LOCUS       gnlProkkaHBHHAHAJ_1    12184 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HBHHAHAJ_1.
ACCESSION   gnlProkkaHBHHAHAJ_1
VERSION     gnlProkkaHBHHAHAJ_1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-29 00:09:23
            Original ID  :: gnl|Prokka|HBHHAHAJ_1
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 4025537
            Orig. end    :: 4037721
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12184
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:7184]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..7184
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..12184
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12184
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="10"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             2341..3162
                     /NRPS_PKS="Domain: PKS_KR (7-160). E-value: 1.3e-07. Score:
                     23.5. Matches aSDomain: nrpspksdomains_ctg1_4238_PKS_KR.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     239.4; E-value: 7.1e-73)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_4238"
                     /sec_met_domain="adh_short (E-value: 9.6e-30, bitscore:
                     101.9, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 7.1e-35, bitscore:
                     119.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGRLENKTAVITDAATGIGQATAEVFANEGARVMIGDINTDQMEE
                     TVDAIRKNGGQAESFHLDVSDENSVKAFADQIKDACGTIDILFNNAGVDQEGGKVHEYP
                     VDLFDRIIAVDLRGTFLCSKYLIPLMLENGGSIINTSSMSGRAADLDRSGYNAAKGGIT
                     NLTKAMAIDYARNGIRVNSISPGTIETPLIDKLAGTKEQEMGEAFREANKWVTPLGRLG
                     QPKEMATVALFLASDDSSYVTGEDITADGGIMAYTWPGKMLIDEKWKEETK"
     aSDomain        2362..2820
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_4238_PKS_KR.1"
                     /evalue="1.30E-07"
                     /label="ctg1_4238_PKS_KR.1"
                     /locus_tag="ctg1_4238"
                     /protein_end="160"
                     /protein_start="7"
                     /score="23.5"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="TAVITDAATGIGQATAEVFANEGARVMIGDINTDQMEETVDAIRK
                     NGGQAESFHLDVSDENSVKAFADQIKDACGTIDILFNNAGVDQEGGKVHEYPVDLFDRI
                     IAVDLRGTFLCSKYLIPLMLENGGSIINTSSMSGRAADLDRSGYNAAKG"
     CDS             complement(3298..3522)
                     /locus_tag="ctg1_4239"
                     /transl_table=11
                     /translation="MENNNHLSELNVKEMEQIDGGGWRSALGEAFSGALVGASTVGVGG
                     AAVGGPVGGAGGAITGGIVGGIVGGINAW"
     CDS             complement(3539..3769)
                     /locus_tag="ctg1_4240"
                     /transl_table=11
                     /translation="MNEKSIKDVELQALTLEEAEQIDGGSYAKYLGSAVVTGAGAGVVG
                     GVPGVILGAHAGAIAGSVGYLGGSLIAGKWL"
     CDS             complement(3959..4384)
                     /locus_tag="ctg1_4241"
                     /transl_table=11
                     /translation="MKDERISHIENKIGHESFLLVIALVFVSFILSIMFKMPSTLMTII
                     ILFVGSGYYGLRAMSKGILRVNLKKKKKSSYFLLIVFTFILYMATSVLFKIITFPFTTK
                     EFLFQILMYILWLIPFSLIMYTTYKFSNRQQKKELEN"
     CDS             complement(4374..4592)
                     /locus_tag="ctg1_4242"
                     /transl_table=11
                     /translation="MNNNLKLERTRANLTQEQLAEKIGVTRQTIGLIEKGKYNPSLQLC
                     LKICIELKVTLNDVFWTHNREEETDEG"
     CDS             5001..7184
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 300.7; E-value:
                     3.6e-91)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_4243"
                     /sec_met_domain="Peptidase_C39 (E-value: 6.3e-43, bitscore:
                     143.8, seeds: 36, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR01193 (E-value: 2.6e-237, bitscore:
                     787.7, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFFNRYHCVRQLDQKDCGAACLSTIAKHYGSKLSLAYIRDIAGTD
                     TQGTSALGMVKAAEQLGFSAKAVRAEHTAFDQSFTLPAIAHIIIDQQLLHYVVIHKISK
                     DKIIIADPGKGIVTYQKDDFFKIWTGILILLAPTETYKKQTETSNISADIFRLILQQKS
                     LIIHTFLASFIITIFGILGTFYFQTIIDQILPNGLSNTLHILSIGLLIMYLFKVFLIGF
                     RQYLMILLGQKLSISIMFGYFQHVLTLPMKFFSNRKVGEIISRFTDANKVIDAVVSASL
                     SAILDTIMLIMVGIFLYLQNTTLFLITLAFIPFYILTVWIFIKPYENINNSEMENNAQL
                     TSKIVETLNGIETVKAYNAEYMMSFETEKRFVKYLRSAFKHGVIDNLQSSIKMFLDLAS
                     GALILWIGSTQVMKGTLTIGQLITYNALLTYFLNPLQNIIGLQSKLQSASVASKRLGEI
                     LKLEPELKENKERITSTSSITGPLSFNKINFRYGTRRLILKDITLHIQKGEKVAFVGES
                     GSGKSTLTKLLMKFYTAESGEVLINGYHINDIHTNALRESISYIPQESHFIQGSILENL
                     LLGNSGSFTFEEIIEVCKQTNVHDFVNDLPMRYDTLVEENGSNLSGGQKQRLAIARALL
                     RKPNILIMDESTSNLDTTTEQGISKMIYAQTVDVTTIIIAHRLSTIMNCDKIFVMENGE
                     IIEYGNHNDLLKKKGKYYELWENQMPSREMVTI"
     CDS             7288..7653
                     /locus_tag="ctg1_4244"
                     /transl_table=11
                     /translation="MILKTAADIQYTKPNSNVTNEVAGKVKTVDIKQVDKVKKGDTLLT
                     LDNTEIQAQKKAVKADIKDVKEQAALNKTLKKSIENDKNLFSEDDHSGYQDQYLSYEKQ
                     SNLLESSKENAKTQQKK"
     CDS             7628..8578
                     /gene_functions="transport (smcogs) SMCOG1029:RND family
                     efflux transporter MFP subunit (Score: 56.7; E-value:
                     3.2e-17)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_4245"
                     /transl_table=11
                     /translation="MQKLSRKNSLDKTKTKVKRKLQRISYLQDSIKNNKSFAKQDDKYS
                     SYYSSYQTNKQNLEQQLDDLRKMKDELDKHSFSQQKENLNGQLESLKQDMLVKLSEEKD
                     ELNQSLDEINSSMKSDDSDSDSDNSEETNYKLSIEQLKTNLLNQTSQKQTDLQTTLKSK
                     EDDLKMIDLQLEKYKIKATSDGYVNVLTNISPGDNLQAGTAILAIIPDKEKLKANIYIP
                     SHEITNINEKDEVRFHIENTNQTIKGVITKISPDSISDQNGQKFYIAESTIESKEIEKN
                     NGTKIHLKNGMQTDVSIIVDSKRYIDYFLDVLHLR"
     CDS             8680..8868
                     /locus_tag="ctg1_4246"
                     /transl_table=11
                     /translation="MSQNKLLFLLFLFSSIVRLFFNTVLSPTVSWKSWTVNIVFILLSL
                     LFLNLTLKERKSKDQVS"
     CDS             complement(8903..9682)
                     /locus_tag="ctg1_4247"
                     /transl_table=11
                     /translation="MLAPVNVNLTPIEQEIYGHYRALYTYAIILYWLNEDADASPEVIS
                     QKVWELVSQKRFYWLFGQAPSRKRQEDKQIDRRVVRTREALQRALLDVLAEKKDYTAIT
                     ISYMTRKSNIRRATFYDYYANKEELLQTLIQRSCAEIIDHLTIASSPNTFSLKEAEKAL
                     ANLLSDLSNMPIVHFLNREWGVPHVIPNMFKALKSFYLHQQTNIPAEKKLYAYYVSAMI
                     IGLILYRLDEGKAHAPEVLAREFLQFLDVKKYKVVLL"
     CDS             complement(9705..10046)
                     /locus_tag="ctg1_4248"
                     /transl_table=11
                     /translation="MAESAEAQVKQALLALLEERDIQHITMKEIAEKAKVSRGTLYLYY
                     EEKFSIIEDMVEDMKEGLGEALYDAFKHMDTLHLNKKRHTVHPTLSFVHEHRFFLGTMM
                     NRGQFHRFF"
     CDS             10188..11474
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017:aldehyde dehydrogenase (Score: 293.7; E-value:
                     3.1e-89)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_4249"
                     /sec_met_domain="Aldedh (E-value: 2.2e-97, bitscore: 324.5,
                     seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEQQIKDDIQRVFQLQKKQQKALRASTAEQRREKLQRFLDSVIAH
                     EEEIIEAIRKDVRKPYHEVKKAEIEGTKKAIRDNMNNLEQWMAPKEVGSSLSPDANGIL
                     MYEPKGVTLILGPWNYPFMLTMAPLAASLAAGNSAIVKLSDFTMNTSNIAAKVIRDAFD
                     EKEVAIFEGEVEVATELLDQPFDHIFFTGSTNVGKIVMTAAAKHLASVTLELGGKSPTI
                     IDSEYDLMDAAKKIAVGKFVNAGQTCIAPDYLFIKKDVQDRFAGILQTIVNAGFMEDDR
                     NPDRSKFTQIVNDRNFNRVKDLFDDAIEKGAEVVFGGVFDASDRTISPTVLKNVTPDMK
                     IMQEEIFAPILPMMNYEDIDEVIDYVNDRDKPLALYVFSHNQDLIDNVLQHTTSGNAAI
                     NDVVVHFSDVNLPFGGVNTSGIGSYHGVY"
     CDS             11715..12182
                     /locus_tag="ctg1_4250"
                     /transl_table=11
                     /translation="MEKPAGFWIRAVASIIDGFIIALFSFIMIFINTFIVLPLIDAAGT
                     HMTEAQYEFFMLIIGTIPVLAIIFIFAILYYSLLTSSNMQATLGKKLMSIIVVNQHGER
                     ISFWHSFGRFFAYTLSKILYIGFIMAAFPSKLALHDYICGTKVVYKNKYLD"
ORIGIN
        1 cgatgagaag cgcctgattg tacagaaggt ttgtgtacag gctcagcttc tctttatctt
       61 gttcaaacgc gtcctgcagc gtttggaata cctcgtgatt cgggttgatt tccagcactt
      121 tttccgcctt cacattttgg ctgtcaggca ttgcgtttaa gattttttcc atctcaattg
      181 tcacttcgcc gtcagcagca aggcagactg gatgtgattt aagccgtttt gagattctga
      241 cgtttttcac tttgtctgac agaatgtttt tcatttcctc aaacagatcc ttatacttgt
      301 tttcctcttc ctcggactgc ttttgatcct catccgtgtc tatgccaagg tctccgcttg
      361 atacggactt gaattctttt tcctgataag aagccagcat tttaattgca aactcatcga
      421 tgtcctcagt aaagtagagg atttcatagc ctttgtccgc caccatttcc gtttgcggca
      481 gtttctcaat gcggtcgtaa gaatcaccgg tcgcgtaata aatgtatttt tgctcctctg
      541 gcattctgga aacatactcg tctaagctga ccagtttttt ctcttttgaa gagtagaata
      601 ataggagatc cttcaattga tccttattcg cgccaaaatc attatacacg ccgaatttca
      661 gctgtctgcc gaacgacttg tagaacgtct cgtatttctc gcggtctttt ttcaacaggc
      721 tttgcagctc gcttttgatt ttcttgctga tgtttttcgc gatcagcttc agctggcggt
      781 catgctgcag catttctctg gaaatgttca gcgacagatc ctcggaatcg accatgccct
      841 tcacaaagct gaagtggtcc ggtagcaggt ctgcgcactt attcatgatc agcacgccat
      901 tggaatacag ctccaagcct ttctcatatt ccttggaata gtagtcaaac ggcatgtttt
      961 cagggatgaa tagaatcgcg ttgtagcgaa ccgctccatc cacactgata tgaacgtgtg
     1021 tcagcggttt atcaaacccg taatgctttt cagcatagaa tttttcataa tcctcatctg
     1081 tcagctcgct tttgtttttt ctccagatcg gcaccatgct gttgaccgtc tgctcttcct
     1141 gcacctcttc gaattcattt tcgctgcctt ccttcggctt attaatggtt gtatccattt
     1201 tgatcgggta gcgaatgaag tcggagtact tcttgatgat cgcttttaaa cgatattcct
     1261 ctaaaaactc gtcatagctg tcatcttctg tgttctcttt gattttcagg ataatgtctg
     1321 taccgacaga atccttttca cacggttcaa tcgtatagcc gtctgcaccc gcagactccc
     1381 atttataagc ctgttcgctg ccaagcgctt tactgatgac tgtcacgaca tcggcaacca
     1441 taaatgccgc gtaaaaaccg acaccgaact gcccgataat gtcatgtccg tctttcagct
     1501 cgttttcctt tttaaacgcg agggaaccgc tttttgcaat tgttccaaga tgctgttcaa
     1561 gctcatcctt tgtcattccg atccccgtat cagagatggt taatgttctc gcatctttgt
     1621 cagctgcgac ctttatgtag taactgtctt tatcaaacgt aagcgcatcg tccgtaagcg
     1681 ctttgtaata gattttgtca atcgcatcac tcgaattgga gattaactcg cgcaggaaaa
     1741 tttctttttg ggtataaatg gagttaatca tcatatccag caagcgttta gactctgctt
     1801 taaactcttt tttcgccact cttgatcgct cctttaccat tatgtaaacc ctttttagca
     1861 tctatttatc acataagatg acaattgtca attagattga tagatgcata tatatgtaaa
     1921 tttaacatta gttggatttg ttttcactct ttttctcact cattctcata aaaaagagag
     1981 gcttcatcat cctctctttt tttctgtgtc attccagcgg ccaaactccc gcttcatcca
     2041 tatatgcacc gggtagaaaa acaaaccgaa cggtatcaaa aacaaaagat tatgccatga
     2101 agcattcaga aatgcgcttg cagtcaccgg aaacgtaatc tcttgcaata caaaagagat
     2161 gacagtcagc acaacaaacg ccgatggaat cgtgataaag caataaaact tgagctcctt
     2221 cttatgctgt acttttaaaa cacacaaccc tcccaacaat ttcccaatcc atcttaacat
     2281 atgttggcag ttctttttct tcatgtttat cactgccaaa tagaaaaagg aggtctcgtc
     2341 atgggaagac ttgaaaacaa aaccgcagtg atcacagacg ccgcgacagg cattggacaa
     2401 gcgacggcag aggtttttgc caatgaaggc gcgcgtgtaa tgatcggaga tatcaataca
     2461 gatcaaatgg aagaaacagt ggacgcaatc agaaaaaacg gaggacaggc cgaatccttt
     2521 cacctcgatg tgtcagatga aaacagtgtg aaagcttttg ctgaccaaat caaggatgca
     2581 tgcggaacga ttgatattct gtttaataat gccggcgttg atcaggaggg cggaaaggtg
     2641 cacgaatatc cggttgacct gtttgaccgc attatcgccg tcgacctgcg cggcacgttc
     2701 ctttgcagca aatatctgat tccgctcatg ctcgaaaatg gaggttctat catcaacacc
     2761 tcctccatgt caggccgcgc cgcggatctt gaccgctccg gctataacgc ggcaaaaggc
     2821 ggtatcacca acctgacaaa ggcaatggca atcgactacg cacgaaacgg catccgcgtc
     2881 aattccattt caccaggtac gatcgaaacc ccgctgattg acaaattagc aggcaccaaa
     2941 gaacaggaaa tgggcgaagc attccgcgaa gccaacaaat gggtcacgcc gctcggccgc
     3001 cttggccagc cgaaggaaat ggcgacagta gcgctgttcc tcgcgtcaga cgacagctca
     3061 tacgtcacag gagaagacat caccgcagac ggcggcatca tggcgtatac atggcctggg
     3121 aagatgctga ttgatgagaa gtggaaggaa gagacaaagt aactgagata gtcagttaaa
     3181 agaagaattt aaaaacatta tgtatatata taaatacaaa tataacaaga cagggaaaag
     3241 atatactctt gccggtcttg ttacataatg ttcaagctag ttctttatgt atttttatta
     3301 ccaagcgttt attccgccaa ctataccgcc aactatgccg ccagtaattg ctccgccggc
     3361 accaccaacc ggtccgccaa cagctgctcc accgacgcct actgtggaag caccgactaa
     3421 tgcacctgaa aaagcttcgc caagggcact tctccagcct ccgccatcaa tttgttccat
     3481 ttcttttacg ttcaattctg aaagatgatt attattttcc atttatgcta ttccctcttt
     3541 aaagccattt tccggcgatt aatgacccgc ctaaataacc aactgaccct gcaattgcac
     3601 ctgcatgggc accaagaata acacctggaa ctcctccgac tacacctgcg ccggcacctg
     3661 taacaactgc actgccaaga tatttcgcat aacttcctcc atcaatttgt tcagcttctt
     3721 caagagtcaa tgcctgaagt tcaacgtctt ttatgctttt ttcgttcatc aatattcctc
     3781 cttaaagtta tttaggtaaa taataactag tataaattta tcatgggaat tataatatta
     3841 cataataaac cctaaataaa tagttttttc cataaaatta actataacct atcgatcaat
     3901 ttatatatag taaaagagag cttaacctaa ttcagttatt taggttaagc tctcttaatt
     3961 aattctctaa ttcttttttc tgctgcctgt ttgaaaattt atatgtagta tacatgatga
     4021 gactaaaagg aattagccat aagatataca taagaatttg gaataagaat tctttagttg
     4081 taaaaggaaa tgtaatgatt ttaaataata ccgacgttgc catatacaga ataaaagtaa
     4141 aaacaattaa aagaaagtac gaactcttct tcttcttttt cagattgact cttaaaatac
     4201 cttttgacat agctcttaat ccataatatc cgcttccaac aaacaatatg ataattgtca
     4261 ttaacgtgct cggcatttta aacataatcg aaagtataaa agagacaaaa accaaagcaa
     4321 ttactaaaag aaagctttca tgacctatct tattttcaat atgacttatt ctctcatcct
     4381 tcatcagttt cttcctccct gttatgcgtc caaaatacat cattcagagt aaccttcaat
     4441 tctatacaaa ttttcaaaca taattgtaaa gaaggattat acttcccttt ttcaattaat
     4501 ccaatcgtct gtcttgtcac tccaattttt tcggcaagtt gttcctgtgt taaattcgct
     4561 cttgttcttt ccaacttcaa attattattc attggcaagt ctccattggt ttatttatct
     4621 gtagcatatc atatataaaa atcatgcaaa ttatatattg catttatcca tatatatttt
     4681 acattttgtc tattatatct tacaataaat ttaacatcaa taggggttgg taaaatgaaa
     4741 ttgttctata gctatataat cgcagggggt ttattttgta tatctctttc ttattttttt
     4801 cacttaggtg tatttaatct tgctttatat cttatctaca tcaattacgc atttatatta
     4861 tataaacgtg acaaaagctc taaataacaa taaatattta ccttaaaaag gttgacaaac
     4921 catgaaaatg taataaaatg atgtctattc tttatattat atatattcta aaaaatgacc
     4981 ttcattatgg agagtagtat atgtttttta atagatatca ttgtgtacga caacttgatc
     5041 aaaaagattg tggagcagcc tgcctatcaa caattgcaaa acattatggc tcaaagctct
     5101 ctctagctta tatacgtgac attgctggaa ctgatacaca aggtactagt gctcttggaa
     5161 tggtaaaagc cgccgaacag ttggggtttt cagcaaaagc tgtacgtgca gagcatacag
     5221 cttttgatca gtcatttact cttccagcaa ttgcacatat tattatagat caacaattat
     5281 tgcattatgt tgttatacat aaaattagta aagataagat tatcattgcg gaccctggaa
     5341 aagggatcgt tacatatcaa aaagatgatt tttttaagat ttggacaggc atcttaatac
     5401 ttttagcacc tactgagact tataaaaaac agaccgagac aagtaatata agtgccgata
     5461 ttttcaggtt gattcttcag caaaaatcgt tgattataca tacgttttta gcatccttta
     5521 ttattaccat cttcgggatc ctcggtactt tttactttca gacgatcatc gatcaaatcc
     5581 tgcctaatgg attaagtaac acattacata ttctttcaat cggccttttg attatgtatt
     5641 tatttaaggt tttcttaata ggttttaggc aatacctaat gattctccta ggacaaaaat
     5701 taagtatctc cattatgttt ggatactttc aacatgtgct tacattgcca atgaaatttt
     5761 tcagcaatcg aaaagtcggc gaaattatat ccagatttac tgatgctaat aaagtgattg
     5821 atgcggttgt cagtgcatcg ctttcggcca tactcgatac cattatgctt attatggttg
     5881 ggattttctt atatctgcag aatactactt tatttctcat cacattggct ttcatacctt
     5941 tttatatttt gacggtttgg atttttataa aaccttacga aaatataaat aactcagaaa
     6001 tggaaaacaa tgcgcagctg acttcaaaga ttgtcgagac gcttaacggc atcgaaactg
     6061 ttaaagcata caatgcggaa tatatgatgt catttgaaac agaaaaaaga tttgtcaaat
     6121 acttacgatc agcttttaaa catggagtta ttgataatct tcagagttcc ataaaaatgt
     6181 ttttggattt agcaagcggt gcattgatat tgtggatcgg atcaactcag gtcatgaaag
     6241 gcacccttac tatcggtcag cttattacat ataatgcctt attaacctac ttcttaaatc
     6301 ctttacaaaa catcatcggc ctacaatcta agcttcagtc agcttctgtt gcgtccaaaa
     6361 ggctcggaga aattctaaag ctagaacccg aattaaaaga gaataaggaa cgaataacat
     6421 cgacgtcgtc tattacaggt ccgctttctt ttaataaaat caattttcga tacggaactc
     6481 gaaggctcat cttaaaagat attacactgc atattcaaaa aggagagaaa gttgcctttg
     6541 ttggagaaag cggttcagga aaatctactt tgactaagct tttaatgaaa ttttatacag
     6601 ctgaatcagg tgaggtttta atcaatggtt atcatataaa tgatattcac accaatgcgt
     6661 taagggaaag cataagttat atacctcaag aatctcattt tatacaagga tcaattcttg
     6721 aaaacctttt gcttgggaac tcaggaagtt ttacctttga agagattata gaagtatgca
     6781 aacaaacaaa cgtacacgat tttgtcaatg atttaccaat gagatacgat actctcgtag
     6841 aggaaaacgg gtctaattta tctggaggcc agaagcaaag acttgcaatt gccagggcat
     6901 tattaagaaa acctaacatt cttataatgg atgaatcaac aagcaacctc gatacgacga
     6961 ccgaacaggg aatatcaaag atgatttacg ctcagactgt cgatgtaact acaattataa
     7021 ttgctcatcg tttaagtaca attatgaatt gcgacaaaat atttgtcatg gaaaatggag
     7081 aaatcataga gtatgggaac cacaatgatt tattgaagaa aaaaggaaag tactatgagt
     7141 tgtgggagaa ccaaatgcca tcgagagaga tggtgacaat ttagatgaaa cgtaactttt
     7201 tcaatttaca tgatttgaag gatagcagag aattctacga atcaaaaccc aaaccaattg
     7261 gtgttttctt tctatggaaa gaaagaagtg attctaaaaa cggcagctga catccaatat
     7321 acgaaaccta acagcaacgt aacaaacgaa gtagccggca aagtaaaaac agttgatatt
     7381 aaacaggttg ataaggtgaa aaagggggat actctattaa ctctagacaa tactgaaatc
     7441 caagcgcaga aaaaagctgt taaagcagat atcaaagatg taaaagaaca agctgcgtta
     7501 aacaaaactc taaaaaaaag tattgaaaat gacaaaaatt tattcagcga ggacgatcat
     7561 tcgggttatc aagatcaata tctctcatac gaaaaacaaa gcaatttgtt agagtcatca
     7621 aaagaaaatg caaaaactca gcagaaaaaa tagtctggat aagacaaaaa ccaaagtgaa
     7681 acgaaagctt caaagaattt cttatctgca agactcaatt aaaaacaata aatcctttgc
     7741 caaacaggat gataagtaca gttcttacta tagtagttat caaactaaca aacaaaatct
     7801 agagcagcag cttgatgatc tacggaagat gaaagatgag ctcgataaac acagtttctc
     7861 acagcagaaa gagaatctaa acggacagct tgaaagttta aaacaagata tgctagtaaa
     7921 actaagtgaa gaaaaagacg aattaaatca atcacttgat gagattaaca gttcaatgaa
     7981 aagtgacgat tctgacagtg attccgataa ctcagaggaa acaaattata agctttcaat
     8041 tgaacagctt aaaacaaact tgctaaatca aacatctcaa aagcaaacag atcttcagac
     8101 cactcttaaa tcaaaagaag atgatctaaa gatgatagat ttacaattag aaaaatataa
     8161 aataaaagca acaagtgacg gctatgttaa tgtattaaca aatatatctc caggggacaa
     8221 tttgcaagca ggcaccgcca ttttggctat tatccctgat aaagagaagc ttaaagctaa
     8281 catttatatt ccgagtcatg agatcacaaa tattaatgaa aaagatgaag taagattcca
     8341 tattgaaaat acaaatcaaa caattaaagg tgtcattaca aaaataagtc cagacagtat
     8401 tagtgatcaa aacggacaaa aattttatat tgctgaaagc acaatagaaa gcaaagaaat
     8461 tgaaaaaaat aacggaacaa aaatacactt aaaaaatggc atgcagactg atgtatcaat
     8521 tatcgttgat tcaaaaagat atattgatta ttttttagat gtattacact tacgttaatt
     8581 tccatctaga gaaaatgtgc atatatgtct caaaagcaga tgcggatctg ctttgaggca
     8641 ttttattttt tataagaaag gtagaggact tatagaatca tgtctcaaaa caaactgtta
     8701 tttttactct ttttattctc ttctatcgtt cgccttttct tcaatacagt attgtccccc
     8761 actgtaagct ggaagtcttg gacggtgaat attgttttta ttcttttgtc tcttctattt
     8821 ctcaatctca ccttaaaaga aagaaaatca aaagaccaag tatcataacg acccaaagcc
     8881 cggatcaagt tctccgggca cttcaaagca acacaacctt atacttcttc acatccaaaa
     8941 actgcaaaaa ctccctcgcc agcacttccg gcgcatgcgc cttcccttca tcgagccgat
     9001 acaagatcag cccgataatc atcgccgata cataataggc ataaagcttt ttctccgcag
     9061 gaatattagt ttgctgatgc agataaaacg attttagcgc tttgaacata ttaggtatca
     9121 catgaggaac accccattcc cgatttagaa aatggacaat gggcatgttt gataaatcag
     9181 aaagcagatt ggcgagcgcc ttctccgctt cctttaagga aaacgtattc gggctggagg
     9241 caatcgtcag gtgatcaatg atctccgcac atgatcgctg tatcaaggtt tggagcaatt
     9301 cctctttatt ggcatagtaa tcataaaagg ttgcgcggcg gatattgctt ttccgggtca
     9361 tgtaagaaat cgtgatggcc gtatagtctt ttttctctgc caatacatcc agcaaagccc
     9421 tctgcagcgc ttctctcgtt cgaaccacac gcctgtcgat ttgcttgtcc tcctgccgct
     9481 tccttgacgg ggcctgtcca aacagccaat aaaacctctt ttgagaaacg agctcccata
     9541 ccttttggct gataacttcc ggagacgcgt ccgcatcctc attcagccaa tagaggataa
     9601 tcgcgtacgt gtacaaagcc cggtaatgtc cgtaaatctc ctgttcgatc ggcgtcagat
     9661 tcacattgac cggagccagc aaaacatcct gctgaaacac ctccttaaaa aaaacgatga
     9721 aactgtcctc tattcatcat cgtgcccaaa aaaaatcgat gctcgtggac aaaggacaga
     9781 gtcggatgca cggtgtgccg ttttttattt aaatggagtg tgtccatatg cttgaaggcg
     9841 tcatagagcg cttcgcccag cccttccttc atgtcttcga ccatatcctc aataatggag
     9901 aacttttctt cataataaag gtagagcgtc ccgcggctca ctttggcctt ttcagcgatt
     9961 tctttcattg tgatgtgttg aatatctctt tcttccaata aagcaagcag cgcctgtttc
    10021 acttgagctt cagcagattc cgccacaaaa acacccccca gtcattagac agatattcga
    10081 tatatgtacg gtaacgtata gatggttcac cgttgtcttt cttatagaaa aggtaccact
    10141 ttataatagg tccgagaaaa gaagaaagca aatgaggggg atttacaatg gaacagcaaa
    10201 taaaagacga catccagcgt gtctttcagc ttcagaaaaa acagcaaaaa gcattgcggg
    10261 catcaacagc ggaacagcgc agagaaaagc ttcagcgctt tttagattct gtaatcgccc
    10321 atgaggaaga aatcatcgaa gcgatccgca aagacgtccg caaaccatat cacgaagtca
    10381 aaaaagcgga aatcgaagga acaaaaaaag cgataagaga taatatgaat aacctggaac
    10441 aatggatggc gcctaaagaa gtcggttcat cgttaagccc tgacgcaaac ggaattctta
    10501 tgtacgagcc taaaggcgtc acactcatcc ttggcccgtg gaactatccg tttatgctga
    10561 caatggcgcc gcttgccgct tctctcgcag ccggaaacag cgcgattgtg aagctgtccg
    10621 attttacgat gaacacaagc aacattgccg caaaagtaat ccgagatgct tttgatgaaa
    10681 aagaagtcgc gatttttgaa ggagaggttg aggtggcaac cgaacttctg gatcagccat
    10741 tcgaccatat tttcttcacc ggaagcacga atgtcggaaa aatcgtcatg acagcggctg
    10801 ccaaacactt ggcatctgtc acacttgagc ttggcggcaa gagcccgaca atcattgaca
    10861 gtgaatacga tctcatggac gcagcgaaaa aaatcgctgt cggtaaattc gtaaacgccg
    10921 gccaaacctg cattgcacct gattacctgt tcattaaaaa agacgttcag gacaggttcg
    10981 caggcatttt acaaacaatt gtcaacgcag gatttatgga ggatgatcgc aacccagacc
    11041 gcagcaagtt tacacaaatc gtcaatgacc gcaacttcaa ccgcgtcaaa gacctgtttg
    11101 acgatgccat cgaaaaaggg gcggaagtgg tgttcggcgg cgtatttgat gccagcgacc
    11161 gcacgatctc gccaaccgtt ttgaaaaacg tcacgcctga tatgaaaatc atgcaggagg
    11221 aaatcttcgc accgattctg ccgatgatga actatgaaga catcgacgag gtcatcgatt
    11281 acgtaaacga ccgcgataaa ccacttgcac tttacgtatt cagccacaac caagacttga
    11341 ttgacaacgt ccttcagcac acgacatcag ggaatgccgc catcaatgat gttgtcgttc
    11401 acttcagcga cgtcaacctg ccgttcggcg gcgttaacac aagcggaatc ggttcctatc
    11461 atggcgtata ttgatttaaa gagttttctc atgagaaggg tgtatttatt caagcctcta
    11521 aataatcgta atgaagagaa tttgcatcat cttgcaggtt ctttttttat ctttatatca
    11581 cctaaataaa gagattaaaa gtgataaaat accattttca ctacgagacc aaattcctct
    11641 agtatatctc attgaaaccg cgcagcctct aacgtataat atcccagaaa acttcaaagg
    11701 agagaatatt atacatggaa aagccagctg gattttggat tcgggcagtt gcctctatta
    11761 ttgatggatt cattatagct ctattctctt tcattatgat tttcattaac accttcattg
    11821 tgttgccact cattgatgca gcaggtacac acatgacaga agcccaatat gagtttttca
    11881 tgttgatcat tggcacaatc cctgttttgg ccatcatatt tattttcgct attctttact
    11941 atagcttgct gacttcctca aacatgcaag caacattggg aaaaaaactc atgagcatca
    12001 tcgttgtcaa tcagcatggt gagcgtattt ctttttggca cagcttcggc cgtttcttcg
    12061 cttacacatt atctaagatc ttatatatcg gttttatcat ggcggccttt ccctctaaac
    12121 tggcattaca tgattatatt tgcgggacaa aggttgtcta taaaaataaa tatcttgatt
    12181 gatc
//
