LOCUS       c00019_gnlPro..        23228 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HALNLLBL_19.
ACCESSION   c00019_gnlPro..
VERSION     c00019_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 02:07:33
            Original ID  :: gnl|Prokka|HALNLLBL_19
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 6532
            Orig. end    :: 29760
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23228
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[16532:19760]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13228
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..23228
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23228
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             774..1523
                     /locus_tag="ctg19_10"
                     /transl_table=11
                     /translation="MAKIEPIRLQKFIAQCGIASRRKAEELILGGHVKVNGKTAILGDK
                     VLPTDKVFVRGKRIVVPKGGNYRYIMLNKPRGFITTMNDERGRKCVAQLVENVGERVYP
                     IGRLDKDSEGMLVFTNDGDFANKVMHPKNNVYKIYRVTVRPSIDEDQLVKLETGVELDG
                     RKTAPAYVRVIHKEQGRVVLEMILHEGKNREIRRMCEAVGLEVARLKRTQIGGVKMGML
                     KQGDWRDLTEQEVKKLLANPFLNGKQL"
     CDS             1754..3067
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CT_Btheta"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg19_11"
                     /sec_met_domain="CT_Btheta (E-value: 2.7e-67, bitscore:
                     218.4, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIEKINQAKAEIAATSAYKTITAFFDADSFCEIDAFAKSGEGFA
                     EVVAGFGTVEGMPVYAFAQNSDICGGAMSKAQAAKLKKLYGLALKTGAPVVGFYDSVGG
                     RLNQGTELLAGCGDVLNAAASLSGVVPQISVVLGTCLGTNALNAASADIVIMSKDAQLS
                     LSVTGKHSDAAYNAENGIASIVCDDADKAIKAAKELILYLPSNNLTMAPQSFEEAPAED
                     GCGCVVSRTVDGNSIVKLFNDYGKEANVRFARLGGQVVGIVVTKGKELGCKSANKVAKF
                     VRFCDAFSLPVVTFVNCPGFESIKSATKASAAYAEATTVKISVVTGKAIGSGYVALAGT
                     GANADVVYALPDAVISPVNVEAAAFIMAPEVMNVATDKQAEVAQKFADENLSAYNAAQN
                     GYVDGIVEEAQLRQTLISALDMLSGKRVSTLSKKHSTI"
     CDS             3106..3471
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 65.7; E-value:
                     8.2e-21)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg19_12"
                     /sec_met_domain="Biotin_lipoyl (E-value: 4.2e-21, bitscore:
                     65.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNLRITVNGTAYDVQVEELGGSSAPAAAAPAPAAAPAPAAKPAA
                     PAGAQGSVVVKAPMPGTVVNVVVSAGQAVKAGDDLVFIEAMKMETPVKAPQDGTVATVD
                     VAKGESVDSGKVLVTLN"
     CDS             3502..4905
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PYC_OADA"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg19_13"
                     /sec_met_domain="HMGL-like (E-value: 1.4e-49, bitscore:
                     160.1, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="PYC_OADA (E-value: 1.7e-55, bitscore:
                     178.9, seeds: 434, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKKIRVTETALRDAHQSLIATRMTTEEMLPVLDKLDKIGYYSLE
                     CWGGATYDSCLRFLNEDPWDRLRTIREHCPNTKLQMLFRGQNMLGYRHYADDCVEYLVQ
                     RSIANGIDIIRIFDALNDIKNLKTAIKAANKEGGHAQVAISYTTGPVFTDEYYVEYAKR
                     IADAGADSICIKDMAALLTPTRTESLVKAIKAAVPELPLQLHTHYTSGLASMCLLKGVE
                     AGADGIDTAISPLALGTSHAPTESMVAALSGTEFDTGLDLKQFTDIRAYFMTLREKYIK
                     SGLLDPKMLATDANALIYQVPGGMLSNLLSQLKQAGKEDKLDEVLAEVPRVRKDSGYPP
                     LVTPTSQIVGTQAVFNVITGKRYSMCTNEFKGLVAGEYGTTPMPIDPEFQKKIIGDKKI
                     IKGRPADQLEPELDKLRGEIEQWIEQPEDVLSYAQFPKVALDFFEKRRNAKVGINGDKL
                     DKKNMVHPV"
     CDS             5100..6122
                     /locus_tag="ctg19_14"
                     /transl_table=11
                     /translation="MKKFLTALIAFVMCFLVVTTAFAATPDEASDSDLISDIKQAMLDT
                     YYGDEKPDFIEVRIYGTASDGGVYFDFMDSFTHWTDEVEFDIGDYTVSYPRDCPVLLYK
                     NNKVYTLSDAYETGVIDDDMLYELYIWGNLWGKMDVTPKGENSSLILRIKSEMKNTYYG
                     GKAPEYCCIKIVGSTSDGGVYFMHDEGSSLDYSIEETIGDYTYSYNHSDDVMLYKNGNV
                     YSIKDAYESGVIDDSILEELSKMNFGLESNKPNTTVPTEPTTSVATVDEPVTVPDTTSA
                     TSATKPVSTSDTATNDTPSNSQNNSGAVQTGQNSVAVILLVAMLAGCAVIFAKRRNYFK
                     "
     CDS             6319..7965
                     /locus_tag="ctg19_15"
                     /transl_table=11
                     /translation="MKKFLPIAMAAVMSMSAVAVSAVSANAVEPLNTPVQYAQVARASL
                     ATPKISKAESVYGGVKLTWNKVKGAAKYRVYYKGSKGWTKLADTTSTSYTDKKVSSGKS
                     YTYTIRCISKDGKKFTSGYDSKGKTVKYVAAPKISKIETVYDGTKITWNKVTGAEKYRV
                     YYKDRTGWNKLVDTTGTSVVDEGLYPAEYNISQGVANTIYTVRCISKDGKSYKSGYDSK
                     GKALTGYKQSVPDVINISTVSGGIKLEFNYALPENSKYRVYKKENGSWKKLAETYNQYY
                     TDKNVKAGKSYTYTVRGVSKDGKKFTTSYNPSGVTLKYKTTNKTRDDFVNYLMNHQSEW
                     LPHDYMGMRAQAGFEFVDLDFDGIPELIVQESGGTMCNVDAAIYSFKNGKLVKSKYNRN
                     DAVQNRFNFYYNKGTKKYEILGTAISAAGTANDHTYEKFQLKYDGYSVTTDYFAAYYVT
                     YPMNTPNGNYEYTYYNGADSYYFGIGNHKKISKSNYNDILRSRFANRVNAHKRSQFIYR
                     TAADTNWNNMSYSQKKQALLDSYDSFSYDKY"
     CDS             7984..9822
                     /locus_tag="ctg19_16"
                     /transl_table=11
                     /translation="MKKFLPIAMAAVMSMSAVAVSAVSANAVEPLNTPVQYAQVARASL
                     ATPKISKAESVYGGVKLTWGKVSGAAKYRVYYKGRKGWTRMVDTTSTSYIDKDVSSGRN
                     YTYTVRCISADGKSFTSGYDSKGKSVKYIAAPEISKLENVNGGVKISWGKVSGATKYRV
                     YYKGSKGWTKMVDTTSTSYTDKDVSSGRNYTYTVRCITSDAKKFTSGYNPTGKSVKYVA
                     TPKISKLEVTYDGVKLTWNKVAGAEKYRVYYKDRNGWTKLGDTTGTTMLDMNVVSKEFD
                     LSVDDIYYTVRCISKDAKSFTSGYDSKGTPIGDHQDCPEIYSIGAVNNGVEMHWTGDAP
                     KFRVYIKENGSWKKIAETYDNYYVHKGAKSGSNTYTVRGVSKDGKKFTTMFNPTGVTYR
                     YKTSDKTRDAYINYMMNHTDEWMPSLGSNHNLSGVMFLDFDFDGVPELVAQKADSKEYG
                     FHSVVYKFEDGKLKRVGNVNDGFSIYYNKTAKKYEVHDLDIYLNVDDGYYWTGNSIITY
                     DGENLFANMYSARGVGEESNNNIYYKYFDGNDKNISRAKYNEINLKQFNNCVNAHMFTE
                     FIATGYGDTSVWGEKTTTENKQSLLDAYNSFSYEKY"
     CDS             complement(10001..11041)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg19_17"
                     /sec_met_domain="IlvN (E-value: 1.1e-83, bitscore: 269.8,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 1.5e-60, bitscore: 194.7,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDYTKNMTAPIYYQSDCNLDLLKGKKIAIIGYGSQGHAHALNLR
                     DSGCDVIVGLYKGSKSWAKAEAQGFKVYTSAEAAKQADIIMILINDEKQAALYKNDIEP
                     NLEAGNMLMFAHGFNIHFGCIKPPKDVDVTMVAPKGPGHTVRSEYQVGKGVPCLVAVEQ
                     DATGQAKDLALAYALGIGGARAGVLETTFRTETETDLFGEQAVLCGGVCALMQAGFETL
                     CDAGYDPRNAYFECIHEMKLIVDLIYQSGFAGMRYSISNTAEYGDYITGPKIITEDTKK
                     AMRKVLSDIQDGTFAKDFLLDMSDAGSQVHFKAMRKLAAEAPAEVFGKEVRKLYSWSDE
                     DKLINN"
     CDS             complement(11102..11593)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg19_18"
                     /sec_met_domain="ALS_ss_C (E-value: 1.1e-29, bitscore:
                     93.7, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQYTLSILVENQAGVLSKISGLFSRRGFNIDSLAVGVTQEPSVSR
                     ITIVANGDEYIVEQLEKQLNKLIPVIKVKRLNEGEFISRELVLIKVHCAASKRAEIVKT
                     VEIMQAKIVDVSPSSVTVEYCECASRVNTLVDLLKPYGIREIVRTGTVAIDRGTASVSV
                     "
     CDS             complement(11606..13228)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg19_19"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.1e-43, bitscore:
                     138.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISGAEIMVKCLEAEGVDIVFGYPGAAICPFYDKIYDSSITHILV
                     RQEQNAAHAASGYARCSNRPGVCVATSGPGATNLITGIATAYTDSIPIVAITGQVRSDL
                     LGRDVFQEADITGACEPFVKHSYLVSKTEDLPRVFKEAFHIASTGRPGPVLIDIPVDIQ
                     ENEIESFEYPESVNIIGYKPNTKGHAIQVKKAVEAINASKRPVIVSGGGVLSSGIKLKL
                     QKFAETTGIPVISTMMGIGVMPSEHELYLGMLGTHGKAVANRALHEADLVIVCGARLGD
                     RAVAAPDQMSENTKVIHIDIDPAEIGKNVKTEIPIVGDMKNVINMLLDSIGDYKVTTMW
                     SETVKNWKKDLYREPPVFDGFVEPRTLVGHLSAMFRSKAILVADVGQNQIWCANNFRIR
                     EGRFLTTGGMGTMGYSIPAAIGAKFARPDRDVIVICGDGSFQMGLNELATIAGNQLGIK
                     IIIMKNARLGMVRELQDKHYGGRHSATILNGDPDFLKIAEAYGIDHAEAHSNKEAENII
                     KGIVDSEKPFILVCDVHPDTPSI"
     CDS             complement(13529..15625)
                     /locus_tag="ctg19_20"
                     /transl_table=11
                     /translation="MRYKYQLDNLNCAHCAGKIEAKIAETDGFEDVSFNFATKLLNFKS
                     EKQNPVSEIQAICDSIEDGVTVVDKTPKNDVTTKAEPEITKKKINHDTIFLAISIVLAV
                     VSEILHLTLDGVTAVHYVVLAACFVATLLSGYKVFIKGAKNILKLKIDETTLMAVAVIA
                     AFCLGDFVEAAMVTILFSIGEIFEDRAVDASRRDIEKLANIRPDTATIIVDGADQIVPA
                     ESVEIGSIIEVKPYERVPLDGIIIKGKTTLDTSALTGESLPVDAGEGSEVLSGAINGSN
                     LITVKTTKHFGDSTATRILQLVEDAAAQKGNSEKLISRFASVYTPVVVLIAVAIAVIPP
                     LCGLGAFSEWLYRALVCLVASCPCAIVISVPLSYYSGIGAASEVGVLIKGGKYIEALAK
                     ADTFVFDKTGTLTSGKLSVNKVNTVGSYSADEVLALAAASEKYSAHPIASAIRERANGL
                     ELPELSDYSESAGHGTSAVYNGKTIQCGGSKILSNEQKKIANKDDSVFVIYDGQLIGSL
                     NVSDTVRPEAKEVISQLKALGVKNTVMLTGDRQQPAENVKNELGLSECHAELLPAQKLE
                     LFKGLKSKSKGACFVGDGINDAPVLSASDCGIAMGFGSEAAIEASDAVLASGTLKQLPK
                     AIKIARSVINTVKGNIIFALSIKALVIILAAFGLAQIWMSVIADTGVSVVCVLIAARLL
                     KKKY"
     CDS             complement(15637..15954)
                     /locus_tag="ctg19_21"
                     /transl_table=11
                     /translation="MENKEKTTTPEMPDIDVLFELADLFKVFGDSTRLRIMYTISENEM
                     SVLNIAEALNMEQSTISHQLRVLRQNKLVRVRREGKQIYYSLDDDHVKRIIEMGLDHVL
                     E"
     CDS             16587..17879
                     /locus_tag="ctg19_22"
                     /transl_table=11
                     /translation="LEKFVVTGGKPLSGEVTISGAKNAAVAIIPAVILCDEPCQIENIP
                     NISDVSLISRILQQMGANVRRINRSSLYIDPTKIRTCNAVTDLVRGMRASYYLLGALLG
                     KYGKAKVALPGGCNFGVRPIDQHLKGFEALGATTQLVDGAIIEAECDNLVGTHVYLDVV
                     SVGATMNIMLAASKAKGQTIIENAAREPHIVDLANFLNSMGADVRGAGTDVIKIRGVEY
                     LHGITYSIIPDQIEAGTYMCAAAATRGCITVKNITPKHLESISAKLREMGVKITEYDEA
                     LKVDASSAPLKRCNIKTMPHPGFPTDCQPQFAALLMSVPGTSIINENVWDNRYQYVSEL
                     VRMGAQISVEGRLAIIEGGTPLTAAPVKATDLRAGAAMIIAALEINGTTEISNIQFIER
                     GYEDVVEKFRALGADIKKVYFTGDNEQELGA"
     CDS             18006..18794
                     /locus_tag="ctg19_23"
                     /transl_table=11
                     /translation="LARAVPLFSGSKGNSYYIGSATEGVLIDAGRSCKQIENAMLANGI
                     DMSSIGAVFITHEHTDHCSALRVLAKRYGFKVYSSLGTLNALRAGNKLDPNTDADVITD
                     EVVIGNMRVQRFDTPHDTAESCCYRVTAPDGKSALIATDMGVMLSDVRTAAEQSDFVVL
                     ESNHDINMLKNGFYPYPLKQRILSNRGHLSNEACAKELVNLVEKGTLRLMLGHLSEENN
                     TVPLAMSTSVDLLTSNGMKYKSDYSLDVAPSISTTKTIIF"
     CDS             18816..19301
                     /locus_tag="ctg19_24"
                     /transl_table=11
                     /translation="MIKINIICIGKIKEKYFTDAIAEYAKRLTAFCKFNIVELSEERIK
                     SNTPNQSQIDEVISSEGKRIMQKISPSDYVVAMCIEGKLMSSEELSKLIDNASVSGKST
                     VDFIIGGSYGLDESVKKRSDVRLSMSKMTFPHQMARMILSEQIYRAFEISSNGKYHK"
     CDS             19316..21064
                     /locus_tag="ctg19_25"
                     /transl_table=11
                     /translation="MALDGIFLRHIKNEIEKEALGARVSQIYQPNREELVFGLRTFSGN
                     KKLLLSARANSPRVNFCSSTPENPAQPPMFCMLLRKRIGGGKLVGLRQNGCDRVLMLDF
                     ECVNELGDTVMITVVCEIMGMYSNIIIVDSNGVIIDSLKRVDLTMSSKRLVLPNIKYEL
                     PESQNKLNLLECTALDVCTAVKNLDAEMPLNRALLRTIEGVSPIVCREIEYKVMEGATN
                     RIEGVLFDRLAVEIEKLKCVCSDCSGKPVVVYREDGKPMDFCFMNVEQYGDFAKVESKE
                     SFSDLLDGFYEARDSRDRMRVKSQSLTKLLNNTLERLARKIAKQQSELERCADREHLRI
                     CGDLLQANIYRIERGAEYVDVENFYDENNAILRIKLNPAISPSANAQKYYKDYRKAKNA
                     EIMLKEQLEKGREELDYIDSVLDTVDRAENEKDLSQIREELTEQGYLKIQKGKKARQTT
                     LPPLEFESSDGFKILVGRNNRQNDKLTLKTASKNDMWLHTKDIHGSHVIVVSDGKEISD
                     TAICEAAQIAAYHSKARNSSQVPVDYTLVRYVSKPNGSKPGMVIYVNNKTLYVKPSQTI
                     EKQKIQ"
ORIGIN
        1 gttttcacag cgaatgaatg aaaaggcgaa gcaaatcggt atgacgaata ccaattttgt
       61 aacgccgagc ggacttgacg atgacaacca ttactcaagt gcaaaggata tggctctgct
      121 tatgtcatac gcacttgaaa atgacgattt tgcaaatctt acggctaaga agagcgtgac
      181 cgttgaattt cttgaaccga aatcaaagaa aaccgcatat gcaaatcata acaggctttt
      241 gtcgctttat ccctactgta caggcggaaa aacaggctat acaacggcgg cagggcggtg
      301 ccttgtttcc tctgcaaaaa aagacggtgt aacgcttgtg tgcgtcactc tgaatgaccg
      361 caacgattgg aatgaccata tttctcttta tgattacgct tttgaaaagt acaggggagt
      421 tgactgcaag gacgctgact tttgtgccga tattccgtgc gtgggcggtg ataaggacag
      481 cgtaacggtt acaggcgaga agaacagcac aatcgtttta aagcgtgagg actgcgataa
      541 aatcaagaag aaaatctata tagacggctt tttgtatgct ccgattgaaa agaacgagtc
      601 ggtaggcaga attgaataca cactcggcgg aaagctgctt tataaatgca acattgttgc
      661 aggcgaaaag attaaatcgg ataaaaagag tgtgtcaata ttttcggcaa taggaaatct
      721 gttttcgtga cagcttaaat atacagaaaa ttttattaaa aaggaattta catatggcta
      781 aaattgaacc tataagactt cagaaattca tagcgcaatg cggtattgcg tcaaggcgaa
      841 aggccgagga gcttattctc ggcggtcatg tcaaggtgaa cggcaaaacc gcaattctcg
      901 gtgacaaggt tcttcctaca gacaaggtgt ttgtaagagg caagaggatt gttgtgccga
      961 agggcggcaa ttaccgatat attatgctca acaaaccccg tggattcatt accacaatga
     1021 atgatgagcg tggcagaaag tgtgttgcac agcttgttga gaatgtcggc gagcgagttt
     1081 atccgatcgg cagacttgac aaagacagcg agggtatgct tgtttttaca aatgacggtg
     1141 actttgcaaa caaggttatg cacccgaaaa acaatgttta caagatttac agagtaaccg
     1201 ttcgaccgtc aattgacgag gatcagcttg taaagcttga aacaggcgtt gagcttgacg
     1261 gcaggaaaac cgctcctgca tatgtccgtg taattcacaa ggagcagggc agagtagttc
     1321 ttgaaatgat tcttcacgag ggtaagaacc gtgaaatcag aagaatgtgc gaggctgtcg
     1381 ggcttgaggt tgcaagactc aaacgcaccc agatcggcgg tgtaaaaatg ggtatgctca
     1441 aacagggcga ctggagagat ttgaccgaac aagaggttaa aaaactgctt gcaaacccgt
     1501 ttttaaacgg caaacagctt taattttctg tttttgaaaa atacttccga aacggtgaat
     1561 aaaactattc gttaatttga caataaattt acggttttgt cgtaataact attaaatgtg
     1621 ttcaaaattg aaatagtaca gcgtgttttt cttgtacttt tgaagattat agagtataat
     1681 gtatcgtgta gaaaattagt atgcacgctc agttttcgtg catattcaat acatggtatt
     1741 ggaggatttt aagatgagta ttgaaaagat caatcaggca aaggctgaaa ttgccgcaac
     1801 ttccgcttat aagacaatta cggcgttttt tgatgcagac agcttttgtg aaattgatgc
     1861 ctttgcaaaa tccggtgaag gttttgccga ggttgttgca ggctttggaa cagtagaagg
     1921 tatgcctgtt tatgcgtttg cacagaacag cgacatttgc ggcggtgcca tgagtaaggc
     1981 acaggctgcc aagcttaaaa agctttacgg tcttgcactc aagacaggcg ctcctgttgt
     2041 aggtttctat gacagcgttg gcggcagact taatcagggt acagagcttc tcgcaggctg
     2101 cggtgatgtt ctcaatgcgg ctgcgtcact ttccggtgtt gtaccgcaga tttcggttgt
     2161 tctcggcact tgcctcggaa caaacgctct taacgccgca agcgcagaca tcgttatcat
     2221 gagcaaagac gcacagcttt cactttcggt aacaggcaag cattccgatg ccgcttacaa
     2281 tgctgaaaac ggcattgcct caatcgtttg tgacgatgca gacaaggcaa tcaaggctgc
     2341 aaaggaactt atcctttatc ttccgtcaaa taacctcaca atggctcctc agtcatttga
     2401 agaagctcct gcagaggacg gctgcggttg tgtagtcagc agaacagttg acggcaacag
     2461 cattgtaaag ctcttcaatg attacggcaa ggaagcaaat gttcgttttg caagactcgg
     2521 cggtcaggtt gtaggtattg ttgttacaaa gggcaaggag cttggttgca agtctgcaaa
     2581 caaggtagca aagtttgttc gtttctgcga tgctttctca ctccctgttg taacattcgt
     2641 aaactgcccg ggctttgagt caatcaagtc ggcaacaaag gcgtcagccg cttatgctga
     2701 ggcaacaaca gttaagattt ctgttgttac aggcaaggca atcggttcag gctatgttgc
     2761 tcttgcaggc acaggcgcta atgcagatgt tgtttacgca cttcccgatg cggttatttc
     2821 acctgttaat gttgaggctg ccgcattcat tatggctccc gaagttatga atgttgccac
     2881 agataagcag gctgaggttg ctcagaagtt tgctgacgag aatctttctg cttacaatgc
     2941 cgctcagaac ggctatgttg acggtattgt tgaagaagct cagctccgtc agactcttat
     3001 ttctgctctt gatatgctct cgggcaagcg tgtttcaaca ctttcaaaga agcattcaac
     3061 tatctgataa atgattactt gttaaaataa aaggggatac taaaaatgaa gaatttaaga
     3121 attacagtta acggcacagc atatgatgtt caggttgaag aactcggtgg ctcttcagct
     3181 cccgcagcag ccgctcctgc tcctgcagcc gctcccgctc ctgcagcaaa gccggcagct
     3241 cccgcaggcg ctcagggttc tgttgttgta aaggctccta tgcccggtac agttgttaat
     3301 gttgttgttt cggcaggaca ggctgttaag gctggagatg acctcgtatt catcgaggct
     3361 atgaagatgg aaactcccgt taaggctccg caggacggca cagttgcaac agttgatgtt
     3421 gcaaagggtg agtcagttga ctcaggtaag gttctcgtaa cacttaacta atcaataatt
     3481 cggagaaagg gatgctgtaa aatggcaaaa aaaatcagag ttaccgaaac tgctctgcgt
     3541 gacgctcatc agtcactcat tgcaacaaga atgacaacag aggaaatgct ccctgttctt
     3601 gacaaactcg ataaaatcgg ttattactca ctcgaatgct ggggcggcgc aacatatgac
     3661 tcatgcctca gattcttaaa cgaagatccg tgggacagac tccgcacaat cagagagcat
     3721 tgccctaaca caaagctcca gatgcttttc agaggacaga atatgctcgg ttatcgtcac
     3781 tatgccgatg actgcgttga gtaccttgtt cagcgttcaa tcgcaaacgg tattgacatt
     3841 atccgtattt ttgatgctct taacgacatc aagaatctta aaacagctat caaggccgct
     3901 aacaaagaag gcggtcatgc gcaggttgct atcagctaca caacaggtcc tgtattcaca
     3961 gatgaatact atgttgagta tgctaagaga attgcagacg caggtgcaga ttcaatctgt
     4021 atcaaggata tggctgctct tcttactccg acaagaaccg aaagccttgt aaaggctatc
     4081 aaagccgctg ttccggagct tccgcttcag ctccacaccc actacacatc aggtcttgca
     4141 tcaatgtgtc ttttaaaggg tgttgaggca ggtgccgacg gcattgacac agcaatcagc
     4201 ccactcgctc tcggtacatc acacgctccg acagagtcaa tggttgccgc tctttcaggc
     4261 acagagttcg acacaggtct tgaccttaaa cagttcactg acatccgtgc ttacttcatg
     4321 actctccgtg agaagtacat caagtcagga cttcttgatc ctaagatgct cgcaacagac
     4381 gctaacgctc ttatctatca ggttcccggc ggtatgcttt ccaaccttct ttcacagctc
     4441 aagcaggccg gtaaggaaga caagcttgac gaagttcttg cagaagtacc ccgtgttcgt
     4501 aaggattcag gttatcctcc gcttgttact ccgacatcac agattgtcgg cacacaggct
     4561 gtattcaatg taataacagg caagcgctac tcaatgtgca caaacgagtt caagggactt
     4621 gttgccggtg agtacggtac aactccaatg ccgattgatc ctgagtttca gaagaagatt
     4681 atcggtgaca agaagattat caaaggccgt ccagcagatc agcttgagcc tgagcttgat
     4741 aagctccgtg gcgagattga gcagtggatt gaacagcctg aagatgttct ttcttatgca
     4801 cagttcccga aggttgccct cgacttcttt gaaaagagaa gaaatgccaa ggttggcatc
     4861 aacggcgaca agcttgacaa gaaaaatatg gttcaccctg tttgatttga caacaaaaat
     4921 taacatttat gccactttcg ctatgaaagt ggcattttca tttgagcaga attattcttg
     4981 ctaaattttt agcaactata ttgcattaca tatattttag cggtataatt aagtaaattg
     5041 aatatctgtt gcgtatacca ttattacaga tagaataaat aaaaggtgag gaaataaaaa
     5101 tgaaaaaatt tttaacagca ttgatagcat ttgtaatgtg ctttttggtt gtaacaacgg
     5161 cttttgcggc tacacctgat gaagcttctg attcagactt gatttcagat attaaacagg
     5221 ctatgttaga tacatattat ggtgatgaaa agcctgattt tattgaagta agaatatatg
     5281 gtacagccag tgacggtggt gtgtatttcg attttatgga tagttttaca cactggacag
     5341 atgaagtgga attcgatata ggtgattata ctgtttctta tccgagagat tgtcccgttt
     5401 tgttatacaa gaataataaa gtatatacct tgtcagatgc ctatgaaaca ggtgtaattg
     5461 atgatgatat gctctatgaa ttatatatat ggggaaatct ttggggtaag atggatgtta
     5521 ccccaaaggg tgaaaattca tctctcattt tgcgtatcaa aagtgaaatg aaaaatacat
     5581 actatggcgg caaagctcct gaatattgtt gtattaaaat tgttggttca acgagtgacg
     5641 gtggagtata ttttatgcac gatgaaggca gtagtcttga ctattcaatt gaagaaacaa
     5701 ttggtgacta tacttatagt tacaaccata gtgatgatgt tatgctttat aagaatggca
     5761 atgtttactc aatcaaagat gcttatgaaa gcggagttat tgacgatagt attcttgaag
     5821 aattgtcaaa gatgaatttt ggtttggaat ctaataaacc gaatacaact gtacctactg
     5881 agcctacaac ttcggttgca acagttgacg aacctgtaac agtacctgat acaacttctg
     5941 caacttctgc aacaaagcct gtttcaacaa gcgacacagc aacaaatgac acaccgagca
     6001 attcacagaa taacagcggt gctgtacaga caggacagaa cagcgttgct gtaattcttc
     6061 ttgttgcaat gcttgctggc tgtgcagtaa tttttgcaaa acgcagaaat tattttaaat
     6121 aattcaaaac atcaacagaa tatataaaat aaaccgttct cgcttttgtg aacggtttat
     6181 ttattttagc ttaaaaattt gtgatagttt atcaagatgt attgcttttt atatcattta
     6241 atgttacaat taacttgcat aaaaatacag cgaaagtttt taataatgcg tagaatattt
     6301 acaaagcgag ggatagatat gaaaaagttt ttacctatag ccatggcggc ggtaatgtcg
     6361 atgtctgcgg ttgcggtttc ggctgtttct gcaaatgcgg ttgaaccgct gaacacaccc
     6421 gtgcagtatg cacaggttgc aagggcaagc ttggcaactc cgaaaatttc aaaggctgaa
     6481 agcgtttacg gcggtgtaaa gcttacatgg aacaaagtta agggcgcggc taaatacaga
     6541 gtttactaca agggcagtaa aggctggact aaacttgccg acacaacctc aacctcatat
     6601 accgacaaaa aggtttcatc aggcaaaagc tatacataca caatcagatg tatcagcaag
     6661 gacggcaaaa agtttacaag cggatatgat tcaaagggca aaacagtaaa atatgttgcc
     6721 gctccaaaaa tttctaagat tgaaactgta tatgacggca ccaaaattac atggaataaa
     6781 gttacaggtg cagagaagta tcgtgtgtat tataaagaca gaacaggttg gaataaactt
     6841 gttgacacaa caggtacaag tgttgttgat gagggattat atcctgcaga atataatatt
     6901 tctcaaggtg ttgctaatac gatatatact gtccgttgta taagtaaaga cggcaagagt
     6961 tataaaagtg gatatgattc caaagggaaa gcattaacag gttataagca atcagttccg
     7021 gatgtaatta atatatcaac cgttagtggc ggtataaaac ttgagtttaa ttatgcttta
     7081 cctgaaaact caaaataccg tgtgtataaa aaagaaaacg gctcttggaa gaaacttgct
     7141 gaaacttaca atcaatacta tacagataaa aatgttaaag ccggcaaaag ctatacttat
     7201 acagtaagag gtgtatctaa ggacggtaaa aagttcacaa cttcctataa cccgtcaggt
     7261 gtgacattaa agtataagac aactaataaa acaagagatg attttgttaa ttatcttatg
     7321 aatcatcaga gtgaatggtt acctcatgat tatatgggta tgagagcaca ggctggattt
     7381 gaatttgttg atcttgactt tgatggcatt cctgaactca ttgtacagga atccggtgga
     7441 acgatgtgca atgtagatgc agcaatttat tcgtttaaga acggtaaact tgtaaagtcg
     7501 aaatataata gaaatgatgc agtacaaaac agatttaatt tttattataa taaaggcact
     7561 aaaaaatatg agatacttgg cactgctatt tcagcagcag gaacagccaa tgatcataca
     7621 tacgaaaaat ttcagctcaa atatgacggt tattctgtaa ctacagatta ttttgctgca
     7681 tactatgtga cttatccaat gaatactcca aatggaaatt atgaatatac atattataac
     7741 ggtgctgata gttattattt tggtatagga aatcataaga aaatttcaaa atcaaattac
     7801 aatgatatat taagaagcag atttgcaaat cgtgtaaatg cacataaacg cagtcaattt
     7861 atttatcgta cagctgccga cacaaactgg aacaatatgt catattctca gaaaaaacag
     7921 gcattgcttg attcatacga ttcattctcg tatgataaat actaattaaa gcgagggata
     7981 gatatgaaaa agtttttacc tatagctatg gcggcggtta tgtcgatgtc tgcggttgcg
     8041 gtttcggcag tttctgcaaa tgcggttgaa ccgcttaaca cacctgtgca gtatgcacag
     8101 gttgcaaggg caagcttggc tactccgaaa atttcaaaag ccgaaagcgt ttacggcggt
     8161 gtaaaactga cttggggcaa ggtaagcggt gcggctaaat acagagttta ctacaagggc
     8221 cgtaaaggtt ggacacgaat ggttgataca acttcaacct catatatcga caaggatgtt
     8281 tcatcgggca ggaattacac ctatactgta agatgtattt ctgctgacgg aaagagcttt
     8341 acaagcggtt atgattcaaa gggcaaaagt gtaaaatata ttgccgcccc cgaaatttca
     8401 aagcttgaaa atgtaaacgg cggtgtgaaa atctcttggg gcaaagtaag cggtgcgact
     8461 aaatacagag tttactacaa gggcagtaag ggctggacaa aaatggttga tacaacttca
     8521 acctcatata ccgacaagga tgtttcatcg ggcagaaatt acacttatac tgtaagatgt
     8581 attacatcag acgcaaagaa atttacaagc ggttataacc cgacaggcaa gtcggtaaag
     8641 tatgtagcca caccgaaaat ttcaaaactt gaggttacat atgacggtgt aaagctgaca
     8701 tggaacaagg tcgcaggtgc agaaaaatac cgtgtgtact acaaggacag gaacggttgg
     8761 acaaagcttg gcgacacaac aggcacgact atgcttgata tgaatgttgt ttcaaaggaa
     8821 tttgatttaa gcgttgacga tatttattac acggttcgct gtatcagcaa ggatgccaag
     8881 agttttacaa gcggatacga ttcaaagggt acgcccattg gcgatcatca ggattgtccc
     8941 gaaatttaca gcattggtgc agtaaacaac ggtgttgaaa tgcattggac gggagatgcg
     9001 ccaaagttcc gtgtttatat taaagaaaac ggttcttgga agaagatagc agaaacttat
     9061 gacaactatt atgttcacaa gggtgcaaag tccggcagta acacttatac ggtaagaggt
     9121 gtttcaaaag acggtaaaaa gtttactacg atgtttaacc caaccggtgt aacatacaga
     9181 tataagacat ccgataaaac aagggacgct tatatcaatt atatgatgaa tcataccgat
     9241 gaatggatgc caagcttggg aagtaatcac aatttgtcag gtgttatgtt tttggatttc
     9301 gactttgacg gagttccgga gcttgttgca caaaaggctg attccaaaga gtatggtttc
     9361 cattccgttg tttacaaatt tgaagacggt aagttaaaaa gagtgggaaa tgttaacgac
     9421 ggtttttcga tatactataa taaaactgcc aaaaagtatg aggttcacga cctggatata
     9481 tatttaaatg tagatgacgg ttactattgg acgggtaatt caataatcac atacgacgga
     9541 gagaatcttt ttgcaaatat gtattcggca agaggcgtag gcgaagaatc aaataataat
     9601 atttattata aatattttga cggtaatgac aaaaatattt cacgggcaaa atataacgaa
     9661 attaacctta agcagtttaa taattgcgta aatgcacata tgtttaccga atttattgcg
     9721 acaggttatg gtgataccag cgtatggggt gagaaaacta ccactgagaa taagcagtct
     9781 ttgcttgacg cttataattc tttctcctat gagaagtatt gattatttaa aaattaataa
     9841 gttttaactg caaaagggtt cagccgtaaa aaactgaacc cttttattgc acaacaaaaa
     9901 aacggttcag ccaaattgac tgaaccgtta atttatacta tgtaacgctc gggtgacaga
     9961 agcttgaata tatcaaactg tcttcacaaa ctaaaaaaca ttagttgttg atgagcttat
    10021 cttcgtcaga ccagctgtag agctttctaa cttccttacc gaatacttcg gcaggagctt
    10081 cggcagcgag ctttctcata gccttgaagt gaacctgtga acctgcatcg ctcatgtcaa
    10141 ggaggaagtc cttagcaaat gtaccgtcct gaatgtcaga aagaaccttt ctcatagcct
    10201 tcttagtatc ctctgtgatg atctttggac ctgtgatgta gtcaccgtac tcagctgtgt
    10261 tagagattga atatctcatg cctgcaaaac ctgactgata gataaggtca acgatgagct
    10321 tcatctcatg gatacactca aagtaagcat ttcttgggtc gtaaccggca tcgcaaagtg
    10381 tttcaaaacc tgcctgcata agtgcgcaaa caccgccgca aagaacagcc tgctcaccga
    10441 agaggtctgt ttctgtttct gttctgaatg ttgtttcaag aacgccggct cttgcaccgc
    10501 cgataccgag tgcatatgca agtgcgagat ccttagcctg acctgtagca tcctgctcaa
    10561 cagcaacgag gcaaggtaca cccttaccaa cctgatactc tgaacgaact gtgtgacccg
    10621 gtcccttagg agctaccatt gtaacatcaa catcctttgg aggcttgatg caaccgaagt
    10681 gaatgttaaa gccgtgagcg aacataagca tattgcctgc ttcgaggttt ggctcgatgt
    10741 cgttcttgta aagagctgcc tgcttttcat cgttgataag aatcatgatg atgtcagcct
    10801 gctttgcagc ctctgccgat gtatatacct taaagccctg tgcttcagcc tttgcccagc
    10861 tcttgctgcc tttgtaaaga ccgacgatta catcgcaacc tgaatccctg aggttgagag
    10921 cgtgtgcatg accctggctg ccgtaaccga taatagcaat tttcttaccc ttgagaaggt
    10981 caaggttgca atctgactga tagtagattg gtgctgtcat gttttttgtg tagtctttca
    11041 tattaaagtc ctccttaccg caaacgcggc atataaatta aaatatatgc taactgtaag
    11101 attaaacgga aaccgaagct gtgcctctgt caatggcaac agtacctgtt cttacaatct
    11161 cacggatacc ataaggcttg agtaagtcaa caagcgtgtt gacgcggctt gcacattcgc
    11221 agtactcaac ggtaactgac gaaggggata catcaacgat tttcgcctgc ataatttcaa
    11281 ccgttttgac aatttcggct ctttttgagg cggcgcagtg aaccttgatt aaaacaagct
    11341 cacggctgat aaattcgccc tcgttaagcc tttttacctt gatgacggga atgagcttgt
    11401 ttagctgttt ttcaagctgt tcaacaatgt actcgtcacc gtttgcaacg attgtgattc
    11461 gggaaaccga cggttcctga gtaacaccta ctgcgagtga gtcgatgtta aaacctcggc
    11521 gagagaaaag tcccgaaatc tttgaaagaa cgcccgcctg attttcaaca agtattgata
    11581 atgtatactg cattttatca cctcattaaa ttgacggagt gtcggggtga acatcgcaaa
    11641 caagaatgaa cggtttttcc gaatcaacaa tacccttgat gatgttttcg gcttccttgt
    11701 ttgaatgagc ctctgcatgg tcaatgccgt aagcctcggc aatcttcaag aagtcgggat
    11761 caccgttgag aattgttgcg gagtgtctgc cgccgtagtg tttgtcctga agttcacgaa
    11821 ccattccgag tcgtgcgttt ttcataatga tgattttaat tccgagctga ttgcctgcaa
    11881 tagtcgcaag ctcattaagc cccatctgaa aactgccgtc accgcagatt acaataacat
    11941 cacggtcggg tcttgcaaac tttgcaccga ttgcagcggg aatcgagtaa cccattgtac
    12001 ccataccgcc tgttgtgagg aatctgccct cacgaatacg gaagttattt gcacaccaga
    12061 tttgattttg tcctacatcg gcaacgagaa ttgcctttga gcggaacatt gcactgagat
    12121 gaccgacaag tgttctcggc tcaacaaagc cgtcaaatac gggaggctca cggtaaaggt
    12181 cttttttcca gttctttacg gtttcgctcc acattgttgt aaccttgtaa tcgccgatgc
    12241 tgtcaagcag catattgatg acatttttca tatcgcctac aatcggaatt tctgttttaa
    12301 cattcttacc gatttcagca gggtcaatgt caatgtgaat tacctttgtg ttttcactca
    12361 tctggtcggg agccgcaaca gctctgtcgc cgagtcttgc accgcatacg attacaaggt
    12421 cggcttcgtg aagagcacgg ttggcaacag ccttgccgtg agtgccgagc attccgagat
    12481 aaagctcatg ctcgctgggc ataacaccga tgcccatcat agttgaaata acggggatac
    12541 ccgtagtttc tgcaaatttt tgaagtttaa gcttgatacc cgaactcagc acgccgccgc
    12601 ctgatacgat aacaggacgc ttgcttgcgt tgatggcctc aacagccttt ttaacctgaa
    12661 ttgcgtgtcc cttagtgttc ggtttgtaac cgataatgtt tacgctttcg ggatattcaa
    12721 aactttcaat ttcattttcc tgaatatcaa cgggaatgtc gataagtaca ggaccgggtc
    12781 tgccggttga ggcaatatgg aaagcctctt tgaaaactct cggaaggtct tctgttttgc
    12841 tgacgagata actgtgcttt acaaacggtt cacaagctcc cgtgatgtca gcttcctgaa
    12901 agacatctct gccgagaagg tcggaacgaa cctgacctgt aatggcaaca atcggaatag
    12961 agtccgtata ggcggttgca atgcctgtga tgaggttggt tgcaccggga ccggaagttg
    13021 ccacgcaaac accgggacga ttactgcatc ttgcatagcc gcttgccgca tgagcagcgt
    13081 tctgttcctg acgaacaaga atgtgggtaa tgctcgaatc gtaaatttta tcgtaaaatg
    13141 ggcagatagc cgcaccggga taaccaaaga ctatgtcaac gccctcggct tccaaacatt
    13201 ttaccataat ttcagcaccg ctgatcatta tgttttgtcc ctcctatcct ttttattgtg
    13261 agcaaaaggt gttttgtaac attaaatata cccttttact ttaccgctaa ttatacaata
    13321 aataccttaa aaagtaaaga gcagtattgc ccataaatta aattttttgc aggattttaa
    13381 attattctgt catcgcctga aaaagatata ataaatgatt aacaacaaaa acaaaatgct
    13441 gaccaaaaaa gtatctgtat aagagtaata acaagaaaat tcccgaacag ttttacctgc
    13501 tcgggaacag taatgattgt tgagaaaatc aatatttctt tttgaggagt cttgcggcta
    13561 tgaggacgca gactacgctg acgcctgtgt cggcgataac ggacatccag atttgtgcaa
    13621 gaccgaatgc ggcaaggata attacaagag ccttgattga gagggcaaag atgatgttgc
    13681 ccttgacggt gttgataaca cttcttgcaa ttttaattgc ctttggaagc tgtttgagtg
    13741 tgcctgatgc gagaactgcg tctgacgctt caatagcggc ttcactgccg aatcccattg
    13801 cgataccgca gtcgcttgcc gaaagaacag gggcatcatt gatgccgtcg cccacaaagc
    13861 aagcaccctt ggattttgat ttcaagccct tgaaaagttc aagcttttga gcagggagaa
    13921 gctctgcgtg acattcggaa agtccgagtt catttttaac attttcggca ggctgttgtc
    13981 tgtcgcctgt gagcattacc gtgttcttga caccgagcgc tttaagctgt gagataacct
    14041 cttttgcctc aggtcttacc gtatcgctga cattgagcga accgataagc tgaccgtcat
    14101 aaattacgaa aacagaatcg tctttatttg caatcttctt ctgttcgttc gaaagaatct
    14161 ttgaaccgcc gcactgaata gttttgccgt tataaactgc gcttgttccg tgaccggcac
    14221 tttcgctgta gtcggaaagc tcgggaagtt caagaccgtt tgccctttct ctgattgcgg
    14281 aggcaatcgg atgagcggaa tatttttcgc ttgcagcggc aagagcaaga acttcgtcag
    14341 cactgtatga accgaccgta ttaaccttgt ttacgctgag cttgccgctt gtgagcgtgc
    14401 ctgttttatc gaatacgaat gtgtctgctt ttgcaagagc ctcaatatat tttccgccct
    14461 tgatgagtac accgacttcg gatgccgcac cgatacccga atagtaggag agaggtacgg
    14521 aaataacaat agcacacgga catgacgcta caagacaaac aagtgcacgg tatagccatt
    14581 cgctgaatgc tccgagtccg caaagcggag ggattactgc gattgcaact gcaatgagta
    14641 caacaaccgg tgtgtaaacg gaggcaaatc ttgaaataag cttttcgctg ttgccctttt
    14701 gagcggcggc atcttcaaca agctgaagaa ttcttgttgc ggtactgtcg ccgaaatgct
    14761 ttgtggtttt gacggtaata aggttgctgc cgttgattgc gccgctgagt acctcactgc
    14821 cctcgcctgc atcaacagga aggctttcgc ctgtgagagc cgatgtgtcg agagtcgttt
    14881 tacctttgat aataatgccg tcaagcggaa ctctttcgta tggcttgact tcaatgatac
    14941 ttccgatttc aacgctttcg gcaggaacaa tctggtccgc accgtcaaca ataattgttg
    15001 ctgtatcggg acgaatgttt gcaagctttt caatgtcacg gcgggatgcg tcaactgctc
    15061 gatcctcaaa aatttcaccg atagaaaaga ggattgttac cattgccgcc tcaacaaaat
    15121 ctccaagaca gaatgccgca attaccgcaa cagccataag cgttgtttcg tcaattttca
    15181 gctttagaat gttttttgca cccttgataa ataccttgta acccgaaaga agtgttgcaa
    15241 caaaacacgc tgcgagtaca acataatgaa cagccgtaac accgtcaagt gtaaggtgga
    15301 gaatttcgga cactacagca agtacaattg aaattgcaag gaagattgtg tcatgattga
    15361 ttttcttttt cgtgatttcg ggttctgcct ttgttgtgac atcatttttc ggagttttgt
    15421 caacaacggt tacaccgtcc tcaatgctgt cgcagattgc ctgaatttcg gaaacaggat
    15481 tttgcttttc gcttttgaag ttgagaagtt ttgtcgcaaa attaaagctt acatcctcaa
    15541 agccgtctgt ttctgcaatt ttagcctcaa ttttgcccgc acaatgagca cagttgagat
    15601 tgtcaagctg atatttgtac ctcatatgtt tcccccttat tcaagaacat ggtcaagtcc
    15661 catttcgatg attcgtttca catggtcatc gtcaaggctg taatagatct gttttccttc
    15721 acggcgaacc cgcaccagct tgttctgcct taacacacgc agttggtggg aaattgtgct
    15781 ttgctccatg ttgagagctt cagcaatgtt gagcaccgac atttcatttt ccgaaatggt
    15841 gtacataatg cgaagtcggg ttgaatcacc gaaaacctta aaaaggtctg caagctcaaa
    15901 cagcacatca atgtcgggca tttcgggagt ggttgttttt tctttgtttt ccataggcgt
    15961 caccttttat tttctgtcag attaaaagtt atacttgaac atatgaagat atgctcatat
    16021 gttaattata atatagcatt ccctttttaa aaagtcaata gacacacacg aaaaagtgta
    16081 atatttttca agattttttg ccttaatatt tcgcttgttt attgcattcg tttggagagt
    16141 atatataata tagtataggg agaggatttt aaaatactca aaagcttggc aatgacatat
    16201 aaataacact tatttcaatt tgtaataatt ctacaaaaaa atctcttgaa ttattacctc
    16261 tttttaagaa aaatcaattc aaaaaatgat gcttggttat aataaaaaca aaaacagcaa
    16321 gaaatcaaca aattgagtac aacttgccca aaaatagatt acagttttat tattccgttg
    16381 actttactac aattttgtag tatcattttc tgtaggagaa ttgtatagtt acatctgcgt
    16441 aaccgagtag gtcccttttt aataaaatgt aacaaattag ttctcattcc gaattttaga
    16501 ttcgtgttat ttttgatttt tacttattta gatatatatt tcagatattt tttaaatatc
    16561 ttctacacat aattggggtg taacaattgg agaagttcgt agttaccggc ggaaagccat
    16621 tatcaggtga agtgacaatc agcggtgcga aaaatgcagc cgttgcaatt attccggcag
    16681 ttattctttg tgatgaaccc tgccaaatag aaaatattcc taacatcagc gatgtatcgc
    16741 tcatcagcag aattcttcag cagatgggtg ctaatgtaag acgaatcaac cgttcatctt
    16801 tgtatattga ccctacaaaa atccgcactt gcaatgcggt tacagacctt gtaagaggta
    16861 tgagagcatc atattatctt ctcggcgcac ttttgggcaa atacggcaag gcaaaggttg
    16921 ctcttccggg cggctgtaac tttggtgtgc gtccaatcga ccagcatctc aagggctttg
    16981 aggctctcgg agcaacaact cagcttgttg acggtgcaat tattgaggca gaatgcgaca
    17041 atcttgtggg tacacatgtg taccttgatg ttgtatcagt tggtgcaaca atgaacatta
    17101 tgcttgccgc ttcaaaagcc aagggtcaga ctattatcga aaatgccgca agagagccgc
    17161 atattgttga ccttgcaaac ttcctcaact caatgggtgc ggatgtcaga ggcgcaggta
    17221 cggatgttat caaaatccgt ggcgttgagt atcttcacgg cattacttat tcgattattc
    17281 ccgaccagat tgaggcagga acatatatgt gtgccgctgc cgcaacaaga ggttgtatca
    17341 cagtaaagaa tattacacca aagcatcttg aatcaatcag tgcaaagttg cgtgaaatgg
    17401 gtgttaagat tacagagtat gacgaggctc tcaaggttga tgcttcatct gctccgctca
    17461 agcgttgcaa tatcaagaca atgcctcatc cgggtttccc gactgactgt cagccacagt
    17521 ttgccgcatt gctcatgagc gttcccggca caagcattat taacgaaaat gtttgggata
    17581 accgctatca gtatgtcagc gaactcgtga gaatgggtgc acagatttct gttgaaggca
    17641 gacttgcaat cattgagggc ggtactccgc ttacagcagc tcccgttaag gcaacagacc
    17701 ttcgtgcagg tgcggctatg attattgccg ctcttgaaat caacggtaca accgagattt
    17761 caaacattca gttcattgag cgtggatatg aagatgttgt tgaaaagttc agagcgcttg
    17821 gtgcagacat caaaaaggtg tatttcacag gtgacaacga gcaggagctc ggtgcctgat
    17881 ttaaaactta attaaaaagc aaagccgttt tctttgtgag aacggctttt tatgtgcaat
    17941 gaaatttaca aattttaaaa tttgtgttat catatttggc agactataga taaggattga
    18001 ttgttttggc aagagcagtg ccgctgttca gcggaagtaa gggtaacagt tactacatag
    18061 gttcggcaac cgagggtgtt ttgattgacg caggtcgttc gtgcaagcag attgaaaatg
    18121 caatgcttgc aaacggaatt gatatgagca gtatcggggc ggtttttata actcacgaac
    18181 acacagacca ttgcagtgcg ttgcgtgtgc ttgcaaagcg ttacggcttt aaagtgtatt
    18241 caagtcttgg tacgctcaat gctttgaggg caggtaataa gcttgatcca aacacagatg
    18301 cagatgttat aacagacgag gttgtaatcg gcaatatgcg tgttcagcga tttgacacac
    18361 cgcatgatac ggctgaaagc tgttgctacc gagttaccgc tcctgacgga aaatccgcac
    18421 ttatagcaac cgatatgggt gttatgctgt ctgatgtcag aactgccgca gagcagagtg
    18481 actttgttgt gcttgaatca aatcacgata tcaatatgct caaaaacgga ttttatcctt
    18541 atccacttaa gcaaagaatc ctttcaaaca gaggacacct ttcaaatgaa gcgtgtgcaa
    18601 aggaacttgt caaccttgtt gaaaagggaa ctttaaggct tatgctcgga cacttgagtg
    18661 aagaaaataa taccgttccg cttgcaatgt caacatccgt tgacctgctc acatcaaacg
    18721 gaatgaagta caaaagtgac tattcgcttg atgttgcacc gagtatcagc acaaccaaaa
    18781 ctatcatctt ttaactataa ataagcgaga aaaatatgat taagattaac ataatttgca
    18841 ttggaaaaat caaggaaaag tattttaccg acgcaattgc agagtatgca aaacgcttga
    18901 ccgctttttg taaatttaat attgttgaac tttcggaaga acgcataaag agcaacactc
    18961 cgaatcagtc gcagattgac gaggttattt cttccgaggg aaaacgaatt atgcagaaaa
    19021 tttcaccctc cgactatgtt gtcgcaatgt gcattgaggg caagttgatg tcaagcgaag
    19081 agctttcaaa gctgattgac aacgcttccg ttagcggaaa aagtaccgtt gattttatta
    19141 tcggcggaag ttacggactt gacgaatcgg ttaagaaaag gtcggatgtt cgcctttcga
    19201 tgagcaaaat gacctttccg catcagatgg caagaatgat tttaagcgaa caaatttacc
    19261 gtgcatttga gatttcatca aatggtaaat atcacaaata atttacggag ttactatggc
    19321 acttgacgga atttttttaa gacatattaa aaatgaaata gaaaaagagg ctctcggtgc
    19381 aagagtgtcg cagatttatc agccaaacag ggaagaactc gtgttcggtc tgcgaacatt
    19441 ttcgggcaac aaaaagctgt tgctttctgc aagggcaaat tcaccgaggg tgaacttttg
    19501 ctcttcaaca cctgaaaatc ctgcacaacc gccaatgttc tgtatgcttt tgagaaaaag
    19561 aatcggcggc ggaaaattgg tgggacttcg ccagaacggt tgcgaccgtg ttcttatgct
    19621 cgactttgag tgcgtgaatg aactcggcga tacggtgatg ataaccgttg tctgcgaaat
    19681 tatgggcatg tacagcaaca taattattgt tgattcaaac ggtgttatca tcgactcgct
    19741 caagcgtgta gatcttacaa tgagcagtaa aagacttgta ctgccaaata taaaatacga
    19801 acttcccgaa tcgcagaaca agctgaatct ccttgaatgt actgcacttg atgtgtgtac
    19861 ggcggtaaaa aatcttgacg cggaaatgcc gcttaacagg gctcttttga gaacgattga
    19921 gggtgtttct ccgattgtct gccgtgagat tgaatataag gttatggagg gcgcaaccaa
    19981 cagaattgag ggtgtgcttt ttgaccgact cgcagttgaa atcgaaaagc tgaaatgcgt
    20041 ttgttccgac tgttcgggaa agcctgttgt ggtttaccgt gaggacggca agcctatgga
    20101 cttctgcttt atgaatgttg agcagtacgg cgattttgca aaggttgaga gtaaggaaag
    20161 cttctccgat ttgcttgacg gattctatga ggctcgtgac agtcgtgaca gaatgagggt
    20221 gaaatcacaa agtcttacaa agcttttgaa caataccctt gaaaggcttg cacgcaagat
    20281 tgcaaaacag cagagcgagc ttgaacgctg tgcagaccgt gagcatcttc gcatatgcgg
    20341 tgaccttttg caggcaaata tctatcgcat tgagcgtggc gcggagtatg ttgatgttga
    20401 aaacttttac gatgagaaca acgcaatttt acgcataaag cttaatccgg caatctcacc
    20461 ttcggcaaat gctcagaagt attacaagga ttaccgcaag gctaaaaatg ccgaaattat
    20521 gctcaaagaa cagcttgaaa agggcagaga agagcttgat tatatagact ccgttcttga
    20581 tacggttgac cgtgcagaga atgaaaaaga cctttcgcaa attcgtgaag agcttaccga
    20641 acaaggctat ctcaaaattc aaaagggcaa aaaggctcgt cagacaactc tgccgccgct
    20701 tgaatttgaa tcaagtgacg ggtttaaaat tcttgtcgga agaaataacc gtcagaatga
    20761 taagctgact ttgaaaacag cgtcaaagaa cgatatgtgg cttcatacaa aggacattca
    20821 cggttcgcat gtaattgttg tttcggacgg caaagagatt tccgacacgg caatctgtga
    20881 ggcggcacag attgcggcat atcacagcaa ggcgagaaac agcagtcagg ttcccgttga
    20941 ctacacactc gttcgctatg tgtcaaagcc aaacggctca aaacctggta tggtgattta
    21001 tgtcaataac aagacgctgt atgttaagcc gtcacagaca attgaaaagc agaaaattca
    21061 ataaaagaat taaacggaga gcgttttgcc ctccgttttt tgtatcaaaa ataaaaaatc
    21121 ggtttaaatt gaataatata ttccaaaagc gacagtgatt aacctcccgc ttgtttttat
    21181 taaacgcaaa tttgcactca cgcctaaaat cttttattag ttccataaaa gaataaataa
    21241 ttgtaattta tttaaaattg taaaaaatac atactaatag tattaactaa atcaagaaaa
    21301 tactattgat aataactaaa tgtgtgatat aataagcacg gaaggtatag cagcaatcta
    21361 aagtatttat gagcgcttat tatatgaatt tatgttccct taaaatcttg ccttgcaaaa
    21421 ttctcgatgg atgattatga tataaatttc tttggagatg attatatgga ttatattgct
    21481 catgctacgc cggataatag gacgcagaca gtgatcaaac atagcgtagg tgtgtttaat
    21541 aaaggcaaat cggatgcgga attgatatct gctttgaatt tatataaatt gtgcagttgc
    21601 ttgcacgata tgggtaaaaa cacattaaaa agcagcgagt atcaaaaaac tgtcggtttg
    21661 ggtaataagt ggagcggtgg aaaggttgtt cattcaaact gtggtggaag atttatctat
    21721 gaaacattta ttgaaaacaa tgataatctt gatgaatttg acgccttaac cgctgaattt
    21781 attgcaacgg taattatgtc gcatcacgga ctttttgaca ttttgaaacc tgacgatgat
    21841 aaaggtctta attatttcat cgaaaaaata cataatgaca gttatgatta tgcggagtgt
    21901 aagaaaaaaa cacttactga atttttagac ttggatacaa tcaagcagat tttttcaatg
    21961 gcaaaagatg aaataaaagc ctttgaatcc gaaaacgaat atcaagacag caggatgaat
    22021 aagtttagcc gttcaatgtt tgtccgtatg gtgctttcaa ttctgattaa cagcgatcat
    22081 gctgatgctg cagattttgc ttataaaacc gacactcatg atgagtatgt agacagtgaa
    22141 ttttggaaaa agtgttctga ctatcttgaa gaaaaaataa cgcattttaa aaatgatact
    22201 ttactcaata aaataaggtc agaaatttca aacaaagcct acgaattttc atctcaaccc
    22261 gccggaatag tgagaatgac agtccctacg ggaggaggaa aaacaatttc ttctttaaga
    22321 tatgccgttc atcatgcgga aaagtttaat aaacgaagaa ttatatatgt tgcacctttt
    22381 aattctatat tagaacaaaa ttatcttagc attaaagatt atttgcccga agatgttact
    22441 attttaccgc actttggcga ttggattgac aaaaaagact cggaatccga aagttcagaa
    22501 aacactctga aatatatttc agaatactgg ggtgcgccga taatagccac ctcaatggtg
    22561 cagtttttaa attctctttt tgacggcaaa attacttctc taagaagaat gagaggtctt
    22621 attgattctg tcataataat tgacgaggtg cagtcaattc ctattgattg ccttgttatg
    22681 tttaatcgtg ctgttgattt ccttgcaaag cattgcaaat gtacagtcgt actttgtaca
    22741 gcaactcaac cgccttttga aaaacttaaa gagggttttg ttttacccga aaattgcgag
    22801 atgattgacg aatttgccca ttactctcag cttatgaaaa ggactcaaat aattgataaa
    22861 attaaacctc gtggttacga ttctgaaaaa gcggcagatt ttataactga tttgcttgaa
    22921 aataatgaca gcattttgtg tgtagtgaat actaaaaatg ccgcaaggtc tatatacaaa
    22981 gaggttgatt taaaaatcaa atcatttgac ggcggcagta agataaaact tttctatctt
    23041 tcaactgcaa aatgtcctgc tcacagagaa aacgagattg atgaattgaa atcctgcctt
    23101 gagagaataa gaaacgcaaa tatagataat gagaagataa tttgcataag tacgcaattg
    23161 atagaagcag gtgtagatat atcgttcgat acggttgtaa ggtcactttc gggattaggc
    23221 aatattgt
//
