Select genomic region:
Overview
1.1
1.2
8.1
10.1
17.1
26.1
40.1

### Identified primary metabolite regions

c00001_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_1)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 1.1 | Pyruvate2acetate-formate | SCFA | 1 | 14,393 | Pyruvate to acetate-formate E. coli | PFL_acetate | 100%
Region 1.2 | pdu | SCFA-other | 58,238 | 100,034 | Propanediol degradation S. enterica | PDU | 54%

c00008_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_8)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 8.1 | Others_HGD_unassigned | Putative | 34,522 | 58,760 |

c00010_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_10)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 10.1 | succinate2propionate | SCFA | 28,012 | 52,984 | Succinate to propionate B. theta | PRO | 25%

c00017_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_17)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 17.1 | OD_AA_metabolism | Putative | 28,834 | 56,848 | PFOR II pathway B. thetaiotaomicron | PFORII | 100%

c00026_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_26)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 26.1 | Rnf_complex | E-MGC | 1 | 17,342 | Rnf complex C. sporogenes | RNF | 100%

c00040_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_40)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 40.1 | acetate2butyrate | SCFA | 1 | 17,451 | Acetate to butyrate C. sporogenes | BUT | 100%

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 1.1 | Pyruvate2acetate-formate | SCFA | 1 | 14,393 | Pyruvate to acetate-formate E. coli | PFL_acetate | 100%
Region 1.2 | pdu | SCFA-other | 58,238 | 100,034 | Propanediol degradation S. enterica | PDU | 54%
Region 8.1 | Others_HGD_unassigned | Putative | 34,522 | 58,760 |
Region 10.1 | succinate2propionate | SCFA | 28,012 | 52,984 | Succinate to propionate B. theta | PRO | 25%
Region 17.1 | OD_AA_metabolism | Putative | 28,834 | 56,848 | PFOR II pathway B. thetaiotaomicron | PFORII | 100%
Region 26.1 | Rnf_complex | E-MGC | 1 | 17,342 | Rnf complex C. sporogenes | RNF | 100%
Region 40.1 | acetate2butyrate | SCFA | 1 | 17,451 | Acetate to butyrate C. sporogenes | BUT | 100%

No primary metabolite regions were found in these records:
  c00002_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_2)
  c00003_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_3)
  c00004_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_4)
  c00005_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_5)
  c00006_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_6)
  c00007_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_7)
  c00009_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_9)
  c00011_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_11)
  c00012_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_12)
  c00013_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_13)
  c00014_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_14)
  c00015_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_15)
  c00016_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_16)
  c00018_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_18)
  c00019_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_19)
  c00020_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_20)
  c00021_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_21)
  c00022_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_22)
  c00023_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_23)
  c00024_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_24)
  c00025_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_25)
  c00027_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_27)
  c00028_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_28)
  c00029_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_29)
  c00030_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_30)
  c00031_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_31)
  c00032_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_32)
  c00033_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_33)
  c00034_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_34)
  c00035_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_35)
  c00036_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_36)
  c00037_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_37)
  c00038_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_38)
  c00039_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_39)
  c00041_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_41)
  c00042_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_42)
  c00043_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_43)
  c00044_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_44)
  c00045_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_45)
  c00046_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_46)
  c00047_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_47)
  c00048_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_48)
  c00049_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_49)
  c00050_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_50)
  c00051_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_51)
  c00052_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_52)
  c00053_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_53)
  c00054_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_54)
  c00055_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_55)
  c00056_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_56)
  c00057_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_57)
  c00058_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_58)
  c00059_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_59)
  c00060_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_60)
  c00061_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_61)
  c00062_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_62)
  c00063_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_63)
  c00064_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_64)
  c00065_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_65)
  c00066_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_66)
  c00067_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_67)
  c00068_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_68)
  c00069_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_69)
  c00070_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_70)
  c00071_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_71)
  c00072_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_72)
  c00073_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_73)
  c00074_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_74)
  c00075_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_75)
  c00076_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_76)
  c00077_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_77)
  c00078_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_78)
  c00079_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_79)
  c00080_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_80)
  c00081_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_81)
  c00082_gnlPro.. (original name was: gnl|Prokka|NGHLIMDL_82)

Compact view
c00001_gnlPro.. - Region 1 - Pyruvate2acetate-formate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 1 - 14,393 nt. (total: 14,393 nt) Show pHMM detection rules used
Region on contig edge.
Pyruvate2acetate-formate: ((PFL_acetate1 or PFL_acetate2) and Radical_SAM)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00001_gnlPro.. - Region 2 - pdu
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 58,238 - 100,034 nt. (total: 41,797 nt) Show pHMM detection rules used
pdu: (minimum(2, [Aldedh, BMC, Cob_adeno_trans, EutN_CcmL, Fe-ADH, Fe-ADH_2, PDU_like, PTAC, PduV-EutP]) and Dehydratase_MU and Dehydratase_SU and Dehydratase_LU)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00008_gnlPro.. - Region 1 - Others_HGD_unassigned
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 34,522 - 58,760 nt. (total: 24,239 nt) Show pHMM detection rules used
Others_HGD_unassigned: (minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl, Carboxyl_trans, CoA_trans, CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans, CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III, ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C, BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C, Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

c00010_gnlPro.. - Region 1 - succinate2propionate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 28,012 - 52,984 nt. (total: 24,973 nt) Show pHMM detection rules used
succinate2propionate: (minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not Cytidylate_kin)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00017_gnlPro.. - Region 1 - OD_AA_metabolism
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 28,834 - 56,848 nt. (total: 28,015 nt) Show pHMM detection rules used
Region on contig edge.
OD_AA_metabolism: (minimum(1, [PFOR_II, POR, POR_N]) and minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA, Urocanase]) and not (Gly_radical_scatole or Gly_radical or Gly_430_pcre or Gly_8-9_TMA))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00026_gnlPro.. - Region 1 - Rnf_complex
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 1 - 17,342 nt. (total: 17,342 nt) Show pHMM detection rules used
Region on contig edge.
Rnf_complex: (Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00040_gnlPro.. - Region 1 - acetate2butyrate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 1 - 17,451 nt. (total: 17,451 nt) Show pHMM detection rules used
Region on contig edge.
acetate2butyrate: (not (POR or POR_N or PFOR_II) and minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF, ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1, ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4, Thiolase_C]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.