LOCUS       gnlProkkaNMMECHGA_1    22954 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NMMECHGA_1.
ACCESSION   gnlProkkaNMMECHGA_1
VERSION     gnlProkkaNMMECHGA_1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 23:53:57
            Original ID  :: gnl|Prokka|NMMECHGA_1
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 256881
            Orig. end    :: 279835
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22954
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12954]"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12954
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     cand_cluster    1..22954
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="interleaved"
                     /product="sactipeptide"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     region          1..22954
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="sactipeptide"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     protocluster    235..21467
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10234:11467]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      10235..11467
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="2"
     CDS             411..950
                     /locus_tag="ctg1_268"
                     /transl_table=11
                     /translation="METNKPTLYWSLLMFKNWNFYIASTLKGLVFVGSQNKPIEELFEW
                     ARKRFPGSLLVEDDDKLEPYAVEITQYLEGKRKNFTVPVEYAGTQFQLAVWNALCEIPY
                     GQTKSYSDIANEINKPAAVRAVGAAIGANPVLITVPCHRVIGKNGSLTGYRGGFEMKTL
                     LLDLEKRASSEMDVPH"
     CDS             1469..2986
                     /locus_tag="ctg1_269"
                     /transl_table=11
                     /translation="MLVSLSLSSLLTLFFIMLMASGISGLLFLHPRVPLSFVRIHIGIL
                     ALPLLVSLLILANSGVSGNVGPWHLDSLACLMTFFVLAIGFIIQRFSVRYLMGDRSYRK
                     YFALFTFTTGSASMTWLSGDLRLMVLFWGATLVGLTLLIRLNSAWQVASEAAKISGRLF
                     LLSWFSLFFAMMWLFHATGQWQLSLVVTNESLAGLGEWERTGIQLLIVLAVIIPAAQWP
                     FQRWLVESIVAPTPVSAIMHAGLVNAGGIILTRFSPLFHGGIASIILLLLAGISVLIGT
                     GISLVQVDYKRQLVGSTIGQMGFMLIQCALGAYIAAIIHLILHGLFKATLFLQAGSAVG
                     RHEVSARTNERTSYLWAMAGRILSLVIGVAFWLTAPGDGYHLISALILGWSLSVSWTQL
                     VAFGEGRIGRIAGLTVLGGAALVYFIIHNLFYKWLHTTIFQSVQPPMSAVMIVVCLLLF
                     GSALGTWVARHRSSVFFAVLYLWLVRLGEAKPKSVESHPDYLKQYIS"
     CDS             3001..5616
                     /locus_tag="ctg1_270"
                     /transl_table=11
                     /translation="MGITSVLTKDNVKKIDTDIDVQEGDLNVFITSASRVIAPLWPIST
                     FAARNPWMGLENQPFDQVASWLKNTRDVDIYPSASMIRSAKNKGEIDEDFVEMGLQRWL
                     DSHSYHIPRDVAERFCHAALKLDPLPSDLLSSHELEKLVGECSGLDHIENVFMQPLSSY
                     IENQDGERLVNILDHHVIKWSKLYLDDSQAGWTMPNREEGFYRAWQHLIQYDPALSKKQ
                     RERVKDWPKEAHLALQEALFALEIPESEIQTYLEGHLLSLPGWAGMMLWRSQQSSHEHA
                     LLTEYLAVRISMEWALIKPYLPLTNERSKKTISIAPLIAAWIHWGGLTLEEWSQMTAIE
                     QNEYLSFAYSFDEKLRKKLWLEAWEQTYTDRLSQKIISKQRETGGEKSALAQLAFCIDV
                     RSEPFRRQLEKEGPFETIGIAGFFGVPIATCELGSKHSHASLPIIQKPQNKIKEFADED
                     VFKKYNQRKQAIHSLSHTFKTMKQNALSSLLLPELSGPWLTLQMAARSFVPRKAGRFIR
                     NLREAWLRKPDTKLSLHHDATEAEIPVGFTDEEKVNYARQALKMMGLTENIAPLVVICG
                     HGSQSTNNPYSAALDCGACGGAAGGFNARVLAALCNLSEVREALLAEGIKIPEDTVFAA
                     AEHNTTVDELHWLYVPELSEAAQEAFEQIEAVMPKVRHHVNAERLAQLPNFQSKLKNPK
                     AEADRFAEDWSEIRPEWGLARNAAFIIGKRELTQDCDLEGRAFLHNYDWKQDESGELLA
                     NIIAGPGTVAQWINLQYYASTVAPHYYGSGNKATQTVTAGLGVMQGNASDLLAGLPWQS
                     VMESDHEAYHSPLRLLILIQAPREYVERLLNNDSAFLQKVQNGWVRLASLDPEGCWESW
                     "
     CDS             5693..6220
                     /locus_tag="ctg1_271"
                     /transl_table=11
                     /translation="MNVNQNKKVLFLTDIENGLEPILQEATNTSAENMLTIQSYGASIS
                     HPYGEIMRSVIFAIYQEDVEEIFVVGTKDKKTSAGNGLTQLETMKDKIQTLDYLFQNCK
                     PEFFGGTVDEWLNENSSDTIEKSVDMIRHHPLVPSYVKVRGLFVNHNDGKPSIVEVPDA
                     KTGQAIPDHCLS"
     CDS             6177..6284
                     /locus_tag="ctg1_272"
                     /transl_table=11
                     /translation="MLKQVKPYLIIACHDEMQVQLLNTIYGESSSKEIV"
     CDS             6281..6571
                     /locus_tag="ctg1_273"
                     /transl_table=11
                     /translation="MSANLTDFVTKTIEDMNSFDRENMECMKKLIRKAIDFYHLKSYEE
                     VEETHSGNVRFLHVHSMMEENMLSKMIVVTRNGKTDLDIEGVYEGYVVREY"
     CDS             6629..7003
                     /locus_tag="ctg1_274"
                     /transl_table=11
                     /translation="MKKSKGSIESEISKSITQWEKDYLGRGSVSVKTDILRDMIIVNLK
                     GILTPAEYVVCGSKEGMLSIKQTRSELVESGIEGLKDIILKITGEKVKSFHTDLSSRTG
                     ERVMVFKLCNDLEKNLEKIL"
     CDS             7487..7789
                     /gene_functions="regulatory (smcogs) SMCOG1058:ArsR family
                     transcriptional regulator (Score: 67.7; E-value: 1.1e-20)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_275"
                     /transl_table=11
                     /translation="MEPIEVFKALSNESRLQILQWLKEPDRHFAPHEGIDMNTIGVCVS
                     QITDKLKMTQSTASQYLTILLRAGLIKAERIGKYTYYKRDEEAIGKLADFLKTEI"
     CDS             7916..9088
                     /gene_functions="transport (smcogs) SMCOG1184:major
                     facilitator transporter (Score: 336.3; E-value: 3e-102)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_276"
                     /transl_table=11
                     /translation="MSNTWKIYILAIVSFLVGTSEYIISGILDQIAHTLGITLAAAGQL
                     ITIFSLVYALSTPVLMALTASMDRRKLMMYALGLFVFGNVLAFVLPGYGWFIAARIIMA
                     MGAGVVVVTALTIAAKIASEGKQGSAIATVVMGFTASLIIGVPLGRMIAVALGWKSVFG
                     AIALLGLIAMVVIFFTLPHTEGDKPVPLLQQLALFKKRKVAMGLSITFFWLGGYSVAYT
                     YLSPYLLNISGINGKLLSGVLLIFGIASLVGSKFGGYSTDKWGVPFTLVGGMTLHIVTL
                     ILLSLVTHSYIGVLVILILWSFAAWSTGPTQQFHLATIEPEMSGVLLSMNQSMMQFAMA
                     VGAGIGGVFVENVSLASITWVGALGVMIAIIASLLIFNSQPKQALKDINQ"
     CDS             10001..10168
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: TIGR04404"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_277"
                     /sec_met_domain="TIGR04404 (E-value: 4.7e-37, bitscore:
                     123.7, seeds: 3, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRNQKEWESVSKKGLMKPGGTSIVKAAGCMGCWASKSIAMTRVC
                     ALPHPAMRAI"
     CDS             10235..11467
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Other_Sactipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SPASM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_278"
                     /sec_met_domain="Other_Sactipeptide_rSAM_RRE (E-value:
                     2.7e-14, bitscore: 51.4, seeds: 13, tool:
                     rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 2.8e-21, bitscore: 74.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 5.1e-06, bitscore: 24.8,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 5.2e-05, bitscore: 21.7,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYDRVKDFDLPELAVHLQPHGAVMIDRKSMFYFRLSGRGAQLAF
                     LLSKNKNLHKTARIWEIMKKEEMSADQLKEELSAHPFTEAWTEGLLDQPLHVSGSLDSY
                     LPISCTLQLTNACNLSCSFCYASSGKPYPEELSSEQWILVMQKLAAHGVADITLTGGEA
                     KLIKGFKELVVVASSLFTNVNVFSNGLNWRDEEVELLSHLGNVSVQISIDGMDNTHDQL
                     RGRKGGFKESMNTIKKLSEANIPVIVAMTINESNADEVSDVVEQCANAGAFIFRAGKTL
                     SVGRATEGFKALDIDFEEMVQIQLREARHKWGDRLNIIDWEHEESSFTTDFCTPGYLAW
                     YIRADGYVTPCQLEDLPLGHILEDSMADIGSPARLLQLKCEAKNCKCIGKIELSEPDLP
                     FQKEVKAGIQE"
     CDS             11464..12954
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: skfc"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_279"
                     /sec_met_domain="skfc (E-value: 1.2e-287, bitscore: 952.7,
                     seeds: 3, tool: rule-based-clusters)"
                     /sec_met_domain="Abi (E-value: 9.7e-13, bitscore: 46.4,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSLSLVFWSILAVVGLLLFIKFKPPTIASLLLSKDEAKEISIQF
                     IKEFVGIEVENWDFYSVYWYDHDTVNKLHHLGILKKNRKVLYDVGLVESWRVRFVHQNQ
                     SFVVGVNANREITFFYADVPKKTLSGKFEQVSPETLKQRLMASPDGLWSRANMTGTGKK
                     EEDFREVSTYWYIAEAGDIRLKVTVELQGGRISYIGTEQEILTDQMSKVIRDEQVESTF
                     GVSGMLGSALAMILAILILVFMDVQTSIIFSLVLGLLIIICQSLTLKEDIQLTIVNAYD
                     ARMSVKTVSLLGILSTLLTGLLTGFVVFICSLAGNALAGDFGWKTFEQPIVQIFYGIGA
                     GLISLGVTSLLFNLLEKKQYLRISPELSNRTVFLSGFTFRQGLNMSIQSSIGEEVIYRL
                     LMIPVIWWMSGNILISIIVSSFLWAVMHQVTGYDPRWIRWLHLFIFGCFLGVLFIKFGF
                     ICVLVAHFIHNLVLVCMPLWQFKLQKHMHHDQPKHTSL"
     CDS             12973..13695
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 178.6; E-value:
                     2.6e-54)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_280"
                     /transl_table=11
                     /translation="MQLMQVQNLSKCYRNGDGVEHLSFSIQRGEIVALLGPNGAGKTTT
                     IRCLTGLYKPDKGDILIEGSPPGDINVQKKVALIPDQPYLYPALTAAEHIQFRARGYHP
                     GKKDVKERVYHALKEVHLEEKANQLCGQLSRGQKQRVVLAGAIVQDALLYILDEPTVGL
                     DIPSKQWLSNWLKTKTDQGCSAFVSTHSLEFVIETADRVILIRDGKLMQDLYVPQFEEE
                     QAEWRKEVIRLLGEWSDE"
     CDS             13760..15103
                     /locus_tag="ctg1_281"
                     /transl_table=11
                     /translation="MPFLIMLLFVGAIGFQVSFVSRSTTWDMSIAGWVLTGVFILYTAF
                     GLFSNRLPSQMADIIWLYGTATSFSKVVYSVLFFSVTWKALLWIISAIFGDVLIVLLSG
                     DHINLLGRSIIFVGLFFIAEVWLMSVSCARTVKKMKRVYVLVFLLMLGIYSICLYHFFF
                     LQHSSGIWESIARFISGVGLVFDTLSPLYVVVFIGIITVSFMTIAFTSSQVEMKESLVK
                     EAEFWEEFQERQFGSGQIIQKPKTTWWGLQGLNGIWSFLWLELLLFKKYLFFHSIHTVM
                     LSGVFYVVIFMYPEWFYLLFFLIVSAVMLSSYYSGIVRHSQSGTLHLFPGALWKKIIIL
                     ELTNTVWLYILYCVSITFMAVGNLVYWYIYGLGIYIWFMTIRLFAFTHTNRNDPRLSLP
                     QYYKSFFMALGLSGICLYVIHLLTADWYTLVVVVCIGSLSWCLFYRFR"
     CDS             15150..15665
                     /locus_tag="ctg1_282"
                     /transl_table=11
                     /translation="MNSNGDKLSLSVQNLANTNEITIVQAIGELKKSGKDAIPVLVEAL
                     KEEGSLCNIAAAVLGEFGEDASEAAEELSCLLKSHAEDTRMAAAISLMRIGKPSLPFVI
                     KIAQESEGQSCFWASWCIAWIDPSCIEPKMYKCLKYEHEHPSGIVAPFAAEEALGKLIA
                     FQLKDKED"
     CDS             15670..16095
                     /locus_tag="ctg1_283"
                     /transl_table=11
                     /translation="MKDEQMLTEWPSHLPWLNQSQNDFTFPSDTYLLLYFWSMSCPHCH
                     QLTDKVLQDIKDMNVKVIGVHVPYIEEEKSMEVVLTYALDRGLAIPIVLDQNYEIVTTC
                     HVQGIPSFCLLSQYGQIITKTMGDVGWDKMLKKIAGL"
     CDS             16512..17327
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_284"
                     /sec_met_domain="PF00561 (E-value: 4.1e-07, bitscore: 27.9,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNVYLEGSGKDTFVFMSGSGIAAPAYEMKGLYSKFSKENKIAVVD
                     RAGYGYSEVSHDDRDIDTVLEQTRKALMKSGNKPPYILMPHSISGIEAMYWAQKYPKEI
                     KAIIAMDIGLPQQYVTYKLSGVDRLKVRGFHLLTSIGFHRFMPSAVYNPEVIRQSFLTD
                     EEKEIYKAINFKQFFNADMEHELLQSYQNGSKSVNLPAPKETPVLILDAVSDQNRHSKY
                     AIQTRKDYEAFAAQFNTADIKELRGTHSIYLYQPDQIYKLSMEFMRKVC"
     CDS             17329..18000
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 126.2; E-value: 2.3e-38)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_285"
                     /transl_table=11
                     /translation="MKGYHILIVEDDVMIGDLLQKILQREGYRVIWKTDGADVLSVIQK
                     VDLVIMDVMLPGEDGYQMSAKIKKLGLGIPVIFLSARNDMDSKLQGLQIGEDYMVKPFD
                     PRELLLRMRNMLEHHYGTFTQIKHLYIDAVTKKVFNESLYDEVLFTAIERKIFFYLYEN
                     RDSILTKEHFFEYLWQLEDRNPNIVNVHIKKIRAKINDQAGEMIENIYGEGYRLNTVVK
                     K"
     CDS             17997..18983
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 57.8; E-value: 1.8e-17)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_286"
                     /transl_table=11
                     /translation="MKLKTKYQLLLFTAVISVPMLLLAVSVLMSVIYDSMFKPMNHGMP
                     FHRSFAYPAMIVVFLISLLLLAFLFSKSIHSLLHKINLLNQTIRHLASDQRVPDKIEVK
                     RADEIGELIKSVNLLIERTTYRELELRQQEEIKKELLQKLRHDINTPLTALRLQLFYLE
                     DQCHGQAVFESLYQQIEYISELTNEFNLYSAETLESSYIVNEEVRLNELLETAVKKWDY
                     LYSMSGIELHYKAADQDVIWMSNALWMQRLFDNIFQNTLKHSKAEKMEVTIEHDNVFIR
                     DDGIGLDRNESSEGLGLKIIEDTCRLLAITYELHTNDSGTGFLFSKE"
     CDS             19042..19305
                     /locus_tag="ctg1_287"
                     /transl_table=11
                     /translation="MNIICLKKSSKRLSTSQAVLVTDIADTGITAAAGADIIAATAAAR
                     AKEDTTTVMAAVIVTNAGATAAVNPKKVLVPLLGQGFFYVID"
     CDS             complement(19290..20060)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1030:serine/threonine protein kinase (Score: 111.5;
                     E-value: 8.2e-34)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_288"
                     /sec_met_domain="Pkinase (E-value: 7.5e-32, bitscore:
                     108.7, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALKLLKKLLFDRPLKNGVILNHQYKIEECLGMGGYGLVYLCTDI
                     LTQTPYVLKQLRPTKAKKEKEKVRFQQEIKLLKSIHHPQIPGFIDEFIIDGQAYYVMQF
                     IEGENIEELLFFRKQPFTELMALQLISQLLEIIEYLHDRLIFHSDIRTPNIIINDGRLC
                     LLDFGLAKQLTLEEMEEIKVRKQDDFFDLGETLLFLLYSQYKGKKKKNGTWLEELTLTK
                     EVTLLLKRLLGIDKEYQHTASIREDLNRAIQSIT"
     CDS             complement(20146..21003)
                     /locus_tag="ctg1_289"
                     /transl_table=11
                     /translation="MVKKWLIPFAVMLSVLFTFTYSASAVGVTAITGNNSFDTAMPIGY
                     WKYKNIDTTILEAGQDEAYFTFTANKGEKVYVRSTYQSAYTGMKIEIYDKNRIPVSQGT
                     EVINPNTFSSFIYANADAQNTTDTFYVKVSRGTYTGNMYFTLSIEDRIKSGSGTFQFSG
                     VAENKGNTSLSPSGSDSSVIKVDLTNQSGIPRDAIVTRVQTTATQTPSQGNTRHLIMTN
                     ENNEWRRALVNSSTSGSYDISLSDQLSVAKVWSFKYNTLATARSTMSNVKAKIDYEYDV
                     TKQF"
     CDS             21135..22319
                     /locus_tag="ctg1_290"
                     /transl_table=11
                     /translation="MRLNRQFIRTQLMAQNILSKNAPAKRENATENPAAVLEKAYSRLK
                     SQSSTGGINQFNYSKTSVSGNSGAFSKVYQSANDRTVTDTGEETVIQSQNPYESESDIR
                     IKILDEKYSRMNAINKTKSDPLGYIKDKYQNSKSPYFRSDLSAAERQAAYDNETEWLFK
                     GKAQNYNLQDAAFRNVTFHGEVEAENEKVYQRGQVNQQLQVLLNRNHIHIPEGTELTFT
                     ITPIDYQVRVSGTDDQDLIKQIEQVLQSGDNSKELFLHIMKSQSSDSTQFSEEAYQKYQ
                     AAREMYEVTGYHLKDLEVIDGRYVTPDGRDLIDVYKEELEKDPVQKQTASYAISYYRSE
                     LSKIVEAGYNAIPDFILSIDYSNGSLRDVGQSKSYGTGDTGWLEALKRQTGVNY"
ORIGIN
        1 tccaaacgca gaacaagctc tccgcgcaaa ttttcgccct tgtaaacgtt gcaagcccac
       61 taatgaaaaa atgcctgata gcgagtgggt tgatttaatt actgaataca ttgataaaaa
      121 tttcacagaa aaattaacgc tagaatcgtt agcagatatt tgtcatggga gtccgtatca
      181 tatgcatcga acatttaaaa agattaaagg cattacgctg gttgagtata tacaacaagt
      241 tagagtacac gcggctaaaa agtatttgat tcagacaaat aaatcgattg gagatatcgc
      301 tatatgtgtg ggtatagcta acgcgcctta ttttattact ttatttaaaa agaaaactgg
      361 acagacacca gcacaatttc gtcaaatgag taaaatggag gaaacgtaca atggaaacaa
      421 ataaaccaac cctttattgg tctttactaa tgttcaagaa ttggaatttt tatattgctt
      481 caactttaaa ggggcttgtg tttgtaggtt cacagaacaa accaatcgag gaattgttcg
      541 aatgggctag gaaacgcttt ccgggaagtc ttcttgttga agatgatgat aagcttgaac
      601 cctatgccgt tgaaatcact caatatctag aaggaaagcg gaaaaacttt actgttccag
      661 ttgagtacgc cggtacgcaa tttcagctag cagtctggaa tgcactttgt gaaattcctt
      721 atggacagac gaaatcctat tccgacattg caaatgaaat aaataaacca gcagctgttc
      781 gtgctgtagg tgcggctatt ggggctaatc cggtattaat tactgtaccg tgccatcgtg
      841 taataggaaa gaatggctca ttaactggct atcggggcgg attcgaaatg aagacactgc
      901 tcctcgatct ggaaaagcga gcttcatctg aaatggatgt tcctcattga aagtgaatca
      961 tctataatag ggtggattct tttagaggaa agtaaagacc agtttactga taaacttgac
     1021 aacttttaaa atttagcata tcttatacgt aacttaataa tcgatgcaga tgtttatttt
     1081 tccttttaaa atatgtaggc ctttagcatt cttttcatat ttaattttaa atattgacag
     1141 gatgaaaaag tatcctaata aaaaaggaag agaacatgag tcgatttatt tgataatcag
     1201 gactatatta aaggaaatga aaacatagca taaagtaaag accaataata aggtagcact
     1261 tcaaaaaact tcgctgaagt tagttgaagt gaagccgaca attttcagga ttcaatgatc
     1321 taacataatc attgaaattt tgaagttgtc ggcttttttg ttggaaaaaa atagagataa
     1381 ataaaaattg aaataaataa tagacaaata tgatctgatt gaaaggtctt ttgaacaata
     1441 atgagtttta aaaaagggag aatttagaat gttagtttcg ctgagtttgt catcattatt
     1501 aacattattt tttattatgc ttatggcttc tgggataagt ggactattgt ttttacatcc
     1561 gcgagtaccc ttgagttttg ttcgcattca tattgggatc ttggctttac cacttttggt
     1621 ttccttactg attcttgcca atagtggtgt gagcggaaat gttggccctt ggcacttaga
     1681 ttccttagct tgtttaatga ctttctttgt tcttgcaatt ggattcatca ttcagcgttt
     1741 ttctgtacgt tacttaatgg gggatcgatc ttatcgaaaa tattttgcgc tttttacttt
     1801 cacaacagga tctgcttcaa tgacatggtt aagtggcgat ctccgcttga tggttctatt
     1861 ttggggagca actcttgttg gtttaacctt acttataagg ttaaacagtg cttggcaagt
     1921 ggctagtgaa gcagccaaaa tttctggccg gttatttttg ttaagttggt tttctctgtt
     1981 ttttgcaatg atgtggcttt ttcatgccac aggtcaatgg cagttatcat tggttgtaac
     2041 aaatgaaagt ttagctgggc tgggagaatg ggagagaaca gggattcagc tattgattgt
     2101 actggcggtg atcattcctg cagctcaatg gccattccaa agatggttgg ttgagtctat
     2161 tgttgctcca acccctgttt ctgcaattat gcatgcaggt ttagtaaatg ctggaggaat
     2221 aatactaact cgattttcac ctctatttca tggtggtatc gcttcgatta tcttacttct
     2281 gcttgctggc atttctgtat tgattggaac tggaattagt ttagtccagg ttgattataa
     2341 acgccagtta gtaggctcca cgattggaca aatggggttt atgctcattc agtgtgcatt
     2401 aggcgcctat atagcagcca ttattcatct tattttacat ggtttattca aagctacgtt
     2461 gtttctacaa gctggttcag cagtagggcg tcatgaagta tcggctcgca ctaatgaaag
     2521 aacatcctat ttatgggcca tggctggtcg gattttatcc ttagttatag gtgttgcttt
     2581 ttggctcact gctcctgggg acgggtatca cttaatcagt gcgctgatct tagggtggtc
     2641 attgtccgtt tcttggactc agcttgtcgc ttttggagag ggccgaattg gccgaattgc
     2701 tggcttaact gttttaggag gagcagccct cgtatatttt atcattcata accttttcta
     2761 taagtggctg catacaacca tttttcaaag tgttcaacct ccaatgtcag ctgtcatgat
     2821 tgtcgtatgt ctcttactct ttggcagtgc tttaggtacg tgggttgctc gtcatcgttc
     2881 ttccgttttt ttcgcggtac tctatctttg gttagtccga ttaggtgaag caaaaccaaa
     2941 gtcagtagag agtcacccag actaccttaa acaatatatt tcataaggag ctaatctgag
     3001 atgggcatta catccgtatt aacgaaagat aatgtaaaaa agatagatac agatattgat
     3061 gttcaagaag gggatcttaa cgttttcatt acatctgcca gccgagtgat tgcgccactt
     3121 tggcctattt ctacatttgc tgcacgtaat ccgtggatgg gacttgaaaa ccaacctttt
     3181 gatcaggttg caagttggtt gaaaaacact cgcgatgttg atatataccc tagtgcgtct
     3241 atgatccgtt cagcaaagaa taaaggtgag attgatgaag attttgtgga aatggggctg
     3301 cagcgttggc ttgattcaca ttcctatcac atcccacggg acgtagcaga gcgattttgt
     3361 catgctgcat taaagttaga tcccctgcct tccgaccttt tatcatcaca tgagctggag
     3421 aaattagtag gtgaatgtag tggattggat catatcgaga atgtgtttat gcagccacta
     3481 agttcgtata tagagaatca agatggtgaa aggctagtca atatactaga tcatcatgtc
     3541 attaagtgga gtaaattata tcttgatgac tctcaagcag gctggacaat gcctaatcgt
     3601 gaggaaggtt tctatcgtgc ttggcagcat ctcattcaat atgatccagc acttagcaaa
     3661 aagcagcgag aaagggtaaa ggattggccg aaagaggcac atttggcttt acaggaagcc
     3721 ttattcgcac tagaaatccc agagtcagaa atccagactt atcttgaagg tcatttactt
     3781 tcattacctg gatgggcagg gatgatgctt tggcgctccc agcaatcgag ccacgaacat
     3841 gcactcctaa cagaatattt agcggttcga atatccatgg agtgggctct tataaagcca
     3901 tacttacctt tgactaatga acgatctaag aaaacaattt caattgctcc ccttatagca
     3961 gcttggattc attggggtgg gcttacatta gaagaatggt cacagatgac ggccattgaa
     4021 caaaacgaat atttatcatt tgcctacagc tttgatgaga aacttcgcaa gaaactttgg
     4081 ttagaagctt gggaacaaac gtacactgat cgattaagcc agaagatcat ctcgaaacaa
     4141 cgtgaaaccg gcggtgaaaa atctgcatta gctcaattag cattctgcat cgatgtacgg
     4201 tcagaacctt ttcgtcgtca actagaaaaa gaaggcccgt ttgaaacgat tggtattgct
     4261 ggtttcttcg gggtgccgat tgcaacttgt gaacttggca gtaaacacag tcatgcttcg
     4321 ttaccgatca tacaaaaacc gcaaaataaa ataaaagagt tcgcagatga ggatgtattc
     4381 aaaaaataca atcaacggaa gcaagcaatt cattctttaa gccatacctt taaaacgatg
     4441 aagcagaatg cgctttcgag cttactactg cctgagctaa gcggaccttg gctaactctg
     4501 caaatggcag cccgtagctt tgtgccaaga aaggcaggtc gtttcattcg taatctccgt
     4561 gaggcttggt tgcgcaaacc tgatacaaaa ctctcgcttc atcatgatgc tacagaggca
     4621 gaaatacctg tgggttttac tgatgaagaa aaagtgaact atgctcgcca agcattaaaa
     4681 atgatggggt taacagagaa catcgcacca ttggtcgtaa tttgcgggca tggcagtcaa
     4741 agcactaata atccttattc tgcagccctt gattgtggtg cctgcggtgg agcggccggt
     4801 ggattcaatg caagagtttt agctgcttta tgtaatctat cagaggtacg agaagctctt
     4861 ttagctgaag gaattaaaat tcctgaggat acggtttttg cagcagctga acataataca
     4921 acagtagatg aattacattg gctttatgta ccagagcttt ccgaagctgc acaagaagca
     4981 tttgaacaaa ttgaagccgt tatgccgaaa gtgagacatc atgtaaacgc agaacgtcta
     5041 gcccaattac cgaatttcca atcgaagcta aaaaatccga aggctgaggc agaccgattt
     5101 gcggaagatt ggagtgagat acgtccggaa tggggactgg ctcgtaatgc cgcttttatt
     5161 atcggtaaac gtgaactaac tcaggattgt gatttggaag gcagagcctt tctccataat
     5221 tatgattgga agcaggatga aagcggtgaa ctcctagcaa atattattgc aggacctgga
     5281 actgtagccc aatggattaa tttacaatat tacgcatcaa cggtagcacc tcattattat
     5341 ggcagcggaa ataaagcaac tcaaaccgtt actgcaggtc tcggcgttat gcaggggaat
     5401 gcaagcgatt tgttagccgg actgccttgg caatccgtca tggaatcaga tcacgaggcc
     5461 tatcattctc ctcttcgttt attgatactc atccaagcac ctagagaata tgtagaacgg
     5521 ttattaaata atgattcagc atttctgcaa aaagttcaaa atggatgggt ccgactggct
     5581 agtcttgatc cagaaggatg ttgggaaagc tggtaatgat gaatctaagc atttatcaaa
     5641 tggatttgtt attcaaaata aaaatgataa acataaggaa gaggtgtgct gtatgaatgt
     5701 aaaccaaaat aaaaaagtat tatttttgac ggatattgaa aacggtttgg agcctatttt
     5761 acaagaagcg actaacactt ctgcagagaa tatgttgact atacaaagct atggtgccag
     5821 tatttcacat ccttatggag aaatcatgag gtctgttatt tttgcgattt atcaggaaga
     5881 tgttgaggag atttttgtag taggaacaaa agataagaag acttccgcag gtaatggact
     5941 aactcaactt gaaacaatga aagataaaat acaaacattg gattatctct ttcaaaattg
     6001 caagcctgaa ttttttggtg gtacggtcga tgaatggcta aatgaaaata gcagtgacac
     6061 cattgaaaaa agtgttgata tgattcgaca tcatccacta gtgccgtcat atgttaaagt
     6121 tagaggttta ttcgttaatc ataatgatgg aaaaccctca atcgtggagg ttcctgatgc
     6181 taaaacaggt caagccatac ctgatcattg cttgtcatga tgaaatgcag gttcaacttc
     6241 taaacaccat atatggtgaa agcagttcta aggagattgt atgagcgcta atttaactga
     6301 ttttgtcacg aaaacaatag aggacatgaa ctcgtttgat cgtgaaaata tggaatgtat
     6361 gaaaaaacta attagaaaag caattgattt ttatcatcta aagtcttatg aagaagttga
     6421 ggaaacccat tcaggaaatg ttcgattttt gcatgtccac tctatgatgg aagaaaatat
     6481 gttatccaaa atgatagtgg tcacaagaaa cggtaaaact gatttggata ttgaaggtgt
     6541 atatgaagga tatgttgtaa gagaatatta atgagacgaa atcacaaata gaatatgcca
     6601 atttttttgc tcaggagatg tattagatat gaaaaagtcg aagggttcta ttgaatcaga
     6661 gatcagtaag tccattactc aatgggagaa ggattatctt ggacgggggt ctgtatctgt
     6721 taagactgat atactgcggg acatgatcat cgtcaattta aaagggattt taacaccagc
     6781 cgaatatgta gtttgtggat caaaagaggg tatgttatct atcaaacaaa ctcgttcgga
     6841 gttagttgaa tcaggtatag aaggccttaa ggatattatc ttaaaaataa ccggagaaaa
     6901 agtgaaaagt tttcatactg atttaagctc ccggacaggt gaacgagtga tggtatttaa
     6961 attatgtaat gatctagaga aaaatttgga aaagatctta taatctaaag aaaataaatg
     7021 ttaagacggt atggaatttg ttgtgaattg aacataaaga actgccgatt cttttgtttt
     7081 acaattatgg tatcattgat aacttttatt catatcctaa gcggacataa agagatgtca
     7141 attcatagta cactgttgtg ttattcctgt cgaaagatct aacatccgct gttgttatga
     7201 gcggatgttt tttacatcta aatttgctgc tggtgattag tcacttgaac aatattaaat
     7261 tcattttaat tgaaaacatc cttgtcacct gccgggttcc cccaagtgtt tagtgacatg
     7321 attatgagac caatttcgta aagcttgatg ataaatttaa gcggtgaaca aaattgatat
     7381 gctgtcttca gtttcatttc acggaattag tcagagataa acctttaatt aaaaatatcc
     7441 aaaaaaacgg attgacatat cggaatataa cgatataata atcgatatgg aaccaattga
     7501 agtattcaaa gccttatcaa atgaatcaag gctgcaaatt ttacaatggc tgaaggagcc
     7561 cgatcgtcat tttgcacccc atgaagggat tgatatgaac acaatcgggg tatgtgtcag
     7621 tcaaataaca gacaaattga aaatgacgca atcgacagct tctcaatatc ttaccatcct
     7681 tttaagagcc ggcttgatta aggcggagcg tattggaaag tacacatatt acaaaagaga
     7741 tgaagaagcc attgggaaac ttgctgactt tcttaaaaca gagatataaa aataaacatc
     7801 aaaagatgtt tatttttaca ccatacatat cgacatatta cgatgtgttt attttttata
     7861 ataacatatc gataattcgt gatatgttta ttaataatta aggagtgaat gttttatgtc
     7921 taacacttgg aaaatttata ttttagccat tgtcagcttt ttagttggaa cctcagagta
     7981 catcatttcc ggaattttgg atcaaattgc tcatactctc gggatcactt tagctgccgc
     8041 gggccagctt attaccattt tctcacttgt atatgctctt tctacacccg tacttatggc
     8101 gttgacagca agtatggata gacgcaaatt gatgatgtat gccctaggtt tgtttgtgtt
     8161 cggtaatgtc ctggcttttg tactgcctgg ttatggatgg tttattgcag cgcggatcat
     8221 tatggcgatg ggagcaggtg tggtggttgt caccgcatta acgattgccg ctaagattgc
     8281 atcggaaggg aagcagggaa gtgccatcgc tacggtcgtg atgggattta ccgcttcttt
     8341 aatcattggt gttccgcttg gaagaatgat agcagtagca ttaggctgga agtctgtatt
     8401 tggagcaatt gctttgttgg gattgatcgc aatggtcgtt attttcttta ctcttccgca
     8461 tactgaaggg gataagcctg tgcctttgct tcaacagctt gctcttttca aaaaacggaa
     8521 agtggctatg ggattatcaa tcactttctt ctggctcggg ggatattctg ttgcttacac
     8581 ttatttatcg ccgtatctct tgaacatctc aggtataaat ggcaagctgc tcagcggtgt
     8641 tttgcttata tttggaattg ccagtttggt tggatcgaag tttgggggat atagcaccga
     8701 taaatgggga gtacccttta cactcgttgg cgggatgacg ttgcatatcg tcacactgat
     8761 tcttctgtca cttgttactc attcctatat cggagtgttg gtgattctca tattatggtc
     8821 gtttgccgca tggtccaccg gtccgacaca gcaatttcac ctggctacaa tagaaccgga
     8881 aatgtctggt gttttgctta gcatgaatca gtcaatgatg caattcgcca tggcggtcgg
     8941 cgcaggaata ggaggggttt ttgtggaaaa cgtatcattg gcctcgatta cctgggttgg
     9001 tgcgttaggg gttatgattg ccattattgc atcattgctg attttcaatt cgcaaccgaa
     9061 acaagcgcta aaagatatca atcaataatt tcgaaagatc taacatccgc tcgttataca
     9121 agcgggtgtt ttttataagc gttcaaagtc agtccatgca tgagccttcc aagggccgac
     9181 atcgttctgt atgtgtcgaa ggcgcactga agctgaaagg gatttcttaa ggctttgccg
     9241 ctgaagtacg gtacgattgc cttgatcgaa cactggaaac acaagagaac gtaaacctga
     9301 acatccgcgt aaacgtcaag gaagttgcca cttagggagt aaacacttgc atcatctcgc
     9361 tgaaaggcct agacaatgcg gatgacatat tcgtattgcc ggaagtaaac acagcgcttg
     9421 ctctgtttcc gttgtcgatt gcagctgatt gcttactaat gctgccctgc atctcggttg
     9481 tgatgtcgat aagcagcgta accttgcgaa gagtgttact gtggagtaag atgtttaacc
     9541 cctctggata ttttagccga aggggttttt agtacagata tttgatttaa attacaggag
     9601 acttcattca tttaaccaaa gtcattgctt tcttaatcac taaagtttat ttgaaaataa
     9661 tctcttgatt taatttcctc gaagagattt tttgtcaatc tattaggcat cagaattttt
     9721 ataacataat ggatcgtctt tttgacgttt tgtttataga acaagaaaat attcaaaaca
     9781 taagtggaaa attaggggtg agctcctgtt tttctcgaga ggatagcttg tcagcttttc
     9841 tatttttaaa gggttaaaat attctattta tactaattaa tgtaattttt aggataatat
     9901 acaaaatccc ccttacttcg acaattgcaa tctggtatta tcgtatcgca tgggagctat
     9961 gtcaatagac tctatgcaaa aattgagagg aggtttactt atgaaaagaa accaaaaaga
    10021 atgggaatct gtgagtaaaa aaggacttat gaagccggga ggtacttcga ttgtgaaagc
    10081 tgctggctgt atgggctgtt gggcctcgaa gagtattgct atgacacgtg tttgtgcact
    10141 tccgcatcct gctatgagag ctatttaaca tttgagaata gggagttgag cgtatttgct
    10201 tatactcctt attttctctt aagggggatt ttatatgtca tatgatcgtg ttaaagattt
    10261 tgatttgcca gagttagcgg ttcatttaca gcctcatggt gctgtaatga ttgatagaaa
    10321 aagtatgttt tatttcagac tcagtggacg tggagcacag ttggcgtttc tgttatcaaa
    10381 aaacaaaaat cttcataaaa cggcacgtat ttgggagatt atgaaaaaag aagagatgag
    10441 tgctgaccaa ttaaaagaag agcttagtgc ccatccattt acggaggctt ggacggaagg
    10501 gctgttagat cagcctttac acgtttcggg ttcgctagat tcatatttac ctattagttg
    10561 taccttgcag ttgacaaatg cttgtaattt aagctgttcg ttttgctatg ccagctcagg
    10621 taaaccatat cctgaggaac tatctagtga acaatggata ttggttatgc aaaagttagc
    10681 agcccatgga gttgctgata ttacgctgac cgggggtgaa gcaaagctga tcaaagggtt
    10741 taaagaatta gtcgttgttg caagttcgtt gtttaccaat gtgaatgtat ttagtaatgg
    10801 attgaactgg cgagatgaag aagttgaatt acttagtcac ttaggcaatg tttctgtaca
    10861 gattagtatt gatggtatgg ataatacaca tgaccaatta agaggcagaa aaggcggctt
    10921 taaagaaagt atgaatacca ttaaaaaatt atcagaagca aacattccag tgattgtcgc
    10981 tatgaccatt aatgagtcca atgctgatga agtatcagat gtggtggagc aatgtgccaa
    11041 tgcgggtgct tttatctttc gtgcaggaaa aacgttatct gttggacgtg cgacagaagg
    11101 ctttaaggct ttggatattg attttgaaga aatggttcaa atacagctta gggaagcacg
    11161 tcataaatgg ggagatcgcc tgaacataat tgattgggag cacgaagaga gttcgttcac
    11221 aacagatttt tgtacaccag gatatcttgc ttggtatata agagcagatg gatacgtaac
    11281 tccttgccaa ttagaagatt tgccgctagg gcatatttta gaagatagca tggctgacat
    11341 tggttcacct gctcgtttgc ttcagttaaa atgtgaagca aaaaattgca aatgtatagg
    11401 gaaaattgag ctatctgaac cggacttacc ttttcaaaaa gaagtcaagg cagggattca
    11461 ggaatgaata gtctatcatt ggtgttctgg agtattttag cagttgttgg attactgtta
    11521 tttattaaat tcaaaccccc aacaattgct tcactactct taagcaaaga tgaggcaaaa
    11581 gaaataagca ttcaatttat aaaagagttt gttgggatag aagtagagaa ctgggatttt
    11641 tattcagtat attggtatga ccacgataca gtaaataaac ttcatcactt aggcatactt
    11701 aagaaaaata gaaaggtttt atatgatgtt gggttggtcg aatcatggag agtccgtttc
    11761 gttcaccaga atcaatcatt tgtagttggt gtcaatgcca atcgagaaat cacttttttt
    11821 tatgcggatg ttccgaaaaa aaccctttcg gggaagtttg aacaagtttc tccagagaca
    11881 ctcaagcaga ggttaatggc ttcacctgat ggactttggt ctagagcaaa tatgactggt
    11941 actggtaaaa aagaggagga ttttcgcgag gtcagtactt attggtatat agcggaagcg
    12001 ggagatattc ggctcaaagt gactgttgaa ttacagggcg gccgaatttc ttatattggt
    12061 actgaacaag aaatactaac agatcaaatg agtaaagtca ttcgagatga acaagtggaa
    12121 tcgacattcg gagtatctgg tatgctgggt tcagctttag cgatgatcct tgcgattctc
    12181 atccttgtat ttatggatgt gcaaacaagc ataatcttca gtcttgttct gggtttgttg
    12241 attataatat gccagtcatt gacgctgaaa gaagatattc aattaacaat tgtaaatgct
    12301 tatgatgcaa gaatgagtgt caaaacggtc agtttattag gtattttgtc tacacttctt
    12361 acaggattat taacaggatt tgtagtattt atatgttcat tggcaggaaa tgcgcttgct
    12421 ggtgattttg gatggaaaac gtttgaacaa ccaatagttc agattttcta tggaatagga
    12481 gcagggctca ttagtttagg agtgacttct ctgctgttta acttattgga gaaaaagcaa
    12541 tatttacgaa tttcacctga gctttctaac cgaactgtct ttctatcagg ttttaccttt
    12601 aggcaaggat tgaatatgag catacaaagt tcaattggag aagaggtcat ctatcggcta
    12661 ttaatgattc cagtcatttg gtggatgagt ggaaatatcc tcatctccat tattgtatct
    12721 tcctttttat gggcggtgat gcaccaagta actggatatg acccaaggtg gatacgttgg
    12781 ctgcatctat ttatattcgg ttgctttctg ggagttctct tcatcaaatt tggttttatt
    12841 tgtgtattag tagctcattt cattcataat ttagtactcg tctgtatgcc gctgtggcag
    12901 ttcaagcttc agaaacatat gcatcatgat cagccaaagc atacttcact ctaatgatta
    12961 ggagaagatt tgatgcaatt gatgcaagta caaaatttaa gcaaatgcta tcgaaatggt
    13021 gatggggttg aacatttgtc tttctcaatt caacgaggag aaatcgtggc gctattgggg
    13081 ccaaatggag ctggaaaaac aacgacaatt cgatgtttga caggtctcta taagccggat
    13141 aaaggagata tcctcattga gggttctcct ccaggagata taaatgttca aaaaaaagtc
    13201 gcgcttattc ctgatcagcc atatttgtat cccgctttaa ctgctgctga acatattcag
    13261 tttagggcaa gaggatatca tccaggtaaa aaagatgtaa aagaaagggt ttatcatgca
    13321 ttgaaggaag tgcacttgga ggagaaagca aaccaattgt gtggtcagct gtcaagaggc
    13381 caaaagcagc gggttgtcct ggcgggggcg attgttcaag acgctttgct gtatatatta
    13441 gacgaaccga ctgtgggcct tgatatccca tcaaaacagt ggctctctaa ctggttaaaa
    13501 actaaaaccg atcaagggtg ttcagcattt gtatcaactc atagtctaga gtttgttata
    13561 gagacagcag acagggtgat attaattaga gacggcaaac tcatgcagga tttgtatgtt
    13621 cctcaattcg aagaagaaca agcggaatgg agaaaagaag tgattcgtct tctaggggaa
    13681 tggtcagatg aataatatca tttctttttt atggcttcag tcaaaaaggc gttttgtaag
    13741 tcaaggtcag gaaaaaaaaa tgcctttttt gatcatgctc ctttttgttg gggccatcgg
    13801 atttcaagta agttttgttt ctagatctac gacatgggat atgagtattg ctggttgggt
    13861 acttacaggt gtttttatcc tttatacggc atttggactt ttttcaaatc gattaccaag
    13921 tcaaatggca gatattatat ggctttatgg cactgccaca tctttttcaa aagttgtgta
    13981 tagtgtttta tttttcagcg tcacttggaa ggcgttgctt tggatcatct cagccatatt
    14041 cggtgatgta ttaattgtgc ttctgtctgg tgatcatatc aatttattag gtcgatccat
    14101 aatttttgta gggctctttt ttatcgctga agtgtggttg atgtcggtct cttgtgccag
    14161 aacagtgaag aaaatgaaaa gggtatacgt tttagtcttt cttctaatgt taggcattta
    14221 ctccatatgt ctttatcact tcttctttct ccaacattca tctgggatat gggagagcat
    14281 tgcccgtttt attagtggcg ttggattagt gtttgataca ttgtcaccgt tgtatgtggt
    14341 tgtatttatt gggatcatca cagtctcttt tatgacaatt gcttttacga gcagtcaggt
    14401 agaaatgaag gaatcgttgg tgaaagaagc tgaattctgg gaggaatttc aagaacgtca
    14461 atttggttca ggtcaaatta tacagaaacc aaaaacgact tggtggggct tgcaaggtct
    14521 aaatggcatt tggtcttttc tgtggttgga actgttgctt tttaaaaaat atttattttt
    14581 tcatagcatt catacggtca tgctcagtgg cgtcttttat gtcgtcattt tcatgtatcc
    14641 agaatggttt tatcttcttt tctttcttat cgtctcggca gtcatgttaa gttcctatta
    14701 ttcaggaatt gtcagacatt ctcaatcagg cacccttcat ttattccccg gtgccctttg
    14761 gaaaaaaatc attattctag agctgacgaa tacagtctgg ttgtatattc tttactgtgt
    14821 ctctattact tttatggcag ttgggaattt agtttattgg tatatatatg gcttagggat
    14881 atatatatgg ttcatgacaa taaggctttt tgcttttacc catacaaacc gaaacgatcc
    14941 taggctttca ttgcctcaat actataagtc attttttatg gcattaggcc tgagcggcat
    15001 ttgtttgtat gtcattcatt tattgactgc tgactggtat acattagtgg tggttgtctg
    15061 tatagggagc ctaagttggt gcctgtttta tcgtttcaga tagtggttat gtagagttat
    15121 tgttttaaaa cgaggagaga ggctctttta tgaattcaaa tggtgataaa ttgtcgttat
    15181 ctgttcagaa tttagcgaat acaaatgaga tcacaattgt tcaagcgata ggtgagctaa
    15241 agaaatcggg aaaagatgca ataccagttt tggttgaggc cttaaaagag gaaggctctt
    15301 tgtgtaatat tgctgcagct gttttaggtg agtttgggga agacgcgagt gaagcagcgg
    15361 aggagctatc atgtttatta aaaagtcatg cggaagatac aagaatggca gcggcgattt
    15421 cattaatgag aatcgggaag cccagtctgc cctttgtcat caaaatcgct caagaaagtg
    15481 aagggcaatc gtgcttttgg gcatcttggt gtattgcatg gattgatccg tcttgcattg
    15541 aacctaagat gtataaatgt ctaaaatacg agcatgaaca tccttcagga atagttgctc
    15601 cgtttgcggc tgaagaggca ttaggaaagc tgattgcttt tcagctgaaa gataaggagg
    15661 actgaaagga tgaaagatga acaaatgttg actgaatggc caagtcattt accatggttg
    15721 aatcaatcac agaatgattt tacatttcca agtgacacat atcttcttct ttatttttgg
    15781 tcaatgagct gtccacactg tcaccaatta acagacaaag tccttcaaga tataaaggat
    15841 atgaatgtga aagtaatcgg agtacatgtc ccttatatag aagaagagaa atctatggag
    15901 gttgtcttga cgtatgctct tgatagggga ctagctattc cgattgtatt agaccaaaac
    15961 tatgagatcg tcacaacttg tcacgtacaa ggcatcccca gcttttgtct attaagtcaa
    16021 tacggtcaga tcattactaa aacgatggga gatgttggtt gggataagat gttaaaaaag
    16081 attgcaggct tgtgaaattt tccgtcttgt atgtgcgaca aacggttgaa tattatgatg
    16141 aaacggtcct tcctataagc aggaaggttt tttaatgaaa tattttttta ttagtaggta
    16201 aattcatcaa atgttctgct atgctccaaa tgtacacctt tccgtaaggg caaagttaaa
    16261 tgtgaaaata aaactgttcc aaagttaatc agttatttat tttcataccg tatcctttca
    16321 gtatcacggt gaaaggagca tcatatgaaa acattatgga aagtcctaaa aattgttttt
    16381 gtcagcttgg ctgctttggt tttgcttgta tccgtctcgg tatttattta tcaccatttc
    16441 cagctaaata aggaggcggc actgctgaac tgaaaggtaa aggcatagta gtcgatgttg
    16501 acgggaaaaa gatgaatgtg tatctagagg gaagcgggaa ggatacgttt gtgtttatgt
    16561 ccggttcggg gattgctgcg cctgcttatg aaatgaaggg gctgtacagc aagttttcaa
    16621 aagaaaataa gattgctgtt gtagatcggg caggttatgg atacagtgaa gtgtctcacg
    16681 atgacagaga tattgatacg gtattggaac agacgaggaa agcgcttatg aaaagcggaa
    16741 ataagcctcc ttatatttta atgcctcatt cgatatccgg gattgaagcg atgtattggg
    16801 cacagaaata tcctaaggaa atcaaggcca ttattgcgat ggatattgga ttgccccagc
    16861 agtacgtcac gtataaattg agcggagttg acagattgaa agtgagaggg ttccacttgt
    16921 taacgtcgat tggttttcat cggtttatgc cttccgctgt atataatcct gaggtgattc
    16981 ggcagtcgtt tttaactgat gaagaaaaag aaatctataa agccattaac tttaagcaat
    17041 tttttaatgc agatatggag catgagcttt tacagtctta ccaaaacggc agcaaatctg
    17101 tgaatctgcc ggcaccaaag gaaactcccg tcttgatttt agatgcggtc tctgaccaaa
    17161 atagacattc aaagtatgct atacaaaccc gaaaagacta tgaagcgttt gcggctcaat
    17221 tcaatactgc cgatataaag gaactgaggg gaacacacag tatttattta tatcagcctg
    17281 atcaaatata taaactgtcc atggagttta tgagaaaggt ttgctaggat gaagggttat
    17341 catattttaa tcgtggaaga cgatgtgatg attggtgatt tgctgcaaaa gattttgcag
    17401 cgtgagggat atcgtgtgat atggaaaaca gatggagcgg atgtgctttc ggtgattcag
    17461 aaggtggatt tggtcattat ggatgtgatg ctgccgggtg aagacgggta tcaaatgtct
    17521 gcaaaaatca aaaagctggg gctgggcatt ccggttattt ttctctcagc ccgcaatgac
    17581 atggacagca agcttcaagg tttgcagatc ggcgaggatt atatggtaaa gccctttgat
    17641 ccgagagagc tgctattaag aatgcggaat atgcttgagc atcattatgg gacctttacg
    17701 caaatcaaac atttgtatat tgatgcggta acgaaaaaag tgttcaatga aagcctgtat
    17761 gatgaggtat tatttactgc gattgagcgg aaaattttct tttatttata tgaaaataga
    17821 gacagtatcc tgacaaagga acatttcttt gaatatctat ggcagctcga agatagaaac
    17881 ccgaatattg tcaatgtgca tattaaaaaa atcagagcta aaatcaatga tcaagcgggt
    17941 gagatgattg aaaatatata tggagaaggg tatcggctga ataccgttgt gaagaaatga
    18001 agctcaagac aaaatatcag ttgttattgt ttacggccgt cattagtgtt ccgatgctat
    18061 tgctggcggt cagtgttttg atgtcggtga tttatgacag catgtttaaa ccgatgaatc
    18121 atggtatgcc ctttcacagg tcgtttgcat acccggcaat gatcgttgta tttttgatat
    18181 cactcttatt gttagctttt ttattttcaa agtcgattca ttctctgttg cataaaatca
    18241 atctattaaa tcaaaccatt cggcatttgg cgagtgatca aagggtgccc gataaaattg
    18301 aagtgaagcg tgctgatgaa atcggggaac tgatcaagtc agtcaatttg ttaattgaac
    18361 ggacgacata tcgtgaactg gagctgagac agcaggagga aatcaaaaag gagcttttgc
    18421 aaaaactgcg gcatgacatt aatacacctt taacggctct caggctgcag ttattttatt
    18481 tggaagacca atgtcatggt caggctgtat tcgaatcatt gtatcagcaa atcgaatata
    18541 tctcggaatt aaccaatgaa ttcaatctat attccgctga gacgctggaa agctcttata
    18601 ttgtaaatga agaagtgcgt ctaaacgagc tattagaaac agcagtgaaa aagtgggatt
    18661 atttatacag tatgagtggg attgagctgc actataaggc ggcagatcaa gatgtgatat
    18721 ggatgagcaa cgcgttatgg atgcaaaggc tgtttgataa tatttttcaa aatacgttaa
    18781 agcattcaaa agctgaaaag atggaagtca cgattgaaca tgacaatgtt tttattcgtg
    18841 atgacggtat tggacttgat cggaatgaga gcagtgaggg acttgggtta aagattattg
    18901 aggatacatg caggctgctt gcgattactt atgagctgca tacaaatgat agcggaacgg
    18961 ggttcttgtt ttcaaaagag tgaccccgct gatgtttttc tttctcctat aaaatttata
    19021 taatagggag aaagaaatgg ggtgaacatc atatgtttaa aaaaatcatc aaaacgatta
    19081 agtacctctc aagcagttct agtgaccgat atcgcagaca ccggcattac agcagcagcc
    19141 ggcgcagaca ttatcgcagc tacagcagca gctcgggcaa aagaagacac tacgaccgtt
    19201 atggcggcag tcatcgttac aaacgccgga gctacagcag cagttaatcc aaaaaaagtt
    19261 cttgttccgc ttttgggaca agggtttttt tatgtgatcg attgaatggc ccggtttaga
    19321 tcctcgcgaa tggaagcggt gtgctgatac tccttatcaa tgcccaataa tcttttcagc
    19381 agcagggtta cttcctttgt cagtgttaat tcctccagcc aagtgccgtt tttcttcttt
    19441 tttcctttat attgagagta cagcaggaat aacagcgttt ctccgagatc gaagaagtca
    19501 tcctgttttc gtacctttat ttcctccatt tcttcaagag tcaattgttt ggcaaggccg
    19561 aaatcgagga ggcagagcct gccgtcattg atgatgatat taggcgtcct gatgtcgctg
    19621 tggaagataa ggcgatcatg caggtattct ataatctcaa gcagctgcga aatcagttgt
    19681 aacgccataa gctctgtgaa cggctgtttt cgaaaaaata ataattcttc tatattctct
    19741 ccctcaatga actgcatgac ataataagcc tgtccgtcta tgatgaactc atctatgaag
    19801 cccggaattt gcgggtggtg aatgcttttg agcagtttta tttcctgttg gaatcggact
    19861 ttttcttttt ccttttttgc ttttgtcggc cgaagctgtt ttaagacata aggtgtttga
    19921 gttaggatat cggtgcacaa ataaaccaaa ccgtagcctc ccataccgag gcactcttcg
    19981 attttgtatt gatgatttaa gataacgccg ttctttagag ggcggtcaaa aagcagtttt
    20041 tttagaagtt ttaatgccat gtctgcactt cccttggttg tactgactat agtttacctt
    20101 ctagacggag aataaaaaag agccggataa ccggctcggt ataagttaaa actgctttgt
    20161 tacgtcgtat tcataatcta tttttgcttt aacattgctc atcgtcgatc tggcagtcgc
    20221 taatgtatta tatttaaaac tccatacctt tgccacactg agttgatccg acaaagagat
    20281 atcataagac cctgaagttg agctgtttac aagggcacga cgccattcgt tattttcgtt
    20341 cgtcatgatc aggtggcgtg tatttccctg gcttggtgtt tgagtggcgg ttgtttgaac
    20401 tctggttaca atggcatcac gcggtatccc ggattggttt gttaaatcaa ccttgatcac
    20461 gctggagtca gagcctgagg ggctaaggct tgtatttcct ttattttcag caacgccgct
    20521 gaattggaat gttccgctgc ctgatttgat tcggtcttca attgaaagcg taaagtacat
    20581 gtttccagta taggtgcctc gtgacacttt cacataaaag gtatctgtcg tgttttgggc
    20641 gtctgcattt gcataaataa aagaagaaaa cgtattaggg ttaatgactt ctgtcccttg
    20701 agaaacaggt attctattct tatcataaat ttcaattttc atccctgtat acgcgctctg
    20761 gtatgtactc ctcacgtata ctttttctcc cttattagcc gtaaaagtga aataggcttc
    20821 atcttgacca gcttccagta ttgttgtatc gatattttta tatttccaat aaccgatcgg
    20881 cattgcggta tcaaatgaat tgtttcctgt gatagcagtg actccgacag ctgatgccga
    20941 atacgtaaag gtgaataaga cagacagcat aacagcgaat ggaataagcc attttttcac
    21001 catgcaaaca acctcctttt atttccatca tacataataa cgatttaggt gtaaataaat
    21061 gttttttgag gttaatatat acattatatt tgccgataaa aaagaataag agagaatact
    21121 cgggagggaa ttcaatgcgt ctgaatcggc aatttatccg cactcagctg atggcacaga
    21181 acatattgag caagaatgcg cctgccaaac gggagaatgc gactgaaaat ccagcggcag
    21241 ttctggaaaa ggcatacagc aggcttaagt cacaatcttc aactggggga atcaatcagt
    21301 tcaattattc taaaaccagc gtgtcgggaa acagcggggc gttcagcaaa gtgtatcaat
    21361 cagcgaatga tcgaacagtg acagacacag gggaagaaac agtgattcaa tcccaaaacc
    21421 cctatgaatc tgagagtgat atcagaatca aaatactaga tgaaaaatac agcaggatga
    21481 atgcaattaa taaaacaaag tctgatccat taggctatat taaggataag taccaaaatt
    21541 caaagtctcc ttatttcaga agtgatctgt cagctgcaga aagacaggcc gcatacgata
    21601 atgaaacaga atggttattc aaaggcaagg cgcaaaacta taacctccag gatgctgcgt
    21661 ttcggaatgt cacatttcat ggggaagtgg aagctgagaa tgaaaaggtg tatcagcggg
    21721 gacaggttaa ccagcagctg caagtgctgt tgaatcgaaa ccatattcat attccagagg
    21781 ggacagagct gacgtttaca atcacaccga ttgactatca ggtgcgggta agcgggacag
    21841 acgatcagga tctgatcaag cagattgagc aagtgctgca atctggagac aacagcaaag
    21901 aactattttt gcacatcatg aaaagccaaa gcagtgattc aacacaattt tccgaagagg
    21961 cctatcaaaa gtatcaggca gctcgtgaga tgtacgaagt cactggctac catttgaagg
    22021 atttagaagt cattgatgga cggtacgtca cgcctgatgg acgtgactta atagatgtat
    22081 ataaggaaga gcttgaaaaa gatccagtgc agaagcaaac ggcttcttat gctatatctt
    22141 actatcgttc agagctcagt aaaatcgtgg aagccgggta taatgccatt ccggatttca
    22201 tcctatcaat tgattacagc aatggatctc tgagagatgt gggacaaagc aagagctatg
    22261 ggaccggaga taccgggtgg cttgaagcat taaagcgtca aacgggtgtg aattattagg
    22321 taagctgttc atgtagaaca gcttattttt tatgagaatc taaggggtgt attaatttaa
    22381 atattcaaat aattttatta tttttatata aaagatttta aaagaagtga acgattcaaa
    22441 actctgaaca aaggtgttta cctgaaaaaa acaattgtat tttccagaga aatttattat
    22501 gatgaaataa gtaatttagg agattatata acaattttag gtttgaattt tctgattttt
    22561 atcactgatt catgtgaagg caagcaggtc tgctgttttc tcatttatga gtattttgtt
    22621 aggaggagga agaggagtgg caaataaaga attaaagagg ggcctgggcg cgcgccatat
    22681 tcagatgatc gccttgggcg gtacaatcgg tgttggcttg tttatgggtt ctgccagcac
    22741 gatttcatgg actggcccat ctgtccttct ggcttatgca atatgcggaa tttttatctt
    22801 ttttattatg cgtgcgatgg gtgaaatgct gtatgtcgag ccgagcacag gctcttttgc
    22861 gacgttcggc catcaatata ttcatccgat ggcaggttat ataacagcat ggagcaactg
    22921 gttccagtgg attatcgtcg gcatgtcaga aatt
//
