LOCUS       c00059_gnlPro..        10276 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OAABFJBE_59.
ACCESSION   c00059_gnlPro..
VERSION     c00059_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 23:50:42
            Original ID  :: gnl|Prokka|OAABFJBE_59
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10276
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10276
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[6960:9904]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      6961..9904
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..10276
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..10276
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             420..1268
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP_bind_3"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg59_1"
                     /sec_met_domain="ATP_bind_3 (E-value: 5.1e-08, bitscore:
                     21.6, seeds: 28, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKLEHLKEYLKGLGSVAVAFSSGVDSTFLLKVAHDVLGDKAIA
                     ITAQSCSFPKRELNEAKAFCEKEGIQHVICQSEELEIEGFSKNPPNRCYLCKKELFEKI
                     GDIAKKNGIEYIAEGSNMDDNGDYRPGLIAVKELGVKSPLREAKLTKAEIREYSKELGL
                     PTWDKQSFACLSSRFVYGETISEEKLGMVEKAEQLLLDYGFHQVRVRIHGSLARIEIMP
                     EEFPKLLEKNVREDIAKKFKEYGFTYVTMDILGYRMGSMNETLGENDKTTADSSLRGKN
                     E"
     CDS             1265..3052
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M24"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg59_2"
                     /sec_met_domain="Peptidase_M24 (E-value: 3.2e-43, bitscore:
                     136.5, seeds: 437, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVKERIAALRARMKETGIDAYLIPTDDFHGSEYVGEYFKCRKYI
                     TGFTGSAGTAVIMQDMAGLWTDGRYFIQAADQLEGTGITLFKMGEPEVPTVHEFLKKNL
                     TQGRCLGFDGRTVSAKEAAELEKMLDENGVSLSVDHDLAGDIWENRPALSCEPVTELDI
                     KWAGESRADKCARIRKAMEKKGADLFVLTSLDDIAWLLNIRGGDIHCCPVVLSYLVMTK
                     TEIRLFANEKAFQTDVLEALEKDGVTLFPYDSIYEYVKTFKKDKKVLLCKKKVNSRLVS
                     NIPADTRILDEENLTLLPKATKNPVEVENERIAHIRDGVAVTKFIYWLKKNVGRIPITE
                     LSAAEKLYEFRSEQEDFIDNSFDPIIAYGKHAAIVHYFATPETDIPLEPSGFLLADTGG
                     HYKEGTTDITRTVVMGPTTEEEKKYFTAVLRGTLNLGAARFLHGCTGVNLDILARQPLW
                     EMGEDFKHGTGHGVGYLLNVHEGPNSFRWKIVPGGNAVLEEGMITSDEPGYYREDGFGI
                     RHENLMVCKKAEKTEYGQFMCFEFLTMVPFDLDGVVPELMSVRERNLLNDYHAQVYEKI
                     SPYLNEEEKEWLKDATRAI"
     CDS             complement(3140..4906)
                     /gene_functions="resistance (resist) ABC_efflux (Score:
                     285.9; E-value: 3.7e-87)"
                     /gene_kind="resistance"
                     /locus_tag="ctg59_3"
                     /transl_table=11
                     /translation="MSRLTIKDPAKSKSSETFLKVLRFIGRYRFLLILSIILAAVSVIL
                     QLYVPILFGNAIDQVIAQHQVNFEMMWYYLSRILVMVILSSAATWLMNVINNRMTYQTV
                     KDIRAKAIRHIQVLPLSYLDGHSTGDIISRIIADTDILSDGMLLGFTQLFSGIVTIIGT
                     LIFMFSKNFWITLMVIVLTPVSFLVAKFISSHTFQMFRKQSDARGRQTALIEEMIGNQK
                     VVQAFGYEEKSSERFAKVNEELQECSLKAVFYSSLTNPSTRFVNNVIYACVALVGAFII
                     PGGRLTVGGLSVLLSYANQYMKPFNDISSVVTELQNALACAGRIFDLLEEEPEVAEASE
                     TLKDVKGEVDIKNVCFHYDESKKLIEDFNLHVKPGMRVAIVGPTGCGKSTFINLLMRFY
                     DVNAGSISVDGKQIRDITRHSLRSSYGMVLQETWIKNGTVRDNISIGKPEATDTEIIEA
                     AKLTHSWEFIRRLPKGLDTMLNEDSLSQGQKQLLCITRVMLCLPPMLILDEATSSIDTR
                     TELQIQEAFERMMEGRTSFIVAHRLSTIRNADLILVMKDGSIIEQGTHDELIAKGGFYH
                     TLYNSQFAKVSE"
     CDS             complement(4903..6717)
                     /locus_tag="ctg59_4"
                     /transl_table=11
                     /translation="MRSLTVYLKNYKKESILAPFFKFLEVVFDLIVPIVIAQIIDVGIA
                     NHDNKYIVQRFSILILMAALGLASTITAQFFAAKASVGFATELRQAVYDHVQHLSYTEL
                     DTLGTDTLITRLTDDINQVQNGLNMGLRLLLRSPFIVLGSMVMAFTIDFKCALVFAVAI
                     PFLFLVVFVIMFLSIPLFKKVQGKLDTVTGLTRENLTGVRVIRAFCREKEAVAEFDTRN
                     QELTKLNLFVGKLSALLNPVTYVLINIATVILIQKAGVEVNLGGMQQGQVVALYNYMAQ
                     MIVELIKLASLIITLNKSAACAGRVADILKVKSTMDYPSSSTYSAQISKDLATATADAS
                     LSENAIVFNDVTFEYSKAGAPSLSHISFSVKKGQTVGIIGGTGSGKTTLVNLISRFYDA
                     SKGTVLLDGQNIENYTRSDLRSRIGVVPQKAALFKGSIRDNLKWGREDASDEDLWQALT
                     TAQGKEVVEGKPGQLDFMLEQNGKNLSGGQKQRLTIARALVKKPEILILDDSASALDFA
                     TDAALRKSLNRLDWKVTTFLVSQRSSSIQQADLILVLDNGTLAGKGTHAELLRTCDTYR
                     EIYFSQFPEERARYSSVSAGNIMKEVTV"
     CDS             6961..8232
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg59_5"
                     /sec_met_domain="HGD-D (E-value: 3.2e-56, bitscore: 180.0,
                     seeds: 370, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIIETFGHYVENLTDKKPQSARRLLKTGWEAQNLKFRYMQDKRL
                     MPADRHLANLMMDTMLRPIQKPEDSVIVSIFTPCEMMQEVGLHPYNVEGFSCYLSASKA
                     ERAFLQQAENQGIAETLCSYHKTFLGAAQKGLLPKPKCIVYTNLTCDANLLTFRTLADF
                     YQVPVFAIDVPWNQTTENVQYVADQLKDLKIFLEKNTGKTISEDRLKERLACSKRTLEN
                     YKKYQQMRADRYVPSDLVTPLYAGMTNNILLGTAEEEKYTQMLLEDIKKAPAAKGKHIY
                     WMHTIPFWSDAVRQELCFSEKAQIVGCELAETCEPDFDPENPFEAMAERMVYHSLNGGA
                     LRRIEAGIRHAKQAGADGAVWFGHWGCKHTLGAAQLAKKKFEEAGLPLLILDGDGCDRS
                     HGGEGQTSTRLGAFLEMLGGAENE"
     CDS             8225..9904
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg59_6"
                     /sec_met_domain="HGD-D (E-value: 1.4e-17, bitscore: 53.1,
                     seeds: 370, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 5.6e-66, bitscore:
                     211.4, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTYYVCKYTPIELLESLGGECENFNHMPDGFDLADQVSHPNIC
                     GFGKTLLEGVMEGKIKELVLVSCCDTIRSVYDILLESGKLDFLYILDVLHCDSACSRER
                     MAVQLKGLAKAYAQYKGTEFDAGKFRAAFHAQEKITKSHIAVLGARMGQELFEMTSKAM
                     PLPVENDTCVHNRSVGNILPPEGASFDELMDWYAGEILGQIPCMRMMDPTGRKKLYNDP
                     SIAGIIYHTVKFCDFYSFEYAEIKNHTDVPLLKIESDYTIQSSGQLLTRLEAFAESIQP
                     ETLEQTIDGDTKGERKMGKGYFAGIDSGSTSTDVVILNKDHEIVTSIILPTGAGAAIGA
                     DRALAEALKEAGLQREDIDALVTTGYGRTAIKNGDKSITEITCHARGAHFLNPEVRTVI
                     DIGGQDSKVIRLDENGAVANFVMNDKCAAGTGRFLEMMARTMEMNLDQMSECGLEFKED
                     ITISSMCTVFAESEVVSLIAQNKATDDIVHGLNKAVAVKTAALTRRVGGEEKYMMTGGV
                     SKNKGLVKTLEEKLGTKLVISDKAQLCGALGAALFAADMADV"
ORIGIN
        1 tatctctggg tgttatttat aatatggggt agtggttaat tattatgtca tgtatgaatg
       61 gggaagaaac aaacggagaa ctgcttcaga aaaagaagta gacaaactgt aaataaagaa
      121 gttaagagag gctgttactt tagaaactat ttaaagaagt aacagaagtc ggggaagcgt
      181 tagaaaagat acaagaaaca taaatcaata ttgttcgttc tattttcagt aacacatttc
      241 gcaatgcgaa aaataggttg ctgaacagtc gttgcctata ttataatgaa gctatagcac
      301 cctgttaaat aatacatttg agaaagttca actttcacgc tctgttaagc cggatcaata
      361 tacattattt acgaggagtg ctacaggtac aataaaaaac ggacaagagg cagactgata
      421 tggaaaataa actggaacat ttaaaagaat atctgaaggg acttggcagt gtagcagttg
      481 ctttctcaag tggagtggat tctacattct tattaaaagt agctcatgat gtgctgggtg
      541 ataaggcgat tgcgattacg gctcaatcct gttctttccc gaaaagagag ctgaatgaag
      601 cgaaggcatt ctgcgagaaa gaggggattc agcatgtgat ctgccagtct gaggaattgg
      661 agattgaagg attttcaaag aatcctccga acagatgtta tttatgtaaa aaagaactgt
      721 ttgagaagat tggcgatatt gcaaaaaaga atgggattga atatattgca gagggatcaa
      781 atatggatga taacggcgat tacagaccag gtctgatcgc cgtaaaagaa cttggagtta
      841 agagcccgct acgtgaggcg aagctgacga aagcggagat cagagaatac tcaaaggaac
      901 tggggcttcc gacttgggac aaacagtcat ttgcctgtct gtcctccagg tttgtctatg
      961 gagagaccat cagtgaagaa aagcttggaa tggttgagaa agcagagcag cttttacttg
     1021 actatggatt ccatcaggta cgtgtccgta ttcacggttc acttgcaaga attgagatca
     1081 tgccggagga atttccgaaa cttctggaaa aaaatgtccg agaggatatt gcaaagaaat
     1141 ttaaggagta tggattcact tatgtgacca tggatattct gggatatcgt atgggaagta
     1201 tgaacgaaac acttggcgaa aatgacaaaa cgactgcaga tagcagcctt aggggtaaaa
     1261 acgaatgaca gtaaaagaga gaatagcagc acttcgtgca cgcatgaaag agacaggaat
     1321 tgatgcatat ctgattccta cagatgattt tcatggttca gaatatgtag gtgaatattt
     1381 caaatgcaga aaatatatca caggatttac cggttctgca ggcactgcgg tgatcatgca
     1441 ggatatggca ggattatgga cggatggacg ttattttatc caggctgcag atcagctgga
     1501 gggaacagga attactttat ttaaaatggg tgaaccggaa gttcccacag ttcatgaatt
     1561 tctgaaaaaa aatctgacac agggaaggtg tctgggattt gacggacgta ctgtcagtgc
     1621 aaaagaggca gcagaattgg agaaaatgct ggatgaaaac ggtgtgtctc tcagtgttga
     1681 tcacgatctg gcaggcgata tatgggaaaa ccgtccggca ctttcctgtg aaccggttac
     1741 agagctggat ataaaatggg caggagaatc cagagctgat aaatgcgcaa gaatccgcaa
     1801 agcaatggag aagaagggtg cagatttatt tgtactgact tctctggatg atattgcctg
     1861 gctgttaaat atacgtgggg gagatatcca ctgttgtccg gtggttcttt cttatcttgt
     1921 aatgacaaaa acagagatca gactttttgc aaatgagaaa gcctttcaga cagacgtact
     1981 ggaagcgctg gaaaaagatg gtgtgaccct ttttccctat gacagtatct atgagtatgt
     2041 gaaaacattt aaaaaggaca aaaaagttct tctctgcaaa aagaaagtca acagtcgtct
     2101 ggttagcaat attccggcag acacccggat tctggatgaa gaaaatctta cacttcttcc
     2161 caaggcaacg aagaatcctg ttgaggtgga aaatgaacgc attgcgcata tcagagacgg
     2221 agttgcagtt acaaagttca tatactggtt aaagaagaat gttggaagga ttccgatcac
     2281 agaattaagt gcagcagaaa agctgtatga attccgttcg gaacaggagg atttcataga
     2341 taacagtttt gatccgatta ttgcctatgg aaagcatgct gctattgtac attattttgc
     2401 aacacccgaa acggatattc ctctggaacc atccggcttt cttctggcag atacaggagg
     2461 acattataaa gagggaacca ctgatattac ccgtactgtt gtcatgggac cgactactga
     2521 ggaagagaaa aagtacttca cagcagtttt gcggggaact ctgaatctgg gagctgccag
     2581 atttcttcat ggctgtaccg gtgtaaatct ggatattctg gcgagacagc cgctgtggga
     2641 aatgggagag gattttaaac atggaaccgg tcatggagta ggatatcttc tgaatgtcca
     2701 tgaaggaccc aatagcttcc gatggaaaat tgttccgggt ggaaatgcag tgctggagga
     2761 gggaatgatc acctctgatg agccgggata ttacagagag gatggatttg gaatccgtca
     2821 tgaaaatctg atggtctgca aaaaagctga aaaaacagag tatggtcagt ttatgtgctt
     2881 tgaatttctg actatggtac cttttgatct ggatggagtg gtgccggaac tgatgagtgt
     2941 ccgggaacgt aaccttctca atgattacca tgcacaggta tatgagaaga tttctccgta
     3001 tttgaacgaa gaagaaaaag aatggctgaa agatgctacc cgggcaatct gataaaaata
     3061 aaaaaacatt ttacaaaatc aaaaagagga acagccgtga tggacagctg ttcctttttg
     3121 atttattatc tggtttgttt tattcagaaa cttttgcaaa ctggctgtta tataaagtat
     3181 ggtaaaatcc accttttgca atcagctcat catgagtacc ctgctcaatg atacttccgt
     3241 ctttcataac aagaatcaga tctgcatttc ggatggttga aagcctgtga gctacgataa
     3301 agcttgttct tccctccatc attcgttcaa acgcttcctg aatttgtaat tctgttcgtg
     3361 tatcaatact ggaagtggct tcatccagga tcagcatcgg aggcagacag agcataactc
     3421 gtgtgataca cagcagctgt ttctgtccct ggcttaagct gtcttcgttg agcatggtgt
     3481 ccagtccttt aggaagcctc cggataaatt cccagctgtg ggtaagcttg gctgcttcga
     3541 tgatttcagt atctgtagct tccggttttc caatcgagat attgtcgcgg acagttccgt
     3601 ttttgatcca tgtttcctga agcaccatac catagctgct tctcagagaa tggcgggtaa
     3661 tgtctctgat ctgtttgccg tcaacggaaa tagatccggc atttacatca tagaatctca
     3721 tcagaaggtt gataaaggtt gacttaccgc atccggtagg tcctacaatg gcaacgcgca
     3781 tacctggttt tacatggaga ttaaagtcct caatcagttt ctttgattca tcataatgga
     3841 agcacacatt cttaatatct acttcaccct ttacatcttt cagtgtctca gaagcctctg
     3901 caacttccgg ttcctcctcc agcagatcga agattctgcc tgcacaggca agagcattct
     3961 gaagttctgt aacaacggaa ctgatatcat tgaatggttt catatactgg ttggcatagg
     4021 agaggagtac ggaaagtcct ccgactgtca gtctgcctcc agggataatg aatgcaccca
     4081 ccagtgcaac acaggcataa ataacattat tgacaaaacg ggtggaaggg tttgtcaggc
     4141 tgctgtaaaa aacagccttc agactgcatt cctgtaattc ttcgttaacc tttgcaaagc
     4201 gttcagaaga tttttcctca tatccaaaag cctgaacaac cttctggttt ccaatcatct
     4261 cttcgatgag agcagtctga cgtcctctgg catcgctttg cttccggaac atctggaagg
     4321 tatgggaaga aataaatttg gccaccaaaa agcttacggg ggtcaggaca atgaccatca
     4381 atgtaatcca gaagtttttg gagaacatga agatcagtgt tccgatgatc gttacgattc
     4441 cggaaaaaag ctgggtaaat ccaagcagca taccatcgga tagaatatct gtatctgcga
     4501 taatacggct gatgatatct ccggtactgt gtccgtcaag gtaagagagg ggaagtacct
     4561 gaatgtgtcg gatggctttg gcacggatat cctttactgt ctggtaggtc atgcggttat
     4621 tgatcacatt cataagccac gtggcagcag aagagaggat gaccattaca aggatacgtg
     4681 acaggtaata ccacatcatt tcgaagttta cctgatgttg ggcaatgacc tgatcaatgg
     4741 catttccgaa taggattggg acatacagct gaaggataac ggaaactgct gccagtatga
     4801 tactgaggat cagcagaaaa cggtatcttc cgatgaaacg cagtacttta agaaaagttt
     4861 cgctgctttt gcttttagca ggatctttta ttgttaatct gctcatacag tcacctcctt
     4921 cattatatta cctgcagata cagaggagta tctggctctt tcttccggaa actgagagaa
     4981 gtagatttcc cggtaagtat cacaggtacg cagcagttca gcatgagtac ccttacctgc
     5041 cagagtaccg ttatcaagga caaggatcag gtctgcctgc tgaatgctgg aggaacgctg
     5101 ggataccaga aatgtagtta ctttccagtc aagtctgttg agagacttac gcagtgctgc
     5161 atcagtggca aagtccaggg cactggcact gtcatccagg atcaggattt caggtttttt
     5221 taccagggca cgggcaatgg taagtctttg tttctggccg ccggaaaggt ttttaccgtt
     5281 ctgttccagc ataaaatcaa gctgtcccgg tttaccctct actacctctt ttccctgtgc
     5341 tgtggtaagt gcctgccata gatcctcgtc agaggcatct tcccggcccc atttcagatt
     5401 gtctcggata gagcctttga aaagagctgc cttctgtgga acaacgccga ttctggagcg
     5461 gagatcactt ctggtgtaat tttcaatatt ctgaccatcc agcagaacag ttcctttgct
     5521 ggcatcatag aatctggaga tcagatttac cagagtggtt tttccgcttc ctgtaccacc
     5581 gataatacct acggtctgtc ccttttttac agaaaaactg atatgggaaa gactgggggc
     5641 accggctttg ctgtactcaa aggttacgtc attgaatacg atggcatttt cagaaagtga
     5701 tgcatcagca gttgctgttg caaggtcctt cgatatctga gcagaatatg tggaggaaga
     5761 agggtaatcc atagtagatt tcactttcag gatatctgcc acacgtcctg cgcaggctgc
     5821 agatttgttc agggtgatga tcagggaggc aagcttgatc agttccacga tcatctgagc
     5881 catatagtta taaagggcaa caacctgtcc ctgctgcata ccgccaagat ttacttctac
     5941 tcctgctttc tggatcagaa taacagtagc aatattgatc agtacgtaag tgaccggatt
     6001 taacaaagcg gaaagctttc ctacaaagag atttaacttt gtcagctcct gattgcgggt
     6061 atcaaattct gcaactgcct ctttttcgcg gcagaatgca cggataacgc ggacgcctgt
     6121 aaggttttct ctggtcagtc cggttactgt gtccagtttt ccctgtacct ttttaaacag
     6181 aggaatactg agaaacataa tgacaaagac aaccagaaac agaaagggga tcgcaacagc
     6241 aaaaaccagg gcacatttaa agtcaatggt aaatgccatg accatggacc caagtacgat
     6301 aaacggactt cgaagaagaa gacgaagccc catgttcagt ccgttctgga cctgattgat
     6361 atcgtcggta agtcttgtga tcagggtgtc tgttcccagt gtatccaact ctgtatagga
     6421 cagatgctgt acatggtcat aaactgcctg tcttaattct gtggcaaagc ccacgctggc
     6481 tttagcggca aagaactgag ctgtgatggt actggcaaga ccaagagccg ccattagtat
     6541 aagaatagaa aatctctgga caatgtattt gttgtcatgg tttgcaatac ctacatcaat
     6601 gatctgtgca atgacgatag gcacgatcag gtcaaataca acctccagaa atttaaaaaa
     6661 tggcgcaagg atgctttctt ttttgtagtt ttttaaataa accgtcaatg aacgcatttt
     6721 aaaaattcct tcctttcgta aaaatctttc ctatattatt ccttcctttt tttgaaaaat
     6781 aatacattca aaagtgtatc atttaagact tttttgtcaa gaagaatgtg caaaaacagg
     6841 tgaactttgg agaaaattca gcttgacttc aaaaaaagat attactaaaa tattccgtag
     6901 cgctatttgt acgctggcaa ctgataaatt attattacca taatgaggaa gagacagact
     6961 atggagatta ttgagacatt tggtcattat gtggaaaatc tgacggataa aaagcctcag
     7021 tcagcccgcc ggctgttaaa aaccggctgg gaggcgcaga atctgaagtt ccgttatatg
     7081 caggacaaga gactgatgcc tgcagacagg catcttgcaa atctgatgat ggataccatg
     7141 ctgcggccca ttcagaaacc ggaagattct gttattgtaa gtatttttac accctgcgaa
     7201 atgatgcagg aggtgggatt acatccctat aatgtagagg gattttcctg ctatctttct
     7261 gcaagcaaag cagagagggc gtttctgcag caggcagaga atcagggaat tgcagagaca
     7321 ctgtgcagtt atcacaagac atttcttggt gcagcgcaga aaggacttct gccaaagccc
     7381 aaatgtattg tttataccaa cctgacctgc gatgctaacc tgctcacctt ccggaccctg
     7441 gcagattttt accaggtacc tgtatttgcc attgatgtac catggaatca gaccacagag
     7501 aatgtacagt atgtggcaga tcagttaaag gatttaaaaa tatttctgga aaaaaataca
     7561 ggaaaaacaa tctctgagga cagattaaag gaacgtcttg cctgcagtaa gcggactctg
     7621 gagaattaca aaaaatatca gcagatgcgt gcagacagat atgtgccctc tgatctggtc
     7681 acacccttgt atgcaggaat gacaaacaat atccttctgg gaacagcaga agaagagaag
     7741 tatacacaga tgcttcttga agatattaag aaagcaccgg cagcgaaagg gaagcacatt
     7801 tactggatgc ataccattcc attctggtcg gatgcagtgc gccaggagct ttgcttcagt
     7861 gagaaagccc agatcgtagg atgtgaactt gcagaaacct gtgagccgga ttttgatcct
     7921 gagaacccct ttgaagcaat ggcagaaaga atggtatatc attcactgaa cggaggtgcc
     7981 cttagaagga ttgaagccgg tatccgccat gcgaaacagg caggagcaga cggtgctgtg
     8041 tggtttggac attggggatg taaacatacg cttggtgcgg cacagcttgc aaagaagaag
     8101 ttcgaggaag ccggtctgcc ccttttgatc ctggacggtg acgggtgtga tcgaagccat
     8161 ggaggagaag gacagacttc caccaggctg ggagcttttc tggaaatgct gggaggtgct
     8221 gagaatgaat aaaacttatt atgtctgtaa atataccccc attgagcttc tggaatctct
     8281 tggcggggaa tgtgagaact ttaaccatat gccggatggc tttgaccttg cagatcaggt
     8341 ttcccatccc aatatctgcg gttttggaaa aacacttctg gaaggagtca tggaggggaa
     8401 aatcaaggaa cttgtcctgg tgagctgctg tgatactatc cggagtgtct atgacattct
     8461 gcttgaaagc ggcaagctgg attttctcta tattttggat gtgcttcact gtgacagtgc
     8521 ctgcagcaga gagcgtatgg ctgtacagtt aaaagggctg gcgaaggctt atgcacagta
     8581 caaaggcaca gagtttgatg ccggaaaatt ccgggctgct ttccatgcac aggagaaaat
     8641 cacaaagtcc catattgcag tgcttggcgc cagaatgggg caggaattat ttgaaatgac
     8701 cagcaaggct atgcctcttc ctgtagagaa tgatacctgc gtgcataacc gttctgtggg
     8761 aaatatactt ccaccggagg gtgcttcttt tgatgagctg atggactggt atgcaggtga
     8821 gattctgggg cagattccat gtatgcgtat gatggacccg acaggtcgta agaagcttta
     8881 taatgatccg tctattgcgg ggattattta tcatacagtg aagttttgtg atttttacag
     8941 cttcgaatat gctgagatca agaatcatac agatgtacct cttttaaaaa tcgaatcaga
     9001 ttatactatt cagagcagcg gtcagcttct taccagactg gaagcttttg cagagagcat
     9061 tcagcctgaa acactggagc agaccataga tggagacaca aaaggagaga gaaaaatggg
     9121 aaaaggttat ttcgcaggga ttgacagtgg ttccaccagt acagatgtgg tgattttaaa
     9181 taaagatcat gagattgtga ccagtattat cctgcctaca ggagcaggag ctgctatcgg
     9241 agcagaccgt gcccttgcag aggcattgaa ggaggccgga ttgcagagag aagatattga
     9301 tgcgctggtt actaccggat acggacgtac agctattaaa aatggtgata agagtatcac
     9361 agagatcacc tgtcatgcaa gaggtgcgca tttcctgaat ccggaagtcc gtactgttat
     9421 tgatattggc ggacaggaca gcaaggtgat ccgactggat gagaacggtg cagttgcaaa
     9481 ctttgttatg aatgacaaat gtgcggcagg aaccggacga tttctggaaa tgatggcacg
     9541 taccatggaa atgaatctgg atcagatgag cgaatgtggg ctggaattca aagaagatat
     9601 tacaatttcc agtatgtgta cagtatttgc agaatcagaa gttgtatccc tgatcgccca
     9661 gaataaggca acagatgata ttgtccatgg cctgaataag gcggttgccg taaagactgc
     9721 cgcccttacc agacgtgtgg gcggtgagga gaaatatatg atgaccggtg gtgtttctaa
     9781 gaataagggt ctggtaaaga cactggaaga gaagcttgga acaaagctgg tgatcagtga
     9841 caaggctcag ctttgcggtg cacttggcgc agcactgttt gcagctgata tggctgatgt
     9901 ataaaaatta tttaaatatc cagggatttt acaaggtgga aatctctgga atttttatac
     9961 tttttttata aaagtttaat tttctattga cgagttcaaa tttaagagct atagtatacc
    10021 acagtaacag caaattaacg aggtgaagtt tgcaggaaag aggaagccac acaaaaggct
    10081 atacccgccg aaggagtaaa actctcaggt tccctggatg cagggaagaa ctgcaaatgg
    10141 atcgtttctc tggagacacc cgttagatcg ggggccgaag gtgcaaataa cacggaatgc
    10201 tgataacttc ccacaattgg ttatctgacc cgtgtcttga atctctcagg caaaaggaca
    10261 gaggatgctt tatcat
//
