Cas5d
HALNLLBL_01650	641112.ACOK01000086_gene3454	6.04e-133	410.0	COG5632@1|root,COG5632@2|Bacteria,1TR9V@1239|Firmicutes,248QA@186801|Clostridia,3WHGH@541000|Ruminococcaceae	186801|Clostridia	M	CRISPR-associated protein, Csd1 family	csd1	-	-	ko:K19117	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Csd1
HALNLLBL_01651	622312.ROSEINA2194_00006	1.88e-129	375.0	COG3649@1|root,COG3649@2|Bacteria,1TQZ8@1239|Firmicutes,248MT@186801|Clostridia	186801|Clostridia	L	CRISPR-associated protein, CT1132 family	-	-	-	ko:K19115,ko:K19118	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Cas7
HALNLLBL_01652	1195236.CTER_1854	1.32e-89	270.0	COG1468@1|root,COG1468@2|Bacteria,1TT4D@1239|Firmicutes,24B93@186801|Clostridia,3WIJ2@541000|Ruminococcaceae	186801|Clostridia	L	CRISPR-associated protein Cas4	cas4	-	3.1.12.1	ko:K07464	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Cas_Cas4
HALNLLBL_01653	1226325.HMPREF1548_04097	1.16e-160	460.0	COG1518@1|root,COG1518@2|Bacteria,1TQWG@1239|Firmicutes,24889@186801|Clostridia,36DVE@31979|Clostridiaceae	186801|Clostridia	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas1	-	-	ko:K15342	-	-	-	-	ko00000,ko02048,ko03400	-	-	-	Cas_Cas1
HALNLLBL_01654	588581.Cpap_3678	1.38e-46	151.0	COG1343@1|root,COG1343@2|Bacteria,1VAV3@1239|Firmicutes,24NZP@186801|Clostridia,3WJUV@541000|Ruminococcaceae	186801|Clostridia	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas2	-	-	ko:K09951	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cas2
HALNLLBL_01657	246199.CUS_4928	2.84e-108	329.0	COG2954@1|root,COG3911@1|root,COG2954@2|Bacteria,COG3911@2|Bacteria,1TQK3@1239|Firmicutes,24FBY@186801|Clostridia,3WJKT@541000|Ruminococcaceae	186801|Clostridia	S	CYTH	-	-	-	-	-	-	-	-	-	-	-	-	AAA_28,CYTH
HALNLLBL_01658	411463.EUBVEN_02379	2.67e-228	630.0	COG0115@1|root,COG0115@2|Bacteria,1TQQI@1239|Firmicutes,2480D@186801|Clostridia,25V2T@186806|Eubacteriaceae	186801|Clostridia	E	Branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42,4.1.3.38	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R05553,R10991	RC00006,RC00036,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
HALNLLBL_01659	658088.HMPREF0987_00083	3.42e-38	140.0	28RJ8@1|root,2ZDY4@2|Bacteria,1V64R@1239|Firmicutes,25A25@186801|Clostridia,27RQJ@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01663	428125.CLOLEP_02660	7.25e-88	271.0	COG1284@1|root,COG1284@2|Bacteria,1TRAU@1239|Firmicutes,249DE@186801|Clostridia,3WSC6@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
HALNLLBL_01664	428125.CLOLEP_02659	3e-39	135.0	COG1939@1|root,COG1939@2|Bacteria,1VA5V@1239|Firmicutes,24MR1@186801|Clostridia,3WJN8@541000|Ruminococcaceae	186801|Clostridia	J	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)	mrnC	-	-	ko:K11145	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Ribonuclease_3
HALNLLBL_01665	428125.CLOLEP_02657	8.88e-234	651.0	COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,247SP@186801|Clostridia,3WH1H@541000|Ruminococcaceae	186801|Clostridia	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
HALNLLBL_01666	428125.CLOLEP_02656	1.98e-54	171.0	COG0211@1|root,COG0211@2|Bacteria,1V6HW@1239|Firmicutes,24N3D@186801|Clostridia,3WJU0@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
HALNLLBL_01667	1120746.CCNL01000011_gene1604	3.32e-28	105.0	COG2868@1|root,COG2868@2|Bacteria	2|Bacteria	J	Cysteine protease Prp	ysxB	-	-	ko:K07584	-	-	-	-	ko00000	-	-	-	Peptidase_Prp
HALNLLBL_01668	1410670.JHXF01000003_gene1505	1.4e-42	141.0	COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,24MRS@186801|Clostridia,3WJUU@541000|Ruminococcaceae	186801|Clostridia	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
HALNLLBL_01669	428125.CLOLEP_02649	1.31e-143	411.0	COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,248DB@186801|Clostridia,3WGHP@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
HALNLLBL_01670	428125.CLOLEP_02648	3.32e-95	293.0	COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,24APG@186801|Clostridia,3WH7A@541000|Ruminococcaceae	186801|Clostridia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
HALNLLBL_01671	1105031.HMPREF1141_3028	1.07e-168	486.0	COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,248HT@186801|Clostridia,36DH6@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the peptidase M16 family	ymfH	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
HALNLLBL_01672	428125.CLOLEP_02646	3.84e-123	370.0	COG0612@1|root,COG0612@2|Bacteria,1TPN6@1239|Firmicutes,248J8@186801|Clostridia,3WHRP@541000|Ruminococcaceae	186801|Clostridia	S	Peptidase M16 inactive domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16_C
HALNLLBL_01673	500633.CLOHIR_00090	3.95e-64	203.0	COG0110@1|root,COG0110@2|Bacteria,1TQEX@1239|Firmicutes,249KF@186801|Clostridia,25SQA@186804|Peptostreptococcaceae	186801|Clostridia	H	Psort location Cytoplasmic, score 9.98	-	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2,Mac
HALNLLBL_01675	1211817.CCAT010000009_gene841	2.54e-80	245.0	COG0546@1|root,COG0546@2|Bacteria,1V4W6@1239|Firmicutes,24DB6@186801|Clostridia,36VFQ@31979|Clostridiaceae	186801|Clostridia	S	IA, variant 1	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
HALNLLBL_01678	479437.Elen_2186	1.6e-76	244.0	COG2755@1|root,COG2755@2|Bacteria,2HUFA@201174|Actinobacteria,4CUEM@84998|Coriobacteriia	84998|Coriobacteriia	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01679	1123313.ATUT01000031_gene1457	2.61e-183	531.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,3VP7P@526524|Erysipelotrichia	526524|Erysipelotrichia	M	MBOAT, membrane-bound O-acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
HALNLLBL_01680	883114.HMPREF9709_01432	1.86e-30	108.0	COG0236@1|root,COG0236@2|Bacteria,1VEX6@1239|Firmicutes,24QWP@186801|Clostridia	186801|Clostridia	IQ	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
HALNLLBL_01681	883114.HMPREF9709_01433	1.16e-140	413.0	COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,247X7@186801|Clostridia,22HZN@1570339|Peptoniphilaceae	186801|Clostridia	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
HALNLLBL_01682	877414.ATWA01000004_gene563	5.85e-207	590.0	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,2490U@186801|Clostridia	186801|Clostridia	Q	Belongs to the ATP-dependent AMP-binding enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,PP-binding
HALNLLBL_01683	1151292.QEW_1398	1.49e-50	185.0	COG0642@1|root,COG2205@2|Bacteria,1UYC9@1239|Firmicutes,24CPQ@186801|Clostridia,25TFB@186804|Peptostreptococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
HALNLLBL_01684	877414.ATWA01000081_gene1176	6.24e-78	241.0	COG0745@1|root,COG0745@2|Bacteria,1TR8K@1239|Firmicutes,24973@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HALNLLBL_01685	1408304.JAHA01000013_gene354	3.23e-64	215.0	COG1226@1|root,COG1226@2|Bacteria	2|Bacteria	P	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)	dMI1	-	3.1.4.46	ko:K01126,ko:K10716	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Castor_Poll_mid,TrkA_N
HALNLLBL_01687	1392493.JIAB01000001_gene1584	1.49e-59	204.0	COG3274@1|root,COG3274@2|Bacteria,1V9EN@1239|Firmicutes,25CM5@186801|Clostridia,27U5U@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
HALNLLBL_01688	552396.HMPREF0863_00660	6.69e-285	820.0	COG1215@1|root,COG1887@1|root,COG1215@2|Bacteria,COG1887@2|Bacteria,1UYH3@1239|Firmicutes	1239|Firmicutes	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Glyphos_transf
HALNLLBL_01689	411463.EUBVEN_01214	3.88e-93	275.0	COG4475@1|root,COG4475@2|Bacteria,1V3H0@1239|Firmicutes,24HEU@186801|Clostridia,25WKB@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF436)	-	-	-	-	-	-	-	-	-	-	-	-	DUF436
HALNLLBL_01690	515620.EUBELI_20348	4.08e-227	631.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,25UQC@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	fucO	-	1.1.1.1,1.1.1.77	ko:K00048,ko:K13954	ko00010,ko00071,ko00350,ko00625,ko00626,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00630,map00640,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R01781,R02257,R04880,R05233,R05234,R06917,R06927	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
HALNLLBL_01691	1235793.C809_01817	2.73e-66	206.0	COG0454@1|root,COG0456@2|Bacteria,1V77V@1239|Firmicutes,24MDJ@186801|Clostridia,27MDF@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HALNLLBL_01692	411467.BACCAP_03491	0.0	1020.0	COG0480@1|root,COG3688@1|root,COG0480@2|Bacteria,COG3688@2|Bacteria,1TPQH@1239|Firmicutes,247X4@186801|Clostridia,26843@186813|unclassified Clostridiales	186801|Clostridia	J	Elongation factor G, domain IV	tetP	-	-	-	-	-	-	-	-	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,NYN_YacP
HALNLLBL_01693	1499967.BAYZ01000016_gene6478	1.07e-179	513.0	COG0436@1|root,COG0436@2|Bacteria,2NQG2@2323|unclassified Bacteria	2|Bacteria	E	Aminotransferase class I and II	dapL	-	2.6.1.83	ko:K10206,ko:K14261	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
HALNLLBL_01695	1235797.C816_00624	1.21e-54	174.0	COG0242@1|root,COG0242@2|Bacteria,1V73T@1239|Firmicutes,24FT0@186801|Clostridia,2N7D7@216572|Oscillospiraceae	186801|Clostridia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins	def2	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
HALNLLBL_01697	500632.CLONEX_03122	2.54e-71	218.0	COG0789@1|root,COG0789@2|Bacteria,1V3QI@1239|Firmicutes,25B3D@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
HALNLLBL_01699	515620.EUBELI_20326	2.98e-70	226.0	COG4667@1|root,COG4667@2|Bacteria,1TQ9W@1239|Firmicutes,2485C@186801|Clostridia,25VW9@186806|Eubacteriaceae	186801|Clostridia	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
HALNLLBL_01700	1211819.CALK01000034_gene176	7.38e-18	85.5	COG1309@1|root,COG1309@2|Bacteria,1VC54@1239|Firmicutes,3VUFT@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Transcriptional regulator C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
HALNLLBL_01701	1410638.JHXJ01000001_gene1913	1.04e-83	256.0	COG0655@1|root,COG0655@2|Bacteria,1TRKM@1239|Firmicutes,24AD6@186801|Clostridia,3WJYP@541000|Ruminococcaceae	186801|Clostridia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red,Flavodoxin_2,SCP2
HALNLLBL_01702	515620.EUBELI_20279	5.15e-61	192.0	COG0764@1|root,COG0764@2|Bacteria,1VWSM@1239|Firmicutes,252FM@186801|Clostridia	186801|Clostridia	I	K02372 3R-hydroxymyristoyl ACP dehydrase	-	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
HALNLLBL_01703	1410638.JHXJ01000001_gene1912	2.14e-107	317.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,3WGIW@541000|Ruminococcaceae	186801|Clostridia	IQ	reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
HALNLLBL_01704	1410638.JHXJ01000001_gene1911	9.01e-265	756.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,3WGGB@541000|Ruminococcaceae	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
HALNLLBL_01705	1410638.JHXJ01000001_gene1910	3.98e-26	98.6	COG0236@1|root,COG0236@2|Bacteria,1W4GV@1239|Firmicutes,255Z4@186801|Clostridia	186801|Clostridia	IQ	Phosphopantetheine attachment site	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
HALNLLBL_01706	511680.BUTYVIB_00785	4.54e-32	123.0	COG0204@1|root,COG0204@2|Bacteria,1V4XW@1239|Firmicutes	1239|Firmicutes	I	Acyltransferase	plsD	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
HALNLLBL_01707	903814.ELI_0510	6.22e-148	428.0	COG3049@1|root,COG3049@2|Bacteria,1TRTI@1239|Firmicutes,24AFG@186801|Clostridia,25X6F@186806|Eubacteriaceae	186801|Clostridia	M	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	AAT,CBAH
HALNLLBL_01708	478749.BRYFOR_09130	9.49e-140	414.0	COG3290@1|root,COG3290@2|Bacteria,1UY02@1239|Firmicutes,24BV9@186801|Clostridia	186801|Clostridia	T	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
HALNLLBL_01709	1235802.C823_01109	1.66e-87	266.0	COG3279@1|root,COG3279@2|Bacteria,1VA5A@1239|Firmicutes,24C2K@186801|Clostridia,25WVY@186806|Eubacteriaceae	186801|Clostridia	K	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
HALNLLBL_01710	97139.C824_00384	0.0	950.0	COG2015@1|root,COG2015@2|Bacteria,1TR7Q@1239|Firmicutes,248SN@186801|Clostridia,36K01@31979|Clostridiaceae	186801|Clostridia	Q	Alkyl sulfatase dimerisation	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_C,Alkyl_sulf_dimr,Lactamase_B
HALNLLBL_01714	471875.RUMLAC_00918	5.79e-125	363.0	COG0388@1|root,COG0388@2|Bacteria,1TRMU@1239|Firmicutes,24EKU@186801|Clostridia,3WRXC@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
HALNLLBL_01715	1384066.JAGT01000001_gene1072	6.63e-91	292.0	COG1131@1|root,COG1131@2|Bacteria,1V0ED@1239|Firmicutes,24BB5@186801|Clostridia,3WJBX@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran,FHA
HALNLLBL_01716	1410617.JHXH01000002_gene1801	1.08e-53	182.0	COG0842@1|root,COG0842@2|Bacteria,1UZ9R@1239|Firmicutes,24EYY@186801|Clostridia,3WKU7@541000|Ruminococcaceae	186801|Clostridia	V	ABC-2 type transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane
HALNLLBL_01717	641112.ACOK01000054_gene3785	6.37e-48	167.0	COG0631@1|root,COG0631@2|Bacteria,1VXKJ@1239|Firmicutes,2522X@186801|Clostridia,3WK7B@541000|Ruminococcaceae	186801|Clostridia	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PP2C,PP2C_2
HALNLLBL_01718	658655.HMPREF0988_01687	9.43e-96	317.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,24BJ8@186801|Clostridia,27IRK@186928|unclassified Lachnospiraceae	186801|Clostridia	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PASTA,Pkinase,YARHG
HALNLLBL_01719	1211844.CBLM010000078_gene2605	5.84e-60	197.0	COG4990@1|root,COG4990@2|Bacteria,1V6DF@1239|Firmicutes,3VTAG@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
HALNLLBL_01721	879308.HMPREF9130_1029	1.31e-98	296.0	COG2267@1|root,COG2267@2|Bacteria,1TRM1@1239|Firmicutes,247J5@186801|Clostridia,22GBA@1570339|Peptoniphilaceae	186801|Clostridia	I	Hydrolase, alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
HALNLLBL_01722	1120746.CCNL01000010_gene1304	1.52e-54	177.0	COG0700@1|root,COG0700@2|Bacteria,2NPSZ@2323|unclassified Bacteria	2|Bacteria	S	Nucleoside recognition	spmB	-	-	ko:K06374	-	-	-	-	ko00000	-	-	-	Gate
HALNLLBL_01723	1105031.HMPREF1141_2072	1.71e-58	189.0	COG2715@1|root,COG2715@2|Bacteria,1V1E2@1239|Firmicutes,249G0@186801|Clostridia,36E11@31979|Clostridiaceae	186801|Clostridia	S	Spore maturation protein	spmA	-	-	ko:K06373	-	-	-	-	ko00000	-	-	-	Gate
HALNLLBL_01725	428125.CLOLEP_02917	6.5e-83	248.0	COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,24HF0@186801|Clostridia,3WJ3A@541000|Ruminococcaceae	186801|Clostridia	F	MafB19-like deaminase	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
HALNLLBL_01726	1485543.JMME01000006_gene442	9.99e-18	85.5	COG2091@1|root,COG2091@2|Bacteria,1VEYZ@1239|Firmicutes,4H6EH@909932|Negativicutes	909932|Negativicutes	H	4'-phosphopantetheinyl transferase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	ACPS
HALNLLBL_01727	641112.ACOK01000112_gene2150	4.22e-59	189.0	COG1309@1|root,COG1309@2|Bacteria,1V73E@1239|Firmicutes,25B5N@186801|Clostridia,3WJEZ@541000|Ruminococcaceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HALNLLBL_01728	203119.Cthe_1480	5.93e-317	885.0	COG1033@1|root,COG1033@2|Bacteria,1VSWA@1239|Firmicutes,247R6@186801|Clostridia,3WGDU@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
HALNLLBL_01729	428125.CLOLEP_03047	6.25e-106	348.0	COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,24A8K@186801|Clostridia,3WGGJ@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cellwall, score	-	-	-	ko:K01421	-	-	-	-	ko00000	-	-	-	-
HALNLLBL_01730	537013.CLOSTMETH_01642	4.64e-29	104.0	2BX75@1|root,32YCI@2|Bacteria,1VEDY@1239|Firmicutes,24QPW@186801|Clostridia,3WKRS@541000|Ruminococcaceae	186801|Clostridia	S	Small, acid-soluble spore protein, alpha beta type	-	-	-	-	-	-	-	-	-	-	-	-	SASP
HALNLLBL_01732	1120746.CCNL01000009_gene1018	2.73e-279	778.0	COG0119@1|root,COG0119@2|Bacteria,2NNNZ@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	GO:0000287,GO:0003674,GO:0003824,GO:0003852,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0019752,GO:0030145,GO:0030955,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0046912,GO:0046914,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iYL1228.KPN_03016	HMGL-like,LeuA_dimer
HALNLLBL_01733	873513.HMPREF6485_0820	5.75e-145	459.0	COG0366@1|root,COG0366@2|Bacteria	2|Bacteria	G	hydrolase activity, hydrolyzing O-glycosyl compounds	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CBM26,SLH
HALNLLBL_01734	428125.CLOLEP_02820	5.59e-213	596.0	COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,2487U@186801|Clostridia,3WG9F@541000|Ruminococcaceae	186801|Clostridia	C	Malic enzyme, NAD binding domain	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
HALNLLBL_01735	483218.BACPEC_02993	9.84e-167	488.0	COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,1TPM3@1239|Firmicutes,248UY@186801|Clostridia,268X5@186813|unclassified Clostridiales	186801|Clostridia	E	Psort location CytoplasmicMembrane, score	ArtM	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1,SBP_bac_3
HALNLLBL_01736	1304866.K413DRAFT_5141	5.06e-124	359.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia,36E89@31979|Clostridiaceae	186801|Clostridia	E	ABC transporter	glnQ	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
HALNLLBL_01737	742723.HMPREF9477_01976	4.68e-127	381.0	COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,247XC@186801|Clostridia,27IW0@186928|unclassified Lachnospiraceae	186801|Clostridia	J	tRNA nucleotidyltransferase domain 2 putative	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
HALNLLBL_01738	479437.Elen_1182	2.8e-227	664.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4CUZ9@84998|Coriobacteriia	84998|Coriobacteriia	P	E1-E2 ATPase	-	-	-	ko:K12952	-	-	-	-	ko00000,ko01000	3.A.3.23	-	-	E1-E2_ATPase,Hydrolase
HALNLLBL_01739	537013.CLOSTMETH_00507	9.07e-78	251.0	COG0750@1|root,COG0750@2|Bacteria,1TPIR@1239|Firmicutes,24AFA@186801|Clostridia,3WHID@541000|Ruminococcaceae	186801|Clostridia	M	Stage IV sporulation protein B	spoIVB	-	3.4.21.116	ko:K06399	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S55
HALNLLBL_01740	428125.CLOLEP_03274	4.23e-109	322.0	COG2201@1|root,COG2201@2|Bacteria,1VQS3@1239|Firmicutes,25E3X@186801|Clostridia,3WGU4@541000|Ruminococcaceae	186801|Clostridia	NT	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process	spo0A	-	-	ko:K03413,ko:K07699	ko02020,ko02024,ko02030,map02020,map02024,map02030	M00485,M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg,Spo0A_C
HALNLLBL_01741	1120746.CCNL01000011_gene1811	7.67e-226	631.0	COG0151@1|root,COG0151@2|Bacteria,2NP0B@2323|unclassified Bacteria	2|Bacteria	F	Belongs to the GARS family	purD	-	6.3.2.6,6.3.4.13	ko:K01945,ko:K13713	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04591	RC00064,RC00090,RC00162,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
HALNLLBL_01742	483215.BACFIN_06508	8.18e-239	661.0	COG0138@1|root,COG0138@2|Bacteria,4NIY8@976|Bacteroidetes,2FMYP@200643|Bacteroidia,4AKEJ@815|Bacteroidaceae	976|Bacteroidetes	F	COG0138 AICAR transformylase IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful)	purH2	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas
HALNLLBL_01743	1160721.RBI_II00077	7.9e-128	368.0	COG3363@1|root,COG3363@2|Bacteria,1TRA7@1239|Firmicutes,249ZW@186801|Clostridia,3WGGF@541000|Ruminococcaceae	186801|Clostridia	F	IMP cyclohydrolase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	IMP_cyclohyd
HALNLLBL_01744	428125.CLOLEP_02079	1.08e-94	281.0	COG0299@1|root,COG0299@2|Bacteria,1V3RJ@1239|Firmicutes,249JC@186801|Clostridia,3WIAG@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS04225	Formyl_trans_N
HALNLLBL_01745	428125.CLOLEP_02078	3.5e-184	519.0	COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,248BT@186801|Clostridia,3WHKH@541000|Ruminococcaceae	186801|Clostridia	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
HALNLLBL_01746	428125.CLOLEP_02077	2.45e-172	500.0	COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,247RF@186801|Clostridia,3WH6T@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
HALNLLBL_01747	1160721.RBI_II00083	6.72e-75	228.0	COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,24HCB@186801|Clostridia,3WITM@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
HALNLLBL_01748	1235800.C819_01113	4.29e-78	258.0	COG4905@1|root,COG4905@2|Bacteria,1TQUM@1239|Firmicutes,25CKD@186801|Clostridia,27J1N@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Putative ABC-transporter type IV	-	-	-	-	-	-	-	-	-	-	-	-	ABC_trans_CmpB
HALNLLBL_01749	428125.CLOLEP_02073	1.41e-110	327.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia,3WH9Z@541000|Ruminococcaceae	186801|Clostridia	O	SPFH Band 7 PHB domain protein	qmcA	-	-	-	-	-	-	-	-	-	-	-	Band_7
HALNLLBL_01750	1120985.AUMI01000018_gene3005	1.03e-89	282.0	COG2508@1|root,COG2508@2|Bacteria,1TSQP@1239|Firmicutes,4H48M@909932|Negativicutes	909932|Negativicutes	QT	Purine catabolism regulatory protein-like family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30,PucR
HALNLLBL_01751	1408436.JHXY01000029_gene1849	4.17e-78	239.0	COG1102@1|root,COG1102@2|Bacteria,1V1PJ@1239|Firmicutes,24GMN@186801|Clostridia,25WQM@186806|Eubacteriaceae	186801|Clostridia	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
HALNLLBL_01752	887929.HMP0721_0285	4.7e-268	738.0	COG0624@1|root,COG0624@2|Bacteria,1TQ0P@1239|Firmicutes,24BF2@186801|Clostridia,25WJU@186806|Eubacteriaceae	186801|Clostridia	E	Peptidase family M28	-	-	3.5.1.6,3.5.1.87,3.5.3.9	ko:K02083,ko:K06016	ko00230,ko00240,ko01100,ko01120,map00230,map00240,map01100,map01120	M00046	R00905,R02423,R04666	RC00064,RC00096	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
HALNLLBL_01753	1196322.A370_01717	2.61e-224	634.0	COG0167@1|root,COG1146@1|root,COG0167@2|Bacteria,COG1146@2|Bacteria,1TRPI@1239|Firmicutes,24A0Z@186801|Clostridia,36EA4@31979|Clostridiaceae	186801|Clostridia	C	dihydroorotate dehydrogenase	preA	-	1.3.1.1	ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	M00046	R00977,R01414,R11026	RC00072,RC00123	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh,Fer4_20,Fer4_21,Fer4_6
HALNLLBL_01754	633697.EubceDRAFT1_2335	7.57e-290	796.0	COG0044@1|root,COG0044@2|Bacteria,1TP8C@1239|Firmicutes,249W6@186801|Clostridia,25VQD@186806|Eubacteriaceae	186801|Clostridia	F	Amidohydrolase family	hydA_1	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1,Urease_alpha
HALNLLBL_01755	633697.EubceDRAFT1_2334	4.73e-176	501.0	COG0715@1|root,COG0715@2|Bacteria,1TPAD@1239|Firmicutes,24A2V@186801|Clostridia	186801|Clostridia	P	ABC-type nitrate sulfonate bicarbonate transport	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
HALNLLBL_01756	1449050.JNLE01000003_gene2646	1.24e-108	322.0	COG0600@1|root,COG0600@2|Bacteria,1TRRJ@1239|Firmicutes,24EZD@186801|Clostridia,36FWK@31979|Clostridiaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
HALNLLBL_01757	1449050.JNLE01000003_gene2645	4.47e-120	352.0	COG0600@1|root,COG0600@2|Bacteria,1UPIJ@1239|Firmicutes,24B1E@186801|Clostridia,36FKC@31979|Clostridiaceae	186801|Clostridia	P	binding-protein-dependent transport	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
HALNLLBL_01758	1408436.JHXY01000029_gene1856	5.57e-140	401.0	COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,248CG@186801|Clostridia,25W47@186806|Eubacteriaceae	186801|Clostridia	P	ABC-type nitrate sulfonate bicarbonate transport system, ATPase component	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
HALNLLBL_01759	633697.EubceDRAFT1_2330	4.51e-159	459.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,25UQC@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
HALNLLBL_01760	1408436.JHXY01000029_gene1858	9.09e-273	751.0	COG0161@1|root,COG0161@2|Bacteria,1TP9N@1239|Firmicutes,25E7B@186801|Clostridia,25ZRJ@186806|Eubacteriaceae	186801|Clostridia	H	Aminotransferase class-III	bioA	-	2.6.1.113,2.6.1.55,2.6.1.62,2.6.1.77	ko:K00833,ko:K03851,ko:K12256,ko:K15372	ko00330,ko00410,ko00430,ko00780,ko01100,map00330,map00410,map00430,map00780,map01100	M00123,M00573,M00577	R00908,R01684,R03231,R05652,R08714	RC00006,RC00008,RC00062,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
HALNLLBL_01762	469596.HMPREF9488_03505	6.98e-91	273.0	COG0745@1|root,COG0745@2|Bacteria,1TT73@1239|Firmicutes,3VR04@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HALNLLBL_01763	1226325.HMPREF1548_02526	1.23e-83	273.0	COG0642@1|root,COG2205@2|Bacteria,1TRD2@1239|Firmicutes,247M3@186801|Clostridia,36EWQ@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
HALNLLBL_01765	1235835.C814_01868	6.46e-85	267.0	COG2348@1|root,COG2348@2|Bacteria,1TRZU@1239|Firmicutes,24AU8@186801|Clostridia,3WI7M@541000|Ruminococcaceae	186801|Clostridia	V	Methicillin resistance	femX	-	2.3.2.10,2.3.2.16	ko:K05363,ko:K11693	ko00550,ko01100,map00550,map01100	-	R08776,R08779	RC00055,RC00096	ko00000,ko00001,ko01000,ko01011	-	-	-	FemAB
HALNLLBL_01766	97138.C820_02726	7.05e-59	196.0	COG0613@1|root,COG0613@2|Bacteria,1TPI5@1239|Firmicutes,248H2@186801|Clostridia,36DX7@31979|Clostridiaceae	186801|Clostridia	S	PHP domain	trpH	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
HALNLLBL_01767	428125.CLOLEP_03693	2.53e-133	385.0	COG0157@1|root,COG0157@2|Bacteria,1TPQC@1239|Firmicutes,248P2@186801|Clostridia,3WGJ1@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12010	QRPTase_C,QRPTase_N
HALNLLBL_01768	428125.CLOLEP_03694	8.92e-210	596.0	COG0029@1|root,COG0029@2|Bacteria,1UHSP@1239|Firmicutes,25E6F@186801|Clostridia,3WGEV@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
HALNLLBL_01769	411470.RUMGNA_01877	7.99e-19	78.6	2EG1V@1|root,339TV@2|Bacteria,1VKAZ@1239|Firmicutes,24UGV@186801|Clostridia,3Y0SX@572511|Blautia	186801|Clostridia	S	COG NOG17973 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF4250
HALNLLBL_01770	697329.Rumal_1672	7.75e-99	303.0	COG2334@1|root,COG2334@2|Bacteria,1UM1H@1239|Firmicutes	1239|Firmicutes	S	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response	-	-	-	-	-	-	-	-	-	-	-	-	APH
HALNLLBL_01771	658088.HMPREF0987_00761	3.53e-89	263.0	COG0537@1|root,COG0537@2|Bacteria,1V7FG@1239|Firmicutes,24H6W@186801|Clostridia,27M77@186928|unclassified Lachnospiraceae	186801|Clostridia	FG	histidine triad	-	-	-	-	-	-	-	-	-	-	-	-	HIT
HALNLLBL_01772	568816.Acin_0978	0.0	986.0	COG3513@1|root,COG3513@2|Bacteria,1TPSD@1239|Firmicutes,4H6PU@909932|Negativicutes	909932|Negativicutes	L	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer	cas9	-	-	ko:K09952	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Cas9-BH,Cas9_PI,Cas9_REC,HNH_4
HALNLLBL_01773	1408324.JNJK01000037_gene3743	7.91e-123	359.0	COG1518@1|root,COG1518@2|Bacteria,1TT0J@1239|Firmicutes,24CB1@186801|Clostridia,27K7W@186928|unclassified Lachnospiraceae	186801|Clostridia	L	CRISPR associated protein Cas1	cas1	-	-	-	-	-	-	-	-	-	-	-	Cas_Cas1
HALNLLBL_01774	1256908.HMPREF0373_02529	6.03e-41	137.0	COG3512@1|root,COG3512@2|Bacteria,1VEH4@1239|Firmicutes,24N00@186801|Clostridia,25XTI@186806|Eubacteriaceae	186801|Clostridia	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas2	-	-	ko:K09951	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cas2
HALNLLBL_01776	411473.RUMCAL_00299	2.01e-43	144.0	COG0593@1|root,COG0593@2|Bacteria,1V9B2@1239|Firmicutes,24JGM@186801|Clostridia,3WKS6@541000|Ruminococcaceae	186801|Clostridia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01779	1410625.JHWK01000002_gene66	7.82e-57	186.0	2EA6W@1|root,334BM@2|Bacteria,1VGW9@1239|Firmicutes,24R9J@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01780	471875.RUMLAC_01580	2.94e-41	140.0	2ADNG@1|root,309XR@2|Bacteria,1U5WF@1239|Firmicutes,259VM@186801|Clostridia,3WQSE@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01781	1232453.BAIF02000013_gene3263	7.01e-117	355.0	COG0642@1|root,COG2205@2|Bacteria,1UHUJ@1239|Firmicutes,25E2Z@186801|Clostridia,268QD@186813|unclassified Clostridiales	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	dltS	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
HALNLLBL_01782	1232453.BAIF02000013_gene3262	8.02e-113	329.0	COG0745@1|root,COG0745@2|Bacteria,1TPU2@1239|Firmicutes,24B71@186801|Clostridia,268VA@186813|unclassified Clostridiales	186801|Clostridia	KT	Transcriptional regulatory protein, C terminal	dltR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HALNLLBL_01786	1392491.JIAE01000001_gene1115	3.7e-56	186.0	COG1451@1|root,COG1451@2|Bacteria,1V6WP@1239|Firmicutes,24JGH@186801|Clostridia,3WJ8S@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
HALNLLBL_01787	511680.BUTYVIB_01219	1.99e-202	573.0	COG0534@1|root,COG0534@2|Bacteria,1TP5P@1239|Firmicutes,247PQ@186801|Clostridia,4BXUR@830|Butyrivibrio	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HALNLLBL_01788	1408304.JAHA01000006_gene768	9.41e-97	284.0	COG0406@1|root,COG0406@2|Bacteria,1V25J@1239|Firmicutes,24FZT@186801|Clostridia,4BXR3@830|Butyrivibrio	186801|Clostridia	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
HALNLLBL_01789	1392493.JIAB01000001_gene1643	2.3e-83	249.0	COG1335@1|root,COG1335@2|Bacteria,1V1CY@1239|Firmicutes,24HQM@186801|Clostridia,27MPZ@186928|unclassified Lachnospiraceae	186801|Clostridia	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
HALNLLBL_01790	428125.CLOLEP_01742	1.65e-82	248.0	COG2002@1|root,COG2002@2|Bacteria,1V02A@1239|Firmicutes,248XR@186801|Clostridia,3WITH@541000|Ruminococcaceae	186801|Clostridia	K	stage V sporulation protein T	spoVT	-	-	ko:K04769	-	-	-	-	ko00000,ko03000	-	-	-	MazE_antitoxin,SpoVT_C
HALNLLBL_01791	411461.DORFOR_02064	8.71e-196	553.0	COG1457@1|root,COG1457@2|Bacteria,1TTBN@1239|Firmicutes,248EP@186801|Clostridia,27VZ9@189330|Dorea	186801|Clostridia	F	COG COG1457 Purine-cytosine permease and related proteins	cytX	-	-	-	-	-	-	-	-	-	-	-	Transp_cyt_pur
HALNLLBL_01792	411461.DORFOR_02063	3.34e-147	419.0	COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,2483H@186801|Clostridia,27UR1@189330|Dorea	186801|Clostridia	H	Carbohydrate kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
HALNLLBL_01793	1235799.C818_03342	8.82e-70	219.0	COG0637@1|root,COG0637@2|Bacteria,1V1DF@1239|Firmicutes,24DES@186801|Clostridia,27N5M@186928|unclassified Lachnospiraceae	186801|Clostridia	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
HALNLLBL_01794	411474.COPEUT_00172	2.04e-105	309.0	COG0352@1|root,COG0352@2|Bacteria,1V3ZR@1239|Firmicutes,24DG3@186801|Clostridia	186801|Clostridia	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
HALNLLBL_01795	1392493.JIAB01000001_gene949	1.4e-159	451.0	COG2145@1|root,COG2145@2|Bacteria,1V1R6@1239|Firmicutes,248AC@186801|Clostridia,27IRB@186928|unclassified Lachnospiraceae	186801|Clostridia	H	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)	thiM	-	2.7.1.50	ko:K00878	ko00730,ko01100,map00730,map01100	M00127	R04448	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HK
HALNLLBL_01797	411474.COPEUT_00070	1.33e-294	807.0	COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,247Q3@186801|Clostridia	186801|Clostridia	P	Potassium uptake protein	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
HALNLLBL_01798	411474.COPEUT_00069	8.02e-144	406.0	COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,249C2@186801|Clostridia	186801|Clostridia	P	domain protein	ktrA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
HALNLLBL_01799	411474.COPEUT_00068	2.63e-48	154.0	2FJ5Y@1|root,34AW2@2|Bacteria,1W1C4@1239|Firmicutes,253GU@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01800	411474.COPEUT_00067	0.0	1236.0	COG0642@1|root,COG2205@2|Bacteria,1TQHB@1239|Firmicutes,247S4@186801|Clostridia	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA,KdpD
HALNLLBL_01801	411474.COPEUT_00066	4.14e-164	459.0	COG0745@1|root,COG0745@2|Bacteria,1UDAQ@1239|Firmicutes,249RQ@186801|Clostridia	186801|Clostridia	KT	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HALNLLBL_01802	537013.CLOSTMETH_01432	2.93e-72	225.0	COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249Z9@186801|Clostridia,3WI5H@541000|Ruminococcaceae	186801|Clostridia	F	Cytidylate kinase-like family	-	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin2
HALNLLBL_01804	428125.CLOLEP_00567	1.14e-53	172.0	COG0593@1|root,COG0593@2|Bacteria,1VAFE@1239|Firmicutes,25E3U@186801|Clostridia,3WSQ8@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01805	428125.CLOLEP_00566	9.51e-256	709.0	COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia,3WHJX@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
HALNLLBL_01806	428125.CLOLEP_00565	5.07e-148	431.0	COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,249B3@186801|Clostridia,3WHE1@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	dacF	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
HALNLLBL_01807	1121344.JHZO01000004_gene1320	1.48e-14	76.6	2CEVT@1|root,33HY0@2|Bacteria,1VNS9@1239|Firmicutes,24VZX@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01808	1410630.JNKP01000001_gene1953	1.25e-73	225.0	COG0245@1|root,COG0245@2|Bacteria,1V3P0@1239|Firmicutes,24HCM@186801|Clostridia,27M94@186928|unclassified Lachnospiraceae	186801|Clostridia	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
HALNLLBL_01809	877414.ATWA01000002_gene1049	7.1e-56	185.0	COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,248E6@186801|Clostridia,269H3@186813|unclassified Clostridiales	186801|Clostridia	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS20335	IspD
HALNLLBL_01810	518637.EUBIFOR_00899	6.17e-248	687.0	COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,3VPVX@526524|Erysipelotrichia	526524|Erysipelotrichia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Cys_Met_Meta_PP
HALNLLBL_01813	756499.Desde_0485	4.83e-26	97.4	COG1476@1|root,COG1476@2|Bacteria,1VEIS@1239|Firmicutes,24R6J@186801|Clostridia,265K6@186807|Peptococcaceae	186801|Clostridia	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HALNLLBL_01814	1120746.CCNL01000017_gene2929	8.71e-83	250.0	COG0452@1|root,COG0452@2|Bacteria,2NRM0@2323|unclassified Bacteria	2|Bacteria	H	Flavoprotein	spoVFB	-	-	ko:K06411	-	-	-	-	ko00000	-	-	-	Flavoprotein
HALNLLBL_01815	1120746.CCNL01000017_gene2928	1.86e-81	254.0	COG0111@1|root,COG0111@2|Bacteria	2|Bacteria	EH	4-phosphoerythronate dehydrogenase activity	spoVFA	-	-	ko:K06410	-	-	-	-	ko00000	-	-	-	2-Hacid_dh_C,AdoHcyase_NAD,AlaDh_PNT_C,DpaA_N
HALNLLBL_01816	1341157.RF007C_03440	2.42e-106	317.0	COG0583@1|root,COG0583@2|Bacteria,1TSNI@1239|Firmicutes,249QS@186801|Clostridia,3WIYC@541000|Ruminococcaceae	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
HALNLLBL_01817	1392487.JIAD01000001_gene299	2.52e-152	440.0	COG2855@1|root,COG2855@2|Bacteria,1TQYA@1239|Firmicutes,247X6@186801|Clostridia,25V2Q@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	yeiH	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
HALNLLBL_01818	483218.BACPEC_02714	1.02e-169	476.0	COG1028@1|root,COG1028@2|Bacteria,1TRYD@1239|Firmicutes,248RG@186801|Clostridia,267M6@186813|unclassified Clostridiales	186801|Clostridia	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
HALNLLBL_01825	1235799.C818_02530	5.54e-251	697.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,27J6E@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Sodium:neurotransmitter symporter family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
HALNLLBL_01826	553973.CLOHYLEM_05329	4.19e-33	120.0	COG1340@1|root,COG1340@2|Bacteria,1V7S0@1239|Firmicutes,24KZW@186801|Clostridia	186801|Clostridia	S	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
HALNLLBL_01827	1265507.KB899636_gene2543	1.48e-39	144.0	COG5551@1|root,COG5551@2|Bacteria	2|Bacteria	S	defense response to virus	cas6	-	-	ko:K19091	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	CRISPR_Cas6
HALNLLBL_01828	97138.C820_00069	7.09e-267	765.0	COG1353@1|root,COG1353@2|Bacteria,1TRW5@1239|Firmicutes,24BI3@186801|Clostridia,36JS4@31979|Clostridiaceae	186801|Clostridia	S	CRISPR-associated protein, Csm1 family	csm1	-	-	ko:K07016	-	-	-	-	ko00000,ko02048	-	-	-	HD
HALNLLBL_01829	1265507.KB899636_gene2547	3.34e-33	122.0	COG1421@1|root,COG1421@2|Bacteria	2|Bacteria	L	Csm2 Type III-A	csm2	-	-	ko:K19138	-	-	-	-	ko00000,ko02048	-	-	-	Csm2_III-A
HALNLLBL_01830	97138.C820_00067	7.85e-72	224.0	COG1337@1|root,COG1337@2|Bacteria,1V3DM@1239|Firmicutes,24IQD@186801|Clostridia,36JR3@31979|Clostridiaceae	186801|Clostridia	L	RAMP superfamily	csm3	-	-	ko:K09002	-	-	-	-	ko00000,ko02048	-	-	-	RAMPs
HALNLLBL_01831	457412.RSAG_00270	2.64e-65	214.0	COG1567@1|root,COG1567@2|Bacteria,1V4UZ@1239|Firmicutes,24IT6@186801|Clostridia,3WPNR@541000|Ruminococcaceae	186801|Clostridia	L	CRISPR-associated RAMP protein, Csm4 family	csm4	-	-	ko:K19139	-	-	-	-	ko00000,ko02048	-	-	-	RAMPs
HALNLLBL_01832	97138.C820_00065	9.13e-59	201.0	COG1332@1|root,COG1332@2|Bacteria,1V8JA@1239|Firmicutes,24IAY@186801|Clostridia	186801|Clostridia	L	CRISPR-associated RAMP protein, Csm5 family	csm5	-	-	ko:K19140	-	-	-	-	ko00000,ko02048	-	-	-	RAMPs
HALNLLBL_01833	679200.HMPREF9333_00225	5.44e-83	270.0	28K2E@1|root,2Z9RR@2|Bacteria,1TRJ6@1239|Firmicutes,24F8S@186801|Clostridia	186801|Clostridia	S	CRISPR-associated protein (Cas_Csm6)	-	-	-	-	-	-	-	-	-	-	-	-	Cas_Csm6
HALNLLBL_01834	1235793.C809_04026	9.15e-80	243.0	COG1180@1|root,COG1180@2|Bacteria,1UK6G@1239|Firmicutes,25FMZ@186801|Clostridia,27UKC@186928|unclassified Lachnospiraceae	186801|Clostridia	O	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM
HALNLLBL_01835	1341157.RF007C_09930	6.14e-33	122.0	COG4720@1|root,COG4720@2|Bacteria,1VF2R@1239|Firmicutes,24QR3@186801|Clostridia,3WMJA@541000|Ruminococcaceae	186801|Clostridia	S	ECF-type riboflavin transporter, S component	-	-	-	-	-	-	-	-	-	-	-	-	ECF-ribofla_trS
HALNLLBL_01836	1232453.BAIF02000002_gene1241	8.55e-94	286.0	COG2240@1|root,COG2240@2|Bacteria,1TRCR@1239|Firmicutes,24ABV@186801|Clostridia,267IY@186813|unclassified Clostridiales	186801|Clostridia	H	Phosphomethylpyrimidine kinase	-	-	2.7.1.35	ko:K00868	ko00750,ko01100,map00750,map01100	-	R00174,R01909,R02493	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	Phos_pyr_kin
HALNLLBL_01837	2754.EH55_04840	6.32e-10	55.8	COG2161@1|root,COG2161@2|Bacteria	2|Bacteria	D	toxin-antitoxin pair type II binding	-	-	2.3.1.15	ko:K08591,ko:K19159	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004,ko02048	-	-	-	PhdYeFM_antitox
HALNLLBL_01839	1297617.JPJD01000025_gene1128	1.4e-77	237.0	COG0503@1|root,COG0503@2|Bacteria,1V1DU@1239|Firmicutes,249VC@186801|Clostridia,268BX@186813|unclassified Clostridiales	186801|Clostridia	F	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis	xpt	-	2.4.2.22	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01229,R02142	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
HALNLLBL_01840	428125.CLOLEP_02052	3.46e-194	558.0	COG0591@1|root,COG0591@2|Bacteria,1TPVE@1239|Firmicutes,248NQ@186801|Clostridia,3WGAA@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	putP	-	-	ko:K03307,ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21,2.A.21.2	-	-	SSF
HALNLLBL_01841	1105031.HMPREF1141_0022	2.83e-135	401.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,2480T@186801|Clostridia,36ES8@31979|Clostridiaceae	186801|Clostridia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1,5.1.1.18	ko:K01775,ko:K18348	ko00473,ko01100,ko01502,ko02020,map00473,map01100,map01502,map02020	M00652	R00401	RC00285	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	-	-	-	Acyl_transf_3,Ala_racemase_C,Ala_racemase_N
HALNLLBL_01842	428125.CLOLEP_03726	0.0	981.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia,3WGRT@541000|Ruminococcaceae	186801|Clostridia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
HALNLLBL_01843	663278.Ethha_2634	1.73e-26	103.0	COG0394@1|root,COG0394@2|Bacteria,1V6SG@1239|Firmicutes,24MMZ@186801|Clostridia,3WSE6@541000|Ruminococcaceae	186801|Clostridia	T	Low molecular weight phosphatase family	-	-	3.1.3.48,5.3.1.6	ko:K01104,ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LMWPc,LacAB_rpiB
HALNLLBL_01844	1235835.C814_00269	4.66e-41	141.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,24J9Z@186801|Clostridia,3WKHF@541000|Ruminococcaceae	186801|Clostridia	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
HALNLLBL_01845	428125.CLOLEP_03729	3.09e-178	503.0	COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,247MG@186801|Clostridia,3WGP5@541000|Ruminococcaceae	186801|Clostridia	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
HALNLLBL_01846	585394.RHOM_11680	2.69e-105	305.0	COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,247XN@186801|Clostridia	186801|Clostridia	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
HALNLLBL_01847	1410674.JNKU01000031_gene905	1.13e-174	494.0	COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,4H9U5@91061|Bacilli,3F3YF@33958|Lactobacillaceae	91061|Bacilli	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,GDP_Man_Dehyd
HALNLLBL_01852	411463.EUBVEN_02778	3.8e-131	381.0	COG1242@1|root,COG1242@2|Bacteria,1TQ57@1239|Firmicutes,247U3@186801|Clostridia,25V7W@186806|Eubacteriaceae	186801|Clostridia	S	radical SAM protein, TIGR01212 family	ytqA	-	-	ko:K07139	-	-	-	-	ko00000	-	-	-	Radical_SAM,Radical_SAM_C
HALNLLBL_01854	1120746.CCNL01000011_gene1719	2.41e-65	208.0	COG5011@1|root,COG5011@2|Bacteria	2|Bacteria	C	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344,Radical_SAM
HALNLLBL_01855	1120746.CCNL01000011_gene1718	0.0	910.0	COG1032@1|root,COG1032@2|Bacteria,2NNKI@2323|unclassified Bacteria	2|Bacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344,Radical_SAM
HALNLLBL_01856	489825.LYNGBM3L_56700	0.000237	48.5	COG1994@1|root,COG1994@2|Bacteria,1G05Y@1117|Cyanobacteria,1H8MI@1150|Oscillatoriales	1117|Cyanobacteria	S	Belongs to the peptidase M50B family	-	-	-	ko:K06402	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CBS,Peptidase_M50,Peptidase_M50B
HALNLLBL_01858	1280692.AUJL01000004_gene673	5.5e-159	464.0	COG0534@1|root,COG0534@2|Bacteria,1TP5P@1239|Firmicutes,247PQ@186801|Clostridia,36VMU@31979|Clostridiaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HALNLLBL_01859	1304866.K413DRAFT_1842	4.46e-23	96.3	COG5652@1|root,COG5652@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	VanZ
HALNLLBL_01860	411463.EUBVEN_02321	1.12e-70	217.0	COG2426@1|root,COG2426@2|Bacteria,1V3UW@1239|Firmicutes,24HSW@186801|Clostridia,25WA3@186806|Eubacteriaceae	186801|Clostridia	S	small multi-drug export protein	-	-	-	-	-	-	-	-	-	-	-	-	Sm_multidrug_ex
HALNLLBL_01861	86416.Clopa_4831	2.82e-88	280.0	COG2081@1|root,COG2081@2|Bacteria,1TR7U@1239|Firmicutes,2497W@186801|Clostridia,36EA5@31979|Clostridiaceae	186801|Clostridia	S	HI0933 family	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
HALNLLBL_01862	500633.CLOHIR_00722	8.63e-200	574.0	COG2509@1|root,COG2509@2|Bacteria,1TPBW@1239|Firmicutes,247TR@186801|Clostridia,25QFR@186804|Peptostreptococcaceae	186801|Clostridia	S	'oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	HI0933_like,NAD_binding_8,Pyr_redox_2
HALNLLBL_01865	428125.CLOLEP_01160	9.91e-73	239.0	COG3583@1|root,COG3584@1|root,COG3583@2|Bacteria,COG3584@2|Bacteria,1TTIK@1239|Firmicutes,24997@186801|Clostridia,3WJ9D@541000|Ruminococcaceae	186801|Clostridia	S	G5 domain	yabE	-	-	-	-	-	-	-	-	-	-	-	3D,DUF348,G5
HALNLLBL_01867	1034769.KB910518_gene974	2.81e-48	168.0	COG2207@1|root,COG2207@2|Bacteria,1UZ0Q@1239|Firmicutes,4I2JQ@91061|Bacilli,26UQK@186822|Paenibacillaceae	91061|Bacilli	K	AraC family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
HALNLLBL_01868	1410658.JHWI01000013_gene803	2.63e-19	92.4	COG2207@1|root,COG2207@2|Bacteria,1V27P@1239|Firmicutes,3VUDX@526524|Erysipelotrichia	526524|Erysipelotrichia	K	COG COG2207 AraC-type DNA-binding domain-containing proteins	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
HALNLLBL_01869	877415.JNJQ01000074_gene71	4.67e-11	71.6	COG5279@1|root,COG5492@1|root,COG5279@2|Bacteria,COG5492@2|Bacteria,1UN60@1239|Firmicutes,3VTP9@526524|Erysipelotrichia	1239|Firmicutes	N	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,LRR_5
HALNLLBL_01870	656519.Halsa_1450	1.65e-31	122.0	COG0664@1|root,COG0664@2|Bacteria,1TVBM@1239|Firmicutes,25CKA@186801|Clostridia,3WB16@53433|Halanaerobiales	186801|Clostridia	K	PFAM Bacterial regulatory proteins, crp family	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
HALNLLBL_01871	428125.CLOLEP_00224	1.16e-250	694.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,2484F@186801|Clostridia,3WG9G@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35,4.2.1.85	ko:K01703,ko:K20452	ko00290,ko00660,ko00760,ko00966,ko01100,ko01110,ko01120,ko01210,ko01230,map00290,map00660,map00760,map00966,map01100,map01110,map01120,map01210,map01230	M00432,M00535	R03069,R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00843,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS04465	Aconitase
HALNLLBL_01872	1105031.HMPREF1141_3175	2.94e-94	276.0	COG0066@1|root,COG0066@2|Bacteria,1V1I6@1239|Firmicutes,24FUI@186801|Clostridia,36I0J@31979|Clostridiaceae	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35,4.2.1.85	ko:K01704,ko:K20453	ko00290,ko00660,ko00760,ko01100,ko01110,ko01120,ko01210,ko01230,map00290,map00660,map00760,map01100,map01110,map01120,map01210,map01230	M00432,M00535	R03069,R03896,R03898,R03968,R04001,R10170	RC00843,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
HALNLLBL_01873	1160721.RBI_I00433	4e-17	94.7	COG3209@1|root,COG3942@1|root,COG4733@1|root,COG3209@2|Bacteria,COG3942@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	cbpD	-	3.2.1.96,3.4.17.14,3.5.1.28,3.5.1.78,6.3.1.8	ko:K01227,ko:K01447,ko:K01460,ko:K07260,ko:K07451,ko:K21471,ko:K22409	ko00480,ko00511,ko00550,ko01100,ko01502,ko02020,map00480,map00511,map00550,map01100,map01502,map02020	M00651	R01917,R01918,R04112	RC00064,RC00090,RC00096,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02048	-	CBM50	-	CHAP,LysM
HALNLLBL_01875	411490.ANACAC_00591	3.48e-29	134.0	COG3209@1|root,COG3210@1|root,COG5263@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,COG5263@2|Bacteria,1V6R1@1239|Firmicutes,24K56@186801|Clostridia	186801|Clostridia	U	Leucine rich repeats (6 copies)	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
HALNLLBL_01879	1160721.RBI_I00589	1.33e-67	234.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Collagen,LRR_5,YadA_anchor
HALNLLBL_01880	1160721.RBI_I00590	1.65e-125	358.0	COG1309@1|root,COG1309@2|Bacteria,1VE7E@1239|Firmicutes,24Q2X@186801|Clostridia,3WQE9@541000|Ruminococcaceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HALNLLBL_01881	658086.HMPREF0994_06805	1.33e-169	485.0	COG5002@1|root,COG5002@2|Bacteria,1TPSK@1239|Firmicutes,25FJK@186801|Clostridia	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
HALNLLBL_01882	658086.HMPREF0994_06806	4.7e-125	360.0	COG0745@1|root,COG0745@2|Bacteria,1TSRR@1239|Firmicutes,24AG3@186801|Clostridia,27M23@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Transcriptional regulatory protein, C terminal	cutR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HALNLLBL_01883	718252.FP2_23730	2.48e-165	469.0	COG0348@1|root,COG0348@2|Bacteria,1TPHF@1239|Firmicutes,247KH@186801|Clostridia,3WI0F@541000|Ruminococcaceae	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5
HALNLLBL_01884	411483.FAEPRAA2165_01779	2.3e-125	368.0	COG0526@1|root,COG0526@2|Bacteria,1UY9A@1239|Firmicutes,24C03@186801|Clostridia,3WIRP@541000|Ruminococcaceae	186801|Clostridia	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
HALNLLBL_01887	1410670.JHXF01000010_gene522	2.15e-145	422.0	COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,2496D@186801|Clostridia,3WG83@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N,PyrI_C
HALNLLBL_01888	1410630.JNKP01000001_gene1813	1.5e-05	52.0	COG3247@1|root,COG3247@2|Bacteria,1VFKP@1239|Firmicutes,24RBX@186801|Clostridia,27NK8@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
HALNLLBL_01889	428125.CLOLEP_03304	6.5e-290	853.0	COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,248ZF@186801|Clostridia,3WGE1@541000|Ruminococcaceae	186801|Clostridia	L	ATP-dependent helicase nuclease subunit A	addA	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
HALNLLBL_01890	428125.CLOLEP_03305	1.77e-250	747.0	COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,2487T@186801|Clostridia,3WG8U@541000|Ruminococcaceae	186801|Clostridia	L	ATP-dependent helicase deoxyribonuclease subunit B	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
HALNLLBL_01891	1507.HMPREF0262_00390	5.21e-257	713.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,36E1P@31979|Clostridiaceae	186801|Clostridia	C	glutamate synthase (NADPH), homotetrameric	gltA	-	1.17.1.9,1.4.1.13,1.4.1.14	ko:K00123,ko:K00266	ko00250,ko00630,ko00680,ko00910,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00250,map00630,map00680,map00910,map01100,map01110,map01120,map01130,map01200,map01230	-	R00093,R00114,R00248,R00519	RC00006,RC00010,RC02796,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
HALNLLBL_01892	1392493.JIAB01000001_gene1271	2.55e-156	443.0	COG0543@1|root,COG0543@2|Bacteria,1TP6D@1239|Firmicutes,247YB@186801|Clostridia,27IU1@186928|unclassified Lachnospiraceae	186801|Clostridia	CH	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B	nfnA	-	1.18.1.2,1.19.1.1	ko:K00528,ko:K16951	ko00920,ko01120,map00920,map01120	-	R00858,R10146,R10159	RC00065	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
HALNLLBL_01893	665956.HMPREF1032_02832	4.81e-145	418.0	COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,248DH@186801|Clostridia,3WH12@541000|Ruminococcaceae	186801|Clostridia	C	Belongs to the LDH MDH superfamily. LDH family	ldh	-	1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	-	R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
HALNLLBL_01894	478749.BRYFOR_05754	4.24e-80	244.0	COG1971@1|root,COG1971@2|Bacteria,1V4QK@1239|Firmicutes,24FY0@186801|Clostridia	186801|Clostridia	P	Probably functions as a manganese efflux pump	mntP	-	-	-	-	-	-	-	-	-	-	-	Mntp
HALNLLBL_01895	742765.HMPREF9457_02977	5.38e-27	110.0	COG0664@1|root,COG0664@2|Bacteria,1TSP9@1239|Firmicutes,24FRD@186801|Clostridia,27WBF@189330|Dorea	186801|Clostridia	K	COG COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
HALNLLBL_01897	397288.C806_04796	2.11e-59	186.0	2C5R4@1|root,2ZC1N@2|Bacteria,1V5QY@1239|Firmicutes,24JU0@186801|Clostridia,27N4Y@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
HALNLLBL_01898	428125.CLOLEP_03219	3.62e-185	525.0	COG3206@1|root,COG3206@2|Bacteria,1TR5K@1239|Firmicutes,24ARC@186801|Clostridia,3WHRE@541000|Ruminococcaceae	186801|Clostridia	M	plasmid recombination	-	-	-	-	-	-	-	-	-	-	-	-	Mob_Pre
HALNLLBL_01899	411460.RUMTOR_02162	8.18e-187	529.0	COG3598@1|root,COG3598@2|Bacteria,1TU5N@1239|Firmicutes,247KK@186801|Clostridia,3Y28V@572511|Blautia	186801|Clostridia	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_25,PriCT_1,Prim-Pol
HALNLLBL_01900	1121115.AXVN01000075_gene2095	2.63e-51	164.0	2AQJ5@1|root,31FRY@2|Bacteria,1V6TG@1239|Firmicutes,25MZ5@186801|Clostridia,3Y0P8@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01901	428125.CLOLEP_03222	2.22e-237	655.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,3WHJS@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
HALNLLBL_01902	428125.CLOLEP_03223	2.52e-31	110.0	2E5UB@1|root,331IU@2|Bacteria,1VH5Y@1239|Firmicutes,24S88@186801|Clostridia,3WKFA@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Mga
HALNLLBL_01903	445971.ANASTE_00447	1.9e-150	442.0	COG0569@1|root,COG0569@2|Bacteria,1TPNS@1239|Firmicutes,24830@186801|Clostridia,25V3H@186806|Eubacteriaceae	186801|Clostridia	P	Potassium transporter peripheral membrane component	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
HALNLLBL_01904	1160721.RBI_I00829	7.2e-190	545.0	COG0168@1|root,COG0168@2|Bacteria,1TPAF@1239|Firmicutes,248K4@186801|Clostridia,3WGU8@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
HALNLLBL_01905	203119.Cthe_0424	2.09e-119	347.0	COG0510@1|root,COG0510@2|Bacteria,1TQW6@1239|Firmicutes,248A0@186801|Clostridia,3WGQI@541000|Ruminococcaceae	186801|Clostridia	M	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
HALNLLBL_01906	457412.RSAG_02624	1.75e-47	158.0	COG3476@1|root,COG3476@2|Bacteria,1V896@1239|Firmicutes,24MTF@186801|Clostridia,3WKUD@541000|Ruminococcaceae	186801|Clostridia	T	TspO MBR family protein	-	-	-	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	-	-	-	ko00000,ko00001,ko02000	9.A.24	-	-	TspO_MBR
HALNLLBL_01907	1507.HMPREF0262_00031	3.16e-90	270.0	2DZPR@1|root,32VFM@2|Bacteria,1VC7J@1239|Firmicutes,24NY3@186801|Clostridia,36SM5@31979|Clostridiaceae	186801|Clostridia	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
HALNLLBL_01909	428125.CLOLEP_03840	4.52e-236	656.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247VU@186801|Clostridia,3WIAF@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase
HALNLLBL_01910	1507.HMPREF0262_00054	8.27e-149	427.0	COG1475@1|root,COG1475@2|Bacteria,1TR7C@1239|Firmicutes,247TW@186801|Clostridia,36HAM@31979|Clostridiaceae	186801|Clostridia	K	Belongs to the ParB family	-	-	-	-	-	-	-	-	-	-	-	-	ParBc
HALNLLBL_01911	877414.ATWA01000005_gene696	4.89e-124	376.0	COG3843@1|root,COG3843@2|Bacteria,1TPRX@1239|Firmicutes,248VT@186801|Clostridia,267ZY@186813|unclassified Clostridiales	186801|Clostridia	U	Relaxase/Mobilisation nuclease domain	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
HALNLLBL_01912	1507.HMPREF0262_00052	2.67e-11	62.0	2DW4M@1|root,33YI1@2|Bacteria,1VNGI@1239|Firmicutes,25227@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HALNLLBL_01913	411489.CLOL250_01602	0.0	1794.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	3.2.1.78	ko:K01218	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	DUF4157,Haemagg_act,LRR_5,Peptidase_M64
HALNLLBL_01916	469596.HMPREF9488_02250	1.09e-126	362.0	COG2364@1|root,COG2364@2|Bacteria,1TU29@1239|Firmicutes,3VRNJ@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	YitT_membrane
HALNLLBL_01917	1410631.JHWZ01000001_gene1160	3.72e-151	443.0	COG2826@1|root,COG2826@2|Bacteria,1TQ0G@1239|Firmicutes,248WB@186801|Clostridia,27JR7@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38
## 1567 queries scanned
## Total time (seconds): 792.8871409893036
## Rate: 1.98 q/s