LOCUS       gnlProkkaBODOENPF_27   15320 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BODOENPF_27.
ACCESSION   gnlProkkaBODOENPF_27
VERSION     gnlProkkaBODOENPF_27
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 22:23:33
            Original ID  :: gnl|Prokka|BODOENPF_27
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 65370
            Orig. end    :: 80690
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15320
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:10351]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10351
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..15320
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15320
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(332..997)
                     /locus_tag="ctg27_57"
                     /transl_table=11
                     /translation="MFEIKVSKEIKDACPVFAGAAVYAVVKNTAYSEGLWQEIDAFTRQ
                     LTSTTQMEDIKHQPVIFATREAYKRCGKDPGRYRPSAEALRRRLMRGIPLYQIDTLVDL
                     INLVSLRTGHSIGGFDADKIQGTHLELGIGKAGEPFEGIGRGVLNIEGLPVYRDSFGGI
                     GTPTSDHERTKMDLGTTHILAIVNGYNGKEGLQEAVEMIQTLLRNYTESDGGEIVFFE"
     CDS             complement(1048..1860)
                     /locus_tag="ctg27_58"
                     /transl_table=11
                     /translation="MISLTKHNELKGYKSLEAYPEVAHFVTTRHEGISTGAYGSFNCSP
                     YTNDSCMNVNRNQSWLFQCMNHQIKELFIPEQSHGCASLIINESFFKESLEMRRLLLRG
                     MDALITNVPGYCVCVTTADCVPVLLYDKKQHVVAAVHAGWKGTVKHIVSNVMDHLNKMF
                     GTQGEDVIACIGPSISLESFEVGDEVYDAFEESGFDMSLISMKKKETGKYHIDLWEANR
                     IELLNLGVPAEQIEVAGICTYIHHDEFFSARRLGIDSGRTLSGIMIRK"
     CDS             complement(1857..3020)
                     /locus_tag="ctg27_59"
                     /transl_table=11
                     /translation="MAESNFVDYVKIYCRSGKGGRGSTHMRREKYCPNGGPDGGDGGRG
                     GHIILRGNRNYWTLLHLKYDRHAMAGHGESGSKGRSFGKDGADKIIEVPCGTVVYNAET
                     GEYLCDVTEDGQEVVLLKGGRGGQGNWHFKTATRQAPRFAQPGEPMQEMTVIMELKLLA
                     DVGLVGFPNAGKSTLLSSISAAKPKIADYPFTTLEPNLGIVSYHGGKSFVMADIPGIIE
                     GASQGKGLGLRFLRHIERNSLLLFMVPADSDDIRKEYEVLLNELRTFNPEMLDKQRVLA
                     VTKSDMLDQELMDEIEPTLPEGIPHVFISSVSGLGISVLKDILWEELNKESNKIEDIVH
                     RPKDVTRLQQELKDMGEDEDIVYEYEEDVDDDDDIDYEYEEEDWEEK"
     CDS             complement(3110..3679)
                     /locus_tag="ctg27_60"
                     /transl_table=11
                     /translation="MLNIVIFGAPGSGKGTQSERIVEKYGINHISTGDVLRAEIKNGTE
                     LGKTAKGYIDQGQLIPDELMIDILASVFDSFKDSKGVIFDGFPRTIAQAEALKKMLAER
                     GQDVSVMVDLDVPEEELMVRLIKRGKDSGRADDNEETIKKRLHVYHSQTAPLIDWYKNE
                     KKYQHINGLGTMEGIFAEICEAVDKL"
     CDS             complement(3739..4275)
                     /locus_tag="ctg27_61"
                     /transl_table=11
                     /translation="MDTIQIKDKLFTVSIKEQEIQKEVIRVANEINRDLAGKNPLFLSV
                     LNGSFMFTADLLKHITIPCEISFVKLASYQGITSTGVIKEVIGLNEDIAGRTIVIVEDI
                     VDTGLTMQRLLETLGTRNPEAIHIASLLVKPEKLKVNLNIEYVAMEIPNDFIVGYGLDY
                     DGFGRNYPDIYTVVD"
     CDS             complement(4316..5860)
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 46.8; E-value: 2.5e-14)"
                     /gene_kind="transport"
                     /locus_tag="ctg27_62"
                     /transl_table=11
                     /translation="MSALKGHPKGLYLIFATSTAERFSYYGMRAIFILFLTQALLFDKE
                     AAASIYGSYTGLVYLTPLIGGYIADKYWGIRRSVFWGAVMMAVGQFLMFMSASTLDNTN
                     LAHWMMYGGLGFLILGNGCFKPTVSSLVGQLYEPGDRRLDAAYTIFYMGVNVGSFAAPL
                     ICGYLGDTGDPHDFKWGFLAAGIMTLFTVVLFETQKNKYLFSPSGEPIGIIPDAKREKK
                     EDKADHISHPKMDKRTKVRNTLVITILTIALIAFFNYAFEGDWVSIGIFTACIVFPVLI
                     LLDGSLTKIERSRIFVIYIVAFFVIFFWAAYEQAGASLTLFASEQTNRDIFGWEMPASW
                     FQSFNPLFVVVLAYIMPGVWGFLNKRKMEPASPTKQAIGLLLLSLGYLFICFGVKDAVP
                     GVKVSMIWLTGLYFIHTMGEIALSPIGLSMVNKLSPLRFASLMMGIWYLSTATANKFAG
                     MLSGLYPEAGKVKSIFGYQIATMYDFFMVFVVMSGVASLILFLLSKKLQKMMHGVE"
     CDS             complement(6054..6278)
                     /locus_tag="ctg27_63"
                     /transl_table=11
                     /translation="MMEKTKIGLNAGKVWRILNEKGELSMFDLCRELSLTFEDVALAIG
                     WLAREDKIFLRKREGMLFASIENVEFTFG"
     CDS             7010..8521
                     /locus_tag="ctg27_64"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIENEPIASIDLMERAATVLTKAITDRWNT
                     ETPVTIFAGPGNNGGDALAVARMMAEKGYKIEVFLFNTKGELSPDCQTNKELVEMMEEV
                     KFHEISTQFVPPALTPDHLVIDGLFGSGLNKPLSGGFAAVVKYINSSPAMVVAIDIPSG
                     LMGEENTFNVKANIIRADVTFSLQLPKLAFLFAENTEFVGEWEVLDIQLSEDGIEEMET
                     NYEMLEIEQIRSLIKPRKQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPMCNNDILQTSIPEAIVETDINETCFAVPTDTDDYQAVGIGPGLGRNEETEAALLEQ
                     LEHCQTPVVVDADALNILANHRHALTHLPKGSILTPHPKELERLTGKCQDSYERLMKAC
                     ELARAAHVHIILKGAYSAIITPEGKCFFNPTGNPGMATGGSGDVLTGVILALLAQGYPT
                     EEAAKIGTYIHGLAGDVAQKKQGMIGMIASDIITCLPTAWRLVSE"
     CDS             8594..9661
                     /locus_tag="ctg27_65"
                     /transl_table=11
                     /translation="MKKLIIAAGLLMTTSAYAQTEVLTGVTRGKDYGVVYSLPKTQIEL
                     EIKANKVNYTPGEFSKYADRYLRLTNVSADPEEYWELASVKVKSVGVPNSETMYFVKLK
                     DKTVAPLMELTEDGIVKTINVPYSNSSVGKKAAPAPAVLQKKANPREFLTEEILMASST
                     AKMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNAQEEAMTQMFSGTCN
                     KEERTFTVRLTPDKEFNNEVAFRFSKKLGVVANNDLAGTPFYISLKDLKSVKIPQEDGK
                     KKKDLDGIAYNVPGQAMVTLTDGKKKLYEGELPITQFGVIEYLAPVLFNKNSTIKVYFD
                     PNTGGLLKVDREEGK"
     CDS             9698..9982
                     /locus_tag="ctg27_66"
                     /transl_table=11
                     /translation="MVGEGHAFDMIRRIKEGREASRLRRERANDKLKHLNRANEPYPLP
                     NTTPEEMERIIHDSEKKKEKDSNYFVWGTLIIMGVLIAIAVILWAVFIK"
     CDS             complement(10001..10351)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg27_67"
                     /sec_met_domain="PqqD_RRE (E-value: 5.5e-11, bitscore:
                     34.4, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 2e-17, bitscore: 55.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAKEKINLLEVIPCRSEHITAEREGETIVLSFPRFKYPWMQRFL
                     VPKGMSKELHVKLEEHGTAVWELIDGKRNVREIIEKLADHFQNEEGYESRVSAYLSQMQ
                     KDGFIKLVIPVV"
     CDS             complement(10449..11837)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 92.9; E-value: 2.7e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg27_68"
                     /transl_table=11
                     /translation="MTEHLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AISTTFPEGAMLFGFKTQVTLAALGYAIFGVGVEIASITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGTFHTNIPAPILFCLIMLCVGTIAFFLYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMIIGSVMLIFVHTMFAL
                     PILNIWWFATIIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNTYCKGPVVDGAQTYDYTLPMAIFALFGVLALIVALMLKAENKKKGYGLEEA
                     NIQK"
     CDS             complement(12087..12482)
                     /locus_tag="ctg27_69"
                     /transl_table=11
                     /translation="MYLLFVILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSIATAYVVPRSAVAKDAVLEQAQKEQQTNPYNLPAGTAAP
                     QTEAPATNAPATETPAPATETPAPAAE"
     CDS             complement(12489..13262)
                     /locus_tag="ctg27_70"
                     /transl_table=11
                     /translation="MTSVNFQQWIQHPETLNRDTLYELRNLLARYPYFQSLRLLYLKNL
                     YILHDISFGGELRKAVLYIADRRQLFRLIEGDRYDVQARKKGVPLTEVLKDEPSVDRTL
                     ALIDAFLSTVPEEVTARTSFDYSMDYTSYLLEETPATEQPAEETPKLKGYELIDDFIEK
                     SESDSPLCKKPLREEMPSSPTSSDELTEEETMKEEEEDDSCFTETLAKIYVKQQRYSKA
                     LEIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
     CDS             complement(13268..13795)
                     /locus_tag="ctg27_71"
                     /transl_table=11
                     /translation="MNWIKKIIRPLLLFGLPLVVIACTVSYKFNGSSINYDKVKTISIA
                     DFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPNQNADLQIDGEITGYNQYNQAVS
                     ADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTYDSSQLLTAVQDGLIAEMSKEI
                     TDQIFNATVANW"
     CDS             complement(13782..15023)
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 390.2; E-value:
                     2.3e-118)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg27_72"
                     /transl_table=11
                     /translation="MTKAEIQQVKQRFGIIGNTEALSRAIDVAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EADGGTIFLDEVGELPMSTQARLLRVLESGEFMKVGSSKVQKTDVRVVAATNVNLTQAI
                     AEGRFREDLYYRLNTVPIQIPPLRERGDDVLLLFRKFSADFAEKYRMPAIQLTEDAKKE
                     LLAYPWPGNVRQLKNITEQISIIETNREISAAILQNYLPAQNTQRLPALMGTRESKGFE
                     SEREILYSVLFDMRQEVAELKKMVHNLMAERAGQVGQVGQMGTVVTTPVVTAHQPSVPA
                     IIHTMQPTVCKDDDDIQDTEEYVEESPLSLDEVEKEMIRKALERHHGKRKSAAKDLNIS
                     ERTLYRKIKEYELD"
     CDS             15234..15320
                     /locus_tag="ctg27_73"
                     /transl_table=11
                     /translation="MSACIIMIKKYTLIKLENEYLELQILPED"
ORIGIN
        1 catacgcacc actccatcaa aagcagcacg aatcgtatct tttgcacaag tcttaatgtc
       61 tgttcccgaa tgtcctccgc gagttccata ggcagagatt acttttcctc cgggtaatgg
      121 gaaagcatat tcgtgatctt tcagagagtc caaatgcaga tagatatgat tgcttttagc
      181 aaataatccg ggagtagcta cccgtacatc agccatttcg cgggcagaga aggaaggttt
      241 atcctgcccg tcggcagtca gtggcaataa taaaactgtc agtaagataa gtatgttttt
      301 catgtctttt ttcttagagc actcattcta attattcgaa gaatacgatt tcgcctccat
      361 ccgattctgt atagtttctt aataaggtct gtatcatttc aacagcttct tgcaaacctt
      421 cttttccgtt ataaccattg actatggcta ggatatgagt ggttccgaga tccattttcg
      481 tacgttcatg atcgcttgtc ggggttccga ttcctccaaa agaatcacga tatacaggta
      541 atccttcgat attcaatacc ccgcgtccga taccttcaaa cggttctcct gctttgccga
      601 taccgagttc aagatgcgta ccttgtattt tgtccgcgtc aaaaccaccg atcgaatgtc
      661 ccgtacgaag agacactaaa ttaataaggt ctaccaacgt atcaatctga tataaaggaa
      721 ttccacgcat caggcggcgg cgtagagctt cggctgacgg acgataacgt ccggggtctt
      781 tgccacaacg tttataagcc tcacgggtag caaagataac gggttgatgt ttgatgtctt
      841 ccatctgtgt tgtggaagtc agttgcctag taaaagcgtc gatttcctgc caaagccctt
      901 cgctgtaagc tgtatttttc acaacagcat acacagcggc tccggcaaaa accgggcatg
      961 cgtcttttat ttctttagat acttttattt caaacataac ttatcataaa ccaatcatca
     1021 gcgtcctgca ataacggaca ccaattatta ctttctaatc attattcccg acaatgtacg
     1081 accggaatct attcccagtc tacgtgcaga gaagaattca tcatgatgaa tataggtaca
     1141 gattccggcc acttctatct gttctgcagg cactccgaga ttcagtaatt caatccggtt
     1201 ggcttcccac aaatcaatat gatatttgcc tgtctccttc ttcttcatag aaataagaga
     1261 catatcgaag ccgctttctt caaaagcatc atacacctca tcacctactt caaatgattc
     1321 gagcgaaatg ctcggcccga tgcaagctat cacatcttca ccttgcgtcc cgaacatctt
     1381 attcaagtga tccatcacat tactgacaat atgcttcacc gttcctttcc atccggcatg
     1441 aacggcagcc acaacgtgtt gttttttgtc gtacagcaat acaggaacac aatccgccgt
     1501 cgtgacacaa acgcaatatc ccggcacatt agttatcaag gcatccattc ctcgcagaag
     1561 tagccgtctc atttccaatg attctttaaa aaatgattca ttgataatca gactggcaca
     1621 accatgactc tgttcaggaa taaataattc ttttatctga tgattcatgc actgaaacaa
     1681 ccagctctga ttgcgattga cgttcataca tgagtcgttg gtataaggcg aacagttgaa
     1741 agagccgtaa gctccggtgc ttataccttc gtgacgcgta gttacaaaat gagctacttc
     1801 gggatatgcc tccagtgact tatatccctt caactcgtta tgttttgtaa gtgaaatcat
     1861 ttttcttccc aatcttcttc ttcgtattca taatcgatat catcgtcatc gtcgacatct
     1921 tcctcatatt cataaacgat gtcttcatct tcgcccatgt ctttgagttc ctgttgcaga
     1981 cgggtcacgt ctttcggacg gtgaacgatg tcctctatct tattgctttc cttgttcagt
     2041 tcttcccaaa ggatgtcttt caacaccgag atgcccaaac cggaaacaga agatatgaat
     2101 acatgtggaa tgccttccgg caatgtaggt tcaatctcgt ccatcaactc ctgatcgagc
     2161 atatcactct tggtgacagc caacacacgt tgcttgtcca acatttcagg attgaaggta
     2221 cgcagttcgt tcagcaagac ttcgtattct ttacgaatgt cgtcgctgtc tgccggaacc
     2281 ataaacagca gtaatgaatt acgctcgata tgacgtaaga aacgcagtcc caaacctttc
     2341 ccctggctag caccttcgat aatacccggt atgtccgcca tcacaaagga ttttccaccg
     2401 tgataggaaa cgatgcccaa gttgggttcg agtgtagtaa acgggtaatc ggcaattttc
     2461 ggtttggcag ccgaaatgga agaaagcaaa gttgactttc ccgcattcgg gaaacctacc
     2521 agaccgacat cggcaagcag tttcagctcc atgataacgg tcatttcctg catcggctct
     2581 cccggctgcg caaaacgcgg agcctgacgg gtggccgtct tgaaatgcca gttaccctga
     2641 ccgccgcggc cgcctttgag caagaccact tcctgtccgt cttctgttac gtcacaaaga
     2701 tactcccctg tctcggcatt ataaactacc gttccgcagg gtacttctat tattttatcc
     2761 gcaccgtctt ttccgaagct acgtcctttg ctccccgatt caccatgacc ggccattgca
     2821 tgacggtcat acttcaagtg cagcaatgtc cagtaattac ggttaccgcg caagatgata
     2881 tgacctcctc ttccaccatc gcccccgtcg ggacctccgt taggacaata tttctcgcgc
     2941 ctcatgtgcg tagagcctct tccgcccttg cccgagcgac agtatatctt tacgtaatca
     3001 acaaaattcg attcagccat atttttttaa agagttaaag tagtcagtag ttagagcagt
     3061 taattagaac actccggcta ctgacttatt tatttataat attgtattat tacaatttat
     3121 ctactgcttc gcagatttca gcgaagatac cttccatagt acccaagccg ttgatgtgtt
     3181 ggtatttctt ttcgttcttg taccagtcga tcagtggagc agtctgtgaa tgatatacgt
     3241 gcagacgttt tttgattgtc tcttcgttat catcagcacg accggaatcc ttgccacgtt
     3301 taatgagacg taccatcagt tcttcttccg gaacatccag gtcaaccata acagaaacgt
     3361 cctgtcctct ttctgccaac attttcttta atgcttctgc ctgtgcaatt gttcttggga
     3421 aaccgtcgaa aattacccct ttactatctt tgaagctgtc gaatacgctt gccagaatat
     3481 caatcattaa ttcatcagga atcaattgac cttggtcgat gtaaccttta gctgttttac
     3541 ccagttctgt gccattcttg atttcagcac gcaatacatc tcctgtcgag atgtgattga
     3601 ttccatactt ttctacgata cgttcgctct gtgttccttt tcctgaaccc ggagcaccga
     3661 aaattacgat gttcaacatt ttgttattta caatttaacg atttactatt taccatttaa
     3721 actggtacct atttaatatt aatctactac tgtataaata tcgggataat tacgtccgaa
     3781 accatcataa tccagtccgt aacctacgat aaagtcgttc gggatttcca tcgctacata
     3841 ttcaatgttg aggtttacct tgagcttttc aggttttacc aacagagaag cgatatggat
     3901 agcttcggga ttgcgtgtac ctaatgtttc gagcagtcgc tgcatcgtca gtcctgtgtc
     3961 tacaatatct tctacgatta caatggtacg tccggcaatg tcttcattca ggccgattac
     4021 ctctttaatc actccggtgg aagtgatgcc ctgataagac gccaacttca caaatgagat
     4081 ttcacaaggg atggtgatgt gcttcagtaa atcagcggta aacatgaacg aaccgttcaa
     4141 cacactaagg aaaagcggat tcttacctgc caaatcgcgg ttaatttcgt tcgctacgcg
     4201 aatcacttct ttctgaattt cttgttcctt aatagaaacg gtaaacaatt tgtcttttat
     4261 ctgaatggta tccataaccg gtaatttaaa aataaccttg caaaaatacg attttttatt
     4321 ctaccccgtg catcatcttc tgtaatttct tcgagagaag gaacagaatc aacgaagcaa
     4381 caccggacat tacgacgaat accataaaga aatcatacat ggtagcaatc tgataaccaa
     4441 agattgactt cacttttccg gcttccggat agagtccgct caacattccc gcaaatttat
     4501 tagctgtggc agtagacaga taccagattc ccatcatcaa ggaggcgaaa cgcagcggac
     4561 tcaatttatt taccattgaa agtccgatag gcgacaaagc tatttcaccc atggtatgaa
     4621 taaagtaaag tcctgtcagc caaatcatgc tcactttcac tccgggaact gcatctttca
     4681 ctccaaaaca gatgaaaaga taacctaaag aaaggagtaa caaaccaatc gcttgtttgg
     4741 taggagaagc gggttccatc tttcgtttgt ttaggaaacc ccatacaccc ggcatgatat
     4801 atgccaggac aactacaaac agtggattga aggattgaaa ccatgaagcc ggcatttccc
     4861 aaccgaaaat gtcacgattc gtctgttcgg acgcaaaaag agttaaagaa gctcccgcct
     4921 gttcgtaggc tgcccagaag aagatgacaa agaaggctac tatatagata acgaaaatac
     4981 ggctgcgttc tattttggtc aatgaaccgt ctaacaaaat cagaacaggg aaaacaatgc
     5041 aggcggtaaa aatgccgata ctcacccaat cgccttcaaa tgcatagtta aagaaggcta
     5101 ttaaagcaat ggtaagaatt gtgattacaa gggtattacg tactttggta cgtttgtcca
     5161 tcttcgggtg tgagatatgg tcggccttgt cttctttctt ttcacgttta gcatcgggga
     5221 taataccaat cggttctccg gaaggagaaa aaagatattt attcttttga gtctcgaaaa
     5281 ggacaacggt gaacagtgtc atgattccgg ctgcaagaaa tccccattta aagtcatgcg
     5341 gatcaccggt atcacccaga taaccacaaa tcaaaggagc agcaaaagag cctacattca
     5401 ctcccatata aaaaatggtg tatgcagcat ccagccgcct gtctccgggt tcgtagagct
     5461 gacctaccag agaagagaca gtgggtttga agcaaccatt gcccaagatc aggaagccta
     5521 gtccgccata catcatccag tgggcaaggt ttgtattatc taaagtggag gcactcataa
     5581 acatcaggaa ttgtccgact gccatcatca ccgctcccca aaacacagaa cgacggattc
     5641 cccaatattt atcggcaatg tatccgccaa tcaacggggt taaataaact agtccggtat
     5701 agctgccgta gatggatgct gccgcttctt tgtcaaacaa taatgcctgc gtcaggaaaa
     5761 gaataaagat cgcacgcata ccgtagtaac tgaaacgttc tgccgtgctt gtcgcgaaaa
     5821 tcagataaag gcctttcgga tgccctttca atgcactcat gaatttatgt gtttagtagt
     5881 ttatggggtg caaaggtaca gaaaaagtag attagatact tctcttatca aacagaataa
     5941 tagggggaat agtaaaaacg agcataaaaa atcctactga tccacttcat tactttttta
     6001 gcagtgtaaa taataaagtg gagatccatc ttaaatgtag gttagctacc accttagcca
     6061 aaagtaaatt cgacattttc gatactggca aaaagcattc cttctctttt cctcaaaaag
     6121 attttgtctt ctcgggccag ccaaccaata gcaagagcta cgtcttcaaa cgtcaaactt
     6181 aattcacggc acaaatcgaa cattgaaagt tcaccttttt catttaagat gcgccatact
     6241 ttcccggcat tcaagccaat ttttgtcttt tccatcatgc aaactttaga agattaaaca
     6301 atccgttatt tagattctaa ttcattgtga gcacaggaaa ttaatgtgat gcacattatc
     6361 tatctccaaa gataacattt ttatcggaaa cggcaaataa tcaaaggctt aatcaggaga
     6421 gggggcgtat caaaagtttg ttcaagaagg tatgaagatg aaggaaaccg taaccacaca
     6481 tgaggtatat agcttaatac tgcctaatgt cggcactata cgacaatttt gaagttgagt
     6541 tattaataga caactgaagt cagctactta gtcaactgca gttgaccatg tagccgacag
     6601 tagtcatcta agtagccaac tacagttggc taatatcatg ccaactattt caatccggtc
     6661 ttcaatcata ttcgttctcc tatgtctttc catattgaag aaacacctaa gcttttgctt
     6721 tgaccgggct tctttcttaa gggtgcgaac agtgtgaaag atgtgaaggg ttaaaaagag
     6781 aaccttaaat cacaacaaac atctgtcaca ctacaactta cgtgtccgtg aaacttgtga
     6841 aaggtacaaa atgattattt ttaataaatc aaaccaccac gagtttgatt catttccctg
     6901 cccccaacaa gtcatctcct tatgattaac aagttttctt cccacaacaa acgggaaaag
     6961 tcagaagaat catgtacatt tgtaatccga aaactaaaag aacatcgcaa tgaaaatatt
     7021 tccaagcagc agtatcaaga aattggacgc ttataccatt gagaacgaac ctattgcatc
     7081 aatcgatctg atggaacgtg cagcaaccgt attaacaaaa gccatcacag acagatggaa
     7141 tacggaaacg ccggtcacta tctttgccgg accggggaat aatggcggag acgctctcgc
     7201 cgtagcccgc atgatggctg agaaaggata taaaatcgag gtatttctct tcaacacgaa
     7261 aggagaactt tcacccgact gccagaccaa taaagaactg gtagaaatga tggaagaagt
     7321 aaaattccac gagatcagta cccaattcgt acctcccgcc ctgacgcccg accatctggt
     7381 aatcgacgga ttattcggtt caggcctgaa caaaccgttg agcggcggat tcgctgccgt
     7441 agtgaaatac atcaattcct cccctgctat ggtagtagcc atcgacattc cttccggact
     7501 gatgggagaa gaaaatacat tcaacgtaaa agctaatatt atccgtgccg acgtaacttt
     7561 cagtctgcaa ctgccgaagc tcgcctttct tttcgcagag aacacggaat ttgtcggaga
     7621 atgggaagtg ctggacatcc aattaagcga agacggtatt gaagagatgg aaacgaacta
     7681 cgaaatgttg gaaatagagc aaatccgttc actcatcaag ccacgcaaac agtttgccca
     7741 caaggggaac ttcggccatg cactattgat tgccggttca aaaggaatgg caggagcctc
     7801 tgttctcgct gcccgcgcct gcctccgttc gggagtaggg ttgctgactg tccatgcgcc
     7861 aatgtgcaac aacgacatct tgcaaacctc catacccgaa gcaatcgtag aaaccgacat
     7921 caacgaaacc tgttttgccg tacctaccga cacggacgac tatcaagcag tcggcatcgg
     7981 tccgggactg ggacgaaacg aggaaacgga agctgccttg ttggaacaac tggaacactg
     8041 ccagactcct gttgtggtgg atgccgacgc acttaatatc cttgccaacc accgccatgc
     8101 ccttacccac ctgccgaagg gttccatcct caccccgcat ccgaaagaac tggaacgtct
     8161 gaccggcaaa tgccaggact cttacgaacg tctgatgaag gcctgcgaac tggcccgtgc
     8221 cgcccatgtt cacattattt taaaaggagc ctactccgcc atcatcaccc ccgaaggtaa
     8281 atgtttcttc aacccaaccg gaaatccggg aatggcaacc ggaggtagcg gtgacgtact
     8341 gaccggagta atcctggcac tacttgccca aggttaccca accgaggaag ccgcaaaaat
     8401 cggcacttac attcacggac tggcgggcga tgtcgctcaa aagaagcaag gaatgatcgg
     8461 aatgatcgca agcgatatta tcacctgtct gccgacagca tggcgacttg taagcgaata
     8521 aaagttaaga acttaccctt ttttcaataa cttcattaac tttgttttca aaaccagtta
     8581 aaaagaaccg aatatgaaaa agttgattat agcagcagga ctacttatga caacgtccgc
     8641 ctatgcacaa accgaagtac tgacaggggt tacccgagga aaagactatg gagtggttta
     8701 cagtcttccc aaaacccaaa tagaacttga aataaaagcc aacaaagtca actatactcc
     8761 gggagaattc agcaaatatg ctgatcgtta cctacgactg accaacgtct ccgccgaccc
     8821 tgaagagtac tgggaactgg ctagcgtaaa agtgaaatcc gtaggtgtgc ccaacagcga
     8881 aactatgtat ttcgtaaaat tgaaggataa gacagtagca ccgctcatgg aactgacaga
     8941 ggatggcatt gtgaaaacga tcaatgttcc ttacagcaat agcagtgtag gcaaaaaagc
     9001 tgctcccgcc cccgcagtcc tccaaaagaa agcgaatcct cgcgaattcc tgaccgaaga
     9061 gattctgatg gctagttcta ccgccaagat ggccgagctg gtggctaaag aaatctataa
     9121 tatccgcgaa agcaaaaatg ccttattgcg cggacaagct gataatatgc cttcagatgg
     9181 ggcacagctt aagattatgc tcgacaatct gaatgcacag gaagaagcca tgacacaaat
     9241 gttctccggc acctgcaaca aagaagagag aacattcact gtccgcctta cccctgacaa
     9301 ggaattcaac aatgaagttg ctttccgctt ctcgaagaag ttaggtgtag ttgccaacaa
     9361 tgatttggca ggaactccgt tttatatcag tctgaaagac ctgaaatcgg tcaagatacc
     9421 acaggaagac ggtaagaaga agaaagattt ggatggaatc gcctacaacg tacccggaca
     9481 agctatggtt acactgaccg acggcaaaaa gaaactttac gaaggtgaac ttcctattac
     9541 tcaatttggt gtgatagaat atctggctcc ggttttgttc aacaagaatt ctaccatcaa
     9601 agtttatttt gatccgaata cgggaggatt gctcaaagtg gacagagaag aagggaaata
     9661 gaaaaacgag gaagtgaact tctaaaaaac aaagaatatg gttggtgaag gacatgcatt
     9721 cgacatgata cgccgaataa aagagggacg ggaagcttcc cgcctacgtc gtgaacgtgc
     9781 taacgataag ttgaagcatc taaaccgtgc aaacgaacct tatccactac ccaacaccac
     9841 ccccgaagaa atggaacgta tcatccacga ctcggagaaa aagaaagaga aagacagcaa
     9901 ttattttgtt tggggaacgc ttattatcat gggggtcctg atagcaattg ccgtcatact
     9961 ttgggctgta tttatcaaat aaataataat aagttcctat ttatacgact ggtatcacca
    10021 gttttataaa tccatctttc tgcatttgag aaagataagc cgatacacgc gactcgtagc
    10081 cctcttcatt ttgaaagtgg tctgcgagtt tttctataat ctcacgaaca ttgcgttttc
    10141 catctatcag ttcccataca gccgtaccgt gttcttccaa tttcacatga agttctttcg
    10201 acattccttt cggcacaagg aagcgttgca tccacggata tttaaaacgg ggaaaggaga
    10261 gcacaattgt ctccccttcc ctttctgctg taatatgttc actgcgacag ggaatgacct
    10321 ctaacaggtt gattttctct ttggcagcca tacttcttat tttttatttc agagtattca
    10381 tactgatact cttctgttta caccttgata caaaattcct ttgtcacttt aggtattgaa
    10441 tttcctagtt acttttggat attcgcctct tccagaccgt atcccttctt cttgttctct
    10501 gcctttaaca tcaaagccac aatcagagca agcacaccaa agagagcaaa aatagccatc
    10561 ggcaacgtgt agtcataagt ctgtgcaccg tctactaccg gacctttgca ataagtattc
    10621 aacacccatc cgatcaacaa aggaacaccc atcaatcccc agttctgtac ccagaaaatc
    10681 aatgcgtatg ctgtacccaa ctgtttttcc ggaataatct tcggaacaga cggccacata
    10741 gctgaaggca ccaacgagaa ggcaaatccc aatataatca tgatgatagt agcaaaccac
    10801 catatattca gtataggcag agcgaacatc gtatgcacaa aaataagcat cactgatccg
    10861 attatcatca atgtggctcc cttaccgata cggtcataaa gcgagccgaa caacggagtc
    10921 agaataatcg caccaatcgg caacaatccg ggaatcgttc ccgccaactt cggatctacg
    10981 ttatatttct gcaccatcaa gtcggcagca tacttgataa aggggaatac agccgagtag
    11041 aacaatacac atagtaatgc aatcagccag aatcctttat tggtaatgat atacacaata
    11101 tctttcatac ggaacggctc ttccggttcc aatccctctg catccaaaga agcatccaac
    11161 ttcttatcat agaaagtata aaggaagaaa gcaatcgtac ccacgcacaa cataatcaga
    11221 caaaacaaaa tcggagcagg aatattggta tggaatgtgc cactctcatc cgtagatccg
    11281 aaaaagtcgg ccaaaggaac cgtaagcacc attgccagag ttgttccgat acgtgccgta
    11341 gccatttcaa gtcccatagc caacgccatt tccttaccct tgaaccattt cacgataatt
    11401 ttggaaactg tgatactggc aatttccaca cctacaccga agatagcata ccccaatgcg
    11461 gccagggtta cctgtgtttt gaatccaaag agcatggcac cttccggaaa agtagtagaa
    11521 atcgcatagt atttcaatcc acaaccaaac accatcaata agcaagctcc cattccggtg
    11581 aaacgaactc ccatcttatc caaaatgata ccaccgaaaa tcagcatcaa taggaataca
    11641 ttaaaccacc cgtaagcgct tgtgaagaaa ccataatcaa gactgtccca tagtagttct
    11701 ttctcaagca tgggttttaa aggagacatt acgtcggtga ggaaatagcc gcatagcata
    11761 gtaaatgcga ctaatgctag aacactccat cggagtacgg cggagtcatt caatttctgt
    11821 ttcaaatgtt ctgtcattgt tatatttaaa aatagtagtt aataatcttc atacgaccaa
    11881 caaaggtagt taaatctcgt ttgtttctat caaaaagaga ttgtttttac aagaaaaagt
    11941 taagtgcgga ttacactgac cacgcggaag attgaaaatc cgtgtaatct gcgtaatccg
    12001 cacttaaata tcaaagaaat gcagcatccg tctgcacctt cccattaatg gttttacccc
    12061 aaagtcttac ctgacaacgg agtgaattac tctgctgcag gagcaggagt ttcagtagcc
    12121 ggtgccggag tttctgtagc aggtgcattg gtagcaggag cttcagtttg cggcgcagcc
    12181 gtacctgcgg gtaagttata cgggttagtc tgttgttctt tctgtgcctg ttccaacact
    12241 gcgtctttag caacagcaga gcgaggaact acataagcag tagcaatgct cattaccacc
    12301 atgaagatag ctaagcccca tgttgctttt tccagaaaat ctgtagtctt gcgcacgccc
    12361 atgatggcgt tagatgaaga gaaaccagaa gcaagtccgc ctccttttga gttctgaatc
    12421 agcacgatga aacacatcaa caaggctgca ataaccatta agataacgaa taataagtac
    12481 atttttagtt attttgaatt agcgttaata atcaatttct ccaaaaatct gatttggtct
    12541 gcaaagtaag catttttttt tggatatttc aagcttaatt ttttaattat ttcaagagct
    12601 tttgaatatc gttgctgttt aacatagatt tttgccaaag tttccgtaaa acagctgtca
    12661 tcttcctctt cttccttcat cgtttcttct tcggtaagtt cgtccgaaga ggttggcgaa
    12721 gatggcattt cttctcttaa aggtttcttg cagaggggag agtcgctctc gctcttttct
    12781 ataaagtcgt caatcagttc gtagcctttg agtttgggcg tttcttcggc cggctgttcc
    12841 gtggccggag tctcctccaa aagataagag gtgtaatcca tcgaatagtc gaagctggtg
    12901 cgggcagtca cctcttcggg tactgtggac aagaaagcgt cgatcaatgc taatgtgcgg
    12961 tctacggacg gttcgtcttt cagcacctcc gtgagaggta ctcccttttt ccgtgcctgc
    13021 acatcatagc ggtcaccttc aatcaaccgg aacaactgcc gtctgtctgc aatgtaaaga
    13081 actgctttcc gcagttctcc accgaaacta atatcatgga gaatatacag attcttcaga
    13141 tacagcagac gaagtgactg aaaatacgga tacctcgcaa gaagattgcg cagttcgtac
    13201 aaagtatccc tattcagcgt ctcgggatgc tgaatccatt gttgaaagtt aacagaagtc
    13261 atttatatta ccagtttgct acagttgcat taaaaatttg gtcggtgatc tctttagaca
    13321 tttcagcaat caatccgtcc tgtacggcag tcagcaactg gctagagtcg taggtacgga
    13381 acgcagaaaa ctgttgttca aagtcttcgg catgattggt gttgttgaca aaacgtacat
    13441 tgacggtaat agtcaacttc gtctccgaag aataaccgtc ggcagatact gcctggttgt
    13501 actgattgta tcctgtgatt tctccgtcaa tctgcaagtc ggcattctga ttcggcttga
    13561 gcagttgcag acgggtctgc cggatgaaga tatctttcaa gtcctcattg aatttggttg
    13621 ctaacggagc atatacatac tccgacttga tcgggaagtc ggctatcgaa atggtcttta
    13681 ccttatcata attgatagac gatccgttaa acttatagga aacagtgcac gcaatgacta
    13741 ccaacggcaa gccgaacagt aacaaagggc gtattatttt cttaatccaa ttcatattct
    13801 tttatttttc tataaagtgt acgctcggaa atattcaagt ccttggccgc actcttccgc
    13861 tttccatgat gcctctcaag tgccttgcgt atcatttctt tctccacttc gtccagtgac
    13921 aaaggagatt cttctacata ttcttccgtg tcttgtatgt catcatcatc cttgcaaacc
    13981 gtgggctgca tggtatgaat aatagcaggt accgaaggtt gatgcgccgt cactaccgga
    14041 gtagtaacca ccgttcccat ttgtcctacc tgccccacct gtccggcacg ttccgccatc
    14101 aggttgtgca ccatcttctt cagctccgcc acttcctggc gcatatcgaa cagaacagaa
    14161 taaagaatct cccgttcgct ctcaaagcct ttactctcac gcgttcccat caacgcggga
    14221 agacgttgcg tattttgtgc gggaagataa ttctgcaaga tagcagcaga gatctcccta
    14281 ttggtttcaa tgatagatat ttgctcggtg atgttcttca actgacgcac gtttccgggc
    14341 cacgggtaag ccaacaactc tttcttcgca tcctccgtca actgaatagc aggcatccga
    14401 tatttctctg caaagtctgc ggaaaactta cggaacaaca aaagtacatc atcaccacgt
    14461 tcacgcaaag gcggtatttg gataggcacc gtattcaacc ggtaatataa atcttcacgg
    14521 aaacgtcctt ctgcaatcgc ttgtgtaaga ttgacgttgg tagctgccac cacacgcaca
    14581 tccgtttttt gtactttgga cgaacctact ttcataaact cgccactctc cagtacacgg
    14641 agcaaacgtg cctgggtaga catcggcaac tcccctactt catcaagaaa aatagtacca
    14701 ccgtcagctt cgccaaagta ccctttccgt tcgccaatcg caccggtaaa cgcacctttc
    14761 tcatgtccga acagttcgga atcaatcgta ccctccggaa tagcgccaca gttgacagca
    14821 atatactgcc cgtgcttcct ccggctatat tgatgaataa tctgcggaaa actttctttt
    14881 ccgactccac tttctccggt aatcagcaca gacaaatcgg taggagctac ctgaatggca
    14941 acatctatgg cgcgcgacaa tgcttcagta tttccaataa taccaaaacg ctgtttcact
    15001 tgttgtatct ctgctttcgt catcactcgt ttttaatctt cgtctactgt atccagcttc
    15061 agtttatcac tatcgtcacg tttctcgtaa tactgtttac gcaacggatt ggcacgagcc
    15121 actttttccc gctgacgatt acggaacacg tcgatggcaa catagattgc ctgacggaaa
    15181 gaatcttcac aagccactcc cttgcctgca atatcgtatg catgaaatat ttcatgagtg
    15241 catgtattat tatgattaaa aaatatacgc ttatcaaatt agagaatgaa tatttggaac
    15301 tacaaatatt gccggaagat
//
