LOCUS       c00032_gnlPro..        12161 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AIGEPHNL_32.
ACCESSION   c00032_gnlPro..
VERSION     c00032_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 22:50:34
            Original ID  :: gnl|Prokka|AIGEPHNL_32
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12161
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12161
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[5632:9146]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      5633..9146
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..12161
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12161
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             2..1063
                     /locus_tag="ctg32_1"
                     /transl_table=11
                     /translation="ESGKHQASGTGIGLALVRNLVELHEGEIRVESIQNEGSTFYISLL
                     TDNIYPNALHGDSTKQTEEEMISEAVPEDSQNTEPETSKPILLIVEDNEDIQKYIAESF
                     SDSFEVITGSNGEEGKQQALNRIPDIIVSDIMMPVMDGITLCRQLKEDVRTSHIPVILL
                     TAKDSLQDKEEGYEVGADSYLTKPFSASLLRSRINNLLDSRKKLIAQFQQTGTSHNPNS
                     HLDEKRSIITEALSKLDNEFIEKITQLVEDNLSSEKIDITYLSDKMCMSGSTLYRKMKA
                     LTGLSTNEYIRKVKMQNAERLLLEGKYNISEIAYKIGMNSTGYFRQCFKDEFGVSPSDY
                     LKQFTSPTPPPSS"
     CDS             complement(1032..1997)
                     /locus_tag="ctg32_2"
                     /transl_table=11
                     /translation="MLLPRKIVFFLLLFVGLSLYAQQNCFISSYVRGNFYNRGRISAES
                     LRASDDLIFLNVRPNKDGSLSFENPRIFENGKGVTSWEELIKSVRADVKGTKTKLRLGA
                     ASGEWKAMVADEAARVAFAKNIKKILEKNKLDGIDLDFEWAETEKEYEDYSLAILKMRE
                     VLGDKYVFSVSLHPVCYKISKEAIAAVDFISYQCYGPSPVRFPMEKYCSDIQMALAYGI
                     PKEKLVAGVPFYGVTKDGSKKTEAYFSFVQDGLITGPAQNEVTYKGDVYVFDGQNNIRA
                     KTRYAMDQQLKGMMSWDLATDMPLNDSRSLFKTMVEELGR"
     CDS             2322..3878
                     /locus_tag="ctg32_3"
                     /transl_table=11
                     /translation="MNKLVLTGLLAAGTMTHLQGAQPAGQRPNILFILSDDHTSQAWGI
                     YGGVLAEYAHNANIRRLAKEGVVLDNCFCTNSISAPSRASILTGLYSHRNRLYTLADSL
                     DTSIPTLATLLQANGYHTGLVGKWHIQSQPQGFDYYSIFYDQGEYRDPTFIESTDPWPG
                     NHQFGERVLGFSTDLVTEKAIRWMKEQDGNQPFLMCCHFKATHEPYDYPIRMEHLYDGV
                     TFPEPENLLDWGPETNGRSFKGQTLEELERRWRIASQDPDKWWCRYPGLPFSTEGMQRT
                     AARRASYQKFIRDYLRCGATVDDNIGKLLKALDEMNIADNTIVIYVSDQGYFLGEHGFF
                     DKRMFYEESARMPFVIRYPNKVPAGKRLDDLILNVDFAPTLAEFAGVKMENVQGDSFVS
                     NLEGNTPTDWRKEIYYRYWTNHAIRPAHFAIRSDRYKLIFYYARNLDMTDTENFDFTPS
                     WDFYDLQNDPHENHNAYNDPKYAPVIKQMKKDLLRLRKETGDTDGKYPEMQELLEKYYN
                     K"
     CDS             4562..5512
                     /locus_tag="ctg32_4"
                     /transl_table=11
                     /translation="MEERILFSQKTTIFVPVDNDSRIKPMSKDSLCAQHTDCSGCPKAM
                     ESTLIHRNLLRGQHIPKDKCTQNCMLFMIEGELLINSDEHPGTTLHEKQFILQAIGSKY
                     EILALTDVSYILFWFNELPLLCENRYREIIDQAEGPLTYTPMVMNPRLFYLINDVAAYL
                     DESTPACGKYIDLKCQEMVYMITNYYPLPQLRAFFYPISTYTESFQYFVMQNYSKAKNV
                     EEFAHLGGYNTTTFRRLFRNLYGVPVYEWMLEKKREGILEDLQHSNMRITEICNRYGFD
                     SLSHLAHFCKDSFGDTPRALRKKAANGEKIGKITD"
     CDS             5633..6337
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg32_5"
                     /sec_met_domain="SucD_FumR (E-value: 1.2e-131, bitscore:
                     425.5, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLSNSSVGRKVVMSVTGIALVLFLTFHMAMNLVAIISADGYNMI
                     CEFLGANWYALVATAALAALFIIHIIYAFWLTMQNRTARGSERYAVVDKPKTVEWASQN
                     MLVLGIIVIVGLGLHLFNFWAKMQLPELMHNLDMHADTLTLAYAANGAYHIQQTFSCPV
                     YVVLYLIWLFALWFHLTHGFWSSMQSLGWNNKVWINRWKCISNIYSTIVVLGFALVVVV
                     FFVKSLLCGGAC"
     CDS             6375..8354
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 200.6; E-value:
                     1.5e-61)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg32_6"
                     /sec_met_domain="FAD_binding_2 (E-value: 2.2e-62, bitscore:
                     200.6, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 4.8e-37,
                     bitscore: 116.1, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKIDSKIPEGPVAEKWTNYKAHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLGEMGFRVFNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTVKG
                     GDYRAREANVYRLAEVSNAIIDQCVAQGVPFAREYGGTLDNRSFGGAQVSRTFYAKGQT
                     GQQLLLGAYSALSRQVNVGTVKLFTRYEMQDVVIIDGRARGIIAKNLITGELERFAAHA
                     VVIATGGYGNAYFLSTNAMGCNCTAAISCYRKGAVFANPAYVQIHPTCIPVHGDKQSKL
                     TLMSESLRNDGRIWVPKKKEDAIKLQKGEIKGSDIPEEDRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNNTGLAVFLDFSEAINRLGIDVVLQRYGNLFDMYEEITDVNPGE
                     LAKEISGVKYYNPMMIYPAIHYTMGGIWVDYELQTTIKGLFAIGECNFSDHGANRLGAS
                     ALMQGLADGYFVLPYTIQNYLADQITVPRFSTDLPEFAEAEKAVQAKIDKFMSIQGKES
                     VDSIHKKLGHIMWEYVGMGRTAEGLKKGIAELKAVRKEFETNLFIPGSKEGMNVELDKA
                     IRLYDFITMGELVAYDALNRNESCGGHFREEYQTEEGEAKRDDENFFYVACWEYQGDDE
                     KAPVLIKEPLVYEAIKVQTRNYKS"
     CDS             8391..9146
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg32_7"
                     /sec_met_domain="Fer4_7 (E-value: 6.6e-13, bitscore: 38.5,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 4.7e-26, bitscore: 80.3,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.9e-07, bitscore: 20.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKNISFTLKVWRQAGPKAKGAFETYQMKDIPGDTSFLEMLDILN
                     EQLISERKEPVVFDHDCREGICGMCSLYINGHPHGPATGATTCQIYMRRFNDGDTITVE
                     PWRSAGFPVIKDLMVDRTAYDKIMQAGGYVSVRTGAPQDANAILIPKPIADEAMDAASC
                     IGCGACVAACKNGSAMLFVSAKVSQLNLLPQGKPEALRRAKAMLSKMDELGFGNCTNTR
                     ACEAECPKNISISNIARLNRDFIIAKLKD"
     CDS             complement(9273..10763)
                     /locus_tag="ctg32_8"
                     /transl_table=11
                     /translation="VYWLASSVCGVAQERPNIIVFLVDDMGLMDTSVPFIADESGQPVR
                     HPLNDWYHTPNMERLAKQGICFSTFYAQSVSSPSRASIMTGQNATRHGVTNWINAESNN
                     RNPFGPPQWNWKGLRKDMPTMPRVLQQAGYKTIHVGKAHFGCMGSEGENPLNIGFDVNI
                     AGSGIGHPGSYYGEWGYGHIKGQKIRAVPDLEKYHGTDTFLSEALTIEANREITKAVEE
                     KRPFYLNMAHYAVHSPFQADKRFLSRYTDPDKNEQARAFATLIEGMDKSLGDIMDQLEK
                     LGIAENTLILFLGDNGGDAPLGDERGYGSSAPLRGKKGTEFEGGMRVPFIAAWAKPEKK
                     SKVQKNLPIEVGSMQTQLGTIMDIYPTVLSVAGCEVPQNYVIDGFDLKKQLSGKVDKKR
                     PESFLMHFPHAHRGSYFTTYRMGDWKLIYYYLPETPKQPKALLYNLKDDPEERNELSSA
                     HPDKCREMIQEMSAQLEKEGALYPVDKQGNELKPFVYF"
     CDS             complement(11029..11871)
                     /locus_tag="ctg32_9"
                     /transl_table=11
                     /translation="MSSICQGTWDCQNCPKAVDNAIAHIIHPRGYHQPARKCEENFILF
                     LIRGEVLVNSQEYAGTMLRAGEFILQAIGSKFEMLAMTECECIYYRFIQPELFCDFRFN
                     HIMKEVSSPLIYSPLKIIPELKYFLDGSKSYLSESKVCRDLLSLKRKELAFVLGYYYSD
                     YDLASLVHPLSKYTSTFQYFILQNYKKVKTVEELAQLGGYTVSTLRRIFNNVFHEPVYE
                     WMQARRKEGILDELLNTNNSISEICYKYGFESLPHFSNFCKKFFGASPRMLRTNKKTI"
ORIGIN
        1 ggaaagcggc aagcatcagg catccggcac aggtatcgga ctggctttag tccgaaatct
       61 tgtagaactg cacgaaggcg aaatccgggt ggaaagcata cagaacgaag gaagtacttt
      121 ctatatcagc ttattaacag acaatatcta ccccaacgct ttgcatggag actctacgaa
      181 gcaaacagag gaggaaatga tatcagaagc tgttccggaa gattctcaaa atacggaacc
      241 ggaaacgagc aaacctatcc tgctgattgt agaagacaat gaagatatac agaaatacat
      301 cgccgaatct ttctccgact ctttcgaagt aatcacaggc agcaacggtg aggaagggaa
      361 acagcaggct ctcaaccgta ttcccgatat tatagtaagc gatatcatga tgccggtaat
      421 ggatggcatc acgctatgcc gtcaactaaa agaggatgtg cgtaccagcc acatccctgt
      481 catcctgcta acggccaaag attcattgca ggataaagaa gaaggatacg aagtgggagc
      541 ggattcttat ctgaccaagc ctttcagtgc ttcactgctg cgaagccgca tcaacaatct
      601 gctcgattcg agaaagaaac tgattgctca attccagcag accggaacga gtcataaccc
      661 caattctcat ttggatgaaa agcgttccat aatcaccgag gcgctcagca aactggataa
      721 cgaattcatt gagaaaatca cacaactggt tgaggataac ctttcttcgg aaaagatcga
      781 tatcacttac ctgtccgaca agatgtgtat gagcggctct acgctctacc ggaagatgaa
      841 agcgctgacc ggactttcta cgaacgaata catccggaaa gtaaaaatgc agaatgcgga
      901 acggttactc ctcgaaggaa aatataatat ctcggaaata gcctataaaa taggaatgaa
      961 cagtacaggc tacttccgtc aatgttttaa ggatgagttt ggtgtctctc cttcagatta
     1021 tctgaagcag ttcacctccc caactcctcc accatcgtct taaacaacga tctgctgtca
     1081 ttcagcggca tatccgtagc caagtcccag ctcatcattc ctttgagctg ctggtccatc
     1141 gcataacgtg tcttggcacg gatattattt tgcccgtcaa agacatacac gtctccttta
     1201 taggttactt cgttttgtgc cggccccgta atcagcccgt cctgcacaaa actgaagtaa
     1261 gcctcagtct tctttgagcc atcttttgtc acgccataga aaggaacgcc tgccaccagc
     1321 ttttcctttg gaatgccata agccaacgcc atctgtatat ccgaacagta tttctccatc
     1381 gggaagcgaa ccggcgaagg accgtaacac tgataagaaa tgaaatcgac cgcagcaatc
     1441 gcctctttac taatcttata acacacagga tgcagggata cgctgaacac atatttatct
     1501 cccaatacct ctctcatctt cagaatagcc agactgtaat cttcatactc tttttcagtc
     1561 tccgcccatt caaaatccag atcgatgcca tcgagcttat tcttttccag tatcttcttt
     1621 atgtttttgg caaatgcaac acgggccgcc tcatctgcaa ccatcgcttt ccactcgcca
     1681 ctggcagcgc ccagacgaag ttttgtcttt gttcctttca catccgcacg gacagacttt
     1741 atcaattcct cccaactagt cactcctttc ccattctcaa agatacgggg attctcaaac
     1801 gaaagcgacc catctttatt gggacggacg ttcagaaaaa tcagatcatc actcgccctt
     1861 aaactctcgg cagaaatacg tccgcgattg tagaaattac cccgtacata cgaactaatg
     1921 aagcagtttt gttgcgcata caacgataat ccgacaaaca agagaaggaa aaatacaatt
     1981 tttcttggta gtagcataat aattgataat taatgggttt tgatcgcaaa agtaggtaca
     2041 ggcaaagaaa acaaatgttc aaaaatcact ataatacttc caaaaatcaa cataaagttt
     2101 cttattgaga gatgtaaaac aaaaacatcc ttttaaaaag ggaattaagt gttttaccgg
     2161 aatcaattac attaaatcgc aaaagttttc cggattataa tacaaagtga ataacaatca
     2221 ctatctttag gcataaaatc agttcatatg atcatttatc tacatgaaag caaccgtcta
     2281 acttagactg acttttgaag aaatgcaaca tctatacgta tatgaataaa ctcgtactta
     2341 ccggtctgct ggcagccgga accatgacgc acctgcaagg cgctcaacct gccggacaac
     2401 gccccaacat cctttttatc ctgagtgacg accacacctc ccaagcctgg ggcatctatg
     2461 gcggagtact ggcagaatat gcccacaacg ccaacatccg ccggctggca aaagaagggg
     2521 tagtgctcga caactgtttc tgcaccaact ctatctcagc acccagccgt gccagtatcc
     2581 tcaccggtct atacagtcac cggaacagac tgtacaccct tgcggactca ctggacacct
     2641 ccatccccac ccttgccacc ctgctacaag ccaacggata ccacaccgga ctcgtcggca
     2701 aatggcatat ccagtcgcaa ccgcaaggat tcgactacta ctccatcttc tacgatcaag
     2761 gcgaataccg tgacccgact ttcatagaga gcaccgaccc gtggcccggc aaccaccagt
     2821 tcggcgaacg ggtgctcggc ttctccaccg acctcgtcac cgagaaagcc atccgatgga
     2881 tgaaagagca ggacggcaat caacccttcc tgatgtgctg ccatttcaaa gcaacgcacg
     2941 aaccctacga ctacccgata cgcatggagc atctctacga cggcgtcacc ttccccgaac
     3001 ccgaaaacct gctggactgg ggaccggaaa ccaacggccg ttctttcaaa ggacagacac
     3061 tggaagaact ggaacgccgc tggcgcatcg catcacagga tcccgacaag tggtggtgcc
     3121 gctaccccgg actgccgttc agcaccgaag ggatgcaacg gacagccgcc agacgtgctt
     3181 cctaccaaaa gtttatccgt gactacctcc gttgtggcgc taccgtcgac gacaacatcg
     3241 gcaaactcct gaaagctctg gacgaaatga atatcgccga caataccatc gtcatctacg
     3301 tctccgacca aggctatttc ctaggcgaac acggcttctt cgacaaacgg atgttttatg
     3361 aagaatcggc tcgtatgcct ttcgttatcc gttatccgaa taaggtcccc gcaggaaaac
     3421 gtctggatga tctgatactg aatgtcgatt tcgcaccgac gctggcagaa tttgccggag
     3481 taaagatgga gaatgtgcaa ggagacagct tcgtcagcaa cctggaaggc aacacgccga
     3541 ccgactggcg aaaagaaatc tactatcgct actggaccaa tcacgctatt cgtcccgcac
     3601 acttcgccat ccggtcagac cgctacaagc tgatcttcta ttatgcccga aatctggaca
     3661 tgactgatac ggagaacttc gactttactc cgtcatggga cttctatgac ttgcagaacg
     3721 atccgcacga gaatcataat gcatacaacg atccgaaata tgcacctgtc atcaaacaga
     3781 tgaagaagga cttattgaga cttcgcaaag aaaccggaga tacggacggg aaatatccgg
     3841 aaatgcagga actgcttgaa aaatactata ataagtaagt gactggtacg gaaactgaac
     3901 tgtcgcattt ataacttgaa cttaggcagc tgctacaagt gaaaaagata gcagttttgc
     3961 cctaacgctc tcattattcg cgtgtatccc tttattcatc ggcatttcaa gcattacagc
     4021 aagtatggtg gcagagtgag agcaaaggtt tgctctcact ctgccaccac ggcatatagg
     4081 tcgtttatcc tacattatac tttgatttac tgggtattaa catctgacgc gtcagctatt
     4141 aacgattgtc atgtcagcta ttaataattg agaaatcagg tattaacagc tgagaagtca
     4201 tccattattg actgaaaaat gaaataatac ctttcgaacg gacaggtcaa tcagagcaac
     4261 ttatgcggtc aagtgagttg aatcgagctg tcatatgaac gaaatcgaca gttgttccaa
     4321 gaagtttcat tacttgaaac agtttgtttc atgccttgaa acacttggtt tcaacaggtg
     4381 gaactaatga tgaaactact tgttctgaat atatcatgta aagggatgaa gaaaatgctg
     4441 cagatggcag ataaaaatgt attaatgtat taaagaacgc cattcaggag tccgtgaaac
     4501 ttcaaagttg tgcaaacaaa accaataaag acaatcatat ccccgtttct gctaaaacat
     4561 aatggaagaa agaattttat tttcacaaaa aacgactatc tttgtccctg tagacaacga
     4621 ttcacggata aaacccatgt caaaagactc actttgtgct caacatacag attgctcagg
     4681 atgccccaaa gcgatggaaa gtactcttat tcacagaaat ctgctcagag ggcagcatat
     4741 tccgaaggat aagtgcacgc aaaactgcat gctctttatg atcgagggcg aattgctgat
     4801 caacagtgac gaacatcccg gaacgacact acacgagaaa cagtttatcc tgcaagccat
     4861 cggctcaaaa tacgagatac tggcactgac ggacgtatca tacatccttt tctggttcaa
     4921 cgaactgccg ttgctatgcg aaaaccgcta ccgtgaaatc atcgaccagg cagaaggccc
     4981 gctgacctac accccaatgg tgatgaaccc gcgcctgttc tatctcatca acgacgtagc
     5041 cgcatacctt gacgaatcga cacccgcctg cggcaaatat atcgacctga aatgtcagga
     5101 gatggtgtat atgatcacca attactatcc cctgccccag ttgagggctt tcttctaccc
     5161 gatcagcacc tatacggaaa gtttccaata ctttgtcatg cagaattaca gcaaagcgaa
     5221 gaacgtcgaa gaattcgcac atctgggagg ctataacacc accaccttcc gccgtctctt
     5281 ccgaaactta tacggcgtgc ccgtctacga atggatgctg gagaaaaaac gggaaggcat
     5341 cctcgaagac ctacagcact ctaatatgcg gattacagag atttgcaacc ggtatggttt
     5401 cgactcgctg tcccaccttg cacacttctg caaagactcc ttcggagaca ccccgcgcgc
     5461 cttgcgcaag aaagcggcca atggcgaaaa aatcggaaag atcaccgatt aaggaattat
     5521 ttctttaatt ctttggtcaa tcaatctatt tcccctattt ttgcagtctg taagaggtgt
     5581 aaaacgtcga aattttagtt ctaacaatta aataatttaa attcaatcat ttatgtggtt
     5641 aagtaattca tctgtaggaa ggaaagtggt gatgagcgtt accggtatcg cccttgtcct
     5701 gtttctaaca tttcacatgg cgatgaactt agttgcaatc atctcggctg atggttacaa
     5761 catgatttgt gagtttttgg gagcaaactg gtatgcgctg gtagctaccg cagcactggc
     5821 tgctcttttc attattcaca tcatctacgc gttctggctg acaatgcaga atcgcacagc
     5881 gcgcggtagc gaacgctatg cagtagtcga caaaccgaaa actgtagagt gggcttctca
     5941 aaacatgttg gtgttaggca ttatcgttat cgtaggcctc ggtttgcacc tcttcaactt
     6001 ctgggcaaaa atgcagttgc cggaactgat gcacaacctg gacatgcacg ctgatacact
     6061 gacgctggct tatgcggcaa acggtgcata tcacatccag cagacattct cttgtccggt
     6121 ttatgtagtg ctctacctca tttggctgtt tgctctgtgg ttccacctga ctcacggttt
     6181 ctggagctcc atgcaatcac tgggatggaa caacaaggta tggatcaatc gttggaaatg
     6241 tatttctaac atctattcta cgattgtagt actcggtttc gcactcgtag tagtggtatt
     6301 cttcgtgaaa tcactccttt gtggcggtgc ttgctaaata gtaaattgta aatgattaaa
     6361 ttgtaaataa tattatgatc aagatagatt caaaaattcc agaaggcccg gtggctgaga
     6421 aatggaccaa ctataaagct caccagaaat tggtgaaccc cgctaataaa cgccgtttgg
     6481 atatcatcgt tgtgggtacg ggtctggcag gtgcttctgc tgctgcatcc ctcggtgaaa
     6541 tgggtttcag agtattcaac ttctgtattc aggactctcc gcgccgtgca cactctatcg
     6601 ctgcacaggg tggtatcaat gctgcaaaga attatcagaa tgatggtgac tccgtttacc
     6661 gtctgtttta cgatacagta aaaggtggtg actatcgtgc acgtgaagcc aacgtttacc
     6721 gtctggccga agtgtccaac gctatcatcg accaatgcgt ggcacaaggt gttcctttcg
     6781 cacgcgaata cggcggtaca ctggacaacc gttcttttgg tggtgcacag gtatcacgta
     6841 cgttctacgc taaaggccag accggtcagc agctgttgct gggtgcttac tccgcactaa
     6901 gccgtcaggt aaacgtaggt acggtgaagt tgttcacccg ttatgaaatg caggacgttg
     6961 taatcatcga cggacgtgct cgcggtatca tcgccaagaa cttaatcacc ggcgaactgg
     7021 aacgtttcgc tgctcacgcc gtagtaatcg ctaccggtgg ttacggtaac gcttacttcc
     7081 tgtctaccaa cgctatgggt tgtaactgta cagctgctat ctcttgctac cgcaagggtg
     7141 ctgtattcgc taaccccgca tacgttcaga ttcacccgac ttgtatcccg gtacacggtg
     7201 acaagcagtc caaactgact ctgatgtccg aatctctgcg taacgacggt cgtatctggg
     7261 ttccgaagaa gaaagaagac gctatcaaat tgcagaaagg cgaaatcaag ggaagcgata
     7321 ttcctgaaga agaccgcgac tattatctgg aacgccgtta tccggcattc ggtaacctgg
     7381 ttccacgtga cgttgccagt cgtgcagcta aagaacgttg cgacgcaggt ttcggtgtga
     7441 acaacacagg tctggccgta ttcctcgatt tctctgaagc tatcaaccgc ctgggcatcg
     7501 atgtagtgct tcagcgttat ggtaacctct tcgatatgta tgaagaaatc actgacgtta
     7561 atccgggcga actggcaaaa gaaatcagtg gtgtgaaata ttataatccg atgatgattt
     7621 atccggctat ccactacaca atgggtggta tctgggtaga ctacgaactg cagactacca
     7681 tcaagggtct gttcgctatc ggtgaatgta acttctccga ccacggtgca aaccgcctcg
     7741 gtgcttccgc attgatgcaa ggtctggccg acggttactt cgtattgcct tacactatcc
     7801 agaactatct ggcagatcag attactgttc ctcgtttctc tactgacctt ccggaatttg
     7861 ccgaagcaga aaaggcagtt caggctaaga tcgacaagtt catgagcatc cagggtaaag
     7921 aatcagttga ttctatccac aagaaactgg gtcacatcat gtgggaatac gtaggtatgg
     7981 gacgtacggc agaaggcctg aagaaaggta tcgccgaact gaaagcagtc cgcaaggaat
     8041 tcgaaaccaa tctgtttatc cccggttcta aggaaggtat gaacgttgag ctcgacaagg
     8101 ctatccgtct gtatgacttc atcactatgg gcgagctcgt tgcttacgac gcattgaacc
     8161 gtaacgaaag ttgtggtggt cacttccgtg aagaatacca gactgaagaa ggagaagcaa
     8221 aacgtgatga cgaaaacttc ttctacgtag cttgctggga atatcagggt gacgatgaaa
     8281 aggctcctgt attgatcaaa gaaccgctgg tatacgaagc tatcaaggtt cagacccgta
     8341 actacaagag ctaatcggtg aagttaaaca tttaaaagaa ttagaagaaa atggataaaa
     8401 atatatcatt tacactgaag gtatggcgtc aagcaggccc gaaggctaaa ggcgcttttg
     8461 aaacctacca aatgaaagat atccccggtg atacttcctt cctcgaaatg ctggatattc
     8521 tgaacgaaca gctgatcagc gaaagaaaag aaccggttgt attcgaccac gactgccgcg
     8581 aaggtatctg cggtatgtgt tctctttaca tcaacggaca tccgcacggt cctgcaacag
     8641 gtgctactac ttgccagatt tacatgcgtc gtttcaacga tggtgacacc atcactgttg
     8701 agccttggcg ttcggccggt ttccctgtca tcaaggactt gatggtagac cgtactgctt
     8761 atgacaagat catgcaggcc ggtggttacg taagcgttcg tacaggtgct ccgcaggatg
     8821 ccaacgctat cctgatcccg aagcccattg ctgacgaagc tatggatgcc gcttcttgta
     8881 tcggttgcgg tgcttgtgta gctgcttgta agaatggttc tgccatgttg ttcgtttcgg
     8941 caaaggtcag ccagttgaac ttgcttccgc aaggtaaacc ggaagctctg cgccgtgcga
     9001 aagctatgtt gtccaagatg gacgaactcg gattcggtaa ctgtaccaac acccgcgctt
     9061 gcgaggctga atgtccgaag aacatctcta tcagcaacat cgcccgcctg aaccgcgact
     9121 tcatcatcgc taaactgaaa gactaagcgt gagcttgatt tgattaatag cataaatccc
     9181 ccgtcggcgt tagctggcgg gggatttctt tttactgacc aattactaat ggattaactg
     9241 ttattattca ttccgaccta aatcgacatt tatcaaaagt aaacaaaagg tttcaactca
     9301 tttccttgtt tatccaccgg ataaagagct ccttccttct ctaattgagc agacatttcc
     9361 tgaatcatct ccctgcattt atccggatgt gcggaggaaa gttcatttct ttcttccgga
     9421 tcatctttca gattgtaaag caaagctttg ggttgcttcg gagtctcggg aagataataa
     9481 taaatcagtt tccagtcgcc catgcgatag gtggtgaagt agctgccgcg gtgtgcatga
     9541 gggaagtgca tcaggaaaga ctcgggacgc ttcttgtcca ccttaccgct cagttgcttt
     9601 ttcagatcga acccgtctat cacgtagttt tggggaactt cacatcctgc cacagacaga
     9661 accgtcggat agatatccat gattgtaccc aactgtgtct gcatacttcc tacttcaata
     9721 ggcaagttct tctgtacttt gctcttcttc tcaggctttg cccaagctgc gatgaaagga
     9781 acacgcatac caccttcaaa ctccgtcccc tttttacctc tcagcggagc ggaagaacca
     9841 tagccacgtt catctcccaa tggagcatca ccaccgttat ctcctaaaaa gagaatcagc
     9901 gtattctcag caattcccag cttttcgagt tggtccatga tgtcgcctaa tgatttatcc
     9961 atgccttcta tcaatgtagc aaaagctctt gcctgctcgt tcttatccgg gtcggtgtag
    10021 cgtgacaaga aacgtttgtc tgcctggaaa ggtgaatgaa ctgcgtaatg ggccatattc
    10081 agatagaaag gtcgtttttc ttctacggct ttggtgatct cccgattcgc ttctatagtc
    10141 agcgcttcac tcaggaaggt atctgtaccg tgatatttct ccaggtcagg aactgctcta
    10201 atcttctgtc ccttgatatg cccgtatccc cattcgccat aatagctgcc gggatgtcca
    10261 atgccggaac ctgcgatatt tacatcaaag ccgatattca gcggattctc tccttcgctt
    10321 cccatacagc cgaaatgtgc ttttcctaca tgaatggttt tatatccggc ttgttgcagg
    10381 actctcggca tggtaggcat atcttttctg agacctttcc agttccattg gggcggtccg
    10441 aaaggattcc ggttgttgct ctcggcatta atccagttag tgactccatg cctggtcgca
    10501 ttctgtccgg tcatgatgga agctctggaa ggggaactca cgctctgtgc gtaaaaagta
    10561 gagaaacaaa taccctgttt agccagtctc tccatattcg gagtatgata ccagtcattc
    10621 agcggatgac gcaccggctg accgctctca tctgcgataa aaggaaccga cgtatccata
    10681 agtcccatgt catctacaag gaagacaata atattcgggc gttcctgagc caccccgcaa
    10741 acggaagatg ccaaccaata cacaaaattc cttaaaagct cgttttgttc tcattacata
    10801 gtatttatga tttatatcct agttattgta cgtgtcgcaa tagatttaaa tttactgaaa
    10861 taaaaagttt aatttccgta tccgccttgt catggcttta tttgaagtga tccgactcta
    10921 taataaagat gtattagact gattttaagg gaaacagcag caatatacaa caaatgcact
    10981 atgctcacaa agaaaaaaag attatttgac gttctctctg aaaaattatc agatggtctt
    11041 tttgtttgtt cttagcatgc gtggagaagc accaaagaat ttcttacaga aattggagaa
    11101 gtgtggcaga gattcaaagc catatttata gcatatttca gagatactgt tgtttgtatt
    11161 aagcaactcg tccaaaatac cttccttacg tcgcgcctgc atccattcgt ataccggttc
    11221 gtggaataca ttattgaaga tacgccgcag ggtactgaca gtatagccgc caagttgggc
    11281 aagttcttcc actgttttta ctttcttata gttttgaagg atgaagtact ggaaagtgga
    11341 agtgtattta gagagtggat gtaccaagct tgccaaatca tagtctgaat aatagtaccc
    11401 caatacaaat gccagttcct tgcgctttaa cgacagcaag tcccgacaaa ctttactttc
    11461 actcaaatag gatttagagc catccaaaaa atatttcaat tcagggatta tctttaatgg
    11521 tgaatagatt aatggtgaag acacctcctt cataatatga ttgaaacgga agtcacagaa
    11581 tagttccggc tgaatgaaac gataataaat acattcgcac tcagtcatgg caagcatctc
    11641 aaattttgaa ccgatagcct gaagaataaa ttcacctgct ctcagcatcg tacctgcata
    11701 ttcttgacta ttaaccaata cctcacctct tatcaaaaaa aggatgaagt tttcctcaca
    11761 tttccgggct ggttggtgat agcctcttgg atgaataatg tgagcaatag cattgtctac
    11821 ggctttcggg cagttctgac aatcccaagt accttgacag atagatgaca tatatttgtg
    11881 ttggtgtttg atttgttcct gttggcaaca aaaatatatg aaatctttta catggcaata
    11941 gaaaaggagg agaaaagtgc aaaagagatg attcgaaaag aatatttaaa gcttatttat
    12001 caagatgaaa aactttcaaa attaataaaa caataagata taaatactga ggaaataata
    12061 taaatcttga attacgtata atacatatat cttaagatag agaatcctag ttttttgttt
    12121 aaaaactagg attcatagaa atatcacatt ttcaccattt a
//
