LOCUS       gnlProkkaGJHOPOAK_19   13812 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GJHOPOAK_19.
ACCESSION   gnlProkkaGJHOPOAK_19
VERSION     gnlProkkaGJHOPOAK_19
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 22:16:17
            Original ID  :: gnl|Prokka|GJHOPOAK_19
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13812
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13812
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[3461:3812]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3462..3812
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..13812
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13812
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             470..1981
                     /locus_tag="ctg19_1"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIENEPIASIDLMERAATVLTKAITDRWNT
                     ETPVTIFAGPGNNGGDALAVARMMAEKGYKIEVFLFNTKGELSPDCQTNKELVEMMEEV
                     KFHEISTQFVPPVLTPDHLVIDGLFGSGLNKPLSGGFAAVVKYINSSPAMVVAIDIPSG
                     LMGEENTFNVKANIIRADVTFSLQLPKLAFLFAENTEFVGEWEVLDIQLSEDGIEEMET
                     NYEMLEIEQIRSLIKPRKQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPMCNNDILQTSIPEAIVETDINETCFAVPTDTDDYQAVGIGPGLGRNEETEAALLEQ
                     LEHCHTPVVVDADALNILANHRHALTHLPKGSILTPHPKELERLTGKCQDSYERLMKAC
                     ELARAAHVHIILKGAYSAIITPEGKCFFNPTGNPGMATGGSGDVLTGVILALLAQGYST
                     EEAAKIGTYIHGLAGDVAQKKQGMIGMIASDIITCLPTAWQLVSE"
     CDS             2055..3122
                     /locus_tag="ctg19_2"
                     /transl_table=11
                     /translation="MKKLIIAAGLLMTTSAYAQTEVLTGVTRGKDYGVVYSLPKTQIEL
                     EIKANKVNYTPGEFSKYADRYLRLTNVSADPEEYWELASVKVKSVGVPNSETTYFVKLK
                     DKTVAPLMELTEDGIVKTINVPYSNSSVGKKAAPAPAVLQKKANPREFLTEEILMASST
                     AKMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNAQEEAMTQMFSGTCN
                     KEERTFTVRLTPDKEFNNEVAFRFSKKLGVVANNDLAGTPFYISLKDLKSVKMPQEDGK
                     KKKDLDGIAYNVPGQAMVTLTDGKKKLYEGELPITQFGVIEYLAPVLFNKNSTIKVYFD
                     PNTGGLLKVDREEGK"
     CDS             3159..3443
                     /locus_tag="ctg19_3"
                     /transl_table=11
                     /translation="MVGEGHAFDMIRRIKEGREASRLRRERANDKLKHLNRANEPYPLP
                     NTTPEEMERIIHDSEKKKEKDSNYFVWGTLIIMGVLIAIAVILWAVFIK"
     CDS             complement(3462..3812)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg19_4"
                     /sec_met_domain="PqqD_RRE (E-value: 2.2e-10, bitscore:
                     32.8, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 7.7e-17, bitscore: 54.0,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAKEKINLLEVIPCRSEHITAEREGETIVLSFPRFKYPWMQRFL
                     VPKGMSKELHVKLEEHGTAVWELIDGKRNVREIIEKLADHFQYEEGYESRVSAYLSQMQ
                     KDGFIKLVIPVV"
     CDS             complement(3910..5298)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 92.3; E-value: 4e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg19_5"
                     /transl_table=11
                     /translation="MTEHLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AISTTFPEGAMLFGFKTQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGTFHTNIPAPILFCLIMLCVGTIAFFLYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMIIGSVMLIFVHTMFAL
                     PILNIWWFATIIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNTYCKGPVVDGAQTYDYTLPMAIFALFGVLALIVALMLKAENKKKGYGLEEA
                     NIQK"
     CDS             complement(5547..5942)
                     /locus_tag="ctg19_6"
                     /transl_table=11
                     /translation="MYLLFVILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSIATAYVVPRSAVAKDAVLEQAQKEQQTNPYNLPAGTAAP
                     QTEAPATNAPATETPAPATETPAPAAE"
     CDS             complement(5949..6722)
                     /locus_tag="ctg19_7"
                     /transl_table=11
                     /translation="MTSVNFQQWIQHPETLNRDTLYELRNLLARYPYFQSLRLLYLKNL
                     YILHDISFGGELRKAVLYIADRRQLFRLIEGDRYDVQARKKGVPLTEVLKDEPSVDRTL
                     ALIDAFLSTVPEEVTARTSFDYSMDYTSYLLEETPATEQSAEETPKLKGYELIDDFIEK
                     SESDSPLCKKPLREEMPSSPTSSDELTEEETMKEEEEDDSCFTETLAKIYVKQQRYSKA
                     LEIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
     CDS             complement(6728..7255)
                     /locus_tag="ctg19_8"
                     /transl_table=11
                     /translation="MNWIKKIIRPLLLFGLPLVVIACTVSYKFNGSSINYDKVKTISIA
                     DFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPNQNADLQIDGEITGYNQYNQAVS
                     ADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTYDSSQLLTAVQDGLIAEMSKEI
                     TDQIFNATVANW"
     CDS             complement(7242..8483)
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 390.2; E-value:
                     2.3e-118)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg19_9"
                     /transl_table=11
                     /translation="MTKAEIQQVKQRFGIIGNTEALSRAIDVAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EADGGTIFLDEVGELPMSTQARLLRVLESGEFMKVGSSKVQKTDVRVVAATNVNLTQAI
                     AEGRFREDLYYRLNTVPIQIPPLRERGDDVLLLFRKFSADFAEKYRMPAIQLTEDAKKE
                     LLAYPWPGNVRQLKNITEQISIIETNREISAAILQNYLPAQNTQRLPALMGTRESKGFE
                     SEREILYSVLFDMRQEVAELKKMVHNLMAERAGQVGQVGQMGTVVTTPVVTAHQPSVPA
                     IIHTMQPTVCKDDDDIQDTEEYVEESPLSLDEVEKEMIRKALERHHGKRKSAAKDLNIS
                     ERTLYRKIKEYELD"
     CDS             complement(8493..9587)
                     /locus_tag="ctg19_10"
                     /transl_table=11
                     /translation="MEDNKIRIGITQGDINGVGYEVILKTFSDPTMLELCTPIIYGSPK
                     VAAYHRKALDIQANFSIVNSATEAGYNRLSVVNCTDDEVKVEFSKPDPEAGKAALGALE
                     RAIEEYREGLIDVIVTAPINKHTIQSEEFSFPGHTEYIEERLGNGDKSLMILMKNDFRV
                     ALVTTHIPVREIATTITKELIQEKLMIFHRCLKQDFGIGAPRIAVLSLNPHAGDGGLLG
                     MEEQEVIIPAMKEMEEKGILCYGPYAADGFMGSGNYTHFDGILAMYHDQGLAPFKALAM
                     EDGVNYTAGLPIVRTSPAHGTAYDIAGKGVACEDSFRQAIYVAIDVFRNRQREKVARAN
                     PLRKQYYEKRDDSDKLKLDTVDED"
     CDS             complement(9592..10632)
                     /locus_tag="ctg19_11"
                     /transl_table=11
                     /translation="MKKYSFILCIALVAFVVASCGLKGNHTSSGRAYELLVVVDHGVWD
                     RAAGRALHDALDADMPGLPQSEPSFRIMYTSPKDYDSTLKLIRNIIIVDIQDIYTKASF
                     KYAKDVYANPQMILTIQAPNEEEFEKFVEENKKTIVDFFTRAEMNRQITFLEGKHSNFI
                     SQKVDSLFGCDIWVDAELANSKTGDDFFWASTNTGTADRNFVMYSYPYTDKDTFTKEYF
                     VHKRDSVMKANIPGFKEGVYMSTDSLLTDVRPINVQNSYTMEARGLWRMKGDFMGGPYV
                     SHTRLDEKNQRIITAEIFVYSPDKMKRNLVRQMEASLYTLKLPNEVQQKQIPLGEASKE
                     AEQTNK"
     CDS             complement(10651..11685)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg19_12"
                     /sec_met_domain="PF04055 (E-value: 1.3e-17, bitscore: 57.2,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKYPLLGMTLVELQSLTKRLGMPGFAAKQIASWLYEKKVASIDD
                     MTNLSLKHRELLKQNYEVGAEAPVDEMRSVDGTVKYLYKVGENHFVESVYIPDDDRATL
                     CVSSQVGCKMNCKFCMTGKQGYTANLTASQIINQIHSLPERDKLTNVVMMGMGEPLDNL
                     DEVLKALELLTATYGYAWSPKRITLSTVGLRKGLQRFIEENDCHLAISLHSPLTVQRAE
                     LMPAEKAFSITEMVELLKNYDFSKQRRLSFEYIVFKGLNDSQVYAKELLKLLRGLDCRV
                     NLIRFHAIPGVDLEGADMDTMTRFRDYLTSHGLFTTIRSSRGEDIFAACGMLSTAKQEK
                     NNES"
ORIGIN
        1 gaagaagaca gttgaaataa aaaagagatt accaccaaat ttgacgaaga accgaaatct
       61 ttggttcttc gtcaaattcc gtgctactta tttatgttca attaccttat tcatggctat
      121 tccggagtac tttaagatgc atatagtttg gataatttat ttgctatttc taatatgccg
      181 atatcccttt atccatcggc ctttcaatga gctttactag cacggaattt gattaagaac
      241 caaatctttt tcaggagaaa taaaagtaag ttcataatgg tgctgcattg aattattttt
      301 tggcggagtt attctaacac ttaatagttc aaaagcagat atttctctga cccaaagata
      361 gaactaatga tgaattaaaa gttgcaatta tggttttctt cccacaacaa acgggaaaag
      421 tcagaagaat catgtacatt tgtaatccga aaactaaaag aacatcgcaa tgaaaatatt
      481 tccaagcagc agtatcaaga aattggacgc ttataccatt gagaacgaac ctattgcatc
      541 aatcgatctg atggaacgtg cagcaaccgt attaacaaaa gccatcacag acagatggaa
      601 tacggaaacg ccggtcacta tctttgccgg accggggaat aatggcggag acgctctcgc
      661 cgtagcccgc atgatggctg aaaaaggata taaaatcgag gtatttctct tcaacacgaa
      721 aggagaactt tcacccgact gccaaaccaa taaagaactg gtagaaatga tggaagaagt
      781 aaaattccac gaaatcagta cccaattcgt acctcccgtc ctgacgcccg accatctggt
      841 aatcgacgga ttattcggtt caggcctgaa caaaccgtta agcggcggat tcgctgccgt
      901 agtgaaatac atcaattcct cccctgctat ggtagtagcc atcgacattc cttccggact
      961 gatgggagaa gaaaacacat tcaacgtaaa agctaatatt atccgtgccg acgtaacttt
     1021 cagtctgcaa ctgccgaagc tcgcctttct tttcgcagag aacacggaat ttgtcggaga
     1081 atgggaagtg ctggacatcc aattaagcga agacggtatt gaagagatgg aaacgaacta
     1141 cgaaatgttg gaaatagagc aaatccgttc actcatcaag ccacgcaaac agtttgccca
     1201 caaggggaac ttcggccatg cactattgat tgccggttca aaaggaatgg caggagcctc
     1261 tgttctcgct gcccgcgcct gcctccgttc gggagtaggg ttgctgactg tccatgcgcc
     1321 aatgtgcaac aacgacatct tgcagacctc catacccgaa gcaatcgtag aaaccgacat
     1381 caacgaaacc tgttttgccg tacctaccga cacggacgac tatcaagcag tcggcatcgg
     1441 cccagggctg ggacgaaacg aggaaacgga agctgcttta ttggagcaac tggaacattg
     1501 ccatactcct gttgtggtgg atgccgacgc acttaatatc ctcgccaacc accgtcatgc
     1561 acttacccac ctgccgaagg gttccatcct caccccgcat ccgaaagaac tggaacgtct
     1621 gaccggcaaa tgccaggact cttacgaacg tctgatgaag gcttgcgaat tggctcgtgc
     1681 cgcccatgtt cacattattt taaaaggagc ctactccgcc attatcaccc cagaaggtaa
     1741 atgtttcttc aacccaaccg gaaatccggg aatggcaacc ggaggtagcg gtgacgtact
     1801 gaccggagta atcctggcac tgcttgccca aggttactca accgaagaag ccgctaaaat
     1861 cggcacttac attcacggat tggcgggcga tgtcgctcaa aagaagcaag gaatgatcgg
     1921 aatgatcgca agcgatatta tcacctgtct gccgacagca tggcaacttg taagcgaata
     1981 aaagttaaga acttaccctt ttttcaataa cttcattaac tttgttttca aaaccagtta
     2041 aaaaagaacc gaatatgaaa aagttgatta tagcagcagg actactaatg acaacgtccg
     2101 cctatgcaca aaccgaagta ctgacagggg ttacccgagg aaaagactat ggagtggttt
     2161 acagtcttcc caaaacccaa atagaacttg aaataaaagc caacaaagtc aactatactc
     2221 cgggagaatt cagcaaatat gctgatcgtt acctgcgact gaccaacgtc tccgccgacc
     2281 ctgaagagta ctgggaactg gctagcgtaa aagtgaaatc cgtaggtgtg cccaacagcg
     2341 aaactacgta tttcgtaaaa ttgaaggata agacagtagc accgctcatg gaactgacag
     2401 aggatggcat tgtgaaaacg atcaatgttc cttacagcaa tagcagtgta ggcaaaaaag
     2461 ctgctcccgc ccccgcagtc ctccaaaaga aagcgaatcc tcgtgaattc ctgaccgagg
     2521 agattctgat ggccagctct accgccaaga tggccgagct ggtggctaaa gagatctata
     2581 acatccgcga aagcaaaaat gccttattgc gcggacaggc tgacaatatg ccttcagacg
     2641 gagcacagct taaaattatg ctcgacaatc tgaatgcaca ggaagaagcc atgacgcaaa
     2701 tgttctccgg cacctgcaac aaagaagaga gaacattcac tgtccgcctt acccctgaca
     2761 aggaattcaa caatgaagtt gctttccgct tctcgaagaa gttaggtgta gttgccaaca
     2821 atgatttggc aggaactccg ttttatatca gtctgaaaga cctgaaatcg gtcaagatgc
     2881 cacaggaaga tggtaagaag aagaaagatt tggatggaat cgcctacaac gtccccggac
     2941 aagctatggt tacactgacc gacggtaaaa agaaacttta cgaaggtgag cttcctatta
     3001 ctcaatttgg tgtgatagaa tatctggctc cggttttgtt caacaagaat tctaccatca
     3061 aagtttattt tgatccgaat acgggaggat tgctcaaagt ggacagagaa gaagggaaat
     3121 agaaaaacga ggaagtaaac ttctaaaaaa caaagaatat ggttggtgaa ggacatgcat
     3181 tcgacatgat acgccgaata aaagagggac gggaagcttc ccgcctacgt cgtgaacgtg
     3241 ctaacgataa gttgaagcat ctaaaccgtg caaacgaacc ttatccacta cccaacacca
     3301 cccccgaaga aatggaacgt atcatccacg actcggagaa aaagaaagag aaagacagca
     3361 attattttgt ttggggaacg cttattatca tgggggtcct gatagcaatt gccgtcatac
     3421 tttgggctgt atttatcaaa taaataataa taagttccta tttatacgac tggtatcacc
     3481 agttttataa atccatcttt ctgcatttga gaaagataag ccgatacacg cgactcgtag
     3541 ccctcttcat attgaaagtg gtctgcgagt ttttctataa tctcacgaac attgcgtttt
     3601 ccatctatca gttcccatac agccgtaccg tgttcttcca atttcacatg aagttctttc
     3661 gacattcctt tcggcacaag gaagcgttgc atccacggat atttaaaacg gggaaaggag
     3721 agcacaattg tctccccttc cctttctgct gtaatatgtt cactgcgaca gggaatgacc
     3781 tctaacaggt tgattttctc tttggcagcc atacttctta ttttttattt cagagtattc
     3841 atactgatac tcttctgttt acaccttgat acaaaattcc tttgtcactt taggtattga
     3901 atttcccagt tacttttgga tattcgcctc ttccagaccg tatcccttct tcttgttctc
     3961 tgcctttaac atcaaagcca caatcagagc aagcacacca aagagagcaa aaatagccat
     4021 cggcaacgtg tagtcataag tctgtgcacc gtctactacc ggacctttgc aataagtatt
     4081 caacacccat ccgatcaaca aaggaacacc catcaatccc cagttctgta cccagaaaat
     4141 caatgcgtat gcggtaccca actgtttttc cggaataatc ttcggaacag acggccacat
     4201 agctgaaggc accaacgaga aggcaaatcc caatataatc atgatgatag tagcaaacca
     4261 ccatatattc agtataggca gagcgaacat cgtatgcaca aaaataagca tcactgatcc
     4321 gattatcatc aacgtagctc ccttaccgat acggtcataa agcgagccga acaacggagt
     4381 caggataatc gcaccaatcg gcaacaatcc gggaatcgtt cccgccaact tcggatctac
     4441 attatacttc tgcaccatca agtcggcagc atacttgata aaggggaata cagccgagta
     4501 gaacaataca catagtaatg caatcaacca gaatccctta ttcgtaatga tatacacaat
     4561 atctttcata cggaacggtt cttccggttc caatccctct gcatccaaag aagcatccaa
     4621 cttcttatca tagaaagtat aaaggaagaa agcaatcgta cccacgcaca acataatcag
     4681 acaaaacaaa atcggagcag gaatattggt atggaatgtg ccactctcat ccgtagatcc
     4741 gaagaagtcg gccaaaggaa ccgtgagcac cattgccaga gttgttccga tacgtgccgt
     4801 agccatttca agtcccatag ccaatgccat ttccttaccc ttgaaccatt ttacgataat
     4861 tttggaaact gtgataccgg caatttccac acctacaccg aagatagcat accccaatgc
     4921 ggccagggtt acctgtgttt tgaatccaaa gagcatggca ccttccggaa aagtagtaga
     4981 aatcgcatag tatttcaatc cacaaccaaa caccatcaat aagcaagccc ccattccggt
     5041 gaaacgaact cccatcttat ccaaaatgat accaccgaaa atcagcatca acaggaatac
     5101 attaaaccac ccgtaagcgc ttgtgaagaa accataatca agactgtccc atagtagttc
     5161 tttctcaagc atgggtttta gaggagacat tacgtcggtg aggaaatagc cgcatagcat
     5221 agtaaatgcg accaatgcta gaacactcca tcggagtacg gcggagtcat tcaatttctg
     5281 tttcaaatgt tctgtcattg ttatatttaa aaaagtagtt aataatcttc atacgaccaa
     5341 caaaggtagt taaatctcgt ttgtttctat caaaaagaga ttgtttttac aagaaaaagt
     5401 taagtgcgga ttacactgac cacgcggaag attgaaaatc cgtgtaatct gcgtaatccg
     5461 cacttaaata tcaaagaaat gcagcatccg tctgcacctt cccattaatg gttttacccc
     5521 aaagtcttac ctgacaacgg agtgaattac tctgctgcag gagcaggagt ttcagtagcc
     5581 ggtgccggag tttctgtagc aggtgcattg gtagcaggag cttcagtttg cggcgcagcc
     5641 gtacctgcgg gtaagttata cgggttagtc tgttgttctt tctgtgcctg ttccaacact
     5701 gcgtctttag caacagcaga gcgaggaact acataagcag tagcaatgct cattaccacc
     5761 atgaagatag ctaagcccca tgttgctttt tccagaaaat ctgtagtctt gcgcacgccc
     5821 atgatggcgt tagatgaaga gaaaccagaa gcaagtccgc ctccttttga gttctgaatc
     5881 agcacgatga aacacatcaa caaggctgca ataaccatta agataacgaa taataagtac
     5941 atttttagtt attttgaatt agcgttaata atcaatttct ccaaaaatct gatttggtct
     6001 gcaaagtaag catttttttt tggatatttc aagcttaatt ttttaattat ttcaagagct
     6061 tttgaatatc gttgctgttt aacatagatt tttgccaaag tttccgtaaa acagctgtca
     6121 tcttcctctt cttccttcat tgtttcttct tcggtaagtt cgtccgaaga ggttggcgaa
     6181 gatggcattt cttctcttaa aggtttcttg cagaggggag agtcgctctc gctcttttct
     6241 ataaagtcgt caatcagttc gtagcctttg agtttgggcg tttcttcggc cgactgttcc
     6301 gtggccggag tctcctccaa aagataagag gtgtaatcca tcgaatagtc gaagctggtg
     6361 cgggcagtca cctcttcggg tactgtagac aagaaagcgt cgatcaatgc taatgtgcgg
     6421 tctacggacg gttcgtcttt cagcacctcc gtgagaggta ctcccttttt ccgtgcctgc
     6481 acatcatagc ggtcaccttc aatcaaccgg aacaactgcc gtctgtctgc aatgtaaaga
     6541 actgctttcc gcagttctcc accgaaacta atatcatgga gaatatacag attcttcaga
     6601 tacagcagac gaagtgactg aaaatacgga tacctcgcaa gaagattgcg cagttcgtac
     6661 aaagtatccc tattcagcgt ctcgggatgc tgaatccatt gttgaaagtt aacagaagtc
     6721 atttatatta ccagtttgct acagttgcat taaaaatttg gtcggtgatc tctttagaca
     6781 tttcagcaat caatccgtcc tgtacggcag tcagcaactg gctagagtcg taggtacgga
     6841 acgcagaaaa ctgttgttca aagtcttcgg catgattggt gttgttgaca aaacgtacat
     6901 tgacggtaat agtcaacttc gtctccgaag agtaaccgtc ggcagatact gcctggttgt
     6961 actgattgta tcctgtgatt tctccgtcaa tctgcaagtc cgcattctga ttcggcttga
     7021 gcagttgcag acgggtctgc cggatgaaga tatctttcag gtcctcattg aatttggttg
     7081 ctaacggagc atatacatac tccgacttga tcgggaagtc ggctatcgaa atggtcttta
     7141 ccttatcata attgatagac gatccgttaa acttatagga aacagtgcac gcaatgacta
     7201 ccaacggcaa gccgaacagt aacaaagggc gtattatttt cttaatccaa ttcatattct
     7261 tttatttttc tataaagtgt acgctcggaa atattcaagt ccttggccgc actcttccgc
     7321 tttccatgat gcctctcaag tgccttgcgt atcatttctt tctccacttc gtccagtgac
     7381 aaaggggatt cttctacata ttcttccgtg tcttgtatgt catcatcatc cttgcaaacc
     7441 gtaggctgca tggtgtgaat gatagcaggt accgaaggtt gatgcgccgt cactaccgga
     7501 gtagtaacca ccgttcccat ttgtcctacc tgccccacct gtccggcacg ttccgccatc
     7561 aggttgtgca ccatcttctt cagctccgcc acttcctggc gcatatcgaa cagaacagaa
     7621 taaagaatct cccgttcgct ctcaaagcct ttactctcac gcgttcccat caacgcggga
     7681 agacgttgcg tattttgtgc aggaagataa ttctgcaaga tagcagcaga gatctcccta
     7741 ttggtttcaa tgatagatat ttgctcggtg atgttcttca actgacgcac gtttccgggc
     7801 cacgggtaag ccaacaactc tttcttcgca tcctccgtca actgaatagc gggcatccgg
     7861 tatttctctg caaagtctgc ggaaaactta cgaaacaaca aaagtacatc gtcaccacgt
     7921 tcacgcaaag gcggtatctg gataggcacc gtattcaacc ggtaatataa atcttcacgg
     7981 aaacgtcctt ctgcaatcgc ttgtgtaaga ttgacgttgg tagccgccac cacacgcaca
     8041 tccgtttttt gtactttgga cgaacctact ttcataaact cgccactctc cagtacacgg
     8101 agcaaacgtg cctgggtaga catcggcaac tcccctactt catcaagaaa aatagtacca
     8161 ccgtcagctt cgccaaagta ccctttccgt tcgccaatcg caccggtaaa cgcacctttc
     8221 tcatgtccga acagttcgga atcaatcgta ccttccggaa tagcgccaca gttgacagca
     8281 atatactgtc cgtgcttcct ccggctatat tgatgaataa tctgcggaaa actttctttt
     8341 ccgactccac tttctccggt aatcagcaca gacaaatcgg taggagctac ctgaatggca
     8401 acatctatgg cgcgcgacaa tgcttcagta tttccaataa taccgaaacg ctgtttcact
     8461 tgttgtatct ctgctttcgt catcactcgt ttttaatctt cgtctactgt atccagcttc
     8521 agtttatcac tatcgtcacg tttctcgtaa tactgtttac gcaacggatt ggcacgagcc
     8581 actttttccc gctgacgatt acggaacacg tcgatggcaa catagattgc ctgacggaaa
     8641 gaatcttcac aagccactcc cttgcctgca atatcgtatg ccgttccatg agccggagaa
     8701 gtacgtacta tcggcaggcc tgccgtatag ttcaccccgt cttccatagc caaggcctta
     8761 aacggagcca gcccttgatc gtgatacatc gccagaatac cgtcaaaatg agtataattg
     8821 cccgaaccca taaagccgtc ggccgcataa ggaccgtagc aaaggattcc tttctcttcc
     8881 atttctttca tggcagggat aatcacttcc tgctcttcca ttcccaacaa accaccgtct
     8941 ccggcatgag gattgagaga gagcaccgca atacgcggag cgccgatacc gaaatcctgt
     9001 ttcagacaac gatggaatat catcagtttc tcctgaatca gttctttggt aatcgtagtc
     9061 gcgatctctc tgacagggat atgtgtcgtc accaaagcca cccggaagtc attcttcatc
     9121 aaaatcatca atgacttatc accattaccc agacgttctt cgatatattc cgtatgtccg
     9181 gggaaggaga actcttccga ctgaatcgta tgtttgttga tcggagctgt tacgataacg
     9241 tctatcaacc cttcgcgata ttcttcgatg gcacgttcca aagcccccag cgcagcttta
     9301 ccggcttcgg ggtcgggttt ggaaaattcc actttcacct catcatccgt acagttcacc
     9361 acgctcaaac ggttgtaccc cgcttcggta gcagagttga caatgctgaa attggcctgt
     9421 atatccagcg ctttgcgatg ataagccgct actttcggtg agccataaat gatcggagta
     9481 catagttcca acatcgtagg gtcggaaaat gtcttaagaa tcacctcata gcccaccccg
     9541 ttaatatctc cttgggtgat acctatcctt atcttgttat cttccatgtt tttatttatt
     9601 agtttgttcc gcttccttag atgcttctcc caatggaatc tgcttctgct gaacttcatt
     9661 cggaagtttc agtgtataca gagatgcttc catctggcgt accaggttgc gtttcatttt
     9721 atcaggtgaa taaacaaata tttctgctgt aataattcgt tggtttttct cgtccagacg
     9781 agtatgagat acatacggac cacccataaa gtcgcccttc atacgccaca ggccacgtgc
     9841 ttccattgtg tagctgttct gtacattgat cggacggaca tcggtcagca aactatcggt
     9901 cgacatataa acgccctcct tgaatccggg gatattggct ttcatcacgg agtcacgttt
     9961 gtgcacaaaa tattctttgg taaacgtatc cttgtcagtg tacggataag agtacatcac
    10021 aaagttacgg tcggcagtac ctgtgttggt agaagcccag aagaaatcat ccccggtctt
    10081 tgaattagcc agttcggcat ccacccagat gtcgcatccg aacaaactgt ccactttctg
    10141 cgaaatgaaa ttactgtgtt tcccttccag gaacgtaatc tgacggttca tctccgcacg
    10201 ggtaaagaag tcgacaatcg tctttttgtt ctcttccaca aacttctcga actcttcttc
    10261 gttcggagcc tggatagtca atatcatctg cggattggca tacacgtcct tcgcatattt
    10321 gaacgaggct ttcgtatata tatcctgtat atctacaata ataatgttac gtatcaactt
    10381 cagcgtagaa tcataatctt tcggcgaagt atacataatc cggaaagaag gttccgactg
    10441 cggcaaaccg ggcatatcag catcgagcgc atcatgtaaa gcccttccgg cagcacgatc
    10501 ccaaacaccg tgatctacta caaccaaaag ctcgtaagca cgaccactag aggtgtgatt
    10561 tcctttcaga ccacaagatg caacgacaaa ggctaccaaa gcgatgcata aaataaaaga
    10621 gtactttttc atgatgttcg gttttatata ttaactttca ttatttttct cctgtttcgc
    10681 tgtcgacagc ataccgcaag cggcaaaaat atcttcgccc ctggatgaac ggatagtggt
    10741 gaaaagtccg tgtgacgtca gataatcacg aaaacgggtc atcgtatcca tgtccgctcc
    10801 ctcgaggtct acccccggta tggcatgaaa acgaatcaga ttcaccctgc aatccagccc
    10861 gcgaagaagt ttcagcaact ctttggcata gacctgcgaa tcattgagcc ctttaaaaac
    10921 aatatattca aacgaaagtc gacgttgttt actaaaatca tagtttttta acagttccac
    10981 catttcggtg attgaaaacg ccttttccgc cggcattaat tcagcacgct gaacggtcag
    11041 cggagagtga aggctgatgg caaggtggca gtcattttct tcgataaaac gctgcaatcc
    11101 tttccgtagc ccgacagtag aaagcgtgat acgcttcgga ctccatgcgt aaccgtaggt
    11161 agcggtcagt agttccaatg ccttcaatac ctcatccagg ttatcgagcg gctcgcccat
    11221 tcccatcatt acgacattag tcagtttgtc ccgttccggc agcgaatgaa tctggtttat
    11281 gatctggctg gcggtcaggt tagctgtata cccctgtttg ccggtcatac agaacttaca
    11341 gttcattttg cagcccactt gtgacgacac gcacaacgtt gcccggtcat catccggtat
    11401 ataaaccgac tctacaaaat ggttctcacc cactttataa agatacttca ccgtaccatc
    11461 tacagagcgc atttcatcta ccggagcttc cgctcccacc tcatagttct gcttgagcaa
    11521 ctcccggtgt ttcaatgaca aattagtcat atcatcaatc gaggctacct tcttttcgta
    11581 aagccaggat gcaatctgct tggcagcaaa gccgggcata cccagtcttt ttgtcaatga
    11641 ttgaagctct acaagagtca ttcctaaaag gggatattta gacattcttc tttctgttga
    11701 tagtttatat ctgcaaatgt aaggaaataa agtcgatttc cgtatagcag gaatgtaaaa
    11761 gttaacaaaa aagggaagta tgcctccgtt atgattcaac cacgctgata tattgaagta
    11821 gcttttgcgc catttcagaa tcctcgccat tctttttcac ttcataaccg tacgcctcac
    11881 ggaaacaagc cagcgcctct tcccgttcat tacaaaagct gtgcaaaacc cctaagttct
    11941 gacaagccag aatcgtatct tcttcctccc atcccagata tttctttcgc agttcaagct
    12001 ctctgaagaa agcctctttc gccattggat aattctccaa cttcacataa gcctgtgctt
    12061 tgtaataata taccagacag gaagcattag ggtcagcatc atcgtgaaaa tccaaagacg
    12121 ttgcaatacg aatcacgtta tcatagtctt tattcatgta atactgctgc ataatatcac
    12181 atctcaatgc ctcgtagcgg acagtcagtt ccgccagacg cggtttttcg ctgaaataca
    12241 tttcatgcag aagagactca cggaagaata aagtagacgc ctgctcatcg ccacgttcat
    12301 tcatcatccg tttgaattcc ctgcatagat aatacaactg tttatgacaa gcgacgatct
    12361 gtcttttgct gtctatctgt atagcaatgt ccaacgcctg attcatcagc atccatgctt
    12421 catcgtatcg tttgatataa taaagacatt taccctgcat acgcaaacat ttagccactc
    12481 caccagacag tctgccattc aacgactcgt gcatttcagc tactttccgg aatttctcgg
    12541 cagccctctc ttcctcatcc ttatagtaat cacaataagc cagatattcg gaaagttcaa
    12601 tgacttctgc ctgactcttc tcatcagcag aagccgcatg ataatcaagc gccctattca
    12661 aataggtcac tgcttcattg tattgctcat tgtagtaata tgccagagct agatttcggc
    12721 aggtgttggc aatctccagt tccggagtcg gtactatgtt ttcctgcatc accaatgctt
    12781 tcaggaaaca gtcgcatgcc gtttcgtact cttcattacg ggcataccgg catccctcat
    12841 tcatcttcaa taccgacttg gcaatgagtg gcatggcagc accttccata ctcttctcac
    12901 tcacagcagc tgccgccttc gtcagatgga aagaactgct caagaaagta gccatatcat
    12961 tagcaatgac aggaattaaa aaagaatcga tctcatcaaa gtccaattca gcatagactt
    13021 caggcgtaac ttcaggattg tcgttcatga tcgccttcca gctatcttcc aacagagaac
    13081 gattcgtgcg atacagaatc tcgaaaatct ccacatcaca aatccaatcc ttcaatatat
    13141 cccattcttg catcttatag cattgatagg taatctccac tttatagcga tacgaatcat
    13201 ggtagcagaa ctgtttcatg cgatagttat aatcggcaaa agtcaacgga tgggaaagga
    13261 tctcttcctc atccagcaga gcggaaataa tttcatggcg actatcatct atacattcgt
    13321 catcttgagc gaaatagcgt tcgatcgcct ctaccatttg tgtatcacca atgcaatatc
    13381 gtcctccttt gttggtgagc cagctgctca tttccactct caactgcgac caaagtatct
    13441 gattaatgtc tgccatgctc ttcacttcat cttcggtaaa tccttctaaa gtaagtgaaa
    13501 gcatcagaag cgttcttcca atctcttcgg aaccataatc agccgacaaa cgccgtagca
    13561 cactgtcata gaattgccca acctcattga gccggcaata tccacgcata tattcattga
    13621 gagcatcgta ctgaccgaac gaaaccagct cgttgagcaa tacacttaaa cagcgcggtt
    13681 gttcagccag cacccacgaa gcaagaatat cttcctgctg tgcagacaaa gccttggagt
    13741 aagtagacaa atattgcttt gagaacgact tggcatccgc ctgtgaaaag ccattcaact
    13801 ggaaatgagc gt
//
