LOCUS       c00069_gnlPro..         9609 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DKNCEJAB_69.
ACCESSION   c00069_gnlPro..
VERSION     c00069_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 03:13:22
            Original ID  :: gnl|Prokka|DKNCEJAB_69
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9609
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..9609
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:4514]"
                     /cutoff="10000"
                     /detection_rule="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /neighbourhood="10000"
                     /product="acetate2butyrate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3..4514
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /neighbourhood="10000"
                     /product="acetate2butyrate"
                     /protocluster_number="1"
     cand_cluster    1..9609
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /kind="single"
                     /product="acetate2butyrate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..9609
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="acetate2butyrate"
                     /region_number="1"
                     /rules="(not (POR or POR_N or PFOR_II) and minimum(4,
                     [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF, ETF_alpha,
                     HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and minimum(1,
                     [EC1_2-faecali, ECH1_Enoyl_CoA_DH1, ECH1_Enoyl_CoA_DH2,
                     ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4, Thiolase_C]))"
                     /tool="gutsmash"
     CDS             3..452
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: Thiolase_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg69_1"
                     /sec_met_domain="Thiolase_C (E-value: 1.3e-52, bitscore:
                     166.3, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="AGNASGINDGAAAIVVMSEEKAKELGVTPMATWVAGALGGVEPEI
                     MGVGPVASTRKVLAKTGLSIDDMDLIEANEAFAAQSIAVARDLKFDMSKVNVNGGAIAL
                     GHPVGASGCRILVTLLHEMQKRDAKRGLATLCIGGGMGCSTIVER"
     CDS             546..1418
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: HCDH"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: HCDH_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg69_2"
                     /sec_met_domain="HCDH (E-value: 2e-35, bitscore: 111.1,
                     seeds: 68, tool: rule-based-clusters)"
                     /sec_met_domain="HCDH_N (E-value: 1.5e-63, bitscore: 203.6,
                     seeds: 60, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVGVIGAGTMGQGIAKAFAQVEGYEVALCDIKQEWAEGGKEKIK
                     KGYARLVEKGKMTQEAVDGILAKITPGLKEDLCKDCDLIVEAAFENMEVKKTTFKELDE
                     IAKPDCIFASNTSSLSITEIGNGLNRPMVGMHFFNPADRMKLIEVIAGVNTPDETVSAI
                     KKISEEIGKTPVQVNEAAGFVVNRILIPMINEAAFIKMEGVSDIAGIDAAMKLGANHPM
                     GPLELGDFIGLDICLAIMDVLYKETGDSKYRACPLIRKMVRGGNLGAKSGKGFYVYNAD
                     RTKTPVDAQ"
     CDS             1448..2602
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg69_3"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 6.6e-53, bitscore:
                     168.6, seeds: 49, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 2.4e-31, bitscore:
                     97.6, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 4.7e-40, bitscore:
                     126.6, seeds: 796, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDFTLDKKHEMARSLFKEFAETEVKPLAQETDETEAFPAETVKKM
                     QKYGFMGIPVPKEYGGQGCDPLTYVMCVEELSKVCATTGVVVSAHTSLCIDPIMTYGTE
                     EQKQKYVKPLATGEKLGAFALTEPGAGTDAQGAQTKAVLDGDEWVLNGSKCFITNGKVA
                     DVYIVIAITSITEDKRGRKKKNFSAFIVDKGAPGFSFGTKEKKMGIRGSSTYELIFEDC
                     RIPKENLLGPEGKGFPIAMHTLDGGRIGIAAQALGIAEGALDRAIAYTKERKQFGRSIA
                     QQQNTQFKLADMAARIEAAQLLVYKAAMAKATQKVYSVEAAKAKLFAAETAMAVTTEVV
                     QLFGGYGYIREYDVERMMRDAKITEIYEGTSEVQRMVISGALLK"
     CDS             2659..3441
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: ETF"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 159.1;
                     E-value: 3.7e-49)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg69_4"
                     /sec_met_domain="ETF (E-value: 7.1e-50, bitscore: 159.1,
                     seeds: 129, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIVVCIKQVPDTKGGVKFNPDGTLDRAAMLAIMNPDDKAGLEAA
                     LRIKDETGAKVTVLTMGLPKADAVLREALAMGADEAVLVTDRVLGGADTWATSTTIAGA
                     LRNLDYDLIITGRQAIDGDTAQVGPQIAEHLGLPVISYAADIKVEGDSVVVKRQYEDRY
                     HELKAKMPCLVTALSELNEPRYMTPGGIFDAFDKEVTVWGRADLKDVDDSDLGLKGSPT
                     KIAKASDKVAKGAGEKVNLDPAESVAYLIGKFKEKHII"
     CDS             3468..4514
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: ETF"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: ETF_alpha"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 161.3;
                     E-value: 7.7e-50)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg69_5"
                     /sec_met_domain="ETF (E-value: 1.5e-50, bitscore: 161.3,
                     seeds: 129, tool: rule-based-clusters)"
                     /sec_met_domain="ETF_alpha (E-value: 6.4e-39, bitscore:
                     121.7, seeds: 511, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALEEYKGVFVFAQQVDNVLDGVAFELLGKGKDLAKDLGTDVTAV
                     LIGSGVKGLADQLAEYGADKVIVVDDPELKDYRTEPYAHALASVINEFKPEIMLVGATA
                     IGRDLGPTVSARVKTGLTADCTSLEIGDFPLVAAPGKESEQKHNQLLMTRPAFGGNTIA
                     TIACPDNRPQMATVRPGVMQKIAPISGAKANVVEYNPGFTPNNRYVEILNIVKAVKSTA
                     NIMEAKILVSGGRGVGSKENFKLLEDLAEVLGGTVSCSRAVVENGWLPVDLQVGQTGKT
                     VRPQIYFAIGISGAIQHVAGMEDSDLIIAINKDEDAPIFDVADYGLVGDLNKIVPALTT
                     ALKAELGK"
     CDS             complement(4686..5045)
                     /locus_tag="ctg69_6"
                     /transl_table=11
                     /translation="MILDYITPNGNYDGLFSSGGLRIYHVDATLANDEYVTPYLTADNY
                     SPVYDSTNNGRRILRLVNNGNGFYRDGDVIGGTATGFGWYDNNGQLTIDTGYMITVDSV
                     SEDQKNCTITILTNN"
     CDS             complement(5071..5685)
                     /locus_tag="ctg69_7"
                     /transl_table=11
                     /translation="MIQKKNVLNTVPVICLGALLLGAAYGQLHTPMTPPPITALASDIL
                     PTTGNVRALVVVVDFADAKYDTDRRLSDEEISSYLFGTDNTEFYPCESLTSYFDRASYG
                     SLHMTGNVFHYTAKGTIASYEKTNDGYETLVREVLSGLNDTIDYTDYDSDGDGYIDALC
                     LSVPSRGNADFWYGCTASWWASTLPDLDGEKLRKLSDHTAH"
     CDS             5980..6588
                     /locus_tag="ctg69_8"
                     /transl_table=11
                     /translation="MNKKKFSTKFLVEMALLVAIILIMAFTPLGYIKTAGIEITLIVVP
                     VAVGAVTLGPTAGAILGGVFGFASFLRCFGLNAFGATLLGINPFLAFLVYVPTRILVGW
                     LTGLIYQGLRKTKLPYTASITVANLCCPLLNTTLFMGMLVIGFYQTEYIQSFVQTLGVS
                     NPFWFVLAFVGINGLVEAVVCFVVGTAISAALKKALKYN"
     CDS             6697..7305
                     /locus_tag="ctg69_9"
                     /transl_table=11
                     /translation="MTQKKFSTKYLVEMALLVAIILIMAFTPIGYIRTAGLEITLIVVP
                     VAVGAVTLGPAAGAILGGVFGITSFIQCFGMSPFGAALLGINGFLTFLVCVPTRILMGW
                     LTGLIYKGLRKTKLPSGASVTISNLCCPLLNTTFFMGMLVLGFYNTEYIQSFVSALGAK
                     NALLFILAFVGVNGLIEAIVCFIVGTAISAALKKALKYN"
     CDS             7434..7862
                     /locus_tag="ctg69_10"
                     /transl_table=11
                     /translation="MADAQSQQENESTQASRDIFAMDTYMNVTAYGVGANEAVRRAEEE
                     IERLDSLLSTGDQNSEIYQINQNGGGILSEDTAYLVERSLDLYQSTNGAFDIAIYPVMK
                     AWGFTDDNFRVPEEEELQELLTLFKAKGAGKNIKVKKM"
     CDS             8037..8699
                     /locus_tag="ctg69_11"
                     /transl_table=11
                     /translation="MQQNTGEKKSKNKEKRTRVIKIRITGGVILAIVIVCVILKILNAD
                     PSSVFLKNTKDAIIGEEGTVTTISKASLEKVFEISELSTVDYSYNAVARAYEEDGATPK
                     YYVAYEGTVTAGIDFSKIVIDIDEDTKIITITLPESEIQNTTVDFGSMDYIFENKKYET
                     ETVSQEAYELCKTDLARRAAKENDLMTLAKENAVTAVEALVDPWVQQIDGEYKVNIK"
     CDS             8711..9355
                     /locus_tag="ctg69_12"
                     /transl_table=11
                     /translation="MRKYRIIMILCVMSLFLVACTNKNDKTKVKMEETQEMETAAVLEP
                     DLAQIRSICDLATLECYYHNVAKSTKEKGSGLAHLGEKERKFWIEYTGVVKIGIEMSDV
                     KMDVNGTSVQITIPRAKIFQPEVKTIDVDDYIATSDSWFNQNQITAEEQTQAVNEAQDE
                     MVAAVEKNKTLLAGAQERAKTLIENYITQLGEATGVEYQVTWKYAENGTER"
ORIGIN
        1 cagcaggtaa cgcttccggt atcaacgatg gtgcagcagc aatcgttgtt atgagtgaag
       61 aaaaagcaaa agagcttggt gttacaccaa tggctacatg ggtagcaggt gctcttggtg
      121 gagttgagcc tgaaatcatg ggtgttggtc ctgttgcttc tacaagaaaa gtattagcta
      181 aaacaggttt atccattgat gatatggact taatcgaagc aaacgaagca ttcgcagctc
      241 agtctattgc agtagcaaga gatctgaaat tcgatatgtc aaaagtaaac gtaaacggtg
      301 gtgcaatcgc attaggacac ccggtaggtg cttccggatg ccgtatcctt gttacattac
      361 tgcatgagat gcagaagaga gacgctaaga gaggtcttgc tacactttgc atcggcggtg
      421 gtatgggatg ctctacaatc gttgagagat aatagttttt tatagtaatt cccggggaat
      481 gacttcccgg ggattgcatt tttcaaacat acagttaaca taattatttt caggaggtaa
      541 ccgaaatgaa ggttggcgtt attggtgcag gaactatggg acagggcatt gcaaaagcat
      601 ttgctcaggt agaaggatat gaagtagcac tttgcgatat caagcaggag tgggctgaag
      661 gcggaaaaga gaagatcaaa aaaggttatg caagattagt agaaaaagga aaaatgacac
      721 aggaagctgt tgatggcatc cttgcaaaaa tcactccagg tttaaaagaa gacctttgca
      781 aagactgtga tctgatcgta gaggcagctt tcgagaatat ggaagtaaag aaaactactt
      841 tcaaagaatt agacgagatc gcaaaaccag attgtatctt cgcttccaac acatccagtc
      901 tttctattac agagattgga aacggattaa accgtccaat ggttggtatg catttcttca
      961 acccggcaga ccgtatgaaa ctgatcgagg ttatcgctgg tgtgaatact ccggatgaaa
     1021 ctgtttccgc tattaagaaa atttctgaag agatcggaaa aactccggta caggttaatg
     1081 aggctgctgg tttcgttgta aaccgtatct taatcccaat gatcaacgaa gctgcattca
     1141 tcaaaatgga aggtgtttcc gatatcgctg gtatcgatgc agctatgaaa cttggtgcta
     1201 accacccaat gggaccgtta gagttaggtg atttcatcgg tcttgatatc tgccttgcta
     1261 tcatggatgt actttacaaa gagacaggcg acagcaaata tcgtgcatgc ccactgatcc
     1321 gtaagatggt tcgtggtggt aaccttggag caaagagcgg caagggattc tatgtataca
     1381 atgctgatcg tacaaagact ccggtcgatg ctcagtaaaa taaatattta tggaggaaaa
     1441 ttagatcatg gatttcactt tagacaagaa acatgaaatg gcgcgttcct tattcaagga
     1501 atttgctgaa acagaagtaa aaccgcttgc acaggaaaca gatgagacag aagctttccc
     1561 ggctgaaacg gttaagaaaa tgcagaaata cggattcatg ggaatcccgg ttccgaaaga
     1621 atacggcgga cagggttgtg atcctcttac atacgttatg tgcgtagaag agttatctaa
     1681 agtttgcgca accacaggtg ttgttgtatc tgcacataca tctctctgca tcgatccgat
     1741 catgacatac ggtacagaag agcagaaaca gaaatatgta aaaccacttg caacaggcga
     1801 gaagttaggt gcattcgcat taactgagcc gggtgctggt actgatgcac agggtgcaca
     1861 gacaaaagct gttttagatg gtgacgagtg ggtattaaac ggatctaaat gtttcattac
     1921 caacggtaaa gttgcagacg tttatatcgt aatcgcaatc acaagcatca cagaggataa
     1981 gagaggcaga aagaagaaaa acttctctgc attcatcgtt gataagggag ctccaggctt
     2041 ctcattcgga acaaaagaga agaagatggg tatccgtgga tcatctacgt atgagctgat
     2101 tttcgaagac tgcagaattc cgaaagagaa tctgttagga ccggaaggaa aaggtttccc
     2161 gatcgcaatg cacacacttg atggtggacg tatcggtatt gctgctcagg cacttggtat
     2221 cgctgagggc gcattagaca gagctatcgc ttatacaaaa gagagaaaac agtttggacg
     2281 ttcaatcgca cagcagcaga atacacagtt caagcttgct gatatggctg caagaatcga
     2341 agctgcacag cttttagttt acaaagctgc aatggcaaaa gctactcaga aagtatattc
     2401 tgtagaagct gcaaaagcga aattattcgc agcagagact gcaatggctg ttacaactga
     2461 ggttgttcag ttattcggtg gatacggata tatcagagag tacgatgtag agcgtatgat
     2521 gcgtgatgct aagatcactg agatctacga gggtacaagc gaagtccagc gtatggtaat
     2581 ctccggtgca ctgttaaagt aatttcgaat caatccgcgt aaaatttaaa catataaaac
     2641 ataaggagtg aaaaatacat gaatatcgta gtatgtatta aacaggttcc tgatacaaag
     2701 ggcggcgtta agttcaaccc ggatggaacg cttgacagag cagcaatgct tgctatcatg
     2761 aacccagatg ataaagctgg tcttgaagca gcacttagaa tcaaagatga gacaggagca
     2821 aaagttacag ttcttaccat gggacttcca aaggctgatg cagttcttcg tgaagcatta
     2881 gcaatgggtg ctgatgaagc agttcttgta acagaccgcg tattaggtgg agctgataca
     2941 tgggcaacat ctaccacaat cgctggtgca cttcgtaact tagactatga cctgatcatc
     3001 acaggacgtc aggctatcga tggtgatact gcacaggttg gtcctcagat cgctgagcat
     3061 cttggacttc cggttatctc ttacgcagca gacatcaaag tagagggtga ttctgttgtt
     3121 gtaaaacgtc agtacgaaga cagatatcat gagttaaaag caaaaatgcc ttgtctggta
     3181 actgctcttt ctgaattaaa tgagccgcgt tacatgacac cgggcggaat cttcgatgca
     3241 tttgacaaag aagtaaccgt ttggggcaga gcagacttaa aggatgttga cgattctgat
     3301 cttggtttaa agggatctcc tactaagatt gcaaaagcat ctgataaagt tgcaaagggt
     3361 gctggtgaga aagtaaacct tgatccggca gaatccgtag catatttgat cggtaaattc
     3421 aaagagaaac acattatcta ataaaaaaag gaaaagtggt gaataacatg gcattagaag
     3481 aatataaagg agtatttgtc tttgcacagc aggtagataa cgtattagat ggcgttgcat
     3541 ttgagttact tggaaaaggc aaagacttag caaaagattt aggtacagac gtaactgctg
     3601 tattaattgg ttctggtgta aaaggattag cagatcagtt agctgagtat ggtgctgaca
     3661 aagttatcgt agtagatgat cctgaattaa aagactacag aacagagccg tatgctcatg
     3721 cattagcatc tgtaattaac gagttcaaac ctgaaatcat gttagttggt gcaactgcta
     3781 tcggccgtga cttaggacct actgtttctg caagagtaaa aacaggtctg acagcagact
     3841 gtacatctct tgagatcggt gatttcccac tggttgctgc acctggtaaa gaatcagagc
     3901 agaaacacaa ccagttatta atgacacgtc ctgcatttgg tggtaacacc atcgcaacaa
     3961 ttgcctgccc ggacaaccgt cctcagatgg caactgtacg tccaggtgtt atgcagaaga
     4021 tcgctccgat cagcggtgca aaagcaaacg ttgtagagta caacccggga tttacaccaa
     4081 acaacagata tgttgagatc ttaaacatcg taaaagctgt taagagcaca gcaaacatta
     4141 tggaagcaaa gatccttgtt tccggtggtc gtggagttgg ttccaaagag aacttcaaac
     4201 ttttggaaga tcttgcagag gtacttggcg gtactgtaag ctgctcccgt gcagttgtag
     4261 agaatggctg gttaccagtt gatttacagg taggtcagac tggtaaaact gttcgtcctc
     4321 agatctactt tgcaatcggt atttccggag caatccagca cgtagctggt atggaagatt
     4381 ctgacctgat catcgcaatc aacaaagatg aagatgctcc aatcttcgac gtagctgatt
     4441 acggtctggt tggtgatctg aataagatcg ttcctgcttt aacaacagca ttaaaagctg
     4501 agttaggcaa ataatacata ggtgaataac ctgtaagata gaaagcccgt ctttcgtgtg
     4561 cggcttctgt gaggaagctg acaggaagga cgggcttttt gttgggagtt ggagaaaatt
     4621 tgcggctctt gtttggagtt ggaggaaatt tgaggctctt ggtcaggagt tgagggaaaa
     4681 tatacttagt tgtttgtcaa aatcgttatg gtacagtttt tctgatcctc agatacggag
     4741 tcgaccgtga tcatataccc ggtatcaatg gtcaactgtc cgttgttgtc ataccagcca
     4801 aagcctgtgg cagtgcctcc gatcacgtca ccgtcccggt aaaagccatt tccgttattg
     4861 accagtctta agatccgcct gccgttattg gtggaatcgt agacaggact gtagttatca
     4921 gcagtcagat agggggtaac gtattcgtcg tttgcaaggg tggcatcgac gtgataaata
     4981 cgaagtccgc cggaagaaaa cagaccgtca taattaccat tcggggtgat atagtcaagg
     5041 atcatgtatt ctgaaaaata actggaagca tcagtgcgcg gtatgatcag acagcttcct
     5101 taatttttcg ccatctaaat ccggcagggt ggaagcccac caggatgccg tacagccata
     5161 ccagaaatca gcattgcctc tgcttggaac agaaaggcag agagcgtcga tatagccatc
     5221 gccgtcagaa tcataatcgg tatagtcgat cgtatcattt aaaccggaaa gaacctcacg
     5281 caccagcgtt tcgtatccat cgttcgtttt ttcgtaggat gcgatcgtac ctttcgctgt
     5341 gtaatgaaat acatttccgg tcatatgcag tgatccgtat gaagcacggt caaaataact
     5401 agtcaggctc tcacagggat aaaattcagt attgtctgtg ccaaacagat aggaggaaat
     5461 ttcttcatcg gacaggcgtc tgtctgtatc atatttcgca tccgcaaaat cgaccacaac
     5521 aacaagtgct cggacattgc ctgtcgtcgg cagaatatct gaggcgagag ctgtaatcgg
     5581 tggcggcgtc attggcgtgt gaagctgccc gtatgccgcc cccaaaagca gggcaccaag
     5641 gcagataacc ggaacggtgt taagtacatt ttttttctgt atcatggtaa aaactctttt
     5701 cttataaata tatggttagc tttgcacgca aaaagcagaa agtcaatggc atttattgat
     5761 aattaaggaa acaataaaaa tataaaaaag tggtagtgca attctgagaa tggcacaatt
     5821 ttaggattaa cgcaatctaa gattgcggaa aattctgcca gatgttatac ttagtaacgt
     5881 tgcagagata caggatgccg gaaattcata ctgatctaca aatggctcgt cctgtgtttc
     5941 gtataaaatt acataaaaac gagaaaagag gaagggacta tgaacaagaa aaagttctcc
     6001 acaaagtttc ttgtggaaat ggcactttta gttgccatca ttcttatcat ggcttttacc
     6061 ccactcggat acattaagac ggcaggtatt gagattacac tgatcgttgt tccggtggcg
     6121 gtaggagctg ttacactagg accaacggca ggtgcaatct taggtggtgt atttggattt
     6181 gccagttttt tacggtgttt cggactaaac gcctttggtg cgacgctgct tggaattaat
     6241 ccgtttctgg catttctggt atatgtgccg acacgtattc tggtaggatg gctgaccgga
     6301 ttgatctatc agggactcag aaagacgaaa ctcccatata ctgcatcaat cacggtcgca
     6361 aatttatgct gtccgctttt gaatacgaca ttgtttatgg gtatgctggt gattggtttt
     6421 tatcagacgg agtatatcca gtcatttgtt cagacactgg gtgtcagcaa tccgttctgg
     6481 tttgtgcttg catttgtggg aatcaacgga cttgttgaag cggttgtatg ttttgttgta
     6541 ggaacggcaa tttctgcagc tttgaaaaag gcactgaaat acaattaaca gaatatgtta
     6601 aaaacgttaa tgcagcattg cggaaaaggt gtccaagtgc tatacttaat aacgttgcat
     6661 atgaattaca tattattaag aaaagaggaa gagactatga ctcagaaaaa gttttccaca
     6721 aagtatcttg tggagatggc acttttagtt gctattattc ttatcatggc ttttaccccg
     6781 atcggatata tcagaacagc aggtcttgag atcacgctga tcgtcgttcc ggtagcggta
     6841 ggagctgtta cattaggacc ggcagcaggt gcgatcttag gcggtgtgtt tggcattaca
     6901 agttttatcc agtgctttgg catgagtccg tttggtgcag cactgcttgg aattaacggc
     6961 tttttgacat ttctggtatg cgtacctacc cgtattttga tgggatggct gacaggtctg
     7021 atctataaag gacttcgcaa aacaaagctg ccatccggtg catctgttac gatcagcaac
     7081 ctttgctgtc cattacttaa cactacattt tttatgggaa tgttagtgct cggattttac
     7141 aatacagaat acatccagtc attcgtatcg gctctgggtg caaaaaatgc attgctgttt
     7201 attttagcat ttgtcggtgt gaacggactg attgaagcaa tcgtatgttt tatcgtagga
     7261 acggcaattt cagcagcttt gaaaaaggca ttaaaataca attaaataaa acatatgacg
     7321 atatgtagaa agatcccggt gttaccatta aggataacac tgggatcttt ctgcttataa
     7381 aaaaagcgtt gaagtttcct gttatataaa atgaggaaag cagcacacag aaaatggcag
     7441 atgcgcagag tcagcaggaa aacgaaagta cacaggcaag cagggatata tttgcaatgg
     7501 atacctatat gaatgtaaca gcttatggtg ttggtgcaaa tgaagctgtc cgacgggcag
     7561 aggaggaaat agaacgtctc gatagtcttt tatctaccgg agatcaaaat agtgagattt
     7621 atcagatcaa ccagaatgga ggaggaatcc tttcggagga taccgcttat cttgtggaac
     7681 ggtctttaga cctgtaccag tcaacaaatg gtgcatttga tattgcaata taccctgtga
     7741 tgaaagcatg gggatttaca gatgataatt tcagggtgcc ggaggaagaa gaattacagg
     7801 agcttctgac attgtttaag gcaaaaggtg ccggtaaaaa tatcaaggtt aaaaaaatgt
     7861 aaggcgcaga tatattttat tgtaaaatgg ggtctgaatc tgaaaagatt cagatccttt
     7921 tttgaactgt aaccaggctt cttctttctt ttattacaga aaatatggtg cttgtgagaa
     7981 aagaaacctt attgtagaat ggaatgtgta attgaacatt tgcggaggaa aaagcgatgc
     8041 agcagaacac aggcgaaaaa aagagcaaaa ataaagagaa gagaacacgg gtgataaaga
     8101 ttcgtatcac aggaggggtt attttagcaa ttgtgatagt gtgtgtcatt ctgaaaattc
     8161 tgaatgcaga tccttcatct gttttcttaa aaaatacaaa agatgcaatc atcggggaag
     8221 aaggaacggt aacaacgatt tcaaaagcgt cattggaaaa agtttttgaa atcagtgaac
     8281 tttccacggt agattattcc tataatgcag ttgcccgtgc gtatgaggag gatggtgcta
     8341 ctccgaaata ttatgtggca tatgaaggaa ccgttactgc aggaattgat ttcagtaaga
     8401 ttgtgatcga tattgatgag gatacaaaaa taatcaccat taccttgccg gagagcgaaa
     8461 tacagaatac aacggtggat tttgggtcaa tggattatat ttttgaaaat aaaaaatatg
     8521 aaacggaaac tgtatcacag gaggcatatg aattatgtaa aacagatctt gccaggcggg
     8581 cggcaaaaga aaatgatctg atgacattgg cgaaggaaaa tgcggttact gcggtagaag
     8641 cgctggttga tccatgggta caacagatag acggggaata taaagttaat attaaatagg
     8701 ggggaatgca atgagaaaat ataggataat aatgatacta tgtgtcatgt cattgttttt
     8761 agttgcatgt acaaataaaa acgataagac aaaagtgaaa atggaagaaa cacaagaaat
     8821 ggaaactgcg gctgtcttag aaccggatct ggcacagatc agatccatct gtgatcttgc
     8881 aacgctggaa tgttattatc ataatgtggc taagtccaca aaagaaaaag gatctggatt
     8941 ggcacatctg ggagaaaagg agagaaaatt ctggattgag tatacaggag ttgtcaagat
     9001 tgggattgaa atgtcagatg tgaaaatgga tgtaaatggt accagtgtac aaattacgat
     9061 tcccagagca aaaatttttc agccggaagt aaaaacaata gatgtggatg attatattgc
     9121 aacgtcagat tcatggttta accagaatca gatcacagct gaggagcaga cacaggcagt
     9181 aaatgaggca caggatgaaa tggtggcagc agtggaaaag aataaaacgt tattggcagg
     9241 cgcgcaggag cgtgcgaaaa cattgataga aaattatatc acacagttgg gggaagctac
     9301 cggtgtggaa tatcaggtta catggaaata tgctgaaaat ggaacagaaa ggtaagaaac
     9361 aataggatgc atgttctgta aacattctat tgtcatgaac aaaaattccc tgcatacaat
     9421 gtaaaaacaa gtattgcagg ggattttttg tgaaaaccta tattgaggaa agagctatgg
     9481 aaatagccag atatattatt gataataata cgacggtgcg tcaggcagcg aaacattttg
     9541 gaatcagcaa gagtacggta catacggtgg taacaaaata gaatgcttaa agaagatatt
     9601 aaaaaggca
//
