LOCUS       c00010_gnlPro..        16245 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NHCOBFAG_10.
ACCESSION   c00010_gnlPro..
VERSION     c00010_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 23:04:12
            Original ID  :: gnl|Prokka|NHCOBFAG_10
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16245
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16245
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3252:6245]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3253..6245
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..16245
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16245
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(489..1676)
                     /locus_tag="ctg10_1"
                     /transl_table=11
                     /translation="MKKKIFILLLCVVLIATCILCGVTGIFGNDSQNSPKPQTPDTAVT
                     ENMTFPSKVDSLALKVGESKLIELSSEKAKSVTKWTSSDSKIVTVDDGGRVDALKEGTA
                     LISAISKDKSKSEFQVTVAKSTTKKQQSYSTCTTANLDKLENNKRNTAKNLYAIKVNRT
                     ANCVTVYTYDEKGKYTIPIRAMICSTGLDNSTITGDYTIGIKSEWLSLVGDVFGRYISG
                     ISGDYLFHSVPYYSMSEEDLELEEFNKLGEQASQGCVRLAVSDAKWVYDNCPTGTNVSI
                     YDDAENAGPLGKPDAIKITDFTNKWDPTDSNKKCPYAKATPIISGANDYTIKSGGEFYA
                     LAGVTAVDTCGNDITSNIEVFGNVVTTRKGKYKVTYSVTDVLKRTSSVTITVTVQ"
     CDS             1853..2377
                     /locus_tag="ctg10_2"
                     /transl_table=11
                     /translation="MAHPIKHFRTITRHRHKVIANCARAGILRQGLIHDLSKYSPTEFI
                     PGAKYFQGTRSPNEKERELYGYSQAWMHHKGRNRHHYEYWNDYNPKTKQIENVEMPVKY
                     VIEMFCDRVAASKIYNGKNYTDGAPFTYFCRIRGKHRMHPNTEALLEKLLVMLRDEGEE
                     KTFAYIRSMKK"
     CDS             2495..2986
                     /locus_tag="ctg10_3"
                     /transl_table=11
                     /translation="MKTDRVITAMIEYFGSDKKRIHHFLKVYSFAKTIGESENLLPDDQ
                     ELLEISAIVHDIGIKVSEEKYNSSAGKYQELEGPHEAEKLLAALGYEKTFIDKVCYLVG
                     HHHTYGNIDTLPYRILVESDFLVNLYEDDSSRSAAEQAYDKIFRTNTGKNLLKIMFLIP
                     "
     CDS             3253..5490
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg10_4"
                     /sec_met_domain="Gly_radical (E-value: 6.1e-41, bitscore:
                     131.3, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 1.6e-271, bitscore:
                     893.8, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MREEWTNFAGGKWESDIDVRDFIQKNYTPYDGDQSFLEGPTEATD
                     KLWGELKELQKEERAKGGVLDMETEVVSGITAYGAAYLDKDLEKVVGLQTDKPLKRAFM
                     PYGGIKMAEQSCQMYGYTPSPKLHEIFTKYHKTHNQGVFDIYTPEMKLARHNKILTGLP
                     DTYGRGRIVGDYRRVALYGIDRLIEGKKEDFAETNRQGMRRGDFQLREEIADQIRALND
                     MKEMALSYGFDISQPAKNAAEAVQWLYFGYLAAIKTQNGAAMSVGRVSTFLDIYIERDL
                     ENGTLTESQAQELVDHFVMKCRMVKFARIESYNQLFSGDPVWATLEVAGLGIDGRSMVT
                     KNDYRFLHTLENMGPSPEPNLTVLYSSRLPENFKKYAAHISVTTSSIQYENDDVMRPVW
                     GDDYSICCCVSATQTGKEIQFFGARANLAKCLLYAINGGIDEKTKMQVGPEYTPITSEY
                     LDYDEVIKKYDTMMDWLAHLYVGTLNMIHYMHDKYYYEAAEMALIDTDVRRTFATGIAG
                     FSHVVDSLSAIKYAKVKVIRDEDGVAVDFETEGDFPRYGNNDERADKIAVDLLKTFMAK
                     LKYCHTYRDSEPTTSILTITSNVVYGKATGSLPDGRKAGEPLSPGANPSYGAEQNGLLA
                     SLNSVAKLPYEYALDGISNTQTINPGALGHNDDERVDNLVNVMDGYFDQGAHHLNVNVF
                     GTEKLIDAMEHPEKEEYANFTIRVSGYAVKFIDLTREQQLDVIARTCHDRM"
     CDS             5490..6245
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 76.2;
                     E-value: 1e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg10_5"
                     /sec_met_domain="Radical_SAM (E-value: 4.2e-30, bitscore:
                     97.2, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDNAVKGFVHSIETFGSVDGPGVRFVIFLSGCAMRCQFCHNPDT
                     WKHDENTVEYTADELLNKALAYRPYWKNKGGITVSGGEPLLQIDFLLDLFKKAKKQGVN
                     TCIDTSANPFTTKEPFYSKWKELMEYTDLLLLDIKHIDNEQHKILTGQPNTNILEMARQ
                     LSDMGKPVWIRHVLVPERNDKDEYLFRLADFIRSLRNVERVEVLPYHTLGVYKWKALGY
                     DYPLEGINPPTKERVKNAEMILNGEKTRD"
     CDS             6594..8447
                     /locus_tag="ctg10_6"
                     /transl_table=11
                     /translation="MKSESIKKFGCVLLSAIMLSGISVCAVSAEEKSTEIHIVHTNDIH
                     GYYKSTSGGQIGFDAVKTIADKENADLILDAGDTFHGQSFATVEEGKSIAELMDAVGYD
                     AMTPGNHDWSYSADRLRELDRESSFTILASNVADTNGNRYFDNNFYIKNVTADDGTKVR
                     VGVFGVIDEDFYTSTSAKNVENVRFENSAETATAYANFLRDDENCDIILALTHNANPEK
                     FIAETSGIDAVIAGHQHILIDKYCTDSDGKSVKLVEANCFFKNVGVLTLTYSNEKGVTD
                     AVEKTYSSADTQGMSDEKIASDISAIEKREQSVLSEVIGESSREYAYSWEELRTSEQEI
                     GRIVTAAYLDFTGADVAMENAGGIRSGIPEGNVTYSDLISISPYGNVLVEKELTGQQII
                     DILEFSVDLMKKNNAVYDLQKQAIKDGEDPYQYSWPDNSGSVMQFSGLSAVYDYSKPYG
                     GRVSDVKIGGKAIDTLKTYRVVSNNYAFDSSDYGDVASLTTVKEYTTCEQILRDYISNG
                     DFEKAAANANLVEKSSPSEEPTATQEQTVQTAPTGEPATVGTTSVNPTSATGGAATSDS
                     TPSQPDKNGSVQTGVTATAVMMLVVILGGVLFALAERKKRI"
     CDS             8580..8798
                     /locus_tag="ctg10_7"
                     /transl_table=11
                     /translation="MDKNKKLFYTIIGAISALAAATAAFLALKKHRCAEQKLIEEIDDI
                     VSEKEPEETAKEEPQAEVTADELAEEE"
     CDS             complement(9019..10170)
                     /locus_tag="ctg10_8"
                     /transl_table=11
                     /translation="METLIIGKPKIEKLANRARLCSKISENGKPSYILWFDVDAKYADY
                     LTESADAFVVALLPYAMNNSLNISAEAKMSKQLCFQLNEIFIPVLTKNSKLFNKISISA
                     KELTQENYCCKNASATGFSRGVDSFDTICSLSENRTEKLSHLTFFNVGSHRSTANYTPE
                     QSAELYENRLEIAKKSAKIFDMPLIDINSNLGEHLTLPYVKVHHYCSFSAVLCMQKFFK
                     NYYYASGYPISSFSIKQCDTGSAHYEAFTASMLSTESTDFYITGLEKTRLEKVDFISKF
                     PITYDNLNVCYYGENNCGHCEKCVRTQFELMALGKLELYKNVFDIPKFYRDKNKYMDYV
                     LKHQNKDYYAEILSLMKKKGFKLTPIQKIKKAVYAIYLKFREN"
     CDS             complement(10186..11370)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) UDPG_MGDP_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) UDPG_MGDP_dh"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_9"
                     /sec_met_domain="UDPG_MGDP_dh_N (E-value: 3.3e-37,
                     bitscore: 119.8, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="UDPG_MGDP_dh (E-value: 1e-28, bitscore:
                     91.4, seeds: 679, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIAIAGTGYVGLSNAVLLSQKHEVTAVDVVESKVRLINEKKSPI
                     ADREIEEYLADKKLNLVATVDAKSAYKNADFVIISTPTNYDDERHFFDTSSVEAVIELV
                     IECNPNAVIVIKSTIPVGYTKSVIEKYKYTKILFSPEFLREGKALYDNLYPSRIIVGVD
                     MENEELKKSAETFATALADCAIKENIDTLFMDYTEAEAVKLFANTYLAMRVSFFNELDT
                     YAEMKNLNTKSIIDGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLKANFSDVPNDIISA
                     VVTSNKTRKEFITSQIMNKNPKAVGIYRLTMKSNSDNFRQSSIQSVMELLKNNGIELII
                     YEPTLKVDLFEGFGVENDFEKFVTKSDVIVANRYSSVLDCVKEKVYTRDLFFRD"
     CDS             complement(11385..13148)
                     /locus_tag="ctg10_10"
                     /transl_table=11
                     /translation="MYSTIKSIQLLTALLKKYNINKLVLSPGGSDIPIIHSLENDDFFE
                     CHSVVDERSAVYYGIGLAQQTKSPVACICTSGTAVSNYLPGMTEAFYQDVPIVAITADK
                     DPYRLNQLMLQKTQQVNIFESVTKKSVNLPVVRGGNDRWYCERLINEALSELDHHGTGP
                     VHINIPIVENSAVYDCENLPQVRKINRISPDMPSEKWREYAERLSKYKKILVIAGQNNC
                     FSEDDRACVEKFFEKYNCLISVEHMSNLKCKGCLMTYPLSECSMQGMFGELCPDLIISF
                     GNNIASYKLKPMIKAHKEKFVHWQIDTAGRIRDFSDKLTDVFECTPQYFFNCFAENAPQ
                     DSKNDMTYYNMWNDDIKMLDYSSNLPFSNMYVAKKLAEIIPDRSVLHLAILSSTRTMQF
                     FDLKPNVKVYSNIGALGIDGCMSSFFGQASATDELAFCVVGDLSFFYDMNSAGIRGIKN
                     NARIILLNNGGGSEFHFFMGKEKIPTINQYICAEHHKGAKGWIESLGYDYYSATTKEEV
                     DNIIPTLAEESDRPIFVEIFTDMEEDAKLINRLFHDNRMKFGGMKLKMMEKAKSILSPS
                     QIQKAKKLLKK"
     CDS             complement(13324..14403)
                     /locus_tag="ctg10_11"
                     /transl_table=11
                     /translation="MKKVGIVTFHRALNYGAVLQSYALQKTVSSLGAECEIVDYICPKI
                     TADYKPFRIYKNDLLKSFAKSCVMVRRRAKRRDAFKSFFNNYLVKSKKSYTPQNIGELK
                     NDYDLFISGSDQVWSPRCVGFDPAYFLTFADDKQKYSYAASFAVPTLSDEFIDEYKKRL
                     NGFQKFSVREPSGEKLVKELTGRTAETHLDPTLLISADEWKKIAVSKIDKPYILIFTAN
                     PAVSLVDFALKLSKEKNLPVYCINDAPHPVSHGINYIVAPTVEEFVGCFKNAEYVVTNS
                     FHGTAFSVIFNKNLFVEFKNKSGRNIRSEGLLKSLGIDREIVDGNCRETEINWYDVNEK
                     IKNQTIISLDYLKSFVSGD"
     CDS             complement(14403..15317)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_12"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.6e-30,
                     bitscore: 98.0, seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEYTFSVFTPSYNRAKTLPRLYEALKRQTYRNFEWIIVDDGSAD
                     NTKETVEKFISDRPDFNITYKYQTNKGKHIATNVAAQIAKGEFFITIDSDDSVKDDALE
                     TFINEWNKIPDEDRSKYKGISCRTCNESGKTNGCPLPSERFDCSDLDLRLKYKIDGEMW
                     GMTKLEIIKANPYPCVSGLHFYPENIYWDNIGRKYITRFIDTPLRYYINDQENSLTGNA
                     YSAHRETIFVRLHFINECWDYAKSNPKFFIKQFVGLSRDGLLNGKRFSEIKKMPDTFSK
                     RALAVIFYPMGYFLYKKQSGGSR"
ORIGIN
        1 tgtatactat gtctttgcac tgttgtatac tatgttacta cactgcacac attggacgcc
       61 cgccttgatg aaatattttg tttaatcaca tatgttttga tgtgattata attgtgtatt
      121 gaaccttgca cgcattgcgt gcaatcgtat gcgttgcata cgaacgggcg cgaacacggt
      181 tcgccactac aacatacatt gcaaaaataa ttggaatttt atacttggtc aaaatatgta
      241 tgttgctgtg tggttgattt ggctttgcaa ccaaatcaaa tggcggtcac tgaccgccgc
      301 tactgtatgt acaaacaatt actatgttat gctcgggcaa catttgtaat ttactattaa
      361 aaccgtctgc acgaacacac gaacataaaa aatgcggtgg cacattgcca accgcatttt
      421 tattttacat tttcaatttt ccactttcaa tttaaaagct ccgctcggag aacagtggcg
      481 caccatgttt attgcaccgt taccgtaatc gttacgcttg atgttctttt aagcacatcg
      541 gtgactgaat atgttacctt gtacttgcct tttcgggtgg ttactacatt gccgaaaact
      601 tcgatattcg atgttatgtc gttgccgcag gtgtcaacgg ctgttactcc tgcaagggcg
      661 taaaattcgc cgccgctttt gattgtgtaa tcgtttgcac cgctgattat tggtgttgct
      721 ttggcatacg ggcatttttt attgctgtct gtcggatccc atttgttggt aaaatcggtg
      781 attttgattg catccggttt tccgagaggg cctgcatttt ctgcgtcgtc atatatgctt
      841 acatttgtgc ctgtggggca gttgtcataa acccactttg catccgaaac cgcaagtctt
      901 acgcatcctt gtgacgcctg ttcgccaagc ttgttgaact cctcaagctc caaatcttct
      961 tcgctcattg agtagtaggg aacggagtgg aaaagataat cgccagaaat tccgctgatg
     1021 tatcttccga aaacatcgcc cacaagggaa agccattcgg acttgattcc gattgtgtag
     1081 tcacccgtga ttgtcgaatt gtcaagacct gtggagcaaa tcatagccct tatggggatt
     1141 gtgtacttgc ccttttcgtc atatgtgtaa accgtcacgc agtttgccgt gcggttgacc
     1201 ttgattgcgt acagattttt tgccgtgtta cgcttattgt tttcaagctt gtcaagattt
     1261 gccgttgtac aggttgagta gctttgctgt tttttcgtgg ttgattttgc caccgtaacc
     1321 tgaaattccg actttgattt gtcttttgaa attgcagaaa tcagagctgt accctctttg
     1381 agagcgtcaa cccttccgcc gtcatcaacg gtaacaattt tactgtccga gcttgtccat
     1441 ttggtaacag attttgcttt ttctgatgac agttcaataa gctttgattc gccgactttt
     1501 aatgcgagcg aatcgacctt gctcggaaat gtcatatttt cggttactgc cgtatcgggc
     1561 gtctgcggtt ttggagaatt ttgagaatca tttccgaaaa ttcccgttac accgcataat
     1621 atgcaggttg caatgaggac aacacaaagt aaaagaatga aaattttctt tttcatagat
     1681 tacctatcct tatagaattt aacattaaat ggttacaaaa ttttaacctt tgtatattat
     1741 aacttttttt cgacaatctt gcaagtgcta ttttaaatcg gcaagaaatg tggtaaaatg
     1801 tcagtcggag aatgttttgt attttccaaa ctaacaattt atggtgataa ttatggcaca
     1861 tccgattaaa catttcagaa caataacccg tcacaggcac aaggtaattg ccaactgtgc
     1921 aagggcagga attctcagac agggattaat acacgatttg tcaaagtatt cgcctacaga
     1981 atttattccg ggtgcaaagt attttcaggg cacgagaagt cccaatgaaa aggaaagaga
     2041 actgtacggc tattcacagg cgtggatgca tcacaagggc agaaaccgtc accattacga
     2101 atactggaac gattataacc caaagacaaa gcagattgaa aatgttgaaa tgcctgtaaa
     2161 atatgttatc gaaatgttct gcgaccgagt tgccgcaagc aaaatctaca acggcaaaaa
     2221 ttacacggac ggcgctccgt ttacatattt ttgcagaatc agaggcaaac accgtatgca
     2281 ccccaacacc gaggctttgc ttgaaaaatt attggttatg ctgagagatg agggtgaaga
     2341 aaagaccttt gcatatataa gaagtatgaa aaagtgattg tttgtgcgaa tcctcccgtc
     2401 tgaaatatag tcgcaaggct acccctacag aattgcacaa acaaaaacta tctacacgaa
     2461 tagggtacgg cggctcgccg taaggagtga taatatgaaa accgacaggg ttataactgc
     2521 tatgattgaa tattttggaa gtgacaagaa aaggattcac cattttctca aggtttattc
     2581 attcgcaaag acaatcggtg aaagtgaaaa tcttttgccc gacgatcagg agcttcttga
     2641 aatctccgca atcgttcacg acatcggcat aaaggtgagc gaagaaaagt acaattcgtc
     2701 tgcaggaaag tatcaggaac ttgaaggtcc tcacgaggct gaaaagttgc ttgccgctct
     2761 cggttacgaa aaaacattta ttgacaaagt ttgttacctt gtgggacacc atcacaccta
     2821 tggaaatatt gatactttgc cgtaccgaat tttggtagag tcagacttcc ttgtgaacct
     2881 ttatgaggac gattcaagcc gcagtgcagc agagcaggca tatgacaaaa tattccgcac
     2941 aaatacagga aaaaatctgc tgaaaataat gttcctcata ccctaaaatt gtactcattt
     3001 accatagtgt tttgagcgtg aaaaagtggt gtaaaaagta tcccaaaatg cttgacaacg
     3061 cccttaaaaa gtgttatttt aatggtgttg gttatatgat tataaaagtg aataaatgac
     3121 agaatacaag gatgtatgac gattttttca aggagctgac cttaccgggc gtctgcttgg
     3181 aattgagtcg gcattttttt gtgtcatata caaaattcag tattaattat cattatcgga
     3241 ggttttacag taatgagaga agaatggaca aattttgcag gtggcaaatg ggagtccgac
     3301 attgatgtca gagacttcat tcagaaaaac tacacacctt atgacggcga ccagtctttc
     3361 cttgaaggtc ctacagaagc tacagacaag ctctggggcg agctcaagga actccagaag
     3421 gaagaaagag ccaagggcgg cgttcttgat atggaaactg aggttgtaag cggcatcaca
     3481 gcttacggcg ctgcatatct tgataaagac cttgaaaagg ttgtaggtct tcagacagac
     3541 aagcctctca agcgtgcatt tatgccttac ggcggtatca aaatggctga gcagtcatgc
     3601 cagatgtatg gctacactcc aagccctaaa ctccacgaaa tctttacaaa atatcacaag
     3661 actcacaacc agggtgtatt cgatatctat actcccgaga tgaagcttgc ccgtcacaac
     3721 aagattctta caggtcttcc cgacacatac ggcagaggca gaatcgtcgg tgactacaga
     3781 agagttgctc tttacggtat tgaccgtctt atcgaaggca agaaagagga ctttgcagaa
     3841 acaaaccgtc agggtatgag aagaggcgac ttccagcttc gtgaagaaat cgctgatcag
     3901 attcgtgctc ttaacgatat gaaggaaatg gcactttctt acggctttga tatttcacag
     3961 cctgctaaga acgctgcaga ggcagttcag tggctctact tcggttatct tgctgctatc
     4021 aagactcaga acggcgctgc aatgagcgtt ggtcgtgtat caacattcct cgacatctac
     4081 atcgagcgtg accttgagaa cggtacactt acagaatcac aggctcagga actcgttgac
     4141 cactttgtta tgaagtgccg tatggttaag tttgcaagaa ttgagtctta caaccagctc
     4201 ttctcgggcg accctgtatg ggctacactc gaagttgcag gtcttggcat tgacggccgt
     4261 tcaatggtta caaagaacga ctaccgtttc ctccacacac ttgagaatat gggaccttca
     4321 cctgagccaa acctcacagt tctttattct tcaagacttc cggagaactt caagaagtat
     4381 gctgctcata tttcagttac aacaagctca attcagtacg agaacgatga tgtaatgcgt
     4441 cctgtatggg gcgatgatta ctcaatctgc tgctgcgtat ccgcaacaca gacaggtaag
     4501 gaaatccagt tcttcggcgc aagagctaac cttgctaagt gccttctcta cgctatcaac
     4561 ggcggtattg atgaaaagac aaagatgcag gttggtcctg aatatacacc tatcacatca
     4621 gagtaccttg attatgacga agttatcaag aagtatgaca caatgatgga ttggcttgct
     4681 cacctctatg taggcacact taacatgatt cactacatgc atgataagta ctactatgag
     4741 gcagcagaaa tggctcttat cgatacagat gtaagaagaa catttgcaac aggtattgca
     4801 ggcttctcac atgttgttga ctcactcagc gctattaagt acgctaaggt taaggttatc
     4861 cgtgacgagg acggcgttgc tgttgacttt gaaacagagg gcgacttccc aagatacggt
     4921 aacaatgacg agagagcaga taagattgcc gttgatcttc tcaagacatt catggctaag
     4981 ctcaagtatt gccacacata cagagattca gagcctacaa cttctatcct tacaatcaca
     5041 tcaaatgttg tttacggtaa ggctacaggt tcacttcctg acggcagaaa agccggcgag
     5101 cctctttcac cgggtgctaa cccaagctac ggtgcagagc agaacggtct tcttgcttca
     5161 cttaactctg ttgctaagct tccttacgag tacgctcttg acggtatttc aaatactcag
     5221 acaattaacc cgggtgctct cggacacaac gatgacgagc gtgttgacaa cctcgtaaat
     5281 gttatggacg gctactttga tcagggcgca caccacctca atgtaaatgt attcggtaca
     5341 gaaaaactca ttgacgctat ggagcatcct gagaaggaag agtacgctaa cttcacaatc
     5401 cgtgtatcgg gttatgctgt taagttcatc gaccttacaa gagagcagca gctggatgtt
     5461 attgccagaa cctgccacga cagaatgtaa tgtcggacaa cgctgttaaa ggctttgtac
     5521 actcaataga aacttttggc tctgttgacg gtccgggtgt gagatttgtg atttttctga
     5581 gcggttgcgc aatgcgttgc cagttctgcc acaatcccga cacatggaaa cacgatgaaa
     5641 acaccgtgga atacaccgcc gacgagttgc ttaataaagc gcttgcatac cgcccctatt
     5701 ggaaaaataa gggcggtatc acagtaagcg gaggtgagcc gcttttacag attgactttt
     5761 tgcttgattt gttcaagaag gctaaaaagc agggcgttaa tacctgtatt gacacgagcg
     5821 ccaacccgtt tacaaccaaa gagccgttct attcaaagtg gaaagagcta atggaatata
     5881 cggatttgct gttgcttgat ataaagcata tcgacaacga acagcacaaa atccttacag
     5941 gacagccaaa caccaatatt cttgaaatgg caagacagct ttccgatatg ggcaagcccg
     6001 tatggataag acatgttctt gtgcctgaaa gaaatgataa ggacgagtat cttttcagac
     6061 ttgccgactt tatccgttcg ctcaggaatg ttgaaagagt tgaagttctt ccgtatcaca
     6121 cactcggtgt gtacaagtgg aaggctctcg gttatgacta tcctctcgag ggcattaatc
     6181 ccccgacaaa agagcgtgtt aagaatgcgg aaatgattct taacggcgaa aaaacaagag
     6241 attaatttct tatataacaa cggcagtacc gattttttgg tactgccgtt tttgttttga
     6301 tttttatttg ttattctgct tttgttgttt tttcttcagc aaaattgatg aatcaaaggt
     6361 gtattcaaag atttttaagc tgtccttgtt gagaaatctc agcgtaactt ttgggttatc
     6421 aacatcttag aataatagca gataaagcag aattttgcaa taataaaaca gcttgccacc
     6481 gtatccaata taaaactatt gaaaaattgc gcagaatatg gtacaattca cccaacaaag
     6541 cattgatttt acaaacaatt actacatatt tataatttga aaggagtaaa gtaatgaaat
     6601 cagaaagcat aaaaaaattc ggttgtgttt tgcttagtgc cataatgctt tcgggcattt
     6661 cggtgtgtgc tgtatctgcc gaagaaaaat caacggaaat tcatatagtt cacacaaacg
     6721 atattcacgg ctactacaag tccacatcgg gcggtcaaat cggttttgac gcagtcaaga
     6781 ccattgcgga caaggaaaat gccgatttga tacttgatgc aggcgacacc tttcacggac
     6841 agtcatttgc caccgttgaa gagggaaaaa gcattgccga gcttatggac gctgtaggtt
     6901 atgacgcaat gacgcccggc aatcacgatt ggtcatacag tgccgacagg ctgagagagc
     6961 ttgacagaga aagctctttt accatacttg cctcaaatgt ggcagacaca aacggcaaca
     7021 gatattttga caacaacttt tatataaaga atgttactgc tgatgacggc acaaaggtaa
     7081 gagtcggagt tttcggcgtt attgacgaag atttttacac atcaacatcg gcaaagaatg
     7141 ttgaaaatgt tcgctttgaa aattcagccg aaacagcgac agcgtacgcg aattttctca
     7201 gagatgacga gaattgtgat attatacttg cgctgactca taatgcaaac cccgaaaaat
     7261 tcattgccga aacatcgggc attgatgcgg taatcgcagg tcatcagcac attctcattg
     7321 acaaatactg tactgacagt gacggcaaga gcgtaaagct tgttgaggca aactgctttt
     7381 tcaaaaatgt aggtgtgctt actctgacat attccaatga aaagggcgtt accgatgcag
     7441 tcgaaaaaac atattcgtct gccgatactc aggggatgtc cgatgaaaag attgcgtccg
     7501 atatttctgc aattgaaaag cgtgaacaga gcgtactcag cgaagtaatc ggcgagagca
     7561 gtagggagta cgcttacagc tgggaagaac tgagaacaag cgagcaggag ataggcagaa
     7621 tcgtaacagc cgcttatctt gactttacgg gtgctgatgt tgcaatggag aatgcaggcg
     7681 gaatccgttc gggtattcca gagggtaatg tgacatattc cgatttgatt tcaatttcac
     7741 cctacggcaa tgtgcttgtt gaaaaggagc ttacaggtca gcagattatt gatattcttg
     7801 aattttcagt tgaccttatg aagaaaaaca atgcggttta tgaccttcaa aagcaggcga
     7861 taaaggacgg ggaagacccg tatcagtaca gctggccgga taacagcggt tctgtaatgc
     7921 agttcagcgg tttaagtgcg gtatatgact attcaaagcc gtacggcggc agagtgtcag
     7981 atgtaaaaat cggaggaaag gcaattgaca ctttaaaaac ttacagagtg gtttcaaata
     8041 actatgcgtt tgacagttcc gattacggcg atgttgcgtc gctcacgacc gtgaaagaat
     8101 ataccacctg cgaacaaatt ctgcgtgatt atatcagcaa tggcgatttt gaaaaggctg
     8161 ccgcaaatgc aaatcttgtt gagaaatcgt caccgtcgga agaaccgact gctactcagg
     8221 aacagactgt tcagactgct ccgacgggtg agcctgcaac tgtcggtaca acatccgtaa
     8281 atccgacttc ggcaacaggc ggtgccgcaa catcggacag cactccttca cagcctgata
     8341 aaaacggcag cgttcagaca ggagtgacag caacggctgt tatgatgctt gttgtaattt
     8401 tgggcggagt gctttttgcc cttgcagagc gtaaaaagag aatataacac actgacagcc
     8461 atttgtgcaa agattatcag ttgcctattg aaaaatttgt aaaaatgata taaaatagca
     8521 ataagtagaa aaatacggtt tttccgctga tttatattaa tactgaaaga ggtgccggaa
     8581 tggataaaaa caaaaaatta ttctacacaa tcatcggtgc aatctctgca cttgcggctg
     8641 ccacagcagc atttctcgct ttaaaaaagc acagatgcgc agaacagaag cttattgagg
     8701 aaattgacga tattgtttcc gaaaaagagc ctgaggagac tgcaaaggaa gaaccgcagg
     8761 cagaagttac agccgatgag cttgctgagg aagaataagc aacaagttgt tgcacccaat
     8821 tcgggtagca gtatttgcat gtgcaaaagt taaatacccg agcggtgctt tcaattaaga
     8881 attgaaagtt gaaaacagaa aatgatgtcg gcggtgtgcc accgcagtct attcaagaaa
     8941 acagtttaaa aaagaaaatg catcagttgc ccgaaaaggt ctgatgcatt tttgttttgt
     9001 gcgaagtaac cgtaagcctt aattctctct gaatttaaga taaatggcat agacagcctt
     9061 tttaattttt tgaattggcg taagcttgaa acccttcttt ttcataagac tgagaatttc
     9121 tgcataatag tccttgttct gatgtttgag aacatagtcc atatatttgt ttttgtccct
     9181 gtaaaatttc ggaatatcaa aaacattctt atacagttca agttttccga gtgccataag
     9241 ctcaaattgt gttctgacgc acttttcaca gtgaccgcag ttgttctcac cgtagtaaca
     9301 cacattgagg ttatcatatg taatcggaaa ttttgaaatg aagtcaacct tttcaagcct
     9361 tgttttttca agacctgtaa tgtaaaaatc ggtactttcg gtactcagca tacttgccgt
     9421 aaatgcctca tagtgtgccg agccggtgtc gcattgtttt atcgaaaaac tgcttatcgg
     9481 gtatcccgac gcatagtaat agtttttgaa aaatttctgc atacacaaga ccgccgaaaa
     9541 gctgcaataa tgatgaacct ttacatacgg cagggtaaga tgttcaccga gatttgaatt
     9601 aatgtcaatc aacggcatat caaagatttt tgcggatttt tttgcaattt caagacgatt
     9661 ttcgtacagc tcggcagatt gttcgggtgt gtaattagcc gtactcctgt gggagccgac
     9721 attgaaaaag gtaagatgac tcagcttttc cgttctgttt tcggaaagac tgcaaattgt
     9781 gtcaaatgaa tccacacctc tcgaaaatcc tgttgccgac gcatttttgc agcagtagtt
     9841 ttcctgtgta agctcttttg cagatatcga aattttgttg aataattttg aattttttgt
     9901 aagaacggga atgaaaattt cattaagctg aaaacacagt tgcttcgaca tctttgcttc
     9961 tgccgaaata tttagactgt tgttcattgc atacggcaac agcgcaacaa cgaatgcgtc
    10021 ggcactttcg gtcagatagt cagcatactt tgcatcaaca tcaaaccaga gaatgtagga
    10081 aggctttccg ttttcgctga tttttgaaca gagtctggca cgattagcaa gtttttcaat
    10141 tttcggtttg ccgataatca atgtttccat acttttaccc tcaaattaat ctctgaaaaa
    10201 caaatctctt gtgtaaacct tttcttttac acagtcaaga acggagctgt atctgtttgc
    10261 aacgattaca tccgattttg tgacgaactt ttcaaagtcg ttttcaacgc caaagccctc
    10321 gaataaatcg actttaagtg tcggttcgta gatgattaac tcgataccgt tatttttcaa
    10381 aagctccata acgctctgaa ttgagctttg tctgaagtta tcggaatttg acttcattgt
    10441 aaggcggtaa attccgacag cttttggatt tttattcatt atctgtgatg taataaattc
    10501 ttttcttgtc ttgttagatg ttacaacagc gctgataatg tcattcggaa catccgaaaa
    10561 attggccttg agctgttttg tgtcctttgg cagacagtaa ccgccgtagc caaaggacgg
    10621 attgttgtag tgatttccga ttctcggatc aagacacaca ccgtcaatga tacttttagt
    10681 gttaaggttc ttcatttcgg catatgtgtc aagctcgttg aaaaagctga cacgcattgc
    10741 aaggtatgta tttgcaaaaa gcttgaccgc ctctgcctct gtgtagtcca taaagagagt
    10801 gtctatgttt tccttaattg cacagtctgc aagtgccgtt gcaaaagtct cggcagattt
    10861 tttcagttct tcattttcca tatcaacacc gacaatgatt cttgacgggt agaggttatc
    10921 atagagagcc ttgccctcac gcaaaaattc gggactgaaa agaatttttg tgtatttgta
    10981 tttttcaata acactttttg tgtatccaac cggtatagtg gatttgataa ctataaccgc
    11041 atttgggttg cattcaatta caagctcaat tacagcctca acggacgatg tatcaaaaaa
    11101 gtgtctttcg tcatcgtaat tggtaggagt agagataatt acaaaatcag cgtttttgta
    11161 cgcagatttt gcatcaacgg ttgcaaccaa atttaatttt ttgtcagcaa gatattcttc
    11221 gatttccctg tcggcaatcg gagatttctt ttcattgatt aaccttacct tgctttcaac
    11281 gacatcaaca gcggttacct cgtgtttctg cgaaagaagt acagcgtttg aaagacctac
    11341 atagcctgtc ccggcaattg ctattttcat ttggtttcac ctgattactt ttttaataat
    11401 ttttttgcct tttgaatctg tgacggactg agaattgact ttgctttttc catcatcttg
    11461 agcttcattc cgccaaattt cattctgttg tcatgaaaaa gcctgttaat aagctttgcg
    11521 tcctcttcca tatcggtgaa aatctcaaca aaaatcggtc ggtcggattc ttctgcaagt
    11581 gtaggaataa tgttgtcaac ttcttccttg gttgttgcgc tgtaatagtc atatccgagt
    11641 gattcaatcc agccctttgc gcccttgtga tgttcggcgc agatgtactg attgattgta
    11701 ggaatctttt ccttgcccat aaagaagtga aattctgaac caccgccgtt gttgagaaga
    11761 ataattctcg cattgttctt gattcctctg atgcctgcgg agttcatatc atagaagaaa
    11821 ctgaggtcgc ccacaacgca aaaggcaagc tcgtctgttg ccgatgcctg tccgaagaac
    11881 gaagacatac agccgtcaat acccagagcg ccgatattgc tgtaaacctt gacattcggt
    11941 ttcaaatcga agaactgcat agttcttgta ctgctgagaa ttgcaaggtg cagaacagaa
    12001 cggtcgggaa taatttcagc aagctttttg gcaacataca tatttgagaa cggaagattg
    12061 cttgaataat caagcatttt gatatcgtca ttccacatat tgtagtatgt catatcattt
    12121 tttgaatcct gcggtgcgtt ctctgcaaag cagttaaaga aatactgcgg tgtacattca
    12181 aatacatctg tcagcttgtc ggaaaaatct ctgattcttc ccgcagtatc aatttgccag
    12241 tgaacaaatt tttccttgtg agccttaatc ataggcttga gtttatatga agcaatattg
    12301 ttgccgaacg aaataataag atcggggcat aactcgccga acattccctg cattgagcat
    12361 tctgacaaag gataggtcat aaggcagccc ttgcacttga ggtttgacat atgctcaacc
    12421 gatataaggc aattgtattt ctcaaagaac ttctcaacgc acgctctgtc atcttccgag
    12481 aaacagttgt tctgaccggc aatgacaaga attttcttat attttgaaag cctttctgca
    12541 tattcacgcc acttctcgga gggcatatcg ggagaaattc tgttgatttt cctaacctga
    12601 ggaagatttt cacaatcata tacagccgag ttttcaacaa tcggaatatt gatatgcaca
    12661 ggtcctgttc cgtgatggtc aagctccgaa agagcctcgt taataagtct ttcgcagtac
    12721 catctgtcat ttccgccacg cacaacggga agattaacgg atttttttgt aactgattca
    12781 aaaatattga cctgctgggt tttctgcagc ataagctgat ttaatctgta cgggtctttg
    12841 tcagcggtaa ttgcgacaat cggaacatcc tgataaaatg cctctgtcat acccggaaga
    12901 tagttgctta cagccgtacc cgaggtacag atacaggcaa cgggggattt tgtctgttgt
    12961 gcaagtccga tgccgtaata cacggcactt ctctcgtcaa cgaccgaatg acactcaaaa
    13021 aaatcgtcat tttcaagtga atgaattata ggtatatcac tgcctccggg agaaagcacc
    13081 aatttgttga tattatattt tttcagaagt gcagtgagca actggatgct ttttattgta
    13141 gaatacatac gctttcctcc gctttagttt ttgataattc cggaaccgcc tgtaatcaga
    13201 gcggttttgc cgtcaagaat attgttgttc tccttctgta catacacggg aacaacattt
    13261 tttgctttaa aggttttgat tatgctctgt ctgacttttt ttagtgtatt tttaagactc
    13321 aatttaatca ccgctgacaa aggatttaag ataatccaaa gatattattg tctggttctt
    13381 gattttttcg ttcacatcgt accagtttat ttcggtttct cggcagtttc cgtcaacaat
    13441 ttcacggtcg attccaagac ttttcaaaag accttcggag cggatgtttc ttccgctttt
    13501 gttcttgaat tcaacaaaaa gattcttgtt gaaaataaca gaaaacgctg ttccgtgaaa
    13561 cgagtttgta acaacatatt cggcattttt gaaacagccg acaaattcct caacagtagg
    13621 tgcaacaata taatttatac cgtgacttac agggtgaggt gcatcgttta tgcagtaaac
    13681 gggaaggttc ttttcttttg acagtttaag ggcaaaatcc acaagcgaaa ctgccggatt
    13741 agccgtaaaa atgaggatat acggtttgtc aatttttgaa acggcaatct ttttccattc
    13801 gtctgccgaa atcagcaggg taggatcaag atgagtttcg gcggttctgc ccgtgagttc
    13861 ttttacaagc ttttctccgc tcggttcacg aactgagaac ttctgaaaac cgttcagcct
    13921 ttttttatat tcatcaataa attcatcgga caatgtcgga acggcaaagc ttgccgcata
    13981 tgaatacttc tgtttgtcat cggcaaatgt cagaaaataa gcgggatcaa aaccgacgca
    14041 tctcggactc cacacctgat cgcttcccga aatgaacaag tcataatcgt ttttaagctc
    14101 cccgatattc tgcggagtat acgacttttt actctttaca agatagttat tgaaaaacga
    14161 cttaaaagcg tctctgcgtt ttgctcttct ccttaccatg acacagcttt ttgcaaagga
    14221 tttcagaagg tcgtttttat aaatgcgaaa gggtttgtag tcggctgtga ttttaggaca
    14281 gatatagtca acaatttcac actctgcacc gagcgaggaa acggtttttt gcaacgcata
    14341 gctttgaagc acagcgccgt agtttaatgc acggtgaaat gttacaatgc ctaccttttt
    14401 cattatctgc ttccccctga ttgttttttg tacaaaaaat atcccatggg ataaaatatg
    14461 accgcaagag ccctctttga aaatgtgtcg ggcatctttt ttatttcgga aaatctttta
    14521 ccgttgagta agccgtcacg ggaaagtccc acaaattgtt tgataaagaa cttaggattg
    14581 ctctttgcgt aatcccaaca ttcgtttata aagtggagtc ttacgaaaat agtttccctg
    14641 tgagccgagt aagcgttacc tgtcaaagaa ttttcctgat cgtttatgta atatcgcaac
    14701 ggtgtgtcaa taaaacgggt tatatatttt cttccgatat tgtcccaata gatattttcg
    14761 ggataaaaat gaagtcccga aacacacgga taggggttgg ctttgattat ttcaagtttt
    14821 gtcattcccc acatctcacc gtcaatttta tacttcaatc tcaggtcaag gtcggaacag
    14881 tcaaatcgtt ctgacggcag aggacaaccg tttgttttgc cgctttcgtt acaggtgcgg
    14941 cacgaaattc ccttgtattt tgacctgtct tcatcgggaa ttttgttcca ttcgtttata
    15001 aatgtttcaa gggcatcgtc ttttacgctg tcatcggagt caatcgttat aaagaattca
    15061 ccctttgcaa tctgtgccgc aacatttgtt gcaatgtgtt ttcctttgtt ggtctgatat
    15121 ttataggtta tgttaaagtc gggtctgtcg ctgatgaatt tctcaaccgt ttcttttgtg
    15181 ttgtcggctg aaccgtcatc aacaattatc cattcaaaat ttctgtatgt ctgtcttttc
    15241 agcgcctcat ataatctggg cagagttttt gccctgttat atgacggtgt aaaaacggaa
    15301 aaagtatatt cagtcattgc aacctcaaaa tgataataat ttagcttttc ttaaacttct
    15361 tcttaatttt atccttgata agaacgagtt cttttcttga gaaaatgagc ggaacggaaa
    15421 cggcatatcc tgccagtccg cttgctgcac agagaagaag gaatgacatc cagctgtttg
    15481 cgtgtacaaa gctgttgata aagatgaaca tggtgataac aacagcaaag cagaaccatc
    15541 ctctgaaaat agacctgtaa tatgttgtaa gctttatttt caaaatatgt gcggcgtata
    15601 acggaacaaa tactatcgct ttaagaccga taaaaacaga gctgacgcct gcaatagcat
    15661 aaacaccgag cggtgtaaag tgtatgagca gtaaaacgat aataaccgta agaacaccgc
    15721 acacaagcga gataagaacg gaggccttga gcttgttgca tacggtgaaa aggctagaaa
    15781 gagttcttgt gtgacaggta aataggtatg aaatacatac aagcaccgac aaaatctgaa
    15841 ttatggtaat ttcgtccgga gatttggtcg gctgccacaa tgtatagaac ttgttgccaa
    15901 acgcaataaa tcccgcaaga ggtgcagtca tgagaaaact cataatcttt gacgaaaact
    15961 ttgtttcttc aacaagtaag tccgtgttgt cctttgcata aaggattgta aatctgggag
    16021 tgaatatatt tgcaatggtt gtaataaggt tatcaatgca gtgcggaacg gtgtttgcaa
    16081 tcgacaaaag tcccatgagt cccgctccga gagtcaggtt acagattaac aggtcaagac
    16141 ctctgttcag agctgtgctg agataaccga ttgacgacca aattcctgcg gaaatcagaa
    16201 cttttaccag cttgaaactg aaaaggttga agttcatctt tactt
//
