LOCUS       c00070_gnlPro..        10057 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NKCCFMNO_70.
ACCESSION   c00070_gnlPro..
VERSION     c00070_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 04:53:15
            Original ID  :: gnl|Prokka|NKCCFMNO_70
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10057
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10057
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[7091:10035]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      7092..10035
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..10057
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..10057
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             551..1399
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP_bind_3"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg70_1"
                     /sec_met_domain="ATP_bind_3 (E-value: 5.1e-08, bitscore:
                     21.6, seeds: 28, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKLEHLKEYLKGLGSVAVAFSSGVDSTFLLKVAHDVLGDKAIA
                     ITAQSCSFPKRELNEAKAFCEKEGIQHVICQSEELEIEGFSKNPPNRCYLCKKELFEKI
                     GDIAKKNGIEYIAEGSNMDDNGDYRPGLIAVKELGVKSPLCEAKLTKAEIREYSKELGL
                     PTWDKQSFACLSSRFVYGETISEEKLGMVEKAEQLLLDYGFHQVRVRIHGSLARIEIMP
                     EEFPKLLEKNVREDIAKKFKEYGFTYVTMDILGYRMGSMNETLGENDKTTADSSLKGKN
                     E"
     CDS             1396..3183
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M24"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg70_2"
                     /sec_met_domain="Peptidase_M24 (E-value: 3.2e-43, bitscore:
                     136.5, seeds: 437, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVKERIAALRARMKETGIDAYLIPTDDFHGSEYVGEYFKCRKYI
                     TGFTGSAGTAVIMQDMAGLWTDGRYFIQAADQLEGTGITLFKMGEPEVPTVHEFLKKNL
                     TQGRCLGFDGRTVSAKEAAELEKMLDENGVSLSVDHDLAGDIWENRPVLSCEPVTELDI
                     KWAGESRADKCARIRKAMEKKGADLFVLTSLDDIAWLLNIRGGDIHCCPVVLSYLVMTK
                     TEIRLFANEKAFQTDVLEALEKDGVTLFPYDGIYEYVKTFKKDKKVLLCKKKVNSRLVS
                     NIPADTRILDEENLTLLPKATKNPVEVENERIAHIRDGVAVTKFIYWLKKNVGRIPITE
                     LSAAEKLYEFRSEQEDFIDNSFDPIIAYGKHAAIVHYFATPETDIPLEPSGFLLADTGG
                     HYKEGTTDITRTVVMGPTTEEEKKYFTAVLRGTLNLGAARFLHGCTGVNLDILARQPLW
                     EMGENFKHGTGHGVGYLLNVHEGPNSFRWKIVPGGNAVLEEGMITSDEPGYYREDGFGI
                     RHENLMVCKKAEKTEYGQFMCFEFLTMVPFDLDGVVPELMSARERNLLNDYHAQVYEKI
                     SPYLNEEEKEWLKDATRAI"
     CDS             complement(3271..5037)
                     /gene_functions="resistance (resist) ABC_efflux (Score:
                     283.7; E-value: 1.8e-86)"
                     /gene_kind="resistance"
                     /locus_tag="ctg70_3"
                     /transl_table=11
                     /translation="MSRLTIKDPAKSKSSETFLKVLRFIGRYRFLLILSIILAAVSVIL
                     QLYVPILFGNAIDQVIAQHQVNFEMMWYYLSRILVMVILSSAATWLMNVINNRMTYQTV
                     KDIRAKAIRHIQVLPLSYLDGHSTGDIISRIIADTDILSDGMLLGFTQLFSGIVTIIGT
                     LIFMFSKNFWITLMVIVLTPVSFLVAKFISSHTFQMFRKQSDARGRQTALIEEMIGNQK
                     VVQAFGYEEKSSERFAKVNEELQECSLKAVFYSSLTNPSTRFVNNVIYACVALVGTFII
                     PGGRLTVGGLSVLLSYANQYMKPFNDISSVVTELQNALACAGRIFDLLEEEPEVAEASE
                     TLKDVKGEVDIKNVCFHYDESKKLIEDFNLHVKPGMRVAIVGPTGCGKSTFINLLMRFY
                     DVNFGSISVDGKPIRDITRHSLRSSYGMVLQETWIKNGTVRDNISIGKPEATDTEIIEA
                     AKLTHSWEFIRRLPKGLDTMLNEDSLSQGQKQLLCITRVMLCLPPMLILDEATSSIDTR
                     TELQIQEAFERMMEGRTSFIVAHRLSTIRNADLILVMKDGSIIEQGTHDELIAKGGFYH
                     TLYNSQFAKVSE"
     CDS             complement(5034..6848)
                     /locus_tag="ctg70_4"
                     /transl_table=11
                     /translation="MRSLTVYLKNYKKESILAPFFKFLEVVFDLIVPIVIAQIIDVGIA
                     NHDNGYIVQRFSILILMAALGLASTITAQFFAAKASVGFATELRQAVYDHVQHLSYTEL
                     DTLGTDTLITRLTDDVNQIQNGLNMGLRLLLRSPFIVLGSMVMAFTIDFKCALVFAVAI
                     PFLFLVVFVIMFLSIPLFKKVQGKLDTVTGLTRENLTGVRVIRAFCREKEAVAEFDTRN
                     QELTKLNLFVGKLSALLNPVTYVLINIATVILIQKAGVEVNLGGMQQGQVVALYNYMAQ
                     MIVELIKLASLIITLNKSAACAGRVADILKVKSTMDYPSSSTYSAQISKDLATATADAS
                     LSENAIVFNDVTFEYSKAGAPSLSHISFSVKKGQTVGIIGGTGSGKTTLVNLISRFYDA
                     SKGTVLLDGQNIENYTRSDLRSRIGVVPQKAALFKGSIRDNLKWGREDASDEDLWQALT
                     TAQGKEVVEGKPGQLDFMLEQNGKNLSGGQKQRLTIARALVKKPEILILDDSASALDFA
                     TDAALRKSLNRLDWKVTTFLVSQRSSSIQQADLILVLDNGTLAGKGTHAELLRTCDTYR
                     EIYFSQFPEERARYSSVSAGNIMKEVTV"
     CDS             7092..8363
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg70_5"
                     /sec_met_domain="HGD-D (E-value: 1.7e-56, bitscore: 180.9,
                     seeds: 370, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIIETFGHYVENLTDKKPQSARRLLKTGWEAQNLKFRYMQDKRL
                     MPADRHLANLMMDTMLRPLQKPEDSVIVSIFTPCEMMQEVGLHPYNVEGFSCYLSASKA
                     ERTFLQQAENQGIAETLCSYHKTFLGAAQKGLLPKPKCIVYTNLTCDANLLTFRTLADF
                     YQVPVFAIDVPWNQTTENVQYVADQLKDLKIFLEKNTGKTISEDRLKERLACSKRTLEN
                     YKKYQQMRADRYVPSDLVTPLYAGMTNNILLGTAEEEKYTQMLLEDIKKAPAAKGKHIY
                     WMHTIPFWSDAVRQELCFSEKAQIVGCELAETCEPDFDPENPFEAMAERMVYHSLNGSA
                     LRRIEAGIRHAKQAGADGAVWFGHWGCKHTLGAAQLAKKKFEEAGLPLLILDGDGCDRS
                     HGGEGQTSTRLGAFLEMLGGAENE"
     CDS             8356..10035
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg70_6"
                     /sec_met_domain="HGD-D (E-value: 8.1e-18, bitscore: 53.8,
                     seeds: 370, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 5.6e-66, bitscore:
                     211.4, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTYYVCKYTPIELLESLGGECENFNHMPEGFDLADQVSHPNIC
                     GFGKTLLEGVMEGKIKELVLVSCCDTIRSVYDILLESGKLDFLYILDVLHCDSACSRER
                     MAVQLKGLAKAYAQYKGTEFDAGKFRAAFHAQEKITKSHIAVLGARMGQELFEMTSKAM
                     PLPVENDTCVHNRSVGNILPPEGASFDELMDWYAGEILGQIPCMRMMDPTGRKKLYNDP
                     SVAGIIYHTVKFCDFYSFEYAEIKNHTDVPLLKIESDYTIQSSGQLLTRLEAFAESIQP
                     ETLEQTIDGDTKGERKMGKGYFAGIDSGSTSTDVVILNKDHEIVTSIILPTGAGAAIGA
                     DRALAEALKEAGLQREDIDALVTTGYGRTAIKNGDKSITEITCHARGAHFLNPEVRTVI
                     DIGGQDSKVIRLDENGAVANFVMNDKCAAGTGRFLEMMARTMEMNLDQMSECGLEFKED
                     ITISSMCTVFAESEVVSLIAQNKATDDIVHGLNKAVAVKTAALTRRVGGEEKYMMTGGV
                     SKNKGLVKTLEEKLGTKLVISDKAQLCGALGAALFAADMADV"
ORIGIN
        1 tttaaccgag tatttaaaga aagatataaa atatcaccga gtgattatcg gagtacttgt
       61 gtgaaagaga tgttgtcata acatatagat taataaattc aataaaaatc tgattatcag
      121 tctgaaataa gtatctctgg gtgttattta taatatgggg tagtggttaa ttattatgtc
      181 atgtatgaat ggagaagaaa caaacggaga actgcttcag aaaaagaagt agacaaactg
      241 taaataaaga agttaagaga ggctgttact ttagaaacta tttaaagaag taatagaagt
      301 cggggaagcg ttagaaaaga tacaagaaac ataaatcaat attgttcgtt ctattttcag
      361 taacacattt cgcaatgcga aaaataggtt gctgaacagt cgttgcctat attataatga
      421 agctatagca ccctgttaaa taatacattt gagaaagttc aactttcacg ctttgttgag
      481 ccagatcaat atacattatt tacgaggagt gctacaggta caataaaaaa cggacaagag
      541 gcagactgat atggaaaata aactagaaca tttaaaagaa tatctgaagg gacttggcag
      601 tgtagcagtt gctttctcaa gtggagtgga ttctacattc ttattaaaag tagctcatga
      661 tgtgctgggt gataaggcga ttgcgattac ggctcaatcc tgttctttcc cgaaaagaga
      721 gctgaatgaa gcgaaggcat tctgcgagaa agaggggatt cagcatgtga tctgccagtc
      781 tgaggaattg gagattgaag gattttcaaa gaatcctccg aacagatgtt atttatgtaa
      841 aaaagaactg tttgagaaga ttggcgatat tgcaaaaaag aatgggattg aatatattgc
      901 agagggatca aatatggatg ataacggcga ttacagacca ggtctgatcg ccgtaaaaga
      961 acttggagtt aagagcccgc tatgtgaggc gaagctgacg aaagcggaga tcagagaata
     1021 ctcaaaggaa ctggggcttc cgacttggga caaacagtca tttgcctgtc tgtcctccag
     1081 gtttgtctat ggagagacca tcagtgagga aaagcttgga atggttgaga aagcagagca
     1141 gcttttactt gactatggat tccatcaggt acgtgtccgt attcacggtt cacttgcaag
     1201 aattgagatc atgccggagg aatttccgaa acttctggaa aaaaatgtcc gagaggatat
     1261 tgcaaagaaa tttaaggagt atggattcac ttatgtgacc atggatattc tgggatatcg
     1321 tatgggaagt atgaacgaaa cacttggcga aaatgataaa acgactgcag atagcagcct
     1381 taagggtaaa aacgaatgac agtaaaagag agaatagcag cacttcgtgc acgcatgaaa
     1441 gaaacaggaa ttgatgcata tctgattcct acagatgatt ttcatggttc agaatatgta
     1501 ggtgaatatt tcaaatgcag aaaatatatc acaggattta ccggttctgc aggcactgcg
     1561 gtgatcatgc aggatatggc aggattatgg acggatggac gttattttat ccaggctgca
     1621 gatcagctgg agggaacagg aattacttta tttaaaatgg gtgaaccgga agttcccaca
     1681 gttcatgaat ttctgaaaaa aaatctgaca cagggaaggt gtctgggatt tgacggacgt
     1741 actgtcagtg caaaagaggc agcagaattg gagaaaatgc tggatgaaaa cggtgtgtct
     1801 ctcagtgttg atcacgatct ggcaggcgat atatgggaaa accgtccggt actttcctgt
     1861 gaaccggtta cagagctgga tataaaatgg gcaggagaat ccagagctga taaatgcgca
     1921 agaatccgca aagcaatgga gaagaagggt gcagatttat ttgtactgac ttctctggat
     1981 gatattgcct ggctgttaaa tatacgtggg ggagatatcc actgttgtcc ggtggttctt
     2041 tcttatcttg taatgacaaa aacagagatc agactttttg caaatgagaa agcctttcag
     2101 acagacgtac tggaagcgct ggaaaaagat ggtgtgaccc tttttcccta tgacggtatc
     2161 tatgagtatg tgaaaacatt taaaaaggac aaaaaagttc ttctctgcaa aaagaaagtc
     2221 aacagtcgtc tggttagcaa tattccggca gacacccgga ttctggatga agaaaatctt
     2281 acacttcttc ccaaggcaac gaagaatcct gttgaggtgg aaaatgaacg cattgcgcat
     2341 atcagagacg gagttgcagt tacaaagttc atatactggt taaagaagaa tgttggaagg
     2401 attccgatca cagaattaag tgcagcagaa aagctgtatg aattccgttc ggaacaggag
     2461 gatttcatag ataacagttt tgatccgatt attgcctatg gaaagcatgc tgctattgta
     2521 cattattttg caacacccga aacggatatt cctctggaac catccggctt tcttctggca
     2581 gatacaggag gacattataa agagggaact actgatatta cccgtactgt tgtcatggga
     2641 ccgactactg aggaagagaa aaagtacttc acagcagttt tgcggggaac tctgaatctg
     2701 ggagctgcca gatttcttca tggctgtacc ggtgtaaatc tggatattct ggcgagacag
     2761 ccgctatggg aaatgggaga gaattttaaa catggaaccg gtcatggagt aggatatctt
     2821 ctgaatgtcc atgaaggacc caatagcttc cgatggaaaa ttgttccggg tggaaatgca
     2881 gtgctggagg agggaatgat cacctctgat gagccgggat attacagaga ggatggattt
     2941 ggaatccgtc atgaaaatct gatggtctgc aaaaaagctg aaaaaacaga gtatggtcag
     3001 tttatgtgtt ttgaatttct aactatggta ccttttgatc tggatggagt ggtgccggaa
     3061 ctgatgagtg cccgggaacg taaccttctc aatgattacc atgcacaggt atatgagaag
     3121 atttctccgt atttgaacga agaagaaaaa gaatggctga aagatgctac ccgagcaatc
     3181 tgataaaaat aaaaaaatat tttacaaaat caaaaagagg aacagccgtg atggacagct
     3241 gttccttttt gatttattat ctggcttgtt ttattcagaa acttttgcaa actggctgtt
     3301 atataaagta tggtaaaatc caccttttgc aatcagctca tcatgagtac cctgctcaat
     3361 gatacttccg tctttcataa caagaatcag atctgcattt cggatggttg aaagcctgtg
     3421 agctacgata aagcttgttc ttccctccat cattcgttca aacgcttcct gaatttgtaa
     3481 ttctgttcgt gtatcaatac tggaagtggc ttcatccagg atcagcatcg gaggcagaca
     3541 gagcataact cgtgtgatac acagcagctg tttctgtccc tggcttaagc tgtcttcgtt
     3601 gagcatggtg tccagtcctt taggaagcct ccggataaat tcccagctgt gggtaagctt
     3661 ggctgcttcg atgatttcag tatctgtagc ttccggtttt ccaatcgaga tattgtcgcg
     3721 gacagttccg tttttgatcc atgtttcctg aagcaccata ccatagctgc ttctgagaga
     3781 atggcgggta atgtctctga tcggtttgcc gtcaacggaa atagatccga aatttacatc
     3841 atagaatctc atcagaaggt tgataaaggt tgacttaccg catccggtag gtcctacaat
     3901 ggcaacgcgc atacctggtt ttacatggag attaaagtcc tcaatcagtt tctttgattc
     3961 atcataatgg aagcacacat tcttaatatc tacttcaccc tttacatctt tcagtgtctc
     4021 agaagcctct gcaacttccg gttcctcctc cagcagatcg aagattctgc ctgcacaggc
     4081 aagagcattc tgaagttctg taacaacgga actgatatca ttgaatggtt tcatatactg
     4141 gttggcatag gagagaagta cggaaagtcc tccgactgtc agtctgcctc cagggataat
     4201 gaatgtaccc accagtgcaa cacaggcata aataacatta ttgacaaaac gggtggaagg
     4261 gtttgtcagg ctgctgtaaa aaacagcctt cagactgcat tcctgtaatt cttcgttaac
     4321 ctttgcaaag cgttcagaag atttttcctc atatccaaaa gcctgaacaa ccttctggtt
     4381 tccaatcatc tcttcgatga gagcagtctg acgtcctctg gcatcgcttt gcttccggaa
     4441 catctggaag gtatgggaag aaataaattt ggccaccaaa aagcttacgg gggtcaggac
     4501 aatgaccatc aatgtaatcc agaaattttt ggagaacatg aagatcagtg ttccgatgat
     4561 cgttacgatt ccggaaaaaa gctgggtaaa tccaagcagc ataccatcgg atagaatatc
     4621 tgtatctgcg ataatacggc tgatgatatc tccggtactg tgtccgtcaa ggtaagagag
     4681 gggaagtacc tgaatgtgtc ggatggcttt ggcacggata tcctttactg tctggtaggt
     4741 catgcggtta ttgatcacat tcataagcca cgtggcagca gaagagagga tgaccattac
     4801 aaggatacgt gacaggtaat accacatcat ttcgaagttt acctgatgtt gggcaatgac
     4861 ctgatcaatg gcatttccga ataggattgg gacatacagc tgaaggataa cggaaactgc
     4921 tgccagtatg atactgagga tcagcagaaa acggtatctt ccgatgaaac gcagtacttt
     4981 aagaaaagtt tcgctgcttt tgcttttagc aggatctttt attgttaatc tgctcataca
     5041 gtcacctcct tcattatatt acctgcagat acagaggagt atctggctct ttcttccgga
     5101 aactgagaga agtagatttc ccggtaagta tcacaggtac gtagcagttc agcatgagta
     5161 cccttacctg ccagagtacc gttatcaagg acaaggatca ggtctgcctg ctgaatgctg
     5221 gaggaacgct gggataccag aaatgtagtt actttccagt caagtctgtt gagagactta
     5281 cgcagtgctg catcagtggc aaagtccagg gcactggcac tgtcatccag gatcaggatt
     5341 tcaggttttt ttaccagggc acgggcaatg gtaagtcttt gtttctggcc gccggaaagg
     5401 tttttaccgt tctgttccag cataaaatca agctgtcccg gtttaccctc tactacctct
     5461 tttccctgtg ctgtggtaag tgcctgccac agatcctcgt cagaggcatc ttcccggccc
     5521 catttcagat tgtcccggat agagcctttg aaaagagctg ccttctgtgg aacaacgccg
     5581 attctggagc ggagatcact tctggtgtaa ttttcaatat tctgaccatc cagcagaaca
     5641 gttcctttgc tggcatcata gaatctggaa atcagattta ccagagtggt ctttccgctt
     5701 cctgtaccac cgataatacc tacggtctgt ccctttttta cagaaaaact gatatgggaa
     5761 agactggggg caccggcttt gctgtactca aaggttacgt cattgaatac gatggcattt
     5821 tcagaaagtg atgcatcagc agttgctgtt gcaaggtcct tcgatatctg agcagaatat
     5881 gtggaggaag aggggtaatc catagtagat ttcactttca ggatatctgc cacacgtcct
     5941 gcgcaggctg cagatttgtt cagggtgatg atcagggagg caagcttgat cagttccacg
     6001 atcatctgag ccatatagtt ataaagggca acaacctgtc cctgctgcat accgccaaga
     6061 tttacttcta ctcctgcttt ctggatcaga ataacagtag caatattgat cagtacgtaa
     6121 gtgaccggat ttaacaaagc ggaaagcttt cctacaaaga gatttaactt tgtcagctcc
     6181 tgattgcggg tatcaaattc tgcaactgcc tctttttcgc ggcagaatgc acggataacg
     6241 cggacgcctg taaggttttc tctggtcagt ccggttactg tgtccagttt tccctgtact
     6301 tttttaaaca gaggaatact gagaaacata atgacaaaga caaccagaaa cagaaacggg
     6361 atcgcaacag caaaaaccag ggcacattta aagtcaatgg taaatgccat gaccatggac
     6421 ccaagtacga taaacggact tcgaagaaga agacgaagtc ccatatttaa tccgttctga
     6481 atctgattga catcatcggt gagtcttgtg ataagagtat ctgttcccag tgtatccaac
     6541 tctgtatagg acagatgctg tacatggtca taaactgcct gtcttaattc tgtggcaaag
     6601 cccacgctgg ctttagcggc aaagaactga gctgtgatgg tactggcaag accaagagcc
     6661 gccattagta taagaataga aaatctctgg acaatgtatc cgttgtcgtg gtttgcaata
     6721 cctacatcta tgatctgtgc aatgacgata ggtacgatca ggtcaaatac aacctccaga
     6781 aatttaaaaa atggcgcaag gatgctttct tttttgtagt tttttaaata aaccgtcaat
     6841 gaacgcattt taaaaattcc ttcctttcgt aaaaatcttt cctatattat tccttccttt
     6901 ttttgaaaaa taatacattc aaaagtgtat catttaagac ttttttgtca agaagaatgt
     6961 gcaaaaacag atgaactttg gagaaaattc agcttgactt caaaaaaaga tattactaaa
     7021 atattccgta gcgctatttg tacgctggca actgataaat tattattacc ataatgagga
     7081 agagacagac tatggagatt attgagacat ttggtcatta tgtggaaaat ctgacggata
     7141 aaaagcctca gtcagcccga cggctgttaa aaaccggctg ggaggcgcag aatctgaagt
     7201 tccgttacat gcaggacaag agactgatgc ctgcagacag gcatcttgca aatctgatga
     7261 tggataccat gctgcggccc cttcagaaac cggaagattc tgttattgta agtattttta
     7321 caccctgcga aatgatgcag gaggtgggat tacatcccta taatgtagag ggattttcct
     7381 gctatctttc tgcaagcaaa gcagagagga cgtttctgca gcaggcagag aatcagggaa
     7441 ttgcagagac actgtgcagt tatcacaaga catttcttgg tgcagcgcag aaaggacttc
     7501 tgccaaagcc taaatgtatt gtttatacca acctgacctg cgatgctaac ctgctcactt
     7561 tccgtaccct ggcagatttt taccaggtac ctgtatttgc cattgatgta ccatggaatc
     7621 agaccacaga gaatgtacag tatgtggcag atcagttaaa ggatttaaaa atatttctgg
     7681 aaaaaaatac aggaaaaaca atctctgagg acagattaaa ggaacgtctt gcctgcagta
     7741 agcggactct ggagaattac aaaaaatatc agcagatgcg tgcagacaga tatgtgccct
     7801 ctgatctggt cacacccttg tatgcaggaa tgacaaacaa tatccttctg ggaacagcag
     7861 aagaagagaa gtatacacag atgcttcttg aagatattaa gaaagcaccg gcagcgaaag
     7921 ggaaacacat ttactggatg cataccattc cattctggtc ggatgcagtg cgccaggagc
     7981 tttgcttcag tgagaaagcc cagatcgtag gatgtgaact tgcagaaacc tgtgagccgg
     8041 attttgatcc tgagaacccc tttgaagcaa tggcagaaag aatggtatat cattcactga
     8101 acggaagtgc ccttagaagg attgaagccg gtatccgcca tgcgaaacag gcaggagcag
     8161 acggtgctgt gtggtttgga cattggggat gtaaacatac gcttggtgcg gcacagcttg
     8221 caaagaagaa gttcgaggaa gccggtctgc cccttttaat cctggacggt gacgggtgtg
     8281 atcgaagcca tggaggagaa ggacagactt ccaccaggct gggagctttt ctggaaatgc
     8341 tgggaggtgc tgagaatgaa taaaacttac tatgtctgta aatatacccc aattgaactt
     8401 ctggaatctc ttggcgggga atgtgagaac tttaatcata tgccggaggg atttgacctg
     8461 gccgatcagg tttcacatcc caatatctgc ggttttggaa aaacacttct ggaaggagtc
     8521 atggagggga aaatcaagga acttgtcctg gtgagctgct gtgatactat ccggagtgtc
     8581 tatgacattc tgcttgaaag cggcaagctg gattttctct atattttgga tgtgcttcac
     8641 tgtgacagtg cctgtagcag agagcgtatg gctgtacagt taaaagggct ggcgaaggct
     8701 tatgcacagt acaaaggcac agagtttgat gccggaaaat tccgggctgc tttccatgca
     8761 caggagaaaa tcacaaagtc ccatattgca gtgcttggcg ccagaatggg gcaggaatta
     8821 tttgaaatga ccagcaaggc tatgcctctt cctgtagaga atgatacctg cgtgcataac
     8881 cgttctgtgg gaaatatact tccaccggag ggtgcttctt ttgatgagct gatggactgg
     8941 tatgcaggtg agattctggg gcagattcca tgtatgcgta tgatggaccc gacaggtcgt
     9001 aagaagcttt ataatgatcc gtctgttgcg gggattattt atcatacagt gaagttttgt
     9061 gatttttaca gcttcgaata tgctgagatc aagaaccata cagatgtacc tcttttaaaa
     9121 attgaatcag attatactat tcagagcagc ggtcagcttc ttaccagact ggaagctttt
     9181 gcagagagca ttcagcctga aacactggag cagaccatag atggagacac aaaaggagag
     9241 agaaaaatgg gaaaaggtta tttcgcaggg attgacagtg gttccaccag tacagatgtg
     9301 gtgattttaa ataaagatca tgagattgtg accagcatta tcctgcctac aggagcagga
     9361 gctgctatcg gagcagaccg tgcccttgca gaagcattga aggaggccgg attgcagaga
     9421 gaagatattg atgcgctggt tactaccgga tacggacgta cagctattaa aaatggtgat
     9481 aagagtatca cagagatcac ctgtcatgca aggggtgcgc atttcctgaa tccggaagtc
     9541 cgtactgtta ttgatattgg cggacaggac agcaaggtga tccgactgga tgagaacggt
     9601 gcagttgcaa actttgttat gaatgacaaa tgtgcggcag gaaccggacg atttctggaa
     9661 atgatggcac gtaccatgga aatgaatcta gatcagatga gcgaatgtgg gctggaattc
     9721 aaagaagata ttacaatttc cagtatgtgt acagtatttg cagaatcaga agttgtatca
     9781 ctgatcgccc agaataaggc aacagatgat attgtccatg gcctgaataa ggcggttgcc
     9841 gtaaagactg ccgcccttac cagacgtgtg ggcggtgagg agaaatatat gatgaccggt
     9901 ggtgtttcta agaataaggg tctggtaaag acactggaag agaagcttgg aacaaagctg
     9961 gtgatcagtg acaaggctca gctttgcggt gcacttggcg cagcactgtt tgcggctgat
    10021 atggctgatg tgtaaatttt tagttactgt tcactac
//
