LOCUS       gnlProkkaPOPHFAJL_7    15704 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|POPHFAJL_7.
ACCESSION   gnlProkkaPOPHFAJL_7
VERSION     gnlProkkaPOPHFAJL_7
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 21:41:32
            Original ID  :: gnl|Prokka|POPHFAJL_7
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15704
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15704
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[5452:5704]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5453..5704
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..15704
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15704
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(30..2339)
                     /locus_tag="ctg7_1"
                     /transl_table=11
                     /translation="MSMKVLTVLQFISIFTIYTGLFIAVPALLLHRRLKDEIFSVRFFF
                     YIVLGHFYLINLVLFLQLLHISGRFTLILGSALPVVISLVHTKRVSPKKIGHIIGNRTS
                     HVIRETLGIKLLLLEIVQWIGRKIKKLCGRMCGLIIRHFADGVLFVVFTATVLVMYGTN
                     MINTYGYCASDIPVHNYWINAMGQNDVFVAGIYPFGFHCVIYYIHTVTGIETYVLLRLF
                     YVVQVLYIHYALLAFLKACCRTSYCAWGAVFVYVLAAFFNRNTYSRYYSSLPQEFGMIF
                     ILPGIYFMYAFLKQRKIEVNQCKKERNAAGLKTWKCKSTRYLMGFIAGFGLTLIVHFYD
                     TMVAGLFCIGIAGGYLLRIFKKEYFFRVLATGLLSIFLAVLPMGIAFLQGTPLQGSLGW
                     GLNVINGSNNTGAEEEDEADIPGSEKEEINTNTQSVTDQSMTDSTDTAGSMTDQTMSEN
                     GVENAQMTEGTKVKTTRFGMLVEKIRFRITDITQNGLDYLWTGVHNVVMLQASVPWMLF
                     IFGCEGFCLIGGLLFTLIGKHDYGSMLMSAGFGLLLLMMFLSAWRFGLPHIMDASRCSI
                     YVAYMIPVAIGLGMDGMVTLVFGFFKRNIWMNLVSLMTSAALAATLVNGNQIRTPSILT
                     ALQSNAAITCLANIKRENEKYKYTICSANDELRMMEDYARHEETITFLRSMEGDAVNGN
                     LTLPTDRVYFFIEKIPLDYTVAYEGSGQLISEEGAKKPLPTAGDISVYEGENRWIVMSR
                     MYYWAQAFMEKIMAAG"
     CDS             complement(2354..3265)
                     /locus_tag="ctg7_2"
                     /transl_table=11
                     /translation="MTVAEKRFCIVLLINTAVAVLYVIGNSRIRQKEKNTDILMKGIMM
                     FLCPVVGPLFFLAGLVFNKVFFRQNVDLEDVIFSKERVKTHLRADEEREGNLVPIEEAL
                     AISDKDSLRTLVMNVVRGDVQNSLASISLALNSEDTETSHYAATVLRDALNDFRKRAQE
                     LYLQMKQEGVDAAEAACILIEYMHGVLIQEVFHEKEQQTYIDMMEEACNFLDEKYQEKL
                     QASYIEGLCVLLLKIKDFKRMKYWCDKSRELYPAELSTYTCYLKLYFTEGNKKHFFDEL
                     EKLKNSDIVIDRETLELIRIFS"
     CDS             complement(3262..5439)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score: 79.5;
                     E-value: 4.8e-24)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg7_3"
                     /sec_met_domain="RmlD_sub_bind (E-value: 1.2e-19, bitscore:
                     62.6, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNILLVGNAGNFMRLMINRLNKEGHRVFVLTEEPKKGYSLKKVFE
                     VYHFSYEDACVREVLESIMPQVVVFLGAYDHNFSWNRVENTAASYAAGLTNILMNYTAL
                     KKGRFVYLSSESVFGGGSAQFMTEDDPTGAYSKKGQAIAIGEDICKNYARMGNDVVILR
                     LDHLYGEIRKKEDTDTICADMCLEAVQTGEIIASQNEKIMLLHEADAVEFIYQIMVAKD
                     HKHTLYQLSSGEKMSRYELAQAVAAGMENEVSIVEEENKKYREVMLSGKRYDEEFGSRV
                     LHHAGTDVEKIAAYFSRHVSEFTDAGQKKGHLFRRLGSRTKEIITNLIPFMENLICFIP
                     FFMLNNRAVGSEYFQNIDFYLLYVLLFALVYGQQQATFSALLAVAGYCFRQMYHRSGFD
                     VMLDYNTYVWIAQLLILGLAVGYLRDQLRAMREEQRHEVSYLTKQLDDISDINVSNVRV
                     KEILANQIVNQNDSFGKLYEITSSLEQYEPCEVLFYAAEVLAKLMGSKDVAIYTVANRS
                     YARLFSATSEKARSLGNSINYSEMDAMYTVLAGKKVYINKNMDERYPLMANAIYSEDEM
                     QLILMIWGIPWERMTLGQANMLTVIGYLIQNAVVRANRYISALEQQRYIKGTNILEPEA
                     FLALVKAYLNARDKGLTQCALLSVDTKENDRDEVGKRLIKLLRQSDYVGELEGGKMYAL
                     LANTSAKDATMVKERFEKEGVSCQIQEDVFV"
     CDS             complement(5453..5704)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg7_4"
                     /sec_met_domain="PF05402 (E-value: 9.4e-15, bitscore: 46.9,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1.1e-10,
                     bitscore: 33.6, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEWYQLRQAAGAYWLLDMEQGEQYKKPFMLNECGAYIYRAYISG
                     MSEDEITQAFAKEYGLSFSCAQSDVGQFMMELRQQGII"
     CDS             complement(5745..6590)
                     /locus_tag="ctg7_5"
                     /transl_table=11
                     /translation="MSEIILRKYHGVGNDYLIFDPKKNDVVLNERLIRQLCRRNIGVGA
                     DGILYGPVMEDKKIKVRIFNPDGSEAEKSGNGIRIFSRYLKDAGYVKERQYYLTTKAGE
                     TLVTFLDDAGSCMRVDMGYAVFEAEQIPALGFEGEVVGESIFFCDNFYNATCVSMGNPN
                     CVIMLERVDREKALHLGPYVENAKYFTNRINMQLCQIVDEKNIQVEIYERGAGYTFASG
                     TGACAAAAASHRLGLVEDAVTVHMHGGDLFIEFEKDGRIFMTGPVVYIGKITVAEQFFA
                     "
     CDS             complement(6646..6969)
                     /locus_tag="ctg7_6"
                     /transl_table=11
                     /translation="MMMKDMIDKRNERERIARSIIKYWNVNYIPRTQADFGMQKQTAEA
                     ENAQDQTMDPNMQEDYNKATNAYSGKYGQEKDLDEVTKDQIDKILHEKAEHIHQLFENG
                     GVE"
     CDS             7111..7890
                     /locus_tag="ctg7_7"
                     /transl_table=11
                     /translation="MASYKVEICGVNTAKLPILKEEEKDALFARIKQGDTAARETYIKG
                     NLRLVLSVIKRFSGNHENVDDLFQIGCIGLIKSIDNFDPTIGVKFSTYAVPMIIGEIRR
                     YLRDNNSIRVSRSLRDTAYKAIHTKEILSKTENKEPTLDEIAAESGISKEDIVFALDAI
                     QSPLSLYDPVYTDGGDTLYVMDQISDKKNREENWIEELSLNDALDRLNERENYILKLRF
                     FEGKTQMEVADEIHISQAQVSRLEKSALKSIRHYLSL"
     CDS             complement(7887..9497)
                     /locus_tag="ctg7_8"
                     /transl_table=11
                     /translation="MVLEFLGAAHEVTGSCHYLSFGDKHILVDCGMEQGPDLYTNQEIP
                     VNAAMIDYVFVTHAHIDHSGLLPLLYNHGFRGKIYCTLATNELCNIMLKDSAHIQMFEA
                     EWRNRKAKRAGKPEVVPLYDMNDAMSVLSHFVPCDYQKKIKVCDGLEIRFVDAGHLLGS
                     SSIEMWVRDDDGTEVKLAFSGDIGPGNRPLIKDPEYIKDADYVIMESTYGDRKHNTPPD
                     FAIALAKVIKETLYERGGNLVVPAFSVGRTQEMLYFIRRIKSEHLLPEFENFEVYIDSP
                     LAVEATSIFNKSVEECFDEDARALVQQGINPIGFPGLKMAITSDESKMINFNDNPKVII
                     SASGMCEAGRIRHHLKHNLWRKDSTILFVGYQVPGTLGFSLLNGAKEVRLFGETIEVAA
                     RIENLPGISGHADVEQLTKWAAAFENKPKKVFVVHGEDKVTEQFADHLKDTLGYEAYAP
                     FPGDAFDLATGEQVREGSRERAEKKITEKSRASSNVFARLLAAGQRLLTVINKCEGMPN
                     KELGKFADQINALCNKWDR"
     CDS             complement(9625..10356)
                     /locus_tag="ctg7_9"
                     /transl_table=11
                     /translation="MYIKFAIPKIRTMIFPGIFRKKKDEVHYIGGAEVLPPPLAGEDEA
                     VCIEMLTSDESGQIARKRLIEHNLRLVVYIAKKFDNTGVGVEDLISIGTIGLIKAINTF
                     NSGKNIKLATYASRCIENEILMYLRRNSKTRMEVSIDEPLNVDWDGNELLLSDILGTDE
                     DVIYHDIETDVEHRLLKTAIGKLSGRERMIIELRFGLNSIDGEEKTQKEVADMLGISQS
                     YISRLEKKIMGRLKKEIVRLE"
     CDS             complement(10370..11125)
                     /locus_tag="ctg7_10"
                     /transl_table=11
                     /translation="MAILGCNCLLKRRIHPGRLFAVSLMFSLIHLFLVCFINNRILYFL
                     IAHFVLNTGMVFFCFGWEGKRSYLENWVVTYFMCVIQGGALEWLLEQHIFSQNEILQML
                     VAAAVVVTAVICFGERRVCGNHIYPAELKKGERYIRLRAYWDSGNQLTDPYTGQEISIL
                     SGSVAEKFFTKEKDLVRFVPYRSLGEKDGLIAVTNVDEMTVFQGKRAVKIPHAAIGTAD
                     KMLFDGKEYEMLLNASSIMPQGGKTENKN"
     CDS             complement(11450..12646)
                     /locus_tag="ctg7_11"
                     /transl_table=11
                     /translation="MLEIKTTEADTSAKIIVIGVGGAGNNAVNRMIDESIGGVEFIGVN
                     TDKQALALCKAPTLIQIGEKLTKGLGAGAQPEIGQKAAEESMEELSAAVKGADMVFVTC
                     GMGGGTGTGAAPVVAKIAKEQGILTVGVVTKPFKFEAKQRMLNALSGIDRLKESVDTLI
                     VIPNDKLLEIVDRRTTMPDALKKADEVLQQAVQGITDLINLPALINLDFADVSTVMKDK
                     GMAHIGIGNAKGDDKAIEAVKLAVASPLLETTINGASHVIINISGDISLMDANDAASYV
                     QDLAGDNANIIFGAKYDESMTDEATITVIATGLENAAAPKSKIMPDLRYGNTTNVTRPV
                     GTPGINRQAANLGASVQAHTQTQTAAPSFSGIQRPRQPESTVQPMDIKIPDFLKNSRK"
     CDS             complement(12763..13518)
                     /locus_tag="ctg7_12"
                     /transl_table=11
                     /translation="MRIKEQRKRKKRRRIGICIFLVVLMLFALAALIVVKVFTVQNVVV
                     EGNSLYSADQIKNMVLDDDYSWNSLYVDLKYRFVDVGEVPFVDTMEISLDDPHTLRISV
                     TEKGILGSFYIDTLGQYAYFDKDGFVVETSSDVIEGVPKITGVTCDSVVLYEKLPLEDT
                     KLLRNLLTLTQLLKKYELEPEEIHYDSAMQPQLTYGTIAVNVGSEDYLTQKIARLSAIM
                     PQLSGLSGILHLETWTPDTTDIVFDRADL"
     CDS             complement(13521..14639)
                     /locus_tag="ctg7_13"
                     /transl_table=11
                     /translation="MARRRKNEKRQKSIRYFDYSLLFLIIFLLCFGLIMLYSTSSYYGS
                     TRFNDAAYYVKRQMYASALGIVAMLFISRIPYKFWMQLSTLAYFVALVLCTAVIFVGTS
                     AKGQSRWLRIGPIQFQPSEIAKIAVIIFLATIIYKTPKRIGEIMSLLKIMLLISPVLAV
                     VAYNNLSTAIIILGIAVCMLFVASPKYLQFILMGIGVCLFGALFILLASYRAERVMIWL
                     HPEDYEKGYQTLQGLYAIGSGGLFGKGLGESMQKLGFIPEAQNDMIFSVICEELGLFGA
                     VCLILLYLLIIWRLMIIANNASDLYGALIVVGIMAHLSIQVLLNIAVVTNTIPNTGVSL
                     PFISYGGTSISILLAEMGLALSVSRGIKLEVA"
ORIGIN
        1 accatcacat tttcctttcc aaatccatct catcctgcag ccattatttt ttccataaat
       61 gcctgtgccc agtaatacat tcttgacatt acgatccatc ggttttcacc ttcataaacc
      121 gaaatatctc ctgctgttgg cagcggtttt tttgctcctt cttctgaaat gagctgtccg
      181 cttccctcat atgccacggt ataatcaagt ggtatcttct caataaagaa atatacgcgg
      241 tctgtcggca gcgtcagatt tccattgacc gcatctcctt ccatactccg taaaaatgta
      301 attgtttcct catgacgtgc ataatcttcc atcattcgca gttcatcatt cgcagaacag
      361 attgtatatt tatacttttc gttctcccgc tttatatttg ccagacaggt aatcgccgca
      421 ttcgactgca gtgccgtcaa tattgacggc gtacggatct gatttccatt gacaagtgtc
      481 gcagcaagtg ccgctgacgt catcagtgaa acaagattca tccagatatt ccgcttaaaa
      541 aatccaaaga ccaatgttac cataccgtcc attccaagtc cgatcgctac cggtatcata
      601 taagcgacgt agatactgca ccggcttgca tccatgatat gtggcagtcc aaaacgccat
      661 gcagaaagaa acatcatcaa aagcagcaga ccaaatcctg cggacatcag cattgatcca
      721 taatcatgtt ttccaatgag cgtaaacaat agtccaccga tcaggcagaa tccctcgcac
      781 ccaaaaataa acaacatcca tggcacgctt gcctgaagca ttacaacatt gtgcactcct
      841 gtccacagat aatccaatcc gttttgggta atatccgtaa tccggaaacg tatcttttcc
      901 accagcatac caaaccttgt tgtttttacc ttcgtccctt ctgtcatctg tgcattttcc
      961 acaccatttt ctgacattgt ctgatccgtc atgctcccgg cagtatccgt actatccgtc
     1021 atgctctgat ccgttacact ctgtgtattt gtatttattt cttccttttc actgccaggg
     1081 atatctgctt catcttcctc ctcagcaccc gtattattgc tgccattaat tacattgagt
     1141 ccccagccca gcgatccctg taaaggcgta ccctgtaaaa aggcaattcc catcggaagc
     1201 actgccaaga agatacttaa aagaccagtc gcaagaaccc tgaaaaaata ctcctttttg
     1261 aaaatacgca acaggtatcc tcctgcaata ccgatacaga acaaccctgc taccatagta
     1321 tcataaaaat gtacgatcag cgtaagtcca aatcctgcaa taaatcccat aagataacgg
     1381 gtacttttgc atttccaggt ttttaatccg gcagcgtttc tttccttttt gcattgattc
     1441 acttctatct tccgctgttt taaaaaggca tacataaaat aaatgccggg caggataaat
     1501 atcatgccaa attcctgagg cagcgaactg taataacgcg agtaagtatt cctgttaaaa
     1561 aatgcagcaa gtacatagac aaatacagct ccccatgcgc aatacgatgt cctgcagcac
     1621 gctttcaaaa atgccagaag tgcataatgg atatataaga cctgcaccac ataaaaaagc
     1681 cggagcagca catacgtttc aatccctgtt accgtatgga tataataaat tacgcagtgg
     1741 aatccaaatg gataaattcc agctacaaac acatcattct gccccatcgc attgatccag
     1801 taattgtgta ccggtatatc ggatgcacaa taaccgtatg tatttatcat attggttcca
     1861 tacattacca gaaccgttgc agtaaataca acaaacagca ctccatctgc aaaatgcctg
     1921 atgatcagcc cacacattct gccacacagt ttcttaattt ttctgccaat ccactgtaca
     1981 atctccagaa gaagtaattt aatgccaagc gtctcccgga tcacatggga tgttctgttt
     2041 cctatgatat gtccgatttt tttaggtgaa actcttttcg tatgtaccaa ggatataacg
     2101 actggaagtg cactgcccaa aatcagcgta aatctgcctg aaatatgaag cagctgaaga
     2161 aataatacca gattgatcag atagaaatga cctaatacga tataaaagaa aaaccgtaca
     2221 ctaaatattt catcttttaa cctgcggtgc agaagcagtg ccggaactgc gataaaaagt
     2281 cccgtataaa ttgtgaaaat gctgataaac tgtaacacag tcaggacttt catcgacact
     2341 gccatcacct cctttagcta aaaatacgaa ttaattccaa tgtttccctg tcgatcacaa
     2401 tatctgaatt ttttaatttt tccaattcat caaaaaaatg ttttttgttt ccctctgtaa
     2461 aataaagttt taaataacag gtataggtag ataattctgc cggatagagt tccctgctct
     2521 tatcgcacca gtatttcatg cgcttaaaat cctttatctt aagaagcaga acgcaaagtc
     2581 cctcaatata ggaagcctgc agtttctcct ggtatttttc atccagaaaa ttacatgcct
     2641 cctccatcat atcgatgtag gtctgctgtt ccttttcatg aaacacctcc tggatcaata
     2701 ccccatgcat atactcaatc aggatacagg ctgcttctgc cgcatcaact ccctcctgtt
     2761 tcatctgaag gtaaagttcc tgtgcacgct ttctgaaatc attcaatgca tcccttaata
     2821 ctgtagcggc ataatgtgat gtttccgtgt cctcactgtt taacgcaagc gagatggatg
     2881 ccagagaatt ctgtacatcc ccacggacca cattcatgac cagcgttctt aaactgtctt
     2941 tgtcgctgat cgcaagtgcc tcctcaatcg gtactaaatt tccttccctt tcctcatctg
     3001 cccgaagatg tgtctttaca cgctccttgc tgaaaataac atcctcaaga tccacgttct
     3061 gccggaaaaa aaccttgtta aacaccagtc ccgccaaaaa aaacaacggt cccactaccg
     3121 ggcagagaaa catcatgatc cccttcatca gaatatctgt atttttttct ttctgcctga
     3181 tcctgctgtt tcctatcaca tataaaacag caacagccgt attgatcaga agaacgatac
     3241 aaaatctctt ttctgcaacc gtcatacaaa tacatcctcc tgtatctggc aggacacacc
     3301 ctctttttca aatctttctt ttaccatggt tgcatctttt gcactggtat ttgcaagaag
     3361 cgcatacatt tttccacctt caagttcacc gacataatcg ctttgtctaa ggagtttgat
     3421 aagccttttc ccgacctcat cacggtcatt ttcctttgta tccacggaaa gcagtgcaca
     3481 ctgtgtcaat cctttatcac gcgcatttaa atacgccttt acaagtgcta aaaaggcttc
     3541 cggttctaat atattcgttc cttttatgta acgctgctgc tctaaggcag aaatataacg
     3601 gtttgcacgc accaccgcat tctgaatcag ataaccgata accgtcagca tattcgcctg
     3661 tcctaacgtc atccgctccc acggaattcc ccagatcatc agaatcagct gcatctcatc
     3721 ttccgaataa atggcatttg ccataagcgg atatctttca tccatatttt tattaatata
     3781 aactttcttc ccggcaagca ccgtatacat ggcatccatc tcgctgtaat tgattgaatt
     3841 accgaggctg cgtgctttct ccgatgttgc agaaaaaaga cgtgcatagg aacggtttgc
     3901 caccgtatag attgccacat ctttgcttcc catcagtttt gcaagtactt ccgccgcata
     3961 aaaaagtacc tcacagggtt catactgctc taaactggat gtgatctcat ataattttcc
     4021 aaaactgtca ttctggttta cgatctggtt tgcgagaatt tcttttaccc tgacattgct
     4081 gacattgata tccgaaatat catctaactg cttggttaag tatgatactt catgccgctg
     4141 ttcctccctc attgcacgaa gctggtctct cagatatccc actgccagac ctaagatcaa
     4201 aagctgtgcg atccagacat aggtattata gtcaagcata acatcaaatc cgcttctgtg
     4261 gtacatctgc cggaaacagt accctgccac ggcaagcaat gcagaaaatg ttgcctgctg
     4321 ctgcccgtat acaagtgcaa acaacagcac atacagaaga taaaaatcaa tattctgaaa
     4381 gtattcactt ccgactgcac ggttattcaa catgaaaaac ggaataaaac aaatcaggtt
     4441 ttccataaaa ggaatcagat tcgttatgat ttcctttgtc ctgctgccta atcttcgaaa
     4501 cagatgtccc tttttctgcc ctgcatctgt aaattcagat acatgtctgc tgaaataagc
     4561 cgcaatcttt tccacatctg ttcctgcatg atgaagcaca cggcttccaa attcttcatc
     4621 gtatctttta ccggaaagca taacttcccg gtattttttg ttttcctctt ctacgatact
     4681 gacctcattc tccattcctg cggcaacagc ctgggcaagc tcataccgtg acattttctc
     4741 cccggaagat aactgataga gggtatgttt atggtccttt gccaccatta tctggtagat
     4801 aaactccacc gcatccgcct catgcagaag cattattttt tcattctgcg acgcaatgat
     4861 ctctccggtc tggactgctt cgaggcacat atccgcacag atcgtatctg tatcctcttt
     4921 ctttcgtatt tccccataca aatgatcgag gcggagaatc acaacatcat tccccatcct
     4981 tgcataattt ttacagatat cttctccgat agcgatcgcc tggcctttct tgctgtatgc
     5041 cccggtagga tcatcctctg tcataaactg tgcgcttcca ccgccaaaaa cactctccga
     5101 agaaagatag acaaacctgc ctttctttaa agcggtataa ttcatcagta tattcgtaag
     5161 tcccgctgca taggacgccg ctgtgttttc caccctgttc caggaaaaat tatggtcata
     5221 tgcccccaga aaaactacta cctgtggcat aatactctct aatacctccc gcacacaggc
     5281 atcctcatac gaaaaatgat acacttcaaa tactttcttc aggctgtatc ccttctttgg
     5341 ttcttctgtc agcacaaaga ccctgtgtcc ttccttattc agtctgttga tcataagccg
     5401 cataaaattg ccggcattcc caactagcaa tatattcata cctgctccat tctcaaataa
     5461 ttccctgttg tcttaactcc atcataaact gccctacgtc gctttgtgcg caggagaatg
     5521 acaatccata ttcttttgca aatgcctgcg tgatctcatc ctcagacatt cctgaaatat
     5581 acgcacgata tatatatgca ccgcactcgt tcaacatgaa tggcttttta tattgttccc
     5641 cctgctccat atccaaaagc cagtatgccc ccgctgcctg gcgtaattga taccattctt
     5701 tcattgtaac ttatttcccc tcttttcgcc actttcgttt tctgtcaggc aaaaaactgt
     5761 tctgccacag taatctttcc tatatatacg accggtcctg tcatgaaaat tcttccatcc
     5821 ttttcaaatt cgataaaaag atctccaccg tgcatatgta cggtcactgc atcttcgact
     5881 aatcccagac ggtgagaagc cgctgctgcc gcacaggctc cggtgccgga agcaaatgta
     5941 taccccgccc cacgttcata aatttcaacc tgtatatttt tttcatctac gatctgacaa
     6001 agctgcatat tgatacggtt tgtaaaatat tttgcatttt ccacatatgg tcctaaatgc
     6061 agtgctttct cacgatctac cctctcaagc ataataacac aatttggatt tcccatggat
     6121 acacaggtcg cattataaaa attgtcgcag aaaaatatcg attctcctac aacttctccc
     6181 tcaaatccaa gtgccgggat ctgttctgcc tcaaagaccg catatcccat atccacacgc
     6241 atacagcttc cagcatcatc caaaaatgtt accagtgttt cccccgcttt cgtggtcaga
     6301 taatattgcc tttcttttac atatccggca tcttttaaat atcttgaaaa aatccggatg
     6361 ccattgccgc ttttttcagc ttcacttcca tccggattaa aaattcgtac tttaattttt
     6421 ttatcttcca taaccggtcc gtacaaaatt ccatctgcac cgacaccaat attgcgtcta
     6481 caaagctgcc ttatcaatct ctcatttaaa actacatcat ttttcttcgg atcaaagatc
     6541 agataatcat tgccaactcc atggtatttg cgaagtatga tctcagacat cttgattcct
     6601 ctgccatttt ccttgtgata tcatatgcag aataacagga aatggttact ctactccccc
     6661 attttcaaac aactggtgaa tatgttccgc cttctcgtgg aggatcttgt caatctgatc
     6721 tttcgtcact tcgtctaagt ctttctcctg accatattta cccgaatatg cgttcgttgc
     6781 tttattgtag tcttcctgca tatttggatc catagtctgg tcttgcgcat tttctgcctc
     6841 cgcagtctgc ttctgcatcc cgaaatcagc ctgcgttctc ggaatatagt tcacattcca
     6901 gtacttgata atacttcttg cgatacgttc ccgttcattt ctcttatcga tcatgtcttt
     6961 catcatcact gcaccacact ctgttctgat ttttgatacc tttttatttt agcacgaaac
     7021 ccattggaaa aaaagttaat ttctgaataa aattcatcct tttgaagcat gctctttatg
     7081 gtaaagataa aattccggag gataaacagc atggcttctt ataaagtaga aatctgcggc
     7141 gtcaacaccg caaaactccc cattttgaaa gaagaggaaa aagatgctct gtttgcacgg
     7201 atcaaacagg gagataccgc cgccagagaa acttatatca aaggcaatct caggctggta
     7261 ttaagtgtca tcaaacgttt ttccggcaat cacgaaaatg tagatgatct gtttcagatc
     7321 ggctgtatcg gcctgatcaa gtccatcgac aacttcgatc cgacgatcgg ggttaagttt
     7381 tccacttacg cagttcccat gattataggt gagataagac gttacctgcg cgacaataac
     7441 tctatccgcg tcagccgttc cctgcgcgac actgcctaca aggcaatcca caccaaagaa
     7501 atactctcaa agacggaaaa caaagagccg actctcgacg aaattgccgc cgaatccggc
     7561 atttctaaag aggacatcgt tttcgccctc gatgccatcc agagtcctct cagtctttat
     7621 gacccggtct acaccgatgg cggtgacaca ctctatgtca tggaccagat cagtgacaag
     7681 aaaaaccggg aagaaaactg gattgaagag ctgtccctaa acgatgctct cgaccggtta
     7741 aacgaacgtg aaaattatat cttaaaactt cgcttttttg aaggaaaaac gcagatggaa
     7801 gtggctgacg agatccatat ctcccaggct caggtcagcc gcttagaaaa atctgcgtta
     7861 aaatccattc gtcattatct gtcgctctaa cgatcccatt tattgcacag agcattgatc
     7921 tgatctgcaa atttgccaag ttctttgttt ggcattccct cacacttatt gataaccgta
     7981 agaagtctct gacctgcagc aagcagtctt gcaaatacat tgctcgatgc acggctcttc
     8041 tctgttatct tcttctctgc ccgttctctg gatccttcgc gtacctgctc gccggttgca
     8101 aggtcaaatg catctcccgg gaacggcgca taggcctcat accccaaagt atctttcaaa
     8161 tgatccgcga actgctccgt aactttgtct tccccgtgta ccacaaatac ttttttcggc
     8221 ttattttcga atgctgccgc ccattttgtc agttgttcca catctgcgtg gccgctgata
     8281 cccggcaggt tctcgattct tgccgcaacc tcgattgtct caccaaagag ccttacctct
     8341 tttgcaccat ttaagagtga aaagccaagt gttcccggca cctgatatcc cacgaataag
     8401 atcgtggaat cttttctcca cagattatgt ttcaaatggt ggcggatacg tcccgcctca
     8461 cacattccgg atgcagagat aataactttg ggattatcat taaagttgat catttttgac
     8521 tcatcacttg tgatcgccat tttaagtccc ggaaatccga tcggattaat cccctgctgc
     8581 acaagtgctc tcgcatcttc gtcaaaacat tcttccacac tcttgttaaa aatgcttgtc
     8641 gcttcaaccg ctaacggact gtctatgtat acctcaaaat tttcaaattc cggcagcaga
     8701 tgctcactct tgatcctgcg gataaaataa agcatctcct gtgttctgcc cacggaaaat
     8761 gcaggaacga ccagattacc gccgcgttca tacaatgttt ctttgatcac ttttgccagg
     8821 gcgatcgcga aatccggagg tgtgttgtgt tttctgtcac cataggttga ctccatgatc
     8881 acataatcgg catctttgat gtattccgga tctttgatga gcggacggtt acctggtccg
     8941 atatcaccgg aaaatgccag ttttacctct gtaccatcat catccctcac ccacatttca
     9001 atgcttgagg atccaagcag atgacctgca tctacaaaac ggatctcaag tccgtcacag
     9061 actttgatct ttttctgata atcacacggc acaaaatggc tcagtacgct catcgcatca
     9121 ttcatatcat aaagaggcac cacttccggt tttccggccc gttttgcctt acgattgcgc
     9181 cattctgcct cgaacatctg gatatgtgca ctgtctttga gcataatgtt gcagagttca
     9241 ttggtcgcta aggtacagta tattttgccg cggaaaccat gattgtataa aagcggcaat
     9301 aatccggaat gatcaatatg tgcatgcgtc acaaatacat aatcgatcat cgctgcattg
     9361 accggaatct cctgatttgt gtacagatcc ggcccctgtt ccataccaca gtccaccagt
     9421 atatgcttat ctccaaagga tagataatga caactgcctg ttacctcatg tgctgcgcct
     9481 aaaaattcca ataccatatg aagtccccca ttctgtctgc ttttctttca ttatactatt
     9541 tttcagctat atgcacaata ttttttcata ttttatatat tttttaacta ttttgtcatt
     9601 ttaccagaca aaaacagaga gactttactc aagacgcacg atttcttttt tcagtcttcc
     9661 catgatcttt ttttccagtc tggatatgta ggactgggaa ataccaagca tatccgcaac
     9721 ctctttctgg gttttttcct ctccatcgat ggaatttaac ccaaaccgca gttcaatgat
     9781 catccgttcc ctgccagata gttttccaat cgctgtctta agcagccgat gttccacatc
     9841 cgtttcaatg tcgtgataga tcacgtcctc atcggttcct aagatatccg aaagtaacag
     9901 ctcatttccg tcccagtcca cgtttaaagg ctcatcaata gacacttcca ttctcgtttt
     9961 gctgtttcgc cgcagataca tcagaatttc attttcaatg catctcgaag cgtaggtcgc
    10021 aagtttgata tttttcccgg aattaaatgt gttgattgct ttgatcagac cgatcgtacc
    10081 gatagaaatc agatcctcca ccccgacgcc ggtattatca aatttttttg caatatacac
    10141 cacaagccgc aagttatgtt caatcagccg ttttcttgca atctgtccgc tttcatcact
    10201 ggtaagcatc tctatgcata ccgcctcatc ttcaccggca agcggcggcg gaagtacctc
    10261 tgcgcctccg atataatgca cctcatcctt tttctttcga aaaataccgg gaaatatcat
    10321 cgttcttatc tttggtatcg caaattttat gtacattttc aattccacct taattcttat
    10381 tttctgtctt gccgccttgt ggcataatgc tcgaagcatt taagagcatt tcatattcct
    10441 taccgtcaaa cagcatctta tctgcggttc caatcgctgc atgtgggatt tttaccgcac
    10501 gttttccctg aaaaacagtc atttcatcca catttgttac cgcgatcagt ccatcctttt
    10561 cccccagtga tcgatatggc acaaaacgaa ccagatcctt ttcttttgta aagaattttt
    10621 ccgccacaga tcctgataga atactgatct cctgtcctgt gtacggatcc gtcagctgat
    10681 tcccgctatc ccagtatgca cgcagtctga tatacctttc tccttttttt aactctgcag
    10741 gataaatatg atttccacaa acgcgccttt caccaaaaca gatcactgcc gtaacaacta
    10801 ccgctgccgc aacaagcatc tgtaaaattt cattttgcga aaatatatgc tgttctaaaa
    10861 gccactcaag cgcacctccc tgtatcacgc acataaaata ggtcacaacc cagttttcta
    10921 aataactgcg ttttccttcc caaccaaaac aaaaaaatac catccctgtg tttaaaacaa
    10981 aatgtgcgat caaaaaatac aggatcctgt tattgataaa gcacaccaga aacagatgaa
    11041 tcagcgaaaa catcagcgat accgcaaaca gccgcccggg atgtatcctc cgtttcagca
    11101 ggcagttgca tccaagtatt gccatatagt ccataaacag attttcaagc aggaacacat
    11161 ctgcataaaa tacatagatc tcgtctcacc ccttttctcc agactctttc gtatctttac
    11221 tgttattata aaacagtaca actttacttt ttgtcaaaac aggtactcca aatcccgcaa
    11281 atcatccctt attttcgaca agcgttgttc ttttctatat ataaaaagag atttatgtgt
    11341 tttctcttca aacacataaa tctcttttca gatgtataaa ctgctgctgc agcccgcgta
    11401 ctttgcaggc atatctgttg ttatgttttc taatatttta tctcagatat tattttcttg
    11461 aatttttaag gaaatccgga attttaatat ccattggctg tactgtgctc tcaggctgac
    11521 gcggtctctg aataccagaa aatgatggtg cagccgtctg tgtctgcgta tgtgcctgta
    11581 cacttgcacc aagatttgcc gcctgtctgt tgatgccagg tgttccaacc ggtcttgtaa
    11641 cgtttgttgt atttccatag cggagatccg gcataatctt gctcttcggt gctgccgcat
    11701 tctcaagtcc tgttgcgata actgtgatcg tagcttcatc tgtcatagac tcatcatact
    11761 tcgcaccaaa aataatgttt gcattatcac ctgcaagatc ctgaacatag cttgctgcat
    11821 cgttcgcatc catcagggaa atatcaccgg aaatattgat aataacatgg gatgcaccat
    11881 tgatcgtggt ctctaacagc ggactcgcaa ctgcaagttt gacagcttcg attgctttgt
    11941 catctccctt ggcattaccg ataccgatat gtgccatacc cttgtccttc atgacagtgg
    12001 aaacatcagc aaagtcaaga ttgatcagtg ccggcagatt gataaggtct gtaattccct
    12061 gaacagcctg ctgtaacact tcatctgcct tctttaaggc atccggcatg gtcgtacgtc
    12121 tgtcaacgat ctccagaagc ttatcattcg ggatcacgat cagtgtatca acgctctctt
    12181 ttaaacggtc aataccggaa agtgcattta acatacgctg ttttgcttca aatttgaatg
    12241 gttttgtcac aacgccgacc gttaagattc cctgctcttt tgcaatcttt gcaacaaccg
    12301 gtgctgcacc tgttccggtt ccgccaccca taccacaggt tacgaaaacc atatccgcgc
    12361 ccttcactgc tgcagataat tcttccatgc tttcctcagc ggctttctga ccgatttccg
    12421 gctgtgctcc tgctccaagt ccttttgtca gcttttcacc gatctggatc agtgtcggtg
    12481 ctttacagag tgccaacgcc tgtttatctg tatttactcc gataaactcg actcccccga
    12541 tactctcatc aatcattcta tttacagcat tattaccagc tcctcctact ccgatcacga
    12601 tgatctttgc actggtatcc gcttctgttg tcttaatctc cagcaaggta gttcctcctt
    12661 catttagctt aaaaaattac agctaaaaaa ctcatataat ctataatata atttttctta
    12721 caattaatca actgattttt caaaaaagat tacacttttt ttttacaaat ctgcacggtc
    12781 aaacacaata tctgtcgtat ccggcgtcca tgtctctaaa tgcagtatac cggagagtcc
    12841 cgacaactgt ggcataattg cggaaagtct cgcaattttc tgtgtcagat aatcttctga
    12901 accaacattg accgcaatcg ttccgtaagt gagctgtggc tgcattgcac tgtcatagtg
    12961 gatttcttcc ggttcaagtt catatttttt cagtagttgt gtcagtgtca acagatttct
    13021 cagcagtttt gtatcctcaa gcggcagttt ttcgtataaa accacactat cacaggtaac
    13081 tcccgtgatc tttggcactc cttcgattac atccgacgaa gtttccacaa caaatccgtc
    13141 tttatcaaag tacgcatatt gtccaagcgt atcaatataa aaactgccca gaataccttt
    13201 ttctgtaacc gaaatccgca atgtatgcgg atcatccagc gaaatttcca tcgtatccac
    13261 aaacggtact tccccgacat ccacaaaccg gtatttcaga tctacataca gactgttcca
    13321 cgaataatca tcgtccagca ccatattttt gatctggtcg gcagaataaa gactgtttcc
    13381 ttccacaact acattctgga ctgtaaatac ctttaccaca ataagtgccg caagtgcaaa
    13441 caacatcaga actaccagaa agatacagat cccgattctt cttctttttt ttctttttct
    13501 ctgttctttg atcctcataa tcaggcaacc tctaatttaa ttcccctcga tacagaaagt
    13561 gccagcccca tctcagccag caaaatcgat atggatgttc ctccataact gataaacggc
    13621 agtgatactc ccgtattcgg tattgtattt gttacaaccg caatattaag cagtacctga
    13681 atggacaaat gtgccataat accaactacg atcaatgcgc catacagatc ggatgcattg
    13741 tttgcaatga tcatcagacg ccagataata agcagataca aaagtatcag acagactgca
    13801 ccaaaaagtc caagttcttc acagataacc gaaaagatca tatcattttg tgcctccggg
    13861 ataaatccca gtttctgcat gctctctcct aacccttttc cgaaaaggcc tcccgaaccg
    13921 atcgcatata atccctgcag cgtctgatac cctttttcat aatcctccgg gtgcagccag
    13981 atcataacac gttccgcacg gtaagacgcc agcagaataa acagagcacc aaaaaggcat
    14041 actcctattc ccattaaaat aaactgtaaa tatttcggac tcgcaacaaa taacatacag
    14101 acagcaattc caaggataat gatcgccgta cttaagttat tatacgcaac cactgccaaa
    14161 accggtgaaa tcaaaagcat gatcttaagc agactcataa tttccccaat gcgtttaggc
    14221 gttttataga tgatcgtcgc aaggaaaatg ataaccgcaa tttttgcgat ctcagatggc
    14281 tggaactgga tcggtccgat cctgagccat ctcgactgtc cctttgcact tgttccgaca
    14341 aaaataaccg ctgtacaaag taccagcgcc acaaaatacg caagcgttga aagctgcatc
    14401 cagaacttat atgggattct tgaaataaaa agcattgcca ctattccaag tgcacttgca
    14461 tacatttgtc tttttacata atatgctgca tcgttaaatc ttgttgagcc atagtaggaa
    14521 ctggtactat ataacataat cagtccgaaa cataacaaaa atataatcag aaataacagg
    14581 ctgtaatcaa aataccggat cgatttttgt cttttttcat ttttccgtct tcttgccata
    14641 atttttcctc atttacacaa aacctgtctg atcaagcacc acaaccgttt tattccggca
    14701 gttccatgac atattgccgg aacagttctc cccgctgtgt ataatcctta aaatctcccc
    14761 agctcgcaca tgccggtgaa agcaatactg cttccccggg ctttgccagc ctataacaga
    14821 tatttaccgc ttcatttaat gtatcacagc atacaatatt ctcaaaacca tgtttccttg
    14881 cgcagactgc gatcttatct tttgtctgtc cgatcagtaa tagacatttt actttcccat
    14941 caaagctctc aatccacgca tcaaattcaa gatttttatc ataaccgccg ccgatcagca
    15001 gtgtcttacg attcattgaa ccgatcccgc ggattgccgc atccggattt gtcgccttag
    15061 aatcgttata gtacaaaaca ccatgcagat ctctcacaaa ctcaatgcgg tgttttacac
    15121 cccaaaactc ttttagtaca cgctgcacaa catctatcgg tgctcccata caaagtgcag
    15181 tgccggaagc tgccataaca ttttcataat tatgtatgcc cagaagtttt aattcaccga
    15241 catcaatcag gcgctgccgt tctgtttctt ttccagcgat ccagatcgta ttttcctgca
    15301 gataaattcc ctcttccaat ggtcttttac tgctgaaaaa caaaacgttt acttttaatg
    15361 tttcggcaaa tttccgaagt atttcatcct catagttgag cacacaggta tcttcctttg
    15421 tctgacactt tgtaatgctc tcctttgcac ggatatacgc ctccatcgtg tgatgtctgt
    15481 caagatgatc cggcgtaata tttaaaattg cagaaacaga cggatgaaat gtttccatcg
    15541 tttctaactg gaaactgctg atctctgtca ctgtgacggt ctgctctgta gttttctcca
    15601 caattgaagt ataaggaata ccaatatttc caaccacaaa gacttccgga taacattttt
    15661 ttaagatttc tcccaccagt gtcgtcgttg ttgtcttacc attt
//
