LOCUS       gnlProkkaDKNCEJAB_36   15654 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DKNCEJAB_36.
ACCESSION   gnlProkkaDKNCEJAB_36
VERSION     gnlProkkaDKNCEJAB_36
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 17:34:14
            Original ID  :: gnl|Prokka|DKNCEJAB_36
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15654
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..2289)
                     /locus_tag="ctg36_1"
                     /transl_table=11
                     /translation="MSMKVLTVLQFISIFTIYTGLFIAVPALLLHRRLKDEIFSVRFFF
                     YIVLGHFYLINLVLFLQLLHISGRFTLILGSALPVVISLVHTKRVSPKKIGHIIGNRTS
                     HVIRETLGIKLLLLEIVQWIGRKIKKLCGRMCGLIIRHFADGVLFVVFTATVLVMYGTN
                     MINTYGYCASDIPVHNYWINAMGQNDVFVAGIYPFGFHCVIYYIHTVTGIETYVLLRLF
                     YVVQVLYIHYALLAFLKACCRTSYCAWGAVFVYVLAAFFNRNTYSRYYSSLPQEFGMIF
                     ILPGIYFMYAFLKQRKIEVNQCKKERNAAGLKTWKCKSTRYLMGFIAGFGLTLIVHFYD
                     TMVAGLFCIGIAGGYLLRIFKKEYFFRVLATGLLSIFLAVLPMGIAFLQGTPLQGSLGW
                     GLNVINGSNNTGAEEEDEADIPGSEKEEINTNTQSVTDQSMTDSTDTAGSMTDQTMSEN
                     GVENAQMTEGTKVKTTRFGMLVEKIRFRITDITQNGLDYLWTGVHNVVMLQASVPWMLF
                     IFGCEGFCLIGGLLFTLIGKHDYGSMLMSAGFGLLLLMMFLSAWRFGLPHIMDASRCSI
                     YVAYMIPVAIGLGMDGMVTLVFGFFKRNIWMNLVSLMTSAALAATLVNGNQIRTPSILT
                     ALQSNAAITCLANIKRENEKYKYTICSANDELRMMEDYARHEETITFLRSMEGDAVNGN
                     LTLPTDRVYFFIEKIPLDYTVAYEGSGQLISEEGAKKPLPTAGDISVYEGENRWIVMSR
                     MYYWAQAFME"
     protocluster    1..15654
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[5402:5654]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5403..5654
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..15654
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15654
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(2304..3215)
                     /locus_tag="ctg36_2"
                     /transl_table=11
                     /translation="MTVAEKRFCIVLLINTAVAVLYVIGNSRIRQKEKNTDILMKGIMM
                     FLCPVVGPLFFLAGLVFNKVFFRQNVDLEDVIFSKERVKTHLRADEEREGNLVPIEEAL
                     AISDKDSLRTLVMNVVRGDVQNSLASISLALNSEDTETSHYAATVLRDALNDFRKRAQE
                     LYLQMKQEGVDAAEAACILIEYMHGVLIQEVFHEKEQQTYIDMMEEACNFLDEKYQEKL
                     QASYIEGLCVLLLKIKDFKRMKYWCDKSRELYPAELSTYTCYLKLYFTEGNKKHFFDEL
                     EKLKNSDIVIDRETLELIRIFS"
     CDS             complement(3212..5389)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score: 79.5;
                     E-value: 4.8e-24)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg36_3"
                     /sec_met_domain="RmlD_sub_bind (E-value: 4.5e-20, bitscore:
                     62.6, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNILLVGNAGNFMRLMINRLNKEGHRVFVLTEEPKKGYSLKKVFE
                     VYHFSYEDACVREVLESIMPQVVVFLGAYDHNFSWNRVENTAASYAAGLTNILMNYTAL
                     KKGRFVYLSSESVFGGGSAQFMTEDDPTGAYSKKGQAIAIGEDICKNYARMGNDVVILR
                     LDHLYGEIRKKEDTDTICADMCLEAVQTGEIIASQNEKIMLLHEADAVEFIYQIMVAKD
                     HKHTLYQLSSGEKMSRYELAQAVAAGMENEVSIVEEENKKYREVMLSGKRYDEEFGSRV
                     LHHAGTDVEKIAAYFSRHVSEFTDAGQKKGHLFRRLGSRTKEIITNLIPFMENLICFIP
                     FFMLNNRAVGSEYFQNIDFYLLYVLLFALVYGQQQATFSALLAVAGYCFRQMYHRSGFD
                     VMLDYNTYVWIAQLLILGLAVGYLRDQLRAMREEQRHEVSYLTKQLDDISDINVSNVRV
                     KEILANQIVNQNDSFGKLYEITSSLEQYEPCEVLFYAAEVLAKLMGSKDVAIYTVANRS
                     YARLFSATSEKARSLGNSINYSEMDAMYTVLAGKKVYINKNMDERYPLMANAIYSEDEM
                     QLILMIWGIPWERMTLGQANMLTVIGYLIQNAVVRANRYISALEQQRYIKGTNILEPEA
                     FLALVKAYLNARDKGLTQCALLSVDTKENDRDEVGKRLIKLLRQSDYVGELEGGKMYAL
                     LANTSAKDATMVKERFEKEGVSCQIQEDVFV"
     CDS             complement(5403..5654)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_4"
                     /sec_met_domain="PF05402 (E-value: 3.6e-15, bitscore: 46.9,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 4.4e-11,
                     bitscore: 33.6, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEWYQLRQAAGAYWLLDMEQGEQYKKPFMLNECGAYIYRAYISG
                     MSEDEITQAFAKEYGLSFSCAQSDVGQFMMELRQQGII"
     CDS             complement(5695..6540)
                     /locus_tag="ctg36_5"
                     /transl_table=11
                     /translation="MSEIILRKYHGVGNDYLIFDPKKNDVVLNERLIRQLCRRNIGVGA
                     DGILYGPVMEDKKIKVRIFNPDGSEAEKSGNGIRIFSRYLKDAGYVKERQYYLTTKAGE
                     TLVTFLDDAGSCMRVDMGYAVFEAEQIPALGFEGEVVGESIFFCDNFYNATCVSMGNPN
                     CVIMLERVDREKALHLGPYVENAKYFPNRINMQLCQIVDEKNIQVEIYERGAGYTFASG
                     TGACAAAAASHRLGLVEDAVTVHMHGGDLFIEFEKDGRIFMTGPVVYIGKITVAEQFFA
                     "
     CDS             complement(7211..7441)
                     /locus_tag="ctg36_6"
                     /transl_table=11
                     /translation="MDCLVGSVAQGTADADRVIVAQVTSYLTYNHGNCVSGKLNPDRRI
                     EVVDGLDQADTADLKQIIYIFVIAGKTFDDT"
     CDS             complement(7426..7527)
                     /locus_tag="ctg36_7"
                     /transl_table=11
                     /translation="MSSLEMPDSAAISSRVGSLFSVFESISLVWIAL"
     CDS             7610..7840
                     /locus_tag="ctg36_8"
                     /transl_table=11
                     /translation="MDQISDKKNREENWIEELSLNDALDRLNERENYILKLRFFEGKTQ
                     MEVADEIHISQAQVSRLEKSALKSIRHYLSL"
     CDS             complement(7837..9447)
                     /locus_tag="ctg36_9"
                     /transl_table=11
                     /translation="MVLEFLGAAHEVTGSCHYLSFGDKHILVDCGMEQGPDLYTNQEIP
                     VNAAMIDYVFVTHAHIDHSGLLPLLYNHGFRGKIYCTLATNELCNIMLKDSAHIQMFEA
                     EWRNRKAKRAGKPEVVPLYDMNDAMSVLSHFVPCDYQKKIKVCDGLEIRFVDAGHLLGS
                     SSIEMWVRDDDGTEVKLAFSGDIGPGNRPLIKDPEYIKDADYVIMESTYGDRKHNTPPD
                     FAIALAKVIKETLYERGGNLVVPAFSVGRTQEMLYFIRRIKSEHLLPEFENFEVYIDSP
                     LAVEATSIFNKSVEECFDEDARALVQQGINPIGFPGLKMAITSDESKMINFNDNPKVII
                     SASGMCEAGRIRHHLKHNLWRKDSTILFVGYQVPGTLGFSLLNGAKEVRLFGETIEVAA
                     RIENLPGISGHADVEQLTKWAAAFENKPKKVFVVHGEDKVTEQFADHLKDTLGYEAYAP
                     FPGDAFDLATGEQVREGSRERAEKKITEKSRASSNVFARLLAAGQRLLTVINKCEGMPN
                     KELGKFADQINALCNKWDR"
     CDS             complement(9575..10306)
                     /locus_tag="ctg36_10"
                     /transl_table=11
                     /translation="MYIKFAIPKIRTMIFPGIFRKKKDEVHYIGGAEVLPPPLAGEDEA
                     VCIEMLTSDESGQIARKRLIEHNLRLVVYIAKKFDNTGVGVEDLISIGTIGLIKAINTF
                     NSGKNIKLATYASRCIENEILMYLRRNSKTRMEVSIDEPLNVDWDGNELLLSDILGTDE
                     DVIYHDIETDVEHRLLKTAIGKLSGRERMIIELRFGLNSIDGEEKTQKEVADMLGISQS
                     YISRLEKKIMGRLKKEIVRLE"
     CDS             complement(10320..11108)
                     /locus_tag="ctg36_11"
                     /transl_table=11
                     /translation="MFLLENLFMDYMAILGCNCLLKRRIHPGRLFAVSLMFSLIHLFLV
                     CFINNRILYFLIAHFVLNTGMVFFCFGWEGKRSYLENWVVTYFMCVIQGGALEWLLEQH
                     IFSQNEILQMLVAAAVVVTAVICFGERRVCGNHIYPAELKKGERYIRLRAYWDSGNQLT
                     DPYTGQEISILSGSVAEKFFTKEKDLVRFVPYRSLGEKDGLIAVTNVDEMTVFQGKRAV
                     KIPHAAIGTADKMLFDGKEYEMLLNASSIMPQGGKTENKN"
     CDS             complement(11400..12596)
                     /locus_tag="ctg36_12"
                     /transl_table=11
                     /translation="MLEIKTTEADTSAKIIVIGVGGAGNNAVNRMIDESIGGVEFIGVN
                     TDKQALALCKAPTLIQIGEKLTKGLGAGAQPEIGQKAAEESMEELSAAVKGADMVFVTC
                     GMGGGTGTGAAPVVAKIAKEQGILTVGVVTKPFKFEAKQRMLNALSGIDRLKESVDTLI
                     VIPNDKLLEIVDRRTTMPDALKKADEVLQQAVQGITDLINLPALINLDFADVSTVMKDK
                     GMAHIGIGNAKGDDKAIEAVKLAVASPLLETTINGASHVIINISGDISLMDANDAASYV
                     QDLAGDNANIIFGAKYDESMTDEATITVIATGLENAAAPKSKIMPDLRYGNTTNVTRPV
                     GTPGINRQAANLGASVQAHTQTQTAAPSFSGIQRPRQPESTVQPMDIKIPDFLKNSRK"
     CDS             complement(12713..13468)
                     /locus_tag="ctg36_13"
                     /transl_table=11
                     /translation="MRIKEQRKRKKRRRIGICIFLVVLMLFALAALIVVKVFTVQNVVV
                     EGNSLYSADQIKNMVLDDDYSWNSLYVDLKYRFVDVGEVPFVDTMEISLDDPHTLRISV
                     TEKGILGSFYIDTLGQYAYFDKDGFVVETSSDVIEGVPKITGVTCDSVVLYEKLPLEDT
                     KLLRNLLTLTQLLKKYELEPEEIHYDSAMQPQLTYGTIAVNVGSEDYLTQKIARLSAIM
                     PQLSGLSGILHLETWTPDTTDIVFDRADL"
     CDS             complement(13471..14589)
                     /locus_tag="ctg36_14"
                     /transl_table=11
                     /translation="MARRRKNEKRQKSIRYFDYSLLFLIIFLLCFGLIMLYSTSSYYGS
                     TRFNDAAYYVKRQMYASALGIVAMLFISRIPYKFWMQLSTLAYFVALVLCTAVIFVGTS
                     AKGQSRWLRIGPIQFQPSEIAKIAVIIFLATIIYKTPKRIGEIMSLLKIMLLISPVLAV
                     VAYNNLSTAIIILGIAVCMLFVASPKYLQFILMGIGVCLFGALFILLASYRAERVMIWL
                     HPEDYEKGYQTLQGLYAIGSGGLFGKGLGESMQKLGFIPEAQNDMIFSVICEELGLFGA
                     VCLILLYLLIIWRLMIIANNASDLYGALIVVGIMAHLSIQVLLNIAVVTNTIPNTGVSL
                     PFISYGGTSISILLAEMGLALSVSRGIKLEVA"
ORIGIN
        1 ttccataaat gcctgtgccc agtaatacat tcttgacatt acgatccatc ggttttcacc
       61 ttcataaacc gaaatatctc ctgctgttgg cagcggtttt tttgctcctt cttctgaaat
      121 gagctgtccg cttccctcat atgccacggt ataatcaagt ggtatcttct caataaagaa
      181 atatacgcgg tctgtcggca gcgtcagatt tccattgacc gcatctcctt ccatactccg
      241 taaaaatgta attgtttcct catgacgtgc ataatcttcc atcattcgca gttcatcatt
      301 cgcagaacag attgtatatt tatacttttc gttctcccgc tttatatttg ccagacaggt
      361 aatcgccgca ttcgactgca gtgccgtcaa tattgacggc gtacggatct gatttccatt
      421 gacaagtgtc gcagcaagtg ccgctgacgt catcagtgaa acaagattca tccagatatt
      481 ccgcttaaaa aatccaaaga ccaatgttac cataccgtcc attccaagtc cgatcgctac
      541 cggtatcata taagcgacgt agatactgca ccggcttgca tccatgatat gtggcagtcc
      601 aaaacgccat gcagaaagaa acatcatcaa aagcagcaga ccaaatcctg cggacatcag
      661 cattgatcca taatcatgtt ttccaatgag cgtaaacaat agtccaccga tcaggcagaa
      721 tccctcgcac ccaaaaataa acaacatcca tggcacgctt gcctgaagca ttacaacatt
      781 gtgcactcct gtccacagat aatccaatcc gttttgggta atatccgtaa tccggaaacg
      841 tatcttttcc accagcatac caaaccttgt tgtttttacc ttcgtccctt ctgtcatctg
      901 tgcattttcc acaccatttt ctgacattgt ctgatccgtc atgctcccgg cagtatccgt
      961 actatccgtc atgctctgat ccgttacact ctgtgtattt gtatttattt cttccttttc
     1021 actgccaggg atatctgctt catcttcctc ctcagcaccc gtattattgc tgccattaat
     1081 tacattgagt ccccagccca gcgatccctg taaaggcgta ccctgtaaaa aggcaattcc
     1141 catcggaagc actgccaaga agatacttaa aagaccagtc gcaagaaccc tgaaaaaata
     1201 ctcctttttg aaaatacgca acaggtatcc tcctgcaata ccgatacaga acaaccctgc
     1261 taccatagta tcataaaaat gtacgatcag cgtaagtcca aatcctgcaa taaatcccat
     1321 aagataacgg gtacttttgc atttccaggt ttttaatccg gcagcgtttc tttccttttt
     1381 gcattgattc acttctatct tccgctgttt taaaaaggca tacataaaat aaatgccggg
     1441 caggataaat atcatgccaa attcctgagg cagcgaactg taataacgcg agtaagtatt
     1501 cctgttaaaa aatgcagcaa gtacatagac aaatacagct ccccatgcgc aatacgatgt
     1561 cctgcagcac gctttcaaaa atgccagaag tgcataatgg atatataaga cctgcaccac
     1621 ataaaaaagc cggagcagca catacgtttc aatccctgtt accgtatgga tataataaat
     1681 tacgcagtgg aatccaaatg gataaattcc agctacaaac acatcattct gccccatcgc
     1741 attgatccag taattgtgta ccggtatatc ggatgcacaa taaccgtatg tatttatcat
     1801 attggttcca tacattacca gaaccgttgc agtaaataca acaaacagca ctccatctgc
     1861 aaaatgcctg atgatcagcc cacacattct gccacacagt ttcttaattt ttctgccaat
     1921 ccactgtaca atctccagaa gaagtaattt aatgccaagc gtctcccgga tcacatggga
     1981 tgttctgttt cctatgatat gtccgatttt tttaggtgaa actcttttcg tatgtaccaa
     2041 ggatataacg actggaagtg cactgcccaa aatcagcgta aatctgcctg aaatatgaag
     2101 cagctgaaga aataatacca gattgatcag atagaaatga cctaatacga tataaaagaa
     2161 aaaccgtaca ctaaatattt catcttttaa cctgcggtgc agaagcagtg ccggaactgc
     2221 gataaaaagt cccgtataaa ttgtgaaaat gctgataaac tgtaacacag tcaggacttt
     2281 catcgacact gccatcacct cctttagcta aaaatacgaa ttaattccaa tgtttccctg
     2341 tcgatcacaa tatctgaatt ttttaatttt tccaattcat caaaaaaatg ttttttgttt
     2401 ccctctgtaa aataaagttt taaataacag gtataggtag ataattctgc cggatagagt
     2461 tccctgctct tatcgcacca gtatttcatg cgcttaaaat cctttatctt aagaagcaga
     2521 acgcaaagtc cctcaatata ggaagcctgc agtttctcct ggtatttttc atccagaaaa
     2581 ttacatgcct cctccatcat atcgatgtag gtctgctgtt ccttttcatg aaacacctcc
     2641 tggatcaata ccccatgcat atactcaatc aggatacagg ctgcttctgc cgcatcaact
     2701 ccctcctgtt tcatctgaag gtaaagttcc tgtgcacgct ttctgaaatc attcaatgca
     2761 tcccttaata ctgtagcggc ataatgtgat gtttccgtgt cctcactgtt taacgcaagc
     2821 gagatggatg ccagagaatt ctgtacatcc ccacggacca cattcatgac cagcgttctt
     2881 aaactgtctt tgtcgctgat cgcaagtgcc tcctcaatcg gtactaaatt tccttccctt
     2941 tcctcatctg cccgaagatg tgtctttaca cgctccttgc tgaaaataac atcctcaaga
     3001 tccacgttct gccggaaaaa aaccttgtta aacaccagtc ccgccaaaaa aaacaacggt
     3061 cccactaccg ggcagagaaa catcatgatc cccttcatca gaatatctgt atttttttct
     3121 ttctgcctga tcctgctgtt tcctatcaca tataaaacag caacagccgt attgatcaga
     3181 agaacgatac aaaatctctt ttctgcaacc gtcatacaaa tacatcctcc tgtatctggc
     3241 aggacacacc ctctttttca aatctttctt ttaccatggt tgcatctttt gcactggtat
     3301 ttgcaagaag cgcatacatt tttccacctt caagttcacc gacataatcg ctttgtctaa
     3361 ggagtttgat aagccttttc ccgacctcat cacggtcatt ttcctttgta tccacggaaa
     3421 gcagtgcaca ctgtgtcaat cctttatcac gcgcatttaa atacgccttt acaagtgcta
     3481 aaaaggcttc cggttctaat atattcgttc cttttatgta acgctgctgc tctaaggcag
     3541 aaatataacg gtttgcacgc accaccgcat tctgaatcag ataaccgata accgtcagca
     3601 tattcgcctg tcctaacgtc atccgctccc acggaattcc ccagatcatc agaatcagct
     3661 gcatctcatc ttccgaataa atggcatttg ccataagcgg atatctttca tccatatttt
     3721 tattaatata aactttcttc ccggcaagca ccgtatacat ggcatccatc tcgctgtaat
     3781 tgattgaatt accgaggctg cgtgctttct ccgatgttgc agaaaaaaga cgtgcatagg
     3841 aacggtttgc caccgtatag attgccacat ctttgcttcc catcagtttt gcaagtactt
     3901 ccgccgcata aaaaagtacc tcacagggtt catactgctc taaactggat gtgatctcat
     3961 ataattttcc aaaactgtca ttctggttta cgatctggtt tgcgagaatt tcttttaccc
     4021 tgacattgct gacattgata tccgaaatat catctaactg cttggttaag tatgatactt
     4081 catgccgctg ttcctccctc attgcacgaa gctggtctct cagatatccc actgccagac
     4141 ctaagatcaa aagctgtgcg atccagacat aggtattata gtcaagcata acatcaaatc
     4201 cgcttctgtg gtacatctgc cggaaacagt accctgccac ggcaagcaat gcagaaaatg
     4261 ttgcctgctg ctgcccgtat acaagtgcaa acaacagcac atacagaaga taaaaatcaa
     4321 tattctgaaa gtattcactt ccgactgcac ggttattcaa catgaaaaac ggaataaaac
     4381 aaatcaggtt ttccataaaa ggaatcagat tcgttatgat ttcctttgtc ctgctgccta
     4441 atcttcgaaa cagatgtccc tttttctgcc ctgcatctgt aaattcagat acatgtctgc
     4501 tgaaataagc cgcaatcttt tccacatctg ttcctgcatg atgaagcaca cggcttccaa
     4561 attcttcatc gtatctttta ccggaaagca taacttcccg gtattttttg ttttcctctt
     4621 ctacgatact gacctcattc tccattcctg cggcaacagc ctgggcaagc tcataccgtg
     4681 acattttctc cccggaagat aactgataga gggtatgttt atggtccttt gccaccatta
     4741 tctggtagat aaactccacc gcatccgcct catgcagaag cattattttt tcattctgcg
     4801 acgcaatgat ctctccggtc tggactgctt cgaggcacat atccgcacag atcgtatctg
     4861 tatcctcttt ctttcgtatt tccccataca aatgatcgag gcggagaatc acaacatcat
     4921 tccccatcct tgcataattt ttacagatat cttctccgat agcgatcgcc tggcctttct
     4981 tgctgtatgc cccggtagga tcatcctctg tcataaactg tgcgcttcca ccgccaaaaa
     5041 cactctccga agaaagatag acaaacctgc ctttctttaa agcggtataa ttcatcagta
     5101 tattcgtaag tcccgctgca taggacgccg ctgtgttttc caccctgttc caggaaaaat
     5161 tatggtcata tgcccccaga aaaactacta cctgtggcat aatactctct aatacctccc
     5221 gcacacaggc atcctcatac gaaaaatgat acacttcaaa tactttcttc aggctgtatc
     5281 ccttctttgg ttcttctgtc agcacaaaga ccctgtgtcc ttccttattc agtctgttga
     5341 tcataagccg cataaaattg ccggcattcc caactagcaa tatattcata cctgctccat
     5401 tctcaaataa ttccctgttg tcttaactcc atcataaact gccctacgtc gctttgtgcg
     5461 caggagaatg acaatccata ttcttttgca aatgcctgcg tgatctcatc ctcagacatt
     5521 cctgaaatat acgcacgata tatatatgca ccgcactcgt tcaacatgaa tggcttttta
     5581 tattgttccc cctgctccat atccaaaagc cagtatgccc ccgctgcctg gcgtaattga
     5641 taccattctt tcattgtaac ttatttcccc tcttttcgcc actttcgttt tctgtcaggc
     5701 aaaaaactgt tctgccacag taatctttcc tatatatacg accggtcctg tcatgaaaat
     5761 tcttccatcc ttttcaaatt cgataaaaag atctccaccg tgcatatgta cggtcactgc
     5821 atcttcgact aatcccagac ggtgagaagc cgctgctgcc gcacaggctc cggtgccgga
     5881 agcaaatgta taccccgccc cacgttcata aatttcaacc tgtatatttt tttcatctac
     5941 gatctgacaa agctgcatat tgatacggtt tggaaaatat tttgcatttt ccacatatgg
     6001 tcctaaatgc agtgctttct cacgatctac cctctcaagc ataataacac aatttggatt
     6061 tcccatggat acacaggtcg cattataaaa attgtcgcag aaaaatatcg attctcctac
     6121 aacttctccc tcaaatccaa gtgccgggat ctgttctgcc tcaaagaccg catatcccat
     6181 atccacacgc atacagcttc cagcatcatc caaaaatgtt accagtgttt cccccgcttt
     6241 cgtggtcaga taatattgcc tttcttttac atatccggca tcttttaaat atcttgaaaa
     6301 aatccggatg ccattgccgc ttttttcagc ttcacttcca tccggattaa aaattcgtac
     6361 tttaattttt ttatcttcca taaccggtcc gtacaaaatt ccatctgcac cgacaccaat
     6421 attgcgtcta caaagctgcc ttatcaatct ctcatttaaa actacatcat ttttcttcgg
     6481 atcaaagatc agataatcat tgccaactcc atggtatttg cgaagtatga tctcagacat
     6541 cttgattcct ctgccatttt ccttgtgata tcatatgcag aataacagga aatggttact
     6601 ctactccccc attttcaaac aactggtgaa tatgttccgc cttctcgtgg aggatcttgt
     6661 caatctgatc tttcgtcact tcgtctaagt ctttctcctg accatattta cccgaatatg
     6721 cgttcgttgc tttattgtag tcttcctgca tatttggatc catagtctgg tcttgcgcat
     6781 tttctgcctc cgcagtctgc ttctgcatcc cgaaatcagc ctgcgttctc ggaatatagt
     6841 tcacattcca gtacttgata atacttcttg cgatacgttc ccgttcattt ctcttatcga
     6901 tcatgtcttt catcatcact gcaccacact ctattctgat ttttgatacc tttttatttt
     6961 agcacgaaac ccattggaaa aaaagttaat ttctgaataa aattcatcct tttgaagcat
     7021 gctctttatg gtaaagataa aattccggag gataaacagc atggcttctt ataaagtaga
     7081 aatctgcggc gtcaacaccg caaaactccc cattttgaaa gaagaggaaa aagatgctct
     7141 gtttgcacgg atcaaacagg gagataccgc cgccagagaa acttatatca aaggcaatct
     7201 caggctggta ttaagtgtca tcaaacgttt ttccggcaat cacgaaaatg tagatgatct
     7261 gtttcagatc ggctgtatcg gcctgatcaa gtccatcgac aacttcgatc cgacgatcgg
     7321 ggttaagttt tccacttacg cagttcccat gattataggt gagataagac gttacctgcg
     7381 cgacaataac tctatccgcg tcagccgttc cctgcgcgac actgcctaca aggcaatcca
     7441 caccaaagaa atactctcaa agacggaaaa caaagagccg actctcgacg aaattgccgc
     7501 cgaatccggc atttctaaag aggacatcgt tttcgccctc gatgccatcc agagtcctct
     7561 cagtctttat gacccggtct acaccgatgg cggtgacaca ctctatgtca tggaccagat
     7621 cagtgacaag aaaaaccggg aagaaaactg gattgaagag ctgtccctaa acgatgctct
     7681 cgaccggtta aacgaacgtg aaaattatat cttaaaactt cgcttttttg aaggaaaaac
     7741 gcagatggaa gtggctgacg agatccatat ctcccaggct caggtcagcc gcttagaaaa
     7801 atctgcgtta aaatccattc gtcattatct gtcgctctaa cgatcccatt tattgcacag
     7861 agcattgatc tgatctgcaa atttgccaag ttctttgttt ggcattccct cacacttatt
     7921 gataaccgta agaagtctct gacctgcagc aagcagtctt gcaaatacat tgctcgatgc
     7981 acggctcttc tctgttatct tcttctctgc ccgttctctg gatccttcgc gtacctgctc
     8041 gccggttgca aggtcaaatg catctcccgg gaacggcgca taggcctcat accccaaagt
     8101 atctttcaaa tgatccgcga actgctccgt aactttgtct tccccgtgta ccacaaatac
     8161 ttttttcggc ttattttcga atgctgccgc ccattttgtc agttgttcca catctgcgtg
     8221 gccgctgata cccggcaggt tctcgattct tgccgcaacc tcgattgtct caccaaagag
     8281 ccttacctct tttgcaccat ttaagagtga aaagccaagt gttcccggca cctgatatcc
     8341 cacgaataag atcgtggaat cttttctcca cagattatgt ttcaaatggt ggcggatacg
     8401 tcccgcctca cacattccgg atgcagagat aataactttg ggattatcat taaagttgat
     8461 catttttgac tcatcacttg tgatcgccat tttaagtccc ggaaatccga tcggattaat
     8521 cccctgctgc acaagtgctc tcgcatcttc gtcaaaacat tcttccacac tcttgttaaa
     8581 aatgcttgtc gcttcaaccg ctaacggact gtctatgtat acctcaaaat tttcaaattc
     8641 cggcagcaga tgctcactct tgatcctgcg gataaaataa agcatctcct gtgttctgcc
     8701 cacggaaaat gcaggaacga ccagattacc gccgcgttca tacaatgttt ctttgatcac
     8761 ttttgccagg gcgatcgcga aatccggagg tgtgttgtgt tttctgtcac cataggttga
     8821 ctccatgatc acataatcgg catctttgat gtattccgga tctttgatga gcggacggtt
     8881 acctggtccg atatcaccgg aaaatgccag ttttacctct gtaccatcat catccctcac
     8941 ccacatttca atgcttgagg atccaagcag atgacctgca tctacaaaac ggatctcaag
     9001 tccgtcacag actttgatct ttttctgata atcacacggc acaaaatggc tcagtacgct
     9061 catcgcatca ttcatatcat aaagaggcac cacttccggt tttccggccc gttttgcctt
     9121 acgattgcgc cattctgcct cgaacatctg gatatgtgca ctgtctttga gcataatgtt
     9181 gcagagttca ttggtcgcta aggtacagta tattttgccg cggaaaccat gattgtataa
     9241 aagcggcaat aatccggaat gatcaatatg tgcatgcgtc acaaatacat aatcgatcat
     9301 cgctgcattg accggaatct cctgatttgt gtacagatcc ggcccctgtt ccataccaca
     9361 gtccaccagt atatgcttat ctccaaagga tagataatga caactgcctg ttacctcatg
     9421 tgctgcgcct aaaaattcca ataccatatg aagtccccca ttctgtctgc ttttctttca
     9481 ttatactatt tttcagctat atgcacaata ttttttcata ttttatatat tttttaacta
     9541 ttttgtcatt ttaccagaca aaaacagaga gactttactc aagacgcacg atttcttttt
     9601 tcagtcttcc catgatcttt ttttccagtc tggatatgta ggactgggaa ataccaagca
     9661 tatccgcaac ctctttctgg gttttttcct ctccatcgat ggaatttaac ccaaaccgca
     9721 gttcaatgat catccgttcc ctgccagata gttttccaat cgctgtctta agcagccgat
     9781 gttccacatc cgtttcaatg tcgtgataga tcacgtcctc atcggttcct aagatatccg
     9841 aaagtaacag ctcatttccg tcccagtcca cgtttaaagg ctcatcaata gacacttcca
     9901 ttctcgtttt gctgtttcgc cgcagataca tcagaatttc attttcaatg catctcgaag
     9961 cgtaggtcgc aagtttgata tttttcccgg aattaaatgt gttgattgct ttgatcagac
    10021 cgatcgtacc gatagaaatc agatcctcca ccccgacgcc ggtattatca aatttttttg
    10081 caatatacac cacaagccgc aagttatgtt caatcagccg ttttcttgca atctgtccgc
    10141 tttcatcact ggtaagcatc tctatgcata ccgcctcatc ttcaccggca agcggcggcg
    10201 gaagtacctc tgcgcctccg atataatgca cctcatcctt tttctttcga aaaataccgg
    10261 gaaatatcat cgttcttatc tttggtatcg caaattttat gtacattttc aattccacct
    10321 taattcttat tttctgtctt gccgccttgt ggcataatgc tcgaagcatt taagagcatt
    10381 tcatattcct taccgtcaaa cagcatctta tctgcggttc caatcgctgc atgtgggatt
    10441 tttaccgcac gttttccctg aaaaacagtc atttcatcca catttgttac cgcgatcagt
    10501 ccatcctttt cccccagtga tcgatatggc acaaaacgaa ccagatcctt ttcttttgta
    10561 aagaattttt ccgccacaga tcctgataga atactgatct cctgtcctgt gtacggatcc
    10621 gtcagctgat tcccgctatc ccagtatgca cgcagtctga tatacctttc tccttttttt
    10681 aactctgcag gataaatatg atttccacaa acgcgccttt caccaaaaca gatcactgcc
    10741 gtaacaacta ccgctgccgc aacaagcatc tgtaaaattt cattttgcga aaatatatgc
    10801 tgttctaaaa gccactcaag cgcacctccc tgtatcacgc acataaaata ggtcacaacc
    10861 cagttttcta aataactgcg ttttccttcc caaccaaaac aaaaaaatac catccctgtg
    10921 tttaaaacaa aatgtgcgat caaaaaatac aggatcctgt tattgataaa gcacaccaga
    10981 aacagatgaa tcagcgaaaa catcagcgat accgcaaaca gccgcccggg atgtatcctc
    11041 cgtttcagca ggcagttgca tccaagtatt gccatatagt ccataaacag attttcaagc
    11101 aggaacacat ctgcataaaa tacatagatc tcgtctcacc ccttttctcc agactctttc
    11161 gtatctttac tgttattata aaacagtaca actttacttt ttgtcaaaac aggtactcca
    11221 aatcccgcaa atcatccctt attttcgaca agcgttgttc ttttctatat ataaaaagag
    11281 atttatgtgt tttctcttca aacacataaa tctcttttca gatgtataaa ctgctgctgc
    11341 agcccgcgta ctttgcaggc atatctgttg ttatgttttc taatatttta tctcagatat
    11401 tattttcttg aatttttaag gaaatccgga attttaatat ccattggctg tactgtgctc
    11461 tcaggctgac gcggtctctg aataccagaa aatgatggtg cagccgtctg tgtctgcgta
    11521 tgtgcctgta cacttgcacc aagatttgcc gcctgtctgt tgatgccagg tgttccaacc
    11581 ggtcttgtaa cgtttgttgt atttccatag cggagatccg gcataatctt gctcttcggt
    11641 gctgccgcat tctcaagtcc tgttgcgata actgtgatcg tagcttcatc tgtcatagac
    11701 tcatcatact tcgcaccaaa aataatgttt gcattatcac ctgcaagatc ctgaacatag
    11761 cttgctgcat cgttcgcatc catcagggaa atatcaccgg aaatattgat aataacatgg
    11821 gatgcaccat tgatcgtggt ctctaacagc ggactcgcaa ctgcaagttt gacagcttcg
    11881 attgctttgt catctccctt ggcattaccg ataccgatat gtgccatacc cttgtccttc
    11941 atgacagtgg aaacatcagc aaagtcaaga ttgatcagtg ccggcagatt gataaggtct
    12001 gtaattccct gaacagcctg ctgtaacact tcatctgcct tctttaaggc atccggcatg
    12061 gtcgtacgtc tgtcaacgat ctccagaagc ttatcattcg ggatcacgat cagtgtatca
    12121 acgctctctt ttaaacggtc aataccggaa agtgcattta acatacgctg ttttgcttca
    12181 aatttgaatg gttttgtcac aacgccgacc gttaagattc cctgctcttt tgcaatcttt
    12241 gcaacaaccg gtgctgcacc tgttccggtt ccgccaccca taccacaggt tacgaaaacc
    12301 atatccgcgc ccttcactgc tgcagataat tcttccatgc tttcctcagc ggctttctga
    12361 ccgatttccg gctgtgctcc tgctccaagt ccttttgtca gcttttcacc gatctggatc
    12421 agtgtcggtg ctttacagag tgccaacgcc tgtttatctg tatttactcc gataaactcg
    12481 actcccccga tactctcatc aatcattcta tttacagcat tattaccagc tcctcctact
    12541 ccgatcacga tgatctttgc actggtatcc gcttctgttg tcttaatctc cagcaaggta
    12601 gttcctcctt catttagctt aaaaaattac agctaaaaaa ctcatataat ctataatata
    12661 atttttctta caattaatca actgattttt caaaaaagat tacacttttt ttttacaaat
    12721 ctgcacggtc aaacacaata tctgtcgtat ccggcgtcca tgtctctaaa tgcagtatac
    12781 cggagagtcc cgacaactgt ggcataattg cggaaagtct cgcaattttc tgtgtcagat
    12841 aatcttctga accaacattg accgcaatcg ttccgtaagt gagctgtggc tgcattgcac
    12901 tgtcatagtg gatttcttcc ggttcaagtt catatttttt cagtagttgt gtcagtgtca
    12961 acagatttct cagcagtttt gtatcctcaa gcggcagttt ttcgtataaa accacactat
    13021 cacaggtaac tcccgtgatc tttggcactc cttcgattac atccgacgaa gtttccacaa
    13081 caaatccgtc tttatcaaag tacgcatatt gtccaagcgt atcaatataa aaactgccca
    13141 gaataccttt ttctgtaacc gaaatccgca atgtatgcgg atcatccagc gaaatttcca
    13201 tcgtatccac aaacggtact tccccgacat ccacaaaccg gtatttcaga tctacataca
    13261 gactgttcca cgaataatca tcgtccagca ccatattttt gatctggtcg gcagaataaa
    13321 gactgtttcc ttccacaact acattctgga ctgtaaatac ctttaccaca ataagtgccg
    13381 caagtgcaaa caacatcaga actaccagaa agatacagat cccgattctt cttctttttt
    13441 ttctttttct ctgttctttg atcctcataa tcaggcaacc tctaatttaa ttcccctcga
    13501 tacagaaagt gccagcccca tctcagccag caaaatcgat atggatgttc ctccataact
    13561 gataaacggc agtgatactc ccgtattcgg tattgtattt gttacaaccg caatattaag
    13621 cagtacctga atggacaaat gtgccataat accaactacg atcaatgcgc catacagatc
    13681 ggatgcattg tttgcaatga tcatcagacg ccagataata agcagataca aaagtatcag
    13741 acagactgca ccaaaaagtc caagttcttc acagataacc gaaaagatca tatcattttg
    13801 tgcctccggg ataaatccca gtttctgcat gctctctcct aacccttttc cgaaaaggcc
    13861 tcccgaaccg atcgcatata atccctgcag cgtctgatac cctttttcat aatcctccgg
    13921 gtgcagccag atcataacac gttccgcacg gtaagacgcc agcagaataa acagagcacc
    13981 aaaaaggcat actcctattc ccattaaaat aaactgtaaa tatttcggac tcgcaacaaa
    14041 taacatacag acagcaattc caaggataat gatcgccgta cttaagttat tatacgcaac
    14101 cactgccaaa accggtgaaa tcaaaagcat gatcttaagc agactcataa tttccccaat
    14161 gcgtttaggc gttttataga tgatcgtcgc aaggaaaatg ataaccgcaa tttttgcgat
    14221 ctcagatggc tggaactgga tcggtccgat cctgagccat ctcgactgtc cctttgcact
    14281 tgttccgaca aaaataaccg ctgtacaaag taccagcgcc acaaaatacg caagcgttga
    14341 aagctgcatc cagaacttat atgggattct tgaaataaaa agcattgcca ctattccaag
    14401 tgcacttgca tacatttgtc tttttacata atatgctgca tcgttaaatc ttgttgagcc
    14461 atagtaggaa ctggtactat ataacataat cagtccgaaa cataacaaaa atataatcag
    14521 aaataacagg ctgtaatcaa aataccggat cgatttttgt cttttttcat ttttccgtct
    14581 tcttgccata atttttcctc atttacacaa aacctgtctg atcaagcacc acaaccgttt
    14641 tattccggca gttccatgac atattgccgg aacagttctc cccgctgtgt ataatcctta
    14701 aaatctcccc agctcgcaca tgccggtgaa agcaatactg cttccccggg ctttgccagc
    14761 ctataacaga tatttaccgc ttcatttaat gtatcacagc atacaatatt ctcaaaacca
    14821 tgtttccttg cgcagactgc gatcttatct tttgtctgtc cgatcagtaa tagacatttt
    14881 actttcccat caaagctctc aatccacgca tcaaattcaa gatttttatc ataaccgccg
    14941 ccgatcagca gtgtcttacg attcattgaa ccgatcccgc ggattgccgc atccggattt
    15001 gtcgccttag aatcgttata gtacaaaaca ccatgcagat ctctcacaaa ctcaatgcgg
    15061 tgttttacac cccaaaactc ttttagtaca cgctgcacaa catctatcgg tgctcccata
    15121 caaagtgcag tgccggaagc tgccataaca ttttcataat tatgtatgcc cagaagtttt
    15181 aattcaccga catcaatcag gcgctgccgt tctgtttctt ttccagcgat ccagatcgta
    15241 ttttcctgca gataaattcc ctcttccaat ggtcttttac tgctgaaaaa caaaacgttt
    15301 acttttaatg tttcggcaaa tttccgaagt atttcatcct catagttgag cacacaggta
    15361 tcttcctttg tctgacactt tgtaatgctc tcctttgcac ggatatacgc ctccatcgtg
    15421 tgatgtctgt caagatgatc cggcgtaata tttaaaattg cagaaacaga cggatgaaat
    15481 gtttccatcg tttctaactg gaaactgctg atctctgtca ctgtgacggt ctgctctgta
    15541 gttttctcca caattgaagt ataaggaata ccaatatttc caaccacaaa gacttccgga
    15601 taacattttt ttaagatttc tcccaccagt gtcgtcgttg ttgtcttacc attt
//
