LOCUS       c00002_gnlPro..        15323 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OGIMCKKF_2.
ACCESSION   c00002_gnlPro..
VERSION     c00002_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-05-01 01:47:48
            Original ID  :: gnl|Prokka|OGIMCKKF_2
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15323
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..342
                     /locus_tag="ctg2_1"
                     /transl_table=11
                     /translation="TRAQCLLTPGHTAGGMCYLFSESIFTGDTVFTEGCGICEDDGSSA
                     EEMFDSIQRIKSEVSPHVRVYPGHSFGKLPGHSIKDLYQHNIYFQIDKKEYFVKFRTRK
                     NQKGIFDFK"
     protocluster    1..15323
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[5637:15323]"
                     /cutoff="10000"
                     /detection_rule="(not (EC1_2-faecali or baiH or baiCD or
                     ECH1_Enoyl_CoA_DH1 or ECH1_Enoyl_CoA_DH2 or
                     ECH1_Enoyl_CoA_DH3 or ECH1_Enoyl_CoA_DH4 or POR or POR_N or
                     PFOR_II) and minimum(4, [AcetylCoA_hyd_C, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, EC1_2-faecali, ECH1_8_CARC, ECH_1, ECH_2,
                     HBT, HCDH, HCDH_N, Thiolase_C, Thiolase_N,
                     ketoacyl-synt]))"
                     /neighbourhood="10000"
                     /product="fatty_acids-unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      5638..15323
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(not (EC1_2-faecali or baiH or baiCD or
                     ECH1_Enoyl_CoA_DH1 or ECH1_Enoyl_CoA_DH2 or
                     ECH1_Enoyl_CoA_DH3 or ECH1_Enoyl_CoA_DH4 or POR or POR_N or
                     PFOR_II) and minimum(4, [AcetylCoA_hyd_C, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, EC1_2-faecali, ECH1_8_CARC, ECH_1, ECH_2,
                     HBT, HCDH, HCDH_N, Thiolase_C, Thiolase_N,
                     ketoacyl-synt]))"
                     /neighbourhood="10000"
                     /product="fatty_acids-unassigned"
                     /protocluster_number="1"
     cand_cluster    1..15323
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(not (EC1_2-faecali or baiH or baiCD or
                     ECH1_Enoyl_CoA_DH1 or ECH1_Enoyl_CoA_DH2 or
                     ECH1_Enoyl_CoA_DH3 or ECH1_Enoyl_CoA_DH4 or POR or POR_N or
                     PFOR_II) and minimum(4, [AcetylCoA_hyd_C, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, EC1_2-faecali, ECH1_8_CARC, ECH_1, ECH_2,
                     HBT, HCDH, HCDH_N, Thiolase_C, Thiolase_N,
                     ketoacyl-synt]))"
                     /kind="single"
                     /product="fatty_acids-unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15323
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="fatty_acids-unassigned"
                     /region_number="1"
                     /rules="(not (EC1_2-faecali or baiH or baiCD or
                     ECH1_Enoyl_CoA_DH1 or ECH1_Enoyl_CoA_DH2 or
                     ECH1_Enoyl_CoA_DH3 or ECH1_Enoyl_CoA_DH4 or POR or POR_N or
                     PFOR_II) and minimum(4, [AcetylCoA_hyd_C, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, EC1_2-faecali, ECH1_8_CARC, ECH_1, ECH_2,
                     HBT, HCDH, HCDH_N, Thiolase_C, Thiolase_N,
                     ketoacyl-synt]))"
                     /tool="gutsmash"
     CDS             715..1581
                     /locus_tag="ctg2_2"
                     /transl_table=11
                     /translation="MITYVFPGQGSQKQGMGSGLFDEFKELTDQADEILGYSIKRLCLE
                     NPYSNLNKTQFTQPALYVVNALSYLKKIKDEEVKPDFVAGHSLGEYNALFAAEAFDFET
                     GLQLVRKRGELMSLISNGGMAAVMGLNEEQVAKALKEYHLHDVDIANVNAPYQIVISGK
                     KDEIEKAASLFETMTEVTMVLPLNVSGAFHSRYMNKAKEEFEEFLHAFYFSPPSIPVIS
                     NVYAKPYTYEFMKQTLADQINHSVKWTDSIRYLMKKGHMEFEEVGPGNVLTGLIHRIKK
                     DAEAMPS"
     CDS             2085..3059
                     /locus_tag="ctg2_3"
                     /transl_table=11
                     /translation="MNEPLVFMFSGQGSQYYHMGKELFKENTVFRQSMLEMDAIAARRI
                     GTSIVEEIYHSGKRVSDPFDSILFSHPAIFMIEYSLYKVLEDRGIYPDYVLGSSLGEFA
                     AAAVSGVSDAEDILDCILEQAIIIQNSCDKGKMLAILDKPQLLNDHPQLFGNSELISIN
                     YDSHFVISGEEDHIRKIMEDLKEKQILCQLLPVSYAFHSSLIDPAESAYAEFLRSKSFK
                     KPSIPIVSSLTGSCLHVMDENFFWNAVRKPMMFREAIRYLESQHTCKFIDLGPSGTLAA
                     FVKQLIPGDSADRCCSIITPFHQELKNLNTVEYFRTPERKFTR"
     CDS             3056..5359
                     /locus_tag="ctg2_4"
                     /transl_table=11
                     /translation="MITYVFPGQGSQQKGMGQGLFEQYQHLTDQADQILGYSIEKLCTE
                     KSYLDVNHTEYTQPALYVVNALSYLKRVEETGRKPDFAAGHSLGEYNALMAAGAFDFET
                     GLRLVKKRGELMGRITGGGMAAVIGLSKEQVTAVLEEHRLYDIDVANENTPRQIVISGP
                     KNEIEKARAVFENTKDVKLFHPLNVSGAFHSRYMNEAKQVFKQYIDSFQFAPLAIPVIS
                     NVYAEPYHQDRLKDTLSEQMDNTVKWTDSIRFLMGRGEMEFAEIGPGTVLTGLIHRIKN
                     EAEPLTYIPKKNPAISAHLKEQRNVQAGITAESLGSAEFKQDYHLTYAYLAGGMYRGIA
                     SKEMVVKLSRAGMMGFFGTGGLSLKEVEDAIHAIQGELGKGQAYGINLVHNMKHTESEE
                     KMIDLLLRNQVSIVEASAFLSVTPALVRYRAKGVKRNQNGDVICSNRLIAKISRPEVAE
                     SFLSPAPENMLQKLLRENKITMNEAELLRCIPMADDICVEADSGGHTDGGVAYSLMPAM
                     TSLRDEMMKKYQFRKKIRVGAAGGIGTPEAAMAAFMLGADFILTGSINQCTVEAATSDK
                     VKDLLQQMNVQDTAYAPAGDMFESGSKVQVLKKGVFFPARANKLYELYQRYGSIRELDA
                     KMLAQLEEKYFKRSIEDIYKDIALHYPAADIEKAEQNPKHKMALIFRWYFRYSSKLAIS
                     GSEHSKVDYQIHCGPALGAFNQWVKGSQFENWRNRHVDEIGKKLMTETAVLLHERMQSM
                     YQPSHATDNIKIKV"
     CDS             5412..5660
                     /locus_tag="ctg2_5"
                     /transl_table=11
                     /translation="MDKQRIFEVLITNICEVLPELDGHRFEPEDQLVELGADSVDRAEI
                     ITMVLEDLSLKIPRIELSGVKNIGELAEVLYDKVQSA"
     CDS             5638..6885
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Ketoacyl-synt_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_6"
                     /sec_met_domain="ketoacyl-synt (E-value: 1.4e-44, bitscore:
                     141.9, seeds: 81, tool: rule-based-clusters)"
                     /sec_met_domain="Ketoacyl-synt_C (E-value: 8.8e-31,
                     bitscore: 95.9, seeds: 85, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKCNLPEVVVTGVGVTASIGQGKEDFASSLLSGRHAFDVMKRSG
                     RQKDSRFIGAEIASLSYPDRLSKKMLRKASFSSRAALVTLTEAWEEAELDDADSSRIGL
                     VVGGSNFQQRENFEVYERYQDRSGFISPAYGLSFMDSDLCGICTDQFGITGLAYTVGGA
                     SASGQLAVIHAIQQVLSGEVDTCIALGALMDLSYMECEALRALGAMGTDKYADEPEKAC
                     RPFDQNRDGFIYGESCGALVIERKETALRRGLKPYAALSGWSIKLDGNRNPDPSLEGEI
                     HVIQKALERARLLPEDIDYINPHGTGSFIGDEIELKALRACRLSHAYINATKSITGHGL
                     SAAGIVEIISVLLQMKKSALHPSRNLDHPIDDSFHWVNEKSISYRIKNALSLSMGFGGM
                     NTAVCIQNIEKCGGES"
     CDS             6886..8148
                     /locus_tag="ctg2_7"
                     /transl_table=11
                     /translation="MVSAGIEAMNVFGGTAYLDVMELAKYRHLDTARFENLLMKEKAVA
                     LPYEDPVTFGVNAAKPIIDALSEAEKDRIELLITCSESGIDFGKSLSTYIHEYLGLNRN
                     CRLFEVKQACYSGTAGFQMAVNFILSQTSPGAKALVIASDISRFLIAEGGDALSEDWSY
                     AEPSAGAGAVAVLVGENPEVFQIDPGANGYYGYEVMDTCRPIPDSEAGDSDLSLMSYLD
                     CCEQTFLEYQKRVPGANYQDTFQYLAYHTPFGGMVKGAHRTMMRKVAKVKTSGIETDFL
                     TRVKPGLNYCQRVGNIMGAALFLALASTIDQGRFDTPKRIGCFSYGSGCCSEFYSGITT
                     PQGQERQRTFGIEKHLDRRYQLSMEEYELLFKGSGMVRFGTRNVKLDFEMIPGIMQSTQ
                     EKPRLFLEEISEFHRKYRWIS"
     CDS             8145..8915
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: ECH_1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_8"
                     /sec_met_domain="ECH_1 (E-value: 1.1e-89, bitscore: 289.4,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VTYQTIKVRFQASVCYITFHRPEANNTINDTLIEECLQVLNQCET
                     STVTVVVLEGLPEVFCFGADFQEIYQEMKRGRKQASSQEPLYDLWMKLQTGPYVTISHV
                     RGKVNAGGLGFVSATDIAIADQTASFSLSELLFGLYPACVLPFLIRRIGRQKAHYMTLM
                     TKPISVQEASEWGLIDAFDAESDVLLRKHLLRLRRLNKKGIAHYKQFMSSLDHQVSRAK
                     ATALTANQNMFSDPQNQMGIIRYVETGQFPWEDQ"
     CDS             8947..9696
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: ECH_1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_9"
                     /sec_met_domain="ECH_1 (E-value: 4.9e-82, bitscore: 264.4,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHSVVELIEIESAIIQVKMQDRTHKNAFSQELTDGLIQAFKYIR
                     QNPKYKAVILTGYDNYFASGGTQEGLLRIQQGLTKFTDDNLYSLALDCEIPVIAAMQGH
                     GIGGGFVMGLFADIVILSRESVYTANFMKYGFTPGMGATFIVPKKLGFSLSQEILLNAG
                     SYRGADLEKRGVPFKVLPRAEVLDYAVELAQELAEKPRNSLVTLKDHLVASLRDQLPRV
                     IEQELVMHEKTFHHEEVKSRIKGLYGN"
     CDS             9741..15323
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:AMP-binding enzyme (Score: 357.4; E-value:
                     2.8e-109)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_10"
                     /sec_met_domain="AMP-binding (E-value: 4.6e-110, bitscore:
                     357.4, seeds: 145, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding_C (E-value: 5.4e-16, bitscore:
                     48.9, seeds: 272, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 1.3e-29, bitscore:
                     92.9, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRNNDNIRILANPSVSHGEPLHISEKQPATIPEVLYRTAAELGDT
                     KGIIYLQPDGTEVYQSYRRLWDDGLRIAKGLRQSGLKAKQSVILQLGDNSQLLPAFWGC
                     VLTGGVPAPLAVPPTYAESSSGTQKLKDAWTLLDKPAVITDRGMHQEMLDWAKEQGLEG
                     FRAIVVEDLLSAEADTDWHQSSPEDLALLLLTSGSTGTPKAVMLNHRNIMSMVKGIIQM
                     QGFTREDITFNWMPFDHVGGIGMLHLRDVYLGCQEINVSSETILMEPLKWLDWIDHYRA
                     SVTWAPNFAFGLVTDFAEEIKDRKWDLSSMRYMLNGGEAMVAKVGRRILELLEPHGLPA
                     DAIRPAWGMSETSSGVIFSHEFTRAGTSDDDHFVEIGSPIPGFSMRIVNDHNELVEEGE
                     IGRFQVSGLSVTSGYYQRPDLNESVFTEDGWFETGDLGFLRNGRLTITGRTKDAIIING
                     INYYSHAIESAVEELSEIETSYTAACAVRLGQNSTDQLAIFFVTSAKLNDEQMSQLLRN
                     IQSHVSQVIGVTPEYLLPVQKEEIPKTAIGKIQRTQLKTSFENGEFDHLLHKPNRMNDA
                     VQDEEMQQADHVKRVREEIQEHLLTCLTEELHVSRDWVEPNANIQSLGVNSIKMMKLIR
                     SIEKNYHIKLTAREIHQYPTIERLASYLSEHEDLSSSSADKKGTDTYKTEPERSQATFQ
                     PLSEVQKGLWTLQKMSPEKSAYHVPLCFKFSSGLHLEALQQAFGLVLNQHPILKHVIQE
                     KDGVPFLKNEPALSIEIKTENISSMKESDIPAFLRKKVKEPYVKENSPLVRVMSFSRSE
                     QEHFLLVVIHHLIFDGVSSVTFIHSLFDTYQLLLKGQQPEIAVSPAIYHDFAAWEKNML
                     AGKDGVKHRTYWQKQLSGTLPNLQLPKVSASSVSEFREDTYTRRLSSGFMNQVRMFAKE
                     HSVNVTTVFLSCYMMLLGRYTGQKEQIVGMPAMVRPEERFDDAIGHFLNMLPIRSELNP
                     ADTFSSFISKLQLTILDGLDHAAYPFPKMVRDLNIPRSQAGSPVFQTAFFYQNFLQSGS
                     YQSLLSRYADFFSVDYVEYIHQEGEYELVFELWETEEKMELNIKYNTGLFDAASISAMF
                     DHFVYVTEQAMLNPSQPLKEYSLLPEAEKQMILKTWNATGKTYPYITFHELFEQQAKKT
                     PDRAAVSYEGQTLTYRELDEKSTQLAIYLQAHGVGPDRLAGIYVDRSLDMLVGLLAILK
                     AGGAYVPLDPSYPAERLEYMLEDSEVFITLTTSELVNTLSWNGVTTALLDQDWDEIAQT
                     ASDRKVLTRTVTPENLAYVIYTSGSTGKPKGVMIPHKALTNFLVSMGETPGLTAEDKML
                     AVTTYCFDIAALELFLPLIKGAHCYICQTEHTKDVEKLKRDIRAIKPTVMQATPATWKM
                     LFYSGWENEESVKILCGGEALPETLKRYFLHTGSEAWNMFGPTETTIWSAVQRINVECS
                     HATIGRPIANTQIYITDSQLAPVPAGVPGELCIAGDGVAKGYYKKEELTDSRFIDNPFE
                     PGSKLYRTGDMARWLTGGRIEYIGRIDNQVKIRGFRIELGDIESRLSEHPGILECVVVA
                     DMDNLAAYYTAKHANASLTARELRHFVKNALPAYMVPSYFIQLDHMPLTPNGKIDRNSL
                     KNIDLSGEQLKQRQTSPKNIQDTVFTIWQEVLKTSDIEWDDGFFDVGGDSLLAVTVADR
                     IKHELSCEFSVTDLFEYSTIKNISQYITEQRMGNASDHMPTDPPAHIEDQSTEMSDLPD
                     YYDDSVAIIGISCEFPGAKNHDEFWENLRDGKESIAFFNKEELQRFGISKEIAENADYV
                     PAKASIEGKDRFDPSFFQISPKDAEFMDPQLRMLLTHSWKAIEDAG"
ORIGIN
        1 acaagagcac aatgccttct cacaccgggg catacagccg gcggaatgtg ttatttgttt
       61 tctgagagta tttttaccgg agatacggtg tttacagaag ggtgcggcat atgtgaggat
      121 gatggcagct ctgcggaaga gatgtttgat agtattcaaa gaataaagtc ggaggtttca
      181 ccccatgtac gggtgtatcc tggtcactca tttggcaaat tgcccggcca ttcgataaag
      241 gatctttatc agcataatat ttactttcaa attgataaga aagaatattt tgtgaaattt
      301 cgcactcgta aaaaccaaaa aggtattttt gattttaaat aatccttctg aatctattat
      361 cctatttttc ttcgaatatc taaatgattt ttattttcga aaatgattat atagaaggtg
      421 ttatttattt tgaaaactca tttgaaagaa aatgaagcgt attatcatga tatggcgccc
      481 tatacgtaat ccgggtcttt tttcttatgt tctgttatat ctcctgatcc tttattcctc
      541 aatggaaaaa agcagaaaaa caatcgagca aactgtagga aaaattaact tgacggataa
      601 tatttacaga ggttaccatc aacatgaaca tgctactatt tatccggtca tcactattat
      661 aaaatcatac agaagtgaaa cacatctact aatcggaagg gtggctttga gagaatgatc
      721 acatatgttt ttccaggtca gggttcacaa aaacagggaa tgggcagcgg cctattcgat
      781 gaatttaaag aactgacgga tcaggcagat gagatcttag gatattctat caaacgtctt
      841 tgcctggaaa atccttattc caatttaaac aaaacgcaat ttactcagcc ggcgttatat
      901 gtggtaaacg cactaagcta tctgaaaaaa atcaaggatg aagaagttaa acctgacttt
      961 gtcgccgggc acagcttggg tgaatacaat gcgttatttg cagctgaagc ctttgatttt
     1021 gagacaggtt tacagcttgt cagaaaaaga ggcgagctga tgagtctgat aagcaacggc
     1081 ggtatggcag ctgttatggg actaaatgaa gagcaggttg caaaggctct gaaagaatat
     1141 catttacatg atgttgatat cgctaatgtg aatgccccat atcaaattgt aatttcagga
     1201 aaaaaagatg agattgaaaa agccgcatct ctttttgaaa cgatgactga agttacaatg
     1261 gtactcccct taaacgtaag cggcgcgttt cattccagat acatgaataa ggcaaaagaa
     1321 gaatttgagg agttccttca tgccttttat ttttcgcctc cgtctatccc ggttatttct
     1381 aatgtgtatg ccaaaccgta tacatacgaa ttcatgaaac agacgctggc tgatcaaatt
     1441 aatcattcag tgaaatggac tgacagcata agatacttaa tgaaaaaagg ccatatggag
     1501 tttgaggagg tagggcctgg aaatgtttta actgggttaa ttcatcgcat aaagaaagat
     1561 gcggaagcaa tgcccagcta aagcatttgc ccctatggcc atgtatctca tcaatcaggt
     1621 ctaaacacag atttcctttc atttaaggta taaagtttta aagattcaat cgttcgattg
     1681 acactgtttc taattgaata actttatata ctgttacata aagaggctga taaattaagt
     1741 tagacatttg aactatgtca gccggtctgt caaaccatcg ctcccacatc tagatggtcc
     1801 attttttaac cgcacccacc aatcatagag tcgatgttct ttgctgatcc tgttatcatg
     1861 ttacatcaat tttgagatat caacatacat ctacgatcac gtcataaatg aaccgcatcc
     1921 agagcaccaa tagcaatcct tccaagttga atctccttta ctttttcaca tatgtctttt
     1981 ccatttatta atttcatttc aatcgctgct atgtgcttta acaacatgca tggaaatgag
     2041 aaatccaata gccgtcataa atataaaaaa agaaggttat acacatgaat gaaccgcttg
     2101 tttttatgtt ttccgggcaa ggttcccaat actatcacat ggggaaagaa ctatttaagg
     2161 aaaataccgt gtttcgccaa tctatgcttg aaatggatgc cattgcagca cggcgaatcg
     2221 gcacatccat tgttgaagaa atctaccatt caggtaaacg tgtgtcagat ccgtttgaca
     2281 gtattctttt ttcccacccc gccattttta tgattgagta ttccttatat aaggttttgg
     2341 aagacagggg aatttatcct gattacgtat tgggatcaag tctgggagaa ttcgcagcag
     2401 cggcagtttc tggtgtgtca gacgcagagg atatactgga ttgcatactt gaacaggcta
     2461 ttatcatcca gaattcctgc gataaaggaa aaatgctggc cattcttgac aaaccgcaat
     2521 tgctgaatga tcatccgcaa ctgtttggaa atagtgaact catttctatc aattatgatt
     2581 cgcacttcgt catttctggt gaagaagatc atataaggaa gattatggag gatttaaagg
     2641 agaagcagat tctttgccag ctgcttcctg tgtcctatgc ctttcattct tcgcttattg
     2701 atccggcaga gagtgcctat gcagaatttt taagatcaaa atcttttaaa aaaccgtcaa
     2761 taccgattgt atcgagctta acgggaagct gccttcacgt aatggacgag aatttctttt
     2821 ggaatgcggt cagaaagcca atgatgtttc gtgaagcgat tcgatatttg gaaagccagc
     2881 atacatgcaa gtttatcgat ttagggccat ccggcacctt agctgctttt gtgaaacagc
     2941 tgattccggg tgattcagct gaccgttgct gctcaatcat aacaccattt catcaggagc
     3001 tgaaaaatct gaatacggtt gagtatttcc gtacaccaga aaggaagttt acaagatgat
     3061 tacatatgtc tttccagggc aaggctccca gcaaaagggg atgggacaag ggctatttga
     3121 acagtatcag catttgacag atcaagcaga tcaaatattg ggctattcaa tagagaagct
     3181 atgtaccgaa aaatcatatc tggatgtaaa tcatactgaa tacacgcagc cggctttgta
     3241 tgttgttaat gcactcagtt acttgaagag agtggaggag accggcagaa aacctgattt
     3301 tgcggcagga cacagcttag gagaatacaa tgcgctgatg gcagccggtg catttgattt
     3361 tgaaaccgga ttaaggctcg tcaaaaaaag aggagaattg atgggacgaa ttacaggggg
     3421 cggaatggct gctgtgatcg gcctgagtaa ggaacaagtt acagccgttt tagaagagca
     3481 ccgtctttat gacattgatg tggcaaatga aaatacgccc cggcaaattg tgatttctgg
     3541 cccgaaaaac gagattgaaa aagctcgggc tgtttttgaa aacaccaagg atgtaaagct
     3601 gtttcatcca ttaaatgtga gcggagcttt tcattccaga tatatgaatg aagccaaaca
     3661 ggtatttaag caatatattg actcattcca gtttgcacct ttggcgatcc cggttatctc
     3721 caatgtctac gcagagccat accatcaaga cagattaaaa gatacattat ctgaacaaat
     3781 ggacaacaca gtgaaatgga cggacagcat tcgtttcctg atgggaagag gagaaatgga
     3841 gtttgcagag attgggcctg gaactgtatt aaccggtctc attcatcgga ttaaaaatga
     3901 agctgaacca ttgacatata taccgaaaaa gaaccccgcg atcagtgcgc atctaaagga
     3961 gcaacgcaat gttcaagccg ggattacggc agaatcttta ggaagtgctg aatttaaaca
     4021 agattatcat cttacatatg cttatcttgc aggaggaatg taccgcggca ttgcttcgaa
     4081 agaaatggta gtaaagctgt caagagcggg aatgatgggg ttctttggca caggaggtct
     4141 gagcctgaaa gaggttgaag atgcgatcca tgctatacaa ggtgaattag ggaaaggaca
     4201 agcctatggc atcaatctgg tccacaatat gaaacatact gaatcagaag aaaaaatgat
     4261 cgatctttta ttgaggaatc aagtgagcat tgtggaagct tcagcatttt taagtgtcac
     4321 tcctgcatta gtaaggtacc gcgcaaaagg agtgaaacga aatcaaaatg gtgacgttat
     4381 atgctcaaat cgtctcatag caaaaatatc acggccggaa gttgcagaat catttctgag
     4441 tcctgcacct gagaatatgc tgcaaaagct tttacgagaa aataaaatca ctatgaacga
     4501 agctgagttg ttgcggtgca ttccgatggc tgacgatatt tgtgtagaag ctgattcagg
     4561 cggtcataca gatggcggtg tggcatacag cctgatgccg gcgatgacat ctttaagaga
     4621 tgaaatgatg aaaaaatatc aatttcggaa aaaaataaga gttggggcag ctggagggat
     4681 tggaacacct gaggcagcga tggcggcttt tatgctaggg gctgacttta ttctaacagg
     4741 ctcaatcaat caatgtacgg ttgaggcggc aacaagtgat aaagtaaagg atttgcttca
     4801 gcagatgaat gtacaagata cagcctatgc gcctgcaggt gatatgtttg aatcgggcag
     4861 taaagtgcag gtgctaaaga aaggcgtgtt ctttcccgca cgggcaaaca agttatatga
     4921 actgtaccag cggtatgggt ctatacgtga gctggatgca aagatgctgg cccagcttga
     4981 ggagaaatac tttaaacgca gtatagaaga catatataaa gatattgcat tgcattatcc
     5041 cgcggcagac attgagaagg ctgaacaaaa cccgaagcat aaaatggctt tgattttccg
     5101 atggtacttc agatacagct caaaattggc aatcagcgga agcgaacatt cgaaggtcga
     5161 ttatcaaatt cactgcggtc ccgcgctggg agcctttaat caatgggtta aagggtcgca
     5221 atttgaaaat tggcgaaacc gccatgtgga tgaaatcggg aaaaaattaa tgacagaaac
     5281 ggcagtattg cttcatgaac ggatgcaatc gatgtatcag ccgtcgcatg caacagacaa
     5341 cataaaaata aaagtttgaa tattatgaaa atatacctat aaaaatcatc cctcgaagga
     5401 gagagcgcat tatggataaa cagagaatct ttgaagtact aatcaccaat atttgcgagg
     5461 tgcttcctga attagacgga cacagatttg agcctgaaga tcagttagtt gagctaggag
     5521 ctgactctgt agacagagct gaaattatca cgatggtgct agaggattta tcgttaaaaa
     5581 tccctcgcat tgagctatcc ggggtgaaaa acatcggtga attagctgag gtgctttatg
     5641 acaaagtgca atctgcctga ggtggtggtg accggtgtag gcgttacggc ctctatcggt
     5701 caagggaaag aggactttgc ttcctcgctg ctgtccggca gacatgcctt tgatgtcatg
     5761 aagcgttcag gcagacaaaa agacagccgg tttatcggag ccgaaattgc gtcattgtct
     5821 tatcctgacc gactctctaa aaaaatgttg cgaaaagcat cattctccag ccgcgctgca
     5881 ttggtaactc tcacagaggc ttgggaggag gctgaattgg acgatgcaga ttcctcacgt
     5941 atcggactgg ttgttggcgg gtcaaatttt cagcagagag aaaactttga agtttatgaa
     6001 aggtatcaag accgctccgg ttttatttct ccggcgtatg gcctgtcttt catggacagc
     6061 gatctttgcg ggatatgtac agatcagttt ggcatcacgg gattagcata tacggtggga
     6121 ggagcctcgg ccagcggcca gttagcagtc attcatgcga ttcagcaagt cctgtcaggc
     6181 gaagttgata cttgcattgc acttggtgct ttaatggatc tttcttatat ggaatgcgag
     6241 gcgctaagag ctttaggcgc tatggggacg gacaaatatg ctgatgaacc tgaaaaagcg
     6301 tgccgtccct tcgatcaaaa cagagacggg tttatctatg gagaatcgtg cggtgcattg
     6361 gtaatagaac gaaaggagac ggctttacga agaggtctca aaccttatgc agcattgtct
     6421 ggctggtcaa tcaaactgga cggaaaccgg aatcctgatc cttcattaga aggagagatt
     6481 catgtcatcc agaaggcact ggagcgtgcc aggcttttac cagaagatat tgattatatt
     6541 aatcctcatg gaacaggctc ttttattgga gatgaaatag aattaaaggc gctccgtgca
     6601 tgccggcttt cccatgctta tatcaatgca acaaaatcga taaccggaca cgggcttagt
     6661 gcggcgggca tcgtagagat tatttctgtt ttgctgcaaa tgaaaaaatc tgccctgcat
     6721 ccgagcagga atttggatca tccaatcgat gattcctttc attgggtaaa tgagaaatcg
     6781 atttcatacc gcatcaaaaa tgcgctgagt ttaagcatgg ggtttggcgg aatgaacacc
     6841 gcggtttgta tacaaaacat tgagaaatgt ggaggcgaat cataaatggt ttcagccgga
     6901 atagaagcga tgaatgtctt tggcggaacg gcataccttg atgtcatgga gctggccaaa
     6961 tacagacact tagatactgc gagatttgaa aacttattaa tgaaagaaaa agcggtagca
     7021 ctgccttatg aagatcccgt gaccttcgga gtcaatgcag ctaagccgat tattgatgct
     7081 ttatctgaag cagagaagga ccggattgaa ttgctgatca cttgctctga atccgggatc
     7141 gactttggga aatcgttaag tacatatatc catgaatatt taggtctcaa ccgcaactgc
     7201 cgtttgtttg aggttaaaca ggcgtgttat tcagggacag cgggatttca gatggcggtg
     7261 aattttatat tatcccaaac ttctccgggt gccaaagcac tggttatcgc cagtgatatt
     7321 tcacgttttt taatcgctga gggcggagac gctttaagcg aagattggtc ttatgcggaa
     7381 ccgagcgccg gagcgggagc ggtggccgtt ttagttggcg aaaatcccga ggtgtttcaa
     7441 atagatcccg gagcaaatgg ttattacggc tatgaagtga tggacacgtg ccgccccatt
     7501 cccgacagtg aagcgggaga ttctgatctg tctttaatgt catatttgga ttgctgcgaa
     7561 cagacctttc tggaatatca aaagcgtgta ccgggtgcca attatcagga cacgtttcaa
     7621 tatcttgctt accatacgcc ctttggcggg atggtgaaag gtgcgcaccg gacaatgatg
     7681 cgtaaggtgg cgaaggtgaa aacatccggg attgagacgg attttttaac tcgggtaaaa
     7741 ccaggtttaa actactgtca acgagttgga aatattatgg gggcagcctt gtttctggca
     7801 ttggccagca cgatagacca agggagattt gatacgccta aacgaattgg ctgtttttcc
     7861 tacggatccg gctgctgttc tgaattttac agcggaatta caactccgca aggccaggag
     7921 cgtcagcgaa catttggtat tgagaagcat ttggatcgcc ggtatcagct ctccatggaa
     7981 gagtatgagc tattgtttaa ggggagcggg atggtgcggt ttgggacgcg caatgtaaag
     8041 ctggactttg agatgatacc gggcatcatg cagtccactc aagagaagcc gcgcttgttt
     8101 ttagaagaaa tttctgagtt tcatcggaag tacaggtgga tctcgtgacc tatcaaacga
     8161 taaaggtccg ctttcaagcg tcggtttgct atattacctt tcaccgtcct gaagcgaata
     8221 atacgattaa tgatacgctg atagaagaat gcttgcaagt gttaaaccaa tgtgaaacat
     8281 caacggtgac ggttgtcgtt ttagaggggc ttcccgaggt gttttgtttc ggagcggatt
     8341 ttcaagaaat ctatcaggaa atgaaaaggg gcagaaaaca ggcaagctcc caagagcctc
     8401 tctatgattt gtggatgaaa ttgcagaccg gcccttatgt cacgatttcg catgtcaggg
     8461 gaaaagtgaa tgccggcggt cttggatttg tatctgccac agatattgcc attgctgatc
     8521 agacggcgtc attcagtctc tctgagctgc tattcggcct gtaccctgct tgtgttttac
     8581 cgtttctgat ccgccgtatc ggccggcaga aagcgcatta tatgacgctt atgacaaagc
     8641 cgatttccgt tcaggaagcc agtgaatggg ggttaataga tgcttttgat gctgaaagtg
     8701 acgtgctgct gagaaagcat ttattgcgtt tgcggaggct gaataaaaaa ggaatcgcac
     8761 attataaaca gtttatgagc tcacttgatc atcaagtcag tcgtgcgaaa gccaccgctt
     8821 taactgcaaa tcaaaacatg ttttctgatc ctcaaaacca aatgggaatc atcaggtatg
     8881 ttgaaacagg acaattccca tgggaggatc agtaaccgtt tcaatcagaa ccgttaggag
     8941 gacatcatga cgcattctgt tgtagagctt atcgaaattg aatccgccat tattcaggta
     9001 aagatgcaag atcgcactca taaaaacgct ttttcacaag aacttacaga tggtttaatt
     9061 caagcgttta aatacatacg gcagaacccc aaatacaaag cggtcatttt gacaggatat
     9121 gataattatt ttgcttcagg aggaacgcaa gaaggactgc tacgaattca acagggattg
     9181 accaagttca ctgatgacaa tctttattct ctggcgctgg attgcgagat tccagttatt
     9241 gcggcaatgc agggccatgg aattggaggc ggctttgtca tggggctctt tgctgacata
     9301 gtcattctga gcagggaaag cgtgtatacg gctaatttta tgaaatacgg atttacgcct
     9361 ggaatgggcg ctacctttat cgttcctaaa aaactgggtt tcagcctgtc ccaggaaata
     9421 ttattgaatg caggcagcta ccgcggagct gatcttgaaa aaagaggggt tccctttaag
     9481 gtgctgcccc gtgcagaagt gttagattat gcagtggagc tggcgcaaga actggcggaa
     9541 aagcctagaa actcactggt tacactgaaa gatcatttgg ttgcttcgct tcgcgatcag
     9601 ctgccgcgcg tcattgaaca ggaattggtg atgcatgaga aaacatttca tcatgaagaa
     9661 gtcaaaagta gaatcaaagg tttatatggt aattaactga aaacatataa aaattttgca
     9721 ggtgaaatgg aggcagcgtg atgagaaata atgataatat ccgcatatta gctaatcctt
     9781 ctgtcagtca tggtgagcct ttacatatat ctgaaaagca gccggcaaca atacctgaag
     9841 ttttatacag aacggcggcg gagcttgggg atacaaaggg aatcatttat ttgcagccgg
     9901 atggaactga ggtttaccaa tcatacagac gattatggga tgatggactg cgtattgcaa
     9961 aggggcttcg ccaatcaggc ctgaaagcaa aacaaagcgt gattttgcag cttggtgaca
    10021 attcacagct tctccctgcg ttctgggggt gtgtgttaac agggggtgtt ccggctccat
    10081 tagccgttcc gccaacgtat gctgaatcga gcagcggcac tcaaaagctg aaagacgcat
    10141 ggacgcttct tgacaagcca gcggtgatta cggaccgggg gatgcaccag gaaatgctcg
    10201 attgggcaaa agaacaaggg cttgaagggt tcagggcaat tgttgtagag gatctgctca
    10261 gcgctgaagc ggacacagat tggcatcaat ccagtcccga agacttagcg cttttattgc
    10321 tgacttcagg cagtacggga acgcccaaag cagttatgct taatcatcgt aacattatga
    10381 gcatggtgaa agggattatt caaatgcaag gcttcaccag agaggatatt acgtttaact
    10441 ggatgccgtt tgaccatgtc ggagggatcg gaatgttgca tttgcgggat gtttatcttg
    10501 gctgtcagga aattaacgtc tcaagcgaaa caatcttaat ggagccgttg aaatggctgg
    10561 attggattga tcattaccga gcttctgtta cgtgggcgcc gaattttgcg tttggcctgg
    10621 ttactgattt tgcagaagaa ataaaagata ggaaatggga tctgtcttca atgcgataca
    10681 tgctcaatgg cggtgaagca atggtagcca aggtagggcg cagaatactt gagcttttag
    10741 aaccacatgg actgcctgct gacgccatcc gacctgcatg gggaatgtcc gaaacttcat
    10801 cgggcgttat tttttctcat gaatttaccc gggctggaac aagtgatgat gatcattttg
    10861 ttgaaatagg ctctccaatc cccggcttct ctatgagaat tgtgaatgac cataatgaat
    10921 tggttgaaga gggcgagatc ggccgttttc aagtctcggg tctttctgtt actagcggtt
    10981 attaccagcg gcctgatttg aatgagagtg tgtttacaga ggacggctgg tttgaaaccg
    11041 gagatcttgg ctttttgcga aacgggcgct taaccataac aggtcgtacg aaagatgcaa
    11101 ttatcattaa cggcattaat tattacagtc atgcaattga gtctgcagtt gaagaattat
    11161 ctgaaattga aacttcttat actgctgctt gcgctgtccg tctgggccag aattcaacag
    11221 atcagctggc tatcttcttt gttacttccg caaaattaaa tgatgagcag atgtctcagc
    11281 ttcttagaaa catacaatcc catgtctcac aggtgatcgg agtcaccccg gaatatttgc
    11341 tgcctgtaca aaaagaagag attccaaaaa cggctattgg aaagatccag cgcacccagc
    11401 taaaaacttc atttgaaaat ggagagttcg accacttgct acataaaccc aatcggatga
    11461 acgatgcggt ccaggatgag gagatgcagc aagcagacca tgtgaaaaga gtaagggaag
    11521 aaatacagga gcatctgctc acctgtttga ctgaggagct gcatgtttcc cgcgattggg
    11581 tggagccaaa tgcaaatatc caaagtcttg gtgtgaattc tattaagatg atgaagctca
    11641 ttcgatcgat cgagaaaaac taccatatca aactaacagc cagagagata catcaatatc
    11701 ctacaattga acgcttagcc agctatctat cagaacatga agacctcagc agctcgtctg
    11761 ctgacaaaaa gggcacggac acatataaaa ccgaaccgga aaggagtcag gcaacttttc
    11821 agcctctctc tgaggttcaa aaaggattat ggacattgca aaaaatgtca cccgaaaaaa
    11881 gtgcatatca cgtacctctc tgttttaaat tttcgtcagg gcttcacctt gaagcattac
    11941 agcaggcttt cggccttgta ttgaatcagc acccaatctt aaagcacgtc atccaagaga
    12001 aagacggagt gccatttctt aaaaatgagc cagcactttc aattgaaatc aagacagaaa
    12061 acatctcaag tatgaaagag tctgatattc ctgcttttct tagaaagaaa gtaaaggaac
    12121 cgtatgtaaa ggaaaacagc ccgttagtgc gtgtcatgag cttttccaga tctgaacaag
    12181 agcatttttt attagttgtc attcaccatt tgatttttga cggagtttcg tctgtcacat
    12241 ttatacacag tctgtttgat acctatcagc ttcttttaaa aggacagcag ccggaaatag
    12301 ctgtttctcc tgccatttat catgattttg cggcatggga gaaaaacatg cttgccggca
    12361 aagacggtgt gaagcatcgt acatattggc agaaacagct atcgggaact ttgccgaatc
    12421 ttcagcttcc taaggtcagc gcaagttcag tgtctgagtt tagagaggat acatacacca
    12481 ggcggctgtc cagcggcttc atgaatcagg tcagaatgtt tgcgaaagag cattctgtaa
    12541 atgtcacgac ggtattctta agctgctata tgatgctgct tggccgttac accggccaaa
    12601 aggaacagat cgtcggcatg ccggccatgg tgaggccgga agaaagattt gatgatgcca
    12661 ttggacattt tctcaatatg ctcccgattc ggagtgagct gaacccggca gacacttttt
    12721 ctagctttat ttcaaaattg caattaacga tattggatgg gcttgatcat gcagcatatc
    12781 cttttccaaa aatggtgagg gatctgaata ttcctcgcag tcaagcaggt tcaccggtat
    12841 ttcaaaccgc ttttttctat cagaattttc ttcaatccgg aagctatcaa agcttgctga
    12901 gccgctatgc tgacttcttt tctgtcgatt acgttgagta tattcaccaa gagggcgaat
    12961 acgaattagt atttgaactg tgggaaacag aagaaaaaat ggagctgaac atcaagtaca
    13021 atactgggct gtttgatgcg gcttctatat ccgccatgtt cgaccatttt gtttatgtaa
    13081 cagagcaggc gatgttgaat ccttctcagc ctttaaaaga gtattcttta ttacctgagg
    13141 cagagaagca gatgattctc aaaacatgga acgccacagg aaaaacgtat ccatatataa
    13201 cttttcatga gttgtttgag cagcaggcga aaaagacgcc tgatagagcg gctgtcagct
    13261 atgaaggtca aacattgacg tatcgggagc ttgatgagaa aagcacacag ctggccattt
    13321 atttgcaggc gcatggagtg ggtcctgacc gtctggcggg gatctatgtg gatcgatcgc
    13381 tggacatgct agtgggttta ttagcgatcc tcaaggctgg gggagcgtat gtgccgctag
    13441 acccgtccta tccggctgaa cgattagaat acatgcttga ggacagtgaa gttttcatta
    13501 cactgacgac atcggaatta gtaaatacgt tgagttggaa cggtgtcaca acagcccttt
    13561 tagatcaaga ttgggatgaa attgctcaaa cagcctctga tcgaaaagtg cttacacgca
    13621 ctgtcacgcc agagaacttg gcatatgtca tttatacatc cggcagcaca ggaaagccaa
    13681 aaggtgtcat gataccacat aaagctttga caaactttct cgtttcgatg ggggaaacac
    13741 caggtcttac ggcagaggat aaaatgcttg ctgtcacaac ctactgtttt gatattgcag
    13801 ctctggaatt atttttgcct ttaataaagg gcgcacactg ctatatttgt caaacggagc
    13861 atacaaaaga cgttgaaaaa ctgaaacggg acatccgcgc gatcaaaccg acagtgatgc
    13921 aggcaacccc cgctacgtgg aagatgctct tttattcagg ctgggaaaat gaagagagcg
    13981 tgaaaatttt atgcggtggc gaagcattgc ctgagacatt aaaacgatat ttcctgcata
    14041 cgggcagcga agcctggaat atgttcgggc caaccgaaac aactatctgg tcagcggttc
    14101 agcgcattaa cgttgaatgc tctcatgcca cgataggaag gccaatcgcc aatacacaaa
    14161 tctatattac ggattctcag ctcgcgccag tgccggcagg tgttccgggt gagctgtgca
    14221 ttgcaggaga cggtgtggcg aagggctact acaaaaagga agaattaacg gattcgagat
    14281 tcattgacaa cccttttgag cctgggtcta agctttatag aacgggagac atggcccgct
    14341 ggcttacggg agggcgaatt gaatatatag gccgcatcga taatcaagta aaaatccgcg
    14401 gattccgtat tgaacttggt gatattgaaa gcaggcttag tgagcatccc ggcattctgg
    14461 aatgcgttgt ggtcgcagat atggataacc tagctgccta ttatacagct aaacatgcaa
    14521 atgcttctct cacagcgaga gagctgcgtc attttgtgaa aaatgctttg cctgcctata
    14581 tggtaccttc ttattttatt cagcttgatc atatgccgtt aactccgaat ggaaagatag
    14641 atagaaacag ccttaagaat atcgatttat caggggagca gctaaagcaa aggcagacct
    14701 ctcctaagaa cattcaggat actgttttta ccatttggca ggaagtgctg aaaacgagtg
    14761 acattgaatg ggatgacgga tttttcgatg tgggcgggga ttcgcttctc gcggtcactg
    14821 tggctgatcg catcaaacat gaactatcct gtgagttttc tgtcacagac ctgtttgagt
    14881 attcaacgat taaaaatatc agccagtaca tcactgaaca gcgaatgggc aatgcaagtg
    14941 accatatgcc gacagacccg ccagctcata tagaagatca gtctaccgag atgagtgatc
    15001 tcccggacta ttatgacgat agtgtggcga ttattggcat atcgtgtgaa tttccagggg
    15061 caaaaaatca tgatgaattt tgggagaacc tcagagacgg caaggaaagt attgcgtttt
    15121 tcaataaaga agagcttcag cgctttggca tttcaaagga gatagcggag aatgccgact
    15181 atgtccctgc taaagcttca attgagggga aagacagatt tgatccaagc ttctttcaaa
    15241 tctctcctaa agacgctgaa tttatggacc ctcagcttcg gatgctgctg actcattcat
    15301 ggaaagcaat agaagatgcc ggt
//
