LOCUS       c00016_gnlPro..        23026 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BMGDPBIK_16.
ACCESSION   c00016_gnlPro..
VERSION     c00016_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 23:59:15
            Original ID  :: gnl|Prokka|BMGDPBIK_16
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 23026
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23026
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[7773:13026]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      7774..13026
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..23026
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23026
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             complement(3..674)
                     /locus_tag="ctg16_1"
                     /transl_table=11
                     /translation="MLETDNYEKFKKDILQLAGIDLNSYKEKQMRRRINTLITKNNVKT
                     YNDYVALIKKDKEKFDQFINFLTINVSEFYRNPDQWKILEGQVFPELIKKFGKNLKIWS
                     AACSTGDEPYSLVMALSRQVPLANIKIIATDIDNQVLDTARMGLYNEKSIASVPDDLKK
                     KYFTKVGSSYQISDEIKKRVEFKKHDLLKDPYPSGCNLIVCRNVVIYFTEEAKDVIYQK
                     FH"
     CDS             complement(805..1929)
                     /locus_tag="ctg16_2"
                     /transl_table=11
                     /translation="MSEMSFEQMLEESFKTIRNGEVVEGTVIDVKPDEIVLNIGYKSDG
                     IITRNEYTNEANVDLTTLVSVGDTMEAKVLKVNDGEGQVLLTYKRLAAEKGSKRLEEAF
                     ENKEVLTAKVAQVLDGGLCVIVDETRVFIPASLVSDSYEKDLSKYKDQDIEFVISEFNP
                     KRRRIIGDRKQLLVAKKLEQQKELFAKIKVGDVMEGTVKNVTDFGAFIDLGGADGLLHI
                     SEMSWGRVESPKKVFNVGDHVRVFIKDINDTKIALSMKFPAENPWNGAAEKYAVGNVVK
                     GKVARMTDFGAFVELAPGVDALLHVSQIAKEHIEKPSDVLKVGQEIEAKIVDFNEDEKK
                     ISLSIKALLAPETNESEDADVADVDIDAVAAEEN"
     CDS             complement(1910..2779)
                     /locus_tag="ctg16_3"
                     /transl_table=11
                     /translation="MKITLAKSAGFCFGVKRAVDTVYEQLEMSAAERQPIYTFGPIIHN
                     EEVVRDLEEKGVTVLESVEELEERAAHGGTVIIRAHGVEKGISEKIKELGYTLVDATCP
                     FVLKIHRLVEKHSAEGAQIVIIGNEKHPEVKGIKSWSLDPHTAVIATPEEAEKYQAESG
                     KKVCIVAQTTFNYNKFQELVEIINKKGYDIIVLNTICNATEERQTEAAKIARDVDAMIV
                     IGGRNSSNTQKLFEICKNECNNTYYIQTVKDLDITCFESIDSVGITAGASTPNKIIEEV
                     QKNVRNEL"
     CDS             complement(2793..3458)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Cytidylate_kin"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_4"
                     /sec_met_domain="Cytidylate_kin (E-value: 1.5e-79,
                     bitscore: 257.8, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSMNIASDGPAGAGKSTIAKRLAKKLGFIYVDTGAMYRAMAYYFL
                     QHNIDAKDENAIAAACPDVDVTITYENGEQQVLLNGENVNGVIRNEEVGNMASSTSVYP
                     VVRKKLVELQRQLAKSADVIMDGRDIGTCVLPDAQVKIYLTASSATRAKRRYDELTEKG
                     VSCDLAEIEKDIIDRDYRDMHRETSPLRQAEDAVLVDSSEMNIDEVVDAIYQVYSEAR"
     CDS             complement(3549..4814)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HI0933_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 58.2; E-value:
                     2.5e-18)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_5"
                     /sec_met_domain="HI0933_like (E-value: 1.2e-135, bitscore:
                     443.4, seeds: 46, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKIIVIGGGPAGMFAAIAAAETGSQVILLEKNEKLGKKLFITGK
                     GRCNITNAGDMDNLFANVMTNAKFLYSAFYSYDNQRVIDFFERNGLRTKTERGNRVFPV
                     SDHSSDVIATLQKVLKEKKVKVMLHTQVQSLLMESSGEDAPENIVTGVKLTDGTTMPAD
                     AVIIATGGFSYQTTGSTGDGYRFAKEAGHTVTDIRPSLVPFLAKEDYVRQMQGLSLKNV
                     EVRILNEKKLLYQEFGEMLFTHFGVSGPLLLSASAAIKPSLTAGELSMFIDLKPALTEE
                     QLDHRLLREFDEAKNKQFKNSIGGLFPAKMIPVMLDLSGIDLEKKVNEITKEERRHFIG
                     LIKAFPVTLCGLRDFNEAIITKGGVKVKEVNPSTMESKLVPHLYFCGEVLDLDAMTGGY
                     NLQIAWSTGYLAGISAAQPDER"
     CDS             complement(4807..5739)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SIS"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_6"
                     /sec_met_domain="SIS (E-value: 3e-24, bitscore: 76.5,
                     seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGSKNDLSNRINESYSKLSKGQKLLATYITDNYDKAVFLTAAKLG
                     EVVGVSESTVVRFAMHLGYRGYPEFQSALEELVRNKLNSIQRMEVTYGRISQSKILESV
                     LKSDAEKINSTLEKIDQAAFEMAVDTILNAKHIYIIGIRSCAPLASFMAFYFTLMFENV
                     RLIQTSSSSEIFEQMVRIGKEDVIIGISFPRYSMRTLKAMEFANNRSAKVITLTDSVHS
                     PMNLYSSCNLIADSDMASIVDSLVAPLSVINALIVALCMKKQRDVAKTLEMLEGIWDEY
                     QVYENDEINAIDDSIKMRYAKIGDSDFHE"
     CDS             complement(5835..7640)
                     /gene_functions="resistance (resist) ABC_efflux (Score:
                     272.8; E-value: 3.5e-83)"
                     /gene_kind="resistance"
                     /locus_tag="ctg16_7"
                     /transl_table=11
                     /translation="MENFERKTSPKNGIDTENWFIESYRRYKGHPIRILIALYKGNYHK
                     FVMAVICFFIKHACVWVLPIITANIINDVTQKNPDTVRNIWISAALEIGLIALNIPMNY
                     LYTSYKSLATRYAETGLRKALIRKLQQLSIAYHVETQSGRLQSKIMRDVEAVETLSTQM
                     FLSILNIALNIGVALVVTASKSKIVFVFFLLTTPVAAITMVSFRSVMKKRNTEFRKEME
                     ETSARVMEMVELVPVTRAHALEDEEVHKMSGQLFTVAEKGYKLDLVQALFGSVGWAVFQ
                     VFQVVCLAFTGYLALRGRIMAGDITLYQSYFATVVNQVSAIVTLLPTIAKGIESVNSIG
                     EVLLSEDVEQNEGKKQLEDVTGIFDFEDVSFHYKNSDKPVLNHLNLHVKQGETIALVGE
                     SGAGKSTVLNLVIGFHLADGGKVLLDGNDMRKIDLRTYRKHLAVVPQTSILFSGTIREN
                     ITYGNEHVSDEELERVIKAANLTDLMESLPNGVDTMVGEHGGKLSGGQRQRIAIARALI
                     RDPEVIVLDEATSALDSISEKLIQEALENLTKGRTTFIVAHRLSTIRDADKIAVLADGH
                     CVEYGTFEELMARKGEFYRMKMIQS"
     CDS             complement(7774..9192)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: HMGL-like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: PYC_OADA"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_8"
                     /sec_met_domain="HMGL-like (E-value: 3.6e-45, bitscore:
                     145.7, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="PYC_OADA (E-value: 1.2e-58, bitscore:
                     189.3, seeds: 434, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEVVKKPLKITETVLRDAHQSLIATRMTTEQMLPIVDKMDKVGY
                     YAVECWGGATFDASLRFLKEDPWDRLRKLRDGFKNTKLQMLFRGQNILGYRPYADDVVE
                     YFVQKSIANGIDIIRIFDCLNDLRNLQTAVSACNKEKGHAQVALSYTLGDAYTLDYWTD
                     MAKRVEDMGADSVCIKDMAGLLVPQKADELVRAIKEVIDIPLELHTHYTSGVASMTYMK
                     AVEAGCDIIDTAMSPFALGTSQPATEVMVEAFKGTEFDTGLDQNKLAEIADYFRPMREE
                     ALESGLMNPKVLGVNIKTLLYQVPGGMLSNLISQLKEQGKEDKYEEVLAEVPRVRKDLG
                     EPPLVTPSSQIVGTQAVFNVLMGERYKVATKETKDVLLGKYGQTVKPFNPEVVDKVLGD
                     EKKNAITCRPADLLEPELDKIEAEMKQWKQQDEDVLSYALFPQVATEFFKYREAQQKKV
                     DATIADTKNGAYPV"
     CDS             complement(9238..10386)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_9"
                     /sec_met_domain="OAD_beta (E-value: 4.1e-158, bitscore:
                     517.0, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYFTETMGNLLHQTAFFNLTWGNFVMILVACIFLYLAIAKGFEP
                     LLLVPIAFGMLLVNIYPDIFAAPEQMSNGVGGLFHYFYTLDEWSILPSLIFLGVGAMTD
                     FGPLIANPISFLLGAAAQFGIFGAYFLAILMGFNDKAAAAVSIIGGADGPTSIFLAGKL
                     GQSGLMGPIAVAAYSYMALVPIIQPPIMKLFTTKKERAIKMQNLRPVSKLEKILFPIVV
                     TVVVCLILPTTAPLVGMLMLGNLFRECGVVRQLSETASNALMYIVVILLGTSVGASTSA
                     EAFLNATTLKIVALGLIAFMFGTAAGVLFGKLLCFITKGKINPLIGSAGVSAVPMAARV
                     SQKVGAEEDPTNFLLMHAMGPNVAGVIGTAVAAGVFMAIFGI"
     CDS             complement(10403..10774)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 57.7; E-value:
                     2.6e-18)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_10"
                     /sec_met_domain="Biotin_lipoyl (E-value: 1.4e-18, bitscore:
                     57.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSYTITVNGNVYDVTVEENGAVSAPAAAPRRAAAPAPAAAPKAA
                     APAGGAGNVKIEAGAAGKVFKIESSVGASVKKGDTILVLEIMKMETPVVATEDGTVASI
                     NVSVGDMVEAGALLATLNN"
     CDS             complement(10840..11580)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_11"
                     /sec_met_domain="OAD_gamma (E-value: 1.6e-27, bitscore:
                     87.2, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKKLSLMLCLCFMVLAMTACGTDPKSVDYFGMSYSDIQDNMEQT
                     VSALVSFSDEDIQSGAEYYDSNGMDAFAHLLTSWGETVSDLGSYQGLGDLTVTKAQKTV
                     TADQVLHFSDRDVVVSYVYEYNYETEAPELTDASADLVYSLGEKMGKAGMNTLMGMGTV
                     FVVLILISLIISCFKVIPYLQNKKANAGAKKDVADPVVEQIEQREETSQLTDDLELVAV
                     ISAAIAAAEGTSADGFVVRSIHRR"
     CDS             complement(11593..13026)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Vparvula"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_12"
                     /sec_met_domain="CT_Vparvula (E-value: 4.1e-125, bitscore:
                     409.3, seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSSNDSLAMQRITKLVDENSFMEIGSLVTARNTDFNLADTDTPS
                     DGVITGHGLVDGNLVFVYSQNAAVLNGTIGEMHAKKIAAVYDMAMKMGAPVIGFIDCAG
                     MRLQESVDALNGFGEIYAKEVAASGVVPQISAIFGSCGGGLAVVPALSDFAFMESKGKM
                     FINSPNAIEGNRIEKCDTSSAEFQSEKNGCIDAVGTEDEIIAEIRELVSVLPLNNEGDV
                     YTSECQDDLNRACENMAAMKGDPRYLLSEISDGHVFFETKKNYAKDMVTGFIQLNGMTV
                     GAVANCSEVYDEEGKKAEEFSGALTARGCNKAAEFVNFCDAFEIPVLSLTNVKGYAATV
                     CAEKGLAKALARMTMAFADATCPKVNLITGNAIGSAYVTMNSKAIGADFTYAWEDAKIG
                     MMDGELAAKIMYADASADELAAKAKEYDALQSSVMTAARRGYVDLILDPADTRKYLVDA
                     FELLYTKCAGVPDKKHGTK"
     CDS             complement(13204..14448)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S11"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_13"
                     /sec_met_domain="Peptidase_S11 (E-value: 2e-50, bitscore:
                     162.6, seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWKKLLAWILVTVILTGYGIQIVEAFDQKENVRMEKVIEKPDQNS
                     LYAKAAVLMDADSGRILYEKNGHQAMANASTTKILTCIIALENCDLDSEVTVSTLAASQ
                     PKVHLGMREGQKFYLKDLLYGLMLESYNDCAVAIAEHIAGTTGDFAKLMNDKAEEIGCE
                     DSYFITPNGLDAKNENGFHHTTAADLSLIMRYCIKTSEMAEQFLTITREGQYQFSDIDG
                     KNSYTCCNHNAFLQMMDGALSGKTGFTGNAGYCYVGALKRDDRTFIVALLACGWPNNKT
                     YKWADTKKLMQYGISRFRKISLDEIELDAGEYAPVQVVDGQGTKIGEEVTTELEVAPVK
                     ENVELLIEKDQEVHIEYQLSRKLYAPVTEGDFIGEITYLLGDEVLAKRVVTVKNTVKRI
                     DFCWCVKKTAELFPM"
     CDS             complement(14543..15112)
                     /locus_tag="ctg16_14"
                     /transl_table=11
                     /translation="MEEKKYEAIVEAILFTMGESVELERIAKTLELDTERTKKIIEHLM
                     QRYEDDGVGVKIMELDGSYQMCTKGEMYEYLVKIAKQPKKHVLTDVLLETLSIIAYKQP
                     ITKAEIEKIRGVSCDHAVNKLVEYNLVCELGRLDAPGRPLLFGTTEEFLRSFGVQSIDE
                     LPVLSPVQVEEFKQEAEAEMHMKLDI"
     CDS             complement(15179..15928)
                     /locus_tag="ctg16_15"
                     /transl_table=11
                     /translation="MELTVKLQVFEGPLDLLLHLLEKNKVNIYDIPIVEITNQYMEYIA
                     EMRRQDLNVMSEFLVMAATLLDIKSKMLLPAKESEDEEEEDPRAELVQQLLEYKMYKCM
                     AYELRDRQIDAEKVWFKAPTIPPEVLAYEEPVDVNELMSGVTLARLNDIFQSIIKKQAD
                     KIDPVRSKFGRIEKEEVSLSDKMTYVEEYSLHHGHFSFRSLLEAQSGKMEVVVTFLAIL
                     ELMKMGKIVVSQEYTFDDIKIESKIAA"
     CDS             complement(16021..16155)
                     /locus_tag="ctg16_16"
                     /transl_table=11
                     /translation="MVTFGMKQEDAGSTVPCTRRLRPSRMETMNFKNMPSVGFCYNLF"
     CDS             16865..17278
                     /locus_tag="ctg16_17"
                     /transl_table=11
                     /translation="MELIAVIMGAPDIKSRSADATTLLNYGFGKCRIYCDSHEDKLDDL
                     PVEKGLADSVGIIYQRPFQYMTTDGSDLTGITKSIELPENVTAPVKKGNTAGKAVYSLN
                     GTPIGSVNIVYADTVDAADYKDYFCRTLLYFVP"
     CDS             complement(17373..18614)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PLDc_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_18"
                     /sec_met_domain="PLDc_2 (E-value: 3.3e-24, bitscore: 76.4,
                     seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDAVNRQVEALFQRDSAVEKGLEKESRSAYLQSSYIDKWAGFPLY
                     QNTQTKYYSCGEEMFPDMLEALRGAKHFIFLEYFIIEEGYMFNTILDILEEKAKAGVDV
                     RFIYDDVGSINSISFGYYKKLQERGIPCVTFNPFKPLISVVMNNRDHRKIFVVDGYIGF
                     TGGINLADEYINKVKRFGYWKDTGVRIEGEAVWSLTAMFLEMWNYINRSTEDYSRFLPS
                     VYREKEFTSDGFVQPYGDSPLDNENVGENIYLNIINRAKNYVYIFTPYLIIDHEMLICL
                     SNAAKSGVDVRIVTPGVPDKKAVYLLTQSYYEPLLKNGVKIFQYTPGFIHAKCFVCDDE
                     IATVGSVNLDYRSLFLHFECGVFMYRSKAVMQVKEDCLRTFEESEEMDVSFCRRRRLPV
                     RMVQSLMRLFAPLL"
     CDS             complement(19023..20066)
                     /locus_tag="ctg16_19"
                     /transl_table=11
                     /translation="MPSVKHSSEYSEKFNIFLSFLAENKFLHIIIWKFFDRMGETMDRV
                     KKMIHTDYAYRSGLSGQNVTVAVMDTGIVAHPDFEDRIIYFHDFCYGRKEMYDDNGHGT
                     HVSGIIAGNGKMSEQYLKDTAHKVRIYSGVAPKCRIIMLKVLDENGNGNTKKVLDAVMW
                     VKENRERYHIKILNISVGMLPGAGVEEQRKLLYAIDELWDAGIMVVAAAGNNGPKENTV
                     TIPGISRKVLTVGSSDDDTYDRGRKVLKTGYSGRGPTACCIVKPEILAPGTGITSCSKD
                     KSGYQVKSGTSMAAPVVSGALALAFEKYPSFTPAEMKLRLYERAYPRSAQLGRIGWGMI
                     HVDHLVR"
     CDS             20152..21675
                     /locus_tag="ctg16_20"
                     /transl_table=11
                     /translation="LNKKLKEKFDESVNAVLPITVIVLLLSIFVVPMETGTIALFLVGA
                     FMLIIGMAFFQLGAETAMTPLGEGVGSSIMKTRKLPVLIGVCFLMGIIITLAEPDLQVL
                     ANQVPSIPNNTLIFTVALGVGVFLVIAVLRILFRISLPVLLCIFYIALFFLSFAAPADF
                     IAVAFDSGGVTTGPMTVPFIMAIGVGLSATRNDKNGSSDSFGLISFCSVGPVLMVLLLG
                     IFYHPTGAAYNETTIPDVITMQDVIREFVHMIPDYAKEVLLSILPVIFVFLIFQLISRR
                     YHKPQVIKMIIGLLYTIIGLILFLTGVNVGFAPVGSLLGSSLAGQPWKWILIPIGALIG
                     YYIVKAEPAVQVLNRQVEDVTNGSISRDTMNLSLSIGVSASVALALLRVLTGLNIYWLL
                     IPGYLIALILTRFVPKVFVGIAFDSGGVASGPMTSTFLLPLAMGACTAIGGNVVTDAFG
                     VVAMVAMAPLIAVQVMGVSYNMKLKKASTPAAAIIGIDDNEILDFEEDF"
     CDS             21678..22373
                     /locus_tag="ctg16_21"
                     /transl_table=11
                     /translation="MQEQKKREAYRCLVIITDSHIREQLCEFLADSHIPVYYQMHGIGT
                     ASSEWLELCGLGSIQKSITLCFIPNGRKKILLAEMNQALSLHKKGTGIAVSIPMNGMQG
                     FLYKLLNEHTAESDGEEVEKEVKKMSEPITHAMILVTINQGYSDAVMNTARAAGATGGT
                     ILKGLRCSPGKSAVIFGITIQEEQEIVAIVVPKDKKTEIMQAISSAHGMDSPAHGVAFS
                     LPVDGIMGL"
ORIGIN
        1 ttatggaact tctgatagat cacatctttt gcttcttccg tgaaataaat aaccacatta
       61 cggcagacga tcagattgca gccactcgga tatggatctt ttaacaggtc atgcttttta
      121 aattccaccc tttttttgat ctcatctgaa atctgatagg aagaaccaac ttttgtaaaa
      181 tacttctttt tcagatcatc cggcacagag gcaatactct tttcattgta cagtcccatt
      241 ctcgccgtat caagcacctg attgtcgata tccgttgcaa tgatcttaat atttgcaagc
      301 ggaacctgtc ttgaaagtgc catgacaagg gaatacggtt catctcctgt tgaacatgcc
      361 gcactccaga ttttcaggtt cttgccaaac tttttgatca gttccgggaa tacctgtccc
      421 tctaatatct tccactgatc cggattacga tagaattcag aaacattgat tgtcaggaaa
      481 ttgatgaact gatcaaattt ttctttatct ttcttaatca gtgctacata gtcattgtac
      541 gtcttaacgt tgttcttcgt gatcagcgta ttgatccggc ggcgcatctg tttttccttg
      601 taagaattca gatcaattcc ggcaagctgc aaaatgtcct ttttaaattt ttcataatta
      661 tcggtttcca gcataatcta ctttcctcct gtttcctttt gcacaaaagt tctgtaaaac
      721 cagatttact ttcatgccat atcaaaaata ggctttgcac attccgtgaa agcctatttt
      781 tatccatatt actgtatacg gaatttagtt ctcttctgct gcaactgcat cgatatcgac
      841 atctgcaaca tcagcatctt ctgactcatt tgtctccgga gcaagtaatg ctttgatgga
      901 aagactgatc ttcttctcgt cctcgttgaa atcaacgatc ttagcttcga tctcctgacc
      961 tacttttaat acatcagatg gtttctcaat atgctctttt gcaatctggg aaacatgcag
     1021 taatgcgtca acacccggag caagctctac gaatgcaccg aaatctgtca ttcttgccac
     1081 ttttcctttt acaacgtttc caaccgcata tttctctgca gcaccattcc atggattctc
     1141 tgccgggaat ttcatgctga gtgcaatttt tgtatcgttg atatctttga tgaatacacg
     1201 cacatgatca ccaacattaa atactttttt cggactctct actctgcccc atgacatctc
     1261 agagatgtga agcagtccgt cagctccgcc aaggtcaatg aatgcaccga agtctgttac
     1321 atttttaaca gttccttcca taacatcacc aactttgatc tttgcaaaca actctttctg
     1381 ctgctctaat ttcttagcaa ctaaaagctg ttttctgtcg ccgatgattc ttctgcgttt
     1441 tggattgaac tcgctgatca cgaactcgat atcctgatct ttgtacttgg ataaatcttt
     1501 ctcatagcta tcagatacaa ggcttgccgg gataaatact cttgtttcat ccacgatcac
     1561 gcagagaccg ccgtctaata cctgtgctac ttttgctgtt aatacttctt tgttttcaaa
     1621 tgcctcttct aatctcttgc tgcctttttc tgctgcgaga cgtttgtatg tgagtaatac
     1681 ctgtccctca ccgtcattta ccttaagaac ctttgcttcc atggtgtcgc cgacagatac
     1741 cagtgttgtt aaatcaacgt tagcttcgtt cgtatattca ttacgagtaa tgattccgtc
     1801 tgatttgtag ccgatattca atacgatctc atcaggtttt acatcgataa cggtaccttc
     1861 aactacctct ccatttctta ttgttttaaa tgattcctcc agcatttgtt caaagctcat
     1921 ttctgacatt cttttgaacc tcctcaataa ttttgtttgg ggtagaagcc cctgcggtaa
     1981 tacctacgct atcgatggac tcaaaacatg tgatatccaa atcttttaca gtttgtatat
     2041 agtaagtatt gttgcattcg tttttacata tttcaaacaa cttctgcgta ttggaactat
     2101 ttctgccccc tatgacaatc atggcgtcca catcacgggc aatctttgct gcctcagtct
     2161 gtctttcctc ggtggcattg cagattgtat ttaaaacaat tatatcataa ccttttttat
     2221 ttataatttc aactaattct tgaaatttat tgtaattaaa tgtcgtttgt gctacaatac
     2281 ataccttttt cccagattct gcctgatatt tttctgcctc ttccggggtt gcgatcacag
     2341 ccgtatgcgg atcaagcgac cagcttttga ttccttttac ttccggatgc ttttcattcc
     2401 cgataattac gatctgcgcc ccttcggcac tgtgtttttc cacaaggcgg tgtatcttta
     2461 acacaaacgg gcaggttgcg tccaccaatg tatagccaag ttcttttatt ttttcagata
     2521 tgcccttttc cactccgtgt gcacggatga tgaccgttcc gccatgcgcc gccctctctt
     2581 cgagttcttc tacgctctct aaaacagtca ctcctttttc ttccagatca cgcaccacct
     2641 cttcattgtg gatgatcgga ccgaatgtat agattggctg tctctctgcg gcactcattt
     2701 ccagctgctc atacacggta tcgaccgcgc gctttacgcc aaagcagaaa cctgcacttt
     2761 ttgccaatgt tatcttcata ttttatgttt ccttatcttg cctctgaata aacctgataa
     2821 atggcatcta ccacttcatc aatattcatt tccgaactgt caaccaaaac agcatcctct
     2881 gcctgacgaa gcggtgatgt ttcacgatgc atgtcacggt aatcacggtc aataatatct
     2941 ttttcgatct ctgcaagatc acagcttact cctttttccg tcagctcatc gtatcttctc
     3001 tttgcccgtg tcgcagaact tgctgtcaga tagattttga cctgtgcgtc cggaagaaca
     3061 cacgttccaa tatctcttcc atccatgatg acatctgcag actttgcaag ctgacgctgg
     3121 agttccacta gctttttgcg gaccaccgga tagacgcttg tggaagatgc catatttcca
     3181 acttcctcat tgcggatcac accatttaca ttctctccat ttaaaagtac ctgctgttct
     3241 ccgttttcat aagtgatcgt gacatccacg tccgggcatg ctgccgcgat cgcattttca
     3301 tcttttgcat caatgttatg ctgtaaaaaa taatatgcca tcgcgcggta cattgctccc
     3361 gtgtccacat agataaatcc aagttttttc gccagccgct ttgcgatcgt gctctttcct
     3421 gctcctgccg gtccgtcact tgcaatattc atactcatgt tttattctcc ttttacattt
     3481 tgctgtgttt tttatttcct attcttttgt ccataacaat ccatagattt ataaagcttt
     3541 atcctctgtt atctttcatc cggctgcgcc gctgagattc ccgcaagata accagtggac
     3601 catgcaatct gtaaattata accaccagtc atcgcatcca ggtctaacac ctctccgcaa
     3661 aaatataaat gcggcaccag ttttgattcc atcgtagacg gattgacttc ttttactttc
     3721 acgccgccct tcgtgatgat cgcttcgtta aaatcacgga gtccacacag tgtgaccggg
     3781 aatgccttga tcagtccgat aaaatgtctg cgttcctctt tggtgatctc attgaccttt
     3841 ttctccagat cgattccgct aagatccagc atgaccggaa tcattttagc cgggaaaagc
     3901 ccaccaatgg agtttttgaa ctgcttgttc ttcgcctcat caaactctct taacagacgg
     3961 tgatctaact gttcttccgt aagtgccggc tttaaatcta taaacataga aagttctccg
     4021 gccgtaagag acggtttgat agctgcactc gccgataaaa gcagcggccc gctgacacca
     4081 aagtgtgtaa acagcatctc gccaaactcc tgatacagca gttttttttc atttaaaatg
     4141 cgtacttcca cattttttaa tgaaagtccc tgcatctgcc ggacatagtc ttcttttgcg
     4201 agaaacggta ccagtgacgg ccggatgtcc gtgacggtat gtcctgcttc ttttgcaaaa
     4261 cggtaaccat cccctgtaga gccggtcgtc tgataggaaa atccgcctgt cgcaatgatc
     4321 actgcatctg ccggcattgt ggttccatct gtcagcttta cgcctgtgac aatgttttcc
     4381 ggtgcatctt ctccggatga ttccataagc agactttgta cctgtgtatg cagcattact
     4441 tttacttttt tctctttcag cactttctgc aatgttgcga tcacatccga ggaatgatcc
     4501 gaaacaggaa atacccggtt gccacgctct gtttttgtcc tcagtccgtt tctctcaaaa
     4561 aaatcaatga ctctttgatt gtcatacgaa taaaaggcgc tatataagaa ctttgcattg
     4621 gtcataacat ttgcaaagag attatccata tctcccgcat tggtaatatt gcatcgtccc
     4681 tttccggtaa tgaaaagttt tttcccaagt ttttcattct tttcaagcag aataacctga
     4741 ctgccggttt ccgctgcggc gatcgcagca aacattccag ccggtccccc gcctattaca
     4801 atgattttat tcatgaaaat cgctgtctcc tatttttgca taacgcattt ttatggaatc
     4861 gtcaatcgca ttgatctcat cattttcata gacctgatac tcatcccaga ttccttctaa
     4921 catttctaat gtcttcgcaa catctctctg ttttttcata cagagtgcca cgatcagggc
     4981 attgatcacg ctgagtggtg caaccagtga atccacaata gacgccatat cactgtctgc
     5041 gatcagatta caggacgaat acaaattcat cggtgaatgc acactgtctg ttaatgtaat
     5101 cacttttgca ctgcggttgt tggcaaactc catagccttt aacgtccgca tggaatatct
     5161 cggaaaactg attccgataa ttacatcttc cttaccaata cgaaccattt gttcaaaaat
     5221 ttcactggaa ctgctcgtct gtatcagacg tacattttca aacatcaaag taaaataaaa
     5281 tgccataaac gacgcaagcg gcgcacagct tctgattcca ataatataaa tatgtttcgc
     5341 attcaaaatg gtatctactg ccatctcaaa tgccgcctga tctatttttt ccaatgtgct
     5401 gttgattttt tccgcatctg actttaaaac agattctaaa atttttgact ggctgattct
     5461 gccataagta acttccatac gctgaatgga gtttaatttg ttgcgtacca gttcttctaa
     5521 ggcactctga aattcaggat atccccggta tccaagatgc atggcaaagc gcacaaccgt
     5581 ggattcgctg actccgacca cctcacctaa ttttgccgcc gtcaaaaata ctgccttatc
     5641 atagttatct gtgatatagg tggcaagcag tttctgtccc ttgctcaatt tactgtatga
     5701 ctcgttgatc cgattactca aatcattctt actgcccata acccctcgtt cctgtcattt
     5761 tatgacaccg tctgcaattt atgatgtgcc tttgcacacc aacatttcta ttatatcaaa
     5821 acttttcctt tttgtcagct ttgaatcatt ttcattctgt aaaattcacc ttttcgtgcc
     5881 atcagctcct caaacgtacc atattccaca caatgtccgt ccgcaagaac ggcaatctta
     5941 tctgcatcac gaattgttga cagccggtgt gccacaataa atgtcgtcct ccccttcgtc
     6001 agattttcca aagcttcctg tatcagtttt tcagaaatac tgtctaaagc agacgtagcc
     6061 tcatcgagta cgatcacctc cggatcacgg atcagtgctc gcgcaatcgc aatgcgctgt
     6121 ctttgtccac cggaaagttt tcctccatgt tctcctacca tggtatcaac cccatttgga
     6181 agactctcca tcagatccgt aagatttgcc gcctttatga cacgttctaa ttcttcgtcc
     6241 gaaacatgtt cgtttccgta agtaatgttt tcacgtatag tccctgaaaa taatatggat
     6301 gtctgtggta caacggcaag atgttttctg tatgtacgca gatctatttt cctcatatca
     6361 ttaccatcta aaaggacctt ccctccgtcc gccaaatgaa agccgatcac aagatttaac
     6421 acagtcgatt ttcctgcacc tgactccccg actaatgcga tcgtctcccc ctgttttaca
     6481 tgcaggttca ggtgatttaa caccggtttg tcactgtttt tataatgaaa ggaaacatct
     6541 tcaaaatcaa atatgccagt tacgtcctct aactgctttt tcccctcatt ctgctccaca
     6601 tcctctgaga ggagcacctc accaatggaa ttgacagatt caatgccttt cgcgattgtc
     6661 ggaagcaatg taacgattgc agacacctga ttgaccaccg ttgcaaaata actctggtaa
     6721 agtgtgatat ctcccgccat aatgcgtcca cgcaacgcaa gatagccggt aaatgccaga
     6781 cagacgacct gaaacacctg gaataccgcc catccgactg aaccaaataa tgcctgtacc
     6841 agatccagtt tatatccctt ttccgccact gtaaaaagct gtccgctcat cttatgtact
     6901 tcttcgtcct ccaatgcgtg tgcccttgtc accgggacaa gttccaccat ttccatcaca
     6961 cgcgcagatg tttcttccat ttcttttcga aattccgtat ttcttttttt catgaccgag
     7021 cggaacgaaa ccatcgtgat tgccgcaacc ggagttgtca acagaaaaaa tacaaaaacg
     7081 atcttacttt ttgatgctgt gaccaccagc gcaaccccga tattcagtgc aatatttaaa
     7141 atgcttaaga acatctgtgt ggaaagtgtc tccaccgcct ccacatcacg cataatctta
     7201 gactgcagcc ttccagactg tgtctccaca tggtaggcga tcgacaactg ctgaagtttc
     7261 cggatcaatg ccttacgaag tcctgtttct gcgtaacgtg ttgcaaggct tttatatgat
     7321 gtatacagat aattcattgg tatattaagt gcgatcaaac caatctcaag ggctgcactg
     7381 atccagatat ttctcacggt atcaggattc ttctgtgtca catcattgat gatatttgca
     7441 gttatgattg gaagtaccca cacacatgca tgctttataa aaaaacagat aactgccata
     7501 acaaatttat gataatttcc tttgtacagt gctatcagaa tccgtatcgg atgaccttta
     7561 tatctgcgat aactttctat aaaccagttt tctgtatcta tgccattttt cggcgacgtt
     7621 ttccgttcaa aattttccat tttcttatat cctttatcat ttataggatg attctaattc
     7681 ttttctttgt aaaaagcaat atttcagcaa aacaaaaaat gccacagcag catcctaaaa
     7741 tactgccatg gcatttcatc aatcatattc caattatacc ggatatgcac cattctttgt
     7801 atctgcaatt gttgcatcta cttttttctg ctgtgcttca cggtatttga agaactcagt
     7861 tgcaacctgt gggaacaatg cgtaagataa tacatcttca tcctgctgtt tccactgttt
     7921 catctcagct tcaatcttgt caagctctgg ctctaacaga tctgccggac gacaggtaat
     7981 tgcattcttc ttctcatcgc ctaatacttt gtcaacaact tccggattga acggttttac
     8041 agtctgaccg tattttccaa ggagaacatc tttcgtctct ttggtcgcta ctttgtaacg
     8101 ctcacccatt aatacgttga atacagcctg tgtaccaacg atctgtgagg aaggtgtaac
     8161 aagcggcggc tcaccaagat ctttacgaac acgcggtact tctgcaagta cttcctcgta
     8221 tttgtcctct ttcccctgct cttttaactg ggagatcagg ttggataaca taccacccgg
     8281 tacctgatat aataaagtct tgatgtttac acctaatact ttcgggttca tcagaccact
     8341 ctctaatgct tcctctctca tcgggcggaa gtaatcagcg atctcagcaa gtttgttctg
     8401 gtctaaaccg gtatcaaact ctgttccctt gaatgcctct accataactt ctgtagccgg
     8461 ctgggatgtt ccaagtgcaa atggagacat tgcagtatcg atgatatcac atcctgcctc
     8521 tactgctttc atgtatgtca tggaagcaac acctgatgta tagtgtgtat gtaactctaa
     8581 cgggatatcg atcacttctt tgatcgcacg taccagctcg tctgctttct gtggaactaa
     8641 aagtcctgcc atatctttga tacatacaga gtcagctccc atatcctcta ctctttttgc
     8701 catatctgtc cagtaatcta aggtataagc atcaccgagt gtataagata aagccacctg
     8761 tgcatgtcct ttttctttgt tacatgcgct tactgctgtc tgaagattgc gaagatcatt
     8821 cagacagtca aaaatacgga tgatatcaat tccgtttgcg atggatttct gtacgaaata
     8881 ctctactaca tcatcagcat atggacggta tcctaagata ttctgtccac ggaataacat
     8941 ctgtaatttc gtatttttaa aaccatctct taatttacga agacgatccc atggatcctc
     9001 ttttaagaaa cgaagggatg catcgaaagt agcgcctccc cagcactcaa cagcatagta
     9061 tccaaccttg tccatcttat ctacgattgg aagcatctgc tctgttgtca ttcttgttgc
     9121 gatcagagac tgatgtgcat cacgcagtac tgtctctgtt atttttaaag gttttttaac
     9181 aacttcagcc attttttcct ccttatacag cgaacctgtt tttgttctgc cgtctgatta
     9241 aattccaaag attgccatga atacaccggc tgctactgct gtaccgataa caccggcaac
     9301 gtttggtccc attgcatgca taagtaaaaa gttcgtagga tcttcctctg caccaacttt
     9361 ctgtgataca cgcgcagcca taggaactgc ggatacaccg gcagaaccga tgagtgggtt
     9421 gatcttgcct tttgtaatga agcaaagtaa tttaccgaac aatactccgg ctgctgtacc
     9481 aaacataaat gcaatcagtc caagtgcaac gatctttaaa gttgttgcat ttaagaaagc
     9541 ctctgcactt gtggatgcac caacggatgt accaagtaag ataactacga tatacatcaa
     9601 tgcattagat gctgtctcag ataactgacg aaccacacca cactcacgga acaggttacc
     9661 gagcattaac ataccaacga gcggggctgt tgtcggaagg atcagacata caacaacggt
     9721 taccacgatt gggaataaga ttttctcaag tttggatacc ggacgtaagt tctgcatctt
     9781 gatcgcacgt tcttttttcg ttgtaaataa cttcataatt ggcggctgaa tgatcggcac
     9841 cagtgccatg taagaatatg ctgctacagc gatcggtccc ataaggccgg actgtccaag
     9901 ttttccagca aggaaaatgg aagtaggacc atctgcacca ccgatgatag aaacggctgc
     9961 tgctgcttta tcattgaatc ccatcaggat tgcaaggaaa tatgcgccga aaataccaaa
    10021 ctgtgctgct gctcctaaaa ggaagctgat cgggtttgcg atcagaggtc caaaatcggt
    10081 catcgcacca acgccaagga aaataaggga tggcaggatt gaccattcat ctaaggtata
    10141 aaaataatgg aataaaccac cgacaccgtt actcatctgc tccggagctg caaagatatc
    10201 cggataaatg tttaccagaa gcataccaaa tgcgatcgga acgagtaaca acggttcaaa
    10261 cccttttgca atcgccagat acaggaaaat acatgcaact aagatcatta cgaaatttcc
    10321 ccatgtcagg ttaaaaaagg cagtctgatg aaggaggttg cccattgtct cagtaaaata
    10381 actcattgtt atcctcctaa aattagttgt ttaaagttgc cagtaatgca cctgcttcta
    10441 ccatgtcacc aacacttacg ttgatgcttg ctactgtacc atcttcggta gcaacaaccg
    10501 gtgtctccat tttcatgatt tcaagaacta agattgtgtc acctttcttt acagatgcgc
    10561 caacagaaga ctcgatctta aatacttttc ctgctgcacc tgcttcgatc tttacgttac
    10621 ctgcgccacc tgccggtgct gctgccttcg gagctgctgc cggagccgga gctgctgcac
    10681 gtctcggtgc tgctgccggt gcacttacag caccattctc ttctacagta acatcataaa
    10741 catttccatt tacggtaatt gtatagcttt tcattgaatc atcctcctgt gatcattact
    10801 tttttacgac atatatttat tataacttgt ctgtttcgcc tatcttctat ggatagaacg
    10861 tactacgaat ccatctgctg atgttccttc tgccgctgcg attgctgcag aaataactgc
    10921 aaccagttct aaatcatcag taagctggga tgtctcctca cgctgctcga tctgttctac
    10981 aaccggatct gccacatctt tcttcgcacc agcatttgct tttttgttct gtaaatacgg
    11041 aatcacttta aagcagctga tgatcagact gatcaggata agaactacaa atacggttcc
    11101 cattcccatc aatgtattca taccggcttt tcccattttc tcgccaagtg aatacacaag
    11161 atctgcactt gcatctgtaa gttccggtgc ttctgtctcg taattgtatt catatacata
    11221 agaaacaact acatctctgt ctgagaaatg taaaacctgg tctgcagtca cagtcttctg
    11281 tgcttttgtc acagtaagat ctccaagtcc ctgataggaa cccagatctg aaactgtttc
    11341 accccaggat gtcagtaagt gggcaaatgc atccattccg tttgagtcat aatattctgc
    11401 accactctgt atatcttcat ctgaaaacga aacaagcgca gatactgtct gctccatgtt
    11461 atcctggata tcagaataac tcataccaaa ataatcaacg ctcttaggat ccgttccaca
    11521 tgctgtcatt gccagaacca taaagcaaag acaaagcata agagataatt ttttcttcat
    11581 aacttcacct ttctattttg ttccatgttt cttgtccggt acacctgcac attttgtgta
    11641 taataattca aatgcatcta caaggtattt tctggtgtct gccggatcta aaataagatc
    11701 tacataacca cgtcttgctg cagtcataac acttgactgt aatgcatcat attcttttgc
    11761 ttttgctgcg agttcatctg cagatgcatc tgcgtacatg atctttgctg caagctcgcc
    11821 atccatcata ccgatctttg catcttccca tgcatatgta aagtctgctc cgattgcttt
    11881 ggagttcatt gtcacataag cgcttccgat tgcatttccg gtgatcaggt ttactttcgg
    11941 gcaggttgca tcagcgaatg ccattgtcat gcgtgcaagt gcttttgcaa gtcctttttc
    12001 tgcacagaca gtagctgcat aaccttttac gtttgttaaa gacaataccg ggatctcgaa
    12061 cgcatcacag aagttaacga actctgctgc cttgttgcat cctcttgctg tcagagctcc
    12121 ggagaactcc tctgcttttt tgccctcttc atcgtaaact tctgagcagt ttgcaacagc
    12181 gccgactgtc attccgttta actggataaa tccggttacc atatcttttg catagttttt
    12241 ctttgtttca aagaatacat gtccgtctga gatctcactt aataaatatc ttggatcgcc
    12301 tttcatggct gccatgttct cacatgcacg gttcaaatca tcctgacact cagatgtgta
    12361 tacatctcct tcattattta aaggaaggac gcttactaac tcgcggatct ctgcaatgat
    12421 ctcatcctct gttccaacag catcgataca accgtttttc tcactctgga actctgcgga
    12481 agaagtatcg catttttcaa tacggttacc ctcgatcgca ttcggggaat tgatgaacat
    12541 ttttcctttg ctctccataa atgcgaaatc agataatgca ggaactactg caagtccacc
    12601 gccacagctt ccgaaaatag cggaaatctg cggaacaacg ccggatgctg caacctcctt
    12661 tgcgtagatc tcaccaaatc cgtttaacgc atccacagat tcctgtaaac gcattccggc
    12721 gcaatcgata aatccgatca ccggtgctcc cattttcatt gccatgtcat atacggctgc
    12781 aatcttcttt gcatgcatct ctccgatagt accgtttaat acagctgcat tctggctgta
    12841 tacaaatacc agattgccat ccaccagacc atgtccggta attacaccat cggacggtgt
    12901 atctgtgtct gcaagattaa agtctgtatt tcttgcggtt acgagagaac cgatttccat
    12961 gaaactgttc tcatcgacta acttggtaat acgctgcatt gccaagctat cattactact
    13021 attcatcctt tttgccctcc atctataaag tttgttacca catcttttga catggtacat
    13081 agtgaataat gtaaaaatat aacaaattcc gctaggataa attatagatg gtcagtgaca
    13141 aattttcaag agaattgtta attttttgac agtttttttt tgcatacaag gaatttaggg
    13201 cttttacatt ggaaataatt ctgctgtttt ttttacacac cagcaaaaat cgattctttt
    13261 taccgtattc ttcactgtga ccacacgttt tgccagaacc tcatctccca gaaggtatgt
    13321 tatctcaccg ataaaatctc cttccgttac cggtgcataa agtttccggg ataattgata
    13381 ctctatgtgt acttcctggt ctttttcgat caatagttcc acattttctt tcaccggcgc
    13441 aacttcaagt tctgttgtta cctcttcacc gatctttgtg ccctgtccgt ccaccacctg
    13501 taccggagca tattcccctg cgtccagttc aatctcatcc agacttattt tccggaaccg
    13561 ggaaattcca tactgcataa gtttttttgt atctgcccac ttatatgttt tattattcgg
    13621 ccacccgcag gcaagcagtg caacgataaa agttctgtca tcacgtttta atgccccgac
    13681 ataacaatat cccgcattac cggtaaaacc ggtcttgcct gacaatgccc cgtccatcat
    13741 ctgcaaaaat gcattatgat tacagcaggt gtaactgttt ttaccatcta tatcagaaaa
    13801 ctgatactgt ccttcccttg tgattgtaag aaattgctct gccatttctg atgttttgat
    13861 gcagtaccgc atgatcaaag aaagatctgc cgctgttgtg tgatgaaagc cattttcatt
    13921 tttggcatcc agtccgttcg gtgtgataaa ataactgtcc tcacagccga tctcctctgc
    13981 tttatcgttc ataagttttg caaaatcacc cgtcgtgcct gcaatgtgtt ctgcaatcgc
    14041 cacagcgcag tcattataag attccaacat cagtccgtac agcagatctt tcagataaaa
    14101 cttctgcccc tcccgcatac ccagatgaac tttcggctgt gacgctgcaa gcgtactcac
    14161 ggtcacttcg ctgtccaggt cgcagttttc cagtgcaatg atacatgtca gtattttggt
    14221 cgtactggca ttcgccatcg cctggtgccc gtttttttca tacaggatac gcccggaatc
    14281 cgcatccata agcacagctg cttttgcata cagggaattt tgatccggct tttctatcac
    14341 tttctccatc cgcacatttt ctttttgatc aaaagcctcc acgatctgta tcccatatcc
    14401 tgttaagatc acagtgacaa ggatccatgc cagcagtttt ttccacatac accagactcc
    14461 aaaaaagcat ttcatcaatc cttatgtata taatacgcaa aaaatgctca ttttttgtga
    14521 aaaaaaagca tacgaaacca gatcagatat ccagtttcat atgcatttcc gcttccgctt
    14581 cctgtttgaa ttcttctacc tggaccggac ttaacacggg aagttcatcg attgactgaa
    14641 cgccaaaact ccttaagaat tcctccgttg tgccaaaaag cagcgggcgt cccggcgcat
    14701 ccagccttcc aagttcacat accagattgt actccaccag cttgtttacc gcatgatcgc
    14761 aggaaacacc tctgatcttt tcaatttccg cctttgtaat cggctgcttg taggcaatga
    14821 tcgaaagggt ttcaagcaaa acgtcggtaa gcacatgctt tttcggctgc tttgcgattt
    14881 tcaccagata ttcatacatt tcgcccttcg tacacatctg ataagaaccg tccagttcca
    14941 tgatcttaac gccgacgcca tcatcctcat agcgctgcat cagatgttct atgatctttt
    15001 ttgtccgttc tgtatcaagt tccagtgttt ttgctatacg ctctaattcc acagactctc
    15061 ccattgtaaa caggatcgcc tcaacgattg cctcatattt tttttcttcc ataccaaccc
    15121 tctattccgg tgtgtaaaaa ttccacacag atcccatttc atttctgctg tcacacagct
    15181 aggccgcaat ttttgattca atttttatat catcaaacgt gtattcctgg gaaacaacga
    15241 tctttcccat cttcatcagc tctaatattg ccagaaatgt cacaaccact tccattttcc
    15301 cggactgtgc ttctaaaaga ctccgaaacg aaaaatgtcc gtgatgcaga ctgtattctt
    15361 ccacatatgt catcttatca gaaagtgaca cttcctcttt ctcgattctt ccaaacttcg
    15421 aacggaccgg atcgatctta tccgcctgtt tctttatgat ggactgaaaa atatcattca
    15481 gcctcgcaag tgttaccccg gacatcagtt cattcacatc aaccggttct tcatatgcaa
    15541 gaacttcggg tgggattgtc ggtgctttaa accatacttt ttccgcatca atctgacggt
    15601 ccctgagttc atatgccata catttataca ttttatattc caacagctgc tgcacaagtt
    15661 ccgctctcgg atcttcttct tcctcatcct cgctttcttt tgcagggagc agcatttttg
    15721 atttgatatc aagcagtgtc gccgccatca cgagaaattc gctcatcaca tttaagtcct
    15781 gtctgcgcat ttcggcaata tattccatat actggtttgt gatctccacg attggaatat
    15841 catatatatt gactttattt ttttctaaca gatgtaaaag cagatctaac ggcccctcaa
    15901 acacctgaag ttttacagtt aattccatct atgtcatacc ctctcattcc acaaatattg
    15961 attttaccgt ggattcccgc aaaattcaag atttttatgc ataatgtaca tccttcgtat
    16021 ctaaaataaa ttataacaga accctacgga gggcatattc ttgaaattca tggtttccat
    16081 tctgctcggt ctcaatctcc ttgtgcaggg cacggtactt cctgcatctt cctgtttcat
    16141 tccgaatgta accatccccc tgtctcctgc tgcccagaca gatactgcac ctgctgcaga
    16201 cttaaatatc tccgcaccaa gcgccatttt gatggaggct tccaccggtg ccgtcgtcta
    16261 cgaaaaaaat tcccacgagg caaggcatcc ggcaagtgtc accaagatta tgacgctgct
    16321 tctgattttt gatgcactct catccaaaca gatttcctta gatgacacgg tgaccgtctc
    16381 cgaatatgca gcaagcatgg gcggttccca ggtgttttta gaaccgggtg aaacccagac
    16441 agtcgaaacg atgatcaaat gtatcagtgt tgcgagcgcc aatgacgcct gtgttgccat
    16501 ggcagaacat gttgccggtt ccgaatcaga atttgtccgc atgatgaacg aacgcgcaaa
    16561 aggactcggt atgaatgaca ccaatttcgt caactgctgt ggtttagatg ccgacggaca
    16621 tatgaccagc gccaatgaca ttgcactgat gtcgcgcgaa ctgatcacaa aatacccgaa
    16681 aatccatgat tactgcacaa tctggatgga aaatatcacc cacactaccg caaaaggttc
    16741 ctcggagttc ggtctgacga acaccaataa gctgatcaaa cattaccagt atgccaccgg
    16801 cttaaaaacc ggatttacca acactgccat gtactgtatt tccgcaaccg ccaaaaaaga
    16861 tgatatggaa ctgatcgccg tcatcatggg ggctcctgat atcaagtcac gctctgcgga
    16921 tgccacgact cttttgaatt atgggtttgg gaaatgcagg atttactgtg acagccacga
    16981 agataagtta gacgatctcc cggttgaaaa aggccttgcg gattctgtag gcatcattta
    17041 ccaaagacct tttcaataca tgacaacaga cggaagtgat cttaccggca ttaccaaaag
    17101 catcgaactg ccggaaaatg tgacagcacc agtaaaaaaa ggaaacactg ccgggaaggc
    17161 ggtctattct ctaaatggaa cgccgatcgg cagtgtcaat attgtatatg cggatacagt
    17221 cgatgctgca gattataaag attatttttg ccgcaccctg ttatattttg ttccttaaaa
    17281 atacagagtc cggtgtatca ctgatttgat gtcatgaaac attctgttat tacatatcac
    17341 tgatctgatg gtgtggaaca tttgttctca tattataaca acggtgcaaa cagacgcatc
    17401 aggctctgaa ccatacgtac cggaagtctt cgtctgcggc agaatgaaac atccatctcc
    17461 tccgactctt caaatgtcct gaggcagtct tcctttacct gcatgactgc cttagaccgg
    17521 tacataaata caccacattc aaagtgtaaa aacagactcc ggtagtcaag gtttacactg
    17581 ccgaccgtcg cgatctcatc gtcacagaca aaacattttg catggataaa tcccggtgta
    17641 tactgaaaaa tcttcacacc attctttaaa agcggttcat aataagactg tgttaaaaga
    17701 tatactgcct ttttatccgg cacacccggt gtcacgatcc ttacatccac accgctcttt
    17761 gctgcatttg agagacagat cagcatttcg tgatcgatga tcagatatgg tgtaaaaata
    17821 tacacatagt ttttcgcacg gtttatgata ttcagataaa tattttctcc gacgttttca
    17881 ttatcgagcg gactgtcacc atacggctgt acaaagccat cggaggtaaa ttctttctcc
    17941 ctgtaaacag acggcaggaa tctgctgtaa tcttccgtgg aacggttgat ataattccac
    18001 atttccagaa acattgccgt aaggctccag actgcctctc cctcaatccg cactccggta
    18061 tccttccagt atccaaacct tttgacttta ttgatatatt catcggcaag attgataccg
    18121 cctgtaaatc caatataccc atccaccaca aaaattttac ggtgatcgcg gttgttcatc
    18181 accacagaga tcagtggttt aaacggattg aatgtcacac agggaatccc tctctcctgc
    18241 agctttttat aatatccaaa agaaatagaa ttgatgctgc cgacatcatc atagataaag
    18301 cgcacatcca ctccggcctt tgccttttcc tcaagaatat caaggatcgt attgaacata
    18361 tatccttctt caatgataaa atactcgaga aatataaaat gttttgcacc gcgcagtgcc
    18421 tctaacatat ccgggaacat ttcttccccg cagctgtaat attttgtctg cgtgttctga
    18481 tataatggaa atcccgccca tttatcaata taagatgact gcagatatgc tgaccggctt
    18541 tctttttcta agcctttctc cactgcgcta tctctctgaa acaatgcttc cacctgacgg
    18601 ttgacagcat ccattctctc tcttgtatgt ttggtcagac cggatcttcc aaataagaaa
    18661 tataccataa gtccaaaaat cggcgacaat aagattaaaa acgtccacga gagtttattc
    18721 gccggatttg tccatttatt gacgattaca agcacaacaa tgattgctat cacacgcaca
    18781 agcaaattga catacgtaaa cttgtaactg agctgccaca atacgacaca cagccataac
    18841 acctgtaaaa tgattgccat ggcaaccaca aaaaatcttc caaatatgag atgtaatatt
    18901 ttcttcatac aaatctccat tctccctgca cgcttttcaa tgaaagcaac gttttcatct
    18961 gcatcacaag tttgtgccac agtacaaaca tgtgcttatt gtaataattt tcctctcaaa
    19021 agtcaacgca cgagatgatc cacatgtatc atcccccatc cgatcctgcc aagctgcgca
    19081 cttctcggat atgctctctc ataaaggcgc agcttcattt ctgccggagt aaatgatgga
    19141 tacttctcaa atgcaagggc aagcgcccct gagacaaccg gtgctgccat ggaagttccg
    19201 ctttttacct gatatccgct tttatccttg ctgcagcttg taataccggt tccgggtgcg
    19261 aggatttccg gctttacgat gcagcatgca gtcggccccc tgccgctgta tccggttttt
    19321 aaaacttttc tcccacggtc ataggtatca tcatcactgc ttccgaccgt cagtactttt
    19381 cttgaaatac ccggaatcgt caccgtattt tcttttggtc cgttatttcc tgcagcggca
    19441 acgaccatga tccctgcatc ccacaattca tcgatcgcat ataaaagctt tctctgctcc
    19501 tccacacctg cgcccggtaa cattcctacc gatatattta atatcttaat atgataacgt
    19561 tccctgttct ctttgaccca catcactgca tcaagtactt ttttcgtatt tccatttcca
    19621 ttttcatcta aaacctttaa catgataatc ctgcattttg gtgcaactcc actgtatatc
    19681 cgaaccttat gtgcagtatc tttcagatac tgctcagaca tttttccgtt tcccgcaata
    19741 atccccgaaa catgggtgcc gtgaccatta tcatcataca tttcctttct cccataacaa
    19801 aaatcatgaa aatatatgat tctgtcctca aaatccggat gtgcaacaat accggtatcc
    19861 atcactgcaa cggtaacatt ctgtccgcta agtcctgatc tgtatgcata atccgtgtga
    19921 atcatcttct tcacccgatc catagtctct cccattctgt caaagaactt ccatattatt
    19981 atatgaagaa atttattttc tgctaaaaat gataaaaaaa tgttaaattt ttctgaatat
    20041 tcagaagaat gtttgacact tggcatgatt ttccttataa taaataatag ttaattagtg
    20101 aactattttg gttcgcttta aaatcaaaaa agaaagtagt gtgatgccat cttgaacaaa
    20161 aaactcaaag aaaaatttga cgaatccgta aatgcagtcc tgccgatcac ggtgatcgtg
    20221 ctcctgcttt ccatttttgt tgttcccatg gaaaccggaa cgatcgccct gttcttagtc
    20281 ggtgcattta tgctgatcat cggcatggct tttttccagc tcggtgcaga aactgccatg
    20341 acacctctcg gcgaaggcgt tggttcttcc attatgaaaa caagaaagct tcctgtttta
    20401 atcggcgtat gctttctgat gggtattatc ataaccctcg cagaacccga tcttcaggtt
    20461 cttgcaaatc aggttccttc tattccgaac aataccctga tctttacggt tgcacttggt
    20521 gtcggcgtat tcttagtgat cgccgtactc cgtattctct ttcggatcag tcttccagtt
    20581 cttttgtgca ttttttatat tgcactgttt tttctttctt tcgcggctcc tgctgatttt
    20641 attgcagtcg catttgactc cggcggcgtg acgacaggtc ccatgacagt tccctttatt
    20701 atggcgatcg gtgttggtct ctccgcaacc agaaacgata aaaacggttc gagtgacagt
    20761 tttggtctga tttctttttg cagtgtaggt cctgttttaa tggtccttct gcttggcatt
    20821 ttttatcatc caactggtgc cgcatacaat gagacaacaa tcccggacgt aatcacgatg
    20881 caggacgtga tccgcgaatt tgtacatatg ataccggatt atgcaaaaga ggttctgctg
    20941 tccatccttc cggtaatttt cgtatttctg atcttccagc ttatttccag acgttatcac
    21001 aagccacagg tgatcaaaat gatcatcggt ttactctaca cgatcatcgg tctgatcctt
    21061 ttcttaaccg gtgtaaacgt cggatttgct cctgttggaa gtcttcttgg aagcagtctt
    21121 gccggccagc cgtggaaatg gattttaatc ccgatcggtg ccttgatcgg ttactatatc
    21181 gtaaaagcag agcctgcggt ccaggtatta aaccgtcagg ttgaggacgt cacaaacggc
    21241 tctatttcca gagataccat gaatttaagc ctgtcgatcg gtgtatccgc atccgttgca
    21301 cttgcattgc ttcgtgttct taccggttta aacatttact ggcttttaat cccgggatac
    21361 ctgattgcac tgattctgac aagatttgta ccaaaagtat ttgtcggcat tgccttcgac
    21421 tccggcggtg ttgcgagtgg tcctatgact tccacttttc tgctcccgct tgccatgggt
    21481 gcatgtaccg cgatcggagg aaatgtagtc acagatgctt tcggagttgt tgcgatggtt
    21541 gccatggcac cacttattgc agttcaggtc atgggtgtct cctataatat gaaattaaag
    21601 aaagcaagta cccctgccgc cgccatcatt ggcattgacg acaatgaaat tctggatttt
    21661 gaggaggatt tttaacgatg caggaacaga aaaaacgaga agcttaccgc tgccttgtaa
    21721 ttatcacaga ctcccatatc agagagcaat tatgcgaatt tttagcagat tcccatatac
    21781 cggtctacta tcagatgcat gggatcggca cagccagttc agaatggtta gaattatgcg
    21841 gtcttggaag tatccagaaa agtatcacac tctgttttat tccaaacgga cgcaaaaaaa
    21901 ttctgctcgc tgaaatgaat caggcattga gccttcataa aaaaggaacc ggtattgccg
    21961 tcagcattcc catgaacggt atgcagggat ttctatataa acttttaaac gagcacaccg
    22021 cagaatcaga cggcgaagaa gttgaaaagg aagtgaaaaa gatgagtgaa ccaattacac
    22081 atgctatgat acttgtaaca atcaatcagg gatacagtga cgctgtcatg aacaccgcgc
    22141 gcgctgccgg tgcaaccgga ggcacgatct taaaaggtct gcgctgcagt cccggaaaat
    22201 cggctgtcat cttcggcatc acgatccagg aagaacagga aatcgtcgca atcgttgtac
    22261 caaaagataa aaaaacagag atcatgcagg cgatcagctc tgctcatgga atggactctc
    22321 ctgcccatgg tgttgccttt tccctgccag tggacggaat tatgggattg taatgccgat
    22381 gaggccattc tattgtcagg tattacaaaa aagaactgca cgttaataac tatcattaac
    22441 atacagttct tttttcaaat ccatatatct tgtatataga ttatttataa tttttaaact
    22501 atttgttttt tcttatgcct ctgccggaac atccttcata gagaagctga tgcgtcccat
    22561 cttgtctttt ccaaggcaga caacttttac tttatctcct aatgtcagga catcctccac
    22621 acgattgata cgctctttgg aaatcttgga aatatgaacc attccctctt tacccggagc
    22681 aaattcaaca aatgcgccaa attctttgat gcttacaaca gtaccagtaa agatctgtcc
    22741 ctctgcaaag tcagtggtga taatcttgat catttcgatt gctttgttca tcatctctgc
    22801 gtctgtgcca catacagata cagcaccgtc atcggtaatg tcgatcttaa cgcctgtgcg
    22861 gtcaatgatc tcgttgatcg tctttcctct ctgtccgact acatcaccga tcttgtccgg
    22921 attgatctgg atctgaacga tcttcggtgc gaatgtgctg acttcttttc tcggctcctc
    22981 gattgctttt gacataacct catccatgat gtagattctt gcctct
//
