LOCUS       gnlProkkaLIEHNEOO_10   21589 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LIEHNEOO_10.
ACCESSION   gnlProkkaLIEHNEOO_10
VERSION     gnlProkkaLIEHNEOO_10
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 21:54:15
            Original ID  :: gnl|Prokka|LIEHNEOO_10
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 137
            Orig. end    :: 21726
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21589
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:11589]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11589
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..21589
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21589
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     CDS             484..1434
                     /locus_tag="ctg10_2"
                     /transl_table=11
                     /translation="MQKDYETFVEKLEIGIYEATGIPKENISFEKEGGRFAPVGDRLLV
                     KFAEHDDAWEVCGLYTQELFKSYQNGSPFEEIIKEITDDLNRIKKADIYEKTRVIRDYE
                     KTKPRLFIRLLNADKYSADLQDAVYKTLGDIALVLYMKVTEYEGCVTSTKIRQGMLEQW
                     GKECDEVFQEAILNTYFMSPPRIYRWEQMIFNPEYEGESFMNLGDKCELKKDAMGNCLS
                     TTKKTNGAVAVFLPGVAEQLAYMLDSDFYMVFTSVHEVMIHNDKFVEPEDLQCVLRDTI
                     REATPKEDYLTSRIYQYNRETHKFICVTPLEKDEK"
     CDS             complement(1509..2303)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 169; E-value:
                     2.3e-51)"
                     /gene_kind="transport"
                     /locus_tag="ctg10_3"
                     /transl_table=11
                     /translation="MLELKNIYKTFNPGTINEKRALNGLNLKLNEGDFVTVIGGNGAGK
                     STMLNAVAGTWPVDEGQILIDNVDVTKLSEHKRATYLGRVFQDPMTGTAATMGIEENLA
                     LAKRRGKSRLLRSGITKAEREEYKELLKILGLGLEDRLTSKVGLLSGGQRQALTLLMAT
                     LQKPKLLLLDEHTAALDPKTAAKVLEITDMIVNRDHLTTLMITHNMKDAIAHGNRLIMM
                     MEGKIILDIQGEEKKKLTVKNLLDQFEKASGEEFSNDSALLG"
     CDS             complement(2306..3223)
                     /gene_functions="transport (smcogs)
                     SMCOG1113:inner-membrane translocator (Score: 62.6;
                     E-value: 5.1e-19)"
                     /gene_kind="transport"
                     /locus_tag="ctg10_4"
                     /transl_table=11
                     /translation="MQIITLITALPGAVAQGLIWGIMAIGVYITFRILDIADLTVDGTM
                     CTGGAVCIMMMLSGHNVWISMLAATLAGMLAGLATGIFHTFMGIPAILAGILTQLSLYS
                     VNLKIMGKANQAINVDKYNLLVSLRHIKNASLSKNTIFIVAVMCILLIAILYWFFGTEL
                     GCSLRATGCNPNMSRAQGINTNMNKVLGLMISNGLVGLSSALLAQYQGFADVNMGRGSI
                     VIGLAAVIIGEAIFGRIFRNFALRLLAVIFGSILYYLVLQIVIWMGIDTDLLKMLSAIV
                     VALFLAFPYWKGKYFNKPAKRGGK"
     CDS             complement(3374..4450)
                     /locus_tag="ctg10_5"
                     /transl_table=11
                     /translation="MKRKALAITLAAAMAMGTCAVTASAADGDKYTIGICQLVQHEALD
                     AATQGFKDEVTKELGEDAVTFDEQNAQGDSNTCSTIINSFVSNNVDLILANATPALQAA
                     AAGTSDIPILGTSVTEYGVALGLDDFDGTVGGNISGTADLAPLDQQAAMLNELFPDAKN
                     VGLLYCSAEANSQYQVDTVKAELEKLGYTCEYYAFSDSNDLSSVATTATDASDVIYVPT
                     DNTVASNTEIINNICLPAKVPVITGEEGICSGCGVATLSISYYDLGVTTGKMAVKILKD
                     GEDISTMPIEYAPNFTKEYNKDICEELGIEVPDDYVAIGEAXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXAK"
     CDS             4714..5571
                     /locus_tag="ctg10_6"
                     /transl_table=11
                     /translation="MAYSIMLDAGHGGQDPGAVYKGRQEKNDNLKLALAVGEILKNKGI
                     DISYTRTGDVYQTPFEKAQLANQAGVDYFISFHRNSSPKENQYNGAEVLIYDKSGIKYQ
                     MAENILGALGEVGFREIGVKERPGLVVLRRTRMPALLIETGFINSEEDNKLFDNKFSDI
                     AQGIADAILGSLDEETVQEPLYYRVQTGAFRKKENADRMLYQLLEKGYPSFMLHENGLY
                     KVQTGAYQQIGNAVNMEQRLRDDGYSTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXEQ"
     CDS             5743..6387
                     /locus_tag="ctg10_7"
                     /transl_table=11
                     /translation="MRGAVEKTDNEELVMMNDVYEKFLKSSEEFIFAENKPEKSDIIFV
                     PGNGYPQMAEKAAELFKKGMADWILPSGKYSVVNGKFSGVLEKSNVYNKEYGTEWEFLR
                     DVLIKNGVPDQKILKEDQATFTYENAIYSRQVTDHAELEIERAILCCKSYHARRCLMYY
                     QLLYPKTEFYVVPVNADGITRENWRKNEEGIDAVTGELSRIVKQFSLMLER"
     CDS             complement(6391..7308)
                     /gene_functions="other (smcogs) SMCOG1273:hypothetical
                     protein (Score: 270; E-value: 6.3e-82)"
                     /gene_kind="other"
                     /locus_tag="ctg10_8"
                     /transl_table=11
                     /translation="MSLAYSRIIYGLMILLTPVVFIVNKITEGVLVILHVNPDEKANAM
                     TEHELRTLVNVGEKDGVIENEEKQMIYNVFDFGDSTAKDVMIPRIDMTFIDINFSYDEL
                     MAVFSEDMHTRFPVYEDNTDNVIGIINMKDLLVYPKDKPFSIRNILREPYFTYEYKATA
                     DLMIEMRKASVNLAIVLDEYGATAGLVTLEDLLEEIVGEIRDEYDEDEVEDIKEIQPER
                     EYVVQGSAKLDDINEALHINLESEDYDSIGGYIIEQLDCLPKEGQSVTLESGIRLVVDR
                     LDKNRIELVHIWLPEKKTETEEQP"
     CDS             8019..9527
                     /locus_tag="ctg10_9"
                     /transl_table=11
                     /translation="MSNNINRIRKNKLKGTGIFAAAALTAALIAGNNIPGVTRQVSAAE
                     SQENTVSSLIPDNITLDKPVELADVELPATEYGTFEWADGSFVPAQRVQSCEVLLIPAE
                     GQDLSHVDGWDPESGAVVGYINVIVNSITDSDNVDKTEGSGKTDPTENADPTETPETSS
                     EKPAADENADTDNKEDKESKSDQDNKTDTDNEENKIEEDKTDNKNNKDNNSNADKTDKD
                     TETTGKLEPADDMTQDKEDTKKDDEDGAGDNIFDNPVLPDDKDDRPTDAEDSLSDEEKE
                     ERAALNHTCDGITVSGVNLPWYVQFRVSSGDSYQFTNESDAMIFQSYEFELWDLKNNTE
                     YEIPNGDYISVTVPVKSGYQYTIEHLLDNGATETIIPSVENGIMVFSTHSFSPFGIAGS
                     RQLVGPDAGNDTDDTDAVTPAPASSDSQSSDSGKNNTVSVNDSSDSNNGSSSDQNDNST
                     ENKAVKNNNTVNTGDTTSIMPFVILFVAAAVIAGVAVFIKKRKK"
     CDS             9577..9927
                     /locus_tag="ctg10_10"
                     /transl_table=11
                     /translation="MKVRAILKSLLFAYALTGVALLLLALVLFAFDLGETAVDAGIIII
                     YVLACFMGGFMAGKIVRKDKYLWGVITGLAYYVLLLTVSVMAKGGWDMSAAHAVTTFFM
                     CTGGGTLGGMLS"
     CDS             10001..10141
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR03973"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SCIFF"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg10_11"
                     /sec_met_domain="TIGR03973 (E-value: 5.7e-28, bitscore:
                     87.3, seeds: 29, tool: rule-based-clusters)"
                     /sec_met_domain="SCIFF (E-value: 7.2e-28, bitscore: 87.0,
                     seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEHIKTLNTKNLQNTVKKGGCGECQTSCQSACKTSCTVGNQSCEQ
                     K"
     CDS             10222..11589
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg10_12"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 2.8e-29,
                     bitscore: 92.0, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 1.9e-16, bitscore: 51.3,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.6e-14, bitscore: 45.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 4.2e-20, bitscore:
                     62.7, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLIHRYKSNGFNIVLDINSGCIHLVDEVTYEVLPYLEEGLGTEA
                     IAEKLENKYNREDIETSVRECNKLKEDGMLFTKDVYENVIEEFSNNRQTVVKALCLHIA
                     HDCNLACRYCFAEEGEYHGRRALMSYEVGKKALDFLIANSGSRKNLEVDFFGGEPLMNW
                     QVVKDLVKYGREQEKLHNKKFRFTLTTNGVLLNDEVMEFCNKEMGNVVLSVDGRKEVHD
                     YMRPFRKGAGSYDLIMPKFQKFAESRNQDKYYVRGTFTHHNLDFSKDVLHLADLGFKQI
                     SVEPVVAADTEEYAIREEDIPQIMEEYDTLAKEMIKREKEGKGFNFFHFMIDLTGGPCV
                     YKRLSGCGSGTEYLAVTPWGDFYPCHQFVGEEQYLMGNVDEGITKPEIQKEFGGCNVYT
                     KKDCKDCFARFYCSGGCAANAFHFQGDIKGNYEIGCELQRKRVECAIMIKAALACD"
     CDS             11701..14109
                     /locus_tag="ctg10_13"
                     /transl_table=11
                     /translation="MKKSKGIVVLLLTLILTVFFCFTAAVGIGPTGTGAAKHINTGLDL
                     AGGVSITYQAKESNPTSEEMSDTIYKLQKRVEQYSTEAQVYQEGSDRITVEIPGVTDAD
                     TILNDLGKPGSLYFITKEDADGNQNFTTGQDGYVLSRTMDEIKESGSVVLEGSDVADAQ
                     GGAIQNQNTSAKEYVVSLTLTSDGENSGKTKFAEATKNNVGKQIAIVYDNNIISAPNVN
                     EEISGGKAQISGMSDLEEAQNLASYIRIGSLGLELEELRSSVVAAQLGEEAISTSVLAG
                     AIGLIIVIIFMIIAYRVPGVVAGIALILYTSLMLITLNAFDITLTLPGIAGIILGIGMA
                     VDANVIIYARIREEIGAGVSVRNSIKSGFSKAFSAIFDGNITTLIAAFVLMWLGSGTVK
                     GFAYTLALGIVISMFTALVVSRLIVNALYAVGVRDPKFYGSAKERKAVDFLGKKKVFFA
                     ISIILILCGPAAMFANSHAGNKALNYSLEFSGGTSTTVTFNEDMDIKTIDSEVTPVVEE
                     VTGDKNVQPTKVVGTNQVVIKTRSLNQSEREALQSALVEKFGVDDSTISTESISSTVSS
                     EMRRDAIVAVIVATICMLLYIWFRFKDIRFASSAVLALLHDVLVVLAFYAIARVSVGNT
                     FIACMLTIVGYSINATIVIFDRIRENLHSGSREKLAEIVNTSITQTLTRSIYTSFTTFV
                     MVAVLYIMGVSSIREFAAPLMVGVLVGAYSSVCITGALWYVMKKKFAGKGQPAIAAASA
                     SAKSSSKPKKARDVSQKDPTQPKKKNRKRVAERLAAEEAAKKQQNDDAE"
     CDS             14293..15903
                     /locus_tag="ctg10_14"
                     /transl_table=11
                     /translation="MIGEDKIREYLSGTVQELPSPWLMKDMEKAVDILEKKISQKAKVR
                     IIGDYDIDGVTSTYILMKGLARIGADVDTYIPDRVADGYGIHAHLIERAETDRIDTIVT
                     CDNGIAAAAEIQMAKDKGMTVIITDHHEVPYREEKGERQMVLPPADAILNPKQYDCPYP
                     NKNLCGAVVAFKYIAALYERFGVPAEELEDYYELAAIATVGDVMDLQGENRILVKEGLY
                     RLKNTKNQGLQELIRANSLEDAKITAYHIGFVLGPCINASGRLDTAARSLALLNAKTKE
                     EAARLAGDLTALNQSRKALTEKGKEEAIRIIETTELKNDRVLVVYLPDCHESLAGIIAG
                     RIREKYHRPAFVLTGGETSAKGSGRSIESYSMYEELVKCADLMIQFGGHPMAAGLSIEE
                     KNIEEFRRRLNVNCTLTDEELRPKIVIDVPMPVSYITKELVEQISLLEPFGKGNTKPVF
                     AQKNLRVLDYSIIGKNKNVVKLKLLDPQGISVEGIYFGEAEDFVNFIREKDSISVTYYP
                     EINRFRGRESLQIIIQNYC"
     CDS             16051..16575
                     /locus_tag="ctg10_15"
                     /transl_table=11
                     /translation="MKKIEDYVLSIPDFPEPGIIFRDITSVLQDADGLQLAIDSMQDCL
                     KDIDVDVIAGTESRGFIFGVPIAYNLHKPFVPIRKKGKLPRETVSVSYDLEYGSAEIEM
                     HKDSIKPGQKVVIVDDLIATGGTIEAAIKLVEQLGGEVVKVVFLMELAGLKGRERLNGY
                     DVASVICYDGK"
     CDS             16613..18943
                     /locus_tag="ctg10_16"
                     /transl_table=11
                     /translation="MTEITKSTEAKKDEMQVEKEKLESVKRADAAVKTMHDFTSPEVLY
                     KELINSVLKYHPSTDISMIEKAYKVASEAHEGQKRKSGEPYIIHPLCVAIILADLELDK
                     ETIVAGLLHDAVEDTWMTYEEVEKEFGSEVALLVDGVTKLGQLSYSADKVEVQAENLRK
                     MFLAMAKDIRVILIKLADRLHNMRTLQYMRPEKQQEKARETMDIYAPIAMRLGISKIKV
                     ELDDLSLKYLKPDVYYDLVHKVALRKSEREQFVGAIVKEVKKHMDDANIKAQVDGRVKH
                     FFSIYKKMVNQDKTIDQIYDLFAVRILVDTVKDCYAALGVIHEMYKPIPGRFKDYIAMP
                     KPNMYQSLHTTLIGPNGQPFEIQIRTYEMHRTAEYGIAAHWKYKESSDGKAPVGKSEEE
                     KLNWLRQILEWQRDMSDNKEFMSLLKNDLDLFADSVYCFTPQGDVKTLPSGSTPVDFAY
                     SVHSAVGNKMVGARVNGKLVPIEYEIKNGDRIEIITSQNSQGPSRDWLKLVKSTQAKNK
                     INQWFKKELKEDNILKGKEMLAQYARAKGFKIANYTKTQYLEAVLRKYGFRDWDSVLAA
                     IGHGGLKEGQVFNKLVEAYDKENKKNLTDEQVLEAASETQEKLHIAKSKSGIVVKGIHD
                     VAVRFSKCCNPIPGDEIVGFVTRGRGITIHRTDCVNVLNMSETDRTRLIEAEWQQPDTK
                     EKEKYTAEIQVYANNRTGLLVDLSKIFTERKIDLRSINSRTSKQEKATISMSFEIGSKE
                     ELRSLIEKIRQVESVIDVERTTG"
     CDS             19008..19637
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1170:metallo-beta-lactamase family protein (Score:
                     163.1; E-value: 9.6e-50)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_17"
                     /transl_table=11
                     /translation="MKNLELQKCILGPVYTNCYLLKNKETGELIIVDPADCPEKIEMKI
                     SRMNGKPVAILLTHGHFDHILAAQAVKEKYNIPIYACRQEEEMLREPSINMTVHYGQGC
                     SIVPDVFLEDLDVIRLAGFSVQMIHTPGHTKGSCCYYLKDEGVLFSGDTVFYGSVGRTD
                     FPGGSTAEIVRSLHKLVDSLPEETEVFPGHDASTTIGYEKRYNPFV"
     CDS             19630..21144
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_18"
                     /sec_met_domain="PF04055 (E-value: 1.3e-24, bitscore: 78.1,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCKIGILFENRDFEHDVYELIKAFYPEAEIHTLYENTEAEYDLRF
                     SVERDNDSYIIKYERTENLSKQETEQKGVISADILSKENAGCGIQDAHALRKENKDNIK
                     YALYQLLIKLTGRTLPWGNLTGIRPAKLAMGMIESGMKNTEAAREMRERYLVSPQKTAL
                     AITIANREREILKDIDYENGYSLYIGIPFCPSICLYCSFSSYPLKVWEKRTDEYVAALC
                     REVRETALMMKGRKLDTIYIGGGTPTTLLPHQIRKLLDTVGEAFGYEGLAEFTVEAGRP
                     DSITREKLMAIREYPVTRISVNPQTMNQETLDIIGRRHTVEQTKEAFHLARELGYDNIN
                     MDLIVGLPGEDIHMVERTLEQVRELAPDSITVHSLAVKRAARLNIFKEKYQEMSFENNQ
                     EIMDLTMKTAYEMGMGPYYLYRQKNMKGNFENVGYAKVDKAGIYNILIMEEKQPIIALG
                     AGGSSKLVFDHGQRIERVENVKDVSNYISRIDEMIERKRTAIATWL"
ORIGIN
        1 tccggcgcga gaggagcttg ctaagcatga gattgattgt aagggtaagc gcgcagttca
       61 actaacgaag gcagattatg ataaatatga ttatattctc ggtatggatt actggaatct
      121 gaagaatatg ttaagaatat tgaaatcgga tccagaggac aaggttaagc ttcttctgga
      181 ttatagtgat gatccgaggg atatcgcaga tccatggtat acaggtggat ttgatgtcac
      241 atattcggat gtggtggagg gctgtgaggc ttttctggaa tatctgaaag ataaaaagaa
      301 actgtaataa atattgtcga tgaaatttac tttacaaata gctgtggcta ttttatacta
      361 tgtctacagc gactcttaag ggggctttcg ctcccttatt ttcttttttc cgaaaacgga
      421 aagtcaacat tcaaatcagg gcatcctgcc cgtattattt tcaaagcaag aaaggaactg
      481 aatatgcaga aagactatga aacattcgta gagaaactgg agattggtat ttacgaggct
      541 acagggattc cgaaggaaaa tatttctttt gagaaagaag gcgggaggtt tgcacctgta
      601 ggagacagac tgctggtgaa gtttgcagag catgatgatg cctgggaggt ctgtggactt
      661 tatacacagg aactttttaa atcttatcag aatggcagtc cgtttgagga aattataaaa
      721 gaaatcacag atgatctgaa tcggataaaa aaggcggata tttatgagaa aacaagagtg
      781 atcagggatt atgagaagac aaaaccccgc ctgtttataa gattgctgaa tgcagataaa
      841 tattccgcgg atcttcagga tgcggtgtat aaaactcttg gtgatattgc acttgtgctt
      901 tatatgaaag ttacggaata tgaaggatgt gtgacaagta caaaaatccg gcagggaatg
      961 ctggagcagt ggggaaaaga atgtgatgag gtgtttcagg aggcgattct caatacgtat
     1021 tttatgagtc cacccagaat ttacagatgg gaacagatga tttttaatcc ggaatatgaa
     1081 ggtgaaagtt ttatgaatct gggtgataag tgtgaattga agaaagatgc aatgggaaat
     1141 tgtctcagta caacgaagaa aacaaatggt gcagttgcag tgttcctgcc gggagtggca
     1201 gaacaattgg catatatgct ggattccgat ttctatatgg tgtttaccag tgtacatgag
     1261 gtaatgatcc ataatgataa atttgtagaa cctgaagatt tgcagtgtgt tttgcgggat
     1321 acgatcaggg aggctacacc gaaagaggac tatctgacgt cgagaatcta ccagtacaat
     1381 agggaaacac ataaatttat ctgtgtaact ccgctggaaa aagatgagaa ataaaaatat
     1441 gagagtactc cataaaaaag tactctcata taaaggatat ttagaaacgt tatgagtaat
     1501 ttatacggtt atccgagcag tgcagagtca ttgctgaact cttctccgct tgctttttca
     1561 aactgatcca gaaggttttt aactgtcagt tttttctttt cttctccctg gatatccaga
     1621 atgatttttc cttccatcat catgattaga cgattgccat gtgcaatagc gtccttcatg
     1681 ttgtgggtga tcatcaatgt tgtaaggtga tcgcggttta cgatcatatc tgtaatttcc
     1741 agaactttgg cagctgtttt tggatcaaga gctgcggtat gttcgtccag aagcagaagc
     1801 tttggtttct gaagcgttgc catcagaaga gtaagagcct gtctctgacc acccgagaga
     1861 agtcctactt tagaagtcag tctgtcttcc agaccaagac caagaatttt caggagctct
     1921 ttgtattctt cgcgctcagc tttagtgatt ccggagcgga gaagacggga ttttccgcgg
     1981 cgttttgcaa gtgcaaggtt ttcctcgata cccattgttg cagcggttcc tgtcattgga
     2041 tcctgaaaca cacgtccaag gtatgtagca cgtttatgtt cagaaagttt tgtaacatca
     2101 acattgtcga taaggatctg tccttcatca accggccagg ttcctgcaac agcatttagc
     2161 atagtagatt tgccggcgcc gtttcctccg ataacagtta caaaatcgcc ttcgttcagc
     2221 ttcaggttca gaccatttaa tgcacgtttc tcattaatgg ttccgggatt aaaggtttta
     2281 tagatatttt taagttcaag catttttatt tacctcccct tttggctggt ttattaaagt
     2341 atttgccttt ccagtatggg aatgcaagga agagagcaac tacgattgcg gacagcatct
     2401 tcagcaggtc agtgtcgata cccatccaga taacaatctg aagtaccaga taatacagaa
     2461 tggaaccgaa gataactgct aacaagcgaa gggcaaagtt gcggaaaata cgtccaaaga
     2521 ttgcctcgcc aataataact gctgccagac cgataacgat ggaaccacgt cccatgttga
     2581 catctgcaaa tccctgatac tgtgcaagga gtgcactgga aagtcctacc agaccgttgg
     2641 aaatcataag tccgagaact ttattcatgt ttgtgttgat accctgggcg cgtgacatat
     2701 ttgggttaca tccggttgcg cgaagggaac agccaagctc tgttccaaag aaccagtaga
     2761 gaatggcaat caggagaata cacataactg ctacaataaa aattgtgttt ttggaaagag
     2821 atgcattttt tatatgtcgc agggaaacca gaagattata tttatcaacg ttgattgcct
     2881 gatttgcttt tcccatgatc ttcaggttta cggaatacag agataactgt gtcaggattc
     2941 cggcaaggat tgcgggaatt cccataaagg tgtgaaaaat tccggtcgca aggcctgcca
     3001 gcattccggc gagagtagcg gccaacatag aaatccagac attatgaccg gaaagcatca
     3061 tcataataca cactgcacca ccggtgcaca tagtgccatc aactgtaagg tctgcaatat
     3121 caagaatacg gaaagtgata taaacaccga ttgccataat tccccagatc agaccctggg
     3181 ctactgcacc cggaagtgca gtgattaatg ttataatttg catttgtaat ttcctcctgt
     3241 tgagatgcga aaagcgagag aggcgtcaaa cctttcccgc tgatcgcata taaattgaat
     3301 tttttataac tgtttgataa gctgttattt aaaatcctgt tggtgtgagt atttttcaac
     3361 tgtctgaccg gatttatttg gcagnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     3421 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     3481 nnnnagcctc gccgattgca acataatcgt ccggaacttc gatgcccagc tcttcgcaga
     3541 tatctttgtt atattctttt gtgaagtttg gtgcatattc gatcggcatt gtggaaatat
     3601 cttcaccgtc ctttaaaatc ttaacagcca tcttaccggt tgtaacacca aggtcataat
     3661 agctgatgga aagtgtcgca acaccgcatc cgctgcagat accttcttcg cctgtgatta
     3721 ccggaacttt tgccggaagg cagatgttgt tgatgatctc tgtgttggaa gcaactgtat
     3781 tatctgtcgg tacataaatt acatcacttg cgtcagttgc tgttgtagca acagaagaga
     3841 gatcattaga gtcagagaat gcataatatt cacatgtata tccgagtttt tcaagttcag
     3901 cttttactgt atctacctga tactgagagt ttgcttcggc agaacagtag agaagaccta
     3961 cattttttgc atccgggaaa agttcattga gcattgctgc ctgctgatca aggggagcaa
     4021 ggtctgcagt tccggaaata tttccgccca cagtcccgtc gaaatcatcc agtccaagtg
     4081 caacaccgta ttcagtaaca gaagtaccaa gaatcggaat atcgcttgtt cctgctgcag
     4141 ctgcctgaag agcaggagtt gcatttgcaa gaatcaggtc aacattattg gaaacgaagc
     4201 tgttaatgat tgtagaacag gtgttggaat ctccctgtgc gttttgctcg tcaaaggtaa
     4261 ctgcgtcttc tcccagttct ttggtgactt catccttgaa tccctgtgtc gcagcgtcga
     4321 gagcttcgtg ctgcacaagc tgacagatac cgattgtata tttgtctccg tcagcagcac
     4381 ttgctgttac tgcgcaggtt cccatagcca tggctgctgc aagagtgatt gctaatgctt
     4441 ttcttttcat aatgatatat cctcctaata taatgtttaa attaagtcag gtaagaattg
     4501 cgtttattat ttgataatat aaaacttacc tgaatccgaa tgattttctg cagggaaagc
     4561 agtactggta aatgattcgg ataatgtcat cgagttattc gactgtgacg ttttaaagta
     4621 taacgcttta gtgtaaaaaa gtcaagcgac ctgcacaatt atatttttaa ttcatatagt
     4681 ataaagagta tatgaagaaa gcagagtgtc gtcatggcat attcgatcat gctggatgcc
     4741 ggacatggag gtcaggatcc gggagccgta tataagggaa gacaggaaaa gaatgacaat
     4801 cttaaacttg ctcttgcggt aggtgagatt ttaaaaaata aagggattga tatctcttat
     4861 acccgtaccg gtgatgtcta tcagacacct tttgagaagg cacagcttgc aaatcaggca
     4921 ggagtagatt actttatttc atttcaccga aacagcagtc caaaggaaaa ccagtataat
     4981 ggagcggaag ttctgattta tgataaaagc gggattaaat atcagatggc tgagaatatt
     5041 ctgggagctc tgggagaagt gggattccgc gaaatcggtg taaaagagcg gccgggactt
     5101 gtggtcctca gacgaaccag gatgccggct cttttaatag aaaccggatt tatcaattcc
     5161 gaagaagata ataaactgtt tgataacaag tttagcgata tagctcaggg aattgcagat
     5221 gcgattcttg gaagcctgga tgaggaaaca gtgcaggaac cgctttatta cagagtgcag
     5281 actggagcgt tcagaaaaaa agagaatgcg gaccgtatgt tatatcagtt actggaaaaa
     5341 ggttatccct cttttatgtt acatgaaaac ggattgtata aagttcagac aggtgcctat
     5401 cagcagattg gtaatgcagt aaatatggag cagagactga gggatgatgg ttacagtacg
     5461 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     5521 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn gtgaacagta acataagcag
     5581 tgggggatat agttttaaga attaacttgg ttgtacgtta atagaaaaaa tatggtacac
     5641 tgtatctatc tatagaaatt ccatagaaat cttcgtaaat aatgcatatt gttccggttc
     5701 atcaaagcgt gaatttttgt tggactgtta caaacgcatt atttgagagg tgctgtagaa
     5761 aaaacagata acgaggagtt agtaatgatg aatgacgtat atgaaaaatt tttaaaaagt
     5821 tcagaagagt ttatttttgc agaaaacaag ccggaaaaat ctgatattat ttttgtccct
     5881 ggaaatggtt atccgcagat ggcggaaaaa gcagcagaat tgtttaagaa agggatggcg
     5941 gactggattc tgcccagtgg aaaatacagc gtagtaaatg gaaagttttc aggcgttctt
     6001 gaaaaaagca atgtatataa taaggaatat ggaacagaat gggaatttct cagggatgtt
     6061 cttataaaaa acggagttcc ggatcagaaa atcctgaaag aagaccaggc aacctttact
     6121 tatgagaacg caatttattc cagacaggtg acagatcatg cagaactgga aatagaaaga
     6181 gcgattttgt gctgcaaatc ttaccatgca agaagatgtc tgatgtatta tcagctcttg
     6241 tatccgaaaa cagaatttta tgtggtgcct gtgaatgcag atggaattac cagagaaaac
     6301 tggagaaaga acgaagaagg aattgatgcg gttacaggag aactctccag aatcgtgaaa
     6361 caattttcac tgatgctgga gagatgacag ttacggctgt tcttctgttt cggttttctt
     6421 ctcgggaagc cagatgtgga caagttcgat tctgtttttg tccagacggt caacaaccag
     6481 gcggatgcca ctttcaagtg tgacagactg accctctttg ggaaggcagt caagctgttc
     6541 aataatatat ccgccaatag aatcataatc ttcagattcc agattaatat ggagggcttc
     6601 gttgatatca tccagcttgg cagaaccctg aacaacatat tctctttcag gctggatttc
     6661 tttaatatct tcgacttcat cctcatcgta ttcgtcgcga atctcaccta cgatctcttc
     6721 caacaggtct tccaatgtga ccagaccggc tgtggcaccg tattcgtcca gaacgattgc
     6781 cagattgacg gatgctttac gcatttcgat catcaggtct gctgtagctt tgtattcata
     6841 ggtaaaataa ggctcacgca ggatgttgcg gattgaaaaa ggtttgtcct ttggataaac
     6901 aagaagatct ttcatattga taataccgat tacgttatca gtgttgtcct cataaaccgg
     6961 aaaacgggta tgcatatctt cactgaagac cgccataagt tcatcatagg aaaaattgat
     7021 atctataaag gtcatgtcga ttctgggaat catgacatct tttgcagttg aatcgccaaa
     7081 atcaaacaca ttgtagatca tctgtttttc ttcgttttca atgacgccgt ctttttcacc
     7141 tacattgacg agggtacgca gttcatgttc agtcatggca tttgcctttt cgtccgggtt
     7201 aacatgcaga atgaccagta caccttctgt tattttattt acaatgaaaa caacgggagt
     7261 aaggagaatc ataagcccgt atattattct tgaataggcc agggacaatt tttcagcatg
     7321 aattgttgcc aggtttttgg gggttatctc accgaaaatg agaatcagca gagtcaggat
     7381 gccggttgtg attcctacat atgcgtttcc cagaatcttt atggtgagtg tagtcatgag
     7441 agaagaaaca gacatattta caatgttgtt tccgattaat acggtactga gcatctttgg
     7501 ggaattggaa attatttttt ccagaataac agcacgtttg ttgccctgct cggcaagaga
     7561 ctgtatccga atcttattta cggttgtcat agcggtttcc gcagaagaaa aaaatgaaga
     7621 aagtgcgatc agtatcagaa tcgccaccgc ctgaaaggca atacttgaat ccaagattta
     7681 ttcactcctt ttgattatct ttattgattg aatcatatca taaaacattt aagcaaaata
     7741 tacatgattt catataaaaa atcaagaaaa agcttttggt tcaaagatag tataaaaaaa
     7801 tttaaaagag gactgtcgaa aaagtaagat ttgtgttata attcactcga ttaaaatgaa
     7861 aaaaaacatt acagaatatt tacaaaatga taaaagtttg ataatataca gatatgtaat
     7921 attattgtat tacgtaaaaa gaaaactgat atttggccga aagtaaaaaa atgattatca
     7981 ggaaacataa gaatcgaata taaatataga ggtgcgatat gtccaataat ataaatagaa
     8041 taagaaaaaa taaattaaaa ggaacgggta tttttgcggc agcggcttta acagcggctt
     8101 tgattgcagg aaataatata ccgggtgtaa caagacaggt cagtgcggct gagtcacagg
     8161 agaatactgt gtcttctctg attccggaca acatcacgct tgataagcct gtagaacttg
     8221 cggatgtaga acttccggca acggaatatg gaacttttga atgggcagat ggaagtttcg
     8281 ttcctgcaca gcgtgtacag agctgtgagg tacttcttat accggcagaa gggcaggatt
     8341 taagccatgt ggatggatgg gatccggaga gcggcgcggt tgtcggttac atcaatgtaa
     8401 tagtgaacag tattacggat agtgataatg ttgataagac agaaggctca ggtaaaacag
     8461 atccaacaga aaatgcagat ccaacagaaa cgcctgaaac ttcgtcagaa aaacctgccg
     8521 cagatgaaaa cgctgataca gacaataaag aagataagga aagtaaatca gatcaggata
     8581 ataaaactga tacagacaat gaagagaata agattgaaga agataaaaca gataataaaa
     8641 acaacaaaga taataacagc aatgcagata agacggataa agatacagaa actaccggta
     8701 agctggaacc tgcagatgat atgacacagg ataaagaaga tacgaagaaa gatgatgaag
     8761 atggcgcagg tgataatatc tttgataatc ctgttctgcc ggacgataag gatgaccgtc
     8821 ctacagatgc agaggattct ctttctgatg aagaaaaaga agagagggcc gcacttaatc
     8881 atacctgcga cggtattaca gtaagtggag ttaatcttcc atggtatgta cagttcagag
     8941 tttcaagcgg tgacagctat cagtttacca atgaatcaga tgcaatgatt ttccagtctt
     9001 atgaatttga actctgggat cttaagaata atacagaata cgagatccct aatggagatt
     9061 atatcagtgt cactgtgccg gtaaaatccg gatatcagta tactatcgaa catctcctgg
     9121 ataacggggc aactgagacg attattccga gtgtagagaa tggtattatg gtattcagca
     9181 cacattcttt cagtccattt ggaattgcag gaagcagaca attagtagga cctgatgcgg
     9241 ggaatgatac ggacgacaca gatgcggtaa ctcctgcacc ggcttcctcc gacagtcaga
     9301 gctctgattc cggaaagaac aatacagtat ctgtgaatga cagttctgac agcaataatg
     9361 gttcttcttc tgatcagaat gataattcaa cggaaaataa agctgtgaaa aataacaata
     9421 cagtaaatac cggagataca acatcaatta tgccgtttgt gatactgttt gtggcagctg
     9481 cagtgatcgc cggtgtggct gtatttataa aaaagagaaa gaaataaaag aataacactg
     9541 attcctcccc catatagttt aacaggaggg gaagcaatga aagtcagagc aattttgaaa
     9601 tcactattat ttgcatatgc attaacagga gtggcattac tgcttttggc cctggtactg
     9661 tttgcttttg atctgggaga aacagctgta gatgcgggga ttattataat ttatgtactt
     9721 gcatgtttca tgggaggctt tatggccggc aaaattgtgc gtaaagacaa atatctgtgg
     9781 ggtgttatca caggtctggc ttactatgta ttactgttga ctgtctctgt tatggcaaaa
     9841 ggcggctggg atatgagtgc agctcatgca gttacaacat tttttatgtg cacaggcggt
     9901 ggaacactgg gtggaatgct gtcgtaaaaa aaagctttta aaatgaaaag atatatgata
     9961 tactatgcca agaatataat tacataagga ggatagagtt atggaacata tcaaaaccct
    10021 gaatacaaag aatttacaga acactgtaaa aaaaggtgga tgtggcgagt gccagacttc
    10081 ctgccagtcc gcatgtaaaa cttcctgtac agtaggaaac cagagctgcg agcagaaata
    10141 agatcagcta tggagaaatg agataagcag cggaactttt attccgctgc ttatcttacg
    10201 cttagaaagg attttagtaa aatgagtctg attcaccgtt ataaaagcaa tggctttaat
    10261 attgtactgg atatcaacag tggatgcatc catctggtag atgaggttac atatgaggtc
    10321 cttccatatc tggaagaggg ccttggcaca gaagctattg cagagaaact ggaaaacaaa
    10381 tataacagag aagatattga gacatctgta agagaatgta ataagctgaa agaagatgga
    10441 atgcttttta caaaagatgt ttatgagaat gtaattgaag aattttcaaa taaccggcag
    10501 accgttgtaa aagcattgtg cctgcacatt gctcatgact gcaatctggc ctgccgttat
    10561 tgttttgccg aagaaggcga atatcatggc agaagagctc ttatgtccta tgaagtcggc
    10621 aaaaaagctc ttgatttcct gatcgcgaac tccggttcca gaaaaaacct ggaagtagat
    10681 ttctttggcg gcgagccgct gatgaactgg caggttgtaa aagatctggt aaaatatggc
    10741 agagagcagg aaaagcttca caataagaaa ttccgtttca ctttaacaac aaacggagtt
    10801 cttctgaatg atgaagtaat ggaattctgc aataaagaga tgggcaacgt tgtactgagt
    10861 gtggacggac gtaaggaagt acatgattac atgcgtccat tcagaaaagg tgcaggaagc
    10921 tatgacctga tcatgccgaa gttccagaag tttgcagaat ccagaaatca ggacaagtat
    10981 tatgtaagag gtacttttac ccaccataat cttgatttct ccaaggatgt gcttcatctg
    11041 gcagatcttg gattcaaaca gatttctgta gagcctgtag ttgcggctga tacggaggaa
    11101 tatgcgatcc gcgaggagga tatcccccag atcatggaag agtatgatac tcttgcaaaa
    11161 gaaatgatta aaagagagaa agagggaaaa ggatttaact tcttccattt tatgatcgac
    11221 cttacaggtg gcccttgtgt atacaagaga ctgtcaggct gcggttcagg aacagagtac
    11281 ctggctgtaa caccctgggg tgatttttac ccatgtcacc agtttgttgg tgaagaacag
    11341 tatctcatgg gaaatgtaga cgaaggcatc acaaagccgg aaatccagaa ggaattcggc
    11401 ggatgcaacg tttacacaaa gaaagactgc aaagactgct tcgcacgttt ctactgtagt
    11461 ggcggatgtg cggcaaatgc attccatttc cagggagata tcaaaggcaa ttatgaaatc
    11521 ggatgcgaac tccagagaaa acgtgtggag tgcgccatca tgataaaagc cgcactggca
    11581 tgtgattagt gggcagtaat ctgtctgact gataccgccg tcggctgtta tcataacaga
    11641 aaatggctgg caggcggatg aacatgaccg cggacaaaaa atcaagaagg gaaaagaact
    11701 atgaagaaaa gtaaaggaat cgtagtgctg cttctgacac tgatcctgac tgtgttcttt
    11761 tgctttactg cagccgtagg tatcggtcct accggaaccg gtgcagcaaa acatatcaac
    11821 acgggtcttg atcttgccgg tggtgtcagc attacctacc aggctaagga gagcaatccg
    11881 acaagcgaag agatgtcaga tacgatctac aagcttcaga agcgtgtaga gcagtacagt
    11941 actgaggctc aggtatacca ggaaggatca gaccgtatta cagttgaaat tcctggtgtt
    12001 acagatgcag atactattct gaatgatctg ggtaaaccag gttccctgta tttcatcaca
    12061 aaagaagatg ctgacggaaa ccagaacttt actacaggac aggatggata tgttctctcc
    12121 agaactatgg atgagatcaa ggaatccgga agtgttgttc tggaaggttc tgatgtagca
    12181 gatgcccagg gtggtgcgat ccagaatcag aacacaagtg caaaggaata tgtggtaagt
    12241 cttactctta cttctgatgg agaaaacagt ggtaaaacaa aatttgcaga agctacaaag
    12301 aataatgtag gcaagcagat cgctatcgtc tatgacaata acattatcag tgctccgaat
    12361 gtaaatgaag agatttccgg cggaaaagca cagatcagcg gaatgtctga cctggaagaa
    12421 gcacagaacc ttgcttctta tatccgtatc ggttctctgg gactggaact ggaagaactt
    12481 cgttccagtg ttgtagctgc acagcttggt gaagaagcaa tctctacaag tgttcttgca
    12541 ggtgcgatcg gtctgatcat cgttattatc tttatgatca ttgcataccg cgtacctggt
    12601 gtagttgcag gtatcgcact gattctttat acatcattaa tgctgatcac gctgaatgcc
    12661 tttgatatta ctcttactct tccgggtatt gcgggtatta ttcttggtat cggtatggcg
    12721 gtggatgcca atgttattat ttatgcccga atcagagagg aaattggtgc aggagtttca
    12781 gtaaggaatt ctattaagtc cggtttcagc aaagctttct ctgcaatctt tgatggaaat
    12841 attacaacac tgatcgcagc ctttgtgctg atgtggcttg gttcaggtac tgttaaggga
    12901 tttgcttata cacttgccct tggtatcgtg atctccatgt ttacagcact ggttgtatcc
    12961 agactgattg taaatgcact ttatgcagtt ggtgtacgtg atccgaaatt ctacggatct
    13021 gcaaaagaac gtaaggcagt tgatttcctt ggaaagaaga aagtattttt tgctatttcc
    13081 attatcctga tcctctgcgg tccggcagcg atgtttgcta attcgcatgc aggaaacaaa
    13141 gcgttaaatt acagccttga gttctcaggc ggtacttcta caactgttac atttaatgaa
    13201 gatatggata ttaagaccat tgattctgaa gtaactcctg ttgtagaaga ggtgacagga
    13261 gataaaaatg ttcagcctac aaaggtagtc ggaacaaatc aggttgtgat caagacacgt
    13321 tctctgaatc agagcgaacg tgaagctctg cagagtgcac tggttgagaa atttggtgta
    13381 gatgacagca cgatttccac agaaagtatt tcttctacag taagtagtga aatgcgtcgt
    13441 gatgcgatcg tagccgttat agtagctaca atctgtatgc ttctttatat ctggttcaga
    13501 tttaaagaca tccgttttgc aagcagtgcg gtattggcgc ttctgcatga tgttctggtt
    13561 gtacttgcat tctatgctat tgccagagta tctgtcggta atacatttat tgcctgcatg
    13621 cttacgatcg taggttattc tatcaatgct acaatcgtta tttttgaccg tatacgtgag
    13681 aaccttcaca gtggttccag agaaaaactg gcagaaattg taaacacaag tatcacccag
    13741 actcttacaa gaagtattta tacctctttt acaacttttg ttatggtagc tgttctttat
    13801 atcatgggtg tttcttctat ccgtgaattt gcagcacctc tgatggttgg tgttcttgtc
    13861 ggtgcatatt cttctgtatg tattacaggt gcgttgtggt atgtgatgaa aaagaaattt
    13921 gcaggaaaag gacagccggc aattgctgca gcttccgcat ctgcaaagtc ctcttcaaag
    13981 ccgaagaaag cacgtgatgt atcacagaaa gatccgactc agccaaagaa gaaaaacaga
    14041 aaaagagtag ctgaacgtct ggctgccgaa gaagcagcta aaaaacagca gaatgatgat
    14101 gctgaataaa acaataattg tctgaaaaac aggcagacag aaatatcccg gggtaaaact
    14161 ccgggatatt tttatgagga gagaaaatat atggagaaat gggtaatagc agcaaaaaga
    14221 gcagatttta accagatcgg tcaacagttt catattgatc cggtgattgc gagactgatc
    14281 aggaacagag atgtgatcgg agaagataag ataagagagt atctgtcagg aacagtacaa
    14341 gagcttcctt ctccctggct gatgaaggat atggaaaaag ctgtagatat cctggagaaa
    14401 aaaatatcgc agaaagcaaa agtccgtatt attggtgatt atgatattga tggtgtgacc
    14461 tctacataca ttttaatgaa aggccttgcg aggatcggag cagatgtgga tacttatatt
    14521 ccggacagag ttgcagacgg atatgggatt catgcacatc ttatagaaag agcggaaacg
    14581 gaccggatcg atacgatcgt gacctgtgat aatggaattg ctgcggctgc tgaaatccag
    14641 atggcaaagg ataagggaat gacagtgatt attacagatc atcatgaggt tccttacagg
    14701 gaggaaaagg gagaacgcca gatggtgctt ccgccggcag atgcgatttt gaatccgaaa
    14761 caatatgatt gtccataccc gaataaaaac ctgtgtgggg cagtggtggc ctttaaatat
    14821 attgcagcac tttacgagag atttggtgtt ccggcagagg agctggaaga ttattatgaa
    14881 ctggcggcta ttgcaacagt aggagatgtt atggatcttc agggagagaa caggattctg
    14941 gtaaaagaag gactgtaccg tctgaaaaat accaaaaatc aaggattgca ggaactgatc
    15001 cgagcaaatt ctctggaaga tgctaaaatc acagcttatc atatcggatt tgtgctggga
    15061 ccatgtatca atgccagtgg cagactggat acagctgccc gttctcttgc gcttctcaat
    15121 gcaaaaacaa aggaagaagc agcaaggctt gccggagatc ttacagctct taatcagagc
    15181 cgaaaagctc tcactgagaa aggaaaagaa gaggcaatcc ggatcataga gactacagag
    15241 ctgaaaaatg acagagtact ggtagtttat cttccagatt gtcatgaaag tcttgccggt
    15301 attatagcag gcaggatcag ggaaaaatat cacaggcctg cctttgtatt gacgggcggt
    15361 gagacaagtg caaaaggaag cggaagatca atagaaagtt actctatgta tgaagaactg
    15421 gtaaaatgtg cagacctgat gatacagttt ggaggtcatc cgatggcagc aggtctttct
    15481 atagaagaaa aaaatataga agaattccgg agacgcctca atgtcaactg tacgttgacg
    15541 gacgaagaat tgcgtcctaa gatcgtgatt gatgtgccga tgcctgtgtc ttatattaca
    15601 aaagaactgg tagaacagat ttcgcttctg gaaccctttg gaaaagggaa tacaaaaccg
    15661 gtctttgcac agaaaaatct cagagtgctt gattacagta ttatcgggaa aaataaaaat
    15721 gtagtaaaat taaaacttct cgatccgcag gggatttcag tggaaggcat ttatttcgga
    15781 gaagcagagg attttgtgaa ctttatcagg gaaaaagaca gtatttctgt tacttattat
    15841 ccggagatca acagattcag gggacgagag agtcttcaga ttattattca gaattactgt
    15901 taatattacc gcctgttttg taaccgccgg taagcctgga aatacaaatg tcagggctta
    15961 acagtaactt gattctgaaa taaaaaggtg atatactata aaatatttat gagcgaacag
    16021 caatataaca cacactggag gagaaataaa atgaagaaaa ttgaagatta tgtattaagt
    16081 ataccggatt ttcctgaacc ggggattatt ttcagagata ttacaagtgt tctgcaggat
    16141 gcggatggcc tgcagttggc catcgactcc atgcaggact gtcttaagga tatagatgtg
    16201 gacgtgattg caggaacaga gtccagaggc tttatctttg gtgtaccgat cgcatataat
    16261 cttcataaac catttgtacc gattcgtaaa aaaggcaaac ttccccgcga aacagtatct
    16321 gtaagctatg atctggaata tggcagtgca gagattgaaa tgcataaaga ttccataaaa
    16381 ccaggtcaga aagtggttat cgttgatgat ctgatcgcaa caggcggtac gatcgaagca
    16441 gcgatcaagc tggtggaaca gcttggcggt gaggttgtca aggttgtatt tctcatggaa
    16501 cttgcaggtt taaagggacg cgaaagactg aatgggtatg atgtagcgtc cgtaatttgt
    16561 tatgatggta aataggcaca gctgattgtg caggacaggc aggtgggagc atatgacaga
    16621 gataacaaaa agtacagaag caaaaaaaga tgaaatgcag gttgaaaaag agaagctgga
    16681 atctgtaaag agagcagatg cggcagtaaa gaccatgcat gattttacaa gtccggaggt
    16741 gctttataaa gaactgataa acagtgttct gaagtatcat ccatcaacag atatttccat
    16801 gatagagaag gcatataagg ttgcaagtga agctcatgaa ggacagaaga gaaagtctgg
    16861 agagccatat atcattcatc ctttgtgtgt tgccatcatt ctggcagatc tggaacttga
    16921 caaagaaacg atagttgcag gtcttcttca tgatgcagtt gaagatacct ggatgaccta
    16981 tgaggaagtg gagaaggaat ttggttcaga ggttgcactt cttgtggatg gtgttaccaa
    17041 gctgggacag ttatcttatt ctgcggataa agtagaagtt caggcagaga acctcagaaa
    17101 gatgtttctt gccatggcta aggatatcag agttattctg atcaagcttg cagaccgtct
    17161 tcataatatg cgtaccttac agtatatgcg tcctgaaaag cagcaggaaa aggccagaga
    17221 gaccatggat atttatgctc ctattgccat gcgtctgggt atttccaaga taaaggtaga
    17281 gctggatgac ctgtcgctga aataccttaa gccggatgta tattatgacc tggtgcataa
    17341 ggttgccctg cgtaaaagcg agagagaaca gtttgtaggt gcgattgtaa aagaagttaa
    17401 gaaacatatg gatgatgcca atattaaggc gcaggtggac ggacgtgtaa aacacttttt
    17461 cagcatctac aagaagatgg taaatcagga taagactatt gatcagattt atgatttatt
    17521 tgctgtccgt attcttgtag atacagtgaa ggattgttat gctgcccttg gtgtgatcca
    17581 tgagatgtat aagccaattc cgggacggtt taaagattat attgccatgc cgaaacccaa
    17641 tatgtatcag tcattgcata ccacattgat cggacccaac ggacagccct ttgaaatcca
    17701 gatccgtact tatgaaatgc acagaactgc agaatatggt atcgctgcac actggaaata
    17761 taaggagtcg tctgacggaa aggctcctgt aggtaagagt gaggaagaga aactgaactg
    17821 gctgcgtcag attctggaat ggcagagaga catgtctgat aacaaagaat tcatgagtct
    17881 tctgaagaat gacctggatc tttttgcgga cagtgtttac tgtttcactc cacagggaga
    17941 tgttaaaaca cttccaagcg gttctacacc ggtggatttt gcgtacagtg ttcacagtgc
    18001 agtcggaaat aagatggtag gtgccagagt taacggtaag ctggttccga ttgaatatga
    18061 gatcaaaaac ggcgaccgta ttgaaatcat tacttcacag aattctcagg gaccaagccg
    18121 cgactggctg aaactggtta agagtactca ggcaaagaac aagattaacc agtggttcaa
    18181 gaaggaatta aaagaagata atatccttaa gggcaaggag atgcttgcgc agtatgcgcg
    18241 tgcaaaggga tttaagatcg caaattatac aaaaacccag tatctggagg ctgttttgcg
    18301 taaatatggt ttcagggact gggattcagt acttgctgca attggtcatg gcggattgaa
    18361 agaaggtcag gttttcaata agctggtgga ggcatatgat aaggaaaata agaagaatct
    18421 gacagacgag caggttcttg aggctgcttc tgagacacag gaaaagcttc acattgccaa
    18481 gagtaagagc ggcattgtgg taaaaggaat ccatgatgtg gcagtccgtt tttccaagtg
    18541 ctgtaatcca atcccgggtg atgagattgt aggttttgtt acaagaggac gtgggatcac
    18601 aattcatcgt acagattgtg tcaatgtgct gaatatgtct gagacagaca ggacacgact
    18661 gattgaggca gagtggcagc agcctgatac caaggaaaaa gagaagtata cggctgagat
    18721 tcaggtttat gcaaataacc gtacagggct tcttgtggat ctttctaaaa tatttacaga
    18781 acgtaagatc gacctgcgaa gtatcaacag ccgtacaagc aagcaggaga aggcgactat
    18841 ttccatgagt tttgagattg gaagcaaaga ggaactgcgt tccctgatcg agaagatccg
    18901 tcaggtagag agtgtcattg acgtagagag aactacaggc tgatcatgga aaaatctgct
    18961 ggaacattat tttatggaac tgctgcagat tgacagaaag gaataacatg aagaatttag
    19021 aattacagaa atgtatatta ggacctgtat atacaaattg ctatctcctt aagaataaag
    19081 aaaccggaga actgatcatt gttgatcccg cagattgtcc ggagaagatt gaaatgaaga
    19141 tttcccggat gaatggaaaa ccggtggcga ttcttcttac ccatggacat tttgaccaca
    19201 ttctggctgc acaggcagta aaggagaaat ataatattcc gatttatgcc tgtcgtcagg
    19261 aagaggagat gctccgcgaa ccttcgatca atatgactgt acattatgga cagggatgtt
    19321 ctattgtgcc ggatgtattt ctggaggatc tggatgttat cagactggcg ggattttccg
    19381 ttcagatgat ccatacaccg ggacatacca aaggaagctg ctgttattat ctgaaagatg
    19441 aaggtgtatt gttcagcggt gatacagtgt tctatggctc tgttggaaga acggattttc
    19501 cgggtggaag tacagcagaa atcgtgagaa gtctccataa actggtagat tcgcttcctg
    19561 aagagaccga ggttttcccc ggacatgatg catctaccac tattggttat gaaaagaggt
    19621 ataatccatt tgtgtaaaat aggcattctg tttgagaaca gagattttga acatgatgtt
    19681 tatgaactga tcaaagcgtt ttatcccgaa gcggagatac atactcttta tgaaaatact
    19741 gaagcagagt atgacctccg cttcagtgtg gaacgggata atgacagtta tatcataaaa
    19801 tacgaaagga cagagaatct gtcgaaacag gaaacagagc aaaaaggggt aatttccgca
    19861 gacatacttt ctaaagagaa tgcaggctgt ggaatacagg atgctcatgc tctgagaaaa
    19921 gagaataaag ataatatcaa atatgctctg tatcagttgt tgataaaact gacgggcaga
    19981 actcttccat ggggaaatct gacaggaata cgtcctgcca aactggcaat gggaatgatc
    20041 gaatccggaa tgaaaaatac ggaagcagcc cgggagatgc gtgagagata tctggtaagt
    20101 ccgcagaaaa cagcgcttgc catcactatt gcaaacaggg aaagagagat tctgaaggat
    20161 attgactatg aaaatggata cagcctttat attggaatcc cgttttgccc aagtatctgt
    20221 ctgtattgtt ccttcagctc ctatccgctg aaagtgtggg agaagagaac agatgaatat
    20281 gtggcagctc tctgccggga ggtaagagag actgctctta tgatgaaggg aagaaaactg
    20341 gataccatct atattggcgg cggtaccccg actacactgc ttccacatca gatccgtaag
    20401 ctcctggata cagtgggaga agcttttggc tatgaaggac tggcagagtt tactgtggaa
    20461 gccggcagac cggacagtat tacacgtgaa aagctgatgg cgatcaggga gtatccggta
    20521 acaagaattt ccgtaaatcc acagactatg aatcaggaaa ccctggatat tatcggccgc
    20581 agacatactg tggagcagac aaaagaagcg tttcatctgg cacgagagct gggatacgat
    20641 aacattaaca tggatctgat cgtaggtctt ccgggtgagg atattcacat ggtagagcgg
    20701 actcttgaac aggttcgtga actggcaccg gacagtatta ccgtacattc actggcagtg
    20761 aaacgtgcag caaggctgaa tatttttaaa gagaaatatc aggaaatgtc ttttgagaat
    20821 aatcaggaaa ttatggatct gaccatgaaa actgcgtatg aaatgggaat gggtccttat
    20881 tatctgtaca gacagaagaa tatgaaggga aattttgaaa atgttggcta tgcaaaggtt
    20941 gacaaagcgg gaatttacaa tatactgatt atggaggaaa aacagcctat catcgcactg
    21001 ggggcaggcg gttcttccaa gctggtcttt gaccatggac agagaattga acgtgtggag
    21061 aatgtaaaag acgtttctaa ttatatttcc cgcattgatg agatgatcga gagaaaacgg
    21121 acagcaatag ctacctggct gtaggatgtg gaggtaacat tttggacaca gtacaaaaga
    21181 cagcggcagg ttcacagcag aggatcctgg aatttgacct tgcttctgaa ctgcatcatg
    21241 gaatgctggt aagtaatctg gcttatgcgg ttgcagagga gatgggactg ccgcatgaac
    21301 agtgctatga gcttgcaata gcaggaatgc tccatgatat aggaaagctg aagctgacaa
    21361 gttatattaa cggacaggag caggatcctc tggtgatcga ggaactgaag tatgtccgga
    21421 tgcattctac attgggatat gaggaactta aagggcaggg atattcggat tttgtattgg
    21481 agagtatcct gtaccatcat gagaattatg atggcagtgg atatccgtcc aataaagcag
    21541 gtgatgacat acccataggt gcccggatac tcagagtctg cgatgtata
//
