LOCUS gnlProkkaEGKHHCPB_9 38501 bp DNA linear UNK 01-JAN-1980 DEFINITION gnl|Prokka|EGKHHCPB_9. ACCESSION gnlProkkaEGKHHCPB_9 VERSION gnlProkkaEGKHHCPB_9 KEYWORDS . SOURCE ORGANISM . COMMENT ##antiSMASH-Data-START## Version :: 7.1.0 Run date :: 2025-04-28 23:25:30 Original ID :: gnl|Prokka|EGKHHCPB_9 NOTE: This is a single region extracted from a larger record! Orig. start :: 0 Orig. end :: 38501 ##antiSMASH-Data-END## FEATURES Location/Qualifiers protocluster 1..38501 /aStool="rule-based-clusters" /category="NRPS" /contig_edge="True" /core_location="[1:18501]" /cutoff="20000" /detection_rule="cds(Condensation and (AMP-binding or A-OX))" /neighbourhood="20000" /product="NRPS" /protocluster_number="1" /tool="antismash" proto_core 2..18501 /aStool="rule-based-clusters" /tool="antismash" /cutoff="20000" /detection_rule="cds(Condensation and (AMP-binding or A-OX))" /neighbourhood="20000" /product="NRPS" /protocluster_number="1" cand_cluster 1..38501 /SMILES="NC(C(C)C)C(=O)N1C(CCC1)C(=O)NC(CCC(=O)O)C(=O)NC(Cc 1ccc(O)cc1)C(=O)NC(C(C)CC)C(=O)O" /candidate_cluster_number="1" /contig_edge="True" /detection_rules="cds(Condensation and (AMP-binding or A-OX))" /detection_rules="(HMGL-like and AMP-binding)" /kind="chemical_hybrid" /product="NRPS" /product="betalactone" /protoclusters="1" /protoclusters="2" /tool="antismash" region 1..38501 /candidate_cluster_numbers="1" /contig_edge="True" /product="NRPS" /product="betalactone" /region_number="1" /rules="cds(Condensation and (AMP-binding or A-OX))" /rules="(HMGL-like and AMP-binding)" /tool="antismash" CDS 2..3814 /NRPS_PKS="Domain: AMP-binding (225-618). E-value: 8.9e-116. Score: 378.7. Matches aSDomain: nrpspksdomains_ctg9_1_AMP-binding.1" /NRPS_PKS="Domain: PCP (723-791). E-value: 3.3e-24. Score: 76.8. Matches aSDomain: nrpspksdomains_ctg9_1_PCP.1" /NRPS_PKS="Domain: Epimerization (801-1103). E-value: 3.5e-168. Score: 552.6. Matches aSDomain: nrpspksdomains_ctg9_1_Epimerization.1" /NRPS_PKS="Domain: TIGR01720 (1109-1263). E-value: 1e-52. Score: 170.0. Matches aSDomain: nrpspksdomains_ctg9_1_TIGR01720.1" /gene_functions="biosynthetic (rule-based-clusters) NRPS: Condensation" /gene_functions="biosynthetic (rule-based-clusters) NRPS: AMP-binding" /gene_functions="biosynthetic-additional (rule-based-clusters) PP-binding" /gene_functions="biosynthetic-additional (smcogs) SMCOG1002:AMP-dependent synthetase and ligase (Score: 338.3; E-value: 1e-102)" /gene_kind="biosynthetic" /locus_tag="ctg9_1" /sec_met_domain="AMP-binding (E-value: 8.7e-121, bitscore: 395.5, seeds: 400, tool: rule-based-clusters)" /sec_met_domain="PP-binding (E-value: 9.1e-14, bitscore: 44.0, seeds: 164, tool: rule-based-clusters)" /sec_met_domain="Condensation (E-value: 2.4e-78, bitscore: 255.4, seeds: 42, tool: rule-based-clusters)" /transl_table=11 /translation="MNGSTLYMVLLAAYTAFLSRLSGQEDIIVGSPIAGRPHKDLEPIL GMFVNTLALRTRPEGGKPFVQYLQEVRETALEAFEHQDYPFEELVDKLELTRDMSRNPL FDVMFVLQNMDQESLELNELCLKPAAHNGHQTSKFDLTLYTQEQPRGLLTFQMEFSTDL YKKKTIEKWLQYFINMLLSIIKDNKAALGTINILNEDETHYLIHELNRTKIDYPRNETI SRLFEMQAEQTPNAVAIVSDTQVFTYEDLNSWANQIASVLQIKGVGPDSVVALLTGRTP ELIAGMLGILKAGGAYLPIASDLPVERIAYMLSDSGAALLLQSEKTEKQLLDIECEQII IEDIQKQGKTKNVDSSAGPHSLAYIIYTSGSTGKPKGVMIEQRSVIRLVKNSNYITFTP EDRLLMTSSIGFDVGSFEIFGPLLNGAALHLSDQQTFLDSHQLKRYIEHQGITTIWLTS SLFNHLTEQNEQTFSQLKHLIIGGEALSPSHVNRIRNVCPEVSIWNGYGPTENTTFSTC LHIQKTYELSIPIGRPVGNSTAYILNQWGVLQPVGAVGELCVGGDGVARGYLGRPDLTK EKFVPHPFAPGDRLYRTGDLARWLPDGTIEYVGRIDDQVKVRGYRVELGEIETAFRQID GVKEAAVLARTAQTGSKELFGYISVKAGTNAEQVRSLLACSLPNYMIPAYIIEMENLPL TSNGKLNRKALPEPDFASKQTYIPPRNELEEQLALIWQEVLGIQRIGIEDSFFELGGDS IKALQVSARLGRHGLSLQVSDLFRRPKIKDLSPFIRKTERVIEQGPVQGDVPWTPIQKW FLSQDIEERHHFNQSVMLFHTDRLSEDALRASLKKLAEHHDALRMVYRNDDRRWIQINQ GIHESQLYSLRTFDLSQSESGWETQIKQEVADLQQSINLQEGPLLHAALFKTLTGDYLF LAIHHLVVDGVSWRILLEDLSAGYQQAAAGQTIQLPPKTDSYQEYARRIQEYAQSSKLI REEAYWRTVEEQQDAELPYEIPHQVNIDFSKRDSLNFSLTEADTAVLLQNVNHAYGTDT QDILLTAASLAICEWTGGSKLRIAMEGHGREHILPELDISRTVGWFTSMYPALISFENH RDELGTALKTVKDTLGRIPNKGVGYGMLKYLTHPENKSITFSKTPEISFNYLGQFNDIE RQDTFRPSSLGSGKDITHTWKREQIIEMSAMAADKKLHFNLSYPPARFHRNTMEQLINR IEHFLLDIMKHCAGQQKTEKTLSDFSSQSLTAEDLDSISSLVEEL" CDS_motif 77..166 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_1_0001" /evalue="1.40E-15" /label="C5_LCL_267-296" /locus_tag="ctg9_1" /protein_end="55" /protein_start="25" /score="49.6" /tool="antismash" /translation="DIIVGSPIAGRPHKDLEPILGMFVNTLALR" CDS_motif 215..334 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_1_0002" /evalue="9.20E-23" /label="C67_LCL_14fromHMM" /locus_tag="ctg9_1" /protein_end="111" /protein_start="71" /score="72.7" /tool="antismash" /translation="RETALEAFEHQDYPFEELVDKLELTRDMSRNPLFDVMFVL" aSDomain 677..1855 /aSDomain="AMP-binding" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg9_1_AMP-binding.1" /evalue="8.90E-116" /label="ctg9_1_AMP-binding.1" /locus_tag="ctg9_1" /protein_end="618" /protein_start="225" /score="378.7" /specificity="substrate consensus: Val" /tool="antismash" /translation="FEMQAEQTPNAVAIVSDTQVFTYEDLNSWANQIASVLQIKGVGPD SVVALLTGRTPELIAGMLGILKAGGAYLPIASDLPVERIAYMLSDSGAALLLQSEKTEK QLLDIECEQIIIEDIQKQGKTKNVDSSAGPHSLAYIIYTSGSTGKPKGVMIEQRSVIRL VKNSNYITFTPEDRLLMTSSIGFDVGSFEIFGPLLNGAALHLSDQQTFLDSHQLKRYIE HQGITTIWLTSSLFNHLTEQNEQTFSQLKHLIIGGEALSPSHVNRIRNVCPEVSIWNGY GPTENTTFSTCLHIQKTYELSIPIGRPVGNSTAYILNQWGVLQPVGAVGELCVGGDGVA RGYLGRPDLTKEKFVPHPFAPGDRLYRTGDLARWLPDGTIEYVGRIDDQVKVR" aSModule 677..3790 /complete /domains="nrpspksdomains_ctg9_1_AMP-binding.1" /domains="nrpspksdomains_ctg9_1_PCP.1" /domains="nrpspksdomains_ctg9_1_Epimerization.1" /domains="nrpspksdomains_ctg9_1_TIGR01720.1" /locus_tags="ctg9_1" /monomer_pairings="Val -> D-Val" /starter_module /tool="antismash" /type="nrps" CDS_motif 863..901 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_1_0003" /evalue="1.70E-04" /label="NRPS-A_a2" /locus_tag="ctg9_1" /protein_end="300" /protein_start="287" /score="14.9" /tool="antismash" /translation="LGILKAGGAYLPI" CDS_motif 1088..1144 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_1_0004" /evalue="1.10E-10" /label="NRPS-A_a3" /locus_tag="ctg9_1" /protein_end="381" /protein_start="362" /score="33.3" /tool="antismash" /translation="AYIIYTSGSTGKPKGVMIE" CDS_motif 1649..1738 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_1_0005" /evalue="4.50E-18" /label="NRPS-A_a6" /locus_tag="ctg9_1" /protein_end="579" /protein_start="549" /score="57.3" /tool="antismash" /translation="PVGAVGELCVGGDGVARGYLGRPDLTKEKF" CDS_motif 1820..1885 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_1_0006" /evalue="1.90E-12" /label="NRPS-A_a8" /locus_tag="ctg9_1" /protein_end="628" /protein_start="606" /score="39.0" /tool="antismash" /translation="YVGRIDDQVKVRGYRVELGEIE" aSDomain 2171..2374 /aSDomain="PCP" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg9_1_PCP.1" /evalue="3.30E-24" /label="ctg9_1_PCP.1" /locus_tag="ctg9_1" /protein_end="791" /protein_start="723" /score="76.8" /tool="antismash" /translation="EEQLALIWQEVLGIQRIGIEDSFFELGGDSIKALQVSARLGRHGL SLQVSDLFRRPKIKDLSPFIRKT" aSDomain 2405..3310 /aSDomain="Epimerization" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg9_1_Epimerization.1" /evalue="3.50E-168" /label="ctg9_1_Epimerization.1" /locus_tag="ctg9_1" /protein_end="1103" /protein_start="801" /score="552.6" /tool="antismash" /translation="GDVPWTPIQKWFLSQDIEERHHFNQSVMLFHTDRLSEDALRASLK KLAEHHDALRMVYRNDDRRWIQINQGIHESQLYSLRTFDLSQSESGWETQIKQEVADLQ QSINLQEGPLLHAALFKTLTGDYLFLAIHHLVVDGVSWRILLEDLSAGYQQAAAGQTIQ LPPKTDSYQEYARRIQEYAQSSKLIREEAYWRTVEEQQDAELPYEIPHQVNIDFSKRDS LNFSLTEADTAVLLQNVNHAYGTDTQDILLTAASLAICEWTGGSKLRIAMEGHGREHIL PELDISRTVGWFTSMYPALIS" CDS_motif 2498..2581 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_1_0007" /evalue="2.60E-05" /label="C2_LCL_024-062" /locus_tag="ctg9_1" /protein_end="860" /protein_start="832" /score="16.6" /tool="antismash" /translation="TDRLSEDALRASLKKLAEHHDALRMVYR" CDS_motif 2786..2851 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_1_0008" /evalue="1.30E-12" /label="NRPS-E2" /locus_tag="ctg9_1" /protein_end="950" /protein_start="928" /score="39.7" /tool="antismash" /translation="LFLAIHHLVVDGVSWRILLEDL" CDS_motif 3257..3304 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_1_0009" /evalue="6.00E-09" /label="NRPS-E5" /locus_tag="ctg9_1" /protein_end="1101" /protein_start="1085" /score="27.8" /tool="antismash" /translation="DISRTVGWFTSMYPAL" aSDomain 3329..3790 /aSDomain="TIGR01720" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg9_1_TIGR01720.1" /evalue="1.00E-52" /label="ctg9_1_TIGR01720.1" /locus_tag="ctg9_1" /protein_end="1263" /protein_start="1109" /score="170.0" /tool="antismash" /translation="ELGTALKTVKDTLGRIPNKGVGYGMLKYLTHPENKSITFSKTPEI SFNYLGQFNDIERQDTFRPSSLGSGKDITHTWKREQIIEMSAMAADKKLHFNLSYPPAR FHRNTMEQLINRIEHFLLDIMKHCAGQQKTEKTLSDFSSQSLTAEDLDSI" CDS_motif 3353..3415 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_1_0010" /evalue="1.20E-09" /label="NRPS-E6" /locus_tag="ctg9_1" /protein_end="1138" /protein_start="1117" /score="30.3" /tool="antismash" /translation="VKDTLGRIPNKGVGYGMLKYL" CDS_motif 3455..3484 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_1_0011" /evalue="4.10E-03" /label="NRPS-E7" /locus_tag="ctg9_1" /protein_end="1161" /protein_start="1151" /score="9.7" /tool="antismash" /translation="PEISFNYLGQ" aSDomain 3840..3929 /aSDomain="NRPS-COM_Nterm" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg9_2_NRPS-COM_Nterm.1" /evalue="3.40E-18" /label="ctg9_2_NRPS-COM_Nterm.1" /locus_tag="ctg9_2" /protein_end="30" /protein_start="0" /score="56.5" /tool="antismash" /translation="MTKANSIQDIYPLSYMQEGMLFHSLLQKDS" CDS 3840..14654 /NRPS_PKS="Domain: NRPS-COM_Nterm (0-30). E-value: 3.4e-18. Score: 56.5. Matches aSDomain: nrpspksdomains_ctg9_2_NRPS-COM_Nterm.1" /NRPS_PKS="Domain: Condensation_DCL (7-304). E-value: 3e-117. Score: 382.8. Matches aSDomain: nrpspksdomains_ctg9_2_Condensation_DCL.1" /NRPS_PKS="Domain: AMP-binding (468-865). E-value: 1.1e-104. Score: 342.1. Matches aSDomain: nrpspksdomains_ctg9_2_AMP-binding.1" /NRPS_PKS="Domain: PCP (971-1040). E-value: 2e-23. Score: 74.3. Matches aSDomain: nrpspksdomains_ctg9_2_PCP.1" /NRPS_PKS="Domain: Condensation_LCL (1054-1333). E-value: 2.4e-101. Score: 330.5. Matches aSDomain: nrpspksdomains_ctg9_2_Condensation_LCL.1" /NRPS_PKS="Domain: AMP-binding (1499-1900). E-value: 9.9e-113. Score: 368.6. Matches aSDomain: nrpspksdomains_ctg9_2_AMP-binding.2" /NRPS_PKS="Domain: PCP (2002-2071). E-value: 2.1e-25. Score: 80.6. Matches aSDomain: nrpspksdomains_ctg9_2_PCP.2" /NRPS_PKS="Domain: Condensation_LCL (2085-2373). E-value: 5.4e-110. Score: 358.9. Matches aSDomain: nrpspksdomains_ctg9_2_Condensation_LCL.2" /NRPS_PKS="Domain: AMP-binding (2538-2932). E-value: 1e-112. Score: 368.6. Matches aSDomain: nrpspksdomains_ctg9_2_AMP-binding.3" /NRPS_PKS="Domain: PCP (3039-3106). E-value: 5.9e-27. Score: 85.6. Matches aSDomain: nrpspksdomains_ctg9_2_PCP.3" /NRPS_PKS="Domain: Epimerization (3116-3429). E-value: 3.4e-152. Score: 499.8. Matches aSDomain: nrpspksdomains_ctg9_2_Epimerization.1" /NRPS_PKS="Domain: TIGR01720 (3441-3597). E-value: 2.5e-45. Score: 145.9. Matches aSDomain: nrpspksdomains_ctg9_2_TIGR01720.1" /gene_functions="biosynthetic (rule-based-clusters) NRPS: Condensation" /gene_functions="biosynthetic (rule-based-clusters) NRPS: AMP-binding" /gene_functions="biosynthetic-additional (rule-based-clusters) PP-binding" /gene_functions="biosynthetic-additional (smcogs) SMCOG1002:AMP-dependent synthetase and ligase (Score: 368.6; E-value: 6.6e-112)" /gene_kind="biosynthetic" /locus_tag="ctg9_2" /sec_met_domain="Condensation (E-value: 6e-99, bitscore: 323.0, seeds: 42, tool: rule-based-clusters)" /sec_met_domain="AMP-binding (E-value: 8.9e-123, bitscore: 402.0, seeds: 400, tool: rule-based-clusters)" /sec_met_domain="PP-binding (E-value: 3.6e-16, bitscore: 51.7, seeds: 164, tool: rule-based-clusters)" /transl_table=11 /translation="MTKANSIQDIYPLSYMQEGMLFHSLLQKDSQAYVEQASFTIEGKV NPQFFQNSINALVERHDIFRTIFISQNVSSPQQVVLRERNVIVLEENITHLNEAEQSQF IEQWKEKDRDQGFHLQKDVLMRIALIQTGESQYSCIWTFHHIMMDGWCLSIVLKEFLHI YASYVNASPITLEPVQPYGKYIKWLMEQDKEQAVSYWDHYLSGHEQQTVLPKQKKTKGK SRQEHVTFSFSKEESSRLSELAAREEVTLSTIFHTIWGILLQKYNNNDDAVFGSVISGR PAEIEGIEHMVGLFINTMPVRVQGAKTPFLQLIKDMQKDRLAAEAYSYHPLYEIQSRSA VKQGLIDHILVFENYPVQQEIQMLNKQEHASDLFQIHNFTVADETNYSFYLMVAPGEEI HIKMNYDAEQHDRSFVLSVKEHLLNAVSQILNNPNLPPEEIDITTDTEKRQLIGEITDQ TPVYETIHAMFEKQAEKTPDAHAVIDQACSLTYRELNKAANRLARHLRMKGVVRQEPVA IMMERSAAFITGVLGILKAGGAIVPVDPHYPADRIRYILHDCGCSHVVSQAHLPSSLED NYIITHPEDIESKVDGSNIKSVNNADDLLYMIYTSGTTGKPKGVQFEHRNMANLLKFEY THSGIDFEADVLQFATPSFDVCYQEIFSALLKGGTLHIVPEAIKRDVPQLFAFINKHQT NIVFLPTAFIKMIFSERELANSFPDGVKHLIAAGEQLMISDLFQDVLRKRGIHLHNHYG PSETHVVSTYTIHPGDPIPELPPIGKPIGCTDLYILNHQKQLQPCGVPGELYISGASVA RGYVNHDKLTSDKFSSDPFKPDVIMYRTGDLARRLEDGNIEYIGRADNQVKIRGYRIEP QEIEVTLMNHPDISEAAILIWQDQNGEHELCAYYCSVQKLNAIDLRSYMASELPEYMIP SKWIWVDSIPLTPNGKVDRAALPEPDASISGNPYTAPRNLLEAKLSQLFEDVLKNGHIG IQDNFFDNGGHSLKATVLMSRIAKEFHVQVSLKDIFAHPTVEGLALIIREAEQNLYAAI EPAEERDTYPVSSAQKRIYVLQQLDEGVAYNMPAVLELEGALDVAKLSAVCKELISRHE PLRTSFVSGADDEPVQRIHTEVPFTLSKETTIEGFVRPFCLSQAPLFRAGLIEVSNEKH VLLVDMHHIISDGVSVQLLIREFTDLYANRQLKPLRIQYKDYAVWQQKFKKGDSYQKQE TYWQQQFSGDLPILELPTDKRRPAERQFIGGKVTFQLDKEITARIKRLAHKNRSTLYMT LLALYSAFLSRLSGQDDIVIGSPIAGRPHADLEAVLGMFVNTLALRTRPAGNKTFEEFL KEVRQTALEAYEHQDYPFEELVDKLGVQREMSRNPLFDTTLVLQNMEQQKLKMNDVQLQ WNDLEHPISKFDISLYVTEHDSELFCQFEYSTALFEKETIQRWASLFTTLVEHTAASPE TELDNIPILTKEEERDFIESCHLFEETGYSMNQTLHYALEQQAEKTPDQAAVIFEDGVM TYKELNEQANRIAWELIGRGVKPETTVAIIGKRSPEMLLGIYGILKAGGAYLPIDPDYP EERISFLLEDSGTNILLLQSAGLHVPAFTGEIVYLNQTNSGLAHRLSNPNVDVLPQSLA YVIYTSGSTGMPKGVEIEHRSAVNFLNSLQSRYQLKHSDMIMHKTSYSFDASIWELFWW PYAGASVYLLPQGGEKEPEVIAKAIEEQKITAMHFVPSMLHAFLEHIKYRSVPIKTNRL KRVFSGGEQLGTHLVSRFYELLPNVSITNSYGPTEATVEAAFFDCPPQEKLERIPIGKP VHHVRLYILNQNQRMLPVGCIGELYIAGAGVARGYLNRPALTEERFLEDPFYPGERMYK TGDVARWLPDGNIEFLGRTDDQVKIRGYRIEPGEIEAALRSIEGVREAAVTVRTDSGEP ELCAYIEGLQRNEVRAQLERLLPGYMVPAYMIEMKQWPVTPSGKLDRNALPAPGGAADA ETYTAPRNVTEMKLSQLWEDVLKNGPVGIHDNFFDRGGHSLKATALVSRITKEFDVQVP LKDVFAHPTVEGLAAVIREGTDSPYEAIKPAEKQETYPVSSAQKRIYVLQQLEDGGTGY NMPAVLELEGKLNPERMDRAFKELIKRHESLRTSFEQDAGGDPVQRIHDEVPFTLQTTV LGERTEQEAAAAFIKPFDLSQAPLFRAQIVKVSDERHLLLVDMHHIISDGVSVNILIRE FGELYNNRNLPALRIQYKDYAVWQEGFKTRDAYKTQGAYWLKQLEGELPVLDLPADHVR PPVRSFAGDKVSFTLDQEVASDLHKLARENGSTLYMVLLAAYTAFLSRLSGQEDIIVGS PIAGRPHKDLEPILGMFVNTLALRTRPEGGKPFVQYLQEVRETALEAFEHQDYPFEELV DKLELTRDMSRNPVFDAMLVVQNNDYERLHLHDLQMKPAQVSHLVSKFDLTLQASEGDG NIHFLFEYSTALFEKTTIERWASHLTNVLSIIGKNPEVTLNHIDILTQEERHQLLNEFN TRQANQYGVQTISQLFEQQAARTPKATALVSGDKTLTYQELDEWSNGIARALRNRGVKP DTPVGIMMHRSFSMIASILGVWKAGGCYVPIDPEYPKERKRYILSDSGTKLLMTINEAD LGVLADFEGEILTIESVEEDDKSPLPQMSSAHHLAYIIYTSGTTGRPKGVMVEHKGIAN TLQWRRNAYAFNETDTILQLFSFSFDGFITSMFTPLLSGAKAVLLHEEEAKDILAIKHQ LSRQRITHMIIVPVLYRALLDVVQPEDVKTLRVVTLAGEAADRELIARSLAICPHTELA NEYGPTENSVATTVMRHMEKQAYVSIGQPIDGTQVLILNSNHQLQPIGVAGELCIAGTG LARGYVNLPELTERAFTQNPFKPEARMYRTGDAARWMADGTLEYLGRIDDQVKIRGYRV ETKEIESVIRCIKGVKDAAVVAHVTASGQTELSAYVVTKPGLSTNAVRSELQNKLPVFM HPAFIEKLDSLPLSPNGKLDRGALPKPVYNHEGERPFLPPSSKMEQILADIWKEVLGAE KIGTADSFFELGGDSIKALQVSARLHRIGKQMAVKDLFSHPTIQELAAYIRDSDTSSSQ AAVEGDVQWSPVQKWFLSQDIKEKHHFNQSVMLHRSTSVQEDALRKTLKAITCHHDALR MVFTQNEQGKWDQYNRPLSHSDDALYGLQMIDLSAPDGTDGNRAYEPIIKRHVLDIQQK MDLKNGPLLQAGLFHTIDGDFLFLSAHHLVVDGISWRVLLEDLALGYRQAAGGGKEIQL PPKTSSFKAYTKKLSDYAESQQLMKQLKYWREAEEYQTEALPFDHIDGTRAHEGQRSTI SFTLNEKETAALLKDANSAYNTDTQDMLLASVILALRHWTNQSAFKLSLEGHGREDVLK GIDVSRTIGWFTAIYPLLIKLNADLPDSEESMVHVLKTTKDTLRRVPDKGFGYGVIKYL TPPGKKDINFTGAPEISFNYLGQFESGRTAEVPEEDAFSFSPLGAGGDISTTWNREQSL DISAIAAEGKLTVNMTYDNARFQRKTIEQLSETCRQFLLQLIEHCQNKSETEKTISDFD DQELTEDALQEIADMLSFH" aSDomain 3861..4751 /aSDomain="Condensation" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg9_2_Condensation_DCL.1" /domain_subtypes="Condensation_DCL" /evalue="3.00E-117" /label="ctg9_2_Condensation_DCL.1" /locus_tag="ctg9_2" /protein_end="304" /protein_start="7" /score="382.8" /tool="antismash" /translation="QDIYPLSYMQEGMLFHSLLQKDSQAYVEQASFTIEGKVNPQFFQN SINALVERHDIFRTIFISQNVSSPQQVVLRERNVIVLEENITHLNEAEQSQFIEQWKEK DRDQGFHLQKDVLMRIALIQTGESQYSCIWTFHHIMMDGWCLSIVLKEFLHIYASYVNA SPITLEPVQPYGKYIKWLMEQDKEQAVSYWDHYLSGHEQQTVLPKQKKTKGKSRQEHVT FSFSKEESSRLSELAAREEVTLSTIFHTIWGILLQKYNNNDDAVFGSVISGRPAEIEGI EHMVGLFINTMPVRVQ" aSModule 3861..6959 /complete /domains="nrpspksdomains_ctg9_2_Condensation_DCL.1" /domains="nrpspksdomains_ctg9_2_AMP-binding.1" /domains="nrpspksdomains_ctg9_2_PCP.1" /locus_tags="ctg9_2" /monomer_pairings="Pro -> Pro" /tool="antismash" /type="nrps" CDS_motif 3870..3911 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_2_0001" /evalue="1.90E-04" /label="C1_DCL_004-017" /locus_tag="ctg9_2" /protein_end="24" /protein_start="10" /score="13.6" /tool="antismash" /translation="YPLSYMQEGMLFHS" CDS_motif 3933..4046 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_2_0002" /evalue="2.50E-15" /label="C2_DCL_024-062" /locus_tag="ctg9_2" /protein_end="69" /protein_start="31" /score="48.7" /tool="antismash" /translation="AYVEQASFTIEGKVNPQFFQNSINALVERHDIFRTIFI" CDS_motif 4266..4331 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_2_0003" /evalue="9.90E-11" /label="C3_DCL_135-156" /locus_tag="ctg9_2" /protein_end="164" /protein_start="142" /score="34.0" /tool="antismash" /translation="FHHIMMDGWCLSIVLKEFLHIY" CDS_motif 4377..4415 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_2_0004" /evalue="2.60E-02" /label="C4_DCL_171-183" /locus_tag="ctg9_2" /protein_end="192" /protein_start="179" /score="7.7" /tool="antismash" /translation="PYGKYIKWLMEQD" CDS_motif 4650..4745 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_2_0005" /evalue="2.00E-19" /label="C5_DCL_263-294" /locus_tag="ctg9_2" /protein_end="302" /protein_start="270" /score="62.0" /tool="antismash" /translation="DAVFGSVISGRPAEIEGIEHMVGLFINTMPVR" protocluster 4683..36655 /aStool="rule-based-clusters" /category="other" /contig_edge="False" /core_location="[14682:26655]" /cutoff="10000" /detection_rule="(HMGL-like and AMP-binding)" /neighbourhood="10000" /product="betalactone" /protocluster_number="2" /tool="antismash" proto_core 14683..26655 /aStool="rule-based-clusters" /tool="antismash" /cutoff="10000" /detection_rule="(HMGL-like and AMP-binding)" /neighbourhood="10000" /product="betalactone" /protocluster_number="2" CDS_motif 4791..4907 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_2_0006" /evalue="3.60E-20" /label="C67_DCL_14fromHMM" /locus_tag="ctg9_2" /protein_end="356" /protein_start="317" /score="64.4" /tool="antismash" /translation="QKDRLAAEAYSYHPLYEIQSRSAVKQGLIDHILVFENYP" aSDomain 5244..6434 /aSDomain="AMP-binding" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg9_2_AMP-binding.1" /evalue="1.10E-104" /label="ctg9_2_AMP-binding.1" /locus_tag="ctg9_2" /protein_end="865" /protein_start="468" /score="342.1" /specificity="substrate consensus: Pro" /tool="antismash" /translation="FEKQAEKTPDAHAVIDQACSLTYRELNKAANRLARHLRMKGVVRQ EPVAIMMERSAAFITGVLGILKAGGAIVPVDPHYPADRIRYILHDCGCSHVVSQAHLPS SLEDNYIITHPEDIESKVDGSNIKSVNNADDLLYMIYTSGTTGKPKGVQFEHRNMANLL KFEYTHSGIDFEADVLQFATPSFDVCYQEIFSALLKGGTLHIVPEAIKRDVPQLFAFIN KHQTNIVFLPTAFIKMIFSERELANSFPDGVKHLIAAGEQLMISDLFQDVLRKRGIHLH NHYGPSETHVVSTYTIHPGDPIPELPPIGKPIGCTDLYILNHQKQLQPCGVPGELYISG ASVARGYVNHDKLTSDKFSSDPFKPDVIMYRTGDLARRLEDGNIEYIGRADNQVKIR" CDS_motif 5430..5471 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_2_0007" /evalue="1.10E-03" /label="NRPS-A_a2" /locus_tag="ctg9_2" /protein_end="544" /protein_start="530" /score="12.5" /tool="antismash" /translation="LGILKAGGAIVPVD" CDS_motif 5655..5711 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_2_0008" /evalue="2.80E-08" /label="NRPS-A_a3" /locus_tag="ctg9_2" /protein_end="624" /protein_start="605" /score="26.0" /tool="antismash" /translation="YMIYTSGTTGKPKGVQFEH" CDS_motif 6093..6119 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_2_0009" /evalue="9.00E-01" /label="NRPS-A_a5" /locus_tag="ctg9_2" /protein_end="760" /protein_start="751" /score="3.2" /tool="antismash" /translation="YGPSETHVV" CDS_motif 6228..6317 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_2_0010" /evalue="1.30E-12" /label="NRPS-A_a6" /locus_tag="ctg9_2" /protein_end="826" /protein_start="796" /score="39.9" /tool="antismash" /translation="PCGVPGELYISGASVARGYVNHDKLTSDKF" CDS_motif 6399..6464 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_2_0011" /evalue="1.30E-11" /label="NRPS-A_a8" /locus_tag="ctg9_2" /protein_end="875" /protein_start="853" /score="36.5" /tool="antismash" /translation="YIGRADNQVKIRGYRIEPQEIE" CDS_motif 6672..6698 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_2_0012" /evalue="9.40E-01" /label="NRPS-A_a10" /locus_tag="ctg9_2" /protein_end="953" /protein_start="944" /score="3.1" /tool="antismash" /translation="GKVDRAALP" aSDomain 6753..6959 /aSDomain="PCP" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg9_2_PCP.1" /evalue="2.00E-23" /label="ctg9_2_PCP.1" /locus_tag="ctg9_2" /protein_end="1040" /protein_start="971" /score="74.3" /tool="antismash" /translation="EAKLSQLFEDVLKNGHIGIQDNFFDNGGHSLKATVLMSRIAKEFH VQVSLKDIFAHPTVEGLALIIREA" aSDomain 7002..7838 /aSDomain="Condensation" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg9_2_Condensation_LCL.1" /domain_subtypes="Condensation_LCL" /evalue="2.40E-101" /label="ctg9_2_Condensation_LCL.1" /locus_tag="ctg9_2" /protein_end="1333" /protein_start="1054" /score="330.5" /tool="antismash" /translation="DTYPVSSAQKRIYVLQQLDEGVAYNMPAVLELEGALDVAKLSAVC KELISRHEPLRTSFVSGADDEPVQRIHTEVPFTLSKETTIEGFVRPFCLSQAPLFRAGL IEVSNEKHVLLVDMHHIISDGVSVQLLIREFTDLYANRQLKPLRIQYKDYAVWQQKFKK GDSYQKQETYWQQQFSGDLPILELPTDKRRPAERQFIGGKVTFQLDKEITARIKRLAHK NRSTLYMTLLALYSAFLSRLSGQDDIVIGSPIAGRPHADLEAVLGMFVNTLALRTRP" aSModule 7002..10052 /complete /domains="nrpspksdomains_ctg9_2_Condensation_LCL.1" /domains="nrpspksdomains_ctg9_2_AMP-binding.2" /domains="nrpspksdomains_ctg9_2_PCP.2" /locus_tags="ctg9_2" /monomer_pairings="Glu -> Glu" /tool="antismash" /type="nrps" CDS_motif 7068..7181 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_2_0013" /evalue="1.30E-14" /label="C2_LCL_024-062" /locus_tag="ctg9_2" /protein_end="1114" /protein_start="1076" /score="46.5" /tool="antismash" /translation="AYNMPAVLELEGALDVAKLSAVCKELISRHEPLRTSFV" CDS_motif 7353..7418 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_2_0014" /evalue="3.40E-09" /label="C3_LCL_132-143" /locus_tag="ctg9_2" /protein_end="1193" /protein_start="1171" /score="29.2" /tool="antismash" /translation="MHHIISDGVSVQLLIREFTDLY" CDS_motif 7449..7481 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_2_0015" /evalue="6.40E-04" /label="C4_LCL_164-176" /locus_tag="ctg9_2" /protein_end="1214" /protein_start="1203" /score="12.5" /tool="antismash" /translation="QYKDYAVWQQK" CDS_motif 7740..7829 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_2_0016" /evalue="5.00E-16" /label="C5_LCL_267-296" /locus_tag="ctg9_2" /protein_end="1330" /protein_start="1300" /score="51.0" /tool="antismash" /translation="DIVIGSPIAGRPHADLEAVLGMFVNTLALR" CDS_motif 7878..7997 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_2_0017" /evalue="1.20E-20" /label="C67_LCL_14fromHMM" /locus_tag="ctg9_2" /protein_end="1386" /protein_start="1346" /score="65.9" /tool="antismash" /translation="RQTALEAYEHQDYPFEELVDKLGVQREMSRNPLFDTTLVL" aSDomain 8337..9539 /aSDomain="AMP-binding" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg9_2_AMP-binding.2" /evalue="9.90E-113" /label="ctg9_2_AMP-binding.2" /locus_tag="ctg9_2" /protein_end="1900" /protein_start="1499" /score="368.6" /specificity="substrate consensus: Glu" /tool="antismash" /translation="LEQQAEKTPDQAAVIFEDGVMTYKELNEQANRIAWELIGRGVKPE TTVAIIGKRSPEMLLGIYGILKAGGAYLPIDPDYPEERISFLLEDSGTNILLLQSAGLH VPAFTGEIVYLNQTNSGLAHRLSNPNVDVLPQSLAYVIYTSGSTGMPKGVEIEHRSAVN FLNSLQSRYQLKHSDMIMHKTSYSFDASIWELFWWPYAGASVYLLPQGGEKEPEVIAKA IEEQKITAMHFVPSMLHAFLEHIKYRSVPIKTNRLKRVFSGGEQLGTHLVSRFYELLPN VSITNSYGPTEATVEAAFFDCPPQEKLERIPIGKPVHHVRLYILNQNQRMLPVGCIGEL YIAGAGVARGYLNRPALTEERFLEDPFYPGERMYKTGDVARWLPDGNIEFLGRTDDQVK IR" CDS_motif 8526..8564 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_2_0018" /evalue="1.60E-04" /label="NRPS-A_a2" /locus_tag="ctg9_2" /protein_end="1575" /protein_start="1562" /score="15.0" /tool="antismash" /translation="GILKAGGAYLPID" CDS_motif 8751..8810 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_2_0019" /evalue="1.90E-09" /label="NRPS-A_a3" /locus_tag="ctg9_2" /protein_end="1657" /protein_start="1637" /score="29.5" /tool="antismash" /translation="AYVIYTSGSTGMPKGVEIEH" CDS_motif 9195..9224 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_2_0020" /evalue="8.60E-02" /label="NRPS-A_a5" /locus_tag="ctg9_2" /protein_end="1795" /protein_start="1785" /score="6.1" /tool="antismash" /translation="SYGPTEATVE" CDS_motif 9333..9422 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_2_0021" /evalue="3.40E-18" /label="NRPS-A_a6" /locus_tag="ctg9_2" /protein_end="1861" /protein_start="1831" /score="57.7" /tool="antismash" /translation="PVGCIGELYIAGAGVARGYLNRPALTEERF" CDS_motif 9504..9569 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_2_0022" /evalue="2.30E-12" /label="NRPS-A_a8" /locus_tag="ctg9_2" /protein_end="1910" /protein_start="1888" /score="38.8" /tool="antismash" /translation="FLGRTDDQVKIRGYRIEPGEIE" CDS_motif 9765..9791 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_2_0023" /evalue="1.00E+00" /label="NRPS-A_a10" /locus_tag="ctg9_2" /protein_end="1984" /protein_start="1975" /score="3.0" /tool="antismash" /translation="GKLDRNALP" aSDomain 9846..10052 /aSDomain="PCP" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg9_2_PCP.2" /evalue="2.10E-25" /label="ctg9_2_PCP.2" /locus_tag="ctg9_2" /protein_end="2071" /protein_start="2002" /score="80.6" /tool="antismash" /translation="EMKLSQLWEDVLKNGPVGIHDNFFDRGGHSLKATALVSRITKEFD VQVPLKDVFAHPTVEGLAAVIREG" aSDomain 10095..10958 /aSDomain="Condensation" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg9_2_Condensation_LCL.2" /domain_subtypes="Condensation_LCL" /evalue="5.40E-110" /label="ctg9_2_Condensation_LCL.2" /locus_tag="ctg9_2" /protein_end="2373" /protein_start="2085" /score="358.9" /tool="antismash" /translation="ETYPVSSAQKRIYVLQQLEDGGTGYNMPAVLELEGKLNPERMDRA FKELIKRHESLRTSFEQDAGGDPVQRIHDEVPFTLQTTVLGERTEQEAAAAFIKPFDLS QAPLFRAQIVKVSDERHLLLVDMHHIISDGVSVNILIREFGELYNNRNLPALRIQYKDY AVWQEGFKTRDAYKTQGAYWLKQLEGELPVLDLPADHVRPPVRSFAGDKVSFTLDQEVA SDLHKLARENGSTLYMVLLAAYTAFLSRLSGQEDIIVGSPIAGRPHKDLEPILGMFVNT LALRTRP" aSModule 10095..14630 /complete /domains="nrpspksdomains_ctg9_2_Condensation_LCL.2" /domains="nrpspksdomains_ctg9_2_AMP-binding.3" /domains="nrpspksdomains_ctg9_2_PCP.3" /domains="nrpspksdomains_ctg9_2_Epimerization.1" /domains="nrpspksdomains_ctg9_2_TIGR01720.1" /locus_tags="ctg9_2" /monomer_pairings="Tyr -> D-Tyr" /tool="antismash" /type="nrps" CDS_motif 10167..10274 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_2_0024" /evalue="2.00E-16" /label="C2_LCL_024-062" /locus_tag="ctg9_2" /protein_end="2145" /protein_start="2109" /score="52.3" /tool="antismash" /translation="YNMPAVLELEGKLNPERMDRAFKELIKRHESLRTSF" CDS_motif 10473..10538 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_2_0025" /evalue="1.40E-09" /label="C3_LCL_132-143" /locus_tag="ctg9_2" /protein_end="2233" /protein_start="2211" /score="30.4" /tool="antismash" /translation="MHHIISDGVSVNILIREFGELY" CDS_motif 10569..10598 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_2_0026" /evalue="3.70E-04" /label="C4_LCL_164-176" /locus_tag="ctg9_2" /protein_end="2253" /protein_start="2243" /score="13.2" /tool="antismash" /translation="QYKDYAVWQE" CDS_motif 10860..10949 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_2_0027" /evalue="4.30E-15" /label="C5_LCL_267-296" /locus_tag="ctg9_2" /protein_end="2370" /protein_start="2340" /score="48.0" /tool="antismash" /translation="DIIVGSPIAGRPHKDLEPILGMFVNTLALR" CDS_motif 10998..11114 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_2_0028" /evalue="1.20E-19" /label="C67_LCL_14fromHMM" /locus_tag="ctg9_2" /protein_end="2425" /protein_start="2386" /score="62.7" /tool="antismash" /translation="RETALEAFEHQDYPFEELVDKLELTRDMSRNPVFDAMLV" aSDomain 11454..12635 /aSDomain="AMP-binding" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg9_2_AMP-binding.3" /evalue="1.00E-112" /label="ctg9_2_AMP-binding.3" /locus_tag="ctg9_2" /protein_end="2932" /protein_start="2538" /score="368.6" /specificity="substrate consensus: Tyr" /tool="antismash" /translation="FEQQAARTPKATALVSGDKTLTYQELDEWSNGIARALRNRGVKPD TPVGIMMHRSFSMIASILGVWKAGGCYVPIDPEYPKERKRYILSDSGTKLLMTINEADL GVLADFEGEILTIESVEEDDKSPLPQMSSAHHLAYIIYTSGTTGRPKGVMVEHKGIANT LQWRRNAYAFNETDTILQLFSFSFDGFITSMFTPLLSGAKAVLLHEEEAKDILAIKHQL SRQRITHMIIVPVLYRALLDVVQPEDVKTLRVVTLAGEAADRELIARSLAICPHTELAN EYGPTENSVATTVMRHMEKQAYVSIGQPIDGTQVLILNSNHQLQPIGVAGELCIAGTGL ARGYVNLPELTERAFTQNPFKPEARMYRTGDAARWMADGTLEYLGRIDDQVKIR" CDS_motif 11640..11681 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_2_0029" /evalue="3.80E-05" /label="NRPS-A_a2" /locus_tag="ctg9_2" /protein_end="2614" /protein_start="2600" /score="16.9" /tool="antismash" /translation="LGVWKAGGCYVPID" CDS_motif 11865..11924 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_2_0030" /evalue="9.60E-11" /label="NRPS-A_a3" /locus_tag="ctg9_2" /protein_end="2695" /protein_start="2675" /score="33.4" /tool="antismash" /translation="AYIIYTSGTTGRPKGVMVEH" CDS_motif 12297..12329 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_2_0031" /evalue="1.80E-01" /label="NRPS-A_a5" /locus_tag="ctg9_2" /protein_end="2830" /protein_start="2819" /score="5.2" /tool="antismash" /translation="EYGPTENSVAT" CDS_motif 12429..12518 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_2_0032" /evalue="8.70E-15" /label="NRPS-A_a6" /locus_tag="ctg9_2" /protein_end="2893" /protein_start="2863" /score="46.8" /tool="antismash" /translation="PIGVAGELCIAGTGLARGYVNLPELTERAF" CDS_motif 12600..12665 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_2_0033" /evalue="1.10E-10" /label="NRPS-A_a8" /locus_tag="ctg9_2" /protein_end="2942" /protein_start="2920" /score="33.5" /tool="antismash" /translation="YLGRIDDQVKIRGYRVETKEIE" CDS_motif 12873..12899 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_2_0034" /evalue="3.40E+00" /label="NRPS-A_a10" /locus_tag="ctg9_2" /protein_end="3020" /protein_start="3011" /score="1.6" /tool="antismash" /translation="GKLDRGALP" aSDomain 12957..13157 /aSDomain="PCP" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg9_2_PCP.3" /evalue="5.90E-27" /label="ctg9_2_PCP.3" /locus_tag="ctg9_2" /protein_end="3106" /protein_start="3039" /score="85.6" /tool="antismash" /translation="EQILADIWKEVLGAEKIGTADSFFELGGDSIKALQVSARLHRIGK QMAVKDLFSHPTIQELAAYIRD" aSDomain 13188..14126 /aSDomain="Epimerization" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg9_2_Epimerization.1" /evalue="3.40E-152" /label="ctg9_2_Epimerization.1" /locus_tag="ctg9_2" /protein_end="3429" /protein_start="3116" /score="499.8" /tool="antismash" /translation="EGDVQWSPVQKWFLSQDIKEKHHFNQSVMLHRSTSVQEDALRKTL KAITCHHDALRMVFTQNEQGKWDQYNRPLSHSDDALYGLQMIDLSAPDGTDGNRAYEPI IKRHVLDIQQKMDLKNGPLLQAGLFHTIDGDFLFLSAHHLVVDGISWRVLLEDLALGYR QAAGGGKEIQLPPKTSSFKAYTKKLSDYAESQQLMKQLKYWREAEEYQTEALPFDHIDG TRAHEGQRSTISFTLNEKETAALLKDANSAYNTDTQDMLLASVILALRHWTNQSAFKLS LEGHGREDVLKGIDVSRTIGWFTAIYPLLIKL" CDS_motif 13338..13379 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_2_0035" /evalue="3.30E-03" /label="Cy2" /locus_tag="ctg9_2" /protein_end="3180" /protein_start="3166" /score="10.2" /tool="antismash" /translation="HHDALRMVFTQNEQ" CDS_motif 13596..13661 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_2_0036" /evalue="7.10E-11" /label="NRPS-E2" /locus_tag="ctg9_2" /protein_end="3274" /protein_start="3252" /score="34.3" /tool="antismash" /translation="LFLSAHHLVVDGISWRVLLEDL" CDS_motif 14070..14117 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_2_0037" /evalue="1.60E-07" /label="NRPS-E5" /locus_tag="ctg9_2" /protein_end="3426" /protein_start="3410" /score="23.5" /tool="antismash" /translation="DVSRTIGWFTAIYPLL" aSDomain 14163..14630 /aSDomain="TIGR01720" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg9_2_TIGR01720.1" /evalue="2.50E-45" /label="ctg9_2_TIGR01720.1" /locus_tag="ctg9_2" /protein_end="3597" /protein_start="3441" /score="145.9" /tool="antismash" /translation="HVLKTTKDTLRRVPDKGFGYGVIKYLTPPGKKDINFTGAPEISFN YLGQFESGRTAEVPEEDAFSFSPLGAGGDISTTWNREQSLDISAIAAEGKLTVNMTYDN ARFQRKTIEQLSETCRQFLLQLIEHCQNKSETEKTISDFDDQELTEDALQEI" CDS_motif 14178..14240 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_2_0038" /evalue="3.20E-09" /label="NRPS-E6" /locus_tag="ctg9_2" /protein_end="3467" /protein_start="3446" /score="29.0" /tool="antismash" /translation="TKDTLRRVPDKGFGYGVIKYL" CDS 14683..18501 /NRPS_PKS="Domain: NRPS-COM_Nterm (1-29). E-value: 3.5e-15. Score: 46.9. Matches aSDomain: nrpspksdomains_ctg9_3_NRPS-COM_Nterm.1" /NRPS_PKS="Domain: Condensation_DCL (8-309). E-value: 3.6e-119. Score: 389.2. Matches aSDomain: nrpspksdomains_ctg9_3_Condensation_DCL.1" /NRPS_PKS="Domain: AMP-binding (474-867). E-value: 5.8e-110. Score: 359.5. Matches aSDomain: nrpspksdomains_ctg9_3_AMP-binding.1" /NRPS_PKS="Domain: PCP (973-1040). E-value: 3.3e-23. Score: 73.6. Matches aSDomain: nrpspksdomains_ctg9_3_PCP.1" /NRPS_PKS="Domain: Thioesterase (1060-1264). E-value: 4.1e-41. Score: 133.7. Matches aSDomain: nrpspksdomains_ctg9_3_Thioesterase.1" /gene_functions="biosynthetic (rule-based-clusters) NRPS: Condensation" /gene_functions="biosynthetic (rule-based-clusters) NRPS: AMP-binding" /gene_functions="biosynthetic (rule-based-clusters) betalactone: AMP-binding" /gene_functions="biosynthetic-additional (rule-based-clusters) PP-binding" /gene_functions="biosynthetic-additional (smcogs) SMCOG1002:AMP-dependent synthetase and ligase (Score: 340.5; E-value: 2.3e-103)" /gene_kind="biosynthetic" /locus_tag="ctg9_3" /sec_met_domain="Condensation (E-value: 9.9e-90, bitscore: 292.8, seeds: 42, tool: rule-based-clusters)" /sec_met_domain="AMP-binding (E-value: 4.8e-114, bitscore: 373.3, seeds: 400, tool: rule-based-clusters)" /sec_met_domain="PP-binding (E-value: 5.6e-17, bitscore: 54.3, seeds: 164, tool: rule-based-clusters)" /transl_table=11 /translation="MNTIKKIKNIYPLSHMQEGMLFHSFLRKEEGAYVEQSLFTIKGSL SYDWFQRSIQAIIDRHDIFRTVFLPHVPHLSGPRQVVMTEREFHLNSEDISHLPTNDQN EYIERFKEKDKQKGFDLQKDMLMRISLFKTAKDEHVCIWSHHHILMDGWCLGIVMQEFM QIYQSIHAGKPLSLDPVRPYSTYISWLTNRDKEKAAAYWDTYLKNYSAPSPLPRVSDKE TKEGYHREDLIFSLNKPLTDKLKETAKQHGVTLATLIQAVWGVMLQQYNRTDDVVFGAV VSGRPSEIPGVEQMIGLFINTIPIRIKTHQDETFHELLIRCQKEMLEAEPFTCQPLFDI QANTALKQELIDHIIVFENYPLQQKIADSADQTDSPLQIDQVQVSEQSGYNFNLVVAPG EELVIKFSYNAFVYDAAWISCIKRQFTQALSTAAQHPHMPIADFSFLDATEKEQIVTQF NNTKTEYPKNHTIIDLFREQAEKTPDHTALVYGNMSISYKELDKRSNALARELIQKGFR QNETAGILAAHSPEFMISVLAVLKAGGAYLPLDAELPPERVSFMLEETQAKMLIVQKGL EQNAAFSGTCMIADAQALMEENHFPINSSSSPDDLAYIMYTSGSTGRPKGVMITNRNVV SLVSNSNYTSASGDDRFIMTGSISFDAVTFEMFGALLNGASLHIIDKSTMLTPDRFGAY LLENDITVLFLTTALFNQLAQVRADMFRGLHTLYVGGEALSPALMNAVRHACPDLALHN IYGPTENTTFSTFFEIKRDYAGPIPIGKPISNSTTYILDTKGRLLPIGVPGELCVGGDG VAKGYLNRDDLTNALFSPHPFLPGERIYRTGDLARWLPDGNLEYISRIDRQMKIRGKRI EPAEIEARLLEMEGVQEAAVTLREKDGEAQLYTHYVGDHKKTDTDFRADLARVLPDYMI PQHWVRVERMPLTGNGKIDRSALPIPENKPAKRQDIILPRNLVEEELANIWKQVLGVNT ISIDDDFFAIGGHSLKALQVIHTLKHQQNIDIPIDFLFEHPTIAQLAEKLYSKQLTAAN EQHVIKLNQHGAQNLFCFPPISGFGIYFKDLALLLNEKAALYGFHFIEQDTRIEQYVNC MTDIQPEGPYVLLGYSAGGNLAFEVAQAMERKGLEVSDFIIVDAYLKEQPLPIDTGNDE SAAYLPEAVREKVMKKKRNYQEYWAQLLNEGHIKASIHFIEAGIHPETSGHTGLTKWEG ACGNYSEYTGFGAHKDMLEGTYAEKNADIILDILEKITSNQVILHKR" aSDomain 14686..14769 /aSDomain="NRPS-COM_Nterm" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg9_3_NRPS-COM_Nterm.1" /evalue="3.50E-15" /label="ctg9_3_NRPS-COM_Nterm.1" /locus_tag="ctg9_3" /protein_end="29" /protein_start="1" /score="46.9" /tool="antismash" /translation="NTIKKIKNIYPLSHMQEGMLFHSFLRKE" aSDomain 14707..15609 /aSDomain="Condensation" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg9_3_Condensation_DCL.1" /domain_subtypes="Condensation_DCL" /evalue="3.60E-119" /label="ctg9_3_Condensation_DCL.1" /locus_tag="ctg9_3" /protein_end="309" /protein_start="8" /score="389.2" /tool="antismash" /translation="NIYPLSHMQEGMLFHSFLRKEEGAYVEQSLFTIKGSLSYDWFQRS IQAIIDRHDIFRTVFLPHVPHLSGPRQVVMTEREFHLNSEDISHLPTNDQNEYIERFKE KDKQKGFDLQKDMLMRISLFKTAKDEHVCIWSHHHILMDGWCLGIVMQEFMQIYQSIHA GKPLSLDPVRPYSTYISWLTNRDKEKAAAYWDTYLKNYSAPSPLPRVSDKETKEGYHRE DLIFSLNKPLTDKLKETAKQHGVTLATLIQAVWGVMLQQYNRTDDVVFGAVVSGRPSEI PGVEQMIGLFINTIPIRIKT" aSModule 14707..18474 /complete /domains="nrpspksdomains_ctg9_3_Condensation_DCL.1" /domains="nrpspksdomains_ctg9_3_AMP-binding.1" /domains="nrpspksdomains_ctg9_3_PCP.1" /domains="nrpspksdomains_ctg9_3_Thioesterase.1" /final_module /locus_tags="ctg9_3" /monomer_pairings="Ile -> Ile" /tool="antismash" /type="nrps" CDS_motif 14713..14754 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_3_0001" /evalue="3.90E-05" /label="C1_DCL_004-017" /locus_tag="ctg9_3" /protein_end="24" /protein_start="10" /score="15.5" /tool="antismash" /translation="YPLSHMQEGMLFHS" CDS_motif 14773..14889 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_3_0002" /evalue="1.20E-15" /label="C2_DCL_024-062" /locus_tag="ctg9_3" /protein_end="69" /protein_start="30" /score="49.7" /tool="antismash" /translation="GAYVEQSLFTIKGSLSYDWFQRSIQAIIDRHDIFRTVFL" CDS_motif 15115..15180 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_3_0003" /evalue="1.00E-12" /label="C3_DCL_135-156" /locus_tag="ctg9_3" /protein_end="166" /protein_start="144" /score="40.4" /tool="antismash" /translation="HHHILMDGWCLGIVMQEFMQIY" CDS_motif 15505..15600 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_3_0004" /evalue="1.30E-21" /label="C5_DCL_263-294" /locus_tag="ctg9_3" /protein_end="306" /protein_start="274" /score="69.0" /tool="antismash" /translation="DVVFGAVVSGRPSEIPGVEQMIGLFINTIPIR" CDS_motif 15649..15765 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_3_0005" /evalue="1.40E-16" /label="C67_DCL_14fromHMM" /locus_tag="ctg9_3" /protein_end="361" /protein_start="322" /score="52.9" /tool="antismash" /translation="QKEMLEAEPFTCQPLFDIQANTALKQELIDHIIVFENYP" aSDomain 16105..17283 /aSDomain="AMP-binding" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg9_3_AMP-binding.1" /evalue="5.80E-110" /label="ctg9_3_AMP-binding.1" /locus_tag="ctg9_3" /protein_end="867" /protein_start="474" /score="359.5" /specificity="substrate consensus: Ile" /tool="antismash" /translation="FREQAEKTPDHTALVYGNMSISYKELDKRSNALARELIQKGFRQN ETAGILAAHSPEFMISVLAVLKAGGAYLPLDAELPPERVSFMLEETQAKMLIVQKGLEQ NAAFSGTCMIADAQALMEENHFPINSSSSPDDLAYIMYTSGSTGRPKGVMITNRNVVSL VSNSNYTSASGDDRFIMTGSISFDAVTFEMFGALLNGASLHIIDKSTMLTPDRFGAYLL ENDITVLFLTTALFNQLAQVRADMFRGLHTLYVGGEALSPALMNAVRHACPDLALHNIY GPTENTTFSTFFEIKRDYAGPIPIGKPISNSTTYILDTKGRLLPIGVPGELCVGGDGVA KGYLNRDDLTNALFSPHPFLPGERIYRTGDLARWLPDGNLEYISRIDRQMKIR" CDS_motif 16291..16332 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_3_0006" /evalue="8.20E-06" /label="NRPS-A_a2" /locus_tag="ctg9_3" /protein_end="550" /protein_start="536" /score="18.9" /tool="antismash" /translation="LAVLKAGGAYLPLD" CDS_motif 16516..16572 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_3_0007" /evalue="4.40E-10" /label="NRPS-A_a3" /locus_tag="ctg9_3" /protein_end="630" /protein_start="611" /score="31.4" /tool="antismash" /translation="AYIMYTSGSTGRPKGVMIT" CDS_motif 17077..17163 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_3_0008" /evalue="3.80E-15" /label="NRPS-A_a6" /locus_tag="ctg9_3" /protein_end="827" /protein_start="798" /score="48.0" /tool="antismash" /translation="PIGVPGELCVGGDGVAKGYLNRDDLTNAL" CDS_motif 17248..17313 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_3_0009" /evalue="1.30E-09" /label="NRPS-A_a8" /locus_tag="ctg9_3" /protein_end="877" /protein_start="855" /score="30.2" /tool="antismash" /translation="YISRIDRQMKIRGKRIEPAEIE" aSDomain 17602..17802 /aSDomain="PCP" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg9_3_PCP.1" /evalue="3.30E-23" /label="ctg9_3_PCP.1" /locus_tag="ctg9_3" /protein_end="1040" /protein_start="973" /score="73.6" /tool="antismash" /translation="EEELANIWKQVLGVNTISIDDDFFAIGGHSLKALQVIHTLKHQQN IDIPIDFLFEHPTIAQLAEKLY" aSDomain 17863..18474 /aSDomain="Thioesterase" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg9_3_Thioesterase.1" /evalue="4.10E-41" /label="ctg9_3_Thioesterase.1" /locus_tag="ctg9_3" /protein_end="1264" /protein_start="1060" /score="133.7" /tool="antismash" /translation="QNLFCFPPISGFGIYFKDLALLLNEKAALYGFHFIEQDTRIEQYV NCMTDIQPEGPYVLLGYSAGGNLAFEVAQAMERKGLEVSDFIIVDAYLKEQPLPIDTGN DESAAYLPEAVREKVMKKKRNYQEYWAQLLNEGHIKASIHFIEAGIHPETSGHTGLTKW EGACGNYSEYTGFGAHKDMLEGTYAEKNADIILDILEKITS" CDS_motif 18016..18087 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_3_0010" /evalue="3.10E-13" /label="NRPS-te1" /locus_tag="ctg9_3" /protein_end="1135" /protein_start="1111" /score="42.0" /tool="antismash" /translation="QPEGPYVLLGYSAGGNLAFEVAQA" CDS 18611..19003 /locus_tag="ctg9_4" /transl_table=11 /translation="MDRLSFLTFIMLILASYRLTHLIVFDKITEFIRKPFMKKKRIVDQ NGHVDEKSVPASNFGYMLNCYWCAGVWCAILIGLGYLFLPRIAIPLIFILAIAGAQAIL ETAVGVGVKLIDVLKSLQTMMNDKKS" CDS 19136..20668 /locus_tag="ctg9_5" /transl_table=11 /translation="MKVCQKSIVRFLVSLIIGTFVISVPFMANAQSDRELRAVWIASVL NIDWPSKKGLSVKEQKQEYIKLLDDVQKMGMNAVIVQIKPMADAFYPSAYGPWSEYLTG VQGKDPGYDPLAFIIKETHKRNLEFHAWFNPYRITMNHTDLNKLSEDHPARKHPDWVAA YGNQLYYHPGIPEARDFIVKGIEEVVKHYDIDAVHMDDYFYPYKIAGQEFPDQAQYEQY GKGAFSNIDDWRRDNVNQLVKQINQTIKAAKPYVKFGISPFGVWRNAADDPTGSNTKAG VRNYDDLYADTRHWIQEGDIDYIAPQIYWSIGFNAAAYDVLADWWSNEVKNRPVHLYIG QAAYKINNNFDPPWSDPEEYVRQITLNRQLELVKGSMHFSLKDLNKNPLSIKDRLSTDL YSKPALVPQMPWLDNTAPKKPKLTKVTEDKNGNLLQIKDHPSNLKTKETAYYAIYRAEG KKQRTLLATQRKTHEQQTFLDNTADPNKKYTYYVTSADRLHNESKASKRTTK" CDS 20779..20940 /locus_tag="ctg9_6" /transl_table=11 /translation="MEAVFRHFPLLESEKLVLNKIEEKHVQDVFYVFISSLVRCHIIFC AVRRCCVD" CDS 21326..22468 /gene_functions="biosynthetic-additional (rule-based-clusters) Acyl-CoA_dh_N" /gene_functions="biosynthetic-additional (rule-based-clusters) Acyl-CoA_dh_M" /gene_functions="biosynthetic-additional (rule-based-clusters) Acyl-CoA_dh_1" /gene_functions="biosynthetic-additional (smcogs) SMCOG1006:acyl-CoA dehydrogenase (Score: 458.4; E-value: 3.1e-139)" /gene_kind="biosynthetic-additional" /locus_tag="ctg9_7" /sec_met_domain="Acyl-CoA_dh_N (E-value: 5.4e-40, bitscore: 128.8, seeds: 790, tool: rule-based-clusters)" /sec_met_domain="Acyl-CoA_dh_M (E-value: 1.3e-28, bitscore: 91.4, seeds: 43, tool: rule-based-clusters)" /sec_met_domain="Acyl-CoA_dh_1 (E-value: 6.1e-56, bitscore: 181.0, seeds: 49, tool: rule-based-clusters)" /transl_table=11 /translation="MNFELTKEQQMVREMVKDFAKKEIAPHAEHVDQTGEFPMQTFEKM GELGLMGIPFPEEYGGSGGDTISYALAVEEVGKACGSTGLSYAAAVSLGASPLYYFGTE EQKQTHLTPLASGTALGSFGLTEPNAGSDAGGTQTKAISNGDEYVINGEKCWITNASYA RTVIVTAVTGKNKDGKNIISALIVPTDTPGLTITSPYDKMGVRGSNTAEILLEDVRVPA ANLLGDPTKGFKQFLYTLDGGRISIAALAVGIAQAALDASLAYAKERKQFGQPISSFQA IQFKLADMAMEIDLARQMVLKAAWLKDHNRPFTKEAAYAKLFASEMATRACNQAIQIHG GSGYMKEYGVERMLRDAKLMEIGEGTSEIQRLVIARQLLK" CDS 22512..24161 /NRPS_PKS="Domain: AMP-binding (13-445). E-value: 3.1e-106. Score: 347.2. Matches aSDomain: nrpspksdomains_ctg9_8_AMP-binding.1" /gene_functions="biosynthetic (rule-based-clusters) betalactone: AMP-binding" /gene_functions="biosynthetic-additional (smcogs) SMCOG1002:AMP-dependent synthetase and ligase (Score: 460.6; E-value: 9e-140)" /gene_kind="biosynthetic" /locus_tag="ctg9_8" /sec_met_domain="AMP-binding (E-value: 1.9e-116, bitscore: 381.2, seeds: 400, tool: rule-based-clusters)" /transl_table=11 /translation="MAELIHSTIGRLLEQTADAYPDRDAVVYPDRNIRYTYAQFDSLCR QTAKGLMRMGIGKGDHVAIWASNIPEWLAVQFATAKIGAVLVTVNTNYQAHELDYLLKQ SDAAALIIMDSYRGTSYPDIVNSLIPELQEAKPGQLKSERYPFLKTLLYIGNKRLPGMY HWDDTEILAKTVTDAELEERMNSLDKDNVINMQYTSGTTGFPKGVMLTHFNVINNAANI AECMALTSQDRMCIPVPFFHCFGCVLGVLACVSVGAAMIPVQEFDPVTVLKTVEKEKCT ALHGVPTMFIAELHHPDFDAYDLSTLRTGIMAGSPCPSEVMKAVIERMGMKDITIAYGQ TEASPVITQTRANDSFIRRVETTGRALPHTEVKIVEPGTCQEVQRGVQGELCTRGYHVM KGYYKDKEATRKAINHDGWLFTGDLAVMDEDGYCRITGRLKDMLIRGGENIYPREIEEF LYRHPAVLDVQVVGVPDAKFGEEAAAWIKLKDGKSVSPDELKAYCKGKIARHKIPRYVI FTDDYPMTASGKIQKYKLREKTIEMFNLSSSQ" aSDomain 22551..23846 /aSDomain="AMP-binding" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg9_8_AMP-binding.1" /evalue="3.10E-106" /label="ctg9_8_AMP-binding.1" /locus_tag="ctg9_8" /protein_end="445" /protein_start="13" /score="347.2" /specificity="substrate consensus: X" /tool="antismash" /translation="EQTADAYPDRDAVVYPDRNIRYTYAQFDSLCRQTAKGLMRMGIGK GDHVAIWASNIPEWLAVQFATAKIGAVLVTVNTNYQAHELDYLLKQSDAAALIIMDSYR GTSYPDIVNSLIPELQEAKPGQLKSERYPFLKTLLYIGNKRLPGMYHWDDTEILAKTVT DAELEERMNSLDKDNVINMQYTSGTTGFPKGVMLTHFNVINNAANIAECMALTSQDRMC IPVPFFHCFGCVLGVLACVSVGAAMIPVQEFDPVTVLKTVEKEKCTALHGVPTMFIAEL HHPDFDAYDLSTLRTGIMAGSPCPSEVMKAVIERMGMKDITIAYGQTEASPVITQTRAN DSFIRRVETTGRALPHTEVKIVEPGTCQEVQRGVQGELCTRGYHVMKGYYKDKEATRKA INHDGWLFTGDLAVMDEDGYCRITGRLKDMLIR" CDS_motif 23097..23147 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_8_0001" /evalue="2.10E-07" /label="NRPS-A_a3" /locus_tag="ctg9_8" /protein_end="212" /protein_start="195" /score="23.3" /tool="antismash" /translation="QYTSGTTGFPKGVMLTH" CDS_motif 23667..23744 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg9_8_0002" /evalue="5.10E-05" /label="NRPS-A_a6" /locus_tag="ctg9_8" /protein_end="411" /protein_start="385" /score="15.7" /tool="antismash" /translation="GVQGELCTRGYHVMKGYYKDKEATRK" CDS 24171..25505 /gene_functions="biosynthetic-additional (rule-based-clusters) Dala_Dala_lig_C" /gene_functions="biosynthetic-additional (rule-based-clusters) ATP-grasp" /gene_functions="biosynthetic-additional (smcogs) SMCOG1090:acetyl-CoA carboxylase biotin carboxylase (Score: 655.3; E-value: 1.9e-198)" /gene_kind="biosynthetic-additional" /locus_tag="ctg9_9" /sec_met_domain="Dala_Dala_lig_C (E-value: 2.5e-17, bitscore: 55.2, seeds: 12, tool: rule-based-clusters)" /sec_met_domain="ATP-grasp (E-value: 2.1e-10, bitscore: 32.6, seeds: 20, tool: rule-based-clusters)" /transl_table=11 /translation="MFTKVLIANRGEIAMRIIRTCSRLGIKTVAVYSEADKDAPHTKAA TEAYLIGESRVSESYLNIERIIKTAKKANADAIHPGYGLLSENSRFAERCKQENIVFIG PSPDIIEKMGSKIEARKAMEAAGVPVVPGVSESLGDIEAACRTASQIGYPVMLKASAGG GGIGMQRVENEEALKKAYEGNKKRAADFFGDGSMYIEKVIEHARHIEVQLLADQHGHTV HLFERDCSVQRRHQKVIEEAPSPFVDDELRMKIGQTAVKAAKAIGYTNAGTIEFIVDQK QNFYFLEMNTRLQVEHPVTEEITGLDLVEQQLRIAAGHTLTFSQKDIQRNGHAIEVRIY AEDPKTFFPSPGTITAFSLPDQKGVRHECAVAKDSTVTPFYDPMIAKMIVKGQTRTEAI EKLETALRDYRVEGIKTNLPLLIQAAATKAFKEGDVTTDFLKQHL" CDS 25520..25741 /locus_tag="ctg9_10" /transl_table=11 /translation="MTVSIQMAGNLWKVHVKAGDQIEKGQEVAILESMKMEIPIVADRS GIVKEVKKNEGDFVNEGDVLLELSNSTQ" CDS 25756..26655 /gene_functions="biosynthetic (rule-based-clusters) betalactone: HMGL-like" /gene_functions="biosynthetic-additional (smcogs) SMCOG1271:2-isopropylmalate synthase (Score: 268; E-value: 2.8e-81)" /gene_kind="biosynthetic" /locus_tag="ctg9_11" /sec_met_domain="HMGL-like (E-value: 8.8e-51, bitscore: 165.1, seeds: 15, tool: rule-based-clusters)" /transl_table=11 /translation="MSYPKKVTIKEVGPRDGLQNEPVWIATEDKITWINQLSRTGLSYI EITSFVHPKWIPALRDAIDVAKGIDREKGVTYAALVPNQRGLENALEGGINEACVFMSA SETHNRKNINKSTSESLHILKQVNNDAKKANLTTRAYLSTVFGCPYEKDVPIEQVIRLS EALFEFGISELSLGDTIGAANPAQVETVLEALLARFPANQIALHFHDTRGTALANMVTA LQMGITVFDGSAGGLGGCPYAPGSSGNAATEDIVYMLEQMDIKTNVKLEKLLSAAKWIE EKMGKPLPSRNLQVFKSS" CDS 26676..27458 /NRPS_PKS="Domain: ECH (10-252). E-value: 2.7e-70. Score: 228.3. Matches aSDomain: nrpspksdomains_ctg9_12_ECH.1" /gene_functions="biosynthetic-additional (smcogs) SMCOG1023:enoyl-CoA hydratase (Score: 265.8; E-value: 4.7e-81)" /gene_kind="biosynthetic-additional" /locus_tag="ctg9_12" /transl_table=11 /translation="MGNSILFTVKNEHMALITLNRPQAANALSAEMLRNLQMILQEIEF NSNIRCVILTGTGEKAFCAGADLKERIKLKEDQVLESVSLIQRTAALLDALPQPVIAAI NGSALGGGLELALACDLRIATESAVLGLPETGLAIIPGAGGTQRLPRLIGRGKAKEFIY TGRRVTAHEAKEIGLVEHVTAPCDLMPKAEELAAAISANGPIAVRQAKFAINKGLETDL ATGLAIEQKAYEQTIPTKDRREGLQAFQEKRRAVYKGI" aSDomain 26706..27431 /aSDomain="ECH" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg9_12_ECH.1" /evalue="2.70E-70" /label="ctg9_12_ECH.1" /locus_tag="ctg9_12" /protein_end="252" /protein_start="10" /score="228.3" /tool="antismash" /translation="NEHMALITLNRPQAANALSAEMLRNLQMILQEIEFNSNIRCVILT GTGEKAFCAGADLKERIKLKEDQVLESVSLIQRTAALLDALPQPVIAAINGSALGGGLE LALACDLRIATESAVLGLPETGLAIIPGAGGTQRLPRLIGRGKAKEFIYTGRRVTAHEA KEIGLVEHVTAPCDLMPKAEELAAAISANGPIAVRQAKFAINKGLETDLATGLAIEQKA YEQTIPTKDRREGLQAFQEK" CDS 27475..29004 /gene_functions="biosynthetic-additional (smcogs) SMCOG1059:acetyl-CoA carboxylase, carboxyl transferase, (Score: 547.2; E-value: 7.2e-166)" /gene_kind="biosynthetic-additional" /locus_tag="ctg9_13" /transl_table=11 /translation="MDYEKERTERAERIRKGGAEKYHQSNREKGKLFVRERLSLLFDDD IELEDAFFAECMSDGLPADGVVTGIGKIGGQTVCVMANDSTVKAGSWGAKTVEKIIRIQ ETAEKLNCPLIYLVDSAGARITDQINVFPGRRGAGRIFYNQVKLSGRIPQICLLFGPSA AGGAYIPAFCDIVVMVDGNASMYLGSPRMAEMVIGEKVSLEEMGGARMHCSISGCGDIL AETEEEAIQLARAYLSYFPANFQEKAPIHEKRPPKHFDTPLADVIPQNQNAPFDMHELI ERVIDEDSFFEIKALFAPELLTGLARIHGQPVGIVANQPKVKGGVLFHDSADKAAKFIT LCDAFHIPLLFLADIPGFMIGTKVEQAGIIRHGAKMISAMSEATVPKLSVIVRKAYGAG LYAMAGPAFEPDCCLALPTAQIAVMGPEAAVNAVYAKKIAELPEEERAAFISSKREEYK EDINIYRLASEMIIDAVIPANSLRDELAKRLKAYMTKEMTFTNRKHPVYPV" CDS 29174..30373 /locus_tag="ctg9_14" /transl_table=11 /translation="MYHLYSHNDLDGVGCGIVAKLAFGKDVEVRYNSVNGLNAQVQYFL EKAKESNRQDALFITDLAVNEENEERLNEYVHAGGKVKLIDHHKTALHLNEHEWGFVQV EYDDGRLTSATSLLYGYLVENGFMKPTNALDQFTELVRQYDTWEWERYDQKQAKRLNDL FFLLSIDEFEAKMIQRLSTHDEFFFDDFEEKLLDLEDEKIERYLRRKKREMVQTFVHEH CVGIVHAESYHSELGNRLGKDNPHLDYIAILSMGSKRVSLRTIHDYIDVSEIAGRYGGG GHAKASGCSITDEVYELFVAEAFRIDPVRPDAFRNIYNLKGSANGSLYENRAQMRFFLF PLDNEWNIQINGETQDETFAAFEEAEWFIKRNYAASLVRDEVFVAFLAENLKLANQHRK " CDS complement(30423..31019) /gene_functions="other (smcogs) SMCOG1188:hypothetical protein (Score: 144.2; E-value: 4.6e-44)" /gene_kind="other" /locus_tag="ctg9_15" /transl_table=11 /translation="MGSLISEILTWLTNMGYAGIAIGLMIEIIPSEIVLAYGGYMVSEG TIGFIGAIIAGVIGGTIAQIFIYWIGRYGGRPFLDKYGKYLLIKKHHIDMSENWFQKYG AGVVFSARFIPVVRHAISIPAGIARMPFLKFVVLTVLAIIPWSILFVYLGIQLGSQWDD VENIAGTYTTPIMILAVVVIALYFVIKKRTAIFKR" CDS complement(31092..31985) /gene_functions="biosynthetic-additional (rule-based-clusters) NTP_transf_3" /gene_functions="biosynthetic-additional (smcogs) SMCOG1064:glucose-1-phosphate adenylyl/thymidylyltransferase (Score: 230.1; E-value: 5.6e-70)" /gene_kind="biosynthetic-additional" /locus_tag="ctg9_16" /sec_met_domain="NTP_transf_3 (E-value: 1.7e-11, bitscore: 36.9, seeds: 297, tool: rule-based-clusters)" /transl_table=11 /translation="MRKKVRKAVIPAAGLGTRFLPATKAQPKEMLPIVDKPAIQYIVEE AAESGIEDILIITGRNKRSIEDHFDRSAELEFNLREKGKTETLKEMQQIADLANIHYIR QKEPLGLGHAVLCAEHFIGDEPFAVLLGDDIMVSETPALRQLMDVYDVYGTEVVGVQSV LPEDVSKYGIINTSGSQGHVYEVNDLVEKPSPEEAPSEIAVMGRYVLNSSIFSVLKTIG RGAGNEIQLTDALREVCRKEPIHARLLEGNRYDIGDKLGCFKASTEIGLMRSEMRSQLL AYLEDVIKRETKEMLR" CDS 32118..32375 /locus_tag="ctg9_17" /transl_table=11 /translation="MKQIKQQKGDPRRGNINHEKTHDLFPVSLTFHTKRPIPVPHIAVD DTCSIGADLRRQIRDMTSGKKKEDTKIYQRIADAYGAKTA" CDS 33034..34575 /locus_tag="ctg9_18" /transl_table=11 /translation="MRKKCSVCLWILVLLLSCLSGKSAYAATSTTIAKHIGNSNPLIDH HLGADPVALTYNGRVYIYMSSDDYEYNSNGTIKDNSFANLNRVFVISSADMVNWTDHGA IPVAGANGANGGRGIAKWADASWAPSIAVKKINGKDKFFLYFANSGGGIGVLTADSPIG PWTDPIGKPLVTPSTPGMSGVVWLFDPAVFVDDDGTGYLYAGGGVPGGSNPTQAQWANP KTARVIKLGPDMTSVVGSASTIDAPFMFEDSGLHKYNGTYYYSYCINFGGTHPADKPPG EIGYMTSSNPMGPFTYRGHFLKNPGAFFGGGGNNHHAVFNFKNEWYVVYHAQTVSSALF GAGKGYRSPHINKLVHNPDGSIQEVAANYAGVTQLSNLNPYNRVEAETSAWNGRILTEK STAPGGPVNNQHVTSIQNGDWIAVGNADFGAVGARSFKANVASTSGGKIEVRLDSADGK LVGTLNVPSTGGAQTWREIETAVSGATGVHKVFFVFTGTGTGNLFNFDYWQFTQR" CDS 34706..35974 /locus_tag="ctg9_19" /transl_table=11 /translation="MIPRIKKTICVLLVCFTMLSVMLGPGATEVLAASDVTVNVSAEKQ VIRGFGGMNHPAWAGDLTAAQRETAFGNGQNQLGFSILRIHVDENRNNWYKEVETAKSA VKHGAIVFASPWNPPSDMVETFNRNGDTSAKRLKYNKYAAYAQHLNDFVTFMKNNGVNL YAISVQNEPDYAHEWTWWTPQEILRFMRENAGSINARVIAPESFQYLKNLSDPILNDPQ ALANMDILGTHLYGTQVSQFPYPLFKQKGAGKDLWMTEVYYPNSDTNSADRWPEALDVS QHIHNAMVEGDFQAYVWWYIRRSYGPMKEDGTISKRGYNMAHFSKFVRPGYVRIDATKN PNANVYVSAYKGDNKVVIVAINKSNTGVNQNFVLQNGSASNVSRWITSSSSNLQPGTNL TVSGNHFWAHLPAQSVTTFVVNR" CDS complement(36241..36504) /locus_tag="ctg9_20" /transl_table=11 /translation="MDEILKQYIVLYKKMSNMINGPDYPGKEKDIQHQKDQIEVYEKQL QQGFSTDYDYDVFADSVIKCAYGDMTLEDLEAVYYGLTTPFF" CDS complement(36571..38073) /locus_tag="ctg9_21" /transl_table=11 /translation="MKRSISIFITCLLITLLTMGGMLASPASAAGTKTPVAKNGQLSIK GTQLVNRDGKAVQLKGISSHGLQWYGEYVNKDSLKWLRDDWGITVFRAAMYTADGGYID NPSVKNKVKEAVEAAKELGIYVIIDWHILNDGNPNQNKEKAKEFFKEMSSLYGNTPNVI YEIANEPNGDVNWKRDIKPYAEEVISVIRKNDPDNIIIVGTGTWSQDVNDAADDQLKDA NVMYALHFYAGTHGQFLRDKANYALSKGAPIFVTEWGTSDASGNGGVFLDQSREWLKYL DSKTISWVNWNLSDKQESSSALKPGASKTGGWRLSDLSASGTFVRENILGTKDSTKDIP ETPAKDKPTQENGISVQYRAGDGSMNSNQIRPQLQIKNNGNTTVDLKDVTARYWYNAKN KGQNVDCDYAQLGCGNVTYKFVTLHKPKQGADTYLELGFKNGTLAPGASTGNIQLRLHN DDWSNYAQSGDDYSFFKSNTFKTTKKITLYDQGKLIWGTEPN" ORIGIN 1 agaaaacgga agcacactgt acatggtgct ccttgcggct tacaccgcgt tcttgtcacg 61 cttaagcgga caggaagata tcatcgtcgg ctcgccaatc gccggccggc cgcacaagga 121 tcttgagccg atactcggca tgtttgtgaa cacgctggcg cttcggacgc gtccggaggg 181 cgggaagcca ttcgtacagt atttgcagga agtgcgtgag acagcattgg aagcctttga 241 gcaccaggat tacccgttcg aagagcttgt cgataagctt gaattaacac gggatatgag 301 cagaaatccg ctgtttgacg taatgtttgt tcttcaaaac atggatcagg aatcgttgga 361 gctgaatgaa ctttgtctca aacctgcagc acacaatggg catcaaacgt ccaaatttga 421 tttaacccta tatacacagg aacagccccg cggtttgctg acgttccaaa tggagtttag 481 tactgactta tataagaaaa aaacgataga aaagtggctt caatacttca tcaatatgtt 541 actctccatc atcaaagaca acaaagccgc tctcggaaca ataaatatcc tgaatgagga 601 tgagacccat taccttatcc acgagctcaa tcgtacaaaa atagattatc caagaaatga 661 aaccatcagc agactctttg aaatgcaggc agaacaaaca cctaatgctg tagcaattgt 721 cagcgacacc caagtattca cttacgagga cctgaacagc tgggcaaatc aaattgcctc 781 agttctacag ataaagggcg tagggcctga tagtgttgta gccttgttga caggcagaac 841 accagaactc attgcaggaa tgctgggcat tctgaaagcc gggggagcct atctgcctat 901 tgcttctgat ctgcctgttg aacgaatagc ttatatgctg tcagacagcg gggcggcatt 961 actccttcaa tctgaaaaaa cagaaaaaca gctattagac attgaatgtg aacaaatcat 1021 aatcgaagat attcaaaagc aaggaaaaac gaagaacgtt gattcttcag cagggccaca 1081 ttcactcgca tatatcattt atacctctgg atcaaccggt aaaccaaagg gtgtcatgat 1141 tgagcagcga agtgtaattc gtcttgttaa aaacagcaat tatattacat ttacacctga 1201 agaccgcctt ctgatgacat catcaatcgg tttcgacgtt gggtcatttg aaattttcgg 1261 accgctgcta aatggtgccg ctttgcatct gtccgatcaa caaacatttc tcgattccca 1321 tcagcttaag aggtacatag aacatcaagg aatcacaacg atttggctga catcttctct 1381 attcaatcat ttgacagaac aaaatgaaca aacattttca cagctgaaac atttgattat 1441 aggcggagaa gctttgtcgc cgagccacgt caatcgaatc agaaatgtct gccctgaagt 1501 atctatatgg aatggatatg gccctaccga aaatacaact ttttcgacat gccttcacat 1561 tcaaaaaaca tatgaacttt ccattccgat cgggcggccg gttggtaatt ccaccgctta 1621 tatcttaaat caatggggag tgctgcagcc ggtcggagct gtcggtgaac tttgtgtcgg 1681 cggagatggc gtcgccagag gatatttggg ccgtcctgat ttaacgaaag agaaatttgt 1741 cccacatcca tttgcacctg gcgatcgact gtatcgcacg ggtgatctgg cgcgctggct 1801 tcctgatggc acaattgagt acgttggccg tattgatgat caagtaaaag tcagaggcta 1861 tcgggtggag ctgggtgaaa tcgaaacagc atttcgtcaa atagacggag tcaaagaagc 1921 cgcagtgtta gcacgtacag cccagaccgg gagcaaagag ctgtttggct atatcagcgt 1981 aaaagcaggc acgaatgctg aacaagtgcg ttcacttctc gcgtgttcac tgcctaatta 2041 tatgattccg gcgtatatca ttgaaatgga gaatcttccg ctcacatcga acggcaaatt 2101 gaaccggaaa gcactgcctg aaccagattt cgcatctaaa caaacataca tcccgccacg 2161 caacgaactt gaagagcagc tggcattgat ctggcaggag gttctaggca tccagaggat 2221 cggaatagag gattcattct ttgaattggg cggcgattca atcaaagcgc ttcaagtttc 2281 tgcacgtctc gggcgccacg ggttaagctt gcaggtaagt gatttattcc gtcgtccaaa 2341 gataaaagac ttatcaccat ttattcgtaa aacagagaga gtcatagaac aaggacctgt 2401 tcagggagat gttccatgga cgcctattca gaaatggttt ctctcacaag acatagaaga 2461 acgacaccat ttcaatcagt ctgtcatgct tttccatact gaccgtttgt ctgaagacgc 2521 tcttagagca tccttaaaaa agctggcgga gcatcatgat gcgcttcgga tggtttatcg 2581 caacgatgat aggcgatgga ttcaaatcaa ccaaggcatt catgagtcac agctatacag 2641 cttaagaacc tttgatcttt cacagtcaga aagcggctgg gagacgcaaa tcaaacaaga 2701 agttgcagat cttcagcaaa gcatcaattt gcaggaagga ccattgttgc acgccgcttt 2761 gtttaaaaca ctgaccggag attacttgtt ccttgcgatc catcaccttg tcgttgatgg 2821 tgtctcatgg cggattttgc ttgaggattt gtcagccgga tatcaacaag ctgctgcagg 2881 ccagacgatc cagcttccgc ctaaaacgga ttcctatcag gaatacgcaa gacgcataca 2941 ggaatatgcc caaagcagta agctgattcg cgaagaggcg tattggcgaa ctgtagaaga 3001 acagcaagac gcagaactgc cctatgaaat accgcatcaa gtgaacatcg acttcagcaa 3061 aagggactca ttaaactttt cactgactga agcagacacc gccgtcttgc tgcaaaacgt 3121 caatcacgcc tatggcacag atacacaaga tattctgtta accgcagcat ccttggcgat 3181 ttgtgaatgg acaggaggaa gcaagctccg tatcgctatg gaaggacacg ggagagaaca 3241 cattctgcca gagttagata tcagcaggac ggtcggctgg tttacatcca tgtatccggc 3301 cctcataagc tttgaaaatc atagggatga gctcggaacc gcattaaaaa ccgttaaaga 3361 tacactgggc cggataccaa acaaaggggt aggttacggt atgctgaaat accttacaca 3421 ccctgaaaat aaaagcatta cgttttcaaa aacacctgaa atcagcttta actatttggg 3481 ccagttcaac gacatcgaaa gacaggacac cttccgccca tcaagccttg ggagcggaaa 3541 ggatatcact catacatgga agcgtgagca aatcatcgag atgagcgcaa tggcagcaga 3601 caaaaagctc catttcaatc ttagttatcc gccagcccgc tttcacagaa acacaatgga 3661 acagcttatt aacaggattg aacacttttt gctggacatt atgaaacact gcgccggtca 3721 acagaaaaca gaaaagacac tgagcgattt cagcagtcaa tcattaacgg ctgaggactt 3781 ggacagcata tccagcttgg tggaagaatt gtagaaaatc gtgacaggga gacatgaaca 3841 tgacaaaagc gaattcaatt caggatattt atccgctgtc ttacatgcag gaagggatgc 3901 ttttccattc cctcctgcaa aaagattcac aggcgtatgt tgagcaagct tcttttacaa 3961 ttgaaggaaa agtcaacccg cagttttttc aaaacagcat caacgctctt gtagaaagac 4021 atgatatttt cagaacgatt tttatcagcc aaaatgtttc ctctccccag caggttgttc 4081 tgagagaacg aaatgtcatc gtactggaag aaaacattac tcatttaaac gaggcggagc 4141 aatcacagtt tatcgagcaa tggaaagaaa aggaccggga ccaggggttt catttacaaa 4201 aggatgtgct catgcgcatc gctctgattc aaacaggaga gagccagtac tcttgcattt 4261 ggacctttca tcatatcatg atggacggtt ggtgcctcag cattgtgcta aaggagtttc 4321 tgcatattta cgcatcttat gtaaatgcat ccccaataac attggagccg gtccagccat 4381 acggaaagta tatcaaatgg ctgatggagc aagacaaaga gcaggcggtt tcttattggg 4441 accattatct ttccggccac gaacagcaaa ccgtgctccc gaagcagaaa aaaacaaagg 4501 gaaaaagcag gcaggaacac gttacatttt cattctctaa ggaagaaagc agcaggcttt 4561 cagagcttgc tgctagagaa gaagtgacac tcagtacgat ttttcatacc atttggggca 4621 ttctgctaca aaaatataat aataacgatg acgccgtatt cggttctgtc atttcaggaa 4681 gacccgcaga aatcgaaggc attgaacata tggtaggtct tttcattaat acgatgccgg 4741 ttcgggtgca gggggcaaaa acgccttttc ttcaacttat aaaagatatg caaaaagacc 4801 gtcttgccgc tgaagcgtac agctaccatc ctttatatga gattcaatcc cgctcagctg 4861 ttaagcaagg gctgattgat catattctcg tatttgaaaa ctatccggtg cagcaagaga 4921 ttcaaatgct gaacaaacag gaacatgctt ctgatctttt tcagattcat aatttcactg 4981 tcgcagatga aaccaactac agcttttatc ttatggtggc gccaggggaa gaaattcata 5041 tcaaaatgaa ctatgatgcg gagcagcacg atcggtcttt tgtgctctct gtcaaagagc 5101 atcttctgaa tgctgtatca caaatcttaa ataatccgaa ccttccacct gaagaaatcg 5161 atatcacgac agatactgaa aagcggcagc tgattggaga aatcacagat caaacaccag 5221 tttacgaaac catccatgcc atgtttgaaa agcaagcgga aaagacacca gatgctcatg 5281 ctgtaattga tcaagcctgc tcattaacat acagagaact gaataaagcg gctaacagat 5341 tggcacggca tttacgaatg aaaggcgttg tgagacagga acccgttgcg attatgatgg 5401 aacgctcagc ggcgtttatc acaggtgttc ttggtatctt gaaagcaggc ggcgccattg 5461 ttccggttga tccgcattac cctgctgaca gaatccgtta tattctgcat gattgcggct 5521 gttcgcatgt tgtttcacaa gcgcatcttc cctcatcgtt agaagacaat tacattatca 5581 ctcatccaga agatatcgaa agcaaagtag acggcagtaa cataaagtca gtcaacaatg 5641 ctgacgatct gctgtatatg atttatacat caggcacaac aggtaaacca aagggtgttc 5701 aatttgagca tcgaaacatg gctaacttgc tgaagttcga atatactcac tccggcattg 5761 actttgaagc agatgttctg caatttgcga cgccttcctt cgacgtctgc tatcaagaaa 5821 tattttctgc gcttctgaaa ggcggcacac tccacatcgt gccagaagcc ataaaaagag 5881 atgtgcctca gctgtttgca tttataaaca agcatcagac gaatattgtg tttctcccaa 5941 ctgcttttat caaaatgatt ttcagcgagc gagaacttgc gaactcgttt cctgatggcg 6001 tcaaacacct gatcgcagcc ggggaacaat taatgatttc agaccttttc caagatgtgt 6061 tgcgtaaacg cggcatacac ctgcacaatc attacggacc ttcagaaact catgtggtat 6121 ctacgtatac cattcatcct ggagacccta ttcctgagct tccgccaatc ggtaaaccga 6181 taggctgtac tgatctatat attttgaatc atcaaaaaca gcttcagcca tgcggcgtac 6241 caggcgaact ctatatttcc ggcgcaagtg ttgccagagg atatgtcaat cacgataaac 6301 tgacaagcga caaattttca tccgatccat tcaagcctga tgtgatcatg taccggacag 6361 gtgatttggc cagacggctt gaagacggca acatcgaata tatcggacgg gcagacaatc 6421 aagtgaaaat cagaggttat cgaattgagc cgcaagaaat cgaagtcacg ctaatgaatc 6481 atccggacat tagtgaggct gccattctca tctggcaaga tcaaaacggt gaacatgaat 6541 tatgcgctta ctattgcagt gtacaaaagc tgaatgcaat agatttacgc agttatatgg 6601 ctagtgagct cccagaatac atgattccgt cgaaatggat atgggttgac agcatacctc 6661 ttaccccaaa cggaaaagta gatcgcgcag cacttccgga gccagatgct tcaatcagcg 6721 gaaacccata taccgcccct cgaaatctgt tagaggcaaa gctttcgcaa ctatttgaag 6781 atgtgctaaa gaatggacat ataggcatcc aagacaactt ttttgacaat ggcggccact 6841 cgttaaaagc aacagtgctt atgtcacgga tcgcaaagga attccatgtg caagtttcac 6901 ttaaggacat ctttgctcat ccgactgttg aaggattagc tttaattatt cgagaggctg 6961 aacaaaatct gtatgcagca attgaaccag cagaagaaag ggatacatat cctgtatctt 7021 cggcccaaaa acgaatctat gtgcttcaac agcttgatga gggtgtcgcc tataacatgc 7081 ctgcggtctt agaactggaa ggtgcactgg atgtcgccaa actgtctgct gtatgtaaag 7141 aactgatcag ccggcatgag ccgcttcgaa cttcctttgt atccggagct gatgacgagc 7201 cggttcagcg tatccacacc gaagtgccgt ttacgttaag taaagagacc actatcgagg 7261 gatttgtccg tcccttttgt ctcagccagg cgccattatt tagagcaggc cttatagaag 7321 tgtcaaacga gaagcatgta ttgctggtgg atatgcacca tatcatttca gatggcgtat 7381 ccgttcagct cctaatccga gaatttaccg atctttatgc aaaccggcag cttaagccat 7441 tgcggatcca atataaagat tacgccgtat ggcagcagaa atttaaaaag ggagactcgt 7501 accaaaagca ggagacttac tggcagcagc agtttagcgg ggaccttcct atactggagc 7561 ttccaacaga taaacgacgt ccggcagaac ggcaattcat aggcggaaaa gtaacctttc 7621 aattggacaa agagatcacg gcccgcataa agcggctcgc ccataaaaac agaagcacgc 7681 tttatatgac gcttctcgct ttgtattcag cctttttgtc tcggttaagc ggtcaggatg 7741 atatcgtgat tggttcacct atcgccggac ggccccatgc cgaccttgaa gctgttcttg 7801 ggatgttcgt caatacattg gctctccgca cacgcccggc gggtaataag acatttgagg 7861 aatttctgaa agaagtcaga cagacggcac tagaagcgta tgagcatcag gattacccgt 7921 ttgaagagct tgtggacaaa ctcggtgtgc agcgggaaat gagccggaat cctttgtttg 7981 acacaacgct agtccttcag aatatggaac agcaaaagct aaaaatgaat gatgtacagc 8041 ttcagtggaa cgacttggag cacccaatat caaaatttga tatttcccta tacgttacag 8101 agcatgattc cgagcttttc tgtcagtttg aatacagtac agctttgttt gagaaagaaa 8161 ccatccaaag gtgggccagc cttttcacca cgcttgtgga acatacagct gccagtcctg 8221 aaacagaatt ggacaatatt ccaatcttaa caaaagaaga agagcgagat ttcattgaat 8281 catgccatct gtttgaggag acgggctatt caatgaatca aacgctccac tatgcactcg 8341 aacagcaggc agaaaaaacg cctgatcagg cggccgttat cttcgaagat ggagtgatga 8401 cctataaaga attgaacgaa caggctaacc gtatcgcctg ggagctgatc ggacgggggg 8461 taaaacctga aacgactgtt gccattatag gaaagcgttc acctgaaatg ctgcttggca 8521 tttatggcat tcttaaagct ggcggcgctt atctgcccat cgacccggat tatccggaag 8581 aacgaatcag ctttctgctg gaggacagcg gtacaaacat tctcctgctt cagtctgccg 8641 gccttcatgt tccggcattt acaggagaga ttgtctatct caatcagaca aatagcggac 8701 tggcacatcg tttgtccaat ccgaatgtgg atgttctccc gcaatcttta gcctatgtca 8761 tctatacatc cggctctacc gggatgccta agggtgttga aattgaacat cgatcagcgg 8821 tgaatttttt gaattcccta cagtcccgct atcagctaaa gcattcagat atgattatgc 8881 acaaaacatc atattcattc gatgcttcaa tatgggagct gttttggtgg ccttatgccg 8941 gagcttctgt ttatctgctt cctcagggag gcgaaaaaga acctgaagtg atcgcgaagg 9001 ccatagaaga acaaaagatc acagctatgc attttgtgcc ttcaatgctc catgcatttt 9061 tagaacatat aaaatatcgc tctgtaccga ttaagacaaa cagactcaag cgagtgtttt 9121 ctgggggaga acagctgggg acccatcttg tctcccgatt ttacgagttg cttccaaatg 9181 tttcaataac caattcctat gggccaacgg aagcaaccgt agaagctgca ttctttgatt 9241 gtccgccaca agaaaaactt gaacggattc caattggaaa acctgttcat catgtcagat 9301 tatatatcct gaatcagaat cagcggatgc tgcctgttgg atgtatcggt gaactataca 9361 ttgccggagc gggtgttgcc agaggttatt tgaatcggcc ggcattaacg gaggagcgtt 9421 ttcttgaaga cccgttttac ccgggggaac gcatgtacaa aaccggggat gtggcgcgct 9481 ggctccctga cgggaatatt gaattcctcg ggcgcacgga tgatcaggtg aaaatccgcg 9541 gctaccggat tgagccggga gaaattgaag cggcactaag aagcatagaa ggtgtaagag 9601 aggcggccgt taccgtacgg acagacagcg gtgagccgga attatgcgct tatatagaag 9661 ggctccaaag aaacgaagtc cgagcgcagc ttgagagact gttgccgggc tacatggtcc 9721 cagcctatat gatagaaatg aaacagtggc cggttacgcc aagcggaaag ctcgaccgaa 9781 acgccctgcc agctcctggc ggagcggcag atgcggagac ctacacagcg ccgagaaacg 9841 tgactgagat gaagctttct cagctgtggg aggacgtgct gaaaaatggc cctgtcggga 9901 ttcacgacaa cttttttgac cgcgggggac attccttaaa agcaacggcg cttgtctcac 9961 ggatcaccaa agaattcgat gtacaggtgc cgctaaaaga tgtgtttgcc catccaacag 10021 tagaagggct ggctgccgtt atccgtgaag gaacggacag tccatatgaa gcgattaagc 10081 ccgctgaaaa acaggaaacc tatccggttt cctctgccca aaagcggatt tatgtccttc 10141 agcagctgga agacggaggg acaggctaca atatgccggc tgtgttagag ctcgaaggga 10201 agctcaaccc tgaaaggatg gacagagctt tcaaagagct gatcaagcgc cacgagtcgc 10261 ttcgtacctc cttcgaacag gacgcaggag gcgatccggt gcagcgcatc catgacgagg 10321 tgccgtttac gttacagact acagttctcg gcgaacgaac cgaacaggag gccgcagccg 10381 catttatcaa accgtttgat ctcagccaag cgccgctgtt ccgtgcccaa atcgtaaagg 10441 tatcagatga gcggcacctg ttgctggttg atatgcatca catcatttca gacggtgttt 10501 ccgtcaacat tctgattcgg gaattcggcg agctgtacaa taatcggaat cttcctgcgc 10561 tgcgcattca atataaagac tacgccgtat ggcaagaagg attcaaaaca agagacgcgt 10621 acaaaacgca gggggcgtac tggctgaagc agctcgaggg cgagctgcct gtgctggatc 10681 ttccggctga tcatgtccgc ccgccggtgc gaagcttcgc tggtgacaag gtctcattta 10741 cgctggatca agaggttgca tcagaccttc acaagctggc acgagaaaac ggaagcacac 10801 tgtacatggt gctccttgcg gcttacaccg cgttcttgtc acgcttaagc ggacaggaag 10861 atatcatcgt cggctcgcca attgccggcc ggccgcacaa ggatcttgag ccgatactcg 10921 gcatgtttgt gaacacgctg gcgcttcgga cgcgcccgga gggcgggaag ccattcgtac 10981 agtatttgca ggaagtgcgt gagacagcat tggaagcctt tgagcaccaa gattacccgt 11041 tcgaagagct tgttgataag cttgaattga cacgagatat gagccggaac ccagtgtttg 11101 acgcgatgtt agttgttcaa aataatgatt acgagcgatt gcatcttcat gatttgcaaa 11161 tgaagccggc acaagtttct catctcgttt ctaaattcga tttgacacta caggcatctg 11221 agggcgacgg aaacattcat ttcctttttg aatattcaac cgcattgttc gagaaaacca 11281 ctattgaacg ctgggcatcg catttaacaa atgtacttag catcatcggc aaaaatccgg 11341 aggtgacact caaccatatc gacatcctga cccaagaaga gcggcaccag ctgcttaatg 11401 agtttaacac caggcaagcg aatcaatacg gagttcaaac aatcagtcaa ttgtttgagc 11461 agcaagctgc acgaacacca aaagctactg cacttgtcag cggagacaaa acactgacgt 11521 atcaagagtt ggacgagtgg tccaatggaa tcgcacgtgc attgcgcaac agaggtgtta 11581 agccggacac accagtaggc atcatgatgc atcgttcgtt cagtatgata gcatccatac 11641 ttggtgtgtg gaaagccgga ggctgttacg ttcccattga tcctgaatac ccgaaagaac 11701 ggaaacgcta tatcctcagc gacagcggaa cgaaactgct gatgacaata aatgaagcgg 11761 atctgggagt acttgctgac tttgaaggag agatcttgac gatagaaagc gtagaggaag 11821 acgacaaatc gccgctgccg caaatgtcgt ctgcccatca tttggcttat atcatttata 11881 cttcaggaac gacgggccgt ccaaaagggg taatggtcga gcataaaggg attgctaaca 11941 ctcttcagtg gcggcgaaac gcttatgcat tcaacgagac agataccatt ctgcagctct 12001 tttctttctc atttgacggc tttataacta gtatgtttac accgcttttg tcaggtgcaa 12061 aagccgtttt gcttcatgaa gaggaagcga aggatattct ggccattaag catcagctgt 12121 ctcgtcaacg gattacacat atgattattg tgcctgtttt atatcgagcg cttttggacg 12181 tagtgcagcc ggaagatgta aagacgctta gagtcgtcac actggcggga gaagcggctg 12241 accgcgaatt gatcgcccgc agcttagcta tatgtccgca taccgaactc gccaacgaat 12301 atggaccgac agaaaacagc gtggcgacta ccgtcatgag acatatggaa aagcaggcat 12361 acgtaagcat cggccagccg attgacggaa ctcaagtgct gattttaaat agcaatcatc 12421 agcttcagcc aatcggtgtt gcgggagagc tttgtatagc aggaacaggg cttgcaagag 12481 ggtacgttaa tcttccagaa ctgacagaga gagcattcac gcagaatcca tttaaacccg 12541 aagcacgaat gtaccgaaca ggagacgccg ccagatggat ggccgacggt acactcgaat 12601 atctcggaag aatcgatgat caagtcaaaa tcagaggata ccgtgtagaa acgaaagaaa 12661 ttgaatcggt catccggtgt ataaagggtg taaaagacgc cgcagtagtt gctcatgtaa 12721 cagcgtcagg acaaaccgaa ttaagcgctt atgtggtgac aaaaccaggg ttgagcacaa 12781 atgctgtacg ctcagaatta caaaacaagc tgccggtgtt tatgcaccct gcgtttattg 12841 aaaaactgga ctcacttcca ttgtcaccaa acggcaagct ggatcgcgga gcacttccaa 12901 aacctgtata caaccacgaa ggtgaacgtc cattcctccc gccatccagc aaaatggaac 12961 aaatactggc agatatatgg aaagaagtac tgggggcaga aaagatcgga acagctgatt 13021 cgttctttga acttggcgga gattcaatca aagcgttaca ggtatctgcg cggcttcacc 13081 ggataggcaa gcaaatggca gtgaaagatt tgtttagcca tccgaccatt caagaattgg 13141 cagcttatat ccgtgattca gatacaagtt ccagccaagc tgcggttgag ggagacgtac 13201 aatggtcgcc tgttcaaaaa tggtttcttt ctcaagatat aaaagaaaaa caccatttta 13261 atcagtccgt aatgctgcat cgaagcacct ctgtacaaga agacgcactg cgaaaaacgt 13321 taaaagcaat aacgtgtcat catgatgcgc tgcgaatggt gtttacacag aatgaacaag 13381 gaaagtggga tcaatataat cggccgctca gtcattcgga cgacgcgttg tacggccttc 13441 agatgattga tttgtcagct ccggacggca ctgatggaaa tagagcgtat gagcctatta 13501 tcaaacgcca tgtacttgat attcagcaga aaatggattt gaagaatggt ccgctgctgc 13561 aagccggtct tttccacaca attgacggtg atttcttatt tttatcggct catcacctcg 13621 tcgttgacgg catctcatgg cgggttctgc ttgaagattt ggctttaggg tatcgccaag 13681 ctgcaggcgg cgggaaagag attcagctgc ctcctaaaac aagctcattt aaagcgtaca 13741 cgaaaaagct ctctgactac gctgaaagcc agcagctcat gaaacagctc aagtattggc 13801 gcgaggccga agagtatcaa acagaggcat tgccttttga tcacattgat ggaactagag 13861 cacacgaggg acaacggtcc acgatttcgt ttaccttaaa cgagaaagag acagcagcac 13921 tcttaaaaga tgccaacagc gcatataaca ctgatacgca ggacatgctg ctcgcttctg 13981 tcattcttgc gctgcgccat tggaccaatc aatccgcctt caaactatca ttagagggcc 14041 acgggcgaga ggatgtatta aaaggaatag atgtgagccg gacgattgga tggtttaccg 14101 ccatttatcc gttattgatt aaactgaacg cagacttgcc agattcggaa gaaagcatgg 14161 ttcatgtgct aaaaacaaca aaagatacac tgagacgtgt acctgacaaa ggattcggct 14221 acggtgtcat caaatatttg actccgcctg gcaaaaaaga catcaatttc acaggtgcac 14281 cagaaatcag ctttaattat cttggtcaat ttgaaagcgg ccgcacagct gaagtacctg 14341 aggaggacgc cttctcattc tctccgctgg gtgccggagg tgatatcagc acaacatgga 14401 accgtgaaca gtcgctggat atcagcgcaa tcgctgcaga aggaaaattg actgtcaata 14461 tgacttatga caatgcccgc tttcagcgca aaaccatcga acagcttagc gaaacatgcc 14521 gtcaattttt attacagctg atcgaacact gccagaacaa aagcgaaaca gaaaagacga 14581 tcagtgattt tgatgatcaa gaactgaccg aggacgccct gcaagagatc gctgatatgc 14641 tcagttttca ctaatgaatc cgtgaagaaa ggtgcagaca ctatgaatac cattaaaaaa 14701 atcaagaaca tttatcctct gagtcatatg caggaaggga tgctgtttca ttccttcctc 14761 cgtaaagagg agggggcgta tgttgagcag tcgctcttca ccattaaagg aagcctcagc 14821 tatgactggt tccagcgcag cattcaagcc attatcgacc gccatgatat tttcagaacc 14881 gtgtttttgc cgcacgtccc gcatttgtcg ggacctcggc aagtcgtgat gacagaacgt 14941 gaattccatt tgaacagcga agacatttct catctgccga caaacgacca gaatgagtat 15001 attgaacgct ttaaagagaa ggacaagcaa aaaggctttg atctgcaaaa agacatgctg 15061 atgcggattt ctctattcaa aacagctaaa gatgagcatg tctgtatctg gagtcaccat 15121 cacattttaa tggacggatg gtgcctaggt atcgttatgc aggaatttat gcaaatttat 15181 caatcgattc atgcaggaaa accgctttca ttagaccctg tccgtccgta cagcacctat 15241 atttcatggc tgacaaaccg agacaaagaa aaagcagcgg cctactggga tacctattta 15301 aaaaactaca gcgctccatc acctctgcct cgtgtgtctg ataaagaaac aaaagaaggt 15361 tatcaccgtg aagatttgat attttcatta aataaaccac tgacagacaa gctgaaagag 15421 actgccaaac aacacggcgt cacgctcgct acccttattc aggcagtctg gggtgtgatg 15481 ctgcagcaat ataaccgcac agacgacgtt gtgtttggcg cagttgtatc aggaagaccg 15541 tcagaaatcc caggcgtgga gcaaatgata gggttgttta tcaataccat accgattcga 15601 attaaaacac accaagacga aacgtttcac gagctgctca tacgctgcca gaaagaaatg 15661 ctggaagctg agccgtttac ctgccagcct ttatttgata ttcaggcaaa caccgcatta 15721 aaacaggaac tgattgatca cattatcgtc tttgaaaact atccgttaca gcagaaaatc 15781 gccgattccg ctgatcaaac cgattcaccg ctgcaaatcg atcaagttca agtatccgag 15841 caatcaggat ataactttaa tcttgtcgtt gctcctggcg aagagcttgt catcaagttc 15901 agctataatg cattcgttta cgatgctgcc tggatcagct gtatcaagag gcaatttacg 15961 caagcgctta gcacagctgc acagcaccct catatgccaa ttgctgattt ttcttttctt 16021 gatgcaacag aaaaagagca gattgtcaca cagttcaaca atacaaaaac ggagtatcca 16081 aagaatcata caattatcga tttatttcgc gaacaagcag aaaagacgcc agaccatacc 16141 gcacttgtgt atggcaatat gtctatttcg tataaagagc ttgataaacg ctctaatgcg 16201 ctcgccagag agttaattca aaagggattt cggcaaaacg agacagccgg aatattggct 16261 gcacattctc ccgaattcat gatcagtgtg cttgccgtat taaaagcagg gggagcatac 16321 ctcccgcttg atgcggagct tccgcctgaa cgagtcagct ttatgcttga ggaaacgcaa 16381 gcaaaaatgt tgattgttca aaaggggctg gagcaaaatg ctgcgttctc aggaacatgt 16441 atgattgcag atgcgcaggc attgatggaa gagaatcatt ttcctatcaa cagcagctcc 16501 agtccagatg atcttgcata tatcatgtat acctcaggat caacaggccg gccgaaaggg 16561 gtcatgatca cgaatcgcaa tgtcgtgtcc cttgtcagca acagcaatta cacatctgcg 16621 tccggtgatg accggtttat tatgactgga tctatcagct ttgacgccgt cacctttgaa 16681 atgttcgggg cacttttaaa tggcgcaagc cttcatatca ttgataaatc gacaatgctg 16741 acacctgatc ggtttggagc gtatttgctt gaaaatgaca tcacagtgct atttttaacg 16801 acagctcttt ttaatcagct ggcacaggta cgagctgaca tgtttcgcgg actccatacg 16861 ttatatgtcg gaggagaagc actctctcct gctctgatga atgctgtcag acacgcctgt 16921 ccagatctcg cgcttcataa tatttacggg cctacggaaa acacgacttt ttcaaccttt 16981 tttgaaataa agagagacta tgcggggccg attccgattg gaaaaccaat cagcaatagc 17041 accacttaca tcttagatac aaaaggacgt cttttgccaa taggcgttcc cggcgagctt 17101 tgtgttggcg gtgatggtgt cgctaaaggc tatttgaaca gagatgacct gacaaatgct 17161 cttttttctc ctcatccttt cttgcctgga gaaagaatat accgtaccgg tgatttggcg 17221 cgctggctgc ctgatggaaa cttagaatac atcagcagaa ttgacaggca aatgaaaatc 17281 cgcggaaaac gaattgagcc tgccgaaata gaagcgcgcc tgttagaaat ggaaggcgtt 17341 caagaagcag cagtgacatt gagagaaaaa gatggagagg cgcagctgta cactcattac 17401 gtcggtgatc acaaaaaaac agatacggat tttcgcgccg atttggcgcg tgtgcttcca 17461 gactatatga tcccgcagca ctgggtgcgt gtggagcgga tgccgcttac cggaaacgga 17521 aaaatagacc gcagcgcgct gcctattcca gaaaataagc ctgccaaacg acaggacatc 17581 atattgccaa gaaacttggt tgaagaagaa ttagcgaaca tttggaagca agttctcggt 17641 gttaacacaa tcagtattga tgatgacttc tttgctattg gcggacattc actaaaagca 17701 ctgcaagtca tacatacact aaaacatcag cagaacattg acataccgat tgatttcttg 17761 ttcgaacatc cgacaattgc tcagcttgcc gagaaacttt attctaaaca gctgacagcg 17821 gcaaatgaac agcatgtgat caaactgaac cagcacggcg cgcaaaatct tttctgcttc 17881 ccgccgatat caggatttgg catttatttt aaagaccttg ctttattact gaatgagaag 17941 gcagccctat acgggtttca ctttattgaa caagacaccc gcattgaaca atatgttaat 18001 tgcatgacgg acatacagcc tgagggccca tacgttttat taggctactc tgctggcgga 18061 aacctggctt ttgaagtggc acaggctatg gagcgcaaag gattggaagt cagcgacttc 18121 attatcgtgg acgcttatct aaaagaacag cctttgccta tcgataccgg gaatgacgaa 18181 tctgcagcat atctgcctga agcagtcaga gaaaaggtga tgaagaaaaa aagaaactat 18241 caggaatatt gggcacaatt gctgaatgaa ggccacatca aagcaagcat tcatttcatc 18301 gaagctggaa tccaccccga aaccagcggg catacaggct taacgaaatg ggaaggcgcc 18361 tgcggaaact atagtgagta cacgggtttt ggcgctcata aagacatgct ggaaggaaca 18421 tatgctgaaa agaatgctga catcatcctc gacattttag aaaagatcac ttcaaatcaa 18481 gtaatactgc acaaacgata aagcggatag cggacagagg ccattctctg tccgtctttc 18541 tttttgtatc aagaatggat aagggacact tgggaatgat aacatcatcc tttttcttgg 18601 aggcttctca atggaccgtc tttcttttct aacttttatc atgctgattc tagccagtta 18661 caggctgaca catttgattg tatttgacaa aatcacagaa tttatccgaa aaccttttat 18721 gaaaaagaaa aggattgttg atcaaaacgg gcatgtagat gaaaaaagcg tgccggcttc 18781 taactttgga tacatgctca attgctactg gtgtgccggt gtttggtgtg ccatcttgat 18841 cggacttggc tatctttttt tgcctcgtat tgcaataccg ctgatcttta ttttagccat 18901 tgccggagca caagcgatcc ttgaaacggc tgtcggtgtc ggcgtaaaac ttattgacgt 18961 gttaaaaagt ttgcaaacca tgatgaatga taaaaagtcc taaaagcggc ccacaacatg 19021 ctttaggact tttttcgttt atttagtgag atagacattc tgttaatcac ccttttatag 19081 cccgggaata ccgtaatagc gagtgaaagt gatgtaatgg gggagaagaa acagaatgaa 19141 ggtttgccaa aagtcgattg tccgtttcct tgtcagcttg atcatcggaa cgtttgtcat 19201 ttccgttccg tttatggcca atgcgcagtc tgacagagag ctgagagccg tatggattgc 19261 ttccgtatta aatattgatt ggccgtccaa aaaagggtta tctgtgaaag agcaaaaaca 19321 ggagtatatc aaactgctgg acgatgtgca aaaaatggga atgaatgccg ttatcgttca 19381 gattaaaccg atggctgatg ccttttatcc gtcagcttac gggccttggt cggaatactt 19441 aaccggtgtc caagggaagg acccgggcta tgatcctctt gcatttataa ttaaagaaac 19501 ccataaacga aatttggaat ttcacgcgtg gtttaatcct taccgtatta caatgaatca 19561 tacagatctt aataaattgt ctgaggatca cccggcaaga aaacatccag attgggttgc 19621 cgcctatgga aaccagctgt attatcatcc aggcattcca gaagcgagag attttatcgt 19681 caaaggcatt gaagaagtcg taaaacatta tgatatcgat gctgttcata tggatgatta 19741 tttttaccct tataaaatag cgggacagga atttcctgat caagcacagt acgaacaata 19801 cggaaaaggc gctttttcta atatcgatga ctggcggcgg gacaatgtga accagcttgt 19861 caaacaaatc aaccaaacaa ttaaagctgc aaaaccgtat gtcaaattcg gcatcagtcc 19921 ctttggagta tggagaaacg ccgcagatga cccgaccgga tcgaatacaa aagcaggcgt 19981 cagaaattat gacgatctat atgcagacac aaggcattgg atccaagaag gcgacatcga 20041 ttatattgct ccgcaaattt attggagtat cggctttaac gcagcggcgt acgacgtgct 20101 ggctgattgg tggagcaatg aagtcaaaaa taggcctgtt cacttatata ttggccaggc 20161 agcatataaa atcaataaca attttgatcc gccttggtcc gaccctgagg aatatgtgcg 20221 gcaaatcact ttgaaccgcc agcttgaact ggtgaaagga agcatgcatt tcagcctcaa 20281 ggacctcaac aaaaatccgc ttagcatcaa agacaggctc agcaccgatc tttacagcaa 20341 gccggcactg gttccgcaaa tgccttggct tgacaatact gccccaaaaa aaccgaagct 20401 tacgaaagtc accgaagaca aaaacggcaa tcttctgcag attaaagatc acccatcaaa 20461 tctaaaaacg aaagaaacag cctattatgc gatatacaga gccgaaggga aaaagcagag 20521 aacattgctg gcaacgcaaa gaaaaacaca tgagcagcaa accttcttag ataacacggc 20581 agatcctaac aagaaatata cgtattatgt cacttcagca gaccggcttc ataacgaaag 20641 caaagcttcc aaacgaacaa caaaataaga aatgagaagg acggctttct aagtcgtctt 20701 ttttagtgat tttggagaca ggaaacgatg gtaaaccgct gtattttaaa aaaaaacaaa 20761 tgtgagattc acatgaatat ggaggcggtg tttcgacatt ttccattatt ggaatctgag 20821 aaactagtgc taaataaaat cgaagagaaa cacgtacagg acgtgtttta cgtgttcatt 20881 tctagtctgg ttaggtgcca cattattttt tgtgctgttc gaagatgctg tgttgactga 20941 tccggctgaa gaagcctttt tgacgaactt tcttctcttg gaagcgggca ccgctcttgt 21001 tttatgcctt gtgttctttc tctatcaaaa actcgatcaa tcacagttcg cggtgatcaa 21061 gctaggtata tggggatcag cggtcggttt attgattgat acgatttccc tttggaatca 21121 tcccctcatc ctcccggctt tatcaaaggg ccaagttatt gcgtttgcga tatggatggt 21181 atgcgcctac tgcatgtatt tgctcattcc gctgaaatta tcacataaaa aatgattcag 21241 ttttaatttt cagacttttc ttgtcaggga atgattatag aactcgccta ataggatgtt 21301 acaaagatgt gaaggaggaa acgatgtgaa ttttgagctg acaaaagaac aacaaatggt 21361 gcgtgaaatg gtaaaagatt ttgcgaaaaa agaaattgct cctcacgctg aacatgtaga 21421 tcaaacaggc gagttcccaa tgcaaacatt tgaaaaaatg ggtgaactcg gtctgatggg 21481 tattccattt cctgaagaat acggcggatc tggcggtgat acgatttcat atgccttagc 21541 ggttgaagaa gtcggcaaag cctgcggcag tactggatta agctatgctg cagcggtctc 21601 gctaggcgca agccctcttt actacttcgg aacagaagag caaaaacaga cgcatttgac 21661 gccgctggct tcaggcacag cactcggatc attcggcctg acggagccaa atgccggctc 21721 agatgcagga ggcactcaaa caaaagcgat ttcaaatggt gacgagtatg taatcaacgg 21781 cgaaaagtgc tggatcacta atgcaagcta cgcacgcaca gttattgtaa ccgccgtaac 21841 aggcaaaaac aaagacggaa aaaacatcat ctccgcatta atcgtgccaa ctgatacacc 21901 aggacttacg attacgagcc cgtacgataa aatgggcgtc cgcggttcga atacagcgga 21961 aatcttgctt gaagatgtaa gagtgcctgc ggccaactta cttggcgatc caacaaaagg 22021 gtttaaacag tttctatata cgctggacgg agggcgaatc tccatcgctg ctcttgcagt 22081 cggcattgcc caagcagccc ttgacgcatc attggcatat gcgaaagaac gaaagcagtt 22141 tggacagccg atttcttcct ttcaagcgat tcaatttaag cttgctgaca tggcgatgga 22201 aattgatctg gcacggcaaa tggtgttaaa agccgcctgg ctgaaagacc ataaccgccc 22261 gttcaccaaa gaagcggcgt acgccaagct attcgcatct gaaatggcga caagagcttg 22321 caatcaagcc attcaaatcc atggaggttc aggctatatg aaagagtatg gggtggaacg 22381 gatgctgcgg gacgcaaaat taatggaaat cggtgaaggc acatctgaaa ttcagcgtct 22441 cgtgatcgcc agacagcttt taaaataaaa atgtaaacgc tttcccatca ttaagaaagg 22501 aggaacaatg aatggctgaa ctcatccatt ccacaatcgg caggctgctg gaacaaacag 22561 ctgatgcgta tcccgatcga gatgctgttg tgtatccaga ccgaaatatc cgctatacgt 22621 acgctcaatt tgacagtctg tgccgtcaaa ccgctaaagg tcttatgcgg atggggattg 22681 gaaaaggaga ccacgtcgcc atatgggctt ctaatatccc tgaatggctt gccgtccagt 22741 tcgcaactgc gaagatcgga gccgtgctcg tgaccgtcaa taccaattat caagcacacg 22801 agcttgatta cttgttaaag caatcggatg ccgcggcgct tattatcatg gattcataca 22861 ggggcacttc ttatccagac atcgtgaaca gtttaattcc agaactgcaa gaagcaaagc 22921 ccggccaact gaaatctgaa cgctatccct ttttaaaaac gctgctctat attggcaata 22981 aacggttgcc tggcatgtat cattgggacg atacagagat attggcgaaa acagtgacag 23041 atgctgagct tgaagagaga atgaacagcc tggataaaga caatgtgatt aatatgcaat 23101 acacatcagg aacgacaggg tttccaaaag gcgtgatgct gacccatttc aatgtcatca 23161 ataacgctgc caatatcgct gaatgtatgg ctttaacctc tcaagaccgc atgtgcatcc 23221 ctgttccgtt ttttcactgc tttggatgcg tccttggggt tttggcatgt gtatccgtcg 23281 gggcagccat gatacccgtg caagaatttg atcccgttac cgtccttaaa acggtagaaa 23341 aagagaaatg cacagcgctc catggtgtgc ctaccatgtt tatcgccgag ctgcatcatc 23401 cggattttga tgcatatgat ctatcgacgc tccgaacagg aatcatggcc ggctctccct 23461 gtccaagtga agtgatgaaa gctgtgattg aaaggatggg catgaaagac attacgatcg 23521 cctatggaca aaccgaagcc tcgccagtca ttacacaaac gagagcaaat gattccttca 23581 taagaagagt cgaaacaacc ggacgcgccc tgccacatac tgaggtgaaa attgtagaac 23641 ccgggacatg tcaagaagtt caaagaggcg tgcagggaga actgtgcacc cgcggctatc 23701 acgtcatgaa aggctattat aaagacaaag aagcgaccag aaaagcaatc aatcatgacg 23761 gatggctgtt taccggagat cttgctgtca tggatgaaga cgggtactgc cgcatcaccg 23821 gaagattaaa agatatgctc atcagaggcg gcgagaacat ttatccgcgg gaaattgaag 23881 aatttttata ccggcatccc gctgttttag atgtacaggt cgttggtgtg cctgacgcca 23941 aattcgggga ggaagctgca gcctggatta aactgaaaga cggtaaaagc gtttcacctg 24001 atgagcttaa agcctattgc aaagggaaaa tcgcccgcca caaaattccg cgttatgtta 24061 tttttacgga tgactatccg atgacggcct caggcaaaat tcaaaaatat aaactgcgag 24121 aaaaaacgat tgaaatgttc aacttatcat caagtcaatg aggtgaaatc atgtttacaa 24181 aagtactgat cgccaaccgc ggagaaattg caatgagaat tatccgaaca tgcagccgtc 24241 tcggcattaa aacggtcgct gtttattcag aagcagacaa ggacgcgccc catacaaaag 24301 ccgctacaga ggcatatttg atcggggaat cgagagtcag tgaaagttat ttaaatatag 24361 agagaatcat aaagacggcg aaaaaagcaa atgccgacgc gatccacccg ggatatggat 24421 tgttatcaga aaacagccgg ttcgctgaac gctgcaagca agaaaacatc gtgtttatcg 24481 gaccttcccc tgatatcatc gaaaagatgg gcagcaaaat tgaagcgcga aaagcaatgg 24541 aggctgcagg tgtccctgtg gtgccgggcg tttctgaatc cctcggagat atagaggcag 24601 cctgccgcac cgcaagtcaa atcggctatc ctgtcatgct gaaagcttca gcgggcggag 24661 gaggcatcgg aatgcagcgt gttgaaaatg aagaagcatt aaaaaaagcg tacgagggaa 24721 acaaaaagcg cgcagcagat tttttcggtg acgggtcgat gtatatagaa aaagttattg 24781 aacatgcgcg tcacatcgag gttcagcttt tggccgatca acacggccat acagtacatc 24841 tgtttgaacg tgattgctct gttcagaggc gccaccaaaa agtcattgaa gaagcaccgt 24901 ctccatttgt agacgatgaa ctaagaatga agatcgggca aacagcggta aaagcagcga 24961 aggcaatcgg ctatacgaac gcaggcacca tcgaatttat agttgaccag aagcaaaatt 25021 tttatttcct cgaaatgaat acgagactgc aagttgaaca ccccgtgact gaagaaataa 25081 caggcctgga cttagttgag cagcagctgc ggattgctgc gggccataca ctcacattct 25141 cccaaaaaga catccaacgg aacgggcatg cgatagaggt gcgaatatac gcggaagatc 25201 ccaagacctt cttcccgtca ccaggtacga tcactgcgtt ttcacttcct gaccaaaaag 25261 gagtcagaca cgaatgtgcg gtagcaaaag acagcaccgt tacccctttt tatgacccga 25321 tgatcgctaa gatgattgtc aaaggccaaa ccagaacaga agcaattgaa aaactagaga 25381 cagcgcttcg cgactatcgt gtagagggaa tcaaaacaaa ccttccgctt ctcatacagg 25441 ctgcggcaac aaaggcattt aaagaagggg atgtcacgac tgactttttg aaacagcacc 25501 tataaaggag gcagttgtca tgacggttag catacaaatg gcaggaaacc tgtggaaagt 25561 ccacgtcaaa gccggcgacc aaatcgaaaa gggccaggag gtagccattt tggaatcgat 25621 gaaaatggaa atcccgatcg ttgcagatag aagcggaatc gtaaaagaag tcaaaaaaaa 25681 tgaaggcgac tttgtaaatg aaggagacgt actgctcgaa ctgagcaatt ccactcaata 25741 atttggagga agaccatgtc atatcctaaa aaagtgacaa tcaaagaagt cggcccgcgt 25801 gacggcttac aaaacgagcc cgtatggatc gcaacagagg ataaaataac ctggatcaac 25861 cagctttccc ggacagggct ttcgtatatt gaaatcacat ccttcgttca cccgaaatgg 25921 attccggcgc ttcgagatgc tatcgacgta gcaaaaggca tcgaccgtga aaaaggggta 25981 acgtacgcgg cacttgtccc gaatcaaaga ggactggaga atgcgcttga aggaggcatt 26041 aacgaagctt gcgtttttat gtccgccagc gagacgcaca acagaaaaaa catcaataaa 26101 tccacttctg aatcccttca tatactcaaa caagtaaaca acgacgcaaa aaaagcaaac 26161 ctcacaacaa gagcctacct ctcgactgtt ttcggctgtc cgtacgaaaa agatgtcccc 26221 attgaacaag tcattcgcct ttcagaagct ctatttgaat tcgggatttc tgaactgtcg 26281 cttggagata cgattggagc ggctaatccc gcccaagtgg aaactgtact tgaagctctt 26341 ttggcacgat tcccggctaa tcaaattgcc ctgcattttc atgatacgag aggaaccgct 26401 ctggccaaca tggtcacagc actccaaatg ggcatcacgg tgttcgatgg ctcggcaggc 26461 gggcttgggg gatgcccata tgcgccaggt tcatcaggaa acgccgcaac tgaggatatc 26521 gtgtacatgc ttgaacagat ggatatcaaa acaaatgtaa agctagaaaa actgctatct 26581 gcggccaaat ggatagaaga aaaaatgggc aaaccgctgc cgagcagaaa tttacaggtg 26641 tttaaatcat cttgataaaa gggaggacgc atacaatggg aaactctatt ctttttactg 26701 ttaaaaatga acatatggcg ttgatcacct taaacaggcc tcaggcagca aatgctcttt 26761 cagcggaaat gcttagaaac ctgcaaatga ttcttcagga aattgaattc aactcaaaca 26821 tccgctgtgt catcctcaca ggcaccggtg aaaaagcgtt ttgtgcaggg gcagacctga 26881 aggaacggat aaaactgaaa gaagatcagg ttctggaaag tgtatctctc attcaaagaa 26941 cggcggcttt acttgatgcc ttgccgcagc cggtcatagc tgcgataaat ggaagcgcat 27001 taggcggcgg actagaattg gcattggcat gcgaccttcg aatcgcaact gaatcagctg 27061 tgctgggact tccggaaaca gggttagcta ttatcccggg cgctggaggg acccaaaggc 27121 tgccccggct gattggcaga ggaaaagcaa aagaattcat ttatacaggc agacgcgtga 27181 ccgcacacga agcaaaagaa atcggccttg tagagcatgt cacggctcct tgtgacctta 27241 tgccaaaagc agaggaactg gccgcagcca tttctgccaa cggaccgatc gctgtccgtc 27301 aggctaaatt tgcaatcaat aaaggattgg agacagatct cgctacaggc cttgcgattg 27361 aacaaaaagc gtatgaacaa accatcccga caaaagacag gagagaaggg cttcaggcct 27421 ttcaagaaaa aagacgggcc gtatacaagg gaatataaaa gggaggcaat gctgatggat 27481 tatgaaaagg aacgaacaga acgggctgaa cggattcgaa aaggcggagc ggaaaagtat 27541 catcaaagca atcgggaaaa aggcaagctc tttgtcagag agcggctttc ccttctcttt 27601 gacgatgaca ttgagctaga agacgctttt tttgcggaat gtatgtcaga cgggcttccc 27661 gctgacggag ttgtaaccgg tatcggcaaa atcggcggcc aaactgtttg cgtcatggcg 27721 aatgattcaa cagtgaaagc ggggtcatgg ggagctaaaa cagttgaaaa aatcatcaga 27781 attcaagaaa ccgccgaaaa attaaactgt ccgctcattt atttagtcga ttcggcaggc 27841 gcccgaatta ccgaccaaat caatgtcttt ccagggagac gcggtgcagg aagaattttt 27901 tacaatcaag tcaaattatc gggacgcatt ccgcaaatct gtctgctttt cggaccatct 27961 gcggcaggtg gcgcttatat tccggccttc tgtgatatcg tcgttatggt agacggtaac 28021 gcctccatgt atttaggctc gccaaggatg gcggaaatgg ttattggaga aaaagtgtct 28081 cttgaagaaa tgggtggcgc ccgtatgcat tgctcaattt ccggctgcgg agatattctt 28141 gcagaaactg aagaagaagc catacagctg gcgcgggctt atttgtctta ctttccggca 28201 aattttcaag aaaaagcgcc cattcatgag aaacgcccgc caaaacactt cgacaccccg 28261 cttgccgatg tcattccgca aaatcaaaac gcaccttttg atatgcatga gctgattgag 28321 cgggtcatag atgaagactc attttttgag atcaaagcct tatttgcacc ggaattattg 28381 acgggcctcg cacgaatcca cggacagcct gtcggcattg ttgcaaacca gccgaaggta 28441 aaaggaggcg tcttattcca cgattcagct gacaaagcgg ctaagttcat taccttatgt 28501 gacgcttttc atatcccatt gctgttctta gccgatatcc ccggttttat gattggcaca 28561 aaagtagaac aggctgggat tatcagacac ggagcgaaaa tgatttctgc gatgtcggag 28621 gcaactgttc caaaactctc tgtcattgtc cgaaaagctt acggggcggg gttgtatgca 28681 atggcagggc cggcatttga accggattgc tgtctagcgc tcccaaccgc ccaaatcgcc 28741 gtcatgggcc ctgaggcagc tgtaaacgct gtctacgcta aaaaaatcgc cgagctgcca 28801 gaagaagaga gagccgcatt tatcagcagc aaacgggagg aatacaaaga ggacatcaat 28861 atctaccgtc tggcttcaga aatgatcatt gatgctgtta tcccagccaa ttcgctgcgt 28921 gatgagctgg ccaaacggct caaggcatac atgacaaagg aaatgacatt taccaatcga 28981 aagcatccgg tttatccggt gtaaaagcaa gaacttagga gcgcaaaaaa agcgctcctt 29041 tatatattta caataacaac attatgtcaa ctaattacca ttgcataaaa cggttggttt 29101 tttagaatag taaataaagg ctgccgcacc tctagcggca attgtcagtt tatcataaaa 29161 aggggcctac attatgtatc atttatattc acataacgac ttggacggag tagggtgcgg 29221 aatcgtagca aaattggcgt tcggaaaaga cgtagaggtc cggtataact ctgttaacgg 29281 cttaaacgca caggtgcagt actttttaga aaaagcgaag gagagcaaca gacaggacgc 29341 gttattcatc accgatctcg ccgtcaatga agaaaacgaa gagagattga atgagtatgt 29401 tcatgcaggg ggcaaagtga agctcattga ccatcataaa acagcccttc atttgaatga 29461 gcatgaatgg ggatttgtcc aggtggaata cgatgatgga aggctcacat ccgcgacatc 29521 gcttttatat ggctatctcg ttgaaaatgg cttcatgaaa ccgacaaacg ccttagatca 29581 attcacagag ctcgtccgcc aatacgatac atgggagtgg gagcggtacg atcaaaaaca 29641 ggcgaagcgg cttaatgatc ttttcttttt gctgtcaatc gatgaatttg aagcaaaaat 29701 gatccagcgc ctttccacgc atgacgaatt tttcttcgat gattttgaag aaaaactgct 29761 tgatttagaa gacgaaaaaa tcgagcgcta cctccgcaga aagaaaaggg aaatggtaca 29821 aacctttgtt cacgaacact gtgtaggcat cgttcacgct gaatcgtacc attcagagct 29881 ggggaacagg ctagggaaag ataacccgca cctcgattac attgcgattt tgagcatggg 29941 gtcaaaacga gtcagtctcc gcaccattca tgattacatc gatgtgtcag aaatcgccgg 30001 ccgatatggc ggcggagggc atgcaaaagc gtccggctgt tcaataaccg atgaagtata 30061 cgagttgttt gtagctgaag ctttccgtat tgatcctgta cggccggatg ccttccgtaa 30121 catctataat ctaaagggat ctgcgaatgg atcattatat gaaaatcgcg cacaaatgag 30181 attttttctt ttccctttag acaacgaatg gaatattcaa attaacggag aaacccaaga 30241 cgaaacattc gcagcgtttg aagaggcaga atggtttatt aagagaaatt atgccgcatc 30301 gctcgtgcgg gatgaagtgt ttgtcgcatt tttagcggag aatctgaagc tggcaaatca 30361 acatcgcaag taaaaaaata tgcatagggg agcgtcagtc accccctatg catatccgct 30421 agctatcgtt taaatatggc tgtacgtttc ttaatcacaa aataaagggc tatcacgaca 30481 acagccaata tcataatcgg tgttgtataa gtgcccgcta tattctcaac atcatcccac 30541 tggcttccta gctgtatgcc taaataaaca aacagaatag accatggaat gatagcaagc 30601 acagtcagta ccacaaattt gagaaaaggc attctggcaa tacctgccgg aatggatatg 30661 gcatgtctga caaccggtat aaaacgagcc gagaagacaa ctccggcgcc gtatttctga 30721 aaccagtttt ccgacatgtc gatatgatgc tttttaatca ataaatactt cccgtatttg 30781 tccagaaatg gcctgccgcc atagcggccg atccagtaaa taaagatctg ggcaatggta 30841 cccccgataa cacccgcaat aattgcgcca ataaatccaa tcgtgccttc cgataccata 30901 tagccgccat aagctaatac aatctcactc ggaatgattt caatcattaa cccaatcgca 30961 atacccgcat atcccatgtt cgtcagccat gttaaaattt cgcttatcaa actgcccaca 31021 ttcttcacaa cctgtcctaa tctttttcac tattatatga ctgattgacg agcaagatgg 31081 ttacaatttt tttaccgcag catttctttc gtttcccgtt tgatcacatc ttctaaatag 31141 gccaaaagct gagatctcat ttcggaacgc attaagccga tttcggtgct cgctttaaaa 31201 cagcctagct tatcgccaat gtcatatcga tttccttcca gcagccgggc atggatcggc 31261 tccttacggc aaacctcacg aagcgcatct gtcagctgaa tttcgttgcc cgcgcctctg 31321 ccaattgtct tcaaaacgga gaagatcgaa gaattcagca cataacgtcc cattactgcg 31381 atttccgaag gtgcttcttc aggagaaggc ttttccacta aatcgttcac ttcatataca 31441 tgcccttgag accctgatgt atttataata ccatatttgc tgacatcctc agggagaact 31501 gactgtacac cgacaacctc tgtgccataa acgtcatata catccattaa ttgccgaaga 31561 gccggtgttt cagacaccat aatatcatca cctaagagaa cggcaaaagg ctcatctccg 31621 ataaaatgct ccgcacacag caccgcatgg cctaatccga gcggttcttt ctggcggatg 31681 taatgaatgt tggccaaatc ggcaatctgc tgcatttcct taagtgtctc cgtcttgcct 31741 ttttcccgga gattgaattc caattccgcc gaccgatcaa aatgatcttc aatcgagcgt 31801 ttgtttctcc ctgtaataat cagtatatct tcaattcctg actctgcggc ctcttctaca 31861 atatattgga ttgctggttt gtcgacgatt gggagcattt ctttaggctg cgcctttgtc 31921 gccggcagaa atctcgttcc taaacccgct gcgggaataa ctgcttttct cacttttttt 31981 ctcattcatc ctcactcctg atcctgtatg tttttcagtg aatctccaaa tacccagatt 32041 cggtttccga taaaattcat catcattccg ccgatagtgg cggcgagctt actcaccaaa 32101 agcgagcagc cgcaattttg aaacaaataa agcaacaaaa aggtgatccc cgacgcggca 32161 atattaatca tgagaaaacg cacgacctct ttcccgtcag ccttaccttt cacacaaaac 32221 gtccaattcc ggttccacac atagctgttg atgatacctg cagtatagga gcagatctgc 32281 gccggcagat aagagacatg acaagcggta agaagaaaga agacaccaaa atctatcagc 32341 gtattgccga cgcctacggt gcaaaaacgg cctaatgtct ttattttttc tttcagcgta 32401 acgaacctcc cttcataaaa gatgcgagtg gcagtcatat ttgttgatat ggattactat 32461 agcggacagt gttgaataaa caattaataa aatatgaaca aaacatgaaa aagcgggtat 32521 accgctcaat aattcttata cacttgaaaa aaacagccgc attgaacggc tgttttttgt 32581 gtctgaaaac atacaaatat aaacggagtg ttagccccat cttatcaatg aataaatgta 32641 tccagttcct ttgtagaatc gaacactaac tcctccaaaa gtttctatac acaatttttt 32701 taatgatgta ggatgttaga taaagggata tcttggataa tgatgtaatc tccgttcaat 32761 gtgattagtg ggaggccatg aacaatcctg tctttttatt ttctggacaa tggtcgctag 32821 gaatggggaa gtttttttga acaattttga aggagtggtg cgatctcctc gaagaaagga 32881 gagaatggag acacatgaag atgagctttc agaacaactg ggaacattgc taaacagctt 32941 ccggctaatt tatgcatgcg atcttcatga cctgttgtca tcaaattcca aaagaaaatc 33001 ccccatttta aggaaaaagg aggatgtgaa gtgatgagga aaaagtgtag cgtatgttta 33061 tggattcttg ttttattatt gagctgctta tctgggaagt ctgcgtatgc tgccactagt 33121 actacaattg caaaacatat agggaattca aatccgctta tcgaccatca tttgggagcg 33181 gatccggttg cgctgaccta taacggaaga gtctacatct atatgtcaag tgatgactat 33241 gaatataata gcaacggaac aattaaagat aattcatttg ccaatttgaa tagagtattc 33301 gtcatatctt cagcggatat ggtgaactgg acagaccacg gagccattcc ggtagcaggt 33361 gccaatggag ctaatggagg ccgtggaatt gcaaaatggg cagatgcgtc atgggcaccg 33421 tcaatcgcag ttaaaaaaat taatggcaag gataaattct tcctttattt cgcaaacagc 33481 ggcggaggta tcggggttct caccgcagac agcccgattg gtccatggac cgacccaatc 33541 ggaaaaccgc tcgtaacgcc aagtacgcca ggaatgtctg gtgttgtatg gctttttgat 33601 ccggcagtat ttgtagatga cgacggaacc ggttacctgt atgccggcgg aggcgttcct 33661 ggcggttcaa atccaacgca ggcacaatgg gccaatccta aaacggctag agtcataaaa 33721 ttggggcctg atatgacgag tgttgttgga agtgcatcta caattgatgc gcctttcatg 33781 tttgaagatt cgggattgca caagtataac ggaacatatt attactccta ttgcattaat 33841 ttcggcggca cgcacccggc cgataaaccc ccgggtgaga tcggctacat gaccagttca 33901 aatcccatgg gcccctttac atatagaggg cacttcctga aaaatccggg tgcatttttc 33961 ggaggcggcg gaaacaacca tcatgctgtt ttcaatttta aaaacgagtg gtatgtggtg 34021 taccatgcgc aaactgtcag ttccgctctg ttcggggccg gcaaaggata ccgttctcca 34081 catattaata agctggtgca taacccagat ggatccatcc aagaggtagc agcaaattat 34141 gcaggtgtaa cacaactttc caatttgaat ccttataacc gggtagaagc tgaaacgtct 34201 gcttggaatg gacgcatttt gacagagaag tccacagcac ccggcgggcc agtaaataat 34261 cagcatgtaa caagcattca aaatggagac tggattgctg taggaaatgc agacttcgga 34321 gcggtcggtg ccaggtcatt taaagcaaat gtagcatcca cttcaggcgg gaaaatagaa 34381 gtgcgcctcg acagtgcaga cggtaagctt gttggaactc tgaatgtacc ttccacaggc 34441 ggagcgcaaa cgtggagaga aatagaaact gcagtaagcg gggcaaccgg tgtgcacaaa 34501 gtattctttg tatttaccgg aacaggtaca ggaaacttgt ttaattttga ttactggcag 34561 tttacgcaaa gataggactc gtaatgggac cgcttaaaaa cgaggcgggt gaagtacggg 34621 ccagcaccgg aacagcccgc cattatggat atgccatgca gattttttaa taccgtaaaa 34681 gacacatgac gaaggagagg aataaatgat tccacgcata aaaaaaacaa tttgtgtact 34741 attagtatgt ttcactatgc tgtcagtcat gttagggcca ggcgctactg aagttttggc 34801 agcaagtgat gtaacagtta atgtatctgc agagaaacaa gtgattcgcg gttttggagg 34861 gatgaatcat ccggcttggg ctggggatct tacagcagct caaagagaaa ctgcttttgg 34921 caatggacag aaccagttag gattttcaat cttaagaatt catgtagatg aaaatcgaaa 34981 taattggtat aaagaggtgg agactgcaaa gagtgcggtc aaacacggag caatcgtttt 35041 tgcttctcct tggaatcctc caagtgatat ggttgagacc tttaatcgga atggtgacac 35101 atcggctaaa cggctgaaat acaacaagta cgcagcatac gcgcagcatc ttaacgattt 35161 tgttaccttc atgaagaata atggtgtgaa tctttacgcg atttcggtcc aaaacgagcc 35221 tgattacgct cacgagtgga cgtggtggac gccgcaagaa atacttcgct ttatgagaga 35281 aaacgccggc tcgatcaatg cccgcgtcat tgcgcctgag tcatttcaat acttgaagaa 35341 tttgtcggac ccgatcttga acgatccgca ggctcttgcc aatatggata ttctcggaac 35401 tcacctgtac ggcacccagg tcagccaatt cccttatcct cttttcaaac aaaaaggagc 35461 ggggaaggac ctttggatga cggaagtata ctatccaaac agtgatacca actcggcgga 35521 tcgatggcct gaggcattgg atgtttcaca gcatattcac aatgcgatgg tagaggggga 35581 ctttcaagct tatgtatggt ggtacatccg aagatcatat ggacctatga aagaagatgg 35641 tacgatcagc aaacgcggct acaatatggc tcatttctca aagtttgtgc gtcccggcta 35701 tgtaaggatt gatgcaacga aaaaccctaa tgcgaacgtt tacgtgtcag cctataaagg 35761 tgacaacaag gtcgttattg ttgccatcaa taaaagcaac acaggagtca accaaaactt 35821 tgttttgcag aatggatctg cttcaaacgt atctagatgg atcacgagca gcagcagcaa 35881 tctacaacct ggaacgaatc tcactgtatc aggcaatcat ttttgggctc atcttccagc 35941 tcaaagcgtg acaacatttg ttgtaaatcg ttaagagcac aaagacacac ataaataata 36001 gagtgtctga attggcgatt ttccgattgg gaaatcgctt ttttattttg ttgctgaatt 36061 acaggaagaa gaaaggatgt acataaaaac agcaaagctt tattcttcat cttttctagt 36121 ttacataata tatattctag gaagtaaaca aaataaataa atttctgtct caatatcaaa 36181 gtatacttaa gttagtgaga cagaaattga aattttgaaa tattactgct gaatgtcaaa 36241 tcaaaaaaat ggtgttgtca atccataata aactgcttct aaatcctcca gcgtcatatc 36301 gccatatgcg catttgataa cagaatcagc aaacacatca tagtcataat ctgtagaaaa 36361 tccttgctgc agctgttttt cgtaaacttc gatctgatct ttttgatgct ggatgtcttt 36421 ttccttacct ggatagtcgg gaccatttat catattactc atttttttgt acagcactat 36481 atactgtttc agtatttcat ccacaacgca aacctcctat tagatgataa aaacggacat 36541 cgttactgat gtccgccaaa aaaagcttaa ctaatttggt tctgttcccc aaatcagttt 36601 tccttgatca tataatgtga tttttttcgt tgttttaaac gtatttgatt tgaaaaagga 36661 ataatcatcg ccgctttgtg cataattgct ccagtcatca ttgtgaagac gaagctgaat 36721 attccctgtg cttgctcccg gtgccagcgt tccgttttta aatccaagtt ccagataggt 36781 atctgcacct tgctttggtt tatgcaacgt cacaaacttg tatgtcacat tgccgcatcc 36841 aagctgcgcg tagtcacagt caacgttttg gcctttgttt ttcgcgttat accagtaacg 36901 ggcagtgaca tcttttaaat caaccgtggt attgccgtta ttttttattt gaagctgcgg 36961 acggatttgg ttgctgttca tactcccatc ccctgctctg tattgtacag aaataccgtt 37021 ttcctgtgtg ggtttatctt ttgctggcgt ttcaggaatg tccttcgtcg aatctttggt 37081 gccgagaatg ttttctctaa cgaatgttcc tgaagcagat aaatctgaca accgccagcc 37141 gcctgtttta gatgcccccg gctttaaagc tgaggatgat tcctgcttat cagaaagatt 37201 ccagttcacc cagctgatgg tcttgctgtc gagatatttc agccattccc tcgattgatc 37261 aaggaataca ccgccattgc cagacgcgtc gcttgttccc cactctgtca caaaaatagg 37321 tgctcctttg ctgagtgcat agtttgcttt atcccgtaaa aattggccgt gtgtgccggc 37381 ataaaaatga agtgcgtaca taacgtttgc atcttttagc tggtcatcgg cagcatcatt 37441 cacatcctgg ctccatgtac cggttccgac aatgatgatg ttgtctggat catttttgcg 37501 gataacggaa atcacttctt ccgcatacgg tttaatatca cgcttccagt tcacatcacc 37561 gtttggttcg tttgcaattt cataaatgac gtttggcgtg tttccgtaaa ggcttgacat 37621 ttccttgaag aattcttttg ccttctcttt attttggttt ggattaccgt catttaagat 37681 atgccagtca atgatgacat atatcccaag ctcttttgcc gcttcaaccg cttctttcac 37741 tttatttttc acggacgggt tgtcaatata accgccatct gccgtataca tcgctgcacg 37801 gaaaacggtg ataccccaat cgtccctcag ccattttaag ctgtctttat tgacatattc 37861 tccataccat tgcaatccgt gtgaactgat ccccttcagc tgtaccgctt taccgtctcg 37921 gttaacgagc tgtgtacctt ttatgctaag ctggccattc ttggctactg gcgtttttgt 37981 ccctgctgct gatgccggcg aagccagcat gccgcccatt gtcaataacg taatcaataa 38041 acacgtaata aaaatagaga ttgaccgttt catatctgat cttttcctcc ttcgcatcat 38101 tttggctcta cacttcttat gagcacgaac tcattgtaaa aatctttctc atgattgtct 38161 atcaacctaa tttcttgttt ttgggaggtt taaaagtctg tcaatttgtc tatctccatt 38221 gaataagaca cacatgatac atatagaaca aagaaaaccg aactgaattg ggactttaca 38281 cgtcattttt cattcgagtc gaaaaattaa atttatttcc aataatgaaa aagctgcatt 38341 caactattga atgcagcttt gttttatatt taaattatgc ttcttgtttc tcatcttccc 38401 atgtttcagc gtttttcagc cctgggatgt ttttcgcttt aaacacagga tcaagtcctt 38461 gctttcgctg tttcgcgtaa tctttataca ctttgtaagc a //