LOCUS       c00063_gnlPro..        15642 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PIJKPNMN_63.
ACCESSION   c00063_gnlPro..
VERSION     c00063_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 03:05:30
            Original ID  :: gnl|Prokka|PIJKPNMN_63
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15642
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15642
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2507:5642]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2508..5642
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..15642
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15642
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(94..330)
                     /locus_tag="ctg63_1"
                     /transl_table=11
                     /translation="MKIKNITDIDGFFKVIDSCQGKVELITGEGDRLNLKSKLCQYVSL
                     TSILKTDVEIPELELVAYEPEDTEKIIKFLMKG"
     CDS             complement(402..2402)
                     /locus_tag="ctg63_2"
                     /transl_table=11
                     /translation="MKHAKDKARFGVKAKLMSFILPVVAIAFLILSMVAFFVSRASIRE
                     KTESLMDAEGTASVNQIAGWQSDNLTTLDTALDSMVYLKMDDEEILNYEAQFLGTYEDF
                     PNGVYLSYDDGKVLDASGWEPEGKATETTWYQEGLGHDKFAFGDPYVDALTGSYIVTAS
                     RYVEKLNGKGAVAAADVSLDILSEVVSGMEVAGDGDAFIMDAASGIVLAHKDADLVGKK
                     AEECGDTLYEEIFTDISAGNVTKNIYTSNQGTYMVNIQNINGTNWYLVARGLEKNIFAD
                     IIRLQMILTVVGVATLLVIGIVMVAVIRRITNPIQKLTGTIVAVTEGDFTTDIEVKGSD
                     EVTVMAGNMKEFLAGMRQILSSIITISNKIDDQAKASNQVSSDLHDSAVGQADAMGQMR
                     TTLEELVKSINVIAENATTLAQVVADTNEAGSEALQNIENTISEASEGKNGMTSVTKSM
                     DDVKGSMQVLGKSIGDVGAAAVKINEITGTIRGIADETNLLALNASIEAARAGEAGKGF
                     AVVATQIKNLAENSGEAADEISSLIDSVTSLIEETVNQSGRSTEQINESAAAVFAAAEQ
                     FNNIYESIEQTNRIVQGMIEKVHEVNDVASNMAAITEEQSASAEEIEATAVSIQELADI
                     VSENSADVQKDSKEMESTAETLKKHISRFTI"
     CDS             complement(2508..3269)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 74.6;
                     E-value: 3.1e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg63_3"
                     /sec_met_domain="Radical_SAM (E-value: 1.4e-33, bitscore:
                     107.0, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKIHSMESFGTVDGPGVRFVVFFEGCPMRCLYCHNPDTWHLEDG
                     QEMSAEEILSRMERNRSFYRTGGITATGGEPMLQIDFLTELFAGAKERGIHTCLDTSGI
                     MFPGCGGTSEEERERLKKVERLLSVTDLVMLDIKHMDAEEHRKLTGQDNEKILAFARYL
                     DEKQIPVWIRHVVVPGITFQREELEALGRFLATLSNVEKLEVLPYHSMGKVKYDNLGID
                     YALKDTPQLTKAEAKSAESIILEAMRQARNV"
     CDS             complement(3414..5642)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg63_4"
                     /sec_met_domain="Gly_radical (E-value: 4.6e-46, bitscore:
                     146.2, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 1.1e-281, bitscore:
                     925.8, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQNEWRGFQRGSWEEEINVRDFIQKNYTPYDGDDSFLEGPTQDTT
                     DLWNEVLELSKQEREAGGVLDMDTKIISTITSHGPGYLDKSKEKIVGFQTDKPFKRSLQ
                     PYGGIRMAVKACEDNGYHVDPEVVEYFTTHRKTHNAGVFDAYTPEMRACRSAHIITGLP
                     DAYGRGRIIGDYRRPALYGVDRLIEDKEEQLATTRTIMYSDVIREREELSEQIRALKML
                     KELAKIYGCDISKPANNVLEATQAVYFSYLAAVKEQNGAAMSLGRTSTFLDIYAERDLK
                     EGTFTEKEIQEIIDQFVMKLRCVKFARTPEYNSIFAGDPTWVTESIGGIGVDGRHMVTK
                     MSYRYLNTLNNIGAAPEPNMTVLWSVQLPENFKRFCAQTSIRHSAIQYENDDIMRVVHG
                     DDYGIACCVSSMRIGKEMQFFGARANLAKCLLYAINGGVDEISGKQVGPKYRPITSEYL
                     DYDEVWDKYKDMMKWLAGVYVNALNIIHYMHDKYCYEKLEMALHDKKVRRWFATGIAGF
                     SVVADSLSAIKYAKVKPIRDENGITVDFEVEGDFPKYGNDDDRVDDIAKEVLHTFIGYV
                     KGNHTYRGGIPTTSILTITSNVSYGKNTGATPDGRKKGVAFAPGANPMHGRDTNGAVAS
                     LASVAKMPFMDSQDGISNTFTIVPDALGKDETGEEQNLVALLDAYVEKGGHHLNVNVLN
                     RETLLDAQKHPEQYPQLTIRVSGYAVNFIKLTKEQQDEVIARTFHERM"
     CDS             complement(6046..6963)
                     /locus_tag="ctg63_5"
                     /transl_table=11
                     /translation="MESYTLEEKVLRKVMRNIPMGLIVSKEGFRRKIYYVNDTACEIMG
                     YTREEYIRKMQDGWTDLMDVDLREVIREHNEQIRSGTPFEVLSRPQTKNGGYKWILSRV
                     NVQMQEGPLCYVSFMDVTDRMEREELCRQENEVLREQAMQDSFTKLLNRGALEKHVCEA
                     LQERGGDEEDAFILLDVDNFKQINDIYGHGVGDMILMRMAGILNEVFGDHSCIGRMGGD
                     EFAVFLRDIGDRREIEEKIQKLLTEVRAEKERMHLSKEPTASVGVAFVPESGSTFVDVY
                     RAADQALYHVKNSTKNGMAFYDFV"
     CDS             complement(7150..8097)
                     /locus_tag="ctg63_6"
                     /transl_table=11
                     /translation="LEQIKYYMAPMEGVTGYVYRNAYAKYYGGIERYFTPFVANKKLGH
                     REKNDVCPEHNAGMAVVPQILTNRAEDFLAIAEILREYGYDTVNLNLGCPSGTVAARGR
                     GAGFLAMPDELDHFLEEIFEKCPLRISIKTRIGKENPAEWERLLAIYEKYPLEELIVHP
                     RVQTDFYKNRVNLEAFALAEKNSRHSLCYNGDIVDAASAAHIREGFPSVDKFMIGRGLI
                     KRPWLLEELSGGRQEKQERKERFLQFHNAILEGYRQQMSGDKNTLFKMKELWAYWGENF
                     TDADQRLKKIRKCERVAEYECLVDALFREKELCV"
     CDS             8251..9108
                     /locus_tag="ctg63_7"
                     /transl_table=11
                     /translation="MKSTFSDSPGNHNRWFRPHFSHFCATRLGRFINESRYGGILYLAL
                     WLVVLGLVFTLFQTIFLSIAYTGRLTPDDYEVLHVEQTEYDQSIGAYDSGIIRRFSDYL
                     VTVQYEVDGTRYTADLSLGQAFFTGNRVARAGADGSSVLGTIFYKSSDPKRLKYIPARR
                     HILPFSTGKYVCREDTDDFAAQVCALLQQEDYGSLAALSYNGRDIPVTAEDTEEYFHDD
                     LVYFRKNVGDLSLLEGTTVYHDTPWATAVTIRYYSKEAQETYSDYLPITVKDGHYRLDL
                     RWKY"
     CDS             complement(9134..9685)
                     /locus_tag="ctg63_8"
                     /transl_table=11
                     /translation="MELLDIVDEKGNPTGETVPREVAHREGIRHRTAHVWIFRRRGGVV
                     QILLQKRSDNKDSDPGCYDISSAGHIPAGSDYIPSAVRELKEELGVDMNGDELIYCGQR
                     RFRFEREFHGSMFRDNQVSNVYALWLDREEEAFVLQEEEVSEVRWMDFADCVSAVRENR
                     ISHCIYMEELELLKNALHLH"
     CDS             complement(10466..12262)
                     /locus_tag="ctg63_9"
                     /transl_table=11
                     /translation="MKWKKLVTLGCVVVMTVSSVTACGSNTTENQTVEATEQSEENQSD
                     SVIVQVTAVEGDQITADVGTLTTASADASGNGAPGGEAPSGEAPGGDDSGNGASGEAPS
                     GEAPGGEAPSGDNSGNGALGEAPSGDAPGGQMPGGSSFEASGESITFTLTDDTAITLEY
                     LQGSDEGNADDIAVGSVLEVVLDEDNQAVSVTVRNLNAGGGFGGSGEVTNGTSANTITE
                     DTEVDSETYTSTGDDENALRVDGATVTLKDITIEKTAGSSSNTEDGDFYGLNAGLLVLN
                     GATATITGATVNTSVTNGNGVFSYGEGTVVNISDSTIRTTENNSGGIQTTGGGTMNAAN
                     LDVETQGNSAAAIRSDRGGGTVKVDGGSYVTNGTGSPAIYCTADISVSDATLTANASEG
                     VVVEGKNSVALTDCDVTGNMSNTYNGDSDENIHCIMIYQSMSGDADVGEAAFSAEGGSI
                     TAKTGDMFYITNTDCEITLKDVAFTLANDVFLRVEGNSSSRGWGTEGANGGDVTLTADS
                     QEFTGNILVDEISSLALTMKNGTSYEGAINPDGAGGTVDVTLDDNSTWTLTGDSYITSF
                     DGDTSNITANGYHLYVNGEQVL"
     CDS             complement(12388..12774)
                     /locus_tag="ctg63_10"
                     /transl_table=11
                     /translation="MTKKARLKKLLLYMMLLGMAGLLYGIFVSYTGLAIPCLFRKVTGL
                     LCPGCGVTGMCVALLHLDWRGAFSCHPVLFVLLLPLTAVFICGAAGYVQNGRFRFARWQ
                     NLILYVSVAALVIFGVVRNLVRFL"
     CDS             complement(12792..13133)
                     /locus_tag="ctg63_11"
                     /transl_table=11
                     /translation="MIERRNIAVCIVLTLVTCGIYGIYWIVCLTNDVNTVSGDVNGTSG
                     GMVVLLTIVTCGIYGIYWAYKQGEKLDFTKNNRGIPSSNSGVLYLILQIFGFGIIAYAL
                     MQNELNKLA"
     CDS             complement(13215..13655)
                     /locus_tag="ctg63_12"
                     /transl_table=11
                     /translation="MKDKYDALKLENQLCFPLYACSKEIVRRYKPYLDEIDLTYTQYIA
                     MMVLWEHGRINVKDMGALLYLDSGTLTPVLKKLEQKGYLTRERDHADERVLNVTITEAG
                     EQLKEQAVDIPRKMGGCIGLSGEDARELYRILHKVLALMEQE"
     CDS             complement(13671..14057)
                     /locus_tag="ctg63_13"
                     /transl_table=11
                     /translation="MGFEILDFPCDQFEHQAPGTNEEIVAFCDVNFGITFTHYGKIDVN
                     GEHALPLYQYLKSQKGFAGFDEEHPLATIVESMLERTHPDYKETPDIKWNFTKFLIDRD
                     GNVVERFEPTADMDVVREKIENYL"
     CDS             complement(14088..14405)
                     /locus_tag="ctg63_14"
                     /transl_table=11
                     /translation="MVKKIQNNNMDEALQAKAAVVDFSAVWCGPCQMLAPVLEELSGDL
                     DGKVAFYNADTDENTQLAIANGITNIPALLFLKDGKVAGKNVGFMPKPELEAWVKGCME
                     Q"
     CDS             complement(14417..15283)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg63_15"
                     /sec_met_domain="Pyr_redox_2 (E-value: 7e-24, bitscore:
                     74.9, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERVDIAIIGTGPAGVSAAITAKVRNKSVLLIGSRELSEKMSKAH
                     QILNYPGLPEVSGADLVAGYKKQLAGLGIEVTEKRVNAVYAMGDYFGIQASGEILEAST
                     VILAAGSVMGKPFPGENKLLGSGVSYCATCDAQFFRGKEVAVIGYGREAEQEADYLAEI
                     VGKVHYFPMGKEEPQLSDAVEVVHERPKAITGTQTVSALETDAGTHPVDGVFILRDAIA
                     PSQLVPGLATEENHVKVNLQMETNLPGLFACGDITGKPYQYIKAAGQGNVAALSAAEYL
                     DKKKREI"
     CDS             complement(15315..15470)
                     /locus_tag="ctg63_16"
                     /transl_table=11
                     /translation="MLRKIDKNYKENPDIKWNFTKFLVDRQGTVVVRFEPTGDMNELER
                     QILALL"
     CDS             complement(15470..15568)
                     /locus_tag="ctg63_17"
                     /transl_table=11
                     /translation="MGIYDYSVERPDGTMQPLSTYEEKWRKRRRWE"
ORIGIN
        1 gcctaggcgt gttcgggact ttcacccgtt agagcgcgcc catggcgcgc aaaccaaaaa
       61 agaaccgcca acctgtgttg acggttcttt ctctcagccc ttcatcagaa acttaataat
      121 tttctctgta tcttccggct cgtaagcgac aagctcaagc tccggaatct ccacatccgt
      181 ctttaaaata ctggtaagtg atacatactg gcaaagcttt gacttgaggt tcagtctgtc
      241 cccctcaccg gtaatgagtt ccacttttcc ctggcaggag tctattacct tgaaaaatcc
      301 gtcgatatcc gtgatgttct tgatcttcat aatgcatgct cctttcttat tatctgagtc
      361 tctatctaca ctataatacg aaagtacctc ttctgcaagt tctaaatcgt aaacctggaa
      421 atatgtttct tcaacgtctc ggccgtgctt tccatctcct tcgagtcttt ctgcacatct
      481 gcactgttct cggaaacaat gtccgccagt tcctgaatgc tgaccgccgt tgcctcaatc
      541 tcctccgccg atgcagactg ttcttccgtg atagccgcca tattggacgc gacatcgttt
      601 acctcatgca ccttctctat cattccctgc acgatccggt tggtctgttc aatactctcg
      661 tagatattgt tgaactgctc tgccgccgca aataccgccg ccgcactctc attgatctgc
      721 tctgtgcttc gtccgctctg gttcacggtc tcctcaatca gactggtcac cgaatcgatc
      781 aggcttgaga tctcatccgc tgcctccccg gagttttccg caagattttt gatctgtgtc
      841 gcaaccaccg caaagccttt tcctgcttcc cccgcgcgcg ccgcctcgat acttgcgttc
      901 agtgcgagca ggttcgtctc gtccgcgatc ccgcggatcg ttccggtaat ctcgttgatc
      961 ttgacagcag cggctcccac atcgccgatc gattttccga gtacctgcat gctgcccttg
     1021 acatcatcca tggattttgt cacggaagtc atgccgttct tgccctcgga cgcctccgaa
     1081 atcgtattct ctatattctg cagagcctcg ctgcccgcct cgttcgtgtc ggcgaccacc
     1141 tgcgcaagtg tggttgcatt ttccgcaatc acattgatgg atttcaccag ttcctcgagc
     1201 gtcgtccgca tctgtcccat cgcgtccgcc tgccccaccg ccgagtcgtg cagatcactc
     1261 gacacctggt tgctcgcttt tgcctgatcg tcgatcttat tggaaattgt gataatggag
     1321 cttagaatct gacgcattcc cgccagaaat tccttcatgt tacccgccat cacggtaact
     1381 tcgtcgctgc ccttgacctc gatgtccgtc gtaaaatcgc cctctgtgac ggcaacaatc
     1441 gttccggtca gcttctggat cgggttcgtg attctgcgga tcaccgcaac catgacaatt
     1501 ccgatgacaa gcagcgttgc cacgccgacc accgtcaaaa tcatctgcag tcttatgata
     1561 tccgcaaaaa tattcttctc cagaccgcgg gctaccagat accagtttgt cccgtttata
     1621 ttctgaatat tcaccatata cgttccctga ttggacgtat aaatattttt cgttacattt
     1681 cccgcggaaa tgtccgtaaa aatctcctcg tagagcgtat ctccgcactc ctctgctttc
     1741 tttcccacaa gatccgcatc tttgtgtgcg agcacgattc cgctcgccgc atccatgata
     1801 aatgcgtctc catctccggc cacttccatg ccggacacaa cctcggagag aatatccagg
     1861 ctgacatccg ccgccgcaac tgcgcccttg ccgtttaact tctccacata gcggcttgcc
     1921 gttacaatgt agctgcccgt cagcgcatcc acataaggat cgccgaatgc gaacttatca
     1981 tggccaaggc cttcctgata ccaggtcgtc tccgtcgctt ttccttccgg ttcccagccg
     2041 gaagcgtcca gcaccttgcc atcatcgtaa gacagataca caccgttcgg gaaatcctca
     2101 taggttccca aaaactgtgc ctcatagttt aaaatctctt catcgtccat cttgagatag
     2161 accatgctgt caagcgccgt gtccagcgtg gtgaggttat cgctctgcca gcccgcaatc
     2221 tgattcacac tcgccgtgcc ctccgcatcc atcaggctct ccgtcttctc gcggatgctc
     2281 gccctggaaa caaaaaaggc aaccatactc aatataagaa atgcaattgc aaccaccggt
     2341 aaaataaatg acatcagttt tgcctttaca ccaaaccgcg ctttatcttt tgcgtgcttc
     2401 atgagtacct ccttcatctt acgcattttt attcattttg tgttctcata atagcaccgc
     2461 tgctcctgta tttccagtat ctttttttgt acaatccatt ttaccggtca gacgtttctc
     2521 gcctgacgca ttgcctccag aatgatgctc tccgcactct tcgcctccgc cttggtgagc
     2581 tgtggcgtat cttttaatgc gtaatctatc ccgagattgt catacttcac ttttcccatg
     2641 gagtgatacg gaagtacctc cagcttttcc acatttgaaa gtgttgcaag aaaccggccc
     2701 agagcctcca gttcttccct ctgaaatgta atccccggaa cgaccacatg ccggatccag
     2761 accggtatct gtttttcatc cagatacctt gcaaacgcaa gtatcttctc attgtcctgt
     2821 ccggtcagct tcctgtgctc ctccgcatcc atgtgtttga tgtcaagcat cacaagatcc
     2881 gtcacagaaa gcagccgttc caccttcttt aagcgttccc gctcctcctc tgatgtgccg
     2941 ccgcaccccg gaaacataat gcccgaggtg tccagacagg tatgaattcc acgttccttt
     3001 gccccggcaa acagttccgt caaaaaatca atctggagca tcggctctcc gccggtcgca
     3061 gtgattccgc cggtccggta aaacgaccgg ttgcgctcca tgcgtgacag aatctcttcc
     3121 gcgctcatct cctgcccatc ctccagatgc caggtgtcgg gattatggca gtacaggcag
     3181 cgcatgggac atccctcaaa gaacaccaca aaacggactc ccggtccatc cacagttcca
     3241 aagctttcca tcgaatgaat ttttcccata aagtcctcct ttttaatccc atccatctga
     3301 taatcataat acaatcgcgc gagccggcgt atcccggtgt ccctgccgca aaagcagcag
     3361 ggcaccggtt ccggttcgcg cgatttatcc tgtctgtatc acttccacat gaactacatg
     3421 cgctcgtgga aggttcttgc aatgacttcg tcctgctgct ctttggtcag cttgataaag
     3481 tttaccgcat atccggaaac acggattgtg agctgcggat actgctccgg gtgtttctgt
     3541 gcatccaaaa gcgtctcgcg gttcaatacg ttgacgttca agtgatgtcc gcccttctcg
     3601 acgtaagcat ccagcagcgc cacaaggttc tgctcctcgc ccgtctcatc cttgccgagt
     3661 gcatccggca cgatggtaaa cgtgttggag ataccatcct gggaatccat aaacggcatt
     3721 ttcgctaccg acgcgagaga tgctaccgca ccgttcgtgt cgcgtccgtg catcgggttt
     3781 gcgcccggtg caaaggcaac acccttcttt ctgccatccg gtgtcgcacc tgtgttcttg
     3841 ccgtaggata cgttggatgt gatcgtgagg atcgatgtcg tcgggattcc gccgcggtag
     3901 gtgtggttgc ccttgacata gccgatgaat gtgtgaagca cttcctttgc aatgtcgtcg
     3961 acgcggtcgt catcatttcc gtatttcggg aagtcaccct ccacctcgaa gtctacagtg
     4021 attccgttct catcgcggat cggctttacc tttgcgtact tgatggcaga cagggaatcc
     4081 gccacaacgg aaaaaccagc gattccggtc gcgaaccagc ggcgcacctt cttgtcatga
     4141 agcgccatct ccagcttctc gtagcagtat ttgtcatgca tataatgaat gatgtttaag
     4201 gcattgacat aaacacctgc cagccacttc atcatatcct tatacttatc ccacacctca
     4261 tcgtaatcca ggtactcgga agtgatcggg cggtacttcg gtccgacctg cttgccgctg
     4321 atctcatcta caccgccgtt gatcgcgtac agaaggcact ttgcaaggtt ggcgcgggcg
     4381 ccgaagaact gcatctcctt accgatgcgc atggaggata cacagcatgc aattccgtaa
     4441 tcatccccgt gtaccacacg catgatgtca tcattctcgt actggatcgc agagtgcctg
     4501 atggatgtct gtgcgcagaa acgcttaaag ttctctggaa gctgtaccga ccagagcacg
     4561 gtcatattcg gctccggcgc tgctccgatg ttgttgagtg tatttaagta gcggtaggac
     4621 atcttcgtca ccatatgtct gccgtccaca ccgattccgc cgatcgactc cgtcacccag
     4681 gtcggatccc cagcgaagat ggagttgtac tccggcgtac gtgcaaactt cacgcagcgc
     4741 agcttcatga caaactggtc gatgatctcc tggatctcct tctctgtgaa cgttccttcc
     4801 ttgagatcgc gctccgcata gatgtcgagg aatgtggagg tacgtccaag gctcattgcc
     4861 gcaccgttct gctccttgac tgctgcaagg taggaaaaat ataccgcctg cgtcgcttcc
     4921 agcacgttgt tcgccggctt ggaaatgtca cagccgtaaa tctttgcaag ctctttcagc
     4981 atcttgagtg cgcggatctg ctcggaaagc tcctcacgct cacggatgac atccgagtac
     5041 atgatcgtac gggtcgttgc gagttgttct tccttgtcct cgatcaggcg atccacaccg
     5101 tagagtgccg gtcttctgta atcgccgata atacgtccgc ggccatatgc atccggaagt
     5161 cccgtgatga tgtgtgccga acggcatgcg cgcatctccg gtgtgtaggc atcaaataca
     5221 ccggcgttgt gtgtctttct gtgcgtggta aaatattcca ccacttccgg atctacatgg
     5281 tagccgttat cctcgcaggc tttcactgcc atgcggattc cgccgtacgg ctgcagggaa
     5341 cgcttgaacg gcttatctgt ctgaaagccg acaatcttct ccttgctctt gtccagatag
     5401 cccggtccgt gggatgtgat cgtggagata atcttggtat ccatatcgag gacaccgcct
     5461 gcctcacgct cctgcttcga cagttctaac acttcgttcc ataaatctgt cgtatcctgc
     5521 gtcggtcctt ccagaaagct gtcgtccccg tcgtaaggcg tatagttttt ctggataaaa
     5581 tctctgacat tgatctcttc ctcccagctt ccccgctgaa agcctctcca ttcattctgc
     5641 atgattcttc ctcctgctta ctttgtaatg tgattatgtt ccctgcccgc aggcagcatt
     5701 gccaaaacat gatattggtt agttgtagct aacctttata aatatagcat agcgtgcttt
     5761 tccctgtcaa tatcaagttt tgttgccagg cgtgtttgtc ttgtcttact ctcagtgggt
     5821 attttatgct ttttgagcca aagcatcttt tgtcttagag atgggaatcc cgggtgcttt
     5881 ttcgataaaa agcaccctga ttcaaaacaa gccgactgcc cgggtacatt cgcccagacg
     5941 gtcggcatta gatacgttat actccatgtg gttcttccac ttgttccgtc agtcatataa
     6001 catcttaatc ttacagtata tgatgatttt tttcaatagg aaaaattata caaaatcata
     6061 gaacgccatt ccattcttcg tcgagttctt cacgtgatac agcgcctgat ccgccgcccg
     6121 gtacacatcc acaaacgtgc ttcccgattc cggcacaaat gcaacgccga cactggctgt
     6181 cggttccttg ctcaggtgca tccgttcttt ttcggcgcgt acctccgtaa gaagcttttg
     6241 aatcttctct tcaatctctc tccggtcgcc gatgtctctg aggaaaacag caaattcatc
     6301 gccgcccatc ctgccgatac aggaatgatc tccaaacact tcgtttaaga ttcccgccat
     6361 ccgcatcaga atcatatccc cgactccgtg accgtaaatg tcattgatct gcttaaaatt
     6421 atcgacatcc agaagaatga atgcatcctc ctcatcgccg cctctctcct gaagcgcctc
     6481 gcagacatgc ttctccagcg cgccgcggtt tagaagcttc gtaaaggagt cctgcatcgc
     6541 ctgctccctg agcacctcgt tctcctgccg gcacagttcc tcccgctcca tccggtcggt
     6601 aacatccata aagctgacat agcagagcgg tccctcctgc atctgcacat tcaccctgct
     6661 taatatccac ttgtaaccgc cgttcttcgt ctgcggtctt gagagcacct caaacggcgt
     6721 cccggaacga atctgttcat tgtgctcgcg gatgacctcc cgcagatcga catccatcag
     6781 atccgtccat ccgtcctgca tctttctgat atactcttcc cgcgtgtatc ccataatctc
     6841 acacgccgtg tcgttgacat agtaaatctt gcgccgaaat ccctctttgc tcacaatcag
     6901 tcccatcgga atattccgca tgaccttgcg aagcactttc tcctctaacg tatagctttc
     6961 catataccct ctttaaaacc tcttccccaa ttcccctatc gttctcatga agcatactac
     7021 ggagtacagt ataatacttt ttacagcaaa taaaaagtcc ctttcgtctt tttatataaa
     7081 tgttacagat tggaaagctt cttttttgtt atatcacaca aatctattgc cgcatacccc
     7141 actcttttcc tacacgcaca gctctttttc acgaaacagc gcgtccacca gacattcata
     7201 ctcagcaacc cgctcacatt ttcggatttt ttttagacgc tggtccgcat ccgtaaagtt
     7261 ttctccccag tacgcccaca gttccttcat cttaaataag gtatttttgt ccccggacat
     7321 ctgctgccgg tatccctcca ggatcgcatt gtgaaactgg agaaaacgct cttttcgctc
     7381 ctgcttttcc tgtctgccgc cggaaagttc ctccagaagc caggggcgct ttatcagtcc
     7441 cctgccgatc atgaacttat ccaccgacgg aaaaccctcc cggatgtgtg ccgcagacgc
     7501 tgcgtccaca atgtcgccat tgtagcagag cgaatgtctg ctattttttt ctgccagtgc
     7561 aaatgcctcc agattgaccc ggttcttata aaaatcggtc tgcaccctcg ggtgtacgat
     7621 cagttcttct aacggatatt tttcatatat ggcaagcagc cgctcccatt ctgcagggtt
     7681 ctcttttccg atccgcgtct tgatggagat ccggagcgga catttttcaa aaatctcttc
     7741 cagaaaatga tccagctcgt ccggcatcgc aaggaatccg gcgccgcgcc ctcttgccgc
     7801 cactgtgccc gacgggcagc cgaggttcag gttgaccgta tcgtacccat actcccgcag
     7861 aatctctgcg atcgccagga aatcttctgc gcggttcgta agtatctgcg gaacgacagc
     7921 cattcccgca ttgtgttccg gacagacgtc atttttctcc cggtgtccaa gctttttatt
     7981 cgccacaaac ggcgtaaaat agcgttcgat cccgccgtaa tattttgcgt atgcattccg
     8041 gtagacatat ccggtgacac cttccatggg tgccatataa tactttatct gctccaactg
     8101 tcttctccct ctgtcagaaa tctgtccctt atcttaatac agctcttccc gcctgtcaaa
     8161 tagtggaaaa ttccgccttt ttttgctata ctgctattga tacagctttc acaaacccgt
     8221 ttatagctca ttatattcag gagaatttct atgaagtcga cattttcaga cagcccgggc
     8281 aatcacaacc gatggttccg cccccatttt tcgcattttt gtgcgacccg tctcgggcgt
     8341 ttcatcaacg aatccagata tggcggtatt ctctatctcg ccctgtggct ggttgtactc
     8401 gggctcgttt ttactctttt tcagaccatc tttttaagta tcgcctatac cggccggctc
     8461 acgccggatg attacgaagt ccttcatgtg gagcagaccg aatatgacca gagtatcggt
     8521 gcctacgatt ccggtatcat cagacgtttt tccgattacc tggtaaccgt gcaatatgag
     8581 gttgatggaa cgcgctatac tgcagatctt tcactcggtc aggcattttt caccggaaac
     8641 cgcgtggcac gcgccggtgc agacggctcg tctgtacttg gcaccatttt ctataaaagt
     8701 tccgatccaa aacgcctgaa gtacattccg gccagacggc acattctccc attttcaacc
     8761 ggcaaatatg tctgccggga ggataccgat gattttgccg cacaggtctg cgcgctttta
     8821 cagcaggagg attatggctc cctcgccgcg ctttcctata acggcagaga tatccctgta
     8881 accgcggaag acacagaaga atattttcat gatgatctgg tgtatttccg taaaaacgtg
     8941 ggggatcttt cgttgctgga gggaactacc gtatatcacg acaccccctg ggcaaccgca
     9001 gttaccatcc gctattactc caaggaggca caggagacat actctgacta tctgccgatc
     9061 acagtgaagg acggacacta ccggctggat ctccgctgga aatactgagc cgttttccct
     9121 gcctcccctc gaatcaatgc agatgcagtg catttttcag aagttccagt tcttccatgt
     9181 aaatgcagtg ggaaattcgg ttctcccgga cagcagatac gcaatccgcg aagtccatcc
     9241 accggacctc agacacttct tcctcctgca gtacaaaagc ttcctcctcg cggtcaagcc
     9301 agagtgcata cacattgctg acctggttat cgcggaacat gctgccgtgg aattccctct
     9361 caaaccggaa ccggcgttgt ccacaataaa tcagttcatc gccgttcatg tccacaccca
     9421 gttcttcctt caactcccgc accgcggaag gaatataatc actccctgca ggaatatgac
     9481 cggcacttga aatgtcataa cagcccggat ctgaatcctt attgtcgctc cgtttctgca
     9541 aaaggatctg cactacgccg ccgcgtctgc gaaaaatcca cacgtgcgcc gtacggtgcc
     9601 ggattccctc acggtgtgcc acctcccgcg gcactgtctc tcctgtcgga tttccctttt
     9661 cgtccacaat atccagcagt tccatctctg ctcccctcca gtatgattgt attcttttca
     9721 ttcactatag cacacttttg ctgccttttt ccacatatcc gaaattcttc cggagcgtct
     9781 gatataattc cactaaaata cataatctct ctcttgaaaa aaagctgccg cattcagcag
     9841 atcgtcctgt ttgacgagat aagtaatatt atgagaagca taccgttacg atttcgggtg
     9901 gaatgcctag ggaacattct gttcaaaaaa tgcggcattt ctaaccagcc ggtggctgca
     9961 tctgcgatga tccgtgtctt tccaagtttg gagcactccg acggggcatg tccgcactcc
    10021 ggaagacaat ttgtaggact tttgtgtgtg tcccttattg gcaccagaca acagctggca
    10081 taaatgccac ctttatgtcg aacaaaacat aaccgcgcga agccgctgtc tgagtcggca
    10141 tctgccctat tttcaatagc agatgccggc gagttcggtt cgcgcggttt tatattgtct
    10201 gtgaagaggt gccattaggg acaccagaaa gtccgcccat tgtctccggt gtgtcggaca
    10261 tgcacccgtc agtgtccaaa cgtggaagag acacggaatc agatgcagtc atccggctgg
    10321 aagaaataca cacatttttc tccaacgaat gtttcctatg cagttccacc cggaatctgc
    10381 atcatgtgct tcctgtaata ttacttatca tcaactgcca cctgtgatat gtggcagcct
    10441 ctttttcaac tgcctctcta atctgttaca gtacctgctc tccgttcacg tacagatgat
    10501 atccgtttgc cgtgatattg gaggtatcac cgtcaaagct tgtgatatag ctgtcaccgg
    10561 tcagtgtcca ggtggagttg tcatccaggg tcacgtcaac cgtaccgccg gctccgtccg
    10621 gattgatggc gccctcgtag ctggtgccgt tcttcatggt aagtgccagg cttgaaatct
    10681 catccacgag aatattgccc gtaaactcct gtgaatccgc cgtcagtgtc acatctccgc
    10741 cgtttgcgcc ctctgtgccc catccgcggg aggaagagtt gccttccacg cgaaggaata
    10801 catcattggc aagtgtaaat gcgacgtcct tgagtgtaat ctcacaatcc gtattggtga
    10861 tatagaacat atcccctgtc tttgctgtaa tgctgccacc ctctgcagag aatgctgcct
    10921 ctccgacatc agcatcaccg gacatgctct gataaatcat aatgcagtga atattttcat
    10981 ccgagtctcc attataggtg ttgctcatat ttcctgtcac atcacagtct gtcagtgcaa
    11041 cggaattctt gccctctacc acaacgccct cgctggcatt cgctgtcaga gtcgcgtctg
    11101 acacactgat atctgctgta cagtagattg ccgggcttcc cgttccgttt gtcacatagg
    11161 aaccgccgtc caccttgacc gtaccgccgc cccggtcgct tcggattgcg gctgcggaat
    11221 ttccctgtgt ctcgacatcc agatttgcag cgttcatggt accaccaccg gtcgtctgga
    11281 taccgccgga attattttct gtcgtgcgga ttgtggaatc cgaaatattt acaaccgtgc
    11341 cctcgccata gctgaacaca ccgttaccgt ttgtcacgct ggtattgacc gtcgctcccg
    11401 taatcgttgc cgttgcgccg tttagcacca gaagtccggc attcagtccg taaaaatctc
    11461 catcctctgt gttcgatgag gagccggctg tcttctcgat cgtgatatct tttaaggtaa
    11521 cagtcgctcc gtcgacacga agtgcgttct catcatcacc ggtggatgtg taagtctcac
    11581 tatccacctc ggtatcctcg gtaatcgtat ttgcagaagt tccgtttgtc acctcaccgc
    11641 ttccgccaaa tccgccgcct gcatttaagt tgcgcacagt gacagacact gcctggttgt
    11701 cttcgtccag aactacctcc aatacgctgc cgactgcaat gtcatctgca tttccctcgt
    11761 cgcttccctg cagatactct aatgtgatcg ccgtatcgtc tgtcagggta aaggtaatgc
    11821 tctcaccgga agcctcaaaa ctgctgccgc ccggcatctg accacccggt gcgtctccgc
    11881 ttggtgcttc ccccagcgct ccgtttccgc tgttgtctcc gctcggtgct tctccgcccg
    11941 gtgcttctcc acttggcgct tctcccgacg ctccgtttcc actgtcgtct ccgcccggtg
    12001 cttctccgct cggtgcttct ccgcccggtg ctccatttcc ggatgcatct gcgcttgcgg
    12061 ttgtaagtgt tcctacatcc gctgtaatct gatcgccttc aactgctgta acctgcacga
    12121 tcacagaatc gctctggttc tcctcactct gctctgttgc ttctaccgtc tggttctctg
    12181 ttgtattact gccgcatgct gttacggatg ataccgtcat aactacgacg cagcccaatg
    12241 ttactaattt tttccatttc atgatcttca ttcctctctg actctgtcaa tgtctgtttt
    12301 cttttgatag ggttagtata gaaagccaat gtgaagatca tgtgttgacc acgttaaatt
    12361 attctgaatc tatttttttc ctgtttttca caaaaaacgc accagattgc gcaccacacc
    12421 gaagattaca agcgcggcga cgctgacgta aagaatgaga ttctgccagc gggcgaaccg
    12481 gaatcgtcca ttctgcacat atcctgccgc accgcagatg aatactgccg taagcggaag
    12541 cagcagcaca aacagcaccg gatggcagga aaacgctccc ctccagtcaa gatgcaggag
    12601 agccacacac attcccgtca caccgcagcc cggacacaac agtcccgtca ctttccggaa
    12661 cagacaggga atggcgagcc ctgtgtacga cacgaatatt ccgtacagca gtcccgccat
    12721 tccaagtaac atcatatata atagcaattt tttcaaacgt gcttttttcg tcatcctaca
    12781 tttccgatct gttatgccag cttattcagc tcgttctgca tcaatgcata tgcaataatt
    12841 ccaaatccaa aaatctggag aatcagatac aaaacaccgc tgttgcttga cgggattcca
    12901 cggttattct ttgtaaagtc aagcttctct ccctgcttat atgcccagta aatgccgtaa
    12961 attccacagg tcacaatcgt cagcagcacc accataccgc cggatgttcc attcacatca
    13021 ccagaaaccg tatttacgtc attggtcaga catacgatcc agtagatgcc ataaattccg
    13081 caggttacaa gtgtcagtac aatacacacc gcaatatttc ttctctcaat cataacaaac
    13141 tctcctttaa ataagtatga attcattata tcagtttttt gtatattgtc tactgttttc
    13201 ataccgtggc catttcattc ctgctccatc aacgcaagca ccttgtgcag gatgcggtac
    13261 agctccctcg catcctcccc ggacagtccg atacagccgc ccatcttccg cggaatgtcg
    13321 accgcctgct cctttagctg ctctcccgcc tccgtgatcg tcacatttaa cacacgctca
    13381 tctgcgtgat cacgctctct ggtgaggtag cccttctgct ccagcttctt taacaccggt
    13441 gtcagcgtcc ccgaatccag gtacaaaagc gcccccatat ccttcacatt gatcctgcca
    13501 tgctcccaca gcaccatcat cgcaatatac tgcgtgtagg tcagatcaat ctcatccaga
    13561 tatggcttgt agcgccgcac gatctccttg gagcatgcgt acagcggaaa acagagttga
    13621 ttttctaatt ttaaagcatc atacttatct ttcattccgg cacctgtcgc ttataaatag
    13681 ttttcaatct tttcgcggac aacatccata tccgccgtcg gctcaaaacg ctccaccacg
    13741 tttccgtctc tgtcaatcaa aaacttggta aagttccatt tgatgtccgg tgtctcctta
    13801 taatccggat gcgtgcgctc taacatgctt tccacgatcg tcgctaacgg atgttcctcg
    13861 tcaaatcccg caaatccctt ctgcgacttc agatactgat acagcggcag cgcatgctcc
    13921 ccgttgacat cgatcttccc gtagtgcgtg aatgtgattc caaagttgac atcgcagaat
    13981 gcaacgatct cctcgttggt tcccggtgcc tgatgttcaa actggtcgca cggaaaatcc
    14041 agaatctcaa atcccatatg tgttcactcc gtatcttctg tgtgctgtta ctgctccata
    14101 catcctttta cccatgcttc cagttcaggc ttcggcatga atccgacatt cttgcctgcc
    14161 accttgccgt cctttaagaa taaaagcgcc ggaatgtttg tgatgccgtt tgcgatcgca
    14221 agctgcgtat tctcatcggt atctgcattg taaaatgcca ccttaccgtc cagatcgcct
    14281 gacagttcct ccagtaccgg ggcaagcatc tggcacggtc cgcaccatac tgccgaaaag
    14341 tccaccactg ctgcctttgc ctgtaacgct tcgtccatat tgttgttctg aatcttctta
    14401 accatgataa tcctccttag atctctcttt ttttcttatc caggtactct gccgcggaca
    14461 gcgccgccac atttccctgt cctgccgcct tgatatactg atacggcttt ccggtaatgt
    14521 ctccgcatgc aaagagtccc ggaaggtttg tctccatctg gagattaacc tttacgtgat
    14581 tctcctccgt cgcaagtccc ggcacgagct gtgacggtgc gatcgcgtct cttaagataa
    14641 atacgccgtc caccggatgc gtacctgcgt ccgtctcaag cgcacttacc gtctgcgtgc
    14701 ctgtgatcgc tttcggccgc tcatgcacaa cctctacggc atccgacagc tgcggctcct
    14761 cttttcccat cgggaaataa tgcacctttc cgacaatctc cgccagatag tctgcttcct
    14821 gctctgcctc cctgccgtat ccgatcaccg caacttcctt tccgcggaag aactgcgcat
    14881 cacaggtcgc gcagtagctg acgccgcttc caagcagctt gttttctccc gggaacggtt
    14941 ttcccatgac gcttcctgct gccagaatga cggtggacgc ctcaagaatc tcgccggacg
    15001 cctggatccc aaaataatct cccatcgcat agaccgcgtt cacgcgcttc tccgtcacct
    15061 cgatgccaag acctgctaac tgcttcttgt accctgcaac cagatctgct cctgaaactt
    15121 ccggcagccc tggatagttt aaaatctgat gcgccttgct catcttctcg ctgagttctc
    15181 tgctgccgat taacagtaca cttttatttc tcactttcgc ggtaatcgct gccgacacac
    15241 ctgccggtcc cgttccaata atggcaatat ctactcgttc cataccgttc tccattcccc
    15301 atatcgctct gcatctataa taatgcaaga atctgtcgtt ccagttcgtt catatctcct
    15361 gttggttcaa atcttaccac taccgtgccc tgcctgtcca caaggaactt cgtaaaattc
    15421 catttgatgt cggggttctc cttataattc ttatctattt tgcggagcat tattcccatc
    15481 gccgccgctt tcgccacttt tcctcataag tggacaacgg ctgcattgtc ccgtccggcc
    15541 gctccacaga ataatcataa atgcccatct cttaccctcc tttctctttg tccttaaaaa
    15601 tgaatgtgtt taaattgttt catttttaat tgtacgcaat ct
//
