LOCUS       gnlProkkaGHDGKICM_71   15028 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GHDGKICM_71.
ACCESSION   gnlProkkaGHDGKICM_71
VERSION     gnlProkkaGHDGKICM_71
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 17:02:17
            Original ID  :: gnl|Prokka|GHDGKICM_71
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15028
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15028
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[8941:10713]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      8942..10713
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..15028
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15028
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     CDS             complement(481..2364)
                     /locus_tag="ctg71_1"
                     /transl_table=11
                     /translation="MKINIAKSAGFCFGVKRAVDTVYKESSKKNVYTFGPIIHNDEVVA
                     DLERQGVHVINDSEDFKSLSEGTIIIRSHGVSKAIYDEILNAGLDLVDATCPFVRKIHK
                     IVERESGDGRVIIIIGNNHHPEVEGIMGWCHTHPIVIENREQAEGIELDADTKISIVSQ
                     TTFNYNKFQDLVEIISEKGYDINVFNTICNATEERQTEVRELAKKSDAMIVIGGRHSSN
                     TQKLFEISKKECSNTFYIQTKNDLNMEDFSNIGMLGITAGASTPNNIIKEVHESMAEMS
                     FDQMLEESFKTIRNGEVVQGTIIDVKEDEIILNIGYKADGIISRNEYSNDQNLDLTTVA
                     KVGDEMEAKVLKVNDGEGQVLLTYKRLKAEKGNKRLEEAFNNHEVLKAPVAKVLDGGLS
                     VVVEETRVFIPASLVSDTYEKNLKKYDGQEIEFVITEFNPRKRRIIGDRKQLLVAEKKA
                     KQEALFAKIEAGMTVEGTVKNVTDFGAFIDLGGADGLLHISEMSWGRVENPKKVFTVGE
                     KLNVLIKDIQGEKIALSLKFPETNPWLHADEKYAVGNEVTGKVARMTDFGAFVELEPGV
                     DALLHVSQIAKEHIEKPSDVLKVGQEVTAKVVDFKKDDRKISLSIKALDNE"
     CDS             complement(2382..3047)
                     /locus_tag="ctg71_2"
                     /transl_table=11
                     /translation="MYSIAIDGPAGAGKSTIAKAIAEDIGFIYVDTGAMYRAIALYFLR
                     KGIDGHDRKLVAAECPNIHVTLEYDEEGKQQVILNGENVTGYIRKEEVGKMASVTSAVP
                     EVRAALLDLQRDMAKTSDILMDGRDIGTNVLPDASLKIYLTASADVRAKRRYDELKEKG
                     ADCDIEQIKTDIIARDKQDMEREIAPLCQAEDAILVDSSDMSIPQVIDTIISEFKKIK"
     CDS             complement(3183..4424)
                     /locus_tag="ctg71_3"
                     /transl_table=11
                     /translation="MNKVIIVGGGAAGMMAAISASKEGKKVCILEKNEKLGKKLFITGK
                     GRCNITNACPADEFLTHVVTNPRFLYSTFSQFNNEDMMDYLEEIGLPIKTERGQRVFPQ
                     SDRSSDVIDALKKQCKKGGVQIYYHTEVKELLFDEEKENCVGVLLSDGKKMMGDSVILA
                     CGGFSYASTGSNGSGYTLAKQAGHKIKSIEPSLVPFEMKEMWCKDLMGLTLKNIGVRIK
                     AKKKTVYEGFGEFLFTHFGVSGPLVLTASTCLGKYQKELEAGELKLILDLKASLTPEQL
                     DKRFLREFDTYRNKNISNVMERLLPKKMIPVFLEEAQIPEDKKIRDISKKERRHMIELM
                     KNFEMHITGVRGFNEAIVTRGGVNVKEINPSTMESKKVKHLFFAGEMMDLDAVTGGYNL
                     QIAWTTGYVAGKNA"
     CDS             complement(4424..5293)
                     /locus_tag="ctg71_4"
                     /transl_table=11
                     /translation="MEHLNLLQRIEKKSSEFSKGQRRLAQYITENYDIAAYLTASKLGK
                     EAGVSESTVVRFAYQLDYEGYPELQKAIQVIVKTNSNSIQRMSLSSKRYQEKGVLKSIL
                     YTDAERLRDTIQSGVDEEEFNRSVMLINDARRLYILGARSAAYLAGLMGYYFKMMFDNV
                     IIVDANSTSETLEQIYDISDKDVMMGITFPRYSKRTICALQYAKNHGAKTIALTDNMQS
                     PIVEYADCKLIAKSDVMTIVDSLVCPLSVVNAMVTAIALLRKDDVEKRLMALEELWNEY
                     DVYNRSLL"
     CDS             complement(5491..6048)
                     /locus_tag="ctg71_5"
                     /transl_table=11
                     /translation="MPDLGAERVDKVKKLEDYVINIPDFPKPGIIFRDITSILRDPEGL
                     KLSVHELMHCLEGTEFDVVVGAESRGFLFGMPLAYNKSKGFVPVRKKGKLPRETVSKEY
                     ALEYGTAEIEIHKEDIRPGQRIVFVDDLLATGGTAKAAIDLIEELGGVVVKVLFVMELE
                     GLHGRDVLKGYDVESVITYPGK"
     CDS             complement(6151..6996)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1179:hydrolase (Score: 177.4; E-value: 6.7e-54)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg71_6"
                     /transl_table=11
                     /translation="MEQEKKQPDVRLIGLDLDGTTLTSDKVLTPHTKEVLEKCLAEGIQ
                     VLPATGRVKSGIPEYLTQIEGMRYVILSNGASVLDLKEDKVLYQNCIPWERALELFDVL
                     ETYDTFYDIYALGAGWCEARFYDNVENYGIEKHIEKLVRTSRNRIDDLREWMKENKAPV
                     EKINMFFAKEEDRQRAFRELGKIEDLAVTCSLGNNLEINGATCNKGDAMLNLGKILDIP
                     IESIMACGDGNNDFEMVKMAGVGVAMKNGEESLKEVADFVTKTNDEEGVAYAIEHFCNV
                     "
     CDS             complement(7166..8941)
                     /locus_tag="ctg71_7"
                     /transl_table=11
                     /translation="MEKWFIASKRADFNKIGEIFHISPVTARLMRNRSLTTVREMQRYL
                     YGSLSDLYDSHLLKDADKGAEIIKEKIETGKKIRIISDYDVDGVSSNYILYQGLKRCGA
                     DVDYKIPDRVEDGYGINEHLIEKAAGDGIDTIITCDNGIAAAEQIAYGNSLGLTLIVTD
                     HHDIPFQRQEDGSISYNLPSAAAVINPKQKDCPYPFENICGAVVVYKFIQVLYDLFGID
                     RRESEAFLEIAAMATVCDVMPLCDENRIIVKEGLQRIQHTNITGLQALIEANHLEEKKI
                     SSYHFGFILGPCINASGRLTSAKDALELLLCEDKELCRQKAEALTQLNAERKEMTANGV
                     KAAKEYLESTGHGNDKVLVVYLPNCHESIAGIIAGRMKEHYHKPVFVITRTKEGLKGSG
                     RSIEAYHMYKEMNKIKECFDKFGGHPMAAGFSMQEDRLEEFREKLNANATLTEDDFAEK
                     VHIDVALPISYLSESLINEFELLEPFGNENTKPLFAQKDLYIKGMRVLGTTGRCLKLFL
                     SDANGTSIDAMYFGESDGFLEELISFCGKEEAQRIQKGLSHHIWMDVTYYPQVNEWRGQ
                     KNIQIVIQNYRFKNL"
     CDS             complement(8942..10306)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg71_8"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 1.6e-33,
                     bitscore: 104.9, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 3.5e-16, bitscore: 49.7,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 3e-14, bitscore: 43.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 1.6e-20, bitscore:
                     63.3, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHQYKNNGYNIVMDVCSGAIHVVDDVTYDVIALYEEKSLEEIEN
                     ELSYSKEDIEEAYKEVTSLKEEGLLFTEDIYEDYIKEVKSRKTVVKALCLHIAHDCNLA
                     CRYCFAEEGEYKGHRELMSAKVGKAALDFLVANSGNRHNLEVDFFGGEPTMNFGVVKEV
                     VEYGRSLEEKHNKHFRFTLTTNGVLLNDEIMEFANKEMDNVVLSVDGRKEIHDYMRPTR
                     NGKPSYDLIMPKFIRFAESRHQQKYYVRGTFTNRNLDFSKDVLHLADLGFEQISMEPVV
                     GQPEEPYAIQEKDLPQIFDEYDRLAKEMIKREKAGKGFNFFHFMIDLTGGPCVAKRLSG
                     CGSGTEYLAVTPWGDLYPCHQFVGEEKFLLGNVFDGIKRTDICDEFRSCNVYTKKKCKD
                     CFARFYCSGGCPANSYNFHGTIDDSYDLSCDMERKRVECAIMIKAALADTEGEEE"
     CDS             complement(10567..10713)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR03973"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SCIFF"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg71_9"
                     /sec_met_domain="TIGR03973 (E-value: 5.4e-23, bitscore:
                     70.6, seeds: 29, tool: rule-based-clusters)"
                     /sec_met_domain="SCIFF (E-value: 2.7e-22, bitscore: 68.4,
                     seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRVKTLTGNKTYGTTMCKGGCGECQTSCQSACKTSCTVGNQTCE
                     SNK"
     CDS             complement(10813..11193)
                     /locus_tag="ctg71_10"
                     /transl_table=11
                     /translation="MDGISYKKWMERAAGLFLSALIAVLLTMLFLAVFAFAMLKGNLSA
                     SVEKIGLIVMSVMACFVGGFLCGKKNMKKRYLWGLGVGVLYCLFFGVIRVGMGQAFVTD
                     TTAFFTMMLYCAAGGMLGGMLS"
     CDS             complement(11549..11869)
                     /locus_tag="ctg71_11"
                     /transl_table=11
                     /translation="MLLAQSASASSSITMIIAYVILFGAIIYFMTIRPQKKQQKAADEM
                     HAGMQAGDSVLTTSGFYGVIIDIMDDTVIVEFGNNRNCRIPMQKDAIAAVEKPNLTKTE
                     EE"
     CDS             complement(11903..13045)
                     /locus_tag="ctg71_12"
                     /transl_table=11
                     /translation="MYKLLTKDGMAKRGEFETVHGTIQTPVFMNVGTVGAIKGAVSTDD
                     LRTIGTQVELSNTYHLHVRTGDKLIKQFGGLHKFMGWDKPILTDSGGFQVFSLSGLRKI
                     KEEGVYFQSHIDGHHIFMGPEESMQIQSNLGSTIAMAFDECPSSRADRTYIQNSVDRTT
                     RWLERCKKKMQELNSLPDTVNPHQMLFGINQGGVFADIRIEHAKRISELDLDGYAVGGL
                     AVGETHDEMYYILDEVVPYLPENKPTYLMGVGTPANIIEAVDRGIDFFDCVYPSRNGRH
                     GHVYTHHGKLNLFNKKFELDPRPIEEGCQCPSCRTYSRAYIRHLLKAKEMLGMRLCVLH
                     NLYFYNHLMEEIRGAIDEHRYKEFKKTTLEGFLTPEEEYR"
     CDS             complement(13114..14223)
                     /locus_tag="ctg71_13"
                     /transl_table=11
                     /translation="MAGSSFGTLFCMTTWGETHGKGVGVVVDGCPAGLSLCEEDIQKYL
                     NRRKPGQSKYTTKRKEDDKVEILSGVFEGKTTGTPISMAVFNKDQHSKDYSAIKDIYRP
                     GHADYTFDKKYGFRDYRGGGRSSGRETTARVAAGAVAAKVLKELGIEVFAYTKAIGPVQ
                     IDENRFSKEERDKNALYMPDAQAAAQAEEYLQEKMKELDSCGGIVECVITGMPVGVGEP
                     VFDKLSANLGKAILSIGAVKGFEIGDGFAAAASAGSENNDDFYNDNGTVKKKTNHAGGV
                     LGGMSDGSVITFRAAFKPTPSIAQPQQTVNRDGKDTEIVIHGRHDPIIVPRAVVVVETM
                     AAVTVLDLLLQNMGSRLDSVKNFYENEKK"
     CDS             complement(14310..15026)
                     /locus_tag="ctg71_14"
                     /transl_table=11
                     /translation="MKEEEIWIADPQDVNHIRNVLRMKKGEKVSLCCEAKGKEYICGIE
                     EIESDIVKAAIIDINGESRELPVKITLFQGLPKSDKMELIIQKAVELGAAEIVPMATKR
                     AVVKLDAKKAAKKVQRWNEIAKSAAKQSKRGLIPEVKPVMSFKEAVEYGKSMDMLLIPY
                     EDAKGIAHSREVVETVKDKKSLGIYIGPEGGFPEEEVSFAMKAGAEPVTLGHRILRTET
                     AGMTLLSILMFMLEED"
ORIGIN
        1 gtgttgaatg ttcgctaaaa ggctcgcatc caacacttgc tccgaggtca catctgggag
       61 gattaatagg ggcttttttc tgttttttga taaattaaag tgagaattgc agaaatctaa
      121 ttcctgcttt tttaaatgtg gacttaaaaa tgctttctat ataaattttc acataatata
      181 tattatactt ataagaagtt ttatttatag caaaattata taaaatgcca gtgaaacatt
      241 aactataacg aagaaaattt tccacccact cccatcctct tctggagaat cctcaaatcc
      301 tccacagcgg aatttgcgcc aaagtcagaa aatgaaaaag acttataata gcagatgtga
      361 cctcggagca agtgttggat gcgagccctt aagcgaacat tcaacatgcc gcgactaaag
      421 tcacaggtgc tattataagt cttttttatt ttcgtctacc tagccaaatt ccgctaaata
      481 ttattcgtta tctaaagctt tgatgcttaa gctgatctta cgatcatctt tcttgaaatc
      541 tacaacttta gctgtaactt cctgacctac ttttaataca tcagatggtt tctcgatgtg
      601 ctctttagca atctgagaaa catgaagtaa tgcatctacg cctggctcta attcaacgaa
      661 tgcaccgaag tctgtcatac gagcaacttt accagttact tcgttaccta ctgcgtattt
      721 ttcgtcagcg tgaagccatg ggtttgtttc agggaatttt aaggataatg caatcttttc
      781 tccctggata tctttgataa gaacgtttaa tttttcacct actgtgaaaa ctttcttagg
      841 attctcaaca cgtccccagc tcatttcgga gatgtgaaga agtccgtctg ctccacctaa
      901 atcgatgaat gcaccgaaat ctgttacgtt ctttacagtt ccttctacag tcataccagc
      961 ttcgattttt gcaaacagtg cttcctgttt tgctttcttc tctgctacta aaagctgctt
     1021 acggtcaccg atgattcttc tcttgcgagg gttgaactct gtgataacga actcgatttc
     1081 ctgtccgtca tatttcttta agttcttctc gtaagtatcg gatacaaggc ttgcagggat
     1141 gaatactctt gtttcttcca ctacaacact taaaccaccg tcaagaactt tagctacagg
     1201 agcttttaat acttcgtggt tgttaaatgc ttcctctaat ctcttattac ctttttctgc
     1261 tttaagtctc ttatatgtta agagaacctg tccttcgcca tcattcactt taagaacttt
     1321 agcttccatc tcgtcaccaa ctttagcaac tgttgttaag tctaaattct ggtcgttgga
     1381 atattcgttt cttgaaatga taccgtcggc tttatatcca atatttaaga tgatttcatc
     1441 ctcttttaca tcgataatag taccctgaac tacctctcca tttctgattg tcttaaaact
     1501 ttcttccagc atctggtcaa aactcatttc tgccatgctt tcatgaacct ccttgataat
     1561 attatttggg gttgaagccc ctgcagtaat accgagcatc ccgatattag aaaaatcctc
     1621 catattcaaa tcattttttg tttgtatata aaaagtatta ctacattctt ttttacttat
     1681 ctcaaaaagc ttttgagtat tcgaactgtg tctgccaccg attactatca tcgcatcgga
     1741 cttcttcgcc agttccctga cttccgtctg acgctcctca gtcgcattac aaatcgtgtt
     1801 aaaaacattt atatcataac ccttttctga gataatttca actaaatctt gaaacttatt
     1861 gtagttaaat gtcgtctggg acacgataga tatcttcgta tcagcatcta actcaattcc
     1921 ttctgcctgc tctcgattct caattacaat cggatgcgta tggcaccaac ccataatccc
     1981 ttctacttca ggatgatggt tattgcctat aataatgatt actctgccat ccccactctc
     2041 ccgctcgacg attttatgaa tctttctcac aaaagggcag gtcgcatcca ctaaatcaag
     2101 acccgcatta aggatctcat cataaattgc ttttgacacg ccgtgagaac gaataataat
     2161 cgttccctct gaaagagact tgaaatcttc actgtcattg atgacatgaa ccccttgtct
     2221 ttccagatct gcgacaactt catcattgtg aatgatcggc ccgaatgtat aaacattctt
     2281 cttcgaagat tctttataca cggtatctac agctctcttt actccaaaac aaaagccagc
     2341 agattttgct atgttaattt tcatcattta ctccggcaat attattttat ttttttaaat
     2401 tcggagataa tcgtatcaat cacctgcgga attgacatat cagaagaatc taccagtatg
     2461 gcatcttctg cctggcataa tggagcgatc tctctctcca tatcctgctt atctcttgct
     2521 ataatatcgg tcttaatctg ctcgatatca cagtctgcac ctttctcttt caattcgtca
     2581 taacgtctct tcgctcttac atcagcagag gccgtcagat aaatcttaag agatgcatct
     2641 ggcaggacat tcgttccaat gtctcttcca tccatgagga tatccgaagt cttcgccata
     2701 tcgcgctgca gatcaagcag tgcagctctt acttctggaa cagcggatgt cactgatgcc
     2761 atcttaccga cttcttcctt acggatatat ccggtaacat tctcaccatt taagataacc
     2821 tgctgtttcc cttcctcgtc atattctaaa gttacatgaa tgttaggaca ttctgccgca
     2881 acgagcttcc tgtcatgtcc atcaatacct ttacgcaaaa aatataaagc gattgcccgg
     2941 tacattgctc cggtatctac atatataaaa cctatatctt ctgcgattgc ctttgcaatc
     3001 gtgctctttc cagctcctgc tggcccatca attgctatac tatacatgga catttcctcc
     3061 cattcttttg aaacctgact gcgtatacag tgatttcact tttacctaca cttgattagt
     3121 gtaacatatt tttccgaaaa aaaaaactat ttttttataa ttttttaaat tttacgtttt
     3181 ctttacgcat ttttgcctgc tacgtagcct gttgtccatg caatctgcag gttatagccg
     3241 cctgtgacag catctaaatc catcatttct ccggcaaaaa ataaatgttt tactttttta
     3301 gactccattg tagacggatt aatttctttt acatttactc cgcctctcgt gacgattgcc
     3361 tcattaaagc cacggactcc tgtgatatgc atctcgaaat tcttcatcag ctcaatcata
     3421 tgccttcttt cttttttgct gatgtctctt atctttttat cttccggaat ttgtgcttct
     3481 tctaagaaaa caggaatcat tttctttgga agaagacgtt ccatcacatt agaaatattt
     3541 ttattacgat aagtgtcaaa ttctcttaaa aaccgtttat ctaactgttc cggggtaaga
     3601 gaggctttta aatcaagaat cagttttaat tcgcctgcct ctaactcttt ctgatatttg
     3661 ccaagacagg tacttgccgt aagaacaagc ggaccactca ctccaaaatg cgtaaagaga
     3721 aattctccaa atccttcata aactgtcttt ttctttgctt tgatacgcac ccctatattc
     3781 tttaaagtaa gtcccatcaa atctttgcac cacatttctt tcatctcaaa tggaactaaa
     3841 gatggttcta tagacttaat cttatgtcct gcttgctttg caagtgtgta tcccgatcca
     3901 ttggaaccgg tagaagcgta ggaaaagccg ccgcaggcaa ggataacaga atctcccatc
     3961 attttctttc cgtcagacaa aagtacaccg acacagtttt ctttttcttc atcaaaaagt
     4021 agttctttta cttctgtgtg atagtaaatc tgtaccccgc cttttttaca ctgtttcttt
     4081 aatgcatcaa ttacatccga agaccggtcg gactgtggaa atactctctg tcctctctct
     4141 gtctttatcg gaagaccgat ttcttctaaa tagtccatca tatcctcatt attaaactgc
     4201 gaaaatgtac tgtataaaaa tcttggattt gttaccacat gggtaagaaa ttcgtctgcc
     4261 gggcaggcat ttgtaatatt gcatctgcct ttccccgtaa taaaaagctt cttgccaagt
     4321 ttttcgttct tttcaagaat gcagaccttt ttcccctctt tagacgcaga aatggcagcc
     4381 atcataccgg ctgcccctcc gcctacaata attactttgt tcattatagt aaactcctgt
     4441 tataaacatc atactcgttc cagagttctt caagtgccat aagacgcttc tctacatcat
     4501 ccttacgaag taatgcaatc gctgtaacca tcgcattcac cacacttaac ggacatacta
     4561 aagaatccac gattgtcatt acatcactct ttgcaattaa tttacaatct gcatactcta
     4621 caattggaga ctgcatattg tcggtaagtg cgattgtctt cgctccatga ttcttcgcat
     4681 actgaagcgc acagatggtt ctctttgaat atcttggaaa agtaattccc atcataacat
     4741 ccttatcact gatatcgtaa atctgctcta atgtctcgga cgtgctgttg gcatctacga
     4801 taattacatt gtcaaacatc atcttaaaat aatatcccat cagaccggca agataagctg
     4861 cacttctcgc acctaaaata tataatcttc ttgcatcatt gataagcata acggatctgt
     4921 taaattcttc ctcatctaca ccgctctgaa tcgtatcgcg aagccgctct gcatctgtat
     4981 acaaaatact ctttaataca cctttttcct gatatctttt tgaggaaagg gacattctct
     5041 gaatggagtt tgaatttgtc tttacaataa cctgaattgc cttctgtagc tctggatatc
     5101 cctcgtaatc aagctgataa gcaaaacgaa ccactgtaga ctcactgact cctgcttcct
     5161 ttccaagctt tgaagcggta agatatgccg caatatcata gttctctgta atatactgag
     5221 ccagtcttct ctgtccttta ctgaactcgg aagacttctt ctctattctc tgtaataaat
     5281 ttaaatgttc cactctattc ttccacctat tctgtaaaat taagtatatt tcataatact
     5341 ccattttctt ctttttgtaa agcaaaatgc aggatttaaa ggaagaaatt gcaaatagaa
     5401 attcaacttt ataactacag aacaattttt acacaaagag aaactgtgct tccaaaaaat
     5461 tccatccaca cagtttcttt tccttcaaaa ttactttcca ggataagtaa taacagactc
     5521 tacatcatag ccttttaata catcacggcc atgcaatccc tcaagttcca taacaaacag
     5581 aacctttacg acaacgccac caagttcttc gatcagatca atcgcagcct ttgctgttcc
     5641 accagttgct aaaaggtcat ccacaaatac gattctttgt cctggacgaa tgtcctcttt
     5701 atggatttca atctctgctg ttccatactc taaagcatat tctttgctta cagtctctct
     5761 tggcagcttt cctttcttac ggacaggaac aaatcccttg cttttattgt aagcaagagg
     5821 cataccaaat aaaaatccac gggattccgc tccaacaact acgtcaaact ctgttccctc
     5881 taagcaatgc atcaattcat gtacgctaag tttcagtccc tccggatcac gtaaaataga
     5941 ggtaatatct ctgaaaataa ttcccggctt tgggaaatct ggaatattaa tgacataatc
     6001 ttcaagtttt ttcactttgt ccaccctttc tgcccccaaa tcaggcataa aactattaag
     6061 cacagacttt tatcttcgcg ctttttcttc ttatgattaa ttataacaga ttttttatgt
     6121 aaaaaacaac agaaaaacgt ttatttctac ttacacatta caaaaatgct cgatagcgta
     6181 tgctacgcct tcctcatcat ttgtctttgt cacaaaatct gcaacctctt tcaaagactc
     6241 ttctccgttt ttcatagcaa caccgacacc agccatctta accatctcaa aatcgttatt
     6301 gccatcgccg cacgccataa tactttctat cggaatatca agaatttttc caagattgag
     6361 catcgcatct cctttattac aagttgcccc attaatctca agattattac caagagaaca
     6421 ggtaaccgcc aaatcttcta tctttccaag ttcacggaaa gctctctgtc tgtcttcttc
     6481 ctttgcaaag aacatattta tcttctccac tggagcttta ttttctttca tccactctct
     6541 taaatcatca atacgattgc gtgatgtacg aaccagcttc tcgatatgtt tctcaattcc
     6601 atagttttct acattatcat aaaagcgagc ctcacaccag ccagctccta atgcataaat
     6661 atcataaaat gtatcatatg tttctaacac atcgaataac tccaatgctc tctcccacgg
     6721 aatacaattc tgataaagaa ctttatcctc ttttaaatct aatacacttg caccattgga
     6781 taaaataaca tatctcatcc cttcaatctg tgttaaatac tctggaatac ccgattttac
     6841 tcttcctgtt gccggtaaaa cctgaatccc ttccgcaaga catttctcaa gtacttcctt
     6901 tgtatgtgga gttaacacct tatctgaagt gagcgttgtt ccatctaaat ctaatcctat
     6961 caatctgaca tctggctgtt ttttctcctg ttccatattt tctccttatc tatctcttaa
     7021 ttcatagcga ttttgatgta tctctctttt catcctcata ttattctatt gattctcgcc
     7081 ttatttgtca aattaggata gtttttatta attgggaatc taaatagacg aaaaaatatg
     7141 cgaaagaagc actaaaaaat ttatctcata aatttttaaa acgataattc tggatgacga
     7201 tttggatatt cttctgccct cgccattcat ttacctgtgg ataataagtc acatccatcc
     7261 atatatgatg tgacaggcct ttttgaattc tctgtgcctc ttcttttcca caaaaagaga
     7321 tgagttcttc taaaaatcca tcggattctc caaaatacat ggcatctatg cttgttccat
     7381 tggcatccga caggaagagt tttaaacatc tgcctgttgt tccgagtacc cgcattcctt
     7441 ttatgtaaag gtctttttgt gcaaagagcg gttttgtgtt ttcatttcca aatggttcta
     7501 gtaattcaaa ttcattgatg agactttcgg ataaataaga tatcggcaag gctacatcaa
     7561 tgtgaacttt ttctgcgaaa tcatcctcgg taagggttgc gttggcattt aatttttccc
     7621 ggaattcttc taagcggtct tcctgcatag aaaatcctgc tgccatcggg tgcccaccga
     7681 atttatcgaa acattccttg attttgttca tttccttata catatgatag gcttcgatag
     7741 aacggccaga gccttttaat ccttcttttg ttcttgtgat gacaaatact ggcttatggt
     7801 aatgttcttt cattcttccg gcaataattc cggcgatact ttcgtgacag tttggaagat
     7861 atacaacaag taccttatcg tttccatgtc cggtgctttc gagatattct tttgcagctt
     7921 ttaccccgtt agctgtcatt tcttttcgct ctgcatttag ctgtgtgagt gcttctgctt
     7981 tctgcctgca aagttcttta tcttcgcata gaagaagttc taacgcatct tttgcagagg
     8041 tcaaacgacc ggaagcatta atacacggac cgagaataaa tccaaagtga taagaagata
     8101 tctttttttc ttcaagatga tttgcctcaa ttaaagcttg cagcccggta atattcgtat
     8161 gctgtatccg ttgcaggcct tcctttacga taatacggtt ctcatcacac aatggcataa
     8221 cgtcacatac tgttgccatc gccgcaatct caagaaatgc ttcactttct ctacggtcaa
     8281 ttccaaacaa atcgtaaagc acctgaataa acttgtagac aacaaccgct ccgcatatat
     8341 tttcaaatgg atacggacaa tctttttgct tcggattaat aacggcagcg gctgacggca
     8401 aattataaga aatgcttcca tcttcttgcc tttgaaacgg aatatcatga tgatctgtca
     8461 caatcagggt gagtcctaaa gaatttccat aagcaatctg ttctgctgcc gcaattccat
     8521 tgtcacaggt gataatcgta tcaattccgt cccctgctgc cttttctatc agatgttcat
     8581 taattccata accgtcttcc acacggtcag gaatcttata atcaacatcc gcaccacagc
     8641 gttttaatcc ctgatataaa atatagtttg atgaaacacc atctacatca taatccgaaa
     8701 taatccgaat ctttttgcct gtttctatct tctcttttat gatttccgct cccttatcgg
     8761 catctttcaa aagatgagaa tcatataaat cagacagaga gccataaaga taacgctgca
     8821 tttccctaac tgttgttaag ctcctatttc tcatcagacg cgccgttacc gggctgatat
     8881 gaaatatctc accaatttta ttaaaatctg ctctttttga agcgataaac cacttttcca
     8941 tctattcttc ttcgccttct gtatctgcta atgcagcctt aatcataatt gcgcattcta
     9001 ctctcttacg ctccatatcg caacttaaat cataagaatc atcaattgtt ccatggaaat
     9061 tataagagtt tgcaggacag ccgccgctac agtagaatct cgcaaaacag tctttacatt
     9121 ttttctttgt gtatacgttg caggaacgga attcgtcaca aatatcggta cgcttgattc
     9181 catcaaaaac gttaccaaga aggaatttct cttctcctac aaactggtgg caaggatata
     9241 aatctcccca cggtgttact gctaaatact ctgttccgct tccacagccg gaaagtcttt
     9301 ttgctacaca tggaccacct gtaaggtcaa tcataaagtg gaagaaatta aagccttttc
     9361 ctgctttttc tctcttaatc atttcttttg caagtctgtc atactcatca aaaatctgtg
     9421 gaaggtcttt ttcctgaatt gcgtatggct cttctggctg tccaacaact ggttccatgg
     9481 aaatctgttc aaatcctaag tctgcaagat gaagaacatc tttggagaaa tcaagatttc
     9541 tattggtaaa tgttcctctt acatagtatt tctgctgatg tctggactct gcaaaacgaa
     9601 taaacttcgg catgataagg tcatagcttg gcttaccatt tcttgtagga cgcatgtaat
     9661 catggatttc tttacgtcca tcgacactta aaacaacgtt gtccatttct ttattggcaa
     9721 attccataat ctcgtcattt aacagcacac cattggttgt caaagtgaaa cggaaatgtt
     9781 tgttatgttt ttcttcaaga gaacgtccat attctacaac ttcctttaca acaccgaagt
     9841 tcattgttgg ctcaccgcca aagaagtcaa cttcaagatt atgacggttt ccagaattgg
     9901 ctacaaggaa atcaagggca gcctttccaa cctttgcact cataagttca cggtgtcctt
     9961 tatactctcc ttcttctgca aaacagtagc ggcaggcaag attacaatca tgtgcaatat
    10021 gcaggcaaag tgcctttact actgtctttc tgctctttac ctctttaata taatcttcgt
    10081 aaatatcttc tgtaaataaa agtccctctt cttttaaaga agttacctct ttatatgctt
    10141 cctcaatatc ttccttgctg taagaaagtt cattttctat ttcttccaag cttttttctt
    10201 catataaagc aatgacatca taagtcacat catcaacaac atgaatggca ccactgcaca
    10261 catccatgac aatattatat ccattatttt tatactggtg aatcacgtta aatatccctt
    10321 tctatttctt ttatagtttt tatacttaat tttctaaaat atatttttaa tttgaagata
    10381 tgtcctgcta actttaaaat agatatataa tacagaacat tcctgtatac aatattttca
    10441 acttacaata aagtaatctc tgcaaacata cttttccata caagagataa ggtgaactga
    10501 caaaaaagac agttcaccct acttcaagca tatatcagga agcattcttc ctgttgtgct
    10561 ctctaattat ttattactct cgcaagtctg gttacctact gtacaagatg tcttgcaggc
    10621 agactggcag gatgtctggc actcgccaca tccaccttta cacattgtag taccgtaagt
    10681 tttgtttccg gtcagtgtct ttacacgttt cattaataac gcctcctcac ttcatgatct
    10741 agtatgtaaa gcatctaaga tgacactttg taggttatta taacacaaac cctcccgtaa
    10801 gaaaagaact ttttagctta acattcctcc aagcattcct cctgccgcac aataaagcat
    10861 cattgtaaaa aatgctgtcg tatctgtcac aaatgcctgc cccatcccga cgcgtattac
    10921 tccaaaaaac aagcaatata aaacacctac gccaagcccc cataaatacc gttttttcat
    10981 attctttttc ccacacaaaa atcccccgac aaaacaagcc atcacactca taacaattaa
    11041 accaattttt tctacggaag cggaaagatt acctttcaac atggcaaatg caaacactgc
    11101 taaaaatagc attgtgagta atactgcaat taatgcagaa agaaacaggc ctgctgcacg
    11161 ctccatccat tttttatacg aaattccatc cataggctgc accaaaggct tttttatagc
    11221 ctatgaaaag ggttctctgt ttagaacaag cgagacgaaa ttaagagacc gccaatatat
    11281 aaaaaatgct tcgtatcact gcgctcttaa tgctcgtccg cattaagagc ttgctctaag
    11341 gcgcattttt tatatattgg cggtctctta atttctgtct ttgttaaact ggagagtact
    11401 ttcaatttag caaaaaacag atatcctata tttgtggcct tagcgaggat tgaatgtgaa
    11461 cccggaggcg aacattcaac ccgcagtgat agagtcacaa atataggata tctgcttttt
    11521 catttttcgt ctgtcccgct aaccgaaact actcttcttc tgtctttgta agatttggct
    11581 tctccactgc tgcaatagca tctttctgca ttgggattct gcagttacgg ttgttaccaa
    11641 attctacgat tacagtgtca tccatgatgt cgatgattac gccatagaat ccgcttgtag
    11701 tcaatacgct gtctccagcc tgcattcctg catgcatctc gtctgctgct ttctgctgct
    11761 tcttctgtgg acggattgtc ataaagtaga taatcgctcc aaaaagaatg acatatgcaa
    11821 tgatcattgt aatagatgag cttgcgctcg cactctgtgc taataacatg tccttacctc
    11881 cgttattctt ctatataata tattaccggt attcttcttc cggtgtcaaa aaaccttcta
    11941 atgtggtttt tttgaactct ttgtagcggt gttcatcaat tgctccacgt atttcttcca
    12001 ttaaatgatt atagaaatac aggttatgaa gaacacaaag acgcattcca agcatctctt
    12061 ttgccttgag caggtgtctg atataggctc tgctgtatgt ccgacatgac ggacactggc
    12121 atccttcctc gattgggcgg gggtctaatt caaacttctt attaaaaaga tttaactttc
    12181 catgatgcgt atacacatgt ccgtgtcttc catttctgga aggatataca cagtcaaaga
    12241 agtcgattcc tctgtcaact gcctcaataa tatttgctgg ggttcctaca cccataaggt
    12301 aagttggttt attttccggc agatacggaa caacttcatc aaggatatag tacatctcat
    12361 catgtgtctc tcctactgca agtccgccaa ctgcataacc atctaaatca agctcactga
    12421 ttcttttagc gtgctcgata cggatatccg caaaaacacc accctgatta ataccaaata
    12481 acatctggtg tggatttacg gtatctggca ggctgtttaa ttcctgcatc ttttttttac
    12541 agcgttctaa ccatcttgtt gttctgtcaa cagaattctg aatgtaggtt ctgtctgccc
    12601 gacttgaagg acattcatca aatgccatcg caatcgtaga accaagatta gactgaatct
    12661 gcatactttc ttccggtccc ataaaaatat gatgtccatc aatatgtgac tggaaatata
    12721 cgccttcttc ctttatcttt cgaagacctg acagagaaaa cacctgaaat ccgccagaat
    12781 cggtaaggat tggtttatcc catcccataa atttatgaag cccgccaaac tgtttgatta
    12841 gtttatcacc tgttcttaca tgaagatgat aggtattaga cagctccacc tgcgttccga
    12901 ttgtacgaag gtcatccgtg cttacagcac ctttgattgc tcctactgtt cctacattca
    12961 taaaaacagg agtctgtatc gtaccatgga ctgtctcaaa ctctcctcgt ttggccatgc
    13021 catctttcgt taataactta tacatatact ctccttaact ttacacataa atttgatttt
    13081 atcataaaca aagcaaatgt acaacctcta tccttatttt ttctcatttt cgtagaagtt
    13141 ttttacgcta tctaagcggc tccccatatt ctgaagcagc agatcaagaa cagttaccgc
    13201 tgccattgtc tctacaacaa cgactgctct tggcacaata atcgggtcat gtcttccgtg
    13261 aattacaatt tctgtatctt tgccatctct atttactgtc tgctgtggct gtgcaatcga
    13321 tggagttggc ttaaatgctg cacgaaatgt aattactgaa ccatcgctca ttccaccaag
    13381 cacaccacct gcatgattcg ttttcttttt caccgtacca ttatcattat aaaaatcatc
    13441 attattctca gaaccagcac ttgctgccgc cgcaaatcca tctccgattt cgaagccttt
    13501 tactgctccg atagataaaa ttgcttttcc aagattcgca cttaatttat caaataccgg
    13561 ctcaccaaca ccgacgggca ttcctgtaat tacacattcc acaatgccac cacaggaatc
    13621 taactctttc attttctcct gaagatactc ttccgcctgt gctgctgcct gtgcatccgg
    13681 catatataat gcgttcttat ctcgttcttc ttttgaaaat ctattttcat caatttgaac
    13741 tggcccaatt gcttttgtat aagcaaatac ttcaatgcca agttctttta atacttttgc
    13801 tgctactgca cctgctgcta ctcttgctgt tgtctctctt cctgaagaac ggccgccacc
    13861 gcgataatca cggaaaccat acttcttatc aaatgtataa tctgcatggc ccggacggta
    13921 aatatccttg attgcagagt aatcttttga atgctggtct ttattaaata ccgccataga
    13981 aattggagtt cctgttgtct ttccctcaaa aactcccgat aaaatctcca ccttatcatc
    14041 ttcttttcgc tttgttgtgt actttgactg tcccggcttt cttctattca aatacttctg
    14101 tatatcctcc tcacaaagag aaaggcctgc cggacaaccg tccactacaa cacccacacc
    14161 ttttccgtgt gtttctcccc atgttgtcat acaaaacaat gtcccaaatg atgaacctgc
    14221 cattttgtcc tcctgttaaa attctatcgt caaacagagt atcctctgtt tgacttttta
    14281 tcaattaaat ttctactatc tacaccaaat caatcttctt ctaacataaa cattaatata
    14341 gaaagtaatg tcattcccgc cgtttccgtc cgcaaaatgc ggtgcccaag tgtaaccggt
    14401 tctgctcctg ctttcatcgc aaaagaaacc tcttcttccg gaaaaccacc ttccggtccg
    14461 atataaattc ccagactctt tttatccttt actgtttcta ccacttctct ggaatgtgcg
    14521 attcccttgg catcctcata cggaatgagt agcatatcca tactctttcc atattccaca
    14581 gcttctttaa aagacattac gggctttact tctggaatca gacctctctt tgactgctta
    14641 gccgcacttt ttgcaatctc attccatcgc tgtactttct ttgctgcctt cttcgcatca
    14701 agctttacaa ccgctctttt tgttgccatc ggcacaatct ctgccgcccc gagttctacc
    14761 gctttttgaa tgataagttc catcttgtca ctctttggaa gtccctgaaa aagcgtaatc
    14821 tttaccggca gttctctcga ctctccgtta atatcaataa ttgccgcctt gacgatatct
    14881 gattctatct cttctatacc acaaatgtac tcctttccct ttgcttcgca acaaagagaa
    14941 actttttctc cctttttcat acggagaaca ttacgaatgt gatttacatc ctgcgggtct
    15001 gcaatccaaa tctcctcttc tttaatac
//
