LOCUS       c00027_gnlPro..        16770 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BMGDPBIK_27.
ACCESSION   c00027_gnlPro..
VERSION     c00027_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 23:59:15
            Original ID  :: gnl|Prokka|BMGDPBIK_27
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 11481
            Orig. end    :: 28251
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16770
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[21481:24476]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12995
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..16770
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16770
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             963..2528
                     /locus_tag="ctg27_7"
                     /transl_table=11
                     /translation="MRKQSKIIFYAGIVLGVAAVLTGVALSGGEKIPKDFTVSYDGIKT
                     ADITAGVSVHDPSVIEADGTYYIFGSHMSGASSEDLRNWTSIGDGYTQSNPIFDDLLGT
                     EHVFDYTGSRDSVIPTDDGTYHVWAPDVVYNRAQDLYYMYFCTSSTWNASNLCYAVSDK
                     PEGPYTWKGALIYSGFAKDTIGATDVLDYVDISYAKKNYIIAGNKYNYEKYPNAIDPTV
                     FYDADGKMWMVYGSXXXSWWVVIFLLEIDEKTGLVIHPKEDEKNGVDPYFGKRLLGGGH
                     KSIEGPYILYDEESGYYYLFVSYGSLTREGGYQMRVFRSKTVDGEYVDMNGAYPGMWDD
                     NAAYGLKLSGNYYLPGLNKAYMATGHNSAFVDEDGKKYIVYHTRFDNGQEYHEPRVHQY
                     FLNQDGWPCMLPYATDGETIAESGYDISEVEGTYYVINQGTAISARIAQPVKLVLMDNG
                     NVYGENLDGTWSMEEGTCYMTLTYGGKEYNGVFCQMKDEAGTDVMTFSAAGADESVWGV
                     KYFE"
     CDS             2641..4026
                     /locus_tag="ctg27_8"
                     /transl_table=11
                     /translation="MLKAIDDFVWGVPLIVLILAVGIFLTIRLRGLQITKLPLAIKHMV
                     ANEKNGEHGEVSSFGALCTALSATIGTGNIVGVATALVAGGPGALFWMWIAALLGTATK
                     YSECLLAIKYRVVAKDGHIVGGPFYYIENGMGEKWKWLAKIFAFFGVGVGLLGIGTFTQ
                     INGITSAVNNFFDPQNTWTVELFGRTYSWTVVIAGIILTLCVALVIIGGIKRISTVAQV
                     VVPFMALLYVVVVLIILFTHLSAIPGAIVEIVQSAFGLRAAAGGTLGSILIAMQMGIAR
                     GIFSNEAGLGSAPIAAAAAKTNEPVTQGLVSMLGTIIDTVIICTMTGLSIVITGAWDMG
                     LEGVSVTTKAFQIGLPFPEQVASFVLMLCLVFFAFTTILGWNYYSEKCLEYLVGDKKTV
                     LKGYRWLYILAVFIGPFMTVSAVWTIADIFNGLMALPNLVALVALSGVVVAETKKYFEK
                     QKY"
     CDS             4211..5173
                     /locus_tag="ctg27_9"
                     /transl_table=11
                     /translation="MSDEKSLKYNEPWILQRADPYVYRHTDGSYYFTASVPAYDGIVLR
                     RAGTLAELSGAEEVMVWKKHESGPMSYHIWAPEIHYLFGKWYIYFAGGEAEDIWKIRPY
                     VLECSGDDPLTDEWVELGKMKRAAEDEFSFEAFSLDATVFENKGEYYYVWAEKVGVGKM
                     ISNLYIANMESGNQLKTVQILLTTPDYDWERKGFWVNEGPAVIHHDGKLFLTYSASETG
                     VDYCVGMLSIDEDADILDPRLWKKERYPVLKTCEKLGIYGPGHNSFTVDEDGNDVMVYH
                     ARTEAEINGDPLYNPNRHAMLMKVKWDEAGRPVFSYENK"
     CDS             5190..6695
                     /locus_tag="ctg27_10"
                     /transl_table=11
                     /translation="MAKLIINEENKKSRIEPEIYGHFSEHLGRCIYEGIYVGEKSEIPN
                     VNGMRTDVVDALKELKVPVLRWPGGCFADEYHWMDGIGPKEKRKKMINTHWGGVVEDNS
                     FGTHEYMELCRQIGCKTYVNGNLGSGTVREMSEWVEYMTFEGVSPMADLRKENGHEAPW
                     KVDYFGVGNENWGCGGNMTPEYYANEYRRYQTYVRNYHPDRPIKKICCGANVADYYWTK
                     GVLNTAFDHAEQWHGFMDGLSLHYYVHPEGWEIKGSSTDFDADVWYKTLSKALYMETLI
                     ERHGAIMDEYDPDKKVGMIVDEWGTWYTCEPGTNPGFLYQQNTVRDALVAGITLNIFNK
                     HSDRVKMAALAQMVNVLQSVLLTEGGQMIKTPTYHVMHMYRHHQGADLLESTLTGAGEI
                     GPDEWKVPKITESVSMDKDGVITVTMNNLSVEASEKVEIQLANRGYHVTEAKIVTDSDM
                     HAHNTFEAPDTVTEKDFTAYEETENGVNVTMPANSVIELRLAK"
     CDS             6785..7027
                     /locus_tag="ctg27_11"
                     /transl_table=11
                     /translation="MAQICKKCLLREMAEADAKMIEKYKEAIKKEDQVSESEYERRLTV
                     CKTCELLNAGTCGACGCYVELRAAAAVSKCPYKKW"
     CDS             complement(7068..7994)
                     /locus_tag="ctg27_12"
                     /transl_table=11
                     /translation="LLHITSLNEGLELFKALGSDVRIEILNILLENDNMSMNELASRLN
                     ITNGALTSHIKKLENCGLITTSSESAVHGNQKICSIHLDKILIDLEKPAEIENVYHTEL
                     KVGHYTNYQICPTCGLASADALIGEVDDPRYFEHPDRYNADILWFTRGYVEYAIPNFIP
                     ASKKITQITISAELSSEAPGTNNDWPSDISFYLNDIHIGDWTSPGDFGDVKGLLTPDWW
                     YANWNQYGLLKQLVINQKGTYIDGLKISDVKIDDFHLNCHSSIRFRLAVEDDARHVGGL
                     TIFGKSFGNYSQDIKVSLGYAPVEEMK"
     CDS             complement(8026..8472)
                     /locus_tag="ctg27_13"
                     /transl_table=11
                     /translation="MKIGIISDTHGIFREEWHRYLDSCDYLIHAGDFCTQKNYDCFRNF
                     GIPLYMVRGNNDRGDWAKNLPEFLQFRIGGKTFFLVHNQFDLPFDLTDADFLIFGHTHH
                     YTFYERFNKVYINPGSASDGRGDSKSLAILTVSGNDYSLERVIL"
     CDS             8678..9610
                     /locus_tag="ctg27_14"
                     /transl_table=11
                     /translation="MENSVLEEKVFHKVMKNVPFGLVVSSEGRKRKVYYVNTMAYHMLG
                     YTREEFIEKVQDGWSRFVDIDLRTVMREHHEEILTGESFELTAQTETKDGNKKWLSFRV
                     MVSMDVISSQLKPVSYITITDVTEKVEKNRRYAREREYLRDCAARDSMTRLLNRGTMED
                     RIKEELESVAEGQNYAYIAIDLDNFKQVNDVYGHWVGDRVIMSMSNILREVYGNQVSIG
                     RMGGDEFAVFLPDVKDRMWIQGQADEVLYRLRRQKEMIGMAEEPTASIGIAFGPEDGTS
                     FRELYHRADAALYQVKKEEKNSIAIYTMI"
     CDS             10001..12229
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg27_15"
                     /sec_met_domain="Gly_radical (E-value: 3e-46, bitscore:
                     147.0, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 2.9e-281, bitscore:
                     924.6, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQNEWRDFNGGAWENEVNVRDFIQRNYKPYDGDSSFLEGPTEDTT
                     ALWQDVLELSKQEREAGGVLDMDTKIISTITSHGPAYLDKDKEKIVGFQTDKPFKRSLQ
                     PYGGIRMAIKACEDNGYKVDPEVVEYFTTHRKTHNAGVFDAYTPEMRACRSAHIITGLP
                     DAYGRGRIIGDYRRPALYGVDRLIEDKQEQLDSTRTIMYSDVIREREELSEQIRALKML
                     KELAKIYGCDISKPATNVLEAAQAVYFAYLAAVKEQNGAAMSLGRTSTFLDIYAERDLR
                     EGTFTEKEIQEIIDQFIMKLRCVKFARTPEYNSIFAGDPTWVTESIGGIGVDGRHMVTK
                     MSYRYLNTLNNIGAAPEPNLTVLWSVKLPENFKKFCAEISIKHSAIQYENDDIMRVVHG
                     DDYGIACCVSSMRIGKEMQFFGARANLAKCLLYAINGGVDEISGKQVGPKYRPITSEYL
                     DYDEVWDKYKDMMKWLAGVYVNALNIIHYMHDKYCYEKLQMALHDKQVRRWFATGIAGF
                     SVVADSLSAIKYAKVKPIRDENGITVDFEVEGDFPKYGNDDDRVDEIAKEVLHTFIKYV
                     KGNHTYRGGIATTSILTITSNVSYGKNTGATPDGRKKGVAFAPGANPMHGRDKNGAVAS
                     LASVAKMPFMDAQDGISNTFTIVPDALGKTEESSETNLVALLDGYAEKGGHHLNVNVLN
                     KETLLDAQKHPEEYPQLTIRVSGYAVNFIKLTKEQQDEVIARTFHELM"
     CDS             12246..12995
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 80.6;
                     E-value: 4.4e-25)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg27_16"
                     /sec_met_domain="Radical_SAM (E-value: 1.4e-32, bitscore:
                     103.9, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGYIHSLESFGTVDGPGVRFVVFFEGCPMRCQYCHNPDTWVLTDG
                     KQMEADEIIDRFLRNASFYRTGGITATGGEPMLQIDFLTELFAKAKAHGIHTCLDTSGI
                     MFPGFPEDGEATSDITLEKIDRLLDVTDLVMLDIKHIRDEDHRKLTGHSNKNILAFARY
                     LDQKKKPVWIRHVVVPGITFEKAELTELGHFLKTLSNMEKLEVLPYHALGKVKYDNLGM
                     DYVLKDTPQLTKEEAKKAEQMIRDAMS"
     CDS             12995..13135
                     /locus_tag="ctg27_17"
                     /transl_table=11
                     /translation="MASHYDIASLVKCVILIVPANDAHFYKNITGKYKYSEKYIKNDIL
                     Y"
     CDS             13211..13741
                     /locus_tag="ctg27_18"
                     /transl_table=11
                     /translation="MRIKITGRNIELTDGIKDAVEDKLNKLEKYFTPDTDVYVTLSVEK
                     ERQKVEVTIPMKGNYIRSEQVSNDMYVSIDLVEEVIERQLKKYRTKLVTKQQSAASVFK
                     QDFLDAASDDDEEIKIIRSKKFDMKPMYPEDACVQMELLGHDFFVFINAETEDVNVVYK
                     RKGNTYGLIEPEY"
     CDS             13759..13962
                     /locus_tag="ctg27_19"
                     /transl_table=11
                     /translation="LCCEYKEPTLRQTPCRRVGSLHNAFVAWSCASKGGSQLSGCQIAT
                     SRECFCDFGRKLENLSLPVYSQ"
     CDS             complement(14163..15014)
                     /locus_tag="ctg27_20"
                     /transl_table=11
                     /translation="MSVRIIVDSASDLTKERADALNLDYMPLKTIFGETEYLDGVTISH
                     KEFYEKLIECGTIPTTSQVSPHDFEAKFKEVKEAGDTAVVICLSSLLSGTYQSAHIALD
                     GYEDCITLVDSLNVCLGEQILVLYAVKLRDEGLSAKEIAEKLEEKKKDVCVLAVFDTLE
                     YLKQGGRISKTAAWAGNILSIKPVIAIEKGEVAILGKARGSKNGNNILIQEVKNKNGID
                     FSMPYMLGYSGLDDSLLRKYIADSADLWTGQTKELPISTIGSTIGTHAGPGAICVSFFH
                     NA"
     CDS             complement(15084..15656)
                     /locus_tag="ctg27_21"
                     /transl_table=11
                     /translation="MTSFLIYFSASRQCPRQAPFFLLFPVFPYRKRFLTHKILCLLLAS
                     FTIKPISTALRFLPSSVPAAATKISVFQSDPVFRSYSRTGISLQPHPHSVPRPPPAIFH
                     RAIHTALYLKCTACLFHSIVPDTFLRDPPESLPRYTFLPLSSALLYNFPLLHYCHAGID
                     TTQVSYVCRFLSTTFDFYFDTLIIKIS"
     CDS             15763..16770
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg27_22"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 8.9e-52,
                     bitscore: 166.1, seeds: 13, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_N (E-value: 7.4e-27,
                     bitscore: 84.5, seeds: 635, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIVVLAGGLSTERDVSFKTGDMVAKALRENGHQVILLDVFMGYS
                     DKKEDLTGIFDRSEEVSVKVSGIPEIAPDLAKVKASRKDQSDNFFGPNVIELCQMSDIV
                     FMALHGENGENGKIQAAFDLFGIRYTGTGYLSSALAMDKEMSKKLFLSAGIPAPKGASM
                     KKADCSDDITKLGIQFPCVVKPCCGGSSIGVSIAHNAEEYKAALDEAFRWEENLIVEEY
                     VKGREFSVGVIEGKALPIIEIAPVQGFYDYKNKYKAGSAVETCPAELSEAVTEKMQHYA
                     EQVAQVLGLDTYSRTDFLLDENENIYCLEANTLPGMTPTSLLPQEAQVVGVNFNE"
ORIGIN
        1 aagacattct gccggaacat aatgaaggga tgcatgtggt tccacagatt ctgacgaatc
       61 gtgcagaaga ttttctggca atcgcaaaag agttaggaaa ctatggttac gagagcgtca
      121 atttaaatct ggggtgcccg tccgggacgg tcgtggcaaa gcaccgcggc gcaggatttc
      181 ttgcggtgcc ggaggaactg gatcactttt tagaagagat ctttgcggaa tgtccgctcc
      241 ggatctccgt caaaacacgt gtcggtgtca atgatgccgg ggagtgggag catcttcttt
      301 ccatctatga aaaatatccg atggaggaac tgatcattca tccgcgtgta cagaaggact
      361 tttataacaa tactccggat atggaagcgt ttttatatgc ggtagaaaat agcagacata
      421 cgctatgtta caacggtgac atctgctccg tggaggatta ccggacatgg agacagcaga
      481 tggaagaaaa aaggaaatgt gcctttatgc aggaatccgg gcagcagacg gatccggagg
      541 acactggcag cctggtgtcc catctcatgc ttggaagagg agttttaaaa aatccgggtc
      601 tgatcggaga actcacagga catgcgccga tcacaaagga tcagtttcat gcgtttcatg
      661 atgacatatt aaaaggatat ctggatgtaa tgtcagggga gcgcaacacg ctgtttcgta
      721 tgaaagagct gtggttttat tttgcaaaat attttacaga acccgaaaaa tatgtaaagc
      781 agatcaataa gacacagcat gtggcggagt accgtgtgat tgttgataat ctgttccgcg
      841 agcaggaatg ggaacaaaaa taaaaagtaa aatattttat aaaaaagtaa aataaataat
      901 tgtaaaataa aaatgatttt gctattgtag agttagatat catacagaaa tggaggagcc
      961 gtatgagaaa acaaagcaaa atcatttttt atgcaggaat tgtattgggg gttgctgcag
     1021 tgcttacggg ggtggcactg tcggggggag agaagatccc gaaggatttt acagtgagtt
     1081 atgatggaat caaaacggcg gatattacgg cgggcgtcag tgtacatgat ccatccgtga
     1141 tagaggcgga cggtacctat tacattttcg gatcgcatat gtcaggggca tcatctgagg
     1201 atctgcggaa ctggacatcg atcggtgacg gatatacgca gtcgaatccg atctttgatg
     1261 atctgcttgg aacagagcat gtatttgatt atacgggaag cagagactct gtgataccga
     1321 ctgacgatgg gacttatcat gtctgggcac cggacgtggt ctataacagg gcacaggact
     1381 tatattatat gtatttctgt acgtcctcga catggaatgc atcgaatctg tgctatgctg
     1441 tttcagataa accggaggga ccgtatacat ggaagggagc actcatttat tccggattcg
     1501 cgaaagatac gatcggggca actgatgtgc tcgattatgt ggacatcagc tatgcaaaaa
     1561 agaactacat catcgcggga aataaatata actatgagaa atatccaaac gcaatcgatc
     1621 cgaccgtctt ttatgatgcg gacggaaaaa tgtggatggt ctatggctcn nnnnnnnnnt
     1681 cgtggtgggt tgtaattttc ctgttagaga ttgatgagaa aacgggattg gtcatccatc
     1741 ccaaagaaga tgagaaaaac ggcgtggatc cgtattttgg aaaacgcctg cttggcggcg
     1801 gacacaaatc gatcgaggga ccttacattc tctatgatga ggaaagcgga tattattatc
     1861 tgtttgtttc ctatggttcc ctgacgagag agggcggcta tcagatgcgt gtgttccgct
     1921 caaaaacggt ggatggagag tatgtcgata tgaatggggc atatccgggg atgtgggatg
     1981 acaatgcagc ttatggctta aaactttccg gcaattatta tctgccgggt cttaataagg
     2041 catatatggc gaccgggcac aattcagctt ttgtggatga agatggaaag aaatatattg
     2101 tataccacac gcgctttgac aacgggcagg agtatcatga accccgtgtg catcagtatt
     2161 tcctgaatca ggatggatgg ccatgtatgc ttccgtatgc gacagacggc gagacgatcg
     2221 cagaaagcgg ttatgacatt tcggaagtgg agggaactta ttatgtgatc aaccagggaa
     2281 ctgcgatcag tgccaggatt gcacagccag taaaactggt gctgatggat aacggaaacg
     2341 tgtacggcga aaatttagac ggtacctgga gtatggagga aggcacctgc tatatgacgc
     2401 tcacatacgg gggaaaagaa tataatggtg tattctgtca gatgaaagat gaggcaggca
     2461 cggatgtcat gacattttct gcggcaggag cagatgagag tgtctggggc gttaaatatt
     2521 ttgagtaaaa tgaaagcaaa gacgtgagaa acggcagacg gagcataaaa tacttgcaaa
     2581 gaactctttc ccatggtaat gtggtacgta tctaaagttt tgggaaagga acgggtacaa
     2641 atgttaaaag cgattgatga tttcgtctgg ggagttccac tgatcgtgtt gatcttagcg
     2701 gttggtatct ttcttacgat ccggctgcgt ggacttcaga tcacgaaact gccacttgcc
     2761 ataaaacata tggtggcaaa tgaaaaaaac ggagaacacg gggaagtttc aagtttcggt
     2821 gcactctgca cagcattgtc tgcaacgatc ggaacaggta acattgtcgg cgtggcaacc
     2881 gcgcttgtcg ccggaggacc gggtgcactg ttctggatgt ggatcgcagc actgcttgga
     2941 acggcgacga aatattccga gtgtctgctt gcaattaaat accgtgttgt ggcaaaggac
     3001 ggtcatatcg tcggaggacc gttttattac atcgaaaacg gaatgggtga aaaatggaaa
     3061 tggctcgcaa aaatttttgc atttttcggt gtcggagtag gtttacttgg aatcggaact
     3121 tttacgcaga tcaacgggat cacaagtgcc gtgaacaatt tctttgatcc gcagaataca
     3181 tggacagtgg aactgtttgg cagaacctat tcctggacgg ttgtgatcgc aggtattatt
     3241 ctgacactgt gtgtggcact ggttatcatt ggcggtatta agcgtatttc cacagtagca
     3301 caggttgtgg taccttttat ggcactgctt tatgtcgttg tggtactgat catactattt
     3361 acgcatctta gcgcaattcc gggagcaatc gtagagatcg tgcagagtgc atttggactt
     3421 cgtgcggctg caggcggaac ccttggatcg atcctgatcg ccatgcagat gggaattgcc
     3481 cgcggaatct tttcgaatga ggcaggactt ggcagtgcgc cgatcgcagc ggcagcggca
     3541 aagacaaatg agccggtgac acagggactt gtatccatgc tgggaacgat cattgacacg
     3601 gtgatcatct gtacgatgac cggactttcc atcgtgatca caggagcctg ggatatggga
     3661 ttagaaggtg tctctgtaac cacgaaagca tttcagatag gactgccatt cccggagcag
     3721 gtggcatctt ttgtgttaat gttatgtctt gtattcttcg catttacgac gatccttgga
     3781 tggaattatt acagtgaaaa atgtctggaa tatctggttg gggacaaaaa gactgtttta
     3841 aagggatatc gctggctgta tatccttgca gtgtttatag gaccatttat gacggtatct
     3901 gctgtatgga cgatcgcaga tatctttaac gggctgatgg cattgccgaa ccttgttgca
     3961 ctcgttgctt tgagtggggt ggtagttgca gagacgaaga aatactttga aaaacagaaa
     4021 tattagtgag aaataaaaaa tggcggaggc agagtgcttc cgctgttttt ttgcctggtg
     4081 atgtagtctg cgttttttga ttttagaaaa gtatataata ttttagtata atctatacaa
     4141 aacaaaaaat aaggagtata ctgtcataag aaagaaacag tacgaatgtc atcagagggg
     4201 aggatactgc atgtcagatg aaaaatcttt aaagtacaat gaaccgtgga ttttacagcg
     4261 tgcggatcca tatgtttacc gtcatacgga cggctcgtat tattttacgg cgtcggtacc
     4321 ggcgtatgac gggatcgtat tgagacgtgc cggaacactg gcggaacttt ccggggcaga
     4381 ggaagtcatg gtctggaaga aacatgagtc cggtccgatg agttatcata tctgggcacc
     4441 ggagatccac tatctgtttg gaaaatggta tatttatttt gcgggaggcg aggcggaaga
     4501 tatctggaag atccgtccat atgtgttaga gtgcagcggg gacgatccgc tgacggatga
     4561 gtgggtggaa cttggaaaga tgaaacgcgc agcggaggat gagttttctt ttgaggcatt
     4621 ttcgctggat gcgaccgtct ttgaaaataa aggtgaatat tattatgtct gggcagaaaa
     4681 ggtcggagtc ggcaaaatga tttcaaatct ctacattgca aatatggaat ccggtaatca
     4741 gttaaaaaca gtacagatac ttttgactac gccggattac gactgggagc ggaaaggctt
     4801 ctgggtcaac gaggggccgg cggtgatcca tcatgacgga aagctgttct taacttactc
     4861 cgcaagtgag acgggtgtgg attactgtgt gggaatgtta tccatcgatg aggatgcgga
     4921 cattttagat ccgcgtttgt ggaaaaaaga gcgttacccg gtattaaaaa cctgtgaaaa
     4981 actgggcatt tacgggccgg gacacaactc gtttaccgtg gatgaagatg gaaatgacgt
     5041 catggtctac cacgcacgga cggaggcaga aattaacgga gatccgttgt acaatccgaa
     5101 ccgtcatgcg atgcttatga aggtaaaatg ggatgaagcc ggaagaccgg tattttccta
     5161 tgaaaataaa taaaaaagga gagaaaacaa tggcaaaact gatcatcaat gaggaaaaca
     5221 aaaagagtcg tattgagccg gaaatctatg gacatttttc ggagcatctg gggagatgta
     5281 tttatgaggg aatttacgtc ggcgaaaaat cggagattcc gaatgtaaac ggcatgcgca
     5341 ccgatgttgt ggacgcatta aaggaattaa aagttccggt actgcgctgg ccgggtggct
     5401 gctttgcgga cgaatatcac tggatggacg gaatcggacc gaaggaaaag cgtaaaaaaa
     5461 tgatcaacac acactggggt ggtgttgtgg aagataacag tttcggaaca catgaatata
     5521 tggaactgtg ccgtcagatc ggctgtaaga cttacgttaa cggtaatctt ggaagcggaa
     5581 ctgtccgtga gatgtcagag tgggtggagt acatgacctt tgagggcgtc tccccgatgg
     5641 cagatttgag aaaagaaaac ggacatgagg caccgtggaa agtggattat tttggtgttg
     5701 gcaatgaaaa ctggggatgc ggtggaaata tgacgccgga atattatgca aatgagtacc
     5761 gcagatacca gacctatgtg cgcaattatc acccggaccg tccgatcaaa aagatctgct
     5821 gtggtgcaaa tgttgcagac tattactgga caaaaggtgt gttaaatacg gcatttgacc
     5881 atgccgagca gtggcacgga tttatggatg gtctatcact tcattactat gtacatccgg
     5941 agggctggga gatcaaagga agttctacgg attttgatgc ggatgtctgg tataagacat
     6001 tatcgaaggc gctttatatg gagacattga tcgaacgcca cggtgcgatt atggatgagt
     6061 acgatccgga taaaaaagtc ggtatgatcg tggacgagtg gggcacctgg tatacctgcg
     6121 agccgggcac caatccggga tttttgtatc agcagaatac ggtgcgtgat gcacttgttg
     6181 caggtatcac cttaaatatt tttaacaagc acagtgaccg tgtcaaaatg gctgcgttag
     6241 cacagatggt aaatgtttta cagtctgtac ttctgacaga gggcggccag atgataaaga
     6301 caccgaccta ccatgtcatg catatgtacc gccaccatca gggcgcagac ctgttagaga
     6361 gcactttgac cggggcaggt gagatcggac cggatgagtg gaaagtaccg aagatcacag
     6421 agtccgtatc catggataaa gacggtgtga tcaccgtcac catgaacaac ctctctgtgg
     6481 aggcatcgga aaaggtggag atccagcttg caaaccgtgg ctatcatgtg actgaggcaa
     6541 agatcgtaac cgattccgat atgcatgcac ataacacatt tgaggcaccg gataccgtga
     6601 cagaaaaaga ttttactgcc tatgaggaga cggaaaacgg cgtgaatgtc acaatgccgg
     6661 caaacagtgt gatcgagctg cgtcttgcaa aataagaaaa aaactgtcag aaatggcggg
     6721 aaaattagct gctggtcata ctggaaatat gaacagtaac gaaaattaca ggcggagatg
     6781 acatatggca cagatctgta aaaagtgtct gctgcgcgaa atggcggaag cggatgcaaa
     6841 aatgattgag aaatataaag aggcgatcaa aaaagaagat caggtatcag agagcgagta
     6901 tgagagacgg cttactgtct gcaaaacctg tgaactttta aacgcgggaa cttgcggtgc
     6961 gtgtggctgc tatgtagagc tgcgcgccgc ggcagccgta tcaaaatgcc catataaaaa
     7021 atggtgacag ttcagacgga ctgttaccat tttttattgc ggtaatatta cttcatttcc
     7081 tccaccgggg cgtacccgag actcactttg atatcctggc tgtaattgcc aaaagatttt
     7141 ccaaagatcg taagtccgcc gacgtgcctg gcatcgtcct ccacagccag gcggaagcgg
     7201 atgctgctgt ggcagttgag atggaaatca tcgattttaa cgtcggatat tttgagaccg
     7261 tcgatatagg tacctttttg attgatgaca agttgtttta gcaatccgta ctggttccag
     7321 tttgcatacc accagtccgg tgtcaacaga cccttcacat cgccaaaatc gccgggggag
     7381 gtccagtcac caatatgaat atcatttaag taaaaactga tatcggaagg ccagtcattg
     7441 ttggtgcctg gtgcttcgga actaagttct gcggaaattg tgatctgtgt gatttttttg
     7501 gaagccggga taaaatttgg aatggcatat tcaacataac cgcgtgtaaa ccatagaata
     7561 tcagcgttat agcggtctgg atgttcaaaa taccgcggat catccacttc accgatcagg
     7621 gcatctgcag aggcaagtcc gcaggtcggg cagatctggt aatttgtata gtgaccgact
     7681 tttaattctg tatgataaac attctcgatt tcggcaggct tttctaaatc gatcaggatc
     7741 ttatccaggt ggatggaaca gattttctgg ttgccgtgaa cagcagattc actggatgtt
     7801 gtgatcagtc cgcagttctc aagttttttg atatggctgg ttaaggcacc gtttgtaata
     7861 tttaaacggg aggcaagttc attcatgctc atattgtcgt tttccagcaa aatatttaaa
     7921 atttcaattc tcacatcaga accgagtgcc ttaaaaagtt ctaacccttc attcaacgaa
     7981 gtgatgtgta acaaggaaat cctctccttt caaaatctgt aaaaatcaca gaatgacacg
     8041 ttctaaactg taatcattgc ctgaaactgt caggattgca agacttttcg aatctccacg
     8101 tccgtcactg gcactgcccg gattaatata aactttattg aaacgttcat aaaatgtata
     8161 gtgatgagta tgaccaaaga taagaaaatc agcatctgtc aggtcaaatg gaagatcaaa
     8221 ctgattatga accagaaaaa aagtcttgcc gccaatgcgg aactgtaaaa attcaggaag
     8281 attttttgcc cagtcaccgc ggtcattgtt gcctcggacc atataaagcg gaatgccaaa
     8341 gttccggaaa cagtcataat ttttctgcgt acagaaatcg cctgcatgga tcagataatc
     8401 gcagctgtct aaataacggt gccactcttc acgaaaaata ccgtgtgtat cagaaataat
     8461 gccaattttc ataaaattct ccattcttgc gtgaaaaatg ttattttcat actaattttc
     8521 tccattaagt aaaaaaataa ttagataaat tatataggaa aaaagtatgg aagtctagaa
     8581 gaaagaaaaa tattcataaa aatacttttt tattttaaag taatgtagta tactgttcgg
     8641 gggatcaatt agttaatttt ttaacgggag agggagaatg gaaaactcgg tattggagga
     8701 aaaggttttt cataaagtta tgaaaaacgt accgtttggt cttgttgtga gcagtgaggg
     8761 cagaaaacgc aaggtgtatt atgtgaatac gatggcgtac catatgctcg gttacacgcg
     8821 ggaggaattt attgaaaaag tacaggacgg ctggagccgg tttgtggata ttgacttaag
     8881 aacggtcatg agggagcatc atgaagagat tctgacaggg gagtcatttg agctgactgc
     8941 tcagacagag acgaaagacg gaaataaaaa gtggctgtct tttcgtgtga tggtatccat
     9001 ggatgttata tcctcgcagt taaaaccggt cagttatatt acgatcacag atgtaacgga
     9061 gaaagtggaa aaaaacagac gttacgcgag agaaagagaa tatttacggg attgtgcagc
     9121 cagagattcc atgacgagac tgttaaaccg tggtacgatg gaagatcgta tcaaagaaga
     9181 actggagtca gtggcagaag gacaaaatta cgcatacatt gctattgatc tggataattt
     9241 taagcaggtc aatgatgtgt atggccactg ggttggcgac cgcgtcatta tgagtatgtc
     9301 taatatttta agggaagtct acggtaatca ggtcagcatt ggacgtatgg gcggggatga
     9361 attcgcagta tttcttccgg atgtaaaaga ccgtatgtgg atacaggggc aggcagatga
     9421 agtgctgtac cggctgcgca gacaaaaaga aatgatcgga atggcggagg agccgacagc
     9481 aagtattggc atcgcattcg gccctgagga tggcacaagc ttccgtgaac tgtatcacag
     9541 agcggatgca gcactctatc aggtcaaaaa ggaagaaaaa aacagcatag caatttacac
     9601 aatgatataa gttttttttg gtacatttta cctattgaaa aaatgaatca aaaattataa
     9661 catctaattg ttatatgact gacggaaaaa gtggaagaac cacatgaagt ataacgttta
     9721 caatgccgac cgtctgggcg agataacccg gactgtcggt ttcttttatt cttaaagata
     9781 ttcttcttac aggaatcctt ttgtatgaaa aaaagaacag ttccggaaac gaagcggata
     9841 ttgacaagca gtgatgaaac atgatatatt cactgcgtta gaactagcta acaaaagtta
     9901 gaaataacta ccaatatttt ccagcaatac caaaatattg ggggatcaga tccgttttat
     9961 acaggtaaac catagttttc agcaaacagg aggaaaaata atgcaaaacg aatggagaga
    10021 ttttaatggt ggagcatggg agaatgaagt aaacgtcaga gacttcatcc agagaaacta
    10081 taagccatat gatggtgaca gctctttctt agagggaccg acagaggaca ccacagcact
    10141 ctggcaggat gtacttgagc tttcaaaaca ggagagagag gccggcggcg tactggatat
    10201 ggatacgaag atcatttcca cgatcacttc ccatggacct gcgtacttag acaaagataa
    10261 ggagaagatc gtaggtttcc agacagataa accattcaaa cgttccttac agccttatgg
    10321 cggtatccgt atggcaatta aggcatgtga agataatggg tataaagtag acccggaagt
    10381 ggtagaatat ttcacaacac acagaaagac acacaatgcg ggtgtgtttg acgcttatac
    10441 accggagatg agagcctgcc gttccgcaca tatcatcacc ggacttccgg atgcatacgg
    10501 gcgcggacgt atcatcggcg actacagaag acctgcactt tacggtgtag accgtctgat
    10561 cgaagataag caggagcagt tagattccac acgcaccatc atgtattccg atgttatccg
    10621 tgagcgtgag gagttatccg agcagatcag agcccttaaa atgttaaaag aattagcaaa
    10681 gatctatgga tgcgatattt ccaaaccggc aacaaatgtt cttgaggcag cacaggctgt
    10741 atattttgcc taccttgcag cagtcaaaga gcagaacggt gcggcaatga gtctaggacg
    10801 tacctctacg ttcttagaca tctatgcaga gcgcgacctt cgtgagggta cattcacgga
    10861 gaaagagatt caggagatca tcgaccagtt catcatgaaa ctgcgctgcg taaaatttgc
    10921 ccgtacaccg gagtacaaca gtattttcgc cggagatcct acctgggtaa cagagtctat
    10981 cggtggaatc ggagtagatg gaagacatat ggtaaccaag atgtcttacc gttatttaaa
    11041 taccttaaac aacatcggag cagcaccgga gccaaacctg actgttttat ggtctgtaaa
    11101 acttccggag aactttaaaa agttctgtgc agagatctca atcaaacatt ctgcgatcca
    11161 atatgaaaat gatgacatca tgcgtgtggt tcatggtgat gactacggta tcgcatgctg
    11221 cgtatcttcc atgagaatcg gaaaagagat gcagttcttc ggagcccgtg caaaccttgc
    11281 aaaatgttta ctctatgcga tcaacggtgg tgtggatgag atcagcggca aacaggtagg
    11341 accgaaatat cgtccgatca cttccgagta tcttgactac gacgaggtat gggataaata
    11401 caaagacatg atgaaatggc ttgcaggtgt ctatgtcaat gcattaaaca tcattcacta
    11461 tatgcatgac aaatactgct atgaaaaact gcagatggcg ctgcatgaca aacaggtaag
    11521 acgctggttt gcaaccggta ttgcgggatt ctccgtagta gcagattccc tgtctgcaat
    11581 caaatatgca aaagtaaaac cgatccgtga tgagaacggc attactgtag attttgaggt
    11641 cgagggagat tttccgaaat atggtaatga tgatgaccgt gtggatgaaa tcgcaaaaga
    11701 ggttcttcat acctttatca aatatgtaaa aggaaatcac acctatcgcg gtggtatcgc
    11761 aacaacttcc attcttacca ttacatccaa tgtatcctat ggtaaaaata caggagcaac
    11821 cccggatgga agaaagaaag gtgttgcatt tgctccgggt gcaaatccaa tgcacggacg
    11881 tgataaaaac ggtgcggttg cttccttagc ttccgttgca aaaatgccat ttatggatgc
    11941 gcaggatggt atttccaaca cctttaccat cgtgccggat gcacttggaa agacggagga
    12001 aagctctgaa acaaaccttg tggcactgct tgacggctat gcagaaaaag gcggtcacca
    12061 cttaaatgta aacgtattaa ataaggaaac actgcttgat gcacagaagc atccggagga
    12121 atatccgcag cttacgatcc gtgtatcagg ttatgcagta aacttcatca aactgacaaa
    12181 agagcagcag gatgaggtaa ttgcaagaac tttccatgaa ttgatgtaat aataaggaga
    12241 ttattatggg ctatattcat tctctggaat catttggtac cgtggacggt ccgggggtgc
    12301 gttttgtcgt attcttcgag ggctgcccga tgcgctgcca gtattgccac aacccggata
    12361 catgggtgct gactgatgga aaacagatgg aggcggacga gatcatcgac cgcttcctgc
    12421 gcaatgcctc gttttaccgg actggcggaa ttaccgccac cggtggcgag ccgatgcttc
    12481 agattgattt tctgacggaa ctgtttgcga aggcaaaggc acacggaatc catacctgtt
    12541 tagatacgtc tggtattatg ttcccgggat ttccggagga tggagaagcc acatcagata
    12601 tcacactgga aaaaatagac aggcttcttg atgtcacaga tcttgtaatg cttgacatta
    12661 agcatatccg tgacgaggat caccggaaac tgaccggaca ttcaaataag aatattctgg
    12721 catttgcaag atatttagat cagaagaaaa agccggtgtg gatccgtcat gtcgttgttc
    12781 ccggcattac atttgagaag gcagaattga cggaactcgg acactttcta aagacacttt
    12841 ccaatatgga aaaattggaa gtactgccat atcatgcact tggcaaggtc aagtatgata
    12901 atcttggcat ggattatgtg ttaaaagata caccgcagct taccaaagag gaagcaaaaa
    12961 aagcggaaca gatgataagg gatgcaatgt cataatggcg agtcattatg acattgcatc
    13021 ccttgttaaa tgtgtaatat tgatcgtgcc agcgaatgat gcacattttt acaagaatat
    13081 tacaggaaaa tataaatatt ctgaaaaata tataaaaaat gatatattgt attgaaatat
    13141 ttgtggaaag tgctataata aaaccatgat ataaatctgt atcaaataaa cggcaaaggg
    13201 gttggacatc atgagaatca agattacagg aagaaacatt gaattaaccg atggtatcaa
    13261 agatgcagtg gaggacaagt taaacaaatt agagaaatac ttcactccgg acacagatgt
    13321 ctatgtaaca ctgagcgtag agaaggaacg ccagaaagtg gaagttacga ttccaatgaa
    13381 aggaaactat attcgttctg aacaggtcag caatgatatg tatgtatcaa ttgatctggt
    13441 agaagaggtt attgagcgtc agttaaagaa atatagaacg aaactggtta cgaaacagca
    13501 gagcgcagca tccgttttca aacaggattt cctggatgca gcatcagacg atgatgaaga
    13561 gatcaagatc atccgttcta agaagttcga tatgaagccg atgtatccgg aagatgcatg
    13621 tgtacagatg gagttattag gacatgactt cttcgtattt atcaatgctg agaccgaaga
    13681 tgtcaacgtt gtatacaaga gaaaaggcaa cacatacgga ttgatcgaac cggaatacta
    13741 aaatggatca ttgcagaatt gtgctgtgaa tacaaagaac ccaccctgcg gcaaacacct
    13801 tgccgccggg tgggttcttt acacaatgca tttgtagcgt ggagttgtgc gtcaaaaggt
    13861 ggttcacagc ttagtggttg tcaaattgca acaagccggg aatgcttttg tgactttgga
    13921 agaaaattag aaaatcttag cctgcctgtc tattcacagt gatgttctgc cacggatggc
    13981 agaacaaggc ttcacgagcc atggaaggct cgttgaacgc cgttcacgtc actctgagaa
    14041 aatctgactc aggcaagctt agattttgtt attttcgtac aacggaacaa aacaaccccg
    14101 gcttgttgta atttgacaga caaaaaacta aaatccacct tttgacacac gagattcctg
    14161 ccttaagcat tatggaaaaa cgacacacag atggctcccg gtcccgcatg tgtaccgatc
    14221 gtactcccaa tcgtgctgat tggcagctct tttgtctgtc cggtccagag atctgcgctg
    14281 tccgcaatat acttccggag cagtgagtcg tcgagcccgc tgtagcctaa catatacggc
    14341 atggaaaaat cgataccgtt tttatttttc acttcctgga tcaggatgtt atttccgttt
    14401 ttcgatcctc tggcctttcc taagatcgca acctcacctt tttcaatggc gatgacaggc
    14461 ttgatggata aaatatttcc cgcccaggcg gcagtctttg agatgcgtcc gccctgtttt
    14521 aaatactcaa gggtatcaaa gacggctaag acacagacat ctttcttttt ctcttcgagt
    14581 ttttcggcga tctctttcgc agaaagcccc tcatcgcgca gctttacggc ataaaggaca
    14641 aggatctgtt cgcccagaca tacatttaaa ctgtcaacta atgtgataca gtcctcatag
    14701 ccatcaagcg caatgtgtgc actctggtat gtaccggata aaagagagga cagacagatc
    14761 acaacggcgg tatcgccggc ttcttttact tctttgaatt tcgcttcaaa atcatgtgga
    14821 gatacctggc tggtcgtcgg gattgttcca cattcgatca gtttttcata aaattcttta
    14881 tgggaaatgg taacaccgtc taaatattcc gtttcgccaa aaattgtttt taaaggcata
    14941 taatcaagat ttaatgcatc cgcacgttcc tttgtgagat cagatgcgga atcaacaata
    15001 attcgtacac tcattttttt ccctccggat aaaatagttt gactatcaaa caaaaataaa
    15061 tataaagtat gatgaaaaga atgtcaagat attttgatta tcaaagtatc aaaataaaaa
    15121 tcaaatgtag ttgacaaaaa tcgacagaca taagatactt gtgtagtatc aatgcctgca
    15181 tgacagtagt gtaaaagtgg aaaattatat aacagagcag aagaaagcgg aagaaatgta
    15241 taacggggca gagattctgg tggatctcgc aagaaggtat ccggaactat ggaatgaaat
    15301 agacaggcag tgcactttaa atagagagcg gtatggattg ctctgtgaaa tattgctggc
    15361 gggggacgag gaacgctgtg aggatgtggt tgcaaagata taccggtacg ggagtatgat
    15421 cggaaaacag gatctgattg gaagacagat atttttgtgg ctgctgcagg cactgaggat
    15481 ggaagaaatc gcaatgctgt agaaatgggt tttatcgtga aagaggccag cagcaggcaa
    15541 agaattttat gagtcaggaa tcttttccgg tacgggaaaa cggggaataa aagaaaaaat
    15601 ggtgcctgcc gggggcattg ccgtgaggca gaaaaataaa taagaaagga tgtcatgcag
    15661 gcataaaaag tacaaaggaa tgtgcaaatt ccttgccaca caaagaaaaa aggtatacta
    15721 taaagcagaa atgtttttat gagatagtaa ggagagtata ccatgaagat tgttgtttta
    15781 gcaggtggtt taagtacaga gagagatgtt tcctttaaga ccggagatat ggtggcaaag
    15841 gcattgagag agaatggaca tcaggtaatc ttacttgatg tatttatggg atacagtgat
    15901 aaaaaagaag atctgacagg tatttttgac cggagtgagg aagtcagtgt aaaagtatcc
    15961 ggaataccgg aaattgcacc ggatcttgca aaggtaaaag catccagaaa agatcagtca
    16021 gacaatttct ttggaccgaa tgtgatcgaa ttatgccaga tgtccgatat cgtttttatg
    16081 gcactgcatg gagaaaacgg agaaaacggc aagattcagg ccgcatttga tctgtttggc
    16141 atccgctata caggaaccgg ttatttaagc agtgcgcttg ccatggataa ggagatgtcc
    16201 aaaaaattat ttttgtcagc aggcataccg gctccaaagg gcgcatccat gaaaaaggct
    16261 gactgcagcg acgatatcac aaaacttggc attcagttcc cgtgtgtggt aaaaccatgc
    16321 tgcggaggtt cgagtatcgg tgtttccatc gcacacaatg cggaggaata taaagcagca
    16381 ttagatgagg cgttccgctg ggaagaaaac ctgatcgtgg aagaatatgt aaaaggacgt
    16441 gagttttctg tcggcgtgat cgagggaaaa gcacttccga tcatcgagat cgcaccggta
    16501 cagggatttt atgattataa gaataaatac aaagcaggca gtgctgttga gacctgtccg
    16561 gcagaacttt cagaagctgt tacagagaaa atgcagcatt atgcagagca ggtggcacag
    16621 gtacttggat tagataccta ttcccgcacc gattttctgt tggatgaaaa tgaaaatatc
    16681 tactgtctgg aagcaaacac attgccgggt atgactccga caagtcttct tccacaggag
    16741 gcacaggttg tcggtgtgaa ctttaacgaa
//
