LOCUS       gnlProkkaPOPHFAJL_101   9699 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|POPHFAJL_101.
ACCESSION   gnlProkkaPOPHFAJL_101
VERSION     gnlProkkaPOPHFAJL_101
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 21:41:32
            Original ID  :: gnl|Prokka|POPHFAJL_101
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9699
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..9699
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[8309:9698]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      8310..9698
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..9699
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..9699
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     CDS             complement(2..316)
                     /locus_tag="ctg101_1"
                     /transl_table=11
                     /translation="MRESEASIRGRVMRDLIAHVTNDHLIGKKIKNGELRKKIGDSEPP
                     WKCPDCFSLDVIEMDNFSMEYLQAKENPNTEKVILQLHGGGYVGAMRNAYRMFAGLYNE
                     V"
     CDS             complement(352..1017)
                     /locus_tag="ctg101_2"
                     /transl_table=11
                     /translation="MSKCRNCNVEISDETERCPLCGSVLEYTGEVENMYPDVRVHTRKM
                     TMISKIYLFCALLVEVLLIYINVVTESQIAWSAITGLGFFYGYMLIRFAILGKTGYRAK
                     ITVLTLMAILIVIAIDFLVGYRGWSVNYALPSAIILVDVGIIICMIVNRRNWQSYMMWQ
                     IFMILCSIVPVILIFTGIVTAQLFALIAFAFSLFLFLGTLIIGDRRARVELKRRFHVR"
     CDS             complement(1010..2308)
                     /locus_tag="ctg101_3"
                     /transl_table=11
                     /translation="MKKQNKGVPTNRDIRWDRLDNTAHLFPVIAGESMSNVYRISVTLK
                     EEINPELLQRALDMVLPKFDGFNLRLRQGVFWYYFEENGKAAPKVRMENNFPCRYIQQN
                     KNRSYMFRVTYYKCRINLEVFHVLTDGMGGINFLKELTYQYLRLAHKDLQEKLGDSLSV
                     DTSLNREDSFLKNYKKSSAKGYQTKKAYLIRGEKLRPGEFGVMHGYMKIPELKRVCHAM
                     EISINEYLVSVYIWSVYTECLHGMPSKCPIRVAVPVNLRPYFNSITTKNFFVMVSAEFH
                     PTKETYTFAEVAAIVKESLRSQINRENLEKLFSYNVSNEKLLIARVVPLFLKNLAMKYV
                     YTTSALANTATITNIGNISVTEEYRPYVEMFHAFLAMSKGQHLKGTICSYGDTLVFSFS
                     YDLVDASVQRGFFRKIASDGIAVEIKSNGVNYE"
     CDS             2584..3330
                     /locus_tag="ctg101_4"
                     /transl_table=11
                     /translation="MKIFKRTVSLFLAFCLCAGMLLLQPQSTVSAAVRNKPTTTVLRMS
                     SNSFDSSAIYVNLPKAKVCYIKNIKTSSKNLIAKNTHYYTTSSDDTYTDTFASIGLYAK
                     KTGKYKVTYNICDKSGNKLSSGKVTVYVKNDLPVKSVKFAGKEVNYALTSKKSGKLSVK
                     MNKGYTLKKITVTTYNKAGKEVVKTMKNNSTLKLGEYAYIFDNSYSSGRNYSTSLAART
                     KITITYIDKYTKQECESIYSISRLAK"
     CDS             3352..4176
                     /locus_tag="ctg101_5"
                     /transl_table=11
                     /translation="MKLFKQITCAVLTLCLCAGLLLIPSAPVSAATGPSAPKAVDVSYY
                     KNYPMVNDSAISVQLGTNGKNIKNIKTSSKNLKAKVTRLSLSSSSNSGYVGVYAKKTGK
                     YTVSFDVYNAQNKKIKKFTVKVNVTEPTFSNNSPFKSVTFNNKEYDYAKAVYNKNSVKV
                     NVKMNKGYKLKKIEYSTYSKPVAKTNSSYSTTYSNSEITKKVKNGKSIQLGHYGYYYGH
                     DYSYAYGTYSYESYSRDGDIMAPTIVKITYLDKNKNTISTSYTLYRIADDVK"
     CDS             complement(4265..5506)
                     /NRPS_PKS="Domain: Aminotran_1_2 (77-368). E-value:
                     1.2e-15. Score: 49.4. Matches aSDomain:
                     nrpspksdomains_ctg101_6_Aminotran_1_2.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg101_6"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.9e-16, bitscore:
                     49.3, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYTLEDIQAVDMEVANAITDEFERQNSHIELIASENWVSKAVMSA
                     MGSVLTNKYAEGYPGKRYYGGCECVDVVEELARERAKELFGCEYANVQPHSGAQANMAV
                     QFAILKPGDTVMGMNLDHGGHLTHGSPVNFSGTYFHIVPYGVNDEGFIDYDKVEEIAME
                     CKPKMIIAGASAYARTIDFKRFREIADACGAVLMVDMAHIAGLVAAGLHPSPIPYAHVV
                     TTTTHKTLRGPRGGMILSSQEIADKYNFNKAIFPGIQGGPLMHVIAAKAVCFKEALQPE
                     FKVYQQNIIDNAQALCKGLLSRDIKIVSGGTDNHLMLVDLTNYDQTGKAVEKLLDSVNI
                     TCNKNTIPNDPKSPFVTSGVRLGTPAVTSRGLNTEDMDQIAEAIAMMIKEGEPAADKAC
                     AIVKSLTEKYPLER"
     aSDomain        complement(4403..5275)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg101_6_Aminotran_1_2.1"
                     /evalue="1.20E-15"
                     /label="ctg101_6_Aminotran_1_2.1"
                     /locus_tag="ctg101_6"
                     /protein_end="368"
                     /protein_start="77"
                     /score="49.4"
                     /tool="antismash"
                     /translation="RERAKELFGCEYANVQPHSGAQANMAVQFAILKPGDTVMGMNLDH
                     GGHLTHGSPVNFSGTYFHIVPYGVNDEGFIDYDKVEEIAMECKPKMIIAGASAYARTID
                     FKRFREIADACGAVLMVDMAHIAGLVAAGLHPSPIPYAHVVTTTTHKTLRGPRGGMILS
                     SQEIADKYNFNKAIFPGIQGGPLMHVIAAKAVCFKEALQPEFKVYQQNIIDNAQALCKG
                     LLSRDIKIVSGGTDNHLMLVDLTNYDQTGKAVEKLLDSVNITCNKNTIPNDPKSPFVTS
                     GVRLGTPAVT"
     CDS             complement(5646..5924)
                     /locus_tag="ctg101_7"
                     /transl_table=11
                     /translation="MDTIAAYLIFLNLVGFLIMGEDKRRAKMHRWRISERMLFLVSILG
                     GSIGTWAGMYVFRHKTRHWYFVMGMPLILILQIAGAIWLYRQGLYHL"
     CDS             complement(6125..8284)
                     /locus_tag="ctg101_8"
                     /transl_table=11
                     /translation="MKKSKAAVILVAILAAFAGLAYYASIILSSTGIGEEMSIPLGLDL
                     SGGVSITYQVMDENPSAEDMSDTIYKLQKRVESYSTEASVYQVGDDRIAVEIPGVTDAS
                     KILEELGNPGSLEFQLSDGTVFMTGDQVADAQAATTTDQYGNKQYVVQLTLTDEGAKTF
                     GEVTSENVGKALPIVYDGEVISYPTVQEAITGGTAQISGQSTFEEAQTLATQIRIGSLS
                     LQLSELESSVVGAQLGSQAISSSLKAAAIGLVIVMVFMIIVYAVPGVAAALALAIYTAL
                     VIATLYLFEITLTLPGIAGIILSIGMAVDANVIIFARIREEIASGKSVITAMKNGFHKA
                     MSAILDGNITTLIAAIVLMGLGSGTVKGFAYTLMIGIILSMFTALVVTRWILYSFYWLG
                     MRDEKFYGRAKERKTINFLQKRYVFFAISIAVIAAGFIGMGVHKASGQNSLNYGLDFMG
                     GTSTTADFGEEYTIEDIENDIIPVVKEVTGDSNIQANKVEGTTQITIKTRTLSKEERDD
                     LNNKLADSFDVDESTITFQSISSTISGEMRADAVKAVIISTICMLIYIWFRFKDIRFGA
                     SAIIALIHDVLVVLTVYALMRISVGNTFIACMLTIIGYSVNDTIVIFDRIRENLALKHG
                     KQTREDLMEVANRSLTQTLSRSINTSITTFIMVFMLFLLGVASIREFALPLMAGMICGA
                     YSSICIATELWYVMKVHLGKNKITE"
     CDS             complement(8310..9698)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Quinohemoprotein_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg101_9"
                     /sec_met_domain="Quinohemoprotein_rSAM_RRE (E-value:
                     6.9e-11, bitscore: 31.5, seeds: 15, tool:
                     rule-based-clusters)"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 4e-34,
                     bitscore: 106.2, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 3.9e-17, bitscore: 52.1,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 5.1e-14, bitscore: 42.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 6.4e-19, bitscore:
                     57.5, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGNIIVVHQYKNNGYDIVLDVNSGAIHVVDDVTYDVIEMIDQSQP
                     ESYARDEIVSALSGKYGKEEVEEAVDEVQTLIDEESLFTKDTYENYIMDFKKRPTVVKA
                     LCLHIAHDCNLACQYCFAEEGEYHGRRALMSFEVGKKALDFLIANSGNRRNLEVDFFGG
                     EPLMNWQVVKDLVAYGREQEKLHDKNFRFTLTTNGVLLNDEIMEFCNKEMANVVLSIDG
                     RKEVHDKMRPFRKGAGSYDLIVPKFQKFAESRHQDKYYVRGTFTHYNPDFAADVLHLAD
                     LGFKQISVEPVVAEPSEPYAITEEDLPQLFEEYDKLAAEMVRRHKEGDDFNFFHFMIDL
                     EGGPCVAKRLSGCGSGTEYLAVTPWGDFYPCHQFVGNEKFLLGNVDEGIKNTEIRDEFK
                     CCNVYAKEKCRKCFARFYCSGGCAANAYNFSGDICGAYDIGCELQKKRIECAIMIKAAE
                     ADCE"
ORIGIN
        1 tgacttcatt gtaaagtccc gcaaacatgc ggtatgcatt ccgcatcgct ccgacatatc
       61 cgcccccgtg aagctgtaag attacttttt ccgtattcgg attttctttt gcctgtaaat
      121 actccatgga gaaattatcc atctcgatca catctaatga aaaacagtcc ggacatttcc
      181 acggcggctc cgaatccccg atttttttcc tcagttctcc attttttatc tttttcccaa
      241 tcaggtgatc atttgtcaca tgggcgatca ggtccctcat gactcttccc ctgatactcg
      301 cttcgctctc tctcatccga ttgctcctgt tctttttatt ctaaatataa ctcagcggac
      361 atgaaatctt cgtttcagtt ccacccttgc cctgcggtct ccgatgatca gtgttccaag
      421 aaacagaaac agggaaaacg caaatgcgat cagtgcaaaa agctgtgccg tcacgatacc
      481 ggtaaaaatc agtattaccg gaacaatgct gcataaaatc ataaaaatct gccacatcat
      541 atagctctgc cagtttctgc ggtttacgat catacagatg ataataccaa catcgactaa
      601 aatgatcgcc gacggcaatg cataattgac agaccatccg cggtagccga ccagaaaatc
      661 gattgcgatc acgatcagta tcgccatcag cgtgagtacc gtgattttgg cgcggtaacc
      721 tgtctttcca agaattgcaa aacggatcag catatatccg taaaagaatc caagccccgt
      781 gatcgcactc catgcaatct gtgactcggt gaccacattg atataaatga gcagcacctc
      841 aaccaaaagt gcacaaaaca gatagatttt actgatcatt gtcattttcc gggtgtgcac
      901 tctcacatcc gggtacatat tctccacttc acctgtgtat tctaacacgg atccgcagag
      961 tggacagcgc tctgtttcat ctgatatctc cacattacaa tttctgcatt tactcataat
     1021 ttactccatt actctttatt tctaccgcaa tcccgtccga ggctattttc cggaaaaatc
     1081 cacgctgcac agacgcatcg acaagatcat aactgaaact gaatacaagt gtatccccgt
     1141 aagagcagat cgttcctttc agatgctgcc cctttgacat ggcaagaaat gcatgaaaca
     1201 tttccacata agggcggtac tcttctgtca cggaaatatt gccgatattt gtgatcgtcg
     1261 cagtattggc aagtgcagaa gttgtatata catacttcat tgcaaggttt ttcaggaaaa
     1321 gcggcacaac tcttgcaatc agcagttttt cattggaaac gttataggaa aacagctttt
     1381 caagattttc ccggttgatc tggcttcgca ggctttcctt cacgattgca gccacctctg
     1441 caaacgtata ggtctctttg gtcggatgaa attctgcgga caccatgaca aaaaagtttt
     1501 tcgtggtaat agaattaaaa tacggccgca gattaaccgg caccgcaaca cggatcggac
     1561 actttgacgg catgccgtgc agacattctg tataaacgct ccagatgtac acacttacca
     1621 gatattcgtt gatactgatt tccatcgcat gacagacccg tttcaactcc ggtattttca
     1681 tataaccgtg catcacgccg aactcgcccg gtcttaactt ttctccacgg atcagatatg
     1741 ccttttttgt ctggtatcct tttgcggaac tttttttgta attttttaag aaactgtctt
     1801 cccggttcaa agacgtatca acacttaatg aatctcccag cttttcctgc aggtctttat
     1861 gtgccagacg cagatactgg taagtcagct cttttaagaa attgattcct cccattccat
     1921 ccgtcaaaac atggaatact tccagattga tcctgcattt ataataggtc acacggaaca
     1981 tataactgcg gtttttattc tgctggatat atctacatgg aaaattgttc tccatgcgaa
     2041 cctttggcgc cgcttttccg ttttcctcaa aataatacca gaacaccccc tgccgcagtc
     2101 ttaagttaaa cccgtcaaac ttcggaagca ccatatcaag tgccctctgc agtaattccg
     2161 gattgatctc ctctttcagt gtaacactga tcctgtacac attgctcatg ctctccccgg
     2221 caatgaccgg aaaaaggtgt gctgtattat caagtctgtc ccaacggata tcacggtttg
     2281 tcggaactcc tttattctgt tttttcatat attcctcgtt tctgcatatt ttacaggcag
     2341 gctgggtttc tgttttttct tctctccccc cgctcataaa atacacaatc tattgtatgc
     2401 aattataaaa taacctgaca taaaatacaa gtttgggcat atcaaaatta cctgatataa
     2461 tgctataaat tttcttaaaa ttcccttatt tattttttaa tttatgattg tataaaattt
     2521 tccttcatat tataatgttt ttgtaacatc tataaaatat ttataaacaa gaaggattca
     2581 cttatgaaaa ttttcaaacg aacagtcagc ttatttttag ctttctgtct ctgtgccggg
     2641 atgcttttac tgcagccgca gtcaacggta tccgcagccg tcaggaacaa accgaccacc
     2701 actgtacttc gcatgtccag taattctttc gacagttctg caatctatgt caatctgcca
     2761 aaagccaaag tatgttatat caaaaacatc aaaaccagca gtaaaaatct gattgcaaaa
     2821 aacacccact attatactac cagttcagac gatacataca cggatacctt tgcgtctatc
     2881 ggcctctatg ccaaaaaaac cggtaaatac aaagtcacct ataatatctg cgataaatca
     2941 ggaaacaaac tttcttcggg taaagtaaca gtatatgtaa aaaatgacct gccagtcaaa
     3001 tctgtcaaat ttgcaggtaa agaagttaat tatgccctta cgagcaaaaa atccggcaaa
     3061 ttatctgtta aaatgaacaa aggttacacg ctgaaaaaaa tcactgtcac cacttacaat
     3121 aaggcaggta aagaagttgt aaaaacaatg aaaaacaaca gcaccttaaa gcttggcgag
     3181 tacgcatata tatttgataa ttcatattcc agcggcagaa actattctac ctcacttgct
     3241 gcgcgtacca agatcactat tacttatatc gacaaatata ccaagcagga atgtgagagt
     3301 atttattcca tttcccgtct tgcaaaataa tccaacagga ggatatctga tatgaaatta
     3361 tttaagcaaa ttacttgcgc tgttcttaca ctttgcctgt gcgccggatt attactgatc
     3421 ccttctgcgc cggtatctgc tgcaacaggt ccaagcgccc caaaggctgt agatgtttct
     3481 tattacaaaa attatccgat ggtcaatgat tcggctatct ccgtacagct cggtacaaac
     3541 ggaaaaaaca tcaaaaatat caaaacatcg agcaaaaacc tgaaagccaa agtaacaaga
     3601 ctttcacttt ccagctccag taattccgga tacgttggtg tctatgccaa gaaaaccggt
     3661 aaatacacag tatcttttga tgtatataat gcacagaata aaaagattaa aaaatttact
     3721 gtcaaagtca atgtaaccga gccgacattc tctaacaata gtccttttaa gagtgtaact
     3781 tttaacaaca aagaatatga ttacgcaaag gcagtctaca ataaaaattc tgtcaaagtc
     3841 aatgtcaaaa tgaacaaggg ttataaatta aagaagatcg aatactctac ttacagcaag
     3901 ccagttgcaa aaacaaattc ttcctattca accacttatt caaactccga gataacaaaa
     3961 aaggtaaaaa atggaaagag tatccagtta ggacattatg gatactatta cggacatgac
     4021 tactcttacg catatggtac ttactcttat gagtcataca gccgtgatgg tgatattatg
     4081 gcaccgacaa tcgtgaaaat cacatatctc gataaaaata aaaatacgat ttctacctcg
     4141 tacacactgt accgtattgc agatgatgta aaataacaaa ctcaaaggtc acaaaaaaag
     4201 aggaacctgt cacgaaacag gttcctcatt ttttattcat tattaaatta tattctattc
     4261 tcttttatct ctccagcgga tatttctctg tcagcgattt tacgattgca cacgctttat
     4321 cagctgccgg ttcaccctcc ttgatcatca tggcgattgc ctctgcaatc tgatccatat
     4381 cctctgtgtt tagtccacgg gaagtaactg ccggcgttcc aagacgtaca ccgcttgtta
     4441 cgaatgggga tttcggatcg ttcgggatcg tattcttgtt gcaggtaata ttgacagaat
     4501 cgagaagttt ctccactgcc tttccggtct gatcataatt tgtcagatca acaagcatca
     4561 ggtgattgtc tgtaccgccg gatacgattt taatatcacg gcttaacagt cccttgcaga
     4621 gtgcctgtgc attgtcaatg atattctgct ggtatacttt aaactccggc tgaagtgcct
     4681 ccttaaagca gactgctttc gctgcgatca catgcatcaa aggtccgccc tggattccag
     4741 ggaaaatagc tttgttaaag ttatatttgt ctgcgatttc ctgactggat aagatcatac
     4801 ctccacgcgg tccacgcagt gtcttgtgtg ttgtggttgt gacaacgtgt gcatacggga
     4861 ttgggcttgg atgaagtcct gcagcgacaa gtcctgcgat atgtgccata tcgaccatca
     4921 gaactgctcc gcatgcatct gcgatctcac ggaatctctt gaaatcaatg gttctcgcat
     4981 aagcacttgc acctgcgatg atcatcttcg gcttgcactc catcgcgatc tcttctactt
     5041 tgtcataatc aataaatccc tcgtcattga caccgtaagg tacaatgtga aaataagtac
     5101 cggaaaagtt tacagggctt ccgtgtgtca aatgtccgcc gtgatctaag ttcattccca
     5161 tgaccgtgtc acccggtttt aagatggcaa actgtacagc catattcgcc tgtgcaccgg
     5221 aatgtggctg tacgttcgca tactcacagc caaacagctc tttcgcacgc tctcttgcaa
     5281 gttcctctac aacatccaca cactcacatc cgccgtaata tcttttcccc ggataacctt
     5341 ctgcatattt atttgtaaga acactgccca tcgccgacat cactgccttg cttacccagt
     5401 tttcggatgc aatcagctca atatgactgt tctgacgttc aaattcatcg gtgatggcat
     5461 ttgccacttc catatcaact gcctgaatat cttccagtgt atacataatc cgtaattctc
     5521 cctttctttg ctgtttgatc aatgtgtctt tctacgaaaa acacttgttt tttgctatgt
     5581 ttatcattat atatgacttt cctttttttg gcaattccaa atgccagaat agttatatca
     5641 aattattata aatgatataa gccctgacga taaagccaga tggcacctgc gatctgtaaa
     5701 atgaggatca gcggcattcc cataacaaaa taccagtgtc tcgtcttgtg gcggaacaca
     5761 tacattcccg cccacgttcc gatactgccg cctaaaatgc tgactaaaaa caacattctt
     5821 tctgagatcc gccatcgatg cattttcgcc cttcttttat cctctcccat aataaggaag
     5881 cccaccagat ttaaaaagat cagataagct gcgatcgtat ccatatgttt ctcctttttt
     5941 ctaaaataga atcctgtcct acaggattca ccgcctgcgg cggtgtcgcc tccgcgacat
     6001 aattcatctc cgacgcagtg cgatcccgcc cggagggctt taagattcat aggacgtaat
     6061 ttccaatgaa tcttaaaagt cccggcaaat aactgccagg actttcactt ttcttcaaca
     6121 gatcttattc tgttatttta tttttaccaa gatgaacttt catcacatac cacaactcgg
     6181 ttgcaatgca gatagatgaa tatgcaccgc agatcatacc tgccatcagt ggcagcgcaa
     6241 attcacgaat acttgctaca ccaagaagga acagcataaa taccataata aatgttgtta
     6301 tggatgtgtt gatgcttcgt gataaggtct gtgtcaggct tcggtttgct acttccatca
     6361 gatcttccct tgtctgtttt ccatgcttta atgcaaggtt ctcacggata cggtcaaaga
     6421 taacgatcgt atcgttgaca gaataaccaa tgatcgtcag catacatgcg ataaatgtat
     6481 tgccgactga aatacgcatc agcgcatata cggtaagtac aaccagtacg tcgtggatca
     6541 gggcaatgat cgcactggca ccgaaacgga tatctttaaa acggaaccag atatagatca
     6601 gcatacagat tgtggagata ataaccgcct tgactgcatc cgcacgcatc tcaccactga
     6661 tcgtggaact gatactctgg aatgtaatgg tggattcatc tacatcaaaa ctgtctgcca
     6721 gcttattatt cagatcatca cgctcttctt tggataaagt acgtgtcttg atcgtaatct
     6781 gagttgttcc ctctactttg tttgcctgaa tattgctgtc tccagttact tcttttacaa
     6841 ccgggataat atcattttca atatcttcga tcgtatattc ttcgccaaaa tcagcggtag
     6901 tggaagttcc tcccataaaa tcaagtccat aattcaggga attctgacca gatgccttat
     6961 gtactcccat accgataaat ccggcagcta taactgcaat agaaattgca aagaatacat
     7021 atctcttctg caggaaattg atcgtctttc tctcttttgc acgtccgtag aatttttcat
     7081 ctctcattcc taaccagtag aaagaataaa ggatccatct tgtgacaaca agtgctgtaa
     7141 acatggaaag gataataccg atcatcagtg tatatgcaaa tccttttaca gtaccggaac
     7201 ctaatcccat aagaacaatc gctgcaatca atgttgtgat attaccatct aagattgcag
     7261 acatcgcttt gtggaaacca ttcttcattg cagtaatcac ggattttcct gatgcaattt
     7321 cttcacggat acgtgcaaag atgataacgt tcgcatccac tgccatacca atacttaaga
     7381 taataccggc aataccaggt aatgttaatg tgatctcgaa taagtataaa gttgcaatca
     7441 caagtgctgt ataaattgca agtgctaaag ctgctgcgac acccggaact gcatatacaa
     7501 tgatcataaa taccattacg atcacaagac cgattgctgc cgcttttaaa ctggaggaga
     7561 ttgcctggct tccaagctgt gctcctacca cactggactc taactctgat aactgcaggg
     7621 aaagagaacc gattctgatc tgtgttgcta aagtctgtgc ctcttcaaag gtgctctgac
     7681 cggaaatctg tgcagtacct ccggtaattg cctcctgaac agtcggataa ctgataactt
     7741 ctccatcgta tacgattgga agtgcttttc cgacgttttc agaagtaact tctccgaaag
     7801 tctttgctcc ctcatctgtc agtgtaagct gtaccacata ctgcttgttt ccatactgat
     7861 ctgtggttgt tgcagcctgt gcatctgcca cctggtcacc cgtcataaat acggtaccat
     7921 ctgaaagctg gaactctaag gaacccggat taccaagttc ttccaaaatc ttgcttgcgt
     7981 ccgtaacacc cgggatctca acggcgatac gatcatctcc aacctgatat acggatgcct
     8041 ctgtactgta actttccaca cgcttctgga gtttgtaaat cgtatcactc atatcctctg
     8101 cgctcggatt ttcatccatg acctgatagg tgatcgatac accaccggac agatcaagtc
     8161 caagcggaat actcatttct tccccaatac cagtcgatga aagaataata gatgcataat
     8221 aggcaagtcc cgcaaatgca gcgagaatcg caactaatat gactgctgct ttactctttt
     8281 tcattttctt tttccttcct gtttcttatt tattcacaat cggcctcggc agccttgatc
     8341 atgatcgcgc actcaatacg ttttttctgc aattcacatc cgatatcata tgccccacag
     8401 atgtcaccgc tgaaattata cgcatttgct gcacatccgc cgctgcagta gaatcttgcg
     8461 aaacattttc tgcatttttc ttttgcatag acattacagc acttaaactc atcacggatc
     8521 tctgtatttt ttataccttc atccacattg ccaagtaaaa acttttcatt gccgacaaac
     8581 tggtgacatg gataaaaatc tccccatggt gtcactgcaa ggtactcggt tcctgaacca
     8641 cagccggaca gacgttttgc cacacatgga ccgccctcaa gatcgatcat aaaatggaag
     8701 aaattaaaat catctccctc tttgtgacgt cttaccatct ccgctgcaag tttgtcatat
     8761 tcctcaaaca gctgtggaag atcttcctct gtgatcgcat acggttcact cggttctgca
     8821 actaccggct ccacggagat ctgtttgaaa ccaagatccg caagatgaag tacatctgct
     8881 gcaaaatcag gattgtagtg tgtgaatgta ccacgcacat aatatttgtc ctgatgtctg
     8941 ctctctgcaa atttctggaa ctttggaacg atcagatcat aacttcctgc ccctttgcgg
     9001 aacggacgca tcttatcatg aacttccttt cttccatcga tacttaagac cacatttgcc
     9061 atctctttgt tgcagaattc catgatctcg tcatttaaaa gcacaccatt tgtggtcagt
     9121 gtaaaacgga aattcttgtc atgcagcttt tcctgctctc ttccataggc aactaagtct
     9181 tttacgacct gccagttcat aagcggctcg ccgccaaaga aatccacctc aagatttcgt
     9241 ctgttacctg aattggcaat taagaaatcc agtgctttct ttccaacttc aaaggacatc
     9301 agtgcccttc ttccatggta ctctccctcc tcagcaaagc agtactgaca tgccaggttg
     9361 cagtcatgtg ctatatgcag gcagagtgcc ttgacaaccg tcgggcgttt tttgaaatcc
     9421 atgatatagt tttcgtaagt gtcctttgta aaaagtgact cctcatcgat caatgtctgg
     9481 acttcatcga ctgcttcctc cacttcctct ttgccgtatt ttccggacag tgcagatacg
     9541 atctcatccc ttgcatacga ttccggctgg ctctgatcga tcatctcaat gacatcataa
     9601 gtcacgtcat ccaccacatg aatcgctccg ctgtttacat ctaaaacaat atcatagccg
     9661 ttgttcttat actgatgaac cactataata tttcctctc
//
