LOCUS       c00020_gnlPro..        12776 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BMGDPBIK_20.
ACCESSION   c00020_gnlPro..
VERSION     c00020_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 23:59:15
            Original ID  :: gnl|Prokka|BMGDPBIK_20
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 17752
            Orig. end    :: 30528
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12776
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[27752:29918]"
                     /cutoff="10000"
                     /detection_rule="(not (EC1_2-faecali or baiH or baiCD or
                     ECH1_Enoyl_CoA_DH1 or ECH1_Enoyl_CoA_DH2 or
                     ECH1_Enoyl_CoA_DH3 or ECH1_Enoyl_CoA_DH4 or POR or POR_N or
                     PFOR_II) and minimum(4, [AcetylCoA_hyd_C, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, EC1_2-faecali, ECH1_8_CARC, ECH_1, ECH_2,
                     HBT, HCDH, HCDH_N, Thiolase_C, Thiolase_N,
                     ketoacyl-synt]))"
                     /neighbourhood="10000"
                     /product="fatty_acids-unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12166
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(not (EC1_2-faecali or baiH or baiCD or
                     ECH1_Enoyl_CoA_DH1 or ECH1_Enoyl_CoA_DH2 or
                     ECH1_Enoyl_CoA_DH3 or ECH1_Enoyl_CoA_DH4 or POR or POR_N or
                     PFOR_II) and minimum(4, [AcetylCoA_hyd_C, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, EC1_2-faecali, ECH1_8_CARC, ECH_1, ECH_2,
                     HBT, HCDH, HCDH_N, Thiolase_C, Thiolase_N,
                     ketoacyl-synt]))"
                     /neighbourhood="10000"
                     /product="fatty_acids-unassigned"
                     /protocluster_number="1"
     cand_cluster    1..12776
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(not (EC1_2-faecali or baiH or baiCD or
                     ECH1_Enoyl_CoA_DH1 or ECH1_Enoyl_CoA_DH2 or
                     ECH1_Enoyl_CoA_DH3 or ECH1_Enoyl_CoA_DH4 or POR or POR_N or
                     PFOR_II) and minimum(4, [AcetylCoA_hyd_C, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, EC1_2-faecali, ECH1_8_CARC, ECH_1, ECH_2,
                     HBT, HCDH, HCDH_N, Thiolase_C, Thiolase_N,
                     ketoacyl-synt]))"
                     /kind="single"
                     /product="fatty_acids-unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12776
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="fatty_acids-unassigned"
                     /region_number="1"
                     /rules="(not (EC1_2-faecali or baiH or baiCD or
                     ECH1_Enoyl_CoA_DH1 or ECH1_Enoyl_CoA_DH2 or
                     ECH1_Enoyl_CoA_DH3 or ECH1_Enoyl_CoA_DH4 or POR or POR_N or
                     PFOR_II) and minimum(4, [AcetylCoA_hyd_C, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, EC1_2-faecali, ECH1_8_CARC, ECH_1, ECH_2,
                     HBT, HCDH, HCDH_N, Thiolase_C, Thiolase_N,
                     ketoacyl-synt]))"
                     /tool="gutsmash"
     CDS             1038..1388
                     /locus_tag="ctg20_19"
                     /transl_table=11
                     /translation="MTLNECYEEMGADLHEVLRRLKTEERIGKFLKLILTDTNYESLCK
                     ALEEKNYEQAFTHIHNLKGLAMNLGLTPLLVPAQELCEELRDGEPERELKPLLDEVAAA
                     YQKVLGIVERLD"
     CDS             1533..2153
                     /locus_tag="ctg20_20"
                     /transl_table=11
                     /translation="VQVILLIIAVSVDVFVACVACGSEQIKIGSAAALCISTVCSGILG
                     ISLYAGMALQGVLLKKYALYLSFFGLLAVGIFKLTEYAIRKYIERHKFLCKKVKISFSQ
                     LSFILSIYNNPVMADRDHSATMSCLEAVFFALAMSLDGMFGGLGAGFTGKNIFLTVLGS
                     FVVSFCAVLCGCRIGMQASKRWKADVSWLGGVLFVILAFQKII"
     CDS             2371..3570
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_21"
                     /sec_met_domain="GATase (E-value: 5.7e-48, bitscore: 154.1,
                     seeds: 97, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHFLQFRKKTIGTNKGKFSQGTVWMEKEEKRRRFFFWKKSERTG
                     KRMKAHLILEDGNVFTGTSIGSTREVISEIVFNTSMTGYLEVLTDPSYAGQAVVMTYPL
                     IGNYGITPDMESGRPWPDGYIVRELSRMPSNFREEGTIQDFLTKYDIPGIAGIDTRALT
                     KILREKGTMNGMITTNNNYNIEEIIPRLKAYTTGNVVDKVTCSEKRVLKGNGKRVALLD
                     LGAKNNIAQSLNKRGCEVTIYPAHTTAEEILATNPDGIMLSNGPGDPKECKEIIAEIKK
                     LYDSDTPIFAICLGHQLMALATGADTHKMKYGHRGGNHPVKDLETGRVYISSQNHGYVV
                     DTDTLDPKIAKPAFVNVNDGTNEGLSYVGKNIFTVQFHPEACPGPQDSAYLFDRFISMM
                     "
     CDS             3724..6822
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CPSase_L_D2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_22"
                     /sec_met_domain="CPSase_L_D2 (E-value: 5.3e-84, bitscore:
                     271.8, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LKEEGVEVVLVNSNPATIMTDKDIADQVYIEPLTVSVLEKIIAKE
                     KPDSVLPTLGGQAGLNLGMELEEKGILEKYNVRLIGTTAETIFKAEDRQAFKDTMEKIG
                     EPCAASQVVHNVEDGIKFTNTIGYPVVLRPAYTLGGSGGGIAHNETELVEILTNGLRLS
                     RVGEVLVERCIAGWKEIEYEVMRDANGNCITVCNMENIDPVGVHTGDSIVVAPSQTLGD
                     KEYQMLRTSALNIISELNITGGCNVQYALNPDSFEYCVIEVNPRVSRSSALASKATGYP
                     IAKVAAKIALGYTLDEIKNAITGKTYASFEPMLDYCVVKIPRLPFDKFITAKRTLTTQM
                     KATGEVMSICNNFEGALMKAIRSLEQHVDSLMSYDFTGLSDKELDEQLHVVDDRRIWVI
                     AEALRRGVSYDKIHEITKIDRWFIDKLAILVEMENQLKNEPLTVELLKEAKRIEFPDSV
                     IAKLTGKTEKEIHDMRYENGIVAAFKMVDTCAAEFEASTPYYYSVFGSENEAIETNPKK
                     KVLVLGSGPIRIGQGIEFDYCSVHCTWAFAKEGWETVIINNNPETVSTDFDIADKLYFE
                     PLTPEDVESIVKLEKPDGAVVQFGGQTAIKLTESLMKMGVKILGTKAEDVDAAEDRELF
                     DEILEKTQIPRAAGGTVFTAEEAKEVANRLGYPVLVRPSYVLGGQGMKIAFNDDEIEEF
                     IGIINRIAQDHPILVDKYLQGKEIEVDAVCDGTDILIPGIMEHIERTGVHSGDSISVYP
                     APTISDHVKETIVEYTKRLAQALHVIGLINIQFIAMDEQVYVIEVNPRSSRTVPYISKV
                     TGIPIVDLATKVIIGDTIRGLGYEPGLAPTADYIAIKMPVFSFEKLRGAEISLGPEMKS
                     TGECLGIAKTFNEALYKAFLGAGVTLPKYKQMIMTVKDADKPEAVGVAKRFEALGYKIY
                     ATRSTAKYLQEHGVNALRVNKISQESPNVMDLILGHKIDLVIDTPTQGNGDKTRDGFLI
                     RRNAIETGVYCITAMDTANALARSLETATDDLTPVDIATVKNL"
     CDS             complement(7013..8308)
                     /locus_tag="ctg20_23"
                     /transl_table=11
                     /translation="MQFVKTADLKPGMRLAKPIYNKMGVLLYERDTLLTMQGINSIENF
                     GLIGIFILEPAEPVPPLSREDLEFEQFQTIYVFKLKENMDRLQANQAPVSLSDLVRDIQ
                     THYGSLDHKLNFAQNLRSSADFVYKHSISVGILCAMITNQMHLPAAEQTALITAALLYD
                     FGYLYVPQTVLDKGDDLTTADKDFIQLNLERGYETLRPDRGDYKFPVHTLDIIQQIIFK
                     NSRTLKVKEPADNIRLLVDILAVADEFDHLTAMNINKPPISEIAAMGRLKKDKATYNPL
                     VLSALAECIHILPTGACVDLSDGEKALVLAENPADFLHPMVLKFSTNMIYDLSDPVINK
                     SLKITDIMKTMDNRIALDKDSVKHFVSDAYIKETADRFRKVKLQIAQHNQSKLEQKAAS
                     ALMSSASVIPQDALGTEKPLAQKKPRKKMKLR"
     CDS             8519..9673
                     /locus_tag="ctg20_24"
                     /transl_table=11
                     /translation="MRHNFLRRILGGILTGCILVTATVHAGTTQKDIDQAKDQITDLKK
                     QKEDAKDQVDSLTNEKQGLESDLSGLNGQLNTITSDMNQLEQQAAQKEDEINTAAEDLK
                     RSEERSAEQYEDMKVRIQYIYENGNQSVWDMLIHVSSIAEFLNQAEYTSAINQYDRNML
                     TAYQELTEQIKKQKKELEEQKEELTVLQQEKQKEQEKVNSLIEDTQKKIQESSEKIEDA
                     QSDVESIDAKIEKMIEYEKQLEIQKAKEDAARLAAIKKQEQENRSNVTYAPAQSDAYLL
                     AAIIQCEAWGEPYDGKLAVGSVIMNRVRSSYFPNTVSGVIYQGGQFSPVASGRLAYRLE
                     QGVASDCMSAAQAVLGGTSTTNCLYFRVNNGIIEGTVIGNHVFY"
     CDS             9774..10004
                     /locus_tag="ctg20_25"
                     /transl_table=11
                     /translation="LQLIVKYVSIRKYKKCRKIADYIANKLFKMKEKKINFNRKFEFIF
                     LKKIVKKLTAFFGNFKEKETNSLQKQSFVLN"
     CDS             10001..11200
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: Thiolase_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: Thiolase_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_26"
                     /sec_met_domain="Thiolase_N (E-value: 1.3e-97, bitscore:
                     317.0, seeds: 30, tool: rule-based-clusters)"
                     /sec_met_domain="Thiolase_C (E-value: 4.1e-51, bitscore:
                     162.7, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LKGEFKMAKKVVLAGACRTAIGKMGGALSNTPAADLGAIVIKEAL
                     RRANVKPEMVDEVKMGCVIQAAQGQNVARQAAIKAGLPIEVPAITINVVCGSGLKCVND
                     AATMIMAGEADIVVAGGMENMSMAPYAMTKARFGYRMNNATIIDTMVNDALTDAFNHYH
                     MMITAENVCDKYGITREELDEFSANSQQKCEKAIAEGKFDDEIVPVPVKVKKEIVDFVK
                     DEGPRAGTTAESLAKLKCCSGKEGGLVTAGNASGINDGAAAIVVMSEEKAKELGVTPMA
                     TWVAGALGGVEPEIMGVGPVASTRKVLAKTGLSIDDMDLIEANEAFAAQSIAVARDLKF
                     DMSKVNVNGGAIALGHPVGASGCRILVTLLHEMQKRDAKRGLATLCIGGGMGCSTIVER
                     "
     CDS             11294..12166
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: HCDH_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: HCDH"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_27"
                     /sec_met_domain="HCDH (E-value: 4.7e-35, bitscore: 111.1,
                     seeds: 68, tool: rule-based-clusters)"
                     /sec_met_domain="HCDH_N (E-value: 3.4e-63, bitscore: 203.6,
                     seeds: 60, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVGVIGAGTMGQGIAKAFAQVEGYEVALCDIKQEWAEGGKEKIK
                     KGYARLVEKGKMTQEAVDGILAKITPGLKEDLCKDCDLIVEAAFENMEVKKTTFKELDE
                     IAKPDCIFASNTSSLSITEIGNGLNRPMVGMHFFNPADRMKLIEVIAGVNTPDETVSAI
                     KKISEEIGKTPVQVNEAAGFVVNRILIPMINEAAFIKMEGVSDIAGIDAAMKLGANHPM
                     GPLELGDFIGLDICLAIMDVLYKETGDSKYRACPLIRKMVRGGNLGAKSGKGFYVYNAD
                     RTKTPVDAQ"
     CDS             12196..12774
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_28"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 1.3e-20, bitscore:
                     64.4, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 2.2e-40, bitscore:
                     128.8, seeds: 796, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDFTLDKKHEMARSLFKEFAETEVKPLAQETDETEAFPAETVKKM
                     QKYGFMGIPVPKEYGGQGCDPLTYVMCVEELSKVCATTGVVVSAHTSLCIDPIMTYGTE
                     EQKQKYVKPLATGEKLGAFALTEPGAGTDAQGAQTKAVLDGDEWVLNGSKCFITNGKVA
                     DVYIVIAITSITEDKRGRKKKNFSAFIVDK"
ORIGIN
        1 agctgatcgc acttgcaaaa gagaaaaatg ttaactttat gttcgaagca agcgtcggtg
       61 gcggtatccc gatcatccgt ccgttaaatt cctgtctgac tgctgatgag attgaggaaa
      121 tcacaggaat cgtcaatgga acaacgaact atatgatgac tgaaatgtca gaaaaaggtg
      181 ctgattttga tgaggtatta aaagatgcac aggcaaaagg atatgcggag aaagatccga
      241 cagccgatat tgaagggtat gatgcctgca gaaagattgc aattctgaca tcacttgtct
      301 gtggacagca ggtagatttt gaggatatcc acacagaagg aattacacat atctctgcga
      361 ccgatattaa atatgcaaaa gccatgggaa gagccattaa acttcttgca acaagcaaaa
      421 agacagacgg cgggtatgtt gcaatggttg ccccattctt attaccgaaa gagcatccgt
      481 tatataatgt aaacggtgtg ttcaatgcaa tctttgtccg tggaaatgta cttggagatg
      541 caatgttcta tggaagcggt gcaggaaaac tcccgacagc cagtgcagtt gttgcggatg
      601 ttgtggaaat ggcaaagaat cttgataaga atataccggt ggagtggagt tcaaagaaat
      661 tagaactggt agattaccgc agcgcagaga accgtttctt tgtcagagtg tcaggtacag
      721 ataaggcatc tgtggaaaaa atatttggaa atgtagacta tattgatgcg cagggtgtta
      781 caggagaact tggctttgta acagaagaga tgacagaaga ggctttagag aacaaaaaag
      841 cagcatatgg ggaagtgttg aatgtcattc gtgtagcgta aaaagaaaag caggtcgtga
      901 atcacatgga aggcggttca cgggtctgct ttttttatga aaacggaaga gtgtgaaaag
      961 taagattgtt tgcacataga tttgtgctta cacacgaatt tgagatacgc aaaagcagcg
     1021 tggaaatgga gaggaatatg acgttaaatg aatgttacga agaaatgggc gcggatctgc
     1081 acgaagtgct gcggcggctc aagacggagg agaggatcgg gaaattttta aaactgattc
     1141 tgacggatac gaattatgag tcgctgtgta aggcgctgga agaaaagaat tatgagcagg
     1201 cgtttacaca tatacataat ttaaaggggc tggcaatgaa tctgggactg acaccgcttt
     1261 tggttccggc gcaggagttg tgtgaggaac ttagggatgg cgaaccggaa agggagctta
     1321 aaccgctttt ggatgaggtg gcggcggctt atcagaaagt ccttggtatt gtcgaaagac
     1381 ttgactgaga taacagtgtg aaaagctgga attttggctg attctttgta atgagttatt
     1441 cggaaatgga gaacagtatc aaaggtaaag atgcattttt gaatctctga catatgataa
     1501 aacagaaggt tttatgtctg aggtagaaaa aagtgcaggt aattcttttg atcatagcag
     1561 tcagtgtgga tgtctttgtg gcatgtgtgg cgtgtgggag tgagcagata aagatcggat
     1621 ctgcggcagc gttatgcatc agcacggtct gcagtggaat attagggata tcactttatg
     1681 cggggatggc gttacagggg gtacttttaa aaaaatatgc attatactta agttttttcg
     1741 gactgcttgc agtgggaatt tttaagctga cagagtatgc gatcagaaaa tatattgagc
     1801 gtcataagtt cctctgcaag aaagtcaaaa tctctttttc acagctcagt tttattctga
     1861 gtatctacaa caatccggta atggcagacc gcgatcactc ggcgacgatg tcgtgtttgg
     1921 aggctgtatt ttttgcactt gcaatgtcat tggacgggat gtttggagga cttggtgcag
     1981 gatttaccgg aaagaatatt tttcttacgg tgcttggaag ttttgtcgtc agtttctgtg
     2041 cagtactttg cggatgcagg attggcatgc aggcatctaa gcggtggaaa gccgatgtat
     2101 cgtggcttgg aggcgtgttg tttgtaatcc ttgcgtttca gaagattatt taaaaagtca
     2161 gttccatgct gcccattgct gcaggaaaat cagaaaagtc tgttactgtt tatgccttgc
     2221 cgggcgtttg ggtaataaag attttctgcg tatgggcggc acatactgcc gctttctatg
     2281 gatttggaaa taatgtataa atatacataa atatgcataa aatcttagtg ctatttgttt
     2341 tgggaaaaag gttgaaaaat atcttatgat atgatacact ttttacaatt taggaaaaag
     2401 actataggta ctaataaggg aaagttcagt caggggactg tctggatgga aaaagaagaa
     2461 aaacggcgac gttttttttt ttggaaaaaa agtgaaagga cagggaaacg aatgaaagct
     2521 catttaatac tcgaagatgg gaatgtattt accggaacaa gtataggttc tactagggaa
     2581 gtcatcagtg aaatcgtatt taatacgtcg atgacaggtt atctggaggt tctgactgac
     2641 ccgtcgtatg cgggacaggc ggttgttatg acttatccgc tgattggaaa ttatggaatc
     2701 acaccggata tggagtcagg cagaccgtgg ccggatggat atatcgtaag ggagttatca
     2761 agaatgccga gtaacttccg tgaggaggga acgattcagg atttcctcac gaaatatgac
     2821 attccgggta tagcagggat cgacacccgt gcactgacca agatccttcg tgagaaggga
     2881 accatgaatg gtatgatcac cacgaataat aactataata tagaagaaat tattcccaga
     2941 ttaaaagcat acacgacagg taatgttgtg gacaaagtta cctgcagtga aaaacgagta
     3001 ttaaaaggaa atggcaagcg agttgctttg cttgaccttg gagcaaaaaa taatattgcc
     3061 cagtctttaa ataaacgtgg ctgtgaagtg acgatctatc cggcacatac gactgcggaa
     3121 gagatccttg caacaaatcc ggatggaatc atgttaagca acggacctgg agatccgaag
     3181 gagtgcaagg agattattgc tgagatcaaa aaattatatg actccgatac accaatcttt
     3241 gcaatctgct taggacatca gctgatggca cttgcaaccg gcgctgacac acataagatg
     3301 aaatacggac accgtggcgg caaccatccg gtaaaagatt tagaaaccgg aagagtatat
     3361 atttcctccc agaatcacgg ttatgtggta gatacggata cacttgatcc aaagatcgcg
     3421 aaaccggcat ttgtgaatgt aaacgatgga acgaatgagg gactttccta tgtaggcaaa
     3481 aacattttta ccgtacagtt ccatccggaa gcatgtccgg gaccgcagga ttctgcatac
     3541 ctgtttgatc gttttatatc aatgatgtaa aaaaatctta cgttattgtc taacaaattt
     3601 taggaggaag aattaatgcc aagaaatcat gacataaaaa aagttttagt aattggttcc
     3661 ggcccgatcg taattggaca ggctgcagag tttgactatg caggtacaca ggcatgccgc
     3721 tcattgaaag aagagggtgt tgaggttgtg ctggtaaact caaacccggc gacgatcatg
     3781 acagataaag atatcgcaga tcaggtttat attgagccgc ttacggtatc tgttttagag
     3841 aagatcattg caaaagaaaa accggacagc gtattgccaa ctttaggtgg acaggcaggc
     3901 ttaaaccttg gtatggagtt agaggaaaaa ggcatccttg aaaaatataa tgtcagactg
     3961 atcggtacaa ctgcagagac gatttttaag gctgaggatc gtcaggcatt caaagatacc
     4021 atggaaaaga tcggtgagcc ttgtgcagca tcccaggtcg tacacaacgt agaggatggt
     4081 atcaagttta ccaataccat tggttatccg gtcgtacttc gtccggcata tacgcttggc
     4141 ggaagcggcg gtggtatcgc acataacgag accgagctgg ttgagatctt aacaaacggt
     4201 ctgcgtcttt cccgtgttgg agaggtattg gtagagcgtt gtatcgcagg atggaaagag
     4261 atcgagtatg aggtaatgcg tgatgcgaac ggcaactgta tcaccgtatg taacatggaa
     4321 aatatcgatc cggtcggtgt acataccggt gattccatcg ttgttgcacc ttcccagaca
     4381 cttggcgata aggaatacca gatgcttcgt acatctgcat taaatattat ttccgagtta
     4441 aatatcaccg gaggatgtaa cgtacagtat gcattgaatc cggacagctt tgagtactgc
     4501 gttatcgagg ttaacccgcg tgtatcccgt tcttctgcac ttgcatccaa agcaaccgga
     4561 tacccgatcg caaaagttgc tgcaaagatc gcattaggtt acaccttaga tgagatcaaa
     4621 aatgcaatta ccggaaaaac ttatgcaagt ttcgagccga tgcttgacta ttgtgttgta
     4681 aagattccga gacttccatt tgataaattc atcacggcaa agagaaccct gaccacacag
     4741 atgaaggcaa ccggagaggt tatgagtatc tgcaataact ttgagggtgc attgatgaaa
     4801 gcaatccgtt ccttagagca gcatgtggac agtttaatgt cttacgactt taccggactt
     4861 tccgataaag agttagatga gcagctgcat gtagtggatg accgccgtat ctgggtgatc
     4921 gcagaggcac tgcgcagagg cgtaagctat gacaagatcc atgagatcac gaagatcgac
     4981 cgctggttta tcgacaaact tgccatcctg gttgagatgg aaaaccagtt aaagaatgag
     5041 cctttgactg tagaattatt aaaagaagca aaacgcatcg agttcccgga cagcgttatt
     5101 gcaaaactga ccggaaagac cgaaaaagag atccatgata tgcgttatga aaatggtatc
     5161 gtggcagcat tcaagatggt agatacctgt gccgcagagt ttgaggcatc cacaccgtac
     5221 tactattccg tattcggaag cgagaacgaa gccatcgaaa ccaatccaaa gaaaaaggta
     5281 ctggtacttg gttctggtcc gatccgtatc ggacagggta tcgagtttga ttactgctcc
     5341 gtacactgta cctgggcatt tgcaaaagag ggatgggaga ccgtcatcat caacaacaac
     5401 ccggagaccg tttccactga ctttgatatc gcagacaaac tttattttga acctttaaca
     5461 ccggaagatg tagagagcat cgtaaaactg gaaaaaccgg atggtgctgt cgtacagttt
     5521 ggtggacaga ccgcgatcaa gttaaccgag agcctgatga agatgggtgt taagatcctt
     5581 ggaacaaaag cagaggatgt cgatgcggca gaggaccgtg agcttttcga tgagattctg
     5641 gaaaaaacac agattccgag agctgcaggt ggaactgtat ttaccgcaga ggaggcaaaa
     5701 gaagttgcaa accgtctcgg ctatccggta ctggtaagac cttcctatgt actcggtgga
     5761 cagggtatga agatcgcatt caacgatgat gagatcgagg aatttatcgg tatcatcaat
     5821 cgtatcgcac aggatcaccc gattctcgta gataaatatt tacagggaaa agaaatcgag
     5881 gtcgatgctg tatgtgacgg gaccgatatc ttaattcctg gtatcatgga gcatatcgaa
     5941 cgtaccggtg tacactccgg agacagtatt tccgtatacc cggcaccgac gatcagtgac
     6001 catgtaaaag agacaatcgt tgagtatacg aaacgtctgg cgcaggcact gcatgtcatc
     6061 ggactgatca atatccagtt catcgctatg gacgagcagg tatatgtcat tgaggtaaac
     6121 ccgcgttctt cgagaaccgt gccatacatc agcaaagtaa ccggtattcc gatcgttgac
     6181 cttgcaacga aagtaattat cggtgatact atccgcggac ttggatatga gccgggactt
     6241 gcaccgaccg cagattacat tgcaatcaag atgccggtat tctccttcga gaaactgcgt
     6301 ggcgctgaga tctccttagg accggagatg aaatcaaccg gtgagtgcct tggtattgca
     6361 aagaccttca acgaggctct ctacaaagca ttcctcggcg caggtgtgac tttaccgaaa
     6421 tacaaacaga tgatcatgac cgtcaaagat gcagataagc cggaagcagt cggcgttgca
     6481 aaacgttttg aggcacttgg ctacaagatt tacgcaacca gaagtaccgc aaaatattta
     6541 caggagcacg gcgtcaatgc acttcgtgtc aacaagatct cccaggagtc accgaacgtt
     6601 atggacttaa tcttaggaca taagatcgac cttgtcatcg acacaccgac acagggaaat
     6661 ggtgataaga ccagagacgg attcctgatc cggagaaatg caatcgagac aggtgtttac
     6721 tgtatcacag caatggatac ggcaaatgcg ttggcacgca gcttagagac tgcgaccgat
     6781 gatctgacac cggtggatat tgcgaccgta aagaacttgt agttctttga atcttataat
     6841 atagcaaaaa cagcacaaat ccaaaaggag gcgtgctgtt tttgcttttg cggaatatgg
     6901 atattggcga caacatgaaa aaacgacatg aaagcagtta agaaattgct ttcatgtcgt
     6961 tttttatatc gccggaatat ccactccaac atatagaaaa aagtcgcgcg gattaacgga
     7021 gtttcatttt tttgcgcggt ttcttttggg ccagtggttt ttctgtgccc aaagcatcct
     7081 gcgggatcac agatgcacta ctcattaagg cgcttgccgc tttttgttcc agtttacttt
     7141 gattgtgctg tgcaatctga agcttgacct tgcggaaacg gtctgccgtt tctttgatgt
     7201 aggcatcgga aacaaaatgc tttacagaat ctttatccaa tgcgatacgg ttgtccatgg
     7261 ttttcatgat atctgtgatc tttaaagatt tgttgatcac cgggtcactt aaatcgtata
     7321 tcatgtttgt ggaaaacttc agtaccatcg gatgaagaaa atcagccgga ttctctgcaa
     7381 gcacaagggc tttttcgcca tcggaaagat ctacacatgc accggtcgga agaatatgga
     7441 tacattctgc taaagcggaa agtacgagcg gattgtaggt ggctttatcc tttttcagac
     7501 gtcccatggc agcaatttct gaaattggcg gtttgttaat gttcattgcg gtcagatggt
     7561 caaattcgtc cgctactgct aaaatatcga cgagaagacg gatattgtct gccggttctt
     7621 tgacttttaa agtacggctg tttttaaaaa tgatctgctg gataatatca agcgtatgta
     7681 ccggaaattt ataatcacca cggtccggac ggagtgtttc ataaccgcgc tctaagttga
     7741 gctggataaa atccttatct gctgttgtaa ggtcatcccc tttgtctaac actgtctgtg
     7801 gtacatacag ataaccaaaa tcgtagagaa gcgcagctgt gataagggct gtctgttctg
     7861 cagcaggcag atgcatctga tttgtgatca tcgcacagag aatgccgaca ctgatggaat
     7921 gtttgtaaac aaaatctgca gaacttcgca ggttttgtgc aaaatttaat ttgtgatcaa
     7981 gactgccgta atgtgtctgg atgtctctga cgagatcgct cagcgaaaca ggtgcctgat
     8041 tggcctgcag acgatccata ttttctttta atttaaaaac atatatagtc tggaactgtt
     8101 cgaattcaag atcctctctg gaaagaggcg gtaccggctc tgccggctca agaataaaaa
     8161 taccgatcag accaaagttt tcgatactgt taataccctg catggttaaa agtgtgtctc
     8221 tttcataaag aagaacaccc atcttattgt agattggttt tgcaagtctc atgccgggtt
     8281 ttaaatctgc tgtttttaca aattgcatag gtaaatcctc cccctgtgat gattatcagg
     8341 ctctttttat accatatcca gacatcagat gcctgaatat tcccccaata atggtatgtg
     8401 aaaaaattaa tattcatatt gtgctttaca tgctataata ccatattaat agaagaaata
     8461 caatgaacga aaaatacaac agtagcagaa agcttactgt tcagccgaaa ggaacagcat
     8521 gagacacaat tttttgagaa gaatcctggg aggaatactg accggctgca tacttgttac
     8581 ggcaactgtc catgcaggaa cgacacagaa agatattgat caggcaaaag accagatcac
     8641 agaccttaag aaacagaaag aagatgcgaa agatcaggtg gacagcctga ccaatgaaaa
     8701 acagggattg gagagcgacc ttagcggact gaacggacag ttaaatacga tcacttccga
     8761 tatgaaccag ttagagcagc aggcagcgca gaaagaggac gagatcaata cggcggcgga
     8821 agatctgaaa cgttccgagg aacgatctgc agaacagtat gaagatatga aagtgcgcat
     8881 tcagtatatt tatgaaaatg gcaatcagtc tgtatgggac atgcttattc atgtgtcctc
     8941 cattgcagaa tttttaaatc aggcggaata tacaagtgca atcaatcagt atgacagaaa
     9001 tatgcttacg gcatatcagg agctcacgga gcagatcaaa aaacagaaaa aggaactcga
     9061 ggagcagaag gaagaactga ctgtattaca gcaggaaaaa cagaaagagc aggaaaaagt
     9121 caacagcctg atcgaggata cgcagaagaa gatacaggaa tccagcgaga aaattgaaga
     9181 tgcacagtcc gatgtggaat cgatcgatgc aaagatcgag aaaatgatcg aatacgaaaa
     9241 gcagcttgag atacagaagg caaaagagga tgctgcgcgc cttgcagcca tcaaaaagca
     9301 ggaacaggaa aacaggtcga atgtgacata cgcaccggca cagagcgatg cgtatctgtt
     9361 agctgccatc atccagtgtg aggcatgggg cgagccatat gatggaaaac ttgcggtggg
     9421 cagcgtgatc atgaaccgtg tcagaagctc ctattttccg aatacggttt ccggtgtgat
     9481 ttatcaggga gggcagttct ctccggttgc cagcggtcgt cttgcatacc gtctggagca
     9541 gggagtcgct tccgattgta tgagtgcggc acaggcggtt ctgggtggaa cgagcacaac
     9601 aaattgtctg tattttcgtg tgaataacgg cattatagaa ggaacagtta taggtaatca
     9661 tgtgttttat taaacaaaat gataaaatga taaaaattta acaaaaaacc ccgcaaaatg
     9721 gagcaaaaag gaagtaaaaa attgtttaca aagatgaaaa ataaagaaag ctattgcaat
     9781 taattgtgaa atatgttagc ataagaaagt acaagaaatg cagaaaaata gctgattaca
     9841 tagcaaataa gctttttaaa atgaaagaaa aaaagataaa tttcaaccga aagtttgaat
     9901 ttattttttt aaaaaagatt gttaaaaaat taacagcatt tttcggcaac tttaaagaga
     9961 aagaaacaaa ttctctgcaa aagcagagct ttgtgttaaa ttgaaaggag aattcaaaat
    10021 ggcaaagaaa gtagttttag caggtgcctg ccgtaccgca atcggtaaaa tgggtggagc
    10081 attaagcaat actccagcag cagacttagg tgcaatcgtt atcaaagagg ctttaagaag
    10141 agcaaacgtt aaaccagaga tggttgacga ggtaaaaatg ggttgtgtaa tccaggcagc
    10201 tcagggacag aacgttgcac gtcaggcagc aatcaaagca ggactgccaa tcgaagttcc
    10261 ggcaatcaca atcaacgttg tttgtggttc tggtttaaaa tgtgtcaatg atgcagctac
    10321 catgatcatg gcaggtgaag ctgatatcgt tgttgcaggt ggtatggaaa acatgtctat
    10381 ggcaccatat gctatgacaa aagctcgttt tggatatcgt atgaacaatg caacgatcat
    10441 cgatacaatg gtaaatgatg cattaacaga tgcattcaac cactatcata tgatgatcac
    10501 agcagagaac gtatgtgata aatatggcat tacaagagaa gaacttgacg agttctcagc
    10561 aaacagccag cagaaatgtg aaaaagcaat cgctgaaggc aaatttgatg atgagatcgt
    10621 tccggttcct gttaaagtga aaaaagagat cgttgatttc gtgaaagatg agggaccacg
    10681 tgccggtaca actgctgagt ctttagcaaa attaaaatgc tgctccggta aagagggcgg
    10741 acttgttaca gcaggtaacg cttccggtat caacgatggt gcagcagcaa tcgttgttat
    10801 gagtgaagaa aaagcaaaag agcttggtgt tacaccaatg gctacatggg tagcaggtgc
    10861 tcttggtgga gttgagcctg aaatcatggg tgttggtcct gttgcttcta caagaaaagt
    10921 attagctaaa acaggtttat ccattgatga tatggactta atcgaagcaa acgaagcatt
    10981 cgcagctcag tctattgcag tagcaagaga tctgaaattc gatatgtcaa aagtaaacgt
    11041 aaacggtggt gcaatcgcat taggacaccc ggtaggtgct tccggatgcc gtatccttgt
    11101 tacattactg catgagatgc agaagagaga cgctaagaga ggtcttgcta cactttgcat
    11161 cggcggtggt atgggatgct ctacaatcgt tgagagataa tagtttttta tagtaattcc
    11221 cggggaatga cttcccgggg attgcatttt tcaaacatac agttaacata attattttca
    11281 ggaggtaacc gaaatgaagg ttggcgttat tggtgcagga actatgggac agggcattgc
    11341 aaaagcattt gctcaggtag aaggatatga agtagcactt tgcgatatca agcaggagtg
    11401 ggctgaaggc ggaaaagaga agatcaaaaa aggttatgca agattagtag aaaaaggaaa
    11461 aatgacacag gaagctgttg atggcatcct tgcaaaaatc actccaggtt taaaagaaga
    11521 cctttgcaaa gactgtgatc tgatcgtaga ggcagctttc gagaatatgg aagtaaagaa
    11581 aactactttc aaagaattag acgagatcgc aaaaccagat tgtatcttcg cttccaacac
    11641 atccagtctt tctattacag agattggaaa cggattaaac cgtccaatgg ttggtatgca
    11701 tttcttcaac ccggcagacc gtatgaaact gatcgaggtt atcgctggtg tgaatactcc
    11761 ggatgaaact gtttccgcta ttaagaaaat ttctgaagag atcggaaaaa ctccggtaca
    11821 ggttaatgag gctgctggtt tcgttgtaaa ccgtatctta atcccaatga tcaacgaagc
    11881 tgcattcatc aaaatggaag gtgtttccga tatcgctggt atcgatgcag ctatgaaact
    11941 tggtgctaac cacccaatgg gaccgttaga gttaggtgat ttcatcggtc ttgatatctg
    12001 ccttgctatc atggatgtac tttacaaaga gacaggcgac agcaaatatc gtgcatgccc
    12061 actgatccgt aagatggttc gtggtggtaa ccttggagca aagagcggca agggattcta
    12121 tgtatacaat gctgatcgta caaagactcc ggtcgatgct cagtaaaata aatatttatg
    12181 gaggaaaatt agatcatgga tttcacttta gacaagaaac atgaaatggc gcgttcctta
    12241 ttcaaggaat ttgctgaaac agaagtaaaa ccgcttgcac aggaaacaga tgagacagaa
    12301 gctttcccgg ctgaaacggt taagaaaatg cagaaatacg gattcatggg aatcccggtt
    12361 ccgaaagaat acggcggaca gggttgtgat cctcttacat acgttatgtg cgtagaagag
    12421 ttatctaaag tttgcgcaac cacaggtgtt gttgtatctg cacatacatc tctctgcatc
    12481 gatccgatca tgacatacgg tacagaagag cagaaacaga aatatgtaaa accacttgca
    12541 acaggcgaga agttaggtgc attcgcatta actgagccgg gtgctggtac tgatgcacag
    12601 ggtgcacaga caaaagctgt tttagacggt gacgaatggg tattaaacgg atctaaatgt
    12661 ttcattacca acggtaaagt tgcagacgtt tatatcgtaa tcgcaatcac aagcatcaca
    12721 gaggataaga gaggcagaaa gaagaaaaac ttctctgcat tcatcgttga taaggg
//
